SECURITIES AND EXCHANGE COMMISSION
                                 WASHINGTON, DC

                                    FORM 10-Q

(Mark One)

 X   Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange
---  Act of 1934

                  For the quarterly period ended March 31, 1999
                                                 --------------

                                       or

_____Transition Report Pursuant to Section 13 or 15(d) of the Securities
Exchange Act of 1934

               For the transition period from _____________ to ________________

                              Commission File Number:   0-28748
                                                        -------

                           CLOSURE MEDICAL CORPORATION
                           ---------------------------
             (Exact name of registrant as specified in its charter)


            Delaware                              56-1959623
            --------                              ----------
         (State or other                       (I.R.S. Employer
          jurisdiction                       Identification No.)
      of incorporation or
         organization)

              5250 Greens Dairy Road, Raleigh, North Carolina 27616
              -----------------------------------------------------
                  (Address of principal executive offices) (Zip
                                      Code)

                                 (919) 876-7800
                                 --------------
              (Registrant's telephone number, including area code)
        ----------------------------------------------------------------

        Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.

        Yes X                                              No 
           ---                                               ---

        Indicate the number of shares outstanding of each of the issuer's
classes of common stock, as of the latest practicable date.


            Class                               Outstanding at May 11, 1999
            -----                               ------------------------
Common Stock, par value $0.01 per share                13,309,809




<PAGE>


                           CLOSURE MEDICAL CORPORATION

                                      INDEX
<TABLE>
<CAPTION>
                                                                                   Page Number
                                                                                   -----------
PART I:      FINANCIAL INFORMATION

        Item 1.  Financial Statements

<S>                                    <C> <C>                           <C> <C>            <C>
            Balance Sheets as of March 31, 1999 (unaudited) and December 31, 1998............3


            Statements of Operations (unaudited) for the three months ended March 31,
               1999 and 1998.................................................................4

            Statements of Cash Flows (unaudited) for the three months ended March 31,
               1999 and 1998.................................................................5

            Notes to Condensed Financial Statements (unaudited)..............................6

        Item 2.Management's Discussion and Analysis of Financial Condition and
               Results of Operations.........................................................8

        Item 3.Quantitative and Qualitative Disclosure about Market Risk....................11

PART II:     OTHER INFORMATION

        Item 6.Exhibits and Reports on Form 8-K.............................................12
</TABLE>


                                       2
<PAGE>



                          PART I- FINANCIAL INFORMATION

ITEM 1.   FINANCIAL STATEMENTS

                           CLOSURE MEDICAL CORPORATION
                                 BALANCE SHEETS
                        (In thousands, except share data)

<TABLE>
<CAPTION>
                                                                             MARCH 31,        DECEMBER 31,    
                                                                               1999               1998        
                                                                               ----               ----        
Assets                                                                      (Unaudited)                       
<S>                                                                      <C>              <C>                 
Cash and cash equivalents                                                $           508  $              824  
Short-term investments                                                            11,750              14,275  
Restricted investments                                                             1,500               1,603  
Accounts receivable                                                                1,799               1,191  
Inventories                                                                        1,053               1,008  
Prepaid expenses                                                                     257                 286  
                                                                         ---------------  ------------------  
   Total current assets                                                           16,867              19,187  
Furniture, fixtures and equipment, net                                             8,331               7,707  
Intangible assets, net                                                               570                 526  
                                                                         ---------------  ------------------  
   Total assets                                                          $        25,768  $           27,420  
                                                                         ===============  ==================  
Liabilities and Stockholders' Equity                                                                          
Accounts payable                                                         $         1,195  $            1,721  
Accrued expenses                                                                   1,214               1,705  
Deferred revenue                                                                   1,079               1,245  
Capital lease obligations                                                            185                 245  
Current portion of long-term debt                                                  2,500               2,650  
                                                                         ---------------  ------------------  
   Total current liabilities                                                       6,173               7,566  
Deferred revenue                                                                     670                 670  
Capital lease obligations                                                            934                 934  
                                                                         ---------------  ------------------  
   Total liabilities                                                               7,777               9,170  
                                                                         ---------------  ------------------  
                                                                                                              
Commitments and Contingencies (See note 6)                                             -                   -  
                                                                                                              
Preferred Stock, $.01 par value.  Authorized 2,000 shares; none          
   issued or outstanding.                                                              -                   -  
Common Stock, $.01 par value.  Authorized 35,000 shares;                                      
   issued and outstanding 13,308 and 13,290 shares, respectively.                    133                 133  
Additional paid-in capital                                                        46,588              46,358 
Accumulated deficit                                                              (28,413)            (27,848)
Deferred compensation on stock options                                              (317)               (393)
                                                                         ---------------  ------------------ 
   Total stockholders' equity                                                     17,991              18,250 
                                                                         ---------------  ------------------ 
   Total liabilities and stockholders' equity                            $        25,768  $           27,420 
                                                                         ===============  ================== 
</TABLE>                                                                 
The accompanying notes are an integral part of these financial statements.

