Exhibit 4.1


 


SUBSCRIPTION AGREEMENT


 


SUBSCRIPTION AGREEMENT
(this “Agreement”) made as of the last date set forth on the signature page hereof between Avalon GloboCare
Corp., a Delaware corporation (the “Company”), and the undersigned (the “Subscriber”).


 


W I T N E S S E T H:


 


WHEREAS, the Company
is conducting a private offering (the “Offering”) consisting of up to 3,430,000 shares (the “Shares”)
of common stock, $0.0001 par value per share (“Common Stock”), pursuant to Section 4(a)(2) of the Securities
Act of 1933, as amended (the “Securities Act”) and/or Rule 506 promulgated thereunder; and


 


WHEREAS, the Subscriber
desires to purchase that number of Shares set forth on the signature page hereof on the terms and conditions hereinafter set forth.


 


NOW, THEREFORE, in consideration
of the premises and the mutual representations and covenants hereinafter set forth, the parties hereto do hereby agree as follows:


 


		I.	SUBSCRIPTION FOR SHARES AND REPRESENTATIONS AND COVENANTS BY SUBSCRIBER



 


1.1       Subject to the terms and conditions
hereinafter set forth, the Subscriber hereby irrevocably subscribes for and agrees to purchase from the Company such number of
Shares, and the Company agrees to sell to the Subscriber as is set forth on the signature page hereof, at a per share price equal
to $1.75 per Share. The purchase price is payable by check or by wire transfer of immediately available funds pursuant to the Company's
wire instructions provided upon request. The date of the payment for the Shares by check or by wire transfer shall be referred
to as the Closing Date.


 


1.2       The
Subscriber recognizes that the purchase of the Shares involves a high degree of risk including, but not limited to, the following:
(a) the Company has limited operating history and requires substantial funds in addition to the proceeds of the Offering; (b) an
investment in the Company is highly speculative, and only investors who can afford the loss of their entire investment should consider
investing in the Company and the Shares; (c) the Subscriber may not be able to liquidate its investment; (d) transferability of
the Shares is extremely limited; (e) in the event of a disposition, the Subscriber could sustain the loss of its entire investment;
(f) the Company has not paid any dividends since its inception and does not anticipate paying any dividends; and (g) the Company
may issue additional securities in the future which have rights and preferences that are senior to those of the Common Stock. The
Subscriber represents that the Subscriber has carefully reviewed the risk factors described in the Company's filings made under
the Securities Exchange Act of 1934, as amended.


 






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1.3       The
Subscriber has carefully read the Form 10-K Current Report as filed with the Securities and Exchange Commission (the “SEC”)
on March 13, 2018 (the “Report”), which is attached hereto as Exhibit A, as well as all other filings
made by the Company with the SEC, and the risk factors contained in the Report and the additional risk factors set forth on Exhibit
B, (the “Risk Factors”). The Subscriber has been given the opportunity to ask questions of, and receive
answers from, the Company concerning the terms and conditions of this Offering, the Report and the Risk Factors and to obtain such
additional information, to the extent the Company possesses such information or can acquire it without unreasonable effort or expense,
necessary to verify the accuracy of same as the Subscriber reasonably desires in order to evaluate the investment. The Subscriber
understands the Report and the Risk Factors, and the Subscriber has had the opportunity to discuss any questions regarding any
of the disclosure in the Report and the Risk Factors with his counsel or other advisor. Notwithstanding the foregoing, the only
information upon which the Subscriber has relied is that set forth in the Report and the Risk Factors. The Subscriber has received
no representations or warranties from the Company, its employees, agents or attorneys, in making this investment decision other
than as set forth in the Report and the Risk Factors.


 


1.4       The
Subscriber represents that the Subscriber is an “accredited investor” as such term is defined in Rule 501 of Regulation
D (“Regulation D”) promulgated under the Securities Act, as indicated by the Subscriber’s responses to
the questions contained in Accredited Investor Questionnaire attached hereto as Exhibit C, and that the Subscriber is able
to bear the economic risk of an investment in the Shares.


 


1.5       The
Subscriber hereby acknowledges and represents that (a) the Subscriber has knowledge and experience in business and financial matters,
prior investment experience, including investment in securities that are non-listed, unregistered and/or not traded on a national
securities exchange nor on the NASDAQ, or the Subscriber has employed the services of a “purchaser representative”
(as defined in Rule 501 of Regulation D), attorney and/or accountant to read all of the documents furnished or made available by
the Company both to the Subscriber and to all other prospective investors in the Shares to evaluate the merits and risks of such
an investment on the Subscriber’s behalf; (b) the Subscriber recognizes the highly speculative nature of this investment;
and (c) the Subscriber is able to bear the economic risk that the Subscriber hereby assumes.


 


1.6       The
Subscriber hereby acknowledges receipt and careful review of this Agreement, including all exhibits thereto including the Report
and the Risk Factors, and any documents which may have been made available upon request as reflected therein (collectively referred
to as the “Offering Materials”) and hereby represents that the Subscriber has been furnished by the Company
during the course of the Offering with all information regarding the Company, the terms and conditions of the Offering and any
additional information that the Subscriber has requested or desired to know, and has been afforded the opportunity to ask questions
of and receive answers from duly authorized officers or other representatives of the Company concerning the Company and the terms
and conditions of the Offering.


 


 1.7       (a)       In making the decision
to invest in the Shares the Subscriber has relied solely upon the information provided by the Company in the Offering Materials.
To the extent necessary, the Subscriber has retained, at its own expense, and relied upon appropriate professional advice regarding
the investment, tax and legal merits and consequences of this Agreement and the purchase of the Shares hereunder. The Subscriber
disclaims reliance on any statements made or information provided by any person or entity in the course of Subscriber’s consideration
of an investment in the Shares other than the Offering Materials.


