##### Table of Contents

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 10-K/A

(Amendment No. 2)

xANNUAL REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES

EXCHANGE ACT OF 1934

FOR THE FISCAL YEAR ENDED DECEMBER 31, 2010

 ̈TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES

EXCHANGE ACT OF 1934

FOR THE TRANSITION PERIOD FROM
 TO

COMMISSION FILE NUMBER 000-52089

INVIVO THERAPEUTICS HOLDINGS CORP.

(Exact Name of Registrant as specified
in its charter)



|                                                               |  |                                     
|-------------------------------------------------------------- |  | ------------------------------------
|Nevada                                                         |  | 36-4528166                          
|(State or other jurisdiction of incorporation or organization) |  | (I.R.S. Employer Identification No.)
|                                                               | 
|One Broadway, 14thFloor                                        |  |                                     
|Cambridge, Massachusetts                                       |  | 02142                               
|(Address of principal executive offices)                       |  | (Zip Code)                          

Registrants telephone number, including area code: (617) 475-1520

Securities registered pursuant to Section 12(b) of the Act: None

Securities registered pursuant to Section 12(g) of the Act:



|                                           |  |                                          
|------------------------------------------ |  | -----------------------------------------
|Title of each class                        |  | Name of each exchange on which
registered
|Common Stock, par value $0.00001 per share |  | Over-the-Counter Bulletin Board          

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities
Act. Yes  ̈  No x

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes  ̈  No x

Indicate by check mark
whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file
such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes x  No  ̈

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File
required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes  ̈  No  ̈

Indicate by check mark if
disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of the registrants knowledge, in definitive proxy or information statements incorporated by reference
in Part III of this Form 10-K or any amendment to this Form 10-K.    x

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company.
See the definitions of large accelerated filer, accelerated filer and smaller reporting company in Rule 12b-2 of the Exchange Act. (Check one):



|                          |  |                     |  |                                               |  |                            
|------------------------- |  | ------------------- |  | --------------------------------------------- |  | ---------------------------
|Large accelerated filer  ̈ |  | Accelerated filer  ̈ |  | Non-accelerated filer  ̈                       |  | Smaller reporting company x
|                          |  |                     |  | (Do not check if a smaller reporting company) |  |                            

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). Yes  ̈  No x

Our common stock began being
quoted on the OTC Bulletin Board under the symbol NVIV effective October 29, 2010. The approximate aggregate market value of the voting and non-voting common equity held by non-affiliates of the issuer on October 29, 2010 was
$58,547,354 based on a closing price of $2.70 of our common stock on that date.

As of March 21, 2011, the number of shares outstanding of the
registrants common stock, $0.00001 par value per share, was 51,674,712.

DOCUMENTS INCORPORATED BY REFERENCE

None.



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##### Table of Contents

EXPLANATORY NOTE

This Amendment No. 2 (this Amendment) of InVivo Therapeutics Holdings Corp. (the Company) amends the Companys Annual Report on Form 10-K for the fiscal year ended December
31, 2010, originally filed March 24, 2011 and amended on April 29, 2011 (the Form 10-K). This Amendment is being filed in order to amend and restate the Companys consolidated financial statements and accompanying footnotes as of
and for the year ended December 31, 2010 (the 2010 Financials) and other related information included in the Form 10-K.

The
Company is restating its 2010 Financials to correct an error related to the accounting for derivative liabilities. The error related to the process of allocating the proceeds of a financing to two instruments when one of those instruments was a
derivative liability. Originally, the Company allocated the proceeds using the relative fair value of the two instruments with the derivative liability being recorded at its fair value and any difference between the relative fair value and fair
value being charged to a derivative gain or loss upon issuance. Although Generally Accepted Accounting Principles (GAAP) does not address this situation specifically and the Company believed its original accounting to be supported by
GAAP, after discussions with the Securities and Exchange Commission (SEC) Staff the Company determined that its accounting was not consistent with common practice used by other registrants in similar circumstances.

For purposes of this Amendment, and in accordance with Rule 12b-15 under the Securities Exchange Act of 1934, as amended (the Exchange Act),
the following items in the Form 10-K have been amended and restated in their entirety:



| |  |  | Part II, Item 7  Managements Discussion and Analysis of Financial Condition and Results of Operations; and
| | - |  | ------------------------------------------------------------------------------------------------------------



| |  |  | Part II, Item 8  Financial Statements and Supplemental Data.
| | - |  | -------------------------------------------------------------

Additionally, Part IV, Item 15 has been amended to include the Companys currently dated certifications of the Companys principal executive officer and principal financial officer as required
by Sections 302 and 906 of the Sarbanes-Oxley Act of 2002. Other than the items outlined above, there are no changes to the Form 10-K. No attempt has been made in this Form 10-K/A to modify or update the disclosures presented in the Form 10-K,
including the exhibits to the Form 10-K, except as required to reflect the effects of the restatement of the 2010 Financials. Information not affected by the restatement is unchanged and reflects the disclosures made at the time of the original
filing of the Form 10-K on March 24, 2011 and as amended on April 29, 2011. Except as otherwise specifically noted, all information contained herein is as of December 31, 2010 and does not reflect any events or changes that have occurred
subsequent to that date. Accordingly, this Form 10-K/A should be read in conjunction with our filings made with the SEC subsequent to the filing of the Form 10-K, including any amendments to those filings, if any.

The Company is not required to and has not updated any forward-looking statements previously included in the Form 10-K. The Company is also filing an
amendment to its Quarterly Report on Form 10-Q for the quarter ended March 31, 2011 to reflect this restatement. Our previously issued consolidated financial statements as of and for the year ended December 31, 2010, which were filed with the
10-K, should no longer be relied upon.

As used herein, we, us, our or the Company means
InVivo Therapeutics Holdings Corp., together with its consolidated subsidiaries where applicable.



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INVIVO THERAPEUTICS HOLDINGS CORP.

ANNUAL REPORT ON FORM 10-K/A

(Amendment No. 2)

FOR THE YEAR ENDED DECEMBER 31, 2010

TABLE OF CONTENTS



|     |  |                                                                                       |  |      |    | 
|---- |  | ------------------------------------------------------------------------------------- |  | ---- | -- | 
|ITEM |  |                                                                                       |  | Page |   
|     |  | PART II                                                                               |  |      |    | 
|     |  |                                                                                       |  |      |    | 
|7.   |  | Managements Discussion and Analysis of Financial Condition and Results of Operations |  |      | 4  | 
|     |  |                                                                                       |  |      |    | 
|8.   |  | Consolidated Financial Statements and Supplementary Data                              |  |      | 7  | 
|     |  |                                                                                       |  |      |    | 
|     |  | PART IV                                                                               |  |      |    | 
|     |  |                                                                                       |  |      |    | 
|15.  |  | Exhibits, Financial Statement Schedules                                               |  |      | 29 | 
|     |  |                                                                                       |  |      |    | 



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PART II



|Item 7. | MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
|------- | -------------------------------------------------------------------------------------

You should read the following discussion and analysis of financial condition and results of operations together with our consolidated financial statements and accompanying notes included in this annual
report on Form 10-K/A. This discussion contains forward-looking statements that involve risks and uncertainties. Our actual results may differ materially from those anticipated in these forward-looking statements as a result of many important
factors, including those set forth under Risk Factors, Special Note Regarding Forward-Looking Statements and elsewhere in the Form 10-K.

As the result of the Merger and related transactions and the change in business and operations of the Company from a shell company to a biotechnology company, a discussion of the past financial results of
ITHC is not pertinent, and the financial results of InVivo, the acquirer and ongoing operating company, are considered the financial results of the Company on a historical and going-forward basis.

Managements Discussion and Analysis of Financial Condition and Results of Operations

The following managements discussion and analysis should be read in conjunction with the Companys historical consolidated financial statements
and the related notes. The managements discussion and analysis contains forward-looking statements that involve risks and uncertainties, such as statements of our plans, objectives, expectations and intentions. Any statements that are not
statements of historical fact are forward-looking statements. When used, the words believe, plan, intend, anticipate, target, estimate, expect and the like, and/or
future tense or conditional constructions (will, may, could, should, etc.), or similar expressions, identify certain of these forward-looking statements. These forward-looking statements are subject to
risks and uncertainties that could cause actual results or events to differ materially from those expressed or implied by the forward-looking statements in this annual report. The Companys actual results and the timing of events could differ
materially from those anticipated in these forward-looking statements as a result of several factors. The Company does not undertake any obligation to update forward-looking statements to reflect events or circumstances occurring after the date of
this annual report.

The discussion and analysis of the Companys financial condition and results of operations are based on the
Companys financial statements, which the Company has prepared in accordance with U.S. generally accepted accounting principles. The preparation of these financial statements requires the Company to make estimates and assumptions that affect
the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements, as well as the reported revenues and expenses during the reporting periods. On an ongoing basis, the
Company evaluates such estimates and judgments, including those described in greater detail below. The Company bases its estimates on historical experience and on various other factors that the Company believes are reasonable under the
circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates under different assumptions
or conditions.

Critical Accounting Policies and Estimates

Our consolidated financial statements, which appear at page 31, have been prepared in accordance with accounting principles generally accepted in the United States, which require that the Company make
certain assumptions and estimates and, in connection therewith, adopt certain accounting policies. Our significant accounting policies are set forth in Note 2 to our consolidated financial statements. Of those policies, we believe that the
policies discussed below may involve a higher degree of judgment and may be more critical to an accurate reflection of our financial condition and results of operations.



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Stock-Based Compensation

Stock options are generally granted with an exercise price at market value at the date of the grant. The stock options generally expire ten years from the date of grant. Stock option awards vest upon
terms determined by the Board of Directors.

The Company recognizes compensation costs resulting from the issuance of stock-based awards to
employees, non-employees and directors as an expense in the statement of operations over the service period based on a measurement of fair value for each stock-based award.

The fair value of the Companys Common Stock has been determined based on a number of factors including the stage of development of the Company, the value of the Companys Common Stock sold to
outside investors and the market value of other medical device companies in a similar stage of development.

