Skip to main content
        
        U.S. flag
                An official website of the United States government
                    Here’s how you know
                Here’s how you know**Official websites use .gov**
                        
                        A **.gov** website belongs to an official government organization in the United States.
            **Secure .gov websites use HTTPS**
                        
                        A **lock** (
                        Locked padlock icon
                        ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.Search
    Menu

        Search for Information from NIDDK
            
            Entire Site
                Research & Funding
                Health Information
                News
                About NIDDKSearch

Home
            Research & Funding
                                Expand Research & Funding
                                Current Funding Opportunities
                                                    Research Programs & Contacts
                                                    Human Subjects Research
                                                    Funding Process
                                            Research Training & Career Development
                                                    Funded Grants & Grant History
                                                    Research Resources
                                            Research at NIDDK
                                                    Technology Advancement & Transfer
                                                    Meetings & Workshops
                        Health Information
                                Expand Health Information
                                Health Topics
                                                                                                    Diabetes
                                                    Digestive Diseases
                                                    Kidney Disease
                                                    Weight Management
                                                    Liver Disease
                                                    Urologic Diseases
                                                    Endocrine Diseases
                                                    Diet & Nutrition
                                                    Blood Diseases
                                                    Diagnostic Tests
                                            La información de la salud en español
                                                    Health Statistics
                                                    Healthy Moments Radio Broadcast
                                                    Clinical Trials
                                            For Health Professionals
                                                    Diabetes Discoveries & Practice Blog
                                                    Community Health & Outreach
                        News
                                Expand News
                                News Archive
                                                    For Reporters
                                            Meetings & Workshops
                                                    Media Library
                                            Follow Us
                        About NIDDK
                                Expand About NIDDK
                                Meet the Director
                                                    Offices & Divisions
                                                    Staff Directory
                                                    Budget & Legislative Information
                                            Advisory & Coordinating Committees
                                                    Strategic Plans & Reports
                                                    Research Areas
                                                    FAQs
                                            Jobs at NIDDK
                                                    Visit Us
                                                    Contact Us Home
                    Research & Funding
                    Research Programs & Contacts
                    Accelerating Medicines Partnership® Program for Common Metabolic Diseases (AMP® CMD)

    Related Topics
        Research Programs & Contacts
        Accelerating Medicines Partnership® Program for Common Metabolic Diseases (AMP® CMD)
                Diversity Programs
Show child pages
        Diversity Supplement Program
                Network of Minority Health Research Investigators
                Travel & Scholarship Awards
                Research & Training Opportunities for Students
                BRIDGES Consortium
                DiabDocs National K12 Physician Scientist Career Development Program
                Investigator Award to Support Mentoring of Early Career Researchers from Diverse Backgrounds
                NIDDK Partnerships with Professional Societies
                Helping to Accelerate Research Potential (HARP)
                Small Business Programs
                Translational Research
Show child pages
        Disease Biology
                Target Identification
                Assay Development
                Screening
                Hit to Lead
                Lead Optimization
                Pre-Clinical Development
                Clinical DevelopmentAccelerating Medicines Partnership® Program for Common Metabolic Diseases (AMP® CMD)

