alea-institute/kl3m-data-sample-004-shuffled huggingface dataset:
Bethesda, 

We have a problem

CHRISTINE COLVIS, PH.D.
The Problem

Pre-clinical research findings 

are not reproducible

• NIH - $30B/year

• Big pharma $4-5B per drug

• Small pharma $350M* per drug

Forbes Pharma & Healthcare 8/11/13
The contributors

• Publish or perish culture

 Number of publications is incentivised

• Poorly described materials and methods

 Journals that restrict the length

• Poor research design – inadequate training

 Studies are often unblinded

 Statistically underpowered

• Negative results are not published

 No venue to report inability to reproduce a published finding

• Poor quality of materials

 Contamination or mislabelling
Principles and Guidelines for Reporting 

Preclinical Research

• Rigorous statistical analysis

• Transparency in Reporting

 Standards

 Replicates

 Statistics

 Randomization

 Blinding

 Sample size

 Inclusion/Exclusion cireteria

• Data and material sharing

• Consideration of refutations
Consider establishing best practice 

guidelines for:

• Image based data (image screening for manipulation, Western blots, for example)

• Description of biological material with enough 

information to uniquely identify the reagents (for 

example unique accession number in repository), in 

particular for:

 antibodies: also report source, characteristics, dilutions and 

how they were validated

 cell lines: also report source, authentication and mycoplasma 

contamination status

 animals: also report source, species, strain, sex, age, 

husbandry, inbred and strain characteristics of transgenic 

animals
Training

This RFA will support creative educational activities with a 

primary focus on developing courses for skills development 

to enhance data reproducibility.
Encouraging public discourse

Quality of Materials
Mitigation of the contributors

• Publish or perish culture

 NIH revamped the biosketch for applications

• Poorly described materials and methods

 NPG eliminated limits

• Poor research design – inadequate training

 NIH published guidelines adopted by 80+ journals

 NIH is offering support for additional training

• Negative results are not published

 Articles are now better linked 

 PubMed Commons

• Poor quality of materials

 International Cell Line Authentication Committee
<TABLE> <S> <C>

<ARTICLE>           9
<MULTIPLIER>        1,000

<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          DEC-31-1997
<PERIOD-START>                             JAN-31-1997
<PERIOD-END>                               DEC-31-1997
<CASH>                                       1,171,727
<INT-BEARING-DEPOSITS>                         240,578
<FED-FUNDS-SOLD>                               292,384
<TRADING-ASSETS>                                70,486
<INVESTMENTS-HELD-FOR-SALE>                  7,225,638
<INVESTMENTS-CARRYING>                         249,434
<INVESTMENTS-MARKET>                           252,135
<LOANS>                                     19,199,917
<ALLOWANCE>                                    254,983
<TOTAL-ASSETS>                              29,955,411
<DEPOSITS>                                  22,079,927
<SHORT-TERM>                                 3,465,822
<LIABILITIES-OTHER>                            355,340
<LONG-TERM>                                  1,469,153
<PREFERRED-MANDATORY>                                0
<PREFERRED>                                          0
<COMMON>                                         1,307
<OTHER-SE>                                   2,408,862
<TOTAL-LIABILITIES-AND-EQUITY>              29,955,411
<INTEREST-LOAN>                              1,464,844
<INTEREST-INVEST>                              388,879
<INTEREST-OTHER>                                24,471
<INTEREST-TOTAL>                             1,878,194
<INTEREST-DEPOSIT>                             741,058
<INTEREST-EXPENSE>                             957,690
<INTEREST-INCOME-NET>                          920,504
<LOAN-LOSSES>                                   79,309
<SECURITIES-GAINS>                               6,985
<EXPENSE-OTHER>                                894,780
<INCOME-PRETAX>                                325,099
<INCOME-PRE-EXTRAORDINARY>                     204,593
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   204,593
<EPS-PRIMARY>                                     1.68<F1>
<EPS-DILUTED>                                     1.65<F1>
<YIELD-ACTUAL>                                    3.93
<LOANS-NON>                                     97,914
<LOANS-PAST>                                    20,295
<LOANS-TROUBLED>                                 4,278
<LOANS-PROBLEM>                                 60,640
<ALLOWANCE-OPEN>                               230,372
<CHARGE-OFFS>                                  101,308
<RECOVERIES>                                    26,378
<ALLOWANCE-CLOSE>                              254,983
<ALLOWANCE-DOMESTIC>                           254,983
<ALLOWANCE-FOREIGN>                                  0
<ALLOWANCE-UNALLOCATED>                         87,151
<FN>
<F1> Effective October 1, 1997, the Corporation effected a three-for-two
stock split of its common stock. Prior financial data schedules filed by the
Corporation have not been restated to give effect to such stock split.


