Amended and Restated Registration Rights Agreement



 EXHIBIT 10.11 
 AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT 
 THIS AMENDED AND RESTATED REGISTRATION
RIGHTS AGREEMENT (this “Agreement”), dated as of June 5, 2007, is made and entered into by and among VIA PHARMACEUTICALS, INC., a Delaware corporation (the “Company”), and each of the stockholders of the
Company listed on Exhibit A hereto, as such Exhibit A may be amended from time to time (the “Stockholders”). For the purposes of this Agreement, the term “Company” shall be deemed to include and refer to any
successor in interest to the Company, whether by means of statutory conversion, merger, consolidation, recapitalization, reorganization or otherwise. 
 R E C I T A L S 
 WHEREAS, the parties hereto are party to that certain Registration Rights
Agreement, dated as of March 31, 2006 (the “Original Registration Rights Agreement”), pursuant to which the Company has agreed to provide the signatories hereto with certain registration rights under the Securities Act and
applicable state securities laws; 
 WHEREAS, the Company has entered into that certain Agreement and Plan of Merger, dated as of
February 7, 2007 (the “Merger Agreement”), by and among the Company, Corautus Genetics Inc., a Delaware corporation (“Corautus”), and Resurgens Merger Corp., a Delaware corporation and a wholly-owned subsidiary
of Corautus (“Resurgens”); 
 WHEREAS, pursuant to the terms of the Merger Agreement, at the Effective Time (as defined in
the Merger Agreement), Resurgens will merge with and into the Company (the “Merger”) and the Company will be the surviving corporation and become a wholly-owned subsidiary of Corautus; 
 WHEREAS, at the Effective Time (as defined in the Merger Agreement) of the Merger, pursuant to the terms of the Merger Agreement, all outstanding shares
of Common Stock and Series A Preferred Stock of the Company will automatically be converted into the right to receive shares of common stock, par value $0.001 per share, of Corautus (“Corautus Common Stock”), and all outstanding
options to purchase shares of VIA Common Stock that have not been exercised prior to the consummation of the Merger will be assumed by Corautus and become options to purchase shares of Corautus Common Stock; 
 WHEREAS, immediately following the consummation of the Merger, Corautus will change its name to “VIA Pharmaceuticals, Inc.”; and 
 WHEREAS, in connection with the Merger, the parties hereto desire to amend and restate the Original Registration Rights Agreement in its entirety
pursuant to the terms and conditions contained in this Agreement. 







 NOW, THEREFORE, in consideration of the recitals and the mutual premises, covenants and agreements
contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 
 1. Definitions. In addition to capitalized terms defined elsewhere in this Agreement, the following capitalized terms shall have the following meanings when used in this Agreement: 
 “Business Day” means each day other than a Saturday, a Sunday or any other day on which banking institutions in the city of San
Francisco, California are authorized or obligated by law or executive order to be closed. 
 “Commission” means the
Securities and Exchange Commission and any successor agency performing comparable functions. 
 “Common Stock” means the
common stock, par value $0.001 per share, of the Company. 
 “Exchange Act” means the Securities Exchange Act of 1934, as
amended, or any successor federal statute, and the rule and regulations of the Commission thereunder, as the same shall be in effect from time to time. 
 “Immediate Family Member” means with respect to any holder of Registrable Securities, the parents, siblings, spouse and issue, spouses of issue and any trust for the benefit of, or the legal
representative of, any of the preceding Persons, or any partnership substantially all of the partners of which are one or more of such Persons or the holder of Registrable Securities or any limited liability company substantially all of the members
of which are one or more of such Persons or the holder of Registrable Securities. 
 “Person” means an individual,
partnership, corporation, limited liability company, association, joint stock company, trust, joint venture, unincorporated organization or other entity, or a governmental entity or any department, agency or political subdivision thereof.

 “Public” means a corporation that has a class of securities registered pursuant to Section 12 of the Exchange Act or
which is required to file reports pursuant to Section 15(d) of the Exchange Act. 
 “Public Offering” means any
offering by the Company of its equity securities to the public pursuant to an effective registration statement under the Securities Act or any comparable statement under any comparable federal statute then in effect (other than any registration
statement on Form S-8 or Form S-4 or any successor forms thereto). 
 “Qualified IPO” means a firm commitment underwritten
public offering of Common Stock of the Company that yields net proceeds to the Company of not less than $20,000,000 at an equivalent price per share of Common Stock of not less than $3.00 (as adjusted for any stock splits, stock dividends, in-kind
equity distributions and recapitalizations). 
  

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 “Registrable Securities” means at any time, any of the following owned by any equity
holder of the Company party to this Agreement: (i) Common Stock or other equity securities of the Company into which the Common Stock then outstanding shall be reclassified or changed, including by reason of a merger, consolidation,
reorganization, recapitalization or statutory conversion (including, without limitation, Corautus Common Stock) which are then owned by any Stockholder, including any other Person who is a permitted transferee or assignee of such holder pursuant to
Section 13 hereof; (ii) the Series A Registrable Securities; and (iii) any common equity securities of the Company then outstanding which were issued as, or were issued directly or indirectly upon the conversion, exchange or
exercise of other equity securities issued or issuable as a dividend, stock split or other distribution with respect or in replacement of any equity securities referred to in (i) or (ii) of this definition; provided, however, that
Registrable Securities shall not include any equity securities which have been registered pursuant to the Securities Act or which have been sold to the public pursuant to Rule 144 of the Commission under the Securities Act. 
 “Securities Act” means the Securities Act of 1933, as amended, or any successor federal statute, and the rule and regulations of the
Commission thereunder, as the same shall be in effect from time to time. 
 “Series A Registrable Securities” means at any
time, any of the following owned by any equity holder of the Company party to this Agreement: (i) any common equity securities of the Company issuable upon conversion or exchange of the Series A Preferred Stock, or issuable or issued upon
conversion or exchange of other equity securities of the Company into which the Series A Preferred Stock shall be reclassified or changed, including by reason of a merger, consolidation, reorganization, recapitalization or statutory conversion then
outstanding (including, without limitation, Corautus Common Stock) which are then owned by any Stockholder, including any other Person who is a permitted transferee or assignee of such holder pursuant to Section 13 hereof; and
(ii) any common equity securities of the Company then outstanding which were issued as, or were issued directly or indirectly upon the conversion, exchange or exercise of other equity securities issued or issuable as a dividend, stock split or
other distribution with respect or in replacement of any equity securities referred to in (i) of this definition. 
 “Series A
Preferred Stock” means the Series A convertible preferred stock, par value $0.001 per share, of the Company. 
 “Stockholder
Agreement” means that certain First Amended and Restated Stockholders’ Agreement, dated of even date herewith, among the Company and each of the holders of shares of the Company’s capital stock signatory thereto, as amended from
time to time. 
 2. Demand Registration. 
 2.1 Long-Form Registrations. 
 (a) Subject to the terms of this Agreement, at any time after 180
days following the effective date of a Qualified IPO or the Company becoming Public (as a result of 
  

