Exhibit
10.13


  





LICENSE
AGREEMENT








 


This
License Agreement ("Agreement") is entered into by and between MDNA Life Sciences Inc., a Delaware corporation ("MDNA"),
and Laboratory Corporation of America Holdings, a Delaware corporation ("LabCorp"), as of the 22nd day of
December, 2017 (the "Effective Date").


 


WHEREAS,
MDNA owns the rights to certain intellectual prope1iy that is useful in connection with laboratory testing relating to prostate cancer;
and


 


WHEREAS,
LabCorp is engaged in the business of providing laboratory testing services; and


 


WHEREAS,
the purpose of this Agreement is to set forth the terms by which MDNA will license such intellectual property to LabCorp and its
Affiliates.


 


NOW,
THEREFORE, in consideration of the mutual covenants exchanged herein, MDNA and LabCorp hereby agree to be legally bound as follows: 





 


1.            Definitions.
For purposes of this Agreement, the terms below shall have the meanings set forth below. Additional terms are defined in the preamble
above and throughout the Agreement.


 


"Affiliate"
or "Affiliates" means, with respect to a party to this Agreement, any current or future Entity which controls, is
controlled by, or is under common control with such party. For purposes of this definition and Section 4.2.d. only, "control"
means direct or indirect ownership of at least fifty percent (50%) of the shares or other equity interests of the subject Entity entitled
to vote in the election of directors (or, in the case of an Entity that is not a corporation, for the election of the corresponding managing
authority).


 


"Applicable
Test" means an assay performed by LabCorp or its Affiliate that constitutes a Licensed Service.


 


"Commencement
Date" means the earlier of: (a) one hundred and fifty (150) days after the Effective Date of this Agreement, or (b) the Commercial
Launch Date.


 


"Commercial
Launch Date" means the first date on which LabCorp makes Licensed Services generally available to its customers (excluding research
and development, validation work, or testing performed in connection with clinical studies or clinical trials).


 


"Confidentiality
Agreement" means the Confidentiality Agreement between the parties dated July 28, 2017.


 


"Confidential
Information" has the meaning defined in the Confidentiality Agreement. Without limiting the foregoing, all Net Sales and other
information furnished or disclosed to MDNA by LabCorp in connection with this Agreement shall be considered Confidential Information.


 




    	 		 



    


    










 


"Contract
Quarter" means a three (3) month period commencing on (i) the Commencement Date or the three (3), six (6), or nine (9) month
anniversary of the Commencement Date, or (ii) any annual anniversary of the foregoing thereafter.


 


"Contract
Year" means a period of twelve (12) months beginning on the Commencement Date and each annual anniversary thereof. For example,
the first Contract Year means the period of time commencing on the Commencement Date and continuing for twelve (12) months from the Commencement
Date.


 


"Entity"
means a person, corporation, partnership, association, limited liability company, unincorporated organization, firm, or other entity.


 


"Exclusive
Period" means the period beginning on the Effective Date and continuing for the remainder of the Term, unless terminated earlier
pursuant to Section 2.2.b.


 


"Field"
means the field of prostate cancer identification, screening, and diagnosis in humans using blood.


 


"IVD
Kit" means an in vitro diagnostic product that requires regulatory approval and is sold in a kit form for the purpose of allowing
third parties to perform a test.


 


"LDT"
means a laboratory developed test.


 


"Licensed
Patents" means (a) the patents and patent applications listed on Exhibit A attached hereto and all other applications
claiming priority thereto, specifically relating to the detection of the 3.4kb mitochondrial DNA deletion in human blood; (b) all divisionals,
continuations and continuations-in-part of, and other applications claiming priority to any of the foregoing or from which any of the
foregoing claim priority; (c) all patents issuing from any of the foregoing, including substitutions, reissues, re-examinations, extensions,
registrations, patent term extensions, supplemental protection certificates and renewals of any of the foregoing; and (d) any other patent
applications, patents, or other patent rights owned, licensed, or otherwise controlled by MDNA in the Territory during the Term that
would be useful to LabCorp in performing or selling Licensed Services in the Field, including without limitation patent rights covering
any improvements or modifications made by MDNA to its Prostate Mitomic Test.


