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                Clinical DevelopmentDiabetes Centers
    Enhancing and extending the effectiveness of diabetes research by encouraging collaboration among investigators from relevant disciplines.
    NIDDK Program Staff
        Corinne M. Silva, Ph.D.
                    The role of circadian rhythms and sleep in metabolic diseases; mechanisms by which the intrauterine environment alters metabolic responses in the offspring; Diabetes Research Centers.
                Pamela L. Thornton, Ph.D.
                    Health Equity and Translational Research; Centers for Diabetes Translation Research (P30) Program
    **On this page:**
Funding for Diabetes Centers
    Resources and Services Available from Diabetes Centers
    Diabetes Research Centers (DRCs)
        Centers for Diabetes Translation Research (CDTRs)
    Related Links
    Research Resources
    Additional Research Programs
    Meetings & WorkshopsFunding for Diabetes Centers
NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. The program supports and enhances interdisciplinary research in diabetes but does not directly fund major research projects; rather, it provides core resources to enhance the efficiency, productivity, and interdisciplinary cooperation of Center investigators conducting research in diabetes and related areas of endocrinology and metabolism.
NIDDK funds Diabetes Centers via P30. Please see the Diabetes Research Centers (DRC) application resources or the  Centers for Diabetes Translation Research (CDTR) application resources for tables and additional documentation required in all Diabetes Centers applications.
Centers are funded on the following review schedule:
CDTR: announcements are published once every 5 years
    DRC: are published three times every 5 yearsResources and Services Available from Diabetes Centers
NIDDK Diabetes Centers generate investigative resources that are available to the broader research community. Centers also provide short-term enrichment activities, as well as pilot and feasibility programs that fund small research grants designed to generate preliminary data for larger grant applications.
For more information about each Diabetes Center’s aims, shared resources, pilot and feasibility programs, enrichment programs, and activities, please visit their websites:
Diabetes Research Centers (DRCs)
The DRCs promote new discoveries and enhance scientific progress through support of cutting-edge basic and clinical research related to the etiology and complications of diabetes, with the goal of rapidly translating research findings into novel strategies for the prevention, treatment and cure of diabetes and related conditions.  DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes and related endocrinology and metabolism research by providing shared access to specialized technical resources and expertise and by creating an environment that supports important and innovative research.  DRCs are expected to raise awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally.
**Albert Einstein-Mount Sinai Diabetes Center**
**Research Aims:**Investigations primarily target the minority and other served under populations prevalent among the residents of the Bronx and Manhattan, adjacent Westchester county, and other boroughs comprising New York City. The primary research efforts encompass both type 1 (T1DM) and type 2 (T2DM) diabetes and related metabolic defects.
    **Activities & Services**
    Cores
        Animal Physiology Core
            Immuno-Technology
            The Human Islet & Adenovirus
            Stable Isotope & Metabolomics
            Translational Research
        Pilot & Feasibility Program
        Supports
            New investigators with interests in diabetes or related metabolic and endocrine disorders, including junior investigators shifting from mentor-based research to an independent career. Meritorious applications from new investigators receive priority for funding.
                Established faculty in other areas who wish to apply their expertise to diabetes research.
                Diabetes Center members who wish to explore a new area of research that constitutes a substantive departure from their on-going work.****Boston Area****
**Research Aims:**A consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes, and their associated microvascular and atherosclerotic complications.
    **Activities & Services**
    Cores
        Cell Biology and Morphology Core
            Metabolic Physiology Core
            Pancreatic Islet Core
            Transgenic Core
        Pilot & Feasibility Program****Columbia University****
**Research Aims:**The DRC provides a central support structure to foster collaboration among investigators working in the areas of diabetes, immunology, transplantation, obesity and arteriosclerosis/lipid research and supports their activities by providing shared core resources, funding for pilot/feasibility studies and a common intellectual environment.
