# Patent

## Title
Neisseria meningitidis antigens and compositions

## Abstract

The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.

## Background
RELATED APPLICATIONS
This application is a Continuation of U.S. patent application Ser. No. 13/359,442, filed Jan. 26, 2012, now pending, which is a Continuation of U.S. patent application Ser. No. 13/070,448, filed Mar. 23, 2011, now pending, which is a Divisional of U.S. patent application Ser. No. 12/013,047, filed Jan. 11, 2008, now U.S. Pat. No. 7,988,979, which is continuation of U.S. patent application Ser. No. 09/674,546, filed Nov. 4, 2002, now U.S. Pat. No. 7,576,176, which is the National Stage of International Application No. PCT/US99/09346, filed Apr. 30, 1999, which claims the benefit under 35 U.S.C. §119(e) of U.S. Provisional Patent Nos. 60/121,528, filed Feb. 25, 1999, 60/103,796, filed Oct. 9, 1998, 60/103,794, filed Oct. 9, 1998, 60/103,749, filed Oct. 9, 1998, 60/099,062, filed Sep. 2, 1998, 60/098,994, filed Sep. 2, 1998, 60/094,869, filed Jul. 31, 1998, and 60/083,758, filed May 1, 1998. Each of the foregoing patent applications is incorporated by reference in their entirety.


SUBMISSION OF SEQUENCE LISTING ON ASCII TEXT FILE
The content of the following submission on ASCII text file is incorporated herein by reference in its entirety: a computer readable form (CRF) of the Sequence Listing (file name: 529552002003SubSeqList.txt, date recorded: Nov. 18, 2014, size: 6,322 KB).
FIELD OF THE INVENTION
This invention relates to antigens from the bacterial species: Neisseria meningitidis and Neisseria gonorrhoeae. 
BACKGROUND
Neisseria meningitidis is a non-motile, gram negative diplococcus human pathogen. It colonizes the pharynx, causing meningitis and, occasionally, septicaemia in the absence of meningitis. It is closely related to N. gonorrhoea, although one feature that clearly differentiates meningococcus from gonococcus is the presence of a polysaccharide capsule that is present in all pathogenic meningococci.
N. meningitidis causes both endemic and epidemic disease. In the United States the attack rate is 0.6-1 per 100,000 persons per year, and it can be much greater during outbreaks. (see Lieberman et al. (1996) Safety and Immunogenicity of a Serogroups A/C Neisseria meningitidis Oligosaccharide-Protein Conjugate Vaccine in Young Children. JAMA 275(19):1499-1503; Schuchat et al (1997) Bacterial Meningitis in the United States in 1995. N Engl J Med 337(14):970-976). In developing countries, endemic disease rates are much higher and during epidemics incidence rates can reach 500 cases per 100,000 persons per year. Mortality is extremely high, at 10-20% in the United States, and much higher in developing countries. Following the introduction of the conjugate vaccine against Haemophilus influenzae, N. meningitidis is the major cause of bacterial meningitis at all ages in the United States (Schuchat et al (1997) supra).
Based on the organism's capsular polysaccharide, 12 serogroups of N. meningitidis have been identified. Group A is the pathogen most often implicated in epidemic disease in sub-Saharan Africa. Serogroups B and C are responsible for the vast majority of cases in the United States and in most developed countries. Serogroups W135 and Y are responsible for the rest of the cases in the United States and developed countries. The meningococcal vaccine currently in use is a tetravalent polysaccharide vaccine composed of serogroups A, C, Y and W135. Although efficacious in adolescents and adults, it induces a poor immune response and short duration of protection, and cannot be used in infants [eg. Morbidity and Mortality weekly report, Vol. 46, No. RR-5 (1997)]. This is because polysaccharides are T-cell independent antigens that induce a weak immune response that cannot be boosted by repeated immunization. Following the success of the vaccination against H. influenzae, conjugate vaccines against serogroups A and C have been developed and are at the final stage of clinical testing (Zollinger W D “New and Improved Vaccines Against Meningococcal Disease”. In: New Generation Vaccines, supra, pp. 469-488; Lieberman et al (1996) supra; Costantino et al (1992) Development and phase I clinical testing of a conjugate vaccine against meningococcus A and C. Vaccine 10:691-698).
Meningococcus B (menB) remains a problem, however. This serotype currently is responsible for approximately 50% of total meningitis in the United States, Europe, and South America. The polysaccharide approach cannot be used because the menB capsular polysaccharide is a polymer of α(2-8)-linked N-acetyl neuraminic acid that is also present in mammalian tissue. This results in tolerance to the antigen; indeed, if an immune response were elicited, it would be anti-self, and therefore undesirable. In order to avoid induction of autoimmunity and to induce a protective immune response, the capsular polysaccharide has, for instance, been chemically modified substituting the N-acetyl groups with N-propionyl groups, leaving the specific antigenicity unaltered (Romero & Outschoorn (1994) Current status of Meningococcal group B vaccine candidates: capsular or non-capsular? Clin Microbiol Rev 7(4):559-575).
Alternative approaches to menB vaccines have used complex mixtures of outer membrane proteins (OMPs), containing either the OMPs alone, or OMPs enriched in porins, or deleted of the class 4 OMPs that are believed to induce antibodies that block bactericidal activity. This approach produces vaccines that are not well characterized. They are able to protect against the homologous strain, but are not effective at large where there are many antigenic variants of the outer membrane proteins. To overcome the antigenic variability, multivalent vaccines containing up to nine different porins have been constructed (eg. Poolman J T (1992) Development of a meningococcal vaccine. Infect. Agents Dis. 4:13-28). Additional proteins to be used in outer membrane vaccines have been the opa and opc proteins, but none of these approaches have been able to overcome the antigenic variability (eg. Ala'Aldeen & Borriello (1996) The meningococcal transferrin-binding proteins 1 and 2 are both surface exposed and generate bactericidal antibodies capable of killing homologous and heterologous strains. Vaccine 14(1):49-53).
A certain amount of sequence data is available for meningococcal and gonoccocal genes and proteins (eg. EP-A-0467714, WO96/29412), but this is by no means complete. The provision of further sequences could provide an opportunity to identify secreted or surface-exposed proteins that are presumed targets for the immune system and which are not antigenically variable. For instance, some of the identified proteins could be components of efficacious vaccines against meningococcus B, some could be components of vaccines against all meningococcal serotypes, and others could be components of vaccines against all pathogenic Neisseriae including Neisseria meningitidis or Neisseria gonorrhoeae. Those sequences specific to N. meningitidis or N. gonorrhoeae that are more highly conserved are further preferred sequences.
It is thus an object of the invention is to provide Neisserial DNA sequences which encode proteins that are antigenic or immunogenic.



BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 illustrates the products of (B) protein expression and (A) purification, (C) FACs analysis, (D) bactericidal assay, (E) western blot, and (F) ELISA assay of the predicted ORF 919 as cloned and expressed in E. coli. 
FIG. 2 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 279 as cloned and expressed in E. coli. 
FIG. 3 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 576-1 as cloned and expressed in E. coli. 
FIG. 4 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 519-1 as cloned and expressed in E. coli. 
FIG. 5 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 121-1 as cloned and expressed in E. coli. 
FIG. 6 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 128-1 as cloned and expressed in E. coli. 
FIG. 7 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 206 as cloned and expressed in E. coli. 
FIG. 8 illustrates the products of (A) protein expression and purification, (B) FACs analysis, (C) bactericidal assay, and (D) ELISA assay of the predicted ORF 287 as cloned and expressed in E. coli. 
FIG. 9 illustrates the products of (A) protein expression and purification, (B) western blot, (C) FACs analysis, (D) bactericidal assay, and (E) ELISA assay of the predicted ORF 406 as cloned and expressed in E. coli. 
FIG. 10 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 919 as cloned and expressed in E. coli. 
FIG. 11 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 279 as cloned and expressed in E. coli. 
FIG. 12 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 576-1 as cloned and expressed in E. coli. 
FIG. 13 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 519-1 as cloned and expressed in E. coli. 
FIG. 14 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 121-1 as cloned and expressed in E. coli. 
FIG. 15 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 128-1 as cloned and expressed in E. coli. 
FIG. 16 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 206 as cloned and expressed in E. coli. 
FIG. 17 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 287 as cloned and expressed in E. coli. 
FIG. 18 illustrates the hydrophilicity plot, antigenic index and AMPHI regions of the products of protein expression the predicted ORF 406 as cloned and expressed in E. coli. 
FIG. 19A-C shows an alignment comparison of amino acid sequences for ORF 225 for several strains of Neisseria. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. The Figure demonstrates a high degree of conservation among the various strains, further confirming its utility as an antigen for both vaccines and diagnostics. The sequences in the Figure have the following SEQ ID NOs: FA1090 SEQ ID 3115; Z2491 SEQ ID 3116; ZO01—225 SEQ ID 3117; ZO02—225 SEQ ID 3118; ZO03_SEQ ID 3119; ZO04—225 SEQ ID 3120; ZO05—225 SEQ ID 3121; ZO06—225 SEQ ID 3122; ZO07—225 SEQ ID 3123; ZO08—225 SEQ ID 3124; ZO09—225 SEQ ID 3125; ZO10—225 SEQ ID 3126; ZO11—225 SEQ ID 3127; ZO12—225 SEQ ID 3128; ZO13—225 SEQ ID 3129; ZO14—225 SEQ ID 3130; ZO15—225 <SEQ ID 3131; ZO16—225 SEQ ID 3132; ZO17—225 SEQ ID 3133; ZO18—225 SEQ ID 3134; ZO19—225 SEQ ID 3135; ZO20—225 SEQ ID 3136; ZO21—225 SEQ ID 3137; ZO22—225 SEQ ID 3138; ZO23—225 SEQ ID 3139; ZO24—225 SEQ ID 3140; ZO25—225 SEQ ID 3141; ZO26—225 SEQ ID 3142; ZO27—225 SEQ ID 3143; ZO28—225 SEQ ID 3144; ZO29—225 SEQ ID 3145; ZO32—225 SEQ ID 3146; ZO33—225 SEQ ID 3147; and ZO96—225 SEQ ID 3148.
FIG. 20A-B shows an alignment comparison of amino acid sequences for ORF 235 for several strains of Neisseria. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. The Figure demonstrates a high degree of conservation among the various strains, further confirming its utility as an antigen for both vaccines and diagnostics. The sequences in the Figure have the following SEQ ID NOs: FA1090 SEQ ID 3149; GNMZQ01 SEQ ID 3150; GNMZQ02 SEQ ID 3151; GNMZQ03 SEQ ID 31521; GNMZQ04 SEQ ID 3153; GNMZQ05 SEQ ID 3154; GNMZQ07 SEQ ID 3155; GNMZQ08 SEQ ID 3156; GNMZQ09 SEQ ID 3157; GNMZQ10 SEQ ID 3158; GNMZQ11 SEQ ID 3159; GNMZQ13 SEQ ID 3160; GNMZQ14 SEQ ID 3161; GNMZQ15 SEQ ID 3162; GNMZQ16 SEQ ID 3163; GNMZQ17 SEQ ID 3164; GNMZQ18 SEQ ID 3165; GNMZQ19 SEQ ID 3166; GNMZQ21 SEQ ID 3166; GNMZQ22 SEQ ID 3167; GNMZQ23 SEQ ID 3168; GNMZQ24 SEQ ID 3169; GNMZQ25 SEQ ID 3170; GNMZQ26 SEQ ID 3171; GNMZQ27 SEQ ID 3172; GNMZQ28 SEQ ID 3173; GNMZQ29 SEQ ID 3174; GNMZQ31 SEQ ID 3175; GNMZQ32 SEQ ID 3176; GNMZQ33 SEQ ID 3177; and Z2491 SEQ ID 3178.
FIG. 21A-B shows an alignment comparison of amino acid sequences for ORF 287 for several strains of Neisseria. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. The Figure demonstrates a high degree of conservation among the various strains, further confirming its utility as an antigen for both vaccines and diagnostics. The sequences in the Figure have the following SEQ ID NOs: 287—14 SEQ ID 3179; 287—2 SEQ ID 3180; 287—21. SEQ ID 3181; 287—9 SEQ ID 3182; FA1090 SEQ ID 3183; and Z2491 SEQ ID 3184.
FIG. 22A-B shows an alignment comparison of amino acid sequences for ORF 519 for several strains of Neisseria. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. The Figure demonstrates a high degree of conservation among the various strains, further confirming its utility as an antigen for both vaccines and diagnostics. The sequences in the Figure have the following SEQ ID NOs: FA1090—519 SEQ ID 3185; Z2491—519 SEQ ID 3186; ZVO1—519 SEQ ID 3187; ZVO2—519 SEQ ID 3188; ZVO3—519 SEQ ID 3189; ZV04—519 SEQ ID 3190; ZV05—519 SEQ ID 3191; ZV06—519ASS SEQ ID 3192; ZV07—519 SEQ ID 3193; ZV11—519 SEQ ID 3194; ZV12—519 SEQ ID 3195; ZV18—519 SEQ ID 3196; ZV19—519 SEQ ID 3197; ZV20—519ASS SEQ ID 3198; ZV21—519ASS SEQ ID 3199; ZV22—519ASS SEQ ID 3200; ZV26—519 SEQ ID 3201; ZV27—519 SEQ ID 3202; ZV28—519 SEQ ID 3203; ZV29—519ASS SEQ ID 3204; ZV32—519 SEQ ID 3205; and ZV96—519 SEQ ID 3206.
FIG. 23A-D shows an alignment comparison of amino acid sequences for ORF 919 for several strains of Neisseria. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. The Figure demonstrates a high degree of conservation among the various strains, further confirming its utility as an antigen for both vaccines and diagnostics. The sequences in the Figure have the following SEQ ID NOs: FA1090 SEQ ID 3207; Z2491 <SEQ ID 3208; ZM01 SEQ ID 3209; ZM02 SEQ ID 3210; ZM03 SEQ ID 3211; ZM04 SEQ ID 3212; ZM05 SEQ ID 3213; ZM06 SEQ ID 3214; ZM07 SEQ ID 3215; ZM08N SEQ ID 3216; ZM09 SEQ ID 3217; ZM10 SEQ ID 3218; ZM11ASBC SEQ ID 3219; ZM12 SEQ ID 3220; ZM13 SEQ ID 3221; ZM14 SEQ ID 3222; ZM15 SEQ ID 3223; ZM16 SEQ ID 3224; ZM17 SEQ ID 3225; ZM18 SEQ ID 3226; ZM19 SEQ ID 3227; ZM20 SEQ ID 3228; ZM21 SEQ ID 3229; ZM22 SEQ ID 3230; ZM23ASBC SEQ ID 3231; ZM24 SEQ ID 3232; ZM25 SEQ ID 3233; ZM26 SEQ ID 3234; ZM27BC SEQ ID 3235; ZM28 SEQ ID 3236; ZM29ASBC SEQ ID 3237; ZM31ASBC SEQ ID 3238; ZM32ASBC SEQ ID 3239; ZM33ASBC SEQ ID 3240; ZM96 SEQ ID 3241.