 


"Licensed
Service" means any process, method, test or service which, without the license granted in this Agreement, would infringe a Valid
Claim contained in the Licensed Patents in the Territory.


 


"Licensed
Trademark" shall mean the trademark "Mitomic TechnologyTM", which is, and hereafter shall remain, the property
of MDNA.


 


"Milestones"
means the milestone events specified on Exhibit B attached hereto.


 




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"Milestone
Fees" means the milestone fees specified on Exhibit B attached hereto, corresponding to the occurrence of applicable
Milestones, payable in accordance with Section 3.5.


 


"Minimum
Annual Royalties" means the minimum annual royalties set forth on Exhibit C attached hereto (based on the applicable
Contract Year), payable in accordance with Section 3.3.


 


"Minimum
Sales Thresholds" means the amount of Applicable Tests set forth on Exhibit D attached hereto, which LabCorp must sell
in an applicable Contract Year in order to maintain its exclusivity as described in Section 2.2.b.


 


"Net
Sales" means the itemized fee-for-service amounts actually earned by LabCorp or its Affiliates from third parties for performance
of Licensed Services (taking into account discounts, rebates and contractual allowances), less taxes and bad debt as recorded by LabCorp
(up to maximum of 6%) as to its revenues during the applicable period. For purposes of the prior sentence, "earned" means amounts
that are booked (or recognized as income) according to generally accepted accounting principles (GAAP) for accrual basis taxpayers. The
bad debt deduction referenced in this definition is the charge, on a percentage of revenue basis, which LabCorp recognizes in the given
period to maintain the allowance for doubtful accounts at an appropriate level, to estimate the extent to which collection of accounts
receivable will not be possible from customers. MDNA understands and acknowledges that LabCorp does not monitor or charge bad debt expense
on an individual test basis. The Net Sales with respect to Licensed Services when sold in combination with other products, services,
or tests which are not Applicable Tests (collectively, "Non-Royalty-Bearing Items"), shall be that amount determined
by multiplying the Net Sales covering both the Applicable Test and Non-Royalty Bearing Items by an appropriate combination fraction.
The combination fraction shall be a fraction, the numerator of which is the list price of the Applicable Test and the denominator of
which is the aggregate of the list price for both the Applicable Test and Non-Royalty Bearing Items.


 


"Preliminary
Study" means a clinical study that LabCorp intends to conduct following the Effective Date as generally described on Exhibit
E attached hereto.


 


"Term"
means the period beginning on the Effective Date and ending upon expiration or termination of this Agreement (including the Initial
Term, as defined in Section 4.1, and any and all Renewal Terms, as defined in Section 4.1).


 


"Territory" means
the United States of America, and its possessions and territories.


 


"Valid
Claim" means a claim in a patent that has been issued and that has not expired, lapsed, or been declared invalid by a final
order (for which all appeal periods have passed and with respect to which there is no pending appeal) of a court of competent jurisdiction
in the Territory or by the U.S. Patent and Trademark Office.


 




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		2.	License to Licensed Patents.



 


2.1           Grant
and Scope of License. MDNA hereby grants to LabCorp and each of its Affiliates a license to use the Licensed Patents in the Territory
to (i) conduct research and development for commercial purposes in the Field that is limited to testing performed by LabCorp and its
Affiliates in connection with clinical studies or clinical trials for commercial purposes; (b) develop and validate LabCorp's and its
Affiliates' own LDTs for the purposes and indications in the Field that are described in the Licensed Patents; and (c) perform, market,
offer for sale, sell and otherwise commercialize LDTs in the Field. This license does not include the right to make or sell IVD Kits.


 


		2.2	Exclusivity.



 


a.       During
the Exclusive Period, LabCorp's license to the Licensed Patents shall be exclusive in the Territory for the Field. Accordingly, during
the Exclusive Period, MDNA shall not (i) perform, market, offer for sale,
sell, or otherwise commercialize an LDT in the Territory for the Field (whether directly for customers, as a reference laboratory or
send-out service for another clinical laboratory, or otherwise), or (ii) license or otherwise grant any Entity other than LabCorp (and
its Affiliates) the right to use the Licensed Patents to perform, market, offer for sale, sell or otherwise commercialize an LDT in the
Territory for the Field. To the extent MDNA has, prior to the Effective Date, licensed or otherwise granted any Entity (a "Pre-
Existing Licensee") other than LabCorp (and its Affiliates) the right to use the Licensed Patents, it shall have provided any
such Pre-Existing Licensee notice of rescission or termination in advance of the Effective Date, and such prior grant shall not constitute
a breach of this Agreement provided that such notice effectively terminates the rights of such Pre-Existing Licensee within thirty (30)
days after the Effective Date.


