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          Types of Funding Mechanisms (Activity Codes)








Types of Funding Mechanisms (Activity Codes) FacebookEmailPrintFacebookEmail     
    The NIAMS uses a variety of funding types, or mechanisms, to support research at other institutions, organizations, and facilities. The types of research programs we support are differentiated by NIH activity codes (e.g., R01, R43, etc.).The NIAMS funds the following types of grants:**Research Grants**Research Project Grants (R)Research Programs and Centers (P)Research-Related Programs (S)Supplement Programs**Training and Career Development Grants**Fellowship Programs (F)Training Programs (T)Research Career Awards (K)Loan Repayment Programs**Other Grants**Small Business (SBIR/STTR)Cooperative Agreements (U)Formula Grants (X)Research GrantsResearch Project Grants (R)**R01****Research Grants**Definition and other information provided under the R01 guidelines related links.Active R01 funding opportunities**Applications due**: Standard dates**Additional Information**:Modular GrantsR01 Guidelines**R03****Small Research Grants**Active R03 funding opportunity: PAR-22-119The Limited Competition: Small Grant Program for NIAMS K01, K08, K23, and K25 Recipients (R03) is intended to enhance the capability of NIAMS-supported K awardees to conduct research as they complete their transition to fully independent investigator status.**Duration:**No more than 2 years, not renewable.**Budget Cap:**Multi-year funds up to $100,000 direct costs for entire project period **Application Due Dates:** June 20, 2022; October 19, 2022; February 21, 2023; June 19, 2023; October 19, 2023; February 20, 2024; June 19, 2024; October 21, 2024; February 19, 2025**R13****Conference and Scientific Meeting Grants**R13 Conference Grant applicationinformation.Active R13 funding opportunitiesDefinition and other information provided under the R13 Guidelines related links.**R15****AREA Grants**Active R15 funding opportunitiesDefinition and other information provided under the R15 Guidelines related links.**R21****NIAMS High Innovation Exploratory/Developmental Research Grant Program**Active R21 funding opportunitiesNIAMS has withdrawn from NIH-wide parent R21 Exploratory/Developmental Research Grant NOFOs, PA-20-195 and PA-20-194.Instead, NIAMS accepts applications in response to NOT-AR-23-006, Notice of Special Interest (NOSI): Supporting Exploratory/Developmental Research Focused on NIAMS Core Mission Areas.Potential applicants are strongly encouraged to discuss the suitability of the project for NOT-AR-23-006 with the NIAMS Program Director for that research topic area Supported Scientific Programs | NIAMS (nih.gov).In making funding decisions on R21 applications, NIAMS will place a higher priority on projects that are:Innovative, ground-breaking projects with potential for significant impact.Projects that involve novel technology or tool development and have the potential to significantly accelerate research fields.Projects that propose the novel application of methods, technologies, or conceptual approaches from outside biomedical science to a research problem in the NIAMS mission area.Projects that will be considered a lower priority include:Projects specifically to develop preliminary data for longer-term projects in a well-established research area;New investigator starter grants;Pilot projects that do not exhibit a high degree of innovation.**Contact**: Refer to contact information for the relevant NIAMS Supported Scientific Area**Duration**: 2 years**Budget Cap**: $275,000 direct costs spread over two years**Applications Due**: Standard datesPreference in funding decisions for R21 grants under NOT-AR-23-006 will be given to projects within the NIAMS core mission areas that are especially innovative, ground-breaking and have a high potential impact on these fields. NIAMS also has funding opportunities and Notices of Special Interest (NOSIs) for R21 grants on specific topics here: Find Grant Funding | grants.nih.gov.Projects of limited time and scope that do not meet these characteristics of innovative, ground-breaking research should consider applying for a small Research Project Grant (Parent R01).Early Stage Investigators (ESIs) are encouraged to apply for Research Project Grant (Parent R01), and also the Stephen I Katz Early Stage Investigator Research Project Grant NOFOs, PAR-21-038 and PAR-21-039.**R24****Resource-Related Research Projects**Active R24 funding opportunitiesTo support research projects that will enhance the capability of resources to serve biomedical research.**R25****Research Education Program**Active R25 funding opportunitiesThe purpose of these awards is to promote an appreciation for and interest in biomedical research, provide additional training in specific areas, and/or to develop ways to disseminate scientific discovery into public health and community applications.**Science Education Partnership Award (SEPA) R25**:The overarching goal of this Science Education Partnership Award (SEPA) R25 is to encourage pre-college students (pre-kindergarten to grade 12) from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies in science, technology, engineering, and mathematics. SEPA supports: (1) classroom-based projects for pre-college students and teachers, and (2) informal science education projects conducted at outside-the-classroom venues such as science centers, museums, and libraries. Educational and research programs should be designed to increase awareness and knowledge in the scientific research areas within the NIAMS' mission.