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 the Merger or otherwise), the holders of at least a majority of the Series A Registrable Securities may request
registration under the Securities Act of all or part of their then outstanding Registrable Securities represented by such Series A Registrable Securities on Form S-1 or any similar long-form registration; provided, that with respect to any
demands under this clause (a) the anticipated aggregate offering price of the Registrable Securities covered by such registration exceeds $2,000,000 (net of underwriting discounts and commissions). 
 (b) Within ten (10) days after receipt of any written request pursuant to this Section 2.1, the Company will give written notice of
such request to all other holders of Registrable Securities and will use its reasonable best efforts to include in such registration all Registrable Securities with respect to which the Company has received written requests for inclusion within 20
days after delivery of the Company’s notice, and, thereupon the Company will use its reasonable best efforts to file as soon as practicable, and in any event within 90 days of the receipt of such request, a registration statement under the
Securities Act covering all Registrable Securities requested to be included in such registration. All registrations requested pursuant to this Section 2.1 are referred to herein as “Long-Form Demand Registration.” The
Company shall not be obligated to effect, or to take any action to effect, more than one (1) Long-Form Demand Registration pursuant to this Section 2.1. In addition, the Company shall not be obligated to effect, or to take any
action to effect, any Long-Form Demand Registration during (i) the period starting with the date 90 days prior to the Company’s good faith estimate of the date of filing of, and ending on a date 90 days after the effective date of, a
registration subject to Section 4 hereof; provided, that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective; and (ii) the 180-day period following
the Company being Public (as a result of the Merger or otherwise). 
 2.2 Short-Form Registrations. In addition to the Long-Form
Demand Registration provided pursuant to Section 2.1 above, commencing the date on which the Company becomes eligible to register securities issued by it on a Form S-3 or any similar short-form registration, the holders of at least
twenty-five percent (25%) of the Registrable Securities then outstanding will be entitled to request registrations under the Securities Act of all or part of their Registrable Securities on Form S-3, if available to the Company, or any similar
short-form registration (“Short-Form Demand Registrations” and, together with the Long-Form Demand Registration, “Demand Registrations”); provided, however, that the anticipated aggregate offering amount of
the Registrable Securities included in any such Short-Form Registration exceeds $1,000,000. Promptly after receipt of any request pursuant to this Section 2.2, the Company will give written notice of such request to all other holders of
Registrable Securities and will use reasonable best efforts to include in such registration all Registrable Securities with respect to which the Company has received written requests for inclusion within 15 days after delivery of the Company’s
notice. Once the Company has become subject to the reporting requirements of the Exchange Act, the Company will use its reasonable best efforts to make Short-Form Demand Registrations available for the sale of Registrable Securities. Demand
Registrations will be Short-Form Demand Registrations whenever the Company is permitted to use any applicable short form. If a Short-Form Demand Registration is to be an underwritten Public Offering, and if the underwriters for marketing or other
reasons request the inclusion in the registration statement of information which is not required under the Securities Act to be included in a registration statement on the applicable form for the Short-Form Demand Registration, the Company will
provide such information as may be reasonably requested for 
  

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 inclusion by the underwriters in the Short-Form Demand Registration. The Company shall not be obligated to effect more
than two (2) Short-Form Demand Registrations in any twelve month period pursuant to this Section 2.2. 
 2.3 Payment of
Expenses for Demand Registrations. The Company will pay all Registration Expenses (as defined in Section 7 below) for the Demand Registrations permitted under Sections 2.1 and 2.2 (other than underwriting discounts and
commissions incurred by each holder of the Company’s securities participating in the registration). A registration will not count as a Demand Registration (i) unless a registration statement with respect thereto has become effective and
remained effective in compliance with the provisions of the Securities Act with respect to the disposition of all Registrable Securities covered by such registration statement until the earlier of (x) such time as all of such Registrable
Securities have been disposed of in accordance with the intended methods of disposition by the seller or sellers thereof set forth in such registration statement and (y) 120 days after the effective date of such registration statement,
(ii) if after it has become effective, such registration is interfered with by any stop order, injunction or other order or requirement of the Commission or other governmental agency or court for any reason not attributable to the selling
holders and has not thereafter become effective, or (iii) if the conditions to closing specified in the underwriting agreement, if any, entered into in connection with such registration are not satisfied or waived, other than by reason of a
failure on the part of the holders of the Registrable Securities to be registered thereunder. 
 2.4 Priority. If a Demand
Registration is an underwritten Public Offering and the managing underwriters advise the Company in writing that in their opinion the inclusion of the number of Registrable Securities and other securities requested to be included exceeds the number
of securities which can be sold in the offering without adversely affecting the marketability of such offering, then the managing underwriter may exclude securities (including Registrable Securities) from the registration and the underwriting and
the number of securities that may be included in such registration and underwriting shall include first, the Series A Registrable Securities requested to be included in such registration, pro rata among the holders of such Series A
Registrable Securities on the basis of the total number of Series A Registrable Securities owned by each such holder, second, the Registrable Securities (other than the Series A Registrable Securities) requested to be included in such
registration, pro rata among the holders of such Registrable Securities on the basis of the total number of Registrable Securities owned by each such holder, and third, other equity securities requested to be included in such registration to
be allocated pro rata among the holders of thereof on the basis of the number of such equity securities owned by each such holder. In no event will a Demand Registration pursuant to Section 2.1 count as a Long-Form Demand Registration
for purposes of Section 2.1 unless at least thirty percent (30%) of all Registrable Securities requested to be registered in such Demand Registration by the initiating holders are, in fact, registered and sold in such registration.

 2.5 Restrictions. Except as contemplated by Section 2.2 hereof, the Company will not be obligated to effect any Demand
Registration within 180 days after the effective date of a previous Demand Registration. With respect to any Demand Registration, if (a) the Board of Directors of the Company reasonably and in good faith determines that such filing would be
seriously detrimental to the Company or its stockholders, or require a disclosure of a material 
  

