UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    Form 10-Q

      (Mark One)

 x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
---                               ACT OF 1934

                For the quarterly period ended September 30, 1999

                                       OR

       TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
---                           EXCHANGE ACT OF 1934

        For the transition period from _____________ to ________________

                          Commission File No. 000-20139

                                  Diacrin, Inc.
             (Exact name of registrant as specified in its charter)


         Delaware                                         22-3016912
(State or other jurisdiction of                        (I.R.S. Employer
incorporation or organization)                         Identification No.)


                 Building 96 13th Street, Charlestown Navy Yard,
                   Charlestown, MA 02129 (Address of principal
                     executive offices, including zip code)

                                 (617) 242-9100
              (Registrant's telephone number, including area code)

         Indicate by check mark whether the registrant (1) has filed all reports
      required to be filed by Section 13 or 15(d) of the Securities Exchange Act
      of 1934 during the  preceding 12 months (or for such  shorter  period that
      the  registrant  was  required  to file  such  reports),  and (2) has been
      subject to such filing requirements for the past 90 days.

                           YES   X              NO
                              ------               ------

         Indicate  the  number of  shares  outstanding  of each of the  issuer's
      classes of common stock, as of the latest practicable date.

         As of October 31, 1999,  14,376,058  shares of the registrant's  Common
Stock were outstanding.


<PAGE>


                                  Diacrin, Inc.
                                      Index




                                                                 Page
PART I. - FINANCIAL INFORMATION

Item 1.   Financial Statements

           Balance Sheets as of
           December 31, 1998 and September 30, 1999............... 3

           Statements of Operations for each of the three and nine month
           periods ended September 30, 1998 and 1999.............. 4

           Statements of Cash Flows for each of the nine month periods
           ended September 30, 1998 and 1999...................... 5

           Notes to Financial Statements.......................... 6

Item 2.    Management's Discussion and Analysis of Financial
            Condition and Results of Operations................... 8

Item 3.    Quantitative and Qualitative Disclosure About
            Market Risk........................................... 12

PART II. -        OTHER INFORMATION

Item 2.           Changes in Securities and Use of Proceeds....... 13

SIGNATURES........................................................ 14

                                     - 2 -

<PAGE>


                                  Diacrin, Inc.
                                 Balance Sheets
                                   (Unaudited)
<TABLE>
<CAPTION>


                                                                        December 31,                September 30,
                                                                             1998                        1999
<S>                                                                <C>                        <C>
ASSETS
Current assets:
     Cash and cash equivalents                                        $    4,995,054             $     4,055,719
     Short-term investments                                               18,670,392                  13,470,574
     Interest receivable and other current assets                            394,413                     535,387
                                                                  ------------------          ------------------

         Total current assets                                             24,059,859                  18,061,680
                                                                    ----------------            ----------------

Property and equipment, at cost:
     Laboratory and manufacturing equipment                                  878,208                     891,753
     Equipment under capital lease                                           675,262                     675,262
     Furniture and office equipment                                          293,873                     302,078
     Leasehold improvements                                                   76,827                      77,529
                                                                 -------------------         -------------------
                                                                           1,924,170                   1,946,622
     Less- Accumulated depreciation and amortization                       1,199,673                   1,382,904
                                                                    ----------------           -----------------
                                                                             724,497                     563,718
                                                                   -----------------          ------------------

Long-term investments                                                      2,605,010                   4,743,445
Investment in joint venture                                                   94,508                     -
                                                                  ------------------           -----------------
                                                                           2,699,518                   4,743,445
                                                                    ----------------            ----------------

                                                                     $    27,483,874             $    23,368,843
                                                                     ===============             ===============
LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
     Accounts payable                                              $         268,002            $        121,694
     Accrued expenses                                                      1,359,982                   1,440,379
     Deferred revenue                                                        338,855                      -
     Current portion of long-term debt                                       280,724                     159,005
                                                                  ------------------          ------------------
         Total current liabilities                                         2,247,563                   1,721,078
                                                                   -----------------           -----------------

Long-term debt                                                               391,702                     281,667
                                                                   -----------------          ------------------

