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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Who Can Participate
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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CLEARAnemiaAngina (Chest Pain)Aplastic AnemiaArrhythmiasAtrial FibrillationBlood Clotting DisordersCardiomyopathyCongenital Heart DefectsCoronary Artery Bypass GraftingCoronary Heart DiseaseHeart FailureHeart SurgeryHeart Valve DiseasesHemolytic AnemiaHigh Blood PressureHow Sleep WorksInsomniaLAMLung Disease TreatmentsOverweight and ObesityPeripheral Artery DiseaseSickle Cell DiseaseSleep ApneaSleep Deprivation and DeficiencySleep StudiesStrokeTreatments for Blood Disorders

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Clear AllMichigan
Showing 1 - 10 out of 29 results
      
      Role of Sleep Reactivity in Shift Work Disorder
      Recruiting
                          Michigan
        The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.
      How Sleep Works
              Sleep Deprivation and Deficiency
              Sleep Studies
                          Adult, Older Adult
    Respiratory Virus Testing and Home Spirometry for the Screening of Bronchiolitis Obliterans Syndrome After Donor Stem Cell Transplant
      Recruiting
                          Multiple Locations
        This observational trial studies whether respiratory viruses are the cause of lung disease (bronchiolitis obliterans syndrome [BOS] or graft-versus-host disease of the lung) and changes in lung function in patients who have received a donor stem cell transplant. Patients with chronic graft-versus-host disease (cGVHD) are at higher risk of developing BOS. Studies have also shown that patients who had a respiratory viral illness early after their transplant are at higher risk of developing lung problems later on. Patients who are at risk and who already have BOS might benefit from being monitored more closely. Spirometry is a way of assessing a patient's lung function and is often used to diagnose lung disease. Spirometry measured at home with a simple handheld device may reduce the burden of performing pulmonary function testing at a facility and potentially help patients get their lung disease diagnosed and treated sooner.
      Lung Disease Treatments
                          All Ages
    tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden
      Recruiting
                          Multiple Locations
        The BashirTM Endovascular Catheter has been designed to administer therapeutic agents in the peripheral vasculature. Because of the unique design of the catheter, with its six expandable infusion limbs, the BashirTM Endovascular Catheter has the ability to: 1. Create a much larger central channel for blood flow, thereby utilizing the body's own endogenous fibrinolytic agents to lyse the clot, and 2. Greatly enhance the radial dispersion of a catheter-administered thrombolytic agent throughout the thrombus. Expansion of the multiple arms of the basket in the infusion catheter causes fissuring of the clot. The net result is that a greater surface area of clot is exposed to both endogenous and exogenously administered lytic agents, thereby promoting clot dissolution.
      Blood Clotting Disorders
                          Adult, Older Adult
    American Lung Association (ALA) Lung Health Cohort
      Recruiting
                          Multiple Locations
        The objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
      Adult
                                      Accepting Healthy Volunteers
    Role of Sleep Reactivity in Shift Work Disorder
      Recruiting
                          Michigan
        The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD).
      Sleep Deprivation and Deficiency
              Insomnia
                          Adult, Older Adult
    Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
      Recruiting
                          Michigan
        This research study is designed to learn, first, whether two anesthetics have different effects on collapse seen within the upper airway during sleep endoscopy.
      Sleep Apnea
                          Child
    Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
      Recruiting
                          Michigan
        The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).
      Sleep Apnea
                          Child, Adult
    LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure
      Recruiting
                          Michigan
        Have you been taking medication to treat high blood pressure for at least 3 months? In this study, researchers explore whether a smartphone app can help people eat less salt and improve their blood pressure. Participants must be at least 18 years old, be taking medication to treat high blood pressure, and have a smartphone. The study is taking place in Ann Arbor, Michigan.
      High Blood Pressure
                          Adult, Older Adult
    Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)
      Recruiting
                          Multiple Locations
        Does your child have Down Syndrome? Did they have a complete atrioventricular septal defect (CAVSD) repair within the first year of their life? Researchers in this study are investigating how the
brain develops in children with Down Syndrome who have congenital heart disease. To participate, your child must be between 5 and 12 years old and have Down Syndrome. The study will enroll children who have congenital heart disease as well as children who do not have congenital heart disease. The study is taking place in locations in Delaware, Georgia, Indiana, Massachusetts, Michigan, Missouri, New York, Ohio, Pennsylvania, South Carolina, Texas, Utah, Washington, D.C., and Toronto, Canada
      Congenital Heart Defects
                          Child
                                      Accepting Healthy Volunteers
    Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
      Recruiting
                          Multiple Locations
        Are you 75 years old or older and interested in participating in a clinical trial where researchers are studying whether statins, which are often used to treat high cholesterol, can help improve heart and brain health. To participate, you cannot have cardiovascular disease or dementia. The study is taking place at locations in Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Virginia, West Virginia, Wisconsin, and Puerto Rico.
      Coronary Heart Disease
                          Older Adult
                                      Accepting Healthy Volunteers
  
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