RapidVap Vacuum, N2 & N2/48 

Evaporation Systems

Models

7900000 7900001

7900002 7900003

7900010 7900011

7900012 7900013

7910000 7910001

7910010 7910011

7910012 7910013

7910014 7910015
Copyright © 2017 Labconco Corporation. The information contained in this manual and the accompanying 

products are copyrighted and all rights reserved by Labconco Corporation. Labconco Corporation reserves 

the right to make periodic design changes without obligation to notify any person or entity of such change.

Returned or Damaged Goods

Do not return goods without the prior authorization from Labconco. Unauthorized returns will not be 

accepted. If your shipment was damaged in transit, you must file a claim directly with the freight carrier. 

Labconco Corporation and its dealers are not responsible for shipping damages.

The United States Interstate Commerce Commission rules require that claims be filed with the delivery 

carrier within fifteen (15) days of delivery.

Limitation of Liability

The disposal and/or emission of substances used in connection with this equipment may be governed by 

various federal, state, or local regulations. All users of this equipment are required to become familiar with 

any regulations that apply in the user’s area concerning the dumping of waste materials in or upon water, 

land, or air and to comply with such regulations. Labconco Corporation is held harmless with respect to 

user’s compliance with such regulations.

Contacting Labconco Corporation

If you have questions that are not addressed in this manual, or if you need technical assistance, contact 

Labconco’s Customer Service Department or Labconco’s Product Service Department at 1-800-821-5525 

or 1-816-333-8811, between the hours of 7:30 a.m. and 5:30 p.m., Central Standard Time.

Part #7490100, Rev. L

ECO #N327

Warranty

Labconco Corporation provides a warranty to the original buyer for the repair or replacement of parts and 

reasonable labor as a result of normal and proper use of the equipment with compatible chemicals. Broken 

glassware and maintenance items, such as filters, gaskets, light bulbs, finishes and lubrication are not 

warranted. Excluded from warranty are products with improper installation, erratic electrical or utility supply, 

unauthorized repair and products used with incompatible chemicals.

The warranty for RapidVap® Vacuum, N2 & N2/48 Evaporation Systems will expire one year from date of 

installation or two years from date of shipment from Labconco, whichever is sooner. Warranty is nontransferable and only applies to the owner (organization) of record.

Buyer is exclusively responsible for the set-up, installation, verification, decontamination or calibration of 

equipment. This limited warranty covers parts and labor, but not transportation and insurance charges. If the 

failure is determined to be covered under this warranty, the dealer or Labconco Corporation will authorize 

repair or replacement of all defective parts to restore the unit to operation. Repairs may be completed by 3rd

party service agents approved by Labconco Corporation. Labconco Corporation reserves the rights to limit this 

warranty based on a service agent’s travel, working hours, the site’s entry restrictions and unobstructed access 

to serviceable components of the product. 

Under no circumstances shall Labconco Corporation be liable for indirect, consequential, or special damages 

of any kind. This warranty is exclusive and in lieu of all other warranties whether oral, or implied.
ORIGINAL INSTRUCTIONS

TABLE OF CONTENTS

CHAPTER 1: INTRODUCTION 1

About This Manual 2

Typographical Conventions 3

Your Next Step 3

CHAPTER 2: PREREQUISITES 5

Electrical Requirements 5

Location and Exhaust Requirements 6

Vacuum Pump Requirements 6

Vacuum Line Traps 7

Nitrogen Supply Requirements 8

Space Requirements 8

Tools Required 8

Your Next Step 8

CHAPTER 3: GETTING STARTED 9

Unpacking Your RapidVap 9

RapidVap Components 10

Setting Up Your RapidVap 12

Vacuum Pump Connection 12

Sample Block 13

Nitrogen Gas Connection 15

Exhaust Port 15

Electrical Connection 15

Calibrate the Vacuum Sensor 15

Chemical Attack on RapidVap Components 15

Solvent Safety Precautions 17

Your Next Step 18
CHAPTER 4: USING YOUR RAPIDVAP 19

Planning 19

Glassware Selection and Speed Setting Guidelines 20

Loading Glassware Into the RapidVap 22

Heat Setting Guidelines 23

Time Setting Guidelines 27

RapidVap Controls 29

Operating the RapidVap Controls 30

Operating The RapidVap 32

Operational Notes 33

Interrupting a Cycle After it Has Begun 33

End Alarms 33

RS-232 Communications 34

RS-232 Programming Syntax 34

RS-232 Hardware Required 36

CHAPTER 5: MAINTAINING YOUR RAPIDVAP 37

CHAPTER 6: MODIFYING YOUR RAPIDVAP 39

Changing the Sample Blocks 39

Installing the Optional Lid Heater 40

CHAPTER 7: TROUBLESHOOTING 41

APPENDIX A: RAPIDVAP AND RAPIDVAP N2 COMPONENTS 45

APPENDIX B: RAPIDVAP DIMENSIONS 52

APPENDIX C: RAPIDVAP SPECIFICATIONS 54

Wiring Diagram (115V) 56

Wiring Diagram (230V) 57

Evaporation Rates 58

RapidVap Vacuum Models 58

RapidVap N2 Models 59

RapidVap N2/48 Models 63

APPENDIX D: RAPIDVAP ACCESSORIES 65

RapidVap Vacuum Model Accessories 65

RapidVap N2 Model Accessories 68

RapidVap N2/48 Model Accessories 70
Product Service 1-800-522-7658 1

Original instructions

CHAPTER 1

INTRODUCTION

Congratulations on your purchase of a Labconco RapidVap. Labconco 

manufactures two types of RapidVaps - one utilizes vacuum and the other utilizes 

nitrogen as an aid to evaporation. Each model is available for operation on 115V 

or 230V.

Superior evaporation rates are achieved by the unique blending of several gentle 

forces on the sample. Samples are subjected to a gyrating motion causing the 

liquid to form a vortex configuration which greatly increases the surface area and 

hence the ability to evaporate. A precisely controlled amount of thermal energy 

can be supplied to the sample to heat it. In the vacuum model, the sample can be 

subjected to a decreased pressure by the application of a regulated vacuum. In 

summary, the vacuum model RapidVap performance is maximized by increasing 

the sample’s surface area, increasing temperature and decreasing pressure.

In the RapidVap N2, a stream of nitrogen or dry gas is directed downward onto the 

surface of the sample. This reduces the partial pressure directly over the liquid to 

speed evaporation and helps remove the solvent as it evaporates. In summary, the 

RapidVap N2 performance is maximized by increasing the sample’s surface area, 

increasing temperature and directing gas over the sample.

The gyrating motion imparted to the sample causes other, more subtle effects to 

occur. Excellent mixing of the components in the liquid sample is obtained. Also, 

as the liquid forms the vortex shape, a centrifugal force is established which forces 

the liquid outward against the tube walls. This helps prevent bumping and in turn 

allows the evaporation rate to be optimized.

The microprocessor which controls the operation of the heater and the motor 

provides excellent regulation and reproducibility of protocols. The end of the run 

can be signaled by the automatic end point system or by a manually preset timer. 

Nine different protocols can be stored in memory so exact test parameters can be 

easily repeated.
Chapter 1: Introduction

2 Product Service 1-800-522-7658

Original instructions

About This Manual

This manual is designed to help you learn how to install, use, and maintain your 

RapidVap. Instructions for performing routine maintenance and making minor 

modifications to your RapidVap are also included.

Chapter 1: Introduction provides a brief overview of the RapidVap, explains the 

organization of the manual, and defines the typographical conventions used in the 

manual.

Chapter 2: Prerequisites explains what you need to do to prepare your site before 

you install your RapidVap. Electrical and exhaust requirements are discussed as 

well as vacuum pump or nitrogen requirements.

Chapter 3: Getting Started contains the information you need to properly unpack, 

inspect, install, and test your RapidVap.

Chapter 4: Using Your RapidVap discusses the basic operation of your RapidVap. 

Information on how to arrange the samples inside your RapidVap and select an 

operating cycle is included.

Chapter 5: Maintaining Your RapidVap explains how to perform routine 

maintenance on your RapidVap.

Chapter 6: Modifying Your RapidVap describes how to install other blocks and the 

optional lid heater.

Chapter 7: Troubleshooting contains a table of problems you may encounter while 

using your RapidVap, including the probable causes of the problems, and 

suggested corrective actions.

Appendix A: RapidVap and RapidVap N2 Components contains labeled diagrams 

of the components of the RapidVaps.

Appendix B: RapidVap Dimensions contains comprehensive diagrams showing the 

dimensions for the RapidVap and RapidVap N2.

Appendix C: RapidVap Specifications contains product specifications. Wiring 

diagrams for both the 115V and 230V RapidVaps are also included.

Appendix D: RapidVap Accessories lists the part numbers and descriptions of all of 

the accessories available for your RapidVap.
Chapter 1: Introduction

Product Service 1-800-522-7658 3

Original instructions

Typographical Conventions

Recognizing the following typographical conventions will help you understand and 

use this manual:

 Book, chapter, and section titles are shown in italic type (e.g., Chapter 3: 

Getting Started).

 Steps required to perform a task are presented in a numbered format.

 Comments located in the margins provide suggestions, reminders, and 

references.

 Critical information is presented in boldface type in paragraphs that are 

preceded by the exclamation icon. Failure to comply with the information 

following an exclamation icon may result in injury to the user or permanent 

damage to your RapidVap.

 Les informations critiques sont présentées en caractères gras dans les 

paragraphes qui sont précédés par le point d'exclamation. Le non respect de 

l'information suite à un point d'exclamation peut entraîner des blessures pour 

l'utilisateur ou des dommages permanents à votre RapidVap.

 Important information is presented in capitalized type in paragraphs that are 

preceded by the pointer icon. It is imperative that the information contained in 

these paragraphs be thoroughly read and understood by the user.

 Information that is specific to a particular model of RapidVap is preceded by a 

letter icon. The V icon indicates the text is specific to the Vacuum model. The 

N icon indicates the text is specific to the RapidVap N2 model.

 CAUTION – See Manual. When this symbol is on the unit it indicates a 

caution that is detailed in this manual.

 ATTENTION – Voir le manuel. Lorsque ce symbole est allumé l'unité, il 

indique une mise en garde qui est détaillée dans ce manuel.

Your Next Step

If your RapidVap needs to be installed, proceed to Chapter 2: Prerequisites to 

ensure your installation site meets all of the requirements. Then, go to Chapter 3: 

Getting Started for instructions on how to install your RapidVap and make all of 

the necessary connections.

For information on the operational characteristics of your RapidVap, go to Chapter 

4: Using Your RapidVap.

If your RapidVap is installed and you need to perform routine maintenance on the 

RapidVap, proceed to Chapter 5: Maintaining Your RapidVap.

!



V N

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Chapter 1: Introduction

4 Product Service 1-800-522-7658

Original instructions

For information on making modifications to the configuration of your RapidVap 

go to Chapter 6: Modifying Your RapidVap.

Refer to Chapter 7: Troubleshooting if you are experiencing problems with your 

RapidVap.
Product Service 1-800-522-7658 5

Original instructions

CHAPTER 2

PREREQUISITES

Before you install your RapidVap, you need to prepare your site for installation. 

Carefully examine the location where you intend to install your RapidVap. You 

must be certain that the area is level and of solid construction. In addition, an 

exhaust means must be provided and a source of nitrogen must be available for the 

RapidVap N2. An electrical source must be located near the installation site.

