PI: Jaramillo Zuluaga, Andres Title: Implementing strategies for Building Capacity in Research Administration at 

CIDEIM, and subsequent dissemination within Colombia and the Latin American 

region

Received: 07/31/2019 FOA: PAR18-335 Council: 01/2020

Clinical Trial:Not Allowed

Competition ID: FORMS-E FOA Title: Global Infectious Disease Research Administration Development Award 

for Low-and Middle-Income Country Institutions (G11-Clinical Trial Not Allowed)

1 G11 AI152214-01 Dual: Accession Number: 4334176

IPF: 2474901 Organization: CENTRO INTERNACIONAL (CIDEIM)

Former Number: Department: 

IRG/SRG: ZAI1 AMC-D (J1) AIDS: N Expedited: N

Subtotal Direct Costs Animals: N New Investigator: 

(excludes consortium F&A) Humans: N Early Stage Investigator: 

Year 1: Clinical Trial: N

Year 2: Current HS Code: 10

HESC: N

Senior/Key Personnel: Organization: Role Category: 

Andres Jaramillo Zuluaga CORPORACION CENTRO PD/PI

INTERNACIONAL DE 

ENTRENAMIENTO E INVESTIG

Cindy Montero CORPORACION CENTRO Co-Investigator

INTERNACIONAL DE 

ENTRENAMIENTO E INVESTIG

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OMB Number: 4040-0001

Expiration Date: 10/31/2019

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

APPLICATION FOR FEDERAL ASSISTANCE 3. DATE RECEIVED BY STATE State Application Identifier

SF 424 (R&R)

1. TYPE OF SUBMISSION* 4.a. Federal Identifier

❍ Pre-application ● Application ❍ Changed/Corrected b. Agency Routing Number

Application

2. DATE SUBMITTED Application Identifier c. Previous Grants.gov Tracking Number

5. APPLICANT INFORMATION Organizational DUNS*: 

Legal Name*: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Department:

Division:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

ZIP / Postal Code*:

Person to be contacted on matters involving this application

Prefix: First Name*: Andres Middle Name: Last Name*: Jaramillo Suffix: 

Position/Title:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

ZIP / Postal Code*:

Phone Number*: Fax Number: Email: 

6. EMPLOYER IDENTIFICATION NUMBER (EIN) or (TIN)* 44-4444444

7. TYPE OF APPLICANT* W: Non-domestic (non-US) Entity

Other (Specify):

Small Business Organization Type ❍ Women Owned ❍ Socially and Economically Disadvantaged

8. TYPE OF APPLICATION* If Revision, mark appropriate box(es).

● New ❍ Resubmission ❍ A. Increase Award ❍ B. Decrease Award ❍ C. Increase Duration

❍ Renewal ❍ Continuation ❍ Revision ❍ D. Decrease Duration ❍ E. Other (specify) :

Is this application being submitted to other agencies?* ❍Yes ●No What other Agencies?

9. NAME OF FEDERAL AGENCY* 10. CATALOG OF FEDERAL DOMESTIC ASSISTANCE NUMBER

National Institutes of Health TITLE:

11. DESCRIPTIVE TITLE OF APPLICANT'S PROJECT*

Implementing strategies for Building Capacity in Research Administration at CIDEIM, and subsequent dissemination within Colombia and the

Latin American region

12. PROPOSED PROJECT 13. CONGRESSIONAL DISTRICTS OF APPLICANT

Start Date* Ending Date* 00-000

05/01/2020 10/31/2021

 Page 1
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

SF 424 (R&R) APPLICATION FOR FEDERAL ASSISTANCE Page 2

14. PROJECT DIRECTOR/PRINCIPAL INVESTIGATOR CONTACT INFORMATION

Prefix: First Name*: Andres Middle Name: Last Name*: Jaramillo Zuluaga Suffix: 

Position/Title: Coordinator Research Promotion and Developmen

Organization Name*: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Department:

Division:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

ZIP / Postal Code*:

Phone Number*: Fax Number: Email*: 

15. ESTIMATED PROJECT FUNDING 16. IS APPLICATION SUBJECT TO REVIEW BY STATE

EXECUTIVE ORDER 12372 PROCESS?*

a. YES ❍ THIS PREAPPLICATION/APPLICATION WAS MADE

a. Total Federal Funds Requested* AVAILABLE TO THE STATE EXECUTIVE ORDER 12372

b. Total Non-Federal Funds* $0.00 PROCESS FOR REVIEW ON:

c. Total Federal & Non-Federal Funds* DATE:

d. Estimated Program Income* $0.00 b. NO ● PROGRAM IS NOT COVERED BY E.O. 12372; OR

❍ PROGRAM HAS NOT BEEN SELECTED BY STATE FOR

REVIEW

17. By signing this application, I certify (1) to the statements contained in the list of certifications* and (2) that the statements herein

are true, complete and accurate to the best of my knowledge. I also provide the required assurances * and agree to comply with

any resulting terms if I accept an award. I am aware that any false, fictitious, or fraudulent statements or claims may subject me to

criminal, civil, or administrative penalties. (U.S. Code, Title 18, Section 1001)

● I agree*

* The list of certifications and assurances, or an Internet site where you may obtain this list, is contained in the announcement or agency specific instructions.

18. SFLLL or OTHER EXPLANATORY DOCUMENTATION File Name: 

19. AUTHORIZED REPRESENTATIVE

Prefix: First Name*: Nancy Middle Name: Last Name*: Gore Saravia Suffix: Ph.D

Position/Title*: Director

Organization Name*: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Department:

Division:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

ZIP / Postal Code*:

Phone Number*: Fax Number: Email*: 

Signature of Authorized Representative* Date Signed*

Nancy Saravia 07/31/2019

20. PRE-APPLICATION File Name: Mime Type:

21. COVER LETTER ATTACHMENT File Name: Mime Type:

Contact PD/PI: Jaramillo Zuluaga, Andres Page 2
Contact PD/PI: Jaramillo Zuluaga, Andres Table of Contents 

424 R&R and PHS-398 Specific

Table Of Contents

SF 424 R&R Cover Page............................................................................................................1

Table of Contents...................................................................................................................3

Performance Sites.....................................................................................................................4

Research & Related Other Project Information......................................................................5

Project Summary/Abstract(Description)..............................................................................6

Project Narrative....................................................................................................................7

Facilities & Other Resources................................................................................................8

Research & Related Senior/Key Person................................................................................15

Research & Related Budget Year - 1......................................................................................23

Research & Related Budget Year - 2......................................................................................26

Budget Justification................................................................................................................29

Research & Related Cumulative Budget...............................................................................31

PHS398 Cover Page Supplement...........................................................................................32

PHS 398 Research Plan...........................................................................................................34

Specific Aims........................................................................................................................35

Research Strategy................................................................................................................36

PHS Human Subjects and Clinical Trials Information......................................................46

Bibliography & References Cited.......................................................................................47

Letters of Support................................................................................................................48

 Page 3
OMB Number: 4040-0010

Expiration Date: 10/31/2019

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335. Received Date:

2019-07-31T17:26:48.000-04:00

Project/Performance Site Location(s)

Project/Performance Site Primary Location ❍ I am submitting an application as an individual, and not on behalf of

a company, state, local or tribal government, academia, or other type of

organization.

CORPORACION CENTRO INTERNACIONAL Organization Name: DE ENTRENAMIENTO E INVESTIG

Duns Number:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

Zip / Postal Code*:

Project/Performance Site Congressional District*: 00-000

Project/Performance Site Location 1 ❍ I am submitting an application as an individual, and not on behalf of

a company, state, local or tribal government, academia, or other type of

organization.

CORPORACION CENTRO INTERNACIONAL Organization Name: DE ENTRENAMIENTO E INVESTIG

DUNS Number:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

Zip / Postal Code*:

Project/Performance Site Congressional District*:

Additional Location(s) File Name:

Contact PD/PI: Jaramillo Zuluaga, Andres Page 4
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335. Received Date:

2019-07-31T17:26:48.000-04:00

OMB Number: 4040-0001

Expiration Date: 10/31/2019

RESEARCH & RELATED Other Project Information

1. Are Human Subjects Involved?* ❍ Yes ● No

1.a. If YES to Human Subjects

 Is the Project Exempt from Federal regulations? ❍ Yes ❍ No

If YES, check appropriate exemption number: 1 2 3 4 5 6 7 8

If NO, is the IRB review Pending? ❍ Yes ❍ No

IRB Approval Date:

Human Subject Assurance Number

2. Are Vertebrate Animals Used?* ❍ Yes ● No

2.a. If YES to Vertebrate Animals

Is the IACUC review Pending? ❍ Yes ❍ No

IACUC Approval Date:

Animal Welfare Assurance Number

3. Is proprietary/privileged information included in the application?* ❍ Yes ● No

4.a. Does this project have an actual or potential impact - positive or negative - on the environment?* ❍ Yes ● No

4.b. If yes, please explain:

4.c. If this project has an actual or potential impact on the environment, has an exemption been authorized or an ❍ Yes ❍ No

environmental assessment (EA) or environmental impact statement (EIS) been performed?

4.d. If yes, please explain:

5. Is the research performance site designated, or eligible to be designated, as a historic place?* ❍ Yes ● No

5.a. If yes, please explain:

6. Does this project involve activities outside the United States or partnership with international ● Yes ❍ No

collaborators?*

6.a. If yes, identify countries: COLOMBIA

6.b. Optional Explanation:

Filename

7. Project Summary/Abstract* Project_summary.pdf

8. Project Narrative* Project_narrative.pdf

9. Bibliography & References Cited Bibliography_References.pdf

10.Facilities & Other Resources Facilities_and_Resources.pdf

11.Equipment

Contact PD/PI: Jaramillo Zuluaga, Andres Page 5
PROJECT SUMMARY

The Centro Internacional de Entrenamiento e Investigaciones Medicas, CIDEIM, is recognized by 

COLCIENCIAS as a research center within the National System of Science, Technology and Innovation of 

Colombia. CIDEIM originated in Colombia in 1961 as an International Center for Medical Research and Training 

awarded to Tulane University by the United States National Institutes of Health and hosted by Colombia as a 

bilateral Technical Assistance Mission. Successive renewals of this program were followed by funding through 

the US NIAID ICIDR program until 1989. In 1990 at the initiative of COLCIENCIAS, CIDEIM was established as 

a Colombian non-profit foundation and in 1991, successfully competed for a Tropical Medicine Research Center 

TMRC award from the US NIAID. Since then, CIDEIM investigators have developed collaborative research and 

training programs with U.S. universities through subawards within projects supported by NIAID and the Fogarty 

International Center, as well as receiving direct awards from the US NIAID. Our current NIAID funding includes 

a TMRC U19 award and sub-award within a U19 award to the University of Connecticut, which have increased 

our institutional role in, and responsibility for the management of USNIAID grants. 

The overall goal of this project is to strengthen the capacity of CIDEIM to develop and implement 

institutional policies and practices for grants management that are compliant with NIH guidelines and 

requirements for administration of NIH grants, and to share this capacity with other institutions in the region. To 

achieve this goal, we will first address critical gaps in CIDEIM grants administration for current and future grants 

funded by the USNIH, by training CIDEIM management leaders at Yale University. Senior administrators trained 

in the U.S. will then transfer and implement these policies and practices including oversight of updated NIH 

guidelines, in CIDEIM. Second, we will design, implement and evaluate an internal training plan, curriculum and 

materials that will provide the bases for institutionalization of sustainable grants management and administration 

capacity through continuing education and updating of training in accordance with changes in NIH guidelines. 

This training curriculum and corresponding materials will be adapted for external training and transfer of capacity 

to other institutions in Colombia and the region. Our management leaders and their teams will review and adjust 

Institutional policies, procedures and standard operating procedures (SOPs) to meet good management 

practices in compliance with NIH requirements throughout the pre-award, award and post award phases of the 

natural history of programs and projects. Adaptation of training to internal and external online access and 

development of an in-house grant tracking system will promote sustainability of these practices. 

Contact PD/PI: Jaramillo Zuluaga, Andres Project Summary/Abstract Page 6
PROJECT NARRATIVE

The mission of CIDEIM is to reduce the impact of infectious diseases and thereby improve the quality of life of 

those affected. In pursuing this mission, NIAID support has been fundamental to our research and training for 

prevention and control of transmissible diseases. Training of CIDEIM management leaders in the 

administration of USNIH grants will be sustainably implemented in CIDEIM and shared with other national and 

regional institutions, thereby benefitting current and future NIAID supported projects and research priorities, 

and optimizing the investment of NIH.

Contact PD/PI: Jaramillo Zuluaga, Andres Project Narrative Page 7
CIDEIM FACILITIES AND OTHER RESOURCES 

GOVERNANCE AND OPERATION 

CIDEIM has established external and internal advisory committees, as well as institutional review boards (IRBs), 

to define policies, instruments and mechanisms to ensure compliance with national and international standards 

and regulations for biomedical research. The committees include: Board of Directors, Science and Research 

Training Advisory Committee and the Ethical Review Committee. In addition, internal operations are supported 

by Directive, Scientific, Authorship and Training Committees. Independent external audit of financial 

management is conducted permanently since 1990 when CIDEIM was instituted as a Colombian non-profit 

foundation. 