 






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(b)       The
Subscriber represents that (i) the Subscriber was contacted regarding the sale of the Shares by the Company (or an authorized agent
or representative thereof) with whom the Subscriber had a prior substantial pre-existing relationship and (ii) no Shares were offered
or sold to it by means of any form of general solicitation or general advertising, and in connection therewith, the Subscriber
did not (A) receive or review any advertisement, article, notice or other communication published in a newspaper or magazine or
similar media or broadcast over television or radio, whether closed circuit, or generally available; or (B) attend any seminar
meeting or industry investor conference whose attendees were invited by any general solicitation or general advertising.


 


1.8       The
Subscriber hereby represents that the Subscriber, either by reason of the Subscriber’s business or financial experience or
the business or financial experience of the Subscriber’s professional advisors (who are unaffiliated with and not compensated
by the Company or any affiliate or selling agent of the Company, directly or indirectly), has the capacity to protect the Subscriber’s
own interests in connection with the transaction contemplated hereby.


 


1.9       The
Subscriber hereby acknowledges that the Offering has not been reviewed by the SEC nor any state regulatory authority since the
Offering is intended to be exempt from the registration requirements of Section 5 of the Securities Act, pursuant to Regulation
D. The Subscriber understands that the Shares have not been registered under the Securities Act or under any state securities or
“blue sky” laws and agrees not to sell, pledge, assign or otherwise transfer or dispose of the Shares unless they are
registered under the Securities Act and under any applicable state securities or “blue sky” laws or unless an exemption
from such registration is available.


 


1.10       The
Subscriber understands that the Shares have not been registered under the Securities Act by reason of a claimed exemption under
the provisions of the Securities Act that depends, in part, upon the Subscriber’s investment intention. In this connection,
the Subscriber hereby represents that the Subscriber is purchasing the Shares for the Subscriber’s own account for investment
and not with a view toward the resale or distribution to others. The Subscriber, if an entity, further represents that it was not
formed for the purpose of purchasing the Shares.


 


1.11       The
Subscriber understands that the Company’s shares of Common Stock quoted on the OTC Markets and that there is a limited market
for the Common Stock. The Subscriber understands that even if a public market develops for the Common Stock, Rule 144 (“Rule
144”) promulgated under the Securities Act requires for non-affiliates, among other conditions, a holding period prior
to the resale (in limited amounts) of securities acquired in a non-public offering without having to satisfy the registration requirements
under the Securities Act. The Subscriber understands and hereby acknowledges that the Company is under no obligation to register
any of the Shares under the Securities Act or any state securities or “blue sky” laws. The Subscriber understands that
the Company must be current under the 1934 Act for the Subscriber to take advantage of Rule 144.


 






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1.12       Intentionally
Left Blank.


 


1.13       Lock-up
Agreement. The Subscriber agrees that it shall not transfer, offer, pledge, sell, contract to sell, grant any options for the
sale of, assign or otherwise dispose of, directly or indirectly, any of the Shares held by the Subscriber for a period of one year
from the Closing Date. If requested by an underwriter of Common Stock, Subscriber will reaffirm the agreement set forth in this
Section 1.13 in a separate writing in a form satisfactory to such underwriter. The Company may impose stop-transfer instructions
with respect to the Shares. The Subscriber may sell its shares in a private transaction only in the event that such purchaser agrees
to be bound by the terms of this Agreement including this Section 1.13.


 


1.14       The
Subscriber consents to the placement of a legend on any certificate or other document evidencing the Shares that such securities
have not been registered under the Securities Act or any state securities or “blue sky” laws and setting forth or referring
to the restrictions on transferability and sale thereof contained in this Agreement. The Subscriber is aware that the Company will
make a notation in its appropriate records with respect to the restrictions on the transferability of such Shares. The legend to
be placed on each certificate shall be in form substantially similar to the following:


 


“THE
SHARES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”)
OR ANY STATE SECURITIES OR “BLUE SKY LAWS,” AND MAY NOT BE OFFERED, SOLD, TRANSFERRED, ASSIGNED, PLEDGED OR HYPOTHECATED
ABSENT AN EFFECTIVE REGISTRATION THEREOF UNDER SUCH ACT OR COMPLIANCE WITH RULE 144 PROMULGATED UNDER SUCH ACT, OR UNLESS THE COMPANY
HAS RECEIVED AN OPINION OF COUNSEL, REASONABLY SATISFACTORY TO THE COMPANY AND ITS COUNSEL, THAT SUCH REGISTRATION IS NOT REQUIRED.THE
SHARES REPRESENTED BY THIS CERTIFICATE MAY NOT BE OFFERED, SOLD, PLEDGED, TRANSFERRED, ASSIGNED OR OTHERWISE DISPOSED OF EXCEPT
IN ACCORDANCE WITH THE REQUIREMENTS OF THAT CERTAIN SUBSCRIPTION AGREEMENT DATED AS OF _________ __, 2018, A COPY OF WHICH AGREEMENT
THE COMPANY WILL FURNISH, WITHOUT CHARGE, TO THE HOLDER OF THIS CERTIFICATE UPON WRITTEN REQUEST THEREFOR.”


 


The Company, at its discretion, may cause
a stop transfer order to be placed with its transfer agent(s) with respect to the certificates representing the Shares.


