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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 10-Q

(Mark One)

|x | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
|- | ---------------------------------------------------------------------------------------

For the quarterly period ended March 31, 2010

or



| ̈ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
|- | ----------------------------------------------------------------------------------------

For the transition period from  to

Commission File
Number 001-10109

BECKMAN COULTER, INC.

(Exact name of registrant as specified in its charter)



|                                                               |  |                                     
|-------------------------------------------------------------- |  | ------------------------------------
|Delaware                                                       |  | 95-104-0600                         
|(State or other jurisdiction of
incorporation or organization) |  | (I.R.S. Employer Identification No.)



|                                           |  |           
|------------------------------------------ |  | ----------
|250 S. Kraemer Boulevard,
Brea, California |  | 92821     
|(Address of principal executive offices)   |  | (Zip Code)

(714)
993-5321

(Registrants telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the
Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90
days.    Yes  x    No   ̈

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every
Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 229.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such
files).    Yes   ̈    No   ̈

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller
reporting company. See the definitions of large accelerated filer, accelerated filer and smaller reporting company in Rule 12b-2 of the Exchange Act.



|                           |  |                                               |  |                             
|-------------------------- |  | --------------------------------------------- |  | ----------------------------
|Large accelerated filer  x |  |                                               |  | Accelerated filer   ̈        
|                           |  |                                              
|Non-accelerated filer   ̈   |  | (Do not check if a smaller reporting company) |  | Smaller reporting company   ̈

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange
Act).    Yes   ̈    No  x.

The number of outstanding shares of the registrants common stock as of April 23, 2010 was 70,102,511 shares.









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##### Table of Contents

TABLE OF CONTENTS



|                             |  |                                                                                       |  |   
|---------------------------- |  | ------------------------------------------------------------------------------------- |  | --
|Part IFinancial Information |  |                                                                                      
|Item 1.                      |  | Financial Statements                                                                  |  | 3 
|                             |  | Condensed Consolidated Balance Sheets                                                 |  | 3 
|                             |  | Condensed Consolidated Statements of Earnings                                         |  | 4 
|                             |  | Condensed Consolidated Statements of Cash Flows                                       |  | 5 
|                             |  | Notes to Condensed Consolidated Financial Statements                                  |  | 6 
|Item 2.                      |  | Managements Discussion and Analysis of Financial Condition and Results of Operations |  | 17
|Item 3.                      |  | Quantitative and Qualitative Disclosures About Market Risk                            |  | 30
|Item 4.                      |  | Controls and Procedures                                                               |  | 31
|                             | 
|Part IIOther Information    |  |                                                                                      
|Item 1A.                     |  | Risk Factors                                                                          |  | 31
|Item 2.                      |  | Unregistered Sales of Equity Securities and Use of Proceeds                           |  | 37
|Item 6.                      |  | Exhibits                                                                              |  | 37
|Signatures                   |  | 38                                                                                   



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##### Table of Contents

PART IFINANCIAL INFORMATION



|Item 1. | Financial Statements
|------- | --------------------

Condensed Consolidated Balance Sheets

(in millions, except amounts per share)

(unaudited)



|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ------------- | ------- | -------------------- | - | -------
|                                                                                                                                                                                                                                  |  | March 31,2010 |         | December 31,    2009
|Assets                                                                                                                                                                                                                            |  |               |         |                      |   |        
|Current assets                                                                                                                                                                                                                    |  |               |         |                      |   |        
|Cash and cash equivalents                                                                                                                                                                                                         |  | $             | 296.5   |                      | $ | 288.8  
|Trade and other receivables, net                                                                                                                                                                                                  |  |               | 809.2   |                      |   | 827.9  
|Inventories                                                                                                                                                                                                                       |  |               | 596.4   |                      |   | 596.8  
|Deferred income taxes                                                                                                                                                                                                             |  |               | 65.7    |                      |   | 79.0   
|Prepaids and other current assets                                                                                                                                                                                                 |  |               | 109.1   |                      |   | 77.4   
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Total current assets                                                                                                                                                                                                              |  |               | 1,876.9 |                      |   | 1,869.9
|Property, plant and equipment, net                                                                                                                                                                                                |  |               | 617.7   |                      |   | 621.9  
|Customer leased instruments, net                                                                                                                                                                                                  |  |               | 503.5   |                      |   | 523.0  
|Goodwill                                                                                                                                                                                                                          |  |               | 1,042.0 |                      |   | 1,041.9
|Other intangible assets, net                                                                                                                                                                                                      |  |               | 547.7   |                      |   | 561.8  
|Other assets                                                                                                                                                                                                                      |  |               | 64.2    |                      |   | 58.6   
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Total assets                                                                                                                                                                                                                      |  | $             | 4,652.0 |                      | $ | 4,677.1
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Liabilities and Stockholders Equity                                                                                                                                                                                              |  |               |         |                      |   |        
|Current liabilities                                                                                                                                                                                                               |  |               |         |                      |   |        
|Accounts payable                                                                                                                                                                                                                  |  | $             | 263.1   |                      | $ | 235.7  
|Accrued expenses                                                                                                                                                                                                                  |  |               | 498.2   |                      |   | 540.1  
|Income taxes payable                                                                                                                                                                                                              |  |               | 0.9     |                      |   | 5.6    
|Short-term borrowings                                                                                                                                                                                                             |  |               | 5.1     |                      |   | 1.8    
|Current maturities of long-term debt                                                                                                                                                                                              |  |               | 24.6    |                      |   | 24.1   
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Total current liabilities                                                                                                                                                                                                         |  |               | 791.9   |                      |   | 807.3  
|Long-term debt, less current maturities                                                                                                                                                                                           |  |               | 1,309.3 |                      |   | 1,305.9
|Deferred income taxes                                                                                                                                                                                                             |  |               | 49.1    |                      |   | 50.1   
|Other liabilities                                                                                                                                                                                                                 |  |               | 520.0   |                      |   | 552.6  
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Total liabilities                                                                                                                                                                                                                 |  |               | 2,670.3 |                      |   | 2,715.9
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Commitments and contingencies (see Note 13)                                                                                                                                                                                       |  |               |         |                      |   |        
|Stockholders equity                                                                                                                                                                                                              |  |               |         |                      |   |        
|Preferred stock, $0.10 par value; authorized 10.0 shares; none issued                                                                                                                                                             |  |               | -       |                      |   | -      
|Common stock, $0.10 par value; authorized 300.0 shares; shares issued 73.9 and 73.8 at March 31, 2010 and December 31,
2009, respectively; shares outstanding 70.1 and 69.6 at March 31, 2010 and December 31, 2009, respectively |  |               | 7.4     |                      |   | 7.4    
|Additional paid-in capital                                                                                                                                                                                                        |  |               | 885.8   |                      |   | 886.8  
|Retained earnings                                                                                                                                                                                                                 |  |               | 1,508.6 |                      |   | 1,482.7
|Accumulated other comprehensive loss                                                                                                                                                                                              |  |               | (196.4) |                      |   | (176.8)
|Treasury stock, at cost: 3.4 and 3.8 common shares at March 31, 2010 and December 31, 2009,
respectively                                                                                                                          |  |               | (223.7) |                      |   | (238.9)
|Common stock held in grantor trust, at cost: 0.4 common shares at March 31, 2010 and December 31, 2009                                                                                                                            |  |               | (22.3)  |                      |   | (21.3) 
|Grantor trust liability                                                                                                                                                                                                           |  |               | 22.3    |                      |   | 21.3   
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Total stockholders equity                                                                                                                                                                                                        |  |               | 1,981.7 |                      |   | 1,961.2
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        
|Total liabilities and stockholders equity                                                                                                                                                                                        |  | $             | 4,652.0 |                      | $ | 4,677.1
|                                                                                                                                                                                                                                  |  |               |         |                      |   |        

See accompanying Notes to Condensed Consolidated
Financial Statements.



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Condensed Consolidated Statements of Earnings

(in millions, except amounts per share)

(unaudited)



|                                                             |  |                        |        |      |   |       
|------------------------------------------------------------ |  | ---------------------- | ------ | ---- | - | ------
|                                                             |  | Quarter EndedMarch 31,
|                                                             |  | 2010                   |        | 2009
|Recurring revenue  supplies, service and lease payments     |  | $                      | 731.3  |      | $ | 573.7 
|Instrument sales                                             |  |                        | 149.8  |      |   | 117.8 
|                                                             |  |                        |        |      |   |       
|Total revenue                                                |  |                        | 881.1  |      |   | 691.5 
|                                                             |  |                        |        |      |   |       
|Cost of recurring revenue                                    |  |                        | 354.5  |      |   | 268.3 
|Cost of instrument sales                                     |  |                        | 121.6  |      |   | 104.1 
|                                                             |  |                        |        |      |   |       
|Total cost of sales                                          |  |                        | 476.1  |      |   | 372.4 
|                                                             |  |                        |        |      |   |       
|Operating costs and expenses                                 |  |                        |        |      |   |       
|Selling, general and administrative                          |  |                        | 222.9  |      |   | 185.9 
|Research and development                                     |  |                        | 70.1   |      |   | 59.9  
|Amortization of intangible assets                            |  |                        | 13.9   |      |   | 7.3   
|Restructuring and acquisition related costs                  |  |                        | 18.2   |      |   | 26.4  
|                                                             |  |                        |        |      |   |       
|Total operating costs and expenses                           |  |                        | 325.1  |      |   | 279.5 
|                                                             |  |                        |        |      |   |       
|Operating income                                             |  |                        | 79.9   |      |   | 39.6  
|                                                             |  |                        |        |      |   |       
|Non-operating (income) expense                               |  |                        |        |      |   |       
|Interest income                                              |  |                        | (1.3)  |      |   | (1.3) 
|Interest expense                                             |  |                        | 24.1   |      |   | 10.9  
|Other, net                                                   |  |                        | (0.3)  |      |   | 11.8  
|                                                             |  |                        |        |      |   |       
|Total non-operating expense                                  |  |                        | 22.5   |      |   | 21.4  
|                                                             |  |                        |        |      |   |       
|Earnings before income taxes                                 |  |                        | 57.4   |      |   | 18.2  
|Income tax provision (benefit)                               |  |                        | 18.7   |      |   | (2.4) 
|                                                             |  |                        |        |      |   |       
|Net earnings                                                 |  | $                      | 38.7   |      | $ | 20.6  
|                                                             |  |                        |        |      |   |       
|Basic earnings per share                                     |  | $                      | 0.55   |      | $ | 0.32  
|                                                             |  |                        |        |      |   |       
|Diluted earnings per share                                   |  | $                      | 0.54   |      | $ | 0.32  
|                                                             |  |                        |        |      |   |       
|Weighted average number of shares outstanding (in thousands) |  |                        |        |      |   |       
|Basic                                                        |  |                        | 70,321 |      |   | 63,545
|Diluted                                                      |  |                        | 71,534 |      |   | 64,122

See
accompanying Notes to Condensed Consolidated Financial Statements.



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Condensed Consolidated Statements of Cash Flows

(in millions)

(unaudited)



|                                                                                                   |  |                        |        |      |   |       
|-------------------------------------------------------------------------------------------------- |  | ---------------------- | ------ | ---- | - | ------
|                                                                                                   |  | Quarter EndedMarch 31,
|                                                                                                   |  | 2010                   |        | 2009
|Cash flows from operating activities                                                               |  |                        |        |      |   |       
|Net earnings                                                                                       |  | $                      | 38.7   |      | $ | 20.6  
|Adjustments to reconcile net earnings from operations to net cash provided by operating activities |  |                        |        |      |   |       
|Depreciation and amortization                                                                      |  |                        | 89.1   |      |   | 67.5  
|Provision for doubtful accounts receivable                                                         |  |                        | 1.6    |      |   | 0.4   
|Share-based compensation expense                                                                   |  |                        | 10.3   |      |   | 11.3  
|U.S. pension trust contributions                                                                   |  |                        | (20.0) |      |   | -     
|Accreted interest on convertible debt                                                              |  |                        | 3.7    |      |   | 3.5   
|Amortization of pension and postretirement costs                                                   |  |                        | 4.8    |      |   | 4.0   
|Deferred income taxes                                                                              |  |                        | 16.8   |      |   | (9.8) 
|Changes in assets and liabilities, net of acquisitions                                             |  |                        |        |      |   |       
|Trade and other receivables                                                                        |  |                        | 2.5    |      |   | 33.7  
|Prepaid and other current assets                                                                   |  |                        | (16.6) |      |   | (1.9) 
|Inventories                                                                                        |  |                        | (12.9) |      |   | (41.6)
|Accounts payable and accrued expenses                                                              |  |                        | (2.8)  |      |   | 8.8   
|Income taxes payable                                                                               |  |                        | (5.4)  |      |   | 9.7   
|Long-term lease receivables                                                                        |  |                        | (0.5)  |      |   | 4.3   
|Other                                                                                              |  |                        | (11.1) |      |   | (4.8) 
|                                                                                                   |  |                        |        |      |   |       
|Net cash provided by operating activities                                                          |  |                        | 98.2   |      |   | 105.7 
|                                                                                                   |  |                        |        |      |   |       
|Cash flows from investing activities                                                               |  |                        |        |      |   |       
|Additions to property, plant and equipment                                                         |  |                        | (34.3) |      |   | (30.9)
|Additions to customer leased instruments                                                           |  |                        | (36.9) |      |   | (29.6)
|Purchase of investments                                                                            |  |                        | (15.1) |      |   | -     
|Payments for technology licenses                                                                   |  |                        | (2.5)  |      |   | -     
|                                                                                                   |  |                        |        |      |   |       
|Net cash used in investing activities                                                              |  |                        | (88.8) |      |   | (60.5)
|                                                                                                   |  |                        |        |      |   |       
|                                                                                                   |  |                       
|Cash flows from financing activities                                                               |  |                        |        |      |   |       
|Dividends to stockholders                                                                          |  |                        | (12.9) |      |   | (10.8)
|Proceeds from issuance of common stock                                                             |  |                        | 25.0   |      |   | 11.1  
|Repurchase of common stock as treasury stock                                                       |  |                        | (14.8) |      |   | -     
|Repurchase of common stock held in grantor trust                                                   |  |                        | -      |      |   | (1.3) 
|Excess tax benefits from share-based payment transactions                                          |  |                        | 2.2    |      |   | 0.6   
|Net borrowings (payments) on lines of credit                                                       |  |                        | 3.6    |      |   | (6.9) 
|                                                                                                   |  |                        |        |      |   |       
|Net cash provided by (used in) financing activities                                                |  |                        | 3.1    |      |   | (7.3) 
|                                                                                                   |  |                        |        |      |   |       
|Effect of exchange rates on cash and cash equivalents                                              |  |                        | (4.8)  |      |   | (10.2)
|Change in cash and cash equivalents                                                                |  |                        | 7.7    |      |   | 27.7  
|Cash and cash equivalents-beginning of period                                                      |  |                        | 288.8  |      |   | 120.0 
|                                                                                                   |  |                        |        |      |   |       
|Cash and cash equivalents-end of period                                                            |  | $                      | 296.5  |      | $ | 147.7 
|                                                                                                   |  |                        |        |      |   |       

See accompanying Notes to Condensed Consolidated
Financial Statements.



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Notes to Condensed Consolidated Financial Statements

(tabular dollar amounts in millions, except amounts per share)

(unaudited)

Note 1.  Nature of Business and Summary of Significant Accounting Policies

Nature of Business

Beckman Coulter, Inc. (Beckman Coulter, the Company, we, our) is a leading manufacturer of
biomedical testing instrument systems, tests and supplies that simplify and automate laboratory processes. Spanning the biomedical testing continuumfrom pioneering medical research and clinical trials to laboratory diagnostics and
point-of-care testingour installed base of systems provides essential biomedical information to enhance health care around the world. We are dedicated to improving patient health and reducing the cost of care.

Our revenue is about evenly distributed inside and outside of the United States (U.S.). Clinical Diagnostics sales
represented approximately 86% of our total revenue in 2009, with the balance coming from the Life Science markets. Approximately 81% of our total revenue in 2009 was generated by recurring revenue from consumable supplies (including reagent test
kits), services and operating type lease (OTL) payments. Central laboratories of mid-to large-size hospitals represent our most significant customer group.

Basis of Presentation

We prepared the accompanying Condensed Consolidated Financial Statements following the requirements of the United States Securities and
Exchange Commission for interim reporting. As permitted under those rules, certain footnotes or other financial information normally required by generally accepted accounting principles in the United States of America (U.S. GAAP) have
been condensed or omitted.

Our financial statements include all normal and recurring adjustments that we consider necessary
for the fair presentation of our financial position and operating results. These Condensed Consolidated Financial Statements should be read in conjunction with the Consolidated Financial Statements and notes in our Annual Report on Form 10-K for the
year ended December 31, 2009.

Revenue, expenses, assets and liabilities can vary between the quarters and our results of
operations for the quarter ended March 31, 2010 do not necessarily indicate our operating results to be expected for the full year or any future period.

