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                    Research & Funding
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                    Digestive Diseases Clinical Research & Epidemiology

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        Research Programs & Contacts
        Digestive Diseases Clinical Research & Epidemiology
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        Disease Biology
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                Clinical DevelopmentDigestive Diseases Clinical Research & Epidemiology
    Patient-oriented clinical research and epidemiology research in digestive diseases.
    The Digestive Diseases Clinical Research and Epidemiology program supports patient-oriented clinical research and epidemiology research in digestive diseases.  The program supports small clinical studies focused on research that is innovative and of potential high impact and should lead to full-scale clinical trials.  The program encourages Phase III clinical trials, which are typically multi-center and involve several hundred patients randomized to two or more treatments, one of which is usually a placebo.  The aim of such trials is to provide evidence for support of, or a change in, health policy or standard of care.  Studied treatments may include pharmacologic, nonpharmacologic, and behavioral interventions for disease prevention, prophylaxis, diagnosis, or therapy.  The program’s research portfolio includes studies on:  Helicobacter pylori; inflammatory bowel disease; functional bowel disorders and constipation; nonulcer dyspepsia; celiac disease; intestinal failure; short gut syndrome; and small bowel transplantation.
This program also serves as a focal point for the collection, analysis, and dissemination of data on digestive diseases and their complications.  The program encourages research that addresses risk factors for disease occurrence and disease prognosis or natural history.  The program also supports databases and biological repositories that advance clinical and epidemiological studies in digestive diseases and nutrition.  Specific areas of focus for this program include:  identifying the data needed to address the scientific and public health issues in digestive diseases and nutrition; addressing the epidemiology of digestive diseases and nutritional disorders of public health significance, with particular emphasis on national surveys and their follow-up; promoting the timely availability of reliable data to pertinent scientific, medical, and public organizations; standardizing data collection and terminology in clinical and epidemiological research; and working closely with members of the scientific community to develop investigator-initiated research in digestive diseases and nutrition epidemiology.
    NIDDK Program Staff
        Dana K. Andersen, M.D.
                    Observational and Investigational Clinical Research; Biomedical Devices, Surgical Interventions, and Medications
                Jose Serrano, M.D., Ph.D.
                    Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis; Drug Induced Liver Injury; Clinical Research on GI Diseases
                Aynur Unalp-Arida, M.D., M.Sc., Ph.D.
                    Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition
Recent Funding Opportunities
                    View More Recent Funding Opportunities
        Posted:
                                4/10/2024
                            PA-24-184
                    Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Required)
                    
                    Summary
                Posted:
                                4/9/2024
                            PA-24-185
                    Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Not Allowed)
                    
                    Summary
                Posted:
                                4/2/2024
                            PAR-24-206
                    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
                    
                    Summary
                Posted:
                                3/27/2024
                            NOT-OD-24-078
                    Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research
                    
                    Summary
                Posted:
                                3/26/2024
                            RFA-NS-25-012
                    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
                    
                    SummaryView More Recent Funding Opportunities
Related Links
Human Subjects Research
    NIDDK Active Trials in Digestive Disease
    View related clinical trials from ClinicalTrials.gov.
    NIH Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area.
    Visit the NIH’s Center for Scientific Review website to search for study sections.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

Meetings & Workshops
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        Last Reviewed October 2023 Contact Us
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