</TABLE>
IN THE SUPREME COURT OF THE STATE OF MONTANA

No. DA 24-0024 

STATE OF MONTANA,

Plaintiff and Appellee,

v.

SHANE WAYNE STANLEY,

Defendant and Appellant.

ORDER

Upon consideration of Appellant’s motion for extension of time, 

and good cause appearing,

IT IS HEREBY ORDERED that Appellant is granted an extension 

of time to and including October 3, 2024, within which to prepare, file, 

and serve Appellant’s opening brief on appeal.

Electronically signed by:

Mike McGrath

Chief Justice, Montana Supreme Court

August 27 2024

08/27/2024

Case Number: DA 24-0024
**EXHIBIT 23****CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM**We consent to theincorporation by reference in the Registration Statement Number 333-73306 onForm S-8 dated November 14, 2001, the Registration Statement Number 333-100841on Form S-8 dated October 30, 2002, the Registration Statement Number 333-129160on Form S-8 dated October 20, 2005 and the Registration Statement Number333-141620 on Form S-8 dated March 28, 2007 of our reports with respect to theconsolidated financial statements and schedule of Mentor Corporation, MentorCorporation management's assessment of the effectiveness of internal controlover financial reporting, and the effectiveness of internal control overfinancial reporting of Mentor Corporation, included in this Annual Report (Form10-K) for the year ended March 31, 2007.
 /s/ERNST & YOUNG LLPLos Angeles, California
Exhibit 31
                                  ----------



                                 CERTIFICATION
                                 -------------


     I, Steve Bailey, certify that:

     1. I have reviewed this annual report on Form 10-K, and all reports on
     Form 8-K containing distribution and servicing reports filed in respect
     of periods included in the year covered by this annual report, of CWMBS,
     Inc., Mortgage Pass-Through Trust 2004-HYB3;

     2. Based on my knowledge, the information in these reports, taken as a
     whole, does not contain any untrue statement of a material fact or omit
     to state a material fact necessary to make the statements made, in light
     of the circumstances under which such statements were made, not
     misleading as of the last day of the period covered by this annual
     report;

     3. Based on my knowledge, the distribution or servicing information
     required to be provided to the trustee by the master servicer under the
     pooling and servicing, or similar, agreement, for inclusion in these
     reports is included in these reports;

     4. I am responsible for reviewing the activities performed by the master
     servicer under the pooling and servicing, or similar, agreement and based
     upon my knowledge and the annual compliance review required under that
     agreement, and except as disclosed in the reports, the master servicer
     has fulfilled its obligations under that agreement; and

     5. The reports disclose all significant deficiencies relating to the
     master servicer's compliance with the minimum servicing standards based
     upon the report provided by an independent public accountant, after
     conducting a review in compliance with the Uniform Single Attestation
     Program for Mortgage Bankers or similar procedure, as set forth in the
     pooling and servicing, or similar, agreement, that is included in these
     reports.

     In giving the certifications above, I have reasonably relied on
     information provided to me by the following unaffiliated parties: The
     Bank of New York, as Trustee, ABN AMRO Mortgage Group, Inc. and
     Washington Mutual Bank, FA.


     Date: March 28, 2005


                                       /s/ Steve Bailey
                                       ----------------
                                       Steve Bailey
                                       Senior Managing Director
Agreed terms document under the joint venture shareholders' agreement dated [ ]
October 2005 among  Baltic  Petroleum  (E&P)  Limited,  Siberian  Energy  Group
Inc. and Zauralneftegaz Limited



                                 Waiver Letter


To:

Siberian Energy Group Inc.
275 Madison Avenue
6th Floor
New York
NY 10016
United States

Zauralneftegaz Limited
c/o Gilchrist Solicitors
18b Charles Street
London W1J 5DU
United Kingdom

Date: October [ ], 2005

Dear Sirs

SIBERIAN ENERGY GROUP INC.

