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                    Polycystic Kidney Disease

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        Disease Biology
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                Pre-Clinical Development
                Clinical DevelopmentPolycystic Kidney Disease
    Research on renal injury from cyst growth that occurs in PKD.
    The Polycystic Kidney Disease (PKD) program advances basic, translational, and clinical research relating to renal injury from cyst growth that occurs in PKD and related ciliopathies affecting the kidney. This program supports experimental approaches to evaluate the mechanisms underlying cystic diseases, including cell and molecular biology, genetics, and both mammalian and nonmammalian models of disease. The portfolio promotes functional, structural, and imaging markers and strategies for diagnosis, early detection, severity, prognosis, and outcomes.
    NIDDK Program Staff
        Christine Maric-Bilkan, Ph.D.
                    Basic Science PKD; Polycystic Kidney Disease Research Resource Consortium; Sex and Gender Differences; Kidney and Urology Fellowships
                Susan R. Mendley, M.D.
                    Clinical and Translational PKD; Polycystic Kidney Disease Research Resource Consortium; Pediatric Kidney Disease; Pediatric Centers of Excellence in Nephrology; and Chronic Kidney Disease
                Deepak Nihalani, Ph.D.
                    O’Brien Kidney Centers; Kidney HIV/AIDS; Clinical Translational Studies; Urology HIV/AIDS
Recent Funding Opportunities
                    View More Recent Funding Opportunities
        Posted:
                                4/3/2024
                            RFA-DK-25-009
                    Kidney Technology Development Research Education Program (R25 - Independent Clinical Trial Not Allowed)
                    
                    Summary
                Posted:
                                4/2/2024
                            PAR-24-206
                    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
                    
                    Summary
                Posted:
                                3/27/2024
                            NOT-OD-24-078
                    Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research
                    
                    Summary
                Posted:
                                3/26/2024
                            NOT-OD-24-079
                    Notice of Special Interest: Womens Health Research
                    
                    Summary
                Posted:
                                3/26/2024
                            RFA-NS-25-012
                    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
                    
                    SummaryView More Recent Funding Opportunities
Related Links
Innovative Science Accelerator (ISAC) Program
    PKD Research Study
    Chronic Renal Insufficiency Cohort (CRIC) Study
    A Prospective Cohort Study of Kidney Disease in Children (CKID)
    United States Renal Data System (USRDS)
    CKD Biomarkers Consortium
    NIDDK Active Trials in Polycystic Kidney Disease
    View related clinical trials from ClinicalTrials.gov.
    NIH Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

Meetings & Workshops
    Web rotator for the Gut Microbiota and Kidney Disease meeting
                            Gut Microbiota and Kidney Disease
                                May 28
-                                                29, 2024
                                                                                    Webinar
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                            dkNET
                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
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                            NIH Regional Seminars on Program Funding and Grants Administration
                                Providing education and training for the next generation of biomedical and behavioral scientist
                    View All Meetings
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    View all Meetings & WorkshopsNIH Common Fund
    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
    Planning to Apply? Register Early
    Registration is required at eRA Commons and grants.gov and can take 4 weeks.
        Last Reviewed October 2023 Contact Us
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