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Exhibit 21
 MERCK & CO., INC. SUBSIDIARIES
as of 12/31/05
  Country or StateName
    
    of IncorporationAMRAD Pharmaceuticals Pty. Ltd.
    
    AustraliaAton Pharma, Inc.
    
    DelawareBanyu Pharmaceutical Company, Ltd.
    
    JapanBlue Jay Investments C.V.
    
    NetherlandsBRC Ltd
    
    BermudaCharles E. Frosst (U.K.) Limited
    
    Great BritainChibret A/S
    
    DenmarkChibret Pharmazeutische GmbH
    
    GermanyChina-MSD HIV/AIDS Public Private Partnership, Inc.
    
    ChinaChippewa Holdings LLC
    
    DelawareCloverleaf International Holdings S.A.
    
    LuxembourgCM Delaware LLC
    
    DelawareComsort, Inc.
    
    DelawareCoophavet S.A.S.1
    
    FranceCoordinated Patient Care Scandinavia AS
    
    NorwayCrosswinds B.V.
    
    NetherlandsDieckmann Arzneimittel GmbH
    
    GermanyEuropean Insurance Risk Excess Limited
    
    IrelandFarmacox-Companhia Farmaceutica, Lda
    
    PortugalFarmasix-Produtos Farmaceuticos, Lda
    
    PortugalFinanciere MSD S.A.S.
    
    FranceFontelabor-Produtos Farmaceuticos, Lda.
    
    PortugalFregenal Holdings S.A.
    
    PanamaFrosst Iberica, S.A.
    
    SpainFrosst Laboratories, Inc.
    
    DelawareFrosst Portuguesa  Produtos Farmaceuticos, Lda.
    
    PortugalHangzhou MSD Pharmaceutical Company Limited1
    
    ChinaHawk and Falcon L.L.C.
    
    DelawareInfodoc AS1
    
    NorwayInternational Indemnity Ltd.
    
    BermudaIstituto Di Richerche Di Biologia Molecolare S.p.A.
    
    ItalyIstituto Gentili S.p.A./Inc.
    
    Italy/DelawareJohnson & Johnson  Merck Consumer Pharmaceuticals Company1
    
    New JerseyKBI Inc.
    
    DelawareKBI Sub Inc.
    
    DelawareKBI-E Inc.
    
    DelawareKBI-P Inc.
    
    DelawareKiinteisto Oy Viistotie 11
    
    FinlandLaboratoires Merck Sharp & Dohme-Chibret SNC
    
    FranceLaboratorios Abello, S.A.
    
    SpainLaboratorios Biopat, S.A.
    
    Spain




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Country or StateName
    
    of IncorporationLaboratorios Chibret, S.A.
    
    SpainLaboratorios Frosst, S.A.
    
    SpainLaboratorios Medichip S.L.
    
    SpainLaboratorios Neurogard, S.A.
    
    SpainLaboratorios Quimico-Farmaceuticos Chibret, Lda.
    
    PortugalMaple Leaf Holdings SRL
    
    BarbadosMCM Vaccine Co.1
    
    PennsylvaniaMedco de Mexico Managed Care S. de R.L. de C.V.
    
    MexicoMedco Holdings S. de R.L. de C.V.
    
    MexicoMedco Servicios de Mexico, S. de R.L. de C.V.
    
    MexicoMerck and Company, Incorporated
    
    DelawareMerck Borinquen Holdings, Inc.
    
    DelawareMerck Capital Resources, Inc.
    
    DelawareMerck Capital Ventures, LLC
    
    DelawareMerck Cardiovascular Health Company
    
    NevadaMerck Enterprises Canada, Ltd.
    
    CanadaMerck Finance Co., Inc.
    
    DelawareMerck Foreign Sales Corporation Ltd.
    
    BermudaMerck Frosst Canada Ltd.
    
    CanadaMerck Frosst Company
    
    CanadaMerck Frosst Finco LP
    
    CanadaMerck Hamilton, Inc.
    
    CaliforniaMerck Holdings II Corp.
    
    DelawareMerck Holdings, Inc.
    
    DelawareMerck Institute for Vaccinology
    
    DelawareMerck Investment Co., Inc.
    
    DelawareMerck Liability Management Company
    
    DelawareMerck LMC Cash Management (Bermuda) Ltd.
    
    BermudaMerck LMC Cash Management, Inc.
    
    DelawareMerck Oncology Holdings, Inc.
    
    DelawareMerck Resource Management, Inc.
    
    DelawareMerck Respiratory Health Company
    
    NevadaMerck SH Inc.
    
    DelawareMerck Sharp & Dohme (Argentina) Inc.
    
    DelawareMerck Sharp & Dohme (Asia) Limited
    
    Hong KongMerck Sharp & Dohme (Australia) Pty. Limited
    
    AustraliaMerck Sharp & Dohme (China) Limited
    
    Hong KongMerck Sharp & Dohme (Enterprises) B.V.
    
