EX-10.10



 Exhibit 10.10 
  





 
 December 23, 2014 

Dr. Michele Trucksis 
 12 Forest Hill Road 

Wayland, MA 01778 
 Dear Dr. Trucksis, 

Seres Health, Inc. (the “Company”) is pleased to confirm its offer to employ you as a regular, full-time employee on the following terms:

 1. Position; start date. You will serve as the Company’s Chief Medical Officer and Executive Vice President. In this capacity
you will be reporting to Roger Pomerantz, Chief Executive Officer. Your effective date of hire will be no later than January 15th, 2015. This letter is subject to, and will become effective only upon, your commencing employment with the Company
(the date you actually commence employment, the “Effective Date”). 
 2. Base salary; work location. Your base
salary for this position will be at the rate of $320,000 per year. Your base salary will be paid semi-monthly in equal installments and in accordance with the Company’s payroll practices and procedures. Your normal place of work will be 161
First Street, Suite 2C, Cambridge, Massachusetts 02142; however, it is understood that the Company may change your normal place of work according to the Company’s future needs. 

3. Annual bonus. Beginning with the 2015 fiscal year, you will be eligible to receive an annual bonus with a target amount equal to 30%
of your annual base salary, with the actual amount of any such bonus determined at the sole discretion of the Company’s Board of Directors or an authorized committee thereof (the “Board”) based upon both the Company’s
performance and your individual performance and subject to proration for any partial year of service. Bonuses are intended to retain valuable Company employees, and a bonus is not payable unless you are an employee of the Company on the date that
such bonus is paid. 
 4. Signing bonus. The Company will pay you a one-time signing bonus in the amount of $40,000 (the
“Signing Bonus”), payable on the Company’s first ordinary payroll date following your start date and provided you remain continuously employed with the Company through the payment date. In the event that you voluntarily
terminate your employment with the Company (other than for Good Reason, as defined below) prior to the first anniversary of the Effective Date, you agree to repay to the Company a pro-rata portion of the Signing Bonus, which pro-rata amount will be
determined by multiplying the Signing Bonus by a fraction, the numerator of which is the number of days between your termination date and the first anniversary of the Effective Date, and the denominator of which is 365. 







 5. Benefits. You will be eligible to participate in the Company’s standard benefit
programs, which currently include holidays, 15 days of vacation, 5 days sick leave, medical insurance, dental insurance, 401(k) plan and life insurance, subject to the terms of such programs as in effect from time to time. 

6. Equity award. Subject to the approval of the Board, the Company will grant to you an option (the “Option”),
intended to qualify to the maximum extent permissible as an “incentive stock option” under Section 422 of the Internal Revenue Code of 1986, as amended (the “Code”), for the purchase of 339,124 shares of the
Company’s common stock with an exercise price per share equal to the per share fair market value, as determined by the Board, of the common stock on the date of grant. In all respects, the Option will be governed by the Seres Health, Inc. 2012
Stock Incentive Plan, as amended from time to time, and a stock option agreement to be entered into between you and the Company. 
 7.
Proprietary Information Agreement; Company policies. As a condition of this offer and your employment, you must sign and abide by the Company’s standard Employee Non-Competition, Non-Solicitation, Confidentiality and Assignment Agreement
(the “Proprietary Information Agreement”), a copy of which is enclosed and incorporated herein by reference. As a Company employee, you will be expected to abide by Company policies and procedures as may be in effect from time to
time. 
 8. At-will employment. It is understood that you are an “at-will” employee. You are not being offered employment
for a definite period of time, and either you or the Company may terminate the employment relationship at any time and for any reason without prior notice and without additional compensation to you, except as otherwise specifically provided in this
letter. 
 9. Termination benefits. In the event of the termination of your employment for any reason, the Company will pay you your
base salary plus any accrued but unused vacation through your last day of employment (the “Date of Termination”), and the amount of any documented, reimbursable expenses properly incurred by you on behalf of the Company prior to any
such termination and not yet reimbursed (collectively, the “Accrued Obligations”). In addition, if during the six (6) month period that immediately follows a Sale Event, the Company either (i) terminates your employment
without Cause or (ii) you resign from your employment for Good Reason (all as defined below) and provided you enter into within 52 days of the Date of Termination, do not revoke and comply with the terms of a separation agreement in a form
provided by the Company, which will include a general release of claims against the Company and related persons and entities, the Company will provide you with the following “Termination Benefits”: (a) continuation of your base
salary for the six (6) month period that immediately follows the Date of Termination (the “Salary Continuation Payments”); and (b) if elected, continuation of group health plan benefits to the extent authorized by and
consistent with COBRA, with the cost of the regular premium for such benefits shared in the same relative proportion by the Company and you as in effect on the Date Termination, until the earlier of (i) the date that is six (6) months
after the Date of Termination; and (ii) the date you become eligible for health benefits through another employer (and you agree to promptly notify the Company of such eligibility) or otherwise become ineligible for COBRA; and (c) any then
unvested portion of the Option shall become 

