EX-10.35



 Exhibit 10.35 
 EMPLOYMENT AGREEMENT 
 Todd M. Snell 

THIS EMPLOYMENT AGREEMENT (the “Agreement”) is entered into this 2nd day of August, 2012 (the “Effective Date”) by
and between NxStage Medical, Inc. (the “Company”) and Todd M. Snell (the “Executive”). 
 WHEREAS, the
Company desires to employ Executive, and Executive desires to be employed by the Company upon the terms and conditions hereinafter set forth; 

NOW, THEREFORE, the parties hereto, intending to be legally bound, hereby agree as follows: 
 1. Employment. The Company hereby agrees to employ Executive, and Executive hereby accepts such employment and agrees to perform Executive’s duties and responsibilities, in accordance with the
terms, conditions and provisions hereinafter set forth. This Agreement shall be effective on the Effective Date and shall continue until terminated in accordance with Section 2 hereof. Nothing in this Agreement shall be construed as giving
Executive any right to be retained in the employ of the Company, and Executive specifically acknowledges that Executive shall be an employee-at-will of the Company, and thus subject to discharge at any time by the Company with or without cause and
without compensation of any nature except as provided in Section 2 below. 
 1.1 Duties and Responsibilities.
Commencing on the Effective Date, Executive shall serve as a Senior Vice President Quality, Regulatory, Compliance & Clinical and shall perform all duties and accept all responsibilities incident to such position as may be reasonably
assigned to Executive by the Company’s Board of Directors (the “Board”) or by the Chief Executive Officer (“CEO”) of the Company. Executive shall be based at the Company’s headquarters in Lawrence, Massachusetts, or
such place or places in the continental United States as the Board shall determine. 
 1.2 Extent of Service. Executive
agrees to use Executive’s best efforts to carry out Executive’s duties and responsibilities under Section 1.1 hereof and, consistent with the other provisions of this Agreement, to devote substantially all of Executive’s business
time, attention and energy thereto. The foregoing shall not be construed as preventing Executive from making passive investments in other businesses or enterprises, provided that Executive agrees not to become engaged in any other business
activity which, in the reasonable judgment of the Board, is likely to interfere with Executive’s ability to discharge Executive’s duties and responsibilities to the Company. 

1.3 Base Salary. For all the services rendered by Executive hereunder, the Company shall pay Executive a base salary (“Base
Salary”) at the annual rate of $290,000.00, less applicable taxes and withholdings, payable bi-weekly in installments at such times as the Company customarily pays its other senior level executives. Executive’s Base Salary shall be
reviewed annually, starting in Q4 of 2013 for appropriate increases by the Board, CEO, or compensation committee pursuant to the normal performance review policies for senior level executives. 

1.4 Incentive Compensation. Executive shall participate in short-term and long-term incentive programs established by the Company
for its senior level executives generally, at levels determined by the Board or the Compensation Committee. Executive’s incentive compensation shall be subject to the terms of the applicable plans and shall be determined based on
Executive’s individual performance and Company performance as determined by the Board or the Compensation Committee. For 2013, the Compensation Committee of the Board has determined that Executive will be entitled to receive incentive
compensation, consistent with the term of the Company’s 2013 bonus plan, of up to 40% of Executive’s Base Salary at target performance based on Executive’s individual performance and Company performance, as determined by the
compensation committee of the Board. Incentive compensation shall be paid in the calendar year immediately following the year to which the incentive compensation relates and may be paid in the form of cash, Company stock or any other form of
consideration deemed appropriate by the Board or the compensation committee. Executive shall not be eligible to participate in the 2012 Corporate Bonus Plan. 
 1.5 Additional Compensation. Executive shall be paid $120,000 in two equal installments in the form of cash on 10/1/2012 and the remainder on 1/1/2013. If the Executive should voluntarily resign or
is terminated for cause as defined in section 2.8(a) within one year from date of issuance, the amount shall be reimbursed to NxStage in full. 
 1.6 Retirement and Welfare Plans. Executive shall participate in employee retirement and welfare benefit plans made available to the Company’s senior level executives as a group or to its
employees generally, as such retirement and welfare plans may be in effect from time to time and subject to the eligibility requirements of the plans. Nothing in this Agreement shall prevent the Company from amending or terminating any retirement,
welfare or other employee benefit plans or programs from time to time as the Company deems appropriate. 
 1.7 Reimbursement
of Expenses; Vacation. Executive may participate in any and all benefit programs, including reimbursement of expenses and vacation, which the Company makes available to its employees from time to time, provided Executive is eligible under (and
subject to all provisions of) the policy and/or plan documents that govern these programs. The Company reserves the right to change, add or cease any particular benefit without notice, in its sole discretion, provided that these
programs shall not be changed or terminated with respect to all employees generally, or as otherwise required by law. For purposes of determining vacation eligibility, Executive will accrue vacation at a 20 day annualized rate. 