 


b.       In
the event LabCorp and its Affiliates fail to sell an amount of Applicable Tests equal to or exceeding the Minimum Sales Thresholds in
any Contract Year of the Term, then MDNA will have the right to terminate the Exclusive Period by providing written notice to LabCorp
within ninety (90) days following the end of such Contract Year. Following termination of the Exclusive Period, LabCorp's license to
the Licensed Patents shall be non- exclusive for the remainder of the Term. For purposes of clarification, LabCorp's failure to meet
the Minimum Sales Thresholds shall not be considered a breach of this Agreement, and MDNA's sole and exclusive remedy for LabCorp's failure
shall be to convert LabCorp's exclusive license to a non-exclusive license, as described herein.


 


2.3          Preliminary
Study. MDNA acknowledges that LabCorp intends to conduct a Preliminary Study at LabCorp's own cost. LabCorp will use
commercially reasonable eff01is to complete its initial validation work within thirty (30) days after the Effective Date of this
Agreement, and the Preliminary Study within one hundred and twenty (120) days after completion of such validation work. In the event
LabCorp elects to publish or publicly present the data generated by LabCorp in the Preliminary Study, LabCorp agrees to give MDNA
prior written notice. If MDNA objects to such publication or presentation within fifteen (15) days of receipt of such written
notice, LabCorp will cooperate by either not publishing or presenting such data, or by making any changes reasonably requested by
MDNA. MDNA shall not publish, publicly present or otherwise disclose any data arising from the Preliminary Study without the prior
written consent of LabCorp, and in the event LabCorp provides such consent, (a) MDNA shall allow LabCorp or its representatives to
participate as co-authors at their own election, and


(b)
LabCorp shall be given appropriate credit in an acknowledgment in such form and substance as is approved by LabCorp.





 




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2.4          Additional
Licensed Patents. MDNA will promptly notify LabCorp in writing of any patent rights other than those listed on Exhibit A that
are owned, licensed, or otherwise controlled by MDNA in the Territory at any time during the Term that may be useful to LabCorp in performing
or selling Licensed Services in the Field, including without limitation any patent rights covering any improvements or modifications
made by MDNA to its Prostate Mitomic Test. All such patent rights will automatically be included within the definition of "Licensed
Patents" and the license granted in Section 2.1 for purposes of this Agreement without additional charge to LabCorp and its Affiliates.


 


	3.	Payments.



 


3.1          Upfront
License Fee. LabCorp will pay MDNA an upfront license fee of Two Hundred and Fifty Thousand Dollars ($250,000.00) within ten (10) days
after the Effective Date.


 


3.2          Commencement
Date License Fee. LabCorp will pay MDNA an additional license fee of Two Hundred and Fifty Thousand Dollars ($250,000.00) within thirty
(30) days after the Commencement Date. For purposes of clarification, (a) this fee will only be due one time even if there are multiple
LDTs (or multiple versions of the same LDT) marketed or sold by LabCorp and its Affiliates, and (b) this fee will not be due if this Agreement
is terminated at any time prior to thirty (30) days after the Commencement Date.


 


3.3          Minimum
Annual Royalties. Within thirty (30) days after the beginning of each Contract Year of the Term, LabCorp agrees to pay MDNA the applicable
Minimum Annual Royalties for that Contract Year. All Minimum Annual Royalties will be fully creditable towards Running Royalties (defined
below) that are payable under this Agreement. For purposes of clarification, even if the Exclusive Period is terminated by MDNA, the
Minimum Annual Royalties will continue to be payable by LabCorp.


