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Exhibit 21 MERCK & CO., INC. SUBSIDIARIES
as of 12/31/04 The following is a list of subsidiaries of the Company, doing business under the name stated. Country or StateName
    
    of IncorporationAlgonquin SarL
    
    LuxembourgAMRAD Pharmaceuticals Pty. Ltd.
    
    AustraliaAton Pharma, Inc.
    
    DelawareBanyu Pharmaceutical Company, Ltd.
    
    JapanBanyu-A.S.C. Co., Ltd.
    
    JapanBlue Jay Investments C.V.
    
    NetherlandsBRC Ltd
    
    BermudaBritish United Turkeys Limited1
    
    Great BritainBUT France s.a.r.l.1
    
    FranceCharles E. Frosst (New Zealand) Ltd
    
    New ZealandCharles E. Frosst (U.K.) Limited
    
    Great BritainChibret A/S
    
    DenmarkChibret Pharmazeutische GmbH
    
    GermanyChippewa Holdings LLC
    
    DelawareCloverleaf International Holdings S.A.
    
    LuxembourgCM Delaware LLC
    
    DelawareComsort, Inc.
    
    DelawareCoophavet S.A.S.1
    
    FranceCoordinated Patient Care Scandinavia AS
    
    NorwayCrosswinds B.V.
    
    NetherlandsDieckmann Arzneimittel GmbH
    
    GermanyEuropean Insurance Risk Excess Limited
    
    IrelandFarmacox-Companhia Farmaceutica, Lda
    
    PortugalFarmasix-Produtos Farmaceuticos, Lda
    
    PortugalFinanciere MSD S.A.S.
    
    FranceFontelabor-Produtos Farmaceuticos, Lda.
    
    PortugalFregenal Holdings S.A.
    
    PanamaFrosst Iberica, S.A.
    
    SpainFrosst Laboratories, Inc.
    
    DelawareFrosst Portuguesa  Produtos Farmaceuticos, Lda.
    
    PortugalHangzhou MSD Pharmaceutical Company Limited1
    
    ChinaHawk and Falcon L.L.C.
    
    DelawareHubbard Nederland B.V.1
    
    NetherlandsInfodoc AS1
    
    NorwayInternational Indemnity Ltd.
    
    BermudaIstituto Di Richerche Di Biologia Molecolare S.p.A.
    
    ItalyIstituto Gentili S.p.A./Inc.
    
    Italy/DelawareJohnson & Johnson  Merck Consumer Pharmaceuticals Company1
    
    New JerseyKBI Inc.
    
    Delaware
 1




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KBI Sub Inc.
    
    DelawareKBI-E Inc.
    
    DelawareKBI-P Inc.
    
    DelawareKiinteisto Oy Viistotie 11
    
    FinlandLaboratoires Merck Sharp & Dohme-Chibret SNC
    
    FranceLaboratorios Abello, S.A.
    
    SpainLaboratorios Biopat, S.A.
    
    SpainLaboratorios Chibret, S.A.
    
    SpainLaboratorios Frosst, S.A.
    
    SpainLaboratorios Neurogard, S.A.
    
    SpainLaboratorios Quimico-Farmaceuticos Chibret, Lda.
    
    PortugalMaple Leaf Holdings SRL
    
    BarbadosMCM Vaccine Co.1
    
    PennsylvaniaMedco de Mexico Managed Care S. de R.L. de C.V.
    
    MexicoMedco Holdings S. de R.L. de C.V.
    
    MexicoMedco Managed Care S.L.
    
    SpainMedco Servicios de Mexico, S. de R.L. de C.V.
    
    MexicoMerck and Company, Incorporated
    
    DelawareMerck Borinquen Holdings, Inc.
    
    DelawareMerck Capital Resources, Inc.
    
    DelawareMerck Capital Ventures, LLC
    
    DelawareMerck Cardiovascular Health Company
    
    NevadaMerck Enterprises Canada, Ltd.
    
    CanadaMerck Finance Co., Inc.
    
    DelawareMerck Foreign Sales Corporation Ltd.
    
    BermudaMerck Frosst Canada & Co.
    
    CanadaMerck Frosst Canada Ltd.
    
    CanadaMerck Hamilton, Inc.
    
    CaliforniaMerck Holdings II Corp.
    
    DelawareMerck Holdings, Inc.
    
    DelawareMerck Institute for Vaccinology
    
    DelawareMerck Investment Co., Inc.
    
    DelawareMerck Liability Management Company
    
    DelawareMerck LMC Cash Management (Bermuda) Ltd.
    
    BermudaMerck LMC Cash Management, Inc.
    
    DelawareMerck Oncology Holdings, Inc.
    
    DelawareMerck Resource Management, Inc.
    
    DelawareMerck Respiratory Health Company
    
    NevadaMerck SH Inc.
    
    DelawareMerck Sharp & Dohme
    
    FranceMerck Sharp & Dohme  Lebanon S.A.L.
    
