Exhibit 21
 MERCK & CO., INC. SUBSIDIARIES
as of 12/31/08
  Country or StateName
    
    of IncorporationAbmaxis Inc.
    
    DelawareAncare Australia (Pty) Limited1
    
    AustraliaAncare Ireland Limited1
    
    IrelandAnimal Health Care South Africa (Pty) Limited1
    
    South AfricaASP, Inc.1
    
    GeorgiaBanyu Pharmaceutical Co., Ltd.
    
    JapanBeijing Merial Vital Laboratory Animal Technology Co. Ltd.1
    
    ChinaBRC Ltd.
    
    BermudaCharles E. Frosst (U.K.) Limited
    
    United KingdomChibret Pharmazeutische GmbH
    
    GermanyCloverleaf International Holdings S.a.r.l.
    
    LuxembourgComsort, Inc.
    
    DelawareCoophavet S.A.S.1
    
    FranceCrosswinds B.V.
    
    NetherlandsDieckmann Arzneimittel GmbH
    
    GermanyEuropean Insurance Risk Excess Limited
    
    IrelandFarmacox-Companhia Farmaceutica, Lda
    
    PortugalFarmasix-Produtos Farmaceuticos, Lda
    
    PortugalFinanciere MSD S.A.S.
    
    FranceFontelabor-Produtos Farmaceuticos, Lda.
    
    PortugalFregenal Holdings S.A.
    
    PanamaFrosst Iberica, S.A.
    
    SpainFrosst Laboratories, Inc.
    
    DelawareFrosst Portuguesa  Produtos Farmaceuticos, Lda.
    
    PortugalGlycoFi, Inc.
    
    DelawareHangzhou MSD Pharmaceutical Company Limited1
    
    ChinaHawk and Falcon L.L.C.
    
    DelawareHeptafarma Companhia Farmaceutica, Lda.
    
    PortugalIM Merial Holdings, LLC1
    
    DelawareInternational Indemnity Ltd.
    
    BermudaIstituto Di Richerche Di Biologia Molecolare S.p.A.
    
    ItalyIstituto Gentili S.p.A./Inc.
    
    Italy/DelawareJohnson & Johnson  Merck Consumer Pharmaceuticals Company1
    
    New JerseyJohnson & Johnson Consumer Pharma of Canada1
    
    CanadaKBI Inc.
    
    DelawareKBI Sub Inc.
    
    DelawareKBI-E Inc.
    
    DelawareKBI-P Inc.
    
    DelawareKiinteisto Oy Viistotie 11
    
    FinlandLaboratoires Merck Sharp & Dohme-Chibret SNC
    
    France




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##### 



Country or StateName
    
    of IncorporationLaboratorios Abello, S.A.
    
    SpainLaboratorios Biopat, S.A.
    
    SpainLaboratorios Chibret, S.A.
    
    SpainLaboratorios Frosst, S.A.
    
    SpainLaboratorios Medichip S.L.
    
    SpainLaboratorios Merial Peru S.A.1
    
    PeruLaboratorios Neurogard, S.A.
    
    SpainLaboratorios Quimico-Farmaceuticos Chibret, Lda.
    
    PortugalLOSPAR Partnership1
    
    DelawareMaple Leaf Holdings SRL
    
    BarbadosMCM Vaccine Co.1
    
    PennsylvaniaMerck and Company, Incorporated
    
    DelawareMerck Borinquen Holdings, Inc.
    
    DelawareMerck Capital Ventures, LLC
    
    DelawareMerck Cardiovascular Health Company
    
    NevadaMerck Frosst Canada Ltd.
    
    CanadaMerck Frosst Company
    
    CanadaMerck Frosst Finco LP
    
    CanadaMerck Frosst Schering Pharma GP1
    
    CanadaMerck HDAC Research, LLC
    
    DelawareMerck Holdings II Corp.
    
    DelawareMerck Holdings LLC
    
    DelawareMerck Respiratory Health Company
    
    NevadaMerck SH Inc.
    
