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## NIH Research Matters

### April 16, 2024 Edition

## 20240416-cholesterol.jpeg

#### Gut bacteria may reduce cholesterol and lower heart disease risk

Researchers pinpointed gut bacteria that affect levels of cholesterol and other compounds linked to heart disease.

## 20240416-stem-cell.jpg

#### Rejuvenating the immune system by depleting certain stem cells

Researchers found that depleting certain stem cells improved the immune systems of aged mice.

## 20240416-bladder.jpeg

#### Sensor monitors bladder fullness

Researchers developed a wireless implantable device that can monitor bladder filling and emptying in real time and send data to a smartphone.

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                      -  20220405-covid.jpg  2022 Research Highlights  —  Human Health Advances   December 20, 2022 —               NIH accomplishments in disease prevention, diagnosis, and treatment include insights into Covid-19 vaccines, advances for type 1 diabetes, and a robotic exoskeleton that helps people walk.  
                      -  20220201-herpes.jpg  2022 Research Highlights — Promising Medical Findings  December 20, 2022 —               NIH findings with potential for enhancing human health include a potential cause of multiple sclerosis, understanding the effects of sleep, and progress towards an HIV vaccine.  
                      -  20221206-ad.jpg  2022 Research Highlights — Basic Research Insights  December 20, 2022 —               Noteworthy NIH advances in basic research include progress in understanding and treating Alzheimer’s disease, discoveries about how the microbiome affects human health, and learning how mosquitos find us.  
                      -  20221213-ai.jpg  Machine learning approach detects brain tumor boundaries  December 13, 2022 —               Data from thousands of patients with glioblastoma worldwide were used to develop an accurate model for detecting tumor boundaries.  
                      -  20221213-hiv.jpg  Progress toward an eventual HIV vaccine  December 13, 2022 —               An experimental HIV vaccine elicited broadly neutralizing antibody precursors in people and may lead to an effective vaccine strategy for HIV.  
                      -  20221213-wound-healing.jpg  Smart bandage improves wound healing in mice  December 13, 2022 —               A smart bandage used wireless power to protect and monitor wounds, provide feedback on tissue health, and encourage healing using electrical current.  
                      -  20221206-pollution-drupal-thumb.jpg  Racial residential segregation and airborne toxic metals  December 6, 2022 —               Air pollution in racially segregated communities contained more toxic metals than in well-integrated communities.  
                      -  20221206-flu.jpg  Using mRNA technology for a universal flu vaccine  December 6, 2022 —               A vaccine using mRNA technology induced an immune response in mice and ferrets against a broad range of different influenza types.  
                      -  20221206-ad.jpg  Alzheimer’s tied to cholesterol, abnormal nerve insulation   December 6, 2022 —               Researchers found evidence that the Alzheimer’s-related gene APOE4 disrupts cholesterol management in the brain and weakens insulation around nerve fibers.  

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### About NIH Research Matters

**Editor:** Harrison Wein, Ph.D.

**Assistant Editors:** Vicki Contie and Brian Doctrow, Ph.D.

***NIH Research Matters***is a weekly update of NIH research highlights reviewed by NIH’s experts. It's published by the Office of Communications and Public Liaison in the NIH Office of the Director.

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