Exhibit
10.7


 


OMNIBUS
AMENDMENT TO 2014 TRANSACTION DOCUMENTS


 


This
Omnibus Amendment to Transaction Documents (this “Amendment”) dated as of August 3, 2015 (the “Effective
Date”), is entered into by and among (i) MELA Sciences, Inc., a Delaware corporation (the “Company”),
and (ii) the holders of the Company’s 4% Senior Secured Convertible Debentures due July 24, 2019 (the “Debentures”)
identified on the signature pages hereto (the “Purchasers” and each, a “Purchaser”).


 


1.           Purpose.
The Company and the Purchasers are parties to that certain Securities Purchase Agreement dated as of July 21, 2014 (the “Purchase
Agreement”) and the Transaction Documents (as defined in the Purchase Agreement). The Company has requested that the
Purchasers agree to the following amendments, waivers and consents, and the Purchasers agree to them on and subject to the terms
and conditions set forth herein and in reliance upon the representations and warranties of the Company set forth herein:


 


(a)          amendment
of the Purchase Agreement as set forth herein;


 


(b)          amendment
and restatement of the Security Agreement;


 


(c)          amendment
of the definition of Permitted Indebtedness in the Debentures to permit the 2015 Debt Securities (as defined below);


 


(d)          waiver,
by the Purchasers, of all pre-emptive rights, rights of first refusal and similar rights that the Purchasers have in connection
with the Company’s issuance, pursuant to that certain Securities Purchase Agreement dated as of June 22, 2015 (as amended,
the “2015 Purchase Agreement”) among the Company and the purchasers identified therein, of (i) the Company’s
2.25% Senior Secured Convertible Debentures due June 22, 2020 (the “2015 Series A Debentures”), (ii) the
Company’s 2.25% Series B Senior Unsecured Convertible Debentures due June 22, 2020 (the “2015 Series B Debentures”
and, together with the 2015 Series A Debentures, the “2015 Debentures”), (iii) the Company’s 9% Senior
Secured Notes (the “2015 Notes” and, together with the 2015 Debentures, the “2015 Debt Securities”),
with the original aggregate principal amount of the 2015 Debt Securities being $42,500,000, and (iv) the Company’s warrants
to purchase Common Stock issued in connection with the issuance of the 2015 Notes (the “2015 Warrants”); and


 


(e)          consent,
by the Purchasers, to the grant by the Company of liens over the Collateral (as defined in the Security Agreement) as security
for the Company’s obligations under the 2015 Series A Debentures and the 2015 Notes (collectively, the “2015 Secured
Debt Securities”).


 


All
capitalized terms used but not defined in this Amendment have the meanings given to them in the Purchase Agreement.


 


2.            Amendments
to Purchase Agreement. The Purchase Agreement is hereby amended as follows:


 


(a)          Schedule
3.1(aa) to the Purchase Agreement is amended and restated in its entirety as Schedule 3.1(aa) attached hereto.


 






    	 



    	 



    

 


(b)          Sections
4.12(c), (d) and (e) of the Purchase Agreement are hereby amended and restated in their entirety as follows:


 


(c)          any
Purchaser desiring to participate in such Subsequent Financing must provide written notice to the Company by not later than 5:30
p.m. (New York City time) on the second (2nd) Trading Day after all of the Purchasers have received the Subsequent Financing Notice
that such Purchaser is willing to participate in the Subsequent Financing, the amount of such Purchaser’s participation,
and representing and warranting that such Purchaser has such funds ready, willing, and available for investment on the terms set
forth in the Subsequent Financing Notice. If the Company receives no such notice from a Purchaser as of such second (2nd) Trading
Day, such Purchaser shall be deemed to have notified the Company that it does not elect to participate;


 


(d)          if
by 5:30 p.m. (New York City time) on the second (2nd) Trading Day after all of the Purchasers have received the Subsequent Financing
Notice, notifications by the Purchasers of their willingness to participate in the Subsequent Financing (or to cause their designees
to participate) is, in the aggregate, less than the Participation Maximum, then the Company may effect the remaining portion of
such Participation Maximum on the terms and with the Persons set forth in the Subsequent Financing Notice;


 


(e)          if
by 5:30 p.m. (New York City time) on the second (2nd) Trading Day after all of the Purchasers have received the Subsequent Financing
Notice, the Company receives responses to a Subsequent Financing Notice from Purchasers seeking to purchase more than the aggregate
amount of the Participation Maximum, each such Purchaser shall have the right to purchase its Pro Rata Portion (as defined below)
of the Participation Maximum. “Pro Rata Portion” means the ratio of (x) the Subscription Amount of Securities
purchased on the Closing Date by a Purchaser participating under this Section 4.12 and (y) the sum of the aggregate Subscription
Amounts of Securities purchased on the Closing Date by all Purchasers participating under this Section 4.12.


 






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(c)          Section
5.18 of the Purchase Agreement is hereby amended and restated in its entirety as follows:


 


5.18          Independent
Nature of Purchasers’ Obligations and Rights. The obligations of each Purchaser under the Transaction Documents are
several and not joint with the obligations of any other Purchaser, and no Purchaser shall be responsible in any way for the performance
or non-performance of the obligations of any other Purchaser under any Transaction Document. Nothing contained herein or in any
other Transaction Document, and no action taken by any Purchaser pursuant hereto or thereto, shall be deemed to constitute the
Purchasers as, and the Company acknowledges that the Purchasers do not so constitute, a partnership, an association, a joint venture
or any other kind of group or entity, or create a presumption that the Purchasers are in any way acting in concert or as a group
or entity with respect to such obligations or the transactions contemplated by the Transaction Documents or any matters, and the
Company acknowledges that the Purchasers are not acting in concert or as a group, and the Company shall not assert any such claim
with respect to such obligations or the transactions contemplated by the Transaction Documents. The decision of each Purchaser
to purchase Securities pursuant to the Transaction Documents has been made by such Purchaser independently of any other Purchaser.
Each Purchaser acknowledges that no other Purchaser has acted as agent for such Purchaser in connection with such Purchaser making
its investment hereunder and that no other Purchaser will be acting as agent of such Purchaser in connection with monitoring such
Purchaser’s investment in the Securities. The Company and each Purchaser confirms that each Purchaser has independently participated
with the Company and its Subsidiaries in the negotiation of the transaction contemplated hereby with the advice of its own counsel
and advisors. Each Purchaser shall be entitled to independently protect and enforce its rights, including, without limitation,
the rights arising out of this Agreement or out of any other Transaction Documents, and it shall not be necessary for any other
Purchaser to be joined as an additional party in any proceeding for such purpose. Each Purchaser has been represented by its own
separate legal counsel in its review and negotiation of the Transaction Documents. For reasons of administrative convenience only,
each Purchaser and its respective counsel have chosen to communicate with the Company through GP. GP does not represent the Purchasers
other than Broadfin. EGS does not represent the Purchasers other than Sabby. The Company has elected to provide all Purchasers
with the same terms and Transaction Documents for the convenience of the Company and not because it was required or requested
to do so by any of the Purchasers. The use of a single agreement to effectuate the purchase and sale of the Securities contemplated
hereby was solely in the control of the Company, not the action or decision of any Purchaser, and was done solely for the convenience
of the Company and its Subsidiaries and not because it was required or requested to do so by any Purchaser. It is expressly understood
and agreed that each provision contained in this Agreement and in each other Transaction Document is between the Company, each
Subsidiary and a Purchaser, solely, and not between the Company, its Subsidiaries and the Purchasers collectively and not between
and among the Purchasers.


 


3.           Amendment
to Security Agreement.  The Security Agreement is hereby amended by amending and restating the Security Agreement in
its entirety in the form attached hereto as Exhibit A.


 


4.           Amendment
to Debentures. Each of the Debentures is hereby amended by replacing the definition of “Permitted Indebtedness”
in Section 1 therein in its entirety as follows:


 


“Permitted
Indebtedness” means (a) the indebtedness evidenced by the Debentures, (b) the Indebtedness set forth on Schedule
3.1(aa) attached to the Purchase Agreement, (c) lease obligations and purchase money indebtedness of up to $150,000, in the
aggregate per year, incurred in connection with the acquisition of capital assets and lease obligations with respect to newly
acquired or leased assets, and (d) other indebtedness incurred in the ordinary course of business up to $250,000 at any time outstanding.


 






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5.           Waiver
and Consent by Purchasers. Each of the Purchasers hereby irrevocably and unconditionally (i) waives any and all rights
it may have pursuant to the Purchase Agreement, including but not limited to Section 4.12 therein, which conflict with the
consummation of the transactions contemplated by the 2015 Purchase Agreement and the agreements executed in connection therewith,
including the issuance of the 2015 Debt Securities and the 2015 Warrants, and (ii) consents to the issuance by the Company
of the 2015 Debt Securities and the 2015 Warrants and the grant by the Company of liens over the Collateral as security for
the Company’s obligations under the 2015 Secured Debt Securities.


 


6.           Representations
and Warranties.


 


(a)          The
Company represents and warrants to the Purchasers that (i) the Purchasers are the only holders of Debentures registered on
the Debenture Register as of the date hereof, (ii) according to the Company’s share register, as of the date hereof the
Purchasers hold a majority in interest of the Securities, (iii) after giving effect to this Amendment, no Event of Default exists;
(iv) the Company has performed and complied with all covenants, agreements, obligations and conditions contained in the Purchase
Agreement and the Transaction Documents that are required to be performed or complied with by it; and (v) no injunction or restraining
order is in effect prohibiting the transactions contemplated hereby. The Company acknowledges, confirms and agrees that, as of
the date hereof, the Company has no knowledge of any offsets, defenses, claims or counterclaims against any Purchaser with respect
to any of the Company’s liabilities and obligations to the Purchasers under the Transaction Documents.


 


(b)          Each
of the Purchasers represents and warrants to the Company that such Purchaser, without having conducted any investigation, does
not know of any injunction or restraining order in effect prohibiting such Purchaser from consummating the transactions contemplated
hereby.


 


7.           Effectiveness.
This Amendment will become effective upon receipt by the Agent of (a) counterparts of this Amendment executed by the Company and
each Purchaser, (b) the effectiveness, according to its terms, of that certain Omnibus Amendment to 2015 Transaction Documents
dated on or about the date hereof among the Company and the purchasers identified therein, and (c) reimbursement for all expenses
incurred in connection with this Amendment (including all reasonable attorney’s fees and expenses) and invoiced to the Company.


 






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8.           Miscellaneous.
Except as expressly amended herein, all of the terms and conditions of the Transaction Documents remain unchanged and in full
force and effect, and each Transaction Document (as modified herein) is hereby ratified and confirmed. This Amendment may be executed
in counterparts, each of which shall constitute an original but all of which shall together constitute one and the same Amendment.
The execution of this Amendment and acceptance of any documents related hereto shall not be deemed to be a waiver of any breach,
or Event of Default under the Transaction Documents, whether or not known to Agent or any Purchaser and whether or not existing
on the date of this Amendment. Any determination that any provision of this Amendment or any application hereof is invalid, illegal
or unenforceable in any respect and in any instance shall not affect the validity, legality, or enforceability of such provision
in any other instance, or the validity, legality or enforceability of any other provisions of this Amendment. All rights and obligations
hereunder, including matters of construction, validity, and performance, shall be governed by and construed in accordance with
the law of the State of New York, without regard to the conflicts of law provisions of the State of New York or of any other state.