Carefully read this chapter to learn:

 the electrical supply requirements.

 the exhaust requirements.

 the nitrogen supply requirements for the RapidVap N2.

 the vacuum pump requirements for the RapidVap Vacuum.

Refer to Appendix C: RapidVap Specifications for complete RapidVap electrical 

and environmental conditions, specifications and requirements.

If the unit is not operated as specified in this manual it may 

impair the protection provided by the unit.

Si l'appareil n'est pas utilisé comme spécifié dans ce manuel, il 

peut compromettre la protection offerte par l'appareil.

Electrical Requirements

If your RapidVap is a Vacuum model, a dedicated electrical outlet is required. 

This outlet requires a 20 Amp circuit breaker or fuse for models rated at 115V (60 

Hz). A 10 Amp circuit breaker or fuse is required for models rated at 230V (50/60 

Hz). 115V models are equipped with a 20 Amp NEMA 5-20P plug. 230V models 

are equipped with a 16 Amp CEE 7/7 plug. It may be necessary to remove the 

plug and install a different plug to match the available receptacle.

V

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Chapter 2: Prerequisites

6 Product Service 1-800-522-7658

Original instructions

If your RapidVap is a Nitrogen model, a dedicated electrical outlet is required. 

This outlet requires a 15 Amp circuit breaker or fuse for models rated at 115V (60 

Hz) or an 8 Amp circuit breaker or fuse is required for 230V (50/60 Hz) models. 

115V models are equipped with a 20 Amp NEMA 5-20P plug. 230V models are 

equipped with a 16 Amp CEE 7/7 plug. It may be necessary to remove the plug 

and install a different plug to match the available receptacle.

Do not use any detachable power cord that is not adequately rated for the unit.

N'utilisez pas de cordon d'alimentation amovible qui n'est pas suffisamment 

puissant pour l'unité.

Location and Exhaust Requirements

The RapidVap Vacuum Evaporation System should be located within a fume hood 

if hazardous or flammable solvents are used. In all cases, regardless of the solvent 

used, it is strongly recommended that the vacuum pump is located and vented in a 

fume hood.

The RapidVap N2 Evaporation System should be located within a fume hood if 

hazardous or flammable solvents are used. In all cases, regardless of the solvent 

used, it is recommended that the exhaust hose is vented into a fume hood or other 

laboratory ventilation device.

Do not position the unit so that it is difficult to operate the main 

disconnect device.

Ne pas placer l'appareil de sorte qu'il est difficile de faire 

fonctionner le dispositif de déconnexion principal.

Vacuum Pump Requirements

A vacuum pump must be provided by the user. For most applications, it is 

recommended that the vacuum pump is capable of a free air flow of 63 L/min and 

1.5 mbar vacuum although, in some applications other pumps may be satisfactory 

or be required. The inlet fitting on the vacuum pump must be suitable for 0.50 I.D. 

hose.

Biological samples, for example, are often dissolved in water, a high boiling point 

solvent, and are often heat liable. Such samples require the high vacuum 

achievable with a mechanical vacuum pump, usually with an ultimate vacuum of

7 x 10-3 mBar to achieve a good evaporation rate.

N

V

N

V

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Chapter 2: Prerequisites

Product Service 1-800-522-7658 7

Original instructions

On the other hand, samples dissolved in methylene chloride, a low boiling point 

solvent, can be efficiently concentrated using a water aspirator.

The nomograms in Chapter 4: Using Your RapidVap will help determine the 

boiling point of a solvent at pressures below atmospheric. This can serve as a 

guide to the appropriate vacuum source.

TO INSURE THAT AGGRESSIVE SAMPLES USED IN THE 

RAPIDVAP DO NOT DAMAGE THE VACUUM PUMP, IT IS 

RECOMMENDED THAT ALL INTERNAL WETTED PARTS 

ARE PTFE OR PTFE COATED. TO PREVENT A HAZARDOUS 

CONDITION, THE PUMP MUST BE SUITABLE FOR

HANDLING THE VAPORS FROM THE SOLVENTS THAT 

WILL BE EVAPORATED IN THE RAPIDVAP.

CAUTION: When selecting the vacuum pump it is very 

important to consider the flammability of the solvents that will 

be used. If the solvents are flammable, an explosion proof 

vacuum pump is recommended.

ATTENTION: Lors de la sélection de la pompe à vide, il est très 

important d'examiner l'inflammabilité des solvants qui seront 

utilisés. Si les solvants sont inflammables, d'une pompe à vide à

l'épreuve des explosions est recommandé

Vacuum Line Traps

When using a mechanical pump which is not corrosion resistant, a trap must be 

used in the vacuum line to prevent damage from solvent vapors. This is most often 

a condenser-type trap chilled with dry ice/acetone. When evaporating acids, it is 

advisable to include a soda lime acid trap in the vacuum line. This adds additional 

protection for the pump.

Several components within the RapidVap are made from 

stainless steel and can be degraded if exposed to acids. Before 

evaporating acids, be sure to contact Labconco.

Plusieurs composants du RapidVap sont en acier inoxydable et

peuvent être dégradés s'ils sont exposés à des acides. Avant de 

s'évaporer acides, n'oubliez pas de contacter Labconco.

A moisture trap and radioisotope trap are also available. When evaporating high 

boiling point solvents, a liquid trap should be positioned between the RapidVap 

and the vacuum pump to prevent liquid from entering the pump. Refer to 

Appendix D: RapidVap Accessories for ordering information.

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Chapter 2: Prerequisites

8 Product Service 1-800-522-7658

Original instructions

Nitrogen Supply Requirements

The 1/4" I.D. hose on the rear of the RapidVap N2 must be attached to a source of 

nitrogen or other suitable gas. Pressure must NOT exceed 30 psi. A regulator 

must be supplied by the user. The nitrogen supply must be capable of 0.6 CFM 

flow rate for the 8 place RapidVap N2. The RapidVap N2/48 requires a flow rate 

of 3.5 CFM. A suitable barb or compression fitting must be supplied by the user.

Space Requirements

Refer to Appendix C: RapidVap Specifications for dimensional drawings of the 

RapidVap.

Tools Required

Common hand tools are required to set up the RapidVap. A screwdriver or 5/16" 

socket is needed to attach hose clamps. A tubing cutter or knife is needed to 

shorten exhaust hoses. If the sample block must be installed or exchanged, 

attaching nuts on the RapidVap Vacuum and RapidVap N2 require a 7/16" socket. 

The manifold guides, which secure the block on the RapidVap N2/48, require a 

9/16" socket.

Your Next Step

After you have determined that the location for your RapidVap accommodates the 

installation and operational requirements, you are ready to unpack and install your 

RapidVap. Proceed to Chapter 3: Getting Started.

N
Product Service 1-800-522-7658 9

Original instructions

CHAPTER 3

GETTING STARTED

Now that the site for your RapidVap is properly prepared, you are ready to unpack, 

inspect, install, and test your RapidVap. Read this chapter to learn how to:

 unpack and move your RapidVap.

 set up your RapidVap.

 connect the vacuum pump or nitrogen source to your RapidVap.

 connect the electrical supply source to your RapidVap.

 properly exhaust your RapidVap.

 calibrate the vacuum sensor.

 solvent safety precautions.

Depending upon which model of RapidVap you are installing, you will need 

common hand tools including a flat blade screw driver, a 7/16" socket and an 

adjustable wrench to complete the instructions in this chapter.

The RapidVap weighs over 70 lbs. (33 Kg). The carton allows 

for lifting with a mechanical lift truck or hand truck. If you 

must lift the RapidVap manually, use at least two (2) persons 

and follow safe-lifting guidelines.

Unpacking Your RapidVap

Carefully unpack your RapidVap and inspect it for damage that may have occurred 

in transit. If your RapidVap is damaged, notify the delivery carrier immediately 

and retain the entire shipment intact for inspection by the carrier.

DO NOT RETURN GOODS WITHOUT THE PRIOR 

AUTHORIZATION OF LABCONCO. UNAUTHORIZED 

RETURNS WILL NOT BE ACCEPTED.

!

The United 

States Interstate 

Commerce 

Commission 

rules require 

that claims be 

filed with the 

delivery carrier 

within fifteen 

(15) days of  delivery.
Chapter 3: Getting Started

10 Product Service 1-800-522-7658

Original instructions

IF YOUR RAPIDVAP WAS DAMAGED IN TRANSIT, YOU 

MUST FILE A CLAIM DIRECTLY WITH THE FREIGHT 

CARRIER. LABCONCO CORPORATION AND ITS DEALERS 

ARE NOT RESPONSIBLE FOR SHIPPING DAMAGES.

Do not discard the carton or packing material for your RapidVap until you have 

checked all of the components and installed and tested the RapidVap.

RapidVap Components

As previously mentioned, Labconco manufactures two types of RapidVap, the 

Vacuum and the Nitrogen models. Each model is available in 115V or 230V.

The different RapidVap models require different assembly components. Locate 

the model of RapidVap you received in the following tables. Verify that the 

components listed are present and undamaged.

Catalog # RapidVap Description

79000-00 RapidVap Vacuum System – 115V 

79000-01 RapidVap Vacuum System – 230V

79000-02 RapidVap Vacuum System – 115V with lid heater

79000-03 RapidVap Vacuum System – 230V with lid heater

79000-10 RapidVap Vacuum System – 115V with RS 232 Interface

79000-11 RapidVap Vacuum System – 230V with RS 232 Interface

79000-12 RapidVap Vacuum System – 115V with lid heater with RS 232 Interface

79000-13 RapidVap Vacuum System – 230V with lid heater with RS 232 Interface

Plus the Following:

Part # Component Description

78286-04 Hose - Vacuum

14888-00 Two (2) Clamps

13364-00

13365-00

Power Cord – 115V

or

Power Cord – 230V

19116-00 Washer (3)

19092-21 Acorn Nut (3)

12556-00 Heat Transfer Grease

74901-00 User’s Manual

74848-00 Cable Assembly RS232 (Models 79000-10, -11, -12, -13)

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Chapter 3: Getting Started

Product Service 1-800-522-7658 11

Original instructions

Since users’ preference of sample size varies, the sample holding block is not 

included with the RapidVap Vacuum System or the RapidVap N2/48 Evaporation 

System. The correct size block must be selected and ordered separately. Refer to 

Appendix D: RapidVap Accessories for block selection.

Catalog # RapidVap Description

79100-00 RapidVap N2 Evaporation System – 115V 

79100-01 RapidVap N2 Evaporation System – 230V

79100-10 RapidVap N2 Evaporation System – 115V with RS 232 Interface

79100-11 RapidVap N2 Evaporation System – 230V with RS 232 Interface

Plus the Following:

Part # Component Description

79131-01 Exhaust Hose

19660-00 One (1) Clamp

79255-00 Eight (8) Sample Tube Caps

13364-00

13365-00

Power Cord – 115V

or

Power Cord – 230V

12556-00 Heat Transfer Grease

74901-00 User’s Manual

74848-00 Cable Assembly RS232 (Models 79100-10, -11)

Catalog # RapidVap Description

79100-12 RapidVap N2/48 Evaporation System – 115V 

79100-13 RapidVap N2/48 Evaporation System – 230V

79100-14 RapidVap N2/48 Evaporation System – 115V with RS 232 Interface

79100-15 RapidVap N2/48 Evaporation System – 230V with RS 232 Interface

Plus the Following:

Part # Component Description

79131-00 Exhaust Hose – 6 ft.