    DelawareMerck Sharp & Dohme (Argentina) Inc.
    
    DelawareMerck Sharp & Dohme (Asia) Limited
    
    Hong KongMerck Sharp & Dohme (Australia) Pty. Limited
    
    AustraliaMerck Sharp & Dohme (China) Limited
    
    Hong KongMerck Sharp & Dohme (Enterprises) B.V.
    
    NetherlandsMerck Sharp & Dohme (Europe) Inc.
    
    DelawareMerck Sharp & Dohme (Holdings) B.V.
    
    NetherlandsMerck Sharp & Dohme (Holdings) Limited
    
    United KingdomMerck Sharp & Dohme (I.A.) Corp.
    
    DelawareMerck Sharp & Dohme (International) Limited
    
    BermudaMerck Sharp & Dohme (Investments) B.V.
    
    NetherlandsMerck Sharp & Dohme (Ireland) Ltd.
    
    BermudaMerck Sharp & Dohme (Israel  1996) Company Ltd.
    
    IsraelMerck Sharp & Dohme (Italia) S.p.A.
    
    ItalyMerck Sharp & Dohme (Lebanon) S.A.L.
    
    LebanonMerck Sharp & Dohme (Middle East) Limited
    
    CyprusMerck Sharp & Dohme (New Zealand) Limited
    
    New ZealandMerck Sharp & Dohme (Panama) S.A.
    
    PanamaMerck Sharp & Dohme (Puerto Rico) Ltd.
    
    BermudaMerck Sharp & Dohme (Singapore) Ltd.
    
    BermudaMerck Sharp & Dohme (Sweden) A.B.
    
    SwedenMerck Sharp & Dohme (Switzerland) GmbH
    
    SwitzerlandMerck Sharp & Dohme Asia Pacific Services Pte Ltd.
    
    SingaporeMerck Sharp & Dohme B.V.
    
    NetherlandsMerck Sharp & Dohme Biologics (Ireland) Ltd.
    
    Bermuda
 2




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##### 



Country or StateName
    
    of IncorporationMerck Sharp & Dohme Bulgaria EOOD
    
    BulgariaMerck Sharp & Dohme Chibret A.G.
    
    SwitzerlandMerck Sharp & Dohme Comercializadora, S. de R.L. de C.V.
    
    MexicoMerck Sharp & Dohme d.o.o.
    
    CroatiaMerck Sharp & Dohme de Espana, S.A.
    
    SpainMerck Sharp & Dohme de Mexico S.A. de C.V.
    
    MexicoMerck Sharp & Dohme de Puerto Rico, Inc.
    
    DelawareMerck Sharp & Dohme de Venezuela S.R.L.
    
    VenezuelaMerck Sharp & Dohme Farmaceutica Ltda.
    
    BrazilMerck Sharp & Dohme Finance Europe Limited
    
    United KingdomMerck Sharp & Dohme GmbH
    
    AustriaMerck Sharp & Dohme IDEA AG
    
    SwitzerlandMerck Sharp & Dohme Industria Quimica e Veterinaria Limitada
    
    BrazilMerck Sharp & Dohme inovativna zdravila d.o.o.
    
    SloveniaMerck Sharp & Dohme International Services B.V.
    
    NetherlandsMerck Sharp & Dohme Ireland (Human Health) Ltd
    
    IrelandMerck Sharp & Dohme Ísland hf
    
    IcelandMerck Sharp & Dohme Japan Co., Ltd.
    
    JapanMerck Sharp & Dohme Limited
    
    United KingdomMerck Sharp & Dohme Manufacturing
    
    IrelandMerck Sharp & Dohme Manufacturing Holdings
    
    BermudaMerck Sharp & Dohme OU
    
    EstoniaMerck Sharp & Dohme Peru SRL
    
    PeruMerck Sharp & Dohme Pharmaceuticals LLC
    
    RussiaMerck Sharp & Dohme Pharmaceuticals SRL
    
    BarbadosMerck Sharp & Dohme Quimica de Puerto Rico Ltd.
    
