**Exhibit      32.1**

**Certification**

**Pursuant      to Section 906 of the Sarbanes-Oxley Act of 2002**

**(Subsections      (a) and (b) of Section 1350, Chapter 63 of Title 18, United States      Code)**

|   | Date:  November                  9, 2007 |   | /s/                  Harvey J. Berger,                  M.D                                                                     |
|--------|----------------------------------------------------|--------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|   |                                               |   | Harvey                  J. Berger, M.D.Chairman                  and Chief Executive Officer                                                                                                                                                                                                                                                                                                   |
|   |                                               |   |                                                                                                                                                                                                                                                                                                                                                                                           |
|   |                                               |   |                                                                                                                                                                                                                                                                                                                                                                                           |
|   | Date:  November                  9, 2007 |   | /s/                  Edward M.                  Fitzgerald                                                       |
|   |                                               |   | Edward                  M. Fitzgerald                                                                                                                                                                                                                                                                                                                                                          |
|   |                                               |   | Senior                  Vice President,Finance                  and Corporate Operations, andChief                  Financial                  Officer                                                                                                                                                                                                                                         |