PREDECISIONAL – DRAFT - INTERNAL

Pesticide Prioritization Framework for the U.S. NationalResidue Program 

FSIS continues to identify analytes of high public health concern to enhance the NationalResidue

Program (NRP). Through our regular interagency meetings, FSIS works closely with the Environmental

Protection Agency (EPA) to determine pesticides for inclusion into the testing program. FSIS uses a riskbased prioritization approach to develop a framework and rank pesticide residues based on relative

public health concern. This approach is applied to a comprehensive list of pesticides that are used 

domestically and internationally (in countries that are eligible to export to the United States) and 

includes all pesticides with tolerancesestablished by EPA for FSIS-regulated products. For pesticide

residues with EPA-established tolerancesin meat, poultry and egg products the associated U.S. Code of

Federal Regulations (CFR) citation for the tolerance islisted. Through this process, FSIS ensures that all

pesticides, including all pesticides with an EPA-established tolerance, are considered for inclusion in the

NRP, while allowing the Agency to focus its analyticalresources on the highest-priority pesticides. Due

to analytical capabilities, FSIS does not currently testfor some of the pesticides that are listed in the in 

the Agency's pesticide prioritization framework. FSIS notes that by not testing for these pesticides, the

Agency does not know the extentto which exposures to these pesticides occur in the foods that FSIS

regulates. As analyticaltechniques and methodologies advance, FSIS works closely with the EPAto

prioritize pesticides and with the AgriculturalResearch Service to evaluate the addition of additional

pesticide residues into themulti-residue pesticide method. Currently, FSIS analyzesfor 108 of the 482

ranked pesticide residues. Detailson the analyticalmethod can be found in the FSIS Chemistry 

Laboratory Guidebook.

The pesticides are ranked based on various factorsas described below:

The categoriesof " Usage (S),” "Bioavailability (B),” “Health-Based Guidance Value (H),” and 

"Carcinogenicity (C)" were employed as predictors of risk per unit of consumption from pesticides in 

animal products. The model uses a 6-point scale to give variability between overall score. The ranking

list developed assesses both the toxicity and exposure of 482 pesticide residues and rank each residue

based on potential human health risk. FSIS is analyzing for 108 of the 482 ranked pesticide residues. For

each chemical, the relative risk assessment can be summarized with the following equation. 

RRRRRRRRRRRRRRRR ppppppRRRRpp hhRRRRRRRRhh rrRRrrrr= EEEEppEErrpprrRR × TTEEEERRppRRRRTT

The variables S, and B represent pesticide exposure and variables H and C represent the pesticides

toxicity. By multiplying weighted average exposure (S, and B)to the weightedaverage of toxicity (H and 

C), a rough estimate of the relative risk per unit of consumption represented by each pesticide or

pesticide class is obtained.

RRRRRRRRRRRRRRRR pppppp pp hh hh rr rrrr = �

SS + BB

22 � × �

HH+ CC

22 �

1. Usage (S) 

The U.S. Geological Survey (USGS) publishes the annual county-level pesticide use survey. The survey

estimated pesticide usage (in kilograms (kg)) in the US 2016. FSIS believes this data is important

because the increase usage of pesticides increases the probability of the pesticide being present in the

food supply, including FSIS-regulated products.

Categorical distribution of pesticide usage (in kg)

6 If usage is > 1,000,000 kg
PREDECISIONAL –DRAFT - INTERNAL

5 If usage is > 750,000 and ≤ 1,000,000 kg

4 If usage is > 500,000 and ≤ 750,000 kg

3 If usage is > 250,000 and ≤ 500,000 kg

2 If usage is > 1,000 and ≤ 250,000 kg

1 If usage is ≤ 1,000 kg

2. Bioavailability (B)

The bioavailability (B) factor has been adopted from the previously published blue book ranking models. 

This is a measure of a chemical’s relative affinity for fat, as measured by the octanol-water coefficient, 

log Kow. The log Kow is defined as the ratio of a compound’s concentration in a known volume of noctanol to its concentration in a known volume of water after the octanol and water have reached 

equilibrium (Leo 1971). Compounds that have a high affinity for octanol tend to bioaccumulate in body 

fat and can easily cross the plasma membrane of cells. This is a concern, in that the chemical will stay in 

the fat of FSIS-regulated products. The log Kow was calculated using EPA’s EPISuite (v4.11) for chemicals 

lacking published log Kow. 

Categorical distribution of bioavailability

6 If log Kow is > 5

5 If log Kow is > 4 and ≤ 5

4 If log Kow is > 3 and ≤ 4

3 If log Kow is > 2 and ≤ 3

2 If log Kow is > 1 and ≤ 2

1 If log Kow is < 1

3. Health-Based Guideline Value (H)

Before pesticides are approved by EPA, each pesticide has to go through a rigorous testing process. It is 

at this stage that EPA determines if the pesticides have the potential to enter our food supply. Based on 

this possibility, dietary acute reference dose (aRFD) and chronic reference dose (cRFD) are determined.

The cRFD is an estimate (with uncertainty spanning an order of magnitude or greater) of a daily oral 

exposure level for the human population, including sensitive subpopulations, that is likely to be without 

an appreciable risk of deleterious effects during a lifetime. The aRFD and cRFD are calculated by dividing 

the no-observed-adverse-effect-level (NOAEL) (i.e., the highest dose that gave no observable adverse 

effect) or the lowest-observed-adverse-effect-level (LOAEL) (i.e., the lowest dose at which an adverse 

effect was seen) by uncertainty factors (UF). UF’s are used to account for differences between different 

humans (intraspecies variability) and for differences between the test animals and humans (interspecies 

extrapolation). If the LOAEL is used, an additional UF is required. These scores represent EPA’s 

professional assessment of the extent to which the chronic dietary exposure to this compound may 

exceed EPA's level of concern. For each chemical, the level of regulatory concern was determined by 

the toxicological endpoint, chronic population adjusted dose (cPAD). 