Stockholders' equity:
     Preferred stock, $.01 par value, authorized--
         5,000,000 shares; none issued and outstanding                        -                           -
     Common stock, $.01 par value; authorized-- 30,000,000
         shares; issued and outstanding--14,327,218 shares
         and 14,369,018 shares at December 31, 1998
         and September 30, 1999, respectively                                143,272                     143,690
     Additional paid-in capital                                           64,191,075                  64,234,279
     Accumulated deficit                                                 (39,489,738)                (43,011,871)
                                                                    ----------------            ----------------
              Total stockholders' equity                                  24,844,609                  21,366,098
                                                                    ----------------            ----------------

                                                                    $     27,483,874             $    23,368,843
                                                                    ================             ===============


                                              See Accompanying Notes to Financial Statements

                                     - 3 -

</TABLE>

<PAGE>


                                  Diacrin, Inc.
                            Statements of Operations
                                   (Unaudited)

<TABLE>
<CAPTION>

                                                            Three Months                        Nine Months
                                                        Ended September 30,                 Ended September 30,
                                                      1998              1999               1998             1999
                                                   ----------        ---------          --------         ---------
<S>                                           <C>                 <C>               <C>                <C>

REVENUES:
   Research and development                    $      790,867      $   712,185       $  2,840,585       $ 2,389,523
   Interest income                                    408,299          319,429          1,188,639         1,012,491
                                                   ----------       ----------          ---------         ---------
       Total revenues                               1,199,166        1,031,614          4,029,224         3,402,014
                                                   ----------       ----------          ---------         ---------

OPERATING EXPENSES:
    Research and development                        1,812,228        1,454,553          5,572,793         4,652,802
    General and administrative                        377,855          300,221          1,151,417           953,810
   Interest expense                                    20,951            8,977             71,208            36,931
                                                   ----------       ----------          ---------        ----------
       Total operating expenses                     2,211,034        1,763,751          6,795,418         5,643,543
                                                   ----------       ----------          ---------        ----------

EQUITY IN OPERATIONS
    OF JOINT VENTURE                                 (290,658)        (441,936)          (594,897)       (1,280,604)
                                                   ----------       ----------          ---------        ----------

NET LOSS                                         $ (1,302,526)   $  (1,174,073)      $ (3,361,091)     $ (3,522,133)
                                                 =============   ==============      =============     =============

NET LOSS PER COMMON SHARE                           $    (.09)      $    (.08)         $     (.24)     $      (.25)
                                                    ==========      ==========        ============     ============

SHARES USED IN COMPUTING
    NET LOSS PER COMMON SHARE                      14,322,066       14,367,608          14,099,970       14,359,082
                                                   ==========       ==========          ==========       ==========



















                 See Accompanying Notes to Financial Statements

                                     - 4 -

</TABLE>



<PAGE>


                                  Diacrin, Inc.
                            Statements of Cash Flows
                                   (Unaudited)
<TABLE>
<CAPTION>

                                                                                        Nine Months
                                                                                    Ended September 30,
                                                                                  1998              1999
<S>                                                                        <C>               <C>

CASH FLOWS FROM OPERATING ACTIVITIES:
    Net loss                                                                $ (3,361,091)     $ (3,522,133)
    Adjustments to reconcile net loss to net
       cash used in operating activities-
          Depreciation and amortization                                          261,830           183,231
          Equity in operations of joint venture                                  594,897         1,280,604
    Changes in assets and liabilities-
       Interest receivable and other current assets                              (97,926)         (140,974)
       Accounts payable                                                          (11,234)         (146,308)
       Accrued expenses                                                          119,033           (98,256)
       Deferred revenue                                                         (144,439)         (338,855)
                                                                             -----------       -----------

              Net cash used in operating activities                           (2,638,930)       (2,782,691)
                                                                             -----------       -----------
CASH FLOWS FROM INVESTING ACTIVITIES:
    (Increase) decrease in short-term investments                            (10,808,278)        5,199,818
    Purchases of property and equipment, net                                     (65,790)          (22,452)
    Decrease (increase) in long-term investments                               4,913,160        (2,138,435)
    Investment in joint venture                                               (1,204,572)       (1,803,950)
    Return of capital for services provided on behalf of joint venture           651,954           796,508
                                                                             -----------       -----------