**Duration**: Up to 5 years**Budget Cap**: Direct costs limited to $250,000, excluding consortium F&A costs, annually.**Contact**: Rebecca Lenzi**Applications Due**: June 7, 2024, June 6, 2025**R34****Clinical Trial Planning Grant**Active R34 funding opportunitiesThis grant supports the administrative planning and development of a clinical trial implementation cooperative agreement (U01). Activities could include the establishment of the research team and finalizing collaborations; the development of tools for data management and oversight of the trial; the development or refinement of the trial design; the development of other essential elements of the study, such as the protocol, manual of operations, informed consent forms, recruitment strategies; and to collect feasibility data to estimate recruitment potential. This grant is not appropriate for conducting research with human subjects for the collection of preliminary data (clinical or preclinical) or the collection of prospective data to support the rationale for a clinical trial.**R41/R42****Small Business Technology Transfer (STTR) Program**Active R41/R42 funding opportunitiesThe STTR program is a set-aside program designed to support innovative research that has the potential for commercialization of the subject research conducted cooperatively by a small business concern and a research institution. Innovation and the potential for commercialization are two important aspects of the review criteria considered in the scientific and technical merit evaluation process. At least 40% of the research project is to be conducted by the small business concern, and at least 30% of the work is to be conducted by the single, partnering research institution.Read more about NIAMS Small Business Grants.**SBIR/STTR:****FAQ Page****Contact**: Xibin Wang**Applications Due**: Standard dates**Additional Information**: Office of Extramural Research: Small Business Innovation Research (SBIR) and Small Business Technology (STTR) Programs**R43/R44****Small Business Innovation Research (SBIR) Program**Active R43/R44 funding opportunitiesThe SBIR program is a set-aside program designed to support innovative research that has the potential for commercialization of the subject research conducted by a small business concern. Innovation and the potential for commercialization are two important aspects of the review criteria considered in the scientific and technical merit evaluation process.Read more about NIAMS Small Business Grants.**SBIR/STTR:****FAQ Page****Contact**: Xibin Wang**Applications Due**: Standard dates**Additional Information**: Office of Extramural Research: Small Business Innovation Research (SBIR) and Small Business Technology (STTR) Programs**R61/R33-RISK****Research Innovations for Scientific Knowledge (RISK)**Active R61/R33 funding opportunitiesFocuses on innovative research within the NIAMS mission by encouraging applicants to pursue unusual observations, test imaginative hypotheses, investigate creative concepts, and build ground-breaking paradigms, all of which deviate significantly from the current prevailing theories or practice. Support will be provided for up to 2 years (R61 Phase) to perform critical experiments that rigorously test the proposed concept. The outcomes of these critical experiments will be the central determining factor for the activation of the R33 Phase. The R33 Phase will provide up to 1 additional year of support to further validate and explore the innovative concept. NIAMS strongly recommends applicants submit an X02 pre-application.**Duration**: up to 2 years for the R61 Phase and 1 year for the R33 Phase**Budget Cap**: $250,000 direct costs per year**Applications Due**: By RFA onlyResearch Programs and Centers (P)**P30****NIAMS Resource-based Centers (P30)**Active Resource-based P30 funding opportunitiesProvides critical research infrastructure, shared facilities, services, and resources to groups of investigators, with the broad overall goal of accelerating, enriching, and enhancing the effectiveness of ongoing basic, translational, and clinical research and promoting new research within the NIAMS mission. A strong biomedical research community conducting NIAMS mission-relevant research is a prerequisite for establishment of a Resource-based Center. The components of a Resource-based Center include one or more resource cores and an administrative core that includes an Enrichment Program.**Duration**: 5 years**Budget Cap**: $500,000 direct costs**Additional Information**: Suggested exhibits for P30 applications [ PDF format ]**FAQs**: Resource-based Centers (P30)**Contact**: NIAMS Centers Program**P30-CCCR****NIAMS Core Centers for Clinical Research (CCCR)**Active P30-CCCR funding opportunitiesProvides avenues to advance the methodological sciences that support clinical research within and across the NIAMS’ portfolio of diseases. Will address existing and future research needs in musculoskeletal, rheumatologic, and skin diseases by fostering the development, implementations, and inclusion of novel data, analytical methods, metrics, and outcome measures into clinical research at the institutional, local, and national level. This funding opportunity will not support core centers (or activities within centers) focused on the generation of biological or genetic data or the development of novel technologies for such generation.