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Exhibit
12.1

302 CERTIFICATION

CERTIFICATION OF CHIEF
EXECUTIVE OFFICER

I, Doron Gerstel, certify
that:

1. I have reviewed this annual
report on Form 20-F of Syneron Medical Ltd.;

2. Based on my knowledge,  this
report does not contain any untrue  statement of a material fact or omit to state a
material fact  necessary to make the statements  made, in light of the  circumstances
 under which such  statements were made, not misleading with respect to the period
covered by this report;

3. Based on my knowledge,  the
 financial  statements,  and other  financial  information  included in this report,
fairly  present in all material  respects the  financial  condition,  results of
 operations  and cash flows of the company as of, and for, the periods presented in this
report;

4. The registrant's other certifying
 officer(s) and I are responsible for establishing and maintaining  disclosure controls
and  procedures  (as defined in Exchange  Act Rules  13a-15(e)  and  15d-15(e)  and
internal  control over financial reporting (as defined in Exchange Act Rules13a-15(f) and
15d-15(f)) for the company and have:

|a. | designed
such disclosure  controls and procedures,  or caused such disclosure  controls and
procedures to be        designed under our supervision,  to ensure that material
information relating to the company,  including its        consolidated  subsidiaries,
 is made known to us by others within those  entities,  particularly  during the
       period in which this report is being prepared;
|-- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|b. | designed
such internal  control over  financial  reporting,  or caused such internal  control over
financial        reporting to be designed under our supervision,  to provide reasonable
 assurance  regarding the reliability        of financial  reporting and the  preparation
 of financial  statements  for external  purposes in accordance        with generally
accepted accounting principles;
|-- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|c. | evaluated
 the  effectiveness  of the company's  disclosure  controls and  procedures  and
presented in this        report our conclusions about the effectiveness of the disclosure
 controls and procedures,  as of the end of        the period covered by this report
based on such evaluation; and
|-- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|d. | disclosed
 in this  report any change in the  company's  internal  control  over  financial
 reporting  that        occurred  during the period  covered by the annual  report that
has  materially  affected,  or is reasonably        likely to materially affect, the
company's internal control over financial reporting; and
|-- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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5. The  company's  other  certifying
 officer(s)  and I have  disclosed,  based on our most  recent  evaluation  of internal
 control over financial  reporting,  to the company's  auditors and the audit committee
of company's board of directors (or persons performing the equivalent function):

|a. | all
  significant   deficiencies   and  material   weaknesses   in  the  design  or
 operation  of  internal        control over financial  reporting which are reasonably
 likely to adversely affect the company's  ability to        record, process, summarize
and report financial data; and
|-- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|b. | any
fraud,  whether or not  material,  that involves  management  or other  employees who
have a significant        role in the company's internal control over financial reporting.
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Date: June 15, 2007

|/s/ Doron Gerstel
Doron GerstelChief Executive Officer |  | 
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