U.S. flag

An official website of the United States government

Here’s how you know
Here’s how you know

**Official websites use .gov**
A **.gov** website belongs to an official government organization in the United States.

**Secure .gov websites use HTTPS**
A **lock** ( A locked padlock) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Search Query:
			MAIN MENU

																				
              Health Topics
								All Health Topics A-Z
					
													
		

		Asthma


				

															Heart-Healthy Living


				

															High Blood Pressure


				

															Sickle Cell Disease


				

															Sleep Apnea


				

															Information & Resources on COVID-19
																				
              Health Education
								Education Programs and Initiatives
					
													
		

		The Heart Truth®


				

															Learn More Breathe Better®


				

															Blood Diseases and Disorders Education Program


				

															Publications and Resources
																				
              The Science
								Research Focus Areas
					
													
		

		Blood Disorders and Blood Safety


				

															Sleep Science and Sleep Disorders


				

															Lung Diseases


				

															Health Disparities and Inequities


				

															Heart and Vascular Diseases


				

															Precision Medicine Activities


				

															Obesity, Nutrition, and Physical Activity


				

															Population and Epidemiology Studies


				

															Women’s Health


				

															Research Topics


				

															Clinical Trials


				

															All Science A-Z
																				
              Grants and Training
								Grants and Training Home


				

															Policies and Guidelines


				

															Funding Opportunities and Contacts


				

															Training and Career Development
																				
              News and Events
								News and Events Home
					
													
		

		Email Alerts


				

															All News
					
													
		

		NHLBI News


				

															NHLBI in the Press


				

															Research Features


				

															All Events
					
													
		

		Past Events


				

															Upcoming Events
																				
              About NHLBI
								About NHLBI Home
					
													
		

		Mission and Strategic Vision


				

															Leadership


				

															Divisions, Offices and Centers


				

															Advisory Committees


				

															Budget and Legislative Information


				

															Jobs and Working at the NHLBI


				

															Contact and FAQs


				

															NIH Sleep Research Plan
						
						HOME
		Search Text: Home/About the NHLBI/< Back ToDivisions, Offices and Centers/Division of Blood Diseases and Resources

Division of Blood Diseases and Resources
                            

                                                        
            The Division of Blood Diseases and Resources (DBDR) is a leader in research on the causes, prevention, and treatment of non-neoplastic blood diseases. DBDR assumes a major responsibility in ensuring the adequacy and safety of the nation’s blood supply. It also supports scientific advances in stem cell biology and new gene and cell-based therapies developed to repair and regenerate human tissues and organs.
                                    Read more
            Blood diseases affect millions of people each year in the United States. These congenital and acquired diseases, including the anemias, venous thromboembolism, hemophilia, and other bleeding disorders, impact the normal biology of red and white blood cells, platelets, bone marrow, vascular endothelium, and plasma proteins. They also manifest a wide range of symptoms, generating the need for preventive, therapeutic, and curative approaches to restoring health.The DBDR is divided into three branches that are structured to facilitate team science in priority areas of blood science. Together, the branches foster the training of the next generation of blood scientists, coordinate blood research activities, and promote communication across the Division, the NHLBI, the NIH, and partner federal agencies.
      
                Read less
                                                On this page
                            What We Do
                                
                                                                    Related Scientific Focus Areas
                                                                                                    Related News and Events
                                                                                                                                    Contact Us
                            Stimulating and Supporting Blood Science Research to Improve Clinical Care
      
