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                    Laboratory of Biological Modeling
    Laboratory of Biological Modeling
        
            Photo of Arthur Sherman.Arthur Sherman, Ph.D.
        Chief
            arthur.sherman2@nih.gov

        Mathematicians and physicists applying mathematical modeling to biological problems.
                About the Lab
        
Lab Menu

    Lab Sections
            About the Lab
Lab Sections & Chiefs
    Computational Medicine Section
                    Vipul Periwal, Ph.D.
                Endocrine and Neural Dynamics Section
                    Arthur Sherman, Ph.D.
                Integrative Physiology Section
                    Kevin D. Hall, Ph.D.
                Mathematical Biology Section
                    Carson C. Chow, Ph.D.
Computational Medicine Section
        Vipul Periwal, Ph.D.,
Section Chief
    The Computational Medicine Section integrates data from molecular to physiological scales using Bayesian model selection and ideas from information theory and theoretical physics to investigate integrative metabolism, building up from mitochondrial ATP and free radical production, adipocyte development, and liver regeneration to whole-body predictions.
        Visit Section Staff ListEndocrine and Neural Dynamics Section
        Arthur Sherman, Ph.D.,
Section Chief
    The Endocrine and Neural Dynamics Section applies mathematical modeling to the biophysical basis of insulin secretion in pancreatic beta cells.  The long-term goals are to understand how the membrane dynamics interact with intracellular events to regulate secretion and how failure of this system contributes to diabetes.  We also  generalize lessons from beta cells to other secretory cells and neurons.
        Visit Section PageIntegrative Physiology Section
        Kevin D. Hall, Ph.D.,
Section Chief
    The Integrative Physiology Section investigates how metabolism and body composition adapt in response to a variety of interventions. Experiments are performed in both humans and rodents to better understand the complex mechanisms regulating macronutrient metabolism, body composition, and energy expenditure. Mathematical models are developed to quantitatively describe, explain, integrate, and predict the experimental results.
        Visit Section PageMathematical Biology Section
        Carson C. Chow, Ph.D.,
Section Chief
    The Mathematical Biology Section seeks to understand how processes at the genetic, molecular, and cellular levels determine behavior at the organ, tissue, and whole-body levels. Areas of application include obesity, neural networks, and autism.
        Visit Section Page
    
        Last Reviewed February 2024 Contact Us
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