Form of Ordinary Share Certificate of Registrant




	
	  
 Exhibit 4.1

 


 



 
 ORDINARY SHARES 
INCORPORATED UNDER THE LAWS OF
IRELAND 
THIS CERTIFICATE IS TRANSFERABLE IN CITIES DESIGNATED BY THE TRANSFER AGENT, AVAILABLE ONLINE AT WWW.COMPUTERSHARE.COM 
This Certifies that 
is the registered holder of 
FULLY PAID AND NONASSESSABLE ORDINARY SHARES OF 
DIRECTOR 
EMBOSSED SEAL 
COMPANY SECRETARY 
Iterum Therapeutics plc 
Iterum Therapeutics plc, par value US $0.01 each, transferable upon
the register of the Company by the registered holder thereof in person or by duly authorized attorney upon surrender of this certificate accompanied by a proper form of transfer, properly endorsed. This certificate and the shares represented hereby
are issued and shall be held subject to all of the provisions of the Articles of Association of the Company, a copy of which is on file with the Transfer Agent, to all of which the holder by acceptance hereof assents. This Certificate is not valid
unless countersigned by the Transfer Agent and registered by the Registrar. Witness the facsimile seal of the Company and the facsimile signatures of its duly authorized officers.Dated: 
ORDINARY SHARES PAR VALUE US$0.01 SHARES 
SEE REVERSE FOR CERTAIN DEFINITIONS 
SECURITY-COLUMBIAN UNITED STATES BANKNOTE CORPORATION 







 ITERUM THERAPEUTICS plc 

On request, the Company will furnish to the record holder of this certificate without charge, a copy of the Constitution of the Company, which
include the express terms of the shares represented by this certificate and other classes and series of shares which the Company is authorized to issue. Any such request is to be addressed to the Company or to the Transfer Agent named on the face of
this certificate. 
 THE TRANSFER OF THESE SHARES REPRESENTED BY THIS CERTIFICATE REQUIRES THE COMPLETION OF A SPECIALIZED STOCK TRANSFER
FORM AND MAY BE SUBJECT TO IRISH STAMP DUTY. PLEASE CONTACT THE TRANSFER AGENT FOR ADDITIONAL INFORMATION. 
 For US purposes the following
abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full according to applicable laws or regulations: 

 

																					
	 TEN COM
	 	 	—	 	 	 as tenants in common
	 	UNIF GIFT MIN ACT	 	 	—	 	 	                                   
                         	 	
Custodian                 
                                      

	 TEN ENT
	 	 	—	 	 	 as tenants by the entireties
	 		 				 	 (Cust)
	 		 	 (Minor)

	 JT TEN
	 	 	—	 	 	 as joint tenants with right
	 		 				 	 under Uniform Gifts to Minors Act
                                         
                                  

		 				 	 of survivorship and not as
	 		 				 		 		 	(State)
		 				 	 tenants in common
	 	UNIF TRF MIN ACT	 	 	—	 	 	
                   
                                         

	 	Custodian (untilage                                
       )
		 				 		 		 				 	(Cust)	 		 	
		 				 		 		 				 	
                          
                           under Uniform Transfer to Minors Act   
              

		 				 		 		 				 	 (Minor)
	 		 		 	 (State)        


 Additional abbreviations may also be used though not in the above list. 

FOR VALUE
RECEIVED,                                      
          hereby sells, assigns and transfers unto 
  

			
		  	
	PLEASE INSERT SOCIAL SECURITY OR OTHER	  	
	IDENTIFYING NUMBER OF ASSIGNEE	  	
	     
	  	
                    
                                         
                                         
                                         
                 



			
	
	     

	PLEASE PRINT OR TYPE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE
	
	     

	
	     

	
	
                       
                                         
                                         
                                         
                                         
                                   Ordinary Shares,


	
	 nominal value US $0.01 each represented by the within Certificate, and do hereby irrevocably constitute and
appoint
                                         
                   

	
	
                       
                                         
                                         
                                         
                                         
                            , as my/our Attorney to transfer the said Ordinary Shares
on the books of the within named Company with full power of substitution in the premises.

	
	Dated                                   
                     

  

			
	 X
	  	  

	 X
	  	  

	 NOTICE:
	  	 THE SIGNATURE(S) TO THIS ASSIGNMENT MUST CORRESPOND WITH THE NAME(S) AS WRITTEN UPON THE FACE OF THE CERTIFICATE IN EVERY
PARTICULAR, WITHOUT ALTERATION OR ENLARGEMENT OR CHANGE WHATEVER.

		  	
		  	


  

			
	Signature(s) Guaranteed:	 	
		
	 By
	 	
	 THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN
ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15.
	 	

  

			
	ABnote North America	 	PROOF OF: MARCH 29, 2018
	711 ARMSTRONG LANE, COLUMBIA, TN 38401	 	ITHERUM THERAPEUTICS PLC
	(931) 388-3003	 	WO - 18000144
FACE                                     OPERATOR: DKS
	SALES: HOLLY GRONER 931-490-7660	 	REV. 1

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