EXHIBIT
      10.1A




**PROTEIN
      POLYMER TECHNOLOGIES, INC.**


**8%
      SECURED PROMISSORY NOTE**


**DUE
      JULY 12, 2006**


**NOW
      DUE APRIL 10, 2007**


**AMENDMENT
      NO. 5**


**DATED
      APRIL 10, 2007**




On
      April
      13, 2006, Protein Polymer Technologies, Inc., (“Maker”), issued to Matthew J.
      Szulik (“Payee”) a note (the “Note”) in the Principal amount of One Million
      ($1,000,000.00) Dollars pursuant to which, among other things, Maker agreed
      to
      pay the Obligations, as defined therein, to Payee on July 12, 2006, or sooner
      as
      otherwise provided therein. On July 12, 2006, Maker and Taurus Advisory Group,
      LLC, now TAG Virgin Islands, Inc., as agent for Payee, (“Agent”) executed
      Amendment No. 1 to the Note pursuant to which, among other things, “July 12,
      2006” in the first paragraph of the Note was changed to “October 10, 2006.” On
      August 18, 2006, as of July 14, 2006, Maker and Agent executed Amendment No.
      2
      to the Note pursuant to which, among other things, One Million ($1,000,000.00)
      Dollars” was changed to “One Million Five Hundred Thousand ($1,500,000.00)
      Dollars.” On September 29, 2006, Maker and Agent executed Amendment No. 3 to the
      Note pursuant to which, among other things, “One Million Five Hundred Thousand
      ($1,500,000.00) Dollars” was changed to “Two Million Five Hundred Thousand
      ($2,500,000.00) Dollars,” “October 10, 2006” was changed to “January 10, 2007”
and Section 10 (c) of the Note was amended. On January 10, 2007, Maker and
      Agent
      executed Amendment No. 4 to the Note pursuant to which, among other things,
“Two
      Million Five Hundred Thousand ($2,500,000.00) Dollars” was changed to “Four
      Million ($4,000,000.00) Dollars” and “January 10, 2007” was changed to “April
      10, 2007.” In accordance with the terms of Section 10 (f) thereof, the Note is
      hereby amended as follows:




1.  In
      the
      first paragraph (i) “Four Million ($4,000,000.00) Dollars” is changed to “Four
      Million Eight Hundred Thousand ($4,800,000.00) Dollars”; and (ii) “April 10,
      2007” is changed to “August 10, 2007.”




Maker
      shall accrue interest to Payee as follows. (i) 8% per annum on Principal in
      the
      amount of One Million ($1,000,000.00) Dollars from April 12, 2006 through the
      date that all of the Obligations are paid in full; plus (ii) $% per annum on
      Principal in the amount of Five Hundred Thousand ($500,000.00) Dollars from
      July
      14, 2006 through the date that all of the Obligations are paid in full; plus
      (iii) 8% per annum on Principal in the amount of One Million ($1,000,000.00)
      Dollars from September 6, 2006 through the date that all of the Obligations
      are
      paid in full; (iv) 8% per annum on Principal in the amount of Five Hundred
      Thousand ($500,000.00) Dollars from October 25, 2006 through the date that
      all
      of the Obligations are paid in full; plus (v) 8% per annum on Principal in
      the
      amount of Five Hundred Thousand ($500,000.00) Dollars from November 20, 2006
      through the date that all of the Obligations are paid in full; plus (vi) 8%
      per
      annum on Principal in the amount of Five Hundred Thousand ($500,000.00) Dollars
      from January 4, 2007 through the date that all of the Obligations are paid
      in
      full; plus (vii) 8% per annum on Principal in the amount of Five Hundred
      Thousand ($500,000.00) Dollars from









February
      21, 2007 through the date that all of the Obligations are paid in full; plus
      (viii) 8% per annum on Principal in the amount of Two Hundred Thousand
      ($200,000.00) Dollars from march 28, 2007 through the date that all of the
      Obligations are paid in full; plus (ix) 8% per annum on Principal in the amount
      of One Hundred Thousand ($100,000.00) Dollars from April 10, 2007 through the
      date that all of the Obligations are paid in full.




Counterparts .
      This
      Amendment No. 5 may be executed in one or more counterparts, including by
      facsimile, each of which shall be deemed an original, but all such counterparts
      together shall constitute but one and the same Amendment No. 5.




Governing
      Law .
      This
      Amendment No. 5 shall be governed by and construed in accordance with the
      internal laws (and not the law of conflicts) of such jurisdiction as shall
      be
      determined by Payee.




Except
      as
      set forth above, the Note, as amended pursuant to Amendment No. 1 Amendment
      No.
      2, Amendment No. 3 and Amendment No. 4, is not modified, changed or otherwise
      amended and remains in full force and effect in accordance with its terms as
      amended herein.




IN
      WITNESS WHEREOF, the undersigned have executed this Amendment No. 5 to the
      Note
      on April 10, 2007,


Protein
                Polymer Technologies, Inc., Maker,a
                Delaware corporationBy:
            /s/
              William N. Plamondon IIIWilliam
                N. Plamondon III,
              Chief
                Executive Officer


TAG
                Virgin Islands, Inc., as agent for
              Matthew
                J. Szulik, PayeeBy:
            /s/
              James TagliaferriJames
              Tagliaferri, President




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