**Duration**: 5 years**Budget Cap**: $500,000 direct costs**FAQS:**NIAMS Core Centers for Clinical Research (CCCR) - FAQs**Contact**: NIAMS Centers Program**P50-CORT****Centers of Research Translation (CORT)**Active P50-CORT funding opportunitiesTo promote translational research through a multidisciplinary approach on a disease specific theme. A CORT should have both basic and clinical research components.**Duration**: 5 years**Budget Cap**: $1,000,000 direct costs**Applications Due**: By RFA only**Additional Information**: Read our CORT FAQs.**Contact**: NIAMS Centers Program**P50-ORWH****Specialized Centers of Research on Sex and Gender Factors Affecting Women’s Health (SCOR)**The Office of Research on Women's Health (ORWH) serves as a focal point for women's health research at the NIH. The ORWH promotes, stimulates, and supports efforts to improve the health of women through biomedical and behavioral research. ORWH works in partnership with the NIH Institutes as well as the Food and Drug Administration (FDA) to ensure that women's health research is part of the scientific framework at NIH and throughout the scientific community. The ORWH announces the Specialized Centers of Interdisciplinary Research on Sex and Gender Factors Affecting Women's Health (SCOR) program. These centers will provide new opportunities for interdisciplinary approaches to advancing studies on how sex and gender factors affect women's health. Each SCOR should develop an interdisciplinary research agenda bridging basic and clinical research on sex/gender factors underlying a priority women’s health issue.**Duration**: 5 years**Budget Cap**: $750,000 direct costs**Applications Due**: By RFA only**Contact**: NIAMS Centers ProgramResearch-Related Programs (S)**S06****Minority Biomedical Research Support - MBRS**Active S06 funding opportunitiesTo strengthen the biomedical research and research training capability of ethnic minority institutions, and thus establish a more favorable milieu for increasing the involvement of minority faculty and students in biomedical research.**S10****Biomedical Research Support Shared Instrumentation Grants (NCRR)**To make available to institutions with a high concentration of NIH extramural research awards, research instruments which will be used on a shared basis.**SB1****Commercialization Readiness Program**Active SB1 funding opportunitiesTo support follow-on awards to small businesses for technology development, testing, evaluation, and commercialization assistance for SBIR or STTR Phase II technologies or for awards to small businesses to support the progress of research, research and development, and commercialization conducted under the SBIR or STTR programs to Phase III.Supplement Programs**Administrative Supplements to Existing NIH Grants and Cooperative Agreements** See funding opportunity for guidelines: https://grants.nih.gov/grants/guide/pa-files/PA-20-272.htmlThese supplements are restricted to budgetary requests arising from unusual or exceptional circumstances (e.g., natural disasters) and emergencies. The NIAMS will only consider requests for administrative supplements to provide support for the accomplishment of the original aims of a project in circumstances in which these unanticipated costs have arisen, placing the overall success of the project in question. Requests related to lapses in funding and possible new directions will not be considered. The NIAMS has very limited funds for such supplements, and approves such requests infrequently. To award new funds for a significant expansion of a project’s scope a grantee must apply for a competing revision and undergo peer review. Before proceeding with any supplement request, PIs are advised to contact their program officer to discuss scientific need and their grants management specialist to discuss budget and policy issues.The National Institutes of Health (NIH) has recently posted guidance regarding administrative supplements. The announcement informs principal investigators (PIs) holding specific types of NIH research grants that funds may be available for administrative supplements.Administrative supplements applications are accepted year round except from June 1 through October 1.**Please note**:  These dates are not applicable to administrative supplements solicited through NOSIs.