 


3.4          Running
Royalties. LabCorp agrees to pay MDNA a running royalty equal to ten percent (10%) of its Net Sales during the Term ("Running
Royalties"), subject to deducting any creditable Minimum Annual Royalties paid by LabCorp as provided above. For purposes of clarification,
no royalty shall be due under this Agreement on any tests performed by LabCorp or its Affiliate using an IVD Kit purchased from MDNA or
a vendor holding a license from MDNA under the Licensed Patents. In addition, in no event shall an Applicable Test require payment of
more than one royalty. LabCorp shall have the right to determine the amount to be billed for Applicable Tests. However, the parties will
meet on a semi-annual basis to discuss the then- current pricing of Applicable Tests, as appropriate based on market conditions. Within
thirty (30) days following the end of each Contract Quarter during the Term, LabCorp will notify MDNA in writing of (i) the total number
of Applicable Tests sold and reported by LabCorp and its Affiliates during the prior Contract Quarter, and (ii) the total Net Sales of
LabCorp and its Affiliates during the prior Contract Quarter. LabCorp shall pay MDNA the Running Royalty payable for such Contract Quarter
(after deducting any credits taken for Minimum Annual Royalties previously paid and being applied to the amount due). All payments due
under this Agreement are specified in, and shall be made in, the legal currency of the United States of America. Conversion of sales
recorded in other currencies to U.S. dollars will be performed in a manner consistent with LabCorp’s normal practices used to prepare its
financial statements consistent with Generally Accepted Accounting Principles, provided that such practices use a widely accepted source
of published exchange rates.


 




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3.5          Milestone
Fees. Within thirty (30) days after the end of an applicable Contract Quarter in which a particular Milestone occurs for the first
time during the Term, LabCorp agrees to pay MDNA the corresponding applicable Milestone Fee. For purposes of clarification, each of the
Milestone Fees shall be payable only one time.


 


3.6          Wire
Payment. LabCorp shall make all payments due to MDNA under this Agreement by wire transfer to:


 


MDNA Life
Sciences, Inc


2054 Vista
Parkway


Suite 400


West Palm
Beach FL 33411


 


Bank of
America NA


222 Broadway


New York,
New York 10038


Account#


Routing#


Swift Code:


 


3.7           No
Other Payments. Except as specified in this Section 3, no other payments shall be due from LabCorp or its Affiliates in exchange for
the rights granted or obligations assumed by MDNA under this Agreement.


 


	4.	Term; Termination.



 


4.1          Initial
Term and Renewal Terms. The initial term of this Agreement will commence on the Effective Date and continue until the expiration
of five (5) Contract Years (the "Initial Term"), unless sooner terminated as provided below. Upon expiration of the
Initial Term, the parties may agree to extend the term of this Agreement for one or more additional periods (each a "Renewal
Term"), subject to agreement on Minimum Sales Thresholds (if the Exclusive Period has not been terminated), Running Royalties,
Minimum Annual Royalties, and Milestone Fees that would apply to such Renewal Term(s).


 


4.2          Termination.
Without limiting any other rights or remedies available to a party, the Term of this Agreement may be terminated:


 




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a.       By
LabCorp immediately upon written notice to MDNA at any time prior to the Commercial Launch Date in the event LabCorp reasonably believes
that the results of the Preliminary Study did not achieve the desired outcomes described on Exhibit E attached hereto;


 


b.       By
LabCorp at any time, for any reason, upon at least one hundred and eighty (180) days prior written notice to MDNA;


 


c.       By
either party because of any material breach of the other party of this Agreement upon thirty (30) days prior written notice; provided,
however, that if such breaching party shall, within the foregoing thirty (30)-day period, cure such breach, then such notice of termination
shall be of no effect; or


 


d.       By
LabCorp immediately upon written notice in the event of a Change of Control whereby an Applicable Competitor (defined below) acquires control
of MDNA. A "Change of Control" means an event as a result of which the holders of the outstanding voting securities
of MDNA or the Entities with the power to direct or cause the direction of the management and policies of MDNA as of the Effective Date,
cease to own a majority of the outstanding voting securities of MDNA or the power to direct or cause the direction of the management
and policies of MDNA. An "Applicable Competitor" means any commercial clinical laboratory which has gross revenues exceeding
$100 million derived from providing diagnostic laboratory services in either the then current year or immediately prior year.


