EXHIBIT 10.3
                                                                    ------------
                                     FORM OF
                                     -------
                       FIRST AMENDMENT TO GRANT AGREEMENT
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                                       OF
                                       --
                                  CHATTEM, INC.
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          (APPLIES ONLY TO OPTIONEES OTHER THAN EXECUTIVE OFFICERS(1))


         THIS FIRST AMENDMENT TO GRANT AGREEMENT (this "Amendment") is made and
entered to be effective as of the 30th day of November, 2005 (the "Effective
Date"), by and between Chattem, Inc., a Tennessee corporation ("Chattem"), and
________________________ ("Optionee"), and amends the Grant Agreement (as
defined below). Capitalized terms used herein but not defined shall have the
meaning ascribed to such terms in the Chattem, Inc. Stock Incentive Plan - 2005
(the "Plan").

         WHEREAS, pursuant to the Plan, as adopted by the Board of Directors on
January 25, 2005 and approved by Chattem's shareholders at their annual meeting
on April 13, 2005, the Committee has granted certain Non-Qualified Stock Options
(the "Granted Options") to Optionee as set forth on Schedule A hereto, in
accordance with the provisions of the Grant Agreement dated _________, 2005, the
Terms and Conditions of Stock Option Grant attached thereto (collectively, the
"Grant Agreement") and the Plan;

         WHEREAS, the Grant Agreement outlines a four-year vesting schedule (the
"Vesting Schedule"), pursuant to which the Granted Options will become vested in
Optionee; and

         WHEREAS, the Committee has approved certain modifications to the Grant
Agreement as reflected in this Amendment, and Chattem and Optionee desire to
enter into this Amendment, upon the terms and conditions set forth herein.

         NOW, THEREFORE, in consideration of the premises and mutual covenants
and obligations set forth herein, and for other good and valuable consideration,
the receipt and legal sufficiency of which is hereby acknowledged, the parties
hereto agree to amend the Grant Agreement as follows:

         1.    Notwithstanding the Vesting Schedule set forth in the Grant
Agreement, the vesting of any and all unvested Granted Options is hereby
accelerated, and such Granted Options shall become fully vested as of the
Effective Date.

         2.    Except as specifically amended hereby, the Grant Agreement shall
remain in full force and effect as originally executed.
_______________

(1) This Amendment does not apply to any of the following Optionees: Zan Guerry,
Robert E. Bosworth, Andrea M. Crouch, Ron Galante, Richard W. Kornhauser,
Richard D. Moss, B. Derrill Pitts, Donald K. Riker, Charles M. Stafford,
Theodore K. Whifield, Jr., Blair Ramey, Dean Patten and Joe Czerwinski.
<PAGE>


         IN WITNESS WHEREOF, this First Amendment to Grant Agreement of Chattem,
Inc. is hereby executed to be effective as of the date first above written.



                                               CHATTEM:

                                               CHATTEM, INC.


                                               ______________________________

                                               By: __________________________





                                               OPTIONEE:


                                               ______________________________

                                               Printed Name:_________________














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