 


[Signature
Page Follows]


 






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IN
WITNESS WHEREOF, the parties have caused this Omnibus Amendment to 2014 Transaction Documents to be duly executed and delivered
by their proper and duly authorized representatives as of the date and year first written above.


 





	 	COMPANY:
	 	 
	 	MELA SCIENCES, INC.
	 	 
	 	By: 	
	 	 	Michael
                                         R. Stewart


Chief
Executive Officer








 


[SIGNATURE
PAGES OF PURCHASERS FOLLOW]


 






    	[Signature page to Omnibus Amendment TO
2014 Transaction Documents]








    	 



    

 


[SIGNATURE
PAGE OF PURCHASER TO OMNIBUS AMENDMENT

TO 2014 TRANSACTION DOCUMENTS] 





	 	 
	Name of Investing Entity: 	 






	 	 
	Signature of Authorized Signatory of Investing Entity:  	 






	 	 
	Name of Authorized Signatory:  	 






	 	 
	Title of Authorized Signatory:  	 



 






    	 



    	 



    

   


Schedule
3.1(aa)


 


Indebtedness


 


the
2015 Debt Securities


 






    	 



    	 



    

 


Exhibit
A


 


Amended
and Restated Security Agreement


 






    	 



    	 



    

 


AMENDED
AND RESTATED

SECURITY AGREEMENT


 


This
AMENDED AND RESTATED SECURITY AGREEMENT, dated as of  August 3, 2015 (this “Agreement”), is among
MELA Sciences, Inc., a Delaware corporation (the “Company”), any Additional Debtors (as such term is defined
herein and, together with the Company, the “Debtors”), and the holders (collectively, the “Secured
Parties”) of the Company’s 4% Senior Secured Convertible Debentures due July 24, 2019, in the original aggregate
principal amount of $15,000,000 (collectively, the “Debentures”).


 


W
I T N E S S E T H:


 


WHEREAS,
pursuant to the Purchase Agreement (as defined in the Debentures), the Secured Parties have severally extended to the Company
the loans evidenced by the Debentures; and


 


WHEREAS,
the Debtors as of the date hereof are parties to that certain Security Agreement dated as of July 21, 2014 (the “Existing
Security Agreement”) entered into pursuant to the Purchase Agreement;


 


NOW,
THEREFORE, in consideration of the agreements herein contained and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto, having the consent of the requisite Purchasers (as such term
is defined in the Purchase Agreement), hereby agree to amend and restate in its entirety the Existing Security Agreement as follows:


 


1.           Certain
Definitions. As used in this Agreement, the following terms shall have the meanings set forth in this Section 1. Terms used
but not otherwise defined in this Agreement that are defined in Article 9 of the UCC (such as “account”, “chattel
paper”, “commercial tort claim”, “deposit account”, “document”, “equipment”,
“fixtures”, “general intangibles”, “goods”, “instruments”, “inventory”,
“investment property”, “letter-of-credit rights”, “proceeds” and “supporting obligations”)
shall have the respective meanings given such terms in Article 9 of the UCC.


 







    	 



    	 



    

 

(a)          “Collateral”
means the collateral in which the Secured Parties are granted a security interest by this Agreement and includes the following
personal property of the Debtors, whether presently owned or existing or hereafter acquired or coming into existence, wherever
situated, and all additions and accessions thereto and all substitutions and replacements thereof, and all proceeds, products
and accounts thereof, including, without limitation, all proceeds from the sale or transfer of the Collateral and of insurance
covering the same and of any tort claims in connection therewith, and all dividends, interest, cash, notes, securities, equity
interest or other property at any time and from time to time acquired, receivable or otherwise distributed in respect of, or in
exchange for, any or all of the Pledged Securities (as defined below):


 


(i)          All
goods, including, without limitation, (A) all machinery, equipment, computers, motor vehicles, trucks, tanks, boats, ships, appliances,
furniture, special and general tools, fixtures, test and quality control devices and other equipment of every kind and nature
and wherever situated, together with all documents of title and documents representing the same, all additions and accessions
thereto, replacements therefor, all parts therefor, and all substitutes for any of the foregoing and all other items used and
useful in connection with any Debtor’s businesses and all improvements thereto; and (B) all inventory;


 


(ii)         All
contract rights and other general intangibles, including, without limitation, all partnership interests, membership interests,
stock or other securities, other than Excluded Property, rights under any of the Organizational Documents, agreements related
to the Pledged Securities, licenses, distribution and other agreements, computer software (whether “off-the-shelf”,
licensed from any third party or developed by any Debtor), computer software development rights, leases, franchises, customer
lists, quality control procedures, grants and rights, goodwill, Intellectual Property and income tax refunds;


 


(iii)        All
accounts, together with all instruments, all documents of title representing any of the foregoing, all rights in any merchandising,
goods, equipment, motor vehicles and trucks which any of the same may represent, and all right, title, security and guaranties
with respect to each account, including any right of stoppage in transit;


 


(iv)        All
documents, letter-of-credit rights, instruments and chattel paper;


 


(v)         All
commercial tort claims;


 


(vi)        All
deposit accounts and all cash (whether or not deposited in such deposit accounts);


 


(vii)       All
investment property and all ownership and/or other equity interests in each Subsidiary, including, without limitation, the Subsidiary
Equity Interests, and, in each case, all certificates representing such shares and/or equity interests and, in each case, all
rights, options, warrants, stock, other securities and/or equity interests that may hereafter be received, receivable or distributed
in respect of, or exchanged for, any of the foregoing and all rights arising thereunder or in connection therewith, including,
but not limited to, all dividends, interest and cash, other than Excluded Property (collectively, the “Pledged Securities”);


 


(viii)      All
supporting obligations; and


 


(ix)        All
files, records, books of account, business papers, and computer programs; and


 


(x)          the
products and proceeds of all of the foregoing.


 






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Notwithstanding
the foregoing, (A) nothing herein shall be deemed to constitute the grant of a security interest in, or an assignment of,
any asset (i) in which a security interest or assignment is void by operation of applicable law, or is otherwise prohibited by
applicable law (in each case to the extent that such applicable law is not overridden by Sections 9-406, 9-407 and/or 9-408 of
the UCC or other similar applicable law), or (ii) subject to any governmental permit, approval or license not related to Intellectual
Property, if and to the extent that a security interest therein, or assignment thereof, is prohibited by or in violation of (x)
any applicable law, or (y) a term, provision or condition of any such governmental permit, approval or license (unless in each
case, such applicable law, term, provision or condition would be rendered ineffective with respect to the creation of such security
interest pursuant to Sections 9-406, 9-407, 9-408 or 9-409 of the UCC); provided, however, that to the extent permitted
by applicable law, this Agreement shall create a valid security interest in such asset and, to the extent permitted by applicable
law, this Agreement shall create a valid security interest in the proceeds of such asset and (B) the Collateral does not
include any Excluded Property.


 


(b)          “Commencement
Notice” means a written notice, given by any Secured Party to the other Secured Parties in accordance with the notice
provisions set forth in the Purchase Agreement, pursuant to which such Secured Party notifies the other Secured Parties (i) of
the existence of one or more Events of Default, including a reasonably detailed description of each such Event of Default, and
(ii) of such Secured Party’s intent to commence the exercise of one or more of the remedies provided for under this Agreement
with respect to all or any portion of the Collateral as a consequence thereof, including a reasonably detailed description of
the remedial action such Secured Party proposes to take.


 


(c)          “Event
of Default” has the meaning ascribed to such term in the Debentures.


 


(d)          “Excluded
Property” means 35% of the equity interests in any Subsidiary organized in a jurisdiction outside of the United States.


 


(e)          “Intellectual
Property” means the collective reference to all rights, priorities and privileges relating to intellectual property,
whether arising under United States, multinational or foreign laws or otherwise, including, without limitation, (i) all copyrights
arising under the laws of the United States, any other country or any political subdivision thereof, whether registered or unregistered
and whether published or unpublished, all registrations and recordings thereof, and all applications in connection therewith,
including, without limitation, all registrations, recordings and applications in the United States Copyright Office, (ii) all
letters patent of the United States, any other country or any political subdivision thereof, all reissues and extensions thereof,
and all applications for letters patent of the United States or any other country and all divisions, continuations and continuations-in-part
thereof, (iii) all trademarks, trade names, corporate names, company names, business names, fictitious business names, trade dress,
service marks, logos, domain names and other source or business identifiers, and all goodwill associated therewith, now existing
or hereafter adopted or acquired, all registrations and recordings thereof, and all applications in connection therewith, whether
in the United States Patent and Trademark Office or in any similar office or agency of the United States, any State thereof or
any other country or any political subdivision thereof, or otherwise, and all common law rights related thereto, (iv) all trade
secrets arising under the laws of the United States, any other country or any political subdivision thereof, (v) all rights to
obtain any reissues, renewals or extensions of the foregoing, (vi) all licenses for any of the foregoing, and (vii) all causes
of action for infringement of the foregoing.


 






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(f)          “Liens”
has the meaning ascribed to such term in the Purchase Agreement.


 


(g)          “Majority
in Interest” means, at any time of determination, the majority in interest (based on then-outstanding principal amounts
of Debentures at the time of such determination) of the Secured Parties.


 


(h)          “Necessary
Endorsement” means undated stock powers endorsed in blank or other proper instruments of assignment duly executed and
such other instruments or documents as the Agent may reasonably request.


 


(i)          “Obligations”
means all of the liabilities and obligations (primary, secondary, direct, contingent, sole, joint or several) due or to become
due, or that are now or may be hereafter contracted or acquired, or owing to, of any Debtor to the Secured Parties, under this
Agreement, the Debentures, the Subsidiary Guarantee (to be entered into pursuant to the terms of the Purchase Agreement by any
Additional Debtors) (the “Guarantee”), the other Transaction Documents and any other instruments, agreements
or other documents executed and/or delivered in connection herewith or therewith, in each case, whether now or hereafter existing,
voluntary or involuntary, direct or indirect, absolute or contingent, liquidated or unliquidated, whether or not jointly owed
with others, and whether or not from time to time decreased or extinguished and later increased, created or incurred, and all
or any portion of such obligations or liabilities that are paid, to the extent all or any part of such payment is avoided or recovered
directly or indirectly from any of the Secured Parties as a preference, fraudulent transfer or otherwise as such obligations may
be amended, supplemented, converted, extended or modified from time to time. Without limiting the generality of the foregoing,
the term “Obligations” shall include, without limitation: (i) principal of, and interest on the Debentures and the
loans extended pursuant thereto; (ii) any and all other fees, indemnities, costs, obligations and liabilities of the Debtors from
time to time under or in connection with this Agreement, the Debentures, the Guarantee, the other Transaction Documents and any
other instruments, agreements or other documents executed and/or delivered in connection herewith or therewith; and (iii) all
amounts (including but not limited to post-petition interest) in respect of the foregoing that would be payable but for the fact
that the obligations to pay such amounts are unenforceable or not allowable due to the existence of a bankruptcy, reorganization
or similar proceeding involving any Debtor.