The fair value of each option
grant was estimated as of the date of grant using the Black-Scholes option-pricing model. The fair value is amortized as compensation cost on a straight-line basis over the requisite service period of the awards, which is generally the vesting
period. Due to our limited operating history and limited number of sales of our Common Stock, we estimated our volatility in consideration of a number of factors including the volatility of comparable public companies. The Company uses historical
data, as well as subsequent events occurring prior to the issuance of the consolidated financial statements, to estimate option exercise and employee termination within the valuation model. The expected term of options granted under the
Companys stock plans is based on the average of the contractual term (generally 10 years) and the vesting period (generally 48 months) The risk-free rate is based on the yield of a U.S. Treasury security with a term consistent with
the option.

The following assumptions were used to estimate the fair value of stock options granted using the Black-Scholes option pricing
model:



|                                |  |              |               |  |      |  |            | 
|------------------------------- |  | ------------ | ------------- |  | ---- |  | ---------- | 
|                                |  | December 31, |              
|                                |  | 2010         |               |  | 2009 | 
|Risk-free interest rate         |  |              | 1.63% - 3.05% |  |      |  | 2.68%      | 
|Expected dividend yield         |  |              | 0%            |  |      |  | 0%         | 
|Expected term (employee grants) |  |              | 6.25 years    |  |      |  | 6.25 years | 
|Expected volatility             |  |              | 49.12%        |  |      |  | 50.10%     | 

Derivative Instruments

Certain of our issued and outstanding warrants to purchase Common Stock contain anti-dilution provisions. These warrants do not meet the requirements for classification as equity and are recorded as
derivative warrant liabilities. We use valuation methods and assumptions that consider among other factors the fair value of the underlying stock, risk-free interest rate, volatility, expected life and dividend rates consistent with those discussed
in Stock-Based Compensation above in estimating the fair value for the warrants considered to be derivative warrant liabilities. Such derivative warrant liabilities are initially recorded at fair value with subsequent changes in fair value charged
(credited) to operations in each reporting period. The fair value of the derivative warrant liability is most sensitive to changes in the fair value of the underlying Common Stock and the estimated volatility of our Common Stock.

Results of Operations

Research and
development expenses consist primarily of payments to contract research and development companies and payroll. General and administrative expenses consist primarily of payroll, rent and professional services.



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Comparison of the years ended December 31, 2010 and 2009

Research and Development Expenses

Research and development expenses decreased by $135,000, from $1,808,000 in 2009 to $1,673,000 in 2010. The decrease is primarily attributable to a
reduction in costs of pre-clinical studies offset by stock compensation expense incurred in 2010 of $376,000. In addition, during 2010 the Company received approximately $245,000 as a grant under the IRS Qualifying Therapeutic Discovery Project
(QTDP) program. This amount has been recorded as a reduction in research and development expenses.

General and Administrative
Expenses

General and administrative expenses increased by $888,000, from $836,000 in 2009 to $1,724,000 in 2010. The increase is primarily
attributable to an increase in stock compensation expense of $118,000, approximately $120,000 of costs incurred in the fourth quarter of 2010 associated with operating as a public company, and increases in rent, salary and benefit costs.

Interest expense

Interest expense
increased by $308,000 from $256,000 in 2009 to $564,000 in 2010. The increase is primarily attributable to non-cash interest expense of $317,000 associated with the $500,000 bridge note financing in 2010.

Other Income

Other income in 2009 of
$383,000 resulted from a legal settlement. There was no other income in 2010.

Derivatives Loss

Derivatives loss totaled $3,953,000 for the year ended December 31, 2010 and reflects the change in the fair value of derivative warrant liabilities
during the year. We did not have a derivative warrant liability or derivative (gain) loss in 2009.

Financial Condition, Liquidity and
Capital Resources

Since its inception, the Company has devoted substantially all of its efforts to business planning, research and
development, recruiting management and technical staff, acquiring operating assets and raising capital. Accordingly, the Company is considered to be in the development stage.

Since inception, the Company incurred negative cash flows from operations. The Company has financed its operations primarily through the sale of equity-related securities. At December 31, 2010, the
accumulated deficit was $13,089,000 and the stockholders deficit was $1,853,000.

At December 31, 2010, we had total current assets
of $9,045,000 and current liabilities of $11,232,000 resulting in a working capital deficit of $2,187,000. At December 31, 2010, the Company had total assets of $9,379,000 and total liabilities of $11,232,000, resulting in a stockholders
deficit of $1,853,000.

Net cash used by operating activities for the year ended December 31, 2010 was $2,649,000. The Company raised
$11,423,000 of cash from the sale of equity and $700,000 from the issuance of convertible and bridge notes in the year ended December 31, 2010.

At December 31, 2010, the Company had cash of $8,964,000 and the Company expects the cash to fund its operations at least through March 31, 2012. The Company will need to raise substantial
additional capital to complete its clinical trials, obtain marketing approvals and commercialize its products.

Off Balance Sheet
Arrangements

We have no off balance sheet arrangements, including unrecorded derivative instruments, that have or are reasonably likely to
have a current or future material effect on our financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures, or capital resources. We have certain warrants and options outstanding
but we do not expect to receive sufficient proceeds from the exercise of these instruments unless and until the trading price of our Common Stock is significantly greater than the applicable exercise prices of the options and warrants and mainly
following any necessary registering of underlying securities.



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|Item 8. | CONSOLIDATED FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
|------- | --------------------------------------------------------

LOGO

Report of Independent Registered Public Accounting Firm





To the Board of Directors of InVivo Therapeutics Holdings Corp.:

We have audited the
accompanying consolidated balance sheets of InVivo Therapeutics Holdings Corp. as of December 31, 2010 and 2009, and the related consolidated statements of operations, changes in stockholders deficit and cash flows for the years then
ended and for the period from November 28, 2005 (inception) to December 31, 2010. These financial statements are the responsibility of the Companys management. Our responsibility is to express an opinion on these consolidated
financial statements based on our audits.

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight
Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence
supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We
believe that our audits provide a reasonable basis for our opinion.

In our opinion, the consolidated financial statements referred to above
present fairly, in all material respects, the financial position of the Company as of December 31, 2010 and 2009, and the results of its operations and its cash flows for the years then ended and for the period from November 28, 2005
(inception) to the December 31, 2010, in conformity with accounting principles generally accepted in the United States of America.

/s/
Wolf & Company, P.C.

Boston, Massachusetts

March 24, 2011, except for Notes 9, 11, 12 and 18

as to which the date is June 29, 2011



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InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Consolidated Balance Sheets



|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ------------ | ----------- | - | ---- | - | ---------- | -
|                                                                                                                                                                                  |  | December 31, |            
|                                                                                                                                                                                  |  | 2010         |             |   | 2009 |  
|                                                                                                                                                                                  |  | (Restated)   |             |   |      |  
|ASSETS:                                                                                                                                                                           |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|Current assets:                                                                                                                                                                   |  |              |             |   |      |   |            |  
|Cash and cash equivalents                                                                                                                                                         |  | $            | 8,964,194   |   |      | $ | 226,667    |  
|Prepaid expenses                                                                                                                                                                  |  |              | 81,166      |   |      |   | 10,898     |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|Total current assets                                                                                                                                                              |  |              | 9,045,360   |   |      |   | 237,565    |  
|                                                                                                                                                                                  |  |             
|Property and equipment, net                                                                                                                                                       |  |              | 280,181     |   |      |   | 173,797    |  
|Other assets                                                                                                                                                                      |  |              | 53,639      |   |      |   | 58,639     |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|Total assets                                                                                                                                                                      |  | $            | 9,379,180   |   |      | $ | 470,001    |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|LIABILITIES AND STOCKHOLDERS DEFICIT:                                                                                                                                            |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|Current liabilities:                                                                                                                                                              |  |              |             |   |      |   |            |  
|Accounts payable                                                                                                                                                                  |  | $            | 336,945     |   |      | $ | 81,175     |  
|Accrued interest payable                                                                                                                                                          |  |              | -           |   |      |   | 283,608    |  
|Derivative warrant liability                                                                                                                                                      |  |              | 10,647,190  |   |      |   | -          |  
|Accrued expenses                                                                                                                                                                  |  |              | 247,547     |   |      |   | 293,584    |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|Total current liabilities                                                                                                                                                         |  |              | 11,231,682  |   |      |   | 658,367    |  
|                                                                                                                                                                                  |  |             
|Loans payable                                                                                                                                                                     |  |              | -           |   |      |   | 590,985    |  
|Convertible notes payable                                                                                                                                                         |  |              | -           |   |      |   | 2,840,000  |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|Total liabilities                                                                                                                                                                 |  |              | 11,231,682  |   |      |   | 4,089,352  |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|Commitments and contingencies                                                                                                                                                     |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|Stockholders deficit:                                                                                                                                                            |  |              |             |   |      |   |            |  
|Common stock , $0.00001 par value; authorized 100,000,000 shares, issued and outstanding 51,647,171 and 26,259,515 shares
outstanding at December 31, 2010 and 2009, respectively |  |              | 516         |   |      |   | 263        |  
|Additional paid-in capital                                                                                                                                                        |  |              | 11,235,829  |   |      |   | 1,558,283  |  
|Deficit accumulated during the development stage                                                                                                                                  |  |              | (13,088,847 | ) |      |   | (5,177,897 | )
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|Total stockholders deficit                                                                                                                                                       |  |              | (1,852,502  | ) |      |   | (3,619,351 | )
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  
|                                                                                                                                                                                  |  |             
|Total liabilities and stockholders deficit                                                                                                                                       |  | $            | 9,379,180   |   |      | $ | 470,001    |  
|                                                                                                                                                                                  |  |              |             |   |      |   |            |  

See notes to the consolidated financial statements.



