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        News Release
                        April 4, 2024
                    Scientists discover potential treatment approaches for polycystic kidney disease
                    Researchers have shown that dangerous cysts, which form over time in polycystic kidney disease (PKD), can be prevented by a single normal copy of a defective gene. This means the potential exists that scientists could one day tailor a gene therapy to treat the disease. They also discovered that a type of drug, known as a glycoside, can sidestep the effects of the defective gene in PKD. The discoveries could set the stage for new therapeutic approaches to treating PKD, which affects millions worldwide.
                News Release
                        Feb. 27, 2024
                    Bariatric surgery provides long-term blood glucose control, type 2 diabetes remission
                    People with type 2 diabetes who underwent bariatric surgery achieved better long-term blood glucose control compared to people who received medical management plus lifestyle interventions according to a new study supported by the National Institutes of Health.
                News Release
                        Jan. 30, 2024
                    Switching to vegan or ketogenic diet rapidly impacts immune system
                    Researchers at the National Institutes of Health observed rapid and distinct immune system changes in a small study of people who switched to a vegan or a ketogenic (also called keto) diet. Scientists closely monitored various biological responses of people sequentially eating vegan and keto diets for two weeks, in random order.
                News Release
                        Jan. 10, 2024
                    Diabetes in America now available
                    Diabetes in America is the NIDDK’s compilation and assessment of epidemiologic, public health, clinical research, and clinical trial data focused on diabetes. This updated resource, developed by researchers at NIDDK and leading diabetes experts from around the country and world, is a one-stop source for crucial scientific information on diabetes, its complications and treatment, health care utilization, and diabetes prevention in the United States.
                News Release
                        July 19, 2023
                    New atlas of human kidney cells to help unlock kidney disease research
                    A study funded by the NIH created the most comprehensive atlas of the human kidney to advance progress in understanding and treating kidney disease. The Kidney Tissue Atlas marks an important milestone for the multicenter study, called the Kidney Precision Medicine Project (KPMP), which began in 2017 with the aim of improving treatment for kidney disease.
                News Release
                        April 27, 2023
                    Being hospitalized with acute kidney injury may increase risk for rehospitalization and death
                    A study supported by the National Institutes of Health found that people who experienced acute kidney injury (AKI) during a hospitalization, including those admitted with AKI or who developed AKI in the hospital, were more likely to revisit the hospital or die shortly after discharge, compared to people hospitalized without AKI. AKI is a sudden loss of kidney function that usually lasts for a short time. The research, funded by NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), was published in the American Journal of Kidney Diseases.
                News Release
                        March 15, 2023
                    NIH-supported trial shows artificial pancreas improves blood glucose control in young children
                    Artificial pancreas technology improved blood glucose control in young children between ages 2 and 6 with type 1 diabetes, according to the results of the Pediatric Artificial Pancreas (PEDAP) Trial, a 13-week randomized controlled trial conducted at three pediatric diabetes centers across the United States.
                News Release
                        Feb. 7, 2023
                    Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
                    Findings from NIH-supported clinical trial showed early treatment of diabetes slows progression to severe disease, but it did not improve visual acuity compared with treating more severe disease once it developed.
                News Release
                        Jan. 5, 2023
                    New 3-D model offers insights into the role of glucose in a deadly kidney disease
                    A research team supported by the National Institutes of Health has developed a new approach to better understand the biology of polycystic kidney disease (PKD), and often-life-threatening genetic disorder that affects millions worldwide. Scientists combined two ways to model the disorder — organ-in-a-dish and organ-on-a-chip technologies — to show the role of glucose, a sugar commonly found in blood, in forming PKD cysts.
                News Release
                        Dec. 29, 2022
                    Future surge in diabetes could dramatically impact people under 20 in U.S.
                    The number of young people under age 20 with diabetes in the United States is likely to increase more rapidly in future decades, according to a new modeling study published today in Diabetes Care.
                News Release
                        Nov. 2, 2022
                    NIH-funded study finds personalized kidney screening for people with type 1 diabetes could reduce costs, detect disease earlier
                    Taking a personalized approach to kidney disease screening for people with type 1 diabetes (T1D) may reduce the time that chronic kidney disease (CKD) goes undetected, according to a new analysis performed by the Epidemiology of Diabetes Interventions and Complications study group, which is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The finding, published in Diabetes Care, provides the basis for the first evidence-based kidney screening model for people with T1D.