Categorical distribution of the cPAD

6 If HBGV is < 1E-6

5 If HBGV is < 1E-5 and ≥ 1E-6 

4 If HBGV is < 1E-4 and ≥ 1E-5

3 If HBGV is < 1E-3 and ≥ 1E-4

2 If HBGV is < 1E-2 and ≥ 1E-3

1 If HBGV is ≥ 1E-2

4. Carcinogenic Potential (C)
PREDECISIONAL –DRAFT - INTERNAL

The carcinogenic potential (C) factor is based on a report published by EPA’s Office of Pesticide 

Programs, Chemicals Evaluated for Carcinogenic Potential(Dec 2018). The report lists the 

carcinogenicity hazard for pesticides, with no consideration of exposure information. The ranking is 

based on an EPA lettering system, designating the degree of carcinogenic potential. Similar to the 

previously mentioned variables, the carcinogenic potential will be classified based on the weight of 

evidence narrative in the cancer risk assessment. 

Categorical distribution of the carcinogenic potential

4 or 6 Likely to Be Carcinogenic to Humans,

Probable Carcinogenic to Humans

 3 Suggestive Evidence of Carcinogenic Potential 

Possible Carcinogenic to Humans 

2 Not Classifiable as to Human Carcinogenicity

1 Evidence of Non-carcinogenicity for Humans, 

Not Likely to Be Carcinogenic to Humans

For chemicals classified as 1) likely to be carcinogenic to humans and 2) probable carcinogenic to 

humans, the respective cancer slope factors (Q*) were used to determine the score. For Q* > 1, the 

chemical was given 6 points, and for Q*<1, the chemical was given 4 points.

Chemical Identification and Prioritization Framework Model Results

The chemical identification and prioritization framework determines an overall score for each pesticide 

residue (482 pesticide residues) evaluated and rank residues based on relative public health impact. The 

table includes each chemical residue, the respective classification type, relative public health scores,

current sampling status, and current statutory U.S. Code of Federal Regulations (CFR) for each pesticide 

residues.

Table Legend:

Rank – Chemical Prioritization rank based-on relative public health importance

Chemical – Name of pesticide residue or active metabolite

Type – Classification type of each residue

S – Usage 

B – Bioavailability

H – Health-Based Guidance Value

C – Carcinogenicity

Score – Final Score

FSIS Sampling – Indicates whether the residue is included in the FY2019 NRP

EPA Ranking – Priority list developed by EPA, which summarize pesticide analytes monitored in meats 

and poultry as part of USDA’s Pesticide Data program (PDP)

Authority – All pesticides with EPA-established tolerances in FSIS-regulated products include a citation 

