EXHIBIT 31.1

                                  CERTIFICATION

I, Matthew L. Schissler, certify that:

1.   I have reviewed this annual report on Form 10-KSB of Cord Blood America,
     Inc.;

2.   Based on my knowledge, this report does not contain any untrue statement of
     a material fact or omit to state a material fact necessary to make the
     statements made, in light of the circumstances under which such statements
     were made, not misleading with respect to the period covered by this
     report;

3.   Based on my knowledge, the financial statements, and other financial
     information included in this report, fairly present in all material
     respects the financial condition, results of operations and cash flows of
     Cord Blood America, Inc. as of, and for, the periods presented in this
     report;

4.   I am responsible for establishing and maintaining disclosure controls and
     procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for
     Cord Blood America, Inc. and have:

     A.   Designed such disclosure controls and procedures to ensure that
          material information relating to Cord Blood America, Inc., including
          its consolidated subsidiaries, is made known to me by others within
          those entities, particularly during the period in which this report is
          being prepared;

     B.   Designed such internal control over financial reporting, or caused
          such internal control over financial reporting to be designed under
          our supervision, to provide reasonable assurance regarding the
          reliability of financial reporting and the preparation of financial
          statements for external purposes in accordance with generally accepted
          accounting principles;

     C.   Evaluated the effectiveness of Cord Blood America, Inc.'s disclosure
          controls and procedures and presented in this report our conclusions
          about the effectiveness of the disclosure controls and procedures, as
          of the end of the period covered by this report based on such
          evaluation; and

     D.   Disclosed in this report any change in Cord Blood America, Inc.'s
          internal controls over financial reporting that occurred during Cord
          Blood America, Inc.'s most. recent fiscal quarter (Cord Blood America,
          Inc.'s fourth fiscal quarter in the case of an annual report) that has
          materially affected or is reasonably likely to materially affect, Cord
          Blood America, Inc.'s internal control over financial reporting.

5.   I have disclosed, based on my most recent evaluation of internal control
     over financial reporting, to Cord Blood America, Inc.'s auditors and the
     Cord Blood America, Inc.'s board of directors:

     A.   All significant deficiencies and material weaknesses in the design or
          operation of internal control over financial reporting which are
          reasonably likely to adversely affect Cord Blood America, Inc.'s
          ability to record, process, summarize and report financial
          information; and

     B.   Any fraud, whether or not material, that involves management or other
          employees who have a significant role in Cord Blood America, Inc.'s
          internal control over financial reporting.

Dated: April 15, 2008


                               /s/ Matthew L. Schissler
                               -------------------------------------------------
                               Matthew L. Schissler
                               Chairman of the Board and Chief Executive Officer