Board of Directors: The Board of Directors is the governing body of CIDEIM. The principal function of the Board 

is to guide and to promote the organization in the fulfillment of its mission. The Board of Directors operates in 

compliance with the legal guidelines for non-profit organizations and the statutes of the institution, names and 

receives the reports of the external auditor, and the reports of the Director. The members of the Board of 

Directors include leaders in the scientific, clinical, academic, productive, and science and technology policy 

arenas in Colombia. 

Executive Committee: This committee is constituted by the leaders of the research Units and the Director. This 

committee participates in the governing responsibility of CIDEIM together with the Board of Directors in 

developing strategic plans and policies, policy decisions, and their implementation. 

Science and Research Training Advisory Committee: This committee includes the participation of the 

Director of CIDEIM and leading external scientists and directors of national university post graduate programs 

in biomedical sciences. The principal function of this committee is to provide insight and guidance in scientific 

and technical scope, and identify opportunities and challenges for research innovation in accordance with their 

collective knowledge and experience. Daniel Colley, Director for Tropical and Emerging Global Diseases at the 

University of Georgia, with a distinguished career in parasitology dealing especially with the immunology of 

schistosomiasis and Chagas’ disease, is the current Chair of the Committee. This committee recently convened 

in CIDEIM in September of 2017. 

Scientific Committee: This Committee is constituted by the Director, leaders and coordinators of each research 

and support unit. The principal function of the committee is to assure the scientific standards of the research 

program, define the research priorities and promote the scientific and technological development of the 

institution. 

Training committee: The Training Committee was instituted at CIDEIM as a strategy to support higher 

education institutions in the country, in particular graduate programs and the young researcher program as well 

as undergraduate students that want to carry out their thesis in CIDEIM ́s areas of research. One of the main 

functions of this committee is the follow-up and oversight of the training program defined for each trainee in biannual follow-up meetings. The committee also promotes and coordinates internships in clinical research, and 

promotes courses, seminars and workshops. 

Authorship Committee: This ad-hoc committee is responsible for assurance of adherence to internal standards 

and policy for authorship of the communication of research results deriving from the projects of CIDEIM 

investigators and their collaborators. The committee promotes and facilitates compliance with internal and 

external norms through internal and external peer review of the communications to be presented in professional 

meetings or submitted for publication. The committee is also responsible for updating authorship standards in 

accordance with those of the international scientific community, including ethical standards and relevant 

processes for presenting and publishing intellectual material. CIDEIM publication and authorship policy adheres 

to the guidelines of the International Committee of Medical Journal Editors

Ethical Review Committee for Protection of Human Subjects: The constitution of the CIDEIM Ethical Review 

Committee for Protection of Human Subjects adheres to universal guidelines that stipulate the importance of 

participation by different professional groups, institutions and the community. The IRB consists of 8 members, 7 

external members with vote and one institutional member without vote. This committee is guided by national and 

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 8
international guidelines as follows: 1) the Colombian National Resolution 8430/93, which establishes the 

scientific, technical, and administrative norms and guidelines for health research; 2) the National Resolution 

2378/2008 which establishes good clinical practices; 3) the principles of the World Medical Assembly presented 

in the Declaration of Helsinki revised version 2013; 4) the International Ethical Guidelines for Biomedical 

Research Involving Human Subjects developed by the Council for International Organizations of Medical 

Sciences (CIOMS revised version 2016) and 5) the Code of Federal Regulations Title 45 Part 46, for the 

protection of Human Subjects of NIH of June 18th, 1991.CIDEIM has Federal Wide Assurance approval by the 

Office for Human Research Protection (OHRP; FWA # ) valid through November 16, 2021. 

Institutional Research Compliance and Oversight: Diverse research support units including the biostatistics 

and data management unit, clinical research unit, research ethics office, administrative unit and the Direction 

are involved in compliance and oversight in accordance with their functions and expertise. Compliance with 

regulatory, legal and financial requirements is managed by the administrative unit under the authority of the 

Director. Scientific, technical and ethical compliance is managed by the data management and biostatistics unit, 

the clinical research unit, research ethics office and the Direction, which together support investigators and 

research staff in understanding good research practices and standards and their application to research 

activities. CIDEIM has developed policies and procedures in terms of the ethical conduct of research, assurance 

of participant confidentiality, ethical review and approval of research proposals and protocols, monitoring of 

projects and reporting of adverse events and scientific integrity including research misconduct, conflict of interest, 

authorship and publication, and material transfer agreements. Institutionalization of compliance procedures and 

good research practices is promoted and monitored in collaboration with the Training Unit. 

ADMINISTRATIVE UNIT 

The following support processes are managed by this unit. 

Financial Management: Since 2010, the Financial Management office of CIDEIM works collaboratively with 

the Accounts Department of ICESI University to track all grant expenditures and develop financial status reports 

for each project, both for institutional purposes and funding agencies. This new arrangement allows the 

Financial Manager, Mrs. Luz Divia Villa, APC (authorized public accountant) to focus on the monitoring and 

troubleshooting of project accounts, and the development of financial strategies for the institution. 

The Financial team uses the accounting software UNO-EE (Sistema Integrado de Información Empresarial), 

and uses the payroll and health software UNO85C, which allows integrated analysis of data regarding 

accounting, financial, purchasing, salary, health and other benefits for a portfolio of projects in different 

currencies. Additionally internal Apps have been developed to manage purchases and travel logistics which 

have facilitated the internal operation, control of activities and services. Since 2015, CIDEIM has adopted the 

International Financial Reporting Standard (IFRS). 

CIDEIM manages financial resources though the national banking system in Bancolombia and Banco de 

Occidente. International transactions in foreign currencies are conducted through Bancolombia Internacional 

and its subsidiary in Panama City, “Bancolombia Panama S.A”. 

The Financial Manager coordinates presentation of relevant internal reports to project PIs and the Board of 

Directors, as well as external reports for funding agencies, accounting records to the Chamber of Commerce 

and federal and state tax returns. In addition, the Financial Manager interacts with the External Auditor, Gonzalo 

Millán Associates, which conducts monthly day-long monitoring visits and comprehensive audits every 

trimester. The External Auditor also provides continuous assistance to the financial team regarding tax 

regulations and issues and accounting procedures. 

Human Resources: The Human Resources office coordinates activities related to development of job 

descriptions and announcements, candidate interviewing and selection, hiring and payroll. This office maintains 

and updates employee files and promotes the organization and conduct of employee safety and welfare 

activities as well as access to benefits. 

Quality Assurance: The Quality Assurance Office disseminates key information regarding institutional, 

national and international quality requirements and ensures that quality initiatives in the different areas and 

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 9
units of CIDEIM are integrated. CIDEIM is GCP certified by INVIMA (national institute for oversight of 

medications and food products) and has a Quality Management System that responds to the requirements for 

health research in Colombia such as: habilitation of health services, management of human samples and 

biological collections, and access to genetic and biological resources, among others. 

Purchasing: The Purchasing Office negotiates, in close partnership with CIDEIM investigators, the acquisition, 

importation and nationalization of all necessary materials and equipment. The Purchasing Officer also 

maintains price estimate databases which inform the development of research proposal budgets. Recently, 

CIDEIM has developed and implemented a user-friendly application accessible via the institutional intranet that 

expedites purchase requisitions. 

Maintenance: The Maintenance Office, which employs a full time coordinator and a full-time repair technician, 

conducts regular prevention maintenance of medical and laboratory equipment, as well as all activities 

regarding computer maintenance, including the installation, upkeep, repair and security of computer equipment 

and networks. In addition, the Maintenance Office directs the selection and supervision of any external 

maintenance providers. 

IT Services: IT and Communication Services are provided jointly by the CIDEIM Administrative Unit and ICESI 

University. The IT & Communications Officer at CIDEIM coordinates all institutional videoconferences using 

the ZOOM teleconferencing software, and designs and conducts training in these and other IT educational and 

communication tools. In addition, this officer supervises the IT troubleshooting services by ICESI to CIDEIM 

personnel. 

ESEARCH PROMOTION AND DEVELOPMENT UNIT

he following support processes are managed by this unit. 

Project Support in the pre-award phase: The unit maintains all institutional registrations (such as DUNS, 

SAMS, eRA Commons and others) required for application to national and international funding agencies up 

to date, assists investigators in identifying and understanding funding opportunities and in complying with the 

funding agency instructions and requirements for applications, and manages the internal review for obtaining 

institutional approval and authorization to submit the application.

E-Learning: The unit provides professional accompaniment at CIDEIM in the integration, management and 

use of information technology in courses in relation with research projects, research capacity strengthening 

projects and institutional training programs. CIDEIM has developed institutional capacity to interface with 

content and curriculum designers to create and use virtual learning methodologies. CIDEIM IT staff deliver 

web- based courses through the ZOOM platform to the National Postgraduate Training Network. IT staff and 

the course coordinators in each of the institutions participating in the National Postgraduate Training Network 

have received training to assure that each institution has the capacity to troubleshoot and manage the 

videoconference sessions. CIDEIM IT personnel have experience in the use of Moodle and have employed 

this open-access platform to create templates for post graduate Web-Based courses, the blended learning 

course on Statistics Applied to Biomedical Research and short courses on Good Clinical Practices and Effective 

Project Planning and Evaluation in Health Research offered each year by CIDEIM. The CIDEIM Learning 

Management System (Moodle) allows for storage of course materials, videoconference recordings, forums and 

quizzes, as well as interaction among course participants from the different cities, between course sessions.

Training and Career Development in Science, Technology and Innovation (STI): Research training is a 

core activity of CIDEIM and is conducted within the framework of ongoing research and technical services. 

Research capacity is built through a diverse portfolio of training modalities, which support and extend 

undergraduate and postgraduate programs in health sciences available at national and regional universities. 

The unit oversees all internal and external training activities and manages a database to track all applicants 

and participants. Descriptions of training opportunities and course offerings are posted on the CIDEIM website 

and announcements are distributed to target institutions via email. CIDEIM welcomes national and international 

trainees to participate in the institution’s ongoing research and training programs. The training program is 

directed to students interested in scientific and technological innovation through research, and includes the 

following training modalities: 1) Supervised undergraduate, master’s and doctoral thesis research; 2) Young 

R

T

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 10
Investigator mentored research training for outstanding recent graduates; 3) Social service and internship 

training for medical graduates and health professionals; 4) Health sciences post-graduate courses offered inperson and through web-based modalities.

Research Capacity Strengthening: The unit applies, manages and conducts institutional research capacity 

strengthening projects/programs funded by national and international funding agencies. One of these is that 

of CIDEIM as Latin American and Caribbean Regional Training Center supported by the he Special 

Programme for Research and Training in Tropical Diseases (TDR) 

https://www.who.int/tdr/news/2015/regional_training_centers/en/ .

 

Communications: The unit provides professional support for the development and implementation of 

communication strategies to reach different audiences at the project and institutional levels with the effective 

use of available resources.

FACILITIES 

CIDEIM headquarters have been strategically designed based on the specification for the research, training and 

service mission of CIDEIM. Interior space is 2,300 m2. A unique feature of the center is that it is essentially selfcontained, comprising outpatient clinical facilities and full time medical staff for routine clinical diagnosis and 

management of the diseases under investigation, research laboratories, insectary, and administrative and 

technical support infrastructure and personnel. The outpatient clinic, pharmacy, research laboratories and core 

facilities . The library, documentation and communications center, biostatistics and 

epidemiology laboratory, clinical archive, investigator cubicles, computer systems, administrative offices and 

meeting rooms . 