to the U.S. Code of Federal Regulations (CFR) 
PREDECISIONAL –DRAFT - INTERNAL

Pesticide Ranking Based on Relative Public Health Impact

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

1 Tribufos (DEF) He 6 6 3 4 21.0 N H CFR 180.272

2 Aldrin In 1 6 4 6 17.5 Y H CPG 575.100

3 Dieldrin In 1 6 4 6 17.5 Y HH CPG 575.100

4 Chlordane cis Pe 1 6 3 6 15.8 Y HH CPG 575.100

5 Chlordane trans Pe 1 6 3 6 15.8 Y HH CPG 575.100

6 Heptachlor In 1 6 3 6 15.8 Y H CPG 575.100

7 Hexachlorobenzene (HCB) Fu 1 6 3 6 15.8 Y HH CPG 575.100

8 Chlordane Pe 1 6 3 6 15.8 N CPG 575.100

9 Chlordane-alpha-cis Pe 1 6 3 6 15.8 N CPG 575.100

10 Propargite In 6 6 1 4 15.0 N H CFR 180.259

11 Trifluralin He 6 6 2 3 15.0 N H

12 Mancozeb Fu 6 2 3 4 14.0 N CFR 180.176 

13 Terbufos In 6 5 4 1 13.8 N

14 Diuron He 6 3 2 4 13.5 Y L CFR 180.106

15 Propanil He 6 4 2 3 12.5 Y L CFR 180.274

16 Alpha-Hexachlorocyclohexane In 1 4 4 6 12.5 N M

17 Haloxyfop Pe 1 4 4 6 12.5 N

18 Triphenyltin hydroxide Pe 1 4 4 6 12.5 N

19 Chlorothalonil Fu 6 4 1 4 12.5 Y HH CFR 180.275

20 Acetochlor He 6 4 1 4 12.5 N CFR 180.470

21 DDD In 1 6 3 4 12.3 Y H CPG 575.100

22 DDD o,p' In 1 6 3 4 12.3 Y H CPG 575.100

23 DDE o,p' In 1 6 3 4 12.3 Y H CPG 575.100

24 DDD p,p' + DDT o,p' In 1 6 3 4 12.3 Y HH CPG 575.100

25 DDE p,p' In 1 6 3 4 12.3 Y HH CPG 575.100

26 DDT In 1 6 3 4 12.3 Y HH CPG 575.100

27 DDT p,p' In 1 6 3 4 12.3 Y HH CPG 575.100

28 Ethoprop In 3 4 3 4 12.3 N

29 Lactofen He 3 5 2 4 12.0 N

30 Pendimethalin He 6 6 1 3 12.0 N CFR 180.361

31 Permethrin (cis&trans) In 3 6 1 4 11.3 Y HH CFR 180.378

32 Captan Fu 6 3 1 4 11.3 N L CFR 180.103

33 Tetraconazole Fu 2 5 2 4 10.5 Y M CFR 180.557

34 Bromadiolone Pe 1 6 5 1 10.5 N

35 Flocoumafen Pe 1 6 5 1 10.5 N

36 Mirex In 1 6 3 3 10.5 N H CPG 575.100

37 Diclofop methyl He 2 5 2 4 10.5 N

38 Quintozene 

(Pentachloronitrobenzene) Fu 2 5 3 3 10.5 N M

39 Kresoxim-methyl Fu 2 4 3 4 10.5 N CFR 180.554 

40 Benfluralin He 2 6 2 3 10.0 N H
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

41 Bifenthrin In 4 6 1 3 10.0 Y HH CFR 180.442

42 Acifluorfen He 4 4 1 4 10.0 N

43 Dicofol (as dichlorobenzophenone) In 2 6 2 3 10.0 N H

44 Oxyfluorfen He 3 5 2 3 10.0 N M CFR 180.381 

45 Spirodiclofen In 2 6 1 4 10.0 N H CFR 180.608

46 Bromoxynil He 6 4 1 3 10.0 N CFR 180.324

47 MCPA (2-Methyl-4-

chlorophenoxyacetic acid ) He 6 4 3 1 10.0 N CFR 180.339 

48 Propiconazole Fu 6 4 1 3 10.0 Y M CFR 180.434

49 Carbaryl (1-Naphthol) In 5 3 1 4 10.0 Y HH CFR 180.169

50 Ethalfluralin He 4 6 1 3 10.0 N H

51 Fipronil desulfinyl In 1 5 3 3 9.0 Y

52 Fipronil sulfide In 1 5 3 3 9.0 Y

53 Fipronil In 2 4 3 3 9.0 Y HH CFR 180.517

54 Clodinafop-propargyl He 2 4 3 3 9.0 N

55 Dimethenamid He 6 3 1 3 9.0 N

56 Tralkoxydim He 1 5 2 4 9.0 N

57 Tembotrione He 3 3 3 3 9.0 N CFR 180.634

58 Tebuconazole Fu 5 4 1 3 9.0 N CFR 180.474

59 Oxychlordane (chlordane 

byproduct) In 1 6 4 1 8.8 Y HH CPG 575.100

60 Pentachlorobenzene (PCB) Other 1 6 3 2 8.8 Y H

61 Resmethrin (cis& trans) In 1 6 1 4 8.8 Y H

62 Amitraz In 1 6 2 3 8.8 N L CFR 180.287

63 Endrin In 1 6 3 2 8.8 N H

64 Ethiprole Pe 1 6 2 3 8.8 N

65 Tridiphane He 1 6 2 3 8.8 N H

66 Beta-Hexachlorocyclohexane (bHCH) In 1 4 4 3 8.8 N M

67 Acephate In 6 1 2 3 8.8 Y HH CFR 180.108

68 Pyraflufen He 2 5 1 4 8.8 N CFR 180.585

69 Thiodicarb Pe 5 2 1 4 8.8 N

70 Triallate He 2 5 2 3 8.8 N

71 Flumiclorac pentyl Pe 2 5 4 1 8.8 N

72 Chlorpyrifos In 6 5 2 1 8.3 Y HH CFR 180.342

73 Hexythiazox In 2 6 1 3 8.0 Y H CFR 180.448

74 Cypermethrin (all isomers) In 2 6 1 3 8.0 N H CFR 180.418

75 Pyrethrin I Py 2 6 1 3 8.0 N HH CFR 180.128

76 Thiobencarb He 6 4 1 2 7.5 Y L CFR 180.401