    **Activities & Services**
    Cores
        Translational Biomarker Analytical Core
            Cytometry and Cell Sorting Core
            Advanced Tissue Pathology and Imaging Core
            Mouse Metabolic Function and Phenotyping Core
        Pilot & Feasibility Program
****Indiana University****
**Research Aims:** The mission of the new, integrated Indiana Diabetes Research Center (IDRC) is to foster knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders, and their complications.
    **Activities & Services**
    Cores
        Islet and Physiology Core
            Microscopy Core
            Swine Core
            Translation Core
        Pilot & Feasibility Program**Joslin Diabetes Center - Harvard Medical School**
**Research Aims:**The mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.
    **Activities & Services**Cores
        Animal Physiology Core
            Flow Cytometry Core
            Molecular Phenotyping and Genotyping Core
            Clinical Translational Core
            Genome Editing Core
        Pilot & Feasibility Program
        Enhance research into the pathogenesis, treatments and potential cures for all types of diabetes and their complications more generally.
****
**North Carolina Diabetes Research Center**
**Research Aims:**The North Carolina Diabetes Research Center supports an interactive diabetes research community across four premiere research institutions in North Carolina: Duke University (Duke) The University of North Carolina at Chapel Hill (UNC), Wake Forest School of Medicine (WF), and North Carolina A&T (NC A&T).
    **Activities & Services** 
    Cores
        Genomics and Proteomics
            Metabolomics
        Pilot & Feasibility Program
        The North Carolina Diabetes Research Center Pilot & Feasibility Program will encourage use of regional Cores, bring to the field new investigators and young scientists, and draw those not previously working in the field.
****Stanford University****
**Research Aims:** The mission of the Stanford Diabetes Research Center is to support basic and clinical research to discover, apply and translate science about diabetes and it complications, to improve health and wellness.
    **Activities & Services**
    Cores
        Diabetes Immune Monitoring Core
            Clinical and Translational Core
            Islet Research Core
            Diabetes Genomics and Analysis Core
        Pilot & Feasibility Program****University of Alabama at Birmingham****
**Research Aims:**The center focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.  The DRC supports the areas of animal physiology, human biology and intervention and translational research.
    **Activities & Services**
    Cores
        Animal Physiology Core (APC)
            Human Physiology Core (HPC)
            Interventions and Translation Core (ITC)
        Pilot & Feasibility Program
        The P&F program will foster new research programs in diabetes and support a broad base of basic, clinical, translational, and prevention and control projects.
**UCSD-UCLA**
**Research Aims:**The center fosters research in the prevention and treatment of diabetes and endocrine diseases and their complications and ultimately to improves the lives of endocrine patients.
    **Activities & Services**
    Cores
        Transgenic and Knockout Mouse
            Metabolic and Molecular Physiology
            Transcriptional Genomics
            Epigenetic and Genomics
            Human Genetics
        Pilot & Feasibility Program
        The DRC P&F mechanism will fund innovative new projects that will explore the feasibility of novel testable concepts and enhance the endocrine/diabetes research scope within the institutions.****University of Chicago****
**Research Aims:**The University of Chicago Diabetes Research and Training Center promotes multidisciplinary research in diabetes.
    **Activities & Services**
    Cores
        Cell Biology Core
            Genetics and Genomics Core
            Physiology Core
        Pilot & Feasibility Program
        Supports new investigators in diabetes research as well as established investigators in other fields to conduct novel research related to diabetes.
**University of Colorado**
**Research Aims:**
    The University of Colorado Denver (UC Denver) is world renowned for basic, translational, and clinical diabetes research and treatment of both Type 1 and Type 2 diabetes (T1D and T2D), and their related complications.
    **Activities & Services**
    Cores
        Clinical Resource
            Tissue Procurement and Processing
            Cell and Tissue Analysis
            Disease Modeling
        Pilot & Feasibility Program
        The UC Denver Pilot & Feasibility Program will recruit young faculty into diabetes and diabetes-related research and encourage established investigators from other fields to enter the diabetes field.****
**University of Michigan**
**Research Aims:**The goal of the MDRC is to establish, promote, and enhance multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders.
