-  Home 
        -  Research & Funding 
        -  Research Programs & Contacts 
        -  Clinical Research in Type 1 Diabetes 

Research Programs & Contacts
-  Clinical Research in Type 1 Diabetes 
-  Diversity ProgramsShow child pages    -  Diversity Supplement Program 
  -  Network of Minority Health Research Investigators 
  -  Travel & Scholarship Awards 
  -  Research & Training Opportunities for Students 
  -  BRIDGES Consortium 
  -  DiabDocs National K12 Physician Scientist Career Development Program 
  -  Investigator Award to Support Mentoring of Early Career Researchers from Diverse Backgrounds 
  -  NIDDK Partnerships with Professional Societies 
  -  Helping to Accelerate Research Potential (HARP) 
-  Small Business Programs 
-  Translational ResearchShow child pages    -  Disease Biology 
  -  Target Identification 
  -  Assay Development 
  -  Screening 
  -  Hit to Lead 
  -  Lead Optimization 
  -  Pre-Clinical Development 
  -  Clinical Development 

# Clinical Research in Type 1 Diabetes

        Determinants, etiology, progression, prevention, and treatment of Type 1 Diabetes in children and adults.    

The Clinical Research in Type 1 Diabetes program includes studies across the lifespan that address the etiology, pathogenesis, prevention and treatment (medical- and self-management) of type 1 diabetes in youth and adults.  The program also supports research on hypoglycemia in T1D, including clinical studies and basic research using healthy individuals to understand the physiologic mechanisms of hypoglycemia. The program includes investigator-initiated clinical or behavioral studies, large, multi-center clinical trials that are conducted under cooperative agreements or contracts, and secondary analyses of ongoing clinical trials in diabetes and endocrinology.

## NIDDK Program Staff

          -  Beena Akolkar, Ph.D.                     Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 Diabetes                
          -  Guillermo A. Arreaza-Rubín, M.D.                     Diabetes and endocrine disease bioengineering and glucose sensing                
          -  Miranda Broadney, M.D., M.P.H.                     Pediatrics, Pediatric Endocrinology, Clinical Management of Diabetes Mellitus, Insulin Resistance, Pediatric Obesity                
          -  Maureen Monaghan Center, Ph.D., CDCES                      Health Psychology, Behavioral Science, Clinical Management of Diabetes                
          -  Ellen Leschek, M.D.                     Type 1 and type 2 diabetes clinical research                
          -  Hanyu Liang, M.D., Ph.D.                     Hepatic Metabolism; Insulin Resistance; Type 2 Diabetes; Obesity; Bariatric Surgery                
          -  Lisa M. Spain, Ph.D.                     Disease-modifying clinical trials in type 1 diabetes, etiology and pathogenesis of type 1 diabetes                
          -  Theresa Teslovich Woo, Ph.D.                     Human behavior, developmental cognitive neuroscience, and brain-based mechanisms involved in obesity and diabetes                

## Recent Funding Opportunities

View More Recent Funding Opportunities
-  Posted:4/10/2024PA-24-184  Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Required)  Summary 
-  Posted:4/9/2024PA-24-185  Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Not Allowed)  Summary 
-  Posted:4/2/2024PAR-24-206  Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)  Summary 
-  Posted:4/1/2024RFA-DK-24-002  Adaptation of Diabetes Control Technologies for Older Adults with T1D  (R01 Clinical Trial Optional)  Summary 
-  Posted:4/1/2024RFA-DK-25-008  Diabetes Research Centers (P30 Clinical Trial Optional)  Summary 

View More Recent Funding Opportunities

## Related Links

-   Clinical Islet Transplantation Study  
 
 
-   The Environmental Determinants of Diabetes in the Young (TEDDY) Study  
 
 
-   NIDDK Central Repository  
 
 
-   Human Subjects Research  
 
 
-   Type 1 Diabetes Special Statutory Funding Program  
 
 
-    NIDDK Active Trials in Type 1 Diabetes  
View related clinical trials from ClinicalTrials.gov.
 
-    NIH Study Sections  
    Study sections conduct initial peer review of applications in a designated scientific area.    Visit the NIH’s Center for Scientific Review website to search for study sections.    
 

----

## Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

-  Ancillary Studies to Major Ongoing Clinical Studies  to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.    
-  NIDDK Central Repository  for access to clinical resources including data and biospecimens from NIDDK-funded studies.    
-  NIDDK Information Network (dkNET)  for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.    

## Additional Research Programs

### *Research*Training

NIDDK supports the training and career development of medical and graduate students, postdoctoralfellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs

### Diversity

#### Diversity Programs

The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs

### Small Business

#### Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business TechnologyTransfer (STTR) programs.These programs support innovative research conducted by small businesses that has the potential forcommercialization.
Learn about NIDDK Small Business Programs

### Human Subjects*Research*

#### Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research

### Translational*Research*

NIDDK provides funding opportunities and resources to encourage translation of basic discoveriesinto novel therapeutics.
Learn about NIDDK Translational Research Opportunities

## Meetings & Workshops

                                dkNET                            
                                                                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.                                                                                                                    

                                NIH Regional Seminars on Program Funding and Grants Administration                            
                                                                                Providing education and training for the next generation of biomedical and behavioral scientist                                                                                                                    

                                NIH Small Business (SBIR & STTR) Engage & Connect                            
                                                                                Stay informed about the latest events, or connect through social media.                                                                                                                    

                                View all Meetings & Workshops                            

View all Meetings & Workshops

          -    NIH Common Fund  
Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
 
          -    Planning to Apply? Register Early  
Registration is required at eRA Commons and grants.gov and can take 4 weeks.