	-
		Division of Blood Diseases and Resources
    With a particular focus on understanding how blood diseases impact diverse populations, research within the DBDR has affected how physicians diagnose, assess, and treat across the spectrum of blood disorders. The research supporting these discoveries spans discovery, translational, and clinical science and includes these key aspects:Generating critical knowledge in disorders of blood, hemostasis, and vascular systems, and translating this knowledge into the discovery of diagnostic biomarkers and therapeutic targets. Research areas include systems biology, glycomics, thrombotic and hemostatic disorders, and vascular dysfunction in the pathogenesis of severe malaria.Establishing multicenter clinical research programs for rare and uncommon blood diseases to enhance participant recruitment, data collection, and analysis. Programs include the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) and the National Myelodysplastic Syndromes (MDS) StudyInforming the prevention and treatment of the complications of sickle cell anemia (SCA). Research includes the Stroke Prevention Trial in Sickle Cell Anemia (STOP), Optimizing Primary Stroke Prevention in Children With Sickle Cell Anemia (STOP II), Transcranial Doppler With Transfusions Changing to Hydroxyurea (TWiTCH), and the Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG).Developing and disseminating data science resources in patient-reported outcomes to facilitate phenotyping and cross-study analyses for clinical practice guidelines. Resources include the Pediatric Quality of Life Inventory (PedsQL) Sickle Cell Disease module, the Adult Sickle Cell Quality of Life Measurement Information System (ASCQ-Me), the Patient-Reported Outcomes Measurement Information System (PROMIS), the Validation of Pediatric Patient-Reported Outcomes in Chronic Diseases (PEPR), and Consensus Measures for Phenotypes and eXposures (PhenX).Ensuring the safety of the nation’s blood supply, improving blood transfusion benefits, and reducing associated risks. Research includes the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III), which the NHLBI recently expanded to ascertain the potential threat to the blood supply posed by the emergence of Zika virus.


          
    Facilitating the Translation of Discoveries Into Therapeutics
      
	-
		Division of Blood Diseases and Resources
    The NHLBI seeks to enable early translational research as a means of facilitating and accelerating the development of new clinical interventions. The NHLBI Catalyze Program provides a comprehensive suite of support and services to help translate basic scientific discoveries into viable therapeutics, devices, and diagnostics ready for human testing.


          
    Leading Precision Medicine Activities for Blood Diseases
      
	-
		Division of Blood Diseases and Resources
    The DBDR and other NHLBI divisions are involved with NHLBI’s Trans-Omics for Precision Medicine (TOPMed) Program, which will support the Institute’s larger precision medicine activities and complement the NIH All of Us Research Program. TOPMed will collect and couple whole-genome sequencing and other –omics data, such as DNA methylation signatures and RNA expression profiles, with molecular, behavioral, imaging, environmental, and clinical data from studies focused on heart, lung, blood, and sleep disorders. The TOPMed Program will provide more opportunities for the NHLBI community to pursue research that will further the understanding and improve the care of people with blood disorders.
                                    Division Leadership
                        photo of Julie Panepinto, M.D. MSPH
	            Julie Panepinto, M.D., MSPH
				Director
				
            julie.panepinto@nih.gov
                                    What We Do
                    
Blood Epidemiology and Clinical Therapeutics Branch
    The Blood Epidemiology and Clinical Therapeutics Branch provides oversight, support, and stimulation of epidemiologic, clinical, and implementation research throughout the spectrum of blood science. This spectrum includes benign blood diseases, as well as cell therapies such as hematopoietic stem cell transplants, transfusion products, and novel cell therapies. This branch also helps develop and disseminate data science resources in patient-reported outcomes. View funding information for the Blood Epidemiology and Clinical Therapeutics Branch.
        
            Contact:
    Traci Mondoro
                            Ph.D.
                            Acting Branch Chief
                            mondorot@nhlbi.nih.gov
                                                                                                
        Molecular Cellular and Systems Blood Science Branch
    The Molecular, Cellular, and Systems Blood Science Branch seeks to advance discovery science focused on explaining the physiology and pathophysiology of blood, bone marrow, and blood vessels. This Branch promotes a systems biology approach to understanding the critical role of blood, bone marrow, and vascular endothelium in animal and human organs and organisms. It also applies fundamental genetic, proteomic, and metabolomic tools to better understand hematologic physiology and pathophysiology. View funding information for the Molecular Cellular and Systems Blood Science Branch.
        