THE INVENTION
The invention provides proteins comprising the N. meningitidis amino acid sequences and N. gonorrhoeae amino acid sequences disclosed in the examples.
It also provides proteins comprising sequences homologous (i.e., those having sequence identity) to the N. meningitidis amino acid sequences disclosed in the examples. Depending on the particular sequence, the degree of homology (sequence identity) is preferably greater than 50% (eg. 60%, 70%, 80%, 90%, 95%, 99% or more). These proteins include mutants and allelic variants of the sequences disclosed in the examples. Typically, 50% identity or more between two proteins is considered to be an indication of functional equivalence. Identity between proteins is preferably determined by the Smith-Waterman homology search algorithm as implemented in MPSRCH program (Oxford Molecular) using an affine gap search with parameters:gap penalty 12, gap extension penalty 1.
The invention further provides proteins comprising fragments of the N. meningitidis amino acid sequences and N. gonorrhoeae amino acid sequences disclosed in the examples. The fragments should comprise at least n consecutive amino acids from the sequences and, depending on the particular sequence, n is 7 or more (eg. 8, 10, 12, 14, 16, 18, 20 or more). Preferably the fragments comprise an epitope from the sequence.
The proteins of the invention can, of course, be prepared by various means (eg. recombinant expression, purification from cell culture, chemical synthesis etc.) and in various forms (eg. native, fusions etc.). They are preferably prepared in substantially pure or isolated form (ie. substantially free from other N. meningitidis or N. gonorrhoeae host cell proteins)
According to a further aspect, the invention provides antibodies which bind to these proteins. These may be polyclonal or monoclonal and may be produced by any suitable means.
According to a further aspect, the invention provides nucleic acid comprising the N. meningitidis nucleotide sequences and N. gonorrhoeae nucleotide sequences disclosed in the examples.
According to a further aspect, the invention comprises nucleic acids having sequence identity of greater than 50% (e.g., 60%, 70%, 80%, 90%, 95%, 99% or more) to the nucleic acid sequences herein. Sequence identity is determined as above-discussed.
According to a further aspect, the invention comprises nucleic acid that hybridizes to the sequences provided herein. Conditions for hybridization are set forth herein.
Nucleic acid comprising fragments of these sequences are also provided. These should comprise at least n consecutive nucleotides from the N. meningitidis sequences or N. gonorrhoeae sequences and depending on the particular sequence, n is 10 or more (eg 12, 14, 15, 18, 20, 25, 30, 35, 40 or more).
According to a further aspect, the invention provides nucleic acid encoding the proteins and protein fragments of the invention.
It should also be appreciated that the invention provides nucleic acid comprising sequences complementary to those described above (eg. for antisense or probing purposes).
Nucleic acid according to the invention can, of course, be prepared in many ways (eg. by chemical synthesis, in part or in whole, from genomic or cDNA libraries, from the organism itself etc.) and can take various forms (eg. single stranded, double stranded, vectors, probes etc.).
In addition, the term “nucleic acid” includes DNA and RNA, and also their analogues, such as those containing modified backbones, and also protein nucleic acids (PNA) etc.
According to a further aspect, the invention provides vectors comprising nucleotide sequences of the invention (eg. expression vectors) and host cells transformed with such vectors.
According to a further aspect, the invention provides compositions comprising protein, antibody, and/or nucleic acid according to the invention. These compositions may be suitable as vaccines, for instance, or as diagnostic reagents or as immunogenic compositions.
The invention also provides nucleic acid, protein, or antibody according to the invention for use as medicaments (eg. as vaccines) or as diagnostic reagents. It also provides the use of nucleic acid, protein, or antibody according to the invention in the manufacture of (I) a medicament for treating or preventing infection due to Neisserial bacteria (ii) a diagnostic reagent for detecting the presence of Neis serial bacteria or of antibodies raised against Neis serial bacteria or (iii) for raising antibodies. Said Neisserial bacteria may be any species or strain (such as N. gonorrhoeae) but are preferably N. meningitidis, especially strain B or strain C.
The invention also provides a method of treating a patient, comprising administering to the patient a therapeutically effective amount of nucleic acid, protein, and/or antibody according to the invention.
According to further aspects, the invention provides various processes.
A process for producing proteins of the invention is provided, comprising the step of culturing a host cell according to the invention under conditions which induce protein expression.
A process for detecting polynucleotides of the invention is provided, comprising the steps of: (a) contacting a nucleic probe according to the invention with a biological sample under hybridizing conditions to form duplexes; and (b) detecting said duplexes.
A process for detecting proteins of the invention is provided, comprising the steps of: (a) contacting an antibody according to the invention with a biological sample under conditions suitable for the formation of an antibody-antigen complexes; and (b) detecting said complexes.
A summary of standard techniques and procedures which may be employed in order to perform the invention (eg. to utilize the disclosed sequences for vaccination or diagnostic purposes) is attached as an Appendix to the application. This summary is not a limitation on the invention but, rather, gives examples that may be used, but are not required.
Having now generally described the invention, the same will be more readily understood through reference to the following examples which are provided by way of illustration, and are not intended to be limiting of the present invention, unless specified.
Methodology—Summary of Standard Procedures and Techniques.
General
This invention provides Neisseria meningitidis menB nucleotide sequences, amino acid sequences encoded therein. With these disclosed sequences, nucleic acid probe assays and expression cassettes and vectors can be produced. The expression vectors can be transformed into host cells to produce proteins. The purified or isolated polypeptides (which may also be chemically synthesized) can be used to produce antibodies to detect menB proteins. Also, the host cells or extracts can be utilized for biological assays to isolate agonists or antagonists. In addition, with these sequences one can search to identify open reading frames and identify amino acid sequences. The proteins may also be used in immunogenic compositions, antigenic compositions and as vaccine components.
The practice of the present invention will employ, unless otherwise indicated, conventional techniques of molecular biology, microbiology, recombinant DNA, and immunology, which are within the skill of the art. Such techniques are explained fully in the literature e.g., Sambrook Molecular Cloning; A Laboratory Manual, Second Edition (1989); DNA Cloning, Volumes I and ii (D. N Glover ed. 1985); Oligonucleotide Synthesis (M. J. Gait ed, 1984); Nucleic Acid Hybridization (B. D. Hames & S. J. Higgins eds. 1984); Transcription and Translation (B. D. Hames & S. J. Higgins eds. 1984); Animal Cell Culture (R. I. Freshney ed. 1986); Immobilized Cells and Enzymes (IRL Press, 1986); B. Perbal, A Practical Guide to Molecular Cloning (1984); the Methods in Enzymology series (Academic Press, Inc.), especially volumes 154 & 155; Gene Transfer Vectors for Mammalian Cells (J. H. Miller and M. P. Calos eds. 1987, Cold Spring Harbor Laboratory); Mayer and Walker, eds. (1987), Immunochemical Methods in Cell and Molecular Biology (Academic Press, London); Scopes, (1987) Protein Purification: Principles and Practice, Second Edition (Springer-Verlag, N.Y.), and Handbook of Experimental Immunology, Volumes I-IV (D. M. Weir and C. C. Blackwell eds 1986).
Standard abbreviations for nucleotides and amino acids are used in this specification.
All publications, patents, and patent applications cited herein are incorporated in full by reference.
Expression Systems
The Neisseria menB nucleotide sequences can be expressed in a variety of different expression systems; for example those used with mammalian cells, plant cells, baculoviruses, bacteria, and yeast.
i. Mammalian Systems
Mammalian expression systems are known in the art. A mammalian promoter is any DNA sequence capable of binding mammalian RNA polymerase and initiating the downstream (3′) transcription of a coding sequence (e.g., structural gene) into mRNA. A promoter will have a transcription initiating region, which is usually placed proximal to the 5′ end of the coding sequence, and a TATA box, usually located 25-30 base pairs (bp) upstream of the transcription initiation site. The TATA box is thought to direct RNA polymerase II to begin RNA synthesis at the correct site. A mammalian promoter will also contain an upstream promoter element, usually located within 100 to 200 bp upstream of the TATA box. An upstream promoter element determines the rate at which transcription is initiated and can act in either orientation (Sambrook et al. (1989) “Expression of Cloned Genes in Mammalian Cells.” In Molecular Cloning: A Laboratory Manual, 2nd ed.).
Mammalian viral genes are often highly expressed and have a broad host range; therefore sequences encoding mammalian viral genes provide particularly useful promoter sequences. Examples include the SV40 early promoter, mouse mammary tumor virus LTR promoter, adenovirus major late promoter (Ad MLP), and herpes simplex virus promoter. In addition, sequences derived from non-viral genes, such as the murine metallothionein gene, also provide useful promoter sequences. Expression may be either constitutive or regulated (inducible). Depending on the promoter selected, many promotes may be inducible using known substrates, such as the use of the mouse mammary tumor virus (MMTV) promoter with the glucocorticoid responsive element (GRE) that is induced by glucocorticoid in hormone-responsive transformed cells (see for example, U.S. Pat. No. 5,783,681).
The presence of an enhancer element (enhancer), combined with the promoter elements described above, will usually increase expression levels. An enhancer is a regulatory DNA sequence that can stimulate transcription up to 1000-fold when linked to homologous or heterologous promoters, with synthesis beginning at the normal RNA start site. Enhancers are also active when they are placed upstream or downstream from the transcription initiation site, in either normal or flipped orientation, or at a distance of more than 1000 nucleotides from the promoter (Maniatis et al. (1987) Science 236:1237; Alberts et al. (1989) Molecular Biology of the Cell, 2nd ed.). Enhancer elements derived from viruses may be particularly useful, because they usually have a broader host range. Examples include the SV40 early gene enhancer (Dijkema et al (1985) EMBO J. 4:761) and the enhancer/promoters derived from the long terminal repeat (LTR) of the Rous Sarcoma Virus (Gorman et al. (1982b) Proc. Natl. Acad. Sci. 79:6777) and from human cytomegalovirus (Boshart et al. (1985) Cell 41:521). Additionally, some enhancers are regulatable and become active only in the presence of an inducer, such as a hormone or metal ion (Sassone-Corsi and Borelli (1986) Trends Genet. 2:215; Maniatis et al. (1987) Science 236:1237).
A DNA molecule may be expressed intracellularly in mammalian cells. A promoter sequence may be directly linked with the DNA molecule, in which case the first amino acid at the N-terminus of the recombinant protein will always be a methionine, which is encoded by the ATG start codon. If desired, the N-terminus may be cleaved from the protein by in vitro incubation with cyanogen bromide.
Alternatively, foreign proteins can also be secreted from the cell into the growth media by creating chimeric DNA molecules that encode a fusion protein comprised of a leader sequence fragment that provides for secretion of the foreign protein in mammalian cells. Preferably, there are processing sites encoded between the leader fragment and the foreign gene that can be cleaved either in vivo or in vitro. The leader sequence fragment usually encodes a signal peptide comprised of hydrophobic amino acids which direct the secretion of the protein from the cell. The adenovirus tripartite leader is an example of a leader sequence that provides for secretion of a foreign protein in mammalian cells.
Usually, transcription termination and polyadenylation sequences recognized by mammalian cells are regulatory regions located 3′ to the translation stop codon and thus, together with the promoter elements, flank the coding sequence. The 3′ terminus of the mature mRNA is formed by site-specific post-transcriptional cleavage and polyadenylation (Birnstiel et al. (1985) Cell 41:349; Proudfoot and Whitelaw (1988) “Termination and 3′ end processing of eukaryotic RNA. In Transcription and splicing (ed. B. D. Hames and D. M. Glover); Proudfoot (1989) Trends Biochem. Sci. 14:105). These sequences direct the transcription of an mRNA which can be translated into the polypeptide encoded by the DNA. Examples of transcription terminator/polyadenylation signals include those derived from SV40 (Sambrook et al (1989) “Expression of cloned genes in cultured mammalian cells.” In Molecular Cloning: A Laboratory Manual).
Usually, the above described components, comprising a promoter, polyadenylation signal, and transcription termination sequence are put together into expression constructs. Enhancers, introns with functional splice donor and acceptor sites, and leader sequences may also be included in an expression construct, if desired. Expression constructs are often maintained in a replicon, such as an extrachromosomal element (e.g., plasmids) capable of stable maintenance in a host, such as mammalian cells or bacteria. Mammalian replication systems include those derived from animal viruses, which require trans-acting factors to replicate. For example, plasmids containing the replication systems of papovaviruses, such as SV40 (Gluzman (1981) Cell 23:175) or polyomavirus, replicate to extremely high copy number in the presence of the appropriate viral T antigen. Additional examples of mammalian replicons include those derived from bovine papillomavirus and Epstein-Barr virus. Additionally, the replicon may have two replication systems, thus allowing it to be maintained, for example, in mammalian cells for expression and in a prokaryotic host for cloning and amplification. Examples of such mammalian-bacteria shuttle vectors include pMT2 (Kaufman et al. (1989) Mol. Cell. Biol. 9:946) and pHEBO (Shimizu et al. (1986) Mol. Cell. Biol. 6:1074).
The transformation procedure used depends upon the host to be transformed. Methods for introduction of heterologous polynucleotides into mammalian cells are known in the art and include dextran-mediated transfection, calcium phosphate precipitation, polybrene mediated transfection, protoplast fusion, electroporation, encapsulation of the polynucleotide(s) in liposomes, and direct microinjection of the DNA into nuclei.
Mammalian cell lines available as hosts for expression are known in the art and include many immortalized cell lines available from the American Type Culture Collection (ATCC), including but not limited to, Chinese hamster ovary (CHO) cells, HeLa cells, baby hamster kidney (BHK) cells, monkey kidney cells (COS), human hepatocellular carcinoma cells (e.g., Hep G2), and a number of other cell lines.
ii. Plant Cellular Expression Systems
There are many plant cell culture and whole plant genetic expression systems known in the art. Exemplary plant cellular genetic expression systems include those described in patents, such as: U.S. Pat. No. 5,693,506; U.S. Pat. No. 5,659,122; and U.S. Pat. No. 5,608,143. Additional examples of genetic expression in plant cell culture has been described by Zenk, Phytochemistry 30:3861-3863 (1991). Descriptions of plant protein signal peptides may be found in addition to the references described above in Vaulcombe et al., Mol. Gen. Genet. 209:33-40 (1987); Chandler et al., Plant Molecular Biology 3:407-418 (1984); Rogers, J. Biol. Chem. 260:3731-3738 (1985); Rothstein et al., Gene 55:353-356 (1987); Whittier et al., Nucleic Acids Research 15:2515-2535 (1987); Wirsel et al., Molecular Microbiology 3:3-14 (1989); Yu et al., Gene 122:247-253 (1992). A description of the regulation of plant gene expression by the phytohormone, gibberellic acid and secreted enzymes induced by gibberellic acid can be found in R. L. Jones and J. MacMillin, Gibberellins: in: Advanced Plant Physiology, Malcolm B. Wilkins, ed., 1984 Pitman Publishing Limited, London, pp. 21-52. References that describe other metabolically-regulated genes: Sheen, Plant Cell, 2:1027-1038 (1990); Maas et al., EMBO J. 9:3447-3452 (1990); Benkel and Hickey, Proc. Natl. Acad. Sci. 84:1337-1339 (1987)
Typically, using techniques known in the art, a desired polynucleotide sequence is inserted into an expression cassette comprising genetic regulatory elements designed for operation in plants. The expression cassette is inserted into a desired expression vector with companion sequences upstream and downstream from the expression cassette suitable for expression in a plant host. The companion sequences will be of plasmid or viral origin and provide necessary characteristics to the vector to permit the vectors to move DNA from an original cloning host, such as bacteria, to the desired plant host. The basic bacterial/plant vector construct will preferably provide a broad host range prokaryote replication origin; a prokaryote selectable marker; and, for Agrobacterium transformations, T DNA sequences for Agrobacterium-mediated transfer to plant chromosomes. Where the heterologous gene is not readily amenable to detection, the construct will preferably also have a selectable marker gene suitable for determining if a plant cell has been transformed. A general review of suitable markers, for example for the members of the grass family, is found in Wilmink and Dons, 1993, Plant Mol. Biol. Reptr, 11(2):165-185.
Sequences suitable for permitting integration of the heterologous sequence into the plant genome are also recommended. These might include transposon sequences and the like for homologous recombination as well as Ti sequences which permit random insertion of a heterologous expression cassette into a plant genome. Suitable prokaryote selectable markers include resistance toward antibiotics such as ampicillin or tetracycline. Other DNA sequences encoding additional functions may also be present in the vector, as is known in the art.
The nucleic acid molecules of the subject invention may be included into an expression cassette for expression of the protein(s) of interest. Usually, there will be only one expression cassette, although two or more are feasible. The recombinant expression cassette will contain in addition to the heterologous protein encoding sequence the following elements, a promoter region, plant 5′ untranslated sequences, initiation codon depending upon whether or not the structural gene comes equipped with one, and a transcription and translation termination sequence. Unique restriction enzyme sites at the 5′ and 3′ ends of the cassette allow for easy insertion into a pre-existing vector.
A heterologous coding sequence may be for any protein relating to the present invention. The sequence encoding the protein of interest will encode a signal peptide which allows processing and translocation of the protein, as appropriate, and will usually lack any sequence which might result in the binding of the desired protein of the invention to a membrane. Since, for the most part, the transcriptional initiation region will be for a gene which is expressed and translocated during germination, by employing the signal peptide which provides for translocation, one may also provide for translocation of the protein of interest. In this way, the protein(s) of interest will be translocated from the cells in which they are expressed and may be efficiently harvested. Typically secretion in seeds are across the aleurone or scutellar epithelium layer into the endosperm of the seed. While it is not required that the protein be secreted from the cells in which the protein is produced, this facilitates the isolation and purification of the recombinant protein.
Since the ultimate expression of the desired gene product will be in a eucaryotic cell it is desirable to determine whether any portion of the cloned gene contains sequences which will be processed out as introns by the host's splicosome machinery. If so, site-directed mutagenesis of the “intron” region may be conducted to prevent losing a portion of the genetic message as a false intron code, Reed and Maniatis, Cell 41:95-105, 1985.
The vector can be microinjected directly into plant cells by use of micropipettes to mechanically transfer the recombinant DNA. Crossway, Mol. Gen. Genet, 202:179-185, 1985. The genetic material may also be transferred into the plant cell by using polyethylene glycol, Krens, et al., Nature, 296, 72-74, 1982. Another method of introduction of nucleic acid segments is high velocity ballistic penetration by small particles with the nucleic acid either within the matrix of small beads or particles, or on the surface, Klein, et al., Nature, 327, 70-73, 1987 and Knudsen and Muller, 1991, Planta, 185:330-336 teaching particle bombardment of barley endosperm to create transgenic barley. Yet another method of introduction would be fusion of protoplasts with other entities, either minicells, cells, lysosomes or other fusible lipid-surfaced bodies, Fraley, et al., Proc. Natl. Acad. Sci. USA, 79, 1859-1863, 1982.
The vector may also be introduced into the plant cells by electroporation. (Fromm et al., Proc. Natl. Acad. Sci. USA 82:5824, 1985). In this technique, plant protoplasts are electroporated in the presence of plasmids containing the gene construct. Electrical impulses of high field strength reversibly permeabilize biomembranes allowing the introduction of the plasmids. Electroporated plant protoplasts reform the cell wall, divide, and form plant callus.
All plants from which protoplasts can be isolated and cultured to give whole regenerated plants can be transformed by the present invention so that whole plants are recovered which contain the transferred gene. It is known that practically all plants can be regenerated from cultured cells or tissues, including but not limited to all major species of sugarcane, sugar beet, cotton, fruit and other trees, legumes and vegetables. Some suitable plants include, for example, species from the genera Fragaria, Lotus, Medicago, Onobrychis, Trifolium, Trigonella, Vigna, Citrus, Linum, Geranium, Manihot, Daucus, Arabidopsis, Brassica, Raphanus, Sinapis, Atropa, Capsicum, Datura, Hyoscyamus, Lycopersion, Nicotiana, Solanum, Petunia, Digitalis, Majorana, Cichorium, Helianthus, Lactuca, Bromus, Asparagus, Antirrhinum, Hererocallis, Nemesia, Pelargonium, Panicum, Pennisetum, Ranunculus, Senecio, Salpiglossis, Cucumis, Browaalia, Glycine, Lolium, Zea, Triticum, Sorghum, and Datura. 
Means for regeneration vary from species to species of plants, but generally a suspension of transformed protoplasts containing copies of the heterologous gene is first provided. Callus tissue is formed and shoots may be induced from callus and subsequently rooted. Alternatively, embryo formation can be induced from the protoplast suspension. These embryos germinate as natural embryos to form plants. The culture media will generally contain various amino acids and hormones, such as auxin and cytokinins. It is also advantageous to add glutamic acid and proline to the medium, especially for such species as corn and alfalfa. Shoots and roots normally develop simultaneously. Efficient regeneration will depend on the medium, on the genotype, and on the history of the culture. If these three variables are controlled, then regeneration is fully reproducible and repeatable.
In some plant cell culture systems, the desired protein of the invention may be excreted or alternatively, the protein may be extracted from the whole plant. Where the desired protein of the invention is secreted into the medium, it may be collected. Alternatively, the embryos and embryoless-half seeds or other plant tissue may be mechanically disrupted to release any secreted protein between cells and tissues. The mixture may be suspended in a buffer solution to retrieve soluble proteins. Conventional protein isolation and purification methods will be then used to purify the recombinant protein. Parameters of time, temperature pH, oxygen, and volumes will be adjusted through routine methods to optimize expression and recovery of heterologous protein.
iii. Baculovirus Systems
The polynucleotide encoding the protein can also be inserted into a suitable insect expression vector, and is operably linked to the control elements within that vector. Vector construction employs techniques which are known in the art. Generally, the components of the expression system include a transfer vector, usually a bacterial plasmid, which contains both a fragment of the baculovirus genome, and a convenient restriction site for insertion of the heterologous gene or genes to be expressed; a wild type baculovirus with a sequence homologous to the baculovirus-specific fragment in the transfer vector (this allows for the homologous recombination of the heterologous gene in to the baculovirus genome); and appropriate insect host cells and growth media.
After inserting the DNA sequence encoding the protein into the transfer vector, the vector and the wild type viral genome are transfected into an insect host cell where the vector and viral genome are allowed to recombine. The packaged recombinant virus is expressed and recombinant plaques are identified and purified. Materials and methods for baculovirus/insect cell expression systems are commercially available in kit form from, inter alia, Invitrogen, San Diego Calif. (“MAXBACTM” kit). These techniques are generally known to those skilled in the art and fully described in Summers and Smith, Texas Agricultural Experiment Station Bulletin No. 1555 (1987) (hereinafter “Summers and Smith”).
Prior to inserting the DNA sequence encoding the protein into the baculovirus genome, the above described components, comprising a promoter, leader (if desired), coding sequence of interest, and transcription termination sequence, are usually assembled into an intermediate transplacement construct (transfer vector). This construct may contain a single gene and operably linked regulatory elements; multiple genes, each with its owned set of operably linked regulatory elements; or multiple genes, regulated by the same set of regulatory elements. Intermediate transplacement constructs are often maintained in a replicon, such as an extrachromosomal element (e.g., plasmids) capable of stable maintenance in a host, such as a bacterium. The replicon will have a replication system, thus allowing it to be maintained in a suitable host for cloning and amplification.
Currently, the most commonly used transfer vector for introducing foreign genes into AcNPV is pAc373. Many other vectors, known to those of skill in the art, have also been designed. These include, for example, pVL985 (which alters the polyhedrin start codon from ATG to ATT, and which introduces a BamHI cloning site 32 basepairs downstream from the ATT; see Luckow and Summers, Virology (1989) 17:31.