    BermudaMerck Sharp & Dohme Quimica de Puerto Rico, Inc.
    
    DelawareMerck Sharp & Dohme Research Ltd.
    
    BermudaMerck Sharp & Dohme Romania SRL
    
    RomaniaMerck Sharp & Dohme S. de R.L. de C.V.
    
    MexicoMerck Sharp & Dohme S.A.
    
    MoroccoMerck Sharp & Dohme SIA
    
    LatviaMerck Sharp & Dohme Singapore Trading Pte. Ltd.
    
    SingaporeMerck Sharp & Dohme Tunisie Sarl
    
    TunisiaMerck Sharp & Dohme, Limitada
    
    PortugalMerck Sharp and Dohme Holdings de Mexico, S.A. de C.V.
    
    MexicoMerck Sharp Dohme Ilaclari Limited Sirketi
    
    TurkeyMerck Technology (U.S.) Company, Inc.
    
    NevadaMerial (IA) LLP1
    
    Puerto RicoMerial (Thailand) Ltd1
    
    ThailandMerial Animal Health Co. Ltd.1
    
    ChinaMerial Animal Health Limited (U.K.)1
    
    United KingdomMerial Animal Health Limited1
    
    IrelandMerial Argentina SA1
    
    ArgentinaMerial Asia Pte, Ltd.1
    
    SingaporeMerial Australia Pty Ltd1
    
    AustraliaMerial B.V.1
    
    NetherlandsMerial Belgium 1
    
    BelgiumMerial Canada, Inc.1
    
    Canada
 3




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##### 



Country or StateName
    
    of IncorporationMerial Colombia S.A.1
    
    ColombiaMerial de Mexico S.A. de C.V.1
    
    MexicoMerial Distribution SAS1
    
    FranceMerial Finance LLC1
    
    DelawareMerial GmbH1
    
    GermanyMerial Hong Kong Limited1
    
    Hong KongMerial Inc.1
    
    DelawareMerial International Trading (Shanghai) Co., Ltd.1
    
    ChinaMerial Italia SpA1
    
    ItalyMerial Japan, Limited1
    
    JapanMerial Korea Ltd1
    
    KoreaMerial Laboratorios SA1
    
    SpainMerial Limited/LLC1
    
    United Kingdom/DelawareMerial Mexico S.A. de C.V.1
    
    MexicoMerial Nanjing Animal Health Co. Ltd.1
    
    ChinaMerial New Zealand Limited1
    
    New ZealandMerial Norden A/S1
    
    DenmarkMerial Philippines, Inc.1
    
    PhilippinesMerial Portuguesa  Saude Animal LDA1
    
    PortugalMerial Production SAS1
    
    FranceMerial SA1
    
    UruguayMerial SAS 1
    
    FranceMerial Saude Animal Ltda1
    
    BrazilMerial Select, Inc.1
    
    GeorgiaMerial South Africa (Proprietary) Limited1
    
    South AfricaMerial Taiwan Co., Ltd.1
    
    TaiwanMerial Technologies, Inc.1
    
    DelawareMerial Venezuela , C.A. 1
    
    VenezuelaML Holdings (Canada) Inc.
    
    CanadaMSD (Nippon Holdings) BV
    
    NetherlandsMSD (Norge) A/S
    
    NorwayMSD (Proprietary) Limited
    
    South AfricaMSD (Shanghai) Pharmaceuticals Consultancy Co., Ltd.
    
    ChinaMSD (Thailand) Ltd.
    
    ThailandMSD Australia Superannuation Pty Ltd.
    
    AustraliaMSD Brazil (Investments) B.V.
    
    NetherlandsMSD Chibropharm GmbH
    
    GermanyMSD China (Investments) B.V.
    
    NetherlandsMSD Eurofinance L.P.
    
    BermudaMSD Finance B.V.
    
    NetherlandsMSD Finland Oy
    
    FinlandMSD International Holdings, Inc.
    