                                       3
<PAGE>




                           CLOSURE MEDICAL CORPORATION
                            STATEMENTS OF OPERATIONS
                                   (Unaudited)
                      (In thousands, except per share data)

<TABLE>
<CAPTION>
                                                                    THREE MONTHS ENDED
                                                               MARCH 31,          MARCH 31,
                                                                 1999               1998
                                                                 ----               ----
<S>                                                        <C>                <C>
Product sales                                              $         3,817    $          770
Cost of products sold                                                1,176               534
                                                             --------------     -------------
      Gross profit                                                   2,641               236
                                                             --------------     -------------
Research, development and regulatory affairs expenses                1,862             1,358
General and administrative expenses                                  1,489             1,100
                                                             --------------     -------------
      Total operating expenses                                       3,351             2,458
                                                             --------------     -------------
Loss from operations                                                  (710)           (2,222)
Interest expense                                                       (91)              (88)
Investment and interest income                                         236               354
                                                             --------------     -------------
Net loss                                                   $          (565)   $       (1,956)
                                                             ==============     =============

Shares used in computation of net loss per
    share- basic and diluted                                        13,304            13,252
                                                             ==============     =============

Net loss per share- basic and diluted                      $         (0.04)   $        (0.15)
                                                             ==============     =============
</TABLE>

   The accompanying notes are an integral part of these financial statements.

                                       4
<PAGE>


                           CLOSURE MEDICAL CORPORATION
                            STATEMENTS OF CASH FLOWS
                                   (Unaudited)
                                 (In thousands)

<TABLE>
<CAPTION>
                                                                         THREE MONTHS ENDED
                                                                       MARCH 31,        MARCH 31,
                                                                         1999             1998
                                                                         ----             ----
<S>                                                                       <C>              <C>
Cash flows from operating activities:
Net loss                                                               $   (565)      $ (1,956)
Adjustments to reconcile net loss to net cash
provided (used) by operating activities:
Depreciation and amortization expense                                       227             67
Amortization of deferred compensation on stock options                       76             75
Net loss on disposals of fixed assets                                         3              9
Change in accounts receivable                                              (608)           795
Change in inventories                                                       (45)          (191)
Change in prepaid expenses                                                   29              6
Change in accounts payable and accrued expenses                          (1,017)          (247)
Change in deferred revenue                                                 (166)             6
                                                                         -------        ------                          
Net cash used by operating activities                                    (2,066)        (1,436)
                                                                         -------        ------

Cash flows from investing activities:
Purchases of furniture, fixtures and equipment                             (851)        (2,201)
Investment in intangible assets                                             (47)          (102)
Purchases of investments                                                 (1,104)        (2,805)
Proceeds from the sale of investments                                     3,732          2,552
                                                                         -------        ------ 
Net cash provided (used) by investing activities                          1,730         (2,556)
                                                                         -------        ------  
Cash flows from financing activities:
Proceeds from borrowings                                                      -          1,500
Repayment of debt                                                          (150)             -
Net proceeds from sales of common stock                                     230             92
Payments under capital lease obligations                                    (60)           (56)
                                                                         -------        ------
Net cash provided by financing activities                                    20          1,536
                                                                         -------        ------   
Decrease in cash and cash equivalents                                      (316)        (2,456)
Cash and cash equivalents at beginning of period                            824          7,277
                                                                         -------        ------
Cash and cash equivalents at end of period                             $    508       $  4,821
                                                                         =======        ======
                     

The accompanying notes are an integral part of these financial statements.


</TABLE>


                                       5
<PAGE>





                           CLOSURE MEDICAL CORPORATION
                     NOTES TO CONDENSED FINANCIAL STATEMENTS
                                   (UNAUDITED)


1.  Organization and Operations

Closure Medical Corporation ("Closure" or the "Company"), formerly named
Tri-Point Medical Corporation, develops, manufactures and commercializes medical
tissue cohesive products based on its proprietary cyanoacrylate technology for
use in wound closure in humans and animals.