19660-00 One (1) Clamp

13364-00

13365-00

Power Cord – 115V

or

Power Cord – 230V

12556-00 Heat Transfer Grease

74901-00 User’s Manual

74488-00 Manifold Guide (3)

19116-00 Washer (3)

74848-00 Cable Assembly RS232 (Models 74100-14, -15)

If you do not receive one or more of the components listed for your RapidVap, or 

if any of the components are damaged, contact Labconco Corporation immediately 

for further instructions.
Chapter 3: Getting Started

12 Product Service 1-800-522-7658

Original instructions

Setting Up Your RapidVap

After you verify the RapidVap components, move your RapidVap to the location 

where you want to install it. Then, follow the steps listed below.

Vacuum Pump Connection

Connect the pump inlet to the fitting at the right hand rear corner of the RapidVap 

using the hose and clamps provided. Route the hose to prevent kinks. Clamp all 

connections securely. Plug the pump into the pump receptacle on the back of the 

unit and turn the pump switch on if it is so equipped. When evaporating high boiling 

point solvents, a liquid trap should be positioned between the RapidVap and the 

vacuum pump to prevent liquid from entering the pump. It is recommended that the 

vacuum pump is located inside a fume hood. If that is not possible, the exhaust of 

the pump should be directed to a laboratory fume hood or other laboratory 

ventilation device.

V

Optional vacuum 

pump exhaust hose 

to ventilation device

Hose

Vacuum hose

Clamp all connections

Optional liquid trap or 

chilled trap or 

secondary trap

Vacuum pump

inlet fitting

Vacuum pump

power connection
Chapter 3: Getting Started

Product Service 1-800-522-7658 13

Original instructions

There is a switch on the back of the RapidVap Vacuum that is used to select the 

operation of an optional RapidVap Trapping Valve. When the RapidVap is used 

without the Trapping Valve as shown above, set the switch to the “Off” position.

Sample Block

If the RapidVap was not shipped with the sample block installed then it must be 

installed by the user. The sample block must be securely attached to its mounting 

plate. Note the asymmetric hole pattern of the three thru mounting holes. Locate 

the three flat washers either nuts or manifold guides that were shipped with the 

RapidVap. The RapidVap Vacuum uses nuts while the RapidVap N2/48 uses 

guide rods.

Apply a small amount of heat transfer grease that was shipped with the RapidVap 

to the end of the temperature sensor probe that extends up from the bottom of the 

chamber. Position the block over the three studs in the chamber. Install the flat 

washers and either nuts or guide rods. Tighten securely.
Chapter 3: Getting Started

14 Product Service 1-800-522-7658

Original instructions

Never lift the lid if the block is moving. Samples may splash 

out.

Ne jamais soulever le couvercle si le bloc est en mouvement. Les 

échantillons peuvent gicler.

Never operate the RapidVap without the sample block securely 

fastened in place. Excessive vibration will occur.

Ne jamais faire fonctionner le RapidVap sans le bloc 

d'échantillon fixé solidement en place. Des vibrations excessives 

se produira.

Never attempt to reach into the chamber if the block is moving.

Ne jamais tenter de mettre la main dans la chambre si le bloc

est en mouvement.

!

Nut or guide rods – 3 required

Washer – 3 required

Block

Mounting stud

Temperature sensor

Apply heat 

transfer grease
Chapter 3: Getting Started

Product Service 1-800-522-7658 15

Original instructions

Nitrogen Gas Connection

Turn the gas supply off. Install a barb fitting suitable for a 1/4" I.D. hose into the 

“out” port of the regulator. Clamp securely. Alternately, a compression fitting 

may be used that is suitable for a hose with a 3/8" O.D. and 1/4" I.D.

THE NITROGEN PRESSURE MUST NEVER BE ALLOWED 

TO EXCEED 20 PSI. (103 KPA)

Exhaust Port

If the RapidVap N2 is not located in a fume hood, attach one end of the two inch 

diameter venting hose that is supplied with the RapidVap to the exhaust port on the 

right side of the unit. Clamp securely. Route the other end to a fume hood or 

other laboratory ventilation device.

Electrical Connection

Plug the power cord into the receptacle on the back of the RapidVap and plug the 

other end into a suitable wall power receptacle.

Calibrate the Vacuum Sensor

The vacuum sensor can be calibrated to room ambient atmospheric pressure. To 

do this, determine the atmospheric pressure using a known reference device such 

as a mercury barometer. Press and hold the vacuum release button on the 

RapidVap while turning on the RapidVap power switch. Use the increase or 

decrease buttons to make the vacuum display agree with the reference pressure. 

Press run to store the calibration in memory.

Chemical Attack on RapidVap 

Components

Your RapidVap Evaporation System is designed to be chemical resistant to most 

compounds that are commonly used in the concentration processes that are 

performed in it. However, by necessity, the RapidVap is comprised of a number of 

different materials, some of which may be attacked and degraded by certain 

chemicals. The degree of degradation is obviously dependent on the concentration 

and duration of exposure. Some of the major components of the RapidVap that are 

susceptible to degradation are as follows:

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Chapter 3: Getting Started

16 Product Service 1-800-522-7658

Original instructions

C- Moderate Degradation- Questionable Use

D- Severe Degradation- Infrequent use recommended- immediate thorough cleaning required

 If a rotary vane vacuum pump is used, most compounds used in the RapidVap

will degrade the oil if allowed to enter the pump. Generally, a rotary vane 

pump is not suitable for use with the RapidVap.

 Diaphragm vacuum pumps sold by Labconco have wetted parts either made 

from PTFE or protected by PTFE coatings and are suitable for nearly all 

procedures.

 Glass lids are suitable for use with all common compounds. 

When using compounds in the RapidVap that are hostile to the materials of 

construction, it is imperative that the equipment is properly maintained.

 After each run, clean up all residues, spills, and materials that might have 

splashed in the chamber using agents suitable for the substance involved.

 When using a rotary vane pump the oil in the pump should be checked often. It 

must be changed if it is cloudy, shows particles or is discolored. The useful life 

of vacuum pump oil can be extended if the vacuum pump is operated for an 

extended period of time after the RapidVap run is over. This allows 

contaminants to be purged from the hot oil. This must be done with the inlet to 

the pump blocked off to prevent air from free flowing through the pump. If the 

pump is operated at an elevated vacuum level, oil will be expelled from the 

pump and damage will occur.

Acids Bases Solvents

COMPONENT MATERIAL

Acetic Acid 20%

Boric Acid

Formic Acid

Hydrobromic Acid 20%

Hydrochloric Acid 20%

Nitric Acid 20%

Sulfuric Acid 10%

Trifluoroacetic Acid (TFA)

Ammonium Hydroxide

Potassium Hydroxide

Acetone

AcetonitrileChloroform

Dimethyl Formamide

Dimethyl Sulfoxide (DMSO)

Ethanol

Ethyl Acetate

Hexanes

Isoproponal

Methylene Chloride

Toluene

Manifold N2/48 Acetal C C C D D D C D C

Exhaust Elbow N2 Polyamid (Nylon) D D D D D D D C D C

Blower Fan N2 Polyamid (Nylon) D D D D D D D C D C

Exhaust Hose N2 Polyethylene C C C C C C C

Vacuum Fittings Polypropylene C C

Blower Housing N2 Polypropylene C C

Vacuum Hose PVC D C D D D D D D C D D D D

Trim Ring Bromyl Butyl C D D D D D D D

O- Rings Neoprene D D C D D C D D D D D D

Block Hardware Stainless Steel

Nozzle N2 Stainless Steel D D D

Vacuum Sensor Stainless Steel D D D
Chapter 3: Getting Started

Product Service 1-800-522-7658 17

Original instructions

With prudent maintenance your RapidVap will provide years of service. Warranty 

on the effected parts will be void if maintenance has obviously been neglected. If 

you have questions about using specific compounds in your RapidVap, contact 

Labconco Technical Service at 1-800-821-5525 or 816-333-8811 or e-mail 

labconco@labconco.com. 

Solvent Safety Precautions

The RapidVap is not classified as “explosion proof.” It has been designed with 

safety as a primary consideration and should be used in a prudent manner using 

“good laboratory practices.” It has been designed for use with compounds as 

described in the United States National Electrical Code Class I, Group D. The 

block that holds the sample tubes may be programmed to run as hot as 100°C, 

however, the heater element may normally run at 110°C. A thermal fuse limits the 

heater to a maximum temperature of 130°C. It is important that the solvents used 

are compatible with these temperatures. Do not evaporate solvents that have an 

autoignition temperature below 180°C. Do not evaporate solvents that are 

classified as Group A, B, or C by the National Electrical Code. Evaporate only 

non-flammable or Group D solvents with autoignition temperatures 180°C or 

above. Use of other compounds could cause an explosion.

Solvents used in the RapidVap may be flammable or hazardous. 

Use extreme caution and keep sources of ignition away from the 

solvents. When using flammable or hazardous solvents, both 

the RapidVap and the vacuum pump should be operated inside 

a fume hood.

If a sample is spilled in the chamber it must immediately be 

cleaned up.

Hazardous materials such as strong acids or bases, radioactive 

substances and volatile organics, must be handled carefully and 

promptly cleaned up if spilled.

Several components of the RapidVap which are located inside 

the chamber are made of stainless steel which can be attacked 

by acids. Use of acids such as trifluoroacetic acid can result in 

degradation of the product and the vacuum pump if the 

vacuum system is being used. Use care when using aggressive 

liquids which can damage the RapidVap and thoroughly clean 

the RapidVap after each use. Contact Labconco before 

evaporating acids.

WARNING: The disposal of substances used in connection with 

this equipment may be governed by various Federal, State or 

local regulations. All users of this equipment are urged to 

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Chapter 3: Getting Started

18 Product Service 1-800-522-7658

Original instructions

become familiar with any regulations that apply in the user’s 

area concerning 

the dumping of waste materials in or upon water, land or air 

and to comply with such regulations.

AVERTISSEMENT: L'élimination des substances utilisées 

dans le cadre de ce matériel peut être régie par diverses 

réglementations fédérales, provinciales ou locales. Tous les 

utilisateurs de cet équipement sont invités à se familiariser avec 

tous les règlements qui s'appliquent dans le domaine de 

l'utilisateur concernant le déversement de déchets dans ou sur 

l'eau, la terre ou de l'air et de se conformer à ces règlements.

Your Next Step

The installation and setup of your RapidVap is now complete. To learn how to 

load and operate your RapidVap, proceed to Chapter 4: Using Your RapidVap. To 

make a modification to the configuration of your RapidVap, proceed to Chapter 6: 

Modifying your RapidVap. To perform additional diagnostics on your RapidVap, 

proceed to Chapter 7:Troubleshooting. To learn about the maintenance 

requirements for your RapidVap, proceed to Chapter 5: Maintaining Your 

RapidVap.
19 Product Service 1-800-522-7658

Original instructions

CHAPTER 4

USING YOUR RAPIDVAP

After your RapidVap has been installed as detailed in Chapter 3: Getting Started, 

you are ready to begin using your RapidVap. Read this chapter to learn how to:

 set operating parameters.

 operate the controls.

 properly select and position glassware inside your RapidVap.

 understand the display.

 interrupt a cycle after it has begun.

Do not use the RapidVap in a manner not specified by the 

manufacturer (refer to Appendix C: RapidVap Specifications). 

The electrical protection properties of the RapidVap may be 

impaired if the RapidVap is used inappropriately.

Planning

Thoroughly understand procedures and the equipment operation prior to beginning 

work. The unique performance of the RapidVap Vacuum is dependent upon the 

proper balance of heat, vacuum and vortexing action. If the proper balance is not 

established, it is possible to damage or lose a portion of the sample. Therefore, if 

you are unfamiliar with the RapidVap or are attempting a new protocol, it may be 

helpful to make a trial run that is void of the sample you are attempting to 

concentrate.