              Net cash (used in) provided by investing activities             (6,513,526)        2,031,489
                                                                             -----------       -----------
CASH FLOWS FROM FINANCING ACTIVITIES:
    Net proceeds from sale of common stock                                     9,469,312            43,622
    Principal payments on long-term debt                                        (250,056)         (231,755)
                                                                             -----------       -----------

              Net cash provided by (used in) financing activities              9,219,256          (188,133)
                                                                             -----------       -----------
NET INCREASE (DECREASE) IN CASH
    AND CASH EQUIVALENTS                                                          66,800          (939,335)

CASH AND CASH EQUIVALENTS, beginning of period                                 5,015,777         4,995,054
                                                                             -----------       -----------

CASH AND CASH EQUIVALENTS, end of period                                   $   5,082,577     $   4,055,719
                                                                           =============     =============

SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
    Interest paid during the period                                        $      71,208    $       36,931
                                                                           =============    ==============



                 See Accompanying Notes to Financial Statements

                                     - 5 -

</TABLE>

<PAGE>



                                  Diacrin, Inc.
                          Notes to Financial Statements
                                   (Unaudited)

1.       Operations and Basis of Presentation

         Diacrin,  Inc. (the "Company") was incorporated on October 10, 1989 and
is developing transplantable cells for the treatment of human diseases which are
characterized by cell dysfunction or cell death and for which current  therapies
are either inadequate or nonexistent.

         The  financial  statements  included  herein have been  prepared by the
Company,  without audit, pursuant to the rules and regulations of the Securities
and  Exchange  Commission  and  include,  in  the  opinion  of  management,  all
adjustments,  consisting of normal, recurring adjustments,  necessary for a fair
presentation  of  interim  period  results.  Certain  information  and  footnote
disclosures  normally  included in financial  statements  prepared in accordance
with generally  accepted  accounting  principles  have been condensed or omitted
pursuant to such rules and regulations.  The Company believes, however, that its
disclosures are adequate to make the information  presented not misleading.  The
results for the interim  periods  presented  are not  necessarily  indicative of
results to be expected  for the full fiscal  year.  These  financial  statements
should be read in conjunction  with the audited  financial  statements and notes
thereto  included in the Company's  latest Annual Report on Form 10-K filed with
the Securities and Exchange Commission.

2.       Summary of Significant Accounting Policies

         (a)      Research and Development

         In  September  1996,  the Company and Genzyme  Corporation  ("Genzyme")
formed a joint  venture  (the  "Joint  Venture")  to develop  and  commercialize
NeuroCell(TM)-PD  for Parkinson's disease and  NeuroCell(TM)-HD for Huntington's
disease (the "Joint Venture  Products").  The Joint Venture is funded by Genzyme
and the Company in  accordance  with the terms of the joint  venture  agreement.
Collaborative  revenue  under  the  joint  venture  agreement  with  Genzyme  is
recognized as revenue to the extent that the Company's  research and development
costs are funded by Genzyme  through the Joint  Venture.  The  Company  receives
non-refundable  monthly  advances  from  the  Joint  Venture.  Deferred  revenue
represents  amounts  received  prior to  recognition  of revenue.  Research  and
development costs are expensed as incurred.

         (b)      Net Loss per Common Share

          In  accordance  with  Statement  of  Financial   Accounting  Standards
("SFAS") No. 128, Earnings per Share,  basic net loss per share is calculated by
dividing the net loss applicable to common  stockholders by the weighted average
number of common shares outstanding for all periods presented.  Diluted net loss
is the same as basic net loss because the  inclusion  of potential  common stock
from the  issuance  of stock  options  and  warrants  of 406,969  and 473,225 at
September 30, 1999 and 1998, respectively, would be antidilutive.


                                     - 6 -

<PAGE>


                                  Diacrin, Inc.
                          Notes to Financial Statements
                                   (Unaudited)

         (c)       New Accounting Standards

         In June 1998,  the FASB issued SFAS No. 133,  Accounting for Derivative
Instruments  and Hedging  Activities.  The  statement is effective  for the year
ended  December 31, 2000.  SFAS No. 133  establishes  accounting  and  reporting
standards for derivative  instruments  including certain derivative  instruments
embedded in other contracts  (collectively  referred to as derivatives)  and for
hedging  activities.  The Company does not expect  adoption of this statement to
have a material impact on the Company's financial statements.