A. Laboratories: 

a) Biochemistry and Molecular Biology: This research Unit has the infrastructure to conduct proteomic and 

functional genomics research. This laboratory is equipped with multiple thermocyclers, hybridization ovens, 

heating blocks, DAN/RNA concentrator, refrigerators and freezers, extraction hood, electroporator, 

analytical balance, water bath, vertical and horizontal electrophoresis chambers and microcentrifuges, 

which support the performance of nucleic acid and protein extraction, cloning, PCR, real time qPCR, 

Southern/Northern/Western hybridization techniques, SDS and 2D-SDS-PAGE, constructions of RNA 

libraries for RNAseq analyses and gene knockdown using short hairpin interference RNA. 

b) Immunology and Cell Biology: This research Unit has the capability to evaluate the immune response 

at the local, systemic and cellular level using technologies such as cytometric analysis, phenotypic and 

functional markers and products of leukocytes, real time PCR of gene products and transcription factors, 

and ex vivo analysis of cells of the inflammatory and immune response. Primary peripheral blood 

monocytes, macrophages, neutrophils, eosinophil, NK, fibroblast and dendritic cells can also be cultured 

and functional analysis conducted. This laboratory is equipped with three Thermo Scientific refrigerated 

tabletop centrifuges, two inverted microscopes one provided with a video cam and three light microscopes, 

two ELISA plate readers and printers, water baths, refrigerators, minimacs and quadromacs magnetic cell 

separator equipment, dedicated computer with Flowjo software for cytometric analyses. The laboratory 

has a dedicated and independent space for cell culture equipped with culture flow hoods with five 

simultaneous working spaces, and incubators coupled to CO2 influx system. An independent dark room 

has been adapted exclusively for immunofluorescence microscopy and image analysis with Nikon imaging 

software. 

c) Biostatistics and Epidemiology: This unit collaborates with the research teams in the planning, execution 

and analysis of research studies, with the overall aim of ensuring valid traceable data and quantitative 

analysis. Activities include: sample size calculations, sampling methods, statistical analysis, preparation of 

reports and publications. This unit has responsibility for data management which incororates development 

of databases and custom data entry screens, maintenance of data quality by double data entry and 

interactive checks, and provision of data in the form needed for reports and analysis. Available software 

includes STATA, Microsoft Office, Epi Info, R and SQLServer. 

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 11
d) Microbiology: This Unit has the infrastructure to type and phenotypically characterize clinically-relevant 

microbial pathogens (bacteria and parasites), using conventional culture methods and PCR-based 

techniques. Also the capacity to do molecular epidemiology using pulse field electrophoresis (PFGE), PCR 

and MLST typing of bacterial genomes. This information is used to diagnose and monitor patterns of 

nosocomial infections in hospital settings. Host-pathogen interactions and mechanistic studies of bacterial 

infections in the context of drug resistance and persistence is another focus of the Unit. The Microbiology 

Unit also includes the infrastructure required for working with Biosafety Level III pathogens such as 

M.tuberculosis i.e. negative-pressure room and biosafety hood. 

e) Vector Biology and Control: The Unit ́s physical infrastructure includes a general research area and 

insect colonies, consisting of three spaces for individual colonization of vector species, each of these with 

independent areas for experimental infection. All areas are equipped with physical barriers avoiding insect 

escape between and outside of the colonies (BSL 2+). This unit is equipped with all elements necessary 

for entomological research (insect capture traps, microscopes, stereos, etc.), as well as equipment for 

capture of small mammalian species (National and Sherman traps), microphotography, microinjection, and 

dissection, molecular assays and insect cellular cultures. The unit has the capacity to use computational 

tools for statistical and geospatial analyzes in order to identify risk variables that allow the design of 

prevention and control strategies for vector transmitted diseases. 

B. Core Facilities: 

a) Culture Facilities: Four laboratories are dedicated to aseptic culture of cells and microbial pathogens. 

These are equipped with biosecurity level II and III facilities for working with high risk microorganisms such 

as multidrug resistant Mycobacterium tuberculosis, dengue virus, and HIV positive clinical samples as well 

as human cell and parasite cultures. Within these controlled- access areas the following equipment is 

available: standard, CO2, and low temperature (25°C) incubators, light microscopes, inverted 

microscopes, and laminar flow bio-safety hoods with gas outlets. 

b) PCR -qPCR facility: This facility is equipped with 5 conventional PCR thermocyclers with capacity to do 

temperature gradients, 96 well plate runs and independent block runs, among others. In addition the facility 

is equipped with a Real Time thermocycler (CFX96BioRad) with analytical software for Gene expression 

and Precision Melt Analyses, a Nanodrop spectroscopy and a BioAnalyzer-Agilent 2100 for quantifying 

micro quantities of nucleic acids and proteins and for verifying quality. Designated and segregated areas 

have been established for the conduct of the different steps of molecular amplification, in order to avoid 

carryover and contamination of samples. An external sample analysis and imaging area has been 

established equipped with a GelDoc EX(BioRad) imaging system. 

c) Flow Cytometry facility: This facility is equipped with a Becton Dickinson Accuri C6 Flow Cytometer and 

FlowJo, Summit and other specialized analysis software tools. This facility is temperature-controlled, 

guarantying the ideal functioning of the equipment. 

d) Cold Room: This facility has been designated to contain ultrafreezing equipment including -80°C, -45°C 

and -20°C freezers. This area is temperature-controlled and supervised with a central temperature control 

and monitoring system for all the equipment in the facility. 

e) BioBank: CIDEIM’s biobank has currently more than 3,000 strains of Leishmania spp., 260 Trypanosoma

spp., 630 isolates of Plasmodium falciparum, 4,600 Mycobacterium spp. isolates and > 3,600 of Gram(-) 

bacteria, with their susceptibility/resistance profiles characterized. In addition, DNA and plasma samples 

are preserved from patients with tuberculosis, malaria, syphilis and leishmaniasis, and skin biopsies from 

patients with secondary syphilis and leishmaniasis. The biobank is equipped with 5 Liquid Nitrogen Storage 

Vessels with a capacity of 4800 vials each and 2 ultrafreeezer (-80°C) with a capacity of 45000 vials. 

Management of the biological material stored in the biobank is supported by the Biobanco CIDEIM® 

software, according to ethical and legal guidelines. 

f) Autoclaving Facility: Materials are washed, sterilized and packaged and disposed in this area. Equipment 

includes two autoclaves, balances, glassware, washing and drying facilities and general use for reagents 

and supplies required for solution and culture media preparation. 

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 12
C. Clinical Infrastructure: 

a) CIDEIM-Cali: Members of the Clinical Unit team include the Unit Leader and Coordinator, one Clinical 

Research Assistant, two Clinical Research Fellows, a laboratory specialist and a clinical technician. The 

assistant, research fellows and clinical specialists participate heavily in the design of necessary research 

documents (CRFs, SOPs, informed consent forms, etc.), manage patient records and other clinical 

research documentation. They guarantee ethical conduct, enrollment, treatment and follow-up activities. 

The clinical laboratory specialist carries out parasitological diagnosis of study participants, and ensures 

that samples are collected, processed, stored and shipped according to GCLP guidelines. 

Clinical facilities include two consulting offices, a room equipped for basic diagnostic procedures, a 

separate area for phlebotomy, an independent patient waiting room, two offices and a reception room. The 

diagnostic laboratory is equipped to process samples and perform diagnostic tests for syphilis, HIV and 

leishmaniasis, and isolation and identification of different species of Leishmania. The diagnostic unit has 

the capability of training and advising other laboratories in the use of different methods for the diagnosis 

of Leishmaniasis, syphilis and malaria, and has been contracted by the Pan-American Health Organization 

to conduct training in diagnosis of leishmaniasis in the reference laboratories of the countries of the 

Americas reporting the most cases. 

Importantly, the Clinical Unit has the support of infectious disease specialists from the Fundación Valle del 

Lili, a level 4 hospital, and a dermatology specialist (Dr. Adriana Cruz), who provide support for the clinical 

management of complicated or unusual cases. 

b) CIDEIM-Tumaco: Considering that the large proportion of current CIDEIM study participants come from 

the South Pacific area of Colombia, the Clinical Research Unit includes a clinical and laboratory facility in 

Tumaco-Nariño, a recognized endemic area for dermal leishmaniasis, malaria, dengue and other vector 

borne diseases, where CIDEIM has conducted clinical research activities since 1980. Members of the 

CIDEIM-Tumaco clinical team include a medical coordinator and two laboratory specialists. This clinical 

facility is fully equipped to provide primary care (level 1) attention, outfitted with all the necessary equipment 

and supplies to perform diagnostic procedures (i.e. direct smears, culture of lesion aspirates, skin biopsies) 

and research sample collection. The facility has an independent power generator to assure back up of 

equipment during power outage. Electronic medical records and e-CRFs have been designed according 

to GCP standards and national regulations, and implemented to allow timely availability of data and 

improve security. Biological samples are regularly shipped for storage and processing in CIDEIM-Cali. 

Regular supervisory visits are made by CIDEIM-Cali clinical and laboratory staff for monitoring and 

improvement of the operation in accordance with good practices and public health licensing to operate. 

In addition to the outpatient clinical facilities available in CIDEIM, tertiary level hospital facilities for research 

requiring hospitalization and clinical support are available at the nearby Fundacion Valle de Lili Clinic and 

COLSANITAS Clinica Sebastián de Belacazar in Cali. A Level 2 clinical care center is available at study 

sites in the Regional Hospital San Andres in Tumaco. 

D. Additional access to research technologies and infrastructure through national interinstitutional 

collaborations 

Through our network of collaborators and partnering institutions, CIDEIM has broaden its access to current 

technologies and infrastructure that support the development of biomedical research. This “technology 

network” creates an important standpoint for joint research, promoting collaboration and non-redundant 

acquisition of large scale state-of-the-art infrastructure that supports high quality research. Among these are:

Confocal Microscopy: CIDEIM researchers have access to an imaging facility equipped with a Zeiss 

LSM 700 microscope and image analysis software (including capacities for 3D reconstruction colocalization, marker quantitation, among others) at Universidad del Valle. User training sessions and staff 

are available for new users. 

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 13
Luminex: Universidad del Valle has recently acquired a Luminex system, ideal for the evaluation of 

complex samples and multiparamenter analysis. Through our continuing collaboration, CIDEIM research 

staff has access to this technology and applications. 

Experimental Animal Breeding Facility: Through our partnership with Universidad ICESI we have 

access to the Animal Facility which has capacity to house 600 small laboratory rodents (Mus musculus: 

Swiss Albino; Mesocricetus auratus, inbred Chester Beaty, MHA and outbred hamsters; Merionis 

unguiculatus; Rattus sp: wistar rats), 48 White New Zealand Rabbits, and 5 pigs or sheep in four separate 

temperature controlled rooms. A laboratory for surgical and sampling procedures, with a level II laminar 

flow hood, electronic balance, light microscope, and CO2 apparatus for euthanasia, as well as room for 

cage washing and a storeroom are located within the vivarium. 

INFORMATION AND COMMUNICATION 

Library and Documentation Center: In support of the different academic, scientific and research programs, 

the CIDEIM library offers a computerized bibliographic information system. In addition, the library provides 

guidance to users on bibliographic searches, bibliographic reviews, lending of journals and books, and electronic 

bibliographic consulting. An online database has been developed by the CIDEIM library: SCCOT (general 

collection books, final reports, CIDEIM publications). Additionally, through the partnership with ICESI University, 

CIDEIM has access to the university library, which is part of a larger Services and Resources Unit. 

Computer Resources: The 180 node network operates under a star-format and is controlled by a Windows 

server 2016 Standard controlling computer access to internet and internal ftp. The network and computer 

configuration allow sharing of resources such as desks and printers located at different sites of the institution, 

thereby facilitating remote access to information located at each site. These resources are protected with 

Ninety computers are currently available to users of CIDEIM ICT service. These are provided with Microsoft 

Office software, browsers and some with applications for data analysis. Six printers (1 dot matrix, 5 laser) and 

one photocopier are available for use according to printing needs. Full time internet connection is achieved 

through a dedicated internet service. All computers are connected to a domain server. Importantly, CIDEIM has 

a Volume Licensing with Microsoft that facilitates use of software including Microsoft Office 365 by a large 

number of users at a modest cost. 

Document Management: CIDEIM has implemented Sharepoint online, this tool is a collaborative plataform web 

based that allows sharing news, SOPs and procedures registered in the Quality System Management, 

communication of internal orders and requirements to the Administrative Unit and log in to Institutional 

Databases. In addition, CIDEIM has implemented OneDrive for all users, this tool is a file hosting service that 

allows users to create, edit, share, and sync files in their computers and to access them from a web browser or 

mobile device. This tool strength the collaborative work. 

Videoconferencing Resources: Videoconferencing facilities are available on site within CIDEIM, with three 

appropriately furnished conference rooms. The larger conference room is equipped with video projector, an audio 

system (amplifier, speakers and microphones), and a dedicated desktop computer with Microsoft software. The 

other two conference rooms, meant to be used for videoconferences with small groups of local participants, are 

equipped with 42” Sharp LCD flat screen television with appropriate video and audio connections to laptop. 

Transmission of web-based courses, connecting international collaborators and the members of the Colombian 

Postgraduate Training Network, is achieved through ZOOM platform. CIDEIM employs a dedicated laptop for 

videoconferencing needs, including archiving session recordings. In addition, the recordings are loaded in the 

YouTube private channel of CIDEIM. In addition to its internal resources, CIDEIM has access to the conferencing 

and other facilities of ICESI University. 