 


(j)          “Organizational
Documents” means with respect to any Debtor, the documents by which such Debtor was organized (such as a certificate
of incorporation, certificate of limited partnership or articles of organization, and including, without limitation, any certificates
of designation for preferred stock or other forms of preferred equity) and which relate to the internal governance of such Debtor
(such as bylaws, a partnership agreement or an operating, limited liability or members agreement).


 






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(k)          “Permitted
Liens” has the meaning ascribed to such term in the Debentures.


 


(l)          “Permitted
Secured Party” means, with respect to the exercise of any remedy provided for under this Agreement, any Secured Party
that has delivered a Commencement Notice with respect to the exercise of such remedy to the other Secured Parties and has not
received a Veto Notice with respect thereto within the Veto Period (other than a Commencement Notice as to which the Veto Period
does not apply); provided, however, there shall only be a single Permitted Secured Party that may exercise any specific
remedy at any one time (it being agreed that if a Commencement Notice is delivered by more than one Secured Party with respect
to any remedy provided for under this Agreement, then the first Secured Party to deliver a Commencement Notice and not receive
a Veto Notice within the Veto Period shall be the only Secured Party that may exercise such remedy).


 


(m)          “Pledged
Interests” has the meaning ascribed to such term in Section 4(j).


 


(n)          “Pledged
Securities” has the meaning ascribed to such term in Section 1(a).


 


(o)          “Significant
Secured Party” means, on any date of determination, any Secured Party holding twenty-five percent (25%) or more of the
aggregate principal amount of Debentures outstanding on such date.


 


(p)          “Veto
Notice” means, with respect to any Commencement Notice (other than a Commencement Notice as to which the Veto Period
does not apply), a written notice given by any Significant Secured Party to the other Secured Parties in accordance with the notice
provisions set forth in the Purchase Agreement pursuant to which such Significant Secured Party notifies the other Secured Parties
of its objection to the commencement of the remedial action specified in such Commencement Notice and certifies that, to the best
of its knowledge, it is a Significant Secured Party.


 


(q)          “Veto
Period” means, with respect to any Commencement Notice (other than a Commencement Notice given by a Significant Secured
Party at a time when such Significant Secured Party is the only the Significant Secured Party), the period of ten (10) consecutive
calendar days following the delivery of such Commencement Notice to the Secured Parties.


 


(r)          “UCC”
means the Uniform Commercial Code of the State of New York and or any other applicable law of any state or states which has jurisdiction
with respect to all, or any portion of, the Collateral or this Agreement, from time to time.


 






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2.           Grant
of Security Interest in Collateral. As an inducement for the Secured Parties to extend the loans evidenced by the Debentures
and to secure the complete and timely payment, performance and discharge in full, as the case may be, of all of the Obligations,
each Debtor hereby unconditionally and irrevocably pledges, grants and hypothecates to the Secured Parties a security interest
in and to, a lien upon and a right of set-off against all of their respective right, title and interest of whatsoever kind and
nature in and to, the Collateral (a “Security Interest” and, collectively, the “Security Interests”).


 


3.           Delivery
of Certain Collateral. Contemporaneously or prior to the execution of this Agreement, each Debtor shall deliver or cause to
be delivered to the Agent any and all certificates and other instruments or documents representing any of the Collateral, together
with all Necessary Endorsements. If and when the Collateral includes Pledged Securities, each Debtor shall deliver or cause to
be delivered to the Agent any and all certificates and other instruments representing or evidencing such Pledged Securities, together
with all Necessary Endorsements and each Organizational Document governing such Pledged Securities.


 


4.           Representations,
Warranties, Covenants and Agreements of the Debtors. Except as set forth under the corresponding section of the disclosure
schedules delivered to the Secured Parties concurrently herewith (the “Disclosure Schedules”), which Disclosure
Schedules shall be deemed a part hereof, each Debtor represents and warrants to, and covenants and agrees with, the Secured Parties
as follows:


 


(a)          Each
Debtor has the requisite corporate, partnership, limited liability company or other entity power and authority to enter into this
Agreement and otherwise to carry out its obligations hereunder. The execution, delivery and performance by each Debtor of this
Agreement and the filings contemplated herein have been duly authorized by all necessary action on the part of such Debtor and
no further action is required by such Debtor. This Agreement has been duly executed by each Debtor. This Agreement constitutes
the legal, valid and binding obligation of each Debtor, enforceable against each Debtor in accordance with its terms except as
such enforceability may be limited by applicable bankruptcy, insolvency, reorganization and similar laws of general application
relating to or affecting the rights and remedies of creditors and by general principles of equity.


 


(b)          The
Debtors have no place of business or offices where their respective books of account and records are kept (other than temporarily
at the offices of its attorneys or accountants) or places where Collateral is stored or located, except as set forth on Schedule
4.(b) attached hereto. Except as disclosed on Schedule 4.(b), (i) no Debtor owns any real property and (ii) none of
the Collateral is in the possession of any consignee, bailee, warehouseman, agent or processor.


 


(c)          Except
for Permitted Liens, each of the Debtors is the sole owner of the Collateral it purports to own (except for non-exclusive licenses
granted by any Debtor in the ordinary course of business), free and clear of any Liens and is fully authorized to grant the Security
Interests. Except as set forth on Schedule 4.(c) attached hereto, there is not on file in any governmental or regulatory
authority, agency or recording office an effective financing statement, security agreement, license or transfer or any notice
of any of the foregoing (other than those that will be filed in favor of the Secured Parties pursuant to this Agreement) covering
or affecting any of the Collateral. Except as set forth on Schedule 4.(c) attached hereto and except pursuant to this Agreement,
as long as this Agreement shall be in effect, the Debtors shall not execute and shall not knowingly permit to be on file in any
such office or agency any other financing statement or other document or instrument (except to the extent filed or recorded in
favor of the Secured Parties pursuant to the terms of this Agreement).


 






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(d)          No
written claim has been received that any material portion of Collateral or any Debtor’s use of any material portion of Collateral
violates the rights of any third party. There has been no adverse decision to any Debtor’s claim of ownership rights in
or exclusive rights to use the Collateral in any jurisdiction or to any Debtor’s right to keep and maintain such Collateral
in full force and effect, and there is no legal proceeding involving said rights pending or, to the best knowledge of any Debtor,
threatened in writing before any court, judicial body, administrative or regulatory agency, arbitrator or other governmental authority.


 


(e)          Each
Debtor shall at all times maintain its books of account and records relating to the Collateral at its principal place of business
and its Collateral at the locations set forth on Schedule 4.(b) attached hereto and may not relocate such books of account
and records or tangible Collateral unless it delivers to the Secured Parties at least 10 days prior to such relocation (i) written
notice of such relocation and the new location thereof (which must be within the United States) and (ii) evidence that appropriate
financing statements under the UCC and other necessary documents have been filed and recorded and other steps have been taken
to perfect the Security Interests to create in favor of the Secured Parties a valid, perfected and continuing perfected first
priority lien in the Collateral, subject to Permitted Liens.


 


(f)          This
Agreement creates in favor of the Secured Parties a valid security interest in the Collateral located in the United States, subject
only to Permitted Liens, securing the payment and performance of the Obligations. Upon making the filings described in this Agreement,
all security interests created hereunder in any Collateral located in the United States which may be perfected by filing Uniform
Commercial Code financing statements will have been duly perfected. Except for the filing of the Uniform Commercial Code financing
statements referred to in the immediately following paragraph, the recordation of the Intellectual Property Security Agreement
(as defined in Section 4(p) hereof) with respect to copyrights and copyright applications in the United States Copyright
Office referred to in paragraph (m), the execution and delivery of deposit account control agreements satisfying the requirements
of Section 9-104(a)(2) of the UCC with respect to each deposit account of the Debtors, and the delivery of the certificates and
other instruments provided in Section 3, no action is necessary to create, perfect or protect the security interests created hereunder
in Collateral located in the United States. Without limiting the generality of the foregoing, except for the filing of said financing
statements, the recordation of said Intellectual Property Security Agreement and the execution and delivery of said deposit account
control agreements, no consent of any third parties and no authorization, approval or other action by, and no notice to or filing
with, any governmental authority or regulatory body is required for (i) the execution, delivery and performance of this Agreement,
(ii) the creation or perfection of the Security Interests created hereunder in the Collateral located in the United States or
(iii) the enforcement of the rights of the Agent and the Secured Parties hereunder, other than consents from holders of Permitted
Liens obtained in writing and delivered to the Secured Parties prior to the date of this Agreement.


 






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(g)          Each
Debtor hereby authorizes each of the Secured Parties to file one or more financing statements under the UCC, with respect to the
Security Interests, with the proper filing and recording agencies in any jurisdiction deemed proper by it.


 


(h)          The
execution, delivery and performance of this Agreement by the Debtors does not (i) violate any of the provisions of any Organizational
Documents of any Debtor or any judgment, decree, order or award of any court, governmental body or arbitrator or any applicable
law, rule or regulation applicable to any Debtor or (ii) conflict with, or constitute a default (or an event that with notice
or lapse of time or both would become a default) under, or give to others any rights of termination, amendment, acceleration or
cancellation (with or without notice, lapse of time or both) of, any material agreement, or credit facility, to which any Debtor
is a party or by which any property or asset of any Debtor is bound or affected. If any, all required consents (including, without
limitation, from stockholders or creditors of any Debtor) necessary for any Debtor to enter into and perform its obligations hereunder
have been obtained.


 


(i)          The
capital stock and other equity interests listed on Schedule 4.(i) hereto (the “Subsidiary Equity Interests”)
represent all of the capital stock and other equity interests of the Subsidiaries, and represent all capital stock and other equity
interests owned, directly or indirectly, by the Debtors. All of the Subsidiary Equity Interests are validly issued, fully paid
and nonassessable. Each Debtor that is indicated on Schedule 4.(i) to be the owner of Subsidiary Equity Interests is the
legal and beneficial owner of such Subsidiary Equity Interests, free and clear of any lien, security interest or other encumbrance
except for the security interests created by this Agreement and other Permitted Liens.


 


(j)          The
ownership and other equity interests in partnerships and limited liability companies (if any) included in the Collateral (the
“Pledged Interests”) by their express terms do not provide that they are securities governed by Article 8 of
the UCC and are not held in a securities account or by any financial intermediary.


 


(k)          Except
for Permitted Liens, each Debtor shall at all times maintain the liens and Security Interests provided for hereunder as valid
and perfected first priority liens and security interests in the Collateral located in the United States in favor of the Secured
Parties until this Agreement and the Security Interest hereunder shall be terminated pursuant to Section 14 hereof. Each Debtor
hereby agrees to defend the same against the claims of any and all persons and entities. Each Debtor shall safeguard and protect
all Collateral for the account of the Secured Parties. At the request of any of the Secured Parties, each Debtor will authorize
each of the Secured Parties at any time or from time to time as reasonably necessary one or more financing statements pursuant
to the UCC in form reasonably satisfactory to the Secured Parties and will pay the cost of filing the same in all public offices
wherever filing is, or is deemed by the Secured Parties to be, necessary to effect the rights and obligations provided for herein.
Without limiting the generality of the foregoing, each Debtor shall pay all fees, taxes and other amounts necessary to maintain
the Collateral and the Security Interests hereunder, and each Debtor shall obtain and furnish to the Agent from time to time,
upon reasonable request, such releases and/or subordinations of claims and liens which may be required to maintain the priority
of the Security Interests hereunder.