 2. Termination. Executive’s employment shall terminate upon the occurrence of any of the
following events: 
 2.1 Termination Without Cause or Resignation for Good Reason Before A Change of Control. 

(a) Subject to Section 2.2 below, if the Company terminates Executive’s employment without Cause (as defined in
Section 2.8) at any time before a Change of Control or Executive resigns for Good Reason (as defined in Section 2.8) at any time before a Change of Control, this Section 2.1 shall apply. 

(b) If Executive’s employment terminates as described in subsection (a) above and Executive executes a written separation
agreement and release within 45-days of the Executive’s termination of employment and does not revoke such release during any statutorily prescribed period, in a form provided by the Company, of any and all claims against the Company and all
related parties with respect to all matters arising out of Executive’s employment by the Company, or the termination thereof (the “Release”), Executive shall be entitled to receive the severance compensation set forth in this
Section 2.1(b), as long as Executive complies with the terms of Executive’s Proprietary Information Agreement (as defined below). The Company shall commence payment of such benefits, to the extent not subject to Section 409A of the
Internal Revenue Code of 1986, as amended, within 10-days from the date the Release becomes irrevocable; provided, however, that if the end of the 45-day plus the revocation period occurs in a year subsequent to the year in which the termination of
employment occurs, payments, to the extent subject to Section 409A, will be made in the subsequent year. Any payments delayed pursuant to this Section shall be paid to the Executive in a lump sum, and all remaining payments due under this
Agreement shall be paid or provided in accordance with the normal payment dates specified for them herein. 
 (i) Executive
shall receive severance payments in an amount equal to .5 times Executive’s annual Base Salary at the rate in effect at the time of Executive’s termination. The severance amount shall be paid in accordance with the Company’s normal
payroll practices over the 6-month period following Executive’s termination of employment (the “Severance Period”). 
 (ii) During the Severance Period, Executive shall be reimbursed by the Company for the monthly cost of medical coverage in effect at the date of Executive’s termination (or generally comparable
coverage) for Executive and, where applicable, Executive’s spouse and dependents (less any required employee payments calculated as if Executive had continued to be an employee). After the Severance Period, Executive shall be responsible for
assuming all costs associated with continuing medical coverage pursuant to COBRA. The COBRA health care continuation coverage period under Section 4980B of the Internal Revenue Code of 1986, as amended (the “Code”), shall run
concurrently with the Severance Period.” If the reimbursement of any COBRA or health insurance premiums would otherwise violate the nondiscrimination rules or cause the reimbursement of claims to be taxable under the Patient Protection and
Affordable Care Act of 2010, together with the Health Care and Education Reconciliation Act of 2010 (collectively, the “Act”) or Section 105(h) of the Code, the reimbursements shall be treated as taxable payments or be subject to
imputed income tax treatment to the extent necessary to eliminate any discriminatory treatment or taxation under the Act or Section 105(h) of the Code. 
 (iii) Stock Options. All outstanding stock options and stock awards held by Executive at the date of Executive’s termination of employment that would have otherwise become vested and
exercisable during the Severance Period will become vested and exercisable during the Severance Period as if Executive had remained employed during the Severance Period. Subject to the provisions of Section 2.2(a) below, Executive shall have up
to ninety (90) days following the expiration of the Severance Period to exercise his vested options or awards (provided that nothing in this Agreement shall extend the right of exercise beyond the earlier of (a) the final exercise or
termination date, as set forth in the respective option or award agreement, or (b) the date of termination, cancellation or exchange of an option as a result of a change in the Company’s capitalization or any reorganization event,
including (i) any merger or consolidation of the Company with or into another entity as a result of which the Common Stock of the Company is converted into or exchanged for the right to receive cash, securities or other property or is
cancelled, (ii) any exchange of all of the Common Stock of the Company for cash, securities or other property pursuant to a share exchange transaction, (iii) any liquidation or dissolution of the Company, or (iv) any similar event).
All options or awards not exercised at the end of this period shall expire and be null and void. All stock option or stock award agreements between the Executive and the Company shall continue in full force and effect except that in the event of any
conflict between this Agreement and either the stock option or award agreement or relevant stock plan, the terms of this Agreement shall prevail, except that this Agreement shall not be construed to limit, in any way, Executive’s rights granted
under Executive’s option or award agreements or relevant stock plan. 
 (iv) Executive shall receive any benefits in
accordance with the terms of any applicable benefit plans and programs of the Company accrued as of the date of the termination. 
 (c) Executive agrees that if Executive fails to comply with Executive’s Proprietary Information Agreement, all payments under this Section 2.1 shall immediately cease. 







