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Extreme Manufacturing Wo

Frontiers of manufacturing sc

Self-assembly and Biomanufa

John N. Randall PhD

Vice President 

Zyvex Labs LLC

Richardson, Texas 

jrandall@zyvexlabs.com
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Why are the Frontiers o

Manufacturing Science Impo

The importance of the development or acquisition of combined with its effective utilization cannot be overstudies over several decades have demonstrated thtechnology in economic growth. Essentially, the higeconomy must be the high-tech economy. 

Rationales and Mechanisms 

Revitalizing U.S. Manufacturing R&D 

Gregory Tassey 

Senior Economist 

National Institute of Standards and Tech

tassey@nist.gov 

December 2009
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Tassey’s Recommend

(1)Increase the average R&D intensity of the dom

manufacturing sector to 6 percent. 

(2) Adjust the composition of national R&D to emp

long-term, breakthrough research and increase 

sufficient to fund a diversified portfolio of emertechnologies commensurate with the size of theconomy. 

(3) Improve the efficiency of R&D performance an

technology diffusion by increasing the number parks and regional technology clusters and the research portfolio and stakeholder managemeorder to facilitate person-to-person knowledge critical to innovation. 
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Self-assembly and Biomanu

• Physical Manufacturing Processes:

— Produce new materials with useful pro— Improve manufacturing precision — Platform “Generic” technologies— High Flexibility — Reduced waste and energy consumpt

• Value added to US economy 

— Minimize impact of labor cost — Take advantage of sophisticated infras— Require large capital investments 
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New material process exa

Micro-scale Truss Material - Alan J. J

• Customizable material propertie

— Anisotropic — Designed spatial variation— Highly flexible, scalable, low cost — Platform technology enabling ma— Mass customization potential — Additive process - minimal waste
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Atomically Precise Manufac

Our Technology Approa

• APM is the integration of two known exper

— The atomic precision removal of H atoms — Atomic Layer epitaxy: the deposition of a 

• The process which happens in an ultra hig

removing H atoms with a scanning tunneliintroducing a Si containing gas that deposprotected Si atoms. 

• The process is repeated to build up 3D str

1nm

Invariant atomically-precise STM tip, with closed loop computer control, inside UHV system, removes H from Si surface with atomic precision 

In deposition phase, gaseous SiH2

radicals deposit one Si atom wherever H atom is removed (patterned Atomic Layer Epitaxy) 

Aevrest
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Norio Taniguchi’s 

Precision Chart
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Atomically Precise Manufac

Desirable attributes

• Ultimate in Precision • Digital manufacturing • Platform technology 

— Atomically precise CNC Mill — Extensible to many material systems

• Additive process – minimize waste ma• Scalable • Even with a very slow process the nan

volume of near term products with largstart another fortuitous cycle:

— products, investments, improved manufa

efficiency, and a wider range of productsimproved manufacturing efficiency, . . .
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Why am I here? 

• Atomically Precise Manufacturing will happen

where? 

• The Semiconductor Industry is not going to d

— It will start in very small markets— Digital electronics won’t need atomic precisio

• Asian laboratories are already dabbling in Ato

Manufacturing science 

• We are a small and dedicated company that 

support cannot do this in a vacuum

• Our approach might not work • There should be a large program to fund man

ours to develop Atomically Precise Manufactuinfrastructure to support it. 
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What are my hopes 

• US Policy makers enact Tassey’s recommen• We identify manufacturing science and tech

could make a large impact to the future of th

• We recommend that the US Government fun

a partnership of National Labs, Industry, and assure that US companies and workers ben

• In terms of logistics for such programs:

—Tassey: most R&D funding agencies mis

commerce 

—I like the DARPA model 

• We also encourage the USGOV to: 

—Work to strengthen the international IP p—Provide funds to see that the IP develope

internationally

—Ask for a proportional payback of funds i

used offshore