77 Profenofos In 1 5 4 1 7.5 Y M CFR 180.404

78 Omethoate (dimethoate byproduct) In 4 1 3 3 7.5 Y L CFR 180.204

79 Imazalil Fu 2 4 1 4 7.5 Y M CFR 180.413 

80 Lindane (gammahexachlorocyclohexane) Pe 1 4 3 3 7.5 Y HH
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

81 Linuron He 2 4 2 3 7.5 Y L CFR 180.184

82 Chlorfenapyr Pe 1 5 2 3 7.5 N

83 Chlorobenzilate Pe 1 5 1 4 7.5 N

84 EPN (Ethyl p-nitrophenyl 

phenylphosphorothioate) Pe 1 5 4 1 7.5 N

85 Fenthion (MPP) In 1 5 4 1 7.5 N M

86 Isofenphos In 1 5 4 1 7.5 N M

87 Oxadiazon He 1 5 2 3 7.5 N M

88 Prochloraz Fu 1 5 2 3 7.5 N

89 Cadusafos In 1 4 5 1 7.5 N

90 Etridiazole Fu 1 4 2 4 7.5 N L

91 Oxythioquinox Pe 1 4 2 4 7.5 N M

92 Disulfoton Pe 1 5 4 1 7.5 N

93 Fluthiacet-Methyl (CGA-248757) Pe 2 3 2 4 7.5 N

94 Isoxaflutole He 3 3 1 4 7.5 N L

95 Ziram Fu 4 2 2 3 7.5 N

96 Nonachlor -cis In 1 6 3 1 7.0 Y H

97 Ethion In 1 6 3 1 7.0 Y H

98 Ethion monoxon In 1 6 3 1 7.0 Y HH

99 Nonachlor -trans In 1 6 3 1 7.0 Y H

100 Piperonyl butoxide Sy 2 5 1 3 7.0 Y HH CFR 180.127

101 Buprofezin In 2 5 1 3 7.0 Y M CFR 180.511

102 Fenoxaprop ethyl He 2 5 1 3 7.0 Y M CFR 180.430

103 Malathion In 4 3 1 3 7.0 Y L CFR 180.111

104 Carbophenothion In 1 6 3 1 7.0 N H

105 Chlorthal dimethyl (DCPA) Pe 2 5 1 3 7.0 N

106 Difenoconazole Fu 2 5 1 3 7.0 Y M CFR 180.475

107 Dinocap Fu 1 6 3 1 7.0 N

108 Methoxychlor In 1 6 2 2 7.0 N H

109 Metrafenone He 2 5 1 3 7.0 N

110 Penthiopyrad Fu 2 5 1 3 7.0 N CFR 180.658

111 Parathion methyl In 1 3 4 3 7.0 N M

112 Phorate (thimet) In 3 4 3 1 7.0 N M

113 Ethephon He 6 1 2 2 7.0 N CFR 180.300

114 Quizalofop ethyl He 2 5 2 2 7.0 N M CFR 180.441

115 Dicrotophos In 3 1 4 3 7.0 N

116 Glufosinate-ammonium He 6 1 3 1 7.0 N CFR 180.473 

117 Simazine He 6 3 2 1 6.8 Y L CFR 180.213

118 Fomesafen He 6 3 2 1 6.8 N

119 2,4-D (2,4-Dichlorophenoxyacetic 

acid) He 6 3 1 2 6.8 N CFR 180.142

120 Cyhalothrin- lambda Py 3 6 2 1 6.8 N

121 Dicamba He 6 3 1 2 6.8 N CFR 180.227
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

122 Tetrachlorvinphos In 1 4 1 4 6.3 Y M CFR 180.252

123 Thiabendazole Fu 2 3 1 4 6.3 Y HH CFR 180.242

124 Dinoseb Fu 1 4 2 3 6.3 N

125 Epoxiconazole Fu 1 4 1 4 6.3 N

126 Iprovalicarb Fu 1 4 1 4 6.3 N

127 Molinate Pe 1 4 2 3 6.3 N

128 Parathion (Parathion-ethyl) In 1 4 2 3 6.3 N M

129 Procymidone Fu 1 4 1 4 6.3 N

130 Terbutryn He 1 4 2 3 6.3 N

131 Tolyfluanid In 1 4 1 4 6.3 N

132 Alachlor He 1 4 1 4 6.3 Y M CFR 180.249

133 Dimethoate In 4 1 2 3 6.3 Y L CFR 180.204

134 Cyproconazole Fu 2 3 1 4 6.3 N CFR 180.485

135 Iprodione Fu 2 3 1 4 6.3 N L CFR 180.399 

136 Triadimenol Fu 1 4 2 3 6.3 N L

137 Pyridaben In 2 6 2 1 6.0 Y H CFR 180.494

138 Diazinon In 2 4 3 1 6.0 Y HH CFR 180.153

139 Tefluthrin In 2 6 2 1 6.0 Y H

140 Metribuzin He 6 2 1 2 6.0 Y L CFR 180.332

141 Boscalid Fu 3 3 1 3 6.0 Y HH CFR 180.589

142 Ethion dioxon In 1 5 3 1 6.0 N H

143 Isoxaben He 2 4 1 3 6.0 N

144 Picoxystrobin Fu 2 4 1 3 6.0 N CFR 180.669

145 Pirimiphos ethyl Pe 1 5 3 1 6.0 N

146 Sulfoxaflor In 2 4 1 3 6.0 N CFR 180.668

147 Tetramethrin In 1 5 1 3 6.0 N M

148 Bicyclopyrone He 2 2 3 3 6.0 N CFR 180.682

149 Flumethrin Py 2 6 2 1 6.0 N

150 Prometryn He 4 4 2 1 6.0 N

151 Clofentezine Pe 2 4 1 3 6.0 N L CFR 180.446

152 Dichlorprop-P He 2 4 3 1 6.0 N

153 Fluazinam Fu 2 4 1 3 6.0 N CFR 180.574

154 Flufenacet He 2 4 3 1 6.0 N L CFR 180.527

155 Fluometuron Fu 3 3 1 3 6.0 N CFR 180.229

156 Pyrimethanil Fu 2 4 1 3 6.0 N CFR 180.518

157 2,4-Db He 4 4 2 1 6.0 N CFR 180.331

158 Chlorpyrifos methyl Pe 1 5 3 1 6.0 Y M CFR 180.419

159 Fenbuconazole Fu 2 4 1 3 6.0 N L CFR 180.480

160 Triclopyr He 5 3 1 2 6.0 N

161 Mesotrione Pe 6 2 2 1 6.0 N

