**EXHIBIT      10.1**

**MARK**
**ETING,      SALES and DISTRIBUTION AGREEMENT**

**WITNESSETH**

**WHEREAS**

**WHEREAS      **

**WHEREAS      **

**NOW      THEREFORE **

| **1.** | **APPOINTMENT                  AND ACCEPTANCE** |
|--------|-------------------------------------------------|

|  | 1.1. | CI                  hereby appoints DOLIAGE as CI’s exclusive partner in the Territory.                  Exclusive partner in this Section 1.1 shall mean (i) that CI grants                  DOLIAGE the exclusive right to promote, market, sell and distribute                  the                  Products in the Territory under CI’s Brand name(s) and Trademark(s) and                  that (ii) that CI shall not appoint any other party than DOLIAGE                  to                  promote, market, sell and distribute the Products in the                  Territory |
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|  | 1.2. | CI                  hereby grants DOLIAGE rights, without the right to sublicense,                  to use CI’s                  patents, listed in Schedule A within the Territory for the sole                  purposes                  of carrying out DOLIAGE's obligations under this AGREEMENT. DOLIAGE                  agrees                  to exercise these rights only as are necessary to meet its obligations                  to                  promote, market, sell or distribute the Products in the Territory                  under                  this Agreement. DOLIAGE agrees not use these rights to promote,                  market,                  sell or distribute competitive product(s) within the Territory.                  CI agrees                  not to grant rights under the patents listed in Schedule A which                  would                  allow a competitor to promote, market, sell or distribute a competing                  medical device for the treatment of primary open angle glaucoma                  or ocular                  hypertension within the Territory. Passive sales by other distributors                  within the Territory and sales on part of the customers of CI shall                  not be                  restricted by this provision |
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**____________**

**Confidential          treatment has been requested with respect to certain portions of this          exhibit. Omitted          portions have been filed separately with the Securities and Exchange          Commission.  This exhibit omits the information subject to the          confidentiality request. Omissions are designated as [ * ].**

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|  | 1.3. | DOLIAGE                  accepts such appointment and agrees to use its commercially reasonable                  efforts to promote, develop and increase sales of the Products                  within the                  Territory. Without limiting the generality of the foregoing, DOLIAGE                  shall: |
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|  | 1.3.1. | develop                  and distribute to the best advantage of the Products such literature                  and                  other advertising material as may be agreed to by CI and will not                  use or                  release any advertising or promotional materials (including, without                  limitation, labels, packages, circulars, and advertisements) without                  the                  prior approval of CI. The consent of CI shall not be unreasonably                  withheld. |
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|  | 1.3.2. | solicit                  prospective purchasers who may specify or utilize the                  Products; |
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|  | 1.3.3. | shall                  not promote or sell any other product or other product lines which                  are a                  medical device indicated in the non-surgical treatment of primary                  open                  angle glaucoma or ocular hypertension. |
|--|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 1.3.4. | take                  no action which might impair the goodwill or reputation of CI or                  any of                  its affiliated companies or of the                  Products; |
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|  | 1.3.5. | refrain                  from making quotations or writing letters under the name of CI                  or any of                  its affiliates. The name of CI or its subsidiaries shall not appear                  on                  stationery used by DOLIAGE, except as a marginal note showing for                  example                  “Distributor for Coronado                  Industries”; |
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|  | 1.3.6. | interface                  with customers and potential customers on behalf of CI for inquiries                  with                  respect to the Products and use of the                  Products; |
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|  | 1.3.7. | not                  make claims with respect to indications for the Products that are                  not                  approved by the appropriate Health Authority or other appropriate                  regulatory body; |
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|  | 1.3.8. | purchase                  sufficient quantities of the Products from CI so as to be able                  to maintain                  an adequate supply for resale of the                  Products; |
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|  | 1.3.9. | comply                  with all applicable European and French laws and regulations with                  regard                  to the promotion, marketing, sale and distribution of the Products,                  including any reporting requirements in regards to complaints or                  incidents; |
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|  | 1.4. | promptly                  report to CI, or its European representative which is                  currently     Donowa                    Consulting Srl    Piazza                    Albania 10    00153                    Rome, Italy all                    complaints, incidents or problems it receives relating to the                    Products; |
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|  | 1.5. | follow                  all CI marketing and promotion                  policies. |
|--|------|-----------------------------------------------------------------------------------|

|  | 1.6. | handle                  and store all Products in accordance with French and European laws                  and the                  labeling and instructions for the                  Products. |
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|  | 1.7. | CI                  agrees to support DOLIAGE in the promotion, marketing, sale, distribution                  and/or application for reimbursement of the Products in the Territory                  and                  the technical training for the employees of DOLIAGE. CI may decide,                  at its                  sole discretion, whether such support is possible for and available                  within                  CI. |
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| **2.** | **SUPPLY                  PRICE** |
|--------|-----------------------------------|