Use of Estimates

We
follow U.S. GAAP, which requires us to make estimates and assumptions about future events. These estimates and the underlying assumptions affect the reported amounts of assets, liabilities, revenue and expenses, and disclosures about contingent
assets and liabilities. Such estimates include the valuation of accounts receivable, inventories, long-lived assets, lives of customer leased instruments, lives of plant and equipment, lives of intangible assets, and assumptions used in the
calculation of warranty accruals, employee benefit plan obligations, environmental and litigation obligations, legal contingencies, income taxes, share-based compensation and others. These estimates and assumptions are based on managements
best estimates and judgment and affect the amounts reported in the consolidated financial statements and accompanying notes. Actual results could differ from those estimates. Management evaluates its estimates and assumptions on an ongoing basis
using historical experience and other factors, including the current economic environment, which management believes to be reasonable under the circumstances. As future events and their effects cannot be determined with precision, actual results
could differ significantly from these estimates. Changes in those estimates will be reflected in the financial statements in future periods.

Income Taxes

At the end
of each interim reporting period, an estimate is made of the effective tax rate expected to apply to the full year. The estimated annual effective tax rate is used to determine the income tax rate for each applicable interim reporting period. The
tax effect of any tax law changes, final settlement of examinations with tax authorities and certain other events are reflected as discrete items in the interim reporting period in which they occur.

The effective tax rate for the quarter ended March 31, 2010 was 32.6% and was impacted by discrete events which increased tax
expense for the quarter by a net $3.6 million. Discrete events arising in the first quarter of 2010 that reduced tax expense by $5.1 million, related to various adjustments to prior year tax credits, the effects of statutes of limitations expiring
in various countries, and a settlement of an international tax audit. These were offset by discrete events which increased tax expense by $8.7 million, of which $0.7 million relates to adjustments to prior year tax returns and $8.0 million relates
to a reduction in a deferred tax asset related to



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Medicare drug subsidies resulting from tax law changes enacted in the United States in the first quarter as part of the Patient Protection and Affordable Care Act and the Health Care and
Education Reconciliation Act of 2010.

The Company and its domestic subsidiaries file federal, state and local
income/franchise tax returns in the U.S. Our international subsidiaries file income tax returns in various non-U.S. jurisdictions. Tax years 2006 through 2008 are currently subject to a U.S. federal income tax examination by the Internal Revenue
Service (IRS). The earliest tax years of our major international subsidiaries that are subject to non-U.S. income tax examinations by tax authorities are: Switzerland, 1998; Hong Kong, 2002; Italy and Canada, 2005; Germany, 2006; France
and the United Kingdom, 2007; and Japan, 2008.

During the first quarter of 2009, we filed certain tax accounting method
changes with the IRS. As a result of these accounting method changes, certain tax deductions were accelerated and reflected in the 2008 federal income tax return, resulting in a net operating loss for that year. This loss has been carried back to
the 2006 tax year, which reduced taxes previously paid by $66.0 million. The acceleration of these tax deductions reduced certain permanent tax benefits totaling $3.4 million which increased tax expense in 2009.

We accrue interest and penalties where there is underpayment of taxes, based on managements best estimate of the amount ultimately
to be paid, in the same period that the interest would begin accruing or the penalties would first be assessed. We recognize interest and penalties as part of interest expense. At March 31, 2010, we had $2.1 million in accrued interest and
penalties for income taxes. During the first three months of 2010, we reversed $0.3 million of interest and penalties primarily as a result of the settlement of tax audits and expiration of various statutes of limitation in certain countries.

The total amount of unrecognized tax benefits as of March 31, 2010 was $31.8 million, which if recognized, would affect
our effective tax rate in future periods.

A number of years may elapse before an uncertain tax position is finally resolved.
It is difficult to predict the final outcome or the timing of resolution of any particular uncertain tax position. We reevaluate and adjust our reserves for income taxes, as well as the related interest, in light of changing facts and circumstances.
Settlement of any particular position would usually require the use of cash and result in the reduction of the related reserve. The resolution of a matter would be recognized as an adjustment to the provision for income taxes and effective tax rate
in the period of resolution. It is reasonably possible that our liability for uncertain tax positions could be reduced by as much as $5.7 million over the next 12 months as a result of the settlement of tax positions with various tax authorities.

Recently Adopted Accounting Standards

Accounting for Transfers of Financial Assets

In June 2009, the FASB issued an accounting standard for transfers and servicing of financial assets. This guidance removes the
concept of a qualifying special-purpose entity from the accounting standard for transfers and servicing and removes the exception from applying Consolidation of Variable Interest Entities from the accounting standard for
consolidation. This guidance also clarifies the requirements for isolation and limitations on portions of financial assets that are eligible for sale accounting. We adopted this standard as of January 1, 2010, which did not materially impact
our consolidated financial position, results of operations and cash flows.

Revenue Arrangements with Multiple Deliverables

In October 2009, the FASB issued an update to the accounting standard for revenue recognition related to multiple-element
arrangements, which in certain instances requires companies to allocate revenue in arrangements involving multiple deliverables based on the estimated selling price of each deliverable, even though such deliverables are not sold separately either by
the company itself or other vendors. This standard eliminates the requirement that all undelivered elements must have objective and reliable evidence of fair value before a company can recognize the portion of the overall arrangement fee that is
attributable to items that already have been delivered. As a result, the new guidance may allow some companies to recognize revenue on transactions that involve multiple deliverables earlier than under previous requirements. This standard is
required to be adopted in the first quarter of fiscal year 2011; however, early adoption is permitted. We elected to adopt this standard on a prospective basis as of January 1, 2010. The adoption of this standard did not cause any changes to
the amount of revenue recognized or the presentation of amounts within our consolidated financial position, results of operations and cash flows. Under this standard, fair value as the measurement criteria is replaced with the term selling price and
establishes a hierarchy for determining the selling price of a deliverable. Also, the use of the residual value method for determining the allocation of arrangement consideration is eliminated. Neither the implementation of the use of estimated
selling price nor the elimination of the residual method caused any changes to our revenue recognition polices. For our sales type lease and sale agreements that include multiple deliverables, such as installation, training, after-market supplies or



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service, we allocate revenue to all deliverables based on their relative selling prices. We use a hierarchy to determine the selling price to be used for allocating revenue to deliverables as
follows: (i) vendor-specific objective evidence of fair value (VSOE), (ii) third-party evidence of selling price (TPE), and (iii) best estimate of the selling price (ESP). VSOE generally exists only
when we sell the deliverable separately and is the price actually charged for that deliverable. Our process for determining an ESP for deliverables without VSOE or TPE considers multiple factors that may vary depending upon the unique facts and
circumstances related to each deliverable.

The vast majority of our revenue is generated from consumable supplies, service,
and OTL payment arrangements. When a customer enters into an OTL agreement, instrument lease revenue is recognized on a straight-line basis over the life of the lease. Under an STL agreement, the instrument sales revenue and related cost is
generally recognized at the time of customer shipment based on the present value of the minimum lease payments with interest income recognized over the life of the lease using the interest method. Supplies and test kit revenue is generally
recognized at the time of delivery or usage. Service revenue on maintenance contracts is recognized ratably over the life of the service agreement or as service is performed, if not under the contract.

Certain Revenue Arrangements That Include Software Elements

In October 2009, the FASB issued an update to the accounting standard for software revenue recognition. This standard reduces the types of
transactions that fall within the current scope of software revenue recognition guidance. Existing software revenue recognition guidance requires that its provisions be applied to an arrangement when the sale of any products or services containing
or utilizing software when the software is considered more than incidental to the product or service. As a result of the update to the accounting standard, many tangible products that rely on software will not be accounted for under the software
revenue recognition guidance. Under this update, the following components would be excluded from the scope of software revenue recognition guidance: the tangible element of the product, software products bundled with tangible products where the
software components and non-software components function together to deliver the products essential functionality, and undelivered components that relate to software that is essential to the tangible products functionality. The amendment
also provides guidance on how to allocate transaction consideration when an arrangement contains both deliverables within the scope of software revenue guidance (software deliverables) and deliverables not within the scope of that guidance
(non-software deliverables). We must elect the same transition method for this guidance as that chosen for by the accounting standard update for revenue recognition related to multiple-element arrangements discussed above. Therefore, we adopted this
standard as well on a prospective basis as of January 1, 2010. The adoption of this standard did on not have an impact our consolidated financial position, results of operations and cash flows.



|Note 2.  Acquisitions | 
|--------------------- | 

Olympus Diagnostics Systems
Business

On August 3, 2009, we completed the acquisition of the laboratory-based diagnostics systems business of
Olympus Corporation (referred to as Olympus) through a cash payment of approximately 76 billion Japanese yen (approximately U.S. $800 million based on currency exchange rates as of August 3, 2009). Based on an estimate of the final closing net
assets, an additional $17.5 million and $3.5 million was recorded as a liability for additional purchase price with a corresponding increase in goodwill during December 2009 and March 2010, respectively.



|Note 3.  Restructuring | Activities, Acquisition Related Costs, and Asset Impairment Charges
|---------------------- | -------------------------------------------------------------------

Restructuring Activities

Restructuring actions and exit activities generally include significant actions involving employee-related severance charges, contract
termination costs, and impairment of assets associated with such actions.

Employee-related severance charges are largely
based upon distributed employment policies and substantive severance plans and are reflected in the quarter in which management approves the associated actions and the amount of the severance is probable and estimable. Severance amounts for which
affected employees were required to render service in order to receive benefits at their termination dates were measured at the date such benefits were communicated to the applicable employees and recognized as expense over the employees
remaining service periods.

Contract termination and other charges primarily reflect costs to terminate a contract before the
end of its term (measured at fair value at the time the Company provided notice to the counterparty) or costs that will continue to be incurred under the contract for its remaining term without economic benefit to the Company. Asset impairment
charges related to property, plant and equipment reflect the excess of the assets carrying values over their fair values.



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Total Restructuring Charges

During the first quarter of 2010 and 2009, we recorded restructuring charges of $6.6 million and $16.6 million, respectively. These
charges related to severance, relocation, asset impairment and other exit costs were included within the restructuring and acquisition related costs line of our Condensed Consolidated Statement of Earnings. From January 2007 through the first
quarter of 2010, we incurred a total of $134.0 million of net restructuring charges of which $50.9 million relates to severance costs.

Following is a detailed description of charges included in restructuring activities:

Supply Chain Initiatives

During the first quarter of 2009, as part of our supply chain initiatives, we announced the closure and relocation of certain
manufacturing and distribution sites. Additionally, during 2008, we announced our intent to vacate our Fullerton, California facility and consolidate those operations to other existing facilities (Orange County consolidation project). As
part of these relocations, during the quarters ended March 31, 2010 and 2009, we incurred severance and other relocation charges of $1.5 million and $16.0 million, respectively.

Clinical Diagnostics Business

In connection with the Olympus acquisition, we incurred severance costs during the quarter ended March 31, 2010, of $2.2 million due
to redundancies as part of combining the two entities.

Asset Impairment Charges and Employee Severance

During the quarter ended March 31, 2010 and March 31, 2009, we incurred asset impairment charges of $2.9 million and $0.6
million associated with our consolidation effort to close and relocate other facilities and relocate operations.

The
following is a reconciliation of the accrual for employee severance and other related costs included in accrued expenses in the Condensed Consolidated Balance Sheet at March 31, 2010:



|                             |  |   |       
|---------------------------- |  | - | ------
|Balance at December 31, 2009 |  | $ | 41.9  
|Additional charges           |  |   | 6.6   
|Utilization                  |  |   | (10.1)
|                             |  |   |       
|Balance at March 31, 2010    |  | $ | 38.4  
|                             |  |   |       

Acquisition Related Costs

In connection with the Olympus and Cogenics acquisitions, we incurred acquisition related and integration costs of $11.6 million and $9.8
million during the quarters ended March 31, 2010 and 2009, respectively. These charges are included within the restructuring and acquisition related costs line of our Condensed Consolidated Statement of Earnings.



|Note 4.  Derivatives | 
|-------------------- | 

We use derivative
financial instruments to hedge foreign currency exposures. Our objectives for holding derivatives are to minimize currency risks using the most effective methods to eliminate or reduce the impacts of these exposures. We do not speculate in
derivative instruments to profit from foreign currency exchange fluctuations nor do we enter into trades for which there are no underlying exposures. We have minimal exposure to interest rate fluctuations. The following discusses in more detail our
foreign currency exposures and related derivative instruments.

Foreign Currency

We manufacture approximately 75% of our products in the U.S., but generated approximately 54% of our revenue during the first quarter of
2010 from sales made outside the U.S. by our international subsidiaries. Revenues generated by our international subsidiaries generally are denominated in the subsidiarys local currency, thereby exposing us to the risk of foreign currency
fluctuations. To mitigate the impact of changes in foreign currency exchange rates, we use derivative financial instruments (or foreign currency contracts) to hedge the foreign currency exposure resulting from intercompany cash flows
associated with intercompany inventory purchases by our international subsidiaries through their anticipated cash settlement date. These foreign currency contracts include forward and option contracts and are designated as cash flow hedges. The
major currencies against which we hedge are the Euro, Japanese yen, Australian dollar, British Pound Sterling and Canadian dollar. As of March 31, 2010 and December 31, 2009, the notional amounts of all derivative foreign exchange
contracts were $517.3 million and $546.3 million, respectively.



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Hedge ineffectiveness associated with our cash flow hedges was immaterial and no cash flow
hedges were discontinued in the quarters ended March 31, 2010 and 2009. Derivative gains and losses on effective hedges included in accumulated other comprehensive loss are reclassified into cost of sales upon the recognition of the hedged
transaction. We estimate that substantially all of the $0.2 million of unrealized gain included in accumulated other comprehensive loss at March 31, 2010 will be reclassified to cost of sales within the next twelve months. The actual amounts
that will be reclassified to earnings over the next twelve months will vary from this amount as a result of changes in market rates. We have cash flow hedges at March 31, 2010, which settle as late as July 2011.

We also use foreign currency forward contracts to offset the effect of changes in value of loans between subsidiaries and do not
designate these derivative instruments as accounting hedges, therefore the changes in the value of these derivative instruments are included within the non-operating (income) expense section of the Consolidated Statement of Earnings.

The following table presents the fair value of derivative instruments within the Condensed Consolidated Balance Sheet:



|                                                    |  |                       |               |                   |                  |                      |   |                       |  |                            |  |   |     |  |   |    
|--------------------------------------------------- |  | --------------------- | ------------- | ----------------- | ---------------- | -------------------- | - | --------------------- |  | -------------------------- |  | - | --- |  | - | ---
|                                                    |  | BalanceSheetLocation  |               | Asset Derivatives |                  | BalanceSheetLocation |   | Liability Derivatives
|                                                    |  |                       | March 31,2010 |                   | December 31,2009 |                      |   | March 31,2010         |  | December 
31,2009         
|Derivatives designated as hedging instruments       |  |                       |               |                   |                  |                      |   |                       |  |                            |  |   |     |  |   |    
|Foreign exchange forwards and options               |  | Other currentassets   |               | $                 | 10.6             |                      | $ | 7.6                   |  | Other currentliabilities   |  | $ | 3.3 |  | $ | 5.6
|                                                    |  |                       |               |                   |                  |                      |   |                       |  |                            |  |   |     |  |   |    
|Foreign exchange forwards                           |  | Other long termassets |               |                   | 2.5              |                      |   | -                     |  | Other longterm liabilities |  |   | 1.1 |  |   | -  
|                                                    |  |                       |               |                   |                  |                      |   |                       |  |                            |  |   |     |  |   |    
|Total derivatives designated as hedging instruments |  |                       |               | $                 | 13.1             |                      | $ | 7.6                   |  |                            |  | $ | 4.4 |  | $ | 5.6
|                                                    |  |                       |               |                   |                  |                      |   |                       |  |                            |  |   |     |  |   |    

The following tables present the amounts affecting the
consolidated financial statements:



|                                               |  |                                                                           |     |                                                                                          |   |                                                                                             |  |               |  |      |       |  |   |    
|---------------------------------------------- |  | ------------------------------------------------------------------------- | --- | ---------------------------------------------------------------------------------------- | - | ------------------------------------------------------------------------------------------- |  | ------------- |  | ---- | ----- |  | - | ---
|                                               |  | Amount of
GainRecognizedin OtherComprehensiveIncome (Loss) on Derivatives |     | Location of(Loss)
GainReclassifiedFromAccumulatedOtherComprehensiveLoss
intoNet Earnings |   | Amount of (Loss) 
GainReclassified FromAccumulated
OtherComprehensiveLoss into Net Earnings
|                                               |  | Quarter Ended March 31,                                                   |     |                                                                                          |   | Quarter Ended March 31,                                                                    
|                                               |  | 2010                                                                      |     | 2009                                                                                     |   |                                                                                             |  | 2010          |  | 2009
|Derivatives in Cash Flow Hedging Relationships |  |                                                                           |     |                                                                                          |   |                                                                                             |  |               |  |      |       |  |   |    
|                                               |  |                                                                           |     |                                                                                          |  
|Foreign exchange forwards and options          |  | $                                                                         | 5.0 |                                                                                          | $ | 7.6                                                                                         |  | Cost of sales |  | $    | (2.3) |  | $ | 6.8
|                                               |  |                                                                           |     |                                                                                          |   |                                                                                             |  |               |  |      |       |  |   |    



|                                                  |  |                                                            |  |                                               |  |      |       
|------------------------------------------------- |  | ---------------------------------------------------------- |  | --------------------------------------------- |  | ---- | ------
|                                                  |  | Location of Loss Recognized in 
NetEarnings on Derivatives |  | Amount of Loss in 
NetEarnings on Derivatives
|                                                  |  |                                                            |  | Quarter Ended March 31,                      
|                                                  |  |                                                            |  | 2010                                          |  | 2009
|Derivatives not designated as hedging instruments |  |                                                            |  |                                               |  |      |       
|                                                  |  |                                                            | 
|Foreign exchange forwards                         |  | Other non-operating income                                 |  | -                                             |  | $    | (11.8)
|                                                  |  |                                                            |  |                                               |  |      |       

The bank counterparties to the foreign exchange
contracts expose us to credit-related losses in the event of their nonperformance. To help mitigate that risk, we only contract with counterparties that meet certain minimum requirements under our counterparty risk assessment process. The Company
monitors ratings and potential downgrades on at least a quarterly basis. Based on our on-going assessment of counterparty risk, we will adjust our exposure to various counterparties as deemed necessary.