3.       Cash Equivalents and Investments

         The  Company's  cash  equivalents  and  investments  are  classified as
held-to-maturity  and are carried at amortized cost, which  approximates  market
value. Cash equivalents,  short-term  investments and long-term investments have
maturities  of less than three  months,  less than one year and greater than one
year,  respectively.  Cash  equivalents  consisted  primarily  of a money market
mutual fund at December 31, 1998 and September 30, 1999. Short-term  investments
and long-term  investments consisted of corporate notes at December 31, 1998 and
September 30, 1999. At September 30, 1999, short-term  investments and long-term
investments  had a  remaining  average  maturity  of 4  months  and  13  months,
respectively.


                                     - 7 -

<PAGE>






Item 2.           Management's Discussion and Analysis of Financial Condition
                  and Results of Operations

Overview

                  Since its inception,  the Company has principally  focused its
efforts  and  resources  on research  and  development  of cell  transplantation
products to treat  neurodegenerative  and other human  diseases.  The  Company's
primary source of working capital to fund such activities has been proceeds from
the sale of equity and debt securities. In addition, commencing October 1, 1996,
the Company has received  funding from its Joint Venture with Genzyme in support
of the NeuroCell(TM)-PD and NeuroCell(TM)-HD  product development programs.  The
Company has not received any revenues from the sale of products to date and does
not expect to generate product revenues for at least the next several years. The
Company has  experienced  fluctuating  operating  losses since its inception and
expects that the additional activities required to develop and commercialize the
Company's  products will result in increasing  operating losses for at least the
next several  years.  At  September  30,  1999,  the Company had an  accumulated
deficit of $43.0 million.

                  In  September  1996,  the Company  and Genzyme  formed a Joint
Venture to develop and commercialize  NeuroCell(TM)-PD and NeuroCell(TM)-HD.  In
connection  with the  formation  of the Joint  Venture,  the Company  granted an
exclusive right and license to the patent rights and technology  relating to the
Joint  Venture  Products.  This  right  and  license  was  considered  to be the
Company's initial capital  contribution to the Joint Venture.  The Company has a
50% ownership  interest in the Joint  Venture.  Under the terms,  and subject to
certain conditions, of the joint venture agreement,  which was effective October
1 1996,  Genzyme has agreed to provide  100% of the first $10 million in funding
and  75% of the  following  $40  million  in  funding  for the  development  and
commercialization  of the Joint Venture Products.  The Company agreed to provide
the remaining 25% of the following $40 million in funding. All costs incurred in
excess of $50 million are to be shared equally  between  Genzyme and the Company
in  accordance  with the terms of the  agreement.  The Joint  Venture plans that
Diacrin  and  Genzyme  will  perform,  on  behalf  of  the  Joint  Venture,  the
development  activities in connection  with the Joint Venture  Products and that
Genzyme will market and sell the Joint Venture Products on a cost  reimbursement
basis on behalf of the Joint Venture.

                  For 1996 and 1997,  the  Company  expensed  all  research  and
development costs related to the Joint Venture Products incurred by it on behalf
of the Joint Venture and recognized an equal amount of research and  development
revenue due to the fact that costs  incurred  were  funded by the Joint  Venture
exclusively out of  contributions  made to it by Genzyme.  Through  December 31,
1997,  Genzyme made 100% of the total cash contributions to the Joint Venture on
a monthly  basis,  in  advance.  During  the first  quarter  of 1998,  the Joint
Venture's  cumulative  funding  requirements  since its  inception  exceeded $10
million. As such, the Company, as required by the joint venture agreement, began
making  cash  contributions  to the  Joint  Venture  equal  to 25% of the  Joint
Venture's monthly funding requirements. The Joint Venture's funding requirements
are  determined  on a monthly  basis by the  Company  and Genzyme and are met by
monthly  contributions from both parties in percentages  prescribed by the terms
of the joint venture  agreement.  To the extent the Company's  contributed funds
are used to fund  expenses  incurred by Genzyme on behalf of the Joint  Venture,
the Company  recognizes  an expense in its  statement  of  operations  captioned
"equity  in  operations  of  Joint  Venture."  Furthermore,  to the  extent  the
Company's contributed funds are used to fund expenses incurred by the Company on
behalf of the Joint Venture,  the Company  reduces the research and  development
revenue  recognized  by it from the  Joint  Venture  by an  amount  equal to the
Company-funded portion of such expenses.