 


1.15       The
Subscriber understands that the Company will review this Agreement and is hereby given authority by the Subscriber to call Subscriber’s
bank or place of employment or otherwise review the financial standing of the Subscriber; and it is further agreed that the Company,
at its sole discretion, reserves the unrestricted right, without further documentation or agreement on the part of the Subscriber,
to reject or limit any subscription, to accept subscriptions for fractional Shares and to close the Offering to the Subscriber
at any time and that the Company will issue stop transfer instructions to its transfer agent with respect to such Shares.


 


1.16       The
Subscriber hereby represents that the address of the Subscriber furnished by Subscriber on the signature page hereof is the Subscriber’s
principal residence if Subscriber is an individual or its principal business address if it is a corporation or other entity.


 






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1.17       The
Subscriber represents that the Subscriber has full power and authority (corporate, statutory and otherwise) to execute and deliver
this Agreement and to purchase the Shares. This Agreement constitutes the legal, valid and binding obligation of the Subscriber,
enforceable against the Subscriber in accordance with its terms.


 


1.18       If
the Subscriber is a corporation, partnership, limited liability company, trust, employee benefit plan, individual retirement account,
Keogh Plan, or other tax-exempt entity, it is authorized and qualified to invest in the Company and the person signing this Agreement
on behalf of such entity has been duly authorized by such entity to do so.


 


1.19       The
Subscriber acknowledges that he, she or it are not Registered Representative of a FINRA member firm or a FINRA firm.


 


1.20       The
Subscriber acknowledges that at such time, if ever, as the Shares are registered, sales of the Shares will be subject to state
securities laws.


 


1.21       The
Subscriber agrees not to issue any public statement with respect to the Subscriber’s investment or proposed investment in
the Company or the terms of any agreement or covenant between them and the Company without the Company’s prior written consent,
except such disclosures as may be required under applicable law or under any applicable order, rule or regulation.


 


1.22       The
Subscriber agrees to hold the Company and its directors, officers, employees, affiliates, controlling persons and agents and their
respective heirs, representatives, successors and assigns harmless and to indemnify them against all liabilities, costs and expenses
incurred by them as a result of (a) any sale or distribution of the Shares by the Subscriber in violation of the Securities Act
or any applicable state securities or “blue sky” laws; or (b) any false representation or warranty or any breach or
failure by the Subscriber to comply with any covenant made by the Subscriber in this Agreement (including the Confidential Investor
Questionnaire contained in Article VI herein) or any other document furnished by the Subscriber to any of the foregoing in connection
with this transaction.


 


		II.	REPRESENTATIONS BY AND COVENANTS OF THE COMPANY



 


The Company hereby represents
and warrants to the Subscriber that:


 


2.1         Organization and Qualification. The Company and each of its Subsidiaries, if any, is a corporation duly organized,
validly existing and in good standing under the laws of the jurisdiction in which it is incorporated, with full power and authority
(corporate and other) to own, lease, use and operate its properties and to carry on its business as and where now owned, leased,
used, operated and conducted. “Subsidiary” shall mean any corporation or other entity of which at least a majority
of the securities or other ownership interests having ordinary voting power (absolutely or contingently) for the election of directors
or other persons performing similar functions are at the time owned directly or indirectly by the Company and/or any of its other
Subsidiaries.


 






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2.2         SEC
Documents. The Company has timely filed all reports, schedules, forms, statements and other documents required to be filed
by it with the SEC pursuant to the reporting requirements of the Securities Exchange Act of 1934, as amended (the “1934
Act”) (all of the foregoing filed prior to the date hereof and all exhibits included therein and financial statements
and schedules thereto and documents (other than exhibits to such documents) incorporated by reference therein, being hereinafter
referred to herein as the “Commission Documents”). As of their respective dates, the Commission Documents complied
in all material respects with the requirements of the 1934 Act and the rules and regulations of the SEC promulgated thereunder
applicable to the Commission Documents, and none of the Commission Documents, at the time they were filed with the SEC, contained
any untrue statement of a material fact or omitted to state a material fact required to be stated therein or necessary in order
to make the statements therein, in light of the circumstances under which they were made, not misleading. None of the statements
made in any such Commission Documents is, or has been, required to be amended or updated under applicable law (except for such
statements as have been amended or updated in subsequent filings prior the date hereof). As of their respective dates, the financial
statements of the Company included in the Commission Documents complied as to form in all material respects with applicable accounting
requirements and the published rules and regulations of the SEC with respect thereto. 


 


2.2       Capitalization.
The authorized, issued and outstanding capital stock of the Company is as set forth in the Commission Documents.


 


2.3       Authorization;
Enforcement. The Company has all requisite corporate power and authority to enter into and perform this Agreement and to consummate
the transactions contemplated hereby and thereby and to issue the Common Stock, in accordance with the terms hereof and thereof.
The execution and delivery of this Agreement by the Company and the consummation by it of the transactions contemplated hereby
and thereby have been duly authorized by the Company’s Board of Directors. This Agreement has been duly executed and delivered
by the Company by its authorized representative, and such authorized representative is the true and official representative with
authority to sign this Agreement and the other documents executed in connection herewith and bind the Company accordingly. This
Agreement constitutes, and upon execution and delivery by the Company will constitute, a legal, valid and binding obligation of
the Company enforceable against the Company in accordance with its terms.


 


2.4       Acknowledgment
of Dilution. The Company understands and acknowledges the dilutive effect to the Common Stock upon the issuance of the Shares.


 


2.5       Bad
Actor Representation. None of the Company, any of its predecessors, any affiliated issuer, any director, executive officer,
other officer of the Company participating in the Offering, any beneficial owner of 20% or more of the Company’s outstanding
voting equity securities, calculated on the basis of voting power, nor any promoter (as that term is defined in Rule 405 under
the Securities Act) connected with the Company in any capacity at the time of sale (each, an “Issuer Covered Person”
and, together, “Issuer Covered Persons”) is subject to any of the “Bad Actor” disqualifications
described in Rule 506(d)(1)(i) to (viii) under the Securities Act (a “Disqualification Event”), except for a
Disqualification Event covered by Rule 506(d)(2) or (d)(3). The Company has exercised reasonable care to determine whether any
Issuer Covered Person is subject to a Disqualification Event.