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Note 5.  Fair Value Measurements

The following table presents information about our financial assets and liabilities that are measured at fair value on a recurring basis
at March 31, 2010 and December 31, 2009, and indicates the fair value hierarchy of the valuation techniques we utilize to determine such fair value:





|                                    |  |                                                             |       |                                                             |   |                                            |   |                                        |  |  
|----------------------------------- |  | ----------------------------------------------------------- | ----- | ----------------------------------------------------------- | - | ------------------------------------------ | - | -------------------------------------- |  | -
|                                    |  |                                                             |       | Fair Value Measurements at Reporting Date Using            
|Description of assets (liabilities) |  | Fair Valueat March 
31,2010                                 |       | Quoted Prices inActive
Marketsfor IdenticalAssets (Level 1) |   | Significant OtherObservableInputs(Level 2) |   | SignificantUnobservableInputs(Level 3)
|Derivatives                         |  |                                                             |       |                                                             |   |                                            |   |                                        |  |  
|Forward contracts                   |  | $                                                           | (0.2) |                                                             | - |                                            | $ | (0.2)                                  |  | -
|Option contracts                    |  | $                                                           | 8.9   |                                                             | - |                                            | $ | 8.9                                    |  | -
|                                    |  |                                                            
|Description of assets (liabilities) |  | Fair Valueat 
December 31,2009                              |       | Fair Value Measurements at Reporting Date Using            
|                                    |  | Quoted Prices inActive
Marketsfor IdenticalAssets (Level 1) |       | Significant OtherObservableInputs(Level 2)                  |   | SignificantUnobservableInputs(Level 3)    
|Derivatives                         |  |                                                             |       |                                                             |   |                                            |   |                                        |  |  
|Forward contracts                   |  | $                                                           | (0.6) |                                                             | - |                                            | $ | (0.6)                                  |  | -
|Option contracts                    |  | $                                                           | 2.6   |                                                             | - |                                            | $ | 2.6                                    |  | -

Our financial liabilities have been classified as Level 2. These derivative contracts have been initially valued at the transaction
price and subsequently valued using market data including quotes, benchmark yields, spot rates, and other industry and economic events. See Note 4, Derivatives, for further discussion on derivative financial instruments. When
necessary, we validate our valuation techniques by understanding the models used and obtaining market values from pricing sources.

The carrying values of our financial instruments approximate their fair value at March 31, 2010, except for long-term debt. Quotes
from financial institutions are used to determine market values of our debt and derivative financial instruments. The carrying value and fair value of our long-term debt at March 31, 2010 was $1,333.9 million and $1,506.8 million, respectively.



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Note 6.  Comprehensive Income (Loss)

The reconciliation of net earnings to comprehensive income is as follows:



|                                                                                                                                                                                                                 |  |                         |        |      |   |       
|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ----------------------- | ------ | ---- | - | ------
|                                                                                                                                                                                                                 |  | Quarter Ended March 31,
|                                                                                                                                                                                                                 |  | 2010                    |        | 2009
|Net earnings                                                                                                                                                                                                     |  | $                       | 38.7   |      | $ | 20.6  
|                                                                                                                                                                                                                 |  |                         |        |      |   |       
|Other comprehensive income                                                                                                                                                                                       |  |                         |        |      |   |       
|Foreign currency translation adjustments                                                                                                                                                                         |  |                         | (40.4) |      |   | (52.2)
|Net actuarial gains associated with pension and other postretirement benefits, net of income taxes of $(0.9) and $(14.4) for the
quarter ended March 31, 2010 and 2009, respectively                             |  |                         | 2.6    |      |   | 23.3  
|Amortization of prior service cost and unrecognized gains and losses included in net periodic benefit cost, net of income taxes
of $(2.8) and $(2.3) for the quarter ended March 31, 2010 and 2009, respectively |  |                         | 4.8    |      |   | 4.0   
|Derivatives qualifying as hedges:                                                                                                                                                                                |  |                         |        |      |   |       
|Net derivative gains, net of income taxes of $(1.9) and $(2.9) for the quarter ended March 31, 2010 and 2009, respectively                                                                                       |  |                         | 3.1    |      |   | 4.7   
|Reclassifications to cost of sales, net of income taxes of $(0.9) and $2.6 for the quarter ended March 31, 2010 and 2009,
respectively                                                                           |  |                         | 1.4    |      |   | (4.2) 
|                                                                                                                                                                                                                 |  |                         |        |      |   |       
|Other comprehensive income (loss)                                                                                                                                                                                |  |                         | (28.5) |      |   | (24.4)
|                                                                                                                                                                                                                 |  |                         |        |      |   |       
|Total comprehensive income (loss)                                                                                                                                                                                |  | $                       | 10.2   |      | $ | (3.8) 
|                                                                                                                                                                                                                 |  |                         |        |      |   |       

The components of accumulated other comprehensive loss
(AOCI), net of income taxes, are as follows:



|                                                            |  |               |         |                  |   |        
|----------------------------------------------------------- |  | ------------- | ------- | ---------------- | - | -------
|                                                            |  | March 31,2010 |         | December 31,2009
|Cumulative currency translation adjustments                 |  | $             | 76.8    |                  | $ | 117.2  
|Pension and other postretirement plan liability adjustments |  |               | (273.4) |                  |   | (289.7)
|Net unrealized gain on derivative instruments               |  |               | 0.2     |                  |   | (4.3)  
|                                                            |  |               |         |                  |   |        
|Total accumulated other comprehensive loss                  |  | $             | (196.4) |                  | $ | (176.8)
|                                                            |  |               |         |                  |   |        

During the quarter ended March 31, 2010, the Company
recorded an $8.9 million decrease to AOCI included within the pension and postretirement plan liability adjustments line above in connection with the reestablishment of a deferred tax asset previously written off to AOCI. This adjustment had no
impact to earnings for any periods.

Note 7.  Earnings Per Share

The following is a reconciliation of the numerators and denominators used in computing basic and diluted earnings per share
(EPS):



|                                                                                       |  |                         |      |        |        |                 |   |             |  |        |      |                  |        |  |   |     
|-------------------------------------------------------------------------------------- |  | ----------------------- | ---- | ------ | ------ | --------------- | - | ----------- |  | ------ | ---- | ---------------- | ------ |  | - | ----
|                                                                                       |  | Quarter Ended March 31,
|                                                                                       |  | 2010                    |      | 2009  
|                                                                                       |  | NetEarnings             |      | Shares |        | Per ShareAmount |   | NetEarnings |  | Shares |      | Per 
ShareAmount
|Basic EPS:                                                                             |  |                         |      |        |        |                 |   |             |  |        |      |                  |        |  |   |     
|Net earnings                                                                           |  | $                       | 38.7 |        | 70.321 |                 | $ | 0.55        |  | $      | 20.6 |                  | 63.545 |  | $ | 0.32
|Effect of dilutive stock options, non-vested equity shares and share units outstanding |  |                         | -    |        | 1.213  |                 |   | (0.01)      |  |        | -    |                  | 0.577  |  |   | -   
|                                                                                       |  |                         |      |        |        |                 |   |             |  |        |      |                  |        |  |   |     
|Diluted EPS:                                                                           |  |                         |      |        |        |                 |   |             |  |        |      |                  |        |  |   |     
|Net earnings                                                                           |  | $                       | 38.7 |        | 71.534 |                 | $ | 0.54        |  | $      | 20.6 |                  | 64.122 |  | $ | 0.32
|                                                                                       |  |                         |      |        |        |                 |   |             |  |        |      |                  |        |  |   |     



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For the quarters ended March 31, 2010 and 2009, there were 1.2 million shares and
4.7 million shares, respectively, relating to the possible exercise of outstanding stock options not included in the computation of diluted EPS as their effect would have been antidilutive.

The principal amount of the convertible notes issued in December 2006, due in 2036 and callable in 2013 is expected to be settled in
cash. Any conversion spread over the principal amount would be settled in our common shares. Since the average stock price during the quarters ended March 31, 2010 and 2009 was less than the conversion price of the Convertible Notes, no shares
associated with the convertible notes have been assumed to be outstanding in computing diluted EPS.



|Note 8. | Sale of Assets
|------- | --------------

During
the quarters ended March 31, 2010 and 2009, we sold certain receivables (Receivables). The net book value of the Receivables sold during these periods was $24.5 million and $17.2 million, respectively, for which we received cash
proceeds of $24.5 million and $17.2 million, respectively. Substantially all of these sales took place in Japan. These transactions were accounted for as sales. As a result, the Receivables have been excluded from the accompanying Condensed
Consolidated Balance Sheets.



|Note 9. | Composition of Certain Financial Statement Items
|------- | ------------------------------------------------

Inventories consisted of the following:



|                                    |  |                |       |                   |   |      
|----------------------------------- |  | -------------- | ----- | ----------------- | - | -----
|                                    |  | March 31, 2010 |       | December 31, 2009
|Raw materials, parts and assemblies |  | $              | 180.8 |                   | $ | 180.4
|Work in process                     |  |                | 25.0  |                   |   | 29.5 
|Finished products                   |  |                | 390.6 |                   |   | 386.9
|                                    |  |                |       |                   |   |      
|                                    |  | $              | 596.4 |                   | $ | 596.8
|                                    |  |                |       |                   |   |      

Changes in the product warranty obligation included in
accrued expenses were as follows:



|                                |  |                             |      
|------------------------------- |  | --------------------------- | -----
|                                |  | Quarter endedMarch 31, 2010
|Beginning Balance               |  | $                           | 13.8 
|Current period warranty charges |  |                             | 4.1  
|Current period utilization      |  |                             | (4.7)
|                                |  |                             |      
|Ending Balance                  |  | $                           | 13.2 
|                                |  |                             |      



|Note 10. | Goodwill and Other Intangible Assets
|-------- | ------------------------------------

Changes in the carrying amount of goodwill for the quarter ended March 31, 2010 were as follows:



|                                |  |                     |       |              |   |       |  |   |        
|------------------------------- |  | ------------------- | ----- | ------------ | - | ----- |  | - | -------
|                                |  | ClinicalDiagnostics |       | LifeSciences |   | Total
|Goodwill at December 31, 2009   |  | $                   | 932.4 |              | $ | 109.5 |  | $ | 1,041.9
|Olympus goodwill adjustment     |  |                     | 0.5   |              |   | -     |  |   | 0.5    
|Currency translation adjustment |  |                     | 0.2   |              |   | (0.6) |  |   | (0.4)  
|                                |  |                     |       |              |   |       |  |   |        
|Goodwill at March 31, 2010      |  | $                   | 933.1 |              | $ | 108.9 |  | $ | 1,042.0
|                                |  |                     |       |              |   |       |  |   |        



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Other intangible assets consisted of the following:



|                                  |  |                     |       |                         |   |         |  |                                   |       |                     |          |                         |   |       |  |                                   |         |  |   |       |  |         
|--------------------------------- |  | ------------------- | ----- | ----------------------- | - | ------- |  | --------------------------------- | ----- | ------------------- | -------- | ----------------------- | - | ----- |  | --------------------------------- | ------- |  | - | ----- |  | --------
|                                  |  | March 31, 2010      |       | December 31, 2009      
|                                  |  | GrossCarryingAmount |       | AccumulatedAmortization |   | Net     |  | WeightedAverageAmortizationPeriod |       | GrossCarryingAmount |          | AccumulatedAmortization |   | Net   |  | WeightedAverageAmortizationPeriod
|Amortized intangible assets:      |  |                     |       |                         |   |         |  |                                   |       |                     |          |                         |   |       |  |                                   |         |  |   |       |  |         
|Customer/dealer relationships     |  | $                   | 295.4 |                         | $ | (106.8) |  | $                                 | 188.6 |                     | 17 years |                         | $ | 295.4 |  | $                                 | (101.7) |  | $ | 193.7 |  | 17 years
|Technology                        |  |                     | 229.2 |                         |   | (64.2)  |  |                                   | 165.0 |                     | 11 years |                         |   | 229.2 |  |                                   | (58.0)  |  |   | 171.2 |  | 11 years
|Core technology                   |  |                     | 66.6  |                         |   | (1.9)   |  |                                   | 64.7  |                     | 20 years |                         |   | 66.6  |  |                                   | (1.0)   |  |   | 65.6  |  | 20 years
|Other                             |  |                     | 87.0  |                         |   | (41.3)  |  |                                   | 45.7  |                     | 8 years  |                         |   | 87.6  |  |                                   | (40.0)  |  |   | 47.6  |  | 8 years 
|                                  |  |                     |       |                         |   |         |  |                                   |       |                     |          |                         |   |       |  |                                   |         |  |   |       |  |         
|                                  |  |                     | 678.2 |                         |   | (214.2) |  |                                   | 464.0 |                     | 14 years |                         |   | 678.8 |  |                                   | (200.7) |  |   | 478.1 |  | 14 years
|Non-amortizing intangible assets: |  |                     |       |                         |   |         |  |                                   |       |                     |          |                         |   |       |  |                                   |         |  |   |       |  |         
|Tradename                         |  |                     | 73.5  |                         |   | -       |  |                                   | 73.5  |                     |          |                         |   | 73.5  |  |                                   | -       |  |   | 73.5  |  |         
|IPR&D                             |  |                     | 10.2  |                         |   | -       |  |                                   | 10.2  |                     |          |                         |   | 10.2  |  |                                   | -       |  |   | 10.2  |  |         
|                                  |  |                     |       |                         |   |         |  |                                   |       |                     |          |                         |   |       |  |                                   |         |  |   |       |  |         
|                                  |  | $                   | 761.9 |                         | $ | (214.2) |  | $                                 | 547.7 |                     |          |                         | $ | 762.5 |  | $                                 | (200.7) |  | $ | 561.8 |  |         
|                                  |  |                     |       |                         |   |         |  |                                   |       |                     |          |                         |   |       |  |                                   |         |  |   |       |  |         

Estimated future intangible asset amortization expense consists of the following:





|                             |  |   |      
|---------------------------- |  | - | -----
|2010 (remaining nine months) |  | $ | 41.7 
|2011                         |  |   | 54.0 
|2012                         |  |   | 50.5 
|2013                         |  |   | 49.4 
|2014                         |  |   | 47.2 
|Thereafter                   |  |   | 221.2
|                             |  |   |      
|Total                        |  | $ | 464.0
|                             |  |   |      

Note 11.  Debt

Certain of our borrowing agreements contain covenants that we must comply with, including a debt to earnings ratio and a minimum interest
coverage ratio. At March 31, 2010, we were in compliance with such covenants.