|  | 2.1. | The                  Supply Price of the Products to DOLIAGE shall be as outlined                  below; |
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|  | 2.1.1. | PNT                  controllers at **[ * ]** per controller for the first two                  years of the AGREEMENT. For years three (3) and four (4) the price                  will be                  **[ * ]** per controller. For year five (5) until the                  end of                  the original AGREEMENT the costs will be **[ * ]** per                  controller. |
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|  | 2.1.2. | **[                  * ]** per box of 100 rings. Each ring is individually packaged                  in a                  sterile sachet with current                  labeling. |
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|  | 2.2. | CI                  will arrange for shipment of the Products from CI’s manufacturing facility                  to DOLIAGE’ warehouse in France. The cost of shipping the Products from                  CI’s distribution facility to DOLIAGE’s central receiving facility in                  France will be the responsibility of                  CI. |
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|  | 2.3. | Payment                  under Clause 2.11 and 2.22 shall be Net 45 days upon delivery of                  goods to                  DOLIAGES’ facility. |
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|  | 2.4. | The                  above Supply Prices reflect the current PNT controller and PNT                  ring design                  and manufacturing processes. In the event the United States Food                  and Drug                  Administration (USFDA) or any other competent governmental health                  authority (HA) requires modifications to the PNT controller and/or                  the PNT                  ring in order to allow continuing sale within the Territory which                  would                  lead to an increase in the manufacturing costs to CI of more than                  **[ * ]**, then CI would supply proper documentation                  supporting this increase, and the Parties agree to negotiate a                  new Supply                  Price. If DOLIAGE was to challenge the price increase under this                  clause,                  DOLIAGE could have an auditor give an independent confirmation.                  If the                  auditor found the increase was greater than or equal to **[ *                  ]** then DOLIAGE would accept the increase and pay for the                  audit.                  If the increase was less than **[ * ]** then the price would                  remain where it was and CI would pay for the audit. |
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|  | 2.5. | All                  Supply Prices quoted shall be understood as excluding VAT at the                  statutory                  tax rate or custom duties, to the extent payable. All taxes and                  duties due                  on the Products are the responsibility of DOLIAGE. |
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|  | 2.6. | DOLIAGE                  will not sell materials which are provided to them free of                  charge. |
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|  | 2.7. | DOLIAGE                  may return goods, including vacuum units which may require service,                  to CI                  only in accordance with CI’s returned goods policy. Used PNT rings cannot                  be returned to CI. In general CI’s returned goods policy allows for the                  return of goods which are received damaged (Section 16 below) from                  CI.                  Such damaged goods may be returned to CI at CI’s expense. CI will provide                  shipping instructions for such returns. All other returned goods                  will be                  at the cost of DOLIAGE and such costs may be charged against the                  PPL                  (Section 5.2.2.2). |
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|  | 2.8. | CI                  will warrant the controller for a period of **[ * ]**.                  DOLIAGE will coordinate return of equipment under warranty, as                  per the                  instructions of CI, for repair or replacement. The costs of shipping                  the                  equipment under warranty from DOLIAGE’s facility to CI’s facility will be                  the responsibility of CI. |
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|  | 2.9. | CI                  will attempt to repair equipment, which is out of warranty, at                  the request                  of DOLIAGE. DOLIAGE will be responsible for return shipping of                  the out of                  warranty equipment to CI. CI will provide a cost estimate for the                  repair                  and will only proceed if agreed to by DOLIAGE. The cost of shipping                  repaired equipment back to DOLIAGE will be born by DOLIAGE and                  all costs                  incurred by DOLIAGE, which are not reimbursed by DOLIAGE’s customers,                  associated with repair of out of warranty equipment can be charged                  against                  the PPL |
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|  | 2.10. | CI                  will be responsible for the production of the Products, including                  sourcing                  of raw materials, CI guarantees that all Products shipped to DOLIAGE                  will                  be free from defects and in compliance with relevant regulatory                  and                  governmental requirements, including compliance with the requirements                  of                  an EU 2a device classification and applicable cGMP Rules and will                  have                  sufficient expiry dating to allow for distribution through normal                  distribution channels. |
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| **3.** | **SALES                  OF PRODUCT OUTSIDE OF                  TERRITORY** |
|--------|-----------------------------------------------------------------------------|