  
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fully vested upon the Date of Termination. The Salary Continuation Payments will commence within 60 days after the Date of Termination and shall be made on the Company’s regular payroll
dates; provided, however, that if the 60-day period begins in one calendar year and ends in a second calendar year, the Salary Continuation Payments shall begin to be paid in the second calendar year. In the event you miss a regular payroll period
between the Date of Termination and first Salary Continuation Payment date, the first Salary Continuation Payment will include a “catch up” payment. Solely for purposes of Section 409A of the Code, each Salary Continuation Payment is
considered a separate payment. For the avoidance of doubt, in the event your employment is terminated for any reason prior to a Sale Event, you will be entitled to the Accrued Obligations but you will not be entitled to Termination Benefits. 

10. Definitions. For the purposes of this letter: 

(a) “Cause” means: (i) conduct by you in connection with your service to the Company that is fraudulent, unlawful or
grossly negligent; (ii) your material breach of your material responsibilities to the Company or your willful failure to comply with lawful directives of the Board or written policies of the Company; (iii) breach by you of your
representations, warranties, covenants and/or obligations under this letter (including the Proprietary Information Agreement); and/or (iv) material misconduct by you which seriously discredits or damages the Company or any of its affiliates.

 (b) “Good Reason” means that you have complied with the “Good Reason Process” (hereinafter defined) following
the occurrence of any of the following actions undertaken by the Company without your express prior written consent: (i) the material diminution in your responsibilities, authority and function; or (ii) a material reduction in your base
salary; or (iii) a requirement by the Company that you relocate your principal location of employment to a location that is more than fifty (50) miles outside of the greater Boston metropolitan area. “Good Reason Process”
means that (i) you have reasonably determined in good faith that a Good Reason condition has occurred; (ii) you have notified the Company in writing of the first occurrence of the Good Reason condition within thirty (30) days of the
first occurrence of such condition; (iii) you have cooperated in good faith with the Company’s efforts, for a period not less than thirty (30) days following such notice (the “Cure Period”), to remedy the condition;
(iv) notwithstanding such efforts, the Good Reason condition continues to exist; and (v) you terminate your employment within thirty (30) days after the end of the Cure Period. If the Company cures the Good Reason condition during the
Cure Period, Good Reason shall be deemed not to have occurred. 
 (c) “Sale Event” means the consummation of (i) the
sale of all or substantially all of the assets of the Company on a consolidated basis to an unrelated person or entity, (ii) a merger, reorganization or consolidation involving the Company in which the shares of voting stock of the Company
outstanding immediately prior to such transaction represent or are converted into or exchanged for securities of the surviving or resulting entity immediately upon completion of such transaction which represent less than 50 percent of the
outstanding voting power of such surviving or resulting entity, (iii) the acquisition of all or a majority of the outstanding voting stock of the Company in a single transaction or a series of related transactions by a person, entity or group
of persons or entities, or (iv) any other 

  
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acquisition of the business of the Company, as determined by the Board; provided, however, that an initial public offering of the Company’s equity securities, any subsequent public offering
or another capital raising event, or a merger effected solely to change the Company’s domicile shall not constitute a “Sale Event.” 