                News Release
                        Sept. 28, 2022
                    Bionic pancreas improves type 1 diabetes management compared to standard insulin delivery methods
                    A device known as a bionic pancreas, which uses next-generation technology to automatically deliver insulin, was more effective at maintaining blood glucose (sugar) levels within normal range than standard-of-care management among people with type 1 diabetes, a new multicenter clinical trial has found.
                News Release
                        Sept. 21, 2022
                    Two popular diabetes drugs outperformed others in large clinical trial
                    In a large clinical trial that directly compared four drugs commonly used to treat type 2 diabetes, researchers found that insulin glargine and liraglutide performed the best of four medications approved by the U.S. Food and Drug Administration to maintain blood glucose levels in the recommended range.
                News Release
                        July 14, 2022
                    A type of ‘step therapy’ is an effective strategy for diabetic eye disease
                    NIH-funded clinical trial finds that starting with a cheaper drug and switching to a more expensive drug as needed leads to good vision outcomes in diabetic macular edema.
                News Release
                        Jan. 20, 2022
                    NIH awards $170 million for precision nutrition study
                    The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country for a new study that will develop algorithms to predict individual responses to food and dietary routines.
                News Release
                        Jan. 18, 2022
                    NIH launches first phase of $9.8 million competition to accelerate development of neuromodulation therapies
                    The National Institutes of Health has launched the first phase of the Neuromod Prize, a $9.8 million competition to accelerate the development of neuromodulation therapies — targeted treatments that adjust nerve activity to improve organ function.
                News Release
                        Dec. 21, 2021
                    Parenting program to prevent obesity in firstborn children benefits siblings
                    An intervention shown to help first-time parents prevent childhood obesity has shown spillover effects in second-born children as well, even without further training for the parents.
                News Release
                        Sept. 23, 2021
                    NIH-supported study suggests alternative to race-based kidney function calculations
                    In a study supported by the National Institutes of Health, researchers propose changing a key measure in kidney disease diagnosis and treatment to eliminate the use of race as a variable, providing a non-biased kidney function test that does not compromise accuracy. The study suggests use of a blood lab test called cystatin C, which does not vary by a person’s race, to replace the current lab test called creatinine, which does.
                News Release
                        Aug. 24, 2021
                    New Research Uncovers Concerning Increases in Youth Living with Diabetes in the U.S.
                    Diagnosed cases of type 1 and type 2 diabetes are surging among youth in the United States. From 2001 to 2017, the number of people under age 20 living with type 1 diabetes increased by 45%, and the number living with type 2 diabetes grew by 95%.
                News Release
                        July 28, 2021
                    Serious complications from youth-onset type 2 diabetes arise by young adulthood
                    People with type 2 diabetes diagnosed during youth have a high risk of developing complications at early ages and have a greater chance of multiple complications within 15 years after diagnosis. The findings are the culmination of a first-of-its-kind trial funded largely by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.
                News Release
                        June 1, 2021
                    NIH launches study to determine best time for gestational diabetes screening
                    GO MOMs, a new study supported by the National Institutes of Health aims to improve gestational diabetes screening and diagnosis by better understanding blood glucose levels throughout pregnancy.
                News Release
                        March 31, 2021
                    Preventive treatment reduces diabetic retinopathy complications
                    In a clinical trial, early treatment with anti-vascular endothelial growth factor (VEGF) injections slowed diabetic retinopathy, a complication of diabetes that causes damage to the blood vessels of the light-sensitive tissue in the retina.
                News Release
                        Feb. 12, 2021
                    Researchers propose that humidity from masks may lessen severity of COVID-19
                    Masks help protect the people wearing them from getting or spreading SARS-CoV-2, the virus that causes COVID-19, but now researchers from the National Institutes of Health have added evidence for yet another potential benefit for wearers: The humidity created inside the mask may help combat respiratory diseases such as COVID-19.
                News Release
                        Jan. 21, 2021
                    NIH study compares low-fat, plant-based diet to low-carb, animal-based diet
                    People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of Health. Led by researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the study compared the effects of the two diets on calorie intake, hormone levels, body weight, and more.
                News Release
                        Jan. 15, 2021
                    NIH scientists identify nutrient that helps prevent bacterial infection
                    Description of the release: Scientists studying the body’s natural defenses against bacterial infection have identified a nutrient—taurine—that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could aid efforts seeking alternatives to antibiotics.
