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          About NIAMS
          Luz P. Blanco, Ph.D.





Luz P. Blanco, Ph.D.


Staff Scientist
    Systemic Autoimmunity Branch Portrait of Luz Blanco. 
            Contact Information

                                                  301-827-9526
                
                                                9000 Rockville Pike
                  
            10 Center Drive
      
                  
            Building 10, Room 253a
      
                                   Bethesda MD 20892
                
                                                luz.blanco@nih.gov 
                                          Media Resources
                                  
            High Resolution Image 
                Summary
          In 1987, Dr. Luz Blanco received her bachelor degree in biochemistry with a major in immunology at the Pontificia Universidad Catolica de Chile. In 1997, Dr. Blanco completed her Ph.D. in microbiology at University of Chile. In 1993 she secured a faculty position at Facultad de Ciencias Quimicas y Farmaceuticas Universidad de Chile being promoted to Assistant Professor of Immunology in 1997. From 2001 until 2013 she worked at University of Michigan after being awarded with a Latin American fellowship from the American Society of Microbiology with positions such as a sabbatical visiting scientist, postdoctoral fellow, senior postdoctoral fellow, and research investigator. In 2013, she was recruited as a staff scientist for the Systemic Autoimmunity branch at the NIAMS where she currently is doing research in the innate immune system role in autoimmunity and inflammation.
        
                  Research Statement
          
            Dr. Blanco is interested in how innate immune cells participate in autoimmune and inflammatory diseases, with a particular interest in neutrophils and the mechanisms involved in the regulation of their functionality. She is exploring possible therapeutic agents and mechanisms involved in the mitochondrial disfunction formerly reported in lupus disease by her and others. In addition, Dr. Blanco is studying how neutrophil extracellular traps affect the endothelial cell biology. 

            Scientific Publications
              Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction.

    Furumoto Y, Smith CK, Blanco L, Zhao W, Brooks SR, Thacker SG, Abdalrahman Z, Sciumè G, Tsai WL, Trier AM, Nunez L, Mast L, Hoffmann V, Remaley AT, O'Shea JJ, Kaplan MJ, Gadina M
        

                    Arthritis Rheumatol.
        
                    2017 Jan;
        
                    69(1).
        
                    doi: 10.1002/art.39818
                            PMID: 27429362
  Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.

    Lood C, Blanco LP, Purmalek MM, Carmona-Rivera C, De Ravin SS, Smith CK, Malech HL, Ledbetter JA, Elkon KB, Kaplan MJ
        

                    Nat Med.
        
                    2016 Feb;
        
                    22(2).
        
                    doi: 10.1038/nm.4027
                            PMID: 26779811
  Interferon-α and angiogenic dysregulation in pregnant lupus patients who develop preeclampsia.

    Andrade D, Kim M, Blanco LP, Karumanchi SA, Koo GC, Redecha P, Kirou K, Alvarez AM, Mulla MJ, Crow MK, Abrahams VM, Kaplan MJ, Salmon JE
        

                    Arthritis Rheumatol.
        
                    2015 Apr;
        
                    67(4).
        
                    doi: 10.1002/art.39029
                            PMID: 25603823
  Gender-biased regulation of human IL-17-producing cells in vitro by peptides corresponding to distinct HLA-DRB1 allele-coded sequences.

    Blanco LP, Plegue M, Fung-Leung WP, Holoshitz J
        

                    J Immune Based Ther Vaccines Antimicrob.
        
                    2013 Jul;
        
                    2(3).
        
                    doi: 10.4236/jibtva.2013.23004
                            PMID: 28748127
  Diversity, biogenesis and function of microbial amyloids.

    Blanco LP, Evans ML, Smith DR, Badtke MP, Chapman MR
        

                    Trends Microbiol.
        
                    2012 Feb;
        
                    20(2).
        
                    doi: 10.1016/j.tim.2011.11.005
                            PMID: 22197327

                
  Role of Oxidative Stress in Chronic Diseases


Last Updated: September 2021


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