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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Who Can Participate
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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          CLEARAcute Respiratory Distress SyndromeAlpha-1 Antitrypsin DeficiencyAnemiaAngina (Chest Pain)Aortic AneurysmAplastic AnemiaArrhythmiasAsthmaAtherosclerosisAtrial FibrillationBleeding DisordersBlood CholesterolBlood Clotting DisordersBronchiectasisBronchitisCardiac ArrestCardiac CatheterizationCardiogenic ShockCardiomyopathyChildhood ObesityCircadian Rhythm DisordersConduction DisordersCongenital Heart DefectsCOPDCoronary Artery Bypass Grafting(-)
Coronary Heart DiseaseCystic FibrosisDeep Vein Thrombosis (DVT)DefibrillatorsGet Regular Physical ActivityHeart-Healthy LivingHeart AttackHeart FailureHeart InflammationHeart SurgeryHeart TestsHeart TransplantHeart TreatmentsHeart Valve DiseasesHemolytic AnemiaHigh Blood PressureHigh Blood TriglyceridesHow Sleep WorksHow the Heart WorksHow the Lungs WorkIdiopathic Pulmonary FibrosisInsomniaInterstitial Lung DiseasesLAMLong QT SyndromeLow Blood PressureLung Disease TreatmentsMarfan SyndromeMetabolic SyndromeNarcolepsyNewborn Breathing ConditionsOverweight and ObesityPacemakersPeripheral Artery DiseasePhysical Activity and Your HeartPlatelet DisordersPleural DisordersPneumoniaPolycythemia VeraPrimary Ciliary DyskinesiaPulmonary HypertensionPulmonary RehabilitationRespiratory FailureSarcoidosisSickle Cell DiseaseSleep ApneaSleep Deprivation and DeficiencySleep StudiesSmoking and Your HeartStrokeTests for Lung DiseaseThalassemiaThe LungsTranscatheter Aortic Valve Replacement (TAVR)Treatments for Blood DisordersVasculitisVenous ThromboembolismVentilator/Ventilator SupportWhat Is Physical Activity?Women and Heart Disease

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Clear AllCoronary Heart Disease
Showing 1 - 10 out of 27 results
      