**Supplement to Advance Research (STAR)** The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) offers the Supplement to Advance Research (STAR) program to promote innovation and exploration of high-risk ideas by providing supplemental funding to early career stage investigators. The STAR Program will support activities that effectively allow these investigators to expand and explore new opportunities within the broader scope of currently funded, peer-reviewed research project to facilitate the transition from a single, structured research project to a research program. For the purpose of the STAR Program, NIAMS defines these investigators as those who have successfully renewed a first NIAMS-supported R01 which was received no earlier than 2009 with Early Stage Investigator (ESI) status. Applications for the STAR program must be submitted in the second or third year of the current award.For additional information and application due dates, see the funding opportunity here: PA-18-914For more information, contact the STAR coordinator at niamsstar@mail.nih.gov**Diversity Supplements** PA-21-021: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)PA-18-837: Administrative Supplements to Promote Diversity in Research and Development Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)Diversity Supplement Program Guidelines**Re-Entry Supplements** See funding opportunity for guidelines: Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry and Re-integration into Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed)NIAMS accepts and reviews applications on a continuous basis between October 1 and May 31. Applications received outside of these dates will be returned, but could be resubmitted during the during the next receipt period if appropriate.  NIAMS strongly encourages the PI of the parent research grant to contact both the scientific contact listed in this table and the NIAMS Program Officer of that grant. NIAMS strongly encourages electronic submission of the completed application request, including all appropriate signatures and supporting documents, via eRA Commons or Grants.gov. Applicants are encouraged to send an e-mail to the scientific contact alerting them to the submission of the application:NIAMSDiversity Program@mail.nih.govA NIAMS grant may only support one Re-Entry Supplement candidate at any given time.**Family-Friendly / Life Events Supplements**NOT-OD-23-031 - Notice of Special Interest: Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and ScholarsNOT-OD-023-032 - Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards**Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars Guidelines.****Notice Number**: NOT-OD-23-031NIH FAQs**Purpose**:This supplement program is intended to ensure continuity of research among recipients of mentored career development (K) awards by providing supplemental research support to help sustain the investigator's research during critical life events.Data from The National Science Foundation (NSF) demonstrates that Investigators, especially women, are more likely to cite family responsibilities as a reason for leaving the work force. Pregnancy and childbirth appear to be a significant contributor to the underemployment of women scientists and engineers, given that pregnancy can impact research productivity.The demands of childbirth and subsequent primary caregiving responsibilities may necessitate changes to career goals and alter researchers career trajectories, depriving the scientific workforce of an important source of talent and undermining NIH's investment in promising avenues of new research.For the purposes of this program, critical life events that would qualify for consideration include childbirth, adoption, serious personal health issues or illness and/or debilitating conditions, high-risk pregnancy, and primary caregiving responsibilities of an ailing spouse, child, partner, parent or a member of the immediate family during the project.**Eligibility**:To be eligible, PIs must hold an active NIAMS K award. Eligible activity codes include K01, K08, K23, K25, and K99 / R00 (on the mentored K99 portion of the K99 / R00).Supplement applications submitted to NIAMS must provide documentation that, at the time of the award, the PI:will give birth within the next 3 months or has given birth in the past 12 months.is acting as the primary caregiver within the first year of the birth or adoption of a child.is acting as the primary caregiver for an ailing spouse, child, partner, or a member of the immediate family.is experiencing a serious personal health issue or illness and/or debilitating condition.Only one parent at a time can be designated as the primary caregiver to a child.The supplement is not retroactive. At least 6 months of support must be remaining on the grant at the start of the supplement award. Supplements may not be awarded on a grant that is a No Cost Extension (NCE).**Budget**:The supplement may be used to support additional personnel, computational services, supplies and equipment that will promote the continuity of the career development research project during a period in which the PD/PI experiences critical life events which have the potential to impact research progress or potential productivity. Administrative supplements must support the scope of the original project and provide support during the period of critical life event.The administrative supplement budget is limited to 1 year.The application budget cannot exceed a maximum direct cost of $70,000; applicable F & A (indirect) cost can also be requested.**Application Due Dates**:NIAMS has 2 receipt dates for this program: May 1st and Nov 1st. Funds are expected to be awarded by July 1st and Jan 1st, respectively.