On September 30, 1996, the Company sold 2,550,000 shares of Common Stock in its
initial public offering ("IPO"). On April 2, 1997, the Company completed a
follow-on public offering selling 1,025,000 shares of Common Stock. The net
proceeds from the IPO and follow-on public offering of approximately $17.9
million and $12.0 million, respectively, have been and will continue to be used
primarily for capital expenditures related to laboratories, office space and
manufacturing facilities, research and development, including clinical trials,
working capital and general corporate purposes.

2.  Significant Accounting Policies

The significant accounting policies followed by the Company for interim
financial reporting are consistent with the accounting policies followed for
annual financial reporting. These unaudited financial statements have been
prepared in accordance with Rule 10-01 of Regulation S-X, and in Management's
opinion, all adjustments of a normal recurring nature necessary for a fair
presentation have been included. Accordingly, they do not include all of the
information and footnotes required by generally accepted accounting principles
for complete financial statements and should be read in conjunction with the
financial statements and notes thereto for the year ended December 31, 1998
included in the Company's Annual Report on Form 10-K for the year ended December
31, 1998.

The results of operations for the three month period ended March 31, 1999 are
not necessarily indicative of the results to be expected for the full year
ending December 31, 1999.

Statement of Financial Accounting Standards No. 133, "Accounting for Derivative
Instruments and Hedging Activities" ("SFAS 133"), was issued in June 1998. SFAS
133 is effective for financial statements for fiscal years beginning after June
15, 1999. The Company will adopt SFAS 133 on or before the effective date;
however, it is not anticipated that this standard will have a material impact on
the results of operations or financial position of the Company.

3.  Taxes

No federal or state income tax provision has been provided for income tax
purposes, as the Company does not expect to have a tax liability for the year
ending December 31, 1999. Additionally, the deferred tax asset that might be
recorded as a result of net operating losses under Statement of Financial
Accounting Standards No. 109, "Accounting for Income Taxes," has been offset by
a related valuation allowance because realization of the asset is not likely.
Accordingly, no benefit has been recorded.

4.  Inventories

Inventories included the following (in thousands):

                              March  31,           December 31,
                                 1999                 1998
                             ----------            ----------
Packaging                    $      175            $      86
Raw materials                        76                  106
Work-in-process                     461                  616
Finished goods                      341                  200
                             ----------            ----------
                             $    1,053            $   1,008
                             ----------            ----------


                                       6
<PAGE>

                           CLOSURE MEDICAL CORPORATION
                     NOTES TO CONDENSED FINANCIAL STATEMENTS
                                   (UNAUDITED)




5.      Net Loss Per Share

Basic net loss per share is computed using the weighted average number of common
and common equivalent shares outstanding during the periods.

Diluted net loss per share is computed using the weighted average number of
common and common equivalent shares outstanding during the periods. Common
equivalent shares consist of stock options using the treasury stock method.
Common equivalent shares from stock options are excluded from the computation if
their effect is antidilutive.

6.      Commitments and Contingencies

In December 1998, a former employee of the Company filed a discrimination claim
with the Raleigh Area Office of the Equal Employment Opportunity Commission. The
Company has retained counsel in this matter and management believes that the
outcome will not have a material adverse effect on the Company.


                                       7
<PAGE>


 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
                             RESULTS OF OPERATIONS


The following discussion should be read in conjunction with the unaudited
financial statements and notes thereto included in Part I--Item 1 of this Form
10-Q and the audited financial statements and notes thereto and Management's
Discussion and Analysis of Financial Condition and Results of Operations for the
year ended December 31, 1998 contained in the Company's Annual Report on Form
10-K for the year ended December 31, 1998.

The statements set forth below that are not historical facts or statements of
current conditions are forward-looking statements. Such forward-looking
statements may be identified by, among other things, the use of forward-looking
terminology such as "believes," "expects," "forecasts," "estimates," "plans,"
"continues," "may," "will," "should," "anticipates," or "intends" or the
negative thereof or other variations thereon or comparable terminology, or by
discussions of strategy or intentions. These forward-looking statements, such as
statements regarding present or anticipated scientific progress, development of
potential products, future revenues, capital expenditures and research and
development expenditures, future financings and collaborations, management,
manufacturing development and capabilities, regulatory clearances and approvals
and other statements regarding matters that are not historical facts, involve
predictions. The Company's actual results, performance or achievements could
differ materially from the results expressed in, or implied by, these
forward-looking statements. Potential risks and uncertainties that could affect
the Company's actual results, performance or achievements include, but are not
limited to, the "Risk Factors" set forth in the Company's Annual Report on Form
10-K for the year ended December 31, 1998 filed with the Securities and Exchange
Commission. Given these uncertainties, current or prospective investors are
cautioned not to place undue reliance on any such forward-looking statements.
Furthermore, the Company disclaims any obligation or intent to update any such
factors or forward-looking statements to reflect future events or developments.