      Mental Stress Reactivity in Women With CMD
      Recruiting
                          Georgia
        Are you a woman with coronary microvascular dysfunction? In this clinical trial, researchers are studying coronary microvascular dysfunction, which occurs when there are problems in the small blood vessels in the heart. It frequently causes chest pain and is more common in women. The researchers want to learn how daily life and mental stress affect the heart. You may be able to participate if you are at least 45 years old, have gone through menopause, and are willing to undergo tests to measure your stress level. The study is taking place at locations in Atlanta, Georgia.
      Coronary Heart Disease
              Women and Heart Disease
                          Adult, Older Adult
                                            Female
    Sitting Interruption and Whole-body Cardiovascular Health
      Recruiting
                          North Carolina
        Are you an adult who gets little exercise and sits a lot every day? If you sit for more than 8 hours a day and exercise less than 90 minutes per week, this study may interest you. Researchers want to see if walking or standing breaks during long sitting periods can make your heart healthier. To take part in this study, you must be 36 to 55 years old. You also should be able to walk four blocks and go up two flights of stairs. The study is taking place in Chapel Hill, North Carolina.
      Physical Activity and Your Heart
              Heart-Healthy Living
              Stroke
              Coronary Heart Disease
                          Adult
                                      Accepting Healthy Volunteers
    Mediators of Atherosclerosis in South Asians Living in America
      Recruiting
                          California
              Illinois
              New York
        Is your family from India, Pakistan, Bangladesh, Nepal, or Sri Lanka? If so, you may be able to participate in a clinical study looking at cardiovascular disease, such as heart disease and stroke among people of South Asian descent. Participants must be between 40 and 84 years old and have no history of heart attack or stroke, heart failure, angina, or atrial fibrillation. This study is taking place in San Francisco, California, Chicago, Illinois, and New York City, New York.
      Atherosclerosis
              Coronary Heart Disease
                          Adult, Older Adult
    NHLBI-Emory Advanced Cardiac CT Reconstruction
      Not yet recruiting
                          Georgia
              Maryland
        Do you have heart disease?
                    This study is looking to improve the quality of heart CT scans by using new methods to create the images. You may be able to participate in the study if you are 18 years old or older, have heart disease, and have been told by your doctor that you need a CT scan. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.
      Heart Tests
              Coronary Heart Disease
                          Adult, Older Adult
    Risk Underlying Rural Areas Longitudinal Cohort Study (RURAL) Heart and Lung Study
      Recruiting
                          Alabama
        Have you lived in Alabama, Kentucky, Louisiana, or Mississippi for at least two years and are you interested in participating in a clinical study where researchers are trying to better understand health and disease in rural areas? The study team will track your physical activity using a provided Fitbit device and will also ask questions about your health and lifestyle through a cell phone app. You will also receive a kit to measure environmental and health factors in your homes. Participants must live in one of these counties: Dallas County, Alabama; Wilcox County, Alabama; Boyle County, Kentucky; Perry County, Kentucky; Garrard County, Kentucky; Breathitt County, Kentucky; Assumption Parish, Louisiana; Franklin Parish, Louisiana; Oktibbeha County, Mississippi; and Panola County, Mississippi.
      Pulmonary Hypertension
              Coronary Heart Disease
                          Adult
                                      Accepting Healthy Volunteers
    Hot Flashes and Neurovascular Function in Women
      Recruiting
                          Minnesota
        Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. In this clinical trial, researchers are studying the link between hot flashes and cardiovascular disease in women. Participants must be between 40 and 60 years old and must not have cardiovascular disease. The study is taking place in Rochester, Minnesota.
      Coronary Heart Disease
                          Adult
                                      Accepting Healthy Volunteers
                                              Female
    Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
      Recruiting
                          Multiple Locations
        Are you 75 years old or older and interested in participating in a clinical trial where researchers are studying whether statins, which are often used to treat high cholesterol, can help improve heart and brain health. To participate, you cannot have cardiovascular disease or dementia. The study is taking place at locations in Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Virginia, West Virginia, Wisconsin, and Puerto Rico.
      Coronary Heart Disease
                          Older Adult
                                      Accepting Healthy Volunteers
    A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
      Recruiting
                          Minnesota
        Have you had a heart attack caused by spontaneous coronary artery dissection (SCAD)? Most patients with SCAD do not have traditional risk factors such as tobacco use, high cholesterol, diabetes, but rather, they the heart attack is caused by other problems with the heart. In this clinical trial, researchers are studying people who have had SCAD to understand what may cause this to happen. The study is taking place in Rochester, Minnesota.
      Coronary Heart Disease
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
                                              Female
    An Ascending Dose Comparison of MVT-100 to Definity in Healthy Volunteers
      Recruiting
                          Missouri
              Nebraska
        Are you interested in participating in clinical research about ultrasounds? Ultrasounds are one of the most common ways to take images of the inside of your body. In some cases, something called a contrast agent is injected through an IV to make your organs even more visible during the ultrasound. Researchers in this clinical trial are comparing a new type of contrast agent to the current type used in ultrasounds. Participants must be 19 years old and considered to be generally healthy. The study is taking place in Kansas City, Missouri, and Omaha, Nebraska.
      Coronary Heart Disease
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health
      Recruiting
                          Massachusetts
        Have you been diagnosed with carotid artery stenosis? If you are over the age of 18 and have had an image scan for a diagnosis of carotid artery stenosis, you may be able to participate in this study. Researchers are trying to learn more about the ability of positron emission tomography (PET) scans to identify people with carotid artery stenosis who have no symptoms but who may be at risk of having a stroke. The study is taking place in Boston, Massachusetts.
      Coronary Heart Disease
                          Adult, Older Adult
  
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