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          About NIAMS
          Pankaj Sharma, Ph.D.





Pankaj Sharma, Ph.D.


Research Fellow
    Pediatric Translational Research Branch Image
              Photo of Pankaj Sharma 
            Contact Information

                                                  301-443-8935
                
                                                9000 Rockville Pike
                  
            10 Center Drive
      
                  
            Building 10, Room 12S261
      
                                   Bethesda MD 20892
                
                                                pankaj.sharma2@nih.gov 
                Summary
          Pankaj Sharma, Ph.D., is a Postdoctoral Fellow in the Pediatric Translational Research Branch at the NIAMS. His research focuses on identifying genetic variations and determining molecular mechanisms associated with human diseases.
        
                  Research Statement
          
            The goal of Dr. Sharma's research is to elucidate the cellular and molecular mechanisms underlying the pathogenesis of spondyloarthritis (SpA) in search of effective therapies. This clinically heterogeneous group of disorders affects an estimated 1% of the population worldwide. Evidence suggests that genetic factors are significant determinants of these disorders, with HLA-B27 as the strongest MHC-1 locus associated with SpA. To further investigate disease-causing genetic mutations, most of which occur in exons, Dr. Sharma is utilizing exome sequencing and functional analysis to identify possible disease-causing mechanisms in patients. 

            Education
              
            **All India Institute of Medical Sciences**Ph.D., Human Genetics (2015)             
                        Experience
              
            **Postdoctoral Fellow**National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH (2020-Present)**Postdoctoral Fellow**National Human Genome Research Institute, NIH (2018-2020)**Research Associate**Sanjay Gandhi Postgraduate Institute of Medical Sciences, India (2016-2018)


Last Updated: April 2024


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