OVERVIEW

Since its inception in May 1990, the Company has been developing, manufacturing
and commercializing medical tissue cohesive products for use in wound closure in
humans and animals. The Company's products are based on its proprietary
cyanoacrylate technology, and a substantial portion of the Company's historical
expenses have consisted of research and development and clinical trial expenses.
Through September 25, 1996, the effective date of the Company's initial public
offering, the Company had funded its operations with cash borrowed from
Sharpoint Development Corporation ("Sharpoint"), sales of Octyldent(R) and
Nexaband(R) products, and license and product development revenues from
marketing partners. On September 30, 1996, the Company completed its initial
public offering, issuing 2,550,000 shares of Common Stock and generating net
proceeds of approximately $17.9 million. On April 2, 1997, the Company completed
a follow-on public offering, issuing 1,025,000 shares of Common Stock and
generating net proceeds of approximately $12.0 million.

The Company has been unprofitable since its inception and has incurred net
losses in each year, including a net loss of approximately $4.8 million for the
year ended December 31, 1998. The Company anticipates that its recurring
operating expenses will increase for the next several years, as it expects its
research and development and general and administrative expenses to increase in
order to develop new products, manufacture in commercial quantities and fund
additional clinical trials. The Company also expects to incur additional capital
expenditures to expand its manufacturing capabilities. The Company may incur a
loss in 1999 and subsequent years, although the amount of future net losses and
time required by the Company to reach profitability are highly uncertain. The
Company's ability to generate significant revenue and become profitable will
depend on its success in commercializing DERMABOND, expanding its manufacturing
capabilities, developing new products and entering into additional marketing
agreements and on the ability of its marketing partners to commercialize
successfully products incorporating the Company's technologies. No assurance can
be given that the Company will generate significant revenue or become profitable
on a sustained basis, if at all.

On August 28, 1998, the Company was granted approval from the U.S. Food and Drug
Administration ("FDA") of its premarket approval application to market DERMABOND
in the United States. DERMABOND, which is used to replace sutures, staples and
adhesive strips for closing certain topical



                                       8
<PAGE>


incisions and lacerations, is the first such product to be approved by the FDA
for the U.S. market. In March 1996, Closure licensed exclusive worldwide
marketing and distribution rights for DERMABOND to Ethicon, Inc. ("Ethicon") , a
subsidiary of Johnson & Johnson. In August 1997, Closure received CE Mark
approval allowing the Company to ship DERMABOND to Ethicon to support its launch
in European Union countries. DERMABOND is currently marketed by Ethicon in the
U.S. and approximately 26 countries outside the U.S.

RESULTS OF OPERATIONS

Total revenues consisting of product sales only were $3.8 million for the three
months ended March 31, 1999, compared to $770,000 for the three months ended
March 31, 1998. The increase in 1998 product sales was primarily a result of
increased sales volume of DERMABOND.

Cost of products sold were approximately $1.2 million for the three months ended
March 31, 1999, compared to $534,000 for the three months ended March 31, 1998.
Cost of products sold as a percentage of product sales decreased to 31% in the
three months ended March 31, 1999, compared to 69% during the same period of
1998. The decrease in cost of products sold as a percentage of product sales was
primarily a result of the increased sales volume of DERMABOND resulting in the
fixed portion of cost of products sold being allocated over higher sales volume.

Operating expenses were approximately $3.4 million for the three months ended
March 31, 1999, compared to $2.5 million for the three months ended March 31,
1998. This increase was primarily attributable to the addition of personnel,
expansion of the Company's facilities and increased research and development and
regulatory affairs expenses. At March 31, 1999, the Company had approximately 98
employees compared to approximately 65 at March 31, 1998. In March 1998, the
Company relocated its corporate offices into a 50,000 square foot facility and
its manufacturing operations to the same facility in August 1998. Prior to the
move, the Company occupied approximately 20,000 square feet. The increase in
research and development and regulatory affairs expenses was primarily due to
costs associated with the Company's development efforts related to its ongoing
research and development programs. The Company expects these expenses will
increase as the Company expands its pipeline and related development efforts and
clinical trials for potential new products.