|  | 3.1. | DOLIAGE                  shall not actively sell the PRODUCTS in territories or to customers                  groups                  which (i) CI allocated exclusively to a third party or (ii) CI                  reserves                  for itself or for a company affiliated with CI. |
|--|------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 3.2. | Passive                  sales outside the TERRITORY and sales on part of the customers                  of DOLIAGE                  shall not be restricted by this                  provision. |
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| **4.** | **PROFIT                  and LOSS CALCULATIONS** |
|--------|---------------------------------------------------|

|  | 4.1. | A                  separate PRODUCT Profit and Loss statement (herein referred to                  as the                  “PPL”) will be established and maintained under this AGREEMENT. All                  charges against and income credited to the PPL will be in line                  with the                  following guidelines. In the event that a specific charge or income                  item                  is not addressed below the PARTIES will discuss, in good faith,                  how to                  incorporate the specific item so that it is consistent and in the                  spirit                  of the guidelines outlined below. |
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|  | 4.1.1. | **[                  * ]** in support of the PRODUCTS within the TERRITORY will                  be born                  by DOLIAGE and included in the PPL. |
|--|--------|---------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 4.1.2. | **[                  * ]** will be credited towards the                  PPL. |
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|  | 4.1.3. | DOLIAGE                  will use best efforts to maximize the profits from sales of the                  PRODUCTS                  which is credited to the PPL |
|--|--------|------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 4.1.4. | DOLIAGE                  will not purposely offer discounts on PRODUCTS within the TERRITORY                  in                  order to increase sales or achieve acceptance of other products                  which                  DOLIAGE or one of its partners sell without the written approval                  of CI. In                  such situations the PARTIES will agree to what additional compensation                  will be credited to CI or the PPL in consideration of the discounts                  that                  were offered on the PRODUCTS within the                  TERRITORY. |
|--|--------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 4.1.5. | CI                  will share the cost of a clinical trial **[ * ]**, up to a                  maximum contribution of **[ * ]** per year during the                  first two years of the contract for a total contribution not to                  exceed                  **[ * ]**. Payment will be made at the end of each calendar                  year upon receipt of an invoice with sufficient detail to explain                  the                  actual costs incurred in performing the trial. Any payments made                  by CI to                  DOLIAGE in support of the clinical trial will be accounted for                  in the                  P&L and accounted for in the calculation of any profit sharing (for                  example as income or an expense offset in the collaboration) so                  as to                  avoid an inappropriate charge against the calculation of the profit                  sharing. The actual schedule of the clinical trial being beyond                  DOLIAGE’s                  control, any delay encountered while undertaking the trial will                  be                  reported by DOLIAGE to CI in order to extend accordingly the two                  years                  time frame originally planned for CI participation to the cost. |
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|  | 4.2. | The                  PARTIES shall agree on the marketing plan and develop a mutually                  agreed                  upon budget for marketing activities related to the PRODUCTS |
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|  | 4.2.1. | DOLIAGE                  will be responsible for all marketing costs for the PRODUCTS within                  the                  TERRITORY. |
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|  | 4.2.2. | All                  external costs **[ * ]** can be charged against the PPL at                  full costs |
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|  | 4.2.3. | **[                  * ]** |
|--|--------|----------------------------|

|  | 4.3. | DOLIAGE                  will build and maintain a sales organization commensurate with                  the sales                  potential of the Products in the Territory and employ sales personnel                  trained with sufficient product knowledge to sell the Products                  adequately                  within the Territory; |
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|  | 4.3.1. | **[                  * ]** |
|--|--------|----------------------------|

|  | 4.3.2. | **[                  * ]** |
|--|--------|----------------------------|

|  | 4.4. | **[                  * ]** |
|--|------|----------------------------|

|  | 4.5. | **[                  * ]** |
|--|------|----------------------------|

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| **5.** | **PROFIT                  SHARING** |
|--------|-------------------------------------|

|  | 5.1. | Revenue                  sharing shall be based on a profit sharing model as outlined                  below. |
|--|------|---------------------------------------------------------------------------------------------------------------|

|  | 5.2. | Profit/loss                  from the sales of PRODUCTS will be calculated as                  follows; |
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|  | 5.2.1. | **[                  * ]** |
|--|--------|----------------------------|

|  | 5.2.1.1. | **[                  * ]**  |
|--|----------|----------------------------------|

|  | 5.2.1.2. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2. | **[                  * ]** |
|--|--------|----------------------------|

|  | 5.2.2.1. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.2. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.3. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.4. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.5. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.6. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.7. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.2.8. | **[                  * ]** |
|--|----------|----------------------------|

|  | 5.2.3. | **[                  * ]**  |
|--|--------|----------------------------------|

|  | 5.3. | **[                  * ]** |
|--|------|----------------------------|