The plasmid usually also contains the polyhedrin polyadenylation signal (Miller et al. (1988) Ann. Rev. Microbiol., 42:177) and a prokaryotic ampicillin-resistance (amp) gene and origin of replication for selection and propagation in E. coli. 
Baculovirus transfer vectors usually contain a baculovirus promoter. A baculovirus promoter is any DNA sequence capable of binding a baculovirus RNA polymerase and initiating the downstream (5′ to 3′) transcription of a coding sequence (e.g., structural gene) into mRNA. A promoter will have a transcription initiation region which is usually placed proximal to the 5′ end of the coding sequence. This transcription initiation region usually includes an RNA polymerase binding site and a transcription initiation site. A baculovirus transfer vector may also have a second domain called an enhancer, which, if present, is usually distal to the structural gene. Expression may be either regulated or constitutive.
Structural genes, abundantly transcribed at late times in a viral infection cycle, provide particularly useful promoter sequences. Examples include sequences derived from the gene encoding the viral polyhedron protein, Friesen et al., (1986) “The Regulation of Baculovirus Gene Expression,” in: The Molecular Biology of Baculoviruses (ed. Walter Doerfler); EPO Publ. Nos. 127 839 and 155 476; and the gene encoding the p10 protein, Vlak et al., (1988), J. Gen. Virol. 69:765.
DNA encoding suitable signal sequences can be derived from genes for secreted insect or baculovirus proteins, such as the baculovirus polyhedrin gene (Carbonell et al. (1988) Gene, 73:409). Alternatively, since the signals for mammalian cell posttranslational modifications (such as signal peptide cleavage, proteolytic cleavage, and phosphorylation) appear to be recognized by insect cells, and the signals required for secretion and nuclear accumulation also appear to be conserved between the invertebrate cells and vertebrate cells, leaders of non-insect origin, such as those derived from genes encoding human (alpha) α-interferon, Maeda et al., (1985), Nature 315:592; human gastrin-releasing peptide, Lebacq-Verheyden et al., (1988), Molec. Cell. Biol. 8:3129; human IL-2, Smith et al., (1985) Proc. Nat'l Acad. Sci. USA, 82:8404; mouse IL-3, (Miyajima et al., (1987) Gene 58:273; and human glucocerebrosidase, Martin et al. (1988) DNA, 7:99, can also be used to provide for secretion in insects.
A recombinant polypeptide or polyprotein may be expressed intracellularly or, if it is expressed with the proper regulatory sequences, it can be secreted. Good intracellular expression of nonfused foreign proteins usually requires heterologous genes that ideally have a short leader sequence containing suitable translation initiation signals preceding an ATG start signal. If desired, methionine at the N-terminus may be cleaved from the mature protein by in vitro incubation with cyanogen bromide.
Alternatively, recombinant polyproteins or proteins which are not naturally secreted can be secreted from the insect cell by creating chimeric DNA molecules that encode a fusion protein comprised of a leader sequence fragment that provides for secretion of the foreign protein in insects. The leader sequence fragment usually encodes a signal peptide comprised of hydrophobic amino acids which direct the translocation of the protein into the endoplasmic reticulum.
After insertion of the DNA sequence and/or the gene encoding the expression product precursor of the protein, an insect cell host is co-transformed with the heterologous DNA of the transfer vector and the genomic DNA of wild type baculovirus—usually by co-transfection. The promoter and transcription termination sequence of the construct will usually comprise a 2-5 kb section of the baculovirus genome. Methods for introducing heterologous DNA into the desired site in the baculovirus virus are known in the art. (See Summers and Smith supra; Ju et al. (1987); Smith et al., Mol. Cell. Biol. (1983) 3:2156; and Luckow and Summers (1989)). For example, the insertion can be into a gene such as the polyhedrin gene, by homologous double crossover recombination; insertion can also be into a restriction enzyme site engineered into the desired baculovirus gene. Miller et al., (1989), Bioessays 4:91. The DNA sequence, when cloned in place of the polyhedrin gene in the expression vector, is flanked both 5′ and 3′ by polyhedrin-specific sequences and is positioned downstream of the polyhedrin promoter.
The newly formed baculovirus expression vector is subsequently packaged into an infectious recombinant baculovirus. Homologous recombination occurs at low frequency (between about 1% and about 5%); thus, the majority of the virus produced after cotransfection is still wild-type virus. Therefore, a method is necessary to identify recombinant viruses. An advantage of the expression system is a visual screen allowing recombinant viruses to be distinguished. The polyhedrin protein, which is produced by the native virus, is produced at very high levels in the nuclei of infected cells at late times after viral infection. Accumulated polyhedrin protein forms occlusion bodies that also contain embedded particles. These occlusion bodies, up to 15 μm in size, are highly refractile, giving them a bright shiny appearance that is readily visualized under the light microscope. Cells infected with recombinant viruses lack occlusion bodies. To distinguish recombinant virus from wild-type virus, the transfection supernatant is plagued onto a monolayer of insect cells by techniques known to those skilled in the art. Namely, the plaques are screened under the light microscope for the presence (indicative of wild-type virus) or absence (indicative of recombinant virus) of occlusion bodies. Current Protocols in Microbiology Vol. 2 (Ausubel et al. eds) at 16.8 (Supp. 10, 1990); Summers and Smith, supra; Miller et al. (1989).
Recombinant baculovirus expression vectors have been developed for infection into several insect cells. For example, recombinant baculoviruses have been developed for, inter alia: Aedes aegypti, Autographa californica, Bombyx mori, Drosophila melanogaster, Spodoptera frugiperda, and Trichoplusia ni (PCT Pub. No. WO 89/046699; Carbonell et al., (1985) J. Virol. 56:153; Wright (1986) Nature 321:718; Smith et al., (1983) Mol. Cell. Biol. 3:2156; and see generally, Fraser, et al. (1989) In Vitro Cell. Dev. Biol. 25:225).
Cells and cell culture media are commercially available for both direct and fusion expression of heterologous polypeptides in a baculovirus/expression system; cell culture technology is generally known to those skilled in the art. See, e.g., Summers and Smith supra.
The modified insect cells may then be grown in an appropriate nutrient medium, which allows for stable maintenance of the plasmid(s) present in the modified insect host. Where the expression product gene is under inducible control, the host may be grown to high density, and expression induced. Alternatively, where expression is constitutive, the product will be continuously expressed into the medium and the nutrient medium must be continuously circulated, while removing the product of interest and augmenting depleted nutrients. The product may be purified by such techniques as chromatography, e.g., HPLC, affinity chromatography, ion exchange chromatography, etc.; electrophoresis; density gradient centrifugation; solvent extraction, or the like. As appropriate, the product may be further purified, as required, so as to remove substantially any insect proteins which are also secreted in the medium or result from lysis of insect cells, so as to provide a product which is at least substantially free of host debris, e.g., proteins, lipids and polysaccharides.
In order to obtain protein expression, recombinant host cells derived from the transformants are incubated under conditions which allow expression of the recombinant protein encoding sequence. These conditions will vary, dependent upon the host cell selected. However, the conditions are readily ascertainable to those of ordinary skill in the art, based upon what is known in the art.
iv. Bacterial Systems
Bacterial expression techniques are known in the art. A bacterial promoter is any DNA sequence capable of binding bacterial RNA polymerase and initiating the downstream (3′) transcription of a coding sequence (e.g. structural gene) into mRNA. A promoter will have a transcription initiation region which is usually placed proximal to the 5′ end of the coding sequence. This transcription initiation region usually includes an RNA polymerase binding site and a transcription initiation site. A bacterial promoter may also have a second domain called an operator, that may overlap an adjacent RNA polymerase binding site at which RNA synthesis begins. The operator permits negative regulated (inducible) transcription, as a gene repressor protein may bind the operator and thereby inhibit transcription of a specific gene. Constitutive expression may occur in the absence of negative regulatory elements, such as the operator. In addition, positive regulation may be achieved by a gene activator protein binding sequence, which, if present is usually proximal (5′) to the RNA polymerase binding sequence. An example of a gene activator protein is the catabolite activator protein (CAP), which helps initiate transcription of the lac operon in Escherichia coli (E. coli) (Raibaud et al. (1984) Annu. Rev. Genet. 18:173). Regulated expression may therefore be either positive or negative, thereby either enhancing or reducing transcription.
Sequences encoding metabolic pathway enzymes provide particularly useful promoter sequences. Examples include promoter sequences derived from sugar metabolizing enzymes, such as galactose, lactose (lac) (Chang et al. (1977) Nature 198:1056), and maltose. Additional examples include promoter sequences derived from biosynthetic enzymes such as tryptophan (trp) (Goeddel et al. (1980) Nuc. Acids Res. 8:4057; Yelverton et al. (1981) Nucl. Acids Res. 9:731; U.S. Pat. No. 4,738,921; EPO Publ. Nos. 036 776 and 121 775). The beta-lactamase (bla) promoter system (Weissmann (1981) “The cloning of interferon and other mistakes.” In Interferon 3 (ed. I. Gresser)), bacteriophage lambda PL (Shimatake et al. (1981) Nature 292:128) and T5 (U.S. Pat. No. 4,689,406) promoter systems also provide useful promoter sequences.
In addition, synthetic promoters which do not occur in nature also function as bacterial promoters. For example, transcription activation sequences of one bacterial or bacteriophage promoter may be joined with the operon sequences of another bacterial or bacteriophage promoter, creating a synthetic hybrid promoter (U.S. Pat. No. 4,551,433). For example, the tac promoter is a hybrid trp-lac promoter comprised of both trp promoter and lac operon sequences that is regulated by the lac repressor (Amann et al. (1983) Gene 25:167; de Boer et al. (1983) Proc. Natl. Acad. Sci. 80:21). Furthermore, a bacterial promoter can include naturally occurring promoters of non-bacterial origin that have the ability to bind bacterial RNA polymerase and initiate transcription. A naturally occurring promoter of non-bacterial origin can also be coupled with a compatible RNA polymerase to produce high levels of expression of some genes in prokaryotes. The bacteriophage T7 RNA polymerase/promoter system is an example of a coupled promoter system (Studier et al. (1986) J. Mol. Biol. 189:113; Tabor et al. (1985) Proc Natl. Acad. Sci. 82:1074). In addition, a hybrid promoter can also be comprised of a bacteriophage promoter and an E. coli operator region (EPO Publ. No. 267 851).
In addition to a functioning promoter sequence, an efficient ribosome binding site is also useful for the expression of foreign genes in prokaryotes. In E. coli, the ribosome binding site is called the Shine-Dalgarno (SD) sequence and includes an initiation codon (ATG) and a sequence 3-9 nucleotides in length located 3-11 nucleotides upstream of the initiation codon (Shine et al. (1975) Nature 254:34). The SD sequence is thought to promote binding of mRNA to the ribosome by the pairing of bases between the SD sequence and the 3′ end of E. coli 16S rRNA (Steitz et al. (1979) “Genetic signals and nucleotide sequences in messenger RNA.” In Biological Regulation and Development: Gene Expression (ed. R. F. Goldberger)). To express eukaryotic genes and prokaryotic genes with weak ribosome-binding site, it is often necessary to optimize the distance between the SD sequence and the ATG of the eukaryotic gene (Sambrook et al. (1989) “Expression of cloned genes in Escherichia coli.” In Molecular Cloning: A Laboratory Manual).
A DNA molecule may be expressed intracellularly. A promoter sequence may be directly linked with the DNA molecule, in which case the first amino acid at the N-terminus will always be a methionine, which is encoded by the ATG start codon. If desired, methionine at the N-terminus may be cleaved from the protein by in vitro incubation with cyanogen bromide or by either in vivo or in vitro incubation with a bacterial methionine N-terminal peptidase (EPO Publ. No. 219 237).
Fusion proteins provide an alternative to direct expression. Usually, a DNA sequence encoding the N-terminal portion of an endogenous bacterial protein, or other stable protein, is fused to the 5′ end of heterologous coding sequences. Upon expression, this construct will provide a fusion of the two amino acid sequences. For example, the bacteriophage lambda cell gene can be linked at the 5′ terminus of a foreign gene and expressed in bacteria. The resulting fusion protein preferably retains a site for a processing enzyme (factor Xa) to cleave the bacteriophage protein from the foreign gene (Nagai et al. (1984) Nature 309:810). Fusion proteins can also be made with sequences from the lacZ (Jia et al. (1987) Gene 60:197), trpE (Allen et al. (1987) J. Biotechnol. 5:93; Makoff et al. (1989) J. Gen. Microbiol. 135:11), and Chey (EPO Publ. No. 324 647) genes. The DNA sequence at the junction of the two amino acid sequences may or may not encode a cleavable site. Another example is a ubiquitin fusion protein. Such a fusion protein is made with the ubiquitin region that preferably retains a site for a processing enzyme (e.g. ubiquitin specific processing-protease) to cleave the ubiquitin from the foreign protein. Through this method, native foreign protein can be isolated (Miller et al. (1989) Bio/Technology 7:698).
Alternatively, foreign proteins can also be secreted from the cell by creating chimeric DNA molecules that encode a fusion protein comprised of a signal peptide sequence fragment that provides for secretion of the foreign protein in bacteria (U.S. Pat. No. 4,336,336). The signal sequence fragment usually encodes a signal peptide comprised of hydrophobic amino acids which direct the secretion of the protein from the cell. The protein is either secreted into the growth media (gram-positive bacteria) or into the periplasmic space, located between the inner and outer membrane of the cell (gram-negative bacteria). Preferably there are processing sites, which can be cleaved either in vivo or in vitro encoded between the signal peptide fragment and the foreign gene.
DNA encoding suitable signal sequences can be derived from genes for secreted bacterial proteins, such as the E. coli outer membrane protein gene (ompA) (Masui et al. (1983), in: Experimental Manipulation of Gene Expression; Ghrayeb et al. (1984) EMBO J. 3:2437) and the E. coli alkaline phosphatase signal sequence (phoA) (Oka et al. (1985) Proc. Natl. Acad. Sci. 82:7212). As an additional example, the signal sequence of the alpha-amylase gene from various Bacillus strains can be used to secrete heterologous proteins from B. subtilis (Palva et al. (1982) Proc. Natl. Acad. Sci. USA 79:5582; EPO Publ. No. 244 042).
Usually, transcription termination sequences recognized by bacteria are regulatory regions located 3′ to the translation stop codon, and thus together with the promoter flank the coding sequence. These sequences direct the transcription of an mRNA which can be translated into the polypeptide encoded by the DNA. Transcription termination sequences frequently include DNA sequences of about 50 nucleotides capable of forming stem loop structures that aid in terminating transcription. Examples include transcription termination sequences derived from genes with strong promoters, such as the trp gene in E. coli as well as other biosynthetic genes.
Usually, the above described components, comprising a promoter, signal sequence (if desired), coding sequence of interest, and transcription termination sequence, are put together into expression constructs. Expression constructs are often maintained in a replicon, such as an extrachromosomal element (e.g., plasmids) capable of stable maintenance in a host, such as bacteria. The replicon will have a replication system, thus allowing it to be maintained in a prokaryotic host either for expression or for cloning and amplification. In addition, a replicon may be either a high or low copy number plasmid. A high copy number plasmid will generally have a copy number ranging from about 5 to about 200, and usually about 10 to about 150. A host containing a high copy number plasmid will preferably contain at least about 10, and more preferably at least about 20 plasmids. Either a high or low copy number vector may be selected, depending upon the effect of the vector and the foreign protein on the host.
Alternatively, the expression constructs can be integrated into the bacterial genome with an integrating vector. Integrating vectors usually contain at least one sequence homologous to the bacterial chromosome that allows the vector to integrate. Integrations appear to result from recombinations between homologous DNA in the vector and the bacterial chromosome. For example, integrating vectors constructed with DNA from various Bacillus strains integrate into the Bacillus chromosome (EPO Publ. No. 127 328). Integrating vectors may also be comprised of bacteriophage or transposon sequences.
Usually, extrachromosomal and integrating expression constructs may contain selectable markers to allow for the selection of bacterial strains that have been transformed. Selectable markers can be expressed in the bacterial host and may include genes which render bacteria resistant to drugs such as ampicillin, chloramphenicol, erythromycin, kanamycin (neomycin), and tetracycline (Davies et al. (1978) Annu. Rev. Microbiol. 32:469). Selectable markers may also include biosynthetic genes, such as those in the histidine, tryptophan, and leucine biosynthetic pathways.
Alternatively, some of the above described components can be put together in transformation vectors. Transformation vectors are usually comprised of a selectable market that is either maintained in a replicon or developed into an integrating vector, as described above. Expression and transformation vectors, either extra-chromosomal replicons or integrating vectors, have been developed for transformation into many bacteria. For example, expression vectors have been developed for, inter alia, the following bacteria: Bacillus subtilis (Palva et al. (1982) Proc. Natl. Acad. Sci. USA 79:5582; EPO Publ. Nos. 036 259 and 063 953; PCT Publ. No. WO 84/04541), Escherichia coli (Shimatake et al. (1981) Nature 292:128; Amann et al. (1985) Gene 40:183; Studier et al. (1986) J. Mol. Biol. 189:113; EPO Publ. Nos. 036 776, 136 829 and 136 907), Streptococcus cremoris (Powell et al. (1988) Appl. Environ. Microbiol. 54:655); Streptococcus lividans (Powell et al. (1988) Appl. Environ. Microbiol. 54:655), Streptomyces lividans (U.S. Pat. No. 4,745,056).
Methods of introducing exogenous DNA into bacterial hosts are well-known in the art, and usually include either the transformation of bacteria treated with CaCl2 or other agents, such as divalent cations and DMSO. DNA can also be introduced into bacterial cells by electroporation. Transformation procedures usually vary with the bacterial species to be transformed. (See e.g., use of Bacillus: Masson et al. (1989) FEMS Microbiol. Lett. 60:273; Palva et al. (1982) Proc. Natl. Acad. Sci. USA 79:5582; EPO Publ. Nos. 036 259 and 063 953; PCT Publ. No. WO 84/04541; use of Campylobacter: Miller et al. (1988) Proc. Natl. Acad. Sci. 85:856; and Wang et al. (1990) J. Bacteriol. 172:949; use of Escherichia coli: Cohen et al. (1973) Proc. Natl. Acad. Sci. 69:2110; Dower et al. (1988) Nucleic Acids Res. 16:6127; Kushner (1978) “An improved method for transformation of Escherichia coli with ColE1-derived plasmids. In Genetic Engineering: Proceedings of the International Symposium on Genetic Engineering (eds. H. W. Boyer and S, Nicosia); Mandel et al. (1970) J. Mol. Biol. 53:159; Taketo (1988) Biochim. Biophys. Acta 949:318; use of Lactobacillus: Chassy et al. (1987) FEMS Microbiol. Lett. 44:173; use of Pseudomonas: Fiedler et al. (1988) Anal. Biochem 170:38; use of Staphylococcus: Augustin et al. (1990) FEMS Microbiol. Lett. 66:203; use of Streptococcus: Barany et al. (1980) J. Bacteriol. 144:698; Harlander (1987) “Transformation of Streptococcus lactis by electroporation, in: Streptococcal Genetics (ed. J. Ferretti and R. Curtiss I I I); Perry et al. (1981) Infect. Immun. 32:1295; Powell et al. (1988) Appl. Environ. Microbiol. 54:655; Somkuti et al. (1987) Proc. 4th Evr. Cong. Biotechnology 1:412.
v. Yeast Expression
Yeast expression systems are also known to one of ordinary skill in the art. A yeast promoter is any DNA sequence capable of binding yeast RNA polymerase and initiating the downstream (3′) transcription of a coding sequence (e.g. structural gene) into mRNA. A promoter will have a transcription initiation region which is usually placed proximal to the 5′ end of the coding sequence. This transcription initiation region usually includes an RNA polymerase binding site (the “TATA Box”) and a transcription initiation site. A yeast promoter may also have a second domain called an upstream activator sequence (UAS), which, if present, is usually distal to the structural gene. The UAS permits regulated (inducible) expression. Constitutive expression occurs in the absence of a UAS. Regulated expression may be either positive or negative, thereby either enhancing or reducing transcription.
Yeast is a fermenting organism with an active metabolic pathway, therefore sequences encoding enzymes in the metabolic pathway provide particularly useful promoter sequences. Examples include alcohol dehydrogenase (ADH) (EPO Publ. No. 284 044), enolase, glucokinase, glucose-6-phosphate isomerase, glyceraldehyde-3-phosphate-dehydrogenase (GAP or GAPDH), hexokinase, phosphofructokinase, 3-phosphoglycerate mutase, and pyruvate kinase (PyK) (EPO Publ. No. 329 203). The yeast PHO5 gene, encoding acid phosphatase, also provides useful promoter sequences (Myanohara et al. (1983) Proc. Natl. Acad. Sci. USA 80:1).
In addition, synthetic promoters which do not occur in nature also function as yeast promoters. For example, UAS sequences of one yeast promoter may be joined with the transcription activation region of another yeast promoter, creating a synthetic hybrid promoter. Examples of such hybrid promoters include the ADH regulatory sequence linked to the GAP transcription activation region (U.S. Pat. Nos. 4,876,197 and 4,880,734). Other examples of hybrid promoters include promoters which consist of the regulatory sequences of either the ADH2, GAL4, GAL10, OR PHO5 genes, combined with the transcriptional activation region of a glycolytic enzyme gene such as GAP or PyK (EPO Publ. No. 164 556). Furthermore, a yeast promoter can include naturally occurring promoters of non-yeast origin that have the ability to bind yeast RNA polymerase and initiate transcription. Examples of such promoters include, inter alia, (Cohen et al. (1980) Proc. Natl. Acad. Sci. USA 77:1078; Henikoff et al. (1981) Nature 283:835; Hollenberg et al. (1981) Curr. Topics Microbiol. Immunol. 96:119; Hollenberg et al. (1979) “The Expression of Bacterial Antibiotic Resistance Genes in the Yeast Saccharomyces cerevisiae,” in: Plasmids of Medical, Environmental and Commercial Importance (eds. K. N. Timmis and A. Puhler); Mercerau-Puigalon et al. (1980) Gene 11:163; Panthier et al. (1980) Curr. Genet. 2:109).
A DNA molecule may be expressed intracellularly in yeast. A promoter sequence may be directly linked with the DNA molecule, in which case the first amino acid at the N-terminus of the recombinant protein will always be a methionine, which is encoded by the ATG start codon. If desired, methionine at the N-terminus may be cleaved from the protein by in vitro incubation with cyanogen bromide.
Fusion proteins provide an alternative for yeast expression systems, as well as in mammalian, plant, baculovirus, and bacterial expression systems. Usually, a DNA sequence encoding the N-terminal portion of an endogenous yeast protein, or other stable protein, is fused to the 5′ end of heterologous coding sequences. Upon expression, this construct will provide a fusion of the two amino acid sequences. For example, the yeast or human superoxide dismutase (SOD) gene, can be linked at the 5′ terminus of a foreign gene and expressed in yeast. The DNA sequence at the junction of the two amino acid sequences may or may not encode a cleavable site. See e.g., EPO Publ. No. 196056. Another example is a ubiquitin fusion protein. Such a fusion protein is made with the ubiquitin region that preferably retains a site for a processing enzyme (e.g. ubiquitin-specific processing protease) to cleave the ubiquitin from the foreign protein. Through this method, therefore, native foreign protein can be isolated (e.g., WO88/024066).
Alternatively, foreign proteins can also be secreted from the cell into the growth media by creating chimeric DNA molecules that encode a fusion protein comprised of a leader sequence fragment that provide for secretion in yeast of the foreign protein. Preferably, there are processing sites encoded between the leader fragment and the foreign gene that can be cleaved either in vivo or in vitro. The leader sequence fragment usually encodes a signal peptide comprised of hydrophobic amino acids which direct the secretion of the protein from the cell.
DNA encoding suitable signal sequences can be derived from genes for secreted yeast proteins, such as the yeast invertase gene (EPO Publ. No. 012 873; JPO Publ. No. 62:096,086) and the A-factor gene (U.S. Pat. No. 4,588,684). Alternatively, leaders of non-yeast origin, such as an interferon leader, exist that also provide for secretion in yeast (EPO Publ. No. 060 057).
A preferred class of secretion leaders are those that employ a fragment of the yeast alpha-factor gene, which contains both a “pre” signal sequence, and a “pro” region. The types of alpha-factor fragments that can be employed include the full-length pre-pro alpha factor leader (about 83 amino acid residues) as well as truncated alpha-factor leaders (usually about 25 to about 50 amino acid residues) (U.S. Pat. Nos. 4,546,083 and 4,870,008; EPO Publ. No. 324 274). Additional leaders employing an alpha-factor leader fragment that provides for secretion include hybrid alpha-factor leaders made with a presequence of a first yeast, but a pro-region from a second yeast alphafactor. (See e.g., PCT Publ. No. WO 89/02463.)
Usually, transcription termination sequences recognized by yeast are regulatory regions located 3′ to the translation stop codon, and thus together with the promoter flank the coding sequence. These sequences direct the transcription of an mRNA which can be translated into the polypeptide encoded by the DNA. Examples of transcription terminator sequence and other yeast-recognized termination sequences, such as those coding for glycolytic enzymes.
