Skip to main content
        
        U.S. flag
                An official website of the United States government
                    Here’s how you know
                Here’s how you know**Official websites use .gov**
                        
                        A **.gov** website belongs to an official government organization in the United States.
            **Secure .gov websites use HTTPS**
                        
                        A **lock** (
                        Locked padlock icon
                        ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.Search
    Menu

        Search for Information from NIDDK
            
            Entire Site
                Research & Funding
                Health Information
                News
                About NIDDKSearch

Home
            Research & Funding
                                Expand Research & Funding
                                Current Funding Opportunities
                                                    Research Programs & Contacts
                                                    Human Subjects Research
                                                    Funding Process
                                            Research Training & Career Development
                                                    Funded Grants & Grant History
                                                    Research Resources
                                            Research at NIDDK
                                                    Technology Advancement & Transfer
                                                    Meetings & Workshops
                        Health Information
                                Expand Health Information
                                Health Topics
                                                                                                    Diabetes
                                                    Digestive Diseases
                                                    Kidney Disease
                                                    Weight Management
                                                    Liver Disease
                                                    Urologic Diseases
                                                    Endocrine Diseases
                                                    Diet & Nutrition
                                                    Blood Diseases
                                                    Diagnostic Tests
                                            La información de la salud en español
                                                    Health Statistics
                                                    Healthy Moments Radio Broadcast
                                                    Clinical Trials
                                            For Health Professionals
                                                    Diabetes Discoveries & Practice Blog
                                                    Community Health & Outreach
                        News
                                Expand News
                                News Archive
                                                    For Reporters
                                            Meetings & Workshops
                                                    Media Library
                                            Follow Us
                        About NIDDK
                                Expand About NIDDK
                                Meet the Director
                                                    Offices & Divisions
                                                    Staff Directory
                                                    Budget & Legislative Information
                                            Advisory & Coordinating Committees
                                                    Strategic Plans & Reports
                                                    Research Areas
                                                    FAQs
                                            Jobs at NIDDK
                                                    Visit Us
                                                    Contact Us Home
                    Research & Funding
                    Research Programs & Contacts
                    Cystic Fibrosis Research & Translation Centers