 






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(l)          No
Debtor will transfer, pledge, hypothecate, encumber, license, sell or otherwise dispose of any of the Collateral (except for non-exclusive
licenses granted by a Debtor in its ordinary course of business, sales of inventory by a Debtor in its ordinary course of business
and other Collateral which is no longer useful or material to a Debtor’s business) without the prior written consent of
a Majority in Interest.


 


(m)          Each
Debtor shall keep and preserve its equipment, inventory and other tangible Collateral in good condition, repair and order, subject
to ordinary wear and tear, and shall not operate or locate any such Collateral (or cause to be operated or located) in any area
excluded from insurance coverage.


 


(n)          Each
Debtor shall maintain with financially sound and reputable insurers, insurance with respect to the Collateral, including Collateral
hereafter acquired, against loss or damage of the kinds and in the amounts customarily insured against by entities of established
reputation having similar properties similarly situated and in such amounts as are customarily carried under similar circumstances
by other such entities and otherwise as is prudent for entities engaged in similar businesses but in any event sufficient to cover
the full replacement cost thereof. Each Debtor shall cause each insurance policy issued in connection herewith to provide, and
the insurer issuing such policy to certify to the Secured Parties, that (a) the Secured Parties will be named as lender loss payees
and additional insureds under each such insurance policy; (b) if such insurance be proposed to be cancelled or materially changed
for any reason whatsoever, such insurer will promptly notify the Secured Parties and such cancellation or material change shall
not be effective as to the Secured Parties for at least thirty (30) days after receipt by the Secured Parties of such notice,
unless the effect of such change is to extend or increase coverage under the policy; and (c) the Secured Parties will have the
right (but no obligation) at its election to remedy any default in the payment of premiums within thirty (30) days of notice from
the insurer of such default. If no Event of Default exists and if the aggregate insurance policy proceeds arising out of any claim
or series of related claims do not exceed $100,000, loss payments in each instance will be applied by the Debtors to the repair
and/or replacement of property with respect to which the loss was incurred to the extent reasonably feasible, and any loss payments
or the balance thereof remaining, to the extent not so applied, shall be payable to the Debtors; provided, however,
that payments received by the Debtors after an Event of Default occurs and is continuing or in excess of $100,000 for any occurrence
or series of related occurrences shall be paid to the Secured Parties and, if received by the Debtors, shall be held in trust
for the Secured Parties and immediately paid over to the Secured Parties unless otherwise directed in writing by the Secured Parties.
Copies of such policies or the related certificates, in each case, naming the Secured Parties as lender loss payee and additional
insured shall be delivered to the Secured Parties at least annually and at the time any new policy of insurance is issued.


 






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(o)          Each
Debtor shall, within ten (10) days of obtaining knowledge thereof, advise the Secured Parties promptly, in sufficient detail,
of any material adverse change in the Collateral as a whole, and of the occurrence of any event which would have a material adverse
effect on the value of the Collateral as a whole or on the Secured Parties’ security interest therein.


 


(p)          Each
Debtor shall promptly execute and deliver to the Secured Parties such further deeds, mortgages, assignments, security agreements,
financing statements or other instruments, documents, certificates and assurances and take such further action as any Secured
Party may from time to time reasonably request to perfect, protect or enforce the Secured Parties’ security interest in
the Collateral including, without limitation, if applicable, the execution and delivery of a separate security agreement with
respect to each Debtor’s Intellectual Property (“Intellectual Property Security Agreement”) in which
the Secured Parties have been granted a security interest hereunder, substantially in a form reasonably acceptable to the Secured
Parties, which Intellectual Property Security Agreement, other than as stated therein, shall be subject to all of the terms and
conditions hereof.


 


(q)          Each
Debtor shall permit the Secured Parties and their respective representatives and agents to inspect the Collateral during normal
business hours and upon at least two (2) Business Day’s prior notice, and to make copies of records pertaining to the Collateral
as may be reasonably requested by the Secured Parties from time to time.


 


(r)          Each
Debtor shall take all steps reasonably necessary to diligently pursue and seek to preserve, enforce and collect any rights, claims,
causes of action and accounts receivable in respect of the Collateral.


 


(s)          Each
Debtor shall promptly notify the Secured Parties in sufficient detail upon becoming aware of any attachment, garnishment, execution
or other legal process levied against any Collateral and of any other information received by such Debtor that may reasonably
be expected to materially and adversely affect the value of the Collateral as a whole, the Security Interest or the rights and
remedies of the Secured Parties hereunder.


 


(t)          All
information heretofore, herein or hereafter supplied to the Agent or the Secured Parties by or on behalf of any Debtor with respect
to the Collateral is accurate and complete in all material respects as of the date furnished.


 


(u)          The
Debtors shall at all times preserve and keep in full force and effect their respective valid existence and good standing and any
rights and franchises material to its business.


 


(v)          No
Debtor will change its name, type of organization, jurisdiction of organization, organizational identification number (if it has
one), legal or corporate structure, or identity, unless it provides at least 10 days prior written notice to the Secured Parties
of such change and, at the time of such written notification, such Debtor provides any financing statements or fixture filing
necessary to perfect and continue the perfection of the Security Interests granted and evidenced by this Agreement.


 






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(w)          Except
in the ordinary course of business, no Debtor will consign any of its inventory or sell any of its inventory on bill and hold,
sale or return, sale on approval, or other conditional terms of sale without the consent of the Secured Parties, which consent
shall not be unreasonably withheld.


 


(x)          No
Debtor will relocate its chief executive office to a new location without (i) providing 30 days prior written notification thereof
to the Secured Parties and (ii) providing any financing statements or fixture filings necessary to perfect and continue the perfection
of the Security Interests granted and evidenced by this Agreement.


 


(y)          Each
Debtor was organized and remains organized solely under the laws of the state set forth next to such Debtor’s name in Schedule
4.(y) attached hereto, which Schedule 4.(y) sets forth each Debtor’s organizational identification number or,
if any Debtor does not have one, states that one does not exist.


 


(z)          (i)
The actual name of each Debtor is the name set forth in Schedule 4.(y) attached hereto; (ii) no Debtor has any trade names
except as set forth on Schedule 4.(z) attached hereto; (iii) no Debtor has used any name other than that stated in the
preamble hereto or as set forth on Schedule 4.(z) for the preceding five years; and (iv) no entity has merged into any
Debtor or been acquired by any Debtor within the past five years except as set forth on Schedule 4.(z).


 


(aa)          At
any time and from time to time that any Collateral consists of instruments, certificated securities or other items that require
or permit possession by the secured party to perfect the security interest created hereby, the applicable Debtor shall deliver
such Collateral to the Agent.


 


(bb)          Each
Debtor, in its capacity as issuer, shall comply with any and all orders and instructions of the Secured Parties regarding the
Pledged Interests consistent with the terms of this Agreement without the further consent of any Debtor as contemplated by Section
8-106 (or any successor section) of the UCC. Further, no Debtor shall enter into any agreement with any person or entity other
than the Secured Parties that would confer “control”, within the meaning of Article 8 of the UCC, of any Pledged Interests.


 


(cc)          Each
Debtor shall cause all tangible chattel paper constituting Collateral to be delivered to the Agent, or, if such delivery is not
possible, then to cause such tangible chattel paper to contain a legend noting that it is subject to the security interest created
by this Agreement. To the extent that any Collateral consists of electronic chattel paper, the applicable Debtor shall cause the
underlying chattel paper to be “marked” within the meaning of Section 9-105 of the UCC (or successor section thereto).


 






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(dd)          If
there is any investment property or deposit account included as Collateral that (i) can be perfected by “control”
through an account control agreement, and (ii) at any time has a balance (in either cash or value of investment property,
or both) exceeding $25,000, the applicable Debtor shall cause such an account control agreement, in form and substance in each
case satisfactory to the Secured Parties, to be entered into and delivered to the Secured Parties, unless the Major Investors
waive the foregoing requirement with respect to any such investment property or deposit account otherwise constituting Collateral;
provided, that (x) as of the date of this Agreement, Debtor is not required to provide an account control agreement over the account
maintained by Debtor with J.P. Morgan in Germany as of the date of this Agreement (the “Germany Account”),
(y) Debtor shall notify the Agent at any time that the Germany Account has a balance (in either cash or value of investment property,
or both) exceeding $1,000,000 (a “Germany Account Notice”), and (z) Debtor shall cause an account control agreement,
in form and substance satisfactory to the Secured Parties, to be entered into and delivered to the Secured Parties in respect
of the Germany Account upon instructions from the Secured Parties to do so given by the Secured Parties to Debtor at any time
after Debtor is obligated to deliver a Germany Account Notice pursuant to the preceding clause (y).


 


(ee)          To
the extent that any Collateral consists of letter-of-credit rights, the applicable Debtor shall cause the issuer of each underlying
letter of credit to consent to an assignment of the proceeds thereof to the Secured Parties.


 


(ff)          To
the extent that any Collateral is in the possession of any third party, the applicable Debtor shall join with the Agent in notifying
such third party of the Secured Parties’ security interest in such Collateral and shall use commercially reasonable efforts
to obtain an acknowledgement and agreement from such third party with respect to the Collateral, in form and substance reasonably
satisfactory to the Agent.


 


(gg)          If
any Debtor shall at any time hold or acquire a commercial tort claim, such Debtor shall promptly notify the Secured Parties in
a writing signed by such Debtor of the particulars thereof and grant to the Secured Parties in such writing a security interest
therein and in the proceeds thereof, all upon the terms of this Agreement, with such writing to be in form and substance satisfactory
to the Agent.


 


(hh)          Each
Debtor shall immediately provide written notice to the Agent of any and all accounts which arise out of contracts with any governmental
authority and, to the extent necessary to perfect or continue the perfected status of the Security Interests in such accounts
and proceeds thereof, shall execute and deliver to the Agent an assignment of claims for such accounts and cooperate with the
Agent in taking any other steps required, in its judgment, under the Federal Assignment of Claims Act or any similar federal,
state or local statute or rule to perfect or continue the perfected status of the Security Interests in such accounts and proceeds
thereof.


 






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(ii)          Each
Debtor shall cause each wholly-owned Subsidiary that is organized in a jurisdiction within the United States to promptly become
a party hereto (an “Additional Debtor”), by executing and delivering an Additional Debtor Joinder in substantially
the form of Annex A attached hereto and comply with the provisions hereof applicable to the Debtors. Concurrent therewith,
the Additional Debtor shall deliver replacement schedules for, or supplements to all other Schedules to (or referred to in) this
Agreement, as applicable, which replacement schedules shall supersede, or supplements shall modify, the Schedules then in effect.
The Additional Debtor shall also deliver such opinions of counsel, authorizing resolutions, good standing certificates, incumbency
certificates, organizational documents, financing statements and other information and documentation as the Agent may reasonably
request. Upon delivery of the foregoing to the Agent, the Additional Debtor shall be and become a party to this Agreement with
the same rights and obligations as the Debtors, for all purposes hereof as fully and to the same extent as if it were an original
signatory hereto and shall be deemed to have made the representations, warranties and covenants set forth herein as of the date
of execution and delivery of such Additional Debtor Joinder, and all references herein to the “Debtors” shall
be deemed to include each Additional Debtor.


