36492 Federal Register / Vol. 74, No. 140 / Thursday, July 23, 2009 / Notices 

social networking sites (without 

parental consent) for surveys. The 

Academy for Educational Development 

will be conducting the research. There 

is no cost to respondents other than 

their time. The total estimated annual 

burden hours are 481. 

ESTIMATED ANNUALIZED BURDEN HOURS

Type of respondent Form name Number of 

respondents 

Number 

of responses 

per 

respondent 

Average 

burden per 

response 

(in hours) 

Parents of 15–17 yr old .................................. Focus Group Screener for Parents of Minors 54 1 5/60 

Females (15–17 yr old) ................................... Focus Group Screener for Minors ................. 54 1 5/60 

Female (18–25 yr old) .................................... Focus Group Screener for Adult Women ...... 126 1 5/60 

Female (15–25 yr old) .................................... Focus Group Moderator Guide (15–25) ........ 180 1 2 

Female (15–25 yr old) .................................... Mall Intercept Screener & Moderator Guide 

(15–25).

200 1 10/60 

Female (15–25 yr old) .................................... Online Screener and Survey (15–25) ............ 500 1 8/60 

Dated: July 16, 2009. 

Marilyn S. Radke, 

Reports Clearance Officer, Centers for Disease 

Control and Prevention. 

[FR Doc. E9–17525 Filed 7–22–09; 8:45 am] 

BILLING CODE 4163–18–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Agency for Toxic Substances and 

Disease Registry 

[ATSDR–253] 

Availability of Draft Toxicological 

Profile for Perfluoroalkyls 

AGENCY: Agency for Toxic Substances 

and Disease Registry (ATSDR), 

Department of Health and Human 

Services (HHS). 

ACTION: Notice of availability. 

SUMMARY: This notice announces the 

availability of the draft toxicological 

profile for perfluoroalkyls, prepared by 

ATSDR, for review and comment. 

DATES: In order to be considered, 

comments on this draft toxicological 

profile must be received on or before 

October 30, 2009. Comments received 

after the public comment period will be 

considered at the discretion of ATSDR 

on the basis of what is deemed to be in 

the best interest of the general public. 

ADDRESSES: Requests for a printed copy 

of the draft toxicological profile should 

be sent to the attention of Ms. Olga 

Dawkins, Division of Toxicology and 

Environmental Medicine, Agency for 

Toxic Substances and Disease Registry, 

Mailstop F–32, 1600 Clifton Road, NE., 

Atlanta, Georgia 30333. Electronic 

access to the document is also available 

at the ATSDR Web site: http:// 

www.atsdr.cdc.gov/toxpro2.html. 

Requests for printed copies of the 

draft toxicological profile must be in 

writing and must specifically identify 

the toxicological profile that you wish to 

receive. ATSDR reserves the right to 

provide free of charge only one copy of 

each profile requested. In case of 

extended distribution delays, requestors 

will be notified. 

Comments regarding the draft 

toxicological profile for perfluoroalkyls 

should be sent to the attention of Ms. 

Nickolette Roney, Division of 

Toxicology and Environmental 

Medicine, Agency for Toxic Substances 

and Disease Registry, Mailstop F–62, 

1600 Clifton Road, NE., Atlanta, Georgia 

30333. Electronic comments may be 

sent to TPPublicComments@cdc.gov. All 

comments sent electronically should 

contain the docket control number 

ATSDR–253 in the subject line. 

Written comments and other data 

submitted in response to this notice and 

the draft toxicological profile should 

bear the docket control number ATSDR– 

253. Send one copy of all comments and 

three copies of all supporting 

documents to Ms. Roney at the above 

address by the end of the comment 

period. Because all public comments 

regarding ATSDR toxicological profiles 

are available for public inspection, no 

confidential information should be 

submitted in response to this notice. 

FOR FURTHER INFORMATION CONTACT: Ms. 

Olga Dawkins, Division of Toxicology 

and Environmental Medicine, Agency 

for Toxic Substances and Disease 

Registry, Mailstop F–62, 1600 Clifton 

Road, NE., Atlanta, Georgia 30333; 

telephone number (800) 232–4636 or 

(770) 488–3315. 

SUPPLEMENTARY INFORMATION: This draft 

toxicological profile for perfluoroalkyls 

was prepared in accordance with 

guidelines developed by the Agency for 

Toxic Substances and Disease Registry 

and the Environmental Protection 

Agency (EPA) for the preparation of 

toxicological profiles. The original 

guidelines were published in the 

Federal Register on April 17, 1987. 

While perfluoroalkyls are not found on 

the ATSDR Priority List of Hazardous 

Substances, ATSDR has determined that 

a profile for these substances was 

necessary because data indicate that 

some perfluoroalkyls are found in the 

blood of the United States general 

population and in the environment. The 

agency also determined that it was 

important to characterize the current 

available information regarding the 

health effects from exposure to 

perfluoroalkyls in order to support and 

inform public health responses and 

activities by ATSDR and others. This 

profile will be revised and republished 

as necessary. 

Section 104(i)(3) of the 

Comprehensive Environmental 

Response, Compensation, and Liability 

Act [42 U.S.C. 9604(i)(3)] outlines the 

content of the toxicological profiles. 

Each profile includes an examination, a 

summary, and an interpretation of 

available toxicological information and 

epidemiologic evaluations. This 

information and these data are to be 

used to identify the levels of significant 

human exposure to a substance and the 

associated health effects. The profiles 

must also include a determination of 

whether adequate information on the 

health effects of each substance is 

available or in the process of 

development. When adequate 

information is not available, ATSDR, in 

cooperation with the National 

Toxicology Program (NTP), will initiate 

a research program to determine these 

health effects. 