Usually, the above described components, comprising a promoter, leader (if desired), coding sequence of interest, and transcription termination sequence, are put together into expression constructs. Expression constructs are often maintained in a replicon, such as an extrachromosomal element (e.g., plasmids) capable of stable maintenance in a host, such as yeast or bacteria. The replicon may have two replication systems, thus allowing it to be maintained, for example, in yeast for expression and in a prokaryotic host for cloning and amplification. Examples of such yeast-bacteria shuttle vectors include YEp24 (Botstein et al. (1979) Gene 8:17-24), pC1/1 (Brake et al. (1984) Proc. Natl. Acad. Sci. USA 81:4642-4646), and YRp17 (Stinchcomb et al. (1982) J. Mol. Biol. 158:157). In addition, a replicon may be either a high or low copy number plasmid. A high copy number plasmid will generally have a copy number ranging from about 5 to about 200, and usually about 10 to about 150. A host containing a high copy number plasmid will preferably have at least about 10, and more preferably at least about 20. Enter a high or low copy number vector may be selected, depending upon the effect of the vector and the foreign protein on the host. See e.g., Brake et al., supra.
Alternatively, the expression constructs can be integrated into the yeast genome with an integrating vector. Integrating vectors usually contain at least one sequence homologous to a yeast chromosome that allows the vector to integrate, and preferably contain two homologous sequences flanking the expression construct. Integrations appear to result from recombinations between homologous DNA in the vector and the yeast chromosome (Orr-Weaver et al. (1983) Methods in Enzymol. 101:228-245). An integrating vector may be directed to a specific locus in yeast by selecting the appropriate homologous sequence for inclusion in the vector. See Orr-Weaver et al., supra. One or more expression construct may integrate, possibly affecting levels of recombinant protein produced (Rine et al. (1983) Proc. Natl. Acad. Sci. USA 80:6750). The chromosomal sequences included in the vector can occur either as a single segment in the vector, which results in the integration of the entire vector, or two segments homologous to adjacent segments in the chromosome and flanking the expression construct in the vector, which can result in the stable integration of only the expression construct.
Usually, extrachromosomal and integrating expression constructs may contain selectable markers to allow for the selection of yeast strains that have been transformed. Selectable markers may include biosynthetic genes that can be expressed in the yeast host, such as ADE2, HIS4, LEU2, TRP1, and ALG7, and the G418 resistance gene, which confer resistance in yeast cells to tunicamycin and G418, respectively. In addition, a suitable selectable marker may also provide yeast with the ability to grow in the presence of toxic compounds, such as metal. For example, the presence of CUP1 allows yeast to grow in the presence of copper ions (Butt et al. (1987) Microbiol, Rev. 51:351).
Alternatively, some of the above described components can be put together into transformation vectors. Transformation vectors are usually comprised of a selectable marker that is either maintained in a replicon or developed into an integrating vector, as described above.
Expression and transformation vectors, either extrachromosomal replicons or integrating vectors, have been developed for transformation into many yeasts. For example, expression vectors and methods of introducing exogenous DNA into yeast hosts have been developed for, inter alia, the following yeasts: Candida albicans (Kurtz, et al. (1986) Mol. Cell. Biol. 6:142); Candida maltosa (Kunze, et al. (1985) J. Basic Microbiol. 25:141); Hansenula polymorpha (Gleeson, et al. (1986) J. Gen. Microbiol. 132:3459; Roggenkamp et al. (1986) Mol. Gen. Genet. 202:302); Kluyveromyces fragilis (Das, et al. (1984) J. Bacteriol. 158:1165); Kluyveromyces lactis (De Louvencourt et al. (1983) J. Bacteriol. 154:737; Van den Berg et al. (1990) Bio/Technology 8:135); Pichia guillerimondii (Kunze et al. (1985) J. Basic Microbiol. 25:141); Pichia pastoris (Cregg, et al. (1985) Mol. Cell. Biol. 5:3376; U.S. Pat. Nos. 4,837,148 and 4,929,555); Saccharomyces cerevisiae (Hinnen et al. (1978) Proc. Natl. Acad. Sci. USA 75:1929; Ito et al. (1983) J. Bacteriol. 153:163); Schizosaccharomyces pombe (Beach and Nurse (1981) Nature 300:706); and Yarrowia lipolytica (Davidow, et al. (1985) Curr. Genet. 10:380471 Gaillardin, et al. (1985) Curr. Genet. 10:49).
Methods of introducing exogenous DNA into yeast hosts are well-known in the art, and usually include either the transformation of spheroplasts or of intact yeast cells treated with alkali cations. Transformation procedures usually vary with the yeast species to be transformed. See e.g., [Kurtz et al. (1986) Mol. Cell. Biol. 6:142; Kunze et al. (1985) J. Basic Microbiol. 25:141; Candida]; [Gleeson et al. (1986) J. Gen. Microbiol. 132:3459; Roggenkamp et al. (1986) Mol. Gen. Genet. 202:302; Hansenula]; [Das et al. (1984) J. Bacteriol. 158:1165; De Louvencourt et al. (1983) J. Bacteriol. 154:1165; Van den Berg et al. (1990) Bio/Technology 8:135; Kluyveromyces]; [Cregg et al. (1985) Mol. Cell. Biol. 5:3376; Kunze et al. (1985) J. Basic Microbiol. 25:141; U.S. Pat. Nos. 4,837,148 and 4,929,555; Pichia]; [Hinnen et al. (1978) Proc. Natl. Acad. Sci. USA 75; 1929; Ito et al. (1983) J. Bacteriol. 153:163 Saccharomyces]; [Beach and Nurse (1981) Nature 300:706; Schizosaccharomyces]; [Davidow et al. (1985) Curr. Genet. 10:39; Gaillardin et al. (1985) Curr. Genet. 10:49; Yarrowia]. 
DEFINITIONS
A composition containing X is “substantially free of” Y when at least 85% by weight of the total X+Y in the composition is X. Preferably, X comprises at least about 90% by weight of the total of X+Y in the composition, more preferably at least about 95% or even 99% by weight.
A “conserved” Neisseria amino acid fragment or protein is one that is present in a particular Neisserial protein in at least x % of Neisseria. The value of x may be 50% or more, e.g., 66%, 75%, 80%, 90%, 95% or even 100% (i.e. the amino acid is found in the protein in question in all Neisseria). In order to determine whether an amino acid is “conserved” in a particular Neisserial protein, it is necessary to compare that amino acid residue in the sequences of the protein in question from a plurality of different Neisseria (a reference population). The reference population may include a number of different Neisseria species or may include a single species. The reference population may include a number of different serogroups of a particular species or a single serogroup. A preferred reference population consists of the 5 most common Neisseria The term “heterologous” refers to two biological components that are not found together in nature. The components may be host cells, genes, or regulatory regions, such as promoters. Although the heterologous components are not found together in nature, they can function together, as when a promoter heterologous to a gene is operably linked to the gene. Another example is where a Neisserial sequence is heterologous to a mouse host cell.
An “origin of replication” is a polynucleotide sequence that initiates and regulates replication of polynucleotides, such as an expression vector. The origin of replication behaves as an autonomous unit of polynucleotide replication within a cell, capable of replication under its own control. An origin of replication may be needed for a vector to replicate in a particular host cell. With certain origins of replication, an expression vector can be reproduced at a high copy number in the presence of the appropriate proteins within the cell. Examples of origins are the autonomously replicating sequences, which are effective in yeast; and the viral T-antigen, effective in COS-7 cells.
A “mutant” sequence is defined as a DNA, RNA or amino acid sequence differing from but having homology with the native or disclosed sequence. Depending on the particular sequence, the degree of homology (sequence identity) between the native or disclosed sequence and the mutant sequence is preferably greater than 50% (e.g., 60%, 70%, 80%, 90%, 95%, 99% or more) which is calculated as described above. As used herein, an “allelic variant” of a nucleic acid molecule, or region, for which nucleic acid sequence is provided herein is a nucleic acid molecule, or region, that occurs at essentially the same locus in the genome of another or second isolate, and that, due to natural variation caused by, for example, mutation or recombination, has a similar but not identical nucleic acid sequence. A coding region allelic variant typically encodes a protein having similar activity to that of the protein encoded by the gene to which it is being compared. An allelic variant can also comprise an alteration in the 5′ or 3′ untranslated regions of the gene, such as in regulatory control regions. (see, for example, U.S. Pat. No. 5,753,235).
Antibodies
As used herein, the term “antibody” refers to a polypeptide or group of polypeptides composed of at least one antibody combining site. An “antibody combining site” is the three-dimensional binding space with an internal surface shape and charge distribution complementary to the features of an epitope of an antigen, which allows a binding of the antibody with the antigen. “Antibody” includes, for example, vertebrate antibodies, hybrid antibodies, chimeric antibodies, humanized antibodies, altered antibodies, univalent antibodies, Fab proteins, and single domain antibodies.
Antibodies against the proteins of the invention are useful for affinity chromatography, immunoassays, and distinguishing/identifying Neisseria menB proteins. Antibodies elicited against the proteins of the present invention bind to antigenic polypeptides or proteins or protein fragments that are present and specifically associated with strains of Neisseria meningitidis menB. In some instances, these antigens may be associated with specific strains, such as those antigens specific for the menB strains. The antibodies of the invention may be immobilized to a matrix and utilized in an immunoassay or on an affinity chromatography column, to enable the detection and/or separation of polypeptides, proteins or protein fragments or cells comprising such polypeptides, proteins or protein fragments. Alternatively, such polypeptides, proteins or protein fragments may be immobilized so as to detect antibodies bindably specific thereto.
Antibodies to the proteins of the invention, both polyclonal and monoclonal, may be prepared by conventional methods. In general, the protein is first used to immunize a suitable animal, preferably a mouse, rat, rabbit or goat. Rabbits and goats are preferred for the preparation of polyclonal sera due to the volume of serum obtainable, and the availability of labeled anti-rabbit and anti-goat antibodies. Immunization is generally performed by mixing or emulsifying the protein in saline, preferably in an adjuvant such as Freund's complete adjuvant, and injecting the mixture or emulsion parenterally (generally subcutaneously or intramuscularly). A dose of 50-200 μg/injection is typically sufficient. Immunization is generally boosted 2-6 weeks later with one or more injections of the protein in saline, preferably using Freund's incomplete adjuvant. One may alternatively generate antibodies by in vitro immunization using methods known in the art, which for the purposes of this invention is considered equivalent to in vivo immunization. Polyclonal antisera is obtained by bleeding the immunized animal into a glass or plastic container, incubating the blood at 25° C. for one hour, followed by incubating at 4° C. for 2-18 hours. The serum is recovered by centrifugation (e.g., 1,000 g for 10 minutes). About 20-50 ml per bleed may be obtained from rabbits.
Monoclonal antibodies are prepared using the standard method of Kohler & Milstein (Nature (1975) 256:495-96), or a modification thereof. Typically, a mouse or rat is immunized as described above. However, rather than bleeding the animal to extract serum, the spleen (and optionally several large lymph nodes) is removed and dissociated into single cells. If desired, the spleen cells may be screened (after removal of nonspecifically adherent cells) by applying a cell suspension to a plate or well coated with the protein antigen. B-cells that express membrane-bound immunoglobulin specific for the antigen bind to the plate, and are not rinsed away with the rest of the suspension. Resulting B-cells, or all dissociated spleen cells, are then induced to fuse with myeloma cells to form hybridomas, and are cultured in a selective medium (e.g., hypoxanthine, aminopterin, thymidine medium, “HAT”). The resulting hybridomas are plated by limiting dilution, and are assayed for the production of antibodies which bind specifically to the immunizing antigen (and which do not bind to unrelated antigens). The selected MAb-secreting hybridomas are then cultured either in vitro (e.g., in tissue culture bottles or hollow fiber reactors), or in vivo (as ascites in mice).
If desired, the antibodies (whether polyclonal or monoclonal) may be labeled using conventional techniques. Suitable labels include fluorophores, chromophores, radioactive atoms (particularly 32P and 125I), electron-dense reagents, enzymes, and ligands having specific binding partners. Enzymes are typically detected by their activity. For example, horseradish peroxidase is usually detected by its ability to convert 3,3′,5,5′-tetramethylbenzidine (TMB) to a blue pigment, quantifiable with a spectrophotometer. “Specific binding partner” refers to a protein capable of binding a ligand molecule with high specificity, as for example in the case of an antigen and a monoclonal antibody specific therefor. Other specific binding partners include biotin and avidin or streptavidin, IgG and protein A, and the numerous receptor-ligand couples known in the art. It should be understood that the above description is not meant to categorize the various labels into distinct classes, as the same label may serve in several different modes. For example, 125I may serve as a radioactive label or as an electron-dense reagent. HRP may serve as enzyme or as antigen for a MAb. Further, one may combine various labels for desired effect. For example, MAbs and avidin also require labels in the practice of this invention: thus, one might label a MAb with biotin, and detect its presence with avidin labeled with 125I, or with an anti-biotin MAb labeled with HRP. Other permutations and possibilities will be readily apparent to those of ordinary skill in the art, and are considered as equivalents within the scope of the instant invention.
Antigens, immunogens, polypeptides, proteins or protein fragments of the present invention elicit formation of specific binding partner antibodies. These antigens, immunogens, polypeptides, proteins or protein fragments of the present invention comprise immunogenic compositions of the present invention. Such immunogenic compositions may further comprise or include adjuvants, carriers, or other compositions that promote or enhance or stabilize the antigens, polypeptides, proteins or protein fragments of the present invention. Such adjuvants and carriers will be readily apparent to those of ordinary skill in the art.
Pharmaceutical Compositions
Pharmaceutical compositions can comprise (include) either polypeptides, antibodies, or nucleic acid of the invention. The pharmaceutical compositions will comprise a therapeutically effective amount of either polypeptides, antibodies, or polynucleotides of the claimed invention.
The term “therapeutically effective amount” as used herein refers to an amount of a therapeutic agent to treat, ameliorate, or prevent a desired disease or condition, or to exhibit a detectable therapeutic or preventative effect. The effect can be detected by, for example, chemical markers or antigen levels. Therapeutic effects also include reduction in physical symptoms, such as decreased body temperature, when given to a patient that is febrile. The precise effective amount for a subject will depend upon the subject's size and health, the nature and extent of the condition, and the therapeutics or combination of therapeutics selected for administration. Thus, it is not useful to specify an exact effective amount in advance. However, the effective amount for a given situation can be determined by routine experimentation and is within the judgment of the clinician.
For purposes of the present invention, an effective dose will be from about 0.01 mg/kg to 50 mg/kg or 0.05 mg/kg to about 10 mg/kg of the DNA constructs in the individual to which it is administered.
A pharmaceutical composition can also contain a pharmaceutically acceptable carrier. The term “pharmaceutically acceptable carrier” refers to a carrier for administration of a therapeutic agent, such as antibodies or a polypeptide, genes, and other therapeutic agents. The term refers to any pharmaceutical carrier that does not itself induce the production of antibodies harmful to the individual receiving the composition, and which may be administered without undue toxicity. Suitable carriers may be large, slowly metabolized macromolecules such as proteins, polysaccharides, polylactic acids, polyglycolic acids, polymeric amino acids, amino acid copolymers, and inactive virus particles. Such carriers are well known to those of ordinary skill in the art.
Pharmaceutically acceptable salts can be used therein, for example, mineral acid salts such as hydrochlorides, hydrobromides, phosphates, sulfates, and the like; and the salts of organic acids such as acetates, propionates, malonates, benzoates, and the like. A thorough discussion of pharmaceutically acceptable excipients is available in Remington's Pharmaceutical Sciences (Mack Pub. Co., N.J. 1991).
Pharmaceutically acceptable carriers in therapeutic compositions may contain liquids such as water, saline, glycerol and ethanol. Additionally, auxiliary substances, such as wetting or emulsifying agents, pH buffering substances, and the like, may be present in such vehicles. Typically, the therapeutic compositions are prepared as injectables, either as liquid solutions or suspensions; solid forms suitable for solution in, or suspension in, liquid vehicles prior to injection may also be prepared. Liposomes are included within the definition of a pharmaceutically acceptable carrier.
Delivery Methods
Once formulated, the compositions of the invention can be administered directly to the subject. The subjects to be treated can be animals; in particular, human subjects can be treated.
Direct delivery of the compositions will generally be accomplished by injection, either subcutaneously, intraperitoneally, intravenously or intramuscularly or delivered to the interstitial space of a tissue. The compositions can also be administered into a lesion. Other modes of administration include oral and pulmonary administration, suppositories, and transdermal and transcutaneous applications, needles, and gene guns or hyposprays. Dosage treatment may be a single dose schedule or a multiple dose schedule.
Vaccines
Vaccines according to the invention may either be prophylactic (i.e., to prevent infection) or therapeutic (i.e., to treat disease after infection).
Such vaccines comprise immunizing antigen(s) or immunogen(s), immunogenic polypeptide, protein(s) or protein fragments, or nucleic acids (e.g., ribonucleic acid or deoxyribonucleic acid), usually in combination with “pharmaceutically acceptable carriers,” which include any carrier that does not itself induce the production of antibodies harmful to the individual receiving the composition. Suitable carriers are typically large, slowly metabolized macromolecules such as proteins, polysaccharides, polylactic acids, polyglycolic acids, polymeric amino acids, amino acid copolymers, lipid aggregates (such as oil droplets or liposomes), and inactive virus particles. Such carriers are well known to those of ordinary skill in the art. Additionally, these carriers may function as immunostimulating agents (“adjuvants”). Furthermore, the immunogen or antigen may be conjugated to a bacterial toxoid, such as a toxoid from diphtheria, tetanus, cholera, H. pylori, etc. pathogens.
Preferred adjuvants to enhance effectiveness of the composition include, but are not limited to: (1) aluminum salts (alum), such as aluminum hydroxide, aluminum phosphate, aluminum sulfate, etc; (2) oil-in-water emulsion formulations (with or without other specific immunostimulating agents such as muramyl peptides (see below) or bacterial cell wall components), such as for example (a) MF59 (PCT Publ. No. WO 90/14837), containing 5% Squalene, 0.5% TWEEN 80TM, and 0.5% SPAN 85TM (optionally containing various amounts of MTP-PE (see below), although not required) formulated into submicron particles using a microfluidizer such as Model 110Y microfluidizer (Microfluidics, Newton, Mass.), (b) SAF, containing 10% Squalane, 0.4% Tween 80, 5% PLURONICTM-blocked polymer L121, and thr-MDP (see below) either microfluidized into a submicron emulsion or vortexed to generate a larger particle size emulsion, and (c) RIBITM adjuvant system (RAS), (Ribi Immunochem, Hamilton, Mont.) containing 2% Squalene, 0.2% TWEEN 80TM, and one or more bacterial cell wall components from the group consisting of monophosphorylipid A (MPL), trehalose dimycolate (TDM), and cell wall skeleton (CWS), preferably MPL+CWS (DETOXTM); (3) saponin adjuvants, such as STIMULONTM (Cambridge Bioscience, Worcester, Mass.) may be used or particles generated therefrom such as ISCOMs (immunostimulating complexes); (4) Complete Freund's Adjuvant (CFA) and Incomplete Freund's Adjuvant (IFA); (5) cytokines, such as interleukins (e.g., IL-1, IL-2, IL-4, IL-5, IL-6, IL-7, IL-12, etc.), interferons (e.g., gamma interferon), macrophage colony stimulating factor (M-CSF), tumor necrosis factor (TNF), etc; and (6) other substances that act as immunostimulating agents to enhance the effectiveness of the composition. Alum and MF59 are preferred.
As mentioned above, muramyl peptides include, but are not limited to, N-acetyl-muramyl-L-threonyl-D-isoglutamine (thr-MDP), N-acetyl-normuramyl-L-alanyl-D-isoglutamine (nor-MDP), N-acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanine-2-(1′-2′-dipalmitoyl-sn-glycero-3-huydroxyphosphoryloxy)-ethylamine (MTP-PE), etc.
The vaccine compositions comprising immunogenic compositions (e.g., which may include the antigen, pharmaceutically acceptable carrier, and adjuvant) typically will contain diluents, such as water, saline, glycerol, ethanol, etc. Additionally, auxiliary substances, such as wetting or emulsifying agents, pH buffering substances, and the like, may be present in such vehicles. Alternatively, vaccine compositions comprising immunogenic compositions may comprise an antigen, polypeptide, protein, protein fragment or nucleic acid in a pharmaceutically acceptable carrier.
More specifically, vaccines comprising immunogenic compositions comprise an immunologically effective amount of the immunogenic polypeptides, as well as any other of the above-mentioned components, as needed. By “immunologically effective amount”, it is meant that the administration of that amount to an individual, either in a single dose or as part of a series, is effective for treatment or prevention. This amount varies depending upon the health and physical condition of the individual to be treated, the taxonomic group of individual to be treated (e.g., nonhuman primate, primate, etc.), the capacity of the individual's immune system to synthesize antibodies, the degree of protection desired, the formulation of the vaccine, the treating doctor's assessment of the medical situation, and other relevant factors. It is expected that the amount will fall in a relatively broad range that can be determined through routine trials.
Typically, the vaccine compositions or immunogenic compositions are prepared as injectables, either as liquid solutions or suspensions; solid forms suitable for solution in, or suspension in, liquid vehicles prior to injection may also be prepared. The preparation also may be emulsified or encapsulated in liposomes for enhanced adjuvant effect, as discussed above under pharmaceutically acceptable carriers.
The immunogenic compositions are conventionally administered parenterally, e.g., by injection, either subcutaneously or intramuscularly. Additional formulations suitable for other modes of administration include oral and pulmonary formulations, suppositories, and transdermal and transcutaneous applications. Dosage treatment may be a single dose schedule or a multiple dose schedule. The vaccine may be administered in conjunction with other immunoregulatory agents.
As an alternative to protein-based vaccines, DNA vaccination may be employed (e.g., Robinson & Torres (1997) Seminars in Immunology 9:271-283; Donnelly et al. (1997) Annu Rev Immunol 15:617-648).
Gene Delivery Vehicles
Gene therapy vehicles for delivery of constructs, including a coding sequence of a therapeutic of the invention, to be delivered to the mammal for expression in the mammal, can be administered either locally or systemically. These constructs can utilize viral or non-viral vector approaches in in vivo or ex vivo modality. Expression of such coding sequence can be induced using endogenous mammalian or heterologous promoters. Expression of the coding sequence in vivo can be either constitutive or regulated.
The invention includes gene delivery vehicles capable of expressing the contemplated nucleic acid sequences. The gene delivery vehicle is preferably a viral vector and, more preferably, a retroviral, adenoviral, adeno-associated viral (AAV), herpes viral, or alphavirus vector. The viral vector can also be an astrovirus, coronavirus, orthomyxovirus, papovavirus, paramyxovirus, parvovirus, picornavirus, poxvirus, or togavirus viral vector. See generally, Jolly (1994) Cancer Gene Therapy 1:51-64; Kimura (1994) Human Gene Therapy 5:845-852; Connelly (1995) Human Gene Therapy 6:185-193; and Kaplitt (1994) Nature Genetics 6:148-153.
Retroviral vectors are well known in the art, including B, C and D type retroviruses, xenotropic retroviruses (for example, NZB-X1, NZB-X2 and NZB9-1 (see O'Neill (1985) J. Virol. 53:160) polytropic retroviruses e.g., MCF and MCF-MLV (see Kelly (1983) J. Virol. 45:291), spumaviruses and lentiviruses. See RNA Tumor Viruses, Second Edition, Cold Spring Harbor Laboratory, 1985.
Portions of the retroviral gene therapy vector may be derived from different retroviruses. For example, retrovector LTRs may be derived from a Murine Sarcoma Virus, a tRNA binding site from a Rous Sarcoma Virus, a packaging signal from a Murine Leukemia Virus, and an origin of second strand synthesis from an Avian Leukosis Virus.
These recombinant retroviral vectors may be used to generate transduction competent retroviral vector particles by introducing them into appropriate packaging cell lines (see U.S. Pat. No. 5,591,624). Retrovirus vectors can be constructed for site-specific integration into host cell DNA by incorporation of a chimeric integrase enzyme into the retroviral particle (see WO96/37626). It is preferable that the recombinant viral vector is a replication defective recombinant virus.
Packaging cell lines suitable for use with the above-described retrovirus vectors are well known in the art, are readily prepared (see WO95/30763 and WO92/05266), and can be used to create producer cell lines (also termed vector cell lines or “VCLs”) for the production of recombinant vector particles. Preferably, the packaging cell lines are made from human parent cells (e.g., HT1080 cells) or mink parent cell lines, which eliminates inactivation in human serum.
