EX-10.1




 Exhibit 10.1 

Tyme Technologies, Inc. 

Nonqualified Stock Option Agreement 

Tyme Technologies, Inc., a Delaware corporation (the “Company”), pursuant to the Company’s 2015 Equity Incentive Plan
(the “Plan”), has granted to ###PARTICIPANT_NAME### (the “Optionee”) a nonqualified stock option (the “Option”) to purchase a total of ###TOTAL_AWARDS### shares (each, a “Share”) of
the common stock, par value $0.0001 per share (the “Common Stock”), of the Company, at the exercise price of ###GRANT_PRICE### per Share (the “Exercise Price”), on the terms and conditions set forth in this
Nonqualified Stock Option Plan Agreement (this “Agreement”) and, in all respects, subject to the terms and conditions of the Plan. The date of grant of the Option is ###GRANT_DATE### (the “Date of Grant”). The
Option is not intended to qualify as an incentive stock option under Section 422 of the Code. Capitalized terms not otherwise defined in this Agreement shall have the meanings assigned to such terms in the Plan. 

1. Duration. Subject to the earlier termination as provided in this Agreement or under the Plan, the Option shall expire and shall no longer be
exercisable as of the close of business on ###EXPIRY_DATE### (the “Expiration Date”). 
  

	2.	 Anti Dilution Provisions. 



(a) If there is any stock dividend, stock split or combination of Shares or other change in capital structure of the Company described in
Section 4.4 of the Plan, the number and amount of Shares then subject to the Option and the Exercise Price shall be proportionately and appropriately adjusted as determined by the Committee, whose determination shall be final, conclusive and
binding upon Optionee and the Company. 
 (b) If there is any other change in the Common Stock, including a reorganization, sale or exchange
of assets, exchange of shares, offering of subscription rights, or a merger, consolidation or similar transaction in which the Company is the surviving corporation, an adjustment, if any, shall be made in the Shares then subject to the Option and
the Exercise Price as the Board or Committee may deem equitable, and whose determination shall be final, conclusive and binding upon Optionee and the Company. Failure of the Board or the Committee to provide for an adjustment pursuant to this
paragraph 2(b) prior to the effective date of any Company action referred to in this paragraph 2(b) shall be conclusive evidence that no adjustment is required in consequence of such action. 

(c) If the Company is merged into or consolidated with any other corporation and the Company is not the surviving corporation, or if the
Company sells all or substantially all of the Company’s assets to any other corporation, then either: 
 (i) the Company
shall cause provisions to be made for the continuance of the Option after such event or for the substitution for the Option of an option covering the number and class of securities which the Optionee would have been entitled to receive in such
merger, consolidation or if the Optionee had been the holder of record of a number of Shares equal to the number of Shares covered by the unexercised portion of the Option immediately prior to such merger, consolidation or sale; or 











 (ii) the Company shall give to Optionee written notice of the Company’s
election not to cause such provision to be made and the Option shall become exercisable in full (or, at the election of the Optionee, in part) at any time during a period of thirty days, to be designated by the Company, ending not more than ten days
prior to the effective date of the merger, consolidation or sale, in which case the Option shall not be exercisable to any extent after the expiration of such thirty -day period; provided, however, that this paragraph 2(c)(ii) shall not apply
in the case of a material transaction resulting from the Company’s strategic evaluation process announced on March 29, 2022. 

Notwithstanding the provisions of this paragraph 2(c), in no event shall the Option be exercisable after the Expiration Date. 

3. Non -Transferability. The Option shall not be transferable by Optionee, other than by (x) will, the laws of descent or
distribution or (y) pursuant to a proceeding under Title 11 of the U.S. Bankruptcy Code or similar insolvency proceeding, and is exercisable during the lifetime of Optionee only by Optionee, except as otherwise specifically provided in this
Agreement or the Plan. The terms of this Agreement shall be binding upon the executors, administrators, heirs, successors and assigns of Optionee. 
 4.
Certain Rights Not Conferred by Option. Optionee shall not, by virtue of holding the Option, be entitled to any rights of a stockholder in the Company. 

5. Expenses. The Company shall pay all original issue and transfer taxes with respect to the issuance of the Shares pursuant hereto and all other fees
and expenses necessarily incurred by the Company in connection therewith. 
  