**Application content**:Supplement requests must be submitted in accordance with the parent program announcement:Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial  Optional ) PA-20-272 or its subsequent reissued equivalentSupplement requests should be submitted electronically. The process for Streamlined Submissions using the eRA Commons cannot be used for this initiative.All instructions in the SF424 (R&R) Application Guide, PA-20-272 and  NOT-OD-23-031 must be followed. Applicants must include NOT-OD-23-031 in box 4b of the SF424 R&R form. Applications should include a letter signed by the Institutional Business Official certifying the PI's eligibility for the supplement award.The following items are to be included in the PHS 398 Career Development Award Supplemental Form:**1. Research Strategy (6-page limit) to include:**Progress to date. The original specific aims of the research project and a brief progress report including the roles of personnel working on the project.Statement of need: a description of how the critical life event has impacted or will impact progress on the award and the ongoing or pending work to be managed during the period of the supplement award and how the administrative supplement will increase or preserve the likelihood for the project to succeed.Budget justification. A description of how the supplement funds will be used to offset the impact to the research program as a result of the critical life event.Available other support. A description of any additional funds available to ensure sustained research and the availability of carryover funds from previous years and any local assistance, including matching funds or specified 'in kind' support.**2. Candidate Information and Goals for Career Development attachment (2-page limit):**Personal statement of the applicant, including long-term research objectives and career goals, a justification for the supplement support, and a plan to return to full productivity at the end of the supplement period.**3. Institutional Commitment to Candidate's Research Career Development attachment (1-page limit):**Institutional letter of commitment that includes details of resources and mentoring to be made available to the applicant to ensure strong productivity on the parent grant. The letter should also detail the institutional commitment to the applicant's return to full productivity and research career trajectory at the end of the supplement period.**Review of Applications:**A committee of NIAMS program and grants management staff will review requests submitted to NIAMS. NIAMS will support the most meritorious request, based upon availability of funds.**Administrative Supplement for Continuity of Biomedical Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards Guidelines****Notice Number:** NOT-OD-23-032NIH FAQs**Purpose:**The overarching goal of this pilot program is to enhance the retention of investigators facing critical life events who are transitioning to the first renewal of their first independent research project grant award or to a second new NIH research project grant award.Data from the National Science Foundation (NSF) demonstrates that Investigators, especially women, are more likely to cite family responsibilities as a reason for leaving the work force. Pregnancy and childbirth appear to be a significant contributor to the underemployment of women scientists and engineers, given that pregnancy can impact research productivity.The demands of childbirth and subsequent primary caregiving responsibilities may necessitate changes to career goals and alter researchers career trajectories, depriving the scientific workforce of an important source of talent and undermining NIH's investment in promising avenues of new research.For the purposes of this program, critical life events that would qualify for consideration include childbirth, adoption, serious personal health issues or illness and/or debilitating conditions, high-risk pregnancy, and primary caregiving responsibilities of an ailing spouse, child, partner, parent or a member of the immediate family during the project.**Eligibility:**To be eligible, PDs/PIs must hold only one active NIH Research Project Grant. Eligible award codes include: DP1, DP2, DP5, R01, R00, R15, R34, R21 and U01.Supplement applications submitted to NIAMS must provide documentation that, at the time of the award, the PI:will give birth within the next 3 months or has given birth in the past 12 months.is acting as the primary caregiver within the first year of the birth or adoption of a child.is acting as the primary caregiver for an ailing spouse, child, partner or a member of the immediate family.Is experiencing a serious personal health issue or illness and/or debilitating condition.Only one parent at a time can be designated as the primary caregiver to a child.The supplement is not retroactive. At least 6 months of support must be remaining on the grant at the start of the supplement award. Supplements may not be awarded on the grant that is in a No Cost Extension (NCE).**Budget:**The supplement may be used to support additional personnel, computational services, supplies, and equipment that will promote the continuity of the career development research project during a period in which the PD/PI experiences critical life evens which have the potential to impact research progress or potential productivity. Administrative supplements must support work within the scope of the original project and provide support during the period of the critical life event.The administrative supplement budget is limited to 1 year.The application budget cannot exceed a maximum direct cost of $70,000; applicable F&A (indirect) cost can also be requested.