    NetherlandsMerck Sharp & Dohme (Europe) Inc.
    
    DelawareMerck Sharp & Dohme (Holdings) B.V.
    
    NetherlandsMerck Sharp & Dohme (Holdings) Limited
    
    Great BritainMerck Sharp & Dohme (I.A.) Corp.
    
    DelawareMerck Sharp & Dohme (International) Limited
    
    BermudaMerck Sharp & Dohme (Investments) B.V.
    
    NetherlandsMerck Sharp & Dohme (Ireland) Ltd.
    
    BermudaMerck Sharp & Dohme (Israel  1996) Company Ltd.
    
    IsraelMerck Sharp & Dohme (Italia) S.p.A.
    
    ItalyMerck Sharp & Dohme (Lebanon) S.A.L.
    
    LebanonMerck Sharp & Dohme (Middle East) Limited
    
    CyprusMerck Sharp & Dohme (New Zealand) Limited
    
    New Zealand




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Country or StateName
    
    of IncorporationMerck Sharp & Dohme (Panama) S.A.
    
    PanamaMerck Sharp & Dohme (Philippines) Inc.
    
    PhilippinesMerck Sharp & Dohme (Puerto Rico) Ltd.
    
    BermudaMerck Sharp & Dohme (Singapore) Ltd.
    
    BermudaMerck Sharp & Dohme (Sweden) A.B.
    
    SwedenMerck Sharp & Dohme Asia Pacific Services Pte Ltd.
    
    SingaporeMerck Sharp & Dohme B.V.
    
    NetherlandsMerck Sharp & Dohme Chibret A.G.
    
    SwitzerlandMerck Sharp & Dohme Comercializadora, S. de R.L. de C.V.
    
    MexicoMerck Sharp & Dohme d.o.o.
    
    CroatiaMerck Sharp & Dohme de Espana, S.A.
    
    SpainMerck Sharp & Dohme de Mexico S.A. de C.V.
    
    MexicoMerck Sharp & Dohme de Venezuela S.R.L.
    
    VenezuelaMerck Sharp & Dohme Farmaceutica Ltda.
    
    BrazilMerck Sharp & Dohme Finance Europe Limited
    
    Great BritainMerck Sharp & Dohme GmbH
    
    AustriaMerck Sharp & Dohme Holdings de Mexico, S.A. de C.V.
    
    MexicoMerck Sharp & Dohme IDEA, Inc.
    
    SwitzerlandMerck Sharp & Dohme Industria Quimica e Veterinaria Limitada
    
    BrazilMerck Sharp & Dohme inovativna zdravila d.o.o.
    
    SloveniaMerck Sharp & Dohme International Services B.V.
    
    NetherlandsMerck Sharp & Dohme Ireland (Human Health) Ltd
    
    IrelandMerck Sharp & Dohme Ísland hf
    
    IcelandMerck Sharp & Dohme L.L.C.
    
    Russian FederationMerck Sharp & Dohme Limited
    
    Great BritainMerck Sharp & Dohme Luxembourg (Holdings) S.a.r.l.
    
    LuxembourgMerck Sharp & Dohme Manufacturing
    
    IrelandMerck Sharp & Dohme O.U.
    
    EstoniaMerck Sharp & Dohme of Pakistan Limited
    
    PakistanMerck Sharp & Dohme Peru SRL
    
    PeruMerck Sharp & Dohme Quimica de Puerto Rico, Inc.
    
    DelawareMerck Sharp & Dohme Research Ltd.
    
    BermudaMerck Sharp & Dohme S. de R.L. de C.V.
    
    MexicoMerck Sharp & Dohme S.A.
    
    MoroccoMerck Sharp & Dohme SAS
    
    FranceMerck Sharp & Dohme SIA
    
    LatviaMerck Sharp & Dohme Tunisie Sarl
    
    TunisiaMerck Sharp & Dohme, Limitada
    
    PortugalMerck Sharp Dohme Ilaclari Limited Sirketi
    
    TurkeyMerck Technology (U.S.) Company, Inc.
    
    NevadaMerck Ventures, Inc.
    