 


	5.	Intellectual Property.



 


5.
I         Issuance and Maintenance of Patents. MDNA agrees that it shall properly prosecute
all patent applications within the Licensed Patents and use reasonable efforts to obtain valid, issued patents based on such applications.
During the Term of this Agreement, MDNA shall submit all filings, make all payments, and take all other actions necessary to maintain
all Licensed Patents as valid, in force and in good standing for the longest possible duration with the


U.S.
Patent and Trademark Office (at its own expense) to avoid premature expiration or termination of such Licensed Patents. MDNA agrees to
promptly provide LabCorp with copies of all Final Actions and Notices of Allowance sent to or received from the U.S. Patent and Trademark
Office with respect to the Licensed Patents.


 


5.2          Enforcement
of Rights. During the Exclusive Period, MDNA agrees that it shall, at its own expense, use reasonable efforts to enforce its rights
with respect to any infringement in the Field in the Territory by a third party of any of the Licensed Patents. Without limiting the
foregoing, in the event MDNA is unsuccessful in persuading an alleged infringer to desist within a reasonable time (not to exceed four
(4) months) after MDNA first becomes aware of the basis for such suit during the Exclusive Period, then (i) MDNA shall negotiate in good
faith with LabCorp on reasonable adjustments to the financial terms of this Agreement (including without limitation potential reductions
to the Running Royalty rate, Minimum Annual Royalties, and Milestone Fees), and (ii) if MDNA fails to have initiated and diligently pursue
an infringement suit within such reasonable period of time, then MDNA shall grant LabCorp and its Affiliates the right to file suit on
its behalf and MDNA agrees to cooperate and provide reasonable assistance to LabCorp and its Affiliates in connection with such suit. LabCorp
and its Affiliates shall have the right to any recovery or damages obtained as a result of a suit brought by LabCorp and its Affiliates
(whether by settlement, judgment or otherwise). MDNA agrees that LabCorp may join MDNA as a party to any suit described in this Section
5.2 as necessary for purposes of establishing standing.


 






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5.3          Notice
of Infringement. MDNA shall notify LabCorp immediately if it becomes aware of any infringement in the Field in the Territory by a third
party of any Licensed Patent during the Exclusive Period. LabCorp shall notify MDNA immediately if it becomes aware of any infringement
in the Field in the Territory by a third party of any Licensed patent during the Exclusive Period.


 


5.4          Use
of the Licensed Trademark. MDNA hereby grants to LabCorp and each of its Affiliates a non-exclusive license to use the Licensed Trademark
in connection with the marketing and sale of LDTs in the Field that are Licensed Services. LabCorp agrees to use commercially reasonable
eff011s · to include in all materials, documents, and/or written information marketed, sold, or otherwise provided by LabCorp with
respect to Licensed Services, a reference that the test was performed using the "Mitomic TechnologyTM." At all times during
the Initial Term and during any Renewal Term, LabCorp shall use all commercially reasonable efforts to use the Licensed Trademark in a
manner that does not derogate from MDNA' s rights to and/or ownership of the Licensed Trademark. As of the Effective Date and for the
duration of the Initial Term and any Renewal Term, MDNA shall own the Licensed Trademark. Immediately upon termination of this Agreement,
LabCorp shall cease and desist any and all use of the Licensed Trademark.


 


6.           Representations
and Warranties.MDNA hereby represents and warrants to LabCorp that:


 





a.            MDNA
has sufficient rights to license the Licensed Patents to LabCorp and its Affiliates as specified in this Agreement;


 


b.            The
Licensed Patents are not subject to any lien, claim, security interest, or encumbrance, except for blanket liens, claims, security interests,
or encumbrances that may be against all or substantially all of the assets of MDNA, which would include the Licensed Patents;


 


c.            This
Agreement (including the license granted hereunder) does not contravene or constitute a default of any agreement or commitment to which
MDNA is bound;


 


d.            To
the best of MDNA's knowledge and belief, there is no material unauthorized use or infringement of the Licensed Patents in the Field in
the Territory;


 


e.            To
the best of MDNA's knowledge and belief, there is no pending or threatened litigation relating to the Licensed Patents;


 


f.            To
the best of MDNA's knowledge and belief, there are no patent or other rights of a third party that would be infringed by LabCorp's or its
Affiliates' performing, selling or otherwise commercializing Licensed Services;


 






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g.            As
of the Effective Date, MDNA has not granted any licenses (or, if granted, has provided notice of rescission or termination of such licenses
that will effectively terminate such license within thirty (30) days after the Effective Date), immunities from suit, or covenants-not-
to-sue to any third parties with respect to the Licensed Patents in the Territory; and


 


h.            As
of the Effective Date, to the best of MDNA's knowledge and belief, the issued Licensed Patents listed on Exhibit A are valid and enforceable.