 


(jj)          Each
Debtor shall vote the Pledged Securities to comply with the covenants and agreements set forth herein and in the Debentures.


 


(kk)          Each
Debtor shall register the pledge of the applicable Pledged Securities on the books of such Debtor. Each Debtor shall notify each
issuer of Pledged Securities to register the pledge of the applicable Pledged Securities in the name of the Secured Parties on
the books of such issuer. Further, except with respect to certificated securities delivered to the Agent, the applicable Debtor
shall deliver to Secured Parties an acknowledgement of pledge (which, where appropriate, shall comply with the requirements of
the relevant UCC with respect to perfection by registration) signed by the issuer of the applicable Pledged Securities, which
acknowledgement shall confirm that: (a) it has registered the pledge on its books and records; and (b) at any time directed by
Secured Parties during the continuation of an Event of Default, such issuer will transfer the record ownership of such Pledged
Securities into the name of any designee of Secured Parties, will take such steps as may be necessary to effect the transfer,
and will comply with all other instructions of Secured Parties regarding such Pledged Securities without the further consent of
the applicable Debtor.


 


(ll)          In
the event that, upon an occurrence of an Event of Default, Secured Parties shall sell all or any of the Pledged Securities to
another party or parties (herein called the “Transferee”) or shall purchase or retain all or any of the Pledged
Securities, each Debtor shall, to the extent applicable: (i) deliver to the Secured Parties or the Transferee, as the case
may be, the articles of incorporation, bylaws, minute books, stock certificate books, corporate seals, deeds, leases, indentures,
agreements, evidences of indebtedness, books of account, financial records and all other Organizational Documents and records
of the Debtors and their direct and indirect subsidiaries; (ii) use its best efforts to obtain resignations of the persons then
serving as officers and directors of the Debtors and their direct and indirect subsidiaries, if so requested; and (iii) use its
best efforts to obtain any approvals that are required by any governmental or regulatory body in order to permit the sale of the
Pledged Securities to the Transferee or the purchase or retention of the Pledged Securities by the Secured Parties and allow the
Transferee or the Secured Parties to continue the business of the Debtors and their direct and indirect subsidiaries.


 






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(mm)          Without
limiting the generality of the other obligations of the Debtors hereunder, each Debtor shall promptly (i) cause to be registered
at the United States Copyright Office all of its material copyrights, (ii) cause the security interest contemplated hereby
with respect to all Intellectual Property registered at the United States Copyright Office or United States Patent and Trademark
Office to be duly recorded at the applicable office, and (iii) give the Agent notice whenever it acquires (whether absolutely
or by license) or creates any additional material Intellectual Property on a quarterly basis.


 


(nn)          Each
Debtor will from time to time, at the joint and several expense of the Debtors, promptly execute and deliver all such further
instruments and documents, and take all such further action as the Secured Parties may reasonably request, in order to perfect
and protect any security interest granted or purported to be granted hereby or to enable the Secured Parties to exercise and enforce
their rights and remedies hereunder and with respect to any Collateral or to otherwise carry out the purposes of this Agreement.


 


(oo)          Schedule
4.(oo) attached hereto lists all of the patents, patent applications, trademarks, trademark applications, registered copyrights,
and domain names owned by any of the Debtors as of the date hereof. Schedule 4.(oo) lists all material licenses in favor
of any Debtor for the use of any patents, trademarks, copyrights and domain names as of the date hereof. All United States material
patents and trademarks of the Debtors have been duly recorded at the United States Patent and Trademark Office and all material
copyrights of the Debtors have been duly recorded at the United States Copyright Office.


 


(pp)          Except
as set forth on Schedule 4.(pp) attached hereto, none of the account debtors or other persons or entities obligated on
any of the Collateral is a governmental authority covered by the Federal Assignment of Claims Act or any similar federal, state
or local statute or rule in respect of such Collateral.


 


(qq)          Until
the Obligations shall have been paid and performed in full (other than inchoate indemnification obligations), the Company covenants
that it shall promptly cause any Additional Debtor to enter into a Subsidiary Guarantee in favor of the Secured Parties in the
form of Exhibit G to the Purchase Agreement.


 


5.           Effect
of Pledge on Certain Rights. The parties hereto agree that, if any of the Collateral subject to this Agreement consists
of nonvoting equity or ownership interests (regardless of class, designation, preference or rights) that may be converted into
voting equity or ownership interests upon the occurrence of certain events (including, without limitation, upon the transfer of
all or any of the other stock or assets of the issuer), the pledge of such equity or ownership interests pursuant to this Agreement
or the enforcement of any of the Secured Parties’ rights hereunder shall not be deemed to be the type of event which would
trigger such conversion rights, notwithstanding any provisions in the Organizational Documents or agreements to which any Debtor
is subject or to which any Debtor is party.


 


6.           Defaults.
The following events shall be “Events of Default”:


 


(a)          The
occurrence of an Event of Default under the Debentures;


 






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(b)          Any
representation or warranty of any Debtor in this Agreement shall prove to have been incorrect in any material respect when made;


 


(c)          The
failure by any Debtor to observe or perform any of its obligations hereunder for ten (10) days after delivery to such Debtor of
notice of such failure by or on behalf of any Secured Party unless such default is capable of cure but cannot be cured within
such time frame and such Debtor is all commercially reasonable efforts to cure same in a timely fashion; or


 


(d)          Any
provision of this Agreement is at any time for any reason declared to be null and void, any Debtor contests the validity or enforceability
of this Agreement, any Debtor governmental authority having jurisdiction over any Debtor commences any proceeding seeking to establish
the invalidity or unenforceability of this Agreement, or any Debtor denies that any Debtor has any liability or obligation purported
to be created under this Agreement.


 


7.           Duty
To Hold In Trust.


 


(a)          Upon
the occurrence of any Event of Default and at any time thereafter that such Event of Default remains continuing, each Debtor shall,
upon receipt of any revenue, income, dividend, interest or other sums subject to the Security Interests, whether payable pursuant
to the Debentures or otherwise, or of any check, draft, note, trade acceptance or other instrument evidencing an obligation to
pay any such sum, hold the same in trust for the Secured Parties and shall forthwith endorse and transfer any such sums or instruments,
or both, to the Secured Parties, pro rata in proportion to their respective then currently outstanding principal amount of Debentures,
for application to the satisfaction of the Obligations (and if any Debentures are not outstanding, pro-rata in proportion to the
initial purchases of the remaining Debentures).


 


(b)          If
any Debtor shall become entitled to receive or shall receive any securities or other property (including, without limitation,
shares of Pledged Securities or instruments representing Pledged Securities acquired after the date hereof, or any options, warrants,
rights or other similar property or certificates representing a dividend, or any distribution in connection with any recapitalization,
reclassification or increase or reduction of capital, or issued in connection with any reorganization of such Debtor or any of
its direct or indirect subsidiaries) in respect of the Pledged Securities (whether as an addition to, in substitution of, or in
exchange for, such Pledged Securities or otherwise), such Debtor agrees to (i) accept the same as the agent of the Secured Parties;
(ii) hold the same in trust on behalf of and for the benefit of the Secured Parties; and (iii) to deliver any and all certificates
or instruments evidencing the same to Agent on or before the close of business on the fifth business day following the receipt
thereof by such Debtor, in the exact form received together with the Necessary Endorsements, to be held by Agent subject to the
terms of this Agreement as Collateral.


 






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8.           Rights
and Remedies Upon Default.


 


(a)          Upon
the occurrence of any Event of Default and at any time thereafter that such Event of Default remains continuing, the Secured Parties,
acting through the Agent, shall have the right to exercise all of the remedies conferred hereunder and under the Debentures, and
the Secured Parties, shall have all the rights and remedies of a secured party under the UCC. Without limitation, the Agent, for
the benefit of the Secured Parties, shall have the following rights and powers:


 


(i)          The
Agent shall have the right to take possession of the Collateral and, for that purpose, enter, with the aid and assistance of any
person, any premises where the Collateral, or any part thereof, is or may be placed and remove the same, and each Debtor shall
assemble the Collateral and make it available to the Agent at places which the Agent shall reasonably select, whether at such
Debtor’s premises or elsewhere, and make available to the Agent, without rent, all of such Debtor’s respective premises
and facilities for the purpose of the Agent taking possession of, removing or putting the Collateral in saleable or disposable
form.


 


(ii)          Upon
notice to the Debtors by Agent, all rights of each Debtor to exercise the voting and other consensual rights which it would otherwise
be entitled to exercise and all rights of each Debtor to receive the dividends and interest which it would otherwise be authorized
to receive and retain, shall cease. Upon such notice, Agent shall have the right to receive, for the ratable benefit of the Secured
Parties, any interest, cash dividends or other payments on the Collateral and, at the option of Agent, to exercise in such Agent’s
discretion all voting rights pertaining thereto. Without limiting the generality of the foregoing, Agent shall have the right
(but not the obligation) to exercise all rights with respect to the Collateral as it were the sole and absolute owner thereof,
including, without limitation, to vote and/or to exchange, at its sole discretion, any or all of the Collateral in connection
with a merger, reorganization, consolidation, recapitalization or other readjustment concerning or involving the Collateral or
any Debtor or any of its direct or indirect subsidiaries.


 


(iii)          The
Agent shall have the right to use the Collateral and shall have the right to assign, sell, lease or otherwise dispose of and deliver
all or any part of the Collateral, at public or private sale or otherwise, either with or without special conditions or stipulations,
for cash or on credit or for future delivery, in such parcel or parcels and at such time or times and at such place or places,
and upon such terms and conditions as the Agent may deem commercially reasonable, all without (except as shall be required by
applicable statute and cannot be waived) advertisement or demand upon or notice to any Debtor or right of redemption of a Debtor,
which are hereby expressly waived. Upon each such sale, lease, assignment or other transfer of Collateral, the Agent, for the
ratable benefit of the Secured Parties, may, unless prohibited by applicable law which cannot be waived, purchase all or any part
of the Collateral being sold, free from and discharged of all trusts, claims, right of redemption and equities of any Debtor,
which are hereby waived and released.


 






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(iv)          The
Agent shall have the right (but not the obligation) to notify any account debtors and any obligors under instruments or accounts
to make payments directly to the Agent, for the ratable benefit of the Secured Parties, and to enforce the Debtors’ rights
against such account debtors and obligors.


 


(v)          The
Agent may (but is not obligated to) direct any financial intermediary or any other person or entity holding any investment property
to transfer the same to the Agent (or the Agent’s designee), for the ratable benefit of the Secured Parties.


 


(vi)          The
Agent may (but is not obligated to) transfer any or all Intellectual Property registered in the name of any Debtor at the United
States Patent and Trademark Office and/or Copyright Office into the name of the Secured Parties or any designee or any purchaser
of any Collateral.