            Contact:
    Allison Gillaspy
                            Ph.D.
                            Branch Chief
                            allison.gillaspy@nih.gov
                                                                                                
        Translational Blood Science and Resources Branch
    The Translational Blood Science and Resources Branch supports the creation of blood-focused therapeutics development and manufacturing, the facilitation and promotion of discovery science from bench to first-in-human studies, and the coordination of workforce development and opportunities for small-business programs. This emphasis includes the oversight, support, and stimulation of post-discovery science, preclinical research, early phase clinical studies and trials, and commercialization initiatives (the Small Business Innovation Research and Small Business Technology Transfer programs) in blood sciences. This Branch also administers and serves as liaison for NHLBI resources related to translational research. View funding information for the Translational Blood Science and Resources Branch.
        
            Contact:
    Traci Heath Mondoro
                            Ph.D.
                            Branch Chief
                            mondorot@nhlbi.nih.gov
                                                                                                
        Office of the Director
    The Office of the Director oversees all Divisional activities. This includes planning and coordinating the activities of all Branches responsible for supporting and managing discovery, translational, and clinical research programs across the blood sciences; continuously assessing the Institute's national and international health programs related to all blood science disciplines and resources; fostering and coordinating interdivisional, trans-NHLBI, trans-NIH and interagency collaborative and cooperative research arrangements; developing and maintaining the necessary scientific management capability in the Division to foster and guide effective programs in blood sciences and resources management; planning, coordinating, and directing special activities that transcend program lines, including minority, small business, and education research programs; providing program analysis and administrative support services for the Division; and overseeing Divisional programs to support the workforce in nonmalignant hematology.
                                    Related Scientific Focus Areas
                        
      Blood Disorders and Blood Safety
            
                        
            
                                RELATED NEWS
exterior of Rural Heart and Lung Study's mobile exam unit
              January 04, 2024|
						Research Feature
                                    	
	A High-tech Research Clinic on Wheels
	

        
        NHLBI study assesses health of residents in rural South for heart, lung disease Adults in the rural South region, which includes Appalachia and the Mississippi Delta, have some of the highest rates of heart disease, obesity, high blood pressure, and chronic obstructive pulmonary disease (COPD) in the country. Heart failure rates, for example, are...
                                            							View more news on 
				
Division of Blood Diseases and Resources
                                    RELATED EVENT
two men walk together outside
              Building a More Diverse, Equitable, and Inclusive Blood Donor Community
	

        
    
                						March 19, 2024

				Virtual via Facebook 
12:00 p.m. ET

                                                              	
            Join blood health experts for a conversation about the new recommendations for screening for all blood donors and how it may help to incr...

                      
        
                                                							View more events on 
				
Division of Blood Diseases and Resources
                                                    Contact 
Division of Blood Diseases and Resources
                        
                        
    Postal Mail
                                                                                            
            The National Heart, Lung and Blood InstituteTwo Rockledge Center, Suite 90306701 Rockledge Dr. MSC 7950Bethesda, MD 20892-7950United States
                                                                
                    Phone
                            
            1-301-435-0080
                                                                
                    Twitter
                                                                                        Follow us on Twitter:
            @NHLBI_BLOODDir Back To Top Link
  

        

        Back to top
  Web Policies & Notices
  

        

              Accessibility
                      No FEAR Act Data
                      Privacy Policy
                      Freedom of Information Act (FOIA)
                      HHS Vulnerability Disclosure
    
          Related Government Websites
  

        

              Health and Human Services
                      National Institutes of Health
                      Office of the Inspector General
                      USA.gov
    
          Stay Connected
    
      
            chat bubblesLive ChatLive Chat with us, Monday through Friday, 8:30 a.m. to 5:00 p.m. EST.envelopeGet Email AlertsReceive automatic alerts about NHLBI related news and highlights from across the Institute.
  Footer Bottom
  

        



Contact Us
                            Site Index
                            Jobs