162 Pentachloroaniline (PCA) Other 1 6 2 1 5.3 Y H

163 Sulprofos In 1 6 2 1 5.3 Y H

164 Dimoxystrobin Fu 1 6 2 1 5.3 N
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

165 Fenvalerate (also see Esfenvalerate) In 1 6 2 1 5.3 N H

166 Hydroprene In 1 6 1 2 5.3 N H

167 Phenothrin In 1 6 2 1 5.3 N H

168 Picolinafen Pe 1 6 2 1 5.3 N

169 Tolfenpyrad In 1 6 2 1 5.3 N CFR 180.675

170 Dodine Pe 2 5 2 1 5.3 N

171 Propazine He 3 4 2 1 5.3 N

172 Famoxadone Fu 2 5 2 1 5.3 N M CFR 180.587

173 Fluazifop-p-butyl He 2 5 2 1 5.3 N M CFR 180.411

174 Gamma-Cyhalothrin Py 1 6 2 1 5.3 N CFR 180.438

175 Fludioxonil Fu 2 5 1 2 5.3 N CFR 180.516

176 Paraquat He 6 1 2 1 5.3 N CFR 180.205

177 Metolachlor He 6 4 1 1 5.0 Y L CFR 180.368

178 MGK-264 (isomers 1&2) Sy 1 4 1 3 5.0 Y HH

179 Propetamphos In 1 4 3 1 5.0 Y M

180 Propachlor He 1 3 1 4 5.0 Y L CFR 180.211

181 Norflurazon He 2 3 1 3 5.0 Y L CFR 180.356

182 Heptachlor epoxide (cis&trans) or 

(B+A) In 1 1 4 6 5.0 Y HH CPG 575.100

183 Bromacil Pe 2 3 1 3 5.0 N

184 Chlorfenvinphos In 1 4 3 1 5.0 N M

185 Endrin ketone In 1 4 3 1 5.0 N

186 Fenamiphos In 1 4 3 1 5.0 N L

187 Hexaconazole Fu 1 4 1 3 5.0 N

188 Terbuthylazine He 1 4 2 2 5.0 N

189 Triflusulfuron-methyl Pe 1 4 1 3 5.0 N

190 Vinclozolin Fu 1 4 1 3 5.0 N L

191 Famphur Pe 1 3 4 1 5.0 N

192 Fenthion sulfone In 1 3 4 1 5.0 N M

193 Folpet Pe 1 3 1 4 5.0 N

194 Methidathion In 1 3 2 3 5.0 N L

195 Triadimefon Fu 1 3 2 3 5.0 N L

196 EPTC (S-Ethyl 

dipropylthiocarbamate ) He 6 4 1 1 5.0 N

197 Pyrasulfotole He 2 3 1 3 5.0 N CFR 180.631

198 Clethodim He 5 5 1 1 5.0 N M CFR 180.458

199 Thiacloprid In 2 2 1 4 5.0 N L CFR 180.594

200 Pyraclostrobin Fu 6 4 1 1 5.0 N M CFR 180.582

201 Endosulfan I In 1 5 2 1 4.5 Y HH

202 Primisulfuron He 2 4 2 1 4.5 N CFR 180.452

203 Atrazine He 6 3 1 1 4.5 Y L CFR 180.220

204 Azoxystrobin Fu 6 3 1 1 4.5 N L CFR 180.507

205 Dichlorvos (ddvp) Pe 1 2 3 3 4.5 N L CFR 180.235
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

206 Bitertanol Fu 1 5 2 1 4.5 N

207 Furathiocarb Pe 1 5 2 1 4.5 N

208 Penconazole Fu 1 5 2 1 4.5 N

209 Phenmedipham Pe 2 4 1 2 4.5 N

210 Phosalone In 1 5 2 1 4.5 N M

211 Propaquizafop He 1 5 2 1 4.5 Y

212 Prosulfocarb He 1 5 2 1 4.5 N

213 Triflumuron Pe 1 5 2 1 4.5 N

214 Pirimicarb Other 1 2 2 4 4.5 N

215 Propoxur In 1 2 2 4 4.5 Y

216 Quinclorac He 3 3 1 2 4.5 N CFR 180.463

217 Bentazon He 6 3 1 1 4.5 N CFR 180.355

218 Pymetrozine In 2 1 2 4 4.5 Y

219 Fenpropathrin Py 2 6 1 1 4.0 N H CFR 180.466

220 Pyriproxyfen In 2 6 1 1 4.0 N H

221 Trifloxystrobin Fu 3 5 1 1 4.0 N M CFR 180.555

222 Acequinocyl In 2 6 1 1 4.0 N CFR 180.599

223 Fenazaquin In 2 6 1 1 4.0 Y

224 Etoxazole In 2 6 1 1 4.0 N CFR 180.593

225 Fenbutatin oxide In 2 6 1 1 4.0 N CFR 180.362

226 Fenpyroximate Pe 2 6 1 1 4.0 N H CFR 180.566

227 Florasulam Pe 2 6 1 1 4.0 N

228 Methiocarb In 1 3 2 2 4.0 N L

229 Novaluron He 2 6 1 1 4.0 N H CFR 180.598 

230 Triforin Fu 1 3 1 3 4.0 N

231 Cyhalothrin (all isomers) In 2 6 1 1 4.0 N HH

232 Fluroxypyr He 5 3 1 1 4.0 N L CFR 180.535 

233 Dichlobenil Pe 1 3 1 3 4.0 N

234 ETU (Ethylene thiourea) Pe 1 1 4 4 4.0 N

235 Cyfluthrin (all isomers) In 2 6 1 1 4.0 Y HH CFR 180.436

236 Esfenvalerate In 2 6 1 1 4.0 N H CFR 180.533

237 Phosmet In 1 3 1 3 4.0 N L CFR 180.261

238 Chlorpyrifos oxon In 1 3 3 1 4.0 N

239 Prallethrin In 1 4 1 2 3.8 N M

240 Endosulfan II In 1 4 2 1 3.8 Y HH

241 Endosulfan sulfate In 1 4 2 1 3.8 Y HH

242 Endosulfan Pe 1 4 2 1 3.8 N HH CFR 180.182

243 Ethofumesate He 2 3 1 2 3.8 N L CFR 180.345

244 Ametryn He 2 3 2 1 3.8 Y

245 Azinphos-ethyl In 1 4 2 1 3.8 Y L

246 Chloroxuron He 1 4 2 1 3.8 N