 


(b)          The
Agent shall comply with any applicable law in connection with a disposition of Collateral and such compliance will not be considered
adversely to affect the commercial reasonableness of any sale of the Collateral. The Agent may sell the Collateral without giving
any warranties and may specifically disclaim such warranties. If the Agent sells any of the Collateral on credit, the Debtors
will only be credited with payments actually made by the purchaser. In addition, each Debtor waives any and all rights that it
may have to a judicial hearing in advance of the enforcement of any of the Agent’s rights and remedies hereunder, including,
without limitation, its right following an Event of Default to take immediate possession of the Collateral and to exercise its
rights and remedies with respect thereto.


 


(c)          For
the purpose of enabling the Agent to further exercise rights and remedies under this Section 8 or elsewhere provided by agreement
or applicable law, each Debtor hereby grants to the Agent, for the ratable benefit of the Secured Parties an irrevocable, nonexclusive
license (exercisable without payment of royalty or other compensation to such Debtor) to use, license or sublicense following
an Event of Default, any Intellectual Property now owned or hereafter acquired by such Debtor, and wherever the same may be located,
and including in such license access to all media in which any of the licensed items may be recorded or stored and to all computer
software and programs used for the compilation or printout thereof.


 


(d)          Notwithstanding
anything in this Agreement to the contrary, each Secured Party agrees that it will not, and will not authorize the Agent to, exercise
any remedy provided for under this Agreement with respect to all or any portion of the Collateral unless such Secured Party is
a Permitted Secured Party (provided that the foregoing shall not prevent any Secured Party from commencing or participating in
any Insolvency Proceeding or taking any action (other than with respect to the Collateral) to enforce the payment or performance
of any Debtor’s obligations under any of the Debentures or other Transaction Documents). This Section 8(d) is not
intended to confer any rights or benefits upon the Debtors, or any of them, or any other Person except Secured Parties, and no
Person (including any or all Debtors) other than Secured Parties shall have any right to enforce any of the provisions of this
Section 8(d). As between the Debtors, or any of them, and any Secured Party, any action that such Secured Party may take
under this Agreement shall be conclusively presumed to have been authorized and approved by the other Secured Parties.


 






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9.          Applications
of Proceeds. The proceeds of any such sale, lease or other disposition of the Collateral hereunder or from payments made on
account of any insurance policy insuring any portion of the Collateral shall be applied first, to the expenses of retaking, holding,
storing, processing and preparing for sale, selling, and the like (including, without limitation, any taxes, fees and other costs
incurred in connection therewith) of the Collateral, to the reasonable attorneys’ fees and expenses incurred by the Agent
in enforcing the Secured Parties’ rights hereunder and in connection with collecting, storing and disposing of the Collateral,
and then to satisfaction of the Obligations pro rata among the Secured Parties (based on then-outstanding principal amounts of
Debentures at the time of any such determination), and to the payment of any other amounts required by applicable law, after which
the Secured Parties shall pay to the applicable Debtor any surplus proceeds. If, upon the sale, license or other disposition of
the Collateral, the proceeds thereof are insufficient to pay all amounts to which the Secured Parties are legally entitled, the
Debtors will be liable for the deficiency, together with interest thereon, at the rate of 12% per annum or the lesser amount permitted
by applicable law (the “Default Rate”), and the reasonable fees of any attorneys employed by the Secured Parties
to collect such deficiency. To the extent permitted by applicable law, each Debtor waives all claims, damages and demands against
the Secured Parties arising out of the repossession, removal, retention or sale of the Collateral, unless due solely to the gross
negligence or willful misconduct of the Secured Parties as determined by a final judgment (not subject to further appeal) of a
court of competent jurisdiction.


 


10.          Securities
Law Provision. Each Debtor recognizes that Secured Parties may be limited in their ability to effect a sale to the
public of all or part of the Pledged Securities by reason of certain prohibitions in the Securities Act of 1933, as amended, or
other federal or state securities laws (collectively, the “Securities Laws”), and may be compelled to resort
to one or more sales to a restricted group of purchasers who may be required to agree to acquire the Pledged Securities for their
own account, for investment and not with a view to the distribution or resale thereof. Each Debtor agrees that sales so made may
be at prices and on terms less favorable than if the Pledged Securities were sold to the public, and that the Secured Parties
have no obligation to delay the sale of any Pledged Securities for the period of time necessary to register the Pledged Securities
for sale to the public under the Securities Laws. Each Debtor shall cooperate with Secured Parties in its attempt to satisfy any
requirements under the Securities Laws (including, without limitation, registration thereunder if requested by Agent) applicable
to the sale of the Pledged Securities by Agent.


 


11.          Costs
and Expenses. Each Debtor agrees to pay all reasonable out-of-pocket fees, costs and expenses incurred in connection with
any filing required hereunder, including without limitation, any financing statements pursuant to the UCC, continuation statements,
partial releases and/or termination statements related thereto or any expenses of any searches reasonably required by the Agent.
The Debtors will also, upon demand, pay to the Agent the amount of any and all reasonable expenses, including the reasonable fees
and expenses of its counsel, which the Agent, for the benefit of the Secured Parties, may incur in connection with the creation,
perfection, protection, foreclosure, collection or enforcement of the Security Interest and the preparation, administration, continuance,
amendment or enforcement of this Agreement and pay to the Agent the amount of any and all reasonable expenses, including the reasonable
fees and expenses of its counsel, which the Agent, for the benefit of the Secured Parties, and the Secured Parties may incur in
connection with (i) the enforcement of this Agreement, (ii) the custody or preservation of, or the sale of, collection from, or
other realization upon, any of the Collateral, or (iii) the exercise or enforcement of any of the rights of the Secured Parties
under the Debentures. Until so paid, any fees payable hereunder shall be added to the principal amount of the Debentures and shall
bear interest at the Default Rate.


 






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12.          Responsibility
for Collateral. The Debtors assume all liabilities and responsibility in connection with all Collateral, and the Obligations
shall in no way be affected or diminished by reason of the loss, destruction, damage or theft of any of the Collateral or its
unavailability for any reason. Without limiting the generality of the foregoing, (a) neither the Agent nor any Secured Party (i)
has any duty (either before or after an Event of Default) to collect any amounts in respect of the Collateral or to preserve any
rights relating to the Collateral, or (ii) has any obligation to clean-up or otherwise prepare the Collateral for sale, and (b)
each Debtor shall remain obligated and liable under each contract or agreement included in the Collateral to be observed or performed
by such Debtor thereunder. Neither the Agent nor any Secured Party shall have any obligation or liability under any such contract
or agreement by reason of or arising out of this Agreement or the receipt by the Agent or any Secured Party of any payment relating
to any of the Collateral, nor shall the Agent or any Secured Party be obligated in any manner to perform any of the obligations
of any Debtor under or pursuant to any such contract or agreement, to make inquiry as to the nature or sufficiency of any payment
received by the Agent or any Secured Party in respect of the Collateral or as to the sufficiency of any performance by any party
under any such contract or agreement, to present or file any claim, to take any action to enforce any performance or to collect
the payment of any amounts which may have been assigned to the Agent or to which the Agent or any Secured Party may be entitled
at any time or times.


 


13.          Security
Interests Absolute. All rights of the Secured Parties and all of the Obligations are absolute and unconditional, irrespective
of: (a) any lack of validity or enforceability of this Agreement, the Debentures or any agreement entered into in connection with
the foregoing, or any portion hereof or thereof; (b) any change in the time, manner or place of payment or performance of, or
in any other term of, all or any of the Obligations, or any other amendment or waiver of or any consent to any departure from
the Debentures or any other agreement entered into in connection with the foregoing; (c) any exchange, release or nonperfection
of any of the Collateral, or any release or amendment or waiver of or consent to departure from any other collateral for, or any
guarantee, or any other security, for all or any of the Obligations; (d) any action by the Secured Parties to obtain, adjust,
settle and cancel in its sole discretion any insurance claims or matters made or arising in connection with the Collateral; or
(e) any other circumstance which might otherwise constitute any legal or equitable defense available to a Debtor, or a discharge
of all or any part of the Security Interests granted hereby. Until the Obligations shall have been paid and performed in full
(other than inchoate indemnification obligations), the rights of the Secured Parties shall continue even if the Obligations are
barred for any reason, including, without limitation, the running of the statute of limitations or bankruptcy. Each Debtor expressly
waives presentment, protest, notice of protest, demand, notice of nonpayment and demand for performance. In the event that at
any time any transfer of any Collateral or any payment received by the Secured Parties hereunder shall be deemed by final order
of a court of competent jurisdiction to have been a voidable preference or fraudulent conveyance under the bankruptcy or insolvency
laws of the United States, or shall be deemed to be otherwise due to any party other than the Secured Parties, then, in any such
event, each Debtor’s obligations hereunder shall survive cancellation of this Agreement, and shall not be discharged or
satisfied by any prior payment thereof and/or cancellation of this Agreement, but shall remain a valid and binding obligation
enforceable in accordance with the terms and provisions hereof. Each Debtor waives all right to require the Secured Parties to
proceed against any other person or entity or to apply any Collateral which the Secured Parties may hold at any time, or to marshal
assets, or to pursue any other remedy.


 






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14.          Term
of Agreement. This Agreement and the Security Interests shall terminate on the date on which all payments under the Debentures
have been paid in full and all other Obligations have been paid or discharged (other than inchoate indemnification obligations);
provided, however, that all indemnities of the Debtors contained in this Agreement (including, without limitation,
Annex B hereto) shall survive and remain operative and in full force and effect regardless of the termination of this Agreement.


 


15.          Power
of Attorney; Further Assurances.


 


(a)          Each
Debtor authorizes the Agent, and does hereby make, constitute and appoint the Agent and its officers, agents, successors or assigns
with full power of substitution, as such Debtor’s true and lawful attorney-in-fact, with power, in the name of the Agent
or such Debtor, to, after the occurrence and during the continuance of an Event of Default, (i) endorse any note, checks, drafts,
money orders or other instruments of payment (including payments payable under or in respect of any policy of insurance) in respect
of the Collateral that may come into possession of the Agent; (ii) to sign and endorse any financing statement pursuant to the
UCC or any invoice, freight or express bill, bill of lading, storage or warehouse receipts, drafts against debtors, assignments,
verifications and notices in connection with accounts, and other documents relating to the Collateral; (iii) to pay or discharge
taxes, liens, security interests or other encumbrances at any time levied or placed on or threatened against the Collateral; (iv)
to demand, collect, receipt for, compromise, settle and sue for monies due in respect of the Collateral; (v) to transfer any Intellectual
Property or provide licenses respecting any Intellectual Property; and (vi) generally, at the option of the Agent, and at the
expense of the Debtors, at any time, or from time to time, to execute and deliver any and all documents and instruments and to
do all acts and things which the Agent deems necessary to protect, preserve and realize upon the Collateral and the Security Interests
granted therein in order to effect the intent of this Agreement and the Debentures all as fully and effectually as the Debtors
might or could do; and each Debtor hereby ratifies all that said attorney shall lawfully do or cause to be done by virtue hereof.
This power of attorney is coupled with an interest and shall be irrevocable for the term of this Agreement and thereafter as long
as any of the Obligations (other than inchoate indemnification obligations) shall be outstanding. The designation set forth herein
shall be deemed to amend and supersede any inconsistent provision in the Organizational Documents or other documents or agreements
to which any Debtor is subject or to which any Debtor is a party. Without limiting the generality of the foregoing, after the
occurrence and during the continuance of an Event of Default, each Secured Party is specifically authorized to execute and file
any applications for or instruments of transfer and assignment of any patents, trademarks, copyrights or other Intellectual Property
with the United States Patent and Trademark Office and the United States Copyright Office.


