Exhibit 10.1

                                    SUBLEASE

1.       PARTIES

         This Sublease,  dated April 18, 2005 is made between Thomas Group, Inc.
         ("Sublessor"),    a   Delaware   Corporation   and   IPIX   Corporation
         ("Sublessee"), a Delaware Corporation.

2.       MASTER LEASE

         Sublessor is the lessee under a written lease dated February 15th 2000,
         wherein REC  Partners,  L.P.,  ("Lessor")  leased to Sublessor  certain
         space within the building  located on the real property  located in the
         City of Reston, State of Virginia, described as 12120 Sunset Hills Road
         consisting of  approximately  12,027 rentable square feet on the fourth
         (4th) floor. The said lease and any amendments are herein  collectively
         referred to as the "Master  Lease" and are attached  hereto as "Exhibit
         A."  Sublessor  covenants  and agrees that it will not amend the Master
         Lease without further notification to, and prior consent of, Sublessee.

3.       PREMISES

         Sublessor hereby subleases to Sublessee on the terms and conditions set
         forth in this Sublease the Premises  ("Premises")  consisting of 12,027
         rentable square feet on the 4th floor  designated on the attached floor
         plan ("Exhibit B").

4.       WARRANTY BY SUBLESSOR

         Sublessor  warrants and  represents to Sublessee  that the Master Lease
         has not been  amended  or  modified  except as  expressly  set forth in
         Exhibit A herein, that Sublessor is not now, and as of the commencement
         of the Term  hereof  will not be,  in  default  or breach of any of the
         provisions of the Master Lease,  and that Sublessor has no knowledge of
         any claim by Lessor  that  Sublessor  is in default or breach of any of
         the provisions of the Master Lease.

5.       TERM

         The  Term  of  this  Sublease   shall   commence  on  April  15,  2005,
         (hereinafter  "Commencement  Date")  or the date  upon  which  Landlord
         consents to this  Sublease,  whichever  shall first  occur,  and end on
         October 30, 2007  (hereinafter  "Termination  Date")  unless  otherwise
         sooner  terminated in accordance  with the provisions of this Sublease.
         In the event the Term  commences on a date other than the  Commencement
         Date,  Sublessor and Sublessee shall execute a memorandum setting forth
         the actual date of commencement of the Term.  However,  the termination
         date shall remain October 30, 2007.

6.       BASE RENT

         Sublessee  shall pay  monthly  rent to  Sublessor,  without  deduction,
         set-off, notice, or demand, at:

                           The Thomas Group
                           Williams Square - Las Colinas
                           5221 North O'Connor Blvd.
                           Suite 500
                           Irving, TX 75039
                           Attn:  David English

         Or, at such other place as Sublessor  shall designate from time to time
         by notice to Sublessee.  Sublessee shall pay the following (which shall
         entitle Sublessee to occupancy of the premises,  services and utilities
         and all other benefits of the Master Lease):

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         Months 1-12:    $24.75 per rentable square foot per year, full service,
                         (1st 2 months abated),
         Months 13-24:   $25.49 per rentable square foot per year full service,

         Months 25-31:   $26.25 per rentable square foot per year full service,

         in twelve (12) equal  installments  payable in advance on the first day
         of each  month of the Term.  If the Term  begins or ends on a day other
         than the first or last day of a month,  the rent for the partial months
         shall be prorated on a per diem basis.  Unpaid rent shall bear interest
         until paid at the prime rate of interest plus two percent (2%).

7.       OPERATING EXPENSE INCREASES AND REAL ESTATE TAXES

         Sublessee will be responsible  for any increases in operating  expenses
         and real estate  taxes that are billed by the Landlord to, and paid by,
         the  Sublessor  over a 2005 base year.  Beginning on April 15th of 2006
         and occurring every April 15th throughout the Sublease term,  Sublessee
         will pay as additional  rent to Sublessor,  the estimated  increases in
         operating  expenses  and real  estate  taxes over the  previous  year's
         amount for  operating  expenses and real estate taxes,  which  estimate
         will be provided by the Landlord.  Once Landlord has provided Sublessor
         with the actual  expenses for the previous year,  the following  year's
         payments for  estimates  will be  increased  or decreased  accordingly,
         depending on the amount that Sublessee paid for estimates that was more
         or less than the  actual  expenses  for the year those  estimates  were
         paid.

8.       TENANT IMPROVEMENTS

         Sublessee  will  have the  right to make  improvements  to the space at
         Sublessees  sole  expense,  provided  such  improvements  are  made  in
         accordance  with the Master Lease.  Sublessee will be  responsible  for
         obtaining the proper  approval  from the Landlord  regarding the design
         and construction and abiding by the Landlord's  policies and procedures
         regarding construction of tenant improvements and move-in.

