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		Search Text: Clinical Trials
					
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            The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. Find studies for diseases and conditions and see if you or a loved one is eligible.
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      How Clinical Trials Work
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Find NHLBI Clinical Trials

Search selected NHLBI-supported clinical trials and observational studies by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
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Clear AllArrhythmias
Showing 1 - 10 out of 17 results
      
      Observational Study of Cardiac Arrhythmias in Subjects Treated With BTK Inhibitors
      Recruiting
                          Maryland
        Do you have cancer that is treated with something called Bruton's tyrosine kinase inhibitors or BKTi?
                    In this study, researchers want to learn more about Bruton's tyrosine kinase inhibitors, which are often used to treat cancer, affect the heart. You can participate in this study if you are currently receiving or will be receiving Bruton's tyrosine kinase inhibitors. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.
      Arrhythmias
                          Adult, Older Adult
    Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)
      Recruiting
                          Minnesota
        Are you a Minnesota resident with hypertrophic cardiomyopathy?
                    This study aims to find out how common it is for people with hypertrophic cardiomyopathy to also have sleep apnea. Hypertrophic cardiomyopathy is a disease that causes the heart muscle to thicken. Participants will also wear a heart rhythm monitor to help researchers learn whether sleep apnea is linked to arrhythmia. The study seeks healthy volunteers as well as participants in the Hypertrophic Cardiomyopathy Registry. To participate in this study, you must not have had a catheter ablation procedure to treat atrial fibrillation, had surgery to replace your heart valves, or been treated for sleep apnea. The study is located in Rochester, Minnesota.
      Arrhythmias
              Atrial Fibrillation
              Cardiomyopathy
              Sleep Apnea
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention (PROSe-ICD)
      Recruiting
                          Maryland
              Virginia
        Do you have heart disease that requires an ICD to prevent sudden cardiac arrest?
                    This study aims to learn what signs distinguish patients who have a higher risk of an arrhythmia that leads to sudden cardiac arrest. Researchers plan to track patients with a recent ICD replacement for 10 years. To participate in this study, you must be between 18 and 85 years old. This study is located in Washington, D.C.; Baltimore, Maryland; and Richmond, Virginia.
      Arrhythmias
              Defibrillators
                          Adult, Older Adult
    Identification of Genomic Predictors of Adverse Events After Cardiac Surgery (CABGGenomics)
      Recruiting
                          Massachusetts
              Texas
        Do you know someone who will be having heart surgery?
                    This study aims to identify what genetic patterns might cause atrial fibrillation and other adverse events that happen after heart surgery. To participate in this study, you must be between 20 and 90 years old. The study is in three locations in Massachusetts and Texas.
      Arrhythmias
              Atrial Fibrillation
                          Adult, Older Adult
    Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
      Recruiting
                          Wisconsin
        Does your developing baby have a heart defect? Have you had a stillborn baby?
                    This study tests a new technology to measure fetal heart activity and find possible problems early. These problems include fetal arrhythmia and conduction disorders such as Brugada syndrome. To participate in this study, you must be at least 18 years old and pregnant, and have one of five high-risk complications of pregnancy: a fetus with a major congenital heart defect, hydrops, or gastroschisis; a previous unexplained stillbirth; or twins who share a placenta. This study is located in Madison and Milwaukee, Wisconsin.
      Arrhythmias
              Congenital Heart Defects
              Conduction Disorders
                          Adult, Older Adult
                                            Female
    Pathophysiology of Orthostatic Intolerance
      Recruiting
                          Tennessee
        Have you been diagnosed with orthostatic intolerance?
                    This study aims to find out how the body’s regulation of basic functions, such as heart rate and blood pressure, is altered in people who have orthostatic intolerance. This condition, which has an unknown cause, is characterized by a racing heartbeat, dizziness, lightheadedness, and other symptoms that occur when a person stands up. To participate in this study, you must be between 18 and 80 years old and have orthostatic intolerance. This study is located in Nashville, Tennessee.
      Arrhythmias
              Low Blood Pressure
              Conduction Disorders
                          Adult, Older Adult
                                      Accepting Healthy Volunteers
    Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)
      Recruiting
                          Multiple Locations
        Did you develop atrial fibrillation after coronary artery bypass graft (CABG) surgery?
                    Did you develop atrial fibrillation after a coronary artery bypass grafting (CABG) surgery? This study is looking at how well oral anticoagulation medicines work to prevent complications, such as blood clots and heart attack, for patients who experience post-operative atrial fibrillation (POAF). This study is in multiple locations around the country.
      Arrhythmias
              Atrial Fibrillation
              Coronary Artery Bypass Grafting
              Stroke
              Heart Surgery
                          Adult, Older Adult
    Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
      Recruiting
                          Wisconsin
        Do you have a high-risk pregnancy? 
                    This study will investigate the use of a non-invasive scan called fetal magnetocardiography to detect potential problems in the fetus in five high-risk pregnancy conditions associated with stillbirth. The scan is normally used to look at fetal heart rhythms. To participate in this study, you must be at least 18 years old and pregnant with one of the following: having a stillbirth in a previous pregnancy, carrying identical twins, or having a fetus that has been diagnosed with major congenital heart disease, fetal hydrops, or fetal gastroschisis. This study takes place in Madison and Milwaukee, Wisconsin.
      Arrhythmias
              Congenital Heart Defects
              Long QT Syndrome
                          Adult, Older Adult
                                            Female
    Multiple Patient Program for Lamprene (clofazimine) for the treatment of Non-Tuberculous Mycobacterial (NTM) Infections- CLAM320B2002M
      Recruiting
                          
        Are you an adult with a non-tuberculous mycobacteria (NTM) infection? This study is testing the effectiveness of a medicine called clofazimine (Lamprene) to treat NTM. To participate in this study, you must be an adult with a NTM infection. This study is located at the NIH Clinical Center in Bethesda, Maryland.
      Bronchiectasis
              Arrhythmias
    "Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation (ICMREDUCE-AF) "
      Recruiting
                          New York
        Are you an adult with atrial fibrillation who recently had a catheter ablation procedure? This study will investigate the effectiveness of an implantable cardiac monitor-guided device to monitor participants for recurrent atrial fibrillation following ablation. This study is located in Rochester, New York.
      Atrial Fibrillation
              Arrhythmias
                          Adult, Older Adult
  
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