Exhibit 4.26 



 


CONSULTING
AMENDING AGREEMENT


 


THIS
AGREEMENT made as of Jan 27, 2022


 


BETWEEN:


 


Stephen
Haworth, of the State of Pennsylvania (hereinafter referred to as the "Consultant")


 


OF
THE FIRST PART,


 


-
and -


 


XORTX
Therapeutics Inc., a corporation incorporated under the

laws of British Columbia, Canada (hereinafter referred to as the

"Corporation")


 


OF
THE SECOND PART.


 


THIS
AGREEMENT WITNESSES that in consideration of the covenants and agreements contained herein, the parties hereto agree as follows:


 


WHEREAS
the Corporation and the Consultant (collectively, the "Parties") entered into an Independent Contractor Agreement
dated July 1, 2021 (the "Original Agreement");


 


AND
WHEREAS the Parties wish to amend the Original Agreement and to continue the engagement of the Contractor with the Company
on the terms and conditions set out in the Original Agreement, as amended by this Consulting Amending Agreement;


 


NOW
THEREFORE in consideration of the premises and the mutual covenants herein contained, and other good and valuable consideration,
the Parties hereby covenant and agree as follows:


 


		1.	Term
of Agreement



 


Section
1.02 is replaced entirely with the following language:


 


The
provision of services by the Consultant to the Corporation hereunder shall commence on November 1, 2021 and shall continue for
a period of 12 months and supersedes any prior agreements and will terminate on October 31, 2022, subject to earlier termination
of this Agreement as set forth in Article Five herein.


 


		2.	Change
in Fee



 


Section
2.01 is replaced entirely with the following language:


 


The
Corporation shall pay to the Consultant for the services provided under this Agreement a rate of:


 


-
 $18,750 USD per month to devote 100% of their efforts on behalf of XORTX Therapeutics Inc.


 




     


     


    

 


-
and will be eligible for an additional payment of up to 30% of the total of the contract at the time of the grant of the payment,
subject to the discretion of the compensation committee.


 


		3.	Law
and Jurisdiction



 


All
references to "Ontario" in Sections 6.09 and 6.10 are hereby changed to "Alberta".


 


		4.	Section
2.04 and 5.03



 


Section
2.04 and Section 5.03 are removed entirely.


 


		5.	Other
Terms



 


All
other terms of the Original Agreement remain unchanged.


 


		6.	Legal
Advice and Entire Agreement



 


This
Amending Agreement, together with the Original Agreement, constitutes the entire agreement between the Parties and supersedes
and replaces any prior agreements between the Parties, whether oral or in writing. The Contractor and Principal acknowledge that
they have had the time and opportunity to obtain independent legal advice with respect to the execution of this Amending Agreement
or have waived that opportunity, and that the Contractor and Principal have read, understand, and agree with all of the terms
and conditions contained herein.


 


IN
WITNESS WHEREOF the Parties have executed and delivered this Amending Agreement as of the day and year first written above.


 


	XORTX Therapeutics Inc.	 	On behalf of Stephen Haworth
    and in his personal capacity as Principal
	 	 	 
	per:	 	 
	 	 	 
	/s/ Allen
    Davidoff	 	/s/ Stephen Haworth
	Allen Davidoff, President and CEO	 	Stephen Haworth