Select the size of the sample tube so it is compatible with the block. Tubes should 

not be loose in the block. Blocks are available with holes for various size tubes. 

Refer to Appendix D: RapidVap Accessories for available block sizes and pages 19 

and 20 for recommended usable tube volumes and vortex speeds.

!

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Original instructions

The unique performance of the RapidVap N2 is dependent upon the proper balance

of heat, gas flow and vortexing action. If the proper balance is not established, it is 

possible to damage or lose a portion of the sample. Therefore, if you are 

unfamiliar with the RapidVap N2 or are attempting a new protocol, it may me 

helpful to make a trial run that is void of the sample you are attempting to 

concentrate.

Determine if the sample which is to be processed will be allowed to go to dryness 

or whether the evaporation is to cease prior to dryness. If the process should not 

go to dryness, the proper sample tubes must be selected to allow the desired 

amount of solvent to remain in the tubes. Sample tubes are available for various 

end point volumes. Refer to Appendix D: Accessories for available sample tubes. 

Any style ground glass tube may be used if the sample is to go to dryness, 

however, flat bottom tubes evaporate the quickest.

Glassware Selection and Speed Setting 

Guidelines

The speed at which the sample block should oscillate is dependent on the sample 

tube size and the sample volume. Generally, the tube should be no more than half 

full. The faster the speed, the higher the sample will vortex giving a maximum 

surface area and therefore a maximum evaporation rate. However, if the speed is 

too fast, samples will raise above the top of the tube and be lost. Smaller tubes can 

be run faster than larger tubes. The following table gives recommended safe 

speeds for tubes loaded with water. Experimentation with the specific sample may 

determine faster speeds. When setting the speed, keep in mind that the sample will 

raise up slightly in the tube when vacuum is applied to the chamber of the vacuum 

model.

GLASS VIALS USED IN THE RAPIDVAP SHOULD BE OF 

THE STYLE THAT DO NOT HAVE THE BEAD OR LIP ON 

THE TOP EDGE. IF VIALS WITH BEADS ARE USED, THE 

BEADS COULD HIT EACH OTHER AND BREAK THE

GLASS.

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Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 21

Original instructions

Several different size sample blocks are available for the RapidVap Vacuum 

model. The maximum recommended sample volumes and vortex speeds are as 

follows:

TUBE

SIZE

SAMPLE

VOLUME

VORTEX 

SPEED

12 x 75 mm (6 ml) 3 ml 95%

13 x 100 mm (10 ml) 5 ml 95%

16 x 150 mm (23 ml) 12 ml 95%

15 ml centrifuge 7.5 ml 66%

28 mm (46 ml) 23 ml 48%

600 ml 50 ml 45%

100 ml 45%

200 ml 38%

300 ml 29%

400 ml 20%

450 ml 18%

TUBE

SIZE

SAMPLE

VOLUME

VORTEX 

SPEED

170 ml 50 ml 50%

75 ml 47%

100 ml 42%

125 ml 35%

Two sample blocks are available for the RapidVap N2. Recommended speeds are 

as follows:

TUBE

SIZE

SAMPLE

VOLUME

VORTEX 

SPEED

600 ml 50 ml 90%

100 ml 90%

200 ml 76%

300 ml 58%

400 ml 40%

450 ml 36%

170 ml 50 ml 100%

75 ml 95%

100 ml 85%

125 ml 70%

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Original instructions

Four sample blocks are available for the RapidVap N2/48. Recommended speeds 

are as follows:

TUBE

SIZE

SAMPLE

VOLUME

VORTEX 

SPEED

12 mm (6 ml) 3 ml 100%

13 mm (10 ml) 5 ml 100%

16 mm (23 ml) 12 ml 100%

20 mm (35 ml) 18 ml 100%

Loading Glassware Into the RapidVap

Smooth operation of the RapidVap is dependent upon proper balance of the 

machine. Therefore, if less than a full load of samples is run, it is important to 

load samples into the RapidVap in a fairly uniform manner distributing the weight 

of the samples and glassware evenly in the sample block.

IN ORDER TO MAXIMIZE THE PERFORMANCE OF THE 

RAPIDVAP IT IS IMPORTANT THAT SOME OF THE 

SAMPLES ARE CLUSTERED AROUND THE FRONT LEFT 

HAND BLOCK MOUNTING STUD. THE BLOCK 

TEMPERATURE SENSOR IS LOCATED ADJACENT TO THIS 

BLOCK MOUNTING STUD. BY POSITIONING THE SAMPLE 

NEAR THE SENSOR, THE SENSOR WILL DETECT THE 

COOLING EFFECT OF THE EVAPORATING SAMPLES AND 

SIGNAL THE CONTROLS TO SUPPLY MORE HEAT TO THE 

SAMPLE BLOCK.

The best evaporation rate is achieved under conditions that maximize sample 

surface area. These include using the largest tube possible, and using the highest 

vortex speed possible.

When less than 8 samples are run in the RapidVap N2 or less than 48 samples are 

run in the RapidVap N2/48, nitrogen flow can be directed to 2, 4, or 6 positions. It 

is important to position glassware properly in the RapidVap N2 when less than a 

full block is run to ensure that nitrogen gas is directed downward where the sample 

is located. Note the label on the hub in the center of the chamber. This indicates 

which nozzles on a RapidVap N2 or nozzle clusters on a RapidVap N2/48 will be 

activated. If one or two positions are to be run, samples must be positioned at 

locations identified (2). If three or four positions are to be run, samples must be 

positioned at locations identified (4). If five or six positions are to be run, samples 

must be positioned at locations identified (6). If seven or eight positions are to be 

run, samples may be positioned at any of the locations. When using the RapidVap 

N2/48, glassware may be placed anywhere within the activated cluster of nozzles.

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Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 23

Original instructions

Heat Setting Guidelines

The evaporation rate achieved by the RapidVap is dependent upon a variety of 

factors. These include the nature of the solvent, the temperature, the pressure in 

the vacuum system or the flow of the nitrogen gas in the RapidVap N2, the volume 

of sample, shape of tubes and vortex speed. Because of the multiplicity of factors 

it is impossible to give “typical” performance data.

By design, the RapidVap Vacuum model can be run at lower temperature settings 

than the RapidVap N2 model. This is because the decrease in pressure will cause 

the sample to evaporate at a lower temperature. As a general guideline, to speed 

the evaporation process, the RapidVap temperature should be set as high as 

possible as long as the temperature will not damage the sample or cause the sample 

to bump.

In the RapidVap Vacuum models, generally the evaporation rate will be optimized 

with the block temperature set and preheated 20 to 40°C above the boiling point of 

the solvent at the operating pressure.

For example, methanol (which boils at 65°C at atmospheric pressure) boils at 5°C 

at pressure of 53 mBar. Under these vacuum conditions, the block temperature 

should be set between 25 to 45°C. The nomogram and equation to follow will help 

in this determination.

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Chapter 4: Using Your RapidVap

24 Product Service 1-800-522-7658

Original instructions

Calculating the boiling point:

The operating pressure corresponding to the desired boiling point temperature may 

be calculated for any solvent using the following formula:

log P = 2.8811 – Ta – T

 (b)(T)

Where P = Vacuum (mm Hg)

Ta = Boiling Point Temperature at Atmospheric

 Pressure (°K)

T = Desired Boiling Point Temperature (°K)

b = Constant from Table

Useful conversion factors:

1 mBar = .75 mm Hg

°K = °C + 273

Using the nomogram:

To use this graph, three facts must be known about a given solvent:

1. Boiling point at normal atmospheric pressure (1 Bar).

2. Constant b.

3. Either operating temperature or operating pressure.

To determine the desired boiling point at a given pressure:

1. Find the boiling point at normal atmospheric pressure (1 Bar) on the left side of 

the graph.

2. Find the operating pressure on the right side of the graph.

3. Draw a straight line linking these two points.

4. Find “Constant b” for the solvent on the top of the grid. Follow that line until 

it intersects with the line as drawn between the two points. This point 

represents the boiling point at the given pressure and the temperature is read 

off the left or right side of the grid (0-250°C).

To determine the operating pressure necessary to achieve a given boiling 

point:

1. Find the boiling point at normal atmospheric pressure (1 Bar) on the left side of 

the graph.

2. Find the “Constant b” and follow this line to the desired boiling point on the 

grid (0-250°C).

3. Draw a straight line linking these two points and extrapolate on the right hand 

scale to find the operating pressure.
Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 25

Original instructions

SOLVENT

BOILING 

PT (°C)

DENSITY 

(g/cm3)

HEAT OF 

VAPORIZATION 

(Kcal/Kg) CONSTANT b

VACUUM FOR 

BOILING POINT 

AT 40°C (MBAR)

Acetone 56 .790 125 0.196 556

Acetonitrile 82 .786 178 0.195 208

Acetylene tetrachloride 147 1.602 53 0.200 20

Benzene 80 0.879 93 0.202 236

Butyl alcohol 118 0.810 120 0.156 26

Carbon tetrachloride 77 1.594 45 0.206 271

Chlorobenzene 132 1.110 90 0.202 36

Chloroform 60 1.480 59 0.203 474

1.2 Dichloroethane 83 1.235 126 0.201 210

Dichloroethylene 55 1.250 41 0.200 584

Diproplyether 68 0.726 76 0.207 375

Dioxide 111 1.034 98 0.195 70

Ethyl acetate 77 0.900 102 0.189 240

Ethyl alcohol 78 0.791 205 0.159 175

Ethylene dichloride 85 1.256 78 0.200 194

Heptane 98 0.680 74 0.200 120

Hexane 69 0.659 85 0.206 360

Iso-amyl alcohol 132 0.800 120 0.160 15

Iso-butyl alcohol 108 0.803 120 0.160 44

Isopropyl alcohol 82 0.785 160 0.158 136

Methyl alcohol 65 0.792 267 0.167 337

Methylene chloride 40 1.325 41 0.194 1013

Methyl ethyl ketone 80 0.810 113 0.206 243

N-Amyl alcohol 137 0.814 142 0.158 11

Pentachloroethane 159 1.700 45 0.207 15

Pentane 36 0.626 85 0.214 1013

Propyl alcohol 97 0.804 165 0.154 67

Tert, Butanol 83 0.787 141 0.154 130

1, 1, 2, 2, 

Tetrachloroethane

146 1.603 60 0.198 20

Tetrachloroethylene 121 1.624 50 0.202 53

Toluene 111 0.867 86 0.202 76

1, 1, 1, Trichloroethane 74 1.346 76 0.206 301

Trichloroethylene 87 1.462 57 0.202 183

Water 100 1.000 540 0.167 72

Xylene 140 0.870 82 0.199 25

Physical constants:
Chapter 4: Using Your RapidVap

26 Product Service 1-800-522-7658

Original instructions

Determination of Operating Conditions

Applied Vacuum/Boiling Point:

ts = Boiling point at 1 bar (normal pressure)

tp = Boiling point at P mbar (operating pressure)

p = Operating pressure in mbar

Example methyl alcohol:

1. Boiling point at normal (1 bar) atmospheric pressure = 65°C.

2. Constant b = 0.160

3. Operating pressure = 130 mBar

4. Boiling point at 130 mBar pressure = 24°C
Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 27

Original instructions

Constant b Groups

0.200 Aliphatic hydrocarbons

Aliphatic halogenated hydrocarbons

0.195 Aromatic hydrocarbons

Aromatic halogenated hydrocarbons

Ketones

Ethers

Nitriles

Heterocyclic compounds

0.190 Aldehydes

Esters

0.185 Amines

0.180 Phenols

0.165 Acids

0.160 Alcohols

Time Setting Guidelines

It is often desirable to stop the concentration process before the solvent is entirely 

evaporated. This is accomplished by using glassware that has a small diameter 

stem on the bottom and using the “Time” function to shut off the process after a 

predetermined interval of time.

