Exhibit 21

Medtronic, Inc. and subsidiaries

Company

Jurisdiction of IncorporationArterial Vascular Engineering Canada, Company

Nova ScotiaArterial Vascular Engineering Netherlands Holding B.V.

NetherlandsArterial Vascular Engineering UK Limited

United KingdomAVE Ireland Limited

IrelandAVECOR Cardiovascular Limited

England, WalesB.V. Medtronic FSC

NetherlandsCardiotron G.m.b.H.

GermanyCarmel Biosensors Ltd.

IsraelEuroprisme Medical S.A.

FranceFundacion Medtronic Aula Miguel Servet

SpainIGN AB

SwedenIGN GmbH

GermanyIndia Medtronic Private Limited

IndiaKyphon Americas, Inc.

DelawareKyphon Australia Pty Ltd.

AustraliaKyphon Cayman Ltd.

Cayman IslandsKyphon Deutschland GmbH

GermanyKyphon Europe BVBA

BelgiumKyphon France SARL

FranceKyphon GmbH (Austria)

AustriaKyphon Iberica, S.L.

SpainKyphon Ireland Ltd.

IrelandKyphon Ireland Research Holding

IrelandKyphon Italia S.R.L.

ItalyKyphon Nippon K.K.

JapanKyphon South Africa (Proprietary) Ltd.

South AfricaKyphon Switzerland GmbH

SwitzerlandKyphon Sàrl

SwitzerlandKyphon UK Limited

United KingdomMG Biotherapeutics LLC

DelawareMRM Merger Corporation

DelawareMagnolia Medical, LLC

DelawareMedical Education Y.K.

JapanMedtronic (Africa) (Proprietary) Limited

South AfricaMedtronic (Schweiz) A.G. (Medtronic (Suisse) S.A.)

SwitzerlandMedtronic (Shanghai) Ltd.

ChinaMedtronic (Thailand) Limited

ThailandMedtronic A/S

DenmarkMedtronic Aktiebolag

SwedenMedtronic Angiolink, Inc.

DelawareMedtronic Asia, Ltd.

MinnesotaMedtronic Australasia E.S.P. Company Pty. Limited

AustraliaMedtronic Australasia Pty. Limited

New South WalesMedtronic B.V.

NetherlandsMedtronic Bakken Research Center B.V.

NetherlandsMedtronic Belgium S.A./N.V.

BelgiumMedtronic Bio-Medicus, Inc.

MinnesotaMedtronic China, Ltd.

MinnesotaMedtronic Comercial Ltda.

Brazil




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Company

Jurisdiction of IncorporationMedtronic Czechia s.r.o.

Czech RepublicMedtronic Danmark A/S

DenmarkMedtronic Endonetics, Inc.

CaliforniaMedtronic Europe BVBA/SPRL

BelgiumMedtronic Europe Sàrl

SwitzerlandMedtronic Fabrication SAS

FranceMedtronic Finland Oy

FinlandMedtronic France S.A.S.

FranceMedtronic Functional Diagnostics Zinetics, Inc.

UtahMedtronic Functional Diagnostics, Inc.

New JerseyMedtronic G.m.b.H.

GermanyMedtronic Hellas Medical Device Commercial S.A.

GreeceMedtronic Holding Switzerland G.m.b.H.

SwitzerlandMedtronic Hungaria Kereskedelmi Kft

HungaryMedtronic Ibérica S.A.

SpainMedtronic InStent (Israel) Ltd.

IsraelMedtronic International Technology, Inc.

MinnesotaMedtronic International Trading Sàrl

SwitzerlandMedtronic International Trading, Inc.

MinnesotaMedtronic International, Ltd.

DelawareMedtronic Interventional Vascular, Inc.

MassachusettsMedtronic Ireland Holdings Company

IrelandMedtronic Ireland Limited

IrelandMedtronic Ireland Manufacturing Limited

IrelandMedtronic Italia S.p.A.

ItalyMedtronic Japan Co., Ltd.

JapanMedtronic Korea Co. Ltd.

KoreaMedtronic LLC

RussiaMedtronic Latin America, Inc.

MinnesotaMedtronic Lifelink MD, Inc.

DelawareMedtronic Limited

United KingdomMedtronic Medical Appliance Technology and Service (Shanghai) Ltd.

