# Patent

## Title
Natural liniment for treatment of skin cancers

## Abstract

A liniment composition for reversing or retarding the growth of cancerous skin tumors comprising primarily, pancreatin, pepsin, betaine HCL, emulsified vitamin A, and zinc, pancrelipase, fenugreek, papain, amylase and ox bile extract, with optional trace amounts of other ingredients.

## Background
FIELD OF THE INVENTION
This invention comprises a liniment composed of natural substances which can be applied to skin cancer tumors to shrink the tumors or retard their growth.
BACKGROUND OF THE INVENTION
According to the American Cancer Society, each year there are thousands of new cases of skin cancers. The most serious type of skin cancer, melanoma, was estimated to have 62,190 cases in 2006, resulting in 7910 deaths, due to melanoma.
There are more than one million cases of non-melanoma (such as basal cell or squamous cell) skin cancer cases diagnosed yearly in the United States.
There have been compositions of natural substances suggested, such as the combination of powdered bloodroot, powdered ginger root and zinc chloride, for treatment of skin lesions, U.S. Pat. No. 4,515,779 issued to Elliott on May 7, 1985.
SUMMARY OF THE INVENTION
The liniment of this invention comprises primarily, pancreatin, pepsin, betaine HCL, emulsified vitamin A, and zinc. Also present are pancrelipase, fenugreek, papain, amylase and ox bile extract. The vitamin A is emulsified in water or in a mixture of water and acacia with d-alpha tocopherol as an anti oxidant.
The pancreatin, pepsin, betaine HCL, pancrelipase, fenugreek, papain, amylase and ox bile extract, can be obtained from various suppliers or can be obtained in a dietary supplement called Digest-All, manufactured by Immuno Screen of St. Petersburg, Fla.
The emulsified Vitamin A in a mixture of water and acacia, with d-alpha tocopherol as an anti oxidant, may be obtained in a dietary supplement called Bio-Ae-Mulsion Forte, manufactured by Biotics Research Corporation of Rosenberg, Tex.
The zinc may come in the form of zinc citrate.
There optionally may be added to the composition trace amounts of apple cider vinegar and minced garlic clove.
The liniment is prepared by grinding the ingredients in a mortar and pestle at ambient temperature where it reaches a thick salve consistency.



BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a graph showing test treatments using the liniment of this invention.



DETAILED DESCRIPTION OF THE INVENTION
The amount of the ingredients in the liniment, by weight, are as follows:














Ingredient
By weight









pancreatin
10% to 20%



pepsin
 5% to 10%



betaine HCL
15% to 30%



emulsified vitamin A
 5% to 15%



zinc citrate
 5% to 10%



pancrelipase
10% to 20%



fenugreek
10% to 20%



papain
2% to 5%



amylase
2% to 5%



ox bile extract
 5% to 15%



apple cider vinegar
optional trace amounts



garlic clove
optional trace amounts










The basic ingredients may be present in approximately equal amounts.
Tests were conducted using the following liniment formula on human skin cancer grown in nude mice. In these tests, human cancer cells (fast growing) called Lox, were used. It took two weeks for the tumors to develop in the mice.














Ingredient
By weight









pancreatin
100 mg 



pepsin
50 mg



betaine HCL
150 mg 



emulsified vitamin A
 5 mg



zinc citrate
50 mg



pancrelipase
100 mg 



fenugreek
100 mg 



papain
25 mg



amylase
40 mg



ox bile extract
75 mg



apple cider vinegar
trace amount



garlic clove
trace amount










The liniment was prepared by grinding the ingredients in a mortar and pestle at ambient temperature. The texture was that of a skin ointment, which was applied once daily to the tumors.
The tests were conducted on large, medium and small tumors. The graph of FIG. 1 shows results of treatment on large tumors. The tumor volume of a control group was compared to the tumor volume of a treated group. The results show that after 16 days of treatment the control group tumor volume increased from the third day to the sixteenth day by nearly 7000%, the treated group increased by only 2000%.
This proved that the liniment of this invention retarded the growth of the large tumors.
Separate test were conducted on small and medium sized tumors. The same formulation of the liniment was used. The table below compares the volume in cubic millimeters of the control group as compared to the treated group. In the small tumor treated group, several of the tumors completely disappeared.