    LebanonMerck Sharp & Dohme (Argentina) Inc.
    
    DelawareMerck Sharp & Dohme (Asia) Limited
    
    Hong KongMerck Sharp & Dohme (Australia) Pty. Limited
    
    AustraliaMerck Sharp & Dohme (China) Limited
    
    Hong KongMerck Sharp & Dohme (Enterprises) B.V.
    
    NetherlandsMerck Sharp & Dohme (Europe) Inc.
    
    Delaware
 2




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Merck Sharp & Dohme (Holdings) B.V.
    
    NetherlandsMerck Sharp & Dohme (Holdings) Limited
    
    Great BritainMerck Sharp & Dohme (I.A.) Corp.
    
    DelawareMerck Sharp & Dohme (International) Limited
    
    BermudaMerck Sharp & Dohme (Investments) B.V.
    
    NetherlandsMerck Sharp & Dohme (Ireland) Ltd.
    
    BermudaMerck Sharp & Dohme (Israel  1996) Company Ltd.
    
    IsraelMerck Sharp & Dohme (Italia) S.p.A.
    
    ItalyMerck Sharp & Dohme (Middle East) Limited
    
    CyprusMerck Sharp & Dohme (New Zealand) Limited
    
    New ZealandMerck Sharp & Dohme (Panama) S.A.
    
    PanamaMerck Sharp & Dohme (Philippines) Inc.
    
    PhilippinesMerck Sharp & Dohme (Puerto Rico) Ltd.
    
    BermudaMerck Sharp & Dohme (Singapore) Ltd.
    
    BermudaMerck Sharp & Dohme (Sweden) A.B.
    
    SwedenMerck Sharp & Dohme Asia Pacific Services Pte Ltd.
    
    SingaporeMerck Sharp & Dohme B.V.
    
    NetherlandsMerck Sharp & Dohme Chibret A.G.
    
    SwitzerlandMerck Sharp & Dohme Comercializadora, S. de R.L. de C.V.
    
    MexicoMerck Sharp & Dohme d.o.o.
    
    CroatiaMerck Sharp & Dohme de Espana, S.A.
    
    SpainMerck Sharp & Dohme de Mexico, S.A. de C.V.
    
    MexicoMerck Sharp & Dohme de Venezuela S.R.L.
    
    VenezuelaMerck Sharp & Dohme Farmaceutica Ltda.
    
    BrazilMerck Sharp & Dohme Finance Europe Limited
    
    Great BritainMerck Sharp & Dohme GmbH
    
    AustriaMerck Sharp & Dohme Holdings de Mexico, S.A. de C.V.
    
    MexicoMerck Sharp & Dohme IDEA, Inc.
    
    SwitzerlandMerck Sharp & Dohme Industria Quimica e Veterinaria Limitada
    
    BrazilMerck Sharp & Dohme inovativna zdravila d.o.o.
    
    SloveniaMerck Sharp & Dohme International Services B.V.
    
    NetherlandsMerck Sharp & Dohme Ireland (Human Health) Ltd
    
    IrelandMerck Sharp & Dohme Ísland hf
    
    IcelandMerck Sharp & Dohme L.L.C.
    
    Russian FederationMerck Sharp & Dohme Limited
    
    Great BritainMerck Sharp & Dohme of Pakistan Limited
    
    PakistanMerck Sharp & Dohme O.U.
    
    EstoniaMerck Sharp & Dohme Overseas Finance N.V.
    
    Neth. AntillesMerck Sharp & Dohme Peru SRL
    
    PeruMerck Sharp & Dohme Quimica de Puerto Rico, Inc.
    
    DelawareMerck Sharp & Dohme S. de R.L. de C.V.
    
    MexicoMerck Sharp & Dohme SIA
    
    LatviaMerck Sharp & Dohme Tunisie Sarl
    
    TunisiaMerck Sharp & Dohme, Limitada
    
    PortugalMerck Sharp Dohme Ilaclari Limited Sirketi
    
    TurkeyMerck Technology (U.S.) Company, Inc.
    
    NevadaMerck Ventures, Inc.
    
    Delaware
 3




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Merial Animal Health Co. Ltd.1
    
