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# Diabetes & Metabolism HIV/AIDS

        Studies on the metabolic complications of HIV infection and treatment, including endocrine and body composition abnormalities.    

The Diabetes and Metabolism HIV/AIDS program supports innovative basic science and clinical research on the role of HIV infection, including relevant host conditions, or antiretroviral therapy (ART) on metabolic and endocrine dysfunction. Specific areas of support include, but are not limited to:
          - Studies to elucidate the mechanisms underlying the effects of HIV and/or ART on metabolism (including glucose, lipid, and skeletal metabolism), body composition, and general endocrine function through basic and clinical research
          - Studies that elucidate novel approaches to prevent or manage diabetes and/or other endocrine disorders in HIV-infected individuals. However, such studies should target pathways unique to the development of these disorders in the context of HIV infection and/or its treatment rather than simply testing treatments accepted in non-HIV-infected individuals
          - Studies that elucidate the interactions between HIV, ART, and/or HIV-associated inflammation and diabetes-related medications to provide a basis for individualized therapy
          - Studies that determine the extent to which HIV and its therapy increase the risk of diabetes and/or other endocrine or metabolic dysfunction and identify factors which augment or ameliorate the risk
          - Studies that discover and validate biomarkers for metabolic and/or endocrine disease progression as a result of HIV infection or its treatment
          - Studies that employ non-invasive or minimally invasive means to assess tissue-specific or whole body metabolic changes in vivo due to HIV infection or therapy

Animal studies will not be considered except for those in non-human primates.

## NIDDK Program Staff

          -  Saul Malozowski, M.D., Ph.D., M.B.A.                     Neuroendocrinology of hypothalamic-pituitary axis, neuropeptide signaling and receptors; hormonal regulation of bone and mineral metabolism; HIV/AIDS-associated metabolic and endocrine dysfunction                
          -  Khoa Nguyen, PharmD                     HIV/AIDS comorbidities, complications, coinfections                
          -  Deepak Nihalani, Ph.D.                     O’Brien Kidney Centers; Kidney HIV/AIDS; Clinical Translational Studies; Urology HIV/AIDS                
          -  Peter Perrin, Ph.D.                     Basic and Translational Mucosal Immunology and Inflammation                

## Recent Funding Opportunities

View More Recent Funding Opportunities
-  Posted:4/10/2024PA-24-184  Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Required)  Summary 
-  Posted:4/9/2024PA-24-185  Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Not Allowed)  Summary 
-  Posted:4/2/2024PAR-24-206  Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)  Summary 
-  Posted:4/1/2024RFA-DK-24-002  Adaptation of Diabetes Control Technologies for Older Adults with T1D  (R01 Clinical Trial Optional)  Summary 
-  Posted:4/1/2024RFA-DK-25-008  Diabetes Research Centers (P30 Clinical Trial Optional)  Summary 

View More Recent Funding Opportunities

## Related Links

-    NIDDK Active Trials in Diabetes and Endocrine Disease  
View related clinical trials from ClinicalTrials.gov.
 
-    NIH Study Sections  
    Study sections conduct initial peer review of applications in a designated scientific area.    Visit the NIH’s Center for Scientific Review website to search for study sections.    
 

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## Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

-  Ancillary Studies to Major Ongoing Clinical Studies  to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.    
-  NIDDK Central Repository  for access to clinical resources including data and biospecimens from NIDDK-funded studies.    
-  NIDDK Information Network (dkNET)  for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.    

## Additional Research Programs

### *Research*Training

NIDDK supports the training and career development of medical and graduate students, postdoctoralfellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs

### Diversity

#### Diversity Programs

The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs

### Small Business

#### Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business TechnologyTransfer (STTR) programs.These programs support innovative research conducted by small businesses that has the potential forcommercialization.
Learn about NIDDK Small Business Programs

### Human Subjects*Research*

#### Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research

### Translational*Research*

NIDDK provides funding opportunities and resources to encourage translation of basic discoveriesinto novel therapeutics.
Learn about NIDDK Translational Research Opportunities

## Meetings & Workshops

                                dkNET                            
                                                                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.                                                                                                                    

                                NIH Regional Seminars on Program Funding and Grants Administration                            
                                                                                Providing education and training for the next generation of biomedical and behavioral scientist                                                                                                                    

                                NIH Small Business (SBIR & STTR) Engage & Connect                            
                                                                                Stay informed about the latest events, or connect through social media.                                                                                                                    

                                View all Meetings & Workshops                            

View all Meetings & Workshops

          -    NIH Common Fund  
Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
 
          -    Planning to Apply? Register Early  
Registration is required at eRA Commons and grants.gov and can take 4 weeks.