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                    Research & Funding
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                    Motility & Functional Gastrointestinal Disorders

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        Disease Biology
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                Clinical DevelopmentMotility & Functional Gastrointestinal Disorders
    Research on gastrointestinal motility and functional gastrointestinal disorders.
    The Motility and Functional Gastrointestinal Disorders program supports basic, clinical, and translational research on aspects of gut physiology regulating motility, including research on the structure of gastrointestinal muscles and the biochemistry of contractile processes and mechano-chemical energy conversion relations between metabolism and contractility in smooth muscle; the basic biology of gut smooth muscle and the role of the nervous system in digestion and factors that affect gut motility; and the effect of gastrointestinal diseases and disorders on gastrointestinal motility.  The program also supports clinical trials to test new treatments for functional gastrointestinal disorders and epidemiology studies to address risk factors for disease occurrence, prognosis, or natural history.  Particular clinical areas of interest include irritable bowel syndrome, gastroparesis, functional dyspepsia, colonic diverticular disease, swallowing disorders, and gastroesophageal reflux.
    NIDDK Program Staff
        Patricia Greenwel, Ph.D.
                    Basic and Translational Gastrointestinal Developmental Biology, Stem Cell Biology, Neurogenesis, Epithelial Cell Biology, Lymphatics, and Pathogenesis of HIV-Related Disease
                Terez Shea-Donohue, Ph.D.
                    Basic and Translational Neurogastroenterology, Gastrointestinal Motility, Gastrointestinal Barrier Function, Mucosal Immunology and Inflammation
Recent Funding Opportunities
                    View More Recent Funding Opportunities
        Posted:
                                4/10/2024
                            PA-24-184
                    Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Required)
                    
                    Summary
                Posted:
                                4/9/2024
                            PA-24-185
                    Mentored Patient-Oriented Research Career Development Award (Parent K23  Independent Clinical Trial Not Allowed)
                    
                    Summary
                Posted:
                                4/2/2024
                            PAR-24-206
                    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
                    
                    Summary
                Posted:
                                3/27/2024
                            NOT-OD-24-078
                    Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research
                    
                    Summary
                Posted:
                                3/26/2024
                            RFA-NS-25-012
                    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
                    
                    SummaryView More Recent Funding Opportunities
Related Links
NIDDK Active Trials in Gastrointestinal Disease
    View related clinical trials from ClinicalTrials.gov.
    NIH Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area.
    Visit the NIH’s Center for Scientific Review website to search for study sections.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

Meetings & Workshops
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                            dkNET
                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
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    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
    Planning to Apply? Register Early
    Registration is required at eRA Commons and grants.gov and can take 4 weeks.
        Last Reviewed October 2023 Contact Us
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