Exhibit 4.2


 





 


THIS WARRANT AND THE
UNDERLYING SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE “ACT”) AND MAY NOT BE OFFERED,
SOLD OR OTHERWISE TRANSFERRED, ASSIGNED, PLEDGED OR HYPOTHECATED UNLESS AND UNTIL REGISTERED UNDER THE ACT OR UNLESS THE COMPANY
HAS RECEIVED AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY AND ITS COUNSEL THAT SUCH REGISTRATION IS NOT REQUIRED.


 


CHIMERIX,
INC.


 


WARRANT TO PURCHASE STOCK


 


	No. PFW-[___]	February 7, 2011


 


This
Certifies That, for value received, [_____________] (the
“Holder”), is entitled to subscribe for and purchase at the Warrant Price (defined below) from Chimerix,
Inc., a Delaware corporation (the “Company”), all or any portion of the Shares (as defined below) during
the Exercise Period (as defined below).


 


This Warrant is issued
as one of a series of warrants (the “Series F Warrants”) pursuant to the Series F Preferred Stock and
Warrant Purchase Agreement dated as of the date hereof among the Company and the Investors listed on Schedule A thereto (the “Purchase
Agreement”). Capitalized terms used and not otherwise defined herein shall have the meanings given them in the Purchase
Agreement.


 


1.           Exercise
of Warrant. The terms and conditions upon which this Warrant may be exercised, and the Shares covered hereby may be
purchased, are as follows:


 


(a)          Term.
Subject to the terms and conditions hereof, this Warrant may be exercised at any time, or from time to time, in whole or in part,
on or after the date hereof; provided, however, that in no event may this Warrant be exercised after February 7, 2018 (the
“Exercise Period”).


 


(b)          Shares.
For purposes of this Warrant, the “Shares” shall mean [_________] fully paid and nonassessable shares
of the Series F Preferred Stock of the Company (“Series F Preferred”) (or such other number, class and
kind of shares as may be issuable hereunder pursuant to Section 4 below).


 


(c)          Warrant
Price. For purposes of this Warrant, the “Warrant Price” shall mean $2.045 per Share, subject
to adjustment pursuant to Section 4 below.


 




    	 



    	 



    

 


2.           Method
of Exercise. 


 


(a)          The
rights represented by this Warrant may be exercised in whole or in part at any time during the Exercise Period, by delivery of
the following to the Company at its address set forth in the Purchase Agreement (or at such other address as it may designate by
notice in writing to the Holder):


 


(i)          An
executed Notice of Exercise in the form attached hereto as Exhibit A;


 


(ii)         Payment
of the Warrant Price either (i) in cash or by check or (ii) by cancellation of indebtedness or (iii) by any combination thereof;
and


 


(iii)       This
Warrant.


 


Upon the exercise of
the rights represented by this Warrant, a certificate or certificates for the Shares so purchased, registered in the name of the
Holder or persons affiliated with the Holder, if the Holder so designates, shall be issued and delivered to the Holder promptly
after the rights represented by this Warrant shall have been so exercised.


 


The person in whose
name any certificate or certificates for Shares are to be issued upon exercise of this Warrant shall be deemed to have become the
holder of record of such Shares on the date on which this Warrant was surrendered and payment of the Warrant Price was made, irrespective
of the date of delivery of such certificate or certificates, except that, if the date of such surrender and payment is a date when
the stock transfer books of the Company are closed, such person shall be deemed to have become the holder of such Shares at the
close of business on the next succeeding date on which the stock transfer books are open.


 


(b)         Net
Exercise. Notwithstanding any provisions herein to the contrary, if the Fair Market Value (as defined below) of one Share is
greater than the Warrant Price (at the date of calculation as set forth below), in lieu of exercising this Warrant by payment of
cash, the Holder may elect to receive Shares equal to the value (as determined below) of this Warrant (or the portion thereof being
canceled) by surrender of this Warrant at the principal office of the Company together with the properly endorsed Notice of Exercise,
in which event the Company shall issue to the Holder a number of Shares computed using the following formula:


X = Y (A-B)


    A


 


	Where:	X =	the number of Shares to be issued to the Holder
	 	 	 
	 	Y =	the number of Shares purchasable under the Warrant or, if only a portion of the Warrant is being exercised, the portion of the Warrant being exercised (at the date of such calculation)
	 	 	 
	 	A =	the Fair Market Value of one Share (at the date of such calculation)
	 	 	 
	 	B =	the Warrant Price (as adjusted to the date of such calculation)


 




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For purposes of this
Warrant, the fair market value of one Share (the “Fair Market Value”) shall mean, with respect to each
such Share, the value as determined by the Company’s Board of Directors in good faith; provided, however, that in
the event that this Warrant is exercised pursuant to this Section 2(b) in connection with the Company’s initial public
offering of its Common Stock, the Fair Market Value of one Share shall be the product of (i) the per share offering price to the
public of the Company’s initial public offering, and (ii) the number of shares of Common Stock into which each Share is convertible
at the time of such exercise.