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 fact that might reasonably be expected to have a material adverse effect on the Company or any plan or proposal by the
Company or any of its subsidiaries to engage in any acquisition or disposition of assets or equity securities (other than in the ordinary course of business) or any merger, consolidation, tender offer, material financing or other significant
transaction and (b) the Company shall furnish the holders of Registrable Securities who have requested a Demand Registration a certificate signed by an executive officer of the Company to such effect, the Company may postpone for up to 120 days
the filing or the effectiveness of a registration statement for a Demand Registration; provided, that the Company may not postpone the filing or effectiveness of a registration statement for a Demand Registration for more than 120 days during
any 12-month period. 
 2.6 Selection of Underwriters. The holders of a majority of the Registrable Securities initiating the Demand
Registration shall have the right to select the investment banker(s) and manager(s) to administer the offering, subject to the Company’s approval which will not be unreasonably withheld or delayed. 
 3. Shelf Registration. 
 3.1 Right
to Shelf Registration. Subject to the terms of this Agreement, at any time after 180 days following the effective date of a Qualified IPO or the Company becoming Public (as a result of the Merger or otherwise), the holders of at least a majority
of the Series A Registrable Securities shall be entitled to request that the Company file a shelf registration statement with respect to all or part of their Registrable Securities represented by such Series A Registrable Securities pursuant to Rule
415 under the Securities Act (the “Shelf Registration”). The Company shall use its reasonable best efforts to have the Shelf Registration declared effective as soon as practicable after such filing, and shall use its reasonable best
efforts to keep the Shelf Registration effective and updated, from the date such Shelf Registration is declared effective until the earliest to occur of (a) such time as the holder requesting the Shelf Registration has sold all of its
Registrable Securities registered pursuant to the Shelf Registration, and (b) two (2) years from the date such Shelf Registration is declared effective (such period, the “Shelf Registration Effectiveness Period”). The
Company shall not be obligated to effect, or to take any action to effect, more than one (1) Shelf Registration pursuant to this Section 3.1. In addition, the Company shall not be obligated to effect, or to take any action to
effect, any Shelf Registration during (i) the period starting with the date 90 days prior to the Company’s good faith estimate of the date of filing of, and ending on a date 90 days after the effective date of, a registration subject to
Section 4 hereof; provided, that the Company is actively employing in good faith all reasonable efforts to cause such registration statement to become effective; and (ii) the 180-day period following the Company being Public
(as a result of the Merger or otherwise). 
 3.2 Payment of Expenses for Shelf Registration. The Company will pay all Registration
Expenses (as defined in Section 7 below) for the Shelf Registration permitted under Section 3.1 (other than underwriting discounts and commissions incurred by each holder of the Company’s securities participating in the
registration). A registration will not count as a Shelf Registration (i) unless a registration statement with respect thereto has become effective and remained effective in compliance with the provisions of the Securities Act with respect to
the disposition of all Registrable Securities covered by such registration statement until the earlier of (x) such time as all of such Registrable Securities have been disposed of in accordance with the 
  

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 intended methods of disposition by the seller or sellers thereof set forth in such registration statement and (y) 90
days after the effective date of such registration statement, (ii) if after it has become effective, such registration is interfered with by any stop order, injunction or other order or requirement of the Commission or other governmental agency
or court for any reason not attributable to the selling holders and has not thereafter become effective, or (iii) if the conditions to closing specified in the underwriting agreement, if any, entered into in connection with such registration
are not satisfied or waived, other than by reason of a failure on the part of the holders of the Registrable Securities to be registered thereunder. 
 3.3 Restrictions. With respect to any Shelf Registration, if (a) the Board of Directors of the Company reasonably and in good faith determines that such filing would be seriously detrimental to the Company
or its stockholders, or require a disclosure of a material fact that might reasonably be expected to have a material adverse effect on the Company or any plan or proposal by the Company or any of its subsidiaries to engage in any acquisition or
disposition of assets or equity securities (other than in the ordinary course of business) or any merger, consolidation, tender offer, material financing or other significant transaction and (b) the Company shall furnish the holders of Series A
Registrable Securities who have requested a Shelf Registration a certificate signed by an executive officer of the Company to such effect, the Company may postpone for up to 120 days the filing or the effectiveness of a registration statement for a
Shelf Registration; provided, that the Company may not postpone the filing or effectiveness of a registration statement for a Shelf Registration for more than 180 days during any 12-month period. 
 4. Piggyback Registration. 
 4.1
Right to Piggyback. At any time following a Qualified IPO or the Company becoming Public (as a result of the Merger or otherwise), whenever the Company proposes to register any of its equity securities (or securities that are convertible into
equity securities) under the Securities Act for its own account or otherwise, and the registration form to be used may be used for the registration of any Registrable Securities (a “Piggyback Registration”) (except for the
registrations on Form S-8 or Form S-4 or any successor form thereto), the Company will promptly give written notice to all holders of the Registrable Securities of its intention to effect such a registration and will use reasonable best efforts to
include in such registration all Registrable Securities (in accordance with the priorities set forth in Sections 4.2 and 4.3 below) with respect to which the Company has received written requests for inclusion specifying the number of
equity securities desired to be registered, which request shall be delivered within 20 days after the delivery of the Company’s notice; provided, that with respect to any Piggyback Registration, the holders of a majority of Registrable
Securities shall have the right to waive and forego, as against themselves and all other holders of Registrable Securities, the right to include any Registrable Securities in such Piggyback Registration. 
 4.2 Priority on Primary Registrations. If a Piggyback Registration is an underwritten primary registration on behalf of the Company and the
managing underwriters advise the Company in writing that in their opinion the number of securities requested to be included in the registration exceeds the number which can be sold in such offering without adversely affecting the marketability of
such offering, then the managing underwriter may exclude securities (including Registrable Securities) from the registration and the underwriting, 
  

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 and the number of securities that may be included in such registration and underwriting shall include first, any
securities that the Company proposes to sell, second, the Series A Registrable Securities requested to be included in such registration, pro rata among the holders of such Series A Registrable Securities on the basis of the total number of
Registrable Securities owned by each such holder, third, the Registrable Securities (other than the Series A Registrable Securities) requested to be included in such registration, pro rata among the holders of such Registrable Securities on
the basis of the total number of Registrable Securities owned by each such holder, and fourth, other equity securities requested to be included in such registration to be allocated pro rata among the holders thereof on the basis of the number
of such equity securities owned by each such holder. 
 4.3 Priority on Secondary Registrations. If a Piggyback Registration is an
underwritten secondary registration on behalf of holders of the Company’s securities and the managing underwriters advise the Company in writing that in their opinion the number of securities requested to be included in the registration exceeds
the number which can be sold in such offering without adversely affecting the marketability of such offering, the Company will include in such registration first, the equity securities requested to be included therein by the holders
requesting such registration and the Series A Registrable Securities requested to be included in such registration, pro rata among the holders of such equity securities and Series A Registrable Securities on the basis of the total number of equity
securities and Series A Registrable Securities owned by each such holder, second, the Registrable Securities (other than the Series A Registrable Securities) requested to be included in such registration, pro rata among the holders of such
Registrable Securities on the basis of the total number Registrable Securities owned by each such holder, and third, other equity securities requested to be included in such registration to be allocated pro rata among the holders thereof on
the basis of the number of such equity securities owned by each such holder. 
 4.4 Other Registrations. If the Company has previously
filed a registration statement with respect to Registrable Securities pursuant to this Section 4, and if such previous registration has not been withdrawn or abandoned, the Company will not file or cause to be effected any other
registration of any of its equity securities or securities convertible or exchangeable into or exercisable for its equity securities under the Securities Act (except on Form S-8 or Form S-4 or any successor forms thereto), whether on its own behalf
or at the request of any holder or holders of such securities, until a period of at least 180 days has elapsed from the effective date of such previous registration. 
 4.5 Selection of Underwriters. In connection with any Piggyback Registration, the Company will have such right to select the managing underwriters (subject to the approval of the holders of a majority of the
Registrable Securities requested to be included in such registration, which approval shall not be unreasonably withheld or delayed). 
 5.
Lock-Up Agreements. 
 5.1 Holders’ Agreements. To the extent not inconsistent with applicable law, each holder of
Registrable Securities agrees that upon request of the Company or the underwriters managing any underwritten offering of the Company’s securities, it will (a) not sell, make any short sale of, loan, grant any option for the purchase of,
otherwise dispose of, hedge or 
  