Contact PD/PI: Jaramillo Zuluaga, Andres Facilities & Other Resources Page 14
OMB Number: 4040-0001

Expiration Date: 10/31/2019

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED Senior/Key Person Profile (Expanded)

PROFILE - Project Director/Principal Investigator

Prefix:  First Name*: Andres Middle Name  Last Name*: Jaramillo Zuluaga Suffix: 

Position/Title*: Coordinator Research Promotion and Developmen

Organization Name*: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Department:

Division:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

Zip / Postal Code*:

Phone Number*: Fax Number: 

E-Mail*: 

Credential, e.g., agency login: 

Project Role*:  PD/PI Other Project Role Category: 

Degree Type:  MBA Degree Year:  2014

Attach Biographical Sketch*:             File Name: Jaramillo_Andres_Biosketch.pdf

Attach Current & Pending Support:   File Name:

Contact PD/PI: Jaramillo Zuluaga, Andres Page 15
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

PROFILE - Senior/Key Person

Prefix:  First Name*: Cindy Middle Name Vanessa Last Name*: Montero Suffix: 

Position/Title*: Administrative Coordinator

Organization Name*: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Department:

Division:

Street1*:

Street2:

City*: Cali

County:

State*:

Province:

Country*: COL: COLOMBIA

Zip / Postal Code*:

Phone Number*:  Fax Number: 

E-Mail*: 

Credential, e.g., agency login: 

Project Role*:  Co-Investigator Other Project Role Category: 

Degree Type:  Degree Year: 

Attach Biographical Sketch*:             File Name: Montero_Vanessa_Biosketch.pdf

Attach Current & Pending Support:   File Name:

Contact PD/PI: Jaramillo Zuluaga, Andres Page 16
OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Jaramillo Zuluaga, Andres 

eRA COMMONS USER NAME (credential, e.g., agency login): 

POSITION TITLE: Coordinator Research Promotion and Development Unit 

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, 

include postdoctoral training and residency training if applicable. Add/delete rows as necessary.) 

INSTITUTION AND LOCATION DEGREE END FIELD OF STUDY 

(if applicable) DATE 

MM/YYYY 

Universidad Icesi, Cali, Valle del BBA 02/2005 Management 

Cauca 

Universidad Icesi, Cali, Valle del MBA 08/2014 Strategic Management 

Cauca 

Colombia Stock Exchange, Cali Other 07/2005 Diploma - Operation of Colombia Stock 

training Exchange 

Universidad Icesi, Cali Other 07/2008 Diploma - Project Management 

training 

A. Personal Statement

My undergraduate and graduate training in Business Administration and Management, subsequent research 

management experience as Assistant to the Scientific Direction, Coordinator of the Research and Training 

portfolio and currently, as Coordinator of the Research Promotion and Development Unit have allowed me to

understand and to bridge the research program and administrative requirements of the Centro Internacional de

Entrenamiento e Investigaciones Medicas (CIDEIM). In this capacity, I serve as Administrative Official with 

responsibility for grants administration. These roles and responsibilities have given me the opportunity to

interact at national and international levels with researchers and trainees, university faculty and administrators, 

and funding agencies. Within CIDEIM, I engage and support scientific and administrative personnel in the 

coordination of pre and post award activities, update grants management policies and procedures, and ensure 

policy implementation and compliance. Additionally, together with the Research Promotion and Development 

Unit team members I provide administrative support for the development of proposals and administrative 

oversight of active projects. I also conduct in-house and external, including international training, in Effective 

Project Planning and Evaluation in Health Research. 

B. Positions and Honors

Positions and Employment

2004 - 2005 Financial Administrative Assistant, Fiduciaria FES, Cali 

2005 - 2006 Administrative and Financial Consulting, “Estudio Abierto” Architects, Cali 

2007 - 2011 Assistant to the Scientific Direction, Centro Internacional de Entrenamiento e Investigaciones

Médicas (CIDEIM), Cali 

2011 – 2018 Coordinator, Research & Training Portfolio, Centro Internacional de Entrenamiento e 

Investigaciones Médicas (CIDEIM), Cali 

2018- Coordinator of Research Promotion and Development Unit, Centro Internacional de

Entrenamiento e Investigaciones Médicas (CIDEIM), Cali 

Other Experience and Professional Memberships

2009 - Secretary of the Board of Directors, Centro Internacional de Entrenamiento e Investigaciones 

Médicas (CIDEIM) 

2009 - 2009 WHO Temporary Adviser. Meeting on Harmonization of Short Training Courses on GCPContact PD/PI: Jaramillo Zuluaga, Andres Biosketches Page 17
GCLP/Basic research/Bioethics/PPM/Social Sciences/Data management/Product Research 

and Development- Thammasat University, Bangkok Thailand, 9-17 February 2009, Special 

Programme for Research and Training in Tropical Diseases (TDR), World Health Organization. 

2011 - 2011 Participation in the NIH, Grants Policy and Management Training, Panama City, Panama, 

November 30 - December 2, 2011., National Institute of Allergy and Infectious Diseases 

(NIAID), 

2013 - 2013 Invited facilitator for EPPE (Effective Project Planning and Evaluation in Biomedical Research) 

Skill Building training for Erasmus Mundus Scholars for the tropEd Masters of Science 

Programme in International Health. Bordeaux Segalen University, Bordeaux, France, 4-14

March 2013., Erasmus Mundus Scholars for the tropEd Masters of Science Programme in

International Health 

2013 - 2013 Attendance of the annual meeting of the Society of Research Administration (SRA) and precongress workshop “Introduction to Research Administration and Management”, New Orleans, 

United States, October 27-30, 2013, Society of Research Administration (SRA) 

2013 - 2013 Invited facilitator for Implementation Research (IR) Training Workshop in Accra, Ghana from

25-29 November, 2013, hosted by the Dodowa Health Research Centre, Special Programme 

for Research and Training in Tropical Diseases (TDR), World Health Organization. 

2014 - 2014 WHO Temporary Advisor. Review committee for the selection of a Regional Training Center 

supported by TDR in the WHO-AFRO region, Geneva, Switzerland, 22-24 September 2014., 

Special Programme for Research and Training in Tropical Diseases (TDR), World Health 

Organization 

2015 - 2015 WHO Temporary Advisor. Review committee for the selection of a Regional Training Center 

supported by TDR in the WHO-EMRO region, Geneva, Switzerland, 5-6 February 2015., 

Special Programme for Research and Training in Tropical Diseases (TDR), World Health 

Organization. 

2015 - 2015 Participation in TDR Consultation on promoting implementation / operational research in

countries receiving Global Fund grants. Domaine de Penthes, Geneva, Switzerland, 9-10

December 2015., Special Programme for Research and Training in Tropical Diseases (TDR), 

World Health Organization. 

C. Contribution to Science

1. During the past ten years I have participated in diverse strategies to build research and research training 

capacity in CIDEIM and its collaborating institutions. Almost immediately after I joined CIDEIM I was 

trained in the TDR short course “Effective Project Planning and Evaluation in Biomedical Research 

(EPPE)” in February 2007. Afterwards, I was trained as a trainer in May 2007. Since then, I have led seven 

Skill-Building and two Train-The-Trainer courses, disseminating the TDR EPPE methodology in Quito, 

Ecuador; Bordeaux, France; Rio de Janeiro, Brazil; Bogota and Cali, Colombia. Additionally, I participated 

as a facilitator for the Implementation Research course conducted in Accra, Ghana in 2013. I have worked 

to assure the permanent institutionalization of these project planning and evaluation tools and other 

research skill building courses within CIDEIM. I have promoted and participated in the organization of webbased courses and seminars offered through the research training program that CIDEIM and Yale 

University have collaboratively developed with national and regional doctoral programs in biomedical 

science through the Global Infectious Disease (GID) Research Training program supported by the USNIH 

Fogarty International Center. Currently, I coordinate the dissemination of training by CIDEIM as the Latin 

American Regional Training Centre supported by the WHO TDR programme in collaboration with the WHO 

Regional Office for the Americas (WHO-AMRO). 

a) Alger J; Gómez L; Jaramillo A; Saravia NG; Cuervo LG; Halpaap B. 2010. Reunión de la Red InterRegional de Centros de Referencia para capacitación en cursos de planeación y evaluación efectivas 

de proyectos de investigación para la salud; Cali; Colombia. Rev Med Hondur. 78(2):97-100

b) Tulloch-Reid MK; Saravia NG; Dennis Verano RJ; Jaramillo A; Cuervo LG; Walker SP; Salicrup LA. 

2018. Strengthening institutional capacity for equitable health research: lessons from Latin America and

the Caribbean. BMJ. 362: k2456. doi: 10.1136/bmj.k2456. PMID: 30012634. PMCID: PMC6046649 

Contact PD/PI: Jaramillo Zuluaga, Andres Biosketches Page 18
c) Gomez L; Jaramillo A; Halpaap B; Launois P; Cuervo LG; Saravia NG. 2019. Building research 

capacity through “Planning for Success”. August 1, 2019. Plos Negl Trop Dis. 13(8): e0007426.

https://doi.org/10.1371/journal.pntd.0007426 

D. Additional Information: Research Support and/or Scholastic Performance

Ongoing Research Support

 11/2013-12/2019 

 

Role: Project manager 

D43 TW006589 (Christian Tschudi PI/PD, Nancy Saravia Foreign PI/PD) 01/2007-12/2019

Fogarty/NIH 

Translational Research Training on Leishmaniasis & Emerging Infectious Diseases 

Fogarty International Center Global Infectious Disease Training Program to increase research capacity to

identify, evaluate and implement strategies to interrupt the transmission and pathogenesis of leishmaniasis and

other vector-borne and emerging infectious diseases in Colombia and the Latin American Region. 

Role: Project manager 

1U19AI129910 (Nancy Gore Saravia PD/PI) 04/2017-03/2022 

NIH/NIAID 

Optimizing Surveillance and Treatment for Control of Cutaneous Leishmaniasis 

This program undertakes three interrelated research projects that focus on improving control of CL through the 

use of different approaches that target P-1) populations at risk requiring access to diagnosis and treatment, P2) parasites having a wide range of variation in drug susceptibility, and P-3) innate host defense mechanisms 

that can impair or promote therapeutic response. 

Role: Admin Core - Program coordinator 

Contact PD/PI: Jaramillo Zuluaga, Andres Biosketches Page 19
OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES. 

NAME: Montero, Vanessa 

eRA COMMONS USER NAME (credential, e.g., agency login): 

POSITION TITLE: Administrative Coordinator 

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such 

as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as

necessary.) 

INSTITUTION AND DEGREE END FIELD OF STUDY 

LOCATION (if DATE 

applicable) MM/YYYY 

Universidad Icesi, Cali M.ENG 02/2019 Industrial Engineering (Thesis: 

Knowledge management in human 

resource processes in a research 

center) 

Universidad del Valle, Cali B.ENG 04/2012 Industrial Engineering 

ICONTEC, Cali Other training 12/2012 Diploma in Integrated Management 

Systems HSEQ

CIDEIM supported by WHO- Other training 10/2018 Train-The-Trainer Good Clinical 

TDR, Cali Laboratory Practice (GCLP) 

CIDEIM Developed with the Other training 03/2015 Effective Planning and Evaluation in

support of UNICEF / UNDP / Health Research Projects 

World Bank / WHO, Cali 

A. Personal Statement

My educational background in industrial engineering and my work experience have been

developed in relation with performance analysis, quality assurance, and human resource and

administrative management. Early in my career I worked at Universidad del Valle, a large public 

university considered to be the principal institution of higher education in southwestern Colombia. 

There, in the Office of Institutional Planning I supported quality assurance and audit processes of

various administrative units of the institution. I also had the opportunity to work in the Human 

Resources Division providing support to the structuring of procedures, action plans, programs and

tools for measuring the organizational climate. During this experience at the Universidad del Valle 

I had the opportunity to learn about its administrative, training, research and personnel benefits 

processes. 

As Administrative Coordinator of the Internacional de Entrenamiento e Investigaciones Médicas 

(CIDEIM), I am responsible for the design and support of a wide range of organizational processes 

including the development and implementation of policies and procedures, as well as compliance 

with institutional and government guidelines and regulations including the recent re-certification of

Contact PD/PI: Jaramillo Zuluaga, Andres Biosketches Page 20
CIDEIM by our food and drug agency INVIMA, in Good Clinical Practices. Since 2016 I support 

the area of Human Resource Management and have worked together with the Direction of the 

CIDEIM on policies in relation with organizational structure, and compensation and benefits 

received by institutional personnel. In accordance with my role in quality assurance of all 

administrative processes, I have had the opportunity to participate in training courses on Good 

Laboratory Practices, Good Clinical Practice, Effective Project Planning and Evaluation, and in

the Train-the-Trainer course Good Clinical Laboratory Practice (GCLP), all of which has allowed 

me to understand and interact with the laboratory area and gain an integral view of the research 

process. 

