Exhibit
31.1





CERTIFICATION





CERTIFICATION
PURSUANT TO RULE 13(a)-14(a)


OF
THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED


AS
ADOPTED PURSUANT TO


SECTION
302 OF THE SARBANES-OXLEY ACT OF 2002





I,
Branislav Vajdic, Ph.D. certify that:





1.I have reviewed this
annual report of NewCardio Inc., on Form 10-K for the year ended
December 31, 2007;




2.Based on my knowledge,
this report does not contain any untrue statement of a material fact or omit to
state a material fact necessary to make the statements made, in light of the
circumstances under which such statements were made, not misleading with respect
to the period covered by this report;




3.Based on my knowledge,
the financial statements, and other financial information included in this
report, fairly present in all material respects the financial condition, results
of operations and cash flows of the registrant as of, and for, the periods
presented in this report;




4.The registrant’s other
certifying officers and I are responsible for establishing and maintaining
disclosure controls and procedures (as defined in Securities Exchange Act of
1934, as amended, Rules 13a-15(e) and 15d-15(e)) and internal control over
financial reporting (as defined in Securities Exchange Act of 1934, as amended,
Rules 13a-15(f) and 15d-15(f)) for the registrant and have:




a)Designed
such disclosure controls and procedures, or caused such disclosure controls and
procedures to be designed under our supervision, to ensure that material
information relating to the registrant, including its consolidated subsidiaries,
is made known to us by others within those entities, particularly during the
period in which this report is being prepare d;




b)Designed
such internal control over financial reporting, or caused such internal control
over financial reporting to be designed under supervision, to provide reasonable
assurance regarding the reliability of financial reporting and the preparation
of financial statements for external purposes in accordance with generally
accepted accounting principles;




c)Evaluated
the effectiveness of the registrant’s disclosure controls and procedures and
presented in this report our conclusions about the effectiveness of the
disclosure controls and procedures, as of the end of the period covered by this
report based on such evaluation; and




d)Disclosed
in this report any change in the registrant’s internal control over financial
reporting that occurred during the registrant’s most recent fiscal quarter that
has materially affected, or is reasonably likely to materially affect, the
registrant’s internal control over financial reporting;
and




5.The registrant’s other
certifying officer(s) and I have disclosed, based on our most recent evaluation
of internal control over financial reporting, to the registrant’s auditors and
the registrant’s board of directors (or persons performing the equivalent
functions):




a)All
significant deficiencies and material weaknesses in the design or operation of
internal control over financial reporting which are reasonably likely to
adversely affect the registrant’s ability to record, process, summarize and
report financial information; and




b)Any
fraud, whether or not material, that involves management or other employees who
have a significant role in the registrant’s internal control over financial
reporting.




Date:
March 31, 2008




/s/  Branislav
      Vajdic, Ph.D.Branislav
      Vajdic, Ph.D.President
      and Chief Executive Officer