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 transfer any of the economic interest in (or agree or commit to do any of the foregoing) any Registrable Securities
(other than those included in the registration, if any) without the prior written consent of the Company or such underwriters, as the case may be, (i) for up to 14 days prior to, and during the 90-day period following, the effective date of a
registration statement of the Company filed under the Securities Act; and (ii) for the 180-day period following the Company becoming Public (as a result of the Merger or otherwise); and (b) enter into and be bound by such form of agreement
with respect to the foregoing as the Company or such managing underwriter may reasonably request; provided that each officer and director and each third party who holds 5.0% or more of the outstanding equity securities of the Company also agrees to
such restrictions. Notwithstanding anything to the contrary contained in this Section 5.1, if (i) during the last 17 days of the initial lock-up period described above, the Company releases earnings results or announces material
news or a material event or (ii) prior to the expiration of the initial lock-up period, the Company announces that it will release earnings results during the 15-day period following the last day of the initial lock-up period, then in each case
the lock-up period described above will be automatically extended until the expiration of the 18-day period beginning on the date of release of the earnings results or the announcement of the material news or material event, as applicable, unless
the managing underwriters waive, in writing, such extension. Nothing herein shall prevent a holder of Registrable Securities from transferring Registrable Securities to a permitted transferee as provided for in Section 7 of the
Stockholders Agreement; provided, that any transferees of such Registrable Securities agrees to be bound by the provisions of this Agreement to the extent the transferor would be so bound. 
 5.2 Company’s Agreements. The Company agrees not to effect, and, to the extent not inconsistent with applicable laws, to cause each holder of
its equity securities purchased from the Company at any time after the date of this Agreement (except in a registered public offering) not to effect, any public sale or distribution of its equity securities, or any securities convertible into or
exchangeable or exercisable for such securities, (i) during the 90-day period following, the effective date of a registration statement of the Company filed under the Securities Act; or (ii) during the 180-day period following the Company
becoming Public (as a result of the Merger or otherwise)(in each case except as part of any such underwritten registration or pursuant to registrations on Form S-8 or Form S-4 or any successor forms thereto), unless the underwriters managing the
Public Offering otherwise agree. 
 6. Registration Procedures. Whenever the holders of Registrable Securities have requested that any
Registrable Securities be registered pursuant to this Agreement, the Company will use its reasonable best efforts to effect the registration and sale of such Registrable Securities in accordance with the intended method of disposition thereof and,
pursuant thereto, the Company will as expeditiously as possible: 
 (a) prepare and, as soon as practicable after the end of the period
within which requests for registration may be given to the Company, file with the Commission a registration statement with respect to such Registrable Securities and use its reasonable best efforts to cause such registration statement to become
effective (provided that before filing a registration statement or prospectus, or any amendments or supplements thereto, the Company will furnish copies of all such documents proposed to be filed to one counsel designated by holders of a majority of
the Registrable Securities covered by such registration statement); 
  

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 (b) prepare and file with the Commission such amendments and supplements to such registration statement
and the prospectus(es) used in connection therewith as may be necessary to keep such registration statement effective for a period of not less than 120 days, and comply with the provisions of the Securities Act with respect to the disposition of all
securities covered by such registration statement during such period in accordance with the intended methods of disposition by the sellers thereof set forth in such registration statement; 
 (c) furnish to each seller of Registrable Securities such number of copies of such registration statement, each amendment and supplement thereto, the
prospectus(es) included in such registration statement (including each preliminary prospectus) and such other documents as such seller may reasonably request in order to facilitate the disposition of the Registrable Securities owned by such seller;

 (d) use its reasonable best efforts to register or qualify such Registrable Securities under such other securities or blue sky laws of
such jurisdictions as Investor reasonably requests and do any and all other acts and things which may be reasonably necessary or advisable to enable such seller to consummate the disposition in such jurisdictions of the Registrable Securities owned
by such seller (provided that the Company will not be required to (i) qualify generally to do business in any jurisdiction where it would not otherwise be required to qualify but for this subparagraph, (ii) consent to general service of
process in any such jurisdiction, or (iii) subject it to taxation in any such jurisdiction); 
 (e) promptly notify each seller of such
Registrable Securities, at any time when a prospectus relating thereto is required to be delivered under the Securities Act, of the happening of any event as a result of which the prospectus included in such registration statement contains an untrue
statement of a material fact or omits any fact necessary to make the statements therein not misleading in the light of the circumstances under which they were made, and, at the request of any such seller, the Company will prepare a supplement or
amendment to such prospectus so that, as thereafter delivered to the purchasers of such Registrable Securities, such prospectus will not contain any untrue statement of a material fact or omit to state any fact necessary to make the statements
therein not misleading in the light of the circumstances under which they were made; 
 (f) cause all such Registrable Securities to be
listed on each securities exchange on which similar securities issued by the Company are then listed or if no such securities are then listed, such securities exchange as the holders of a majority of the Registrable Securities included in such
registration may request; 
 (g) provide a transfer agent, registrar and CUSIP number for all such Registrable Securities not later than the
effective date of such registration statement; 
 (h) enter into such customary agreements (including underwriting agreements in customary
form) and take all such other customary actions as the holders of a majority of the Registrable Securities being sold or the underwriters, if any, reasonably request in order to expedite or facilitate the disposition of such Registrable Securities;

  