                                     - 8 -

<PAGE>

         Any profits of the Joint  Venture  are to be shared  equally by Genzyme
and the  Company.  Losses of the Joint  Venture are  allocated  to each party in
proportion to the funding provided by each party.

Results of Operations

Three Months Ended September 30, 1999 Versus Three Months Ended
September 30, 1998

                  Research and development  revenues of  approximately  $712,000
for the three months ended  September 30, 1999 and $791,000 for the three months
ended September 30, 1998 were derived exclusively from the Joint Venture and was
relatively unchanged between periods.

         Interest  income was $319,000 and $408,000 for the three month  periods
ended September 30, 1999 and 1998, respectively.  This 22% decrease was due to a
decrease in the cash and investments on hand between the periods.

         Research  and  development  expenses  were $1.5  million  for the three
months ended  September  30, 1999 versus $1.8 million for the three months ended
September  30,  1998.  This 20%  decrease  was  primarily  due to a reduction in
preclinical  related research as most of the Company's  product  candidates have
begun clinical testing.

         General and administrative  expenses were $300,000 and $378,000 for the
three months ended September 30, 1999 and 1998, respectively.  This 21% decrease
was primarily due to decreased salary costs.

         For the three months  ended  September  30, 1999 and 1998,  the Company
recorded  an expense of  $442,000  and  $291,000,  respectively,  related to its
equity  in  operations  of the  joint  venture.  This  expense  was due to funds
contributed  by the Company to the Joint Venture that were used to fund expenses
incurred by Genzyme on behalf of the Joint Venture.

         The Company incurred a net loss of  approximately  $1.2 million for the
three months ended September 30, 1999 versus  approximately $1.3 million for the
three months ended September 30, 1998.

Nine Months Ended September 30, 1999 Versus Nine Months Ended September 30, 1998

                  Research and  development  revenues  were  approximately  $2.4
million for the nine months ended September 30, 1999 versus $2.8 million for the
nine months ended September 30, 1998 and were derived exclusively from the Joint
Venture.  This  reduction in research  and  development  revenues was  primarily
attributable  to the reduction from 100% to 75% in the percentage of funding for
the Joint Venture  provided by Genzyme which took effect in the first quarter of
1998.

         Interest  income was $1.0  million and $1.2  million for the nine month
periods ended September 30, 1999 and 1998,  respectively.  This 15% decrease was
due to a decrease in cash and investments on hand between the periods.

         Research and development expenses were $4.7 million for the nine months
ended September 30, 1999 versus $5.6 million for the nine months ended September
30,  1998.  This 17%  decrease  was  primarily  due to the  production  costs of
clinical grade antibody produced during the prior year period for use in certain
of the Joint Venture's planned clinical trials of NeuroCell(TM)-PD.

         General and administrative  expenses were $954,000 and $1.2 million for
the nine  months  ended  September  30,  1999 and 1998,  respectively.  This 17%
decrease was primarily due to decreased salary costs.

                                     - 9 -

<PAGE>

         For the nine months  ended  September  30,  1999 and 1998,  the Company
recorded an expense of $1.3 million and $595,000,  respectively,  related to its
equity  in  operations  of the  joint  venture.  This  expense  was due to funds
contributed  by the Company to the Joint Venture that were used to fund expenses
incurred by Genzyme on behalf of the Joint Venture. The Company was not required
to make  contributions to the Joint Venture prior to the quarter ended March 31,
1998. The increased  charge in the current year period was primarily a result of
the timing of the  commencement  of  contributions  by the  Company to the Joint
Venture in the prior year period.

         The Company incurred a net loss of  approximately  $3.5 million for the
nine months ended September 30, 1999 versus  approximately  $3.4 million for the
nine months ended September 30, 1998.