                News Release
                        Jan. 8, 2021
                    Statement on the establishment of the Office of Nutrition Research within the NIH Office of the Director
                    NIH has begun the official transfer of the Office of Nutrition Research (ONR) from NIDDK to the NIH Office of the Director. This reorganization positions ONR to enhance engagement of the NIH Institutes and Centers in implementing the 2020-2030 Strategic Plan for NIH Nutrition Research.
                News Release
                        Dec. 15, 2020
                    Surgical and drug treatment options lead to similar outcomes for diabetic eye disease
                    Surgical and injectable drug approaches are equally effective for treatment of bleeding inside the eye from proliferative diabetic retinopathy, according to a National Institutes of Health-supported clinical study from the DRCR Retina Network.
                News Release
                        Sept. 30, 2020
                    NIH funds first nationwide network to study rare forms of diabetes
                    A nationwide study funded by the National Institutes of Health will seek to discover the cause of several unusual forms of diabetes. Through research efforts at 20 U.S. research institutions, the study aims to discover new forms of diabetes, understand what makes them different, and identify their causes.
                News Release
                        Aug. 26, 2020
                    Artificial pancreas effectively controls type 1 diabetes in children age 6 and up
                    A clinical trial at four pediatric diabetes centers in the United States has found that a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — is safe and effective at managing blood glucose levels in children as young as age six with type 1 diabetes. The trial was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.
                News Release
                        July 24, 2020
                    First-ever research network tackles diabetic foot complications
                    Funded by the National Institutes of Health, six U.S. research institutions are launching the first-ever multicenter network to study diabetic foot ulcers, a common and burdensome complication of diabetes and the leading cause of lower limb amputations in the United States. The Diabetic Foot Consortium (DFC) aims to lay the foundation for a clinical trial network to test how to improve diabetic wound healing and prevent amputations among the 27 million American adults with diabetes.
                News Release
                        June 25, 2020
                    NIH-funded study to recruit thousands of participants to reveal exercise impact at the molecular level
                    In the largest exercise research program of its kind, researchers are poised to collect and turn data from nearly 2,600 volunteers into comprehensive maps of the molecular changes in the body due to exercise.
                News Release
                        June 15, 2020
                    NIH launches analytics platform to harness nationwide COVID-19 patient data to speed treatments
                    The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country.
                News Release
                        June 11, 2020
                    NIH scientists develop blood test to help improve liver cancer screening
                    Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure to certain viruses.
                News Release
                        May 27, 2020
                    NIH releases strategic plan to accelerate nutrition research over next 10 years
                    With a focus on precision nutrition, the 2020-2030 Strategic Plan for National Institutes of Health Nutrition Research reflects input from the nutrition research community and the wide range of nutrition research supported across NIH.
                News Release
                        Feb. 26, 2020
                    NIH announces $1 million prize competition to target global disease diagnostics
                    NIH has launched a $1 million Technology Accelerator Challenge to spur the design and development of non-invasive, handheld, digital technologies to detect, diagnose and guide therapies for diseases with high global and public health impact. The challenge is focused on sickle cell disease, malaria and anemia.
                News Release
                        Jan. 21, 2020
                    Drug increases brown fat activity in healthy women
                    A National Institutes of Health study found that chronic treatment with mirabegron, a drug approved to treat overactive bladder, activated brown fat in a small group of healthy women and had several other beneficial metabolic effects. The research, led by Dr. Aaron Cypess at the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), was published online on January 21 in the Journal of Clinical Investigation.
                News Release
                        Dec. 10, 2019
                    NIH strategic plan details pathway to achieving Hepatitis B cure
                    A new strategic plan from the National Institutes of Health outlines efforts to intensify ongoing HBV research with the goals of developing a cure and improving scientific understanding of the virus while creating improved strategies for screening and treating patients.
                News Release
                        Nov. 14, 2019
                    Bacteriophage therapy may ease severity of alcoholic hepatitis
                    A specific strain of a common bacteria found in most people with alcoholic hepatitis correlates with greater liver disease severity and mortality, according to a new study published in Nature. Alcoholic hepatitis is a serious form of alcohol-associated liver disease, and people with it have high levels of the bacterium Enterococcus faecalis (E. faecalis) in their gut.  The study also found that a novel therapeutic approach that specifically targets the E. faecalis strain lessened alcohol-associated liver disease in mice.
                News Release
                        Nov. 14, 2019
                    NIH adds five Lasker Clinical Research Scholars
                    The National Institutes of Health has selected five scientists as Lasker Clinical Research Scholars, part of a joint initiative with the Albert and Mary Lasker Foundation, to foster the next generation of great clinical scientists. This highly competitive program provides talented, early stage researchers the opportunity to carry out independent clinical and translational research for five to seven years at NIH.