ChinaMedtronic Medical Technology Ticaret Limited Sirketi

TurkeyMedtronic Mediterranean SAL

Beirut, LebanonMedtronic Mexico S. de R.L. de C.V. (Tijuana)

MexicoMedtronic Micro Motion Sciences, Inc.

DelawareMedtronic MiniMed, Inc.

DelawareMedtronic Navigation Israel Ltd.

IsraelMedtronic Navigation, Inc.

DelawareMedtronic Norge AS

NorwayMedtronic Oesterreich G.m.b.H.

AustriaMedtronic PS Medical, Inc.

CaliforniaMedtronic Pacific Trading, Inc.

MinnesotaMedtronic Physio-Control Limited

United KingdomMedtronic Poland Sp. z o.o.

PolandMedtronic Portugal - Comércio e Distribuiçao de Aparelhos Médicos Lda

PortugalMedtronic Puerto Rico Operations Co.

Cayman IslandsMedtronic S. de R.L. de C.V. (Mexico City)

MexicoMedtronic S.A.I.C.

ArgentinaMedtronic Servicios S. de R.L. de C.V.

Mexico




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Company

Jurisdiction of IncorporationMedtronic Sofamor Danek (NZ) Limited

New ZealandMedtronic Sofamor Danek (UK) Ltd.

England, WalesMedtronic Sofamor Danek Australia Pty. Ltd.

AustraliaMedtronic Sofamor Danek Co., Ltd.

JapanMedtronic Sofamor Danek Deggendorf GmbH

GermanyMedtronic Sofamor Danek South Africa (Proprietary) Limited

South AfricaMedtronic Sofamor Danek USA, Inc.

TennesseeMedtronic Sofamor Danek, Inc.

IndianaMedtronic Spine International Holding Company

Cayman IslandsMedtronic Spine LLC

DelawareMedtronic Synectics Aktiebolag

SwedenMedtronic Trading NL BV

NetherlandsMedtronic Transneuronix, Inc.

DelawareMedtronic Treasury International, Inc.

MinnesotaMedtronic Treasury Management, Inc.

MinnesotaMedtronic USA, Inc.

MinnesotaMedtronic Vascular Connaught

IrelandMedtronic Vascular Galway Limited

IrelandMedtronic Vascular, Inc.

DelawareMedtronic Vertelink, Inc.

CaliforniaMedtronic VidaMed, Inc.

DelawareMedtronic World Trade Corporation

MinnesotaMedtronic Xomed Instrumentation SAS

FranceMedtronic Xomed U.K. Limited

United KingdomMedtronic Xomed, Inc.

DelawareMedtronic do Brasil Ltda.

BrazilMedtronic of Canada Ltd.

CanadaMedtronic, Inc.

MinnesotaMedtronic-Mediland (Taiwan) Ltd.

TaiwanMiniMed Distribution Corp.

DelawareMiniMed Pty Ltd.

AustraliaNDI Medical, Inc.

OhioPhysio-Control International, Inc.

WashingtonPhysio-Control Manufacturing, Inc.

WashingtonPhysio-Control, Inc.

WashingtonRestoragen, Inc.

DelawareS.F.M.T. Europe B.V.

NetherlandsSanatis GmbH

SwitzerlandSetagon, Inc.

DelawareSociete De Fabrication de Material Orthopedique En Abrege Sofamor

FranceSpinalGraft Technologies, LLC

TennesseeSt. Francis Medical Technologies UK Limited

United KingdomSynectics Medical - Equipamento Electronico de Medicina, Limitada

PortugalSynectics Medical Limited

United KingdomTransneuronix International GmbH

GermanyVidaMed International Limited

United KingdomVitatron A.G.

SwitzerlandVitatron BV

NetherlandsVitatron Belgium S.A./N.V.

BelgiumVitatron Czechia s.r.o.

Czech RepublicVitatron Denmark A/S

Denmark




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Company

Jurisdiction of IncorporationVitatron Finland Oy

FinlandVitatron GmbH

AustriaVitatron GmbH

GermanyVitatron Holding B.V.

NetherlandsVitatron Japan Co., Ltd.

JapanVitatron Medical España, S.A.

SpainVitatron Nederland B.V.

NetherlandsVitatron Portugal - Comércio e Distribuição de Dispositivos Médicos, Lda

PortugalVitatron Sweden Aktiebolag

SwedenVitatron U.K. Limited

United KingdomWarsaw Orthopedic, Inc.

Indiana


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