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        Disease Biology
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                Pre-Clinical Development
                Clinical DevelopmentObesity Treatment & Prevention
    Behavioral, pharmacological and surgical approaches; research evaluating environmental, policy, and population-based prevention strategies.
    The Obesity Treatment and Prevention program supports research on the prevention and treatment of overweight and obesity across the lifespan.  Research focuses on critical periods for excess weight gain or high-risk populations.
Prevention research includes studies of treatment approaches to stop the initial development of overweight/obesity or to prevent additional weight or fat gain in people who are already overweight or have obesity. These approaches include behavioral, lifestyle, or environmental interventions to improve diet, decrease sedentary behavior, and increase physical activity.  Treatment research focuses on clinical trials that evaluate different approaches to losing weight, improving BMI percentile in growing children, or maintaining weight loss.  These interventions involve behavioral, pharmacologic, and surgical approaches.
Research to understand and address psychosocial risk factors related to weight management is also supported.  For example, obesity research addressing binge eating, stress, impulsivity, and the influence of social networks might be supported if the primary aim is to improve weight management.
The program also promotes research testing environmental, policy-based, and population-based approaches to the prevention and treatment of obesity, including studies evaluating the impact of programs or policies on diet, physical activity, or obesity development.
    NIDDK Program Staff
        Mary Evans, Ph.D.
                    Multi-center Clinical Studies in Nutrition & Obesity; Nutrition Obesity Research Centers; Diet & Physical Activity Assessment Methodology
                Craig Hales, M.D, M.P.H, M.S.
                    Clinical Obesity Prevention and Treatment
                Stavroula K. Osganian, M.D., Sc.D., M.P.H.
                    Pediatric Clinical Obesity
Recent Funding Opportunities
                    View More Recent Funding Opportunities
        Posted:
                                4/2/2024
                            PAR-24-206
                    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
                    
                    Summary
                Posted:
                                3/27/2024
                            NOT-OD-24-078
                    Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research
                    
                    Summary
                Posted:
                                3/26/2024
                            NOT-OD-24-079
                    Notice of Special Interest: Womens Health Research
                    
                    Summary
                Posted:
                                3/26/2024
                            RFA-NS-25-012
                    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
                    
                    Summary
                Posted:
                                3/18/2024
                            PAR-24-162
                    Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
                    
                    SummaryView More Recent Funding Opportunities
Related Links
NIDDK Active Trials in Obesity and Nutrition
    View related clinical trials from ClinicalTrials.gov.
    NIH Study Sections
    Study sections conduct initial peer review of applications in a designated scientific area.
    Visit the NIH’s Center for Scientific Review website to search for study sections.Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
    NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
    NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.Additional Research Programs
ResearchTraining
NIDDK supports the training and career development of medical and graduate students, postdoctoral
fellows, and physician scientists through institutional and individual grants.
Learn about NIDDK Research Training Programs
Diversity
Diversity Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.
Learn about NIDDK Diversity Programs
Small Business
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology
Transfer (STTR) programs.
These programs support innovative research conducted by small businesses that has the potential for
commercialization.
Learn about NIDDK Small Business Programs
Human SubjectsResearch
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.
Learn about Human Subjects Research
TranslationalResearch
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries
into novel therapeutics.
Learn about NIDDK Translational Research Opportunities

Meetings & Workshops
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                            dkNET
                                Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
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                            NIH Regional Seminars on Program Funding and Grants Administration
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    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
    Planning to Apply? Register Early
    Registration is required at eRA Commons and grants.gov and can take 4 weeks.
        Last Reviewed October 2023 Contact Us
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