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                    Research & Funding
                    Funding Process
                    Award Funding Policy
                    2018 Award Funding Policy

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    The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports basic and clinical research on many of the most serious diseases affecting public health.
NIDDK extramural research is organized into 3 programmatic divisions: 1) Diabetes, Endocrinology, and Metabolic Diseases; 2) Digestive Diseases and Nutrition; and 3) Kidney, Urologic, and Hematologic Diseases.
The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, cooperative agreements, career development and training awards, and contracts.
Budget Data
Current Appropriation
NIH is operating at a program level of $ 37.984 billion in FY 2018, an increase of approximately $3.1 billion over the FY 2017 final budget allocations.
NIDDK’s discretionary appropriation for FY 2018 is $1.971 billion. This is an increase of about 5.4% from NIDDK’s appropriation in FY 2017. This figure does not include the Special Type 1 Diabetes appropriation of $150 M that NIDDK oversees on behalf of the Department of Health and Human Services.
Funding Strategy
NIDDK is committed to supporting as many  meritorious competing research grant applications as possible. Consistent with  NIH policy (see NIH Guide Notice NOT-OD-18-180), NIDDK will manage its  portfolio in biomedical research investments in a manner that includes  recognizing applications from and providing special consideration for early  career investigators.
To maximize our available resources, all grant awards will continue to be subject to programmatic adjustments from the National Diabetes and Digestive and Kidney Diseases (NDDK) Advisory Council approved levels. These adjustments take into consideration the overall scientific and technical merit of the grant application, the cost of the proposed research, and other resources available for related research projects.
Funding Guidelines
Competing Awards
For FY 2018 NIDDK is establishing a nominal “payline” for new (Type 1) and renewal or competing continuation (Type 2) R01 applications of 13th percentile. Most R01 applications submitted to Funding Opportunity Announcements that 1) do not have a set-aside funds, 2) have a primary assignment to NIDDK, 3) request less than $500,000 direct costs per year, and 3) score at or better than the 13th percentile will receive an award.  Applications that have NIDDK as a secondary assignment do not benefit from this payline.
R01 applications that do not include therapeutic clinical trials as the primary focus of the research plan requesting $500,000 or more in direct costs for any year will be held to a more stringent pay line – the 8th percentile for both Type 1 and 2 applications.
**Therapeutic Clinical Trial R01 Applications**
Per NOT-DK-18-012, NIDDK  will not apply the more stringent pay line to R01 applications that include  therapeutic clinical trials if the total direct costs (exclusive of F&A on  subcontracts) for five years do not exceed $2.5 million (or $2 million for four  years), even if the direct costs equal or exceed $500,000 in some years. *As indicated above, the more stringent pay line  will continue to be applied for all other R01 applications* (i.e., all applications that do not have a therapeutic clinical trial as the primary  focus of the research plan).
Consistent with NIDDK policy first established in FY 2016, R01 applications received in response to Funding Opportunity Announcements (FOAs) that are PARs will not automatically be considered for funding based on payline/percentile ranking. Scores and additional programmatic factors will be weighed when considering applications received under R01 PAR FOAs for funding.
Please note the following regarding competing awards:
NIDDK will exercise discretion and consider portfolio balance, programmatic importance, and other factors in determining precisely which applications are awarded.
    All grant awards will continue to be subject to programmatic adjustments from the NDDK Advisory Council approved levels.
    These funding guidelines are applicable for applications to be paid in FY 2018. Many applications submitted in FY 2018 (e.g., those submitted in January/February/March for September/October Advisory Council consideration) will usually not be eligible for funding consideration until FY 2019. The funding levels for FY 2019 cannot now be reliably predicted.Early Stage Investigators (ESIs)
Fostering the success of investigators  establishing careers in biomedical research is a high priority of the NIDDK and  NIH. In FY 2018 NIDDK will place special emphasis on supporting ESIs (new  investigators within 10-years of their terminal research degree or medical  residency who have not yet been awarded a substantial, competing NIH research  grant; see ESI FAQs and NIDDK’s New and Early Stage  Investigators page) by establishing a nominal payline for R01 applications  submitted by ESIs at the 18th percentile. In addition, when possible and  appropriate the full period of support recommended will be awarded.