 2.2 Termination Without Cause; Resignation for Good Reason After or in Connection With A Change of
Control. 
 (a) If a Change of Control occurs and (i) the Company has terminated Executive’s employment without
Cause within the period of time commencing three (3) months prior to the public announcement by the Company or the acquiring company of such Change of Control and extending until the Change in Control, and unless the Company can reasonably
demonstrate that such termination did not arise in connection with such Change of Control, or (ii) the Company terminates Executive’s employment without Cause at any time upon or after a Change of Control, or (iii) Executive resigns
for Good Reason (as defined in Section 2.8) upon or at any time during the 12-month period following the Change of Control, this Section 2.2 shall apply. 
 (b) If Executive’s employment terminates as described in subsection (a) above and Executive executes a Release within 45-days of the Executive’s termination of employment and does not
revoke such release during any statutorily prescribed period, Executive shall be entitled to receive the severance compensation set forth in this Section 2.2(b), as long as Executive complies with the terms of Executive’s Proprietary
Information Agreement (as defined below). The Company shall commence payment of such benefits, to the extent not subject to Section 409A of the Internal Revenue Code of 1986, as amended, within 10-days from the date the Release becomes
irrevocable; provided, however, that if the end of the 45-day plus the revocation period occurs in a year subsequent to the year in which the termination of employment occurs, payments, to the extent subject to Section 409A, will be made in the
subsequent year. Any payments delayed pursuant to this Section shall be paid to the Executive in a lump sum, and all remaining payments due under this Agreement shall be paid or provided in accordance with the normal payment dates specified for them
herein. Any payments delayed pursuant to this Section shall be paid to the Executive in a lump sum, and all remaining payments due under this Agreement shall be paid or provided in accordance with the normal payment dates specified for them herein.