9.       SECURITY DEPOSIT

         Sublessee  shall deposit with Sublessor upon execution of this Sublease
         the sum of Ninety  Nine  Thousand  Two  Hundred  Twenty Two Dollars and
         Seventy-Six  cents  ($99,222.76)  in the  form  of  cash  or  check  in
         immediately  available  funds  as a  security  deposit  (the  "Security
         Deposit").  The Security  Deposit  shall be  considered as security for
         Sublessee's faithful performance of Sublessee's  obligations hereunder.
         In addition,  at the time of  execution  Sublessee  shall  deposit with
         Sublessor  the first month's rent in the amount of Twenty Four Thousand
         Eight  Hundred Five Dollars and  Sixty-Nine  cents  ($24,805.69)  to be
         applied  toward  rent for the  period  April  15,  2005-May  15,  2005.
         Sublessor  further agrees to apply the Security Deposit for the monthly
         rent  payments  owed for the last  three (3) months of the term of this
         Sublease.  If  Sublessee  fails to pay Rent or other  charges  when due
         under this Sublease,  or fails to perform any of its other  obligations
         hereunder,  Sublessor  may  use or  apply  all or  any  portion  of the
         Security Deposit, without prejudice to any other remedy which Sublessor
         may  have,  for the  payment  of any  Rent or  other  amount  then  due
         hereunder  and  unpaid,  for the  payment  of any  other  sum for which
         Sublessor  may become  obligated  by reason of  Sublessee's  default or
         breach, or for any loss or damage sustained by Sublessor as a result of
         Sublessee's  default or breach. If Sublessor so uses any portion of the
         Security Deposit,  Sublessee shall, within ten (10) business days after
         written demand by Sublessor,  restore the Security  Deposit to the full
         amount  originally  deposited,  and Sublessee's  failure to do so shall
         constitute  a  default  under  this  Sublease.  Sublessor  shall not be
         required  to keep  the  Security  Deposit  separate  from  its  general
         accounts,  and shall have no  obligation  or  liability  for payment of
         interest on the Security  Deposit.  In the event  Sublessor  assigns or
         otherwise  conveys  its  interest  in this  Sublease,  Sublessor  shall
         deliver to its assignee so much of the Security Deposit as is then held
         by Sublessor  and,  provided that  Sublessor has in fact  delivered the
         Security Deposit as aforesaid,  Sublessee agrees to look solely to such
         grantee or assignee for  application or return of the Security  Deposit

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         from  any  mortgage  or any  purchaser  of  Sublessor's  interest  at a
         foreclosure  sale of any  grantee  of a deed  in  lieu of  foreclosure.
         Within  thirty  (30)  business  days  after  the Term has  expired,  or
         Sublessee has vacated the  Premises,  whichever  shall last occur,  and
         provided  Sublessee  is not then in default  of any of its  obligations
         hereunder,  the  Security  Deposit,  or so much thereof as had not been
         applied by  Sublessor,  shall be returned to  Sublessee  or to the last
         assignee, if any, of Sublessee's interest hereunder.

10.      LATE CHARGES

         Other remedies for nonpayment of rental notwithstanding, time is of the
         essence of this Sublease;  and if Sublessor elects to accept rent on or
         after the sixth  (6th) day of the month,  a late  charge of One Hundred
         Dollars  ($100.00) will be due as additional rent.  Sublessee agrees to
         tender all late rents by cashier's  check,  certified  check,  or money
         order. In the event  Sublessee's  rent check is dishonored by the bank,
         Sublessee  agrees to pay Sublessor  $25.00 as a handling charge and, if
         applicable,  the late  charge.  Dishonored  checks  must be replaced by
         cashier's check, certified check or money order. In the event more than
         one check is dishonored,  Sublessee  agrees to pay all future rents and
         charges  in the form of  cashier's  check,  certified  check,  or money
         order. Any other amounts payable to Sublessor under this Sublease, with
         the  exception  of rent,  shall  be  considered  past due 30 days  from
         Sublessor's billing date; and Sublessee shall pay interest on such past
         due amount  until paid at the prime rate of  interest  plus two percent
         (2%).  The  parties  agree  that  such  charges  represent  a fair  and
         reasonable  estimate of the costs the Sublessor will incur by reason of
         such late payment and/or returned check.

11.      ASSIGNMENT AND SUBLETTING

         Sublessee shall not mortgage,  encumber,  assign, convey or sublet this
         Sublease  or  any  interest   thereunder  in  any  manner  which  would
         constitute  a breach or  violation  of the Master Lease and without the
         prior  written  consent of Sublessor,  which shall not be  unreasonably
         withheld,  and the prior written  consent of Lessor,  as required under
         the terms of the Master Lease.