Effect of Treatment on the Volume of Small and Medium Human Skin


Cancer Tumors Grown in Nude Mice












Control (small)
Treated (small)
Control (medium)
Treated (medium)
















Mouse

Mouse

Mouse

Mouse




Number
Tumor Volume
Number
Tumor Volume
Number
Tumor Volume
Number
Tumor Volume



















Dec. 17, 2006
1
23.95
1
22.4
1
68.62
1
61.74



2
21.42
2
16.35
2
51.39
2
56.38



3
16.17
3
16.13
3
47.95
3
51.44



4
10.76
4
15.25
4
41.63
4
31.72





5
14.75
5
28.33
5
29.79





6
10.32












Mean
18.075

15.86666667
47.584
46.214















Dec. 20, 2006
1
40.83
1
23.41
1
167.64
1
146.12



2
27.46
2
0
2
99.71
2
124.16



3
26.52
3
0
3
93.84
3
88.27



4
22.44
4
0
4
80.5
4
85.44





5
0
5
70.34
5
59.63





6
0












Mean
29.3125
3.901666667

102.406
100.724










% change
13.3

98.36


of control















Dec. 23, 2006
1
87.85
1
57.89
1
285.93
5
282.44



2
42.71
2
45.88
2
168.63
4
199.5



3
29.8
3
28.19
3
168.27
2
161.42



4
27.15
4
0
4
156.98
1
123.8





5
0
5
141.79
3
66.33





6
0











Mean
46.8775
21.99333333
184.32
166.698


% change

46.9

90.44


of control

## Claims

1. A method of reducing or limiting the growth of human melanoma skin cancer tumors comprising providing a liniment consisting of pancreatin, pepsin, betaine HCL, emulsified vitamin A, zinc, pancrelipase, fenugreek, papain, amylase ox bile extract, trace amounts of cider vinegar and trace amounts of minced garlic clove and applying the liniment to the tumors.

2. The method of reducing or limiting the growth of treating human skin cancer tumors of claim 1, wherein the application of the liniment is repeated a plurality of times.

3. The method of reducing or limiting the growth of treating human skin cancer tumors of claim 1, wherein the application of the liniment is repeated on a daily basis.

4. The method of reducing or limiting the growth of human skin cancer tumors of claim 1 in which the pancreatin, pepsin, betaine HCL, emulsified vitamin A, and zinc, pancrelipase, fenugreek, papain, amylase and ox bile extract ingredients are present in approximately equal amounts.

5. A method of reducing or limiting the growth of human melanoma skin cancer tumors comprising preparing a liniment consisting of pancreatin, pepsin, betaine HCL, emulsified vitamin A, zinc, pancrelipase, fenugreek, papain, amylase and ox bile extract and applying the liniment to the tumors.

6. The method of reducing or limiting the growth of human skin cancer tumors of claim 5 in which the ingredients are present in approximately equal amounts.

7. The method of reducing or limiting the growth of human skin cancer tumors of claim 5 in which the ingredients are ground together at ambient temperature until they reach a thick ointment consistency.

8. The method of reducing or limiting the growth of human skin cancer tumors of claim 5, wherein the application of the liniment is repeated a plurality of times.

9. The method of reducing or limiting the growth of treating human skin cancer tumors of claim 5, wherein the application of the liniment is repeated on a daily basis.

10. The method of reducing or limiting the growth of human skin cancer tumors of claim 1 or 5, wherein the vitamin A is emulsified in a solution selected from water and a mixture of water and acacia with d-alpha tocopherol as an antioxidant.

11. The method of reducing or limiting the growth of human skin cancer tumors of claim 1 or 5, wherein the zinc is in the form of zinc citrate.