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 (i) make available for inspection by any seller of Registrable Securities, any underwriter participating
in any disposition pursuant to such registration statement, and any attorney, accountant or other agent retained by any such seller or underwriter, all financial and other records, pertinent corporate documents and properties of the Company, and
cause the Company’s officers, directors, employees and independent accountants to supply all information reasonably requested by any such seller, underwriter, attorney, accountant or agent in connection with such registration statement;
provided, however, that any records, information or documents that are furnished by the Company and that are non-public shall be used only in connection with such registration and shall be kept strictly confidential by any seller of
Registrable Securities except to the extent disclosure of such records, information or documents is required by written order of a court or other governmental authority having jurisdiction; 
 (j) advise each seller of such Registrable Securities, promptly after it shall receive notice or obtain knowledge thereof, of the issuance of any stop
order by the Commission suspending the effectiveness of such registration statement or the initiation or threatening of any proceeding for such purpose and promptly use its best efforts to prevent the issuance of any stop order or to obtain its
withdrawal if such stop order should be issued; 
 (k) at least 48 hours prior to the filing of any registration statement or prospectus, or
any amendment or supplement to such registration statement or prospectus, furnish a copy thereof to each seller of such Registrable Securities and refrain from filing any such registration statement, prospectus, amendment or supplement to which
counsel selected by the holders of a majority of the Registrable Securities being registered shall have reasonably objected on the grounds that such document does not comply in all material respects with the requirements of the Securities Act or the
rules and regulations thereunder, unless, in the case of an amendment or supplement, in the opinion of counsel for the Company the filing of such amendment or supplement is reasonably necessary to protect the Company from any liabilities under any
applicable federal or state law and such filing will not violate applicable laws; 
 (l) at the request of any seller of such Registrable
Securities in connection with an underwritten offering, furnish on the date or dates provided for in the underwriting agreement: (i) an opinion of counsel, addressed to the underwriters and the sellers of Registrable Securities, covering such
matters as such counsel, underwriters and the sellers may reasonably agree upon, including such matters as are customarily furnished in connection with an underwritten offering, and (ii) a letter or letters from the independent certified public
accountants of the Company addressed to the underwriters and the sellers of Registrable Securities, covering such matters as such accountants, underwriters and sellers may reasonably agree upon, in which letter(s) such accountants shall state,
without limiting the generality of the foregoing, that they are independent certified public accountants within the meaning of the Securities Act and that in their opinion the financial statements and other financial data of the Company included in
the registration statement, the prospectus(es), or any amendment or supplement thereto, comply in all material respects with the applicable accounting requirements of the Securities Act; and 
 (m) make senior executives of the Company reasonably available to assist the underwriters with respect to, and accompany the underwriters on, the
so-called “road show” in connection with the marketing efforts for, and the distribution and sale of Registrable Securities pursuant to a registration statement. 
  

 11 








 7. Registration Expenses. 
 7.1 Company’s Expenses. All expenses incident to the Company’s performance of or compliance with this Agreement, including, but not
limited to, all registration and filing fees, fees and expenses of compliance with securities or blue sky laws, printing expenses, messenger and delivery expenses, fees and expenses incurred in connection with any “road show,” and fees and
disbursements of counsel for the Company, reasonable fees and disbursements of one counsel chosen by the holders of a majority of the Registrable Securities included in such registration to represent all holders of Registrable Securities included in
any registration and all independent certified public accountants, underwriters (excluding underwriting discounts and selling commissions) and other Persons retained by the Company (all such expenses being herein called “Registration
Expenses”), will be borne by the Company. In addition, the Company will pay its internal expenses (including, but not limited to, all salaries and expenses of its officers and employees performing legal or accounting duties), the expense of
any annual audit or quarterly review, the expense of any liability insurance obtained by the Company and the expenses and fees for listing the securities to be registered on each securities exchange; provided, however, that if a request for
Demand Registration is subsequently withdrawn at the request of a majority of the holders of Registrable Securities requested to be registered, the holders of Registrable Securities who have withdrawn such request for Demand Registration shall
forfeit such Demand Registration unless the holders of Registrable Securities to be registered pay (or reimburse the Company) for all of the Registration Expenses with respect to such withdrawn registration; provided, further, that if at the
time of such withdrawal, the holders (A) have learned of a material adverse change in the condition, business or prospects of the Company that was not known to the holders at the time of their request and (B) have withdrawn the request
with reasonable promptness following disclosure by the Company of such material adverse change, then the holders shall not be required to pay any of such Registration Expenses and shall not forfeit their Demand Registration. 
 7.2 Holder’s Expenses. To the extent that any expenses incident to any registration are not required to be paid by the Company, each holder
of Registrable Securities included in a registration will pay all such expenses which are clearly and solely attributable to the registration of such holder’s Registrable Securities so included in such registration, and any other expenses not
so attributable to one holder will be borne and paid by all sellers of securities included in such registration in proportion to the number of securities so included by each such seller. 
 8. Indemnification. 
 8.1 By the
Company. The Company agrees to indemnify, to the extent permitted by law, each holder of Registrable Securities, its members, managers, officers, employees and directors and each Person who controls such holder (within the meaning of the
Securities Act) against all losses, claims, damages, liabilities and expenses (including, but not limited to, attorneys’ fees and expenses) caused by any untrue or alleged untrue statement of material fact contained in any registration
statement, prospectus or preliminary prospectus, or 
  

 12 








 any amendment thereof or supplement thereto, or any omission or alleged omission of a material fact required to be stated
therein or necessary to make the statements therein not misleading, except insofar as the same are caused by or contained in any information furnished in writing to the Company by such holder expressly for use therein or by such holder’s
failure to deliver a copy of the prospectus or any amendments or supplements thereto after the Company has furnished such holder with a sufficient number of copies of the same. In connection with an underwritten offering, the Company will indemnify
such underwriters, their officers and directors and each Person who controls such underwriters (within the meaning of the Securities Act) to the same extent as provided above with respect to the indemnification of the holders of Registrable
Securities. The payments required by this Section 8.1 will be made periodically during the course of the investigation or defense, as and when bills are received or expenses incurred. Notwithstanding anything to the contrary contained
herein, the indemnity agreement contained in this Section 8.1 shall not apply to amounts paid in settlement of any such loss, claim, damage, liability, or action if such settlement is effected without the consent of the Company (which
consent shall not be unreasonably withheld), nor shall the Company be liable to any holder of Registrable Securities, underwriter or controlling Person for any such loss, claim, damage, liability, expenses or action to the extent that it arises out
of or is based upon an untrue statement or omission that is contained in or omitted from any information so furnished in writing by such holder, underwriter or controlling Person for the acknowledged purpose of inclusion in such registration
statement, prospectus or preliminary prospectus. 
 8.2 By Each Holder of Registrable Securities. In connection with any registration
statement in which a holder of Registrable Securities is participating, each such holder will furnish to the Company in writing such information as is reasonably necessary for use in connection with any such registration statement or prospectus and,
to the extent permitted by law, will indemnify the Company, its members, managers, directors, employees and officers and each Person who controls the Company (within the meaning of the Securities Act) against any losses, claims, damages, liabilities
and expenses resulting from any untrue or alleged untrue statement of material fact contained in the registration statement, prospectus or preliminary prospectus, or any amendment thereof or supplement thereto, or any omission or alleged omission of
a material fact required to be stated therein or necessary to make the statements therein not misleading, but only to the extent that such untrue statement or omission is contained in or omitted from any information so furnished in writing by such
holder for the acknowledged purpose of inclusion in such registration statement, prospectus or preliminary prospectus; provided that the obligation to indemnify will be several, not joint and several, among such holders of Registrable Securities and
the liability of each such holder of Registrable Securities will be in proportion to and limited in all events to the gross proceeds received by such holder from the sale of Registrable Securities pursuant to such registration statement, except in
the case of willful fraud. Notwithstanding anything to the contrary contained herein, the indemnity agreement contained in this Section 8.2 shall not apply to amounts paid in settlement of any such loss, claim, damage, liability, or
action if such settlement is effected without the consent of the Company (which consent shall not be unreasonably withheld). 
 8.3
Procedure. Each party entitled to indemnification under this Section 8 (the “Indemnified Party”) shall give written notice to the party required to provide indemnification (the “Indemnifying
Party”) promptly after such Indemnified Party has received written notice of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party to 
  