 






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2.6       Actions
Pending. Except as disclosed in the Commission Documents, there is no action, suit, claim, investigation, arbitration, alternate
dispute resolution proceeding or any other proceeding pending or, to the knowledge of the Company, threatened against or involving
the Company, any Subsidiary (i) which questions the validity of this Agreement or any of the other Offering Materials or the transactions
contemplated hereby or thereby or any action taken or to be taken pursuant hereto or thereto or (ii) involving any of their respective
properties or assets. To the knowledge of the Company, there are no outstanding orders, judgments, injunctions, awards or decrees
of any court, arbitrator or governmental or regulatory body against the Company or any Subsidiary or any of their respective executive
officers or directors in their capacities as such.


 


2.7       Compliance
with Law. The Company and its Subsidiaries have all material franchises, permits, licenses, consents and other governmental
or regulatory authorizations and approvals necessary for the conduct of their respective business as now being conducted by it
unless the failure to possess such franchises, permits, licenses, consents and other governmental or regulatory authorizations
and approvals, individually or in the aggregate, could not reasonably be expected to have a Material Adverse Effect.


 


2.8       Compliance.
The Company: (i) is not in default under or in violation of (and no event has occurred that has not been waived that, with notice
or lapse of time or both, would result in a default by the Company), nor has the Company received notice of a claim that it is
in default under or that it is in violation of, any indenture, loan or credit agreement or any other agreement or instrument to
which it is a party or by which it or any of its properties is bound (whether or not such default or violation has been waived),
(ii) is in violation of any judgment, decree or order of any court, arbitrator or other governmental authority or (iii) is or has
been in violation of any statute, rule, ordinance or regulation of any governmental authority, including without limitation all
foreign, federal, state and local laws relating to taxes, environmental protection, occupational health and safety, product quality
and safety and employment and labor matters, except in each case as could not have or reasonably be expected to result in a Material
Adverse Effect. For the purposes of this Agreement, “Material Adverse Effect” means any of (i) a material and
adverse effect on the legality, validity or enforceability of this Agreement or the other Offering Materials, (ii) a material adverse
effect on the business, operations, properties, or financial condition of the Company, its Subsidiaries, individually, or in the
aggregate and/or any condition, circumstance, or situation that would prohibit or otherwise materially interfere with the ability
of the Company to perform any of its obligations under this Agreement or the other Offering Materials in any material respect or
(iii) an adverse impairment to the Company’s ability to perform on a timely basis its obligations under this Agreement.


 


2.9       No
Violation. The execution, delivery and performance of this Agreement by the Company and the consummation by the Company of
the transactions contemplated herein and therein do not and will not (i) violate any provision of the Articles or Bylaws, (ii)
conflict with, or constitute a default (or an event which with notice or lapse of time or both would become a default) under, or
give to others any rights of termination, amendment, acceleration or cancellation of, any agreement, mortgage, deed of trust, indenture,
note, bond, license, lease agreement, instrument or obligation to which the Company or any Subsidiary is a party or by which it
or its properties or assets are bound, (iii) create or impose a lien, mortgage, security interest, pledge, charge or encumbrance
(collectively, “Lien”) of any nature on any property of the Company or any Subsidiary under any agreement or
any commitment to which the Company or any Subsidiary is a party or by which the Company, or any Subsidiary is bound or by which
any of its respective properties or assets are bound, or (iv) result in a violation of any federal, state, local or foreign statute,
rule, regulation, order, judgment or decree (including federal and state securities laws and regulations) applicable to the Company
or any Subsidiary or by which any property or asset of the Company, or any Subsidiary are bound or affected, provided, however,
that, excluded from the foregoing in all cases are such conflicts, defaults, terminations, amendments, accelerations, cancellations
and violations as would not, individually or in the aggregate, have a Material Adverse Effect.


 






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2.10       No
Conflicts. The execution, delivery and performance of this Agreement and the Offering Materials by the Company and the consummation
by the Company of the transactions contemplated herein and therein do not and will not (i) violate any provision of the Articles
or Bylaws, (ii) conflict with, or constitute a default (or an event which with notice or lapse of time or both would become a default)
under, or give to others any rights of termination, amendment, acceleration or cancellation of, any agreement, mortgage, deed of
trust, indenture, note, bond, license, lease agreement, instrument or obligation to which the Company or any Subsidiary is a party
or by which it or its properties or assets are bound, (iii) create or impose a lien, mortgage, security interest, pledge, charge
or encumbrance (collectively, “Lien”) of any nature on any property of the Company or any Subsidiary under any agreement
or any commitment to which the Company or any Subsidiary is a party or by which the Company, or any Subsidiary is bound or by which
any of its respective properties or assets are bound, or (iv) result in a violation of any federal, state, local or foreign statute,
rule, regulation, order, judgment or decree (including federal and state securities laws and regulations) applicable to the Company
or any Subsidiary or by which any property or asset of the Company, or any Subsidiary are bound or affected, provided, however,
that, excluded from the foregoing in all cases are such conflicts, defaults, terminations, amendments, accelerations, cancellations
and violations as would not, individually or in the aggregate, have a Material Adverse Effect.