Note 12.  Retirement Benefits

For the quarters ended March 31, 2010 and 2009, the pension and postretirement benefit costs were comprised of:



|                                               |  |                          |        |                                  |   |        |  |      |       |      |   |       |  |   |       |  |   |      
|---------------------------------------------- |  | ------------------------ | ------ | -------------------------------- | - | ------ |  | ---- | ----- | ---- | - | ----- |  | - | ----- |  | - | -----
|                                               |  | Pensions                 |        | U.S.Postretirement
Benefit Plans
|                                               |  | U.S. Plans               |        | Non-U.S.Plans                    |  
|                                               |  | Quarters Ended March 31,
|                                               |  | 2010                     |        | 2009                             |   | 2010   |  | 2009 |       | 2010 |   | 2009 
|Service cost-benefits earned during the period |  | $                        | 3.8    |                                  | $ | 4.0    |  | $    | 1.9   |      | $ | 1.2   |  | $ | 0.3   |  | $ | 0.4  
|Interest cost on benefit obligation            |  |                          | 10.7   |                                  |   | 10.8   |  |      | 3.2   |      |   | 2.4   |  |   | 1.8   |  |   | 1.7  
|Expected return on plan assets                 |  |                          | (13.1) |                                  |   | (11.6) |  |      | (2.8) |      |   | (2.1) |  |   | -     |  |   | -    
|Amortization:                                  |  |                          |        |                                  |   |        |  |      |       |      |   |       |  |   |       |  |   |      
|Prior service cost (credit)                    |  |                          | 0.2    |                                  |   | 0.2    |  |      | (0.2) |      |   | (0.2) |  |   | (0.1) |  |   | (0.1)
|Actuarial loss (gain)                          |  |                          | 6.7    |                                  |   | 5.6    |  |      | 1.0   |      |   | 0.8   |  |   | -     |  |   | (0.1)
|                                               |  |                          |        |                                  |   |        |  |      |       |      |   |       |  |   |       |  |   |      
|Net periodic benefit costs                     |  | $                        | 8.3    |                                  | $ | 9.0    |  | $    | 3.1   |      | $ | 2.1   |  | $ | 2.0   |  | $ | 1.9  
|                                               |  |                          |        |                                  |   |        |  |      |       |      |   |       |  |   |       |  |   |      

We contributed $20.0 million to our U.S. pension plan
during the quarter ended March 31, 2010. We expect to contribute approximately $13.3 million to our U.S. and international pension plans and approximately $6.0 million to our postretirement plan during 2010. Our pension plans are currently
underfunded and we may decide to make additional pension plan contributions in the future.



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##### Table of Contents

Note 13.  Commitments and Contingencies

Environmental Matters

We
are subject to federal, state, local and foreign environmental laws and regulations. Although we continue to incur expenditures for environmental protection, we do not anticipate any expenditure to comply with such laws and regulations that would
have a material impact on our consolidated operations or financial position except as discussed below. We believe that our operations comply in all material respects with applicable federal, state and local environmental laws and regulations.

In connection with our Orange County consolidation project and closure of our Fullerton, California site, we began conducting
environmental studies at our Fullerton site. The data generated by these studies indicates that soils under and around several of the buildings contain chemicals previously used in operations at the facility. Some of these chemicals also have been
found in groundwater underlying the site. Studies to determine the source and extent of these chemicals are underway and are expected to continue for several months. We have notified the State Department of Toxic Substances Control of the presence
of these chemicals at the site and expect that agency to oversee determination of any remediation requirements. We recorded a liability of $19 million in 2008, representing our best estimate of the future expenditures for investigation and
remediation at the site; however, it is possible that the ultimate costs incurred could range from $10 million to $30 million. Our estimates are based upon the results of our investigation to date and comparison to our prior experience with
environmental remediation at another site. Therefore, it is possible that additional activities not contemplated at this time could be required and that the actual costs could differ materially from the amount we have recorded as a liability or our
estimated range. Through March 31, 2010, we have spent $1.5 million in relation to investigation and remediation activities.

To address contingent environmental costs, we establish reserves when the costs are probable and can be reasonably estimated. We believe
that, based on current information and regulatory requirements, the reserves established by us for environmental expenditures are adequate. Based on current knowledge, to the extent that additional costs may be incurred that exceed the reserves, the
amounts are not expected to have a material adverse effect on our operations, consolidated financial condition or liquidity.

Legal
Proceedings

We are involved in a number of lawsuits, which we consider ordinary and routine in view of our size and the
nature of our business. We accrue for our best estimate within the range of the loss or the minimum probable liability if no best estimate can be determined. Such accruals at March 31, 2010 were immaterial. We do not believe any ultimate
liability resulting from any of these lawsuits will have a material adverse effect on our results of operations, financial position or liquidity. We cannot, however give any assurances regarding the ultimate outcome of these lawsuits, and their
resolution could be material to our operating results for any particular period, depending upon the level of income for the period.

Note 14.  Business Segment Information

We are engaged primarily in the design, manufacture and sale of laboratory instrument systems and related products with two operating
segments, Clinical Diagnostics and Life Science. The Clinical Diagnostics segment, which includes products used to evaluate and analyze bodily fluids, cells and other patient samples, represents approximately 88% of our consolidated revenue for the
quarter ended March 31, 2010. The product areas within Clinical Diagnostics are chemistry and clinical automation, cellular analysis, and immunoassay and molecular diagnostics. Our Life Science segment includes systems used in disease research
performed in academic centers and therapeutic research performed by biopharmaceutical companies as well as certain industrial applications for scientific instrumentation.

Management evaluates business segment performance on a revenue and operating income basis. Operating income for segment reporting,
disclosed below, is revenue less operating costs. Certain costs, such as corporate overhead and other charges which are not directly related to our segments are not allocated to the segments financial results. Therefore, the financial results of our
segments exclude these costs for performance assessment by our chief operating decision maker. Unallocated corporate overhead costs include employee benefits, occupancy, information systems, accounting services, internal legal staff, and human
resources administration expenses related to our corporate function, while other items excluded from our segment results include restructuring charges, technology license fees and other charges. In prior years, these costs were allocated to the
segments based on actual usage or other appropriate methods. However, these expenses are not considered direct costs of the operating segments, therefore our chief operating decision maker now evaluates the segments excluding these costs. In the
tables below, these costs have been excluded from the current year segment results and reclassified in the prior year results to conform with the current year presentation. Non-operating income (expense) and interest income and expense are not
allocated to the segments. We do not discretely allocate assets to our operating segments, nor does our chief operating decision maker evaluate operating segments using discrete asset information.



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##### Table of Contents

The following table sets forth revenue and operating income data with respect to our two
operating segments and a reconciliation of our segments operating income to consolidated earnings before income taxes:



|                                                                       |  |                         |        |      |   |       
|---------------------------------------------------------------------- |  | ----------------------- | ------ | ---- | - | ------
|                                                                       |  | *Quarter EndedMarch 31,
|                                                                       |  | 2010                    |        | 2009
|Segment revenues:                                                      |  |                         |        |      |   |       
|Clinical Diagnostics                                                   |  |                         |        |      |   |       
|Chemistry and Clinical Automation                                      |  | $                       | 323.0  |      | $ | 207.0 
|Cellular Analysis                                                      |  |                         | 239.1  |      |   | 213.5 
|Immunossay and Molecular Diagnostics                                   |  |                         | 213.7  |      |   | 176.9 
|                                                                       |  |                         |        |      |   |       
|Total Clinical Diagnostics                                             |  |                         | 775.8  |      |   | 597.3 
|Life Science                                                           |  |                         | 105.3  |      |   | 94.2  
|                                                                       |  |                         |        |      |   |       
|Total revenues                                                         |  | $                       | 881.1  |      | $ | 691.5 
|                                                                       |  |                         |        |      |   |       
|Segment operating income:                                              |  |                         |        |      |   |       
|Clinical Diagnostics                                                   |  | $                       | 143.8  |      | $ | 94.0  
|Life Science                                                           |  |                         | 17.7   |      |   | 9.3   
|                                                                       |  |                         |        |      |   |       
|Total segment operating income                                         |  |                         | 161.5  |      |   | 103.3 
|Unallocated corporate overhead and other costs                         |  |                         | (57.9) |      |   | (37.3)
|Restructuring expenses                                                 |  |                         | (4.3)  |      |   | (16.6)
|Acquisition related costs for Clinical Diagnostics                     |  |                         | (13.9) |      |   | (9.8) 
|Olympus intangibles asset amortization related to Clinical Diagnostics |  |                         | (5.5)  |      |   | -     
|                                                                       |  |                         |        |      |   |       
|Total operating income                                                 |  |                         | 79.9   |      |   | 39.6  
|                                                                       |  |                         |        |      |   |       
|Non-operating (income) expense:                                        |  |                         |        |      |   |       
|Interest income                                                        |  |                         | (1.3)  |      |   | (1.3) 
|Interest expense                                                       |  |                         | 24.1   |      |   | 10.9  
|Other                                                                  |  |                         | (0.3)  |      |   | 11.8  
|                                                                       |  |                         |        |      |   |       
|Total non-operating expense                                            |  |                         | 22.5   |      |   | 21.4  
|                                                                       |  |                         |        |      |   |       
|Earnings before income taxes                                           |  | $                       | 57.4   |      | $ | 18.2  
|                                                                       |  |                         |        |      |   |       



|* | Amounts may not foot due to rounding.
|- | -------------------------------------

Our principal markets are the U.S. and international markets. The U.S. information is presented separately since we are headquartered in
the U.S. Revenues in the U.S. represented 46% and 51% of our total consolidated revenues for the quarters ended March 31, 2010 and 2009, respectively. No other country accounts for greater than 10% of revenues.



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The following table sets forth revenue and long-lived asset data by geography:



|                      |  |                         |       |      |   |      
|--------------------- |  | ----------------------- | ----- | ---- | - | -----
|                      |  | *Quarter EndedMarch 31,
|                      |  | 2010                    |       | 2009
|Revenue by geography: |  |                         |       |      |   |      
|United States         |  | $                       | 402.1 |      | $ | 356.1
|Europe                |  |                         | 205.6 |      |   | 144.8
|Emerging Markets (a)  |  |                         | 71.6  |      |   | 50.9 
|Asia Pacific          |  |                         | 149.3 |      |   | 96.7 
|Other (b)             |  |                         | 52.5  |      |   | 43.0 
|                      |  |                         |       |      |   |      
|Total revenues        |  | $                       | 881.1 |      | $ | 691.5
|                      |  |                         |       |      |   |      



|                        |  |               |         |                   |   |        
|----------------------- |  | ------------- | ------- | ----------------- | - | -------
|                        |  | March 31,2010 |         | December 
31,2009
|Long-lived assets:      |  |               |         |                   |   |        
|United States           |  | $             | 1,997.2 |                   | $ | 1,967.8
|International           |  |               | 777.9   |                   |   | 839.4  
|                        |  |               |         |                   |   |        
|Total long lived assets |  | $             | 2,775.1 |                   | $ | 2,807.2
|                        |  |               |         |                   |   |        



|* | Amounts may not foot due to rounding.
|- | -------------------------------------

|(a) | Emerging Markets includes Eastern Europe, Russia, Middle East, Africa and India.
|--- | --------------------------------------------------------------------------------

|(b) | Other includes Canada and Latin America
|--- | ---------------------------------------



|Item 2. | Managements Discussion and Analysis of Financial Condition and Results of Operations
|------- | -------------------------------------------------------------------------------------

This Form 10-Q for the quarterly period ended March 31, 2010 (Form 10-Q) contains forward-looking statements
within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. Many of the forward-looking statements are located in this Managements Discussion
and Analysis of Financial Condition and Results of Operations section. Forward-looking statements reflect our current views with respect to future events and can also be identified by words such as may, will,
might, expect, believe, anticipate, could, would, estimate, continue, pursue, plans, should, likely,
might, or the negative thereof or comparable terminology, and may include, without limitation, information regarding our expectations, goals or intentions regarding the future. Forward-looking statements involve certain risks and
uncertainties, and our actual results may differ materially from those discussed in any forward-looking statement. Factors that could cause results to differ include, but are not limited to, the Risk Factors discussed in Part I, Item 1A in
our Annual Report on Form 10-K for the year ended December 31, 2009 and in our other current and periodic reports filed from time to time with the SEC, including the Risk Factors discussed in Part II, Item 1A of this Form 10-Q. Therefore,
the reader is cautioned not to rely on these forward-looking statements. All forward-looking statements in this Form 10-Q are made as of the date hereof and we assume no obligation to update any forward-looking statement, except as required by
law.

The following discussion should be read in conjunction with our Condensed Consolidated Financial Statements and
Notes to Condensed Consolidated Financial Statements included in Part I, Item 1 of this Form 10-Q and in our Annual Report on Form 10-K. Managements Discussion and Analysis of Financial Condition and Results of Operations
(MD&A) is designed to provide a reader of our financial statements with a narrative from the perspective of our management on our financial condition, results of operations, liquidity and certain other factors that may affect our
future results.

In the accompanying analysis of our financial condition and results of operation, we sometimes use
information derived from consolidated financial information but not presented in our financial statements prepared in accordance with generally accepted accounting principles in the United States of America, (U.S. GAAP). Certain of these
data are considered non-GAAP financial measures under SEC rules. For such measures, we have provided supplemental explanations and reconciliations below under Supplemental Information.



17



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Overview

Beckman Coulter is the worlds largest company devoted solely to biomedical testing, a market we estimate had approximately $41
billion in worldwide sales in 2009. We market our products in more than 160 countries, with approximately half of our revenue in 2009 coming from outside the United States. Our strategy is to extend the Companys leadership in simplifying,
automating and innovating customers processes, by continuing to rollout new products, enhance our current product offerings and enter into new and growing market segments. We design, manufacture, and sell systems, services, reagents and
supplies to clinical and life science laboratories around the world. Our products combine sophisticated analytical instruments, user-friendly software and highly sensitive chemistries, integrated into complete and simple to use systems. Our product
lines address nearly all blood tests routinely performed in hospital central laboratories and a range of scientific instrumentation for life science and pharmaceutical research.

The majority of our revenue is generated from consumable supplies (including reagent test kits), service and operating-type lease
(OTL) payment arrangements. Approximately 83% of our total revenue for the first quarter of 2010 was generated by this type of revenue, which we refer to as recurring revenue. A customer contract typically runs five to seven
years. Switching instrument systems creates significant costs for laboratories: changing suppliers means re-training staff on new systems and performing validation studies to assure consistency of reported results.

Our instruments are mainly provided to customers under cash sales or OTL arrangements. Since mid-2005, most of our leases have been OTLs
rather than sales-type leases (STLs), which we previously utilized. Our OTLs are provided under bundled lease arrangements, in which our customers pay a monthly amount for the equipment, consumable supplies (including reagent test kits),
and service. Our lease arrangements primarily take the form of what are known as reagent rentals where an instrument is placed at a customer location and the customer commits to purchase a certain minimum volume of reagents annually. We
also enter into metered contracts with customers where the instrument is placed at a customer location with a stock of reagents and the customer is billed monthly based on actual reagent usage.

Strategic Initiatives

Our core strategy is to simplify, automate and innovate complex biomedical testing processes. Our strategic initiatives for 2010 continue
our focus on growth, quality and operating excellence:



| |  |  | We are committed to ensuring patient safety and regulatory compliance. As discussed in more detail below under Product Compliance and Quality
Matters, the U.S. Food and Drug Administration (FDA) has indicated to us that it believes that certain modifications to our troponin test kits as used on DxI immunoassay systems and as used on Access immunoassay systems were made
without obtaining appropriate product clearances from FDA. Given the issues pertaining to our troponin test kits as well as our recent recall relating to sodium testing on our DxC chemistry systems and other quality and compliance matters, we are
currently evaluating our internal processes and procedures regarding our product, quality and regulatory systems. We remain committed and are heavily focused on quality and compliance for the balance of 2010 and beyond. Quality is the single most
important function of every employee at Beckman Coulter and we are determined to restore confidence in Beckman Coulter.
| | - |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | We are integrating our recent acquisition of the diagnostics systems portion of Olympus Corporations business (Olympus). In 2009 we
completed the Olympus acquisition to extend our Clinical Diagnostics chemistry and automation product offering and enhance our geographic reach and scale. We expect to substantially complete the Olympus integration by mid-2010.
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | We are working to expand our test menu, particularly in our immunoassay and molecular diagnostics products, and believe our focus on certain disease
states will enable us to deliver enhanced testing capability to our customers, which are expected to ultimately improve patient health and reduce the cost of care.
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | We are building on our industry-leading ability to help customers simplify, automate and innovate their processes. Our expansive knowledge of
customers laboratory processes supports our expansion of automation and work cells, growing our installed base of instruments.
| | - |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | From a geographic perspective, we are increasing resources in developing markets, including China, which we believe will improve our opportunities for
long-term growth.
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | We intend to continue to reduce product, service and operating costs by streamlining our supply chain operations and expanding our use of Lean
Six Sigma tools to other business processes throughout the company.
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | We have announced that we plan to design and build an automated, fully integrated molecular diagnostic sample to result system to enable moderately
complex testing in hospital central laboratories. Product development costs for the project are anticipated to be about $30 million per year at least through 2012, excluding any test menu licensing fees.
| | - |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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As part of our strategic initiatives, we expect to incur charges as we integrate Olympus,
realign our manufacturing and distribution footprint and implement initiatives to improve productivity and reduce operating costs in the future.