 13 








 assume the defense of any such claim or any litigation resulting therefrom, provided such counsel for the Indemnifying
Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld or delayed). The Indemnified Party may participate in such defense at such Indemnified
Party’s expense; provided, however, that the Indemnifying Party shall bear the expense of such defense of the Indemnified Party if (i) the Indemnifying Party has agreed in writing to pay such expenses, (ii) the Indemnifying
Party shall have failed to assume the defense of such claim or employ counsel reasonably satisfactory to the Indemnified Party, or (iii) in the reasonable judgment of the Indemnified Party, based upon the written advice of such Indemnified
Party’s counsel, representation of both parties by the same counsel would be inappropriate due to actual or potential conflicts of interest; provided, however, that in no event shall the Indemnifying Party be liable for the fees and
expenses of more than one counsel (excluding one local counsel per jurisdiction as necessary) for all Indemnified Parties in connection with any one action or separate but similar or related actions in the same jurisdiction arising out of the same
event, allegations or circumstances. The Indemnified Party shall not make any settlement without the prior written consent of the Indemnifying Party, which consent shall not be unreasonably withheld or delayed. The failure of any Indemnified Party
to give notice as provided herein shall relieve the Indemnifying Party of its obligations under this Section 8 only to the extent that such failure to give notice shall materially adversely prejudice the Indemnifying Party in the defense
of any such claim or any such litigation. No Indemnifying Party, in the defense of any such claim or litigation, shall, except with the prior written consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement
(A) which does not include as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect to such claim or litigation in form and substance reasonably satisfactory
to such Indemnified Party or (B) which includes an admission of fault, culpability or a failure to act, by or on behalf of any Indemnified Party. 
 8.4 Survival. The indemnification provided for under this Agreement will remain in full force and effect regardless of any investigation made by or on behalf of the Indemnified Party or any officer, director or
controlling Person of such Indemnified Party and will survive the transfer of securities. 
 9. Contribution. 
 9.1 Contribution. If the indemnification provided for in Section 8 from the Indemnifying Party is unavailable to or unenforceable by
the Indemnified Party in respect to any costs, fines, penalties, losses, claims, damages, liabilities or expenses referred to herein, then the Indemnifying Party, in lieu of indemnifying such Indemnified Party, shall contribute to the amount paid or
payable by such Indemnified Party as a result of such costs, fines, penalties, losses, claims, damages, liabilities or expenses in such proportion as is appropriate to reflect the relative fault of the Indemnifying Party and Indemnified Parties in
connection with the actions which resulted in such losses, claims, damages, liabilities or expenses, as well as any other relevant equitable considerations. The relative fault of such Indemnifying Party and Indemnified Parties shall be determined by
reference to, among other things, whether any action in question, including any untrue or alleged untrue statement of a material fact or omission or alleged omission to state a material fact, has been made by, or relates to information supplied by,
such Indemnifying Party or Indemnified Parties, and the parties’ relative intent, knowledge, access to 
  

 14 








 information and opportunity to correct or prevent such action. The amount paid or payable by a party as a result of the
costs, fines, penalties, losses, claims, damages, liabilities and expenses referred to above shall be deemed to include, subject to the limitations set forth in Section 8, any legal or other fees or expenses reasonably incurred by such
party in connection with any investigation or proceeding. For the avoidance of doubt and notwithstanding anything to the contrary contained herein, in no event shall any contribution by a holder of Registrable Securities under this
Section 9.1 exceed the gross proceeds received by such holder from the sale of Registrable Securities pursuant to such registration statement, except in the case of willful fraud. 
 9.2 Equitable Considerations; Etc. The Company and the holders of Registrable Securities agree that it would not be just and equitable if
contribution pursuant to this Section 9 were determined by pro rata allocation or by any other method of allocation which does not take into account the equitable considerations referred to in the immediately preceding paragraph. No
Person guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of the Securities Act) shall be entitled to contribution from any Person who was not guilty of such fraudulent misrepresentation. 
 10. Compliance with Rule 144 and Rule 144A. In the event that the Company (a) registers a class of securities under Section 12 of the
Exchange Act, (b) issues an offering circular meeting the requirements of Regulation A under the Securities Act or (c) commences to file reports under Section 13 or 15(d) of the Exchange Act, then at the request of any holder of
Registrable Securities who proposes to sell securities in compliance with Rule 144 of the Securities Act, the Company will (i) forthwith furnish to such holder a written statement of compliance with the filing requirements of the Commission as
set forth in Rule 144, as such rule may be amended from time to time and (ii) make available to the public and such holders such information, and take such action as is reasonably necessary, to enable the holders of Registrable Securities to
make sales pursuant to Rule 144. Unless the Company is subject to Section 13 or 15(d) of the Exchange Act, the Company will provide to the holder of Registrable Securities and to any prospective purchaser of Registrable Securities under Rule
144A of the Commission, the information described in Rule 144A(d)(4) of the Commission. 
 11. Participation in Underwritten
Registrations. No Person may participate in any registration hereunder which is underwritten unless such Person (a) agrees to sell its securities on the basis provided in any underwriting arrangements approved by such Person or Persons
entitled hereunder to approve such arrangements and (b) completes and executes all questionnaires, powers of attorney, custody agreements, indemnities, underwriting agreements and other documents reasonably required under the terms of such
underwriting arrangements. 
 12. Delay of Registration. No holder of Registrable Securities shall have any right to obtain or seek an
injunction restraining or otherwise delaying any registration as a result of any controversy that might arise with respect to the interpretation or implementation of this Agreement. 
 13. Assignment of Registration Rights. The rights to cause the Company to register Registrable Securities pursuant to this Agreement may be
assigned (but only with all related obligations) by a holder of Registrable Securities to a transferee or assignee (a) that is a subsidiary, parent, partner, limited partner, retired partner, member, retired member or 
  

 15 








 stockholder of a holder of Registrable Securities, (b) that is an affiliated fund or entity of the holder of
Registrable Securities, which means with respect to a limited liability company or a limited liability partnership, a fund or entity managed by the same manager or managing member or general partner or management company or by an entity controlling,
controlled by, or under common control with such manager or managing member or general partner or management company (such a fund or entity, an “Affiliated Fund”), (c) who is an Immediate Family Member of a holder of
Registrable Securities, or (d) that is a trust for the benefit of an individual holder of Registrable Securities or such holder’s Immediate Family Member, provided the Company is, within a reasonable time after such transfer,
furnished with a written notice of the name and address of such transferee or assignee and the securities with respect to which such registration rights are being assigned; and provided, further, that such assignment shall be effective only
if the transferee agrees to be bound by this Agreement and immediately following such transfer the further disposition of such securities by the transferee or assignee is restricted under the Securities Act. 
 14. Termination of Registration Rights. No holder of Registrable Securities shall be entitled to exercise any registration rights provided in this
Agreement after the earlier of (a) five (5) years following the consummation of a Qualified IPO or the Company becoming Public (as a result of the Merger or otherwise), or (b) such time as Rule 144 or another similar exemption under
the Securities Act is available for the sale of all of such holder’s shares of the Company’s equity securities during a three-month period without registration. 
 15. Miscellaneous. 
 15.1 Limitations on Subsequent Registration Rights. The Company has not
entered, and will not hereafter enter, into any agreement with respect to its securities which grants any superior or more favorable rights or terms to any Person than those provided to the holders of Registrable Securities in this Agreement.

