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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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          Disease or Condition
        
          CLEARAcute Respiratory Distress SyndromeAlpha-1 Antitrypsin DeficiencyAnemiaAngina (Chest Pain)Aortic AneurysmAplastic AnemiaArrhythmiasAsthmaAtherosclerosisAtrial FibrillationBleeding DisordersBlood CholesterolBlood Clotting DisordersBronchiectasisBronchitisCardiac ArrestCardiac CatheterizationCardiogenic ShockCardiomyopathyChildhood ObesityCircadian Rhythm DisordersConduction DisordersCongenital Heart DefectsCOPDCoronary Artery Bypass GraftingCoronary Heart DiseaseCystic FibrosisDeep Vein Thrombosis (DVT)DefibrillatorsGet Regular Physical ActivityHeart-Healthy LivingHeart AttackHeart FailureHeart InflammationHeart SurgeryHeart TestsHeart TransplantHeart TreatmentsHeart Valve DiseasesHemolytic AnemiaHigh Blood PressureHigh Blood TriglyceridesHow Sleep WorksHow the Heart WorksHow the Lungs WorkIdiopathic Pulmonary FibrosisInsomnia(-)
Interstitial Lung DiseasesLAMLong QT SyndromeLow Blood PressureMarfan SyndromeMetabolic SyndromeNarcolepsyNewborn Breathing ConditionsOverweight and ObesityPacemakersPeripheral Artery DiseasePhysical Activity and Your HeartPlatelet DisordersPleural DisordersPneumoniaPolycythemia VeraPrimary Ciliary DyskinesiaPulmonary HypertensionPulmonary RehabilitationSarcoidosisSickle Cell DiseaseSleep ApneaSleep Deprivation and DeficiencySleep StudiesSmoking and Your HeartTests for Lung DiseaseThalassemiaThe LungsTranscatheter Aortic Valve Replacement (TAVR)Treatments for Blood DisordersVasculitisVenous ThromboembolismWhat Is Physical Activity?Women and Heart Disease

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Clear AllInterstitial Lung Diseases
Showing 1 - 6 out of 6 results
      
      The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
      Recruiting
                          Multiple Locations
        DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 24-27 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure within (T) 5 days (120 hours) of extubation.
      Interstitial Lung Diseases
              Lung Disease Treatments
                          Child
    Electronic Nicotine Delivery Devices and Potential Progression to Acute Lung Injury
      Recruiting
                          Pennsylvania
        This is an observational - data and specimen collection study. There have been increasing reports of vaping-induced lung injury, including severe lung injury and rare cases of death. The mechanism by which vaping contributes to lung injury in susceptible persons is unknown, as is impact on chronic lung disease. The investigators aim to identify individuals with chronic electronic nicotine delivery device (ENDD) exposure and matched controls within our ongoing cohort of HIV+ and HIV-uninfected individuals, collect PFT data, bank respiratory and stool samples and collect clinical data for studies of clinical risk, inflammation, biomarkers, and the microbiome in the identification and modification of risk of progression to lung injury or chronic pulmonary disease.
      Interstitial Lung Diseases
              Tests for Lung Disease
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    Regadenoson Infusion of Marginalized Donor Lungs in an EVLP System
      Recruiting
                          Maryland
              Ohio
        The purpose of this study is to see if adding a drug called Regadenoson to the EVLP circulation reservoir during perfusion of marginal donor lungs will help increase the likelihood that the donor lungs will become usable for transplantation.
      Idiopathic Pulmonary Fibrosis
              Cystic Fibrosis
              Interstitial Lung Diseases
              Lung Disease Treatments
                          Adult, Older Adult
    Assessment of Continuous Positive Airway Pressure Therapy in IPF
      Recruiting
                          New York
        The purpose of this study is to evaluate whether biomarkers of lung injury and remodeling are responsive to effective continuous positive airway pressure (CPAP) treatment in adults with idiopathic pulmonary fibrosis (IPF) and moderate-to-severe obstructive sleep apnea (OSA).
      Interstitial Lung Diseases
              Sleep Apnea
                          Adult, Older Adult
    Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients
      Recruiting
                          Massachusetts
        Are you an adult who has idiopathic pulmonary fibrosis or an advanced lung cancer?
                    This study aims to see whether a new imaging dye for positron emission tomography (PET) is effective at looking at fibrosis in lung cancer and idiopathic pulmonary fibrosis (IPF). Participants will be given the imaging dye and then receive a PET scan. To participate in this study, you must either be between 18 and 80 years old and have lung cancer or be a healthy volunteer or be between 50 and 80 years old and have IPF. This study is located in Boston, Massachusetts.
      Idiopathic Pulmonary Fibrosis
              Interstitial Lung Diseases
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis (STRIVE-IPF)
      Recruiting
                          Multiple Locations
        Are you between 40 and 85 with worsening idiopathic pulmonary fibrosis?
                    This study aims to test a new combination treatment for acute exacerbations, a life-threatening complication of idiopathic pulmonary fibrosis (IPF) that has no approved treatment. The treatment is meant to help stop part of the immune system from further injuring the lung tissue. To participate in this study, you must be between 40 and 85 years old and have worsening IPF. This study is located in Birmingham, Alabama; Boston, Massachusetts; Philadelphia, Pennsylvania; and Pittsburgh, Pennsylvania.
      Idiopathic Pulmonary Fibrosis
              Interstitial Lung Diseases
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