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Research Programs & Contacts
-  Diversity ProgramsShow child pages    -  Diversity Supplement Program 
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  -  Travel & Scholarship Awards 
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  -  Investigator Award to Support Mentoring of Early Career Researchers from Diverse Backgrounds 
  -  NIDDK Partnerships with Professional Societies 
  -  Helping to Accelerate Research Potential (HARP) 
-  Liver Clinical Research & Epidemiology 
-  Small Business Programs 
-  Translational ResearchShow child pages    -  Disease Biology 
  -  Target Identification 
  -  Assay Development 
  -  Screening 
  -  Hit to Lead 
  -  Lead Optimization 
  -  Pre-Clinical Development 
  -  Clinical Development 

# Liver Clinical Research & Epidemiology

        Patient-oriented clinical research and epidemiological research in hepatotoxicity due to drugs and dietary supplements.    

The Liver Clinical Research and Epidemiology program supports patient-oriented clinical research in liver diseases.  Work in the program examines a wide range of experimental interventions or diagnostics with direct impact on liver disease diagnosis or pathology endpoints.

The program emphasizes research on common and rare liver diseases and supports large clinical research networks. Current and past clinical research networks supported by this program have included: NASH Clinical Research Network, Adult-to-Adult Living Donor Liver Transplantation Cohort Study, Adult Acute Liver Failure Study Group, Pediatric Acute Liver Failure, Drug-Induced Liver Injury Network, Childhood Liver Disease Research  Network, Liver Cirrhosis Network, Improving Medication Adherence in Children who had a Liver Transplant Study, Pediatric Acute Liver Failure Immune Response Network, Hepatitis B Research Network, Hepatitis C Antiviral Long-term Treatment against Cirrhosis, and Peds C.

## NIDDK Program Staff

          -  Edward Doo, M.D.                     Fatty Liver Disease; Genetic Liver Disease; HIV and Liver; Pediatric Liver Disease; Viral Hepatitis and Infectious Diseases                
          -  Jose Serrano, M.D., Ph.D.                     Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis; Drug Induced Liver Injury; Clinical Research on GI Diseases                
          -  Averell H. Sherker, M.D., FRCPC                     Autoimmune Liver Disease; Acute Liver Failure; Complications of Chronic Liver Disease; Gallbladder and Biliary Diseases; Liver Bioengineering and Biotechnology; Liver Cancer; Liver Transplantation                
          -  Aynur Unalp-Arida, M.D., M.Sc., Ph.D.                     Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition                

## Recent Funding Opportunities

View More Recent Funding Opportunities
-  Posted:4/2/2024PAR-24-206  Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)  Summary 
-  Posted:3/27/2024NOT-OD-24-078  Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research  Summary 
-  Posted:3/26/2024NOT-OD-24-079  Notice of Special Interest: Womens Health Research  Summary 
-  Posted:3/26/2024RFA-NS-25-012  HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)  Summary 
-  Posted:3/18/2024PAR-24-162  Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)  Summary 

View More Recent Funding Opportunities

## Related Links

-    Human Subjects Research 
-    NIDDK Active Trials in Liver Disease  
View related clinical trials from ClinicalTrials.gov.
 
-    NIH Study Sections  
    Study sections conduct initial peer review of applications in a designated scientific area.    Visit the NIH’s Center for Scientific Review website to search for study sections.    
 
-   LiverTox  
This online resource provides information on drug-induced liver injury resulting from prescription medications, over-the-counter drugs, and complementary and alternative medicines such as herbals and dietary supplements.
 

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## Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

-  Ancillary Studies to Major Ongoing Clinical Studies  to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.    
-  NIDDK Central Repository  for access to clinical resources including data and biospecimens from NIDDK-funded studies.    
-  NIDDK Information Network (dkNET)  for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.    

## Additional Research Programs

### *Research*Training

NIDDK supports the training and career development of medical and graduate students, postdoctoralfellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs

### Diversity

#### Diversity Programs

The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs

### Small Business

#### Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business TechnologyTransfer (STTR) programs.These programs support innovative research conducted by small businesses that has the potential forcommercialization.
Learn about NIDDK Small Business Programs

### Human Subjects*Research*

#### Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research

### Translational*Research*

NIDDK provides funding opportunities and resources to encourage translation of basic discoveriesinto novel therapeutics.
Learn about NIDDK Translational Research Opportunities

## Meetings & Workshops

                                dkNET                            
                                                                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.                                                                                                                    

                                NIH Regional Seminars on Program Funding and Grants Administration                            
                                                                                Providing education and training for the next generation of biomedical and behavioral scientist                                                                                                                    

                                NIH Small Business (SBIR & STTR) Engage & Connect                            
                                                                                Stay informed about the latest events, or connect through social media.                                                                                                                    

                                View all Meetings & Workshops                            

View all Meetings & Workshops

          -    NIH Common Fund  
Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
 
          -    Planning to Apply? Register Early  
Registration is required at eRA Commons and grants.gov and can take 4 weeks.