B. Positions and Honors

Positions and Employment

2015 - Administrative Coordinator, Centro Internacional de Entrenamiento e 

Investigaciones Médicas - CIDEIM, Cali 

Mar- May 2014 General Coordinator, Politécnico Empresarial Colombiano, Cali 

2012 - 2014 Professional Contractor, Quality and Improvement Area, Universidad del Valle, 

Cali 

2012 - 2012 Professional Contractor Human Management, Universidad del Valle, Cali 

2010 - 2012 Facilitator analyst, Corporación para el Desarrollo de la Ecología, Calidad y 

Tecnología, Cali 

Other Experience and Professional Memberships

2011 - 2013 Internal Quality Auditor under the NTCGP1000 Standard, Universidad del Valle 

Oct – Dic 2010 Professional Consulting, Project for the Implementation of a Public 

Management Indicators System for the city of Cali 

Honors

2008 - 2010 Administrative Fellow of the Quality and Improvement Area, Universidad del

Valle 

C. Contribution to Science

At the Universidad del Valle and at the Centro Internacional de Entrenamiento e Investigaciones 

Médicas (CIDEIM), I have supported the research and training missions of these institutions in the 

structuring of policies, procedures and actions that facilitate, sustain and improve the capacity for 

the development and dissemination of knowledge. Some of the institutional documents in which I 

have participated in developing and writing are the following: 

Universidad de Antioquia, Centro Internacional de Entrenamiento e Investigaciones Médicas –

CIDEIM, Cooperative Agreement between Universidad de Antioquia y CIDEIM, 2019. 

Centro Internacional de Entrenamiento e Investigaciones Médicas – CIDEIM, Annual Report 

2018. 

Universidad Icesi, Centro Internacional de Entrenamiento e Investigaciones Médicas – CIDEIM, 

Interinstitutional Framework Agreement between Universidad Icesi y CIDEIM, 2018.

Contact PD/PI: Jaramillo Zuluaga, Andres Biosketches Page 21
Framework Agreement for Academic and Scientific Cooperation between Universidad Libre 

Sectional Cali (Colombia) y la Corporación Centro Internacional de Entrenamiento e 

Investigaciones Médicas CIDEIM, 2018.

Centro Internacional de Entrenamiento e Investigaciones Médicas – CIDEIM, MAN01015 

Manual for Administration and Control of Fixed Assets, Version 01, 2018.

Centro Internacional de Entrenamiento e Investigaciones Médicas – CIDEIM, MAN01005 

Manual of Responsibilities and Functions in Research Projects, Version 03, 2017. 

Centro Internacional de Entrenamiento e Investigaciones Médicas – CIDEIM, MAN01016 

Conflict of Interest and Commitment Policy, Version 01, 2018

Centro Internacional de Entrenamiento e Investigaciones Médicas – CIDEIM, SOP01007 Control 

of documents, Version 11, 2018. 

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Technical Report: User Satisfaction, 2013. 

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Executive and Technical Report: Organizational Climate at the Universidad del

Valle, 2013. 

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Institutional Report: Analysis of results and data of Internal Quality Audits 2012: 

Fifth and Sixth Cycle of Audits. 

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Institutional Report: Consolidation and analysis of results of process performance 

indicators. 2012

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Institutional Report on the status of corrective, preventive and improvement 

actions by process. 2012

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Internal quality audit program and prioritization factors: Eighth cycle of audits. 

2014.

Universidad del Valle, Office of Institutional Planning: Area of Quality Assurance and 

Improvement. Executive and Technical Report: Diagnosis of the implementation of

Comprehensive Quality Management System of the Universidad del Valle, according to the 

subsystems, components and elements of the standard Internal Control Model. 2013

Support and advice to those responsible for processes of the Universidad del Valle in the 

consolidation and updating of policies, procedures and formats for: Institutional Planning, 

Institutional Communication, Management of Goods and Services, Human Resource 

Management, Management of Technological Resources, Management of Improvement, Quality 

Management, Control Management, Financial Management, Training and Research and 

Knowledge Generation. August 2010 to February 2014.

Contact PD/PI: Jaramillo Zuluaga, Andres Biosketches Page 22
OMB Number: 4040-0001

Expiration Date: 10/31/2019

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date: 2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED BUDGET - SECTION A & B, Budget Period  1

ORGANIZATIONAL DUNS*:   

Budget Type*: ● Project ❍ Subaward/Consortium

Enter name of Organization: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Start Date*: 05-01-2020 End Date*: 04-30-2021 Budget Period: 1

A. Senior/Key Person

# Prefix First Name* Middle Last Name* Suffix Project Role* Base Calendar Academic Summer Requested Fringe Funds Requested ($)*

Name Salary ($) Months Months Months Salary ($)* Benefits ($)*

1 . Andres Jaramillo Zuluaga PD/PI 3.0

2 . Cindy Vanessa Montero Co-Investigator 3.0

Total Funds Requested for all Senior Key Persons in the attached file

Additional Senior Key Persons: File Name: Total Senior/Key Person

Mime Type:

B. Other Personnel

Number of Project Role* Calendar Months Academic Months Summer Months Requested Salary ($)* Fringe Benefits* Funds Requested ($)*

Personnel*

Post Doctoral Associates

Graduate Students

Undergraduate Students

Secretarial/Clerical

1 Financial Officer 3.0

1 Total Number Other Personnel Total Other Personnel

Total Salary, Wages and Fringe Benefits (A+B)

RESEARCH & RELATED Budget {A-B} (Funds Requested)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 23
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED BUDGET - SECTION C, D, & E, Budget Period 1

ORGANIZATIONAL DUNS*: 

Budget Type*: ● Project ❍ Subaward/Consortium

Organization: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Start Date*: 05-01-2020 End Date*: 04-30-2021 Budget Period: 1

C. Equipment Description

List items and dollar amount for each item exceeding $5,000

Equipment Item Funds Requested ($)*

Total funds requested for all equipment listed in the attached file

Total Equipment 0.00

Additional Equipment: File Name:

Mime Type:

D. Travel Funds Requested ($)*

1. Domestic Travel Costs ( Incl. Canada, Mexico, and U.S. Possessions)

2. Foreign Travel Costs

Total Travel Cost

E. Participant/Trainee Support Costs Funds Requested ($)*

1. Tuition/Fees/Health Insurance

2. Stipends

3. Travel

4. Subsistence

5. Other: 

 Number of Participants/Trainees Total Participant Trainee Support Costs 0.00

RESEARCH & RELATED Budget {C-E} (Funds Requested)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 24
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED BUDGET - SECTIONS F-K, Budget Period 1

ORGANIZATIONAL DUNS*: 

Budget Type*: ● Project ❍ Subaward/Consortium

Organization: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Start Date*: 05-01-2020 End Date*: 04-30-2021 Budget Period: 1

F. Other Direct Costs Funds Requested ($)*

1. Materials and Supplies

2. Publication Costs

3. Consultant Services

4. ADP/Computer Services

5. Subawards/Consortium/Contractual Costs

6. Equipment or Facility Rental/User Fees

7. Alterations and Renovations

8 . Other: Materials translations in Spanish

9 . Other: Development of Online components for the grants management training program

10 . Other: Distance learning - webinar training or videoconferencing

Total Other Direct Costs

G. Direct Costs Funds Requested ($)*

Total Direct Costs (A thru F)

H. Indirect Costs

Indirect Cost Type Indirect Cost Rate (%) Indirect Cost Base ($) Funds Requested ($)*

1 . MTDC 8.0

Total Indirect Costs

Cognizant Federal Agency

(Agency Name, POC Name, and POC Phone Number)

I. Total Direct and Indirect Costs Funds Requested ($)*

Total Direct and Indirect Institutional Costs (G + H)

J. Fee Funds Requested ($)*

K. Total Costs and Fee Funds Requested ($)*

L. Budget Justification* File Name: Budget_justification.pdf Mime Type: application/pdf

(Only attach one file.)

RESEARCH & RELATED Budget {F-K} (Funds Requested)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 25
OMB Number: 4040-0001

Expiration Date: 10/31/2019

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date: 2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED BUDGET - SECTION A & B, Budget Period  2

ORGANIZATIONAL DUNS*:   

Budget Type*: ● Project ❍ Subaward/Consortium

Enter name of Organization: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Start Date*: 05-01-2021 End Date*: 10-31-2021 Budget Period: 2

A. Senior/Key Person

# Prefix First Name* Middle Last Name* Suffix Project Role* Base Calendar Academic Summer Requested Fringe Funds Requested ($)*

Name Salary ($) Months Months Months Salary ($)* Benefits ($)*

1 . Andres Jaramillo Zuluaga PD/PI 3.0

2 . Cindy Vanessa Montero Co-Investigator 3.0

Total Funds Requested for all Senior Key Persons in the attached file

Additional Senior Key Persons: File Name: Total Senior/Key Person

Mime Type:

B. Other Personnel

Number of Project Role* Calendar Months Academic Months Summer Months Requested Salary ($)* Fringe Benefits* Funds Requested ($)*

Personnel*

Post Doctoral Associates

Graduate Students

Undergraduate Students

Secretarial/Clerical

1 Financial Officer 3.0

1 Total Number Other Personnel Total Other Personnel

Total Salary, Wages and Fringe Benefits (A+B)

RESEARCH & RELATED Budget {A-B} (Funds Requested)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 26
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED BUDGET - SECTION C, D, & E, Budget Period 2

ORGANIZATIONAL DUNS*: 

Budget Type*: ● Project ❍ Subaward/Consortium

Organization: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Start Date*: 05-01-2021 End Date*: 10-31-2021 Budget Period: 2

C. Equipment Description

List items and dollar amount for each item exceeding $5,000

Equipment Item Funds Requested ($)*

Total funds requested for all equipment listed in the attached file

Total Equipment 0.00

Additional Equipment: File Name:

Mime Type:

D. Travel Funds Requested ($)*

1. Domestic Travel Costs ( Incl. Canada, Mexico, and U.S. Possessions)

2. Foreign Travel Costs

Total Travel Cost

E. Participant/Trainee Support Costs Funds Requested ($)*

1. Tuition/Fees/Health Insurance

2. Stipends

3. Travel

4. Subsistence

5. Other: 

 Number of Participants/Trainees Total Participant Trainee Support Costs 0.00

RESEARCH & RELATED Budget {C-E} (Funds Requested)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 27
Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00

RESEARCH & RELATED BUDGET - SECTIONS F-K, Budget Period 2

ORGANIZATIONAL DUNS*: 

Budget Type*: ● Project ❍ Subaward/Consortium

Organization: CORPORACION CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIG

Start Date*: 05-01-2021 End Date*: 10-31-2021 Budget Period: 2

F. Other Direct Costs Funds Requested ($)*

1. Materials and Supplies

2. Publication Costs

3. Consultant Services

4. ADP/Computer Services

5. Subawards/Consortium/Contractual Costs

6. Equipment or Facility Rental/User Fees

7. Alterations and Renovations

8 . Other: Materials translations in Spanish

9 . Other: Development of Online components for the grants management training program

10 . Other: Development of a new in-house grants management Grant Tracking System

Total Other Direct Costs

G. Direct Costs Funds Requested ($)*

Total Direct Costs (A thru F)

H. Indirect Costs

Indirect Cost Type Indirect Cost Rate (%) Indirect Cost Base ($) Funds Requested ($)*

1 . MTDC 8.0

Total Indirect Costs

Cognizant Federal Agency

(Agency Name, POC Name, and POC Phone Number)

I. Total Direct and Indirect Costs Funds Requested ($)*

Total Direct and Indirect Institutional Costs (G + H)

J. Fee Funds Requested ($)*

K. Total Costs and Fee Funds Requested ($)*

L. Budget Justification* File Name: Budget_justification.pdf Mime Type: application/pdf

(Only attach one file.)

RESEARCH & RELATED Budget {F-K} (Funds Requested)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 28
Budget justification

A. Senior/Key Person 

Jaramillo, Andres BS in administration and MBA will devote 25% effort (3.0 calendar months) as PD/PI of this 

Global Infectious Disease Research Administration Development project. He will be responsible for the overall 

leadership and coordination of the project and communications with the U.S. host institution. He will work with 

Ms. Montero in the planning, preparation and conduct of training activities at the U.S. host institution Yale 

University Schoolog Public Health and in CIDEIM, and in implementing research grants administrative changes 

to improve oversight of NIAID grant awards, compliance with NIH funding policies and Federal research 

funding requirements for NIAID-supported foreign institutions. 

Montero, Vanessa, B.Eng. and M. Eng. in industrial engineering, will devote 25% effort (3.0 calendar months) 

to this project. She will receive training in the U.S. with Mr. Jaramillo and will work with him in the planning, 

preparation and conduct of training activities at the Yale School of Public Health and in CIDEIM, and in 

implementing research grants administrative changes to improve oversight of NIAID grant awards and 

compliance with NIH funding policies and Federal research funding requirements for NIAID-supported foreign 

institutions. She will be involved in developing institutional policies and processes for sustainable 

implementation of research management practices that are compliant with NIH guidelines and requirements. 

