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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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      Who Can Participate
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      Benefits, Risks & Safety Measures
Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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CLEARAnemiaAplastic AnemiaArrhythmiasAsthmaAtrial FibrillationBronchiectasisCardiomyopathyCoronary Artery Bypass GraftingCoronary Heart DiseaseCystic FibrosisHeart SurgeryHemolytic AnemiaHow the Lungs WorkLAMOverweight and ObesityPneumoniaPrimary Ciliary DyskinesiaPulmonary HypertensionRespiratory FailureStrokeThe LungsTranscatheter Aortic Valve Replacement (TAVR)Treatments for Blood Disorders

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Clear AllColorado
Showing 1 - 10 out of 28 results
      
      Pulmonary Health in Children With Down Syndrome
      Recruiting
                          Colorado
        The goal of the study is to learn more about tests that can assess lung health in children with Down syndrome.
      How the Lungs Work
                          Child, Adult
    American Lung Association (ALA) Lung Health Cohort
      Recruiting
                          Multiple Locations
        The objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
      Adult
                                      Accepting Healthy Volunteers
    Optimizing Pulsatility During Cardiopulmonary Bypass
      Recruiting
                          Colorado
        Are you scheduled for cardiac bypass surgery? Cardiac surgery is effective for improving the health of patients with cardiovascular disease, but many patients experience complications. In this clinical trial, researchers are collecting data to learn how different types of bypasses affect patients. You must be 50 to 70 years old to participate and be scheduled for elective cardiac surgery. The study is taking place in Aurora, Colorado.
      Adult, Older Adult
    Pulmonary Health in Children With Down Syndrome
      Recruiting
                          Colorado
        The goal of the study is to learn more about tests that can assess lung health in children with Down syndrome.
      The Lungs
                          Child, Adult
    Safety and Durability of Sirolimus for Treatment of LAM
      Recruiting
                          Multiple Locations
        Are you an adult female with LAM? If so, you may be able to participate in this clinical study where researchers are observing patients who are taking or have taken a certain kind of medication, mammalian target of rapamycin (mTOR), to treat lymphangioleiomyomatosis, also known as LAM. You must be at least 18 years old to take part. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota, Missouri, New York, Ohio, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Utah, and Washington.
      LAM
                          Adult, Older Adult
                                            Female
    A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
      Recruiting
                          Multiple Locations
        This trial will compare time from randomization to failure of treatment or death from any cause of IST versus URD BMT when used as initial therapy to treat Severe Aplastic Anemia.
      Anemia
                          Child, Adult
    NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial
      Recruiting
                          Multiple Locations
        Are you at least 18 years old and have been told by your doctor that you need a procedure called transcatheter aortic valve replacement?
                    This study will test a new device designed specifically for use during a procedure called transcatheter aortic valve replacement. Researchers want to make transcatheter aortic valve replacement safer. To be in the study, you must be at least 18 and need a transcatheter aortic valve replacement. The study will take place in locations in California, Georgia, Massachusetts, New York, Virginia, Washington, and Washington, D.C.
      Transcatheter Aortic Valve Replacement (TAVR)
                          Adult, Older Adult
    Health Outcomes of Parents With Cystic Fibrosis
      Recruiting
                          Multiple Locations
        This project will determine the health impact of parenthood on people with cystic fibrosis (CF). The study team will use retrospective data to provide relatively immediate evidence on parenthood's effect on pulmonary health.
      Cystic Fibrosis
                          Adult, Older Adult
    The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
      Recruiting
                          Multiple Locations
        Are you an adult with atrial fibrillation? In this study, researchers are comparing a continuous direct oral anticoagulation (DOAC) use versus time-limited (1 month) DOAC guided by an AF-sensing Smart Watch (AFSW) for persons with atrial fibrillation and a moderate risk of stroke. Participants must be between the ages of 22 and 85 and have a history of atrial fibrillation. The study is taking place at locations in California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, South Carolina, Texas, Virginia, Wisconsin, and Washington, D.C.
      Atrial Fibrillation
                          Adult, Older Adult
    Structural Conditions and Health After Release From Prison
      Recruiting
                          Colorado
        Have you recently been released from state prison into the Denver/Aurora Colorado metro area? For this study, researchers are studying how people released from prison access healthcare services. The researchers will also see how many participants are hospitalized for heart issues. Study participants must be 18 years old, have recently been released from prison, and have no plans to leave the area within the next 6 months. The study is taking place in Aurora, Colorado.
      Coronary Heart Disease
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
  
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