	6.	 Exercise of Options. 



(a) Subject to paragraphs 6(b) and 6(i) of this Agreement, the Option shall become exercisable on the dates and in the amounts as follows: 

###VEST_SCHEDULE_TABLE### 
 Notwithstanding the
foregoing, unless otherwise determined by the Board, in the event of a material transaction resulting from the Company’s strategic evaluation process announced on March 29, 2022 while Optionee is in the employ or a consultant of the
Company, the Option, to the extent unvested and unexercisable, shall fully vest and become exercisable as of immediately prior to the closing of such transaction. 

(b) In the event of a Change of Control while Optionee is in the employ or a consultant of the Company, the Option, to the extent unvested and
unexercisable, shall fully vest and become exercisable as of immediately prior to such Change of Control. 
 (c) The Option shall be
exercisable, in whole or part and from time to time, but subject to the exercise schedule set forth in paragraph 6(a) of this Agreement, by written or electronic notice to the Chief Executive Officer or Secretary of the Company of such exercise,
complying with the Plan and applicable procedures established by the Committee or the Company. Such notice shall specify the number of Shares for which the Option is being exercised (which number, if less than all of the Shares then subject to
exercise, shall be 100 or an integral multiple thereof) and shall be accompanied by: 

  
 2 












 (i) payment of the full exercise price for the Shares for which the Option
is being exercised; and 
 (ii) this Agreement. 

(d) The form of payment of the Exercise Price for Shares purchased pursuant to each exercise of the Option shall be paid in full at the time of
each purchase in one or a combination of the following methods: 
 (i) cash; 

(ii) check (subject to collection); 

(iii) in the discretion of the Committee, surrender to the Company of other Shares owned by the Optionee, which: 

(A) have a Fair Market Value on the date of surrender equal to the aggregate exercise price of the Shares as to which the
Option is being exercised; and 
 (B) have been owned of record by Optionee for at least six months; 

(iv) by “net exercise,” by means of exercising the Option, to the extent exercisable, and receiving such number of
Shares having a Fair Market Value on the date of such net exercise equal to the difference between: 
 (A) the Fair Market
Value of the full number of Shares issuable upon exercise of the Option on the date of such net exercise; and 
 (B) the
Exercise Price multiplied by the full number of Shares issuable upon exercise of the Option; or 
 (v) if there is a public
market for Shares, subject to applicable law, by: 
 (A) assignment to the Company of the net proceeds (to the extent
necessary to pay such exercise price) to be received from a registered broker upon the sale of the Shares or assignment of the net proceeds (to the extent necessary to pay such exercise price) of a loan from such broker in such amount; or 

(B) such other consideration and method of payment for the issuance of stock to the extent permitted under applicable law and
satisfying the requirements of Rule 16b -3 promulgated pursuant to the Exchange Act. 

  
 3 












 (e) No Shares shall be delivered upon exercise of the Option until all laws, rules and
regulations which the Committee may, in its sole discretion, deem applicable have been complied with. If a registration statement under the Securities Act is not then in effect with respect to the Shares issuable upon such exercise, the Company may
require as a condition precedent that Optionee, upon exercising the Option, deliver to the Company a written representation and undertaking, satisfactory in form and substance to the Committee, that, among other things, Optionee is acquiring the
Shares for Optionee’s own account for investment purposes only and not with a view to the distribution thereof. 
 (f) Optionee shall
not be considered a record holder of the Shares so purchased for any purpose until the date on which Optionee is actually recorded as the holder of such Shares in the records of the Company. 

(g) Notwithstanding Section 5.7(a) of the Plan, if the Optionee is Terminated for any reason except death, Disability, or for Cause, then
the Optionee may exercise the Option (i) only to the extent that the Option would have been exercisable on the Termination Date (after taking into account any acceleration under this Agreement, the Plan and/or the Optionee’s employment
agreement), and (ii) no later than twenty-four months after the Termination Date (or such longer period not exceeding five years as may be determined by the Committee), but in any event, no later than the Expiration Date. 

(h) Subject to paragraphs 6(g) and 6(i) of this Agreement, in the event of Optionee’s death, disability or termination of employment, the
exercisability of the Option shall be governed by the provisions of Section 5.7 of the Plan, unless such provisions are waived by the Committee, in the Committee’s sole discretion. 