    **Activities & Services**
    Cores
        Animal Studies Core
            Clinical Core
            Molecular Genetics Core
            Microscopy, Imaging, and Cellular Physiology Core
        Pilot & Feasibility Program
        Proposals must focus on type 2 translational research in diabetes: the translation of research advances into widespread clinical or community practice. The research may focus on the identification of barriers to widespread adoption of new science and the testing of interventions to overcome those barriers.**University of Pennsylvania**
**Research Aims:**Supports research in diabetes and endocrinology via Scientific Cores, a Pilot and Feasibility Grant Program, and a series of seminars, retreats and other activities that facilitate communication and collaboration of DRC investigators while keeping them abreast of the latest discoveries in diabetes and endocrinology.
    **Activities & Services**
    Cores
        Functional Genomics Core
            Metabolomics Core
            Islet Cell Biology Core
            Mouse Phenotyping, Physiology and Metabolism Core
            Radioimmunoassy/Biomarker Core
            Transgenic and Chimeric Mouse Core
            Viral Vector Core
        Pilot & Feasibility Program
        The P&F program is particularly directed at new investigators and established investigators new to diabetes research. Established diabetes investigators pursuing high impact/high risk projects or projects that are a significant departure from their usual work are also eligible for support under the DRC P&F program. Applications are welcome from basic, clinical and translational investigators.**University of Washington**
**Research Aims:**Facilitating and enhancing diabetes research to find a cure to diabetes.
    **Activities & Services**
    Cores
        Cell Function Analysis Core
            Cellular and Molecular Imaging Core
            Quantitative and Functional Proteomics Core
            Vector and Transgenic Mouse Core
        Pilot & Feasibility Program
        Intended to develop new research in the area of diabetes and its complications at the University of Washington.**Washington University**
**Research Aims:**Our long-term goal is the development of new preventive strategies and therapies aimed at improving the lives of Americans with diabetes and those at risk for diabetes and related metabolic disorders.
    **Activities & Services**
    Cores
        Diabetes Models Phenotyping Core
            Transgenic & ES Cell Core
            Translational Diagnostics Core
            Cell and Tissue Imaging Core
            Metabolic Tissue Function Core
            Metabolomics Core
        Pilot & Feasibility Program****Vanderbilt Diabetes Research and Training Center****
**Research Aims:**The Vanderbilt Diabetes Research and Training Center (DRTC) is a NIH-sponsored Diabetes Center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes. Our investigators conduct basic, clinical, and translational research on the etiology, prevention, treatment, and complications of diabetes and obesity. The DRTC supports core facilities that enhance diabetes-related research and organizes an Enrichment Program of seminars and small groups that create a dynamic and inclusive environment for the training of the next generation of scientists. We invite you to collaborate or interact with us as we work to reduce the burden of diabetes.
    **Activities & Services**
    Cores
        Hormone Assay & Analytical Services Core
            Animal Metabolic Physiology Core
            Human Metabolic Physiology and Genomics Core
            Islet and Pancreas Analysis
        Pilot & Feasibility Program**Yale University**
**Research Aims:**The scope of the research activities of the membership is very broad, ranging from basic molecular biology to whole body clinical physiology in patients with diabetes.
    **Activities & Services**
    Cores
        Cell Biology Core
            Clinical Metabolism Core
            Diabetes Translational Core
            Physiology Core
            Molecular Genetics Core
        Pilot & Feasibility Program
        Priority will be given to new collaborative investigations.Centers for Diabetes Translation Research (CDTRs)
The CDTR  mission is to improve translation of research related to diabetes prevention, treatment, and health equity by supporting research across the T2-T4 translational spectrum (e.g., moving from efficacy to testing effectiveness in real world practice and communities and dissemination and implementation science). CDTRs are intended to enhance the efficiency, productivity, and multidisciplinary and multisectoral nature of diabetes translation research through shared access to specialized technical expertise and resources.  CDTRs' expertise includes intervention adaptation and refinement, development of measures, techniques, processes, methods, and practices related to diabetes translation research. These innovative Centers along with their diverse partnership models provide the infrastructure needed to advance translational research in health disparities and health equity by providing core services and consultation at their local institutions, as well as resources regionally and nationally.
