Exhibit 10.36

SECOND AMENDMENT TO LEASE

THIS SECOND AMENDMENT TO LEASE (this "Amendment") is executed as of April 11, 2007, by and between ECI SHERMAN PLAZA LLC, a Delaware limited
liability company ("Landlord"), and HEMACARE CORPORATION, a California corporation ("Tenant").

Recitals

A.    Landlord
and Tenant entered into a Lease Agreement dated February 10, 2006 (the "Original Lease"). Under the terms
of the Original Lease Tenant leases from Landlord the following three (3) spaces in the building located at 15350 Sherman Way, Van Nuys, California (the "Building"):



B.    Landlord
and Tenant entered into a First Amendment to Lease dated as of August 17, 2006 (the "First Amendment").
Under the First Amendment, Landlord and Tenant (i) agreed on the delivery date for the Initial Premises, (ii) changed the Delivery Deadline for the Additional Premises, and
(iii) relocated the Initial Third Floor Premises and the Additional Premises, all as more particularly contained therein. The Original Lease, as amended by the First Amendment, is herein called
the "Lease".

C.    The
Term of the Lease is scheduled to expire on July 31, 2017 (the "Expiration Date").

D.    By
letter dated January 5, 2007 (the "Office Notice Letter") Landlord delivered an "Offer
Notice" in accordance with the provisions of Article 38 of the Original Lease. The Offer Notice offered to lease to Tenant Suite 380 containing approximately
5,735 rentable square feet, and 4,977 usable square feet (the "Expansion Premises") in accordance with the terms contained in such Offer Notice.

E.    Tenant
has agreed to lease the Expansion Premises, and the parties desire to memorialize the terms of the parties' agreement.

NOW,
THEREFORE, in consideration of the foregoing recitals and the mutual covenants contained herein, and for other good and valuable consideration, the receipt and sufficiency of which
are hereby acknowledged, the parties hereto agree that the Lease is amended as follows:

1.Definitions.Except as otherwise expressly provided herein to the contrary, all capitalized terms used in
this Amendment shall have the same meaning given such terms in the Lease.

2.Leasing of Expansion Premises.Commencing on June 1, 2007 (the "Expansion
Premises Commencement Date") and continuing through the entire Term, Landlord leases to Tenant and Tenant leases from Landlord, the Expansion Premises. The Term of the Lease
for the Expansion Premises shall expire on the Expiration Date. The parties agree that for all purposes under this Amendment, the Expansion Premises contains 5,735 rentable square feet and 4,977
usable square feet.

---



3.Base Rent.Tenant shall pay the following Base Rent for the Expansion Premises in accordance with the
provisions of the Original Lease:

Months

Monthly Base RentJune 1, 2007 - May 31, 2008:

$
13,247.85/mo.June 1, 2008 - May 31, 2009:

$
13,764.00/mo.June 1, 2009 - May 31, 2010:

$
14,280.15/mo.June 1, 2010 - May 31, 2011:

$
14,796.30/mo.June 1, 2011 - May 31, 2012:

$
15,369.80/mo.




4.Base Year.The Base Year for the Expansion Premises shall be calendar year 2007.

5.Tenant's Share.Effective on the Expansion Premises Commencement Date, Tenant's Share is hereby changed to be
20.97%.

6.Tenant's Services.Tenant shall provide its own janitorial and waste disposal service for the Expansion
Premises in accordance with the provisions of Section 9.3 of the Original Lease.

7.Condition of Expansion Premises.Tenant has inspected the Expansion Premises and has agreed to take the
Expansion Premises in its current "AS IS" condition, provided that Tenant Improvements in the Expansion Premises shall be constructed in accordance with the provisions of the Construction Rider
attached as Exhibit B to this Amendment.

8.Parking.On the Expansion Premises Commencement Date, in addition to the number of parking spaces provided by
Landlord under the provisions contained in Article 37Parkingin Exhibit D to the Original Lease, Landlord shall provide Tenant
(a) eight (8) reserved tandem parking spaces within four (4) rows of tandem parking adjacent to Tenant's existing tandem parking, and (b) seventeen (17) unassigned
and non-exclusive parking spaces in the Parking Facility.

9.Security Deposit.Concurrent with Tenant's execution of this Amendment, Tenant shall deliver to Landlord
(a) $15,369.80 to be added to the Security Deposit and held by Landlord in accordance with the provisions of Article 4 of the Original Lease, and (b) an amendment to the Letter of
Credit, increasing the Face Amount by $90,000.00 to be held by Landlord in accordance with the provisions of Article 39 of the Original Lease, subject to the L/C Burnoff contained in
Section 39(b) of the Original Lease.