Senior/Key Personnel costs for year 1: 

Total Senior/Key Personnel Costs: 

B. Other personnel

Villa, Luz Divia, Certified Public Accountant (CPA) with a specialization in finance, will devote 25% effort (3.0 

calendar months). Mrs. Villa is the Financial Officer of CIDEIM since 1993 and will be responsible and highly 

involved in the implementation of financial management and reporting practices in accordance with NIH 

guidelines and requirements at CIDEIM and instrumental in their dissemination to other institutions. 

Other Personnel for year 1: 

Total Other Personnel Costs: 

Total Personnel Costs for year 1: Total Personnel Costs – 18 months: 

C. Equipment

None requested.

D. Travel

International Travel:

Hands-on training in grants administration at the Yale School of Public Health 

Costs for airfare between Colombia and the U.S. estimated at trip and per diem (including hotel costs) 

estimated at /day x 15 days are included for two senior administrator(s) from CIDEIM for each year of the 

program. Total: 

NIH regional workshop on program funding and grants administration or a NIAID post-award grants policy and 

management training event

Costs for round trip airfare between Colombia and the U.S. estimated at and per diem (including hotel 

costs) estimated at /day per 5 days are included for two senior administrator(s) from CIDEIM for the first 

year of the program. Total: 

In-house training with the Grants Management Program (GMP) at NIAID in Rockville, MD

Costs for round trip airfare between Colombia and the U.S. estimated at and per diem (including hotel 

costs) estimated at /day per 5 days are included for two senior administrator(s) from CIDEIM for the 

second year of the program. Total: 

Contact PD/PI: Jaramillo Zuluaga, Andres Budget Justification Attachment Page 29
Visit to CIDEIM (Personnel of the Yale School of Public Health Research Administration office)

Costs for airfare between U.S. and Colombia estimated at /trip and per diem (including hotel costs) 

estimated at /day x 5 days are included for one professional from Yale University for first year of the 

program. Total: 

Total international travel for year 1: 

Total international travel: 

F. Other 

Products/services:

As part of sustainability initiatives:

 Costs for preparation and translation of materials ]in Spanish at for each year of the program. 

Total 

 Costs for development of Online components for the grants management training program at for 

first year and for second year of the program. Total:

 Costs for development of a new in-house Grant Tracking System at for second year of the 

program.

 Costs for webinar training and videoconferencing are included at .

Total Products/services for year 1: 

Total Products/services: $

Contact PD/PI: Jaramillo Zuluaga, Andres Budget Justification Attachment Page 30
RESEARCH & RELATED BUDGET - Cumulative Budget

Totals ($)

Section A, Senior/Key Person

Section B, Other Personnel

Total Number Other Personnel 2

Total Salary, Wages and Fringe Benefits

(A+B)

Section C, Equipment 0.00

Section D, Travel

1. Domestic

2. Foreign

Section E, Participant/Trainee Support 0.00

Costs

1. Tuition/Fees/Health Insurance 0.00

2. Stipends 0.00

3. Travel 0.00

4. Subsistence 0.00

5. Other 0.00

6. Number of Participants/Trainees 0

Section F, Other Direct Costs

1. Materials and Supplies 0.00

2. Publication Costs 0.00

3. Consultant Services 0.00

4. ADP/Computer Services 0.00

5. Subawards/Consortium/Contractual 0.00

Costs

6. Equipment or Facility Rental/User 0.00

Fees

7. Alterations and Renovations 0.00

8. Other 1

9. Other 2

10. Other 3

Section G, Direct Costs

(A thru F)

Section H, Indirect Costs

Section I, Total Direct and Indirect Costs

(G + H)

Section J, Fee 0.00

Section K, Total Costs and Fee (I + J)

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 . Received Date:

2019-07-31T17:26:48.000-04:00 Contact PD/PI: Jaramillo Zuluaga, Andres Page 31
PHS 398 Cover Page Supplement

OMB Number: 0925-0001

Expiration Date: 03/31/2020

Funding Opportunity Number: PAR-18-335 . Received Date: Tracking Number: GRANT12913604

2019-07-31T17:26:48.000-04:00

1. Vertebrate Animals Section

Are vertebrate animals euthanized? ❍ Yes ● No

If "Yes" to euthanasia

Is the method consistent with American Veterinary Medical Association (AVMA) guidelines?

❍ Yes ❍ No

If "No" to AVMA guidelines, describe method and provide scientific justification

2. *Program Income Section

*Is program income anticipated during the periods for which the grant support is requested?

❍ Yes ● No

If you checked "yes" above (indicating that program income is anticipated), then use the format below to reflect the amount and

source(s). Otherwise, leave this section blank.

*Budget Period *Anticipated Amount ($) *Source(s)

Contact PD/PI: Jaramillo Zuluaga, Andres Page 32
PHS 398 Cover Page Supplement

Funding Opportunity Number: PAR-18-335 . Received Date: Tracking Number: GRANT12913604

2019-07-31T17:26:48.000-04:00

3. Human Embryonic Stem Cells Section

*Does the proposed project involve human embryonic stem cells? ❍ Yes ● No

If the proposed project involves human embryonic stem cells, list below the registration number of the specific cell line(s) from the

following list: http://grants.nih.gov/stem_cells/registry/current.htm. Or, if a specific stem cell line cannot be referenced at this time,

check the box indicating that one from the registry will be used:

❏ Specific stem cell line cannot be referenced at this time. One from the registry will be used.

Cell Line(s) (Example: 0004):

4. Inventions and Patents Section (Renewal applications)

*Inventions and Patents: ❍ Yes ● No

If the answer is "Yes" then please answer the following:

*Previously Reported: ❍ Yes ❍ No

5. Change of Investigator/Change of Institution Section

❏ Change of Project Director/Principal Investigator

Name of former Project Director/Principal Investigator

Prefix:

*First Name:

Middle Name:

*Last Name:

Suffix:

❏ Change of Grantee Institution

*Name of former institution:

Contact PD/PI: Jaramillo Zuluaga, Andres Page 33
 

PHS 398 Research Plan

OMB Number: 0925-0001

Expiration Date: 03/31/2020

 

Funding Opportunity Number: PAR-18-335. Received Date: Tracking Number: GRANT12913604

2019-07-31T17:26:48.000-04:00

Introduction

1. Introduction to Application

(for Resubmission and Revision applications)

Research Plan Section

2. Specific Aims Specific_Aims.pdf

3. Research Strategy* Research_Strategy.pdf

4. Progress Report Publication List

Other Research Plan Section

5. Vertebrate Animals

6. Select Agent Research

7. Multiple PD/PI Leadership Plan

8. Consortium/Contractual Arrangements

9. Letters of Support Letter_of_Support.pdf

10. Resource Sharing Plan(s)

11. Authentication of Key Biological and/or

Chemical Resources

Appendix

12. Appendix

Contact PD/PI: Jaramillo Zuluaga, Andres Page 34
SPECIFIC AIMS

Centro Internacional de Entrenamiento e Investigaciones Medicas, CIDEIM, is recognized by 

COLCIENCIAS as a research center within the National System of Science, Technology and Innovation of 

Colombia. CIDEIM is dedicated to biomedical and health research on transmissible diseases, and training of 

investigators and health personnel. In order to achieve our mission, we work in concert with the public health, 

industrial and academic sectors at the national and international level. (http://www.cideim.org.co) 

CIDEIM originated in Colombia in 1961 as an International Center for Medical Research and Training 

awarded to Tulane University by the United States National Institutes of Health. Successive renewals of this 

program were followed by funding through the US NIAID ICIDR program, also awarded to and administered by 

Tulane University with the co-direction of COLCIENCIAS until 1989, when Tulane culminated its program in 

Colombia. In 1990 at the initiative of COLCIENCIAS, CIDEIM was established as a Colombian non-profit 

foundation and in 1991, successfully competed for a Tropical Medicine Research Center TMRC award from 

NIAID. Since then, CIDEIM investigators have developed collaborative research supported by subawards as 

Co-PD/PI of ICIDR, R01, D43 Fogarty Global Infectious Disease Research Training awards several 

internationally-funded grants with Yale University, as well as R21 awards with colleagues at University of 

Massachusetts and University of California San Diego, R03 awards with the University of Connecticut and 

University of Massachusetts. Direct awards to CIDEIM and hence, responsibility for grants administration have 

been limited to the past and current TMRC awards, an R03 and IRIDA R01 award. We currently lead a U19 

TMRC program (2017-2022), are subawardee for a U19 Consortium (2019-2024) led by University of 

Connecticut and have just submitted renewal for the first time as Primary applicant, of our Fogarty Global 

Infectious Disease research training program in partnership with Yale University. 

Some of the challenges in grants administration encountered recently are: updating institutional 

registrations during the pre-award phase (Grant.gov, SAMS, eRA Commons), preparation of budget and 

institutional research training grant data tables; In the award-phase, collecting Just in Time (JIT) information 

and reviewing the Notice of Award with PD/PIs; and in the post-award phase, time management and effort 

report, subrecipient management and monitoring, prior approvals request, changing an established budget, 

financial reporting and closeout and public access for publications; and in general for all phases keeping track 

with NIH policies changes. 

The overall goal of this project is to strengthen the capacity of CIDEIM to develop and implement 

institutional policies and practices for grants management that are compliant with NIH guidelines and 

requirements for administration of NIH grants, and to share this capacity with other institutions in the region. To 

achieve this goal, we will first address critical gaps in CIDEIM grants administration for current and future 

grants funded by NIH by training of CIDEIM management leaders at Yale University. Senior administrators 

trained in the U.S. will be responsible to transfer and implement these policies and practices and oversight of 

updated NIH guidelines. Second, we will design, implement and evaluate an internal training plan and 

curriculum that will provide the bases for institutionalization of sustainable capacity through continuing 

education and updating in accordance with changes in NIH guidelines; and adapt and pilot the training 

materials and curriculum for external training. Thirdly, we will review and adjust Institutional policies, 

procedures and standard operating procedures (SOPs) to meet good management practices in compliance 

with NIH requirements where certain functions do not currently have detailed instructions to support a policy or 

guideline (how, who, when, what and why) and to provide clarity of roles and responsibilities for these functions 

across CIDEIM as a whole. Lastly, we will adapt an On-line modality for components of the training program 

and develop a Grant Tracking system application. 

Specific Aims:

1. To institutionalize at CIDEIM Grants Management Best Practices for NIH grants. 

Specific Objectives: 

a) Implementation of a continuous Institutional grants management training program on NIH 

policies and requirements 

b) Revision of Institutional policies and SOPs to be in compliance with NIH requirements 

c) Development and implementation of ICT tools for good business practices for managing 

awards 

2. To disseminate Grant Management Best Practices for NIH grants in the region. 

Specific Objectives: 

a) Adaptation and piloting of the training materials and curriculum for external training 

b) Conformation of an interinstitutional community of managers of NIH grants in the region 

Contact PD/PI: Jaramillo Zuluaga, Andres Specific Aims Page 35
RESEARCH STRATEGY

RESEARCH GRANTS ADMINISTRATION/FINANCIAL MANAGEMENT PLAN

Current grants administration/financial management process at CIDEIM

The application of policies and procedures for the grant administration process is currently managed and 

administered by two units of the organization, the Research Development and Promotion Unit and the 

Administrative Unit (including the services of the accounting office of Universidad Icesi), these two units

provide support to researchers during the different phases of the grant life cycle. The activities that these Units 

support in each phase are described in Figure 1.

Figure 1. Support on the Grant Cycle in CIDEIM Adapted from: Grants.gov. (2019) (1)

To carry out the activities of the grant administration process, the organization has a Quality Management 

System, supported by manuals, procedures and formats that provides guidance for researchers for the 

development of their proposals and projects. The current schematic description of this process and the 

relevant documents and active records are summarized in Figure 2.

The current administrative / financial grant management process of the institution starts with an internal 

evaluation of the pre-proposal, to determine its alignment with institutional objectives and mission and 

compliance with scientific and ethical standards. After the pre-proposal is approved the identification of 

opportunities begins. When an opportunity has been identified for which the proposal is responsive, the full 

proposal documentation is presented according to the technical and budgetary requirements of the funding 

agency. If the funding agency approves the proposal and after completing the procedures for formalizing the

award and ethical committee approval of the protocol, consent forms and other relevant project documentation, 

the execution of the project is initiated in accordance with the project plan and approved budget. An initiation 

meeting is convened to review the project plan, responsibilities and commitments followed by signature of the 

project initiation form by the Principal investigator and all Co-investigators. Follow-up meetings are convened 

for technical and financial monitoring. During the development of the project, the different activities established 

in the project plan and budget are carried out according to the policies established by the funding agency, the 

relevant national regulations and institutional policies, with the support and advice of the different 

administrative units (Purchasing, Financial management, Quality assurance and Human resources). When the 

execution of the project is completed, technical and financial closure is conducted through a closing meeting 

and signature of close-out form by the Principal investigator. PRE-AWARD PHASE

Identifying funding 

opportunities: using the 

Grant.gov and NIH guide 

tools.