 






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(b)          On
a continuing basis, each Debtor will make, execute, acknowledge, deliver, file and record, as the case may be, with the proper
filing and recording agencies in any jurisdiction, including, without limitation, the jurisdictions indicated on Schedule 4.(y)
attached hereto, all such instruments, and take all such action as may reasonably be requested by the Agent, to perfect the
Security Interests granted hereunder and otherwise to carry out the intent and purposes of this Agreement, or for assuring and
confirming to the Agent the grant or perfection of a perfected security interest in all the Collateral under the UCC.


 


(c)          Each
Debtor hereby irrevocably appoints the Agent as such Debtor’s attorney-in-fact, with full authority in the place and instead
of such Debtor and in the name of such Debtor, from time to time in the Agent’s discretion, to take any action and to execute
any instrument which the Agent may deem necessary or advisable to accomplish the purposes of this Agreement, including the filing,
in its sole discretion, of one or more financing or continuation statements and amendments thereto, relative to any of the Collateral
without the signature of such Debtor where permitted by law, which financing statements may (but need not) describe the Collateral
as “all assets” or “all personal property” or words of like import, and ratifies all such actions taken
by the Agent. This power of attorney is coupled with an interest and shall be irrevocable for the term of this Agreement and thereafter
as long as any of the Obligations shall be outstanding.


 


16.          Notices.
All notices, requests, demands and other communications hereunder shall be subject to the notice provision of the Purchase Agreement.


 


17.          Other
Security. To the extent that the Obligations are now or hereafter secured by property other than the Collateral or by the
guarantee, endorsement or property of any other person, firm, corporation or other entity, then the Agent shall have the right,
in its sole discretion, to pursue, relinquish, subordinate, modify or take any other action with respect thereto, without in any
way modifying or affecting any of the Secured Parties’ rights and remedies hereunder.


 


18.          Appointment
of Agent. The Secured Parties hereby appoint Sabby Management, LLC (“Sabby”) to act as their agent
(in such capacity, the “Agent”) for purposes of exercising any and all rights and remedies of the Secured Parties
hereunder. Such appointment shall continue until revoked in writing by a Majority in Interest, at which time a Majority in Interest
shall appoint a new Agent, provided that Sabby may not be removed as Agent unless Sabby Volatility Warrant Master Fund, Ltd. and
Sabby Healthcare Master Fund, Ltd., in the aggregate, then hold less than $1,000,000 in principal amount of Debentures; provided,
further, that such removal may occur only if the other Secured Parties then hold, in the aggregate, not less than an aggregate
of $1,000,000 in principal amount of Debentures. The Agent has the rights, responsibilities and immunities set forth in Annex
B hereto.


 






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19.          Miscellaneous.


 


(a)          No
course of dealing between the Debtors, on the one hand, and the Secured Parties, on the other hand, nor any failure to exercise,
nor any delay in exercising, on the part of the Secured Parties, any right, power or privilege hereunder or under the Debentures
shall operate as a waiver thereof; nor shall any single or partial exercise of any right, power or privilege hereunder or thereunder
preclude any other or further exercise thereof or the exercise of any other right, power or privilege.


 


(b)          All
of the rights and remedies of the Secured Parties with respect to the Collateral, whether established hereby or by the Debentures
or by any other agreements, instruments or documents or by law shall be cumulative and may be exercised singly or concurrently.


 


(c)          This
Agreement, together with the exhibits and schedules hereto, contain the entire understanding of the parties with respect to the
subject matter hereof and supersede all prior agreements and understandings, oral or written, with respect to such matters, which
the parties acknowledge have been merged into this Agreement and the exhibits and schedules hereto. No provision of this Agreement
may be waived, modified, supplemented or amended except in a written instrument signed, in the case of an amendment, by the Debtors
and the Secured Parties holding 67% or more of the principal amount of Debentures then outstanding, or, in the case of a waiver,
by the party against whom enforcement of any such waived provision is sought; provided, however, unanimous consent
shall be required for any amendment that would adversely affect any Secured Parties.


 


(d)          If
any term, provision, covenant or restriction of this Agreement is held by a court of competent jurisdiction to be invalid, illegal,
void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein shall remain in full
force and effect and shall in no way be affected, impaired or invalidated, and the parties hereto shall use their commercially
reasonable efforts to find and employ an alternative means to achieve the same or substantially the same result as that contemplated
by such term, provision, covenant or restriction. It is hereby stipulated and declared to be the intention of the parties that
they would have executed the remaining terms, provisions, covenants and restrictions without including any of such that may be
hereafter declared invalid, illegal, void or unenforceable.


 


(e)          No
waiver of any default with respect to any provision, condition or requirement of this Agreement shall be deemed to be a continuing
waiver in the future or a waiver of any subsequent default or a waiver of any other provision, condition or requirement hereof,
nor shall any delay or omission of any party to exercise any right hereunder in any manner impair the exercise of any such right.


 






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(f)          This
Agreement shall be binding upon and inure to the benefit of the parties and their successors and permitted assigns. No Debtor
may assign this Agreement or any rights or obligations hereunder without the prior written consent of each Secured Party (other
than by merger). Any Secured Party may assign any or all of its rights under this Agreement to any Person (as defined in the Purchase
Agreement) to whom such Secured Party assigns or transfers any Obligations, provided such transferee agrees in writing to be bound,
with respect to the transferred Obligations, by the provisions of this Agreement that apply to the “Secured Parties.”


 


(g)          Each
party shall take such further action and execute and deliver such further documents as may be necessary or appropriate in order
to carry out the provisions and purposes of this Agreement.


 


(h)          Except
to the extent mandatorily governed by the jurisdiction or situs where the Collateral is located, all questions concerning the
construction, validity, enforcement and interpretation of this Agreement shall be governed by and construed and enforced in accordance
with the internal laws of the State of New York, without regard to the principles of conflicts of law thereof. Except to the extent
mandatorily governed by the jurisdiction or situs where the Collateral is located, each Debtor agrees that all proceedings concerning
the interpretations, enforcement and defense of the transactions contemplated by this Agreement and the Debentures (whether brought
against a party hereto or its respective affiliates, directors, officers, shareholders, partners, members, employees or agents)
shall be commenced exclusively in the state and federal courts sitting in the City of New York, Borough of Manhattan. Except to
the extent mandatorily governed by the jurisdiction or situs where the Collateral is located, each Debtor hereby irrevocably submits
to the exclusive jurisdiction of the state and federal courts sitting in the City of New York, Borough of Manhattan for the adjudication
of any dispute hereunder or in connection herewith or with any transaction contemplated hereby or discussed herein, and hereby
irrevocably waives, and agrees not to assert in any proceeding, any claim that it is not personally subject to the jurisdiction
of any such court, that such proceeding is improper. Each party hereto hereby irrevocably waives personal service of process and
consents to process being served in any such proceeding by mailing a copy thereof via registered or certified mail or overnight
delivery (with evidence of delivery) to such party at the address in effect for notices to it under this Agreement and agrees
that such service shall constitute good and sufficient service of process and notice thereof. Nothing contained herein shall be
deemed to limit in any way any right to serve process in any manner permitted by law. Each party hereto hereby irrevocably waives,
to the fullest extent permitted by applicable law, any and all right to trial by jury in any legal proceeding arising out of or
relating to this Agreement or the transactions contemplated hereby.


 


(i)          This
Agreement may be executed in any number of counterparts, each of which when so executed shall be deemed to be an original and,
all of which taken together shall constitute one and the same Agreement. In the event that any signature is delivered by facsimile
transmission, such signature shall create a valid binding obligation of the party executing (or on whose behalf such signature
is executed) the same with the same force and effect as if such facsimile signature were the original thereof.


 






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(j)          All
Debtors shall jointly and severally be liable for the obligations of each Debtor to the Secured Parties hereunder.


 


(k)          Each
Debtor shall indemnify, reimburse and hold harmless the Agent and the Secured Parties and their respective partners, members,
shareholders, officers, directors, employees and agents (and any other persons with other titles that have similar functions)
(collectively, “Indemnitees”) from and against any and all losses, claims, liabilities, damages, penalties,
suits, costs and expenses, of any kind or nature, (including fees relating to the cost of investigating and defending any of the
foregoing) imposed on, incurred by or asserted against such Indemnitee in any way related to or arising from or alleged to arise
from this Agreement or the Collateral, except any such losses, claims, liabilities, damages, penalties, suits, costs and expenses
which result from the gross negligence or willful misconduct of the Indemnitee as determined by a final, nonappealable decision
of a court of competent jurisdiction. This indemnification provision is in addition to, and not in limitation of, any other indemnification
provision in the Debentures, the Purchase Agreement or any other agreement, instrument or other document executed or delivered
in connection herewith or therewith.


 


(l)          Nothing
in this Agreement shall be construed to subject Agent or any Secured Party to liability as a partner in any Debtor or any of its
direct or indirect subsidiaries that is a partnership or as a member in any Debtor or any of its direct or indirect subsidiaries
that is a limited liability company, nor shall Agent or any Secured Party be deemed to have assumed any obligations under any
partnership agreement or limited liability company agreement, as applicable, of any such Debtor or any of its direct or indirect
subsidiaries or otherwise, unless and until the any such Secured Party exercises its right to be substituted for such Debtor as
a partner or member, as applicable, pursuant hereto.


 


(m)          To
the extent that the grant of the security interest in the Collateral and the enforcement of the terms hereof require the consent,
approval or action of any partner or member, as applicable, of any Debtor or any direct or indirect subsidiary of any Debtor or
compliance with any provisions of any of the Organizational Documents, the Debtors hereby grant such consent and approval and
waive any such noncompliance with the terms of said documents.


 


[SIGNATURE
PAGES FOLLOW]


 






    	24



    	 



    

 


IN
WITNESS WHEREOF, the parties hereto have caused this Amended and Restated Security Agreement to be duly executed on the day and
year first above written.  


	 	 
	 	MELA SCIENCES, INC.
	 	 