The “Cool Zone” feature is available on the RapidVap N2 with 8 places and is not 

available on the RapidVap N2 with 48 places.

The design of the RapidVap N2 causes the evaporation to proceed quickly when 

the sample is in the larger upper chamber of the sample tubes. When the solvent 

evaporates sufficiently to drop the level into the smaller stem, the evaporation rate 

decreases significantly. This phenomenon allows the solvent in all sample tubes to 

evaporate out of the large upper chamber before any of the small chambers are 

completely evaporated dry providing that all sample tubes are filled with nearly the 

same starting volumes.

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Chapter 4: Using Your RapidVap

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Original instructions

When it is necessary to end the concentration process with the sample still 

dissolved in a small amount of solvent, the time function should be activated and 

the process time set to allow the solvent sufficient time to evaporate completely 

out of the large upper portion of the sample tube and into the small lower portion 

“Cool Zone.” This time can be approximated by knowing the starting sample size, 

the desired end point volume, the stem size of the sample tube used and the 

solvent. The tables in Appendix C: RapidVap Specifications indicate the 

approximate time required to evaporate various common solvents. Actual times 

must be determined by the user. When the set time has expired, the RapidVap N2

will give an audible alarm and turn off all RapidVap functions.

The tables in Appendix C: RapidVap Specifications indicate approximate times 

required to evaporate various common solvents. Actual times must be determined 

by the user. The RapidVap can be set to alarm after a preset period of operation. 

When the time expires, the RapidVap will give an audible alarm and turn off all 

functions.

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Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 29

Original instructions

RapidVap Controls

The control panel for the RapidVap vacuum model and the RapidVap N2 are 

shown below with a description about their function.

RapidVap Vacuum Model

RapidVap N2 Model

1. Display – The liquid crystal display (LCD) shows set point parameters and 

actual measured conditions.

1

2

4

6

7

3

5

1

6

5 4

3

2
Chapter 4: Using Your RapidVap

30 Product Service 1-800-522-7658

Original instructions

2. Set Point Select Button – To select a parameter to change, press the set point 

select button directly below the parameter.

3. Run/Stop Button – Used to start or stop a run.

4. Decrease Button – When pressed, the last selected set point will decrease.

5. Increase Button – When pressed, the last selected set point will increase.

6. Preheat Button – Used to turn on the heaters to preheat the sample block prior 

to loading samples. When pressed during a run, it will switch the end point 

alarm from audible to muted or back to audible. The audible alarm is the 

default mode when the RapidVap is powered up.

7. Vacuum Release (Vacuum Model Only) – When pressed and held, the vacuum 

valve will open to break vacuum. This is used to quickly decrease vacuum 

should bumping of the sample occur.

Operating The RapidVap Controls

Preheat:

To preheat the chamber, press the preheat button. The LED next to the button will 

illuminate and the display will show:

SP: XXC ACT: XXC

Press increase or decrease buttons until the desired set point is displayed. The 

actual block temperature will be displayed to the right. When power is being 

supplied to the heaters, a bar under the actual temperature will illuminate. The 

block will continue to preheat until either the preheat button is pressed again or the 

run button is pressed.

Select existing program:

Operating parameters can be stored in memory so protocols can be repeated. Nine 

programs can be stored. To select a program, press the set point select button 

directly under the word “PROG.” An arrow will point to the current program 

number indicating that this set point can be altered. To change the program 

number, press the increase or decrease button until the desired program number is 

displayed. When the program number is changed, all its set points will change 

also to indicate the last entered parameters. Pressing the “PROG” set point button 

will reset the timer to the previous set point time.

Change speed set point:

To change the speed set point parameter, press the set point select button directly 

under the word “SPEED.” Arrows will point to the present set point. The speed 

may be altered from 0 to 100% by pressing the increase or decrease buttons. The 

last entered set point will be stored in memory.
Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 31

Original instructions

It is suggested that the user set the vortex speed at a low percentage and gradually 

increase it after the run is started. This will minimize the possibility of samples 

sloshing out of the tubes. Reruns of the same protocol may start at the speed 

determined by previous runs.

Change heat set point:

To change the heat set point, press the set point select button under the word 

“HEAT.” Arrows will point to the present set point which can be changed from

-- (OFF) up to 99° by pressing the increase or decrease buttons. The set point is 

100°C if the display shows “HI.” The last entered set point will be stored in 

memory.

Change time set point:

To change the time set point, press the set point select button under the word 

“TIME.” Arrows will point to the present set point which can be changed from 1 

to 999 minutes by pressing the increase or decrease buttons. If it is desired to have 

the RapidVap run continuously without alarming at the end of a time period, press 

the increase button until the display says “RUN.” The last entered set point will be 

stored in memory.

To reset the timer to the previous set point time, the “PROG” set point button must 

be pressed.

Change the Vacuum set point (Vacuum model only): 

To change the vacuum set point, press the set point select button directly under the 

word “VACUUM.” An arrow will point to the last entered vacuum set point. The 

vacuum level may be set between 0 to 999 mBar by pressing the increase or 

decrease buttons. Above 999 mBar, the display will show “HI.” With a “HI” 

setting, the vacuum pump will not operate. The last entered set point will be stored 

in memory. Keep in mind that even though a deep vacuum set point may be 

entered, the actual vacuum level that the RapidVap will try to maintain can be no 

deeper than the vacuum level that the vacuum pump can maintain.

Select the number of samples that will be run (RapidVap N2 only):

Press the set point select button under the word “SAMPLE.” An arrow will point 

to the last entered set point. By pressing the increase or decrease button, the 

number of samples or clusters may be changed from 2 to 4 to 6 to 8. When 

running less than eight samples in the RapidVap N2 or 48 samples in the RapidVap 

N2/48, be sure to position them as described in the previous paragraph “Loading 

Glassware Into the RapidVap.”

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Original instructions

Operating The RapidVap

Never lift the lid if the block is moving. Samples may splash 

out.

Ne jamais soulever le couvercle si le bloc est en mouvement. Les 

échantillons peuvent éclabousser.

Never attempt to reach into the chamber if the block is moving.

Ne jamais tenter de mettre la main dans la chambre si le bloc 

est en mouvement.

Keep hands clear of lid at all times and do not place objects on 

the lid. Upon power up the unit may resume an interrupted 

program and the lid may start moving.

Gardez les mains éloignées de couvercle à tout moment et ne 

pas placer d'objets sur le couvercle. Dès la mise sous tension 

l'appareil peut reprendre un programme interrompu et le 

couvercle peut commencer à bouger.

1. Turn the power switch ON.

2. Select a program or set the set point parameters.

3. Turn on the nitrogen (RapidVap N2 only).

4. Preheat the block if desired.

5. Place samples in vials. Normally the vials should be no more than half full.

6. Load sample vials in the chamber.

7. Close the lid. On RapidVap N2/48 models, press down and rotate the cross bar 

on the top of the lid counter clockwise approximately 1/8".

8. Swing both latches over the lid and tighten both knobs. Do not over tighten.

9. Press RUN. If the display was showing set point parameters, it will change to 

show actual parameters. Press “RUN” again. The “S” (STOP) in the display 

will change to “R” (RUN).

10. Set point parameters can be altered at any time during a run by first selecting 

the parameter using the appropriate set point select button and then pressing 

the “Increase” or “Decrease” switch.

11. If the time set point is used, at the end of the set time an alarm will sound. All 

operating functions will cease.

12. Press STOP to terminate operation if the RapidVap has not already stopped 

itself.

13. When the evaporation is complete, allow the chamber to stop moving, unlatch 

the latches, on the RapidVap N2/48 models rotate the cross bar clockwise 

approximately 1/8", lift the lid and remove the samples.

!
Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 33

Original instructions

14. Any time the RapidVap is not in operation, the power switch should be turned 

OFF. This will prolong the life of the cooling fan and the blower in the 

RapidVap N2.

Operational Notes

The LCD display conveys various pieces of information. When the RapidVap is 

turned on, the RapidVap will return to the same mode (RUN or STOP) that it was 

in when the power was turned off. If the RapidVap was in the RUN mode when 

the power was turned off, when the power is turned on, the RapidVap will attempt 

to return to the programmed set points.

If the previous run is to be duplicated, it is important to press the program set point 

button prior to pressing run. This will show all the set points for that program and 

will reset the timer back to the programmed set point. Without pressing the 

program set point button, the time will not be reset and will continue to count 

down from the time at which it was stopped.

Interrupting a Cycle After it Has Begun

At any time during a run, the cycle may be stopped by pressing the STOP button. 

This shuts off all operating functions. After the chamber stops oscillating, the 

latches may be unlatched and the lid opened. If it is necessary to re-start the 

RapidVap, close the lid and secure the latches and press RUN. The RapidVap will 

resume operation at the same set point parameters and the timer will continue to 

count down from the time at which the RapidVap was stopped.

End Alarms

The RapidVap has two means to signal the completion of a run. The first method is 

determined by the operator when the run time is set as described in the previous 

paragraph, Time Setting Guidelines. In the second method the RapidVap will 

automatically sense when an evaporation process is nearly complete by comparing 

temperatures in the unit. When the RapidVap detects end point, it will sound an 

alarm and the LED next to the “PREHEAT/ END ALARM” button will flash. This 

alerts the operator to closely monitor the run’s completion. This method performs 

best when large samples are processed at high temperatures. When small samples 

or low temperatures are used, the alarm may signal prior to the end of evaporation. 

The audible alarm may be canceled by pressing the “PREHEAT/ END ALARM” 

button. The LED will continue to flash until the “STOP” button is pressed. If the 

button is pressed again, the audible alarm will become active again.
Chapter 4: Using Your RapidVap

34 Product Service 1-800-522-7658

Original instructions

RS-232 Communications

Some RapidVaps are equipped with RS-232 communications capabilities. This 

hardware and software allows a user to perform all the front panel functions from a 

standard RS-232 link. Communications will be at 4800 baud, no parity, 8 bit 

word, 1 stop bit, and a 3-wire interface (TXD, RXD and circuit common). The 

RS-232 link will be duplex or two-way, that is, it will allow the RapidVap Basic 

and N2 models to be controlled externally (incoming commands) as well as 

provide status information coming out of the RapidVap (outgoing status). All 

communications will be done in standard ASCII format using the programming 

syntax below.

RS-232 Programming Syntax

The RapidVap only responds to commands sent by the connected computer or 

terminal – it does not send out commands on its own. The programming syntax 

has two forms:

1. # [command abbreviation letter] [value]; when the command requires a 

numeric value.

2. # [command abbreviation letter ]; when the command does not require a 

numeric value.

When the programming syntax contains a numeric value, it will change the 

operation of the RapidVap. When the programming syntax does not contain a 

numeric value, the RapidVap will respond with its current status for that command 

value.

Note that the lead-in character is “#” while the “[ ]” (brackets) are shown only to 

separate parameters for ease of understanding. These brackets will not be used in 

the actual ASCII command string. Finally, the “;” is used to indicate the end of a 

command. Also note that ‘\n’ indicates a newline character.