12.      OTHER PROVISIONS OF SUBLEASE

         All terms and conditions of the Master Lease are incorporated  into and
         made part of this Sublease as if Sublessor were the lessor  thereunder,
         Sublessee were the Lessee thereunder,  and the Premises were the Master
         Premises thereunder.

         Except  for  the  payment  of  rent  thereunder,  giving  notice  to or
         otherwise  communicating  with Lessor and as  otherwise  noted  herein,
         Sublessee  shall  perform and observe  all the  agreements,  covenants,
         conditions  and  provisions  to be performed  and observed by Sublessor
         under the Master Lease as and when  performance  and  observance is due
         and that the Lessor under the Master Lease or the  Sublessor  will have
         the  right  to  enforce  such  agreements,  covenants,  conditions  and
         provisions  directly against Sublessee.  Sublessee shall not commit or,
         to the extent within its responsibilities  under this Sublease,  suffer
         any act or  omission  that will  violate any of the  provisions  of the
         Master Lease.  Sublessor  shall exercise due diligence in attempting to
         cause Lessor to perform its obligations  under the Master Lease for the
         benefit of Sublessee.

         The failure of Lessor to perform its  covenants  under the Master Lease
         shall not allow  Sublessee  to  withhold,  set-off or abate any rent or
         other amounts due hereunder;  further,  in no event shall  Sublessor be
         liable to Sublessee for any damages,  costs or expenses which Sublessee
         may incur by reason of Lessor's  failure to perform its covenants under
         the Master Lease,  provided that in either case Sublessor has exercised
         due diligence in attempting to cause Lessor to perform its obligations.

         If the Master Lease  terminates,  this Sublease shall terminate and the
         parties shall be relieved of any future  liability or obligation  under
         this Sublease, provided however, that if the Master Lease terminates as
         a result of a default or breach by Sublessor  or  Sublessee  under this
         Sublease  and/or the Master Lease,  then the defaulting  party shall be
         liable to the non-defaulting  party for the damage suffered as a result
         of such termination.

         If the Master Lease gives  Sublessor  any right to terminate the Master
         Lease at  Sublessor's  option,  Sublessor will not terminate the Master

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         Lease without the expressed  written  consent of the Sublessee.  If the
         Master  Lease gives  Sublessor  any right to renew the Master  Lease at
         Sublessor's option,  Sublessee shall have no right to require Sublessor
         to renew the Master  Lease.  If the Master  Lease gives  Sublessor  the
         right  of  first  offer,  Sublessee  shall  have no  right  to  require
         Sublessor to exercise the right of first offer.

         Sublessee  shall  have  use  of  Sublessor's  remaining  furniture  and
         fixtures (the "Equipment").  Sublessee shall, at its own expense,  keep
         the  Equipment in good working  order and repair,  reasonable  wear and
         tear and prior  conditions  excepted,  and,  shall  furnish  all parts,
         mechanisms,  and devices required to keep the Equipment in good working
         order, prior condition  excepted.  Sublessee hereby assumes all risk of
         loss,  damage,  theft,  or  destruction  of the  Equipment  during  the
         Sublease.

         Sublessor shall either cause Lessor to provide all notifications  under
         the Master Lease  directly to Sublessee  or shall  deliver  immediately
         upon receipt by Sublessor to Sublessee  all  notifications  received by
         Sublessor from Lessor.

13.      BROKER PARTICIPATION

         Sublessor and Sublessee warrant and represent that they have dealt with
         no real  estate  broker in  connection  with the  Sublease  other  than
         Newmark on behalf of the  Sublessor  and Trammel  Crow on behalf of the
         Sublessee  and that no other  broker is entitled to any  commission  on
         account of this  Sublease.  Sublessee  shall have no  obligation to pay
         Newmark any commission or other fees as a result of Sublessee  entering
         into this Sublease.

         Sublessor  shall be  responsible  for payment of any and all  brokerage
         commissions, per a written agreement between Sublessor and Newmark. The
         commission shall be paid upon sublease execution.

15.      FURNITURE, FIXTURES AND EQUIPMENT

         Sublessee shall have use of furniture,  fixtures and Equipment ("FF&E")
         throughout  the term of the Sublease,  subject to normal wear and tear.
         Such FF&E shall be in accordance with Exhibit C. The FF& E shall remain
         property of the Sublessor upon the expiration of the Sublease.

16.      ODIN TECHNOLOGIES

         Sublessee  recognizes that Odin  Technologies  ("OT") will be occupying
         part of the  Premises  through May 31,  2005.  Sublessor  shall have no
         obligation  or liability  to  Sublessee as a result of OT's  occupancy,
         provided,  that  Sublessor has exercised due diligence in enforcing its
         rights  and OT's  obligations  under  the OT  sublease  including  OT's
         obligation to vacate by May 31, 2005.  Sublessor shall credit Sublessee
         any amounts paid by OT to Sublessor  for OT partial use of the premises
         from the date of this  sublease  through May 31,  2005.  Credit will be
         given to Sublessee  against  rent due to Sublessor  for the period July
         15, 2005 - August 15, 2005.