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InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Consolidated Statements of Operations



|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|----------------------------------------------------------------------- |  | ------------------------ | ---------- | - | --------------------------------------------------------- | - | ---------- | ---------- |  | - | ----------- | -
|                                                                        |  | Years Ended December 31, |            |   | Period fromNovember 28,2005(inception) toDecember 31,2010 |  
|                                                                        |  | 2010                     |            |   | 2009                                                      |   |           
|                                                                        |  | (Restated)               |            |   |                                                           |   |            | (Restated) | 
|                                                                        |  |                          |           
|Operating expenses:                                                     |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|Research and development                                                |  | $                        | 1,673,202  |   |                                                           | $ | 1,807,908  |            |  | $ | 4,780,987   |  
|General and administrative                                              |  |                          | 1,724,102  |   |                                                           |   | 835,515    |            |  |   | 3,695,665   |  
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|Total operating expenses                                                |  |                          | 3,397,304  |   |                                                           |   | 2,643,423  |            |  |   | 8,476,652   |  
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|                                                                        |  |                          |           
|Operating loss                                                          |  |                          | (3,397,304 | ) |                                                           |   | (2,643,423 | )          |  |   | (8,476,652  | )
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|Other income (expense):                                                 |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|Other income                                                            |  |                          | -          |   |                                                           |   | 383,000    |            |  |   | 383,000     |  
|Interest income                                                         |  |                          | 3,379      |   |                                                           |   | 282        |            |  |   | 11,290      |  
|Interest expense                                                        |  |                          | (564,443   | ) |                                                           |   | (255,737   | )          |  |   | (1,053,655  | )
|Derivatives losses                                                      |  |                          | (3,952,582 | ) |                                                           |   | -          |            |  |   | (3,952,582  | )
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|Other income (expense), net                                             |  |                          | (4,513,646 | ) |                                                           |   | 127,545    |            |  |   | (4,611,947  | )
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|                                                                        |  |                          |           
|Net loss                                                                |  | $                        | (7,910,950 | ) |                                                           | $ | (2,515,878 | )          |  | $ | (13,088,599 | )
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|                                                                        |  |                          |           
|Net loss per share, basic and diluted                                   |  | $                        | (0.24      | ) |                                                           | $ | (0.10      | )          |  | $ | (0.49       | )
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  
|                                                                        |  |                          |           
|Weighted average number of common shares outstanding, basic and diluted |  |                          | 33,367,239 |   |                                                           |   | 25,496,366 |            |  |   | 26,591,576  |  
|                                                                        |  |                          |            |   |                                                           |   |            |            |  |   |             |  

See notes to the consolidated financial statements.



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InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Consolidated Statements of Changes in Stockholders Deficit



|                                                                                                                                         |  |              |            |  |                          |   |     |                                              |  |   |                           |   |  |   |             |   |  |   |             |  
|---------------------------------------------------------------------------------------------------------------------------------------- |  | ------------ | ---------- |  | ------------------------ | - | --- | -------------------------------------------- |  | - | ------------------------- | - |  | - | ----------- | - |  | - | ----------- | -
|                                                                                                                                         |  | Common Stock |            |  | AdditionalPaid-inCapital |   |     | DeficitAccumulatedDuring theDevelopmentStage |  |   | TotalStockholdersDeficit |  
|                                                                                                                                         |  | Shares       |            |  | Amount                   |   |     |                                              | 
|                                                                                                                                         |  |              |            |  |                         
|Balance on inception date, November 28, 2005                                                                                             |  |              | -          |  |                          | $ | -   |                                              |  | $ | -                         |   |  | $ | -           |   |  | $ | -           |  
|Issuance of founders stock                                                                                                               |  |              | 24,787,080 |  |                          |   | 248 |                                              |  |   | -                         |   |  |   | (248        | ) |  |   | -           |  
|Share-based compensation expense                                                                                                         |  |              | -          |  |                          |   | -   |                                              |  |   | 18,347                    |   |  |   | -           |   |  |   | 18,347      |  
|Net loss                                                                                                                                 |  |              | -          |  |                          |   | -   |                                              |  |   | -                         |   |  |   | (1,097,702  | ) |  |   | (1,097,702  | )
|                                                                                                                                         |  |              |            |  |                          |   |     |                                              |  |   |                           |   |  |   |             |   |  |   |             |  
|                                                                                                                                         |  |              |            |  |                         
|Balance as of December 31, 2007                                                                                                          |  |              | 24,787,080 |  |                          |   | 248 |                                              |  |   | 18,347                    |   |  |   | (1,097,950  | ) |  |   | (1,079,355) |  
|                                                                                                                                         |  |              |            |  |                         
|Share-based compensation expense                                                                                                         |  |              | -          |  |                          |   | -   |                                              |  |   | 24,526                    |   |  |   | -           |   |  |   | 24,526      |  
|Net loss                                                                                                                                 |  |              | -          |  |                          |   | -   |                                              |  |   | -                         |   |  |   | (1,564,069  | ) |  |   | (1,564,069  | )
|                                                                                                                                         |  |              |            |  |                          |   |     |                                              |  |   |                           |   |  |   |             |   |  |   |             |  
|                                                                                                                                         |  |              |            |  |                         
|Balance as of December 31, 2008                                                                                                          |  |              | 24,787,080 |  |                          |   | 248 |                                              |  |   | 42,873                    |   |  |   | (2,662,019  | ) |  |   | (2,618,898  | )
|                                                                                                                                         |  |              |            |  |                         
|Share-based compensation expense                                                                                                         |  |              | -          |  |                          |   | -   |                                              |  |   | 171,059                   |   |  |   | -           |   |  |   | 171,059     |  
|Conversion of convertible notes payable and accrued interest                                                                             |  |              | 1,472,435  |  |                          |   | 15  |                                              |  |   | 1,344,351                 |   |  |   | -           |   |  |   | 1,344,366   |  
|Net loss                                                                                                                                 |  |              | -          |  |                          |   | -   |                                              |  |   | -                         |   |  |   | (2,515,878  | ) |  |   | (2,515,878  | )
|                                                                                                                                         |  |              |            |  |                          |   |     |                                              |  |   |                           |   |  |   |             |   |  |   |             |  
|                                                                                                                                         |  |              |            |  |                         
|Balance as of December 31, 2009                                                                                                          |  |              | 26,259,515 |  |                          |   | 263 |                                              |  |   | 1,558,283                 |   |  |   | (5,177,897  | ) |  |   | (3,619,351  | )
|                                                                                                                                         |  |              |            |  |                         
|Share-based compensation expense                                                                                                         |  |              | -          |  |                          |   | -   |                                              |  |   | 664,908                   |   |  |   | -           |   |  |   | 664,908     |  
|Issuance of common stock in March 2010                                                                                                   |  |              | 1,095,258  |  |                          |   | 10  |                                              |  |   | 999,990                   |   |  |   | -           |   |  |   | 1,000,000   |  
|Conversion of convertible notes payable and accrued interest                                                                             |  |              | 3,792,417  |  |                          |   | 38  |                                              |  |   | 3,328,090                 |   |  |   | -           |   |  |   | 3,328,128   |  
|Issuance of common stock in reverse merger                                                                                               |  |              | 6,999,981  |  |                          |   | 70  |                                              |  |   | (70                       | ) |  |   | -           |   |  |   | -           |  
|Beneficial conversion feature on notes payable                                                                                           |  |              | -          |  |                          |   | -   |                                              |  |   | 272,762                   |   |  |   | -           |   |  |   | 272,762     |  
|Issuance of common stock in private placement, net of stock issuance costs of $2,072,117 and non-cash stock issuance costs of
$5,369,570 |  |              | 12,995,403 |  |                          |   | 130 |                                              |  |   | 3,907,274                 |   |  |   | -           |   |  |   | 3,907,404   |  
|Conversion of convertible bridge notes in conjunction with the private placement                                                         |  |              | 504,597    |  |                          |   | 5   |                                              |  |   | 504,592                   |   |  |   | -           |   |  |   | 504,597     |  
|Net loss                                                                                                                                 |  |              | -          |  |                          |   | -   |                                              |  |   | -                         |   |  |   | (7,910,950  | ) |  |   | (7,910,950  | )
|                                                                                                                                         |  |              |            |  |                          |   |     |                                              |  |   |                           |   |  |   |             |   |  |   |             |  
|Balance as of December 31, 2010 (Restated)                                                                                               |  |              | 51,647,171 |  |                          | $ | 516 |                                              |  | $ | 11,235,829                |   |  | $ | (13,088,847 | ) |  | $ | (1,852,502  | )
|                                                                                                                                         |  |              |            |  |                          |   |     |                                              |  |   |                           |   |  |   |             |   |  |   |             |  

See notes to the consolidated financial statements.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Consolidated Statements of Cash Flows



|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|--------------------------------------------------------------------------- |  | ------------------------ | ---------- | - | --------------------------------------------------------- | - | ---------- | ---------- |  | - | ------------ | -
|                                                                            |  | Years Ended December 31, |            |   | Period
fromNovember 28,2005(inception) toDecember 31,2010 |  
|                                                                            |  | 2010                     |            |   | 2009                                                      |   |           
|                                                                            |  | (Restated)               |            |   |                                                           |   |            | (Restated) | 
|Cash flows from operating activities:                                       |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Net loss                                                                    |  | $                        | (7,910,950 | ) |                                                           | $ | (2,515,878 | )          |  | $ | (13,088,599) |  
|Adjustments to reconcile net loss to net cash used in operating activities: |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Depreciation and amortization expense                                       |  |                          | 44,878     |   |                                                           |   | 32,084     |            |  |   | 92,965       |  
|Non-cash derivatives loss                                                   |  |                          | 3,952,582  |   |                                                           |   | -          |            |  |   | 3,952,582    |  
|Non-cash interest expense                                                   |  |                          | 528,535    |   |                                                           |   | 221,899    |            |  |   | 962,834      |  
|Share-based compensation expense                                            |  |                          | 664,908    |   |                                                           |   | 171,059    |            |  |   | 878,840      |  
|Changes in operating assets and liabilities:                                |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Prepaid expenses                                                            |  |                          | (70,268    | ) |                                                           |   | 2,036      |            |  |   | (81,166      | )
|Other assets                                                                |  |                          | -          |   |                                                           |   | -          |            |  |   | (75,000      | )
|Accounts payable                                                            |  |                          | 255,770    |   |                                                           |   | (23,248    | )          |  |   | 336,945      |  
|Accrued interest payable                                                    |  |                          | (67,931    | ) |                                                           |   | 33,598     |            |  |   | (15,256      | )
|Accrued expenses                                                            |  |                          | (46,037    | ) |                                                           |   | 179,426    |            |  |   | 247,547      |  
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Net cash used in operating activities                                       |  |                          | (2,648,513 | ) |                                                           |   | (1,899,024 | )          |  |   | (6,788,308   | )
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|                                                                            |  |                          |           
|Cash flows from investing activities:                                       |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Purchases of property and equipment                                         |  |                          | (146,262   | ) |                                                           |   | (174,898   | )          |  |   | (351,785     | )
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Net cash used in investing activities                                       |  |                          | (146,262   | ) |                                                           |   | (174,898   | )          |  |   | (351,785     | )
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Cash flows from financing activities:                                       |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Proceeds from issuance of convertible notes payable                         |  |                          | 200,000    |   |                                                           |   | 1,580,000  |            |  |   | 4,181,000    |  
|Proceeds from convertible bridge notes                                      |  |                          | 500,000    |   |                                                           |   | -          |            |  |   | 500,000      |  
|(Repayment of) proceeds from loans payable                                  |  |                          | (590,985   | ) |                                                           |   | 513,800    |            |  |   | -            |  
|Proceeds from issuance of common stock and warrants                         |  |                          | 11,423,287 |   |                                                           |   | -          |            |  |   | 11,423,287   |  
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Net cash provided by financing activities                                   |  |                          | 11,532,302 |   |                                                           |   | 2,093,800  |            |  |   | 16,104,287   |  
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|                                                                            |  |                          |           
|Increase in cash and cash equivalents                                       |  |                          | 8,737,527  |   |                                                           |   | 19,878     |            |  |   | 8,964,194    |  
|                                                                            |  |                          |           
|Cash and cash equivalents at beginning of period                            |  |                          | 226,667    |   |                                                           |   | 206,789    |            |  |   | -            |  
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  
|Cash and cash equivalents at end of period                                  |  | $                        | 8,964,194  |   |                                                           | $ | 226,667    |            |  | $ | 8,964,194    |  
|                                                                            |  |                          |            |   |                                                           |   |            |            |  |   |              |  