 


	7.	Confidentiality.



 


7.1          Confidentiality
Agreement. The parties agree that the terms of the Confidentiality Agreement shall apply to any Confidential Information exchanged
by the parties pursuant to this Agreement: provided, however, that the Confidentiality Agreement is hereby deemed amended as follows:


 


a.       the
"Purpose," as defined in the recitals to the Confidentiality Agreement, is hereby expanded to include the purposes of fulfilling
obligations or exercising rights under this Agreement; and


 


b.       the
two (2) year term of the Confidentiality Agreement described in Section 5 of the Confidentiality Agreement is hereby extended to continue
for the Term of this Agreement.


 


7.2          Press
Releases; Publicity. MDNA shall not in any way advertise or publish the fact that MDNA is licensing patents to LabCorp and its Affiliates
without the prior written consent of LabCorp. Notwithstanding the foregoing, the parties acknowledge that they intend to issue a joint
press-release either announcing the relationship between the parties contemplated by this Agreement, or announcing the launch of the
Licensed Services by LabCorp, in a form agreed upon by both parties. MDNA acknowledges that LabCorp has a proprietary interest in its legal
and business name and reputation. Therefore, MDNA agrees that it shall not make reference to or otherwise use LabCorp's name nor shall
MDNA mention or describe this Agreement or its relationship with LabCorp and its Affiliates in any press release, advertising, marketing
and/or promotional materials or other publications or materials without first obtaining the prior written approval of LabCorp. Notwithstanding
the foregoing, the parties agree that MDNA may identify LabCorp as a provider of its own test, independently developed and validated by
LabCorp, that uses the Mitomic Technology, (a) on the MDNA website in a form approved in advance by LabCorp, and (b) in other relevant promotional
materials relating to the Mitomic Technology, if approved in advance by LabCorp.


 


7.3       Remedies.
MDNA acknowledges and agrees that because the violation, breach, or threatened breach of this Section 7 would result in immediate
and irreparable injury to LabCorp, LabCorp shall be entitled, without limitation of remedy, to (i) temporary and permanent injunctive and
other equitable relief restraining MDNA from activities constituting a violation, breach or threatened breach of this Section 7 to the
fullest extent allowed by law, and


(ii)
all such other remedies available at law or in equity, including without limitation the recovery of damages.


 




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7.4         Survival.This
Section 7 shall survive expiration or termination of this Agreement.


 


8.            Assignment
and Benefit. Except as expressly set forth in this Agreement, this Agreement may not be assigned by either party to any third party
without the prior written consent of the other party. Subject to the prior sentence, the rights, duties, and obligations of the parties
under this Agreement shall inure to the benefit and shall be binding upon their respective successors and permitted assigns.


 


9.            Status
of Parties. This Agreement creates no relationship of joint venturers, partners, or principal and agent between the parties. Further,
neither party shall be authorized to act on behalf of, or otherwise bind the other patty.


 


10.          Notices.
Any notice contemplated or required or permitted to be given under this Agreement shall be sufficient if in writing and prepaid and
if (i) delivered personally, (ii) sent registered or certified mail, return receipt requested, (iii) sent by express delivery service
(such as Federal Express) where the recipient must execute its receipt, or (iv) sent by facsimile and immediately confirmed by registered
or certified mail or express delivery, to the parties' respective addresses below, or to such other addresses as either party hereto
may hereafter designate in writing.


