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# Isothermal aggregation kinetics of a low-pI mAb solution 

## Appears In

                        - Unfolding and Aggregation of Therapeutic Proteins

Figure 1. Isothermal aggregation kinetics of a low-pI mAb solution at 60 oC monitored by light scattering [1]. (inset) Schematic diagram depicting possible mechanisms of the effects of chaotropic ions such as magnesium (Mg2+) and thiocyanate (SCN–) on the physical stability of a slightly acidic mAb.

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