    DelawareMerial (IA) LLP1
    
    Puerto RicoMerial (Thailand) Ltd1
    
    ThailandMerial Animal Health Co. Ltd.1
    
    ChinaMerial Animal Health Ltd1
    
    Great BritainMerial Argentina SA1
    
    ArgentinaMerial Asia PTE, Ltd.1
    
    SingaporeMerial Australia PTY LTD1
    
    AustraliaMerial B.V.1
    
    NetherlandsMerial Belgium 1
    
    Belgium




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Country or StateName
    
    of IncorporationMerial Colombia S.A.1
    
    ColombiaMerial Distribution SAS1
    
    FranceMerial GmbH1
    
    GermanyMerial Hong Kong Limited1
    
    Hong KongMerial Inc.1
    
    DelawareMerial International Trading (Shanghai) Co., Ltd.1
    
    ChinaMerial Italia SpA1
    
    ItalyMerial Japan, Limited1
    
    JapanMerial Korea Ltd1
    
    KoreaMerial Laboratorios SA1
    
    SpainMerial Limited/LLC1
    
    Great Britain/DelawareMerial Nanjing Animal Health Co. Ltd.1
    
    ChinaMerial New Zealand Limited1
    
    New ZealandMerial Norden A/S1
    
    DenmarkMerial Philippines, Inc.1
    
    PhilippinesMerial Portuguesa  Saude Animal LDA1
    
    PortugalMerial SA1
    
    UruguayMerial SAS 1
    
    FranceMerial Saude Animal LTDA1
    
    BrazilMerial Taiwan Co., Ltd.1
    
    TaiwanMerial Venezuela , C.A. 1
    
    VenezuelaML Holdings (Canada) Inc.
    
    CanadaMSD (Nippon Holdings) BV
    
    NetherlandsMSD (Norge) A/S
    
    NorwayMSD (Proprietary) Limited
    
    South AfricaMSD (Thailand) Ltd.
    
    ThailandMSD Australia Pty Ltd
    
    AustraliaMSD Australia Superannuation Pty Ltd.
    
    AustraliaMSD Brazil (Investments) B.V.
    
    NetherlandsMSD Chibropharm GmbH
    
    GermanyMSD Finance B.V.
    
    NetherlandsMSD Finance Mexico, LLC
    
    DelawareMSD International Holdings, Inc.
    
    DelawareMSD Ireland (Holdings) S.A.
    
    LuxembourgMSD Ireland (Investments) Ltd.
    
    BermudaMSD Korea Ltd.
    
    KoreaMSD Lakemedel (Scandinavia) Aktiebolog
    
    SwedenMSD Latin America Services Ltd.
    
    BermudaMSD Latin America Services S. de R.L. de C.V.
    
    MexicoMSD Limited
    
    Great BritainMSD Magyarország Kft
    
    HungaryMSD Mexico (Investments) B.V.
    
    NetherlandsMSD Overseas Manufacturing Co.
    
    BermudaMSD Overseas Manufacturing Co. (Ireland)
    
    IrelandMSD Pharmaceuticals Private Limited
    
    IndiaMSD Polska Sp.z.o.o.
    
    PolandMSD Sharp & Dohme GmbH
    
    GermanyMSD Somerset Ltd.
    
    BermudaMSD Stamford Singapore Pte Ltd
    
    SingaporeMSD Technology Singapore Pte. Ltd.
    
    Singapore




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Country or StateName
    
    of IncorporationMSD Technology, L.P.
    
    DelawareMSD Unterstutzungskasse GmbH
    
    GermanyMSD Ventures Singapore Pte. Ltd.
    
    SingaporeMSD Warwick (Manufacturing) Ltd.
    
    BermudaMSD-Essex GmbH
    
    SwitzerlandMSDJ Holdings (Canada) Inc.
    
    CanadaMSD-SP Ltd.
    
    Great BritainMSP Distribution Services (C) LLC1
    
    NevadaMSP Distribution Services (R) LLC1
    
    NevadaMSP Marketing Services (C) LLC1
    
    NevadaMSP Marketing Services (R) LLC1
    
    NevadaMSP Singapore Company, LLC1
    
    DelawareMSP Technology (U.S.) Company, LLC1
    
    DelawareNeopharmed S.p.A.
    
    ItalyP.T. Merck Sharp & Dohme Indonesia
    
    IndonesiaPasteur Vaccins S.A.1
    
    FranceReadington Investments, Inc.
    
    New JerseyRosetta Inpharmatics LLC
    
    DelawareRuskin Limited
    
    BermudaSanofi Pasteur MSD A/S
    
    DenmarkSanofi Pasteur MSD AG
    
    SwitzerlandSanofi Pasteur MSD Gestion S.A.1
    
    FranceSanofi Pasteur MSD GmbH
    
    AustriaSanofi Pasteur MSD GmbH
    
    GermanySanofi Pasteur MSD Ltd.
    
    Great BritainSanofi Pasteur MSD Ltd.
    
    IrelandSanofi Pasteur MSD N.V./S.A.
    
    BelgiumSanofi Pasteur MSD S.A.
    
    SpainSanofi Pasteur MSD S.p.A.
    
    ItalySanofi Pasteur MSD SNC1
    
    FranceSeneca I LLC
    
    DelawareSharp & Dohme, S.A.
    
    SpainSTELLARx, Inc.
    
    NevadaSuomen MSD Oy
    
    FinlandTELERx Marketing Inc.
    
    PennsylvaniaThe MSD Foundation Limited
    
    Great BritainThomas Morson & Son Limited
    
    Great BritainTradewinds Manufacturing SRL
    
    BarbadosTransrow Manufacturing Ltd.1
    
    BermudaUAB Merck Sharp & Dohme
    
    LithuaniaVariopharm Arzneimittel GmbH
    
    Germany
  1