**Einstein College of Medicine**
**Research Aims:**The aim of the New York Regional Center for Diabetes Translation Research is to increase collaboration and enhance communication among investigators from multiple institutions and diverse disciplines. There is a focus on the following unifying themes – health equity and addressing differences in population health status that can be traced to unequal economic and social conditions; and using a biopsychosocial approach to integrate diabetes and obesity translational research through consideration of biological, psychological, and social determinants of health and disease.
    **Activities & Services**
    Cores
        Behavioral Science and Technology Core (BSTC)
            Life Course Methodology Core
            Population Health and Health Systems (PHHS) Core
            National Core: Latino Network for Diabetes Translational Research
        Enrichment Program
        Pilot & Feasibility Program**Emory University**
**Research Aims:**The Georgia Center for Diabetes Translation Research (GCDTR) focuses on advancing the science regarding the reach, effectiveness, adoption, and sustainability of technological, behavioral, pharmacological diabetes prevention and management advances. To do this, GCDTR leverages design and evaluation expertise; careful application of socioecological models, behavioral sciences, and community-engaged participatory research that can improve engagement with clinical, policy, and community stakeholders; and established and emerging technologies to advance translation research for health equity.
    **Activities & Services**
    Cores
        Design and Evaluation for Equity Core
            Socioecological and Behavioral Science for Equity Core
            Regional Core: Technologies Advancing Translation and Equity Core
        Enrichment Program
        Pilot & Feasibility Program**Kaiser Foundation Research Institute**
**Research Aims:**The Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research (DREAMS-CDTR) aims to advance health equity science through the development and translation of: 1) innovations and structural changes to healthcare delivery systems that substantively reduce health inequalities, and 2) innovative, scalable interventions to alter the socioenvironmental drivers of the Type 2 Diabetes epidemic and associated disparities. Focusing on the northern California and Central Valley regions of California, the DREAMS-CDTR will provide research resources for investigators to conduct clinical research and interventions designed to inform practice and policy change at the health system, community and policy levels. The DREAMS-CDTR (formerly Health Delivery Systems) brings together translational science core faculty who have expertise in diverse, multi-level areas including: food insecurity, medication adherence, health communication, health IT, social policy, and cost effectiveness analysis. DREAMS-CDTR involves five regional academic sites with a range of public and non-profit health systems that serve large and diverse populations: Kaiser Permanente Northern California’s Division of Research, Stanford University and the University of California at San Francisco, Merced and Davis.
    **Activities & Services**
    Cores
        Health Equity and Action Translational (HEAT) Core
            Methods and Data Integration (MDI) Core
            National Core: National Diabetes Policy Resource (DPR) Core
        Enrichment Program
        Pilot & Feasibility Program**University of Chicago** 
**Research Aims:**The aims of the Chicago Center for Diabetes Translation Research are to increase the impact of rigorous diabetes translation research to reduce disparities in Chicago and the nation by organizing partnerships across academic institutions and stakeholder groups into working groups that include: Clinician-Patient Relationship and Shared Decision Making, Social Determinants of Health, Diabetes Prevention, Diabetes Modeling, Organization and Financing of Care, Diabetes and Aging; and to attract and support diverse investigators who are new to the area of diabetes translation research by providing education, training, mentoring, support for community and stakeholder engagement, pilot and feasibility seed grants, and access to critical translational research core resources. This CDTR combines the complementary strengths of the University of Chicago and Northwestern University, as well as numerous partners and stakeholders, into a city-wide center to amplify the center’s impact on Chicago, the Midwest region, and nation.