 (i) Executive shall receive a lump sum severance payment in an amount equal to (A) 1 times Executive’s annual Base
Salary at the rate in effect at the time of Executive’s termination, plus (B) 1 times the greater of (X) Executive’s annual bonus paid by the Company to Executive for the fiscal year preceding Executive’s termination of
employment or (Y) the Executive’s target annual bonus for the then current year. 
 (ii) During the 12-month period
following Executive’s termination of employment (the “CIC Severance Period”), Executive shall be reimbursed by the Company for the monthly cost of medical coverage in effect at the date of Executive’s termination (or generally
comparable coverage) for Executive and, where applicable, Executive’s spouse and dependents (less any required employee payments calculated as if Executive had continued to be an employee). After the CIC Severance Period, Executive shall be
responsible for assuming all costs associated with continuing medical coverage pursuant to COBRA. The COBRA health care continuation coverage period under Section 4980B of the Code, shall run concurrently with the CIC Severance Period. If the
reimbursement of any COBRA or health insurance premiums would otherwise violate the nondiscrimination rules or cause the reimbursement of claims to be taxable under the Patient Protection and Affordable Care Act of 2010, together with the Health
Care and Education Reconciliation Act of 2010 (collectively, the “Act”) or Section 105(h) of the Code, the reimbursements shall be treated as taxable payments or be subject to imputed income tax treatment to the extent necessary to
eliminate any discriminatory treatment or taxation under the Act or Section 105(h) of the Code. 
 (iii) Without limiting
any acceleration of vesting provided for under Executive’s stock option or stock award agreements in connection with a Change of Control, all outstanding stock options and stock awards held by Executive at the date of Executive’s
termination of employment shall become fully vested and exercisable on the date of termination of employment. Executive shall have up to ninety (90) days following his date of termination to exercise his vested options or awards. All options or
awards not exercised at the end of this period shall expire and be null and void. Notwithstanding any other provision of this Agreement but subject to the next succeeding sentence of this subsection (iii), if Executive’s employment is
terminated pursuant to Section 2.2(a)(i) above, then Executive shall have up to ninety (90) days following the Change of Control to exercise his vested options and awards. Nothing in this Agreement shall extend the right of exercise beyond
the earlier of (a) the final exercise or termination date, as set forth in the respective stock option or stock award agreements, or (b) the date of termination, cancellation or exchange of an option as a result of a change in the
Company’s capitalization or any reorganization event, including (i) any merger or consolidation of the Company with or into another entity as a result of which the Common Stock of the Company is converted into or exchanged for the right to
receive cash, securities or other property or is cancelled, (ii) any exchange of all of the Common Stock of the Company for cash, securities or other property pursuant to a share exchange transaction, (iii) any liquidation or dissolution
of the Company, or (iv) any similar event; provided that if any of Executive’s stock options or stock awards would terminate upon a Change of Control because they are not assumed by the successor entity, all of Executive’s outstanding
stock options and stock awards shall become vested immediately prior to the Change of Control, within a timeframe determined by the Compensation Committee of the Company, and reasonably acceptable to Executive, to allow Executive to exercise all of
his options and/or awards prior to the Change of Control; provided that the options or awards not vested immediately prior to the Change of Control shall be subject to the effectiveness of the Change of Control. All stock option and stock awards
agreements between the Executive and the Company shall continue in full force and effect, except that in the event of any conflict between this Agreement and either the stock option or award agreement or relevant stock plan, the terms of this
Agreement shall prevail, except that this Agreement shall not be construed to limit, in any way, Executive’s rights granted under Executive’s stock option or stock award agreements or relevant stock plan. 

(iv) Executive shall receive any benefits accrued in accordance with the terms of any applicable benefit plans and programs of the
Company as of the date of termination. 