NIDDK Participation in NIH’s Accelerating Medicines Partnership (AMP) Program
NIDDK is the NIH partner in the Accelerating Medicines Partnership® program for Common Metabolic Diseases (AMP® CMD). Partnering with biopharmaceutical companies and non-profit organizations, this new public-private partnership, managed through the Foundation for the National Institutes of Health (FNIH), is aimed at identifying promising new targets for six common metabolic diseases: nonalcoholic steatohepatitis, kidney diseases, obesity, cardiovascular diseases, type 2 diabetes/prediabetes, and type 1 diabetes.
NIDDK-funded projects will leverage existing genomic association data and integrate new functional genomic data to achieve the following:
Systematic identification of causal variants at genomic loci associated with common metabolic diseases
    Prioritization of likely effector transcripts functioning at associated genomic loci
    Validation of the role of effector transcripts in disease phenotypes in relevant tissues and cell types
    Generation of pathway networks that incorporate effector transcripts and other genes to clarify their roles in metabolic diseases and to identify common pathways across the diseases
    Creation of data analysis tools to increase usability of large scale functional genomic data generated
    Make all data and analytical tools generated accessible for public use via the online CMD Knowledge PortalAbout AMP CMD
AMP CMD brings together four biopharmaceutical companies with four teams of NIDDK-funded investigators, including a Knowledge Portal team and Data Coordinating Center. The consortium will capitalize on the enormous amounts of existing genomic data and will generate new largescale molecular data to achieve a deep understanding of genes and pathways that underlie metabolic diseases. Using this information, the consortium will identify and integrate datasets to identify potential biotargets and new therapeutic targets.
AMP CMD Partners
**Government**
NIH - NIDDK**Industry**
Amgen
    Eli Lilly and Company
    Novo Nordisk
    Pfizer Inc.**Non-profit Organization**
Foundation for the NIHFunding Opportunities
NIDDK has solicited participation through the following funding opportunities for AMP
Limited Competition for the Accelerating Medicines Partnership (AMP) in Type 2 Diabetes Knowledge Portal (RFA-DK-19-505)
    Understanding the Functional Contributions and Mechanisms of Type 2 Diabetes Disease-associated Variants (RFA-DK-19-012)About NIH's AMP initiative
The Accelerating Medicines Partnership program is a public-private partnership that incorporates NIH, FDA, biopharmaceutical and life science companies, and non-profit organizations across multiple disease-focused projects. The goal of the partnership in each project is to accelerate the identification of new diagnostics and therapies through expertise and resources shared among partners.
The NIH AMP Program Type 2 Diabetes was active from 2014 to 2021 and its outcomes are now part of AMP CMD.
**Accelerating Medicines Partnership and AMP are registered service marks of the U.S. Department of Health and Human Services**    NIDDK Program Staff
        Beena Akolkar, Ph.D.
                    Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 Diabetes
                Norann Zaghloul, Ph.D.
                    Genetics and genomics of Type 2 diabetes and functional genomic studies in Type 2 diabetes and metabolic diseases
Recent Funding Opportunities
                    View More Recent Funding Opportunities
        Posted:
                                4/10/2024
                            PA-24-184
                    Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Required)
                    
                    Summary
                Posted:
                                4/9/2024
                            PA-24-185
                    Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Not Allowed)
                    
                    Summary
                Posted:
                                4/2/2024
                            PAR-24-206
                    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
                    
                    Summary
                Posted:
                                4/1/2024
                            RFA-DK-25-008
                    Diabetes Research Centers (P30 Clinical Trial Optional)
                    
                    Summary
                Posted:
                                3/27/2024
                            NOT-OD-24-078
                    Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research
                    
                    SummaryView More Recent Funding Opportunities
Related Links
NIDDK Active Trials in Diabetes and Endocrine Disease
    View related clinical trials from ClinicalTrials.gov.
    Related Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area.
    View related study sections from the NIH's Center for Scientific Review.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

Meetings & Workshops
    dkNET slider card.
                            dkNET
                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
                    A man presenting at an NIH seminar
                            NIH Regional Seminars on Program Funding and Grants Administration
                                Providing education and training for the next generation of biomedical and behavioral scientist
                    SBIR STTR Logo
                            NIH Small Business (SBIR & STTR) Engage & Connect
                                Stay informed about the latest events, or connect through social media.
                    View All Meetings
                            View all Meetings & Workshops
    View all Meetings & WorkshopsNIH Common Fund
    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
    Planning to Apply? Register Early
    Registration is required at eRA Commons and grants.gov and can take 4 weeks.
        Last Reviewed October 2023 Contact Us
**Hours:** 8:30 a.m. to 5 p.m. ET, Monday - Friday**Email:** healthinfo@niddk.nih.gov**Phone:** +1-800-860-8747**TTY:** +711
Chat
Live Chat Available8:30 a.m - 5 p.m. ETMonday - Friday
Follow Us
LinkedIn
X
Facebook
YouTube
InstagramNIH... Turning Discovery Into Health ®
Privacy Policy
    Freedom of Information Act
    Accessibility
    Disclaimers
    Copyright
    Vulnerability Disclosure Policy
Site Map
    For Staff Only
    Get Email Updates
U.S. Department of Health and Human Services
    National Institutes of Health