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          About NIAMS
          Katherine Pak, M.D.





Katherine Pak, M.D.


Research Fellow
    Muscle Disease Section Portrait of Katherine Pak. 
            Contact Information

                                                  301-451-9977
                
                                                9000 Rockville Pike
                  
            50 South Drive
      
                  
            Building 50, Room 1142
      
                                   Bethesda MD 20892
                
                                                katherine.pak@nih.gov 
                                          Media Resources
                                  
            High Resolution Image 
                Summary
          Katherine S. Pak, M.D., joined the Muscle Disease Unit of the NIH/NIAMS in 2014 as a Research Fellow. Dr. Pak graduated from Korea University College of Medicine, South Korea in 1999 and went on to complete her Obstetrics and Gynecology (OB/GYN) residency training at the Samsung Cheil Hospital & Women’s Healthcare Center in Seoul. Between 2003 and 2006, Dr. Pak worked as an OB/GYN specialist at the Ilsan Jeil Hospital. In 2009, she relocated to the United States from South Korea and joined the Rheumatology Department of the Johns Hopkins University School of Medicine Research Program.
        
                  Research Statement
          
            Dr. Pak's research interests include immunology and rheumatology, specifically understanding the pathophysiology of autoimmune myositis. Her current focus is on analyzing RNA Seq data with next generation sequencing techniques, data science, and bioinformatics. 

            Scientific Publications
              The indirect immunofluorescence assay autoantibody profiles of myositis patients without known myositis-specific autoantibodies.

    Casal-Dominguez M, Pinal-Fernandez I, Pak K, Marin-Sanchez A, Sanz-Martinez MT, Baucells A, Hosono Y, Christopher-Stine L, Mammen AL, Johns Hopkins Myositis Center Group
        

                    Clin Exp Rheumatol.
        
                    2021 May-Jun;
        
                    39(3).
        
                    doi: 10.55563/clinexprheumatol/7kyr5e
                            PMID: 32896249
  Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis.

    Pinal-Fernandez I, Casal-Dominguez M, Derfoul A, Pak K, Miller FW, Milisenda JC, Grau-Junyent JM, Selva-O'Callaghan A, Carrion-Ribas C, Paik JJ, Albayda J, Christopher-Stine L, Lloyd TE, Corse AM, Mammen AL
        

                    Ann Rheum Dis.
        
                    2020 Sep;
        
                    79(9).
        
                    doi: 10.1136/annrheumdis-2019-216599
                            PMID: 32546599
  Neutrophil dysregulation is pathogenic in idiopathic inflammatory myopathies.

    Seto N, Torres-Ruiz JJ, Carmona-Rivera C, Pinal-Fernandez I, Pak K, Purmalek MM, Hosono Y, Fernandes-Cerqueira C, Gowda P, Arnett N, Gorbach A, Benveniste O, Gómez-Martín D, Selva-O'Callaghan A, Milisenda JC, Grau-Junyent JM, Christopher-Stine L, Miller FW, Lundberg IE, Kahlenberg JM, Schiffenbauer AI, Mammen A, Rider LG, Kaplan MJ
        

                    JCI Insight.
        
                    2020 Feb 13;
        
                    5(3).
        
                    pii: 134189. doi: 10.1172/jci.insight.134189
                            PMID: 31945019
  Validation of anti-Mi2 autoantibody testing by line blot.

    Pinal-Fernandez I, Pak K, Casal-Dominguez M, Hosono Y, Mecoli C, Christopher-Stine L, Mammen AL
        

                    Autoimmun Rev.
        
                    2020 Jan;
        
                    19(1).
        
                    doi: 10.1016/j.autrev.2019.102425
                            PMID: 31734399
  Trim33 (Tif1γ) is not required for skeletal muscle development or regeneration but suppresses cholecystokinin expression.

    Parks CA, Pak K, Pinal-Fernandez I, Huang W, Derfoul A, Mammen AL
        

                    Sci Rep.
        
                    2019 Dec 6;
        
                    9(1).
        
                    doi: 10.1038/s41598-019-54651-8
                            PMID: 31811178
  Anti-NT5C1A autoantibodies are associated with more severe disease in patients with juvenile myositis.

    Yeker RM, Pinal-Fernandez I, Kishi T, Pak K, Targoff IN, Miller FW, Rider LG, Mammen AL, Childhood Myositis Heterogeneity Collaborative Study Group
        

                    Ann Rheum Dis.
        
                    2018 May;
        
                    77(5).
        
                    doi: 10.1136/annrheumdis-2017-212436
                            PMID: 29363513
  Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients.

    Kishi T, Rider LG, Pak K, Barillas-Arias L, Henrickson M, McCarthy PL, Shaham B, Weiss PF, Horkayne-Szakaly I, Targoff IN, Miller FW, Mammen AL, Childhood Myositis Heterogeneity Study Group
        

                    Arthritis Care Res (Hoboken).
        
                    2017 Jul;
        
                    69(7).
        
                    doi: 10.1002/acr.23113
                            PMID: 28129483
  Anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase necrotizing myopathy masquerading as a muscular dystrophy in a child.

    Mohassel P, Foley AR, Donkervoort S, Fequiere PR, Pak K, Bönnemann CG, Mammen AL
        

                    Muscle Nerve.
        
                    2017 Dec;
        
                    56(6).
        
                    doi: 10.1002/mus.25567
                            PMID: 28066895 
          Education
              
            **Samsung Cheil Hospital & Women’s Healthcare Center, Seoul, South Korea**
Obstetrics and Gynecology (OB/Gyn) Residency (1999-2003)

**Korea University College of Medicine, Seoul, South Korea**
Radiation Oncology Residency (1997-1999)

**Korea University College of Medicine, Seoul, South Korea**
Transitional Year as Internship (1996-1997)

**Korea University College of Medicine, Seoul, South Korea**
Medical Degree (1995)             
                        Experience
              
            **Research Fellow**
Muscle Disease Unit, NIH/NIAMS (August 2014-present)

**Research Specialist**
Johns Hopkins School of Medicine, Rheumatology Department (September 2009-May 2014)

**OB/GYN Specialist**
Ilsan Jeil Hospital, Ilsan, South Korea (2003-2006)

**OB/GYN Resident**
Samsung Cheil Hospital & Women’s Healthcare Center, Seoul, South Korea (1999-2003)

**Radiation Oncology Resident**
Korea University College of Medicine, Seoul, South Korea (1997-1999)

**Transitional Year**
Korea University College of Medicine, Seoul, South Korea (1996-1997)


Last Updated: September 2022


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