**Application Due Dates:**NIAMS has 2 receipt dates for this program: May 1st and Nov 1st. Funds are expected to be awarded by July 1st and Jan 1st, respectively.**Application content:**Supplement requests must be submitted in accordance with the parent program announcement: Administrative supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Critical Trial Optional)PA-20-272 or its subsequent reissued equivalent.Supplement request should be submitted electronically. The process for Streamlined Submissions using the eRA Commons cannot be used for this initiative.All instructions in the SF424 (R&R) Application Guide, PA-20-272, and  NOT-OD-23-032 must be followed. Applicants must include NOT-OD-23-032 in box 4b of the SF424 R&R form. Applications should include a letter signed by the Institutional Business Official certifying PI's eligibility for the supplement award.The following items are to be included in the **PH 398 Research Plan Form**:**1. Research Strategy (6-page limit) to include**:**Progress Date:** The original specific aims of the research project and a brief progress report including the roles of personnel working on the project.**Statement of need:** A description of how the critical life event has impacted or will impact progress on the award and the ongoing or pending work to be managed during the period of the supplement award and how the administrative supplement will increase or preserve the likelihood for the project to succeed.**Budget justification:** A description of how the supplement funds will be used to offset the impact to the research program as a result of the critical life event.**Available other support:** A description of any additional funds available to ensure sustained research and the availability of carryover funds from previous years and any local assistance, including matching funds or specified 'in kind' support.**2. R&R Other Project Information, Other Attachments:****Personal Statement (2-page limit)** of the applicant, including long-term research objectives and career goals, a justification for the supplemental support, and a plan to return to a full productivity at the end of the supplement period.**Institutional Letter of Commitment (1-page limit)** that includes details of resources and mentoring to be made available to the applicant to ensure strong productivity on the parent grant. The letter should also detail the institutional commitment to the applicant's return to full productivity and research career trajectory at the end of the supplement period.**Review of Applications:**A committee of NIAMS program and grants management staff will review request submitted to NIAMS. NIAMS will support the most meritorious request, based upon availability of funds.Training and Career Development GrantsFellowship Programs (F)**F30****Predoctoral M.D./Ph.D. and Other Dual Doctoral Degree Individual National Research Service Award**Active F30 funding opportunitiesTo provide predoctoral support for individual M.D./Ph.D. and other dual doctoral degree students to extend their potential for a career in research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required.**Duration**: Up to 6 years**Commitment**: Full-time research fellowship**Provisions**: NRSA Stipends, Tuition/Fees, and Institutional Allowance**Applications Due**: Standard dates**F31****Predoctoral Individual National Research Service Award**Active F31 funding opportunitiesTo provide predoctoral support of research leading to the Ph.D. or equivalent research degree for individuals to extend their potential for a career in research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required.**Duration**: Up to 5 years**Commitment**: Full-time research fellowship**Provisions**: NRSA Stipends, Tuition/Fees, and Institutional Allowance**Applications Due**: Standard dates**F32****Postdoctoral Individual National Research Service Award**Active F32 funding opportunitiesTo provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required. Requires M.D. or Ph.D. or equivalent.**Duration**: Up to 3 years**Commitment**: Full-time research fellowship**Provisions**: NRSA Stipends, Tuition/Fees, and Institutional Allowance**Applications Due**: Standard dates**F33****Senior Fellowship**Active F33 funding opportunitiesFellowships to provide opportunities for experienced scientists to make major changes in the direction of research careers, to broaden scientific background, and to acquire new research capabilities regarding arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required.**Level**: At least 7 years postdoctoral (this is a "sabbatical" award)**Duration**: Up to 2 years**Commitment**: Full-time research fellowship**Provisions**: NRSA Stipends, Tuition/Fees, and Institutional Allowance**Applications Due**: Standard datesTraining Programs (T)**T32****Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants**Active T32 funding opportunitiesThe NIAMS Training Program (T32)NIAMS offers these grants to enable institutions to make NRSAs for predoctoral and postdoctoral research training to individuals selected by them in the fields of arthritis, muscle, bone, musculoskeletal, and/or skin diseases.