 (c) If Executive’s employment is terminated pursuant to Section 2.2(a)(i) above,
then (i) subject to the provisions of Section 2.2(b), Executive shall be entitled to receive the severance compensation set forth in Section 2.2(b) above and the provisions of Section 2.3 below in lieu of the severance
compensation set forth in Section 2.1 above, and (ii) any amounts owed to Executive pursuant to this Section 2.2 shall be offset by the amounts already paid to Executive pursuant to Section 2.1. In addition, to the extent any
stock option has terminated pursuant to the provisions of Section 2.1(b)(iii) above, such termination shall be null and void, and Executive shall have the rights pursuant to Section 2.2(b) above (subject to the provisions of
Section 2.2 (b)(iii) above). 
 (d) Executive agrees that if Executive materially breaches the terms of Executive’s
Proprietary Information Agreement, all payments under this Section 2.2 shall immediately cease. 
 2.3 Voluntary
Termination. Executive may voluntarily terminate Executive’s employment for any reason upon 30 days’ prior written notice. In such event, after the effective date of such termination, except as provided in Sections 2.1 and 2.2 with
respect to a resignation for Good Reason, no further payments shall be due under this Agreement, except that Executive shall be entitled to any benefits accrued as of the employment termination date in accordance with the terms of any applicable
benefit plans and programs of the Company. 
 2.4 Disability. The Company may terminate Executive’s employment if
Executive has been unable to perform the material duties of Executive’s employment for a period of 90 days (which need not be consecutive) in any 12-month period because of physical or mental injury or illness (“Disability”);
provided, however, that the Company shall continue to pay Executive’s Base Salary until the Company acts to terminate Executive’s employment. Executive agrees, in the event of a dispute under this Section 2.4 relating to
Executive’s Disability, to submit to a physical examination by a licensed physician jointly selected by the Board and Executive. If the Company terminates Executive’s employment for Disability, no further payments shall be due under this
Agreement, except that Executive shall be entitled to any benefits accrued as of the employment termination date in accordance with the terms of any applicable benefit plans and programs of the Company. 

2.5 Death. If Executive dies while employed by the Company, the Company shall pay to Executive’s executor, legal
representative, administrator or designated beneficiary, as applicable, any benefits accrued as of the date of death under the Company’s benefit plans and programs. Otherwise, the Company shall have no further liability or obligation under this
Agreement to Executive’s executors, legal representatives, administrators, heirs or assigns or any other person claiming under or through Executive. 
 2.6 Cause. The Company may terminate Executive’s employment at any time for Cause (as defined in Section 2.8) upon written notice to Executive, in which event all payments under this
Agreement shall cease. Executive shall be entitled to any benefits accrued before Executive’s termination in accordance with the terms of any applicable benefit plans and programs of the Company. 

2.7 Notice of Termination. Any termination of Executive’s employment shall be communicated by a written notice of termination
to the other party hereto given in accordance with Section 7. The notice of termination shall (i) indicate the specific termination provision in this Agreement relied upon, (ii) briefly summarize the facts and circumstances deemed to
provide a basis for a termination of employment and the applicable provision hereof, and (iii) specify the termination date in accordance with the requirements of this Agreement. 

2.8 Definitions. 
 (a) “Cause” shall mean any of the following grounds for termination of Executive’s employment: 
 (i) Executive shall have been convicted of, indicted for, or entered a plea of guilty or nolo contendere to, any crime involving moral turpitude or any felony; 

(ii) Executive intentionally and continually fails to perform Executive’s reasonably assigned material duties to the Company (other
than a failure resulting from Executive’s incapacity due to physical or mental illness), which failure has continued for a period of at least 30 days after a written notice of demand for substantial performance, signed by a duly authorized
officer of the Company, has been delivered to Executive specifying the manner in which Executive has failed substantially to perform; or 
 (iii) Executive materially breaches the terms of Executive’s Proprietary Information Agreement. 
 (b) “Change of Control” as used herein, a “Change of Control” shall be deemed to have occurred if: 
 (i) Any “person” (as such term is used in sections 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) becomes a “beneficial owner” (as
defined in Rule 13d-3 under the Exchange Act), directly or indirectly, of securities of the Company representing more than 50% of the voting power of the then 