Registration in eRA Commons 

and Grants.gov

Understanding the Funding 

Opportunity Announcement 

(FOA) and SF424 instructions

Completing an application 

using the appropriate forms

Setting clear deadlines for 

internal review

Obtaining authorized official 

approval

Submitting the application

AWARD PHASE

Collecting Just in Time 

(JIT) Information

Reviewing the Notice of 

Award for meeting the 

administrative, financial, 

and programmatic 

reporting requirements of 

the award.

POST AWARD PHASE

Providing oversight of grant 

awards and compliance 

with NIH funding policies 

and Federal research 

funding requirements for 

foreign institutions.

Monitoring expenditures

Requesting Prior approvals

Reporting to the financial 

agency (RPPR and FFR)

Closing out of the award

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 36
Figure 2. Current grants administration/financial management process at CIDEIM (2).

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 37
Aspects to be improved

One of the main sources used to identify the process gaps in CIDEIM was the Foreign Organization System 

(FOS) Visit carried out in 2016 by Mrs. Clover Cobb. During this visit Mrs. Cobb identified gaps and areas of 

improvement in the process for changing an established budget, time management follow up and procedure of 

public access for publications and made recommendations that have been applied by CIDEIM and are retaken 

in this project in order to strengthen the proposed action plans and provide sustainability to these activities (3).

Another source of identification of the process gaps are the daily situations and experience of the organization 

that have been addressed in the grant management process by the organization's administration and direction. 

The gaps or processes identified for correction or improvement are the following:

In the pre-award phase

 Keeping institutional registrations up to date (Grant.gov, SAMS, eRA Commons)

 Budget and institutional research training grant applications data tables preparation

In the award-phase, 

 Collecting Just in Time (JIT) information and reviewing the Notice of Award with PD/PIs

In the post-award phase

 Effort reporting

 Subrecipient management and monitoring

 Prior approvals request

 Financial reporting and closeout

 Clarity in the roles and responsibilities related to the grant management process, especially the 

functions that support the policies and guidelines (how, who, when, what and why) associated with 

financial and administrative monitoring and supervision of projects.

A review of the procedures and tools currently available in the organization for these specific processes will be 

carried out in order to identify improvement points. This review will be done through the analysis of the 

activities, the flow of information of the process and the analysis of causes, and the correction or improvement 

plans will be framed in the cycle of continuous improvement.

Also, during the visit to the US host institution, CIDEIM administrators will identify and learn University best 

practices and tools in grants management and explore their applicability and adaptation and implementation at

CIDEIM.

The changes to be incorporated into the process will be formalized through institutional policies and 

procedures, that will later be shared and communicated to the members of the organization, through 

institutional communications and the structuring of material and tools for incorporation into continuing training

activities. The application of technological tools will also be sought in order to make information available for 

later consultation and for new staff entering the organization.

Regarding the roles and responsibilities related to the grant management process, these will be included in the 

relevant job descriptions and these functions will be communicated to all members of the organization 

involved.

U.S. host institution

The Yale School of Public Health (YSPH) is the partner U.S host institution where the two senior CIDEIM 

administrators will receive hands-on training in grants administration for up to 1 month during the award period 

(2 weeks in the first year and 2 weeks in the second year). CIDEIM has developed collaborative research and 

training supported by NIAID and NIH Fogarty Center with Yale University since 2003. YSPH is a leader in 

improving health across the globe through research, education and community engagement and has 

appropriate expertise in the management and administration of NIH grants. 

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 38
Mrs. Kathleen Fisher, Director Research Administration at Yale School of Public Health will oversee all the 

training related to this opportunity and bring over twenty-five years of experience in research administration at 

both central and departmental levels to the program.

In order to achieve the training and business practices goals of the program, the administrators from CIDEIM 

will have monthly meetings with Ms. Fisher to review and follow up training activities and 

management/business plans. At the end of month 10, it’s expected that Mrs. Fisher would visit CIDEIM to

review the progress in situ and together with the two senior administrators set up a strategy for improving 

grants management oversight and business practices at CIDEIM, this document would be signed and sent to 

NIH following the report instructions.

Overall strategy and methodology

To achieve the proposed objectives we will follow the route shown in Figure 3, starting with the training of two 

Senior Administrators in the U.S. who will be responsible to transfer to CIDEIM members involved in the grant 

management process what they learned, in order to identify and implement with them the necessary 

adjustments to institutional policies, procedures and tools, and also, to develop a grants management training 

program for sustainable compliance of NIH guidelines and requirements and help the transfer of this capacity 

to other institutions to form an interinstitutional community of individuals managing NIH grants in the region.

Additionally, the development of a Grant Tracking system will start during the project period to support the 

grants management process.

Figure 3. PERT chart of the overall strategy

TRAINING PLAN

The training plan is composed by three main phases that include: training of senior administrators from 

CIDEIM at the U.S hosting institution, Yale University School of Public Health, implementation of training at 

CIDEIM (internal) and training offered to other local or regional institutions (external).

Requirement analysis

To strengthen the 

capacity of 

CIDEIM and other 

institutions in the 

region to develop 

and implement 

institutional 

policies and 

practices in 

grants 

management that 

are compliant 

with NIH 

guidelines and 

requirements for 

the administration 

of NIH grants

Training of Senior 

Administrators 

at U.S.

Sustainability 

Initiatives Reporting

Y1-Y2

Start

Grants Management 

Training program

(Internal & External)

Hands-on training in grants 

administration at Yale 

University

Attend either a NIH regional 

workshop or a NIAID postaward training event 

Attend either a NIH regional 

workshop or a NIAID postaward training event 

Development of initial materials 

for participants and trainers 

(trainer guide in spanish)

Pilot of training materials as 

they are being translated and 

adapted in Spanish

Web-based seminars for other 

institutions 

Adjustment of Institutional 

policies and SOPs

Development of Online 

components for the grants 

management training program

Development of a new inhouse Grant Tracking System

Y1-Q2

Y2-Q1

Y1-Y2

Y1-Y2

Y1-Y2

Y1-Y2

Y1-Y2

Y2

Design

Implementation

Testing

Evaluation

1 Activities that would be initiated during the grant funding period and will continue after the funding has ended

2 Instructional system design model called ADDIE that comprises 5 dynamic and interdependent steps: Analysis, Design, Development, Implementation and Evaluation

3 The systems development life cycle (SDLC), or software development process

Analysis

Design

Development

Implementation

Evaluation

2 3

Strategy for improving grants 

management oversight and 

business practices at CIDEIM

Report changes to the local 

business practices of the 

grantee and staff training plan

Annual RPPR and Final RPPR

Invention statement and final 

FFR for award closeout

Y1

Y2

Y2

Y2

1

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 39
Training of senior administrators from CIDEIM at U.S. (Yale University)

Mr. Jaramillo visited the Office of Finance and Administration at Yale School of Public Health in November of 

2018, within the framework of the NIH Fogarty Global Infectious Diseases research training grant NIH/FIC D43

TW006589 collaboratively developed by Yale University and CIDEIM since 2003. This visit was coordinated 

with Mrs. Kathleen Fisher, Director Research Administration at Yale School of Public Health, in order to review 

and discuss the training program in grants administration and management available at Yale and how this 

program could provide the bases for this G11 application. After his visit and during the following months Mr. 

Jaramillo and Mrs. Montero developed a competency model for their respective jobs (Coordinator of Research

Promotion and Development Unit and Coordinator of the Administrative Unit, respectively) as well as for Mrs. 

Luz Divia Villa, CPA, the Financial Officer of CIDEIM, taking as a reference the competencies framework for 

administrative employees at NIH (4). Based on these competency models, priority training needs were 

identified as bases to plan the training programs of Mr. Jaramillo and Mrs. Montero at Yale University. 

Although not traveling to receive training in the U.S., Mrs. Villa will be highly involved in the implementation of 

financial management and reporting practices in accordance with NIH guidelines and requirements at CIDEIM 

and instrumental in their dissemination to other institutions. 

During Mr. Jaramillo and Mrs. Montero training at Yale University, for up to 1 month (2 weeks in the first year 

and 2 weeks in the second year), the two identified senior administrators from CIDEIM, will receive training 

organized and supervised by the Office of Finance and Administration of the School of Public Health and the 

Office of Sponsored Projects (OSP). The CIDEIM administrators will receive a training curriculum that includes 

online training modules as well as instructor-led sessions that OSP already offers periodically to their faculty 

and administrators (5). A Yale NetID will be set up for the CIDEIM administrators to have access to the online 

training modules as well other online resources that the University offers to its community for conducting and 

administering research. The training curriculum includes an Introduction to Sponsored Project Administration, 

and specific sessions on, Research Compliance Principles for Administrators, Allocating Allowable Costs, 

Effort Reporting Principles, Fly America and Open Skies Agreement, Cost Transfer Principles, Financial 

Reporting and Closeout, Cost Sharing on Sponsored Projects and Subrecipient Basics and Monitoring. 

Although, these courses and modules are offered across the calendar year, the OSP will accommodate the 

training to be achieved during their visit at Yale, as proposed in the timeline for this training summarized in 

Table 1. Other training needs that have been identified such as Changes in Project and Budget, Research 

Misconduct policy, Public Access requirements will be addressed by arranging specific meetings with people 

who have experience in those topics at the University. These CIDEIM senior administrators will also take two 

elective courses from Yale leadership Development training: InsideOut Coaching and Leading with Influence. 

Courses and module descriptions

Introduction to Sponsored Projects Administration

This 1-day program is designed to be an overview of the sponsored projects process from pre-award to post 

award. This course is intended for those who work in business offices and have the responsibility of managing 

sponsored awards or some part of the award process. The course is designed for Research Administrators 

who are new to the profession, for those who have been administering awards for years and would like a 

refresher, or for those responsible for a piece of the award management process and want an understanding of 

the entire life-cycle of an award. Successful completion of this course includes attending the class and passing 

the quiz administered at the end of class. Topics covered include: Regulatory compliance; Award basics and 

terminology; Proposal preparation, submission, negotiation and acceptance; Award setup and managing the 

award; Reporting obligations, award closeout and audits.

Research Compliance Principles for Administrators

This 1/2 day program is designed to walk attendees through the principles of research compliance 

concentrating on what business administrators need to know when managing sponsored 

awards. Main topics covered include: Conflict of Interest (COI) disclosure requirements; Human Research 

Protection Program (HRPP) and IRB reviews; Regulations, guidance and policies regarding Animal research; 

the university department of Environmental Health and Safety (EHS) and how they monitor safety concerns on 

campus; Policies and regulations regarding Export Controls of technologies and information.

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 40
Allocating Allowable Costs

The purpose of this module is to increase participants' understanding of the difference between allowable and 

unallowable costs and what constitutes an acceptable allocation methodology.

Effort Reporting Principles

This module provides administrators with a comprehensive understanding of the principles of effort reporting 

and documenting activities as it relates to sponsored awards. Topics include: Key terms, policies, procedures 

and regulations; Effort management activities from proposal through closeout; Key roles and responsibilities; 

Understanding the effort reporting lifecycle, with case studies e.g., appointing faculty and staff, proposing 

effort, charging salaries.

Fly America and Open Skies Agreement

This course is designed for anyone involved with travel arrangements charged to sponsored awards including: 

Research Administrators, Administrative Assistants, Principal Investigators, Lab Technicians, Researchers, 

etc. There are regulations that must be adhered to, and restrictions that must be followed, when making foreign 

flight reservations that will be charged to federal awards. 

Cost Transfer Principles

This module provides individuals with an understanding of university policies and procedures regarding labor 

and non-labor cost transfers associated with sponsored awards. This instructor-led course is for individuals 

who prefer interactive classroom learning; for those who took the online course but would like to discuss 

questions related to the course; or for those looking to review updated information and refresh their 

knowledge. Course objectives are to increase participants' understanding of: Federal regulations related to 

cost transfers; Sponsor and University Policy; The process to properly and efficiently prepare, document, 

approve and submit a cost transfer; and available tools and templates for these processes.

Financial Reporting and Closeout

This course is designed for administrators responsible for the financial reporting and closeout of sponsored 

awards. In this class participants will learn about: The roles and responsibilities of those involved in financial 

reporting and closeout; Policies and procedures related to these functions; 

University processes supporting sponsor requirements; The closeout process cycle; The steps necessary to 

properly close sponsored awards. This class is recommended for those who have experience working with 

Financial Status Reports (FSRs) and have been dealing with financial reporting for a minimum of 6 months.

Cost Sharing on Sponsored Projects (video)

This short video reviews the rules regarding mandatory cost-sharing, voluntary cost sharing, voluntary 

uncommitted cost sharing, in-kind/matching and charging effort commitments to an award.

Subrecipient Basics and Monitoring – Online

The content of this online module addresses the difference between subawards and procurement actions, 

requirements for establishing and monitoring subawards, and roles and responsibilities of the PI and 

administrators throughout the subaward process. Upon completion of this course participants will: Understand 

the roles and responsibilities of individuals involved in the subaward process; Be able to differentiate between 

a subrecipient and a vendor relationship; Gain a greater awareness and understanding of university policies 

and procedures regarding subrecipients; Understand the requirements and expectations 

for subrecipient monitoring and the processing of invoices; Know where to find resources to assist in 

the subaward process within the university. 