2

---



10.Full Force and Effect; No Other Amendment.The submission of this Amendment for examination does not
constitute an offer or an option for Tenant to lease or use the Expansion Premises. This Amendment shall become effective as a binding agreement only upon execution and delivery of a fully executed
copy by Landlord to Tenant. Except as amended by this Amendment, the Lease has not been amended or modified; and all of the terms and provisions of the Lease, as modified by this Amendment, remain
unmodified and in full force and effect. Landlord and Tenant hereby ratify the Lease, as amended herein. This Amendment contains the entire agreement between Landlord and Tenant regarding the subject
matters contained herein, and except for the Lease supersedes all prior of contemporaneous agreements, understandings, proposals and other representations by or between Landlord and Tenant, whether
written or oral, all of which are merged herein. This Amendment shall
be binding upon and inure to the benefit of the parties hereto and their respective successors and assigns. This Amendment is hereby executed and delivered in multiple counterparts, each of which
shall have the force and effect of an original.

IN
WITNESS WHEREOF, Landlord and Tenant have executed this Amendment as of the day and year first above written.

|LANDLORD:                                                  |  | TENANT:                                      
|---------------------------------------------------------- |  | ---------------------------------------------
|ECI SHERMAN PLAZA LLC,a Delaware limited liability company |  | HEMACARE CORPORATION,a California corporation
|by:                                                        |  | Embarcadero Capital Investors LP,            
|                                                           |  | a Delaware limited partnership,              
|                                                           |  | sole member                                  
|                                                           |  |                                              
|by                                                         |  | Embarcadero Capital Partners LLC,            
|                                                           |  | a Delaware limited liability company,        
|                                                           |  | its sole general partner                     
|                                                           |  |                                              
|                                                           |  | by:                                          
|                                                           |  |                                              
|                                                           |  | by:                                          
|                                                           |  |                                              
|                                                           |  | by:                                          

(For
corporate entities, signature by TWO corporate officers is required: one by (x) the chairman of the board, the president, or any vice president; andthe other by (y) the secretary, any
assistant secretary, the chief financial officer, or any assistant treasurer.)

3

---



EXHIBIT A

ATTACHED TO AND FORMING A PART OF
SECOND AMENDMENT
DATED AS OF APRIL 11, 2007
BETWEEN
ECI SHERMAN PLAZA LLC, AS LANDLORD,
AND
HEMACARE CORPORATION, AS TENANT ("AMENDMENT")

EXPANSION PREMISES

[Floor plan showing location
and configuration of Expansion Premises
to be inserted.]

| |  | INITIALS: |  |       
| |  | --------- |  | ------
| |  | Landlord  |  | /s/ JH
| |  | Tenant    |  | /s/ JI

Exhibit A, Page 1

---



EXHIBIT B

ATTACHED TO AND FORMING A PART OF
SECOND AMENDMENT
DATED AS OF APRIL 11, 2007
BETWEEN
ECI SHERMAN PLAZA LLC, AS LANDLORD,
AND
HEMACARE CORPORATION, AS TENANT ("AMENDMENT")

CONSTRUCTION RIDER

1.Tenant Improvements.Tenant shall, with reasonable diligence through a contractor
(the "Contractor") approved by Landlord pursuant to the provisions of this Section 1, construct and install in the Expansion Premises the
improvements and fixtures provided for in this Construction Rider ("Tenant Improvements"). Tenant hereby designates Bob Chilton as the individual
authorized to act as Tenant's representative with respect to all approvals, directions and authorizations pursuant to this Tenant Work Letter.

Prior
to the contract for the Tenant Improvements being put out to bid, Landlord and Tenant may each add the names of two (2) contractors to the bid list for construction of the
Tenant Improvements. Landlord shall have the reasonable right to review and approve each contractor on the bid list based upon such contractor's qualifications, including (a) quality of work,
(b) creditworthiness, (c) experience, and (d) references. Landlord approves Warner Constructors, Inc. as the Contractor.



2

---





3

---





4

---





2.Ownership of Tenant Improvements.All Tenant Improvements shall become a part of the Expansion Premises,
shall be the property of Landlord and, subject to the provisions of the Lease, shall be surrendered by Tenant with the Expansion Premises, without any compensation to Tenant, at the expiration or
termination of the Lease in accordance with the provisions of the Lease.

| |  | INITIALS: |  |       
| |  | --------- |  | ------
| |  | Landlord  |  | /s/ JH
| |  | Tenant    |  | /s/ JI

5

---



QuickLinks