 
outstanding securities of the Company; provided that a Change of Control shall not be deemed to occur as a result of a transaction in which the Company becomes a subsidiary of another corporation
and in which the stockholders of the Company, immediately prior to the transaction, will beneficially own, immediately after the transaction, shares entitling such stockholders to more than 50% of all votes to which all stockholders of the parent
corporation would be entitled in the election of directors; 
 (ii) The consummation of (A) a merger or consolidation of
the Company with another corporation where the stockholders of the Company, immediately prior to the merger or consolidation, will not beneficially own, immediately after the merger or consolidation, shares entitling such stockholders to more than
50% of all votes to which all stockholders of the surviving corporation would be entitled in the election of directors, (B) a sale or other disposition of all or substantially all of the assets of the Company, provided the sale or disposition
is of more than three quarters (3/4) of the assets of the Company, or (C) a liquidation or dissolution of the Company; or 
 (iii) In any case, a Change of Control must meet the requirements of a change in ownership of the Company or a change in ownership of a substantial portion of the Company’s assets in accordance with
Section 409A(a)(2)(A)(v) of the Code and the applicable provisions of Treasury Regulations § 1.409A-3(i)(5). 
 (c)
“Good Reason” shall mean the occurrence of any of the following events or conditions, unless Executive has expressly consented in writing thereto, or except as a result of Executive’s physical or mental incapacity or as described in
the last sentence of this subsection (c): 
 (i) a material reduction in Executive’s Base Salary or target Bonus before a
Change of Control (as defined above) but in no event less than a 15% reduction; provided however, that such reduction shall not trigger Good Reason if all similarly situated executives are similarly affected by a decrease in Base Salary or target
Bonus; provided further, if such decreases are equal to or greater than 20% of Executive’s Base Salary or target Bonus, Good Reason shall be available to the Executive; 
 (ii) a material reduction in Executive’s Base Salary or target Bonus after a Change of Control (as defined above); 
 (iii) a substantial reduction of Executive’s duties and responsibilities hereunder or diminution of title; or 
 (iv) the Company requires that Executive’s principal office location be moved to a location more than 50 miles from Executive’s principal office location or principal residence (as defined by
Section 217 of the Code) immediately before the change in location (provided that Executive, at the time of termination of employment, does not have a principal residence (as defined by Section 217 of the Code) 50 miles from the
Executive’s principal office); it being understood that Executive’s relocation to Massachusetts shall not trigger a justification for a “Good Reason” termination hereunder. 

(v) For purposes of this Agreement, Good Reason must also meet the requirements for a good reason termination in accordance with
Treasury Regulation § 1.409A-1(n)(2), and any successor statute, regulation and guidance thereto. 
 Notwithstanding the
foregoing, Executive shall not have Good Reason for termination unless Executive gives the Company 30-days advance written notice of termination for Good Reason within 30-days after the event giving rise to Good Reason occurs and the Company does
not correct the action or failure to act that constitutes the grounds for Good Reason, as set forth in Executive’s notice of termination, within 30 days (the “Cure Period”) after the date on which Executive gives written notice of
termination. For purposes of clarification, if the grounds for Good Reason are not corrected by the Company within the Cure Period, the Executive’s termination will be automatic, with no further action on behalf of Executive or the Company, at
the end of the Cure Period. 
 3. Non-Exclusivity of Rights. Nothing in this Agreement shall prevent or limit Executive’s continuing
or future participation in or rights under any benefit, bonus, incentive or other plan or program provided by the Company and for which Executive may qualify; provided, however, that if Executive becomes entitled to and receives the payments
provided for in Section 2 of this Agreement, Executive hereby waives Executive’s right to receive payments under any severance plan or similar program applicable to all employees of the Company. 

4. Employee Proprietary Information, Inventions and Noncompete Provisions. Executive hereby acknowledges his obligations pursuant to his existing
proprietary information, inventions and noncompete provisions attached hereto as Exhibit A (the “Proprietary Information Agreement”), including but not limited to, the obligation to refrain from using or disclosing the proprietary
information of the Company. Executive acknowledges that these obligations shall survive the termination of his employment with the Company, consistent with the terms of the Proprietary Information Agreement. 

5. Acknowledgment. Executive states and represents that he or she has had an opportunity to fully discuss and review the terms of this Agreement,
including Exhibit A, with an attorney. Executive further states and represents that he or she has carefully read this Agreement, including Exhibit A, understands the contents herein, freely and voluntarily assents to all of the terms and conditions
hereof, and signs his name of his own free act. 