Although key studies for this 

substance were considered during the 

profile development process, this 

Federal Register notice solicits any 

additional studies, particularly 

unpublished data and ongoing studies, 

which will be evaluated for possible 

addition to the profile now or in the 

future. 


erowe on DSK5CLS3C1PROD with NOTICES
Federal Register / Vol. 74, No. 140 / Thursday, July 23, 2009 / Notices 36493 

The following draft toxicological 

profile will be made available to the 

public on or about July 6, 2009. 

Document Toxicological profile CAS No. 

1 ................................................................. PERFLUOROALKYLS .................................................................................................. 000375–22–4 

000335–67–1 

001763–23–1 

All profiles issued as ‘‘Draft for Public 

Comment’’ represent ATSDR’s best 

efforts to provide important 

toxicological information on priority 

substances. We are seeking public 

comments and additional information 

that may be used to supplement this 

profile. ATSDR remains committed to 

providing a public comment period for 

these documents as the best means to 

serve public health and our clients. 

Ken Rose, 

Director, Office of Policy, Planning, and 

Evaluation, National Center for 

Environmental Health/Agency for Toxic 

Substances and Disease Registry. 

[FR Doc. E9–17529 Filed 7–22–09; 8:45 am] 

BILLING CODE 4163–70–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Agency for Toxic Substances and 

Disease Registry 

[ATSDR–254] 

Notice of Development of Set 23 

Toxicological Profiles 

AGENCY: Agency for Toxic Substances 

and Disease Registry (ATSDR), 

Department of Health and Human 

Services (HHS). 

ACTION: Notice. 

SUMMARY: This notice announces the 

development of Set 23 Toxicological 

Profiles. Set 23 Toxicological Profiles 

consists of three new drafts and two 

updated drafts. These profiles will be 

available to the public on or about 

October 17, 2009. Electronic access to 

these documents will be available at the 

ATSDR Web site: http:// 

www.atsdr.cdc.gov/toxpro2.html. 

Set 23 Toxicological Profiles 

The following toxicological profiles 

are now being developed: 

Toxicological profile CAS No. 

1. Acrylamide* ...................................................................................................................................... 79–06–1 

2. Carbon Monoxide* ........................................................................................................................... 630–08–0 

3. 1,3-Butadiene .................................................................................................................................. 106–99–0 

4. Phosphate Ester Flame Retardants* ............................................................................................... 126–73–8, 126–71–6, 78–51–3, 115–86–6, 

13674–84–5, 13674–87–8, 115–96–8 

5. Vanadium ......................................................................................................................................... 7440–62–2 

* Denotes new profile. 

SUPPLEMENTARY INFORMATION: The 

Superfund Amendments and 

Reauthorization Act of 1986 (SARA) (42 

U.S.C. 9601 et seq.) amended the 

Comprehensive Environmental 

Response, Compensation, and Liability 

Act of 1980 (CERCLA or Superfund) (42 

U.S.C. 9601 et seq.) by establishing 

certain requirements for ATSDR and the 

U.S. Environmental Protection Agency 

(EPA) with regard to hazardous 

substances that are most commonly 

found at facilities on the CERCLA 

National Priorities List (NPL). Among 

these statutory requirements is a 

mandate for the Administrator of 

ATSDR to prepare toxicological profiles 

for each substance included on the 

Priority List of Hazardous Substances 

(http://www.atsdr.cdc.gov/cercla/ 

07list.html). This list names 275 

hazardous substances that pose the most 

significant potential threat to human 

health as determined by ATSDR and 

EPA. The availability of the revised list 

of the 275 priority substances was 

announced in the Federal Register on 

March 6, 2008 (73 FR 12178). For prior 

versions of the list of substances, see 

Federal Register notices dated April 17, 

1987 (52 FR 12866); October 20, 1988 

(53 FR 41280); October 26, 1989 (54 FR 

43619); October 17, 1990 (55 FR 42067); 

October 17, 1991 (56 FR 52166); October 

28, 1992 (57 FR 48801); February 28, 

1994 (59 FR 9486); April 29, 1996 (61 

FR 18744; November 17, 1997 (62 FR 

61332); October 21, 1999 (64 FR 56792); 

October 25, 2001 (66 FR 54014); 

November 7, 2003 (68 FR 63098); and 

December 7, 2005 (70 FR 70284). 

The Set 23 Toxicological Profiles for 

1,3-Butadiene and Vanadium are 

updates of previously published profiles 

for NPL priority substances. In addition, 

to address emerging public health 

concerns related to substances not 

currently on the NPL, ATSDR is also 

developing Set 23 Toxicological Profiles 

for Carbon Monoxide, Acrylamide, and 

Phosphate Ester Flame Retardants. 

Carbon monoxide is a toxic gas 

produced from the incomplete 

combustion of carbon-based fuels. 

Because it is colorless and odorless, 

toxicity can occur with no indication 

that exposure is occurring. Thousands 

of hospitalizations and hundreds of 

deaths occur every year as a result of 

inadvertent exposure to carbon 

monoxide. Acrylamide is a known 

animal carcinogen that is widely used in 

industry to synthesize polyacrylamides. 

Acrylamide also occurs naturally in a 

few foods, is formed in many foods as 

a byproduct of numerous cooking 

processes, and has been detected 

recently in human biomonitoring 

studies. Phosphate ester flame 

retardants comprise a large group of 

structurally related chemicals with 

increasing uses in clothing, fabrics, 

furniture, and structural components. 

However, there is an increasing body of 

information regarding exposures, body 

burdens, and toxicity related to this 

group of chemicals. 


erowe on DSK5CLS3C1PROD with NOTICES