R01s applications submitted by New Investigators who are not also ESIs will have a nominal payline at the 13th percentile (same as the general pay line).
First Competitive Renewal Applications of R01 Grants Awarded to NIDDK ESIs
Consistent with the NIH Next Generation Researchers Initiative, NIDDK seeks to  encourage the stable integration of early career researchers into the  scientific research workforce. In support of this, the nominal payline for  first competitive renewal applications for R01 awards to researchers who were  ESIs when they competed for the initial NIDDK Type 1 R01 award will be 16th percentile  in FY 2018. Only one award per eligible investigator may be considered for this  special payline. If a special payline award is made to an eligible investigator  any other eligible applications from that investigator will be considered for  funding based on the standard nominal payline.
Bridge Support
In cases where a competing renewal application falls near but beyond the nominal payline, NIDDK will continue to consider interim support on a case-by-case basis and provide limited support in selected cases. The goal is to preserve essential research resources pending the re-review of a revised application. NIDDK can choose to award a one- or two-year R56 grant to an R01 application scored outside the payline. These awards provide support for investigators to collect preliminary data and use these data to revise and improve their R01 applications.
Administrative Supplements
NIDDK has prioritized its budget to maintain funding of investigator-initiated grants at the highest possible level. Therefore, the institute has little flexibility to support administrative supplements. Given this prioritization, the number of successful administrative supplement applications will be extremely low and generally limited to rare, unforeseen circumstances (e.g., requests to replace key pieces of equipment following a natural disaster).  In FY2018, NIDDK does not have any special FOAs or Notices soliciting administration supplements to replace old equipment or to purchase shared equipment or to expand the scope of a project by adding funds or restoring an administratively cut year.
Duration of Grant Support
Competing awards are  adjusted to achieve a 4-year average duration for research project grants.  Nevertheless, applications from ESIs, MERIT extensions, program project grants,  and clinical trial grants are generally awarded for the full length of their  recommended project period.
Salaries
The Consolidated  Appropriations Act, 2018, prohibits payments  for salaries under grants and other extramural mechanisms in excess of Executive  Level II previously set at $187,000, and effective January  7, 2018, increased to $189,600.  See NOT-OD-18-137 for  additional information.
Non-competing (Continuation) Awards
Consistent with the NIH Fiscal Policy for  Grant Awards – FY 2018 (see NOT-OD-18-180) non-competing (Type 5)  continuation grants (research and non-research) including those that remain to  be issued in FY 2018 will likely be made at the commitment level indicated on  the Notice of Award (including those that were initially issued at 90% of the  commitment level in FY 2018). Out-year commitments for continuation awards in  FY 2019 and beyond remain unchanged.
Program Project (P01), High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2), and Other Applications with Budgets Greater than $500K
NIDDK has adopted a more stringent funding  practice for awarding program project (P01) grants, High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2),  and other investigator-initiated grant applications with budgets of $500,000 or  more requested direct costs in any one year. Prior approval is required before  submitting an application for review that requests $500,000 or more in direct  costs in any one year. The request to submit such applications should be  received at least three months prior to the proposed submission date. Prior  approval is required for renewal and revised applications as well as new  applications. Please consult with the appropriate NIDDK program staff and visit  the following site for information on research areas supported by NIDDK: https://www.niddk.nih.gov/research-funding/research-programs/.
New (Type 1) and Renewal (competing continuation [Type 2]) program project (P01) applications may request a maximum of $6.25 million in direct costs over five years, excluding the Facilities & Administrative (F&A) costs for subcontracts. In addition to the caps on the amount requested, P01 awards are subject to administrative adjustment from the NDDK Advisory Council approved levels. Also, please note that any P01 grant receiving a competing award in FY 2011 or later will be limited to one subsequent renewal.
HIV/AIDS Research
HIV/AIDS related applications will receive additional  consideration in the context of NIH’s HIV/AIDS research priorities (see NOT-OD-15-137)  as well as programmatic relevance to the NIDDK mission.
        Last Reviewed November 2018 Contact Us
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