Product Compliance and Quality Matters

As reported through our SEC filings, we have recalled the troponin test, a critical care test used to aid in the diagnosis of cardiac
events, from one of our automated immunoassay systems, the DxI, and advised our DxI customers to find an alternate method for troponin testing. In the U.S., we recognized approximately $60 million in total annual revenue from troponin in 2009. Of
this total, we estimate that $10 to $15 million is at risk.

Below is the status to date:



| |  |  | FDA has classified our troponin recall as a Class II event and has agreed to give customers an extension to August 1, 2010 to switch from running
troponin on DxI immunoassay systems to an alternate method.
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | We continue to work with FDA to establish a pathway to an unambiguous cleared status in the U.S. We have submitted our clinical study proposal to FDA
to clear troponin for use on all of our automated immunoassay systems and anticipate a response soon. Until we have reached agreement with FDA there can be no assurance as to the scope of the clinical study that will be required to clear the test.
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Based on a review of 58 of our immunoassay tests and our customer complaint files, we dont believe there are any other significant cross platform
bias issues with these immunoassay tests and further believe we have no others that might approach the magnitude of troponin.
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | As a result of our compliance and quality improvement initiative, we are undertaking improvements to other products, including our sensor based tests
used for glucose and sodium testing on our LX and DxC chemistry systems.
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | As we indicated in our March 22, 2010 SEC filing, we are evaluating our internal processes and procedures regarding product compliance and quality
systems. It is possible that other products could be impacted resulting in corrective actions that might adversely affect our operating results.
| | - |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Because we value customer feedback, we have engaged customers in a series of regional forums and established a customer advisory group to
provide additional insight into both product performance and customer communications.

Critical Accounting Policies and Estimates

Our Condensed Consolidated Financial Statements are prepared in accordance with U.S. GAAP. In connection with the
preparation of our financial statements, we are required to make assumptions and estimates about future events and apply judgments that affect the reported amounts of assets, liabilities, revenue, expenses and the related disclosures. We base our
assumptions, estimates and judgments on historical experience, current trends and other factors that management believes to be relevant at the time our consolidated financial statements are prepared. On a regular basis, our accounting policies,
assumptions, estimates and judgments are reviewed by management to ensure that our financial statements are presented fairly in accordance with U.S. GAAP. However, because future events and their effects cannot be determined with certainty, actual
results could differ materially from our assumptions and estimates.

Both our accounting policies and estimates are essential
in understanding MD&A and results of operations. We describe our significant accounting policies in Note 1, Nature of Business and Summary of Significant Accounting Policies, of the Notes to the Consolidated Financial
Statements included in our Annual Report on Form 10-K for the year ended December 31, 2009. In addition, we discuss our critical accounting estimates in MD&A in our Annual Report on Form 10-K for the year ended December 31, 2009. There
were no significant changes in our accounting policies or estimates since the end of 2009.

Results of Operations

We measure our business on the basis of two reportable segments  Clinical Diagnostics and Life Science. The Clinical Diagnostics
segment represents approximately 88% of our consolidated revenue and includes products used to evaluate and analyze bodily fluids, cells and other patient samples. The three product areas within Clinical Diagnostics are chemistry and clinical



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##### Table of Contents

automation, cellular analysis and immunoassay and molecular diagnostics. Our Life Science segment includes systems used for disease research performed in academic centers and therapeutic research
performed by biopharmaceutical companies.

To facilitate an understanding of our financial results, we review revenue on both
a reported and constant currency basis (constant currency growth is not a U.S. GAAP defined measure of revenue growth). We define constant currency revenue as current period revenue in local currency translated to U.S. dollars at the prior
years foreign currency exchange rate for that period, computed monthly. Constant currency growth as presented herein represents:

Current period constant currency revenue less prior year reported revenue / Prior year reported revenue

This measure provides information on revenue growth assuming that foreign currency exchange rates have not changed between the prior year
and the current period. We believe the use of this measure aids in the understanding of our operations without the impact of foreign currency fluctuations. Constant currency revenue and constant currency growth as defined or presented by us may not
be comparable to similarly titled measures reported by other companies. Additionally, constant currency revenue is not an alternative measure of revenue on a U.S. GAAP basis.

Current Quarter Financial Highlights

We create value for customers and shareholders by understanding the process and impact of clinical testing and applying our skills and
experience to simplify, automate and innovate complex laboratory processes. Through these activities, we believe we can improve patient health and reduce the cost of care.

Following is a summary of key 2010 financial and nonfinancial information:



| |  |  | Recurring revenue of $731.3 million, increased by $157.6 million, of which $90.3 million resulted from the acquired Olympus products. Excluding the
Olympus products, we experienced growth in recurring revenue of 8.4% in constant currency;
| | - |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Instrument sales of $149.8 million increased by $32.0 million from 2009, including $25.4 million of instrument sales related to Olympus products;
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Reported operating income of $79.9 million increased by $40.3 million largely as a result of growth in revenue, control of operating expenses, and
lower restructuring and acquisition related costs
| | - |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Effective control of operating expenses combined with growth in revenue were partially offset by the increase in interest expense and increased share
count due to the Olympus financing, resulting in reported net earnings per diluted share of $0.54 compared to $0.32 per share in 2009
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | 2010 capital expenditures of $34.3 million for property, plant and equipment and $36.9 million on operating-type leases.
| | - |  | ------------------------------------------------------------------------------------------------------------------------

Recurring revenue, which we believe is the best indicator of our business overall strength, grew 27.5% (23.7% in constant
currency), of which 15.7 % of the growth was from Olympus products. Excluding revenue from the Olympus acquisition, the recurring revenue growth was primarily driven by continued growth in our Automated immunoassay products, particularly in
international markets. We expect our steady gains in recurring revenue, which represents approximately 83% of our total revenue, to provide a predictable source of earnings expansion and cash flow. Recurring revenue allows us to generate substantial
operating cash flows, which we use to facilitate growth in our business by developing, marketing and launching new products through internal development and business and technology acquisitions. Our investment in customer leased instruments and our
operating cash flow should continue to build more moderately beyond 2010 since we have almost completed the five-year transition to our OTL model.

Operating income increased as a result of the increased recurring revenue, effective control over expenses, and the decline in
restructuring and acquisition related costs in the first quarter of 2010.

Non-operating income increased slightly during the
first quarter of 2010 compared to 2009. We did incur significantly higher interest expense during 2010 due to financing of the Olympus acquisition, however, the prior year quarter reflects an $11.8 million hedging loss associated with forward
contracts to purchase Japanese yen which hedged our Olympus purchase price.

Our effective tax rate increased to 32.6% from a
tax benefit of 13.2% during the first quarter of 2009, due primarily to a reduction of a deferred tax asset in the first quarter 2010 related to Medicare drug subsidies as well as favorable settlements of tax audits in the first quarter of 2009. The
tax rate was also affected by geographic mix of profits.



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##### Table of Contents

Revenue

The following table compares revenue type, segment and geography for the quarters ended March 31, 2010 and 2009 (dollar amounts in
millions):



|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|-------------------------------------------------------- | ---- | ----------------------- | ----- | ---------------- | - | ---------------------------- |  | ----- |  | -----
|                                                         |      | *QuarterEnded March 31, |       | ReportedGrowth % |   | ConstantCurrencyGrowth % (a)
|                                                         | 2010 |                         | 2009  |                  |  
|Total revenue:                                           |      |                         |       |                  |   |                              |  |       |  |      
|Recurring revenue  supplies, service and lease payments |      | $                       | 731.3 |                  | $ | 573.7                        |  | 27.5% |  | 23.7%
|Instrument sales                                         |      |                         | 149.8 |                  |   | 117.8                        |  | 27.2% |  | 23.3%
|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|Total revenue                                            |      |                         | 881.1 |                  |   | 691.5                        |  | 27.4% |  | 23.6%
|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|                                                         |      |                         |       |                 
|Segment revenue:                                         |      |                         |       |                  |   |                              |  |       |  |      
|Clinical Diagnostics:                                    |      |                         |       |                  |   |                              |  |       |  |      
|Chemistry and Clinical Automation                        |      |                         | 323.0 |                  |   | 207.0                        |  | 56.1% |  | 51.8%
|Cellular Analysis                                        |      |                         | 239.1 |                  |   | 213.5                        |  | 12.0% |  | 8.4% 
|Immunoassay and Molecular Diagnostics                    |      |                         | 213.7 |                  |   | 176.9                        |  | 20.8% |  | 17.4%
|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|Total Clinical Diagnostics                               |      |                         | 775.8 |                  |   | 597.3                        |  | 29.9% |  | 26.1%
|Life Science                                             |      |                         | 105.3 |                  |   | 94.2                         |  | 11.8% |  | 7.9% 
|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|Total revenue                                            |      | $                       | 881.1 |                  | $ | 691.5                        |  | 27.4% |  | 23.6%
|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|                                                         |      |                         |       |                 
|Revenue by geography:                                    |      |                         |       |                  |   |                              |  |       |  |      
|United States                                            |      | $                       | 402.1 |                  | $ | 356.1                        |  | 12.9% |  | 12.9%
|Europe                                                   |      |                         | 205.6 |                  |   | 144.8                        |  | 42.0% |  | 35.1%
|Emerging Markets (b)                                     |      |                         | 71.6  |                  |   | 50.9                         |  | 40.6% |  | 32.6%
|Asia Pacific                                             |      |                         | 149.3 |                  |   | 96.7                         |  | 54.5% |  | 47.5%
|Other (c)                                                |      |                         | 52.5  |                  |   | 43.0                         |  | 22.3% |  | 9.4% 
|                                                         |      |                         |       |                  |   |                              |  |       |  |      
|Total revenue                                            |      | $                       | 881.1 |                  | $ | 691.5                        |  | 27.4% |  | 23.6%
|                                                         |      |                         |       |                  |   |                              |  |       |  |      



| | * | Amounts in table above may not foot or recalculate due to rounding.
| | - | -------------------------------------------------------------------

| | (a) | Constant currency growth is not a U.S. GAAP defined measure of revenue growth.
| | --- | ------------------------------------------------------------------------------

| | (b) | Emerging Markets includes Eastern Europe, Russia, Middle East, Africa and India.
| | --- | --------------------------------------------------------------------------------

| | (c) | Other includes Canada and Latin America.
| | --- | ----------------------------------------



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Recurring revenue increased 27.5% (23.7% in constant currency) during the quarter ended
March 31, 2010 in comparison to the same period in the prior year. The increase in recurring revenue was driven in large part by the acquisition of Olympus, which added 15.7% to this growth during the quarter ended March 31, 2010. Strong
growth in immunoassay and continued growth in cellular analysis also contributed to the increase. Recurring revenue, which we believe is the best indicator of the overall strength of our business, represented 83% of our total revenue during the
quarter.

Instrument sales increased by 27.2% (23.3% in constant currency) to $149.8 million during the quarter ended
March 31, 2010, with about two-thirds of the growth from the Olympus acquisition and the remainder from increased sales of our flow cytometry systems and life science automation systems.

Clinical Diagnostics

Clinical Diagnostics revenue increased by 29.9% in the quarter ended March 31, 2010 when compared to the same period in 2009,
primarily as a result of the Olympus acquisition and organic growth in recurring revenue. In constant currency, revenue increased 26.1% for the first quarter of 2010, primarily driven by a 25.4% constant currency improvement in recurring revenue
during the quarter ended March 31, 2010. The Olympus acquisition accounted for about half of the growth in recurring revenue during the quarter ended March 31, 2010. Continued robust growth in Automated Immunoassay and hematology also
contributed to the increase in recurring revenue. Recurring revenue growth largely reflects an expanding installed base, particularly in China and other emerging markets, and increased test kit utilization. Instrument sales increased 31.4% in
constant currency for the quarter ended March 31, 2010 in comparison to the related prior year period due primarily to the Olympus acquisition.

Revenue by Product Area  Clinical Diagnostics

Chemistry and Clinical Automation

Revenue from chemistry and clinical automation increased by 56.1% (51.8% in constant currency) for the quarter ended March 31, 2010
versus the same period in 2009. The Olympus acquisition represented substantially all of the growth of this product area.

Cellular Analysis

Revenue from cellular analysis increased 12.0% (8.4% increase in constant currency) for the quarter ended March 31, 2010 as compared
to the same period in 2009. The growth was driven by strong instrument sales in flow cytometry.

Immunoassay and Molecular
Diagnostics

Revenue in immunossay and molecular diagnostics increased by 20.8% (17.4% in constant currency) for the
quarter ended March 31, 2010 when compared to the same period in the prior year. The growth was primarily from a 19.1% increase in Automated immunoassay recurring revenue and robust growth in molecular diagnostics products. Additionally, the
acquisition of Cogenics in April 2009 contributed slightly to revenue growth during the first quarter of 2010.

Life Science

Revenue from our Life Science products increased by 11.8% (7.9% in constant currency) for the quarter ended March 31,
2010 as compared to the prior year period. Instrument sales were a significant driver of the increase in sales, improving by approximately 12% in constant currency for the quarter ended March 31, 2010 led by life science automation.

Revenue by Major Geography

Overall, revenue in the U.S. was up 12.9% for the quarter ended March 31, 2010 versus the quarter ended March 31, 2009. Higher
revenue was primarily due to the Olympus acquisition.

Revenue in Europe increased by 42.0% (35.1% in constant currency) for
the quarter ended March 31, 2010 versus the same period in 2009. The constant currency growth was due to the Olympus acquisition and to solid growth in immunoassay and molecular diagnostics.

Revenue from Emerging Markets increased by 40.6% (32.6% in constant currency) for the quarter ended March 31, 2010 versus the same
period in 2009, primarily from the Olympus acquisition and Automated Immunoassay recurring revenue growth.

Sales in Asia
Pacific increased by 54.5% (47.5% in constant currency) for the quarter ended March 31, 2010 versus the same period in 2009. The increase was primarily due to Olympus and a robust increase in recurring revenue from our immunoassay and molecular
diagnostics, flow cytometry and Life Science product areas.



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##### Table of Contents

Cost of Sales



|                                     |  |               |       |               |   |               |  |       
|------------------------------------ |  | ------------- | ----- | ------------- | - | ------------- |  | ------
|                                     |  | Quarter Ended
|                                     |  | March 31,2010 |       | March 31,2009 |   | PercentChange
|(in millions)                        |  |               |       |               |   |               |  |       
|Cost of recurring revenue            |  | $             | 354.5 |               | $ | 268.3         |  | 32.1% 
|As a percentage of recurring revenue |  |               | 48.5% |               |   | 46.8%         |  | 1.7%  
|                                     |  |               |      
|Cost of instrument sales             |  | $             | 121.6 |               | $ | 104.1         |  | 16.8% 
|As a percentage of instrument sales  |  |               | 81.2% |               |   | 88.4%         |  | (7.2)%
|                                     |  |               |      
|Total cost of sales                  |  | $             | 476.1 |               | $ | 372.4         |  | 27.8% 
|As a percentage of total revenue     |  |               | 54.0% |               |   | 53.9%         |  | 0.1%  

Cost of sales
increased 27.8% during the quarter ended March 31, 2010 as compared to the corresponding prior year period which is directly related to the overall revenue increase of 27.4%.

Operating Expenses

Selling, General and Administrative



|                                    |  |               |       |               |   |               |  |       
|----------------------------------- |  | ------------- | ----- | ------------- | - | ------------- |  | ------
|                                    |  | Quarter Ended
|                                    |  | March 31,2010 |       | March 31,2009 |   | PercentChange
|(in millions)                       |  |               |       |               |   |               |  |       
|Selling, general and administrative |  | $             | 222.9 |               | $ | 185.9         |  | 19.9% 
|As a percentage of total revenue    |  |               | 25.3% |               |   | 26.9%         |  | (1.6)%

Selling, general and
administrative (SG&A) expense for the quarter ended March 31, 2010 increased by $37.0 million, primarily due to additional expenses associated with the Olympus business and increased spending on selling and marketing activities
to support our revenue growth.

Research and Development



|                                 |  |               |      |               |   |               |  |       
|-------------------------------- |  | ------------- | ---- | ------------- | - | ------------- |  | ------
|                                 |  | Quarter Ended
|                                 |  | March 31,2010 |      | March 31,2009 |   | PercentChange
|(in millions)                    |  |               |      |               |   |               |  |       
|Research and development         |  | $             | 70.1 |               | $ | 59.9          |  | 17.0% 
|As a percentage of total revenue |  |               | 8.0% |               |   | 8.7%          |  | (0.7)%

The increase in
research and development (R&D) of $10.2 million for the quarter ended March 31, 2010 was primarily due to additional costs associated with the Olympus business as well as additional product development investments in our
molecular diagnostics program, DxN.



|                                            |  |               |      |               |   |               |  |        
|------------------------------------------- |  | ------------- | ---- | ------------- | - | ------------- |  | -------
|                                            |  | Quarter Ended
|                                            |  | March 31,2010 |      | March 31,2009 |   | PercentChange
|(in millions)                               |  |               |      |               |   |               |  |        
|Amortization of intangibles                 |  | $             | 13.9 |               | $ | 7.3           |  | 90.4%  
|Restructuring and acquisition related costs |  | $             | 18.2 |               | $ | 26.4          |  | (31.1)%



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##### Table of Contents

Amortization of intangibles

Amortization of intangibles increased by $6.6 million during the first quarter of 2010 due primarily to the acquired intangibles from the
Olympus acquisition. Amortization of intangible assets is related primarily to acquired technology, customer and dealer relationships.