 6. Survivorship. The respective rights and obligations of the parties under this Agreement shall
survive any termination of Executive’s employment to the extent necessary to the intended preservation of such rights and obligations. 

7. Mitigation. Executive shall not be required to mitigate the amount of any payment or benefit provided for in this Agreement by seeking other
employment or otherwise and there shall be no offset against amounts due Executive under this Agreement on account of any remuneration attributable to any subsequent employment that Executive may obtain. 

8. Notices. All notices and other communications required or permitted under this Agreement or necessary or convenient in connection herewith
shall be in writing and shall be deemed to have been given when hand delivered or mailed by registered or certified mail, as follows (provided that notice of change of address shall be deemed given only when received): 

If to the Company, to: 
 NxStage Medical, Inc. 
 350 Merrimack Street 

Lawrence, MA 01843 
 Attn: Chief Executive Officer, with a copy to General Counsel 
 If to Executive,
to: 
 Todd M. Snell 
 5 Hyder Street 
 Westborough, MA 01581 

or to such other names or addresses as the Company or Executive, as the case may be, shall designate by notice to each other person entitled to receive
notices in the manner specified in this Section. 
 9. Contents of Agreement; Amendment and Assignment. 

(a) This Agreement, together with the Proprietary Information Agreement, sets forth the entire understanding between the parties hereto
with respect to the subject matter hereof and supersedes any and all prior agreements and understandings concerning Executive’s employment by the Company and cannot be changed, modified, extended or terminated except upon written amendment
approved by the Board and executed on its behalf by a duly authorized officer of the Company and by Executive. 
 (b) All of the
terms and provisions of this Agreement shall be binding upon and inure to the benefit of and be enforceable by the respective heirs, executors, administrators, legal representatives, successors and assigns of the parties hereto, except that the
duties and responsibilities of Executive under this Agreement are of a personal nature and shall not be assignable or delegatable in whole or in part by Executive. The Company shall require that any successor (whether direct or indirect, by
purchase, merger, consolidation, reorganization or otherwise) to all or substantially all of the business or assets of the Company, within 15 days of such succession, expressly to assume and agree to perform this Agreement in the same manner and to
the same extent as the Company would be required to perform if no such succession had taken place. 
 10. Severability. If any provision
of this Agreement or application thereof to anyone or under any circumstances is adjudicated to be invalid or unenforceable in any jurisdiction, such invalidity or unenforceability shall not affect any other provision or application of this
Agreement which can be given effect without the invalid or unenforceable provision or application and shall not invalidate or render unenforceable such provision or application in any other jurisdiction. If any provision is held void, invalid or
unenforceable with respect to particular circumstances, it shall nevertheless remain in full force and effect in all other circumstances. 
 11.
Remedies Cumulative; No Waiver. No remedy conferred upon a party by this Agreement is intended to be exclusive of any other remedy, and each and every such remedy shall be cumulative and shall be in addition to any other remedy given under
this Agreement or now or hereafter existing at law or in equity. No delay or omission by a party in exercising any right, remedy or power under this Agreement or existing at law or in equity shall be construed as a waiver thereof, and any such
right, remedy or power may be exercised by such party from time to time and as often as may be deemed expedient or necessary by such party in its sole discretion. 
 12. Withholding. All payments under this Agreement shall be made subject to applicable tax withholding, and the Company shall withhold from any payments under this Agreement all federal, state and
local taxes as the Company is required to withhold pursuant to any law or governmental rule or regulation. Executive shall bear all expense of, and be solely responsible for, all federal, state and local taxes due with respect to any payment
received under this Agreement. The parties intend that all payments hereunder shall comply with Section 409A of the Code. Executive agrees that the Company may revise the timing or nature of payments in this Agreement to the extent necessary to
comply with Section 409A (although the parties agree that the provisions of this Agreement are not intended to be deferred compensation subject to such section). 