    **Activities & Services**
    Cores
        Research Design, Data, and Analytics Core
            Community Engagement and Health Equity Core
            National Core: Accelerating Health Equity and Eliminating Diabetes Disparities in Community Health Centers (AHEAD-CHC)
        Enrichment Program
        Pilot & Feasibility Program**University of Colorado**
**Research Aims:**The aims of the Center for American Indian and Alaska Native Diabetes Translation Research (CAIANDTR) is to translate research of proven efficacy into practice in both clinical and community settings, with the goal of improving the diabetes-related health of Native people. CAIANDTR builds directly upon our decade-long coordination of the Indian Health Service’s Special Diabetes Program for Indians (SDPI). CAIANDTR provides resources locally, regionally, and nationally in areas relevant to the NIDDK's translation research agenda. Our work is specific to AI/ANs, but is generalizable to other segments of the population. CAIANDTR's specific aims are to: (1) Provide an administrative structure that promotes excellence in translation research and research capacity-building specific to improving diabetes-related health among AI/ANs; (2) Evaluate the impact of training, technical assistance, and consultation activities on the capacity of other investigators to pursue scientifically meritorious diabetes translation research specific to AI/ANs; and (3) Expand training, technical assistance, and consultation activities, delivered through a Research Base of funded faculty, whose research either targets diabetes or is translational in nature with clear potential for application to diabetes.****
    **Activities & Services**
    Cores
        Translational Research Core
            Community Outreach and Engagement Core
            Health Literacy
            National Resource Core (NRC)
        Enrichment Program
        Pilot & Feasibility Program
        Research focuses on small scale research projects that explore the extension of diabetes prevention and treatment research – with special emphasis on reducing risk as well as enhancing clinical outcomes – to American Indians and Alaska Natives.  There is particular interest in stimulating work that considers the relevance of recent discoveries for application within Native communities.**University of Michigan**
**Research Aims:**The goal of the Michigan Center for Diabetes Translational Research (MCDTR) is to advance research along the continuum of diabetes T2-T4 translational research to prevent diabetes and enhance health and wellbeing of people with diabetes, with a specific emphasis on novel approaches to improve health equity. This goal is accomplished by promoting research that supports rapid dissemination, implementation, and sustained use of effective interventions, programs, and policies. The MCDTR fosters and helps sustain multidisciplinary, novel, and cross-sectoral collaborations, including work with multiple health and social service organizations, where appropriate, to advance emerging scientific areas of translational research and health equity.  By attracting, retaining, developing, and supporting early stage and other researchers to conduct research that translates scientific discoveries from bedside to practice and to the community, improvements in diabetes prevention, treatment, population health, and health equity are achievable.
    **Activities & Services**
    Cores
        Evaluation Methods and Intervention Strategies Core
            Addressing Social and Behavioral Determinants of Health Core
            National Core: Leveraging Community, Peer, and Family Support Core
        Enrichment Program
        Pilot & Feasibility Program**Washington University at St. Louis**
**Research Aims:**The Washington University Center for Diabetes Translation Research (WU-CDTR) aims to advance a rigorous, scientific evidence base to inform the dissemination, implementation, and sustainability of efficacious interventions for populations at risk for diabetes disparities. The Center is guided by a strategic vision in which a health equity lens is the foundation for transformative diabetes research translated into action and impact. This equity-driven vision informs our Center mission to be the nexus for transdisciplinary team science in advancing the conduct of the next generation of diabetes translation research. The WU-CDTR is a collaboration between Washington University in St. Louis, the Council on Black Health, housed at Drexel University, and the University of Missouri, Columbia.
    **Activities & Services**
    Cores
        Dissemination and Implementation in Diabetes Research
            Health Communication and Health Literacy
            Policy and Systems Science Analysis
            Regional Core: Health Informatics in Diabetes Research
            National Core: Solutions to Diabetes in Black Americans
        Enrichment Program
        Pilot and Feasibility Program
Related Links
Digestive Diseases Research Core Centers
    Diabetic Complications Consortium
    Medical Student Research Program in Diabetes
    Nutrition Obesity Research Centers
    Type 1 Diabetes Special Statutory Funding Program
    NIDDK Active Trials in Diabetes and Endocrine Disease
    View related clinical trials from ClinicalTrials.gov.
    NIH Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

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        Last Reviewed April 2023 Contact Us
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