Preferred retroviruses for the construction of retroviral gene therapy vectors include Avian Leukosis Virus, Bovine Leukemia Virus, Murine Leukemia Virus, Mink-Cell Focus-Inducing Virus, Murine Sarcoma Virus, Reticuloendotheliosis Virus and Rous Sarcoma Virus. Particularly preferred Murine Leukemia Viruses include 4070A and 1504A (Hartley and Rowe (1976) J Virol 19:19-25), Abelson (ATCC No. VR-999), Friend (ATCC No. VR-245), Graffi, Gross (ATCC Nol VR-590), Kirsten, Harvey Sarcoma Virus and Rauscher (ATCC No. VR-998) and Moloney Murine Leukemia Virus (ATCC No. VR-190). Such retroviruses may be obtained from depositories or collections such as the American Type Culture Collection (“ATCC”) or isolated from known sources using commonly available techniques.
Exemplary known retroviral gene therapy vectors employable in this invention include those described in patent applications GB2200651, EP0415731, EP0345242, EP0334301, WO89/02468; WO89/05349, WO89/09271, WO90/02806, WO90/07936, WO94/03622, WO93/25698, WO93/25234, WO93/11230, WO93/10218, WO91/02805, WO91/02825, WO95/07994, U.S. Pat. No. 5,219,740, U.S. Pat. No. 4,405,712, U.S. Pat. No. 4,861,719, U.S. Pat. No. 4,980,289, U.S. Pat. No. 4,777,127, U.S. Pat. No. 5,591,624. See also Vile (1993) Cancer Res 53:3860-3864; Vile (1993) Cancer Res 53:962-967; Ram (1993) Cancer Res 53 (1993) 83-88; Takamiya (1992) J Neurosci Res 33:493-503; Baba (1993) J Neurosurg 79:729-735; Mann (1983) Cell 33:153; Cane (1984) Proc Natl Acad Sci 81:6349; and Miller (1990) Human Gene Therapy 1.
Human adenoviral gene therapy vectors are also known in the art and employable in this invention. See, for example, Berkner (1988) Biotechniques 6:616 and Rosenfeld (1991) Science 252:431, and WO93/07283, WO93/06223, and WO93/07282. Exemplary known adenoviral gene therapy vectors employable in this invention include those described in the above referenced documents and in WO94/12649, WO93/03769, WO93/19191, WO94/28938, WO95/11984, WO95/00655, WO95/27071, WO95/29993, WO95/34671, WO96/05320, WO94/08026, WO94/11506, WO93/06223, WO94/24299, WO95/14102, WO95/24297, WO95/02697, WO94/28152, WO94/24299, WO95/09241, WO95/25807, WO95/05835, WO94/18922 and WO95/09654. Alternatively, administration of DNA linked to killed adenovirus as described in Curiel (1992) Hum. Gene Ther. 3:147-154 may be employed. The gene delivery vehicles of the invention also include adenovirus associated virus (AAV) vectors. Leading and preferred examples of such vectors for use in this invention are the AAV-2 based vectors disclosed in Srivastava, WO93/09239. Most preferred AAV vectors comprise the two AAV inverted terminal repeats in which the native D-sequences are modified by substitution of nucleotides, such that at least 5 native nucleotides and up to 18 native nucleotides, preferably at least 10 native nucleotides up to 18 native nucleotides, most preferably 10 native nucleotides are retained and the remaining nucleotides of the D-sequence are deleted or replaced with non-native nucleotides. The native D-sequences of the AAV inverted terminal repeats are sequences of 20 consecutive nucleotides in each AAV inverted terminal repeat (i.e., there is one sequence at each end) which are not involved in HP formation. The non-native replacement nucleotide may be any nucleotide other than the nucleotide found in the native D-sequence in the same position. Other employable exemplary AAV vectors are pWP-19, pWN-1, both of which are disclosed in Nahreini (1993) Gene 124:257-262. Another example of such an AAV vector is psub201 (see Samulski (1987) J. Virol. 61:3096). Another exemplary AAV vector is the Double-D ITR vector. Construction of the Double-D ITR vector is disclosed in U.S. Pat. No. 5,478,745. Still other vectors are those disclosed in Carter U.S. Pat. No. 4,797,368 and Muzyczka U.S. Pat. No. 5,139,941, Chartejee U.S. Pat. No. 5,474,935, and Kotin WO94/288157. Yet a further example of an AAV vector employable in this invention is SSV9AFABTKneo, which contains the AFP enhancer and albumin promoter and directs expression predominantly in the liver. Its structure and construction are disclosed in Su (1996) Human Gene Therapy 7:463-470. Additional AAV gene therapy vectors are described in U.S. Pat. No. 5,354,678, U.S. Pat. No. 5,173,414, U.S. Pat. No. 5,139,941, and U.S. Pat. No. 5,252,479.
The gene therapy vectors comprising sequences of the invention also include herpes vectors. Leading and preferred examples are herpes simplex virus vectors containing a sequence encoding a thymidine kinase polypeptide such as those disclosed in U.S. Pat. No. 5,288,641 and EP0176170 (Roizman). Additional exemplary herpes simplex virus vectors include HFEM/ICP6-LacZ disclosed in WO95/04139 (Wistar Institute), pHSVlac described in Geller (1988) Science 241:1667-1669 and in WO90/09441 and WO92/07945, HSV Us3::pgC-lacZ described in Fink (1992) Human Gene Therapy 3:11-19 and HSV 7134, 2 RH 105 and GAL4 described in EP 0453242 (Breakefield), and those deposited with the ATCC as accession numbers ATCC VR-977 and ATCC VR-260.
Also contemplated are alpha virus gene therapy vectors that can be employed in this invention. Preferred alpha virus vectors are Sindbis viruses vectors. Togaviruses, Semliki Forest virus (ATCC VR-67; ATCC VR-1247), Middleberg virus (ATCC VR-370), Ross River virus (ATCC VR-373; ATCC VR-1246), Venezuelan equine encephalitis virus (ATCC VR923; ATCC VR-1250; ATCC VR-1249; ATCC VR-532), and those described in U.S. Pat. Nos. 5,091,309, 5,217,879, and WO92/10578. More particularly, those alpha virus vectors described in U.S. Ser. No. 08/405,627, filed Mar. 15, 1995, WO94/21792, WO92/10578, WO95/07994, U.S. Pat. No. 5,091,309 and U.S. Pat. No. 5,217,879 are employable. Such alpha viruses may be obtained from depositories or collections such as the ATCC or isolated from known sources using commonly available techniques. Preferably, alphavirus vectors with reduced cytotoxicity are used (see U.S. Ser. No. 08/679,640).
DNA vector systems such as eukarytic layered expression systems are also useful for expressing the nucleic acids of the invention. See WO95/07994 for a detailed description of eukaryotic layered expression systems. Preferably, the eukaryotic layered expression systems of the invention are derived from alphavirus vectors and most preferably from Sindbis viral vectors.
Other viral vectors suitable for use in the present invention include those derived from poliovirus, for example ATCC VR-58 and those described in Evans, Nature 339 (1989) 385 and Sabin (1973) J. Biol. Standardization 1:115; rhinovirus, for example ATCC VR-1110 and those described in Arnold (1990) J Cell Biochem L401; pox viruses such as canary pox virus or vaccinia virus, for example ATCC VR-111 and ATCC VR-2010 and those described in Fisher-Hoch (1989) Proc Natl Acad Sci 86:317; Flexner (1989) Ann NY Acad Sci 569:86, Flexner (1990) Vaccine 8:17; in U.S. Pat. No. 4,603,112 and U.S. Pat. No. 4,769,330 and WO89/01973; SV40 virus, for example ATCC VR-305 and those described in Mulligan (1979) Nature 277:108 and Madzak (1992) J Gen Virol 73:1533; influenza virus, for example ATCC VR-797 and recombinant influenza viruses made employing reverse genetics techniques as described in U.S. Pat. No. 5,166,057 and in Enami (1990) Proc Natl Acad Sci 87:3802-3805; Enami & Palese (1991) J Virol 65:2711-2713 and Luytjes (1989) Cell 59:110, (see also McMichael (1983) NEJ Med 309:13, and Yap (1978) Nature 273:238 and Nature (1979) 277:108); human immunodeficiency virus as described in EP-0386882 and in Buchschacher (1992) J. Virol. 66:2731; measles virus, for example ATCC VR-67 and VR-1247 and those described in EP-0440219; Aura virus, for example ATCC VR-368; Bebaru virus, for example ATCC VR-600 and ATCC VR-1240; Cabassou virus, for example ATCC VR-922; Chikungunya virus, for example ATCC VR-64 and ATCC VR-1241; Fort Morgan Virus, for example ATCC VR-924; Getah virus, for example ATCC VR-369 and ATCC VR-1243; Kyzylagach virus, for example ATCC VR-927; Mayaro virus, for example ATCC VR-66; Mucambo virus, for example ATCC VR-580 and ATCC VR-1244; Ndumu virus, for example ATCC VR-371; Pixuna virus, for example ATCC VR-372 and ATCC VR-1245; Tonate virus, for example ATCC VR-925; Triniti virus, for example ATCC VR-469; Una virus, for example ATCC VR-374; Whataroa virus, for example ATCC VR-926; Y-62-33 virus, for example ATCC VR-375; O'Nyong virus, Eastern encephalitis virus, for example ATCC VR-65 and ATCC VR-1242; Western encephalitis virus, for example ATCC VR-70, ATCC VR-1251, ATCC VR-622 and ATCC VR-1252; and coronavirus, for example ATCC VR-740 and those described in Hamre (1966) Proc Soc Exp Biol Med 121:190.
Delivery of the compositions of this invention into cells is not limited to the above mentioned viral vectors. Other delivery methods and media may be employed such as, for example, nucleic acid expression vectors, polycationic condensed DNA linked or unlinked to killed adenovirus alone, for example see U.S. Ser. No. 08/366,787, filed Dec. 30, 1994 and Curiel (1992) Hum Gene Ther 3:147-154 ligand linked DNA, for example see Wu (1989) J Biol Chem 264:16985-16987, eucaryotic cell delivery vehicles cells, for example see U.S. Ser. No. 08/240,030, filed May 9, 1994, and U.S. Ser. No. 08/404,796, deposition of photopolymerized hydrogel materials, hand-held gene transfer particle gun, as described in U.S. Pat. No. 5,149,655, ionizing radiation as described in U.S. Pat. No. 5,206,152 and in WO92/11033, nucleic charge neutralization or fusion with cell membranes. Additional approaches are described in Philip (1994) Mol Cell Biol 14:2411-2418 and in Woffendin (1994) Proc Natl Acad Sci 91:1581-1585.
Particle mediated gene transfer may be employed, for example see U.S. Ser. No. 60/023,867. Briefly, the sequence can be inserted into conventional vectors that contain conventional control sequences for high level expression, and then incubated with synthetic gene transfer molecules such as polymeric DNA-binding cations like polylysine, protamine, and albumin, linked to cell targeting ligands such as asialoorosomucoid, as described in Wu & Wu (1987) J. Biol. Chem. 262:4429-4432, insulin as described in Hucked (1990) Biochem Pharmacol 40:253-263, galactose as described in Plank (1992) Bioconjugate Chem 3:533-539, lactose or transferrin.
Naked DNA may also be employed to transform a host cell. Exemplary naked DNA introduction methods are described in WO 90/11092 and U.S. Pat. No. 5,580,859. Uptake efficiency may be improved using biodegradable latex beads. DNA coated latex beads are efficiently transported into cells after endocytosis initiation by the beads. The method may be improved further by treatment of the beads to increase hydrophobicity and thereby facilitate disruption of the endosome and release of the DNA into the cytoplasm.
Liposomes that can act as gene delivery vehicles are described in U.S. Pat. No. 5,422,120, WO95/13796, WO94/23697, WO91/14445 and EP-524,968. As described in U.S. Ser. No. 60/023,867, on non-viral delivery, the nucleic acid sequences encoding a polypeptide can be inserted into conventional vectors that contain conventional control sequences for high level expression, and then be incubated with synthetic gene transfer molecules such as polymeric DNA-binding cations like polylysine, protamine, and albumin, linked to cell targeting ligands such as asialoorosomucoid, insulin, galactose, lactose, or transferrin. Other delivery systems include the use of liposomes to encapsulate DNA comprising the gene under the control of a variety of tissue-specific or ubiquitously-active promoters. Further non-viral delivery suitable for use includes mechanical delivery systems such as the approach described in Woffendin et al (1994) Proc. Natl. Acad. Sci. USA 91(24):11581-11585. Moreover, the coding sequence and the product of expression of such can be delivered through deposition of photopolymerized hydrogel materials. Other conventional methods for gene delivery that can be used for delivery of the coding sequence include, for example, use of hand-held gene transfer particle gun, as described in U.S. Pat. No. 5,149,655; use of ionizing radiation for activating transferred gene, as described in U.S. Pat. No. 5,206,152 and WO92/11033.
Exemplary liposome and polycationic gene delivery vehicles are those described in U.S. Pat. Nos. 5,422,120 and 4,762,915; in WO 95/13796; WO94/23697; and WO91/14445; in EP-0524968; and in Stryer, Biochemistry, pages 236-240 (1975) W.H. Freeman, San Francisco; Szoka (1980) Biochem Biophys Acta 600:1; Bayer (1979) Biochem Biophys Acta 550:464; Rivnay (1987) Meth Enzymol 149:119; Wang (1987) Proc Natl Acad Sci 84:7851; Plant (1989) Anal Biochem 176:420.
A polynucleotide composition can comprises therapeutically effective amount of a gene therapy vehicle, as the term is defined above. For purposes of the present invention, an effective dose will be from about 0.01 mg/kg to 50 mg/kg or 0.05 mg/kg to about 10 mg/kg of the DNA constructs in the individual to which it is administered.
Delivery Methods
Once formulated, the polynucleotide compositions of the invention can be administered (1) directly to the subject; (2) delivered ex vivo, to cells derived from the subject; or (3) in vitro for expression of recombinant proteins. The subjects to be treated can be mammals or birds. Also, human subjects can be treated.
Direct delivery of the compositions will generally be accomplished by injection, either subcutaneously, intraperitoneally, intravenously or intramuscularly or delivered to the interstitial space of a tissue. The compositions can also be administered into a tumor or lesion. Other modes of administration include oral and pulmonary administration, suppositories, and transdermal applications, needles, and gene guns or hyposprays. Dosage treatment may be a single dose schedule or a multiple dose schedule.
Methods for the ex vivo delivery and reimplantation of transformed cells into a subject are known in the art and described in eg. WO93/14778. Examples of cells useful in ex vivo applications include, for example, stem cells, particularly hematopoetic, lymph cells, macrophages, dendritic cells, or tumor cells.
Generally, delivery of nucleic acids for both ex vivo and in vitro applications can be accomplished by the following procedures, for example, dextran-mediated transfection, calcium phosphate precipitation, polybrene mediated transfection, protoplast fusion, electroporation, encapsulation of the polynucleotide(s) in liposomes, and direct microinjection of the DNA into nuclei, all well known in the art.
Polynucleotide and Polypeptide Pharmaceutical Compositions
In addition to the pharmaceutically acceptable carriers and salts described above, the following additional agents can be used with polynucleotide and/or polypeptide compositions.
A. Polypeptides
One example are polypeptides which include, without limitation: asioloorosomucoid (ASOR); transferrin; asialoglycoproteins; antibodies; antibody fragments; ferritin; interleukins; interferons, granulocyte, macrophage colony stimulating factor (GM-CSF), granulocyte colony stimulating factor (G-CSF), macrophage colony stimulating factor (M-CSF), stem cell factor and erythropoietin. Viral antigens, such as envelope proteins, can also be used. Also, proteins from other invasive organisms, such as the 17 amino acid peptide from the circumsporozoite protein of plasmodium falciparum known as RII.
B. Hormones, Vitamins, Etc.
Other groups that can be included are, for example: hormones, steroids, androgens, estrogens, thyroid hormone, or vitamins, folic acid.
C. Polyalkylenes, Polysaccharides, etc.
Also, polyalkylene glycol can be included with the desired polynucleotides or polypeptides. In a preferred embodiment, the polyalkylene glycol is polyethlylene glycol. In addition, mono-, di-, or polysaccarides can be included. In a preferred embodiment of this aspect, the polysaccharide is dextran or DEAE-dextran. Also, chitosan and poly(lactide-co-glycolide)
D. Lipids, and Liposomes
The desired polynucleotide or polypeptide can also be encapsulated in lipids or packaged in liposomes prior to delivery to the subject or to cells derived therefrom.
Lipid encapsulation is generally accomplished using liposomes which are able to stably bind or entrap and retain nucleic acid. The ratio of condensed polynucleotide or polypeptide to lipid preparation can vary but will generally be around 1:1 (mg DNA:micromoles lipid), or more of lipid. For a review of the use of liposomes as carriers for delivery of nucleic acids, see, Hug and Sleight (1991) Biochim. Biophys. Acta. 1097:1-17; Straubinger (1983) Meth. Enzymol. 101:512-527.
Liposomal preparations for use in the present invention include cationic (positively charged), anionic (negatively charged) and neutral preparations. Cationic liposomes have been shown to mediate intracellular delivery of plasmid DNA (Felgner (1987) Proc. Natl. Acad. Sci. USA 84:7413-7416); mRNA (Malone (1989) Proc. Natl. Acad. Sci. USA 86:6077-6081); and purified transcription factors (Debs (1990) J. Biol. Chem. 265:10189-10192), in functional form.
Cationic liposomes are readily available. For example, N[1-2,3-dioleyloxy)propyl]-N,N,N-triethylammonium (DOTMA) liposomes are available under the trademark Lipofectin, from GIBCO BRL, Grand Island, N.Y. (See, also, Felgner supra). Other commercially available liposomes include transfectace (DDAB/DOPE) and DOTAP/DOPE (Boerhinger). Other cationic liposomes can be prepared from readily available materials using techniques well known in the art. See, eg. Szoka (1978) Proc. Natl. Acad. Sci. USA 75:4194-4198; WO90/11092 for a description of the synthesis of DOTAP (1,2-bis(oleoyloxy)-3-(trimethylammonio)propane) liposomes.
Similarly, anionic and neutral liposomes are readily available, such as from Avanti Polar Lipids (Birmingham, Ala.), or can be easily prepared using readily available materials. Such materials include phosphatidyl choline, cholesterol, phosphatidyl ethanolamine, dioleoylphosphatidyl choline (DOPC), dioleoylphosphatidyl glycerol (DOPG), dioleoylphoshatidyl ethanolamine (DOPE), among others. These materials can also be mixed with the DOTMA and DOTAP starting materials in appropriate ratios. Methods for making liposomes using these materials are well known in the art.
The liposomes can comprise multilammelar vesicles (MLVs), small unilamellar vesicles (SUVs), or large unilamellar vesicles (LUVs). The various liposome-nucleic acid complexes are prepared using methods known in the art. See eg. Straubinger (1983) Meth. Immunol. 101:512-527; Szoka (1978) Proc. Natl. Acad. Sci. USA 75:4194-4198; Papahadjopoulos (1975) Biochim. Biophys. Acta 394:483; Wilson (1979) Cell 17:77); Deamer & Bangham (1976) Biochim. Biophys. Acta 443:629; Ostro (1977) Biochem. Biophys. Res. Commun. 76:836; Fraley (1979) Proc. Natl. Acad. Sci. USA 76:3348); Enoch & Strittmatter (1979) Proc. Natl. Acad. Sci. USA 76:145; Fraley (1980) J. Biol. Chem. (1980) 255:10431; Szoka & Papahadjopoulos (1978) Proc. Natl. Acad. Sci. USA 75:145; and Schaefer-Ridder (1982) Science 215:166.
E. Lipoproteins
In addition, lipoproteins can be included with the polynucleotide or polypeptide to be delivered. Examples of lipoproteins to be utilized include: chylomicrons, HDL, IDL, LDL, and VLDL. Mutants, fragments, or fusions of these proteins can also be used. Also, modifications of naturally occurring lipoproteins can be used, such as acetylated LDL. These lipoproteins can target the delivery of polynucleotides to cells expressing lipoprotein receptors. Preferably, if lipoproteins are including with the polynucleotide to be delivered, no other targeting ligand is included in the composition.
Naturally occurring lipoproteins comprise a lipid and a protein portion. The protein portion are known as apoproteins. At the present, apoproteins A, B, C, D, and E have been isolated and identified. At least two of these contain several proteins, designated by Roman numerals, AI, AII, AIV; CI, CII, CIII.
A lipoprotein can comprise more than one apoprotein. For example, naturally occurring chylomicrons comprises of A, B, C, and E, over time these lipoproteins lose A and acquire C and E apoproteins. VLDL comprises A, B, C, and E apoproteins, LDL comprises apoprotein B; and HDL comprises apoproteins A, C, and E.
The amino acid of these apoproteins are known and are described in, for example, Breslow (1985) Annu Rev. Biochem 54:699; Law (1986) Adv. Exp Med. Biol. 151:162; Chen (1986) J Biol Chem 261:12918; Kane (1980) Proc Natl Acad Sci USA 77:2465; and Utermann (1984) Hum Genet. 65:232.
Lipoproteins contain a variety of lipids including, triglycerides, cholesterol (free and esters), and phopholipids. The composition of the lipids varies in naturally occurring lipoproteins. For example, chylomicrons comprise mainly triglycerides. A more detailed description of the lipid content of naturally occurring lipoproteins can be found, for example, in Meth. Enzymol. 128 (1986). The composition of the lipids are chosen to aid in conformation of the apoprotein for receptor binding activity. The composition of lipids can also be chosen to facilitate hydrophobic interaction and association with the polynucleotide binding molecule.
Naturally occurring lipoproteins can be isolated from serum by ultracentrifugation, for instance. Such methods are described in Meth. Enzymol. (supra); Pitas (1980) J. Biochem. 255:5454-5460 and Mahey (1979) J. Clin. Invest 64:743-750.
Lipoproteins can also be produced by in vitro or recombinant methods by expression of the apoprotein genes in a desired host cell. See, for example, Atkinson (1986) Annu Rev Biophys Chem 15:403 and Radding (1958) Biochim Biophys Acta 30: 443.
Lipoproteins can also be purchased from commercial suppliers, such as Biomedical Techniologies, Inc., Stoughton, Mass., USA.
Further description of lipoproteins can be found in Zuckermann et al., PCT. Appln. No. US97/14465.
F. Polycationic Agents
Polycationic agents can be included, with or without lipoprotein, in a composition with the desired polynucleotide or polypeptide to be delivered.
Polycationic agents, typically, exhibit a net positive charge at physiological relevant pH and are capable of neutralizing the electrical charge of nucleic acids to facilitate delivery to a desired location. These agents have both in vitro, ex vivo, and in vivo applications. Polycationic agents can be used to deliver nucleic acids to a living subject either intramuscularly, subcutaneously, etc.
The following are examples of useful polypeptides as polycationic agents: polylysine, polyarginine, polyornithine, and protamine. Other examples include histones, protamines, human serum albumin, DNA binding proteins, non-histone chromosomal proteins, coat proteins from DNA viruses, such as (X174, transcriptional factors also contain domains that bind DNA and therefore may be useful as nucleic aid condensing agents. Briefly, transcriptional factors such as C/CEBP, c-jun, c-fos, AP-1, AP-2, AP-3, CPF, Prot-1, Sp-1, Oct-1, Oct-2, CREP, and TFIID contain basic domains that bind DNA sequences.
Organic polycationic agents include: spermine, spermidine, and purtrescine.
The dimensions and of the physical properties of a polycationic agent can be extrapolated from the list above, to construct other polypeptide polycationic agents or to produce synthetic polycationic agents.
Synthetic Polycationic Agents
Synthetic polycationic agents which are useful include, for example, DEAE-dextran, polybrene. LIPOFECTINTM, and LIPOFECTAMINETM are monomers that form polycationic complexes when combined with polynucleotides or polypeptides.
Immunodiagnostic Assays
Neis serial antigens of the invention can be used in immunoassays to detect antibody levels (or, conversely, anti-Neisserial antibodies can be used to detect antigen levels). Immunoassays based on well defined, recombinant antigens can be developed to replace invasive diagnostics methods. Antibodies to Neis serial proteins within biological samples, including for example, blood or serum samples, can be detected. Design of the immunoassays is subject to a great deal of variation, and a variety of these are known in the art. Protocols for the immunoassay may be based, for example, upon competition, or direct reaction, or sandwich type assays. Protocols may also, for example, use solid supports, or may be by immunoprecipitation. Most assays involve the use of labeled antibody or polypeptide; the labels may be, for example, fluorescent, chemiluminescent, radioactive, or dye molecules. Assays which amplify the signals from the probe are also known; examples of which are assays which utilize biotin and avidin, and enzyme-labeled and mediated immunoassays, such as ELISA assays.
Kits suitable for immunodiagnosis and containing the appropriate labeled reagents are constructed by packaging the appropriate materials, including the compositions of the invention, in suitable containers, along with the remaining reagents and materials (for example, suitable buffers, salt solutions, etc.) required for the conduct of the assay, as well as suitable set of assay instructions.
Nucleic Acid Hybridisation
“Hybridization” refers to the association of two nucleic acid sequences to one another by hydrogen bonding. Typically, one sequence will be fixed to a solid support and the other will be free in solution. Then, the two sequences will be placed in contact with one another under conditions that favor hydrogen bonding. Factors that affect this bonding include: the type and volume of solvent; reaction temperature; time of hybridization; agitation; agents to block the non-specific attachment of the liquid phase sequence to the solid support (Denhardt's reagent or BLOTTO); concentration of the sequences; use of compounds to increase the rate of association of sequences (dextran sulfate or polyethylene glycol); and the stringency of the washing conditions following hybridization. See Sambrook et al. [supra] Volume 2, chapter 9, pages 9.47 to 9.57.
“Stringency” refers to conditions in a hybridization reaction that favor association of very similar sequences over sequences that differ. For example, the combination of temperature and salt concentration should be chosen that is approximately 120 to 200° C. below the calculated Tm of the hybrid under study. The temperature and salt conditions can often be determined empirically in preliminary experiments in which samples of genomic DNA immobilized on filters are hybridized to the sequence of interest and then washed under conditions of different stringencies. See Sambrook et al. at page 9.50.
Variables to consider when performing, for example, a Southern blot are (1) the complexity of the DNA being blotted and (2) the homology between the probe and the sequences being detected. The total amount of the fragment(s) to be studied can vary a magnitude of 10, from 0.1 to 1 μg for a plasmid or phage digest to 10−9 to 10−8 g for a single copy gene in a highly complex eukaryotic genome. For lower complexity polynucleotides, substantially shorter blotting, hybridization, and exposure times, a smaller amount of starting polynucleotides, and lower specific activity of probes can be used. For example, a single-copy yeast gene can be detected with an exposure time of only 1 hour starting with 1 μg of yeast DNA, blotting for two hours, and hybridizing for 4-8 hours with a probe of 108 cpm/μg. For a single-copy mammalian gene a conservative approach would start with 10 μg of DNA, blot overnight, and hybridize overnight in the presence of 10% dextran sulfate using a probe of greater than 108 cpm/μg, resulting in an exposure time of  ̃24 hours.
Several factors can affect the melting temperature (Tm) of a DNA-DNA hybrid between the probe and the fragment of interest, and consequently, the appropriate conditions for hybridization and washing. In many cases the probe is not 100% homologous to the fragment. Other commonly encountered variables include the length and total G+C content of the hybridizing sequences and the ionic strength and formamide content of the hybridization buffer. The effects of all of these factors can be approximated by a single equation:

Tm=81+16.6(log10Ci)+0.4[% (G+C)]-0.6(% formamide)−600/n−1.5(% mismatch).

where Ci is the salt concentration (monovalent ions) and n is the length of the hybrid in base pairs (slightly modified from Meinkoth & Wahl (1984) Anal. Biochem. 138: 267-284).
In designing a hybridization experiment, some factors affecting nucleic acid hybridization can be conveniently altered. The temperature of the hybridization and washes and the salt concentration during the washes are the simplest to adjust. As the temperature of the hybridization increases (ie. stringency), it becomes less likely for hybridization to occur between strands that are nonhomologous, and as a result, background decreases. If the radiolabeled probe is not completely homologous with the immobilized fragment (as is frequently the case in gene family and interspecies hybridization experiments), the hybridization temperature must be reduced, and background will increase. The temperature of the washes affects the intensity of the hybridizing band and the degree of background in a similar manner. The stringency of the washes is also increased with decreasing salt concentrations.
In general, convenient hybridization temperatures in the presence of 50% formamide are 42° C. for a probe with is 95% to 100% homologous to the target fragment, 37° C. for 90% to 95% homology, and 32° C. for 85% to 90% homology. For lower homologies, formamide content should be lowered and temperature adjusted accordingly, using the equation above. If the homology between the probe and the target fragment are not known, the simplest approach is to start with both hybridization and wash conditions which are nonstringent. If non-specific bands or high background are observed after autoradiography, the filter can be washed at high stringency and reexposed. If the time required for exposure makes this approach impractical, several hybridization and/or washing stringencies should be tested in parallel.
Nucleic Acid Probe Assays
Methods such as PCR, branched DNA probe assays, or blotting techniques utilizing nucleic acid probes according to the invention can determine the presence of cDNA or mRNA. A probe is said to “hybridize” with a sequence of the invention if it can form a duplex or double stranded complex, which is stable enough to be detected.
The nucleic acid probes will hybridize to the Neis serial nucleotide sequences of the invention (including both sense and antisense strands). Though many different nucleotide sequences will encode the amino acid sequence, the native Neis serial sequence is preferred because it is the actual sequence present in cells. mRNA represents a coding sequence and so a probe should be complementary to the coding sequence; single-stranded cDNA is complementary to mRNA, and so a cDNA probe should be complementary to the non-coding sequence.
The probe sequence need not be identical to the Neisserial sequence (or its complement)—some variation in the sequence and length can lead to increased assay sensitivity if the nucleic acid probe can form a duplex with target nucleotides, which can be detected. Also, the nucleic acid probe can include additional nucleotides to stabilize the formed duplex. Additional Neisserial sequence may also be helpful as a label to detect the formed duplex. For example, a non-complementary nucleotide sequence may be attached to the 5′ end of the probe, with the remainder of the probe sequence being complementary to a Neisserial sequence. Alternatively, non-complementary bases or longer sequences can be interspersed into the probe, provided that the probe sequence has sufficient complementarity with the a Neis serial sequence in order to hybridize therewith and thereby form a duplex which can be detected.
The exact length and sequence of the probe will depend on the hybridization conditions, such as temperature, salt condition and the like. For example, for diagnostic applications, depending on the complexity of the analyte sequence, the nucleic acid probe typically contains at least 10-20 nucleotides, preferably 15-25, and more preferably at least 30 nucleotides, although it may be shorter than this. Short primers generally require cooler temperatures to form sufficiently stable hybrid complexes with the template.
Probes may be produced by synthetic procedures, such as the triester method of Matteucci et al. [J. Am. Chem. Soc. (1981) 103:3185], or according to Urdea et al. [Proc. Natl. Acad. Sci. USA (1983) 80: 7461], or using commercially available automated oligonucleotide synthesizers.
The chemical nature of the probe can be selected according to preference. For certain applications, DNA or RNA are appropriate. For other applications, modifications may be incorporated eg. backbone modifications, such as phosphorothioates or methylphosphonates, can be used to increase in vivo half-life, alter RNA affinity, increase nuclease resistance etc. [eg. see Agrawal & Iyer (1995) Curr Opin Biotechnol 6:12-19; Agrawal (1996) TIBTECH 14:376-387]; analogues such as peptide nucleic acids may also be used [eg. see Corey (1997) TIBTECH 15:224-229; Buchardt et al. (1993) TIBTECH 11:384-386].
One example of a nucleotide hybridization assay is described by Urdea et al. in international patent application WO92/02526 [see also U.S. Pat. No. 5,124,246].
Alternatively, the polymerase chain reaction (PCR) is another well-known means for detecting small amounts of target nucleic acids. The assay is described in: Mullis et al. [Meth. Enzymol. (1987) 155: 335-350]; U.S. Pat. No. 4,683,195; and U.S. Pat. No. 4,683,202. Two “primer” nucleotides hybridize with the target nucleic acids and are used to prime the reaction. The primers can comprise sequence that does not hybridize to the sequence of the amplification target (or its complement) to aid with duplex stability or, for example, to incorporate a convenient restriction site. Typically, such sequence will flank the desired Neisserial sequence.
A thermostable polymerase creates copies of target nucleic acids from the primers using the original target nucleic acids as a template. After a threshold amount of target nucleic acids are generated by the polymerase, they can be detected by more traditional methods, such as Southern blots. When using the Southern blot method, the labelled probe will hybridize to the Neisserial sequence (or its complement).
Also, mRNA or cDNA can be detected by traditional blotting techniques described in Sambrook et al [supra]. mRNA, or cDNA generated from mRNA using a polymerase enzyme, can be purified and separated using gel electrophoresis. The nucleic acids on the gel are then blotted onto a solid support, such as nitrocellulose. The solid support is exposed to a labelled probe and then washed to remove any unhybridized probe. Next, the duplexes containing the labeled probe are detected. Typically, the probe is labelled with a radioactive moiety.
EXAMPLES
The examples describe nucleic acid sequences which have been identified in N. meningitidis, and N. gonorrhoeae along with their respective and putative translation products. Not all of the nucleic acid sequences are complete ie. they encode less than the full-length wild-type protein.
The examples are generally in the following format:

    
    
        a nucleotide sequence which has been identified in N. meningitidis 
        the putative translation product of said N. meningitidis sequence
        a computer analysis of said translation product based on database comparisons
        a corresponding nucleotide sequence identified from N. gonorrhoeae 
        the putative translation product of said N. gonorrhoeae sequence
        a comparison of the percentage of identity between the translation product of the N. meningitidis sequence and the N. gonorrhoeae sequence
        a description of the characteristics of the protein which indicates that it might be suitably antigenic or immunogenic.
    
    


Sequence comparisons were performed at NCBI (ncbi.nlm.nih.gov) using the algorithms BLAST, BLAST2, BLASTn, BLASTp, tBLASTn, BLASTx, & tBLASTx [eg. see also Altschul et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Research 25:2289-3402]. Searches were performed against the following databases: non-redundant GenBank+EMBL+DDBJ+PDB sequences and non-redundant GenBank CDS translations+PDB+Swis sProt+SPupdate+PIR sequences.
Dots within nucleotide sequences represent nucleotides which have been arbitrarily introduced in order to maintain a reading frame. In the same way, double-underlined nucleotides were removed. Lower case letters represent ambiguities which arose during alignment of independent sequencing reactions (some of the nucleotide sequences in the examples are derived from combining the results of two or more experiments).
Nucleotide sequences were scanned in all six reading frames to predict the presence of hydrophobic domains using an algorithm based on the statistical studies of Esposti et al. [Critical evaluation of the hydropathy of membrane proteins (1990) Eur J Biochem 190:207-219]. These domains represent potential transmembrane regions or hydrophobic leader sequences.
Open reading frames were predicted from fragmented nucleotide sequences using the program ORFFINDER (NCBI).
Underlined amino acid sequences indicate possible transmembrane domains or leader sequences in the ORFs, as predicted by the PSORT algorithm (psort.nibb.ac.jp). Functional domains were also predicted using the MOTIFS program (GCG Wisconsin & PROSITE).
For each of the following examples: based on the presence of a putative leader sequence and/or several putative transmembrane domains (single-underlined) in the gonococcal protein, it is predicted that the proteins from N. meningitidis and N. gonorrhoeae, and their respective epitopes, could be useful antigens or immunogenic compositions for vaccines or diagnostics.
The standard techniques and procedures which may be employed in order to perform the invention (e.g. to utilize the disclosed sequences for vaccination or diagnostic purposes) were summarized above. This summary is not a limitation on the invention but, rather, gives examples that may be used, but are not required.
In particular, the following methods were used to express, purify and biochemically characterize the proteins of the invention.
Chromosomal DNA Preparation
N. meningitidis strain 2996 was grown to exponential phase in 100 ml of GC medium, harvested by centrifugation, and resuspended in 5 ml buffer (20% Sucrose, 50 mM Tris-HCl, 50 mM EDTA, pH 8.0). After 10 minutes incubation on ice, the bacteria were lysed by adding 10 ml lysis solution (50 mM NaCl, 1% Na-SARKOSYLTM, 50 μg/ml Proteinase K), and the suspension was incubated at 37° C. for 2 hours. Two phenol extractions (equilibrated to pH 8) and one CHCl3/isoamylalcohol (24:1) extraction were performed. DNA was precipitated by addition of 0.3M sodium acetate and 2 volumes ethanol, and was collected by centrifugation. The pellet was washed once with 70% ethanol and redissolved in 4.0 ml TE buffer (10 mM Tris-HCl, 1 mM EDTA, pH 8). The DNA concentration was measured by reading the OD at 260 nm.
Oligonucleotide Design
Synthetic oligonucleotide primers were designed on the basis of the coding sequence of each ORF, using (a) the meningococcus B sequence when available, or (b) the gonococcus/meningococcus A sequence, adapted to the codon preference usage of meningococcus. Any predicted signal peptides were omitted, by deducing the 5′-end amplification primer sequence immediately downstream from the predicted leader sequence.
For most ORFs, the 5′ primers included two restriction enzyme recognition sites (BamHI-NdeI, BamHI-NheI, EcoRI-NdeI or EcoRI-NheI), depending on the restriction pattern of the gene of interest. The 3′ primers included a XhoI or a HindIII restriction site (table 1). This procedure was established in order to direct the cloning of each amplification product (corresponding to each ORF) into two different expression systems: pGEX-KG (using either BamHI-XhoI, BamHI-HindIII, EcoRI-XhoI, or EcoRI-HindIII), and pET21b+(using either NdeI-XhoI, NheI-XhoI, NdeI-HindIII, or NheI-HindIII).









5′-end primer tail:




CGCGGATCCCATATG
(BamHI-NdeI)
(SEQ ID 3288)


CGCGGATCCGCTAGC
(BamHI-NheI)
(SEQ ID 3289)


CCGGAATTCTAGATATC
(EcoRI-NdeI)
(SEQ ID 3290)


CCGGAATTCTAGCTAGC
(EcoRI-NheI)
(SEQ ID 3291)


 


3′-end primer tail:




CCCGCTCGAG
(XhoI)
(SEQ ID 3292)


CCCGCTCGAG
(HindIII)
(SEQ ID 3293)






For cloning ORFs into the pGEX-His Vector, the 5′ and 3′ primers contained only one restriction enzyme site (EcoRI, KpnI or SaII for the 5′ primers and PstI, XbaI, SphI or SaII for the 3′ primers). Again restriction sites were chosen according to the particular restriction pattern of the gene (table 1).









5′-end primer tail:




(AAA)AAAGAATTC
(EcoRI)
(SEQ ID 3294)


(AAA)AAAGGATCC
(KpnI)
(SEQ ID 3295)


 


3′-end primer tail:




(AAA)AAACTGCAG
(PstI)
(SEQ ID 3296)


(AAA)AAATCTAGA
(XbaI)
(SEQ ID 3297)


AAAGCATGC
(SphI)
(SEQ ID 3298)


 


5′ or 3′-end primer tail:




AAAAAAGAATCC
(PstI)
(SEQ ID 3299)






As well as containing the restriction enzyme recognition sequences, the primers included nucleotides which hybridized to the sequence to be amplified. The melting temperature depended on the number and type of hybridizing nucleotides in the whole primer, and was determined for each primer using the formulae:

Tm=4(G+C)+2(A+T)  (tail excluded)

Tm=64.9+0.41(% GC)−600/N  (whole primer)

The melting temperature of the selected oligonucleotides were usually 65-70° C. for the whole oligo and 50-55° C. for the hybridising region alone.
Table 1 shows the forward and reverse primers used for each amplification. In certain cases, the sequences of the primer does not match exactly the sequence of the predicted ORF. This is because when initial amplifications were performed, the complete 5′ and/or 3′ sequences for some meningococcal B ORFs were not be known. However, the corresponding sequences had been identified in Gonococcus or in Meningococcus A. Hence, when the Meningococcus B sequence was incomplete or uncertain, Gonococcus or in Meningococcus A sequences were used as the basis for the primer design. These sequences were altered to take account of codon preference. It can be appreciated that, once the complete sequence is identified, this approach will no longer be necessary.
Oligonucleotides were synthesized using a Perkin Elmer 394 DNA/RNA SYNTHESIZERTM, eluted from the columns in 2.0 ml NH4OH, and deprotected by 5 hours incubation at 56° C. The oligos were precipitated by addition of 0.3M Na-Acetate and 2 volumes ethanol. The samples were centrifuged and the pellets resuspended in either 100 μl or 1.0 ml of water. The OD260 was determined using a Perkin Elmer LAMBDA BIOTM spectophotometer and the concentration adjusted to 2-10 pmol/μl.
Amplification
The standard PCR protocol was as follows: 50-200 ng of genomic DNA was used as a template in the presence of 20-40 μM of each oligonucleotide primer, 400-800 μM dNTPs solution, 1×PCR buffer (including 1.5 mM MgCl2), 2.5 units TaqI DNA polymerase (using Perkin-Elmer AMPLITAQTM, GIBCO Platinum, Pwo DNA polymerase, or Tahara Shuzo Taq polymerase). In some cases, PCR was optimised by the addition of 10 μl of DMSO or 50 μl of 2M Betaine.
After a hot start (adding the polymerase during a preliminary 3 minute incubation of the whole mix at 95° C.), each sample underwent a two-step amplification. The first 5 cycles were performed using the hybridization temperature that excluded the restriction enzyme tail of the primer (see above). This was followed by 30 cycles using the hybridization temperature calculated for the whole length oligos. The cycles were followed by a final 10 minute extension step at 72° C. The standard cycles were as follows:















Denaturation
Hybridisation
Elongation






















First 5 cycles
30
seconds
30
seconds
30-60
seconds



95°
C.
50-55°
C.
72°
C.


Last 30 cycles
30
seconds
30
seconds
30-60
seconds



95°
C.
65-70°
C.
72°
C.