    DelawareMSD Investment Holdings (Ireland)
    
    IrelandMSD Ireland (Holdings) S.a.r.l.
    
    LuxembourgMSD Ireland Resources
    
    IrelandMSD Korea Ltd.
    
    KoreaMSD Latin America Services S. de R.L. de C.V.
    
    MexicoMSD Limited
    
    United KingdomMSD Magyarország Kereskedelmi es Szolgaltato Kft
    
    Hungary
 4




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##### 



Country or StateName
    
    of IncorporationMSD Mexico Investments B.V.
    
    NetherlandsMSD Overseas Manufacturing Co (Ireland)
    
    IrelandMSD Overseas Manufacturing Co.
    
    BermudaMSD Pharmaceuticals Private Limited
    
    IndiaMSD Polska Sp.z.o.o.
    
    PolandMSD Puerto Rico Holdings, Inc.
    
    Puerto RicoMSD Regional Business Support Center GmbH
    
    GermanyMSD Scandinavia AS
    
    NorwayMSD Sharp & Dohme GmbH
    
    GermanyMSD Stamford Singapore Pte Ltd
    
    SingaporeMSD Technology Singapore Pte. Ltd.
    
    SingaporeMSD Tuas Singapore Pte. Ltd.
    
    SingaporeMSD Unterstutzungskasse GmbH
    
    GermanyMSD Ventures Singapore Pte. Ltd.
    
    SingaporeMSD Vostok B.V.
    
    NetherlandsMSD-Essex GmbH1
    
    SwitzerlandMSDJ Holdings (Canada) Inc.
    
    CanadaMSD-SP Ltd.1
    
    United KingdomMSP Distribution Services (C) LLC1
    
    NevadaMSP Distribution Services (R) LLC1
    
    NevadaMSP Singapore Company, LLC1
    
    DelawareMSP Technology (U.S.) Company, LLC1
    
    DelawareNeopharmed S.p.A.
    
    ItalyNomad New Jersey, Inc.1
    
    New JerseyNovaCardia, Inc.
    
    DelawareP.T. Merck Sharp & Dohme Indonesia
    
    IndonesiaPasteur Vaccins S.A.1
    
    FranceRhone-Merieux Limited1
    
    United KingdomRosetta Biosoftware UK Limited
    
    United KingdomRosetta Inpharmatics LLC
    
    DelawareSanofi Pasteur MSD A/S1
    
    DenmarkSanofi Pasteur MSD AB1
    
    SwedenSanofi Pasteur MSD AG1
    
    SwitzerlandSanofi Pasteur MSD ApS1
    
    DenmarkSanofi Pasteur MSD AS1
    
    NorwaySanofi Pasteur MSD Gestion S.A.1
    
    FranceSanofi Pasteur MSD GmbH1
    
    AustriaSanofi Pasteur MSD GmbH1
    
    GermanySanofi Pasteur MSD Ltd.1
    
    United KingdomSanofi Pasteur MSD Ltd.1
    
    IrelandSanofi Pasteur MSD N.V./S.A.1
    
    BelgiumSanofi Pasteur MSD Oy1
    
    FinlandSanofi Pasteur MSD S.A.1
    
    PortugalSanofi Pasteur MSD S.A.1
    
    SpainSanofi Pasteur MSD S.p.A.1
    
    ItalySanofi Pasteur MSD SNC1
    
    FranceSFPA, Inc.1
    
    DelawareSharp & Dohme, S.A.
    
    SpainSirna Therapeutics, Inc.
    
    Delaware
 5




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##### 



Country or StateName
    
    of IncorporationTELERx Marketing Inc.
    
    PennsylvaniaThe MSD Foundation Limited
    
    United KingdomThomas Morson & Son Limited
    
    United KingdomTransrow Manufacturing Ltd.1
    
    BermudaUAB Merck Sharp & Dohme
    
    LithuaniaVariopharm Arzneimittel GmbH
    
    GermanyVin-Mex, S.A.1
    
    Mexico
 
 1
    
    own less than 100% 6