 


2.11       Private
Placement and Solicitation. Assuming the accuracy of the Subscribers’ representations and warranties set forth in Section
1, no registration under the Securities Act is required for the offer and sale of the Common Stock by the Company to the Subscribers
as contemplated hereby. Based in part on the accuracy of the representations of the Subscribers in Section 1, and subject to timely
applicable Form D filings pursuant to Regulation D of the Securities Act with the SEC and pursuant to applicable state securities
laws, the offer, sale and issuance of the Common Stock to be issued pursuant to and in conformity with the terms of this Agreement,
will be issued in compliance with all applicable federal and state securities laws. Neither the Company nor any of its affiliates,
nor any person acting on its or their behalf, has engaged in any form of general solicitation or general advertising (within the
meaning of Regulation D under the Securities Act) in connection with the offer or sale of any of the Common Stock.


 


2.12       Governmental
Approvals. Except for the filing of any notice prior or subsequent to each closing that may be required under applicable state
and/or federal securities laws (which if required, shall be filed on a timely basis), including the filing of a Form D, no authorization,
consent, approval, license, exemption of, filing or registration with any court or governmental department, commission, board,
bureau, agency or instrumentality, domestic or foreign, is or will be necessary for, or in connection with, the execution or delivery
of the Common Stock, or for the performance by the Company of its obligations under this Agreement and the Offering Materials.


 






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2.13       Investment
Company. The Company is not an “investment company” within the meaning of such term under the Investment Company
Act of 1940, as amended, and the rules and regulations of the SEC thereunder.


 


2.14       Use
of Proceeds. The Company shall use the proceeds from the sale of the Common Stock for working capital purposes, provided, however,
the Company may use up to $1,000,000 in connection with the repayment of DOING (as defined below) The Company entered into and
closed a Subscription Agreement with an accredited investor (the “March 2017 Accredited Investor”) pursuant to which
the March 2017 Accredited Investor purchased 3,000,000 shares of the Company’s common stock (“March 2017 Shares”)
for a purchase price of $3,000,000 (the “Purchase Price”). The closing occurred on March 3, 2017. The Company, Avalon
(Shanghai) Healthcare Technology Co., Ltd. (“Avalon Shanghai”), Beijing DOING Biomedical Technology Co., Ltd. (“DOING”)
and the March 2017 Accredited Investor entered into a Share Subscription Agreement whereby the parties acknowledged, among other
things, that DOING agreed to transfer the Purchase Price to Avalon Shanghai on behalf of the March 2017 Investor and the March
2017 Accredited Investor agreed to transfer the March 2017 Shares to DOING upon DOING completing the registration of the acquisition
of the March 2017 Shares with the Beijing Commerce Commission (“BCC”) and obtaining an Enterprise Overseas Investment
Certificate (the “Investment Certificate”) from BCC. If DOING fails to complete the registration and acquire the Investment
Certificate within one year of the closing then Avalon Shanghai shall transfer $3,000,000 with interest of 20% to DOING upon the
request of DOING (the “BCC Repayment Obligation”). As of the date hereof, the Company is obligated to DOING in the
principal amount of $3,000,000. The Company is presently in negotiations to make a payment in the amount of $1,000,000 to DOING
and convert the balance of the amount owed to DOING into promissory note. There is no guarantee that the Company will be able to
successfully finalize this restructuring with DOING. In the event the Company is successful, the Company will use $1,000,000 of
the proceeds from this Offering as partial repayment of DOING.


 


2.15       Securities
Compliance. The Company shall notify the SEC in accordance with its rules and regulations, of the transactions contemplated
by this Agreement and the Offering Materials, including filing a Form D with respect to the Common Stock, as required under Regulation
D and applicable “blue sky” laws if such Common Stock is offered pursuant to Rule 506 of Regulation D and shall take
all other necessary action and proceedings as may be required and permitted by applicable law, rule and regulation, for the legal
and valid issuance of the Common Stock to the Subscribers.


 


2.16       No
Integrated Offerings. The Company shall not make any offers or sales of any security (other than the securities being offered
or sold hereunder) under circumstances that would require registration of the securities being offered or sold hereunder under
the Securities Act.


 






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2.17       No
Brokers.  The Company has taken no action which would give rise to any claim by any person for brokerage commissions,
transaction fees or similar payments relating to this Agreement or the transactions contemplated hereby, other than the payment
of a fee in accordance with the placement agent agreement with Boustead Securities dated October 26, 2017 which includes (i) the
payment of seven percent (7%) of the gross proceeds of the Offering, for a maximum amount of sales commissions of $420,175 based
on the sale of all of the Shares and (ii) a warrant to purchase a number of shares equal to seven percent (7%) of the
gross proceeds received by the Company from the Offering, divisible by and exercisable at a strike price equal to one hundred
percent (100%) of the fair market value of the Common Stock for the Company as of the date of the closing of the Offering, in
whole or in part, at any time within five (5) years from issuance. 


 


		III.	TERMS OF SUBSCRIPTION



 


3.1       All
funds shall be submitted directly to the Company’s account as set forth on Section 1.1 hereof.


 


3.2       Certificates
representing the Common Stock purchased by the Subscriber pursuant to this Agreement will be prepared for delivery to the Subscriber
within 15 business days following the closing, the timing of which is at the Company’s sole discretion, at which such purchase
takes place. The Subscriber hereby authorizes and directs the Company to deliver the certificates representing the Common Stock
purchased by the Subscriber pursuant to this Agreement directly to the Subscriber’s residential or business address indicated
on the signature page hereto.