(continued)

See notes to the consolidated financial statements.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Consolidated Statements of Cash Flows (Concluded)



|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|------------------------------------------------------------------------------------ |  | ------------------------ | --------- | - | --------------------------------------------------------- | - | --------- |  |  | - | --------- | -
|                                                                                     |  | Years Ended December 31, |           |   | Period
fromNovember 28,2005(inception) toDecember 31,2010 |  
|                                                                                     |  | 2010                     |           |   | 2009                                                      |   |          
|                                                                                     |  |                          |          
|Supplemental disclosure of cash flow information and non-cash transactions:          |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|Cash paid for interest                                                               |  | $                        | (34,204   | ) |                                                           | $ | -         |  |  | $ | (34,204   | )
|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|                                                                                     |  |                          |          
|Conversion of convertible notes payable and accrued interest into common stock       |  | $                        | 3,328,128 |   |                                                           | $ | 1,344,366 |  |  | $ | 4,672,484 |  
|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|                                                                                     |  |                          |          
|Conversion of convertible bridge note payable and accrued interest into common stock |  | $                        | 504,597   |   |                                                           | $ | -         |  |  | $ | 504,597   |  
|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|                                                                                     |  |                          |          
|Beneficial conversion feature on convertible and bridge notes payable                |  | $                        | 272,762   |   |                                                           | $ | -         |  |  | $ | 134,410   |  
|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|                                                                                     |  |                          |          
|Fair value of warrants issued in connection with bridge notes payable                |  | $                        | 178,726   |   |                                                           | $ | -         |  |  | $ | 178,726   |  
|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  
|                                                                                     |  |                          |          
|Issuance of founders shares                                                          |  | $                        | -         |   |                                                           | $ | -         |  |  | $ | 248       |  
|                                                                                     |  |                          |           |   |                                                           |   |           |  |  |   |           |  

See notes to the consolidated financial statements.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements

Years Ended December 31, 2010 and
2009, and the Period from

November 28, 2005 (Inception) through December 31, 2010



|1. | NATURE OF OPERATIONS
|-- | --------------------

Business

InVivo Therapeutics Corporation (InVivo) was incorporated on November 28, 2005 under the laws of the State of Delaware. InVivo is developing and commercializing biopolymer scaffolding
devices for the treatment of spinal cord injuries. The biopolymer devices are designed to protect the damaged spinal cord from further secondary injury and promote neuroplasticity, a process where functional recovery can occur through the rerouting
of signaling pathways to the spared healthy tissue.

Since its inception, InVivo has devoted substantially all of its efforts
to business planning, research and development, recruiting management and technical staff, acquiring operating assets and raising capital. Accordingly, InVivo is considered to be in the development stage.

Reverse Merger

On October 26, 2010, InVivo completed a reverse merger transaction (the Merger) with InVivo Therapeutics Holdings Corporation (formerly Design Source, Inc.) (ITHC), a publicly
traded company incorporated under the laws of the State of Nevada. InVivo became a wholly owned subsidiary of ITHC, which continues to operate the business of InVivo. As part of the Merger, ITHC issued 31,147,190 shares of its Common Stock to the
holders of InVivo common stock on October 26, 2010 in exchange for the 2,261,862 outstanding common shares of InVivo and also issued 500,000 shares to its legal counsel in consideration for legal services provided. All share and per share
amounts presented in these consolidated financial statements have been retroactively restated to reflect the 13.7706 exchange ratio of InVivo shares for ITHC shares in the Merger. Immediately prior to the Merger, ITHC had 6,999,981 shares of Common
Stock outstanding.

The Merger was accounted for as a reverse merger, and InVivo is deemed to be the accounting
acquirer. The Merger was recorded as a reverse recapitalization, equivalent to the issuance of common stock by InVivo for the net monetary assets of ITHC accompanied by a recapitalization. At the date of the Merger, the 6,999,981 outstanding ITHC
shares are reflected as an issuance of InVivo common stock to the prior shareholders of ITHC. ITHC had no net monetary assets as of the Merger so this issuance was recorded as a reclassification between additional paid-in capital and par value of
Common Stock.

The historical consolidated financial statements are those of InVivo as the accounting acquirer. The
post-merger combination of ITHC and InVivo is referred to throughout these notes to consolidated financial statements as the Company. Subsequent to the Merger, the Company completed three closings as part of a private placement (see Note
11).

On October 26, 2010, in connection with the Merger described above, ITHC transferred all of its operating assets
and liabilities to its wholly-owned subsidiary, D Source Split Corp., a company organized under the laws of Nevada (DSSC). DSSC was then split-off from ITHC through the sale of all outstanding shares of DSSC (the Split-Off).
The assets and liabilities of ITHC were transferred to the Split-Off Shareholders in the Split-Off. ITHC executed a split off agreement with the Split-Off Shareholders which obligates the Split-Off Shareholders to assume all prior liabilities
associated with Design Source, Inc. and all DSSC liabilities. In conjunction with the Split-Off, certain shareholders of



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | NATURE OF OPERATIONS (concluded)
| | --------------------------------



ITHC surrendered for cancellation shares of ITHC Common Stock for no additional consideration. The purpose of the Split-Off was to make ITHC a shell company with no assets or liabilities in order
to facilitate the Merger. Although all transactions related to the Merger occurred simultaneously, the Split-Off, including the cancellation of shares, was considered to have occurred immediately prior to the Merger for accounting purposes. As the
accounting acquiree in a reverse merger with a shell company, the historical financial statements of ITHC are not presented and these ITHC transactions are not reflected in the Companys accompanying consolidated financial statements.



|2. | SIGNIFICANT ACCOUNTING POLICIES
|-- | -------------------------------

A summary of the significant accounting policies followed by the Company in the preparation of the financial statements is as follows:

Use of estimates

The process of preparing financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect
the reported amounts of assets and liabilities and disclosure of assets and liabilities at the date of financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those
estimates and changes in estimates may occur.

Principles of Consolidation

The consolidated financial statements include the accounts of InVivo Therapeutics Holdings Corp. and its wholly-owned subsidiary, InVivo
Therapeutics Corporation. All significant intercompany balances and transactions have been eliminated in consolidation.

Cash and cash equivalents

The Company considers all highly liquid investments with maturities of three months or less at the date of purchase to be cash equivalents.

Property and equipment

Property and equipment are carried at cost. Depreciation expense is provided over the estimated useful lives of the assets using the straight-line method. A summary of the estimated useful lives is as
follows:



|                           |  |                      
|-------------------------- |  | ---------------------
|Classification             |  | Estimated Useful Life
|                           | 
|Computer hardware          |  | 5 years              
|Software                   |  | 3 years              
|Research and lab equipment |  | 5 years              

Depreciation expense for the years ended December 31, 2010 and 2009 was $39,878 and $27,084,
respectively. Maintenance and repairs are charged to expense as incurred, while any additions or improvements are capitalized.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | SIGNIFICANT ACCOUNTING POLICIES (continued)
| | -------------------------------------------



Research and development expenses

Costs incurred for research and development are expensed as incurred. During 2010, the Company applied for a grant under the IRS
Qualifying Therapeutic Discovery Project (QTDP) program. The application was approved and the Company received a grant for $244,500 under the program. This amount has been recorded as a reduction in research and development expenses.

Concentrations of credit risk

The Company has no significant off-balance-sheet concentration of credit risk such as foreign exchange contracts, option contracts or other hedging arrangements. The Company may from time to time have
cash in banks in excess of FDIC insurance limits.

Segment Information

Operating segments are identified as components of an enterprise about which separate discrete financial information is available for
evaluation by the chief operating decision maker, or decision making group, in making decisions regarding resource allocation and assessing performance. To date, the Company has viewed its operations and manages its business as principally one
operating segment, which is developing and commercializing biopolymer scaffolding devices for the treatment of spinal cord injuries. As of December 31, 2010 and 2009, all of the Companys assets were located in the United States.

Income taxes

For federal and state income taxes, deferred tax assets and liabilities are recognized based upon temporary differences between the financial statement and the tax basis of assets and liabilities.
Deferred income taxes are based upon prescribed rates and enacted laws applicable to periods in which differences are expected to reverse. A valuation allowance is recorded when it is more likely than not that some portion or all of the deferred tax
assets will not be realized. Accordingly, the Company provides a valuation allowance, if necessary, to reduce deferred tax assets to amounts that are realizable. Tax positions taken or expected to be taken in the course of preparing the
Companys tax returns are required to be evaluated to determine whether the tax positions are more-likely-than-not of being sustained by the applicable tax authority. Tax positions not deemed to meet a more-likely-than-not threshold
would be recorded as a tax expense in the current year. There were no uncertain tax positions that require accrual or disclosure to the financial statements as of December 31, 2010 or December 31, 2009.