Restructuring and Acquisition Related Costs

Restructuring and acquisition related costs decreased by $8.2 million during the quarter ended March 31, 2010, when compared to the
prior year period due primarily to lower costs for restructuring initiatives which are nearing completion. During the prior year, we experienced high restructuring costs primarily due to the closure and relocation of certain manufacturing and
distribution sites along with activities related to our plan to vacate our Fullerton, California facility and consolidate those operations to other existing facilities. The restructuring costs related to the closure and relocation of these sites
includes severance, relocation, and other exit costs. The majority of the restructuring and acquisition related costs incurred during the first quarter of 2010 relates to costs to integrate the Olympus acquisition.

Operating Income

Management evaluates business segment performance based on revenue and operating income exclusive of certain adjustments, which are not
allocated to our segments for performance assessment by our chief operating decision maker.

The following table presents
operating income for each reportable segment for the quarter ended March 31, 2010 and 2009 and a reconciliation of our segment operating income to consolidated earnings before income taxes (dollar amounts in millions):



|                                                                       |  |                        |        |      |   |       
|---------------------------------------------------------------------- |  | ---------------------- | ------ | ---- | - | ------
|                                                                       |  | Quarter EndedMarch 31,
|                                                                       |  | 2010                   |        | 2009
|Operating income:                                                      |  |                        |        |      |   |       
|Clinical Diagnostics                                                   |  | $                      | 143.8  |      | $ | 94.0  
|Life Science                                                           |  |                        | 17.7   |      |   | 9.3   
|                                                                       |  |                        |        |      |   |       
|Total segment operating income                                         |  |                        | 161.5  |      |   | 103.3 
|Unallocated corporate overhead and other costs                         |  |                        | (57.9) |      |   | (37.3)
|Restructuring expenses                                                 |  |                        | (4.3)  |      |   | (16.6)
|Acquisition related costs for Clinical Diagnostics                     |  |                        | (13.9) |      |   | (9.8) 
|Olympus intangibles asset amortization related to Clinical Diagnostics |  |                        | (5.5)  |      |   |      
|                                                                       |  |                        |        |      |   |       
|Total operating income                                                 |  |                        | 79.9   |      |   | 39.6  
|                                                                       |  |                        |        |      |   |       
|                                                                       |  |                       
|Non-operating (income) expense:                                        |  |                        |        |      |   |       
|Interest income                                                        |  |                        | (1.3)  |      |   | (1.3) 
|Interest expense                                                       |  |                        | 24.1   |      |   | 10.9  
|Other                                                                  |  |                        | (0.3)  |      |   | 11.8  
|                                                                       |  |                        |        |      |   |       
|Total non-operating expense                                            |  |                        | 22.5   |      |   | 21.4  
|                                                                       |  |                        |        |      |   |       
|Earnings before income taxes                                           |  | $                      | 57.4   |      | $ | 18.2  
|                                                                       |  |                        |        |      |   |       



| | * | Amounts may not foot due to rounding
| | - | ------------------------------------

The increase in operating income generated from the Clinical Diagnostics segment is primarily due to higher revenue derived from the
Olympus acquisition coupled with strong recurring revenue growth, which generates a higher profit margin than cash instrument sales.

The increase in operating income for our Life Science segment during the quarter ended March 31, 2010 was primarily due to a 12.4%
constant currency increase in hardware placements coupled with improved profitability on product sales.



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##### Table of Contents

Non-Operating (Income) Expense



|                                     |  |                         |       |      |   |               |  |          
|------------------------------------ |  | ----------------------- | ----- | ---- | - | ------------- |  | ---------
|                                     |  | Quarter Ended March 31,
|                                     |  | 2010                    |       | 2009 |   | PercentChange
|(in millions)                        |  |                         |       |      |   |               |  |          
|Interest income                      |  | $                       | (1.3) |      | $ | (1.3)         |  |         
|Interest expense                     |  |                         | 24.1  |      |   | 10.9          |  | >100.0%  
|Other non-operating expense (income) |  |                         | (0.3) |      |   | 11.8          |  | >(100.0)%

Interest income was flat during the first quarter of 2010.

Interest expense increased by $13.2 million during the quarter ended March 31, 2010, due primarily to additional interest expense of
$8.2 million resulting from our issuance of $500 million of debt in May 2009 to finance the Olympus acquisition as well as higher interest expense on our income tax liabilities.

Other non-operating expense decreased by $12.1 million over the prior year quarter. This was primarily related to an $11.8 million
hedging loss in the first quarter of 2009 associated with forward contracts to purchase Japanese yen to mitigate the risk associated with changes in the value of the yen since our purchase price for the Olympus acquisition was paid in yen.

Income Tax

At the end of each interim reporting period, an estimate is made of the effective income tax rate expected to be applicable for the full
year. The effective income tax rate determined is used to provide for income taxes on a year-to-date basis. The tax effect of any tax law changes and certain other discrete events are reflected in the period in which they occur.

The effective tax rate for the quarters ended March 31, 2010 and 2009 was 32.6% and a tax benefit of 13.2%, respectively. The
difference in tax rates is primarily attributable to a reduction of a deferred tax asset in the first quarter 2010 related to Medicare drug subsidies, as described below, as well as favorable settlements of tax audits in the first quarter of 2009.

Our effective tax rate for the full year 2010 could be impacted by a number of factors such as new tax laws, interpretations
of existing tax laws, rulings by and settlements with taxing authorities, expiration of the statute of limitations for open years, our use of tax credits and our geographic profit mix. We expect our effective tax rate for the year to be
approximately 27% compared to 20.2% for 2009. The increase in tax rate is primarily attributable to (i) a write off in 2010 of an $8.0 million deferred tax asset as a result of the enactment in the United States of the Patient Protection and
Affordable Care Act and the Health Care and Education Reconciliation Act of 2010 which eliminated the Federal income tax deduction for a portion of prescription drug benefits which are offset by a subsidy under Medicare Part D and (ii) a shift
in geographic mix, with more income in 2010 in higher-tax rate countries as a result of lower costs in 2010 related to the ODS acquisition as compared to 2009. The tax rate for 2009 was also more favorably impacted by more tax audit settlements than
in 2010. The estimated effective tax rate for 2010 does not consider R&E tax credits in the United States as the credit provisions expired at the end of 2009. As of March 31, 2010 the credit has not been extended by the U.S. Congress.
Should Congress extend the R&E credit, as well as other expired tax provisions, for the tax year 2010, we expect our effective tax rate would be reduced by approximately one percentage point.

During the first quarter of 2009, we filed certain tax accounting method changes with the U.S. Internal Revenue Service
(IRS). As a result of these accounting method changes, certain tax deductions were accelerated and reflected in the 2008 federal income tax return, resulting in a net operating loss for that year for tax purposes. This loss has been
carried back to the 2006 tax year, which reduced taxes previously paid by $66.0 million. The acceleration of these tax deductions reduced certain permanent tax benefits totaling $3.4 million which increased tax expense in 2009.

Supplemental Information

Non-GAAP
Measures

Throughout this section, references are made to the following financial measures: constant
currency, adjusted operating income, adjusted operating margin, adjusted diluted earnings per share, adjusted earnings before interest, taxes, depreciation and amortization (adjusted
EBITDA), adjusted tax rate, free cash flow. These financial measures are an alternative presentation of our past and potential future operational performance and do not replace the presentation of the Companys
reported financial results under U.S. GAAP. We have provided these supplemental non-GAAP financial measures because they provide



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meaningful information regarding our results on a consistent and comparable basis for the periods presented. We use these non-GAAP financial measures for reviewing the operating results of our
business segments, for analyzing potential future business trends in connection with our budget process and base certain annual bonus plans on these non-GAAP financial measures. In order to measure our sales performance on a constant currency basis,
it is necessary to remove the impact of changes in foreign currency exchange rates which affects the comparability and trend of sales. Constant currency results are calculated by translating current year results at prior year foreign currency
exchange rates for the period, computed monthly. In addition, we believe investors will utilize this information to evaluate period-to-period results on a comparable basis and to better understand potential future operating results. The Company
encourages investors and other users of these financial statements to review its Consolidated Financial Statements and other publicly filed reports in their entirety and not to rely solely on any single financial measure. Non-GAAP financial measures
should be considered in addition to, but not as a substitute for or superior to, other measures of financial performance prepared in accordance with GAAP.

Adjusted operating income excludes the impact of income and expense such as charges associated with restructuring or relocations in
connection with our supply chain improvement initiatives, acquisition and integration related expenses, license fees, amortization of intangible assets acquired from Olympus and other income and expense items. Management uses adjusted operating
income to prepare operating budgets and forecasts to measure against our performance and to evaluate management performance for compensation purposes.

Adjusted operating margin is calculated using adjusted operating income, as described above, divided by revenue. Management uses adjusted
operating margin in its analysis of operating budgets and forecasts since this measure is reflective of our operating costs on an ongoing basis and excludes transactions or events that may be beyond the control of management or which are
unpredictable. Management uses adjusted operating margin when evaluating the performance trends of our Company compared to others.

A reconciliation of operating income and operating margin, the GAAP measures most directly comparable to adjusted operating income and
adjusted operating margin, are provided below.



|                                            |  |                         |       |      |   |     
|------------------------------------------- |  | ----------------------- | ----- | ---- | - | ----
|                                            |  | Quarter Ended March 31,
|                                            |  | 2010                    |       | 2009
|(in millions)                               |  |                         |       |      |   |     
|                                            |  |                        
|GAAP operating income                       |  | $                       | 79.9  |      | $ | 39.6
|Restructuring and acquisition related costs |  |                         | 18.2  |      |   | 26.4
|Olympus intangible asset amortization       |  |                         | 5.5   |      |   |    
|                                            |  |                         |       |      |   |     
|                                            |  |                        
|Adjusted operating income                   |  | $                       | 103.6 |      | $ | 66.0
|                                            |  |                         |       |      |   |     
|                                            |  |                        
|GAAP operating margin                       |  |                         | 9.1%  |      |   | 5.7%
|                                            |  |                        
|Impact of adjustments                       |  |                         | 2.7%  |      |   | 3.8%
|                                            |  |                         |       |      |   |     
|                                            |  |                        
|Adjusted operating margin                   |  |                         | 11.8% |      |   | 9.5%
|                                            |  |                         |       |      |   |     



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##### Table of Contents

Adjusted diluted earnings and earnings per share excludes the impact of charges to operating
expense as described above. Reconciliations of net earnings per share, the GAAP measure most directly comparable to adjusted earnings per share, are provided below.



|                                                     |  |        |       |                         |   |        |  |                   |        |  |   |       
|---------------------------------------------------- |  | ------ | ----- | ----------------------- | - | ------ |  | ----------------- | ------ |  | - | ------
|                                                     |  |        |       | Quarter Ended March 31, |   |       
|                                                     |  | 2010   |       | 2009                   
|                                                     |  | Amount |       | Per Diluted Share       |   | Amount |  | Per Diluted Share
|(in millions, except amounts per share)              |  |        |       |                         |   |        |  |                   |        |  |   |       
|                                                     |  |        |       |                        
|GAAP net earnings                                    |  | $      | 38.7  |                         | $ | 0.54   |  | $                 | 20.6   |  | $ | 0.32  
|Restructuring and acquisition related costs          |  |        | 18.2  |                         |   | 0.25   |  |                   | 26.4   |  |   | 0.41  
|Olympus intangible asset amortization                |  |        | 5.5   |                         |   | 0.08   |  |                   |       |  |   |      
|Foreign currency loss related to Olympus acquisition |  |        |      |                         |   |       |  |                   | 11.8   |  |   | 0.18  
|                                                     |  |        |       |                        
|Adjustment for income taxes                          |  |        | (8.6) |                         |   | (0.12) |  |                   | (13.3) |  |   | (0.20)
|                                                     |  |        |       |                        
|Deferred income tax write-off                        |  |        | 8.0   |                         |   | 0.11   |  |                   |       |  |   |      
|                                                     |  |        |       |                         |   |        |  |                   |        |  |   |       
|                                                     |  |        |       |                        
|Adjusted net earnings                                |  | $      | 61.8  |                         | $ | 0.86   |  | $                 | 45.5   |  | $ | 0.71  
|                                                     |  |        |       |                         |   |        |  |                   |        |  |   |       

Adjusted EBITDA is a non-GAAP measure that management
believes provides useful supplemental information for management and investors. Adjusted EBITDA is a tool that provides a measure of the adjusted net earnings, as described above, of the business before considering the impact of interest, taxes,
depreciation and amortization. We believe adjusted EBITDA provides management with a means to analyze and evaluate the profitability of our business and its ability to generate cash flow before the effect of interest, taxes, depreciation and
amortization. As is the case with all non-GAAP measures, investors should consider the limitations associated with this metric, including the potential lack of comparability of this measure from one company to another, and should recognize that
adjusted EBITDA does not provide a complete measure of our operating performance because it excludes many items that are included in our consolidated financial statements. Accordingly, investors are encouraged to use GAAP measures when evaluating
our financial performance.

A reconciliation of net earnings, the GAAP measure most directly comparable to adjusted EBITDA, is
provided below.



|                                                     |  |                         |       |      |   |      
|---------------------------------------------------- |  | ----------------------- | ----- | ---- | - | -----
|                                                     |  | Quarter Ended March 31,
|                                                     |  | 2010                    |       | 2009
|(in millions)                                        |  |                         |       |      |   |      
|                                                     |  |                        
|GAAP net earnings                                    |  | $                       | 38.7  |      | $ | 20.6 
|Income taxes                                         |  |                         | 18.7  |      |   | (2.4)
|Interest expense                                     |  |                         | 24.1  |      |   | 10.9 
|Depreciation and amortization                        |  |                         | 89.1  |      |   | 67.5 
|                                                     |  |                         |       |      |   |      
|                                                     |  |                        
|EBITDA                                               |  |                         | 170.6 |      |   | 96.6 
|                                                     |  |                        
|Reconciling items:                                   |  |                         |       |      |   |      
|                                                     |  |                        
|Restructuring and acquisition related costs          |  |                         | 18.2  |      |   | 26.4 
|Foreign currency loss related to Olympus acquisition |  |                         |      |      |   | 11.8 
|                                                     |  |                         |       |      |   |      
|                                                     |  |                        
|Adjusted EBITDA                                      |  | $                       | 188.8 |      | $ | 134.8
|                                                     |  |                         |       |      |   |      

Adjusted tax rate excludes the incremental tax effect
of income and expense items excluded from adjusted net earnings, as described above. A reconciliation of the tax rate, the GAAP measure most directly comparable to adjusted tax rate, is provided below



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|                                                     |  |                         |  |        
|---------------------------------------------------- |  | ----------------------- |  | -------
|                                                     |  | Quarter Ended March 31,
|                                                     |  | 2010                    |  | 2009   
|(in millions)                                        |  |                         |  |        
|                                                     |  |                        
|GAAP tax rate                                        |  | 32.6%                   |  | (13.2)%
|Reconciling items:                                   |  |                         |  |        
|Restructuring and acquisition related costs          |  | 4.0%                    |  | 23.2%  
|Olympus intangible asset amortization                |  | 1.1%                    |  |       
|Foreign currency loss related to Olympus acquisition |  |                        |  | 9.3%   
|Deferred tax asset write-off                         |  | (13.9)%                 |  |       
|                                                     |  |                         |  |        
|Adjusted tax rate                                    |  | 23.8%                   |  | 19.3%  
|                                                     |  |                         |  |        

Free cash flow is a non-GAAP measure that management
believes provides useful supplemental information for management and investors, because it reports the cash provided by operating activities after cash invested in property, plant and equipment. We believe this measure provides management and
investors with a measure to determine the health of the business and cash flow generated by the business in excess of the cash needed to be reinvested in the business. We provide this financial measure as a supplement to GAAP information to assist
ourselves and investors in understanding the impact of various items on our cash flows. A reconciliation of cash provided by operating activities, the GAAP measure most directly comparable to free cash flow, is provided below.



|                                           |  |                         |        |      |   |       
|------------------------------------------ |  | ----------------------- | ------ | ---- | - | ------
|                                           |  | Quarter Ended March 31,
|                                           |  | 2010                    |        | 2009
|(in millions)                              |  |                         |        |      |   |       
|                                           |  |                        
|Net cash provided by operating activities  |  | $                       | 98.2   |      | $ | 105.7 
|Additions to property, plant and equipment |  |                         | (34.3) |      |   | (30.9)
|Additions to customer leased instruments   |  |                         | (36.9) |      |   | (29.6)
|                                           |  |                         |        |      |   |       
|                                           |  |                        
|Free cash flow                             |  | $                       | 27.0   |      | $ | 45.2  
|                                           |  |                         |        |      |   |       

Net cash provided by operating activities for the
quarter ended March 31, 2010 includes a pension contribution of $20.0 million. No pension contribution was made during the prior year quarter.