 


		IV.	CONDITIONS TO OBLIGATIONS OF THE SUBSCRIBERS



 


4.1       The
Subscriber’s obligation to purchase the Shares at the closing at which such purchase is to be consummated is subject to the
fulfillment on or prior to such closing of the following conditions, which conditions may be waived at the option of each Subscriber
to the extent permitted by law:


 


(a)        Covenants. All covenants, agreements and conditions contained in this Agreement to be performed by the Company on
or prior to the date of such closing shall have been performed or complied with in all material respects.


 


(b)        No Legal Order Pending. There shall not then be in effect any legal or other order enjoining or restraining the transactions
contemplated by this Agreement.


 


(c)        No Law Prohibiting or Restricting Such Sale. There shall not be in effect any law, rule or regulation prohibiting
or restricting such sale or requiring any consent or approval of any person, which shall not have been obtained, to issue the Shares
(except as otherwise provided in this Agreement).


 






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		V.	MISCELLANEOUS



 


5.1       Any
notice or other communication given hereunder shall be deemed sufficient if in writing and sent by registered or certified mail,
return receipt requested, or delivered by hand against written receipt therefor, addressed as follows:


 


if to the
Company, to it at:


 


	Avalon GloboCare Corp.
	4400 Route 9 South, Suite 3100
	Freehold, New Jersey 07728
	Attention: David Jin
	Telephone: (646) 762-4517
	
        Facsimile:

         



with a copy to: 


 


Fleming PLLC 


30 Wall Street, 8th Floor 


New York, New York 10005 


Attention: Stephen Fleming, Esq. 


Telephone: (516) 833-5034 


Facsimile: (516) 977-1209 


Email: smf@flemingpllc.com


 


if to the Subscriber, to the Subscriber’s
address indicated on the signature page of this Agreement.


 


Notices shall be deemed to have been given
or delivered on the date of mailing, except notices of change of address, which shall be deemed to have been given or delivered
when received.


 


5.2       Except
as otherwise provided herein, this Agreement shall not be changed, modified or amended except by a writing signed by the parties
to be charged, and this Agreement may not be discharged except by performance in accordance with its terms or by a writing signed
by the party to be charged.


 


5.3       Subject
to the provisions of Section 5.10, this Agreement shall be binding upon and inure to the benefit of the parties hereto and to their
respective heirs, legal representatives, successors and assigns. This Agreement sets forth the entire agreement and understanding
between the parties as to the subject matter hereof and merges and supersedes all prior discussions, agreements and understandings
of any and every nature among them.


 


5.4       Upon
the execution and delivery of this Agreement by the Subscriber, this Agreement shall become a binding obligation of the Subscriber
with respect to the purchase of Shares as herein provided, subject, however, to the right hereby reserved by the Company to enter
into the same agreements with other subscribers and to add and/or delete other persons as subscribers.


 






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5.5       NOTWITHSTANDING
THE PLACE WHERE THIS AGREEMENT MAY BE EXECUTED BY ANY OF THE PARTIES HERETO, THE PARTIES EXPRESSLY AGREE THAT ALL THE TERMS AND
PROVISIONS HEREOF SHALL BE CONSTRUED IN ACCORDANCE WITH AND GOVERNED BY THE LAWS OF THE STATE OF NEW JERSEY WITHOUT REGARD TO SUCH
STATE’S PRINCIPLES OF CONFLICTS OF LAW. IN THE EVENT THAT A JUDICIAL PROCEEDING IS NECESSARY, THE SOLE FORUM FOR RESOLVING
DISPUTES ARISING OUT OF OR RELATING TO THIS AGREEMENT IS THE COURTS STATE OF NEW JERSEY IN AND FOR THE COUNTY OF MONMOUTH OR THE
FEDERAL COURTS FOR SUCH STATE AND COUNTY, AND ALL RELATED APPELLATE COURTS, THE PARTIES HEREBY IRREVOCABLY CONSENT TO THE JURISDICTION
OF SUCH COURTS AND AGREE TO SAID VENUE.


 


5.6       In
order to discourage frivolous claims the parties agree that unless a claimant in any proceeding arising out of this Agreement succeeds
in establishing his claim and recovering a judgment against another party (regardless of whether such claimant succeeds against
one of the other parties to the action), then the other party shall be entitled to recover from such claimant all of its/their
reasonable legal costs and expenses relating to such proceeding and/or incurred in preparation therefor.


 


5.7       The
holding of any provision of this Agreement to be invalid or unenforceable by a court of competent jurisdiction shall not affect
any other provision of this Agreement, which shall remain in full force and effect. If any provision of this Agreement shall be
declared by a court of competent jurisdiction to be invalid, illegal or incapable of being enforced in whole or in part, such provision
shall be interpreted so as to remain enforceable to the maximum extent permissible consistent with applicable law and the remaining
conditions and provisions or portions thereof shall nevertheless remain in full force and effect and enforceable to the extent
they are valid, legal and enforceable, and no provisions shall be deemed dependent upon any other covenant or provision unless
so expressed herein.


 


5.8       It
is agreed that a waiver by either party of a breach of any provision of this Agreement shall not operate, or be construed, as a
waiver of any subsequent breach by that same party.


 


5.9       The
parties agree to execute and deliver all such further documents, agreements and instruments and take such other and further action
as may be necessary or appropriate to carry out the purposes and intent of this Agreement.


 


5.10       This
Agreement may be executed in two or more counterparts each of which shall be deemed an original, but all of which shall together
constitute one and the same instrument.


 


5.11       Nothing
in this Agreement shall create or be deemed to create any rights in any person or entity not a party to this Agreement.