    ChinaMerial Animal Health Ltd1
    
    Great BritainMerial Australia PTY LTD1
    
    AustraliaMerial Argentina SA1
    
    ArgentinaMerial Asia PTE, Ltd.1
    
    SingaporeMerial Belgium1
    
    BelgiumMerial B.V.1
    
    NetherlandsMerial Colombia S.A.1
    
    ColombiaMerial Distribution SAS1
    
    FranceMerial GmbH1
    
    GermanyMerial Hong Kong Limited1
    
    Hong KongMerial (IA) LLP1
    
    Puerto RicoMerial Inc.1
    
    DelawareMerial International Trading (Shanghai) Co., Ltd.1
    
    ChinaMerial Italia SpA1
    
    ItalyMerial Japan, Limited1
    
    JapanMerial Korea Ltd1
    
    KoreaMerial Laboratorios SA1
    
    SpainMerial Limited/LLC1
    
    Great Britain/DelawareMerial Nanjing Animal Health Co. Ltd.1
    
    ChinaMerial New Zealand Limited1
    
    New ZealandMerial Norden A/S1
    
    DenmarkMerial Philippines, Inc.1
    
    PhilippinesMerial Portuguesa  Saude Animal LDA1
    
    PortugalMerial SA1
    
    UruguayMerial SAS1
    
    FranceMerial Saude Animal LTDA1
    
    BrazilMerial Taiwan Co., Ltd.1
    
    TaiwanMerial (Thailand) Ltd1
    
    ThailandMerial Venezuela , C.A.1
    
    VenezuelaMSD (Japan) Co., Ltd.
    
    JapanMSD (Nippon Holdings) BV
    
    NetherlandsMSD (Norge) A/S
    
    NorwayMSD (Proprietary) Limited
    
    South AfricaMSD (Thailand) Ltd.
    
    ThailandMSD Australia Pty Ltd
    
    AustraliaMSD Chibropharm GmbH
    
    GermanyMSD Finance B.V.
    
    NetherlandsMSD Finance Mexico, LLC
    
    DelawareMSD International Holdings, Inc.
    
    DelawareMSD Ireland (Holdings) S.A.
    
    LuxembourgMSD Ireland (Investment) Ltd.
    
    BermudaMSD Korea Ltd.
    
    Korea/DelawareMSD Lakemedel (Scandinavia) Aktiebolog
    
    SwedenMSD Latin America Services Ltd.
    
    BermudaMSD Latin America Services S. de R.L. de C.V.
    
    MexicoMSD Magyarország Kereskedelmi és Szolgáltató Kft
    
    Hungary
 4




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MSD Overseas Manufacturing Co. (Ireland)
    
    IrelandMSD Overseas Manufacturing Co.
    
    BermudaMSD Pembroke Ltd.
    
    BermudaMSD Pharmaceuticals Private Limited
    
    IndiaMSD Polska Sp z.o.o.
    
    PolandMSD S.A. Morocco
    
    MoroccoMSD Sharp & Dohme GmbH
    
    GermanyMSD Somerset Ltd.
    
    BermudaMSD Technology Singapore Pte. Ltd.
    
    SingaporeMSD Technology, L.P.
    
    DelawareMSD Unterstutzungskasse GmbH
    
    GermanyMSD Ventures Singapore Pte. Ltd.
    
    SingaporeMSD Warwick (Manufacturing) Ltd.
    
    BermudaMSD-Essex GmbH
    
    SwitzerlandMSD-SP Ltd.
    
    Great BritainMSP Distribution Services (C) LLC1
    
    NevadaMSP
Distribution Services (R) LLC1
    
    NevadaMSP Marketing Services (C) LLC1
    
    NevadaMSP
Marketing Services (R) LLC1
    
    NevadaMSP Singapore Company, LLC1
    
    DelawareMSP Singapore-Sub, LLC
    
    DelawareMSP Technology (U.S.) Company, LLC1
    
    DelawareNeopharmed S.p.A.
    
    ItalyNippon Merck-Banyu Co., Ltd.
    
    JapanPasteur Vaccins S.A.1
    
    FrancePT Merck Sharp & Dohme Indonesia
    
    IndonesiaReadington Holdings, Inc.
    
    New JerseyReadington Investments, Inc.
    
    New JerseyRosetta Inpharmatics LLC
    
    DelawareRuskin Limited
    
    BermudaSanofi Pasteur MSD A/S
    
    DenmarkSanofi Pasteur MSD Gestion S.A.1
    
    FranceSanofi Pasteur MSD GmbH
    
    AustriaSanofi Pasteur MSD GmbH
    
    GermanySanofi Pasteur MSD Ltd.
    
    Great BritainSanofi Pasteur MSD Ltd.
    
    IrelandSanofi Pasteur MSD N.V./S.A.
    
    BelgiumSanofi Pasteur MSD S.A.
    
    SpainSanofi Pasteur MSD S.p.A.
    
    ItalySanofi
Pasteur MSD
SNC1
    
    FranceSeneca I LLC
    
    DelawareSharp & Dohme, S.A.
    
    SpainSTELLARx, Inc.
    
    NevadaSuomen MSD Oy
    
    FinlandTELERx Marketing Inc.
    
    PennsylvaniaThe MSD Foundation Limited
    
    Great BritainThomas Morson & Son Limited
    
    Great Britain
 5




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Tradewinds Manufacturing SRL
    
    BarbadosTransrow Manufacturing Ltd.1
    
    BermudaUAB Merck Sharp & Dohme
    
    LithuaniaVaripharm Arzneimittel GmbH
    
    Germany
   1
    
    own less than 100% 6