|  | 5.4. | **[                  * ]** |
|--|------|----------------------------|

|  | 5.5. | **[                  * ]** |
|--|------|----------------------------|

|  | 5.6. | The                  budget year for the PPL will coincide with DOLIAGE’s budget year, which                  currently runs from October 1st                  to                  September 30th. |
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|  | 5.7. | DOLIAGE                  will submit the final detailed PPL for the prior budget year, from                  which                  the profit/loss will be calculated, by October 31st                  of                  the current budget year. For example, the final detailed PPL for                  the                  budget year October 1, 2006 to September 30, 2007 will be submitted                  to CI                  by October 31, 2007. CI will have the right to review the detailed                  PPL and                  if they disagree with specific aspects of PPL can request that                  they be                  adjusted. For the budget period from contract initiation until                  September                  30, 2006 the PPL will be prepared and agreed to by May 30,                  2006. |
|--|------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 5.8. | In                  the event that the PARTIES cannot agreed on whether a specific                  charge or                  income item should be included on the PPL, the PARTIES will have                  an                  independent auditor, acceptable to both PARTIES with such acceptance                  not                  to be unreasonably withheld, review the PPL and render a decision                  on                  whether the charge is valid. The PARTIES will share the costs of                  the                  audit |
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|  | 5.9. | CI                  can request once a year that an independent auditor, acceptable                  to both                  PARTIES with such acceptance not to be unreasonably withheld, review                  the                  entire PPL and all supporting documentation to verify that the                  PPL was                  prepared in compliance with this AGREEMENT. If it is found that                  additional                  monies are owed CI as a result of the audit then DOLIAGE will pay                  the                  additional funds. If the amount of the additional monies owed CI                  is                  greater than 10% of the monies originally calculated in the PPL                  the costs                  of the external auditor will be borne by DOLIAGE otherwise the                  costs of                  the external auditor will be the responsibility of CI. DOLIAGE                  will                  provide its own resources for such audit at no cost. Reasonable                  advance                  notice should be given by CI of its intention to perform such an                  audit,                  and reasonable usage of DOLIAGE resources will be made, so as not                  to                  affect DOLIAGE’s operation. |
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|  | 5.10. | The                  PARTIES will use best efforts to finalize and close the PPL for                  the prior                  budget year by December 1st                  of                  the current budget year. For example, the PPL for the period October                  1st,                  2006, to September 30th, 2007 should be finalized and closed by                  December                  1st,                  2007. |
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|  | 5.11. | **[                  * ]** |
|--|-------|----------------------------|

| **6.** | **BUDGETS** |
|--------|-------------|

|  | 6.1. | DOLIAGE                  will prepare a budget in line with the Sales and Marketing plan                  agreed to                  by the PARTIES. The PARTIES must mutually agree and approve each                  annual                  budget by December 31st                  of                  the prior year. For example the annual budget for the period October                  1st                  2006 to September 30th                  2007 should be approved by December 31st,                  2006. |
|--|------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 6.2. | If                  the PARTIES do not agree on the budget submitted by DOLIAGE the                  PARTIES                  will discuss in good faith such differences and utilize best efforts                  to                  reach agreement on the annual                  budget. |
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| **7.** | **FORECASTING** |
|--------|-----------------|

|  | 7.1. | On                  the first day of each calendar quarter, DOLIAGE shall provide CI                  with a                  written rolling forecast of the requirement for the Products, per                  month,                  for the then current calendar quarter and the next 3 (three) calendar                  quarters. The forecast for the then current calendar quarter shall                  be                  binding, for the remaining calendar quarter’s non-binding. |
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|  | 7.2. | At                  least three (3) months in advance of the requested delivery date                  of the                  Products, DOLIAGE shall submit to CI a written purchase order for                  the                  desired quantities of the Products (hereinafter referred to as“Purchase                  Order”). All Purchase Order shall be firm and binding upon the Parties                  and                  shall bear the exact quantity ordered and the agreed upon delivery                  date. |
|--|------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| **8.** | **RELATIONSHIP                  OF THE PARTIES** |
|--------|--------------------------------------------------|

| **9.** | **NOTICES** |
|--------|-------------|

| If to DOLIAGE:  | Laboratories DOLIAGE                          |
|-----------------|----------------------------------------------------|
|            | 81 rue de Verdun,                             |
|            | 92150 Suresnes,                               |
|            | France                                        |
|            | Facsimile: (33) 1 41 38 29                55  |
|            | Attention: CEO                                |
|            |                                               |
| If to CI:  | Coronado Industries                           |
|            | 16857 Saguaro Blvd                            |
|            | Fountain Hills, Arizona                85268  |
|            | USA                                                |
|            | Attention: CEO                                     |
|            | CC: Director                of Operations     |
|            | Facsimile +1 480 837                6870           |