                News Release
                        Oct. 16, 2019
                    Artificial pancreas system better controls blood glucose levels than current technology
                    A multicenter randomized clinical trial evaluating a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — has found that the new system was more effective than existing treatments at controlling blood glucose levels in people with type 1 diabetes.
                News Release
                        Oct. 7, 2019
                    NIH grantees win 2019 Nobel Prize in Physiology or Medicine
                    The 2019 Nobel Prize in Physiology or Medicine has been awarded to National Institutes of Health grantees Gregg L. Semenza, M.D., Ph.D., of Johns Hopkins University, and William G. Kaelin Jr., M.D., of Dana-Farber Cancer Institute for their discoveries of how cells sense and adapt to oxygen availability.
                News Release
                        Oct. 3, 2019
                    NIH funding bolsters rare diseases research collaborations
                    Of an estimated 6,500 to 7,000 known rare diseases, only a fraction – maybe 5% – have U.S. Food and Drug Administration-approved treatments. To increase that percentage, the National Institutes of Health has awarded approximately $31 million in grants in fiscal year 2019 to 20 teams – including five new groups – of scientists, clinicians, patients, families and patient advocates to study a wide range of rare diseases.
                News Release
                        Sept. 26, 2019
                    NIH funds $945 million in research to tackle the national opioid crisis through NIH HEAL Initiative
                    To reverse the opioid crisis that continues to grip the nation, the National Institutes of Health has awarded $945 million in total fiscal year 2019 funding for grants, contracts and cooperative agreements across 41 states through the Helping to End Addiction Long-term Initiative or NIH HEAL Initiative. The trans-NIH research effort aims to improve treatments for chronic pain, curb the rates of opioid use disorder (OUD) and overdose and achieve long-term recovery from opioid addiction.
                News Release
                        Sept. 9, 2019
                    Prolonged antibiotic treatment may alter preterm infants’ microbiome
                    Treating preterm infants with antibiotics for more than 20 months appears to promote the development of multidrug-resistant gut bacteria, suggests a study funded by the National Institutes of Health
                News Release
                        Sept. 9, 2019
                    Scientists triple storage time of human donor livers
                    NIH-funded research project develops new method to preserve human livers for transplantation. Scientists have greatly extended the amount of time human livers can be stored for transplantation by modifying a previous protocol to extend the viability of rat livers.
                News Release
                        Aug. 13, 2019
                    Intensive blood pressure control may slow age-related brain damage
                    In a nationwide study, researchers used magnetic resonance imaging (MRI) to scan the brains of hundreds of participants in the National Institutes of Health’s Systolic Blood Pressure Intervention Trial (SPRINT) and found that intensively controlling a person’s blood pressure was more effective at slowing the accumulation of white matter lesions than standard treatment of high blood pressure. The results complement a previous study published by the same research group which showed that intensive treatment significantly lowered the chances that participants developed mild cognitive impairment.
                News Release
                        Aug. 1, 2019
                    “Wildling” mice could help translate results in animal models to results in humans
                    Researchers at the National Institutes of Health developed a new mouse model, called “wildling”, by implanting laboratory mice embryos into wild mice. The wildlings carried the natural microbiome and pathogens of wild mice and mirrored human immune responses better than standard laboratory mice. The mouse model could improve the translation of research in mice into advances in human health.
                News Release
                        July 19, 2019
                    NIH publishes the largest genomic study on type 2 diabetes in sub-Saharan African populations
                    Researchers show critical association between diabetes and previously unlinked ZRANB3 gene.
                News Release
                        July 12, 2019
                    Moderate calorie restriction in young and middle-aged adults significantly reduces heart and metabolic risk factors independent of weight loss
                    Moderately reducing caloric intake over a period of two years significantly improved cardiometabolic risk factors in young and middle-aged, non-obese adults, according to new findings from the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial. The study is a multicenter randomized controlled trial supported by the National Institute on Aging (NIA) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health.
                News Release
                        June 10, 2019
                    Drug delays type 1 diabetes in people at high risk
                    A treatment affecting the immune system effectively slowed the progression to clinical type 1 diabetes in high risk individuals, according to findings from National Institutes of Health-funded research. The study is the first to show that clinical type 1 diabetes can be delayed by two or more years among people who are at high risk.Show
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