I am writing this letter in connection with the proposed joint venture agreement
between Baltic Petroleum  (E&P)  Limited  ("BP"),  Siberian  Energy  Group  Inc.
("SEG") and Zauralneftegaz Limited  ("ZNG LTD") dated 14 October, 2005  relating
to OOO  Zauralneftegaz  ("ZNG").  I  acknowledge  that  delivery  of this waiver
letter is a condition precedent to completion of such  agreement  and  that  the
terms hereof may only be varied or amended with the  consent  of  both  SEG  and
ZNG Ltd.

I hereby confirm that, other than those claims against SEG which  are listed  in
the Schedule hereto (the "CLAIMS") and which has been settled as of October  26,
2005 by acceptance of  SEG's shares, [             ] has no  actual,  contingent
or prospective claim outstanding of any nature against SEG, ZNG or any of  their
respective directors, officers and employees or any of  them  in  respect of any
cause, matter or thing whatever.  However, to the extent  that  any  such  claim
(other  than  the  Claims) exists or may exist, [             ] Inc. irrevocably
waives  such claim and releases SEG,  ZNG  and/or  their  respective  directors,
officers and employees, as the case may be, from any  liability  in  respect  of
such claim.

I hereby confirm that [          ] shall not seek to exercise any rights against
SEG in relation to the Claims until such  time  as  SEG  shall  have  sufficient
profits available to discharge the Claims.

EXECUTED by

/s/ [signature]


                                  The Schedule
        Description of Claim                                  Amount ($)
    ----------------------------                          ----------------

<PAGE>
No. 01-15-00210-CV

IN THE

FIRST COURT OF APPEALS

HOUSTON, TEXAS

FRANCISCO CALLEJA-AHEDO

Appellant

V.

COMPASS BANK

Appellee

On Appeal from the 55 th District Court

Harris County, Texas.

Trial Cause No. 2014-22168

AGREED MOTION FOR EXTENSION

OF TIME TO FILE APPELLANT’S REPLY BRIEF

TO THE HONORABLE JUDGES OF SAID COURT:

COMES NOW, Appellant Francisco Calleja-Ahedo and files this agreed motion for

extension of time to file his Appellant’s Reply Brief and would show:

Appellant’s Reply Brief is due on November 12, 2015. Mr. O’Connor is presently

restricted in his work and other activities and cannot complete the brief by November 12, 2015

due to ongoing health issues. See Doctor’s letter attached hereto. In addition, Appellant’s ACCEPTED

01-15-00210-CV

FIRST COURT OF APPEALS

HOUSTON, TEXAS

11/2/2015 11:04:12 AM

CHRISTOPHER PRINE

CLERKattorney has had to postpone trials and arbitrations, which are now reset for later in November

and require substantial time and effort. Appellant’s attorney is unable to complete Appellant’s

Brief under such circumstances, which requires dealing with numerous issues and record review.

WHERFORE, Appellant requests a thirty (30) day extension, until December 12, 2015, to

file Appellant’s Reply Brief.

Respectfully Submitted,

O’CONNOR, CRAIG, GOULD & EVANS

By: /s/ Michael C. O’Connor_____

Michael C. O’Connor

State Bar No. 15187000

2825 Wilcrest Dr., Suite 261

Houston, TX 77042

713-266-3311

713-953-7513 (fax)

ATTORNEYS FOR APPELLANT

CERTIFICATE OF CONFERENCE

The undersigned certifies that he has conferenced by e-mail with Pat Huttenbach,

attorney for Appellee, who has agreed to this Motion.

By: /s/ Michael C. O’Connor_____

Michael C. O’Connor

CERTIFICATE OF SERVICE

I hereby certify that a true and correct copy of the foregoing document has been

forwarded to all counsel of record by electronic service in accordance with Rule 21a on this 2 nd

day of November, 2015.

By: /s/ Michael C. O’Connor_____

Michael C. O’Connor
ITL Speaker Request for Colleges and Universities 

Please fill out the information below and send it to itl-speakers-bureau@nist.gov. 