 





	
    MDNA:

     

    MDNA Life Sciences Inc. Attn:

    Chief Executive Officer

    2054 Vista Parkway, Suite 400

    West Palm Beach, FL 33411

    Fax: (877) 486-6193

     
	
    LabCorp:

     

    Laboratory Corporation of America Holdings

    Attn: Law Department

    531 South Spring Street

    Burlington, NC 27215

    Fax: (336) 226-3835

     

    with a Copy sent to:

     

    Laboratory Corporation of America Holdings

    Attn: Corporate Development

    500 Perimeter Park Drive, Suite B

    Morrisville, NC 27560, USA



  


11.          Governing
Law. This Agreement shall be construed in accordance with and governed by the internal laws of the State of Delaware without giving
effect to any choice of law rule that would cause the application of the laws of any jurisdiction other than the internal laws of the
State of Delaware to the rights and obligations of the parties.


 


12.          LabCorp
Rights in Event of Bankruptcy Rejection. Notwithstanding any other provision of this Agreement to the contrary, in the event that
MDNA becomes a debtor under the United States Bankruptcy Code (11 U.S.C. §101 et. seq. or any similar law in any other country (the
"Bankruptcy Code")) and rejects this Agreement pursuant to Section 365 of the Bankruptcy Code, (i) the license to the
Licensed Patents described under this Agreement shall be deemed fully retained by and vested in LabCorp as protected intellectual property
rights under Section 365(n)(l)(B) of the Bankruptcy Code and further shall be deemed to exist immediately before the commencement of
the bankruptcy case in which MDNA is the debtor; and (ii) LabCorp shall have all of the rights afforded to non-debtor licensees under
Section 365(n) of the Bankruptcy Code.


 




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13.          Records;
Audits. LabCorp shall keep full, true and accurate records and books of account containing all pa1iiculars that may be necessary for
the purpose of confirming the accuracy of, and calculating, as applicable, all payments to MDNA hereunder (including records of Net Sales),
and any other records reasonably required to be maintained with respect to LabCorp's obligations under this Agreement, for a minimum period
of three (3) years or such longer period as required by Applicable Laws. Upon reasonable prior written notice, MDNA shall have a right
to request an audit of LabCorp in order to confirm the accuracy of the foregoing (an "Audit"), but no more than one (1)
Audit per calendar year. If a third party conducts such Audit on MDNA's behalf, then such third party must be approved by LabCorp and execute
a confidentiality agreement reasonably acceptable to LabCorp. LabCorp shall make personnel reasonably available during regular business hours
to answer queries on all such books and records required for the purpose of the Audit. Any underpayments by LabCorp shall be paid to MDNA
within ten (10) business days of notification of the results of such inspection, unless LabCorp disputes such results. Any overpayments
made by LabCorp shall be refunded by MDNA within ten (10) business days of notification of the results of such inspection. MDNA shall bear
the cost of any such Audit, unless the Audit reveals that the actual amounts payable over the entire period Audited hereunder to be underreported
by LabCorp, by more than ten percent (10%), than the amounts as previously reported by LabCorp, in which case LabCorp will be the reasonable
costs of such Audit.


 


14.          Miscellaneous.
This Agreement may be executed in counterparts in order to provide each party with a fully-executed original hereof. This Agreement may
not be changed, modified or amended except by an agreement in writing signed by both parties. The provisions of this Agreement are hereby
deemed by the parties to be severable, and the invalidity or unenforceability of any one or more of the provisions of this Agreement
shall not affect the validity and enforceability of the remaining provisions thereof. The waiver by any party to this Agreement of any
breach or violation of any provisions of this Agreement by any other party hereto shall not operate as a waiver of any other breach.
Titles and headings of sections of this Agreement are for convenience and reference only and shall not affect the construction of any
provisions of this Agreement. All exhibits attached hereto are hereby incorporated herein by reference. This Agreement reflects the complete
understanding of the parties and constitutes their entire agreement regarding its subject matter, superseding all prior verbal or written
negotiations, representations, agreements, understandings, and statements regarding the subject matter herein.


 


[SIGNATURES
APPEAR ON FOLLOWING PAGE]


 




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IN WITNESS
WHEREOF, the parties have executed this Agreement by signature of their respective duly authorized representatives as of the Effective
Date. 








 





	Laboratory Corporation of America Holdings	 	MDNA Life Sciences Inc.
	 	 	 	 	 
