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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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          CLEARAcute Respiratory Distress SyndromeAlpha-1 Antitrypsin DeficiencyAnemiaAngina (Chest Pain)Aortic AneurysmAplastic AnemiaArrhythmiasAsthmaAtherosclerosisAtrial FibrillationBleeding DisordersBlood CholesterolBlood Clotting DisordersBronchiectasisBronchitisCardiac ArrestCardiac CatheterizationCardiogenic ShockCardiomyopathyChildhood ObesityCircadian Rhythm DisordersConduction DisordersCongenital Heart DefectsCOPDCoronary Artery Bypass GraftingCoronary Heart DiseaseCystic FibrosisDeep Vein Thrombosis (DVT)DefibrillatorsGet Regular Physical ActivityHeart-Healthy LivingHeart AttackHeart FailureHeart Inflammation(-)
Heart SurgeryHeart TestsHeart TransplantHeart TreatmentsHeart Valve DiseasesHemolytic AnemiaHigh Blood PressureHigh Blood TriglyceridesHow Sleep WorksHow the Heart WorksHow the Lungs WorkIdiopathic Pulmonary FibrosisInterstitial Lung DiseasesLAMLong QT SyndromeLow Blood PressureLung Disease TreatmentsMarfan SyndromeNarcolepsyNewborn Breathing ConditionsOverweight and ObesityPacemakersPeripheral Artery DiseasePhysical Activity and Your HeartPleural DisordersPolycythemia VeraPrimary Ciliary DyskinesiaPulmonary HypertensionPulmonary RehabilitationRespiratory FailureSarcoidosisSickle Cell DiseaseSleep ApneaSleep Deprivation and DeficiencySleep StudiesSmoking and Your HeartStrokeTests for Lung DiseaseThalassemiaThe LungsTranscatheter Aortic Valve Replacement (TAVR)Treatments for Blood DisordersVasculitisVenous ThromboembolismVentilator/Ventilator SupportWhat Is Physical Activity?Women and Heart Disease

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Clear AllHeart Surgery
Showing 1 - 4 out of 4 results
      
      SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery
      Recruiting
                          Tennessee
        The goal of this mechanistic clinical trial is to learn about the effects of medications called soluble guanylyl cyclase stimulators on vascular function and markers of kidney and brain injury in patients having heart surgery. This will provide important information to determine the underlying reasons that patients have some kidney and brain function problems after having heart surgery.
      Heart Surgery
                          Adult, Older Adult
    TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
      Recruiting
                          Massachusetts
        Are you scheduled for open-heart surgery for your aortic valve? This study aims to look at changes in inflammation and gene activity while surgery patients are on a heart-lung bypass machine. To participate in this study, you must be at least 20 years old and be scheduled for aortic valve surgery, either with or without coronary artery bypass grafting (CABG). This study is located in Boston, Massachusetts.
      Coronary Artery Bypass Grafting
              Heart Surgery
              Heart Valve Diseases
                          Adult, Older Adult
    Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)
      Recruiting
                          Multiple Locations
        Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery?
                    Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
      Arrhythmias
              Atrial Fibrillation
              Coronary Artery Bypass Grafting
              Stroke
              Heart Surgery
                          Adult, Older Adult
    Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
      Recruiting
                          California
        Are you planning to have coronary artery bypass grafting (CABG) surgery to treat your heart disease? This study aims to use computed tomography (CT) imaging to help doctors and their patients make better decisions about heart surgery. To participate in this study, you must be at least 40 years old and be scheduled for a CABG. This study is located in Palo Alto and San Diego, California
      Atherosclerosis
              Heart Surgery
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