#R[x]; x=0 for stop, x=1 for run and x=2 for pre-heat, will get a x’\n’ 

response for confirmation; when a “#R;” with no “[x]” is sent, 

the RapidVap will respond 0, 1 or 2

#S[xxx]; Selects the vortex speed of program 9 from 0% or 12% to 

100%, will get a xxx;yyy’\n’ response for confirmation. 

(xxx:speed setpoint, yyy:actual speed)

#T[xxx]; Selects the HEAT TEMPERATURE SET POINT of program 9 

from 30 to 100 (C), will get a xxx;yyy’\n’ response for 

confirmation. (xxx:temperature setpoint, yyy:actual 

temperature); by entering “#T0;”, the heat will be set to OFF
Chapter 4: Using Your RapidVap

Product Service 1-800-522-7658 35

Original instructions

#t[xxxx] Selects the TIME SET POINT of program 9 from 1 to 999 

minutes, and 1000 for no stopping (will run continuously), will 

get a xxxx;yyyy’\n’ response for confirmation. (xxxx:time 

setpoint, yyyy:time left)

#V[xxxx]; Selects the VACUUM SET POINT (if the RapidVap is a 

Vacuum model) of program 9 from 1 to 1000 mBar, will get a 

xxxx;yyyy’\n’ response for confirmation. (xxxx:vacuum 

setpoint, yyyy:actual vacuum)

#H[xxx]; Selects the PRE-HEAT SET POINT of program 9 from 30 to 

100 C, will get a xxx;yyy’\n’ response for 

confirmation.(xxx:pre-heat setpoint, yyy:actual temperature)

#L[x]; KEY LOCKED when x=1 and UNLOCKED when x=0, will 

get a x’\n’ response for confirmation

#N[x] elects the N2 VALVES (if the RapidVap is an N2 model) of 

program 9 from 0,2,4,6,8, will get a x’\n’ response for 

confirmation 

#M[x]; x=1 will mute the audio alarm; x=0 will allow the audio alarm 

to work normally

#E; The RapidVap will respond to this command with a numeric 

value as follows :’”1"’=indicates an endpoint has been reached; 

“0”=endpoint has not been reached

#e; The RapidVap will respond to this command with a numeric 

value as follows: 0=all functions are normal; “1”=lid is open; 

“2”=communication problem; “3” and later numbers will be 

established later as specific error messages

Note: When controlling the RapidVap using the RS-232 link, all control parameters 

will be entered into program 9.

Note: All of the above commands can be sent with no numeric value, that is 

‘#[command];’ (without value) to read out the setpoint and actual value without 

changing the setpoint.

Note: There is no command for the vacuum release button on the front panel since 

this button is momentary in nature – the “#V0000;” command will bleed the 

vacuum chamber to atmospheric pressure.

Note: The above commands can be sent at a maximum rate of one command per 

second.
Chapter 4: Using Your RapidVap

36 Product Service 1-800-522-7658

Original instructions

RS-232 Hardware Required

The connecting cable, Labconco #7484800 is supplied with the unit and is wired as 

shown below.
37 Product Service 1-800-522-7658

Original instructions

CHAPTER 5

MAINTAINING YOUR

RAPIDVAP

Under normal operation, the RapidVap requires little maintenance. The following 

maintenance schedule is recommended:

As needed:

1. Clean up all spills; remove liquids from chamber.

2. Clean lid and gasket using soft cloth, sponge or chamois and a mild, nonabrasive soap or detergent.

Weekly:

1. If the vacuum pump contains oil, check the condition and level. If the oil level 

is low, add oil. If the oil contains excessive amounts of moisture, detected by a 

cloudiness in the oil, it will be necessary to change the oil. For further 

information regarding procedures for changing the vacuum pump oil, refer to 

the vacuum pump manufacturer’s instructions. To expel small amounts of 

water that may have accumulated in the pump oil, periodically operate the 

vacuum pump against a dry, leak-tight system. The gas ballast must be open. 

Monthly:

1. The rubber components on the RapidVap may eventually deteriorate and 

require replacement. The effective life of rubber parts depends upon both their 

usage and the surrounding environment. Check all rubber hoses and gaskets 

and replace any that show signs of hardening, permanent set or deterioration.

2. Using a soft cloth, sponge or chamois and a mild, non-abrasive soap or 

detergent, clean the glass lid.

V
Chapter 5: Maintaining Your RapidVap

38 Product Service 1-800-522-7658

Original instructions

3. Using a soft cloth, sponge, or chamois and a mild, non-abrasive soap or 

detergent, clean the exterior surfaces of the unit. Liquid spray cleaners and 

polishes may be used on the exterior surfaces. Do not use solvents to remove 

stains from the exterior surfaces as they may damage the finish.

4. All weekly activities.
39 Product Service 1-800-522-7658

Original instructions

CHAPTER 6

MODIFYING YOUR RAPIDVAP

The configuration of your RapidVap may need to be changed to accommodate 

your needs. For example, you may want to change the sample size you are running 

so you will need to change the block or you may want to add a lid heater to 

eliminate condensation inside the lid. Read this chapter to learn how to:

 change blocks.

 install a lid with heater.

Changing the Sample Blocks

If it is necessary to change from one sample size to another, it may be necessary to 

change the block. Refer to Appendix D: RapidVap Accessories for available 

sample blocks.

First, using a 7/16" socket (RapidVap Vacuum and RapidVap N2), remove the 

three nuts and washers on the top of the existing block. The RapidVap N2/48 

requires a 9/16" socket to remove the three manifold guides that secure the block. 

Lift the block out of the chamber. Note the asymmetric hole pattern of the three 

mounting holes. Apply a small amount of heat transfer grease supplied with the 

RapidVap to the end of the temperature sensor probe that extends up from the 

bottom of the chamber.

Position the block over the three studs in the chamber. Install the flat washers and 

nuts or manifold guide rods. Tighten securely.
Chapter 6: Modifying Your RapidVap

40 Product Service 1-800-522-7658

Original instructions

Installing the Optional Lid Heater

If a Lid Heater is to be added by the user, first disconnect the main power cord to 

the RapidVap. Then remove the existing lid by removing the two screws that hold 

either the RH or LH hinge pivot support bracket. Remove the bracket and then 

slide the lid assembly off of the other bracket. Install the new lid with the heater 

attached by reversing the process. Plug the jack attached to the lid heater into the 

receptacle on the back of the RapidVap. The lid heater will operate any time the 

main power switch is on.

V
41 Product Service 1-800-522-7658

Original instructions

CHAPTER 7

TROUBLESHOOTING

Refer to the following if your RapidVap fails to operate properly. If the suggested 

corrective actions do not solve your problem, contact Labconco for additional 

assistance. The following failure codes may appear on the display when problems 

are sensed by the internal self check routine.

DISPLAY 

ERROR CODE

CAUSE CORRECTIVE ACTION

Top Temp Sensor Top sensor failure Replace top sensor assembly.

Connection failure Repair connection.

Bottom Temp 

Sensor

Bottom sensor 

failure

Replace bottom sensor assembly.

Connection failure Repair connection.

Vacuum Sensor Sensor failure Replace sensor assembly.

Connection failure Repair connection.

Lid Opened Lid open Close lid.

Switch failure Replace switch.

Connection failure Repair connection.
Chapter 7: Troubleshooting

42 Product Service 1-800-522-7658

Original instructions

DISPLAY 

ERROR CODE

CAUSE CORRECTIVE ACTION

Mem Fail – Push 

Prog

Memory failure Push program button.

New memory IC 

chip

Push program button.

Bad memory IC 

chip

Call Labconco – Replace IC chip or control 

PCB.

Motor Error Stalled condition Turn power off. Try to restart after one 

minute. Call Labconco if error message 

remains.

Excessive speed 

detected, i.e. >120%

Turn power off. Try to restart after one 

minute. Call Labconco if error message 

remains.

Defective motor Turn power off. Try to restart after one 

minute. Call Labconco if error message 

remains.

Other corrective actions for potential problems are as follows:

PROBLEM CAUSE CORRECTIVE ACTION

Unit will not 

operate

Unit not connected to 

electrical power

Connect unit to proper electrical 

receptacle.

Circuit breaker blown Correct electrical problem and reset 

circuit breaker by pressing button.

Lid open Close lid.

Excessive 

vibration

Sample tubes not 

located symmetrically 

in block

Reposition sample tubes.

Sample block loose Tighten all three mounting screws.

Sample block not 

installed

Install sample block.

Sample odor in 

lab

Vent hose exhausting 

into lab area

Redirect hose to fume hood.

Inoperable blower 

(RapidVap N2)

Replace blower.
Chapter 7: Troubleshooting

Product Service 1-800-522-7658 43

Original instructions

PROBLEM CAUSE CORRECTIVE ACTION

Sample in 

bottom of 

chamber

Gas pressure too high 

(RapidVap N2)

Reduce pressure. 

Vortex speed too high Reduce speed.

Condensation forming 

inside lid (RapidVap 

Vacuum)

Install lid heater. See page 36.

Poor recovery 

rates

Sample going to 

dryness (RapidVap N2)

Program RapidVap N2 to prevent dryness.

Sample sloshing out of 

tube

Decrease vortex speed.

Heat setting is too high Decrease heat.

Evaporation

rate is reduced

Gas supply depleted 

(RapidVap N2)

Replenish gas.

Heater inoperable Contact Labconco.

Vacuum pump failure 

(RapidVap Vacuum)

Check pump.

No vacuum 

poor vacuum 

(RapidVap 

Vacuum)

Pump not on Turn on pump.

Control valve open Check control valve.

Leaks in lines or 

connectors

Locate and repair.

Foreign material on lid 

gasket

Clean gasket and lid.

Vacuum pump oil low Add oil.

Excessive 

contamination in 

vacuum pump oil

Replace oil.

Pump not connected to 

RapidVap

Connect hose and power cord.
Chapter 7: Troubleshooting

44 Product Service 1-800-522-7658

Original instructions

PROBLEM CAUSE CORRECTIVE ACTION

No gas flow 

(RapidVap N2)

Gas depleted Install new supply of gas.

Sample position not 

activated

Activate position per page 30.

Nozzle clogged Unplug nozzle with fine wire.