InsideOut Coaching

InsideOut Coaching is a one-day program that offers a different way of looking at coaching. It provides a 

practical and proven process for coaching others to improve and sustain enhanced performance. In this 

workshop you will learn concepts and practices that will help you and others discover your innate ability to 

respond to the performance pressures of today.

The goals of the workshop are to:

 Explore ways to improve performance in yourself and others

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 41
 Apply a process to help you make faster and directionally sound decisions

 Use a simple coaching process that:

1. Compliments current skills

2. Involves the subject matter expert in the decision-making process

3. Treats others with respect and dignity

4. Moves people to action

 Move the process to practice and apply it to real situations

Leading with influence

Leading with Influence recognizes the fact that individuals often need to use their ability to “enlist, persuade, 

and engage” others, in order to obtain results. In fact, without the ability to influence, individuals can end up 

working hard and long to strategize, innovate, and achieve their goals – and still not get the payoff they 

deserve from their efforts! In this fast-paced, hands-on workshop you will hone your influencing skills as you 

learn:

 How power, relationship, and influence methods. all affect your ability to influence

 The different influence approaches available to you, and which ones you currently use most

 An influence model that lets you choose your approach, set your plan, and enhance your results

TABLE 1. Timeline - Training at Yale University Year 1 Year 2

Instructor-Led Modality W1 W2 W1 W2

1. Introduction to Sponsored Project Administration (SPA)

2. Effort Reporting Principles

3. Leading with Influence

4. Allocating Allowable Costs

5. Research Compliance Principles for Administrators

6. Fly America and Open Skies Agreement

7. Direct Charging of F&A Costs on Sponsored Awards

8. Cost Transfer Principles

9. Financial Reporting and Closeout

10. InsideOut Coaching

Online Modality

11. Subrecipient Basics and Monitoring

12. Cost Sharing on Sponsored Projects

13. What Research Staff Need to Know About Spending Sponsored Projects Funds

14. Principle Investigator Eligibility: Who Can Be a PI?

Training at CIDEIM (internal)

Although most of the researchers at CIDEIM understand English, the majority of the administrative staff do not,

and this is a barrier for implementing NIH requirements. This situation extends to other research institutions in 

the local and regional context. Therefore, a curriculum in Spanish adapted for research administrators and staff 

from institutions in the region to fulfill NIH requirements for foreign institutions is needed. 

The two senior administrators from CIDEIM will adapt a curriculum in Spanish based on the training at Yale 

and the curriculum of training received by Mr. Jaramillo at the annual meeting of the Society of Research 

Administration (SRA) in October 2018 to obtain the “National Institutes of Health (NIH) Grants Fundamentals” 

certificate, and the NIH regional workshop (or a NIAID post-award training event) and the In-house training with 

the Grants Management Program (GMP) at NIAID that are included in this training grant . This Spanish 

language curriculum will deliver the information and corresponding sources for what research administrators 

and staff in CIDEIM need to know about NIH requirements for foreign institutions. This curriculum will be 

pertinent and applicable to other institutions in the region. 

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 42
An initial curriculum will be prepared including adaptation and translation of an introductory session/workshop 

on the National Institutes of Health (NIH) fundamentals session received by Mr. Jaramillo at the SRA annual 

meeting in 2018 and the sessions mentioned previously from Yale University, in the following order as follows: 

1. National Institutes of Health (NIH) fundamentals 

2. Introduction to Sponsored Project Administration (SPA) 

3. Research Compliance Principles for Administrators 

4. Effort Reporting Principles 

5. Financial Reporting and Closeout 

6. Allocating Allowable Costs 

7. Fly America and Open Skies Agreement 

8. Subrecipient Basics and Monitoring 

9. Cost Sharing on Sponsored Projects 

10. Cost Transfer Principles 

The session on the National Institutes of Health (NIH) fundamentals will be required to be undertaken by all the 

administrative and support staff of the Promotion and Development of Research Capacity Unit (PDRC), and 

the Administrative Unit of CIDEIM, which manages the pre and post award aspects of grants management at 

the institution. All investigators involved in projects funded by NIH and postdoctoral investigators and project 

managers will be required to complete this session. The session "Introduction to Sponsored Project 

Administration” will be required for all administrative and support staff. Similarly Administrative and support 

personnel and investigators will fulfill training sessions on topics related to specific procedures and policies (3 

to 10) essential to preparing successful applications to and managing grant awards from the National Institutes 

of Health. Audiences will vary depending on the topic and job description. 

The sessions InsideOut Coaching and Leading with influence will be incorporated into the training curriculum 

and a program for administrators, support staff and investigators interested in deepening the development of 

their competences and also the development on others competencies will be designed and tested during the 

project period. All the junior staff from the PDRC and Administrative units at CIDEIM will receive mentorship 

led by Mr. Jaramillo, Mrs. Montero and Mrs. Villa in their technical competencies for the administration of NIH 

grants. 

Initial materials in Spanish for participants and a trainer guide will be developed. Pilot versions will be tested as 

they are being developed. This curriculum will be extended and adjusted according training needs and policy 

changes at the institutional level and by NIH. 

Training offered to other local or regional institutions (External)

Using the Research Portfolio Online Reporting Tools (RePORT) https://report.nih.gov/index.aspx, the 

institutions receiving NIH awards in Colombia and in the region will be identified and invited to participate in 

some of the training activities proposed in this application, including training on site at CIDEIM and web-based 

seminars on specific topics of NIH grants administration. Also, institutions that are part of CIDEIM’s Regional 

Training Center Network that may not have NIH grant support but are interested in applying for NIH grants will 

be invited to participate in activities focused on preparing for successful applications.

Training activities on site at CIDEIM (described previously)

Web-based seminars

Specific topics of NIH grants administration will be addressed in 20 minutes presentations followed by 20 

minutes for questions and answers. Presenters will vary depending on the topic selected and the participation 

of the grants administrators from institutions in the region managing NIH funds directly or indirectly 

(subawards) will be encouraged to participate as presenters or participants. The recorded sessions and post 

seminar forum will be posted in the virtual campus of CIDEIM and registered participants will have access. 

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 43
SUSTAINABILITY INITIATIVE

Institutional oversight will be strengthened within its grants management processes, especially functions that 

do not currently have detailed instructions to support a policy or guideline (the how, who, when, what and why),

to provide clarity of roles and responsibilities for these functions across CIDEIM as a whole, as well as to 

facilitate research grants administration activities. The sustainability initiatives to be pursued through this 

project include 1) adjustment of institutional policies, procedures and standard operating procedures (SOPs) to 

effectively manage NIH research grants, 2) the development of Online components for the grants management 

training program described in the Training plan 3) the development of a new in-house grants tracking system. 

The timeline for these activities are presented under Sustainability Initiatives in Table 2.

TABLE 2 - TIMELINE OVERVIEW Year 1 Year 2

1. TRAINING PLAN Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

1.1. Training of Senior Administrators at U.S.

1.1.1. Hands-on 

University

training in grants administration at Yale 

1.1.2. Attend either a NIH 

post-award training 

regional 

event 

workshop or a NIAID 

1.1.3. In-house training with the GMP at NIAID

1.2. Grants Management 

(Internal & External)

Training program 

1.3. Development (adaptation and translation in Spanish) of 

initial materials for participants and trainers (trainer 

guide)

1.4. Pilot of training materials as they 

and adapted in Spanish

are being translated 

1.5. Web-based seminars for other institutions

2. SUSTAINABILITY INITIATIVES

2.1. Adjustment of Institutional policies and SOPs

2.2. Development 

management 

of Online components 

training program 

for the grants 

2.3. Development 

System

of a new in-house Grant Tracking 

3. REPORTING

3.1. Strategy for improving grants management 

and business practices at CIDEIM*

oversight 

3.2. Report stating what changes have been initiated or 

made to the local business practices of the grantee 

and staff training plan** 

3.3. Annual RPPR and Final RPPR

3.4. Invention statement and final FFR for award closeout

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 44
Adjustment of institutional policies, procedures and standard operating procedures (SOPs)

Institutional policies, procedures and SOPs will be revised in order to assure and harmonize their compliance 

with Federal requirements. These include: Public Access Policy, Policy on Financial Conflicts of Interest, 

Procedure for Research Misconduct, Procedures for Human Subjects, Policy and Procedures on Monitoring of 

Performance by Consortium Institutions, Procedures describing the process required to change an established 

budget, Human Subjects Research Training SOP, Grants Administration/Financial Management SOPs, etc. 

Although, CIDEIM has revised some of these in the past and this is a continuing process, during the project 

period Mr. Jaramillo and Mrs. Montero will have the opportunity to learn from Yale policies and procedures for 

grants management during their visit in year 1 and 2 and to consider these in implementing policy and 

procedural changes in CIDEIM. 

Development of Online components of the grants management training program

An online version of the 1 day course “National Institutes of Health (NIH) fundamentals” will be developed, in 

order to offer it regularly both internally and externally to national and regional institutions. An instructional 

system design model denominated ADDIE that comprises 5 dynamic and interdependent steps: Analysis, 

Design, Development, Implementation and Evaluation will be used for its development. This activity will begin 

at the end of year 1. After evaluation this strategy, the feasibility virtualizing other courses will be determined.

Development of a new in-house Grant Tracking System

CIDEIM has in-house capacity to develop web and mobile applications for research projects and also tracking 

systems for institutional purpose and use, among the tracking systems are:

1) Administrative Tracking System: allows monitoring of administrative requirements / services such as 

purchasing, travel, per diem and other expenses that are budgeted in research and capacity building 

projects.

2) Training Tracking System: allows monitoring and storage of registration data of participants in the 

training programs offered by CIDEIM, facilitating the generation of statistics and analysis of the outputs 

of the training programs within the Institutional monitoring and evaluation framework.

Additionally, an IT tool to monitor study progress (dashboard) was developed as part of a re-entry grant 

supported by the Special Programme for Research and Training in Tropical Diseases (TDR) for Dr. Maria del 

Mar Castro, Leader Clinical Research Unit at CIDEIM. This dashboard was developed using Metabase®, an 

open-source software and it can be tailored to the needs of any clinical research project. It uses data collected 

through different apps at CIDEIM to generate indicators presented to the PI and Project Manager, some of the 

indicators include enrollment rate and total number of enrolled versus sample size, project budget (by budget 

lines) and overall budget execution. 

Taking into account the experience in software development, it is proposed within the framework of this project 

to develop a new in-house Grant Tracking System that will allow the integration of previous developments, 

figure 1, for managing the Pre-Award and Post-Award processes at CIDEIM. This system will be used by all 

administrators, support staff and researchers involved in the grants management process in the institution.

Figure 4. Schematic of the integration of institutional management application 

developments. Applications that have already been implemented in CIDEIM are 

shown in Blue and the application to be developed within the framework of this 

project is shown in Green.

Contact PD/PI: Jaramillo Zuluaga, Andres Research Strategy Page 45
PHS Human Subjects and Clinical Trials Information

OMB Number: 0925-0001 and 0925-0002

Expiration Date: 03/31/2020

Tracking Number: GRANT12913604 Funding Opportunity Number: PAR-18-335 Received Date:

2019-07-31T17:26:48.000-04:00

Are Human Subjects Involved ❍ Yes ● No

Is the Project Exempt from Federal regulations? ❍ Yes ❍ No

❏ 1 ❏ 2 ❏ 3 ❏ 4 ❏ 5 ❏ 6 ❏ 7 ❏ 8

Exemption Number

Does the proposed research involve human specimens ❍ Yes ● No and/or data

Other Requested information

Contact PD/PI: Jaramillo Zuluaga, Andres Page 46
BIBLIOGRAPHY & REFERENCES

 

1. Grants.gov. (2019). Grants 101. Retrieved from: Federal Grant Cycle: https://www.grants.gov/learngrants/grants-101/grant-lifecycle.html 

2. Centro Internacional de Entrenamiento e Investigaciones Médicas. (2019). CIDEIM institutional documents 

and formats platform. Documents and formats by process: Project management. Cali, Colombia. 

3. Centro Internacional de Entrenamiento e Investigaciones Médicas. (2016). Action Plan for Addreessing the 

Compliance Issues Identified in the FOS Review Finding and Recommendations. Cali. 

4. National Institutes of Health. (2019). Working at NIH. Retrieved from: Competencies at NIH: 

https://hr.nih.gov/working-nih/competencies 

5. Yale University. (2019). It's Your Yale. Retrieved from: OSP Educational Opportunities: 

https://your.yale.edu/research-support/office-sponsored-projects/osp-educational-opportunities/osptraining-and-education 

Contact PD/PI: Jaramillo Zuluaga, Andres References Cited Page 47