Exhibit 10.33

CONOR MEDSYSTEMS, INC,

EMPLOYMENT,
CONFIDENTIAL INFORMATION,

AND INVENTION ASSIGNMENT
AGREEMENT

As a condition of my employment with Conor Medsystems, Inc., its subsidiaries, affiliates, successors or
assigns (together the Company), and in consideration of my employment with the Company and my receipt of the compensation now and hereafter paid to me by Company, I agree to the following:

1. AT-WILL EMPLOYMENT. I understand and acknowledge that my
employment with the company is for an unspecified duration and constitutes at-will employment. I also understand that any representation to the contrary is unauthorized and not valid unless obtained in writing and signed by the president
of the company. I acknowledge that this employment relationship may be terminated at any time, with or without good cause or for any or no cause, at the option either of the company or myself, with or without notice.

2. CONFIDENTIAL INFORMATION.

(a) Company Information. I agree at all times during the term of my employment and thereafter, to hold in strictest confidence, and not to
use, except for the benefit of the Company, or to disclose to any person, firm or corporation without written authorization of the Board of Directors of the Company, any Confidential Information of the Company, except under a non-disclosure
agreement duly authorized and executed by the Company. I understand that Confidential Information means any nonpublic information that relates to the actual or anticipated business or research and development of the Company, technical
data, trade secrets or know-how, including, but not limited to, research, product plans or other information regarding Companys products or services and markets therefore, customer lists and customers (including, but not limited to, customers
of the Company on whom I called or with whom I became acquainted during the term of my employment), software, developments, inventions, processes, formulas, technology, designs, drawings, engineering, hardware configuration information, marketing,
finances or other business information. I further understand that Confidential Information does not include any of the foregoing items which have become publicly known and made generally available through no wrongful act of mine or of others who
were under confidentiality obligations as to the item or items involved or improvements or new versions thereof.

(b) Former Employer
Information. I agree that I will not, during my employment with the Company, improperly use or disclose any proprietary information or trade secrets of any former or concurrent employer or other person or entity and that I will not bring
onto the premises of the Company any unpublished document or proprietary information belonging to any such employer, person or entity unless consented to in writing by such employer, person or entity.

(c) Third Party Information. I recognize that the Company has received and in the future will receive from third parties their confidential
or proprietary information subject to a duty on the Companys part to maintain the confidentiality of such information and



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to use it only for certain limited purposes. I agree to hold all such confidential or proprietary information in the
strictest confidence and not to disclose it to any person, firm or corporation or to use it except as necessary in carrying out my work for the Company consistent with the Companys agreement with such third party.

3. INVENTIONS.

(a) Inventions Retained and Licensed. I have attached hereto, as Exhibit A, a list describing all inventions, original works of authorship, developments, improvements, and trade secrets which were
made by me prior to my employment with the Company (collectively referred to as Prior Inventions), which belong to me, which relate to the Companys proposed business, products or research and development, and which are not assigned
to the Company hereunder; or, if no such list is attached, I represent that there are no such Prior Inventions. If in the course of my employment with the Company, I incorporate into a Company product, process or service a Prior Invention owned by
me or in which I have an interest, I hereby grant to the Company a nonexclusive, royalty-free, fully paid-up, irrevocable, perpetual, worldwide license to make, have made, modify, use and sell such Prior Invention as part of or in connection with
such product, process or service, and to practice any method related thereto.

(b) Assignment of Inventions. I agree that I
will promptly make full written disclosure to the Company, will hold in trust for the sole right and benefit of the Company, and hereby assign to the Company, or its designee, all my right, title, and interest in and to any and all inventions,
original works of authorship, developments, concepts, improvements, designs, discoveries, ideas, trademarks or trade secrets, whether or not patentable or registrable under copyright or similar laws, which I may solely or jointly conceive or develop
or reduce to practice, or cause to be conceived or developed or reduced to practice, during the period of time I am in the employ of the Company (collectively referred to as Inventions), except as provided in Section 3(f) below. I
further acknowledge that all original works of authorship which are made by me (solely or jointly with others) within the scope of and during the period of my employment with the Company and which are protectible by copyright are works made
for hire, as that term is defined in the United States Copyright Act. I understand and agree that the decision whether or not to commercialize or market any invention developed by me solely or jointly with others is within the Companys
sole discretion and for the Companys sole benefit and that no royalty will be due to me as a result of the Companys efforts to commercialize or market any such invention. Notwithstanding anything contained herein, I shall not be required
to assign to the Company any rights I may have in inventions developed during the course of my engagement unless such inventions pertain to the research, development, design, manufacture or marketing of stents and vascular drug delivery systems.