Valve inoperable Contact Labconco

Gas flows 

continuously

Valve inoperable Contact Labconco

Control inoperable Contact Labconco
45 Product Service 1-800-522-7658

Original instructions

APPENDIX A

RAPIDVAP VACUUM AND

RAPIDVAP N2 COMPONENTS

The following pages list components that are available for your RapidVap. The 

parts shown are the most common replacement parts. If other parts are required, 

contact Product Service.
Appendix A: RapidVap Vacuum & RapidVap N2 Components

46 Product Service 1-800-522-7658

Original instructions

Item Quantity Part No. Description

1 1 13023-00 Switch, Power

2 4 74953-00 Foot

3 1 79167-00 Fan Cooling

4 1 74838-00 PCB, Main (RapidVap Vacuum)

4A 1 74838-03 PCB, Main (RapidVap N2 & RapidVap N2/48)

4B 1 74838-04 PCB, Main (RapidVap Vacuum w/RS232)

4C 1 74838-05 PCB, Main (RapidVap N2 & RapidVap N2/48 w/ RS232)

5 8 74887-00 Isolator, Upper

6 8 74915-00 Isolator, Lower

7 1 13364-00 Cord, Power (115V)

7A 1 13365-00 Cord, Power (230V)

8 1 12926-00 Triac

9 1 79176-00 Diode Bridge

10 1 78252-00 Belt

11 1 12111-00 Motor

-- 1 13444-06 Fuse, 12A, Type T, Slow Blow (Not Shown)

RapidVap Vacuum and RapidVap N2 Components
Appendix A: RapidVap Vacuum & RapidVap N2 Components

Product Service 1-800-522-7658 47

Original instructions

1

2

3

4

5

6

7

8

9

11

10
Appendix A: RapidVap Vacuum & RapidVap N2 Components

48 Product Service 1-800-522-7658

Original instructions

Item Quantity Part No. Description

21 1 74917-00 Temperature Sensor, Lower

22 1 74870-00 Temperature Sensor, Upper

23 1 74916-00 Vacuum Sensor

24 2 74882-00 Spring, Latch

25 2 74880-00 Latch

26 6 19271-05 Washer, Latch

27 2 74883-00 Knob, Latch

28 3 19092-21 Nut, Block

29 3 19116-00 Washer, Block

30 3 79046-01 Stud, Block

31 1 74979-00 Trim Ring

32 1 15532-00 Hose, Exhaust

33 1 74847-00 Shield, Lid

34 1 74846-00 Lid

34A 1 74844-00 Lid With Heater

35 1 79759-01 Thermal Fuse

36 1 73449-00 Valve, Vacuum

37 1 74920-02 PCB, Display/Control

38 1 74926-00 Label, Control Panel

39 1 13061-00 Relay, Vacuum Pump

-- 1 Fuse, Main Vacuum PCB, 2A, Type T, Slow Blow 

(Not Shown)

RapidVap Vacuum Components
Appendix A: RapidVap Vacuum & RapidVap N2 Components

Product Service 1-800-522-7658 49

Original instructions

26

34

33

32

31

30

35

28

29

27

25

24

23

22

21

39

36

37 38
Appendix A: RapidVap Vacuum & RapidVap N2 Components

50 Product Service 1-800-522-7658

Original instructions

Item Quantity Part No. Description

51 1 74917-00 Temperature Sensor, Lower

52 1 74870-00 Temperature Sensor, Upper

53 2 74882-00 Spring, Latch

54 2 74880-00 Latch

55 6 19271-05 Washer, Latch

56 2 74883-00 Knob, Latch

57 3 19092-21 Nut, Block (RapidVap N2)

57A 3 74488-00 Guide Stud (RapidVap N2/48)

58 3 19116-00 Washer, Block

59 3 79046-01 Stud, Block

60 1 74845-00 Lid (RapidVap N2)

60A 1 74497-00 Lid (RapidVap N2/48)

61 1 74979-00 Trim Ring

62 1 79131-01 Hose, Exhaust Short

63 1 74889-01 Valve Assembly, Nitrogen

64 1 79131-02 Hose Exhaust Long

65 1 79096-00 Blower, Exhaust

66 1 74920-02 PCB, Display/Control

67 1 74922-00 Label, Control Panel

68 1 79759-01 Thermal Fuse

-- 1 13444-03 Fuse, Exhaust Blower, 4A, Type T, Slow Blow 

(Not Shown)

RapidVap N2 and RapidVap N2/48 Components
Appendix A: RapidVap Vacuum & RapidVap N2 Components

Product Service 1-800-522-7658 51

Original instructions

67 66 51 65

64

63

62

68

61

58

60A

59

53

56

54

52

57A

59

58

57

55
Product Service 1-800-522-7658 52

Original instructions

APPENDIX B

RAPIDVAP DIMENSIONS

RapidVap Vacuum
Appendix A: RapidVap Vacuum & RapidVap N2 Components

Product Service 1-800-522-7658 53

Original instructions

RapidVap N2
Product Service 1-800-522-7658 54

Original instructions

APPENDIX C

RAPIDVAP SPECIFICATIONS

This Appendix contains technical information about the RapidVap including 

specifications, environmental operations conditions, wiring diagrams and 

evaporation rates.

Electrical Specifications

 Nominal amperage for 115V RapidVap Vacuum (model 79000-00 & 

79000-10) excluding vacuum pumps: 8A

Maximum amperage with vacuum pump: 16A 

 Nominal amperage for 230V RapidVap Vacuum (model 79000-01 & 

79000-11) excluding vacuum pumps: 4A

Maximum amperage with vacuum pump: 8A 

 Nominal amperage for 115V RapidVap Vacuum (model 79000-02 & 

79000-12) with Lid Heater excluding vacuum pump: 8.6A

Maximum amperage with vacuum pump: 16A 

 Nominal amperage for 230V RapidVap Vacuum (model 79000-03 & 

79000-13) with Lid Heater excluding vacuum pump: 4.3A

Maximum amperage with vacuum pump: 8A

 Nominal amperage for 115V RapidVap N2 (model 79100-00, 79100-10, 

79100-12 & 79100-14): 8A

 Nominal amperage for 230V RapidVap N2 (model 79100-01, 79100-11, 

79100-13 & 79100-15): 4A 

 Frequency (all models): 50/60 Hz

 Phase: Single

 Heater power: 1000 watts

 Lid heater power: 40 watts

Environmental Conditions

 Indoor use only.

 Maximum altitude: 6562 feet (2000 meters).

 Ambient temperature range: 41° to 104°F (5° to 40°C).

 Maximum relative humidity: 80% for temperatures up to 88°F (31°C), 

decreasing linearly to 50% relative humidity at 104°F (40°C).

 Main supply voltage fluctuations not to exceed ±10% of the nominal 

voltage.
Appendix C: RapidVap Specifications

Product Service 1-800-522-7658 55

Original instructions

 Transient overvoltages according to Installation Categories II (Overvoltage 

Categories per IEC 1010). Temporary voltage spikes on the AC input line 

that may be as high as 1500V for 115V models and 2500V for 230V 

models are allowed.

 Used in an environment of Pollution degrees 2 (i.e., where normally only 

non-conductive atmospheres are present). Occasionally, however, a 

temporary conductivity caused by condensation must be expected, in 

accordance with IEC 664.

Nitrogen Consumption

 Gas flow RapidVap N2 with 8 active nozzles:

0.55 SCFM @ 12 psi

0.41 SCFM @ 6 psi

 Gas flow RapidVap N2/48with 48 active nozzles:

3.5 SCFM @ 20 psi

2.5 SCFM @ 10 psi

N
Appendix C: RapidVap Specifications

56 Product Service 1-800-522-7658

Original instructions

Wiring Diagram (115V Models)
Appendix C: RapidVap Specifications

Product Service 1-800-522-7658 57

Original instructions

Wiring Diagram (230V Models)
Appendix C: RapidVap Specifications

58 Product Service 1-800-522-7658

Original instructions

Evaporation Rates

RapidVap Vacuum Models

The following tables show the approximate time to evaporate various solvents in 

75mm and 16mm sample tubes when the sample block is fully loaded. Other 

sample blocks are available for different size tubes. If they are used or if a

different number of samples is run at one time, the evaporation times can be 

estimated from these charts or determined experimentally.

Evaporation Time – 75 mm dia. Sample Tube

(Time in Minutes)

Solvent:

Methylene 

Chloride Toluene Acetonitrile Water

Block Preheat &

Block Set Point 

Temperature:

50°C 80°C 75°C 80°C

Vacuum: 250 mbar 133 mbar 167 mbar 133 mbar

Starting Volume

300ml 62 90 102 402

250 56 72 84 345

200 49 66 71 289

150 42 57 60 239

100 36 33 49 189

50 22 40 37 95

Number of samples: 8

Vortex speed: 28%

Vacuum pump: Labconco model – 79249-00

Rated free air flow – 88 L/min

Max. attainable vacuum – 31 mbar

V
Appendix C: RapidVap Specifications

Product Service 1-800-522-7658 59

Original instructions

Evaporation Time – 16 mm dia. Sample Tube

(Time in Minutes)

Solvent:

Methylene 

Chloride Toluene Acetonitrile Water

Block Preheat &

Block Set Point 

Temperature:

50°C 80°C 75°C 80°C

Vacuum: 200 mbar 200 mbar 330 mbar 133 mbar

Starting Volume

10 ml 18 25 25 119

8 14 20 22 101

6 10 14 17 72

4 8 12 13 50

2 4 6 7 26

Number of samples: 69

Vortex speed: 95%

Vacuum pump: Labconco model – 79249-00

Rated free air flow – 88 L/min

Max. attainable vacuum – 31 mbar

RapidVap N2 Models

The following tables indicate the approximate time required to evaporate various 

common solvents. Tables A and B show the average time required to evaporate 8 

samples from the selected beginning volume to a level where the solvent is at the 

top of the Cool-Zone stem. Tables C shows the average time to evaporate various 

solvents in different length Cool-Zone stems. It shows the average time for 

solvents to evaporate from the top of the stem to the indicated remaining volume 

when 8 vials are run simultaneously. The following example illustrates the use of 

the charts:

Assume that a starting volume of 300 ml methylene chloride is 

placed in a 600 ml sample vial with a 1.5 ml stem. The vial is 

covered with a cap. The desired endpoint volume is 0.5 ml. From 

Table A, the time to evaporate to the top of the stem is 59 minutes. 

From Table C, the time to evaporate from the top of the stem to 0.5 

ml is 17 minutes. Adding the two times together, the total time to 

evaporate 300 ml of methylene chloride to 0.5 ml in a sample tube 

with a 1.5 ml stem is approximately 76 minutes.

If fewer than eight samples are run at a time, the time to evaporate 

will become shorter.

V

N
Appendix C: RapidVap Specifications

60 Product Service 1-800-522-7658

Original instructions

Solvent:

Methylene 

Chloride

Ethyl

Acetate Hexanes Acetone Toluene Water

Block Preheat & 

Block Set Point 

Temperature: 40°C 75°C 70°C 55°C 100°C 95°C

Starting Volume

450 ml 91 82 54 90 109 623

400 80 65 52 75 80 531

350 69 56 35 64 69 437

300 59 48 29 54 60 379

250 51 40 22 45 50 323

200 43 33 19 38 41 270

150 36 26 16 31 32 221

100 28 19 11 23 23 173

50 18 12 7 14 13 106

Note 1: Even though the RapidVap N2 is capable of processing starting volumes 

as high as 450 ml using the 600 ml sample vial, its optimum volume is 300 ml. 

Above 300 ml, the vortex speed must be reduced and the nitrogen pressure must be 

decreased to prevent the sample from splashing out. This data for starting volumes 

over 300 ml was generated by starting the evaporation at reduced levels of nitrogen 

pressure and vortex speed. As the solvent evaporated, the nitrogen pressure and 

vortex speed were increased.

