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                    Phoenix Epidemiology & Clinical Research Branch
                    Join a Clinical Trial in Phoenix
    Phoenix Epidemiology & Clinical Research Branch
            Chief:         Clifton Bogardus III, M.D.
        
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        Join a Clinical Trial in Phoenix
    Join a Clinical Trial in Phoenix
    NIDDK’s Phoenix Epidemiology and Clinical Research Branch conducts clinical trials on obesity and diabetes in Phoenix, Arizona. Clinical trials look at new ways to prevent, detect, or treat disease and improve quality of life.  If you are interested in participating in a trial in Phoenix, contact
**Phoenix Recruitment Office****Hours**: 7:00 a.m. to 3:30 p.m. Phoenix, AZ Time, Monday-Friday**Email**: niddkphxcontact@mail.nih.gov**Phone**: 602-200-5310
Clinical Trials That Are Currently Recruiting

Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
The purpose of this study is to investigate how eating diets that vary in calories affect your metabolism. This will help us understand how the number of calories we eat impacts our energy and metabolism.            More
            **What is required:**
34-day inpatient stay on research unit
Psychological questionnaires and behavioral tests
Physical exam, body fat, and metabolism measurement
Oral Glucose Tolerance Test to determine diabetes
Collection of blood and urine samples
Different diets provided during stay
    Compensation is provided**Who can participate:**
Adult males and females, aged 18-60 years old
Non-diabetic
Healthy as determined by exam and medical history
Not pregnant or breast feeding
Not taking medications that affect metabolism or appetites
    Drug and nicotine screen negative**Interested in participating?****Email:** niddkphxcontact@mail.nih.gov**Phone:** 602-200-5310

COVID-19 and Its Impact on Food, Eating Behaviors, and Weight
This research study examines the relationship between specific COVID-19 related stressors and self-rated eating habits among participants to help understand the effects of the pandemic on our eating behaviors and weight. It is being conducted by Dr. Marci Gluck and her team at NIH/NIDDK.            More
            **What is required:**
Completion of a one-time, online study consent and 20-minute survey
    Option to participate in a 2 minute daily at-home survey for one week
    Option to participate in a monthly online follow-up survey**Who can participate:**
Adults 18 years and older
    Have access to a computer and/or internet to complete online survey
    English-speaking**Interested in participating?****Online:** https://redcap.link/nihcovidstudy**Email:** niddkphxcontact@mail.nih.gov**Phone:** 602-200-5310

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake
This study will investigate if we can identify how much sugar people drink in the form of sweetened soda. It will also help us develop ways to identify the kinds of foods people eat in their everyday lives.            More
            **What is required:**
Inpatient stay of 13 weeks
    The Study consists of:
    Hair sampling
        Several questionnaires
        Computerized psychological and behavior tests
        Computerized psychological and behavior tests
        DXA scan for measurement of body fat
        2 sets of fat biopsies
        3 overnight stays in a metabolic chamber
        Stool and urine collection
        Blood draws
        Oral Glucose Tolerance Test
    Participants are asked to eat a specific diet prepared for them during their entire stay
    No follow up visits
    Compensation is provided**Who can participate:**
18-65 years old
    In generally good health
    Not pregnant or breast feeding
    Not taking any chronic medications
    Drug-screen negative
    Non-smoker**Interested in participating?****Online:** https://redcap.link/nihcovidstudy**Email:** niddkphxcontact@mail.nih.gov**Phone:** 602-200-5310

Transcranial Direct Current Stimulation (tDCS) Protocol
This study will see whether external stimulation to the brain will lead to changes in eating patterns and weight. Previous research has shown that an area of the brain responsible for the feeling of hunger and fullness, known as the dorsolateral prefrontal cortex, is less active in people with obesity compared to lean people after a meal.            More
            **What is required:**
One outpatient screening visit (2 hours) to ensure you meet study participation criteria
    One outpatient baseline and one follow-up visit (5-6 hours each) with:
    computer tests and questionnaires to determine your eating habits, mood, and levels of awareness/thinking
        a test to measure your body composition
        a weight loss and diet counseling session
    four functional MRI scans performed on two different days at a local hospital to see if brain activity is stimulated by tDCS
    27 morning outpatient visits (lasting approximately 1 hour), 3 days a week for 9 weeks for brain stimulation sessions
    You will be asked to eat a 25% reduced calorie diet during that 9-week period (outlined during the counseling session)
    Compensation is provided**Who can participate:**
18-60 years old
    In generally good health
    Considered overweight with a BMI greater than 25 kg/m2
    Right-handed**Interested in participating?****Email:** niddkphxcontact@mail.nih.gov**Phone:** 602-200-5310

The Food Intake Phenotype
This study investigates eating behavior and food preferences. This is to better understand risk
factors associated with obesity and possibly develop strategies to assist people in losing weight.            More
            **What is required:**
Inpatient stay of about 10 days on research unit
    The study consists of:
    several questionnaires
        computerized psychological behavior tests
        oral glucose tolerance test to determine if you have diabetes
        DXA scan for measurement of body fat
        2 sets of fat biopsies
        overnight stay in a metabolic chamber
        urine collection and blood draws
    Participants eat a diet that is provided for them during their stay
    No follow up visits
    Compensation is provided**Who can participate:**
18-65 years old
    Non-diabetic
    Healthy as determined by exam and medical history
    Not pregnant or breast feeding
    Not taking medications that affect metabolism
    Drug-screen and nicotine screen negative**Interested in participating?****Email:** niddkphxcontact@mail.nih.gov**Phone:** 602-200-5310

Changes in Metabolism and Eating Habits
This study investigates the amount of food a person eats when the body’s metabolic rate is changed. Investigators want to see how much food is eaten when the body’s temperature is cooled. The study will also see if not eating for an entire day will change someone’s eating habits the next day.            More
            **What is required:**
23-day inpatient stay on research unit
    Psychological questionnaires and behavioral tests
    Physical exam, body fat, and metabolism measurement
    Oral Glucose Tolerance Test to screen for diabetes
    Collection of blood and urine samples
    Diet provided during stay
    Two 1-day follow up visits 6 months and 1 year after inpatient stay
    Compensation is provided**Who can participate:**
18-55-year-old males and premenopausal females
    Non-diabetic
    Healthy as determined by exam and medical history
    Not pregnant or breast feeding
    Not taking medications that affect metabolism or appetite
    Drug and nicotine screen negative**Interested in participating?****Email:** niddkphxcontact@mail.nih.gov**Phone:** 602-200-5310
        Last Reviewed November 2023 Contact Us
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