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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Who Can Participate
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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CLEARAnemiaAplastic AnemiaArrhythmiasAtherosclerosisAtrial FibrillationBlood Clotting DisordersCardiomyopathyCircadian Rhythm DisordersCoronary Heart DiseaseHeart-Healthy LivingHeart FailureHemolytic AnemiaIdiopathic Pulmonary FibrosisInterstitial Lung DiseasesLAMOverweight and ObesityPeripheral Artery DiseaseSickle Cell DiseaseSleep Deprivation and DeficiencySmoking and Your HeartTreatments for Blood Disorders

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Clear AllIllinois
Showing 1 - 10 out of 35 results
      
      Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
      Recruiting
                          Illinois
        Demonstrating the feasibility, effectiveness, and cost-effectiveness of electronically delivered smoking cessation interventions via patient portals in Federally Qualified Health Care (FQHC) settings has the potential for wide-spread dissemination and significant public health impact. on patient populations with demonstrated high rates of smoking.
      Smoking and Your Heart
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden
      Recruiting
                          Multiple Locations
        The BashirTM Endovascular Catheter has been designed to administer therapeutic agents in the peripheral vasculature. Because of the unique design of the catheter, with its six expandable infusion limbs, the BashirTM Endovascular Catheter has the ability to: 1. Create a much larger central channel for blood flow, thereby utilizing the body's own endogenous fibrinolytic agents to lyse the clot, and 2. Greatly enhance the radial dispersion of a catheter-administered thrombolytic agent throughout the thrombus. Expansion of the multiple arms of the basket in the infusion catheter causes fissuring of the clot. The net result is that a greater surface area of clot is exposed to both endogenous and exogenously administered lytic agents, thereby promoting clot dissolution.
      Blood Clotting Disorders
                          Adult, Older Adult
    American Lung Association (ALA) Lung Health Cohort
      Recruiting
                          Multiple Locations
        The objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
      Adult
                                      Accepting Healthy Volunteers
    Mediators of Atherosclerosis in South Asians Living in America
      Recruiting
                          California
              Illinois
              New York
        Is your family from India, Pakistan, Bangladesh, Nepal, or Sri Lanka? If so, you may be able to participate in a clinical study looking at cardiovascular disease, such as heart disease and stroke among people of South Asian descent. Participants must be between 40 and 84 years old and have no history of heart attack or stroke, heart failure, angina, or atrial fibrillation. This study is taking place in San Francisco, California, Chicago, Illinois, and New York City, New York.
      Atherosclerosis
              Coronary Heart Disease
                          Adult, Older Adult
    A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)
      Recruiting
                          Multiple Locations
        The main goal of this study is to determine whether the treatment will lead to a complete absence of severe vaso-occlusive events (VOEs) in patients with severe SCD.
      Sickle Cell Disease
                          Child, Adult
    The Role of Body Fat Tissues in Endothelial Dysfunction
      Recruiting
                          Illinois
        Do you have both type II diabetes and obesity? Researchers are studying how exercise and weight-loss  affect body fat tissues and cells in the body. Participants must be 18 to 50 years old and be able to do moderately intense physical activity. The study is taking place in Chicago, Illinois.
      Overweight and Obesity
                          Adult
    Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
      Recruiting
                          Multiple Locations
        Are you 75 years old or older and interested in participating in a clinical trial where researchers are studying whether statins, which are often used to treat high cholesterol, can help improve heart and brain health. To participate, you cannot have cardiovascular disease or dementia. The study is taking place at locations in Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Virginia, West Virginia, Wisconsin, and Puerto Rico.
      Coronary Heart Disease
                          Older Adult
                                      Accepting Healthy Volunteers
    Safety and Durability of Sirolimus for Treatment of LAM
      Recruiting
                          Multiple Locations
        Are you an adult female with LAM? If so, you may be able to participate in this clinical study where researchers are observing patients who are taking or have taken a certain kind of medication, mammalian target of rapamycin (mTOR), to treat lymphangioleiomyomatosis, also known as LAM. You must be at least 18 years old to take part. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota, Missouri, New York, Ohio, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Utah, and Washington.
      LAM
                          Adult, Older Adult
                                            Female
    A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
      Recruiting
                          Multiple Locations
        This trial will compare time from randomization to failure of treatment or death from any cause of IST versus URD BMT when used as initial therapy to treat Severe Aplastic Anemia.
      Anemia
                          Child, Adult
    Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
      Recruiting
                          Illinois
        Do you have chronic kidney disease and mild heart failure? Researchers are testing a medication to see if it helps heart and lung function when it is added to your current medication. To take part in this clinical trial, you must be 18 to 85 years old, have chronic kidney disease and are taking diuretics or other medication, and have mild heart failure. The study is taking place in Chicago, Illinois.
      Heart Failure
                          Adult, Older Adult
  
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