17.      ATTORNEYS' FEES

         If Sublessor or Sublessee  shall  commence an action  against the other
         arising out of or in  connection  with this  Sublease,  the  prevailing
         party shall be  entitled  to recover  its costs of suit and  reasonable
         attorney's fees.

18.      USE OF PREMISES

         Sublessee  shall use the Premises for general  office  purposes and for
         all lawful activities  normally  incidental  thereto and related to the
         conduct of Sublessee's business and for no other purpose.

19.      NOTICES

         All notices and demands which may or are to be required or permitted to

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         be given by either  party on the other  hereunder  shall be in writing.
         All  notices and  demands  shall be sent in person or by United  States
         Certified  or  Registered  Mail,  postage  prepaid,  and to the address
         herein  below,  or to such other  place as the parties may from time to
         time designate in a notice to the other.

         To Sublessor:              Thomas Group, Inc.
                                    Attn:  David English
                                    Williams Square - Las Colinas
                                    5221 North O'Connor Blvd.
                                    Suite 500
                                    Irving, TX 75039


         To Sublessee:              IPIX Corporation
                                    Attn:  Joe Cruz
                                    12120 Sunset Hills Road
                                    Suite 410
                                    Reston, VA  20190

20.      CONDITION OF PREMISES

         Unless  stated in a written  punchlist  delivered to Sublessor by April
         15, 2005 or the date Sublessee  first occupies the premises,  whichever
         is earlier,  Sublessee's taking possession shall be conclusive evidence
         as  against  Sublessee  that  the  Premises  were  in  good  order  and
         satisfactory condition when the Sublessee took possession.

21.      MAINTENANCE OF PREMISES

         Sublessee  shall be  responsible  for  maintenance  of the Premises and
         improvements  in accordance with the terms and conditions of the Master
         Lease regarding same.

22.      INSURANCE

         Sublessee  shall  maintain at its sole cost  throughout the Term hereof
         such  insurance  policies as are required to be maintained by Sublessor
         under the Master Lease,  naming as the insured,  Lessor,  Sublessor and
         Sublessee,  as their  respective  interests may appear,  and contain an
         endorsement that such policy shall not be cancelable except upon thirty
         (30) days prior written notice to Lessor and Sublessor.

23.      INDEMNIFICATION

         Sublessee  assumes  liability  for  and  hereby  agrees  to  indemnify,
         protect,  save and keep  harmless  Sublessor,  its  agents,  employees,
         officers,  directors,  successors and assigns, from and against any and
         all  liabilities,  obligations,  losses,  damages,  penalties,  claims,
         actions,  suits, costs and expenses including reasonable legal expenses
         incurred  by or asserted  against  Sublessor,  its  agents,  employees,
         officers,  directors,  successors and assigns in any way relating to or
         arising out of Sublessee's performance under this Sublease.

         Sublessor  assumes  liability  for  and  hereby  agrees  to  indemnify,
         protect,  save and keep  harmless  Sublessee,  its  agents,  employees,
         officers,  directors,  successors  and assigns from and against any and
         all  liabilities,  obligations,  losses,  damages,  penalties,  claims,
         actions,  suits, costs and expenses including reasonable legal expenses
         incurred  by or asserted  against  Sublessee,  its  agents,  employees,
         officers,  directors,  successors and assigns in any way relating to or
         arising out of Sublessor's performance under this Sublease.

24.      CONSENT BY LESSOR

         As required under the terms of the Master Lease, this Sublease shall be

<PAGE>

         of no force or effect unless  consented to by Lessor within thirty (30)
         days after Sublease execution. Such consent is attached as Exhibit D.

25.      EXHIBITS A, B, C & D ARE HEREBY MADE A PART OF THIS SUBLEASE.

26.      SIGNS

         Sublessee  shall have the right to affix  Sublessee's  name and logo to
         any  available  marquees,  signs,  placards  or on any other  customary
         locations on or within the building where the premises leased hereunder
         is located.

Sublessor:        Thomas Group, Inc.

Date:                 4/22/05
                  -------------------------------------

By:                 /s/ David English
                  -------------------------------------

Title:              Controller
                  -------------------------------------



Sublessee:        IPIX CORPORATON

Date:               4/13/05
                  -------------------------------------

By:                 /s/ Charles A. Crew
                  -------------------------------------

Title:              Executive Vice President
                    and Chief Financial Officer
                  -------------------------------------