 


[REMAINDER OF PAGE INTENTIONALLY LEFT
BLANK]


 




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NUMBER OF SHARES
_________ X $1.75 = $______ (the “Purchase Price”)


 





	 	 	 
	Signature	 	Signature (if purchasing jointly)
	 	 	 
	 	 	 
	Name Typed or Printed	 	Name Typed or Printed
	 	 	 
	 	 	 
	Title (if Subscriber is an Entity)	 	Title (if Subscriber is an Entity)
	 	 	 
	 	 	 
	Entity Name (if applicable)	 	Entity Name (if applicable
	 	 	 
	 	 	 
	 	 	 
	 	 	 
	Address	 	Address
	 	 	 
	 	 	 
	City, State and Zip Code	 	City, State and Zip Code
	 	 	 
	 	 	 
	Telephone-Business	 	Telephone-Business
	 	 	 
	 	 	 
	Telephone-Residence	 	Telephone-Residence
	 	 	 
	 	 	 
	Facsimile-Business	 	Facsimile-Business
	 	 	 
	 	 	 
	Facsimile-Residence	 	Facsimile-Residence
	 	 	 
	 	 	 
	Tax ID # or Social Security #	 	Tax ID # or Social Security #
	 	 	 
	Name in which securities should be issued:	 	 





 


Dated:            _________,
2018 


 


This Subscription Agreement
is agreed to and accepted as of ________________ , 2018.


 





	 	AVALON GLOBOCARE CORP.
	 	 	 
	 	By:	 
	 	Name:  David Jin
	 	Title:    Chief Executive Officer



 




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CERTIFICATE OF SIGNATORY 


 


(To be completed if Securities are 


being subscribed for by an entity) 


 


I, ____________________________, am the
____________________________ of





 


__________________________________________
(the “Entity”). 


 


I certify that I am empowered and duly
authorized by the Entity to execute and carry out the terms of the Subscription Agreement and to purchase and hold the shares
of Common Stock, and certify further that the Subscription Agreement has been duly and validly executed on behalf of the Entity
and constitutes a legal and binding obligation of the Entity. 


 


IN WITNESS WHEREOF, I have set my hand
this ________ day of _________________, 2018  


 





	 	 	 
	 	(Signature)	 


 




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Exhibit A - Risk Factors


 


Risks Related to this Offering 


 


The offering price
for the Common Stock has been determined by the Company. 


 


The price at which
the Common Stock is being offered has been determined by us based on current sales, sales forecasts and standard corporate valuation
estimation methods. There is no direct relationship between the offering price and our assets, book value, net worth, or any other
economic or recognized criteria of value. 


 


An investment in
the Shares is speculative and there can be no assurance of any return on any such investment. 


 


An investment in the
Shares is speculative and there is no assurance that investors will obtain any return on their investment. Investors will be subject
to substantial risks involved in an investment in the Company, including the risk of losing their entire investment. 


 


We have significant
discretion over certain of the net proceeds. 


 


The maximum gross proceeds
to us from the sale of the Shares will be $3,430,000. The net proceeds of this Offering will be applied to general corporate purposes.
The Company entered into and closed a Subscription Agreement with an accredited investor (the “March 2017 Accredited Investor”)
pursuant to which the March 2017 Accredited Investor purchased 3,000,000 shares of the Company’s common stock (“March
2017 Shares”) for a purchase price of $3,000,000 (the “Purchase Price”). The closing occurred on March 3, 2017.
The Company, Avalon (Shanghai) Healthcare Technology Co., Ltd. (“Avalon Shanghai”), Beijing DOING Biomedical Technology
Co., Ltd. (“DOING”) and the March 2017 Accredited Investor entered into a Share Subscription Agreement whereby the
parties acknowledged, among other things, that DOING agreed to transfer the Purchase Price to Avalon Shanghai on behalf of the
March 2017 Investor and the March 2017 Accredited Investor agreed to transfer the March 2017 Shares to DOING upon DOING completing
the registration of the acquisition of the March 2017 Shares with the Beijing Commerce Commission (“BCC”) and obtaining
an Enterprise Overseas Investment Certificate (the “Investment Certificate”) from BCC. If DOING fails to complete the
registration and acquire the Investment Certificate within one year of the closing then Avalon Shanghai shall transfer $3,000,000
with interest of 20% to DOING upon the request of DOING (the “BCC Repayment Obligation”). As of the date hereof, the
Company is obligated to DOING in the principal amount of $3,000,000. The Company is presently in negotiations to make a payment
in the amount of $1,000,000 to DOING and convert the balance of the amount owed to DOING into promissory note. There is no guarantee
that the Company will be able to successfully finalize this restructuring with DOING. In the event the Company is successful, the
Company will use $1,000,000 of the proceeds from this Offering as partial repayment of DOING.  The use of proceeds may change
as management deems fit. The proceeds shall be used to carry out our business plan, and satisfy all our expenses, foreseeable and
unforeseeable. As is the case with any business, particularly one without a proven business model, it should be expected that certain
expenses unforeseeable to management at this juncture will arise in the future. There can be no assurance that management’s
use of proceeds generated through this Offering will prove optimal or translate into revenue or profitability for the Company.
Investors are urged to consult with their attorneys, accountants and personal investment advisors prior to making any decision
to invest in the Company.


 






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The Maximum Offering
will be offered by on a “Best Efforts” basis, and we may not raise the Maximum offering. 


 


We are offering the
shares with respect to the Maximum Offering. In a best efforts offering such as the one described in this Memorandum, there is
no assurance that we will sell the Maximum Offering. Accordingly, we may close upon amounts less than the Maximum Offering which
may not provide us with sufficient funds to fully implement our business plan.