(c) Inventions Assigned to the United States. I agree to assign to the United States government all my right, title, and
interest in and to any and all Inventions whenever such full title is required to be in the United States by a contract between the Company and the United States or any of its agencies.

(d) Maintenance of Records. I agree to keep and maintain adequate and current written records of all Inventions pertaining to the research,
development, design, manufacture or marketing of stents and vascular drug delivery systems made by me (solely or



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jointly with others) during the term of my employment with the Company. The records will be in the form of notes,
sketches, drawings, and any other format that may be specified by the Company. The records will be available to and remain the sole property of the Company at all times. Inventions notebooks, notes, designs, sketches, drawings and other records that
were originated before the incorporation of the Company will remain the sole property of John F. Shanley at all times, provided, however that the company will be entitled to copies of such records to the extent that they contain information relative
to the intellectual property that I have otherwise assigned to the Company.

(e) Patent and Copyright Registrations. I agree
to assist the Company, or its designee, at the Companys expense, in every proper way to secure the Companys rights in the Inventions and any copyrights, patents, mask work rights or other intellectual property rights relating thereto in
any and all countries, including the disclosure to the Company of all pertinent information and data with respect thereto, the execution of all applications, specifications, oaths, assignments and all other instruments which the Company shall deem
necessary in order to apply for and obtain such rights and in order to assign and convey to the Company, its successors, assigns, and nominees the sole and exclusive rights, title and interest in and to such Inventions, and any copyrights, patents,
mask work rights or other intellectual property rights relating thereto. I further agree that my obligation to execute or cause to be executed, when it is in my power to do so, any such instrument or papers shall continue after the termination of
this Agreement. If the Company is unable because of my mental or physical incapacity or for any other reason to secure my signature to apply for or to pursue any application for any United States or foreign patents or copyright registrations
covering Inventions or original works of authorship assigned to the Company as above, then I hereby irrevocably designate and appoint the Company and its duly authorized officers and agents as my agent and attorney in fact, to act for and in my
behalf and stead to execute and file any such applications and to do all other lawfully permitted acts to further the prosecution and issuance of letters patent or copyright registrations thereon with the same legal force and effect as if executed
by me.

(f) Exception to Assignments. I understand that the provisions of this Agreement requiring assignment of Inventions
to the Company do not apply to any invention which qualifies fully under the provisions of California Labor Code Section 2870 (attached hereto as Exhibit B).

4. CONFLICTING EMPLOYMENT. I agree that, during the term of my employment with the Company, I will not engage in any other employment,
occupation or consulting directly related to the business in which the Company is now involved or becomes involved during the term of my employment, nor will I engage in any other activities that conflict with my obligations to the Company.

5. RETURNING COMPANY DOCUMENTS. The Company
agrees that, at the time of leaving the employ of the Company, I will be permitted to keep in my possession file copies of certain documents including all personal correspondence, email records, personnel records pertaining to John F. or Nancy A.
Shanley, and copies of new invention notebooks, including, without limitation, those records maintained pursuant to paragraph 3(d). I agree to hold all such records in confidence pursuant to the confidentiality provisions of this agreement. I
further agree to deliver to the Company (and will not deliver to anyone else) originals or reproductions of any



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and all devices, records, data, notes, reports, proposals, lists, correspondence, specifications, drawings, blueprints,
sketches, materials, equipment, other documents or property developed by me pursuant to my employment with the Company or otherwise belonging to the Company, its successors or assigns, including, without limitation, those records maintained pursuant
to paragraph 3(d).

6. NOTIFICATION OF NEW
EMPLOYER. In the event that I leave the employ of the Company, I hereby grant consent to notification by the Company to my new employer about my rights and obligations under this Agreement.

7. SOLICITATION OF EMPLOYEES. l agree that for a
period of twelve (12) months immediately following the termination of my relationship with the Company for any reason, whether with or without cause, I shall not either directly or indirectly solicit, induce, recruit or encourage any of the
Companys employees to leave their employment, or take away such employees, or attempt to solicit, induce, recruit, encourage or take away employees of the Company, either for myself or for any other person or entity.

8. CONFLICT OF INTEREST GUIDELINES. I agree to
diligently adhere to the Conflict of Interest Guidelines attached as Exhibit D hereto.

9.
REPRESENTATIONS. I agree to execute any proper oath or verify any proper document required to carry out the terms of this Agreement. I represent that my performance of all the terms of this
Agreement will not breach any agreement to keep in confidence proprietary information acquired by me in confidence or in trust prior to my employment by the Company. I hereby represent and warrant that have not entered into, and I will not enter
into, any oral or written agreement in conflict herewith.