Table A

Evaporation Time in Upper Portion of Sample Vial

(600 ml Sample Tubes) (Time in Minutes)

N

Number of samples: 8

Nitrogen pressure: 10 psi at volumes 0 thru 300 ml

(see Note 1) 5 psi at volumes above 300 thru 350 ml

4 psi at volumes above 350 thru 400 ml

2 psi at volumes above 400 thru 450 ml

Vortex speed: 70% at volumes 0 thru 300 ml

(see Note 1) 36% at volumes above 300 thru 450 ml

Sample tubes covered with caps
Appendix C: RapidVap Specifications

Product Service 1-800-522-7658 61

Original instructions

Solvent:

Methylene 

Chloride

Ethyl

Acetate Hexanes Acetone Toluene Water

Block Preheat & 

Block Set Point 

Temperature: 40°C 75°C 70°C 55°C 100°C 95°C

Starting Volume

450 ml 58 56 33 68 75 420

400 53 48 29 61 63 352

350 48 40 24 54 52 321

300 41 35 21 47 45 266

250 35 31 19 43 40 230

200 30 26 16 38 35 193

150 25 22 14 34 28 153

100 19 17 11 29 22 120

50 10 9 7 16 15 68

Table B

Evaporation Time in Upper Portion of Sample Vial

(600 ml Sample Tubes) (Time in Minutes)

N

Number of samples: 8

Nitrogen pressure: 10 psi at volumes 0 thru 300 ml

(see Note 1) 5 psi at volumes above 300 thru 350 ml

4 psi at volumes above 350 thru 400 ml

2 psi at volumes above 400 thru 450 ml

Vortex speed: 70% at volumes 0 thru 300 ml

(see Note 1) 36% at volumes above 300 thru 450 ml

Sample tubes: Not covered with caps
Appendix C: RapidVap Specifications

62 Product Service 1-800-522-7658

Original instructions

Solvent:

Methylene 

Chloride

Ethyl

Acetate Hexanes Acetone Toluene Water

Block 

Preheat & 

Block Set 

Point Temp: 40°C 75°C 70°C 55°C 100°C 95°C

Glassware

Ending 

Volume

0.5 ml Stem 0.5

Dry

4

10

4

9

3

7

4

9

5

10

42

78

1.5 ml Stem 1.5

1.0

0.5

Dry

4

9

17

31

4

7

13

24

2

5

8

16

3

7

12

22

5

9

15

26

23

43

75

120

2.0 ml Stem 2.0

1.0

Dry

3

17

64

3

11

34

2

8

26

3

15

47

4

14

50

28

80

201

3.0 ml Stem 3.0

2.0

1.0

Dry

4

20

57

128

4

12

34

81

3

10

25

52

3

16

50

108

5

17

40

89

34

76

170

339

Table C

Evaporation Rate in Cool-Zone Stem

(600 ml Sample Tubes) (Time in Minutes)

Number of samples: 8

Vortex speed: 70%

Nitrogen pressure: 10 psi

Sample tubes: Covered or not covered with caps

Glassware Used:

0.5 ml (PN 79259-00) .77 in (1.9 cm) Long Stem

1.5 ml (PN 79139-00) 1.37 in (3.5 cm) Long Stem

2.0 ml (PN 79137-00) 1.62 in (4.1 cm) Long Stem

3.0 ml (PN 79135-00) 2.25 in (5.7 cm) Long Stem

N
Appendix C: RapidVap Specifications

Product Service 1-800-522-7658 63

Original instructions

RapidVap N2/48 Models

The following tables show the approximate time to evaporate various solvents in 

12mm and 20mm sample tubes when the sample block is fully loaded. Other 

sample blocks are available for different size tubes. If they are used or if a 

different number of samples is run at one time, the evaporation times can be 

estimated from these charts or determined experimentally. Evaporation rates may 

vary from tube to tube.

Solvent:

Methylene 

Chloride

Toluene Acetonitrile Methanol Hexane/

Ethyl Acetate

75:25

Hexane/

Ethyl Acetate

50:50

Block Preheat 

& Block Set 

Point Temp: 40°C 80°C 75°C 40°C 40°C 40°C

Starting Volume

2 ml 6 8 8 18 5 5

Evaporation Time RapidVap N2/48 Models

(12 mm Sample Tubes) (Time in Minutes)

Number of samples: 48

Vortex speed: 100%

Nitrogen pressure: 8 psi

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Appendix C: RapidVap Specifications

64 Product Service 1-800-522-7658

Original instructions

Solvent:

Methylene 

Chloride

Toluene Acetonitrile Methanol Hexane/

Ethyl Acetate

75:25

Hexane/

Ethyl Acetate

50:50

Block Preheat & 

Block Set Point 

Temp: 50°C 80°C 75°C 40°C 40°C 40°C

Starting Volume

10 ml 17 23 24 49 18 20

8 14 21 21

6 11 18 18

4 9 15 14

2 5 9 8

Evaporation Time RapidVap N2/48 Models

(20 ml Sample Tubes) (Time in Minutes)

Number of samples: 48

Vortex speed: 100%

Nitrogen pressure: 20 psi
Product Service 1-800-522-7658 65

Original instructions

APPENDIX D

RAPIDVAP ACCESSORIES

This following accessories are available for the RapidVap Vacuum model.

PART # DESCRIPTION

7491300 Block. 110-12 mm dia. tubes.

7485800 Block. 110-13 mm dia. tubes.

7491400 Block. 69-16 mm dia. tubes.

7496300 Block. 69-15 ml centrifuge tubes.

7496400 Block. 26-28 mm scintillation tubes.

7494500 Block. 8-600 ml tubes. Order tubes from Labconco.

7486400 Block. 8-170 ml tubes. Order tubes from Labconco.

Block. Special orders (size and number of tubes). Contact Labconco.

7909200 Sample Tube – Flat Bottom. Borosilicate glass. 600 ml capacity. 

Package of one (1).

7913408 Sample Tube – Flat Bottom. Borosilicate glass. 600 ml capacity. 

Package of eight (8).

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Appendix D: RapidVap Accessories

66 Product Service 1-800-522-7658

Original instructions

PART # DESCRIPTION

7927000 Sample Tube – Flat Bottom. Borosilicate glass. 170 ml capacity. 

Package of one (1).

7927108 Sample Tube – Flat Bottom. Borosilicate glass. 170 ml capacity. 

Package of eight (8).

7393000 Vacuum Pump. Diaphragm pump - corrosion resistant. 115V, 60 Hz, 

4.0 amps, single phase. 63 liters per minute, 1.5 mbar max vacuum.

7393001 Vacuum Pump. Diaphragm pump - corrosion resistant. 230V, 50/60

Hz, 3.0 amps, single phase. 63 liters per minute, 1.5 mbar max 

vacuum.

7587000 Vacuum Pump. Scroll pump. 115 VAC, 50/60 Hz, 10 amps, single 

phase. 189/195 liters per minute, 7 x 10-3 mbar max vacuum. Requires 

1⁄2 fitting 1472701.

7587002 Vacuum Pump. Scroll pump. 230 VAC, 50/60 Hz, 6 amps, single 

phase. 189/195 liters per minute, 7 x 10-3 mbar max vacuum. Requires 

1⁄2 fitting 1472701.

7587300 Silencer. For scroll pumps 7587000 and 7587002.

1472700 Fitting. For scroll pumps 7587000 and 7587002. For 1⁄2 I.D. hose.

7815300 Secondary Trap Canister. Includes stand and fittings. Requires an 

insert suitable for the application.

7814800 Acid Trap Insert. Installs inside secondary trap canister. Contains 

acid neutralizing desiccant.
Appendix D: RapidVap Accessories

Product Service 1-800-522-7658 67

Original instructions

PART # DESCRIPTION

7814900 Moisture Trap Insert. Installs inside secondary trap canister. 

Contains desiccant.

7815000 Radioisotope Trap Insert. Installs inside secondary trap canister. 

Contains activated charcoal.

7815200 Solvent Trap Insert. Installs inside secondary trap canister. Contains 

molecular sieve.

7538000 Secondary Vacuum Trap. 9 3⁄4" h x 7 7/8" diameter with 3⁄4" vacuum 

connections. Volume of inner pot holds 2.85 liters of dry ice and 

alcohol. Ice trapping capacity is over 900 ml. Shipping weight 9 lbs.

7538200 Secondary Vacuum Trap. 9 3⁄4" h x 7 7/8" diameter with 1/2" vacuum 

connections. Volume of inner pot holds 2.85 liters of dry ice and 

alcohol. Ice trapping capacity is over 900 ml. Shipping weight 9 lbs.

7538400 Secondary Vacuum Trap. 7 7/8" h x 6 5/8" diameter with 1/2" 

vacuum connections. Volume of inner pot holds 1.8 liters of dry ice and 

alcohol. Ice trapping capacity is 200 ml. Shipping weight 5 lbs.

7486500 Lid Heater. Includes glass lid with heater attached.

7873400 Liquid Trap. Capable of trapping 2,550 ml.

7970500 Liquid Trap. Capable of trapping 240 ml.

7348000 Trapping Valve. Requires a user supplied trap.
Appendix D: RapidVap Accessories

68 Product Service 1-800-522-7658

Original instructions

The following accessories are available for the RapidVap N2.

PART # DESCRIPTION

7486400 Block. 8–170 ml tubes. Order tubes from Labconco.

7927000 Sample Tube – Flat Bottom. Borosilicate glass. 170 ml capacity. 

Package of one (1).

7927108 Sample Tube – Flat Bottom. Borosilicate glass. 170 ml capacity. 

Package of eight (8).

7926600 Sample Tube – End Point Stem 1.5 ml. Borosilicate glass. 170 ml 

capacity. Package of one (1).

7926908 Sample Tube – End Point Stem 1.5 ml. Borosilicate glass. 170 ml 

capacity. Package of eight (8).

7909200 Sample Tube – Flat Bottom. Borosilicate glass. 600 ml capacity. 

Package of one (1).

7913408 Sample Tube – Flat Bottom. Borosilicate glass. 600 ml capacity. 

Package of eight (8).

7925900 Sample Tube – End Point Volume 0.5 ml. Borosilicate glass. 600 

ml capacity. Package of one (1).

7926008 Sample Tube – End Point Volume 0.5 ml. Borosilicate glass. 600 

ml capacity. Package of eight (8).

7913900 Sample Tube – End Point Volume 1.5 ml. Borosilicate glass. 600 

ml capacity. Package of one (1).

7914008 Sample Tube – End Point Volume 1.5 ml. Borosilicate glass. 600 

ml capacity. Package of eight (8).

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Appendix D: RapidVap Accessories

Product Service 1-800-522-7658 69

Original instructions

PART # DESCRIPTION

7913700 Sample Tube – End Point Volume 2 ml. Borosilicate glass. 600 ml 

capacity. Package of one (1).

7913808 Sample Tube – End Point Volume 2 ml. Borosilicate glass. 600 ml 

capacity. Package of eight (8).

7913500 Sample Tube – End Point Volume 3 ml. Borosilicate glass. 600 ml 

capacity. Package of one (1).

7913608 Sample Tube – End Point Volume 3 ml. Borosilicate glass. 600 ml 

capacity. Package of eight (8).

7487600 Rack – For 600 ml Sample Tubes. Holds eight (8) tubes.

7486300 Rack – For 170 ml Sample Tubes. Holds eight (8) tubes.

7925408 Sample Tube Cap–PTFE – For 600 ml Sample Tubes. Package of 

eight (8).

7926808 Sample Tube Cap–PTFE – For 170 ml Sample Tubes. Package of 

eight (8).

7926508 Sample Tube Cap–Polyethylene – For 170 ml Sample Tubes.

Package of eight (8).

7925500 Sample Tube Cap–Polyethylene – For 600 ml Sample Tubes.

Package of one (1).
Appendix D: RapidVap Accessories

70 Product Service 1-800-522-7658

Original instructions

The following accessories are available for the RapidVap N2/48.

PART # DESCRIPTION

7482100 Block. 48 – 12 x 75 mm tubes.

7482200 Block. 48 – 13 x 100 mm tubes.

7482300 Block. 48 – 16 x 150 mm tubes.

7482400 Block. 48 – 20 x 150 mm tubes.

7494500 Block. 8 – 600 ml glass tubes.

7909200 Glass Tubes for Block 74945-00. 600 ml flat bottom. Pkg. of 1.

7913408 Glass Tubes for Block 74945-00. 600 ml flat bottom. Pkg. of 8.

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