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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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CLEARAnemiaAplastic AnemiaArrhythmiasAtrial FibrillationCoronary Artery Bypass GraftingHeart FailureHeart SurgeryHemolytic AnemiaInterstitial Lung DiseasesLung Disease TreatmentsSickle Cell DiseaseStroke

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Clear AllNew Jersey
Showing 1 - 10 out of 10 results
      
      The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
      Recruiting
                          Multiple Locations
        DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 24-27 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure within (T) 5 days (120 hours) of extubation.
      Interstitial Lung Diseases
              Lung Disease Treatments
                          Child
    A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
      Recruiting
                          Multiple Locations
        This trial will compare time from randomization to failure of treatment or death from any cause of IST versus URD BMT when used as initial therapy to treat Severe Aplastic Anemia.
      Anemia
                          Child, Adult
    Renal Denervation + PVI vs PVI Alone for Persistent AF
      Recruiting
                          New Jersey
        This study is looking to determine if patients with persistent AF with controlled hypertension or without hypertension who are referred for catheter ablation (PVI) and undergo adjunctive RDN have reduced AF burden at 12 months in comparison to patients who undergo only PVI
      Atrial Fibrillation
                          Adult, Older Adult
    The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
      Recruiting
                          Multiple Locations
        Are you an adult with atrial fibrillation? In this study, researchers are comparing a continuous direct oral anticoagulation (DOAC) use versus time-limited (1 month) DOAC guided by an AF-sensing Smart Watch (AFSW) for persons with atrial fibrillation and a moderate risk of stroke. Participants must be between the ages of 22 and 85 and have a history of atrial fibrillation. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, South Carolina, Texas, Virginia, Wisconsin, and Washington, D.C.
      Atrial Fibrillation
                          Adult, Older Adult
    Bone Marrow Transplantation vs. Standard of Care in Patients With Severe Sickle Cell Disease
      Recruiting
                          Multiple Locations
        Are you 15 to 40 years old and have severe sickle cell disease?
                    This study is comparing long-term outcomes for patients who receive blood and bone marrow transplants and those who receive standard treatment with medicines. Participants also have an option of contributing blood samples to be stored for future research. Participants must be 15 to 40 years old and have severe sickle cell disease. This study is located in Madison, Wisconsin.
      Sickle Cell Disease
                          Child, Adult
    Transplants With Unlicensed Preserved Cord Blood
      Recruiting
                          Multiple Locations
        Are you scheduled for a stem cell transplant with cord blood?
                    This study will assess the safety and effectiveness of certain cord blood transplants. The study will help researchers learn the best methods for collecting, storing, and using cord blood in transplants. To participate in this study, you must have a disorder that compromises your body’s ability to make blood cells. This study is located in Bethesda, Maryland.
      Anemia
              Hemolytic Anemia
              Aplastic Anemia
                          All Ages
    Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)
      Recruiting
                          Multiple Locations
        Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery?
                    Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
      Arrhythmias
              Atrial Fibrillation
              Coronary Artery Bypass Grafting
              Stroke
              Heart Surgery
                          Adult, Older Adult
    Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction (SPIRRIT)
      Recruiting
                          Multiple Locations
        Do you want to help find new treatments for heart failure with preserved ejection fraction? 
                    This study is testing whether a medicine called spironolactone can help treat heart failure with preserved ejection fraction when paired with the standard treatment. Spironolactone helps to remove excess water and sodium from the body. To participate in this study, you must be between 50 and 99 years old and diagnosed with heart failure with preserved ejection fraction.
      Heart Failure
                          Adult, Older Adult
    Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction (SPIRRIT)
      Recruiting
                          Multiple Locations
        Do you have heart failure with preserved ejection fraction (HFPEF)? This study is testing the efficacy of a diuretic medicine called spironolactone that stops your body from absorbing too much salt and keeps your potassium levels from dropping too low. Participants of this study must be between 50 and 99 years old and already taking diuretic medicine. This study takes place in multiple locations across the United States and Sweden.
      Heart Failure
                          Adult, Older Adult
    His-Bundle Corrective Pacing in Heart Failure (HIS-CRT)
      Recruiting
                          Illinois
              New Jersey
              Vermont
        Are you an adult with heart failure and right bundle branch block (RBBB)? This study will evaluate the effectiveness and benefit of His-bundle-pacing enhanced cardiac resynchronization therapy (His-CRT) versus cardiac resynchronization therapy (BiV-CRT). This study is located in Rochester, New York.
      Arrhythmias
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