Exhibit 31.1



CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER

PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002



I, Thomas G. Tachovsky, certify that:



1. I have reviewed this quarterly report on Form 10-QSB of Entropin, Inc.;



2. Based on my knowledge, this quarterly report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements
made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this quarterly report;



3. Based on my knowledge, the financial statements, and other financial information included in this quarterly report, fairly present in all material respects the
financial condition, results of operations and cash flows of the small business issuer as of, and for, the periods presented in this quarterly report;



4. The small business issuers other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in
Exchange Act Rules 13a-15(e) and 15d-15(e)) for the small business issuer and we have:



(a) designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the small business issuer,
is made known to us by others within this entity, particularly during the period in which this quarterly report is being prepared;



(b) evaluated the effectiveness of the small business issuers disclosure controls and procedures and presented in this report our conclusions about
the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this quarterly report based on such evaluation; and



(c) disclosed in this quarterly report any change in the small business issuers internal control over financial reporting that occurred during the
small business issuers most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the small business issuers internal control over financial reporting; and



5. The small business issuers other certifying officer and I have disclosed, based on
our most recent evaluation of internal control over financial reporting, to the small business issuers auditors and the audit committee of small business issuers board of directors (or persons performing the equivalent functions):



(a) all significant deficiencies and material weaknesses in
the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the small business issuers ability to record, process, summarize and report financial information; and



(b) any fraud, whether or not material, that involves management or other
employees who have a significant role in the small business issuers internal control over financial reporting.



Date: November 12, 2004



|                                                                
|----------------------------------------------------------------
|/s/ Thomas G. Tachovsky, Ph.D.                                  
|Thomas G. Tachovsky, Ph.D. President and Chief Executive
Officer