Interest expense was $91,000 for the three months ended March 31, 1999, compared
to $88,000 for the three months ended March 31, 1998. This increase was
primarily a result of the Company increasing its borrowings under its term loan
in February 1998.

Investment and interest income was $236,000 for the three months ended March 31,
1999, compared to $354,000 for the same period of 1998. This decrease was
attributed to interest earned from lower average cash and investment balances.

LIQUIDITY AND CAPITAL RESOURCES

The Company has financed its operations to date primarily through the sale of
equity securities, borrowings from Sharpoint and other lenders, license and
product development revenues, and product sales revenues. Through March 31,
1999, the Company had raised approximately $30 million in equity financing. The
Company has entered into and received approximately $4.5 million from a lease
line and term loan since March 1997. In addition, the Company has received
approximately $7.0 million related to the supply and distribution agreement for
DERMABOND entered into with Ethicon in March 1996, of which $2.0 million was
classified as deferred revenue and will be credited against future royalties and
product purchases expected to be paid by Ethicon. The supply and distribution
agreement for DERMABOND does not provide for any additional future milestone
payments from Ethicon.

As of March 31, 1999, the Company had $13.8 million in cash, cash equivalents
and short-term investments, a decrease of $2.9 million from December 31, 1998.
Net working capital was approximately $10.7 million as of March 31, 1999, a
decrease of approximately $900,000 over net working capital available at
December 31, 1998. These decreases were primarily attributable to a reduction in
accounts payable and other liabilities as well as an increase in accounts
receivable.


                                       9
<PAGE>

Net cash provided by investing activities was $1.7 million for the three months
ended March 31, 1999 compared to net cash used for investing activities of $2.6
million for the same period in 1998. The decrease in cash used by investing
activities during the 1999 period was primarily related to decreased purchases
of capital equipment. During the three months ended March 31, 1998 the Company
added leasehold improvements related to the Company's new 50,000 square foot
facility and acquisition of capital equipment.

Net cash provided by financing activities was $20,000 and $1.5 million for the
three months ended March 31, 1999 and 1998, respectively. The Company's primary
financing activity during the three months ended March 31, 1999 was the net
proceeds from exercises of employee stock options. During the same period in
1998, the Company's primary financing activity was the Company's additional
borrowings of $1.5 million under its term loan.

The Company believes that existing cash and cash equivalents and investments,
which totaled approximately $13.8 million at March 31, 1999, will be sufficient
to finance its capital requirements for at least 12 months. The Company may
incur a loss in 1999 and subsequent years, although the amount of future net
losses and time required by the Company to reach profitability are highly
uncertain. The Company anticipates that its recurring operating expenses will
increase for the next several years, as it expects its research and development
and general and administrative expenses to increase in order to develop new
products, manufacture in commercial quantities and fund additional clinical
trials. The Company also expects to incur additional capital expenditures to
expand its manufacturing capabilities.

The Company's future capital requirements, however, will depend on numerous
factors, including (i) the Company's ability to manufacture and commercialize
successfully its lead product, DERMABOND, (ii) the progress of its research and
product development programs for future nonabsorbable and absorbable products,
including clinical studies, (iii) the effectiveness of product commercialization
activities and marketing agreements for its future products, including
additional scale-up of manufacturing capability in anticipation of product
commercialization and development and progress of sales and marketing efforts,
(iv) the ability of the Company to maintain existing marketing agreements,
including its agreement with Ethicon for DERMABOND, and establish and maintain
new marketing agreements, (v) the costs involved in preparing, filing,
prosecuting, defending and enforcing intellectual property rights and complying
with regulatory requirements, (vi) the effect of competing technological and
market developments, (vii) timely receipt of regulatory clearances and approvals
and (viii) general economic conditions. There can be no assurance that the
Company will not be required to seek additional capital to finance its
operations in the future. If the Company's currently available funds and
internally generated cash flow are not sufficient to satisfy its financing
needs, the Company will be required to seek additional funding through bank
borrowings and additional public or private sales of its securities, including
equity securities, or through other arrangements with marketing partners. Other
than the Company's equipment financing line of credit and term loan, the Company
has no credit facility or other committed sources of capital. There can be no
assurance that additional funds, if required, will be available to the Company
on favorable terms, if at all.