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Liquidity and Capital Resources

Liquidity is our ability to generate sufficient cash flows from operating activities to meet our obligations and commitments. In addition,
liquidity includes the ability to obtain appropriate financing and to convert those assets that are no longer required in meeting existing strategic and financing objectives into cash. Therefore, for purposes of achieving long-range business
objectives and meeting our commitments, liquidity cannot be considered separately from capital resources that consist of current and potentially available funds.

Our business model, in particular recurring revenue comprised of consumable supplies (including reagent test kits), service, and OTL
payments, allows us to generate substantial operating cash flows. We continue to invest a substantial portion of this cash flow in instruments leased to customers. We expect operating cash flows to increase as our revenue and depreciation from new
OTLs increase year over year. We anticipate our operating cash flows together with the funds available through our credit facilities will continue to satisfy our working capital requirements. During the next twelve months, we anticipate using our
operating cash flows or other sources of liquidity to:



| |  |  | Facilitate growth in the business by developing, marketing and launching new products. We expect new product offerings to come from new technologies
gained through licensing arrangements, existing R&D projects, and business acquisitions,
| | - |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Maintain or raise our quarterly dividend. In April 2010, our Board of Directors declared a quarterly cash dividend of $0.18 per share, payable on
May 21, 2010 to stockholders of record on May 7, 2010.
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Pay costs associated with our supply chain and restructuring initiatives,
| | - |  | -------------------------------------------------------------------------



| |  |  | Complete our Orange County consolidation project,
| | - |  | -------------------------------------------------



| |  |  | Make pension and postretirement plan contributions, and
| | - |  | -------------------------------------------------------



| |  |  | Repurchase our common shares
| | - |  | ----------------------------

We expect payments associated with the environmental clean up of our Fullerton facility to become more significant in 2010 and beyond.
Proceeds from the potential sale of the Fullerton facility are not anticipated in the near term.

In November 2001, we issued
$235.0 million of 6.875% unsecured Senior Notes due November 15, 2011. We expect to retire these Notes with available cash in 2011.

Following is a summary of our cash flow from operating, investing and financing activities, as reflected in our Condensed Consolidated
Statements of Cash Flows (in millions):



|                                                      |  |                        |        |      |   |       
|----------------------------------------------------- |  | ---------------------- | ------ | ---- | - | ------
|                                                      |  | QuarterEnded March 31,
|                                                      |  | 2010                   |        | 2009
|Cash provided by (used in):                           |  |                        |        |      |   |       
|Operating activities                                  |  | $                      | 98.2   |      | $ | 105.7 
|Investing activities                                  |  |                        | (88.8) |      |   | (60.5)
|Financing activities                                  |  |                        | 3.1    |      |   | (7.3) 
|Effect of exchange rates on cash and cash equivalents |  |                        | (4.8)  |      |   | (10.2)
|                                                      |  |                        |        |      |   |       
|Change in cash and cash equivalents                   |  | $                      | 7.7    |      | $ | 27.7  
|                                                      |  |                        |        |      |   |       

Cash provided by operating activities for the first
quarter of 2010 decreased by $7.5 million due primarily to the pension contribution of $20.0 million made in 2010, partially offset by an increase in net earnings. Investing activities used cash of $88.8 million in the first quarter of 2010,
compared to $60.5 million in the same period in 2009, an increase of $28.3 million. The increase in cash used for investing activities is due to the purchase of short term investments and new customer lease instruments and payments for technology
licenses.



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Cash flows provided by financing activities increased by $10.4 million compared to the same
period in the prior year due primarily to an increase in proceeds from issuance of stock, partially offset by an increase in the repurchase of common stock.

Financing Arrangements

At March 31, 2010 approximately $206.2 million of unused, uncommitted, short-term lines of credit were available to our subsidiaries
outside the U.S. at various interest rates. In the U.S., $40.0 million in unused, uncommitted, short-term lines of credit at prevailing market rates were available, excluding the accounts receivable securitization program described below.

Our wholly owned subsidiary, Beckman Coulter Finance Company, LLC (BCFC), a Delaware limited liability company,
entered into an accounts receivable securitization program with several financial institutions. The securitization facility is on a 364-day revolving basis. As part of the securitization program, we transferred our interest in a defined pool of
accounts receivable to BCFC. In turn, BCFC sold an ownership interest in the underlying receivables to multi-seller conduits administered by a third party bank. The sale of receivables under the program is accounted for as a secured borrowing. The
cost of funds under this program varies based on changes in interest rates. The term of the agreement extends to October 27, 2010 and the maximum borrowing amount is $125.0 million. We did not have any amounts drawn on the facility as of
March 31, 2010.

In May 2009, we entered into an Amended and Restated Credit Agreement (the Credit Facility)
and extended the maturity date of the Credit Facility to May 2012. The Credit Facility provides us with a $350.0 million revolving line of credit, which may be increased in $50.0 million increments up to a maximum line of credit of $450.0 million.
Interest on advances is determined using formulas specified in the agreement, generally, an approximation of LIBOR plus 2.25% to 2.875% margin with the precise margin determinable based on our long-term senior unsecured non-credit-enhanced debt
rating, which as of March 31, 2010 was 0.25%. We also must pay a facility fee of 0.50% per annum on the aggregate average daily amount of each lenders commitment with the precise margin determinable based on our long-term senior
unsecured non-credit-enhanced debt rating, which as of March 31, 2010 was a S&P rating of BBB. At March 31, 2010, no amounts were outstanding under the Credit Facility.

Recent Accounting Developments

See Note 1, Nature of Business and Summary of Significant Accounting Policies, of the Notes to the Condensed
Consolidated Financial Statements in this filing for a description of recently adopted accounting pronouncements

Other Events



|Item 3. | Quantitative and Qualitative Disclosures About Market Risk
|------- | ----------------------------------------------------------

For information regarding our exposure to certain market risks, see Item 7A Quantitative and Qualitative Disclosures About
Market Risk in our Annual Report on Form 10-K for the fiscal year ended December 31, 2009. Except as noted below, there have been no significant changes in our market risk exposures from the amounts and descriptions disclosed
therein.

We have significant foreign currency exposures related to the Euro, Japanese yen, Australian dollar, British
Pound Sterling and Canadian dollar. As of March 31, 2010 and December 31, 2009, the notional amounts of all derivative foreign exchange contracts were $517.3 million and $546.3 million, respectively. Notional amounts are stated
in U.S. dollar equivalents at the spot exchange rate at the respective dates. The net fair values of all derivative foreign exchange contracts as of March 31, 2010 and December 31, 2009 resulted in the recognition of net assets of $8.7
million and $1.9 million, respectively. We estimated the sensitivity of the fair value of all derivative foreign exchange contracts to a hypothetical 10% strengthening and 10% weakening of the spot exchange rates for the U.S. dollar against the
foreign currencies at March 31, 2010. The analysis showed that a 10% strengthening of the U.S. dollar would result in a gain from a fair value change of $19.5 million and a 10% weakening of the U.S. dollar would result in a loss from a fair
value change of $16.6 million in these instruments. Losses and gains on the underlying hedged transactions would largely offset any gains and losses on the fair value of the derivative contracts. These offsetting gains and losses are not reflected
in the above analysis. Significant foreign currency exposures at March 31, 2010 were not materially different than those at December 31, 2009.

Similarly, we performed a sensitivity analysis on our variable rate debt instruments. A one percentage point increase or decrease in
interest rates was estimated to decrease or increase this years pre-tax earnings by $0.1 million based on the amount of variable rate debt outstanding at March 31, 2010.

Additional information with respect to our foreign currency and interest rate exposures is discussed in Note 4,
Derivativesand Note 5, Fair Value Measurements of the Notes to Condensed Consolidated Financial Statements included in Part I Financial Information, Item 1 Financial Statements of
this filing.



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|Item 4. | Controls and Procedures
|------- | -----------------------

Disclosure
Controls and Procedures.

Under the supervision and with the participation of our management,
including our Chief Executive Officer and our Chief Financial Officer, we carried out an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures pursuant to Rule 13a-15(b) under the Securities Act of
1934, as amended, as of the end of the period covered by this report. Based on the foregoing, our Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures were effective as of the end of the period
covered by this report, at the reasonable level of assurance.

Changes in Internal Control Over Financial Reporting.

Under the supervision and with the participation of our management, including our Chief Executive Officer
and our Chief Financial Officer, we conducted an evaluation of any changes in internal control over financial reporting (as such term is defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) that occurred during our most recently
completed fiscal quarter. Based on that evaluation, our Chief Executive Officer and our Chief Financial Officer concluded that there has not been any change in our internal control over financial reporting during that quarter that has materially
affected, or is reasonably likely to materially affect, our internal control over financial reporting.

PART
IIOTHER INFORMATION



|Item 1A. | Risk Factors
|-------- | ------------

We face significant
competition, and our failure to compete effectively could adversely affect our sales and results of operations.

We face
significant competition from many domestic and international manufacturers, with many of these companies participating in one or more parts of each of our markets. Some of these competitors are divisions or subsidiaries of corporations with
substantial resources. We also compete with several companies that offer reagents, supplies and service for laboratory instruments that are manufactured by us or others. Our sales and results of operations may be adversely affected by loss of market
share through aggressive competition, the rate at which new products are introduced by us and our competitors and the extent to which new products displace existing technologies and competitive pricing especially in areas where currency has an
effect.

We are subject to various federal, state, local and foreign regulations, and compliance with these laws or any new laws or
regulations could cause us to incur substantial costs and adversely affect our business and results of operations.

Our
products and operations are subject to a number of federal, state, local and foreign laws and regulations. A determination that our products or operations are not in compliance with these laws and regulations could subject us to civil and criminal
penalties, prevent us from manufacturing or selling certain of our products and cause us to incur substantial costs in order to be in compliance. To varying degrees, compliance with these laws and regulations may:



| |  |  | Take a significant amount of time
| | - |  | ---------------------------------



| |  |  | Require the expenditure of substantial resources
| | - |  | ------------------------------------------------



| |  |  | Involve extensive clinical and pre-clinical testing
| | - |  | ---------------------------------------------------



| |  |  | Involve modifications, repairs or replacements of our products
| | - |  | --------------------------------------------------------------



| |  |  | Result in limitations on the proposed uses of our products
| | - |  | ----------------------------------------------------------

Our compliance costs include addressing our ongoing responsibilities under FDA regulations that apply to our products both before and
after they are approved for distribution. If FDA were to conclude that any of our products are ineffective or pose an unreasonable health risk, or that we are not in compliance with applicable regulations, FDA could:



| |  |  | Ban the product
| | - |  | ---------------



| |  |  | Seize adulterated or misbranded products
| | - |  | ----------------------------------------



| |  |  | Order a recall, repair or replacement of such product or a refund to the purchaser of the product
| | - |  | -------------------------------------------------------------------------------------------------



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| |  |  | Require us to notify health professionals and others that the products present unreasonable risks of substantial harm to the public health
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Impose operating restrictions
| | - |  | -----------------------------



| |  |  | Enjoin and restrain certain violations of applicable law pertaining to the products
| | - |  | -----------------------------------------------------------------------------------



| |  |  | Assess civil penalties against our company, officers or employees
| | - |  | -----------------------------------------------------------------



| |  |  | Recommend criminal prosecution to the Department of Justice
| | - |  | -----------------------------------------------------------

On April 12, 2010, we announced that we had issued a notice to our U.S. customers who use our
AccuTnI troponin test kits on our UniCel DxI Immunoassay system that we are removing the AccuTnI assay from use with the DxI system as of May 31, 2010. On April 28, 2010, we announced that FDA classified our troponin recall as a Class
II event and agreed to give customers an extension to August 1, 2010 to switch from running troponin on DxI systems to an alternate method. FDA has indicated to us that it believes certain modifications to our troponin test kits, as used on our
DxI systems as well as on our Access systems, were made without obtaining appropriate product clearances from the agency. We are in discussions with FDA regarding the 510(k) clearance process for our troponin test kits for both the DxI and Access
immunoassay systems and cannot provide any assurances on when we will be able to return troponin to the DxI. For U.S. labs that are not currently using Access systems to perform troponin testing, it is unlikely that we will be able to
provide troponin test kits for use on Access analyzers until we obtain 510(k) clearance and there can be no assurance that FDA will continue to permit us to provide troponin test kits with appropriate additional notices and precautions to
U.S. customers who currently use Access systems for troponin testing. We are continuing to work to resolve these matters with FDA but can provide no assurances regarding when 510(k) clearance will be obtained. The process for new 510(k)
clearances for our products could be lengthy and costly and may require the withdrawal of product from the market until such clearances are obtained as well as the imposition of recalls or the initiation of enforcement actions against us by FDA,
including warning letters, fines, seizures, consent orders or injunctions. The loss of revenue from our products that are the subject of FDA inquiries could be more than we estimate and our foreign sales could also be adversely affected. These
issues could cause us to lose customers and there could be unanticipated costs associated with these matters or other discussions with FDA.

Given the issues pertaining to our troponin test kits as well as our recent recall relating to sodium testing on our DxC chemistry
systems, we are currently evaluating our internal processes and procedures regarding our product, quality and regulatory systems. It is possible that more of our products could be affected and the actions with respect to those products could
adversely affect our business and operating results. Our internal review of our products could reveal failures in our processes and systems which could be significant.

Foreign governmental regulations have become more common and stringent. We may become subject to more rigorous regulation by foreign
governmental authorities in the future. Penalties for noncompliance with foreign regulation could be severe, including revocation or suspension of the ability to sell products in that country and criminal sanctions. An adverse regulatory action in
the U.S. or in other countries could restrict us from effectively marketing and selling our products.

Current and future healthcare reform
changes may have a material adverse effect on our operating results.

Changes to existing laws or regulations, including
the effect of potential health care reforms, also could prevent us from manufacturing or selling our products, reduce funding for government and academic research and cause us to incur substantial compliance costs.

The recently enacted Patient Protection and Affordable Care Act, as amended by the Health Care and Education Affordability Reconciliation
Act (collectively, the PPACA), institutes substantial changes to the way health care is financed by both governmental and private insurers and contains several provisions that could have a material impact on our business. With limited
exceptions, the PPACA, among other things, imposes a 2.3% deductible excise tax on any entity that manufactures or imports medical devices offered for sale in the United States beginning in 2013. The PPACA also imposes new reporting and disclosure
requirements on device manufacturers for any transfer of value made or distributed to prescribers and other healthcare providers, effective March 30, 2013. Such information will be made publicly available in a searchable format
beginning September 30, 2013. In addition, device manufacturers will also be required to report and disclose any investment interests held by physicians and their immediate family members during the preceding calendar year. Failure to submit
required information may result in civil monetary penalties of up to an aggregate of $150,000 per year (and up to an aggregate of $1 million per year for knowing failures), for all payments, transfers of value or ownership or investment
interests not reported in an annual submission. We cannot predict at this time the full impact of the PPACA on our business. Nor can we predict whether or the extent to which other proposed changes will be adopted, if any, or how these or
future changes will affect the demand for our services. The PPACA as well as other health care reform measures that may be adopted in the future could have a material adverse effect on us and our industry.



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We must continue to market and improve the quality of our existing products and develop new products that
meet customer needs and expectations or our business and results of operations will be adversely impacted.

Our ability to
continue to grow depends on our success in continuing to market and improve the quality of our existing products and develop new products that meet customer needs and expectations. Improving existing products and developing new products requires us
to successfully integrate hardware, software and chemistry components. Consequently, the expected introductions of new products may be impacted by factors such as complexity and uncertainty in the development of new high-technology products and
availability of qualified engineers, programmers and other key personnel. The viability of supply partners also may impact new product introductions for products we distribute. In addition, our ability to introduce new products and to continue
marketing existing products may be affected by patents and other intellectual property rights of others, our ability to protect our intellectual property from others, the acquisition and integration of other companies and intellectual property and
our ability to obtain regulatory approvals, including delays in obtaining any government marketing authorizations necessary to market the products, particularly with respect to Clinical Diagnostics products. Factors affecting the introduction of
molecular diagnostic products include the inability to develop clinical diagnostic tests based on new technologies, a determination that the tests do not provide sufficient precision and accuracy, identification of additional necessary intellectual
property rights, failure to establish the clinical utility of these tests during clinical studies and delays resulting from the timing and scope of regulatory agency reviews.

We are subject to laws targeting fraud and abuse in the healthcare industry and if we are subject to scrutiny under these laws we could incur
significant costs.