Impairment of long-lived assets

The Company continually monitors events and changes in circumstances that could indicate that carrying amounts of long-lived assets may not be recoverable. An impairment loss is recognized when expected
cash flows are less than an assets carrying value. Accordingly, when indicators of impairment are present, the Company evaluates the carrying value of such assets in relation to the operating performance and future undiscounted cash flows of
the underlying assets. The Companys policy is to record an impairment loss when it is determined that the carrying value of the asset may not be recoverable. No impairment charges were recorded for the years ended December 31, 2010 and
2009.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | SIGNIFICANT ACCOUNTING POLICIES (continued)
| | -------------------------------------------



Share-based payments

The Company recognizes compensation costs resulting from the issuance of stock-based awards to employees, non-employees and directors as
an expense in the statement of operations over the service period based on a measurement of fair value for each stock-based award. The fair value of each option grant is estimated as of the date of grant using the Black-Scholes option-pricing model.
The fair value is amortized as compensation cost on a straight-line basis over the requisite service period of the awards, which is generally the vesting period. Due to its limited operating history, limited number of sales of its Common Stock and
limited history of its shares being publicly traded, the Company estimates its volatility in consideration of a number of factors including the volatility of comparable public companies.

Derivative Instruments

The Company generally does not use derivative instruments to hedge exposures to cash-flow or market risks; however, certain warrants to purchase Common Stock that do not meet the requirements for
classification as equity are classified as liabilities. In such instances, net-cash settlement is assumed for financial reporting purposes, even when the terms of the underlying contracts do not provide for a net-cash settlement. Such financial
instruments are initially recorded at fair value with subsequent changes in fair value charged (credited) to operations in each reporting period. If these instruments subsequently meet the requirements for classification as equity, the Company
reclassifies the fair value to equity.

Net Loss per Common Share

Basic and diluted net loss per share of Common Stock has been computed by dividing the net loss in each period by the weighted average
number of shares of Common Stock outstanding during such period. For the periods presented, options, warrants and convertible securities were anti-dilutive and therefore excluded from diluted loss per share calculations.

Registration Payment Arrangements

At each reporting date, the Company assesses the probability of it transferring consideration under its registration payment arrangements. If at any time it determines that such an event is probable and
the amount can be reasonably estimated, the amount of such an obligation is recognized as a liability with a charge to earnings. Future changes in that liability will also be charged (credited) to earnings. At the date the Registration Rights
Agreement (see Note 11) was entered into and at December 31, 2010, the Company did not conclude that it was probable that they will be obligated to transfer any consideration under the terms of this Registration Rights Agreement.

Recent Accounting Pronouncements

In October 2009, the Financial Accounting Standards Board (FASB) issued two related accounting pronouncements, Accounting Standards Update (ASU) 2009-13 and ASU 2009-14, relating
to revenue recognition. One pronouncement provides guidance on allocating the consideration in a multiple-deliverable revenue arrangement and requires additional disclosure, while the other pronouncement provides guidance specific to revenue
arrangements that include software elements. Both of these pronouncements are effective prospectively for revenue arrangements entered into or materially modified



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | SIGNIFICANT ACCOUNTING POLICIES (concluded)
| | -------------------------------------------



in fiscal years beginning on or after June 15, 2010 and both must be adopted together. The Company does not expect the adoption of these pronouncements to have a material impact on its
consolidated financial statements.

In January 2010, the FASB issued ASU 2010-06, Fair Value Measurements and Disclosures
(Topic 820), Improving Disclosures about Fair Value Measurements. This Update requires new disclosures and clarifies existing disclosures regarding recurring and nonrecurring fair value measurements to provide increased transparency to users of the
financial statements. The new disclosures and clarification of existing disclosures are effective for interim and annual periods beginning after December 15, 2009, except for the disclosures pertaining to the roll forward of activity for Level
3 fair value measurements, which are effective for fiscal years beginning after December 15, 2010, and for interim periods within those fiscal years. The adoption of this Update on January 1, 2010 did not have a material impact on the
Companys consolidated financial statements.

In April 2010, the FASB issued ASU 2010-17, Revenue Recognition 
Milestone Method. ASU 2010-17 provides guidance in applying the milestone method of revenue recognition to research or development arrangements. Under this guidance, management may recognize revenue contingent upon the achievement of a milestone in
its entirety, in the period in which the milestone is achieved, only if the milestone meets all the criteria within the guidance to be considered substantive. This ASU is effective on a prospective basis for research and development milestones
achieved in fiscal years, beginning on or after June 15, 2010. Early adoption is permitted; however, the Company has elected to implement ASU 2010-17 prospectively, and as a result, the effect of this guidance will be limited to future
transactions. The Company does not expect the adoption of this pronouncement to have a material impact on its consolidated financial statements.



|3. | PROPERTY AND EQUIPMENT
|-- | ----------------------

Property and equipment consisted of the following:



|                               |  |              |         |   |      |   |         |  
|------------------------------ |  | ------------ | ------- | - | ---- | - | ------- | -
|                               |  | December 31, |        
|                               |  | 2010         |         |   | 2009 |  
|Computer software and hardware |  | $            | 91,057  |   |      | $ | 47,668  |  
|Research and lab equipment     |  |              | 260,728 |   |      |   | 157,855 |  
|Less accumulated depreciation  |  |              | (71,604 | ) |      |   | (31,726 | )
|                               |  |              |         |   |      |   |         |  
|                               |  |             
|                               |  | $            | 280,181 |   |      | $ | 173,797 |  
|                               |  |              |         |   |      |   |         |  



|4. | OTHER ASSETS
|-- | ------------

Other
assets consist of a patent licensing fee paid to license intellectual property (see Note 16). The Company is amortizing the license fee to research and development over its 15-year term.



|                         |  |              |         |   |      |   |         |  
|------------------------ |  | ------------ | ------- | - | ---- | - | ------- | -
|                         |  | December 31, |        
|                         |  | 2010         |         |   | 2009 |  
|Patent licensing fee     |  | $            | 75,000  |   |      | $ | 75,000  |  
|Accumulated amortization |  |              | (21,361 | ) |      |   | (16,361 | )
|                         |  |              |         |   |      |   |         |  
|                         |  |             
|                         |  | $            | 53,639  |   |      | $ | 58,639  |  
|                         |  |              |         |   |      |   |         |  

Amortization expense was $5,000 in each of the years ended December 31, 2010 and 2009.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



|5. | ACCRUED EXPENSES
|-- | ----------------



Accrued expenses consisted of the following:



|                       |  |              |         |  |      |   |         | 
|---------------------- |  | ------------ | ------- |  | ---- | - | ------- | 
|                       |  | December 31, |        
|                       |  | 2010         |         |  | 2009 |  
|Other accrued expenses |  | $            | 45,053  |  |      | $ | 138,750 | 
|Accrued payroll        |  |              | 179,629 |  |      |   | 18,969  | 
|Accrued vacation       |  |              | 22,865  |  |      |   | 15,865  | 
|Deferred compensation  |  |              | -       |  |      |   | 120,000 | 
|                       |  |              |         |  |      |   |         | 
|                       |  |             
|                       |  | $            | 247,547 |  |      | $ | 293,584 | 
|                       |  |              |         |  |      |   |         | 

Deferred compensation represented amounts owed to the Chief Executive Officer (CEO) with
respect to annual bonuses granted but not paid. All deferred compensation was paid in the year ended December 31, 2010.



|6. | FAIR VALUES OF ASSETS AND LIABILITIES
|-- | -------------------------------------

The Company groups its assets and liabilities generally measured at fair value in three levels, based on the markets in which the assets and liabilities are traded and the reliability of the assumptions
used to determine fair value.

Level 1  Valuation is based on quoted prices in active markets for identical assets or
liabilities. Level 1 assets and liabilities generally include debt and equity securities that are traded in an active exchange market. Valuations are obtained from readily available pricing sources for market transactions involving identical assets
or liabilities.

Level 2  Valuation is based on observable inputs other than Level 1 prices, such as quoted prices for
similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.

Level 3  Valuation is based on unobservable inputs that are supported by little or no market activity and that are significant to
the fair value of the assets or liabilities. Level 3 assets and liabilities include financial instruments whose value is determined using pricing models, discounted cash flow methodologies, or similar techniques, as well as instruments for which the
determination of fair value requires significant management judgment or estimation.

The Company uses valuation methods and
assumptions that consider among other factors the fair value of the underlying stock, risk-free interest rate, volatility, expected life and dividend rates in estimating fair value for the warrants considered to be derivative instruments.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | FAIR VALUES OF ASSETS AND LIABILITIES (concluded)
| | -------------------------------------------------



Assets and liabilities measured at fair value on a recurring basis are summarized below:



|                             |  |                   |   |  |         |   |            |         |  |  |            |  |  |   |            | 
|---------------------------- |  | ----------------- | - |  | ------- | - | ---------- | ------- |  |  | ---------- |  |  | - | ---------- | 
|                             |  | December 31, 2010 |  
|                             |  | Level 1           |   |  | Level 2 |   |            | Level 3 |  |  | Fair Value | 
|Liabilities:                 |  |                   |   |  |         |   |            |         |  |  |            |  |  |   |            | 
|Derivative warrant liability |  | $                 | - |  |         | $ | 10,647,190 |         |  |  | -          |  |  | $ | 10,647,190 | 
|                             |  |                   |   |  |         |   |            |         |  |  |            |  |  |   |            | 
|                             | 
|                             |  | December 31, 2009 |  
|                             |  | Level 1           |   |  | Level 2 |   |            | Level 3 |  |  | FairValue  | 
|Liabilities:                 |  |                   |   |  |         |   |            |         |  |  |            |  |  |   |            | 
|Derivative warrant liability |  | $                 | - |  |         | $ | -          |         |  |  | -          |  |  | $ | -          | 
|                             |  |                   |   |  |         |   |            |         |  |  |            |  |  |   |            | 



|7. | LOANS PAYABLE
|-- | -------------

Loans
payable consisted of the following:



|                                               |  |              |   |  |      |   |         | 
|---------------------------------------------- |  | ------------ | - |  | ---- | - | ------- | 
|                                               |  | December 31, |  
|                                               |  | 2010         |   |  | 2009 |  
|Advances from related party                    |  | $            | - |  |      | $ | 90,985  | 
|Note payable-Massachusetts Life Science Center |  |              | - |  |      |   | 500,000 | 
|                                               |  |              |   |  |      |   |         | 
|                                               |  | $            | - |  |      | $ | 590,985 | 
|                                               |  |              |   |  |      |   |         | 

Advances from related party represent cash advances received from CEO and majority shareholder which
permitted the Company to continue to fund its operations until it raised additional capital. Interest accrued on these advances at an annual rate of 8%. Interest expense related to Advances from related party was $3,227 and $8,437 in the years
ended December 31, 2010 and 2009, respectively.