Name and title of requester: 

Email:

Phone number: 

Educational Institution: 

Event: 

Preferred Date (actual date based on speaker's availability): 

Location/virtual: 

Topic area(s) of interest: 

Preferred speaker: 

Artificial Intelligence/Machine Learning

Computational Science/Applied Mathematics

Cybersecurity & Privacy

Digital Forensics

Human Factors, Usability

Information Retrieval

Intersection of Technology & Policy

Quantum Science

Statistics

Virtual Reality
Exhibit
(32.1)





CERTIFICATION
PURSUANT TO


18
U.S.C. SECTION 1350,


AS
ADOPTED PURSUANT TO


SECTION
906 OF THE SARBANES-OXLEY ACT OF 2002








The
undersigned officer hereby certifies, as to the Report on Form 10-K of Met-Pro
Corporation for the fiscal year ended January 31, 2008, that (i) the report
fully complies with the requirements of section 13(a) or 15(d) of the Securities
Exchange Act of 1934, and (ii) the information contained in the report
fairly presents, in all material respects, the financial condition and results
of operations of Met-Pro Corporation.






Date:
      April 11, 2008
            
            /s/    Raymond
      J. De HontRaymond
      J. De HontChairman,
      Chief Executive Officer and
President
IoT Cybersecurity Colloquium

Thursday, October 19th, 2017

The National Institute of Standards and Technology (NIST) Cybersecurity for IoT 

Program supports the development and application of standards, guidelines, and 

related tools to improve the cybersecurity of connected devices and the 

environments in which they are deployed. By collaborating with stakeholders 

across government, industry, international bodies, and academia, the program 

aims to cultivate trust and promote U.S. leadership in IoT.

Given stakeholder concerns and ongoing security incidents, there has been 

interest in NIST providing guidance for federal agencies on how to secure their IoT 

within their Federal Information Security Modernization Act (FISMA) 

responsibilities. While agencies are aware that IoT introduces security and privacy 

risks, there is confusion regarding how to address and mitigate these risks.

Having observed the broadened threat landscape and processed stakeholder 

feedback, the NIST Cybersecurity for IoT Program is interested in the prospect of 

providing guidance for federal agencies on common high-level security and 

privacy risks. The Program is hosting this colloquium to hear from the community 

about these concerns, better understand the threat landscape, gauge stakeholder 

interest in such guidance, and determine next steps.
IoT Cybersecurity Colloquium

Thursday, October 19th, 2017

Time Topic

8:00 AM Registrant Check-in

9:00 AM Opening Session

• James St. Pierre

Deputy Director, Information Technology Laboratory

• Kat Megas

Program Lead, NIST Cybersecurity for IoT Program

• Safety Overview

9:30 AM • Andrew Sullivan

Fellow, Oracle Dyn

Topic: DDoS

10:00 AM • Yasser Shoukry

Assistant Professor, University of Maryland

Topic: Sensor Security

10:30 AM • Joe Jarzombek

Global Manager, Software Supply Chain Solutions, Synopsys Software 

Integrity Group

Topic: Supply Chain

11:00 AM • Jeremy Grant

Managing Director of Technology Business Strategy, Venable

Topic: Identity for IoT

11:30 AM • Carlos Bosch

Head of Technology, GSMA North America

Topic: End-to-end Security

12:00 PM • Matthew Eggers

Executive Director, Cybersecurity Policy, U.S. Chamber of Commerce

Topic: IoT Cyber Policy

12:30 PM Lunch

1:30 PM • Gilad Rosner

Founder, Internet of Things Privacy Forum

Topic: Privacy for IoT

2:00 PM • Andrea Arias

Bureau of Consumer Protection, FTC

Topic: Consumer Landscape

2:30 PM • Arabella Hallawell

Senior Director, Advanced Threat, Arbor Networks

Topic: Devices Without Identity: IoT Risks for the Enterprise Network

3:00 Adjourn
Exhibit 31.1

                                                                         Certification of Principal Executive Officer

Pursuant to 18 U.S.C. 1350

(Section 302 of the Sarbanes-Oxley Act of 2002)
Exhibit 31.1

                                  CERTIFICATION

      I, John D. Ryan, certify that:

      1.    I have reviewed this Quarterly Report on Form 10-Q of Boundless
Corporation;

      2.    Based on my  knowledge,  this  report  does not  contain  any untrue
statement of a material fact or omit to state a material fact  necessary to make
the statements made, in light of the  circumstances  under which such statements
were made, not misleading with respect to the period covered by this report;

