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		Search Text: Home/< Back ToThe Science/Laboratory of Basic and Translational Immunology
  Laboratory of Basic and Translational Immunology
    The Laboratory of Basic and Translational Immunology, led by Dr. Parizad Torabi-Parizi, focuses on understanding innate immune cell and effector T cell behavior in peripheral tissues, mechanisms regulating such behavior.
    On This Page
    
          Parizad Torabi-Parizi, M.D.
  Parizad Torabi-Parizi, M.D.
          Tenure Track Investigator
          Email
      Meet the Team
            Contact us
  Senior Investigator Research Interests
            
  Research Interests
              Dr. Torabi-Parizi’s program focuses on understanding innate immune cell and effector T cell behavior in peripheral tissues, mechanisms regulating such behavior, and possible interventions that might modulate these responses to improve host outcomes in the context of critical illness, with a particular emphasis on checkpoint pathways. Her current work includes establishing rodent models of sepsis and acute lung injury that allow for the evaluation of molecular mechanisms of host injury and the introduction of therapeutic interventions to alter outcomes.
  Featured Publications
                Nicotinamide Antagonizes Lipopolysaccharide-Induced Hypoxic Cell Signals in Human Macrophages
            Authors:Curran CS, Dougherty EJ, Cui X, Li Y, Jeakle M, Gamble T, Demirkale CY, Torabi-Parizi P.
                                                                
            J Immunol.
      
                2023 Jun 14:
        Read Publication
                      Effect of low-to-moderate hyperoxia on lung injury in preclinical animal models: a systematic review and meta-analysis
            Authors:Minkove S, Dhamapurkar R, Cui X, Li Y, Sun J, Cooper D, Eichacker PQ, Torabi-Parizi P.
                                                                                                                        
            Intensive Care Med Exp.
      
                2023 Apr 24;11(1):22
        Read Publication
                      Vaccination Ameliorates Cellular Inflammatory Responses in SARS-CoV-2 Breakthrough Infections.
            Authors:Huapaya JA, Higgins J, Kanth S, Demirkale C, Gairhe S, Aboye EA, Regenold D, Sahagun SJ, Pastor G, Swaim D, Dewar R, Rehman T, Highbarger HC, Lallemand P, Laverdure S, Adelsberger J, Rupert A, Li W, Krack J, Teferi G, Kuruppu J, Strich JR, Davey R, Childs
                                                                                                                        
            J Infect Dis.
      
                2023 Jun 28;228(1):46-58
        Read Publication
                      The Role of Semaphorins and Their Receptors in Innate Immune Responses and Clinical Diseases of Acute Inflammation
            Authors:Kanth SM, Gairhe S, Torabi-Parizi P.
                                                                                                                        
            Front Immunol.
      
                2021 May 03;12(672441):
        Read Publication
                      Anti-PD-L1 Therapy Does Not Improve Survival in a Murine Model of Lethal Staphylococcus aureus Pneumonia
            Authors:Curran CS, Busch LM, Li Y, Xizhong C, Sun J, Eichacker PQ, Torabi-Parizi P.
                                                                                                                        
            J Infect Dis.
      
                2021 Dec 15;224(12):2073-2084
        Read Publication
                                View More Publications
  Meet the Team

    Parizad Torabi-Parizi, M.D.

            Parizad Torabi-Parizi, M.D.
                Tenure Track Investigator
                Dr. Parizad Torabi-Parizi earned her undergraduate degree in Chemistry and degree in Medicine from Emory University. She completed her internship and residency training in Internal Medicine at the Johns Hopkins Hospital Osler Training Program. She then completed her fellowship training in Critical Care Medicine at the NIH and is now a Tenure-Track Investigator in the NHLBI.
    
          Contact the lab
    10 Center DriveBethesda, MD 20892United States
        Phone:
                    301-496-6597
                Fax:
  Shreya Kanth, M.D.
    
            Shreya Kanth, M.D.
        

    Staff Clinician

        shreya.kanth@nih.gov
            Colleen Curran, M.S., Ph.D.
        

    Research Biologist

        colleen.curran@nih.gov
            Annie Shen
    
            Annie Shen, B.S.
        

    Postbac IRTA Fellow

        annie.shen@nih.gov Back To Top Link
  

        

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