    Related Topics
        Research Programs & Contacts
        Cystic Fibrosis Research & Translation Centers
                Diversity Programs
Show child pages
        Diversity Supplement Program
                Network of Minority Health Research Investigators
                Travel & Scholarship Awards
                Research & Training Opportunities for Students
                BRIDGES Consortium
                DiabDocs National K12 Physician Scientist Career Development Program
                Investigator Award to Support Mentoring of Early Career Researchers from Diverse Backgrounds
                NIDDK Partnerships with Professional Societies
                Helping to Accelerate Research Potential (HARP)
                Small Business Programs
                Translational Research
Show child pages
        Disease Biology
                Target Identification
                Assay Development
                Screening
                Hit to Lead
                Lead Optimization
                Pre-Clinical Development
                Clinical DevelopmentCystic Fibrosis Research & Translation Centers
    CFRTCs provide support for basic, preclinical, and clinical research efforts to advance scientific knowledge and new therapies for CF.
    NIDDK Program Staff
        Thomas Eggerman, M.D., Ph.D.
                    Cystic fibrosis research and translation centers, Cystic Fibrosis basic research and clinical trials, rare metabolic diseases basic and clinical trials, clinical islet transplantation registry; advanced artificial pancreas clinical trials, post COVID-19 new onset diabetes
    Funding for Cystic Fibrosis Research & Translation Centers
The goal of these CF Research and Translation Centers is to support research to develop and test therapies for CF.  Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions or a group of institutions with an established, comprehensive research base in cystic fibrosis.
NIDDK funds Cystic Fibrosis Centers through a P30 mechanism. Please see the CF Application Resources for required tables and addition documentation.
Centers are funded on the following review schedule:
3 Centers January Council 2023
    4 Centers January Council 2020Resources and Services Available from Cystic Fibrosis Research & Translation Centers
The Cystic Fibrosis Research and Translation Centers provide a variety of research resources to facilitate CF research from
basic to the conduct of clinical trials. In addition, there are pilot and feasibility research programs that provide
limited funds for early stage investigations.
Cystic Fibrosis Center Sites
The Cystic Fibrosis Research and Translation Centers provide research services for investigators at their sites as well as
for other investigators at other regional, national and even international sites. These services are quite varied and
include various CF related efforts involving biochemical, cell models, animal models small molecule therapeutic development,
gene vectors and clinical applications.
**University of North Carolina**
**Research Aims:** The UNC CF Center focus includes ion transport physiology, mucin biology, microbiology and animal models.
    **Activities & Services**
    UNC CF Center has Cores including preclinical, cell models, mucous biochemistry and clinical translation.
        Pilot & Feasibility Program**University of Alabama at Birmingham**
**Research Aims:** The UAB CF Center aims are to provide a multi-disciplinary research support for CF basic research and therapy.
    **Activities & Services**
    The UAB CF Center maintains Core facilities available for studies of cell biology, ion transport, animal models and translational aspects of CF research.
        Pilot & Feasibility Program**University of California San Francisco**
**Research Aims:** The UCSF CF Center focus is to develop novel therapies for cystic fibrosis and to enhance many research projects examining the mechanisms of cystic fibrosis lung disease.
    **Activities & Services**
    The UCSF CF Center has Cores including high throughput screening, synthesis, cells and tissues and bioassay.**Seattle Children's/University of Washington**
**Research Aims:** The U of W CF Center focus is clinical-translational science in cystic fibrosis (CF), spanning from early drug development to dissemination into the CF community.
    **Activities & Services**
    The U of W CF Center has Cores including microbiology, genomics, host response and clinical care.
        Pilot & Feasibility Program**University of Iowa**
**Research Aims:** The U of Iowa research aims include gene therapy, animal models and CF related diabetes.
    **Activities & Services**
    The U of Iowa CF Center has Cores including gene vector, animal models, clinical, comparative pathology, cells and tissue.
        Pilot & Feasibility Program**Georgia**
**Research Aims:** The Georgia CF Center research focus includes CF-related diabetes (CFRD), the impact of CF on nutritional status, gastrointestinal function, liver function, (including CF-related liver disease, CFLD), and metabolism, and the relationship between these complications of CF disease and lifestyle/behavioral choices such as diet, exercise, activity and sleep.
    **Activities & Services**
    The Georgia CF Center has Cores including diabetes, GI and Nutrition, clinical research and informatics as well as lifestyle and behavior.
        Pilot & Feasibility Program**Cincinnati Children's Hospital Medical Center (CCHMC)**
**Research Aims:**The Cincinnati Children's CF Center research aims are to strengthen and expand the CF research program at CCHMC with an emphasis on establishing a thematic program of "personalized Medicine for CF".**Activities & Services**
    The Cincinnati Children’s CF Center has Cores including personalized clinical core, personalized model system core, and functional and transcriptional atlas of CF respiratory cells
        Pilot & Feasibility Program
**Dartmouth College**
**Research Aims:** Dartmouth CF Center research aims are to build on a long history of CF-related research in lung infection, inflammation/immunity and translational science, by expanding the capability to investigate host-microbe interactions in the gut, and their impact on gut dysbiosis and overall systemic health of CF-related diabetes patients.
    **Activities & Services**
    The Dartmouth CF Center has Cores including gastrointestinal biology, clinical and translational, and bioinformatics and biostatistics.
        Pilot & Feasibility Program
Related Links
NIDDK Active Trials in Cystic Fibrosis
    View related clinical trials from ClinicalTrials.gov.
    NIH Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area.
    Visit the NIH’s Center for Scientific Review website to search for study sections.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

Meetings & Workshops
    dkNET slider card.
                            dkNET
                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
                    A man presenting at an NIH seminar
                            NIH Regional Seminars on Program Funding and Grants Administration
                                Providing education and training for the next generation of biomedical and behavioral scientist
                    SBIR STTR Logo
                            NIH Small Business (SBIR & STTR) Engage & Connect
                                Stay informed about the latest events, or connect through social media.
                    View All Meetings
                            View all Meetings & Workshops
    View all Meetings & WorkshopsNIH Common Fund
    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
    Planning to Apply? Register Early
    Registration is required at eRA Commons and grants.gov and can take 4 weeks.
        Last Reviewed April 2023 Contact Us
**Hours:** 8:30 a.m. to 5 p.m. ET, Monday - Friday**Email:** healthinfo@niddk.nih.gov**Phone:** +1-800-860-8747**TTY:** +711
Chat
Live Chat Available8:30 a.m - 5 p.m. ETMonday - Friday
Follow Us
LinkedIn
X
Facebook
YouTube
InstagramNIH... Turning Discovery Into Health ®
Privacy Policy
    Freedom of Information Act
    Accessibility
    Disclaimers
    Copyright
    Vulnerability Disclosure Policy
Site Map
    For Staff Only
    Get Email Updates
U.S. Department of Health and Human Services
    National Institutes of Health