10. GENERAL
PROVISIONS.

(a) Governing Law; Consent to Personal Jurisdiction. This
Agreement will be governed by the laws of the State of California. I hereby expressly consent to the personal jurisdiction of the state and federal courts located in California for any lawsuit filed there against me by the Company arising from or
relating to this Agreement.

(b) Entire Agreement. This Agreement sets forth the entire agreement and understanding between
the Company and me relating to the subject matter contained herein and supersedes all prior discussions or representations between us including, but not limited to, any representations made during my interview(s) or relocation negotiations, whether
written or oral. No modification of or amendment to this Agreement, nor any waiver of any rights under this Agreement, will be effective unless in writing signed by the President of the Company and me. Any subsequent change or changes in my duties,
salary or compensation will not affect the validity or scope of this Agreement.

(c) Severability. If one or more of the
provisions in this Agreement are deemed void by law, then the remaining provisions will continue in full force and effect.



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(d) Successors and Assigns. This Agreement will be binding upon my heirs, executors,
administrators and other legal representatives and will be for the benefit of the Company, its successors, and its assigns.

Date:



/s/ John F. ShanleySignatureJohn F. ShanleyName of Employee (typed or printed)




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EXHIBIT A

LIST OF PRIOR INVENTIONS

AND ORIGINAL WORKS OF AUTHORSHIP



|      |  |      |  |                                        
|----- |  | ---- |  | ---------------------------------------
|Title |  | Date |  | Identifying Number or Brief Description

No
inventions or improvements

Additional
Sheets Attached

Signature of Employee:

Print Name of
Employee:

Date:



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EXHIBIT B

CALIFORNIA LABOR CODE SECTION 2870

INVENTION ON OWN TIME-EXEMPTION FROM
AGREEMENT

(a) Any provision in an employment agreement which provides that an employee shall assign, or offer to assign, any of his or her
rights in an invention to his or her employer shall not apply to an invention that the employee developed entirely on his or her own time without using the employers equipment, supplies, facilities, or trade secret information except for those
inventions that either:



| | (1) | Relate at the time of conception or reduction to practice of the invention to the employers business, or actual or demonstrably anticipated research or development of the
employer; or
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| | (2) | Result from any work performed by the employee for the employer.
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(b) To
the extent a provision in an employment agreement purports to require an employee to assign an invention otherwise excluded from being required to be assigned under subdivision (a), the provision is against the public policy of this state and is
unenforceable.



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EXHIBIT D

CONOR MEDSYSTEMS, INC.

CONFLICT OF INTEREST GUIDELINES

It is the policy of Conor Medsystems, Inc. to conduct its affairs in strict compliance with the letter and spirit of the law and to adhere to the highest
principles of business ethics. Accordingly, all officers, employees and independent contractors must avoid activities which are in conflict, or give the appearance of being in conflict, with these principles and with the interests of the Company.
The following are potentially compromising situations which must be avoided. Any exceptions must be reported to the President and written approval for continuation must be obtained.



| | 1. | Revealing confidential information to outsiders or misusing confidential information. Unauthorized divulging of information is a violation of this policy whether or not for personal
gain and whether or not harm to the Company is intended. (The Employment, Confidential Information, Invention Assignment and Arbitration Agreement elaborates on this-principle and is a binding agreement.)
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| | 2. | Accepting or offering substantial gifts, excessive entertainment, favors or payments which may be deemed to constitute undue influence or otherwise be improper or embarrassing to
the Company.
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| | 3. | Participating in civic or professional organizations that might involve divulging confidential information of the Company.
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| | 4. | Initiating or approving any form of personal or social harassment of employees.
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| | 5. | Investing or holding outside directorship in suppliers, customers, or competing companies, including financial speculations, where such investment or directorship might influence in
any manner a decision or course of action of the Company.
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| | 6. | Borrowing from or lending to employees, customers or suppliers.
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| | 7. | Acquiring real estate of interest to the Company.
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| | 8. | Improperly using or disclosing to the Company any proprietary information or trade secrets of any former or concurrent employer or other person or entity with whom obligations of
confidentiality exist.
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| | 9. | Unlawfully discussing prices, costs, customers, sales or markets with competing companies or their employees.
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| | 10. | Making any unlawful agreement with distributors with respect to prices.
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| | 11. | Improperly using or authorizing the use of any inventions which are the subject of patent claims of any other person or entity.
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| | 12. | Engaging in any conduct which is not in the best interest of the Company.
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Each officer, employee and independent contractor must take every necessary action to ensure compliance with these guidelines and to bring problem areas to the attention of higher management for review. Violations of
this conflict of interest policy may result in discharge without warning.



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