| **10.** | **FORCE                  MAJEURE** |
|---------|------------------------------------|

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| **11.** | **TRADEMARKS                  AND PATENTS** |
|---------|---------------------------------------------|

|  | 11.1. | CI                  will be responsible for registering and maintaining all applicable                  Patents                  within the Territory as listed in Schedule B (hereinafter referred                  to as                  “Patents”) relating to the Products in the Territory at CI’s                  costs. |
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|  | 11.2. | By                  virtue of the Agreement and DOLIAGE’s performance hereunder, DOLIAGE shall                  acquire no interest in CI trademarks or corporate names, label                  designs or                  other identifying marks used to distinguish CI’s Products. Except for                  undertaking such activities as are directly related to promoting                  the sale                  of the Product under this Agreement, DOLIAGE shall not make use                  of the                  name CI, or make use of any trademark or trade name which in the                  judgment                  of CI is confusingly similar thereto without the written consent                  of                  CI. |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 11.3. | The                  Parties will use their best efforts to discover any infringement                  of any                  Patent, Trademark or corporate name of Coronado Industries and                  will                  promptly notify each other of any such infringement or wrongful                  use. Any                  Proprietary Information provided shall be and remain the property                  of CI,                  and CI will impose any conditions with respect thereto which it                  deems                  reasonably necessary to preserve the confidential nature thereof.                  DOLIAGE                  will retain all Proprietary Information in strict confidence as                  trade                  secrets of CI and will not disclose, or permit any employee or                  agent of                  DOLIAGE to disclose, any Proprietary Information to anyone without                  the                  prior written approval of CI, provided, however, that such disclosure                  may                  be made to any employee of DOLIAGE who has a reasonable need for                  access                  thereto. For the purpose of this Agreement, the term “Proprietary                  Information” shall mean all formulae, processes, and other information                  relating to the distribution, sale, and use of any Product which                  has been                  or may hereafter be furnished to DOLIAGE and which would not be                  available                  to the general public otherwise than through violation of this                  Agreement. |
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|  | 11.4. | CI                  shall use its best efforts so that DOLIAGE will not incur any claim                  of                  patent infringement as a result of distribution of the Products                  within the                  Territory under this Agreement. If such claims arise, and are attributable                  to the actions of DOLIAGE allowed under this Agreement, CI will                  at its own                  costs use reasonable efforts to interfere and resolve the issue.                  DOLIAGE                  will notify CI immediately of any claims of patent infringement.                  Any                  liability for damages from an infringement as a direct result of                  the sale                  of the Products by DOLIAGE under the terms of this Agreement, will                  be the                  responsibility of CI. DOLIAGE will cooperate fully with CI to resolve                  and/or defend against any claim of infringement under this                  Agreement. |
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|  | 11.5. | If                  DOLIAGE is aware of a patent infringement on its territory, DOLIAGE                  will                  inform CI, and CI will at its own cost take any action to protect                  the                  patent rights. |
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|  | 11.6. | Upon                  the expiration or prior termination of this Agreement, DOLIAGE                  will                  exercise all necessary precautions to safeguard the secrecy of                  Proprietary                  Information and to prevent the unauthorized disclosure thereof,                  DOLIAGE                  will consult CI as to the procedures established by it for this                  purpose                  and will from time to time, if requested by CI, advise CI of the                  procedures which it then has in effect. |
|--|-------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| **12.** | **REGISTRATIONS                  AND HEALTH AUTHORITY                  INTERACTIONS** |
|---------|---------------------------------------------------------------------------------------|

|  | 12.1. | CI,                  with the assistance of DOLIAGE, will be responsible for all interactions                  with the relevant Health Authorities (HA’s), including but not limited to                  the Type 2a device classification filling of the Product and any                  maintenance of the Type 2a filling with the relevant                  authorities. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 12.2. | DOLIAGE                  will bear the costs associated with any additional registration(s)                  with or                  applications to the relevant Health Authority(s) within in the                  Territory                  which are required to sell the                  Products. |
|--|-------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 12.3. | DOLIAGE,                  as reasonably requested by CI, will assist, provide expertise and                  interact                  as required in dealing with the relevant HA’s in the                  Territory. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 12.4. | CI                  and DOLIAGE agree that a Type 2a device classification is required                  to                  allow the sale of the Products in the Territory. CI agrees to supply                  DOLIAGE with Products meeting this classification and will not                  knowingly                  or negligently ship Products which does not meet this                  classification. |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| **13.** | **CLINICAL                  TRIAL** |
|---------|-------------------------------------|

