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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Who Can Participate
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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High Blood PressureHigh Blood TriglyceridesHow Sleep WorksHow the Heart WorksHow the Lungs WorkIdiopathic Pulmonary FibrosisInsomniaInterstitial Lung DiseasesLAMLong QT SyndromeLow Blood PressureLung Disease TreatmentsMarfan SyndromeMetabolic SyndromeNarcolepsyNewborn Breathing ConditionsOverweight and ObesityPacemakersPeripheral Artery DiseasePhysical Activity and Your HeartPlatelet DisordersPleural DisordersPneumoniaPolycythemia VeraPrimary Ciliary DyskinesiaPulmonary RehabilitationRespiratory FailureSarcoidosisSickle Cell DiseaseSleep ApneaSleep Deprivation and DeficiencySleep StudiesSmoking and Your HeartStrokeTests for Lung DiseaseThalassemiaThe LungsTranscatheter Aortic Valve Replacement (TAVR)Treatments for Blood DisordersVasculitisVenous ThromboembolismVentilator/Ventilator SupportWhat Is Physical Activity?Women and Heart Disease

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Clear AllHigh Blood Pressure
Showing 1 - 10 out of 21 results
      
      Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health
      Recruiting
                          New York
        Are you a healthy adult who wants to join a study about less sitting? You might qualify for this research. Researchers are testing if walking breaks can improve cardiovascular health, like blood pressure and glucose (sugar) levels. To join, you must be 18 years old and have no long-term health issues or not be taking medications for blood pressure or diabetes. Participants will have to go to the study site for a 9-hour visit and walk on a treadmill during the day. The study is taking place in New York City, New York.
      Physical Activity and Your Heart
              Heart-Healthy Living
              Pulmonary Hypertension
              High Blood Pressure
              Low Blood Pressure
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
      Recruiting
                          North Carolina
        The purpose of this research is to learn about how salt in the diet influences blood pressure in young adults who were born prematurely.
      Pulmonary Hypertension
              Low Blood Pressure
              High Blood Pressure
                          Adult
                                      Accepting Healthy Volunteers
    Team-Based Home Blood Pressure Monitoring
      Recruiting
                          New York
        Do you have high blood pressure? In this clinical trial, researchers are studying different ways to improve home blood pressure monitoring. You may be able to participate if you are between 18 and 85 years old and diagnosed with high blood pressure. Participants will work closely with clinicians or other healthcare providers to schedule appointments, coordinate care, measure blood pressure, answer your questions, and treat your high blood pressure. The study is taking place in Rochester, New York.
      High Blood Pressure
              Low Blood Pressure
              Pulmonary Hypertension
                          Adult, Older Adult
    Mobile Health Program for Rural Hypertension
      Recruiting
                          Pennsylvania
        Do you have high blood pressure? If so, you may be able to participate in a clinical research study. Researchers are testing a home-based blood pressure monitoring program that provides health education, guidance, monitoring, and patient coaching to people who live in rural areas. You must be at least 18 years old to participate and be taking medication for high blood pressure. The study is taking place in Pittsburgh, Pennsylvania.
      High Blood Pressure
                          Adult, Older Adult
    LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure
      Recruiting
                          Michigan
        Have you been taking medication to treat high blood pressure for at least 3 months? In this study, researchers explore whether a smartphone app can help people eat less salt and improve their blood pressure. Participants must be at least 18 years old, be taking medication to treat high blood pressure, and have a smartphone. The study is taking place in Ann Arbor, Michigan.
      High Blood Pressure
                          Adult, Older Adult
    The Clinical Referral to Activity Study
      Recruiting
                          Pennsylvania
        Do you have high blood pressure, high A1C levels, or have overweight or obesity? Researchers are testing if a program helps increase physical activity for people at risk of cardiovascular disease. Participants will receive remote coaching and wear a physical activity tracker. To join, you must be 40 to 70 years old and can access the internet. The study is taking place in Pittsburgh, Pennsylvania.
      High Blood Pressure
              Overweight and Obesity
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    The Pregnancy 24/7 Cohort Study
      Recruiting
                          Iowa
              Pennsylvania
              West Virginia
        The overall goal of this study is to use state-of-the-art monitors to objectively measure the 24-hour behavioral cycle in each trimester of pregnancy, and to examine associations of these behaviors with hypertensive disorders of pregnancy and other adverse pregnancy outcomes linked with future cardiovascular disease risk.
      High Blood Pressure
                          Adult
                                      Accepting Healthy Volunteers
                                              Female
    The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.
      Recruiting
                          Alabama
        The Achieve Trial is a randomized clinical trial to test whether lowering blood pressure to less than 140/90 mmHg in women with hypertensive disorders of pregnancy will prolong pregnancy.
      High Blood Pressure
                          Child, Adult
                                            Female
    Angiotensin-(1-7) Cardiovascular Effects in Aging
      Recruiting
                          Pennsylvania
        Are you interested in participating in a clinical trial on heart health? In this trial, researchers are testing ways to help lower blood pressure and reduce cardiovascular disease as people age. To participate, you must be 65 to 80 years old, and you must not have high blood pressure or take medication for high blood pressure. The study is taking place in Hershey, Pennsylvania.
      High Blood Pressure
              Coronary Heart Disease
                          Older Adult
                                      Accepting Healthy Volunteers
    Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients
      Recruiting
                          Florida
        Are you an adult whose high blood pressure does not improve with lifestyle changes and medicines?
                    This study will assess whether minocycline, an antibiotic with anti-inflammatory effects, can improve blood pressure control in patients who do not respond to medicines in combination with lifestyle changes, such as physical activity, weight loss, and healthy eating patterns. To participate you must be at least 18 years old and have high blood pressure that does not respond to treatment with three different high blood pressure medicines even when used at the maximum doses. Please note that this study is in Gainesville, Florida.
      High Blood Pressure
                          Adult, Older Adult
  
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