247 Fenitrothion (MEP) In 1 4 2 1 3.8 N L

248 Fluquinconazole Fu 1 4 2 1 3.8 N
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

249 Fpyriproxyfen Fu 1 4 2 1 3.8 N M

250 Paclobutrazol Fu 1 4 1 2 3.8 N

251 Fenarimol Fu 1 4 2 1 3.8 N M

252 Flusilazole Fu 1 4 2 1 3.8 N

253 Naptalam He 1 4 1 2 3.8 N

254 Diquat He 2 3 2 1 3.8 N CFR 180.226

255 Emamectin In 2 1 4 1 3.8 N CFR 180.505

256 Sulfosulfuron He 2 1 1 4 3.8 Y CFR 180.552

257 Metiram Pe 2 1 1 4 3.8 Y

258 Tribenuron methyl Pe 2 1 2 3 3.8 N

259 Indoxacarb In 2 5 1 1 3.5 N M CFR 180.564

260 Tebufenozide In 2 5 1 1 3.5 N M CFR 180.482

261 Methoxyfenozide In 3 4 1 1 3.5 N M CFR 180.544

262 2,6-Diisopropylnaphthalene (2,6-

DIPN) He 1 6 1 1 3.5 N L

263 Beta cyfluthrin Pe 1 6 1 1 3.5 N CFR 180.436

264 Bromophos In 1 6 1 1 3.5 Y

265 Bromopropylate In 1 6 1 1 3.5 N

266 Carbosulfan Other 1 6 1 1 3.5 Y

267 Cloquintocet-mexyl Pe 1 6 1 1 3.5 N

268 Cyhexatin Pe 1 6 1 1 3.5 N

269 Cyphenothrin In 1 6 1 1 3.5 N H

270 Deltamethrin In 2 5 1 1 3.5 N M CFR 180.435

271 Etofenprox In 1 6 1 1 3.5 N CFR 180.620

272 Flucythrinate Py 1 6 1 1 3.5 N

273 Flufenoxuron In 1 6 1 1 3.5 N H CFR 180.623

274 Fluxapyroxad Fu 3 4 1 1 3.5 N CFR 180.666

275 Isoxadifen-ethyl He 1 6 1 1 3.5 Y

276 Mefenpyr-diethyl He 2 5 1 1 3.5 N CFR 180.509 

277 Methoprene In 1 6 1 1 3.5 N H CFR 180.1033

278 Pyridate Pe 1 6 1 1 3.5 N

279 S-methoprene Pe 1 6 1 1 3.5 N CFR 180.368

280 Spiroxamine Pe 1 6 1 1 3.5 N

281 Temephos In 1 6 1 1 3.5 N

282 Tridemorph Fu 1 6 1 1 3.5 N

283 Butralin He 2 5 1 1 3.5 N

284 Cyhalofop-butyl He 2 5 1 1 3.5 Y

285 Fluopicolide Fu 2 5 1 1 3.5 N

286 Fluopyram Fu 2 5 1 1 3.5 N CFR 180.661

287 Flutolanil Fu 3 4 1 1 3.5 N M CFR 180.484

288 Quinoxyfen Pe 2 5 1 1 3.5 N

289 Spiromesifen In 2 5 1 1 3.5 N M CFR 180.607

290 Prothioconazole Fu 3 4 1 1 3.5 N CFR 180.626
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

291 Amitrole He 1 1 3 4 3.5 N

292 Clopyralid He 5 2 1 1 3.5 N CFR 180.431

293 Flumioxazin He 4 3 1 1 3.5 N

294 Glyphosate He 6 1 1 1 3.5 N CFR 180.364 

295 Fluvalinate (τ-Fluvalinate) In 1 5 1 1 3.0 N M

296 Pirimiphos methyl In 1 5 1 1 3.0 N M CFR 180.409

297 Benoxacor He 1 3 2 1 3.0 N L CFR 180.460

298 Diflubenzuron In 2 4 1 1 3.0 N M CFR 180.377

299 Carbofuran In 1 3 2 1 3.0 N L

300 Hexazinone He 2 2 1 2 3.0 N L CFR 180.396

301 Carfentrazone ethyl He 2 4 1 1 3.0 N L CFR 180.515

302 Azinphos methyl In 1 3 2 1 3.0 N L

303 Acibenzolar-S-methyl Fu 2 4 1 1 3.0 N

304 Cyantraniliprole In 2 4 1 1 3.0 N CFR 180.672

305 Desmedipham He 2 4 1 1 3.0 N

306 Didecyldimethylammonium 

chloride Pe 1 5 1 1 3.0 N CFR 180.1317

307 Diflufenican He 1 5 1 1 3.0 N

308 Fenpropimorph Pe 1 5 1 1 3.0 N

309 Propyzamide He 2 4 1 1 3.0 N CFR 180.317

310 Tecnazene Fu 1 5 1 1 3.0 N

311 Tetradifon Pe 1 5 1 1 3.0 N

312 Tolclofos-methyl Fu 1 5 1 1 3.0 N

313 4-chlorophenoxyacetic acid (4-cpa) Pe 1 3 2 1 3.0 N

314 Dichloran Pe 1 3 2 1 3.0 Y

315 Fensulfothion In 1 3 2 1 3.0 Y

316 Guazatine Fu 1 3 2 1 3.0 Y

317 Naled Pe 2 2 2 1 3.0 N

318 Asulam He 2 1 1 3 3.0 N CFR 180.360

319 Bifenazate Other 2 4 1 1 3.0 N L CFR 180.572

320 Carbendazim Fu 1 2 1 3 3.0 N L

321 Clofencet Pe 1 2 1 3 3.0 N

322 Diclosulam Pe 2 4 1 1 3.0 N

323 Fenamiphos sulfone In 1 2 3 1 3.0 N L

324 Fenamiphos sulfoxide In 1 2 3 1 3.0 N L

325 Fenhexamid Fu 2 4 1 1 3.0 Y

326 Ferbam Pe 2 1 1 3 3.0 N

327 Flubendiamide In 2 4 1 1 3.0 N CFR 180.639

328 Formetanate hydrochloride Pe 1 2 3 1 3.0 N

329 Fosthiazate Other 1 2 3 1 3.0 N

330 Ipconazole Fu 1 5 1 1 3.0 N

331 Mandipropamid Fu 2 4 1 1 3.0 N
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

332 MCPB (4-(2-Methyl-4-

chlorophenoxy) butyric acid) He 2 4 1 1 3.0 N