	By:	      	 	By:	/s/ Chris Mitton


 


	Printed Name: Marcia Eisenberg	 	Printed Name: -Chris Mitton
	 	 	 	 
	Title:	CSO SrVP	 	Title: President & CEO




























 










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Exhibit
A


 


Licensed
Patents


 


	Country	 	Patent/
    Publication No.	 	Serial
    No.	 	Filing
    Date	 	Title	 	Assignee	 	Status
	us	 	8,008,008	 	11/975,390	 	10/18/2007	 	Mitochondrial
        Mutations And Rearrangements As A Diagnostic Tool For The Detection Of Sun Exposure,

        Prostate
        Cancer And Other Cancers
	 	Mitomics Inc.	 	Patented
	us	 	Not yet published	 	15/470,175	 	 	 	Mitochondrial
        Mutations And Rearrangements As A Diagnostic Tool For The Detection Of Sun Exposure,

        Prostate
        Cancer And Other Cancers
	 	Mitomics Inc.	 	Pending
	us	 	Not yet published	 	15/690,147	 	8/29/2017	 	Mitochondrial Mutations And Rearrangements As
    A Diagnostic Tool For The Detection Of Sun Exposure, Prostate Cancer And Other Cancers	 	MDNALife Sciences Inc.	 	Pending




    	 		 



    


    

  


Exhibit
B


 


Milestones
and Milestone Fees


 


 


	Milestone#	 	Milestone	 	Milestone
    Fee
	1	 	50,000
    Applicable Tests sold and repo1ied by LabCorp	 	One Million Dollars ($1,000,000.00)
	2	 	300,000
    Applicable Tests sold and repo1ied by LabCorp	 	Two Million, Five Hundred Thousand Dollars
    ($2,500,000.00)
	3	 	600,000
    Applicable Tests sold and repo1ied by LabCorp	 	Two Million, Five Hundred Thousand Dollars
    ($2,500,000.00)
	4	 	900,000
    Applicable Tests sold and repo1ied by LabCorp	 	Two Million, Five Hundred Thousand Dollars
    ($2,500,000.00)




    	 		 



    


    




 


Exhibit
C


 


Minimum
Annual Royalties


 


	Contract Year 1	One Million Dollars ($1,000,000.00)
	Contract Year 2	Two Million Dollars ($2,000,000.00)
	Contract Year 3	Three Million Dollars ($3,000,000.00)
	Contract Year 4	Four Million Dollars ($4,000,000.00)
	Contract Year 5	Five Million Dollars ($5,000,000.00)


 


 


Note: The
Minimum Annual Royalties in the table above shall be prorated for the final Contract Year of the Term, to the extent it is not a full
twelve (12) month period.


 




    	 	2	 



    


    










 


Exhibit
D


 


Minimum
Sales Thresholds


 


 


	Contract Year I	70,000 Applicable Tests
	Contract Year 2	I 00,000 Applicable Tests
	Contract Year 3	200,000 Applicable Tests
	Contract Year 4	250,000 Applicable Tests
	Contract Year 5	300,000 Applicable Tests




    	 	3	 



    


    

 





 


Exhibit
E


 


Preliminary
Study


 


Primary Objectives


		1.	Document analytical
                                            sensitivity, specificity, accuracy, precision and reportable range of the assay for LDT validation.



		2.	Validate the clinical
                                            sensitivity and specificity of the LDT



 


Outcomes


 


LDT Validation


	I.	Using the applicable assay protocol (such
                                            as sample volumes, reagent concentrations and volumes, and cycling parameters), measures
                                            of precision, analytical sensitivity and analytical specificity satisfy applicable regulatory
                                            requirements including CLIA and New York State's Clinical Laboratory Evaluation Program



	2.	Paired sample data between LabCorp
                                 and MDNA is sufficient to provide a bias estimation between the two laboratories and establish LabCorp's
                                 diagnostic cutoff.



	3.	PMT classification concordance
                                  (positive or negative) between LabCorp and MDNA is greater than or equal to 80% of samples. (Each laboratory's
                                  data set will be classified using its own diagnostic cutoff).



 


Clinical
Validation


	1.	Applying LabCorp's diagnostic cutoff to the
                                            data set, validate the clinical sensitivity for clinically significant cancers and specificity
                                            for cancer negative of PMT to be at levels acceptable to LabCorp.



 






    	 	4