|  | 13.1. | DOLIAGE                  will be allowed to perform, in collaboration with CI, clinical                  trials in                  order to enhance the marketability of the PRODUCTS within the                  TERRITORY |
|--|-------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 13.2. | The                  clinical trials will involve up to 2/4 centers and approximately                  100                  patients. |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------|

|  | 13.3. | The                  protocols for the clinical trials will be approved by both Parties                  and                  respective Ethical Committees prior to initiation of the                  study. |
|--|-------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 13.4. | The                  costs of performing the clinical trial will be born by DOLIAGE.                  CI will                  reimburse DOLIAGE as outlined Section 4.1.5                  above |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 13.5. | DOLIAGE                  will have in place confidentiality agreements with all clinicians                  involved                  with the clinical trial. DOLIAGE will do its best to prevent any                  non-agreed dissemination regarding the clinical trial or its results                  without the prior consent of CI. |
|--|-------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 13.6. | All                  information developed as part of the clinical trial will be considered                  as                  Confidential Information (as defined below under Section 14) and                  cannot be                  used for any other purpose by DOLIAGE other than to promote the                  Products                  in a way which is beneficial for the Product. In the event the                  AGREEMENT                  is terminated then all information collected under this Agreement,                  including the information gathered as part of the clinical trial                  will                  become the property of CI. DOLIAGE also acknowledges that it will                  not use                  any of the information obtained under this Agreement, including                  information obtained as part of the clinical trial, to promote                  another                  device which would compete with the                  PRODUCTS. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| **14.** | **TERM                  AND TERMINATON** |
|---------|------------------------------------------|

|  | 14.1. | The                  term of this Agreement shall be for a period of eight (8) years                  from the                  Effective Date of this Agreement (hereinafter referred to as “Initial                  Term”). Following the Initial Term outlined above, this Agreement willbe                  automatically renewable on an annual basis, unless either Party                  notifies                  the other 6 months prior to expiration of the Initial Term, or                  each annual                  extension, of their intention not to                  renew. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 14.2. | If                  DOLIAGE’s cumulative losses, which will be calculated as their costs                  directly associated with the AGREEMENT less any monies from the                  envisioned                  profit share, over the first two years of the AGREEMENT exceed                  150,000                  Euros DOLIAGE will have an option to request a renegotiation of                  the                  AGREEMENT and if CORONADO declines to terminate the                  AGREEMENT |
|--|-------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.3. | CI                  shall have the option to terminate, upon ninety (90) days’ written notice,                  if ownership or control (for example. greater than 50.01 % of the                  shares)                  of DOLIAGE is transferred to a third party, which is considered                  by CI to                  be detrimental for CI’s interests. Either Party may terminate this                  Agreement if the other Party is adjudged bankrupt, files or has                  filed                  against it any petition under any bankruptcy or insolvency law,                  has a                  receiver appointed for its business or property, or makes a general                  assignment for the benefit of its                  creditors. |
|--|-------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.4. | DOLIAGE                  hereby accords CI upon termination or expiration of this Agreement                  an                  option to repurchase from DOLIAGE all or any part of DOLIAGE’ inventory of                  that Products, which DOLIAGE will not need in order to fulfill                  its                  delivery commitments towards its customers for commitments which                  can be                  documented were made prior to termination of expiration of this                  Agreement                  (hereinafter referred to as “Inventory Products”), at the price paid                  therefore by DOLIAGE (hereinafter referred to as “Repurchase Price”),                  pursuant to the following                  procedures: |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.4.1. | Within                  five (5) days after the effective date of termination, DOLIAGE                  shall                  submit to CI a written schedule reflecting all Inventory Products                  then                  owned by or in DOLIAGE’ possession. Said schedule shall identify each                  Inventory Product and shall indicate the quantity thereof on                  hand. |
|--|---------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.4.2. | Within                  ten (10) days after the receipt of such schedule by CI, CI shall                  have the                  right to inspect the inventory reflected on such                  schedule. |
|--|---------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.4.3. | Within                  five (5) days after completion of CI’s inspection of said inventory, CI                  shall give written notice of its election to repurchase all or                  any part of                  the Inventory Products. |
|--|---------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.4.4. | Upon                  receipt of said notice of repurchase, DOLIAGE shall forthwith deliver                  such                  Inventory Products as may be specified therein to a carrier designated                  by                  CI and at the costs of CI. Payment of the Repurchase Price as hereinabove                  provided shall be made by CI to DOLIAGE within five (5) days after                  the                  delivery of said Products to                  carrier. |
|--|---------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.5. | Upon                  termination or expiration of this Agreement, DOLIAGE shall immediately                  cease to represent itself as an authorized distributor of CI with                  respect                  to the Products. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.6. | CI                  can elect, but will have no obligation, to provide additional product                  in                  order to allow DOLIAGE’ to fulfill commitments towards its customers                  following termination or expiration of this                  Agreement. |
|--|-------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.7. | The                  termination or expiration of this Agreement shall not release either                  Party                  from the obligation to pay any sum that may be owing to the other                  Party or                  operate to discharge any liability that had been incurred by either                  Party                  prior to any such termination. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 14.8. | Failure                  by a Party to comply with any of its material obligations contained                  in                  this Agreement, including payment term obligations, shall entitle                  the                  non-defaulting Party to give to the defaulting Party written notice                  specifying the nature of the default and requiring the defaulting                  Party to                  make good such default. If such default is not cured within sixty                  (60)                  days after the receipt of such notice (or, if such default is not                  capable                  of being cured within such sixty (60) day period, within such amount                  of                  time as may be reasonably necessary to cure such breach, as long                  as the                  Defaulting Party is making diligent efforts to do so, except in                  the case                  of payment default, as to which the defaulting Party shall have                  only a                  sixty (60) day cure period), the non-defaulting Party shall be                  entitled                  immediately to terminate this Agreement by giving written notice                  to the                  defaulting Party. The right of a Party to terminate this Agreement,                  as                  hereinafter provided, shall not be affected in any way by its waiver                  or                  failure to take action with respect to any previous                  default. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.9. | The                  Parties may agree in writing, signed by both Parties, to terminate                  this                  Agreement in its entirety. In such an event, the Parties shall                  agree to                  the effects of such termination at that                  time. |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.10. | If                  the PARTIES cannot agree on the annual budget as outlined under                  Clause 6                  by November 15th                  of                  the prior year then either PARTY may elect to terminate this                  AGREEMENT. |
|--|--------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 14.11. | In                  the event this AGREEMENT is terminated under clause 14.10 above                  then                  Clauses 14.4, 14.4.1, 14.4.2, 14.4.3, 14.4.4, 14.4.5, 14.5, 14.6                  and 14.7                  will apply. |
|--|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| **15.** | **CONFIDENTIALITY** |
|---------|---------------------|