333 Metconazole Fu 2 4 1 1 3.0 Y CFR 180.617

334 Pinoxaden He 2 4 1 1 3.0 N CFR 180.611

335 Prosulfuron He 2 4 1 1 3.0 N

336 Spirotetramat In 2 4 1 1 3.0 N CFR 180.641

337 Chlorantraniliprole In 2 4 1 1 3.0 N CFR 180.628

338 Cyclanilide He 2 2 2 1 3.0 N CFR 180.506

339 Cyprodinil Fu 2 4 1 1 3.0 N CFR 180.532

340 Imazamethabenz-methyl He 2 2 1 2 3.0 N

341 Napropamide He 2 4 1 1 3.0 N

342 Topramezone He 2 2 2 1 3.0 N CFR 180.612

343 Trichlorfon Pe 1 1 3 3 3.0 N CFR 180.198

344 Trifloxysulfuron He 2 2 2 1 3.0 Y

345 Clomazone He 3 3 1 1 3.0 N

346 Flonicamid In 2 1 1 3 3.0 N L CFR 180.613

347 Formetanate Pe 2 1 3 1 3.0 N

348 Oxydemeton methyl In 2 1 3 1 3.0 Y L CFR 180.330

349 Phorate oxon In 1 2 3 1 3.0 N M

350 Phorate sulfone In 1 2 3 1 3.0 N M

351 Phorate sulfoxide In 1 2 3 1 3.0 Y M

352 Pyrithiobac sodium Pe 2 1 1 3 3.0 N

353 Thiram Pe 2 2 2 1 3.0 N

354 Imazethapyr He 3 3 1 1 3.0 N CFR 180.447

355 Fentin hydroxide Fu 2 1 3 1 3.0 N CFR 180.236

356 Maneb Pe 1 1 2 4 3.0 N

357 Thifensulfuron-methyl He 2 2 1 2 3.0 N

358 Abamectin (Avermectin B1) In 2 1 3 1 3.0 N CFR 180.449

359 Atrazine-desethyl He 1 3 2 1 3.0 N

360 Chlorpyrifos-methyl oxon In 1 2 3 1 3.0 N M CFR 180.419

361 Pronamide He 1 4 1 1 2.5 N L

362 Chloroneb Fu 1 4 1 1 2.5 N L

363 Chlorpropham He 1 4 1 1 2.5 N L CFR 180.181

364 Methamidophos In 1 1 4 1 2.5 N L

365 Myclobutanil Fu 2 3 1 1 2.5 Y L CFR 180.443

366 Benalaxyl Pe 1 4 1 1 2.5 N

367 Butafenacil He 1 4 1 1 2.5 Y CFR 180.592

368 Cloransulam-methyl Pe 2 3 1 1 2.5 N

369 Diphenylamine (DPA) Fu 1 4 1 1 2.5 N HH CFR 180.190

370 Ethoxyquin Fu 1 4 1 1 2.5 N

371 Fenamidone Fu 2 3 1 1 2.5 N L CFR 180.579

372 Lenacil He 1 4 1 1 2.5 N

373 Nitrapyrin Other 1 4 1 1 2.5 Y L
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

374 O-Phenylphenol Other 1 4 1 1 2.5 Y

375 Pyroxasulfone Pe 3 2 1 1 2.5 N

376 Tepraloxydim He 1 4 1 1 2.5 Y

377 Triazophos Pe 1 4 1 1 2.5 N

378 Cyazofamid Fu 2 3 1 1 2.5 N

379 Dimethomorph Pe 2 3 1 1 2.5 N

380 Flucarbazone Pe 2 3 1 1 2.5 N

381 Fluoxastrobin Fu 2 3 1 1 2.5 N L CFR 180.609

382 Flutriafol Fu 2 3 1 1 2.5 N CFR 180.629

383 Imazapic-ammonium He 2 3 1 1 2.5 N CFR 180.490

384 Imazaquin He 2 3 1 1 2.5 N

385 Iodosulfuron methyl Pe 1 4 1 1 2.5 N

386 Propoxycarbazone He 2 3 1 1 2.5 N CFR 180.600

387 Triticonazole Fu 1 4 1 1 2.5 N

388 Captan epoxide Pe 1 1 1 4 2.5 Y

389 Daminozide He 1 1 1 4 2.5 N

390 Monocrotophos In 1 1 4 1 2.5 N

391 Phosphine (hydrogen phosphide) Pe 1 1 3 2 2.5 N

392 Propylene oxide Fu 1 1 1 4 2.5 N

393 Chlorimuron-ethyl Pe 2 3 1 1 2.5 N

394 Metsulfuron-methyl He 2 3 1 1 2.5 N CFR 180.428

395 Aldicarb sulfone Other 1 2 2 1 2.3 N L

396 Aldicarb sulfoxide Other 1 2 2 1 2.3 N L

397 Deethylatrazine He 1 2 2 1 2.3 N

398 Aldicarb Other 1 2 2 1 2.3 N L

399 Azamethiphos Pe 1 2 2 1 2.3 Y

400 Bendiocarb Pe 1 2 2 1 2.3 N

401 Cyromazine In 2 1 2 1 2.3 N CFR 180.414

402 Endothall He 1 2 2 1 2.3 N

403 Phosalone oxon Pe 1 2 2 1 2.3 N

404 Imazapyr He 2 1 2 1 2.3 N CFR 180.500 

405 Tebuthiuron He 1 2 1 2 2.3 N L CFR 180.390

406 Aminopyralid He 2 1 1 2 2.3 N CFR 180.610

407 Fluridone He 2 2 1 1 2.0 N L CFR 180.420

408 Fluroxypyr-1-Methylhepyl-Ester He 1 3 1 1 2.0 Y L CFR 180.535 

409 3-Hydroxycarbofuran In 1 1 3 1 2.0 Y L

410 Metalaxyl Fu 2 2 1 1 2.0 N L CFR 180.408

411 Methomyl In 3 1 1 1 2.0 N L

412 Imidacloprid In 3 1 1 1 2.0 N L CFR 180.472 

413 Bupirimate Fu 1 3 1 1 2.0 N

414 Chloroneb, hydroxy- Pe 1 3 1 1 2.0 N

415 Diphenamid He 1 3 1 1 2.0 N L

416 Diphenamid, desmethyl Pe 1 3 1 1 2.0 Y
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

417 Ethoxysulfuron Pe 1 3 1 1 2.0 N