We are subject to various federal, state and local laws targeting fraud and abuse in the healthcare
industry, including anti-kickback and false claims laws. The Federal Anti-Kickback Statute prohibits persons from knowingly and willfully soliciting, offering, receiving or providing remuneration, directly or indirectly, in exchange for or to induce
either the referral of an individual, or the furnishing or arranging for a good or service, for which payment may be made under a federal health care program, such as Medicare or Medicaid. The definition of remuneration has been broadly
interpreted to include anything of value, including, for example, gifts, discounts, the furnishing of free supplies, equipment or services, credit arrangements, payments of cash and waivers of payment. The recently enacted PPACA, among other things,
amends the intent requirement of the federal anti-kickback and criminal health care fraud statutes. A person or entity no longer needs to have actual knowledge of this statute or specific intent to violate it. In addition, the PPACA provides that
the government may assert that a claim including items or services resulting from a violation of the federal anti-kickback statute constitutes a false or fraudulent claim for purposes of the false claims statutes. Although there are a number of
statutory exemptions and regulatory safe harbors protecting certain common activities from prosecution, the exemptions and safe harbors are drawn narrowly, and practices that involve remuneration could be subject to scrutiny if they do not qualify
for an exemption or safe harbor. Many states have also adopted laws similar to the Anti-Kickback Statute. Some of these state prohibitions apply to referral of patients for health care items or services reimbursed by any payor, not only the Medicare
and Medicaid programs, and do not contain identical safe harbors.

The Health Insurance Portability and Accountability Act of
1996 also created two new federal crimes: health care fraud and false statements relating to health care matters. The health care fraud statute prohibits knowingly and willfully executing a scheme to defraud any health care benefit program,
including private payors. The false statements statute prohibits knowingly and willfully falsifying, concealing or covering up a material fact or making any materially false, fictitious or fraudulent statement in connection with the delivery of or
payment for health care benefits, items or services.

Another development affecting the health care industry is the increased
use of the federal civil False Claims Act and, in particular, actions brought pursuant to the False Claims Acts whistleblower or qui tam provisions. The False Claims Act imposes liability on any person or entity who,
among other things, knowingly presents, or causes to be presented, a false or fraudulent claim for payment by a federal health care program. The qui tam provisions of the False Claims Act allow a private individual to bring actions on behalf of the
federal government alleging that the defendant has submitted a false claim to the federal government, and to share in any monetary recovery. In addition, various states have enacted false claim laws analogous to the False Claims Act. Our future
activities relating to the sale and marketing of our products may be subject to scrutiny under these laws. We are unable to predict whether we would be subject to actions under the False Claims Act or a similar state law, or the impact of such
actions. However, the costs of defending any such claims, as well as any sanctions imposed, could significantly adversely affect our results of operations.



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Our business could be adversely affected if we do not prevail in present or future third party
intellectual property litigation adverse to our products or if our patents or other intellectual property rights are challenged, invalidated, circumvented or expire.

We cannot assure you that our products will be free of intellectual property rights of others or that a court will not find such products
to infringe third party rights. Patent disputes are frequent, costly and may preclude or delay product commercialization. We may have to pay significant licensing fees to obtain access to third party intellectual property rights to make and sell
current products or to introduce new products and cannot guarantee that such licenses will be available on terms acceptable to us, or at all. We also cannot assure you that our issued patents will include claims sufficiently broad to prevent
competitors from developing competing products or that pending patent applications will result in issued patents. Obtaining and maintaining patents is an iterative process with patent offices worldwide. Our patents may not protect us against
competitors with similar products or technologies, because competing products or technologies may not infringe our patents. The enforcement of our issued patents requires the filing and prosecution of legal actions in countries around the world, and
we cannot assure you that we will prevail in such actions.

We rely on certain suppliers and manufacturers for raw materials and other
products, and fluctuations in the availability and price of such products and services may interfere with our ability to meet our customers needs.

Difficulty in obtaining raw materials and components for our products, especially in the rapidly evolving electronic components market,
could affect our ability to achieve anticipated production levels. For some of our products we are dependent on a small number of suppliers of finished products and of critical raw materials and components and our ability to obtain, enter into and
maintain contracts with these suppliers. We cannot assure you that we will be able to obtain, enter into or maintain all such contracts in the future. On occasion, we have been forced to redesign portions of products when a supplier of critical raw
materials or components terminated its contract or no longer made the materials or components available. If we are unable to achieve anticipated production levels and meet our customers needs, our operating results could be adversely affected. In
addition, our results of operations may be significantly impacted by unanticipated increases in the costs of labor, raw materials, freight, utilities and other items needed to develop, manufacture and maintain our products and operate our business.
Suppliers also may deliver components or materials that do not meet specifications preventing us from manufacturing products that meet our design specifications or customer requirements.

Consolidation of our customer base and the formation of group purchasing organizations could adversely affect our sales and results of operations.

Consolidation among health care providers and the formation of buying groups has put pressure on pricing and sales of our
products, and in some instances, required payment of fees to group purchasing organizations. Our success in these areas depends partly on our ability to enter into contracts with integrated health networks and group purchasing organizations. If we
are unable to enter into contracts with these group purchasing organizations and integrated health networks on terms acceptable to us, our sales and results of operations may be adversely affected. Even if we are able to enter into these contracts,
they may be on terms that negatively affect our current or future profitability.

Reductions in government funding to our customers could
negatively impact our sales and results of operations.

Many of our customers rely on government funding and on prompt and
full reimbursement by Medicare and equivalent programs outside of the United States. In addition, our sales are affected by factors such as:



| |  |  | Level of government funding for clinical testing, biomedical research, bioterrorism, forensics, and food safety
| | - |  | ---------------------------------------------------------------------------------------------------------------



| |  |  | Pharmaceutical company spending policies
| | - |  | ----------------------------------------



| |  |  | Access to capital by biotechnology start ups
| | - |  | --------------------------------------------

A reduction in the amount or types of government funding or reimbursement that affect our customers, as well as the unavailability of
capital to our Clinical Diagnostics and biomedical research customers, could have a negative impact on our sales. Global economic uncertainty can result in lower levels of government funding or reimbursement.

Our international operations expose us to foreign currency exchange fluctuations.

We operate a substantial portion of our business outside of the United States and are therefore exposed to fluctuations in the exchange
rate between the U.S. dollar and the currencies in which our foreign subsidiaries and dealers receive revenue and pay expenses. With a strengthening U.S. dollar, this exposure includes a negative impact on margins on sales of our products in foreign
countries that are manufactured in the United States. We may enter into currency hedging arrangements in an effort to stabilize certain of these fluctuations. There are certain costs associated with these currency hedging arrangements, and we cannot
be certain that such arrangements will have the full intended effect. Our currency exposures may not be hedged exposing us to losses on our



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assets and cash flows denominated in these currencies. Our dealers may experience slower payment terms from their customers or have trouble paying for the purchases due to a stronger U.S. dollar.
Further, we are exposed to counter party risks in the event that our counterparties do not perform in accordance with the contract terms. The Olympus acquisition also exposes us to more risk related to variability in the Japanese Yen, because a
portion of our manufacturing and R&D costs are now centered in Japan.

Global market, economic and political conditions and natural
disasters may adversely affect our operations and performance.

Our operations and performance depend significantly on
worldwide market economic and political conditions and their impact on levels of certain customer spending, which may deteriorate significantly in many countries and regions, including the United States, particularly in light of the current
worldwide market disruptions and economic downturn, and may remain depressed for the foreseeable future. For example, global political conditions and general economic conditions in foreign countries where we do significant business, such as the
United States, France, Germany, India, Japan and China, could negatively impact on our sales. These disruptions could adversely affect our customers ability to pay for products or purchase additional products. These conditions also may
adversely affect our suppliers, which could cause disruptions in our ability to produce our products. In addition, economic and market volatility and disruption, such as the current worldwide market disruptions and economic downturn, may adversely
affect the cost and availability of credit. Concern about market stability and counterparty strength may lead lenders and institutional investors to reduce or cease to provide funding to borrowers. Natural disasters, such as hurricanes, earthquakes
and the recent volcano in Iceland, could adversely affect our customers and our ability to manufacture and deliver products. Any of these market, economic, political or natural disaster factors could have a material adverse effect on demand for our
products, our ability to manufacture, support and distribute products, our financial condition and operating results, and the terms of equity and debt capital and our ability to issue them.

Costs associated with our supply chain initiatives may disrupt operations and affect earnings and results of operations.

We have announced several relocation plans, including our plan to vacate our Fullerton, California facility and consolidate those
operations to other facilities. In connection with this consolidation and the related closure of our Fullerton, California site, we plan to relocate our data center in 2010. We also have initiated environmental studies of the Fullerton facility and
could incur substantial costs in addition to those already estimated and recorded depending upon determination of the remediation requirements. We may experience difficulties, delays or unexpected costs and not achieve anticipated cost savings from
our relocation and consolidation plans. The scope and timing of the relocations and related charges and savings could disrupt our operations and impact our earnings and results of operations.

We are subject to various income tax risks and regulations throughout the world.

By conducting business in the United States and many other countries, we must continually interpret, and then comply with, the income tax
rules and regulations in these countries. Different interpretations of income tax rules and regulations as applied to our facts by us and applicable tax authorities throughout the world could result, either historically or prospectively, in adverse
impacts to our worldwide effective income tax rates and income tax liabilities. Other factors that could impact our worldwide effective tax rates and income tax liabilities are:



| |  |  | Amount of taxable income in the various countries in which we conduct business
| | - |  | ------------------------------------------------------------------------------



| |  |  | Tax rates in those countries
| | - |  | ----------------------------



| |  |  | Income tax treaties between countries
| | - |  | -------------------------------------



| |  |  | Extent to which income is repatriated between countries
| | - |  | -------------------------------------------------------



| |  |  | Future changes in income tax rules and regulations
| | - |  | --------------------------------------------------



| |  |  | Adoption of new types of taxes such as consumption, sales and value added taxes
| | - |  | -------------------------------------------------------------------------------

Our investment in marketable securities is significant and is subject to market, interest rate and credit risk that may reduce its value.

Within the pension plan assets, we maintain a significant portfolio of marketable securities as well as other assets
subject to market fluctuations. Our earnings and stockholders equity could be adversely affected by changes in the value of this portfolio. In particular, the value of our investments may be adversely affected by general economic conditions,
changes in interest rates, downgrades in the corporate bonds included in the portfolio and other factors. Each of these events may cause us to reduce the carrying value of our investment portfolio and may result in higher pension expense or our
pension plans being further under-funded.



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Acquisitions and divestitures pose financial and other risks and challenges.

We routinely explore acquiring other businesses and assets that would fit strategically. From time to time, we also may consider disposing
of certain assets, subsidiaries or lines of business that are less of a strategic fit within our portfolio. Potential acquisitions or divestitures present financial, managerial and operational challenges, including diversion of management attention,
difficulty with integrating different corporate cultures or separating personnel and financial and other systems, increased expenses, assumption of unknown liabilities, indemnities and potential disputes with the buyers or sellers. There can be no
assurance that we will engage in any acquisitions or divestitures or that we will be able to do so on terms that will result in any expected benefits. Acquisitions financed with borrowings could put financial stress on our earnings resulting in
materially higher interest rates.

The Olympus acquisition involves the integration of Olympus with our existing Clinical
Diagnostics business. The integration of the two businesses that have previously operated separately is a costly and time-consuming process that involves a number of risks including:



| |  |  | Difficulties in assimilating different corporate cultures, practices and sales and distribution methodologies, as well as in assimilating and retaining
geographically dispersed operations and personnel
| | - |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Reliance on Olympus Corporation to provide certain transitional services, such as ongoing financial information and other data or support needed to
successfully operate the Olympus business until we have completed the integration for these services
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Larger foreign operations and increased exposure to risks relating to business operations outside the United States
| | - |  | -------------------------------------------------------------------------------------------------------------------



| |  |  | Difficulties and unanticipated expenses related to integrating facilities, departments, systems, including accounting systems, computer and other
technologies, books and records and procedures, as well as maintaining uniform standards, including internal accounting controls, procedures and policies
| | - |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Difficulties in implementing anticipated infrastructure changes, which could offset any such savings and other synergies resulting from the Olympus
acquisition
| | - |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Costs and expenses associated with any undisclosed or potential liabilities
| | - |  | ---------------------------------------------------------------------------



| |  |  | Use of cash resources and increased capital expenditures on integration and implementation activities in excess of our current expectations, which
could offset any such savings and other synergies resulting from the Olympus acquisition
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Even if we
successfully integrate the Olympus operations, we may be unable to realize our anticipated cost savings, synergies and growth from the integration in our expected time frame and the costs of achieving these benefits may be higher than expected.

The Olympus operations are subject to their own risks, which we may not be able to manage successfully. There may be additional risks
resulting from the Olympus acquisition that are not presently known to us which could adversely affect us.

The results of
Olympus operations are subject to many of the same risks that affect our financial condition and results of operations and, more specifically, those of our Clinical Diagnostics business. Any discovery of adverse information concerning Olympus after
the closing of the acquisition could be material and, in many cases, we would have limited rights of recovery. The indemnification provided in the master purchase agreement may be insufficient to protect or compensate us for all losses resulting
from the acquisition or Olympus prior operations. For example, under the terms of the master purchase agreement, indemnification is limited to certain subject matters and the maximum aggregate amount of such losses for which Olympus
Corporation will indemnify us is, subject to certain exceptions, limited to 12.5% of the purchase price of Olympus. A material loss associated with the Olympus acquisition for which there is not adequate indemnification could negatively affect our
results of operations, financial condition and industry reputation and reduce the anticipated benefits of the acquisition.



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|Item 2. | Unregistered Sales of Equity Securities and Use of Proceeds
|------- | -----------------------------------------------------------

ISSUER PURCHASES OF EQUITY SECURITIES



|                            |  |                               |  |                                     |       |                                                                              |         |                                                                             |          
|--------------------------- |  | ----------------------------- |  | ----------------------------------- | ----- | ---------------------------------------------------------------------------- | ------- | --------------------------------------------------------------------------- | ---------
|Period                      |  | TotalNumberof SharesPurchased |  | WeightedAverage PricePaid per Share |       | Total Number ofShares Purchased asPart of
PubliclyAnnouncedPlans or programs |         | Maximum Numberof Shares that MayYet Be PurchasedUnder the 
Plans orPrograms
|January 1 through 31, 2010  |  | 52,981                        |  | $                                   | 67.73 |                                                                              |        |                                                                             |         
|February 1 through 28, 2010 |  | 306,914                       |  |                                     | 65.67 |                                                                              | 224,440 |                                                                             | 1,275,560
|March 1 through 31, 2010    |  | 728                           |  |                                     | 68.67 |                                                                              |        |                                                                             | 1,275,560
|                            |  |                               |  |                                     |       |                                                                              |         |                                                                             |          
|Total                       |  | 360,623                       |  | $                                   | 65.98 |                                                                              | 224,440 |                                                                             | 1,275,560
|                            |  |                               |  |                                     |       |                                                                              |         |                                                                             |          

136,183 of the shares purchased are attributable to
shares surrendered to us by employees in payment of tax obligations related to the vesting of restricted stock.

In February
2010, the Companys Board of Directors authorized the repurchase of up to 1.5 million shares of common stock through 2010. 224,440 of the shares above were repurchased pursuant to this plan.



|Item 6. | Exhibits
|------- | --------

A list of
exhibits filed with this Form 10-Q is set forth in the Exhibit Index and is incorporated by reference.



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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.



|                  |  |                       |  |                                                                  
|----------------- |  | --------------------- |  | -----------------------------------------------------------------
|                  |  | BECKMAN COULTER, INC.
|                  |  | (Registrant)         
|                  |  |                      
|Date: May 5, 2010 |  | By                    |  | /s/Scott Garrett                                                 
|                  |  |                       |  | Scott Garrett                                                    
|                  |  |                       |  | Chairman of the Board, President
and Chief Executive Officer     
|                  |  |                      
|Date: May 5, 2010 |  | By                    |  | /s/Charles P. Slacik                                             
|                  |  |                       |  | Charles P. Slacik                                                
|                  |  |                       |  | Senior Vice President &
Chief Financial Officer                  
|                  |  |                      
|Date: May 5, 2010 |  | By                    |  | /s/Carolyn D. Beaver                                             
|                  |  |                       |  | Carolyn D. Beaver                                                
|                  |  |                       |  | Corporate Vice President, Controller and
Chief Accounting Officer



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INDEX TO EXHIBITS



|            |  |                                                                                                        
|----------- |  | -------------------------------------------------------------------------------------------------------
|Exhibit No. |  | Exhibit Description                                                                                    
|            | 
|15.1        |  | Report of Independent Registered Public Accounting Firm                                                
|            | 
|15.2        |  | Letter of Acknowledgement of Use of Report on Unaudited Interim Financial Information dated May 5, 2010
|            | 
|31          |  | Rule 13a-14(a)/15d-14(a) Certification                                                                 
|            | 
|32          |  | Section 1350 Certification                                                                             



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