The Company issued a $500,000 Note Payable in June 2009 to the
Massachusetts Life Science Center, an independent public agency of the State of Massachusetts. The Company received the $500,000 of funding from the Massachusetts Life Science Accelerator Program which was established for the purpose of providing
seed capital to promising early stage life science companies. The terms of the Note Payable called for full repayment upon the earlier of five years, the sale of the Company or a financing that raises minimum net proceeds of $5,000,000. Interest
accrued on the Note Payable at an annual rate of 10% and is payable at maturity. Interest expense related to the Note Payable was $42,726, and $25,205 for the years ended December 31, 2010 and 2009, respectively. In October 2010, the $500,000
loan was repaid together with accrued interest of $67,931.



|8. | CONVERTIBLE NOTES PAYABLE
|-- | -------------------------

Since inception, the Company issued Convertible Notes Payable to investors totaling $4,181,000. In the years ended December 31, 2010
and 2009, these notes provided cash proceeds of $200,000 and $1,580,000, respectively. The terms of the Convertible Notes Payable include interest at 8% and stipulated



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | CONVERTIBLE NOTES PAYABLE (concluded)
| | -------------------------------------



that the notes convert into shares of Common Stock upon the earlier of maturity of the notes or the completion of a Financing Round, a single financing or a series of related financings that
raised a minimum of $4,000,000 or $5,000,000 depending on the terms of the individual notes. The notes convert at the offering price of such financing.

Certain of the notes entitled the holders to receive either a 10% or 20% discount on the conversion price if the notes were converted in connection with a Financing Round prior to the maturity date. The
Company initially assessed whether a beneficial conversion feature existed on the issuance date based on the difference, if any, between the conversion price and the fair value of the Common Stock. The Company assumed the most favorable conversion
price that would be in effect assuming no changes to the circumstances other than the passage of time. Based on this analysis, the Company concluded that there was no beneficial conversion feature at issuance.

However, the conversion terms are subject to change in the event of a Financing Round. Therefore, at the commitment date, the Company
measured the contingent beneficial conversion feature based on the intrinsic value of the fixed percentage discount but such beneficial conversion feature was not recognized unless and until the triggering event occurs. This amount was determined by
dividing the face amount of the convertible notes by the discount factor (0.90 or 0.80).

During the year ended
December 31, 2009, Convertible Notes Payable with a principal balance of $1,141,000 and accrued interest payable of $203,366 converted at maturity into 1,472,435 shares of Common Stock.

In March 2010, the Company completed a series of financings that met the definition of a Financing Round which accelerated the conversion
of certain notes prior to their maturity dates triggering the discount provisions discussed above.

During the year ended
December 31, 2010, the remaining outstanding Convertible Notes Payable of $3,040,000 and accrued interest payable of $288,128 converted into 3,792,417 shares of Common Stock in conjunction with the Financing Round. As of December 31, 2010,
all of the Convertible Notes Payable had been converted into Common Stock.

As a result of the Financing Round in March 2010,
the Company recorded the previously measured contingent beneficial conversion feature as a discount on the notes and additional paid-in capital. As the discount occurred simultaneously with the conversion of the notes, the discount was immediately
charged to non-cash interest expense. Accordingly, during the year ended December 31, 2010, the Company recorded a beneficial conversion feature and related non-cash interest expense of $134,410.

Interest accrued on the outstanding balances at an annual rate of 8%. At the election of the Company, the accrued interest was to be paid
in cash or in Common Stock at the time the notes were converted to Common Stock. For the year ended December 31, 2010 and 2009, the Company accrued interest expense on the notes of $62,385 and $169,573, respectively.



|9. | BRIDGE NOTES PAYABLE
|-- | --------------------

From July through September 2010, the Company raised $500,000 from the sale of 6% convertible promissory notes (the Bridge
Notes). The Bridge Notes pay interest at 6% and had a stated maturity date of December 31, 2010. The Bridge Notes and all accrued interest were only convertible in the event of a



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | BRIDGE NOTES PAYABLE (concluded)
| | --------------------------------



Qualified Next Round Financing, as defined, at 100% of the price in that Qualified Next Round Financing. Otherwise, the Bridge Notes were to be repaid at their maturity date. In connection with
the Bridge Notes, the Company also issued to Bridge Notes investors warrants to purchase 500,000 shares of Common Stock (the Bridge Warrants). The Bridge Warrants are exercisable for a period of five years with an exercise price of $1.00
per share.

In order to record the Bridge Notes and Bridge Warrants, the Company allocated the proceeds first to the fair
value of the Bridge Warrants. The residual was then allocated to the Bridge Notes. As a result, the Company allocated $138,352 to the Bridge Warrants with the remainder of the proceeds allocated to the Bridge Notes. The total discount on the Bridge
Notes of $138,352 was recognized as non-cash interest expense over the term of the Bridge Notes and was expensed to interest expense in 2010.

In order to determine if a beneficial conversion feature existed, the Company compared the effective conversion price of the Bridge Notes to the commitment date fair value of the Common Stock and
determined a beneficial conversion feature in the amount of $138,352. However, since the Bridge Notes were only convertible in the event of a Qualified Next Round Financing, this was determined to be a contingent beneficial conversion feature not to
be recognized unless and until the triggering event occurs.

In October 2010, the Company completed a private placement of
Common Stock (see Note 11) which met the definition of a Qualified Next Round Financing. The Bridge Notes and accrued interest of $4,597 converted into 504,597 Units, with each unit consisting of one share of Common Stock and one warrant to purchase
Common Stock at $1.40 per share. As a result of the Qualified Next Round Financing,the contingent beneficial conversion feature of $138,352 was recognized as a further discount on the Bridge Notes and additional paid-in capital on the date
of conversion. Since the conversion took place simultaneously with the Qualified Next Round Financing, this discount of $138,352 was immediately charged to non-cash interest expense.

The Company engaged a registered broker-dealer as a placement agent (the Placement Agent) in conjunction with the Bridge
Notes. As compensation, the Placement Agent received a warrant to purchase 100,000 shares of Common Stock at an exercise price of $1.00 per share. The fair value of the warrants issued to the Placement Agent of $40,373 was recorded as a debt
issuance cost and amortized to non-cash interest expense over the term of the Bridge Notes.

For the year ended
December 31, 2010, interest expense related to the Bridge Notes, including amortization of the discount and debt issuance costs, was $321,674.

The warrants issued to the Bridge Notes investors and the Placement Agent have provisions that include anti-dilution protection and under certain conditions, grant the right to the holder to request the
Company to repurchase the warrant, and are therefore accounted for as derivative liabilities (see Note 11).



|10. | INCOME TAXES
|--- | ------------

No
provision or benefit for federal or state income taxes has been recorded, as the Company has incurred a net loss for all of the periods presented, and the Company has provided a valuation allowance against its deferred tax assets.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | INCOME TAXES (continued)
| | ------------------------



At December 31, 2010 and 2009, the Company had federal and Massachusetts net
operating loss carryforwards of approximately $8,719,000, and $5,491,000, respectively, of which federal carryforwards will expire in varying amounts beginning in 2021. Massachusetts net operating losses begin to expire in 2011. Utilization of net
operating losses may be subject to substantial annual limitations due to the change in ownership provisions of the Internal Revenue Code, and similar state provisions. The annual limitations may result in the expiration of net operating
losses before utilization. The Company also had research and development tax credit carryforwards at December 31, 2010 and 2009 of approximately $238,000 and $154,000, respectively, which will begin to expire in 2018 unless previously
utilized.

Significant components of the Companys net deferred tax asset are as follows:



|                                             |  |              |            |   |      |   |            |  
|-------------------------------------------- |  | ------------ | ---------- | - | ---- | - | ---------- | -
|                                             |  | December 31, |           
|                                             |  | 2010         |            |   | 2009 |  
|Net operating loss carryforward              |  | $            | 3,016,062  |   |      | $ | 1,612,965  |  
|Research and development credit carryforward |  |              | 120,315    |   |      |   | 154,077    |  
|Stock based Compensation                     |  |              | 382,295    |   |      |   | 86,150     |  
|Deferred compensation                        |  |              | 52,200     |   |      |   | 48,324     |  
|Accrued interest                             |  |              |           |   |      |   | 114,209    |  
|Charitable contributions                     |  |              | 17,751     |   |      |   | 3,533      |  
|                                             |  |              |            |   |      |   |            |  
|Subtotal                                     |  |              | 3,588,623  |   |      |   | 2,019,258  |  
|Valuation allowance                          |  |              | (3,588,623 | ) |      |   | (2,019,258 | )
|                                             |  |              |            |   |      |   |            |  
|Net deferred tax asset                       |  | $            | -          |   |      | $ | -          |  
|                                             |  |              |            |   |      |   |            |  

The Company has maintained a full valuation allowance against its deferred tax assets in all periods
presented. A valuation allowance is required to be recorded when it is more likely than not that some portion or all of the net deferred tax assets will not be realized. Since the Company cannot be assured of generating taxable income and thereby
realizing the net deferred tax assets, a full valuation allowance has been provided. In the years ended December 31, 2010 and 2009, the valuation allowance increased by $1,569,000 and $1,044,000, respectively.

The Company has no uncertain tax positions at December 31, 2010 and 2009 that would affect its effective tax rate. The Company does
not anticipate a significant change in the amount of uncertain tax positions over the next twelve months. Since the Company is in a loss carryforward position, the Company is generally subject to US federal and state income tax examinations by tax
authorities for all years for which a loss carryforward is available.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | INCOME TAXES (concluded)
| | ------------------------



Income tax benefits computed using the federal statutory income tax rate differs from
the Companys effective tax rate primarily due to the following:



|                                                  |  |              |        |  |      |  |        | 
|------------------------------------------------- |  | ------------ | ------ |  | ---- |  | ------ | 
|                                                  |  | December 31, |       
|                                                  |  | 2010         |        |  | 2009 | 
|Statutory tax rate                                |  |              | 34.0%  |  |      |  | 34.0%  | 
|State taxes, net of federal benefit               |  |              | 2.7%   |  |      |  | 6.2%   | 
|Permanent differences (derivative loss and other) |  |              | -19.3% |  |      |  | 0.2%   | 
|R&D tax credit                                    |  |              | 0.7%   |  |      |  | 1.6%   | 
|Increase in valuation reserve                     |  |              | -18.1% |  |      |  | -41.6% | 
|                                                  |  |              |        |  |      |  |        | 
|Effective tax rate                                |  |              | 0%     |  |      |  | 0%     | 
|                                                  |  |              |        |  |      |  |        | 



|11. | COMMON STOCK
|--- | ------------

The Company
has authorized 100,000,000 shares of Common Stock, $0.00001 par value per share, of which 51,647,171 shares and 26,259,515 shares were issued and outstanding as of December 31, 2010 and 2009, respectively.