 


3.           Covenants
of the Company. The Company covenants and agrees that all Shares that may be issued upon the exercise of the rights
represented by this Warrant will, upon issuance, be validly issued and outstanding, fully paid and nonassessable, and free from
all taxes, liens and charges with respect to the issuance thereof (other than taxes, liens or charges created by or imposed upon
the Holder through no action of the Company). The Company further covenants and agrees that the Company will at all times during
the Exercise Period have authorized and reserved a sufficient number of shares of Preferred Stock to provide for the exercise of
the rights represented by this Warrant. If at any time during the Exercise Period the number of authorized but unissued shares
of Preferred Stock shall not be sufficient to permit exercise of this Warrant, the Company will take such corporate action as may,
in the opinion of its counsel, be necessary to increase its authorized but unissued shares of Preferred Stock to such number of
shares as shall be sufficient for such purposes.


 


4.           Adjustment.
In the event of changes in the outstanding shares of the Series F Preferred by reason of stock dividends, split-ups, recapitalizations,
reclassifications, conversions, mergers, combinations or exchanges of shares, separations, reorganizations, liquidations, or the
like, the number and class of shares available under this Warrant in the aggregate and the Warrant Price and Shares shall be correspondingly
adjusted to give the Holder of the Warrant, on exercise for the same aggregate Warrant Price, the total number, class, and kind
of shares as the Holder would have owned had the Warrant been exercised prior to the event and had the Holder continued to hold
such shares until after the event requiring adjustment.


 


5.           Adjustment
Certificate. When any adjustment is required to be made in the Shares or the Warrant Price pursuant to Section 4 or
otherwise, the Company shall promptly mail to the Holder a certificate setting forth (i) a brief statement of the facts requiring
such adjustment, (ii) the Warrant Price after such adjustment and (iii) the kind and amount of stock or other securities or property
into which this Warrant shall be exercisable after such adjustment.


 


6.           Fractional
Shares. No fractional shares shall be issued upon the exercise of this Warrant as a consequence of any adjustment pursuant
hereto. All Shares (including fractions) issuable upon exercise of this Warrant may be aggregated for purposes of determining whether
the exercise would result in the issuance of any fractional share. If, after aggregation, the exercise would result in the issuance
of a fractional share, the Company shall, in lieu of issuance of any fractional share, pay the Holder otherwise entitled to such
fraction a sum in cash equal to the product resulting from multiplying the then current Fair Market Value of a Share by such fraction.


 




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7.          Early
Termination. Notwithstanding Section 1(a), in the event of an Acquisition or Asset Transfer (each as defined in the
Company’s Amended and Restated Certificate of Incorporation) at any time during the Exercise Period, the Company shall provide
to the Holder at least 10 days advance written notice of the closing of such Acquisition or Asset Transfer and, if not exercised
prior the closing of such Acquisition or Asset Transfer, this Warrant shall terminate immediately prior to the closing of such
Acquisition or Asset Transfer; provided, however, that if at the closing of such Acquisition or Asset Transfer the Fair
Market Value of one Share exceeds the Warrant Price, then as of such closing this Warrant shall be deemed to have been exercised
in full on a “net exercise” basis pursuant to Section 2(b).


 


8.          No
Stockholder Rights. This Warrant in and of itself shall not entitle the Holder to any voting rights or other rights
as a stockholder of the Company.


 


9.          Lost,
Stolen, Mutilated or Destroyed Warrant. If this Warrant is lost, stolen, mutilated or destroyed, the Company shall,
on such terms as to indemnity or otherwise as it may reasonably impose (which shall, in the case of a mutilated Warrant, include
the surrender thereof), issue a new Warrant of like denomination and tenor as the Warrant so lost, stolen, mutilated or destroyed.
Any such new Warrant shall constitute an original contractual obligation of the Company, whether or not the allegedly lost, stolen,
mutilated or destroyed Warrant shall be at any time enforceable by anyone.


 


10.        Governing
Law. This Warrant and all rights, obligations and liabilities hereunder shall be governed by the laws of the State of
Delaware.


 


11.        Amendment;
Waiver. Any term of this Warrant may be amended or waived with the written consent of the Company and the Series F
Requisite Investors (as defined in the Purchase Agreement); provided, however, if any amendment of this Warrant
by its terms materially and adversely affects the rights or obligations under this Warrant of any Holder then holding securities
purchased under the Purchase Agreement, in a manner different than such amendment affects such rights or obligations of other
Investors, then such amendment shall not be effective with respect to such adversely affected Holder without the written consent
of such adversely affected Holder. Notwithstanding the foregoing, nothing provided in this Section 11 shall limit an individual
Holder’s right to waive or amend any provision of this Warrant on its own behalf.