**Duration**: 5 year institutional grant (renewable).**Provisions**: NRSA Stipends, Tuition/Fees, and Training Related Expenses**Applications Due**: May 25 onlyResearch Career Awards (K)Note: For supplements to funded research grants to support training and career development of under-represented minorities, people from socioeconomically disadvantaged backgrounds or persons with disabilities, please see Supplement Programs**K01****Mentored Research Scientist Development Awards**Active K01 funding opportunitiesTo provide research scientists with an additional period of sponsored research experience as a way to gain expertise in a research area new to the applicant or in an area that would demonstrably enhance the applicant's scientific career. These awards are generally reserved for individuals interested in switching to a new research field, for individuals who have interrupted their career because of illness or pressing family care responsibilities, or for faculty at minority institutions who wish to enhance their capacity for independent research.**Duration**: Up to 5 years**Provisions**: Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $20,000.**Applications Due**: Standard dates**K08****Mentored Clinical Scientist Development Investigator Awards**Active K08 funding opportunitiesTo support supervised study and research for individuals with clinical doctoral degrees who have the potential to develop into productive, clinical investigators.**Duration**: 3 to 5 years**Provisions**: Support is provided for salary up to $100,000 for a minimum 75% effort (with the exception of orthopaedic surgeons, who may devote a minimum of 50% effort*), fringe benefits, and other research expenses up to $30,000.**Applications Due**: Standard dates*Please see NOT-AR-16-012**K23****Mentored Patient-Oriented Research Career Development Award**Active K23 funding opportunitiesTo support supervised study and research for individuals with clinical doctoral degrees who have the potential to develop into productive, clinical investigators focusing on patient-oriented research. Candidates must have completed their specialty and, if applicable, subspecialty training prior to receiving an award.**Duration**: 3 to 5 years**Provisions**: Support is provided for salary up to $100,000 for a minimum 75% effort (with the exception of orthopaedic surgeons, who may devote a minimum of 50% effort*), fringe benefits, and other research expenses up to $30,000.**Applications Due**: Standard dates*Please see NOT-AR-16-012**K24****Midcareer Investigator Award in Patient-Oriented Research**Active K24 funding opportunitiesTo support protected time for clinicians to allow them time for patient-oriented research and to act as mentors for beginning clinical investigators. NIAMS only accepts new/resubmission applications from Associate Professors. A K24 recipient promoted to Full Professor during the award period remains eligible to apply for a renewal application. Candidates must be clinician-scientists working in a research environment, conducting patient-oriented research. The K24 applicant (new or renewal) is required to have active, independent, peer-reviewed R01 or R01-like grant funding (excluding grants in no cost extension), which includes peer-reviewed research grants from other federal sources, private foundations, or industry at the time of application.**Duration**: 3 to 5 years.**Provisions**: Support is provided for salary up to the NIH Salary Cap for 25-50% effort, fringe benefits, and other research expenses up to $50,000.**Applications Due**: Standard dates**K25****Mentored Quantitative Research Career Development Award**Active K25 funding opportunitiesTo support supervised study and research for investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have made a commitment to focus their research endeavors on biomedical research. This mechanism is aimed at research-oriented scientists with experience at the level of junior faculty who have the potential to integrate their expertise with biomedicine and to develop into productive investigators.**Duration**: 3 to 5 years.**Provisions**: Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $25,000.**Applications Due**: Standard dates**K99/R00****NIH Pathway to Independence (PI) Award**Active K99/R00 funding opportunitiesMaximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) (K99/R00)The Pathway to Independence Award is uniquely designed to facilitate the transition of outstanding postdoctoral candidates from mentored to independent research positions. The award contains two components; a mentored (K99) phase that can last up to 2 years and an independent (R00) phase, which will have a duration of 3 years. The objective of the program is to facilitate research independence earlier in an investigator's career. Investigators complete supervised research, and apply for an independent research faculty position, during the mentored phase of the award. Activation of the independent award phase is administrative, and is contingent upon the investigator securing an independent research position. Eligible candidates will have no more than 4 years of postdoctoral research at the time of application (initial or amended). Award recipients are expected to obtain R01 support during the independent