At inception in 2005, the Company issued its founders 24,787,080 shares of Common Stock with a par value of $248 for no consideration.

In 2009, the Company issued 1,472,435 shares of Common Stock to the holders of Convertible Notes Payable upon conversion of
these notes. At the conversion dates, the principal balance of $1,141,000 and accrued interest payable of $203,366 were converted into Common Stock at a price of $0.91 per share.

In March 2010, the Company sold 1,095,258 shares of Common Stock to an investor at a price per share of $0.91 and the Company received
cash proceeds of $1,000,000.

During the six months ended June 30, 2010, the Company issued 3,792,417 shares of Common
Stock to the holders of Convertible Notes Payable upon the conversion of these notes. At the conversion date, the principal balance of $3,040,000 and accrued interest payable of $288,128 were converted into Common Stock. Certain notes provided for
conversion at a discount to the $0.91 price (see Note 8).

On October 26, 2010, in conjunction with the Merger (see Note
1), the Company issued 6,999,981 shares of Common Stock to the former shareholders of ITHC.

In connection with
the Merger on October 26, 2010 and in two subsequent closings in November and December 2010, the Company completed a private placement of 13,000,000 Units of its securities for total gross proceeds of $13,000,000 and net proceeds of
$10,927,883 (the Offering). Included in these amounts are 504,597 Units and $504,597 related to the conversion of the Bridge Notes (see Note 9). Each Unit consisted of one share of Common Stock and a warrant to purchase one share of
Common Stock exercisable at $1.40 per share (the Investor Warrants). In conjunction with the Merger and the Offering, the Company issued to an attorney 500,000 shares of its Common Stock with a fair value of $500,000. This was considered
a stock issuance cost and was therefore recorded as both a debit and credit to additional paid-in capital.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | COMMON STOCK (continued)
| | ------------------------



In order to account for the Units, the Company allocated the proceeds between the Common
Stock and warrants first to the fair value of the warrants with the residual allocated to the Common Stock. As a result, the Company allocated $4,475,791 to the warrants with the remainder of the proceeds allocated to the Common Stock. The fair
value of the Placement Agent warrants, $2,040,091, was recorded as a warrant derivative liability and a stock issuance cost net against the gross proceeds received.

In October 2010, the Company issued 500,000 shares of Common Stock with a fair value of approximately $500,000 for legal services related to the Merger and related transactions. These shares were
considered non-cash stock issuance costs and were recorded as a debit and credit to additional paid-in capital.

In connection
with the Offering, the Company paid the Placement Agent a commission of 10% of the funds raised from such investors in the Offering. In addition, the Placement Agent received a non-accountable expense allowance equal to 3% of the proceeds raised in
the Offering as well as warrants to purchase a number of shares of Common Stock equal to 20% of the number of common shares underlying Units sold to investors in the Offering. As a result of the foregoing arrangement, the Placement Agent was paid
commissions and expenses of $1,690,000 and was issued warrants to purchase (i) 2,600,000 shares of Common Stock at an exercise price of $1.00 per share and (ii) 2,600,000 shares of Common Stock at an exercise price of $1.40 per share.
Other cash expenses related to the private placement totaled $382,117.

Registration Rights Agreement

In connection with the Offering, the Company entered into a Registration Rights Agreement with the private placement
investors, whereby the Company agreed to register common stock as defined in the agreement. The Company is required to file within 90 days of the date of the final closing (the Filing Deadline), a registration statement registering for
resale all shares of Common Stock issued in the private placement, including Common Stock (i) included in the Units; and (ii) issuable upon exercise of the Investor Warrants. The Company has agreed to use its reasonable efforts to have the
registration statement declared effective within 180 days of filing the registration statement (the Effectiveness Deadline). If the Registration Statement is not filed on or before the Filing Deadline or not declared effective on or
before the Effectiveness Deadline, the Company shall pay to each holder of registrable securities an amount in cash equal to one-half of one percent (0.5%) of such holders investment in the Offering or in the Bridge Financing on every thirty
(30) day anniversary of such Filing Deadline or Effectiveness Deadline failure until such failure is cured. The payment amount shall be prorated for partial thirty (30) day periods. The maximum aggregate amount of payments to be made by
the Company as the result of such failures, whether by reason of a Filing Deadline failure, Effectiveness Deadline failure or any combination thereof, shall be an amount equal to 9% of each Unit holders investment amount. The Company shall
keep the Registration Statement effective for one (1) year from the date it is declared effective by the SEC or until Rule 144 of the Securities Act is available to the investors with respect to all of their shares, whichever is earlier.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | COMMON STOCK (concluded)
| | ------------------------



Common Stock Reserves

As of December 31, 2010, the Company had the following reserves established for the future issuance of Common Stock as follows:



|                                          |  |  |            | 
|----------------------------------------- |  |  | ---------- | 
|Reserve for the exercise of warrants      |  |  | 18,800,000 | 
|Reserve for the exercise of stock options |  |  | 9,415,557  | 
|                                          |  |  |            | 
|Total Reserves                            |  |  | 28,215,557 | 
|                                          |  |  |            | 



|12. | DERIVATIVE INSTRUMENTS
|--- | ----------------------

Certain warrants issued to the investors in the Offering, the Bridge Note investors and the Placement Agent (see Notes 10 and 11) have
provisions that include anti-dilution protection and, under certain conditions, grant the right to the holder to request the Company to repurchase the warrant. Accordingly, these warrants are accounted for as derivative liabilities. The Company uses
the Black-Scholes option pricing model and assumptions that consider among other factors the fair value of the underlying stock, risk-free interest rate, volatility, expected life and dividend rates in estimating fair value for the warrants
considered to be derivative instruments. The fair value of these derivative instruments at December 31, 2010 was $10,647,190 and is included as a derivative warrant liability, a current liability. Changes in fair value of the derivative
financial instruments are recognized currently in the Statement of Operations as a derivatives gain or loss. The warrant derivative loss for the year ended December 31, 2010 was $3,952,582 and was included in other income (expense) in the
consolidated statement of operations. There was no derivatives loss for the year ended December 31, 2009.

The
assumptions used principally in determining the fair value of warrants were as follows:



|                        |  |              |                 | 
|----------------------- |  | ------------ | --------------- | 
|                        |  | December 31, |                
|                        |  | 2010         |                
|                        | 
|Risk-free interest rate |  |              | 2.0%            | 
|Expected dividend yield |  |              | 0%              | 
|Contractual Term        |  |              | 4.7 - 4.9 years | 
|Expected volatility     |  |              | 50%             | 

The primary underlying risk exposure pertaining to the warrants is the change in fair value of the
underlying Common Stock for each reporting period.



|13. | STOCK OPTIONS
|--- | -------------

In 2007,
the Company adopted the 2007 Employee, Director and Consultant Stock Plan (the 2007 Plan). Pursuant to the 2007 Plan, the Companys Board of Directors (or committees and/or executive officers delegated by the Board of Directors) may
grant incentive and nonqualified stock options to the Companys employees, officers, directors, consultants and advisors. As of December 31, 2010, there were options to purchase an aggregate of 5,915,557 shares of Common Stock outstanding
under the 2007 Plan and no shares available for future grants under the 2007 Plan.

On October 25, 2010, the
Companys Board of Directors adopted the 2010 Equity Incentive Plan, subject to shareholder approval (the 2010 Plan). The 2010 Plan provides for grants of incentive stock options to



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Concluded)



| | STOCK OPTIONS (continued)
| | -------------------------



employees and nonqualified stock options and restricted Common Stock to employees, consultants and non-employee directors of the Company. As of December 31, 2010, the number of shares
authorized for issuance under the 2010 Plan was 3,500,000 shares. As of December 31, 2010, there were options to purchase an aggregate of 280,000 shares of Common Stock outstanding under the 2010 Plan and 3,220,000 shares available for future
grants under the 2010 Plan. If shareholder approval is not obtained by October 25, 2011, all awards granted under the 2010 Plan will terminate. In addition, no award under the 2010 Plan will become exercisable until shareholder approval has been
obtained and a registration statement on Form S-8 has been filed with the SEC.

Options issued under the 2007 Plan and the
2010 Plan, (collectively the Plans) are exercisable for up to 10 years from the date of issuance.

Share-based compensation

For stock options issued and outstanding during the years ended December 31, 2010 and 2009, the Company recorded non-cash, stock-based compensation expense of $664,908 and $171,059,
respectively, each net of estimated forfeitures.

The fair value of each option award is estimated on the date of grant using
the Black-Scholes option pricing model that uses the assumptions noted in the following table. Due to its limited operating history and limited number of sales of its Common Stock, the Company estimated its volatility in consideration of a number of
factors including the volatility of comparable public companies. The Company uses historical data, as well as subsequent events occurring prior to the issuance of the financial statements, to estimate option exercises and employee terminations
within the valuation model. The expected term of options granted under the Companys stock plans, all of which qualify as plain vanilla, is based on the average of the contractual term (generally 10 years) and the vesting
period (generally 48 months). For non-employee options, the expected term is the contractual term. The risk-free rate is based on the yield of a U.S. Treasury security with a term consistent with the option.