| **16.** | **ASSIGNMENT** |
|---------|----------------|

|  | 16.1. | This                  Agreement shall be binding upon the successors and assignees of                  CI and                  DOLIAGE. |
|--|-------|-----------------------------------------------------------------------------------------------------------------------------------------|

|  | 16.2. | Either                  Party may assign this Agreement to a wholly owned subsidiary or                  other                  entity in which the transferring Party has a majority share and                  operational control. In case of such an assignment, the assigning                  party                  will remain jointly and severally liable for all of its obligations                  under                  this Agreement. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 16.3. | This                  Agreement shall not be assignable by either Party to an independent                  third                  party, without the prior written consent of the other Party, such                  consent                  not to be unreasonably withheld. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| **17.** | **INDEMNIFICATION                  / DEFECTS OF THE PRODUCTS** |
|---------|----------------------------------------------------------------|

|  | 17.1. | CI                  will indemnify, defend and hold harmless DOLIAGE from any and all                  liability, loss, or damage DOLIAGE may suffer as a result of claims,                  demands, costs, or judgment against it arising from product liabilities                  of                  any kind under any jurisdiction provided that such product liability                  is                  not based on DOLIAGE’ negligence in storing, maintaining, labeling,                  promoting or selling the Products or otherwise failing to comply                  with                  applicable laws and regulations and the terms of this Agreement.                  In the                  latter case, DOLIAGE will indemnify, defend and hold harmless CI                  from any                  and all liability, loss or damage CI may suffer as a result of                  such                  claims, demands, costs or judgments against it. |
|--|-------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 17.2. | For                  the duration of this Agreement, each Party will maintain, at each                  Party’s                  own expense, insurance coverage from a reputable insurance carrier                  in the                  amount of a minimum of USD $1.0 million per incidence. Upon request                  of a                  Party, the other Party shall submit a copy of the respective certificate                  of insurance. |
|--|-------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 17.3. | DOLIAGE                  shall inspect the delivered Products immediately following delivery                  by CI                  insofar it is practicable in the orderly course of business and                  notify                  apparent defects to CI within 14 days after their discovery. All                  other                  defects, such as hidden defects, will be notified by DOLIAGE within                  14                  days after their discovery. |
|--|-------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 17.4. | If                  (i) the Products delivered by CI are agreed by the Parties to be                  defective                  and/or (ii) if it turns out and the Parties agree that the Products                  were                  damaged prior to receipt by DOLIAGE and/or (iii) the Parties agree                  that                  the Products do not have the agreed upon quality, DOLIAGE shall                  have the                  right to request defect-free goods as replacement. In the event                  that CI                  cannot deliver within 45 days following notification by DOLIAGE                  and                  agreement between the Parties that the Products are defective as                  described                  under (i) - (iii) above DOLIAGE will have the right to cancel the                  respective individual orders involving the above goods and receive                  a                  refund of any monies paid to CI. Removal and return deliveries                  of                  defective Products shall be effected at CI ́s costs and                  risk. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| **18.** | **MISCELLANEOUS** |
|---------|-------------------|

