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                    Cryo-Electron Microscopy (Cryo-EM) Core, Multi-Institute (MICEF)

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        Cores & Support Services
        Advanced Light Microscopy & Image Analysis Core
                Clinical Laboratory Core
                Clinical Mass Spectrometry Core
                Computational Biomolecular Magnetic Resonance Core
                Cryo-Electron Microscopy (Cryo-EM) Core, NIDDK
                Cryo-Electron Microscopy (Cryo-EM) Core, Multi-Institute (MICEF)
                Genomics Core
                Human Energy & Body Weight Regulation Core
                Laboratory of Animal Sciences Section
                Mouse CRISPR/Cas9 Genome Editing Facility
                Mouse Metabolism CoreCryo-Electron Microscopy (Cryo-EM) Core, Multi-Institute (MICEF)
    **Jenny E. Hinshaw, Ph.D.****, Director****Huaibin Wang, Ph.D., Technical Director****Ulrich Baxa, Ph.D., Senior Manager****Bertram Canagarajah, Ph.D., Computational Director**
View staff and contact information.
The Multi-Institute Cryo-Electron Microscopy (Cryo-EM) Facility (MICEF) is a collaborative facility administered by the NIDDK. It serves the scientific communities of NHLBI, NIDDK and NINDS. It currently houses two Titan Krios microscopes equipped with GIF Quantum K2 systems, a Glacios and an Aquilos cryoFIB. The facility allows for fully-automated atomic-resolution single-particle data collection using EPU, SerialEM and Leginon and cryo-electron tomography methods including cryoFIB milling and CLEM (correlative light and electron microscopy).
MICEF offers support in planning EM experiments, sample preparation and imaging, using equipment, and analyzing data. The scopes is located in buildings 13 and 50. EM grid plungers, carbon evaporator and glow discharge machines are located in building 8.
Contact Huaibin Wang or Ulrich Baxa to discuss potential projects and to schedule time on the instruments.
**For NIH Staff Only:**Learn more about the Core’s services.
        Last Reviewed June 2023 Contact Us
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