 15.2 Adjustments Affecting Registrable Securities. The Company will not take any action, or permit any change to occur, with
respect to its Certificate of Incorporation, Bylaws, or other governing documents, as appropriate, which could reasonably be expected to adversely affect the ability of the holders of Registrable Securities to include such Registrable Securities in
a registration undertaken pursuant to this Agreement or which would reasonably be expected to adversely affect the marketability of such Registrable Securities in any such registration. 
 15.3 Amendments and Waivers. Except as otherwise expressly provided herein, the provisions of this Agreement may be amended or waived at any time
only by the written agreement of the Company and the holders of at least a majority of the Registrable Securities; provided, however, that the provisions of this Agreement may not be amended or waived without the consent of the holders of all
the Registrable Securities adversely affected by such amendment or waiver if such amendment or waiver adversely affects a portion of the Registrable Securities but does not so adversely affect all of the Registrable Securities. Any waiver, permit,
consent or approval of any kind or character on the part of any such holders of any provision or condition of this Agreement must be made in writing and shall be effective only to the extent specifically set forth in writing. Any amendment or waiver
effected in accordance with this paragraph shall be binding upon each holder of Registrable Securities and the Company. 
  

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 15.4 Successors and Assigns. Except as otherwise expressly provided herein, all covenants and
agreements contained in this Agreement by or on behalf of any of the parties hereto will bind and inure to the benefit of the respective successors and assigns of the parties hereto, whether so expressed or not. In addition, and whether or not any
express assignment has been made, the provisions of this Agreement which are for the benefit of holders of Registrable Securities are also for the benefit of, and enforceable by, any permitted transferee or assignee of such Registrable Securities as
provided for in Section 13 hereof and Section 7 of the Stockholders Agreement. 
 15.5 Descriptive Headings.
The descriptive headings of this Agreement are inserted for convenience of reference only and do not constitute a part of and shall not be utilized in interpreting this Agreement. 
 15.6 Notices. Any notices required or permitted to be sent hereunder shall be delivered personally, via facsimile transmission (with
confirmation), or mailed, via certified mail (return receipt requested), or delivered by overnight courier service to the following addresses, or such other address as any party hereto designates by written notice to the Company, and shall be deemed
to have been given upon delivery, if delivered personally or via facsimile, three (3) Business Days after mailing, if mailed, or one (1) Business Day after delivery to the courier, if delivered by overnight courier service: 
 if to the Company to: 
 VIA Pharmaceuticals, Inc. 
 750 Battery Street, Suite 330 
 San Francisco, California 94111 
 Attention: Chief Executive Officer 
 Telecopy: (415) 283-2201 
 with copies sent concurrently to: 
 Latham & Watkins LLP 
 5800 Sears Tower 
 233 South Wacker Drive 
 Chicago, Illinois 60606 
 Attention: Michael A. Pucker 
 Telecopy: (312) 993-9767 
 if to any holder of Registrable Securities: 
 to the address of such holder as the
same appears on 
 Exhibit A hereto (with copies to any parties 
 identified thereon) or, otherwise on the books and 
 records of the Company. 
  

 17 








 15.7 GOVERNING LAW. THIS AGREEMENT AND THE RIGHTS AND DUTIES OF THE PARTIES HERETO SHALL BE
GOVERNED BY THE LAWS OF THE STATE OF DELAWARE (WITHOUT REGARD TO CONFLICT OF LAWS PRINCIPLES). 
 15.8 Disputed Matters. Except as
otherwise provided in this Agreement, any controversy or dispute arising out of this Agreement, interpretation of any of the provisions hereof, or the action of any Stockholder hereunder shall be submitted to arbitration in San Francisco, California
before the American Arbitration Association under the commercial arbitration rules then obtaining of said Association. Any award or decision obtained from any such arbitration proceeding shall be final and binding on the parties, and judgment upon
any award thus obtained may be entered in any court having jurisdiction thereof. No action at law or in equity based upon any claim arising out of or related to this Agreement shall be instituted in any court by any Stockholder except (i) an
action to compel arbitration pursuant to this Section 15.8 or (ii) an action to enforce an award obtained in an arbitration proceeding in accordance with this Section 15.8, in which case, the provisions of Sections
15.9 and 15.10 shall apply. For the avoidance of doubt, the provisions of Sections 15.9 and 15.10 shall be subordinate to and shall only apply in connection with an action at law or in equity based upon clauses
(i) and/or (ii) of the immediately preceding sentence of this Section 15.8. 
 15.9 CONSENT TO
JURISDICTION. EACH PARTY HERETO HEREBY IRREVOCABLY AGREES THAT ANY SUIT, ACTION, PROCEEDING OR CLAIM AGAINST IT ARISING OUT OF OR IN ANY WAY RELATING TO THIS AGREEMENT OR ANY OF THE RELATED AGREEMENTS, OR ANY JUDGMENT ENTERED BY ANY COURT IN
RESPECT THEREOF, MAY BE BROUGHT OR ENFORCED IN THE STATE OR FEDERAL COURTS LOCATED IN SAN FRANCISCO, CALIFORNIA, AND EACH PARTY HERETO HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY LAW, ANY OBJECTION WHICH IT MAY NOW OR HEREAFTER
HAVE TO THE VENUE OF ANY PROCEEDING BROUGHT IN SAN FRANCISCO, CALIFORNIA AND FURTHER IRREVOCABLY WAIVES ANY CLAIMS THAT ANY SUCH PROCEEDING HAS BEEN BROUGHT IN AN INCONVENIENT FORUM. 
 15.10 WAIVER OF JURY TRIAL. EACH PARTY HERETO HEREBY EXPRESSLY WAIVES ANY RIGHT TO A TRIAL BY JURY IN ANY ACTION OR
PROCEEDING TO ENFORCE OR DEFEND ANY RIGHT, POWER, OR REMEDY UNDER OR IN CONNECTION WITH THIS AGREEMENT OR ANY OF THE RELATED AGREEMENTS OR UNDER OR IN CONNECTION WITH ANY AMENDMENT, INSTRUMENT, DOCUMENT, OR AGREEMENT DELIVERED OR WHICH MAY IN THE
FUTURE BE DELIVERED IN CONNECTION HEREWITH OR THEREWITH OR ARISING FROM ANY RELATIONSHIP EXISTING IN CONNECTION WITH THIS AGREEMENT OR ANY RELATED AGREEMENT, AND AGREE THAT ANY SUCH ACTION SHALL BE TRIED BEFORE A COURT AND NOT BEFORE A JURY. THE
TERMS AND PROVISIONS OF THIS SECTION CONSTITUTE A MATERIAL INDUCEMENT FOR THE PARTIES ENTERING INTO THIS AGREEMENT. 
  