phase of the award.Provisions: for mentored candidates in an extramural institution, NIAMS will provide up to $60,000 per year for salary support (up to $75,000 per year for applicants with an M.D. degree), plus fringe and up to $20,000 for research support costs. Budget details for mentored candidates in the NIH intramural program will be negotiated with the sponsoring laboratory and will be cconsistant with offers to scientists in comparable positions.Loan Repayment Programs (LRP)**L30/L40****LRP Loan Repayment Programs**The NIAMS welcomes applications to the NIH Loan Repayment Program. We are interested in applications that meet the eligibility requirements for either the Clinical Research Program or the Pediatric Research Program. We are particularly interested in applications from physician-scientists. Please visit the NIH Loan Repayment Program to learn about eligibility information, application instructions and more.**Contact**: Neil Robertsor**LRP Information Center**: 866-849-4047Other GrantsOther Small Business Funding Opportunities**SB1****Commercialization Readiness Program**Active SB1 funding opportunitiesTo support follow-on awards to small businesses for technology development, testing, evaluation, and commercialization assistance for SBIR or STTR Phase II technologies or for awards to small businesses to support the progress of research, research and development, and commercialization conducted under the SBIR or STTR programs to Phase III.**U44****Small Business Innovation Research (SBIR) Cooperative Agreements—Phase II**Active U44 funding opportunitiesTo support in-depth development of R&D ideas whose feasibility has been established in Phase I and that are likely to result in commercial products or services (also Fast Track).**Contact**: Xibin Wang (SBIR/STTR)Cooperative Agreements (U)**U01****Research Project Cooperative Agreements**Active U01 funding opportunitiesThese are agreements between NIH and the award recipient in which the NIH acts as the partner in the research effort for projects similar to grants.**U19****Research Program—Cooperative Agreements**Active U19 funding opportunitiesTo support a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. A cooperative agreement research program generally involves the organized efforts of large groups, members of which are conducting research projects designed to elucidate the various aspects of a specific objective. Substantial Federal programmatic staff involvement is intended to assist investigators during performance of the research activities, as defined in the terms and conditions of award. The investigators have primary authorities and responsibilities to define research objectives and approaches, and to plan, conduct, analyze, and publish results, interpretations and conclusions of their studies. Each research project is usually under the leadership of an established investigator in an area representing his/her special interest and competencies. Each project supported through this mechanism should contribute to or be directly related to the common theme of the total research effort. The award can provide support for certain basic shared resources, including clinical components, which facilitate the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence.**U24****Resource-Related Research Projects—Cooperative Agreements**Active U24 funding opportunitiesTo support research projects contributing to improvement of the capability of resources to serve biomedical research.**UH2****Exploratory/Developmental Cooperative Agreement Phase I**Active UH2 funding opportunitiesThese are agreements between NIH and the award recipient in which the NIH acts as the partner in the research effort for projects similar to grants.**UH3****Exploratory/Developmental Cooperative Agreement Phase II**Active UH3 funding opportunitiesThe UH3 award is to provide a second phase for the support for innovative exploratory and development research activities initiated under the UH2 mechanism. Although only UH2 awardees are generally eligible to apply for UH3 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants demonstrating progress equivalent to that expected under UH2.**UG3****Phase 1 Exploratory/Developmental Cooperative Agreement**Active UG3 funding opportunitiesAs part of a bi-phasic approach to funding exploratory and/or developmental research, the UG3 provides support for the first phase of the award. This activity code is used in lieu of the UH2 activity code when larger budgets and/or project periods are required to establish feasibility for the project.**U44****Small Business Innovation Research (SBIR) Cooperative Agreements—Phase II**To support in-depth development of R&D ideas whose feasibility has been established in Phase I and that are likely to result in commercial products or services (also Fast Track).Read more about NIAMS Small Business Grants.**Contact**: Xibin Wang (SBIR/STTR)Pre-Applications (X)**X02****Preapplication**Active X02 funding opportunitiesA program to invite eligible institutions to submit a pre-application (also known as a “white paper” or “précis”) to facilitate certain approaches or economies, such as reducing burden on the applicant community, for a funding opportunity.


Last Updated: January 2024


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