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## NIH Research Matters

### April 16, 2024 Edition

## 20240416-cholesterol.jpeg

#### Gut bacteria may reduce cholesterol and lower heart disease risk

Researchers pinpointed gut bacteria that affect levels of cholesterol and other compounds linked to heart disease.

## 20240416-stem-cell.jpg

#### Rejuvenating the immune system by depleting certain stem cells

Researchers found that depleting certain stem cells improved the immune systems of aged mice.

## 20240416-bladder.jpeg

#### Sensor monitors bladder fullness

Researchers developed a wireless implantable device that can monitor bladder filling and emptying in real time and send data to a smartphone.

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                      -  20200721-covid.jpg  2020 Research Highlights — Human Health Advances  December 22, 2020 —               NIH accomplishments in disease prevention, diagnosis, and treatment include COVID-19 vaccines and treatments, better diagnosis of prostate cancer, and methods for early detection of Alzheimer’s disease.  
                      -  20200929-covid.jpg  2020 Research Highlights —  Promising Medical Findings  December 22, 2020 —               NIH findings with potential for enhancing human health include new approaches to COVID-19, a universal mosquito vaccine, and advances in restoring vision.  
                      -  20200324-covit-19.jpg  2020 Research Highlights —  Basic Research Insights  December 22, 2020 —               Noteworthy NIH advances in basic research include progress in understanding SARS-CoV-2, discovery of an exercise-induced protein that generates new brain cells and improves memory, and a new pain-suppression center in the brain.  
                      -  20201215-dementia.jpg  Financial problems can be sign of dementia onset  December 15, 2020 —               Older adults had problems managing financial obligations up to six years before a diagnosis of Alzheimer’s disease or related dementia.  
                      -  20201215-covid.jpg  Antibodies and T cells protect against SARS-CoV-2  December 15, 2020 —               Monkeys with the highest levels of antibodies against SARS-CoV-2, the virus that causes COVID-19, were best protected against reinfection. Immune cells called T cells also helped prevent reinfection.  
                      -  20201215-cancer.jpg  Stress may awaken dormant cancer cells  December 15, 2020 —               Researchers found that stress may help awaken dormant tumor cells, causing cancer to recur. The findings suggest targets to investigate for preventing cancer relapse.  
                      -  20201208-cancer.jpg  Understanding “exceptional responders” to cancer treatment  December 8, 2020 —               Molecular changes in the tumors of patients who are exceptional responders to cancer treatments may suggest personalized treatment approaches for cancer patients.  
                      -  20201208-hormone.jpg  Hormone suppresses hunger in primates and people  December 8, 2020 —               A hormone called LCN2 suppressed hunger after eating, researchers found, and levels were depressed in people with obesity.  
                      -  20201208-brain.jpg  Molecule guides stem cells to damaged brain tissue  December 8, 2020 —               Scientists altered a molecule that is naturally produced by the body to safely guide stem cells to damaged brain tissue in mice.  

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### About NIH Research Matters

**Editor:** Harrison Wein, Ph.D.

**Assistant Editors:** Vicki Contie and Brian Doctrow, Ph.D.

***NIH Research Matters***is a weekly update of NIH research highlights reviewed by NIH’s experts. It's published by the Office of Communications and Public Liaison in the NIH Office of the Director.

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