 




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Exhibit B – Form 10-K Annual Report December 31, 2017


 




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Exhibit C - Accredited Investor Questionnaire 


 


CONFIDENTIAL INVESTOR
QUESTIONNAIRE


 


1.       The
Subscriber represents and warrants that he, she or it comes within one category marked below, and that for any category marked,
he, she or it has truthfully set forth, where applicable, the factual basis or reason the Subscriber comes within that category.
ALL INFORMATION IN RESPONSE TO THIS SECTION WILL BE KEPT STRICTLY CONFIDENTIAL. The undersigned agrees to furnish any additional
information which the Company deems necessary in order to verify the answers set forth below.


 





	Category A __	The undersigned is an individual (not a partnership, corporation, etc.) whose individual net worth, or joint net worth with his or her spouse, presently exceeds $1,000,000.
	 	 
	 	Explanation.  In calculating net worth you may include equity in personal property and real estate (excluding your principal residence), cash, short-term investments, stock and securities.  Equity in personal property and real estate should be based on the fair market value of such property less debt secured by such property.
	 	 
	Category B __	The undersigned is an individual (not a partnership, corporation, etc.) who had an income in excess of $200,000 in each of the two most recent years, or joint income with his or her spouse in excess of $300,000 in each of those years (in each case including foreign income, tax exempt income and full amount of capital gains and losses but excluding any income of other family members and any unrealized capital appreciation) and has a reasonable expectation of reaching the same income level in the current year.
	 	 
	Category C __	The undersigned is a director or executive officer of the Company which is issuing and selling the Shares.
	 	 
	Category D __	The undersigned is a bank; a savings and loan association; insurance company; registered investment company; registered business development company; licensed small business investment company (“SBIC”); or employee benefit plan within the meaning of Title 1 of ERISA and (a) the investment decision is made by a plan fiduciary which is either a bank, savings and loan association, insurance company or registered investment advisor, or (b) the plan has total assets in excess of $5,000,000 or (c) is a self directed plan with investment decisions made solely by persons that are accredited investors. (describe entity)
	 	 
	 	 
	 	 
	Category E __	The undersigned is a private business development company as defined in section 202(a) (22) of the Investment Advisors Act of 1940. (describe entity) 
	 	 
	 	 



 






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	Category F __	The undersigned is either a corporation, partnership, Massachusetts business trust, or non-profit organization within the meaning of Section 501(c) (3) of the Internal Revenue Code, in each case not formed for the specific purpose of acquiring the Shares and with total assets in excess of $5,000,000. (describe entity)
	 	 
	 	 
	 	 
	Category G __	The undersigned is a trust with total assets in excess of $5,000,000, not formed for the specific purpose of acquiring the Shares, where the purchase is directed by a “sophisticated investor” as defined in Regulation 506(b)(2)(ii) under the Act.
	 	 
	Category H __	The undersigned is an entity (other than a trust) in which all of the equity owners are “accredited investors” within one or more of the above categories.  If relying upon this Category alone, each equity owner must complete a separate copy of this Agreement.  (describe entity)
	 	 
	 	 
	 	 
	Category I __	The undersigned is not within any of the categories above and is therefore not an accredited investor.
	 	 
	 	The undersigned agrees that the undersigned will notify the Company at any time on or prior to the closing in the event that the representations and warranties in this Agreement shall cease to be true, accurate and complete.










 


2.       SUITABILITY
(please answer each question)


 


(a)       For
an individual Subscriber, please describe your current employment, including the company by which you are employed and its principal
business:  





	 	 
	 	 
	 	 
	 	 



 


(b)       For
an individual Subscriber, please describe any college or graduate degrees held by you:  


	 	 
	 	 
	 	 
	 	 





 


(c)       For
all Subscribers, please list types of prior investments:  


	 	 
	 	 
	 	 
	 	 





 






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(d)       For
all Subscribers, please state whether you have participated in other private placements before:


 


YES_______                     NO_______


 


(e)       If
your answer to question (d) above was “YES”, please indicate frequency of such prior participation in private placements
of:


 


		
        

        Public 

        Companies 
	 	
        

        Private 

        Companies 
	 	
        Public or Private Companies 

        with no, or insignificant, 

        assets and operations

	 	 	 	 	 	 
	Frequently	 	 	 	 	 
	Occasionally	 	 	 	 	 
	Never	 	 	 	 	 


 


 


(f)       For
individual Subscribers, do you expect your current level of income to significantly decrease in the foreseeable future:


 


YES_______                     NO_______


 


(g)       For
trust, corporate, partnership and other institutional Subscribers, do you expect your total assets to significantly decrease in
the foreseeable future:


 


YES_______                     NO_______


 


(h)       For
all Subscribers, do you have any other investments or contingent liabilities which you reasonably anticipate could cause you to
need sudden cash requirements in excess of cash readily available to you:


 


YES_______                     NO_______


 


(i)       For
all Subscribers, are you familiar with the risk aspects and the non-liquidity of investments such as the securities for which you
seek to subscribe?


 


YES_______                     NO_______


 


(j)       
For all Subscribers, do you understand that there is no guarantee of financial return on this investment and that you run the risk
of losing your entire investment?


 


YES_______                     NO_______


 


3.       MANNER
IN WHICH TITLE IS TO BE HELD. (circle one)


 


(a)       Individual
Ownership 


(b)       Community
Property 


(c)       Joint
Tenant with Right of


Survivorship (both parties


must sign) 


 






    20 


    


    

 


(d)       Partnership* 


(e)       Tenants
in Common 


(f)        Company* 


(g)       Trust* 


(h)       Other*


 


*If Securities are being
subscribed for by an entity, the attached Certificate of Signatory must also be completed.


 


The undersigned is informed of the significance to the Company
of the foregoing representations and answers contained in the Confidential Investor Questionnaire contained in this Article VI
and such answers have been provided under the assumption that the Company will rely on them.


 






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