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          About NIAMS
          Kan Jiang, Ph.D.





Kan Jiang, Ph.D.


Staff Scientist
    Biodata Mining and Discovery Section Portrait of Kan Jiang. 
            Contact Information

                                                  301-594-3155
                
                                                9000 Rockville Pike
                  
                  
            Building 50, Room 1140
      
                                   Bethesda MD 20892
                
                                                jiangk@mail.nih.gov 
                                          Media Resources
                                  
            High Resolution Image 
                Summary
          Dr. Jiang received her Ph.D. from Aachen University in Germany and obtained her post-doctoral training at NCI and NIAMS, where she focused on the roles of transcription factors, chromatin regulators and epigenetic markers of immune cells. In 2018 she joined the Biodata Mining and Discovery Section.
        
                  Research Statement
          
            Studies of Functions of genomics, epigenomics and transcriptomics through Next Generation Sequencing methods and approaches, focusing on CHIP-Seq, RNA-Seq, ATAC-Seq and HiC. 

            Scientific Publications
              Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.

    Mistry P, Nakabo S, O'Neil L, Goel RR, Jiang K, Carmona-Rivera C, Gupta S, Chan DW, Carlucci PM, Wang X, Naz F, Manna Z, Dey A, Mehta NN, Hasni S, Dell'Orso S, Gutierrez-Cruz G, Sun HW, Kaplan MJ
        

                    Proc Natl Acad Sci U S A.
        
                    2019 Dec 10;
        
                    116(50).
        
                    doi: 10.1073/pnas.1908576116
                            PMID: 31754025
  A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans.

    Tsai PF, Dell'Orso S, Rodriguez J, Vivanco KO, Ko KD, Jiang K, Juan AH, Sarshad AA, Vian L, Tran M, Wangsa D, Wang AH, Perovanovic J, Anastasakis D, Ralston E, Ried T, Sun HW, Hafner M, Larson DR, Sartorelli V
        

                    Mol Cell.
        
                    2018 Jul 5;
        
                    71(1).
        
                    doi: 10.1016/j.molcel.2018.06.008
                            PMID: 29979962
  EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

    Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A
        

                    Sci Rep.
        
                    2015 Jun 19;
        
                    5().
        
                    doi: 10.1038/srep10643
                            PMID: 26090605
  Regulation of the MAD1 promoter by G-CSF.

    Jiang K, Hein N, Eckert K, Lüscher-Firzlaff J, Lüscher B
        

                    Nucleic Acids Res.
        
                    2008 Mar;
        
                    36(5).
        
                    doi: 10.1093/nar/gkn002
                            PMID: 18203738 
          Education
              
            Aachen University (RWTH), Aachen, Germany, Ph.D.
	Huazhong University of Science and Technology, China, M.S.
	Tongji Medical University, China, B.S. & M.D.             
                        Experience
              
            Staff Scientist BMDS, OST, NIAMS, NIH
	Postdoctoral Fellow NCI & NIAMS, NIH
	Resident Wuhan Children’s Hospital, Hubei Province, China


Last Updated: October 2022


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