      3.    Based on my knowledge, the financial statements, and other financial
information included in this report, fairly present in all material respects the
financial condition, results of operations and cash flows of the registrant as
of, and for, the periods presented in this report;

      4.    I am responsible for establishing and maintaining disclosure
controls and procedures (as defined in Exchange Act Rules 13a-15(e) and
15d-15(e)) for the registrant and have:

            a)    designed such disclosure controls and procedures, or caused
      such disclosure controls and procedures to be designed under my
      supervision, to ensure that material information relating to the
      registrant, including its consolidated subsidiaries, is made known to me
      by others within those entities, particularly during the period in which
      this report is being prepared;

            b)    evaluated the effectiveness of the registrant's disclosure
      controls and procedures, and presented in this report my conclusions about
      the effectiveness of the disclosure controls and procedures, as of the end
      of the period covered by this report based on such evaluation; and

            c)    disclosed in this report any change in the registrant's
      internal control over financial reporting that occurred during the
      registrant's most recent fiscal quarter (the registrant's fourth fiscal
      quarter in the case of an annual report) that has materially affected, or
      is reasonably likely to materially affect, the registrant's internal
      control over financial reporting; and

      5.    I have disclosed, based on my most recent evaluation of internal
control over financial reporting, to the registrant's auditors and the audit
committee of the registrant's board of directors (or persons performing the
equivalent functions):

            a)    all significant deficiencies and material weaknesses in the
      design or operation of internal control over financial reporting which are
      reasonably likely to adversely affect the registrant's ability to record,
      process, summarize and report financial information; and

            b)    any fraud, whether or not material, that involves management
      or other employees who have a significant role in the registrant's
      internal control over financial reporting.

Date: March 6, 2006                  /s/ John D. Ryan
                                     ---------------------------------------
                                     John D. Ryan
                                     Acting Chief Executive Officer

                                    22 of 24
I 

108TH CONGRESS 

2D SESSION H. R. 4068

To amend the Help America Vote Act of 2002 to postpone the deadline 

by which a State is required to meet the election administration requirements of the Act until the total amount appropriated to the State 

for requirements payments under the Act is equal to or greater than 

the costs incurred by the State in meeting such requirements. 

IN THE HOUSE OF REPRESENTATIVES 

MARCH 30, 2004

Mr. GOODE introduced the following bill; which was referred to the Committee 

on House Administration 

A BILL

To amend the Help America Vote Act of 2002 to postpone 

the deadline by which a State is required to meet the 

election administration requirements of the Act until the 

total amount appropriated to the State for requirements 

payments under the Act is equal to or greater than 

the costs incurred by the State in meeting such requirements.

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled,

3 SECTION 1. SHORT TITLE. 

4 This Act may be cited as the ‘‘State and Local Gov5 ernment Election Administration Act of 2004’’. 
2

•HR 4068 IH 

1 SEC. 2. POSTPONEMENT OF DEADLINE FOR ELECTION AD2 MINISTRATION REQUIREMENTS. 

3 (a) IN GENERAL.—Subtitle A of title III of the Help 

4 America Vote Act of 2002 (42 U.S.C. 15481 et seq.) is 

5 amended by adding at the end the following new section: 

6 ‘‘SEC. 306. DELAY IN IMPLEMENTATION UNTIL FULL FUND7 ING OF COSTS INCURRED. 

8 ‘‘Notwithstanding any other provision of this title, no 

9 State (or jurisdiction within the State) shall be required 

10 to meet any of the requirements of this title until the later 

11 of—

12 ‘‘(1) the first day of the first calendar year 

13 which begins after the aggregate amount appro14 priated to the State for requirements payments for 

15 all fiscal years under section 257 is equal to or 

16 greater than the costs incurred by the State in meet17 ing the requirements of this title; or 

18 ‘‘(2) the applicable date otherwise provided 

19 under this title.’’. 

20 (b) CLERICAL AMENDMENT.—The table of contents 

21 for subtitle A of title III of such Act is amended by adding 

22 at the end the following:

‘‘Sec. 306. Delay in implementation until full funding of costs incurred.’’.
3

•HR 4068 IH 

1 (c) EFFECTIVE DATE.—The amendments made by 

2 this section shall take effect as if included in the enact3 ment of the Help America Vote Act of 2002.

Æ