**Exhibit 24.1**

**Power of Attorney**

**Know AllPersons By These Presents**, that each person whose signatureappears below constitutes and appoints Gordon H. Link, Jr., Kai Larson,and Matthew Majoros, and each or any one of them, his true and lawful attorney-in-factand agent, with full power of substitution and resubstitution, for him and inhis name, place and stead, in any and all capacities, to (i) sign theannual report on Form 10-K filed by Tapestry Pharmaceuticals, Inc.(the “Company”) for the fiscal year ended December 27, 2006 and(ii) sign any and all amendments to the Form 10-K, and to file thesame, with all exhibits thereto, and other documents in connection therewith,with the Securities and Exchange Commission, granting unto said attorneys-in-factand agents, and each of them, full power and authority to do andperform each and every act and thing requisite and necessary to be done inconnection therewith, as fully to all intents and purposes as he might or coulddo in person, hereby ratifying and confirming all that said attorneys-in-factand agents, or any of them, or their or his substitutes or substitute,may lawfully do or cause to be done by virtue hereof.
| Signature                          | ** ** | **Title**                                               | ** ** | **Date**      |
|------------------------------------|------------|---------------------------------------------------------|------------|---------------|
| ** **                         | ** ** | ** **                                              | ** ** | ** **    |
| /s/ Leonard P.  Shaykin            |       |                                                    |       |          |
| Leonard P.  Shaykin                |       | Chairman of the Board Chief Executive Officer  Director |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ Stephen K.  Carter             |       |                                                    |       |          |
| Stephen K.  Carter, M.D.           |       | Director                                                |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ George Gould                   |       |                                                    |       |          |
| George  Gould, Esq.           |       | Director                                                |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ Arthur Hull  Hayes             |       |                                                    |       |          |
| Arthur Hull  Hayes, Jr., M.D. |       | Director                                                |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ Elliot M.  Maza                |       |                                                    |       |          |
| Elliot M.  Maza, Esq.         |       | Director                                                |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ Richard N.  Perle              |       |                                                    |       |          |
| The Honorable  Richard N. Perle    |       | Director                                                |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ Patricia A.  Pilia             |       |                                                    |       |          |
| Patricia A.  Pilia, Ph.D.          |       | Director                                                |       | March 6, 2007 |
|                               |       |                                                    |       |          |
| /s/ Robert E.  Pollack             |       |                                                    |       |          |
| Robert E.  Pollack, Ph.D.          |       | Director                                                |       | March 6, 2007 |

 

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