(i) Notwithstanding anything in this Agreement to the contrary and for the avoidance of doubt, to the extent that the Optionee has entered into
an employment agreement with the Company that provides for vesting and/or exercise terms that are more favorable than the vesting or exercise terms set forth in this Agreement or the Plan, such more favorable vesting and/or exercise terms shall
apply. 
 7. Withholding of Tax. To the extent that the exercise of the Option, or any event pursuant to this Agreement, results in the incurrence of
compensation or other taxable income by Optionee that is subject to withholding by the Company, Optionee must satisfy such tax withholding obligation by giving written notice to the Company, prior to the delivery of Shares, of the Optionee’s
election to either (a) deliver to the Company an amount of cash equal to the tax withholding amount required under applicable tax laws or regulations or (b) have the Company deduct from the number of Shares that would have otherwise been
delivered to Optionee a number of such Shares having a Fair Market Value equal to such tax withholding amount. Regardless of any action of the Company, Optionee acknowledges that Optionee is ultimately liable for such tax withholding obligation. The
Company shall not be required to deliver any Shares in respect of the Option under this Agreement until such liability is satisfied. 
 8. Continued
Employment or Consultancy. Nothing herein shall be deemed to create any employment or consultancy or guaranty of continued employment or consultancy or limit in any way the Company’s right to terminate Optionee’s employment or
consultancy at any time. 

  
 4 












 9. Investment Representation and Legend of Certificates. Optionee acknowledges that, for any period
in which a registration statement with respect to the Option and/or Shares under the Securities Act of 1933, as amended (the “Securities Act”), is not effective, Optionee shall hold the Option and will purchase and/or own the Shares
for investment purposes only and not for resale or distribution. The Company shall have the right to place upon the face and/or reverse side of any stock certificate or certificates evidencing the Shares such legend as the Committee may prescribe
for the purpose of preventing disposition of such Shares in violation of the Securities Act. 
  

			
	Tyme Technologies, Inc.
		
	By:	 	 /s/ Richard Cunningham

		 	Richard Cunningham
		 	Chief Executive Officer



  
 5 












 OPTIONEE ACKNOWLEDGEMENT 

OPTIONEE ACKNOWLEDGES AND AGREES THAT, EXCEPT AS SET FORTH IN THIS AGREEMENT OR OPTIONEE’S EMPLOYMENT OR CONSULTANCY AGREEMENT, THE
EXERCISABILITY OF THE SHARES SUBJECT TO THIS AGREEMENT AND THE OPTION IS EARNED ONLY BY CONTINUING EMPLOYMENT OR CONSULTANCY AT THE WILL OF THE COMPANY (NOT THROUGH THE ACT OF BEING HIRED, BEING GRANTED THE OPTION OR ACQUIRING SHARES HEREUNDER).
OPTIONEE FURTHER ACKNOWLEDGES AND CONFIRMS THAT NOTHING IN THIS AGREEMENT, NOR IN THE PLAN WHICH IS INCORPORATED HEREIN BY REFERENCE, SHALL CONFER UPON OPTIONEE ANY RIGHT WITH RESPECT TO CONTINUATION OF EMPLOYMENT OR CONSULTANCY BY THE COMPANY, NOR
SHALL IT INTERFERE IN ANY WAY WITH OPTIONEE’S OR THE COMPANY’S RIGHT, SUBJECT TO OPTIONEE’S AND THE COMPANY’S RIGHTS UNDER OTHER AGREEMENTS, IF ANY, WITH THE COMPANY, TO TERMINATE EMPLOYMENT OR CONSULTANCY AT ANY TIME, WITH OR
WITHOUT CAUSE. 
 Optionee acknowledges receipt of a copy of the Plan and certain information related to the Plan and the Company and
represents that Optionee is familiar with the terms and provisions of the Plan, and hereby accepts the Option subject to all of the terms and provisions of the Plan. Optionee has reviewed the Plan and this Agreement in their entirety, has had an
opportunity to obtain the advice of counsel prior to executing this Agreement and fully understands all of the terms and provisions of the Option and this Agreement. Optionee hereby agrees to accept as binding, conclusive and final all decisions or
interpretations of the Committee upon any questions arising under the Plan. Optionee further agrees to notify the Company upon any change in the residence address currently set forth in the Company’s records. 

Accepted and agreed as of 
 the date as first set forth
above: 
 Name: ###PARTICIPANT_NAME### 

  
 6