418 Flucarbazone-sodium He 1 3 1 1 2.0 N CFR 180.562

419 Imiprothrin In 1 3 1 1 2.0 N L

420 Prohexadione calcium Fu 2 2 1 1 2.0 Y CFR 180.547

421 Propham He 1 3 1 1 2.0 N L

422 Propoxycarbazone-sodium He 1 3 1 1 2.0 N CFR 180.910

423 Trinexapac ethyl He 2 2 1 1 2.0 N CFR 180.662

424 Bifenthrin, 4'-hydroxy Pe 1 1 1 3 2.0 N

425 Carboxin Pe 1 3 1 1 2.0 Y L CFR 180.301

426 Demeton-S-methyl sulfone In 1 1 3 1 2.0 Y L

427 Dimethipin Pe 1 1 1 3 2.0 Y

428 Mesosulfuron methyl He 2 2 1 1 2.0 N CFR 180.597

429 Phosmet oxon In 1 1 1 3 2.0 N

430 Propamocarb hydrochloride Fu 2 2 1 1 2.0 N

431 Pyroxsulam He 2 2 1 1 2.0 Y

432 Thidiazuron He 2 2 1 1 2.0 N CFR 180.403

433 Thiencarbazone-methyl Pe 2 2 1 1 2.0 N CFR 180.645

434 Triasulfuron He 2 2 1 1 2.0 N CFR 180.459

435 Triflumazole Fu 2 2 1 1 2.0 Y L CFR 180.476

436 Chlorsulfuron He 2 2 1 1 2.0 N CFR 180.405

437 Flumetsulam He 2 2 1 1 2.0 N

438 Saflufenacil He 3 1 1 1 2.0 N CFR 180.649

439 Terbacil He 2 2 1 1 2.0 N L

440 Diflufenzopyr He 2 2 1 1 2.0 N HH

441 Picloram He 3 1 1 1 2.0 N CFR 180.292

442 Sethoxydim He 2 2 1 1 2.0 N L CFR 180.412

443 Malathion oxon In 1 1 1 3 2.0 N L

444 Pyrazon He 1 2 1 1 1.5 N CFR 180.316

445 Clothianidin In 2 1 1 1 1.5 N L

446 Coumaphos S Pe 1 2 1 1 1.5 Y L

447 Thiamethoxam In 2 1 1 1 1.5 N L CFR 180.565

448 Amicarbazone He 1 2 1 1 1.5 N CFR 180.615

449 Carbetamide Pe 1 2 1 1 1.5 N

450 Chloridazon He 1 2 1 1 1.5 Y

451 Coumaphos In 1 2 1 1 1.5 N L CFR 180.189

452 Ethametsulfuron methyl He 1 2 1 1 1.5 N

453 Spinosad In 2 1 1 1 1.5 N CFR 180.495

454 Zineb Fu 1 2 1 1 1.5 N

455 Diquat dibromide He 1 1 2 1 1.5 N CFR 180.226

456 Flupropanate Pe 1 1 2 1 1.5 N

457 Paraquat dichloride He 1 1 2 1 1.5 N CFR 180.205

458 Sulfuryl fluoride Pe 1 1 2 1 1.5 N CFR 180.575

459 Dinotefuran In 2 1 1 1 1.5 N L CFR 180.603
PREDECISIONAL –DRAFT - INTERNAL

Rank Chemicals Type S L H C Score FSIS 

Sampling

EPA 

Rank Authority

460 Fosetyl Fu 2 1 1 1 1.5 N

461 Maleic hydrazide Pe 2 1 1 1 1.5 N

462 Propamocarb Fu 1 2 1 1 1.5 Y

463 Spinetoram In 2 1 1 1 1.5 N CFR 180.635

464 Chlorsulfuron, 5-hydroxy- Pe 1 2 1 1 1.5 N

465 Cymoxanil Fu 2 1 1 1 1.5 N

466 Imazamox He 2 1 1 1 1.5 N CFR 180.1223

467 Oxamyl In 2 1 1 1 1.5 N

468 Halosulfuron-methyl He 2 1 1 1 1.5 Y CFR 180.479

469 Nicosulfuron He 2 1 1 1 1.5 N CFR 180.454

470 Rimsulfuron He 2 1 1 1 1.5 N

471 Coumaphos O Pe 1 1 1 1 1.0 Y L

472 Acetamiprid In 1 1 1 1 1.0 N L CFR 180.578

473 Azimsulfuron He 1 1 1 1 1.0 N

474 Azinphos-methyl oxon In 1 1 1 1 1.0 N L

475 Chlormequat Pe 1 1 1 1 1.0 Y CFR 180.698

476 Dalapon (2,2-dpa) He 1 1 1 1 1.0 N

477 Difenzoquat Pe 1 1 1 1 1.0 N

478 Fosetyl-aluminum Fu 1 1 1 1 1.0 N

479 Glyphosate-Trimethylsulfonium 

(Sulfosate) Pe 1 1 1 1 1.0 N

480 Mepiquat chloride He 1 1 1 1 1.0 N CFR 180.384

481 Piperazine Fu 1 1 1 1 1.0 N

482 Mepiquat He 1 1 1 1 1.0 N

*Chemical type: fungicide “Fun,” insecticide “In,” herbicide “He,” pesticide “Pe,” pyrethroids “Py,” 

synergist “Sy,” other “Ot.”

** Priority list developed with EPA, which summarize pesticide analytes that have been monitored in 

meats and poultry as part of USDA’s Pesticide Data program (PDP). “HH” – highest priority, “H”-high 

priority, “M”-medium priority, L- low priority. 

***Pesticides with EPA-established tolerances on FSIS-regulated products. Regulations are codified 

annually in the U.S. Code of Federal Regulations (CFR). Title 40: Protection of Environment is the section 

of the CFR that deals with EPA's mission of protecting human health and the environment. Action Levels 

for Poisonous or Deleterious Substances in Human Food and Animal Feed are located in the Compliance 

Policy Guide (CPG),” Sec. 575.100