11. Taxes; Section 409A. All forms of compensation referred to in this offer letter are subject to reduction to reflect applicable
withholding and payroll taxes and other deductions required by law. You hereby acknowledge that the Company does not have a duty to design its compensation policies in a manner that minimizes your tax liabilities, and you will not make any claim
against the Company or the Board related to tax liabilities arising from your compensation. Anything in this letter to the contrary notwithstanding, if at the time of your separation from service within the meaning of Section 409A of the Code,
the Company determines that you are a “specified employee” within the meaning of Section 409A(a)(2)(B)(i) of the Code, then to the extent any payment or benefit that you become entitled to under this letter on account of your
separation from service would be considered deferred compensation subject to the 20 percent additional tax imposed pursuant to Section 409A(a) of the Code as a result of the application of Section 409A(a)(2)(B)(i) of the Code, such payment
shall not be payable and such benefit shall not be provided until the date that is the earlier of (A) six months and one day after your separation from service, or (B) your death. If any such delayed cash payment is otherwise payable on an
installment basis, the first payment shall include a catch-up payment covering amounts that would otherwise have been paid during the six-month period but for the application of this provision, and the balance of the installments shall be payable in
accordance with their original schedule. To the extent that any payment or benefit described in this letter constitutes “non-qualified deferred compensation” under Section 409A of the Code, and to the extent that such payment or
benefit is payable upon your termination of employment, then such payments or benefits shall be payable only upon your separation from service. The determination of whether and when a separation from service has occurred shall be made in accordance
with the presumptions set forth in Treasury Regulation Section 1.409A-1(h). The Company and you intend that this letter will be administered in accordance with Section 409A of the Code. To the extent
that any provision of this letter is ambiguous as to its compliance with Section 409A of the Code, the provision shall be read in such a manner so that all payments hereunder comply with or are exempt from Section 409A of the Code. The
Company makes no representation or warranty and shall have no liability to you or any other person if any provisions of this letter are determined to constitute deferred compensation subject to Section 409A of the Code but do not satisfy an
exemption from, or the conditions of, such Section. 
 12. Entire agreement; governing law. This letter, along with the Proprietary
Information Agreement, sets forth the complete and exclusive agreement between you and the Company with regard to your employment with the Company, and supersedes any prior representations or agreements about this matter, whether written or verbal.
The terms of this letter and the resolution of any disputes as to the meaning, effect, performance or validity of this letter or arising out of, related to, or in any way connected with this letter, your employment with the Company or any other
relationship between you and the Company (the “Disputes”) will be governed by Massachusetts law, excluding laws relating to 

  
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conflicts or choice of law that would result in the application of law other than Massachusetts law. You and the Company submit to the exclusive personal jurisdiction of the federal and state
courts located in the Commonwealth of Massachusetts in connection with any Dispute or any claim related to any Dispute. 
 13.
Assignment. Neither you nor the Company may make any assignment of this letter or any interest in it, by operation of law or otherwise, without the prior written consent of the other; provided, however, that the Company may assign its rights
and obligations under this letter (including the Proprietary Information Agreement) without your consent to any affiliate or to any person or entity with whom the Company shall hereafter effect a reorganization, consolidate with, or merge into or to
whom it transfers all or substantially all of its properties or assets. This letter shall inure to the benefit of and be binding upon you and the Company, and each of your and its respective successors, executors, administrators, heirs and permitted
assigns. 
 14. Miscellaneous. This letter may not be modified or amended, and no breach shall be deemed to be waived, except by a
written agreement signed by you and an authorized officer of the Company. The headings and captions in this letter are for convenience only and in no way define or describe the scope or content of any provision of this letter. This letter may be
executed in two or more counterparts, each of which shall be an original and all of which together shall constitute one and the same instrument. 

15. Other terms. This offer is subject to background and reference checks that are satisfactory to the Company. In making this offer,
the Company understands, and in accepting it you represent that you are not under any obligation to any former employer or any person, firm, or corporation which would prevent, limit, or impair in any way the performance by you of your duties as an
employee of the Company. The Immigration Reform and Control Act requires employers to verify the employment eligibility and identity of new employees. Enclosed is a copy of the Form I-9 that you will be
required to complete. Please bring the appropriate documents listed on that form with you when you report for work. We will not be able to employ you if you fail to comply with this requirement. 

Please indicate your acceptance of this offer by returning signed and dated copies of this letter and the Proprietary Information Agreement to Eric Shaff at
eshaff@sereshealth.com no later than Tuesday, December 23, 2014, after which date this offer will expire. 
 We look forward to your joining the
Company and are very pleased that you will be working with us. 
  

	
	Very truly yours,
	
	 /s/ Roger Pomerantz

	
	 Roger Pomerantz
 President and CEO

SERES HEALTH, INC.



  
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 Accepted and Agreed: 
  

	
	 /s/ Michele Trucksis

	Michele Trucksis
	
	 12/23/2014

	Date:


  
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