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| ·   | using the components and excipients identified in Exhibit I, and |
|--------------------|------------------------------------------------------------------|

| ·   | in accordance with the Pricing Schedule identified in Exhibit II. |
|--------------------|-------------------------------------------------------------------|

| General Information                      |
|------------------------------------------|
| Product Name                             | Kevetrin |
| Product use and/or indication            | Oncology |
| Molecule Type                            | Small Molecule |
| Batch Size (# of vials)                  | <3,500 Vials |
| Formulation                              | 30.0 mg/mL |
| Fill volume:                             | 1.0mL |
| Clinical Phase of Lot to be Manufactured | Phase I |
| Countries in which studies will be held  | USA |
| Bulk Drug Substance Storage Conditions   | CRT |
| Drug Product Storage Conditions          | 2-8°C |

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|  Exhibit I: Components, Excipients & Reagents  |
|--------------------------------------------------------------|
| Components                                                   |
| Vials                                                        |
| Type                                                         | Size / Neck Size | Mfg. & Part # | Supplied / Released by |
| Type 1 Glass                                                 | 2mL / 13mm |  TBD | Formatech |
| Stoppers                                                     |
| Style                                                        | Formulation / Coating | Mfg. & Part # | Supplied / Released by |
| Lyo                                                          | FluroTec | West; TBD | Formatech |
| Aluminum Seals                                               |
| Style                                                        | Color | Mfg. & Part # | Supplied / Released by |
| 13mm flip-off crimp seals                                    | TBD | TBD |  Formatech |
| Sterile Filters                                              |
| Mfg.                                                         | Type | Part # | Supplied / Released by |
| TBD                                                          | TBD | TBD | Formatech |
| Excipients & Reagents                                    |
| Description                                                  | Grade | Mfg. & Part # | Supplied / Released by |
| API is formulated in WFI only.                               |

| Exhibit II: MANUFACTURING SERVICES                                                                                                                                                                                   |
|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| Activity                                                                                                                                                                                                             | Pricing | Notes |
| Disposable Manufacturing Equipment· Glass Formulation & Filling Vessels, filling assemblies, sterilizing filters                                                                                  |  $ |    |
| Batch Record Development & Issuance                                                                                                                                                                              | $ |   |
| Cleaning Qualification Study & Initial Cleaning Verification of Manufacturing Equipment                                                                                                                     |   | Verified using TOC Note: additional charges will be incurred if an alternate detection method is required i.e. RP-HPLC |
| Formulation:·Formulation suite usage·Continuous sparging with inert gas·Other special services (UF/DF, etc.)                                                                                     |  Incl.N/AN/A |      |
| Aseptic Manufacturing:·Liquid Filling: ≤3,500  vials(1 day process)·Overtime charges, GMP suite·Lyophilization: ≤48 hours·Nitrogen gas overlay·Other special services |  $ TBD$N/AN/A  |  Note: Formulation & filling in GMP suite not to exceed 8 continuous hours. If filtering/fill time is extended, the following overtime rates will apply:· 1-4 hours: $/hour· Over 4 hours: $/hour· Additional day: $/day  |
| Label Production and Drug Product Labeling                                                                                                                                                                           | TBD |  Vial labeling required  Box labels required Inkjet lot # on overseal |
| Bulk packaging                                                                                                                                                                                                  | Included | Bulk pack into tamper-evident containers per Formatech SOP. |
| Shipping                                                                                                                                                                                                             | TBD* | *Shipping and handling will be billed back to CLIENT separately  |
| Total Cost of Manufacturing Services:             $ + TBD                                                                                           |

| Exhibit II (cont.): ANALYTICAL SERVICES                                                                                                                                                                                                                                                        |
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| Activity                                                                                                                                                                                                                                                                                       | Pricing | Notes |
|   Bulk Drug Substance ID                                                                                                                                                                                                                                                             |
| Note: ID test material must be delivered to Formatech in a satellite container accompanying the API                                                                                                                                                                                       | TBD |   |
|  Bulk Formulated Drug / In-process Testing                                                                                                                                                                                                                                                |
| Density                                                                                                                                                                                                                                                                                        | $ |   |
| Bioburden (includes preparatory test)                                                                                                                                                                                                                                                          | $ | Upon completion of the preparatory test,  the cost of this assay is $ for each subsequent fill |
|  Sterile Filtered Bulk Drug                                                                                                                                                                                                                                                               |
| Bulk Sterility by membrane filtration                                                                                                                                                                                                                                                          | *** | *** Outsourced – costs to be billed back to client. |
|  Drug Product Release Testing                                                                                                                                                                                                                                                             |
| pH (3 samples)                                                                                                                                                                                                                                                                                 | $ |   |
| Osmolality (3 samples)                                                                                                                                                                                                                                                                         | $ |   |
| Appearance (3 samples)                                                                                                                                                                                                                                                                         | $ |   |
| Karl Fischer, Moisture Content (3 samples)                                                                                                                                                                                                                                                     | $ |   |
| Particulate Analysis (USP<788>)                                                                                                                                                                                                                                                          | *** | *** Outsourced – costs to be billed back to client. |
| Sterility (and Bacteriostasis & Fungistasis if required)                                                                                                                                                                                                                                   | *** | *** Outsourced – costs to be billed back to client. |
| Bacterial Endotoxin (and inhibition & Enhancement if required)                                                                                                                                                                                                                             | *** | *** Outsourced – costs to be billed back to client. |
| Total Cost of Analytical Services:                   $+ TBD & ***                                                                                                                      |
|                                                                                                                                                                                                                                                                                           |
|  Final Project Cost:                                        $ USD + TBD & *** |
|                                                                                                                                                                                                                                                                                           |

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