 13. Miscellaneous. This Agreement may be executed in counterparts, each of which is an original. It
shall not be necessary in making proof of this Agreement or any counterpart hereof to produce or account for any of the other counterparts. 

14. Compliance with Section 409A of the Code. 
 14.1 Any applicable reimbursement or direct payment of Executive’s expenses subject to Section 409A of the Code, including without limitation, under Section 1.7 herein, shall be made no
later than the end of the calendar year following the calendar year in which such expense is incurred by the Executive. Any reimbursement or right to direct payment of Executive’s expense in one calendar year shall not affect the amount that
may be reimbursed or paid for in any other calendar year and a reimbursement or payment of Executive’s expense (or right thereto) may not be exchanged or liquidated for another benefit or payment. 

14.2 Notwithstanding any other provision of this Agreement to the contrary, if any amount (including imputed income) to be paid to
Executive pursuant to this Agreement as a result of Executive’s termination of employment is “deferred compensation” subject to Section 409A of the Code, and if Executive is a “Specified Employee” (as defined under
Section 409A of the Code) as of the date of Executive’s termination of employment hereunder, then, to the extent necessary to avoid the imposition of excise taxes or other penalties under Section 409A of the Code, the payment of
benefits, if any, scheduled to be paid by the Employer to Executive hereunder during the first 6-month period following the date of a termination of employment hereunder shall not be paid until the date which is the first business day after six
(6) months have elapsed since the Executive’s termination of employment for any reason other than death. Any deferred compensation payments delayed in accordance with the terms of this Section 14.2 shall be paid in a lump sum after
6-months have elapsed since the Executive’s termination of employment. Such payment shall bear interest at an annual rate equal to the prime rate as set forth in the Eastern edition of the Wall Street Journal on the date of termination, from
the date of termination to the date of payment. Any other payments will be made according to the schedule provided for herein. 

14.3 If any of the benefits set forth in this Agreement are deferred compensation under Section 409A of the Code, any termination of
employment triggering payment of such benefits must constitute a “separation from service” under Section 409A of the Code before, subject to Section 14.2 of this Agreement, distribution of such benefits can commence. For purposes
of clarification, this paragraph shall not cause any forfeiture of benefits on the part of the Executive, but shall only act as a delay until such time as a “separation from service” occurs. 

14.4 It is intended that each installment of the payments and benefits provided under this Agreement shall be treated as a separate
“payment” for purposes of Section 409A of the Code. Neither the Company nor Executive shall have the right to accelerate or defer the delivery of any such payments or benefits except to the extent specifically permitted or required by
Section 409A. 
 14.5 Notwithstanding any other provision of this Agreement to the contrary, the Agreement shall be
interpreted and at all times administered in a manner that avoids the inclusion of compensation in income under Section 409A(a)(1) of the Code. Any provision inconsistent with Section 409A of the Code will be read out of the Agreement. For
purposes of clarification, this Section 14.5 shall be a rule of construction and interpretation and nothing in this Section 14.5 shall cause a forfeiture of benefits on the part of the Executive. 

15. Tax Consequences. The Company makes no guarantee of any tax consequences with respect to this Agreement, any payments set forth herein or any
other payments from the Company to Executive including, without limitation, consequences under Section 409A of the Code or Section 280G of the Code. 
 16. Governing Law. This Agreement shall be governed by and interpreted under the laws of the Commonwealth of Massachusetts without giving effect to any conflict of laws provisions or canons of
construction that construe agreements against the draftsperson. 
 IN WITNESS WHEREOF, the undersigned, intending to be legally bound, have
executed this Agreement as of the date first above written. 
  

	
	NxStage Medical, Inc.
	
	 /s/ Jeffrey H. Burbank

	Jeffrey H. Burbank
	
	President and Chief Executive Officer









 
	
	EXECUTIVE
	
	 /s/ Todd M. Snell

	Todd M. Snell