|  | 18.1. | The                  provisions of this Agreement shall be construed and the performance                  thereof governed in accordance with the laws of the State of New                  York,                  USA. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.2. | All                  sub-distributors selected by DOLIAGE must be pre-approved by CI.                  The                  consent of CI shall not be unreasonably withheld. In the event                  that                  DOLIAGE becomes aware that a sub-distributor is in violation of                  any part                  of this Agreement DOLIAGE will immediately inform CI and will take                  all                  necessary actions to ensure compliance with this Agreement by the                  sub-distributor. |
|--|-------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.3. | The                  article headings in this Agreement are inserted for convenience                  only and                  shall not be deemed to be part of this Agreement or considered                  in                  construing this Agreement. |
|--|-------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.4. | This                  Agreement constitutes the entire understanding between the Parties                  and                  supersedes any previous written or oral agreements or understandings                  between the Parties. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.5. | No                  modification to or waiver of the terms or conditions hereof shall                  be                  binding upon either Party unless approved in writing by an authorized                  representative and no modification can be made by the acknowledgment                  of                  acceptance or by the use of purchase order forms containing other                  or                  different terms or conditions. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.6. | This                  Agreement may be executed in one or more counterparts, each of                  which shall                  be deemed an original but all of which shall constitute one and                  the same                  instrument. |
|--|-------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 18.7. | Should                  the effects of this Agreement resulting from future unforeseen                  events and                  developments lead to an unjust hardship for either Party and which                  hardship does not correspond with the intention of the Parties                  in good                  faith, the Parties shall without delay enter into negotiations                  to see in                  what way the conditions of the Agreement can be modified to suit                  altered                  circumstances. |
|--|-------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.8. | Neither                  the general terms of sale and delivery of CI nor the general terms                  of                  purchase of DOLIAGE shall apply to this Agreement or the individual                  transactions concluded on its basis. This shall also apply if either                  Party                  refers to its general terms and conditions when concluding an individual                  transaction. |
|--|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 18.9. | All                  disputes arising out of or in connection with this Agreement shall                  first                  be attempted to be settled between the Parties on a good faith                  basis. If                  the Parties are unable to resolve the dispute within 60 (sixty)                  days from                  the receipt by one Party of the other Party’s written notice asking for                  such amicable settlement discussions, then such dispute shall be                  finally                  settled by arbitration in accordance with the International Chamber                  of                  Commerce (ICC) Rules of Arbitration by three arbitrators, appointed                  in                  accordance with said rules. The place of arbitration shall be New                  York                  City, New York, USA. The proceedings shall be conducted and all                  documentation shall be presented in                  English. |
|--|-------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| **19.** | **SCHEDULES** |
|---------|---------------|

|  | 19.1. | Schedule                  A:   Products |
|--|-------|--------------------------------------------------------|

|  | 19.2. | Schedule                  B:    Patent |
|--|-------|------------------------------------------------------------|

**IN        WITNESS THEREOF**

| **CORONADO                INDUSTRIES, Inc.**  |      | **Laboratories                DOLIAGE** |
|----------------------------------------------------|-----------|-----------------------------------------|
|                                               |      |                                    |
| By:                                      | /s/  |                                    | By:   | /s/  |
|                                               |           |                                    |   |  |
|                                               | NameTitle |                                    |   | NameTitle |

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**SCHEDULE        A**

| Products  |   |                                                                                                                                                                                                                             |
|----------------|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|           |   | PNT Vacuum Controller - Model                1000                                                                                                                                                                                |
|           |   |                                                                                                                                                                                                                             |
|           |   | PNT Sterilized/Single Use/Disposable                Ring -                pre-sterilized polypropylene 3-port PNT ring. One (1) sterilized                ring per                sealed Tyvek® pouch. 100 rings per carton |

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**SCHEDULE        B**

| Patents  |   |                                                                                                                                   |
|---------------|--------|----------------------------------------------------------------------------------------------------------------------------------------|
|          |   | Patent Number 0790803 ‘Open Angle Glaucoma                  Treatment Apparatus’ issued February 19,                  2003 |

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