Exhibit
10.16





Institute
of Microbiology, Chinese Academy of Sciences


Laiyang
Jiangbo Pharmaceutical Co. Ltd


Pharmaceutical
Industrialization Joint Base Agreement





Party A:
Institute of Microbiology, Chinese Academy of Sciences (IMCAS)


Party B:
Laiyang Jiangbo Pharmaceutical Co, .Ltd.





Under the
background of National "Eleventh Five-Year Plan" program, IMCAS actively
promotes the industrialization of scientific research to utilize its own
advantages adequately and implements the policy of IMCAS and the knowledge
innovation project. With the foundation of continuous improved yearly production
value and revenues, Laiyang Jiangbo Pharmaceutical Co. Ltd. focuses on
strengthening the basic research of biomedical industrial in order to achieve a
new level. Therefore, both parties reached the agreement to form the “Joint
base of industrialization, Institute of Microbiology, Chinese Academy of
Sciences-Laiyang Jiangbo Pharmaceutical Co. Ltd” with the formation of good
cooperative research system in order to promote the further development of bio-
pharmaceutical industry with the approach of joining enterprise and institute.
This agreement is signed for the implementation of this
cooperation.





A.
            Name
      of the Joint base of
industrialization


Joint
base of industrialization, Institute of Microbiology, Chinese Academy of
Sciences – Laiyang Jiangbo Pharmaceutical Co, Ltd





B.
            Operation
      model of the Joint base of
industrialization


1.
            Joint
      base of industrialization will be licensed and operated at Party
      B.


2.
            Party
      A and Party B should both assign a representative to take responsibility
      for the work of joint base of industrialization. Both of Party A and Party
      B can recruit related employees in accordance with
      requirement.


3.
            The
      joint base should hold at least one working conference or academic
      exchange every year and both parties’ research and managerial personnel
      should participate the conference or academic
  exchange.





C.
            Responsibilities
      of both Party


1.
            Party
      A.


a.
            Give
      Party B the priority to get the transferable technological
      achievements.


b.
            Cultivate
      post-doctoral or master and doctoral students and training related
      technical staff for Party B. Related expenses will be negotiated by both
      parties.


c.
            Within
      the scientific research scope of IMCAS, Party A will solve the problems
      encountered in Party B’s production process for Party B; specific issues
      will be resolved by other agreements between the two
    parties.









d.
            Both
      parties should apply for national and local projects (such as 863 projects
      etc). Party A shall provide party B technical
  support.





2.
            Party
      B.


a.
Provide party A related industrial technological achievements transformation
platform.


b.
Provide RMB 6,000,000 per year operating expenses for the Joint base of
industrialization.


c. Bear
enterprise related responsibilities during the application process of national
and local projects.





D.
            Cooperation
      period


The
agreement is for five years (November 2006 till November 2010). Both
parties will renegotiate the terms after the contract expires.





E.
              Others


1.
            Matters
      not mentioned herein and other possible disputes occurred during the
      operation process of the cooperative library shall be decided through
      mutual negotiations.


2.
            This
      agreement shall be validated with the representatives from both
      parties’ signatures and seals. This agreement has four copies, two
      copies for both sides with same legal
effect.





Party A
(Representative): (Seal)


Institute
of Microbiology, Chinese Academy of Sciences


November
12, 2007




Party B
(Representative): (Seal)


Laiyang
Jiangbo Pharmaceutical Co. Ltd.


November
12, 2007