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 15.11 Reproduction of Documents. This Agreement and all documents relating hereto, including, but
not limited to, (i) consents, waivers, amendments and modifications which may hereafter be executed, and (ii) certificates and other information previously or hereafter furnished, may be reproduced by any photographic, photostatic,
microfilm, optical disk, micro-card, miniature photographic or other similar process. The parties agree that any such reproduction shall be admissible in evidence as the original itself in any judicial or administrative proceeding, whether or not
the original is in existence and whether or not such reproduction was made by a party in the regular course of business, and that any enlargement, facsimile or further reproduction of such reproduction shall likewise be admissible in evidence.

 15.12 Remedies. Each of the parties to this Agreement will be entitled to enforce its rights under this Agreement specifically, to
recover damages by reason of any breach of any provision of this Agreement and to exercise all other rights existing in its favor. The parties hereto agree and acknowledge that money damages may not be an adequate remedy for any breach of the
provisions of this Agreement and that any party shall be entitled to immediate injunctive relief or specific performance without bond or the necessity of showing actual monetary damages in order to enforce or prevent any violations of the provisions
of this Agreement. 
 15.13 Severability. Whenever possible, each provision of this Agreement will be interpreted in such manner as to
be effective and valid under applicable law, but if any provision of this Agreement is held to be prohibited by or invalid under applicable law, such provision will be ineffective only to the extent of such prohibition or invalidity, without
invalidating the remainder of this Agreement. 
 15.14 Entire Agreement. This Agreement, together with all other agreements entered
into by the parties hereto in connection therewith, constitutes the complete and final agreement of the parties concerning the matters referred to herein, and supersedes all prior agreements and understandings, including, without limitation, the
Original Registration Rights Agreement. 
 15.15 Trustee Exculpation. For avoidance of doubt, when this Agreement is executed by a
trustee of a trust, such execution is by the trustee, not individually, but solely as trustee in the exercise of and under the power and authority conferred upon and invested in such trustee, and it is expressly understood and agreed that nothing
contained in this Agreement shall be construed as imposing any liability on any such trustee personally to pay any amounts required to be paid hereunder or thereunder, or to perform any covenant, either express or implied, contained herein or
therein, all such personal liability, if any, has been expressly waived by the parties by their execution hereof. Any liability of a trust shall not be a personal liability of any trustee, grantor or beneficiary thereof, and any recourse against a
trustee shall be solely against the assets of the pertinent trust. 
 15.16 Execution in Counterparts. This Agreement may be executed
in any number of counterparts, each of which when so executed and delivered shall be deemed an original, and such counterparts together shall constitute one instrument. 
 (Signature pages follow.) 
  

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 IN WITNESS WHEREOF, the parties hereto have executed this Registration Rights Agreement as of the date
first above written. 
  

			
	VIA PHARMACEUTICALS, INC.
		
	By:	 	  

	Name:	 	
	Title:	 	


 (Signature Page to Amended and Restated Registration Rights Agreement) 








					
	BAY CITY CAPITAL FUND IV, L.P.
		
	By:	 	Bay City Capital Management IV LLC
	Its:	 	General Partner
			
		 	By:	 	  

		 	Name:	 	
		 	Title:	 	
	
	BAY CITY CAPITAL FUND IV
	CO-INVESTMENT FUND, L.P.
		
	By:	 	Bay City Capital Management IV LLC
	Its:	 	General Partner
			
		 	By:	 	  

		 	Name:	 	
		 	Title:	 	


 (Signature Page to Amended and Restated Registration Rights Agreement) 








					
	 WS INVESTMENT COMPANY, LLC
 (2004A)

		
	By:	 	  

	Its:	 	  

			
		 	By:	 	  

		 	Name:	 	
		 	Title:	 	


 (Signature Page to Amended and Restated Registration Rights Agreement) 








					
	 WS INVESTMENT COMPANY, LLC
 (2004D)

		
	By:	 	  

	Its:	 	  

			
		 	By:	 	  

		 	Name:	 	
		 	Title:	 	


 (Signature Page to Amended and Restated Registration Rights Agreement) 








	
	  

	THOMAS QUERTERMOUS


 (Signature Page to Amended and Restated Registration Rights Agreement) 








	
	  

	ADEOYE OLUKOTUN


 (Signature Page to Amended and Restated Registration Rights Agreement) 








			
	 DOUGLASS AND KIM GIVEN
 REVOCABLE TRUST

		
	 By:
	 	  

		 	 Douglass Given, not individually, but solely
 in his
capacity as trustee of the trust



 (Signature Page to Amended and Restated Registration Rights Agreement) 








	
	  

	LAWRENCE COHEN


 (Signature Page to Amended and Restated Registration Rights Agreement) 








	
	  

	RAYMOND TABIBIAZAR


 (Signature Page to Amended and Restated Registration Rights Agreement) 







 EXHIBIT A 
 STOCKHOLDERS 
  

					
	 Name/Address:
	  	 No. of Shares of
 Common Stock
	  	 No. of Shares of
 Series A Preferred Stock

	 Bay City Capital Fund IV, L.P.
 750 Battery Street
 Suite 400
 San Francisco, CA 94111
	  	244,725	  	17,592,251
	 Bay City Capital Fund IV Co-Investment Fund, L.P.
 750 Battery Street
 Suite 400
 San Francisco, CA 94111
	  	5,275	  	379,200
	 WS Investment Company, LLC (2004A)
 650 Page Mill Road
 Palo Alto, CA 94304
	  	—  	  	20,134
	 WS Investment Company, LLC (2004D)
 650 Page Mill Road
 Palo Alto, CA 94304
	  	—  	  	20,134
	 Lawrence Cohen
 10065 Broadway Terrace
 Oakland, CA 94611
	  	247,625	  	74,285
	 Douglass and Kim Given Revocable Trust
 133 Burns Avenue
 Atherton, CA 94027
	  	250,000	  	80,536
	 Adeoye Olukotun
 125 Hopewell-Wertsville Road
 Hopewell, NJ 08525
	  	100,000	  	60,402
	 Thomas Quertermous
 810 Lathrop Drive
 Stanford, CA 94305
	  	217,292	  	—  
	 Raymond Tabibiazar
 750 Battery Street
 Suite 330
 San Francisco, CA 94111
	  	111,042	  	—