Liquidity and Capital Resources

         The Company has financed its activities primarily with the net proceeds
from equity offerings  aggregating $64 million and with interest earned thereon.
In addition,  the Company has recorded  approximately  $11.8  million in revenue
from the Joint  Venture  since it commenced on October 1, 1996. At September 30,
1999,  the Company had cash and cash  equivalents,  short-term  investments  and
long-term investments aggregating approximately $22.3 million.

         In November 1997, the Company borrowed  $650,000 at the Prime Rate plus
 .5% under an  unsecured  five-year  term loan with a bank to finance  production
equipment  acquired  during  1997.  As of  September  30,  1999 the  Company had
approximately $441,000 outstanding under the term loan with the bank and under a
master  lease  agreement  for  capital  equipment.  The  Company had no material
commitments for capital expenditures as of September 30, 1999.

         Under the joint venture agreement with Genzyme,  the Company's two lead
product development programs,  NeuroCell(TM)-PD for the treatment of Parkinson's
disease and  NeuroCell(TM)-HD  for the treatment of  Huntington's  disease,  are
being  developed by the Joint Venture.  Both Genzyme and Diacrin are responsible
for funding the Joint Venture in accordance  with the terms,  and subject to the
conditions,  of the joint venture agreement.  Genzyme agreed to fund 100% of the
first $10 million of  development  and  commercialization  costs  incurred after
October  1,  1996,  75%  of the  next  $40  million  and  50%  of all  remaining
development and commercialization  costs in excess of $50 million. After Genzyme
funds the first $10 million,  the Company is responsible  for funding 25% of the
next $40  million  and 50% of all  development  and  commercialization  costs in
excess of $50 million. As of September 30, 1999, approximately $20.7 million and
$3.6 million has been  contributed  to the Joint Venture by Genzyme and Diacrin,
respectively.  The  Company's  obligation  to  fund  25%  of the  program  costs
commenced  in the first  quarter of 1998.  The  Company  expects  that the Joint
Venture's 1999 product development plans, which are 25% funded by Diacrin,  will
significantly  increase the Company's net loss and cash and investments  used in
1999 as compared with 1998.

         The Company  believes that its existing  funds,  together with expected
future  funding  under  the  joint  venture  agreement  with  Genzyme,  will  be
sufficient to fund its operating expenses and capital  requirements as currently
planned through at least mid-2001.  However, the Company's cash requirements may
vary  materially  from those now  planned  because of  results of  research  and
development,  the scope and results of  preclinical  and clinical  testing,  any
termination of the Joint Venture, relationships with strategic partners, changes
in the focus and direction of the Company's  research and development  programs,
competitive and technological advances, the FDA's regulatory process, the market
acceptance  of any  approved  Company  products  and other  factors.  For a more
detailed  discussion  of these and other  factors that may affect the  Company's
future operating  results,  see the Company's Annual Report on Form 10-K for the
year  ended  December  31,  1998,  as filed  with the  Securities  and  Exchange
Commission.

                                     - 10 -

<PAGE>

         The Company expects to incur substantial  additional  costs,  including
costs  related to  ongoing  research  and  development  activities,  preclinical
studies,  clinical  trials,  establishing  pig production  capabilities  and the
expansion of its laboratory and administrative  activities.  Therefore, in order
to achieve  commercialization  of its potential products,  the Company will need
substantial additional funds. There can be no assurance that the Company will be
able to obtain the additional  funding that it will require on acceptable terms,
if at all.

Impact of the Year 2000 Issue

         The Company is in the process of completing its assessment of Year 2000
issues and their  potential  impact on its  information  systems  and  business.
Generally,  the  Company has  potential  Year 2000  exposure in four areas:  (i)
financial and management operating computer systems used to manage the Company's
business,  (ii) operating  computer  systems used in the Company's  research and
product  development  laboratories,  (iii)  microprocessors and other electronic
equipment used by the Company  ("embedded chips") and (iv) computer systems used
by third  parties,  in particular  financial  institutions  and suppliers of the
Company.

         At September 30, 1999,  the Company had completed its assessment of its
financial and management  operating  computer systems,  had identified  software
that is not Year 2000  compliant  and had  updated  this  software,  through the
purchase of an  off-the-shelf  software  package,  together  with  hardware  and
network server software. The Company spent approximately $5,000 in this effort.