YEAR 2000 UPDATE

The Company's Year 2000 Project ("Project") is addressing the issue of computer
programs with date-sensitive software that may be unable to distinguish between
the year 1900 and the year 2000. Failure to correct the Year 2000 Issue could
result in a system failure or miscalculations causing disruptions of operations,
including, among other things, a temporary inability to process transactions,
send invoices, or engage in similar normal business activities. The Company
believes it has identified the significant internal issues and has developed a
plan to resolve these Year 2000 Issues. The Project continues to assess external
customers and suppliers and their Year 2000 compliance.



                                       10
<PAGE>

Based on a recent third party assessment, it appears the Company will be
required to modify or replace insignificant portions of its software so that its
computer systems will properly utilize dates beyond December 31, 1999 and
mitigate the Year 2000 Issue. However, if such modifications and conversions are
not made, or are not completed timely, the Year 2000 Issue could have a material
impact on the operations of the Company.

The Company is in the process of identifying and prioritizing critical suppliers
and customers, and communicating with them about their plans and progress in
addressing the Year 2000 Issue. Therefore, based on presently available
information, there can be no guarantee that the systems of other companies on
which the Company's systems rely will be converted, or if so, in a timely
manner, and that such companies failure to achieve Year 2000 compliance would
not have a material adverse effect on the Company. All critical suppliers and
customers are reporting significant progress toward completion or completion of
projects designed to address their own Year 2000 issues. All have reported plans
to mitigate any Y2K-related disruption by the end of 1999.

The Company has and will continue to utilize both internal and external
resources to mitigate the Year 2000 Issue. The Project is significantly
complete. The total cost associated to mitigate the Year 2000 Issue is not
expected to be material to the Company's financial position, results of
operations or liquidity. To date the Company has incurred and expensed
approximately $60,000 related to the assessment of, and efforts in connection
with, the Project. The total remaining cost of the Project is estimated to be
approximately $15,000 and will be expensed as incurred.

The costs of and the date on which the Company plans to complete the Project are
based on management's best estimates, which were derived utilizing numerous
assumptions and factors, including those of external sources. Therefore, there
can be no guarantee that these estimates will be achieved and actual results
could differ materially from current plans.


ITEM 3.  QUANTITATIVE AND QUALITATIVE DISCLOSURE ABOUT MARKET RISK

INTEREST RATE SENSITIVITY

        The Company is subject to interest rate risk on its investment portfolio
which consists primarily of high quality U.S. government securities, corporate
bonds and Eurodollar bonds with an average maturity of less than one year. The
Company mitigates default risk by investing in what it believes are the safest
and highest credit quality securities and by monitoring the credit rating of
investment issuers. The portfolio includes only marketable securities with
active secondary or resale markets to ensure portfolio liquidity and there are
limitations regarding average and individual duration of investments. These
available-for-sale securities are subject to interest rate risk and will
decrease in value if market interest rates increase. At March 31, 1999, the
Company's total portfolio consisted of approximately $13.3 million of
investments, all of which had maturities within one year. Additionally, the
Company generally has the ability to hold fixed income investments to maturity.
Therefore, the Company does not expect its results of operations or cash flows
to be materially affected due to a sudden change in interest rates.

FOREIGN CURRENCY EXCHANGE RISK

The Company's international sales and related royalties of DERMABOND are based
on sales in foreign currencies, but payable in U.S. dollars, and thus may be
adversely affected by fluctuations in currency exchange rates. Additionally,
fluctuations in currency exchange rates may adversely affect demand for the
Company's products by increasing the price of the Company's products in the
currency of the countries in which the products are sold.



                                       11
<PAGE>


                           PART II: OTHER INFORMATION

ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K.

(a)            Exhibits.
               11     Computation of net loss per share (see Note 5 to Notes to
                      Financial Statements in Item 1 of Part I of this Form
                      10-Q).

               27     Financial Data Schedule.

(b)            Reports on Form 8-K.
               None.



                                       12
<PAGE>

                                   SIGNATURES


Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                         CLOSURE MEDICAL CORPORATION



Date: May 13, 1999          By:\s\ Robert V. Toni
                            ---------------------------------
                                  Robert V. Toni
                                  President and Chief Executive Officer



Date: May 13, 1999          By:\s\ J. Blount Swain
                            ---------------------------------
                                   J. Blount Swain
                                   Vice President and Chief Financial Officer
                                   (Principal Financial and Accounting Officer)



<PAGE>



                                  EXHIBIT INDEX


EXHIBIT
NUMBER       DESCRIPTION
------       -----------

11           Computation of Net Loss Per Share.

27           Financial Data Schedule.