 


12.        Severability.
Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid under applicable
law, but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall be ineffective
to the extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining provisions
of this Warrant.


 


13.        Counterparts.
This Warrant may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together
shall constitute one and the same instrument.


 


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LEFT BLANK]


 




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In
Witness Whereof, the Company has caused this Warrant to be executed
by its duly authorized officer as of the date first written above.


 


	 	Chimerix, Inc.
	 	 
	 	By:	 
	 	 	Kenneth I. Moch
	 	 	Chief Executive Officer


 


Acknowledged and Accepted:


 


Holder


 


	 	 	 
	 	 	 
	By:	 	 
	 	 	 
	Name:	 	 
	 	 	 
	Title:	 	 
	 	 	 	 


 


[Warrant
Signature page]


 







    	 



    	 



    

 


EXHIBIT A


 


NOTICE OF EXERCISE


 


TO:
Chimerix, Inc.


 


(1)          ̈     The
undersigned hereby elects to purchase ________ Shares (the “Exercise Shares”) of Chimerix, Inc.
(the “Company”) pursuant to the terms of the attached Warrant, and tenders herewith payment of the exercise
price in full, together with all applicable transfer taxes, if any.


 


 ̈     The
undersigned hereby elects to purchase ________ Shares (the “Exercise Shares”) of Chimerix, Inc.
(the “Company”) pursuant to the terms of the net exercise provisions set forth in Section 2(b) of
the attached Warrant, and shall tender payment of all applicable transfer taxes, if any.


 


(2)         Please
issue a certificate or certificates representing said Exercise Shares in the name of the undersigned or in such other name as is
specified below:


 


________________________





(Name)


 ________________________


________________________





(Address)


 





(3)         The
undersigned represents that (i) the aforesaid Exercise Shares are being acquired for the account of the undersigned for investment
and not with a view to, or for resale in connection with, the distribution thereof and that the undersigned has no present intention
of distributing or reselling such shares; (ii) the undersigned is aware of the Company’s business affairs and financial condition
and has acquired sufficient information about the Company to reach an informed and knowledgeable decision regarding its investment
in the Company; (iii) the undersigned is experienced in making investments of this type and has such knowledge and background in
financial and business matters that the undersigned is capable of evaluating the merits and risks of this investment and protecting
the undersigned’s own interests; (iv) the undersigned understands that Exercise Shares issuable upon exercise of this Warrant
have not been registered under the Securities Act of 1933, as amended (the “Securities Act”), by reason
of a specific exemption from the registration provisions of the Securities Act, which exemption depends upon, among other things,
the bona fide nature of the investment intent as expressed herein, and, because such securities have not been registered under
the Securities Act, they must be held indefinitely unless subsequently registered under the Securities Act or an exemption from
such registration is available; (v) the undersigned is aware that the aforesaid Exercise Shares may not be sold pursuant to Rule
144 adopted under the Securities Act unless certain conditions are met and until the undersigned has held the shares for the period
of time prescribed by Rule 144, that among the conditions for use of the Rule is the availability of current information to the
public about the Company and the Company has not made such information available and has no present plans to do so; and (vi) the
undersigned agrees not to make any disposition of all or any part of the aforesaid shares of Exercise Shares unless and until there
is then in effect a registration statement under the Securities Act covering such proposed disposition and such disposition is
made in accordance with said registration statement, or, if reasonably requested by the Company, the undersigned has provided the
Company with an opinion of counsel satisfactory to the Company, stating that such registration is not required.









 




    	1.



    	 



    

 





 


	 	 	 
	(Date)	 	(Signature)
	 	 	 
	 	 	 
	 	 	(Print name)


 




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EXHIBIT B


 


ASSIGNMENT FORM


 


(To assign the foregoing Warrant,
execute this form


and supply required information. Do not use this


form to purchase shares.)


 


For
Value Received, the foregoing Warrant and all rights evidenced thereby are hereby assigned to


 


	Name: 	 
	 	(Please Print)
	Address: 	 
	 	(Please Print)
	 	 	 
	Dated: __________, 20__	 
	 	 	 
	Holder’s	 	 
	Signature: 	 	 
		 	 
	Holder’s	 	 
	Address: 	 	 


 


NOTE: The signature to this Assignment
Form must correspond with the name as it appears on the face of the Warrant, without alteration or enlargement or any change whatever.
Officers of corporations and those acting in a fiduciary or other representative capacity should file proper evidence of authority
to assign the foregoing Warrant.


 




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