         At September 30, 1999, the Company had also completed its assessment of
its Year 2000  exposure to  operating  computer  systems  used in the  Company's
research and development  laboratories  and embedded chips in its facilities and
equipment  used  in  its   facilities.   The  Company  has  not  identified  any
non-compliant  systems that play a significant  role in the Company's  research,
product development or facilities management.

         The Company continues to interview  financial  institutions and vendors
to determine  their exposure to year 2000 issues,  their  anticipated  risks and
responses to those  risks.  To date,  the Company has not  obtained  information
suggesting any critical  vendors or financial  institutions  will not be able to
service or supply the Company on or after January 1, 2000.

         The Company  does not  separately  track the  internal  costs  incurred
related to its year 2000  compliance  efforts  and,  therefore,  these costs are
unknown.  To date, costs incurred  principally relate to employee payroll costs.
Although  the  aggregate  additional  costs of the  Company's  year 2000 program
cannot be known at this time, it is not currently expected to be material.

         If  the  Company  is   unsuccessful   in  completing   remediation   of
non-compliant  systems,  or if any of the  Company's  third party  suppliers and
partners do not timely complete their remediation programs, additional costs may
be incurred to develop  alternative  methods of managing the effected aspects of
the Company's  business.  In addition,  the Company's  clinical and  preclinical
trials  for  all of its  product  candidates  could  be  delayed.  Based  on the
information  currently  available  to the  Company,  Year  2000  issues  are not
expected  to have a  significant  impact on the  Company's  ongoing  results  of
operations. Accordingly, the Company has not identified a most reasonably likely
worst case scenario and has not developed contingency plans.

                                     - 11 -

<PAGE>



Item 3.  Quantitative and Qualitative Disclosures About Market Risk

         The Company owns  financial  instruments  that are  sensitive to market
risks as part of its investment  portfolio.  The investment portfolio is used to
preserve  the  Company's  capital  until  it is  required  to  fund  operations,
including  the  Company's  research and  development  activities.  None of these
market-risk sensitive instruments are held for trading purposes.  The investment
portfolio  contains  instruments  that are  subject  to the risk of  decline  in
interest rates.

         Interest  Rate  Risk  - The  Company's  investment  portfolio  includes
investment  grade debt  instruments.  These bonds are  subject to interest  rate
risk, and could decline in value if interest rates fluctuation. Due to the short
duration  and  conservative  nature of these  instruments,  the Company does not
believe that it has a material exposure to interest rate risk.


                                     - 12 -

<PAGE>



                           PART II. OTHER INFORMATION

Item 2.  Changes in Securities and Use of Proceeds

         (c) The Company did not sell any equity  securities  during the quarter
ended June 30, 1999 that were not registered under the Securities Act.

         (d) The following  information  updates and supplements the information
regarding use of proceeds  originally filed by Diacrin on Form SR for the period
ended May 12,  1996,  as amended to date and relates to  securities  sold by the
Company pursuant to the  Registration  Statement on Form S-2  (Registration  No:
33-80773) which was declared  effective on February 12, 1996:  Through September
30,  1999,  the  Company  has used  approximately  $12,400,000  of the total net
proceeds from its initial public  offering of  $20,911,755.  Of the  $12,400,000
used,  approximately  $288,000  was  used  for the  purchase  of  machinery  and
equipment;  approximately  $814,000 was used for repayment of indebtedness;  and
approximately  $11,298,000 was used for working capital.  The unused proceeds of
approximately  $8,512,000 are in temporary  investments  consisting of corporate
notes and a money market mutual fund.  All proceeds used or invested were direct
or indirect payments to others.




                                     - 13 -

<PAGE>


                                   SIGNATURES

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                                     Diacrin, Inc.



November 12,  1999                                     /s/  Thomas H. Fraser
                                                     --------------------------
                                                            Thomas H. Fraser
                                                            President and Chief
                                                            Executive Officer



                                                       /s/  Kevin Kerrigan
                                                     --------------------------
                                                            Kevin Kerrigan
                                                            Controller


                                     - 14 -