	 	By: 
	 	 	Michael
                                         R. Stewart


Chief
Executive Officer





  


[SIGNATURE
PAGES OF SECURED PARTIES FOLLOW]


 






    	[Signature Page to Amended and Restated Security Agreement]








    	 



    

 


[SIGNATURE
PAGE OF SECURED PARTY TO MELA AMENDED AND RESTATED SECURITY AGREEMENT]





	 	 
	Name of Investing Entity: 	 






	 	 
	Signature of Authorized Signatory of Investing Entity:  	 






	 	 
	Name of Authorized Signatory:  	 






	 	 
	Title of Authorized Signatory:  	 



 






    	 



    	 



    




 


SCHEDULE
4.(b)


 


Principal
Place of Business of Debtors:


 


Locations
Where Collateral is Located or Stored:


 






    	 



    	 



    

  


SCHEDULE
4.(c)


 


Financing
Statements


 






    	 



    	 



    

 


SCHEDULE
4.(i)


 


Subsidiary
Equity Interests


 






    	 



    	 



    

  


SCHEDULE
4.(y)


 


Legal
Names and Organizational Identification Numbers


 






    	 



    	 



    

  


SCHEDULE
4.(z)


 


Names;
Mergers and Acquisitions


 






    	 



    	 



    

 


SCHEDULE
4.(oo)


 


Intellectual
Property


 






    	 



    	 



    

  


SCHEDULE
4.(pp)


 


Account
Debtors


 






    	 



    	 



    

 


ANNEX
A


to


SECURITY


AGREEMENT


 


FORM
OF ADDITIONAL DEBTOR JOINDER


 


to
that certain Amended and Restated Security Agreement dated as of July [●], 2015 made by MELA Sciences, Inc. (the “Company”)
and its subsidiaries party thereto from time to time, as Debtors, to and in favor of the Secured Parties identified therein (the
“Security Agreement”), relating to the Company’s 4% Senior Secured Convertible Debentures due July 24,
2019


 


Reference
is made to the Security Agreement as defined above; capitalized terms used herein and not otherwise defined herein shall have
the meanings given to such terms in, or by reference in, the Security Agreement.


 


The
undersigned hereby agrees that upon delivery of this Additional Debtor Joinder to the Secured Parties referred to above, the undersigned
shall (a) be an Additional Debtor under the Security Agreement, (b) have all the rights and obligations of the Debtors under the
Security Agreement as fully and to the same extent as if the undersigned was an original signatory thereto and (c) be deemed to
have made the representations and warranties set forth therein as of the date of execution and delivery of this Additional Debtor
Joinder. WITHOUT LIMITING THE GENERALITY OF THE FOREGOING, THE UNDERSIGNED SPECIFICALLY GRANTS TO THE SECURED PARTIES, A SECURITY
INTEREST IN THE COLLATERAL AS MORE FULLY SET FORTH IN THE SECURITY AGREEMENT AND ACKNOWLEDGES AND AGREES TO THE WAIVER OF JURY
TRIAL PROVISIONS SET FORTH THEREIN.


 


Attached
hereto are supplemental and/or replacement Schedules to the Security Agreement, as applicable.


 


The
undersigned shall deliver an executed copy of this Joinder to the Secured Parties, and the Secured Parties may rely on the matters
set forth herein on or after the date hereof. This Joinder shall not be modified, amended or terminated without the prior written
consent of the Secured Parties.


 






    	 



    	 



    

 


IN
WITNESS WHEREOF, the undersigned has caused this Joinder to be executed in the name and on behalf of the undersigned. 


	 	 
	 	[INSERT NAMES OF ADDITIONAL DEBTORS]
	 	 
	 	By: 
	 	 	Name:


Title:



	 	 	 
	 	Dated:       ______
    __, 20__



 






    	 



    	 



    

   


ANNEX
B


to


SECURITY


AGREEMENT


 


THE
AGENT


 


1.
Appointment. The Secured Parties (all capitalized terms used herein and not otherwise defined shall have the respective
meanings provided in the Amended and Restated Security Agreement to which this Annex B is attached (the “Agreement”)),
by their acceptance of the benefits of the Agreement, hereby designate Sabby Management, LLC (“Sabby”) as the
Agent to act as specified herein and in the Agreement. Each Secured Party shall be deemed irrevocably to authorize the Agent to
take such action on its behalf under the provisions of the Agreement and any other Transaction Document (as such term is defined
in the Purchase Agreement) and to exercise such powers and to perform such duties hereunder and thereunder as are specifically
delegated to or required of the Agent by the terms hereof and thereof and such other powers as are reasonably incidental thereto.
The Agent may perform any of its duties hereunder by or through its agents or employees.


 


2.
Nature of Duties. The Agent shall have no duties or responsibilities except those expressly set forth in the Agreement.
Neither the Agent nor any of its partners, members, shareholders, officers, directors, employees or agents shall be liable for
any action taken or omitted by it as such under the Agreement or hereunder or in connection herewith or therewith, be responsible
for the consequence of any oversight or error of judgment or answerable for any loss, unless caused solely by its or their gross
negligence or willful misconduct as determined by a final judgment (not subject to further appeal) of a court of competent jurisdiction.
The duties of the Agent shall be mechanical and administrative in nature; the Agent shall not have by reason of the Agreement
or any other Transaction Document a fiduciary relationship in respect of any Debtor or any Secured Party; and nothing in the Agreement
or any other Transaction Document, expressed or implied, is intended to or shall be so construed as to impose upon the Agent any
obligations in respect of the Agreement or any other Transaction Document except as expressly set forth herein and therein.


 


3.
Lack of Reliance on the Agent. Independently and without reliance upon the Agent, each Secured Party, to the extent it
deems appropriate, has made and shall continue to make (i) its own independent investigation of the financial condition and affairs
of the Company and its subsidiaries in connection with such Secured Party’s investment in the Debtors, the creation and
continuance of the Obligations, the transactions contemplated by the Transaction Documents, and the taking or not taking of any
action in connection therewith, and (ii) its own appraisal of the creditworthiness of the Company and its subsidiaries, and of
the value of the Collateral from time to time, and the Agent shall have no duty or responsibility, either initially or on a continuing
basis, to provide any Secured Party with any credit, market or other information with respect thereto, whether coming into its
possession before any Obligations are incurred or at any time or times thereafter. The Agent shall not be responsible to the Debtors
or any Secured Party for any recitals, statements, information, representations or warranties herein or in any document, certificate
or other writing delivered in connection herewith, or for the execution, effectiveness, genuineness, validity, enforceability,
perfection, collectability, priority or sufficiency of the Agreement or any other Transaction Document, or for the financial condition
of the Debtors or the value of any of the Collateral, or be required to make any inquiry concerning either the performance or
observance of any of the terms, provisions or conditions of the Agreement or any other Transaction Document, or the financial
condition of the Debtors, or the value of any of the Collateral, or the existence or possible existence of any default or Event
of Default under the Agreement, the Debentures or any of the other Transaction Documents.


 






    	 



    	 



    

 


4.
Certain Rights of the Agent. The Agent shall have the right to take any action with respect to the Collateral, on behalf
of all of the Secured Parties. To the extent practical, the Agent shall request instructions from the Secured Parties with respect
to any material act or action (including failure to act) in connection with the Agreement or any other Transaction Document, and
shall be entitled to act or refrain from acting in accordance with the instructions of a Majority in Interest; if such instructions
are not provided despite the Agent’s request therefor, the Agent shall be entitled to refrain from such act or taking such
action, and if such action is taken, shall be entitled to appropriate indemnification from the Secured Parties in respect of actions
to be taken by the Agent; and the Agent shall not incur liability to any person or entity by reason of so refraining. Without
limiting the foregoing, (a) no Secured Party shall have any right of action whatsoever against the Agent as a result of the Agent
acting or refraining from acting hereunder in accordance with the terms of the Agreement or any other Transaction Document, and
the Debtors shall have no right to question or challenge the authority of, or the instructions given to, the Agent pursuant to
the foregoing and (b) the Agent shall not be required to take any action which the Agent believes (is) could reasonably be expected
to expose it to personal liability or (ii) is contrary to this Agreement, the Transaction Documents or applicable law.


 


5.
Reliance. The Agent shall be entitled to rely, and shall be fully protected in relying, upon any writing, resolution, notice,
statement, certificate, telex, e-mail or telecopy message, cablegram, radiogram, order or other document or telephone message
signed, sent or made by the proper person or entity, and, with respect to all legal matters pertaining to the Agreement and the
other Transaction Documents and its duties thereunder, upon advice of counsel selected by it and upon all other matters pertaining
to this Agreement and the other Transaction Documents and its duties thereunder, upon advice of other experts selected by it.
Anything to the contrary notwithstanding, the Agent shall have no obligation whatsoever to any Secured Party to assure that the
Collateral exists or is owned by the Debtors or is cared for, protected or insured or that the liens granted pursuant to the Agreement
have been properly or sufficiently or lawfully created, perfected, or enforced or are entitled to any particular priority.


 


6.
Indemnification. To the extent that the Agent is not reimbursed and indemnified by the Debtors, the Secured Parties
will jointly and severally reimburse and indemnify the Agent, in proportion to their principal amounts of Debentures then held,
from and against any and all liabilities, obligations, losses, damages, penalties, actions, judgments, suits, costs, expenses
or disbursements of any kind or nature whatsoever which may be imposed on, incurred by or asserted against the Agent in performing
its duties hereunder or under the Agreement or any other Transaction Document, or in any way relating to or arising out of the
Agreement or any other Transaction Document except for those determined by a final judgment (not subject to further appeal) of
a court of competent jurisdiction to have resulted solely from the Agent’s own gross negligence or willful misconduct. Prior
to taking any action hereunder as Agent, the Agent may require each Secured Party to deposit with it sufficient sums as it determines
in good faith is necessary to protect the Agent for costs and expenses associated with taking such action.


 






    	 



    	 



    

 


7.
Resignation by the Agent.


 


(a)
The Agent may resign from the performance of all its functions and duties under the Agreement and the other Transaction Documents
at any time by giving 30 days’ prior written notice (as provided in the Agreement) to the Debtors and the Secured Parties.
Such resignation shall take effect upon the appointment of a successor Agent pursuant to clauses (b) and (c) below.


 


(b)
Upon any such notice of resignation, the Secured Parties, acting by a Majority in Interest, shall appoint a successor Agent
hereunder.


 


(c)
If a successor Agent shall not have been so appointed within said 30-day period, the Agent shall then appoint a successor Agent
who shall serve as Agent until such time, if any, as the Secured Parties appoint a successor Agent as provided above. If a successor
Agent has not been appointed within such 30-day period, the Agent may petition any court of competent jurisdiction or may interplead
the Debtors and the Secured Parties in a proceeding for the appointment of a successor Agent, and all fees, including, but not
limited to, extraordinary fees associated with the filing of interpleader and expenses associated therewith, shall be payable
by the Debtors on demand.


 


8.
Rights with respect to Collateral. Each Secured Party agrees with all other Secured Parties and the Agent (i) that
it shall not, and shall not attempt to, exercise any rights with respect to its security interest in the Collateral, whether pursuant
to any other agreement or otherwise (other than pursuant to this Agreement), or take or institute any action against the Agent
or any of the other Secured Parties in respect of the Collateral or its rights hereunder (other than any such action arising from
the breach of this Agreement) and (ii) that such Secured Party has no other rights with respect to the Collateral other than as
set forth in this Agreement and the other Transaction Documents. Upon the acceptance of any appointment as Agent hereunder by
a successor Agent, such successor Agent shall thereupon succeed to and become vested with all the rights, powers, privileges and
duties of the retiring Agent and the retiring Agent shall be discharged from its duties and obligations under the Agreement. After
any retiring Agent’s resignation or removal hereunder as Agent, the provisions of the Agreement including this Annex B shall
inure to its benefit as to any actions taken or omitted to be taken by it while it was Agent.