A summary of option activity under the Companys stock plans and options granted to officers of the Company outside any plan as of
December 31, 2010 and 2009 and changes during the years then ended is presented below:



|                                 |  |        |           |   |                              |   |      |                                                 |  |  |                          |  |  |   |            | 
|-------------------------------- |  | ------ | --------- | - | ---------------------------- | - | ---- | ----------------------------------------------- |  |  | ------------------------ |  |  | - | ---------- | 
|Options                          |  | Shares |           |   | WeightedAverageExercisePrice |   |      | WeightedAverageRemainingContractualTerm inYears |  |  | AggregateIntrinsic Value | 
|                                 |  |        |           |  
|Outstanding at December 31, 2008 |  |        | 2,980,729 |   |                              | $ | 0.07 |                                                 |  |  |                          |  |  |   |            | 
|                                 |  |        |           |  
|Granted                          |  |        | 963,941   |   |                              | $ | 0.86 |                                                 |  |  |                          |  |  |   |            | 
|Forfeited                        |  |        | (82,624   | ) |                              | $ | 0.07 |                                                 |  |  |                          |  |  |   |            | 
|                                 |  |        |           |   |                              |   |      |                                                 |  |  |                          |  |  |   |            | 
|Outstanding at December 31, 2009 |  |        | 3,862,046 |   |                              | $ | 0.27 |                                                 |  |  |                          |  |  |   |            | 
|                                 |  |        |           |  
|Granted                          |  |        | 2,333,511 |   |                              | $ | 1.13 |                                                 |  |  |                          |  |  |   |            | 
|                                 |  |        |           |   |                              |   |      |                                                 |  |  |                          |  |  |   |            | 
|                                 |  |        |           |  
|Outstanding at December 31, 2010 |  |        | 6,195,557 |   |                              | $ | 0.59 |                                                 |  |  | 8.31                     |  |  | $ | 10,322,073 | 
|                                 |  |        |           |   |                              |   |      |                                                 |  |  |                          |  |  |   |            | 
|                                 |  |        |           |  
|Vested at December 31, 2010      |  |        | 2,406,112 |   |                              | $ | 0.15 |                                                 |  |  | 7.04                     |  |  | $ | 5,072,223  | 
|                                 |  |        |           |   |                              |   |      |                                                 |  |  |                          |  |  |   |            | 



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | STOCK OPTIONS (concluded)
| | -------------------------



The weighted average grant-date fair value of options granted during the years ended
December 31, 2010 and 2009 was $0.55 and $0.45 per share, respectively. The total fair value of options that vested in the years ended December 31, 2010 and 2009 was $962,810 and $346,976, respectively. As of December 31, 2010 and
2009, there was approximately $2,236,133 and $1,026,595 of total unrecognized compensation expense, respectively, related to non-vested share-based option compensation arrangements. The unrecognized compensation expense is estimated to be recognized
over a period of 2.95 and 2.72 years at December 31, 2010 and 2009, respectively.



|14. | WARRANTS
|--- | --------

The following
presents information about warrants to purchase Common Stock issued and outstanding at December 31, 2010:



|                                |  |                   |            |      |               |   |      |                    |  |  |                        | 
|------------------------------- |  | ----------------- | ---------- | ---- | ------------- | - | ---- | ------------------ |  |  | ---------------------- | 
|Year Issued                     |  | Number ofWarrants |            |      | ExercisePrice |   |      | Date of Expiration | 
|2010                            |  |                   | 15,600,000 |      |               | $ | 1.40 |                    |  |  | 10/26/2015 - 12/3/2015 | 
|2010                            |  |                   | 3,200,000  |      |               |   | 1.00 |                    |  |  | 9/26/2015 - 12/3/2015  | 
|                                |  |                   |            |      |               |   |      |                    |  |  |                        | 
|Total                           |  |                   | 18,800,000 |      |               |   |      |                    |  |  |                        | 
|                                |  |                   |            |      |               |   |      |                    |  |  |                        | 
|Weighted average exercise price |  |                   | $          | 1.33 |               |   |      |                    | 
|                                |  |                   |            |      |               |   |      |                    |  |  |                        | 
|Weighted average life in years  |  |                   |            |      |               |   |      | 4.8                | 
|                                |  |                   |            |      |               |   |      |                    |  |  |                        | 



|15. | EMPLOYEE BENEFIT PLAN
|--- | ---------------------

In
November 2006, the Company adopted a 401(k) plan (the Plan) covering all employees. Employees must be 21 years of age in order to participate in the Plan. Under the Plan, the Company has the option to make matching contributions but has
elected not to do so.



|16. | INTELLECTUAL PROPERTY LICENSE
|--- | -----------------------------

The Company has obtained a world-wide exclusive license (the CMCC License) for patents co-owned by Massachusetts Institute of Technology and Harvards Childrens Hospital covering
the use of biopolymers to treat spinal cord injuries, and to promote the survival and proliferation of human stem cells in the spinal cord. The CMCC License has a 15-year term, or as long as the life of the last expiring patent right, whichever is
longer, unless terminated earlier by the licensor. In connection with the CMCC License, the Company paid an initial $75,000 licensing fee (see Note 3) and is required to pay certain annual maintenance fees, milestone payments and
royalties. All costs associated with maintenance of the CMCC License are expensed as incurred.



|17. | COMMITMENTS AND CONTINGENCIES
|--- | -----------------------------

Legal Settlement

In 2009, the Company filed a lawsuit against a
party alleging damages from a breach of a contract under which the party was providing services to the Company. In exchange for a payment of $383,000 from the party, the Company agreed to dismiss the lawsuit. The $383,000 received was recorded as
other income in the Statement of Operations in the year ended December 31, 2009.



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Continued)



| | COMMITMENTS AND CONTINGENCIES (concluded)
| | -----------------------------------------



Operating Lease

On November 15, 2010, the Company entered into a commercial lease for 1,200 square feet of office and laboratory space in Medford, MA. The
term of this lease is for two years with monthly payments of approximately $3,900.

Pursuant to the terms of the
non-cancelable lease agreement in effect at December 31, 2010, future minimum rent commitments are as follows:



|                        |  |        
|----------------------- |  | -------
|Year Ended December 31, |  |        
|2011                    |  | $47,061
|2012                    |  | 43,139 
|                        |  |        
|Total                   |  | $90,200
|                        |  |        

Total rent expense for the years ended December 31, 2010 and 2009, including month-to-month leases, was
approximately $270,000 and $123,000.



|18. | RESTATEMENT
|--- | -----------

The Company
is restating its 2010 financial statements to correct an error related to the accounting for derivative liabilities. The error related to the process of allocating the proceeds of a financing to two instruments when one of those instruments was a
derivative liability. Originally, the Company allocated the proceeds using the relative fair value of the two instruments with the derivative liability being recorded at its fair value and any difference between the relative fair value and fair
value being charged to a derivative gain or loss upon issuance. Although Generally Accepted Accounting Principles (GAAP) does not address this situation specifically and the Company believed its original accounting to be supported by
GAAP, after discussions with the SEC Staff the Company determined that its accounting was not consistent with common practice used by other registrants in similar circumstances.

The December 31, 2010 balance sheet line items were impacted by the following amounts:



|                                                 |  |   |            |  
|------------------------------------------------ |  | - | ---------- | -
|Additional paid-in capital                       |  | $ | (1,146,312 | )
|Deficit accumulated during the development stage |  |   | 1,146,312  |  

The statement of operations line items were impacted as follows:



|                                            |  |                             |           |  |                                                              |   |           | 
|------------------------------------------- |  | --------------------------- | --------- |  | ------------------------------------------------------------ | - | --------- | 
|                                            |  | Year EndedDecember 31, 2010 |           |  | Period from November 28,2005 (inception) toDecember 31, 2010 |  
|Derivatives losses                          |  | $                           | 1,146,312 |  |                                                              | $ | 1,146,312 | 
|Net loss                                    |  | $                           | 1,146,312 |  |                                                              | $ | 1,146,312 | 
|Net loss per share, basic and fully diluted |  | $                           | 0.03      |  |                                                              | $ | 0.05      | 



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##### Table of Contents

InVivo Therapeutics Holdings Corp.

(A Development Stage Company)

Notes to Consolidated Financial Statements (Concluded)



| | RESTATEMENT (concluded)
| | -----------------------



The statement of changes in stockholders equity for the year ended December 31,
2010 line items were impacted as follows:



|                                                                                                                                         |  |   |            |  
|---------------------------------------------------------------------------------------------------------------------------------------- |  | - | ---------- | -
|Issuance of common stock in private placement, net of stock issuance costs of $2,072,117 and non-cash stock issuance costs of
$5,369,570 |  | $ | (1,146,312 | )
|Net loss                                                                                                                                 |  |   | 1,146,312  |  



|19. | SUBSEQUENT EVENT
|--- | ----------------

Subsequent to December 31, 2010, the Company issued 27,541 shares of Common Stock upon exercise of stock options.



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##### Table of Contents

PART IV



|Item 15. | EXHIBITS, FINANCIAL STATEMENT SCHEDULES
|-------- | ---------------------------------------

(a) Documents filed as part of this Annual Report.

(3) Exhibits:



|          |  |                                                                                                                                            
|--------- |  | -------------------------------------------------------------------------------------------------------------------------------------------
|31.1/31.2 |  | Certification by the Principal Executive Officer and Principal Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
|          | 
|32.1/32.2 |  | Certification of Principal Executive Officer and Principal Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.    



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##### Table of Contents

SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly
authorized.



|                    |  |                                    |  |                                                                                                                   
|------------------- |  | ---------------------------------- |  | ------------------------------------------------------------------------------------------------------------------
|                    |  | INVIVO THERAPEUTICS HOLDINGS CORP.
|                    |  |                                   
|Date: June 30, 2011 |  | By:                                |  | /s/ Frank M. Reynolds                                                                                             
|                    |  |                                    |  | Name: Frank M. Reynolds                                                                                           
|                    |  |                                    |  | Title: Chief Executive Officer and Chief Financial Officer (Principal Executive, Financial and Accounting Officer)

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following
persons on behalf of the registrant and in the capacities and on the dates indicated.



|                                          |  |                                                                                                                       |  |              
|----------------------------------------- |  | --------------------------------------------------------------------------------------------------------------------- |  | -------------
|Signature                                 |  | Title                                                                                                                 |  | Date         
|                                          |  |                                                                                                                      
|/s/ Frank M. Reynolds Frank M. Reynolds   |  | Chairman, Chief Executive Officer and Chief Financial Officer (Principal Executive, Financial and Accounting Officer) |  | June 30, 2011
|                                          | 
|                                          |  |                                                                                                                      
|George Nolen                              |  | Director                                                                                                              |  |              
|                                          |  |                                                                                                                      
|Christi M. Pedra                          |  | Director                                                                                                              |  |              
|                                          |  |                                                                                                                      
|/s/ Richard J. Roberts Richard J. Roberts |  | Director                                                                                                              |  | June 29, 2011
|                                          |  |                                                                                                                      
|/s/ Adam K. Stern Adam K. Stern           |  | Director                                                                                                              |  | June 30, 2011



31