The elongation time varied according to the length of the ORF to be amplified. Amplifications were performed using either a 9600 or a 2400 Perkin Elmer GeneAmp PCR System. To check the results, 1/10 of the amplification volume was loaded onto a 1-1.5% (w/v) agarose gel and the size of each amplified fragment compared with a DNA molecular weight marker.
The amplified DNA was either loaded directly on a 1% agarose gel or first precipitated with ethanol and resuspended in a volume suitable to be loaded on a 1.0% agarose gel. The DNA fragment corresponding to the band of the correct size was purified using the Qiagen Gel Extraction Kit, following the manufacturer's protocol. DNA fragments were eluted in a volume of 30 μl or 50 μl of either H2O or 10 mM Tris, pH 8.5.
Digestion of PCR Fragments
The purified DNA corresponding to the amplified fragment was double-digested with the appropriate restriction enzymes for; cloning into pET-21b+ and expressing the protein as a C-terminus His-tagged fusion, for cloning into pGEX-KG and expressing the protein as a N-terminus GST-fusion, and for cloning into pGEX-His and expressing the protein as a N-terminus GST-his tagged fusion.
Each purified DNA fragment was incubated at 37° C. for 3 hours to overnight with 20 units of appropriate restriction enzyme (New England Biolabs) in a either 30 or 40 μl in the presence of suitable digestion buffer. Digested products were purified using the QIAquick PCR purification kit (following the manufacturer's instructions) and eluted in a final volume of 30 or 50 μl of either H2O or 10 mM Tris, pH 8.5. The DNA concentration was determined by quantitative agarose gel electrophoresis (1.0% gel) in the presence of a titrated molecular weight marker.
Digestion of the Cloning Vectors (pET22B, pGEX-KG, pTRC-His a, pET21b+, pGEX-KG, and pGEX-His)
The vector pGEX-His is a modified pGEX-2T vector carrying a region encoding six histidine residues upstream of the thrombin cleavage site and containing the multiple cloning site of the vector pTRC99 (Pharmacia). 10 μg plasmid was double-digested with 50 units of each restriction enzyme in 200 μl reaction volume in the presence of appropriate buffer by overnight incubation at 37° C. After loading the whole digestion on a 1% agarose gel, the band corresponding to the digested vector was purified from the gel using the Qiagen QIAquick Gel Extraction Kit and the DNA was eluted in 50 μl of 10 mM Tris-HCl, pH 8.5. The DNA concentration was evaluated by measuring OD260 of the sample, and adjusted to 50 μg/μl. 1 μl of plasmid was used for each cloning procedure.
10 μg plasmid was double-digested with 50 units of each restriction enzyme in 200 reaction volume in the presence of appropriate buffer by overnight incubation at 37° C. The digest was loaded onto a 1% agarose gel and the band corresponding to the digested vector purified using the Qiagen QIAquick Gel Extraction Kit. DNA was eluted in 50 μl of 10 mM Tris-HCl, pH 8.5. The DNA concentration was evaluated by measuring OD260 and the concentration adjusted to 50 μg/μl. 1 μl of plasmid was used for each cloning procedure.
Cloning
For some ORFs, the fragments corresponding to each ORF, previously digested and purified, were ligated in both pET22b and pGEX-KG. In a final volume of 20 μl, a molar ratio of 3:1 fragment/vector was ligated using 0.5 μl of NEB T4 DNA ligase (400 units/μl), in the presence of the buffer supplied by the manufacturer. The reaction was incubated at room temperature for 3 hours. In some experiments, ligation was performed using the Boheringer “Rapid Ligation Kit”, following the manufacturer's instructions.
In order to introduce the recombinant plasmid in a suitable strain, 100 μl E. coli DH5 competent cells were incubated with the ligase reaction solution for 40 minutes on ice, then at 37° C. for 3 minutes, then, after adding 800 μl LB broth, again at 37° C. for 20 minutes. The cells were then centrifuged at maximum speed in an Eppendorf microfuge and resuspended in approximately 200 μl of the supernatant. The suspension was then plated on LB ampicillin (100 mg/ml).
The screening of the recombinant clones was performed by growing 5 randomly-chosen colonies overnight at 37° C. in either 2 ml (pGEX or pTC clones) or 5 ml (pET clones) LB broth+100 μg/ml ampicillin. The cells were then pelletted and the DNA extracted using the Qiagen QIAprep Spin Miniprep Kit, following the manufacturer's instructions, to a final volume of 30 μl. 5 μl of each individual miniprep (approximately 1 g) were digested with either NdeI/XhoI or BamHI/XhoI and the whole digestion loaded onto a 1-1.5% agarose gel (depending on the expected insert size), in parallel with the molecular weight marker (1 Kb DNA Ladder, GIBCO). The screening of the positive clones was made on the base of the correct insert size.
For other ORFs, the fragments corresponding to each ORF, previously digested and purified, were ligated in both pET21b+ and pGEX-KG. A molar ratio of 3:1 fragment/vector was used in a final volume of 20 μl, that included 0.5 μl of T4 DNA ligase (400 units/μl, NEB) and ligation buffer supplied by the manufacturer. The reaction was performed at room temperature for 3 hours. In some experiments, ligation was performed using the Boheringer “Rapid Ligation Kit” and the manufacturer's protocol.
Recombinant plasmid was transformed into 100 μl of competent E. coli DH5 or HB101 by incubating the ligase reaction solution and bacteria for 40 minutes on ice then at 37° C. for 3 minutes. This was followed by addition of 800 μl LB broth and incubation at 37° C. for 20 minutes. The cells were then centrifuged at maximum speed in an Eppendorf microfuge, resuspended in approximately 200 μl of the supernatant, and plated on LB ampicillin (100 mg/ml) agar.
Screening for recombinant clones was performed by growing 5 randomly selected colonies overnight at 37° C. in either 2.0 ml (pGEX-KG clones) or 5.0 ml (pET clones) LB broth+100 μg/ml ampicillin. Cells were pelleted and plasmid DNA extracted using the Qiagen QIAprep Spin Miniprep Kit, following the manufacturer's instructions. Approximately 1 μg of each individual miniprep was digested with the appropriate restriction enzymes and the digest loaded onto a 1-1.5% agarose gel (depending on the expected insert size), in parallel with the molecular weight marker (1 kb DNA Ladder, GIBCO). Positive clones were selected on the basis of the size of the insert.
ORFs were cloned in PGEX-His, by doubly-digesting the PC product and ligating into similarly digested vector. After cloning, recombinant plasmids were transformed into the E. coli host W3110. Individual clones were grown overnight at 37° C. in LB broth with 50 μg/ml ampicillin.
Certain ORFs may be cloned into the pGEX-HIS vector using EcoRI-PstI cloning sites, or EcoRI-SalI, or SalI-PstI. After cloning, the recombinant plasmids may be introduced in the E. coli host W3110.
Expression
Each ORF cloned into the expression vector may then be transformed into the strain suitable for expression of the recombinant protein product. 1 μl of each construct was used to transform 30 μl of E. coli BL21 (pGEX vector), E. coli TOP 10 (pTRC vector) or E. coli BL21-DE3 (pET vector), as described above. In the case of the pGEX-His vector, the same E. coli strain (W3110) was used for initial cloning and expression. Single recombinant colonies were inoculated into 2 ml LB+Amp (100 μg/ml), incubated at 37° C. overnight, then diluted 1:30 in 20 ml of LB+Amp (100 μs/ml) in 100 ml flasks, making sure that the OD600 ranged between 0.1 and 0.15. The flasks were incubated at 30° C. into gyratory water bath shakers until OD indicated exponential growth suitable for induction of expression (0.4-0.8 OD for pET and pTRC vectors; 0.8-10D for pGEX and pGEX-His vectors). For the pET, pTRC and pGEX-His vectors, the protein expression was induced by addiction of 1 mM IPTG, whereas in the case of pGEX system the final concentration of IPTG was 0.2 mM. After 3 hours incubation at 30° C., the final concentration of the sample was checked by OD. In order to check expression, 1 ml of each sample was removed, centrifuged in a microfuge, the pellet resuspended in PBS, and analysed by 12% SDS-PAGE with Coomassie Blue staining. The whole sample was centrifuged at 6000 g and the pellet resuspended in PBS for further use.
GST-Fusion Proteins Large-Scale Purification.
For some ORFs, a single colony was grown overnight at 37° C. on LB+Amp agar plate. The bacteria were inoculated into 20 ml of LB+Amp liquid culture in a water bath shaker and grown overnight. Bacteria were diluted 1:30 into 600 ml of fresh medium and allowed to grow at the optimal temperature (20-37° C.) to OD550 0.8-1. Protein expression was induced with 0.2 mM IPTG followed by three hours incubation. The culture was centrifuged at 8000 rpm at 4° C. The supernatant was discarded and the bacterial pellet was resuspended in 7.5 ml cold PBS. The cells were disrupted by sonication on ice for 30 sec at 40 W using a Branson sonifier B-15, frozen and thawed two times and centrifuged again. The supernatant was collected and mixed with 150 μl GLUTATHIONE-SEPHAROSE 4BTM resin (Pharmacia) (previously washed with PBS) and incubated at room temperature for 30 minutes. The sample was centrifuged at 700 g for 5 minutes at 4 C. The resin was washed twice with 10 ml cold PBS for 10 minutes, resuspended in 1 ml cold PBS, and loaded on a disposable column. The resin was washed twice with 2 ml cold PBS until the flow-through reached OD280 of 0.02-0.06. The GST-fusion protein was eluted by addition of 700 μl cold Glutathione elution buffer (10 mM reduced glutathione, 50 mM Tris-HCl) and fractions collected until the OD280 was 0.1. 21 μl of each fraction were loaded on a 12% SDS gel using either Biorad SDS-PAGE Molecular weight standard broad range (M1) (200, 116.25, 97.4, 66.2, 45, 31, 21.5, 14.4, 6.5 kDa) or Amersham Rainbow Marker (M′′) (220, 66, 46, 30, 21.5, 14.3 kDa) as standards. As the MW of GST is 26 kDa, this value must be added to the MW of each GST-fusion protein.
For other ORFs, for each clone to be purified as a GST-fusion, a single colony was streaked out and grown overnight at 37° C. on LB/Amp (100 μg/ml) agar plate. An isolated colony from this plate was inoculated into 20 ml of LB/Amp (100 μg/ml) liquid medium and grown overnight at 37° C. with shaking. The overnight culture was diluted 1:30 into 600 ml of LB/Amp (100 μg/ml) liquid medium and allowed to grow at the optimal temperature (20-37° C.) until the OD550 reached 0.6-0.8. Recombinant protein expression was induced by addition of IPTG (final concentration 0.2 mM) and the culture incubated for a further 3 hours. The bacteria were harvested by centrifugation at 8000×g for 15 min at 4° C.
The bacterial pellet was resuspended in 7.5 ml cold PBS. Cells were disrupted by sonication on ice for 30 sec at 40 W using a Branson sonifier 450 and centrifuged at 13 000×g for 30 min at 4° C. The supernatant was collected and mixed with 15 μl GLUTATHIONE-SEPHAROSE 4BTM resin (Pharmacia), previously equilibrated with PBS, and incubated at room temperature with gentle agitation for 30 min. The batch-wise preparation was centrifuged at 700×g for 5 min at 4° C. and the supernatant discarded. The resin was washed twice (batchwise) with 10 ml cold PBS for 10 min, resuspended in 1 ml cold PBS, and loaded onto a disposable column. The resin continued to be washed twice with cold PBS, until the OD280nm of the flow-through reached 0.02-0.01. The GST-fusion protein was eluted by addition of 700 μl cold glutathione elution buffer (10 mM reduced glutathione, 50 mM Tris-HCl pH 8.0) and fractions collected, until the OD280nm of the eluate indicated all the recombinant protein was obtained. 20 μl aliquots of each elution fraction were analyzed by SDS-PAGE using a 12% gel. The molecular mass of the purified proteins was determined using either the Bio-Rad broad range molecular weight standard (M1) (200, 116, 97.4, 66.2, 45.0, 31.0, 21.5, 14.4, 6.5 kDa) or the Amersham Rainbow Marker (M2) (220, 66.2, 46.0, 30.0, 21.5, 14.3 kDa). The molecular weights of GST-fusion proteins are a combination of the 26 kDa GST protein and its fusion partner. Protein concentrations were estimated using the Bradford assay.
His-Fusion Soluble Proteins Large-Scale Purification.
For some ORFs, a single colony was grown overnight at 37° C. on a LB+Amp agar plate. The bacteria were inoculated into 20 ml of LB+Amp liquid culture and incubated overnight in a water bath shaker. Bacteria were diluted 1:30 into 600 ml fresh medium and allowed to grow at the optimal temperature (20-37° C.) to OD550 0.6-0.8. Protein expression was induced by addition of 1 mM IPTG and the culture further incubated for three hours. The culture was centrifuged at 8000 rpm at 4° C., the supernatant was discarded and the bacterial pellet was resuspended in 7.5 ml cold 10 mM imidazole buffer (300 mM NaCl, 50 mM phosphate buffer, 10 mM imidazole, pH 8). The cells were disrupted by sonication on ice for 30 sec at 40 W using a Branson sonifier B-15, frozen and thawed two times and centrifuged again. The supernatant was collected and mixed with 150 μl Ni2+-resin (Pharmacia) (previously washed with 10 mM imidazole buffer) and incubated at room temperature with gentle agitation for 30 minutes. The sample was centrifuged at 700 g for 5 minutes at 4° C. The resin was washed twice with 10 ml cold 10 mM imidazole buffer for 10 minutes, resuspended in 1 ml cold 10 mM imidazole buffer and loaded on a disposable column. The resin was washed at 4° C. with 2 ml cold 10 mM imidazole buffer until the flow-through reached the OD280 of 0.02-0.06. The resin was washed with 2 ml cold 20 mM imidazole buffer (300 mM NaCl, 50 mM phosphate buffer, 20 mM imidazole, pH 8) until the flow-through reached the O.D280 of 0.02-0.06. The His-fusion protein was eluted by addition of 700 μl cold 250 mM imidazole buffer (300 mM NaCl, 50 mM phosphate buffer, 250 mM imidazole, pH 8) and fractions collected until the O.D280 was 0.1. 21 μl of each fraction were loaded on a 12% SDS gel.
His-Fusion Insoluble Proteins Large-Scale Purification.
A single colony was grown overnight at 37° C. on a LB+Amp agar plate. The bacteria were inoculated into 20 ml of LB+Amp liquid culture in a water bath shaker and grown overnight. Bacteria were diluted 1:30 into 600 ml fresh medium and let to grow at the optimal temperature (37° C.) to O.D550 0.6-0.8. Protein expression was induced by addition of 1 mM IPTG and the culture further incubated for three hours. The culture was centrifuged at 8000 rpm at 4° C. The supernatant was discarded and the bacterial pellet was resuspended in 7.5 ml buffer B (urea 8M, 10 mM Tris-HCl, 100 mM phosphate buffer, pH 8.8). The cells were disrupted by sonication on ice for 30 sec at 40 W using a Branson sonifier B-15, frozen and thawed twice and centrifuged again. The supernatant was stored at −20° C., while the pellets were resuspended in 2 ml guanidine buffer (6M guanidine hydrochloride, 100 mM phosphate buffer, 10 mM Tris-HCl, pH 7.5) and treated in a homogenizer for 10 cycles. The product was centrifuged at 13000 rpm for 40 minutes. The supernatant was mixed with 15 μl Ni2+-resin (Pharmacia) (previously washed with buffer B) and incubated at room temperature with gentle agitation for 30 minutes. The sample was centrifuged at 700 g for 5 minutes at 4° C. The resin was washed twice with 10 ml buffer B for 10 minutes, resuspended in 1 ml buffer B, and loaded on a disposable column. The resin was washed at room temperature with 2 ml buffer B until the flow-through reached the OD280 of 0.02-0.06. The resin was washed with 2 ml buffer C (urea 8M, 10 mM Tris-HCl, 100 mM phosphate buffer, pH 6.3) until the flow-through reached the O.D280 of 0.02-0.06. The His-fusion protein was eluted by addition of 700 μl elution buffer (urea 8M, 10 mM Tris-HCl, 100 mM phosphate buffer, pH 4.5) and fractions collected until the OD280 was 0.1. 21 μl of each fraction were loaded on a 12% SDS gel.
Purification of His-Fusion Proteins.
For each clone to be purified as a His-fusion, a single colony was streaked out and grown overnight at 37° C. on LB/Amp (100 μg/ml) agar plate. An isolated colony from this plate was inoculated into 20 ml of LB/Amp (100 μg/ml) liquid medium and grown overnight at 37° C. with shaking. The overnight culture was diluted 1:30 into 600 ml of LB/Amp (100 μg/ml) liquid medium and allowed to grow at the optimal temperature (20-37° C.) until the OD550 reached 0.6-0.8. Expression of recombinant protein was induced by addition of IPTG (final concentration 1.0 mM) and the culture incubated for a further 3 hours. The bacteria were harvested by centrifugation at 8000×g for 15 min at 4° C.
The bacterial pellet was resuspended in 7.5 ml either (i) cold buffer A (300 mM NaCl, 50 mM phosphate buffer, 10 mM imidazole, pH 8.0) for soluble proteins or (ii) buffer B (8M urea, 10 mM TrisHCl, 100 mM phosphate buffer, pH 8.8) for insoluble proteins. Cells were disrupted by sonication on ice four times for 30 sec at 40 W using a Branson sonifier 450 and centrifuged at 13 000×g for 30 min at 4° C. For insoluble proteins, pellets were resuspended in 2.0 ml buffer C (6M guanidine hydrochloride, 100 mM phosphate buffer, 10 mM Tris-HCl, pH 7.5) and treated with a Dounce homogenizer for 10 cycles. The homogenate was centrifuged at 13 000×g for 40 min and the supernatant retained.
Supernatants for both soluble and insoluble preparations were mixed with 15 μl Ni2+-resin (previously equilibrated with either buffer A or buffer B, as appropriate) and incubated at room temperature with gentle agitation for 30 min. The resin was CHELATING SEPHAROSE FAST FLOWTM (Pharmacia), prepared according to the manufacturers protocol. The batch-wise preparation was centrifuged at 700×g for 5 min at 4° C. and the supernatant discarded. The resin was washed twice (batch-wise) with 10 ml buffer A or B for 10 min, resuspended in 1.0 ml buffer A or B and loaded onto a disposable column. The resin continued to be washed with either (i) buffer A at 4° C. or (ii) buffer B at room temperature, the OD280nm of the flow-through reached 0.02-0.01. The resin was further washed with either (i) cold buffer C (300 mM NaCl, 50 mM phosphate buffer, 20 mM imidazole, pH 8.0) or (ii) buffer D (8M urea, 10 mM Tris-HCl, 100 mM phosphate buffer, pH 6.3) until the OD280nm of the flow-through reached 0.02-0.01. The His-fusion protein was eluted by addition of 700 μl of either (1) cold elution buffer A (300 mM NaCl, 50 mM phosphate buffer, 250 mM imidazole, pH 8.0) or (ii) elution buffer B (8 M urea, 10 mM Tris-HCl, 100 mM phosphate buffer, pH 4.5) and fractions collected until the O.D280nm indicated all the recombinant protein was obtained. 20 μl aliquots of each elution fraction were analyzed by SDS-PAGE using a 12% gel. Protein concentrations were estimated using the Bradford assay.
His-Fusion Proteins Renaturation
In the cases where denaturation was required to solubilize proteins, a renaturation step was employed prior to immunization. Glycerol was added to the denatured fractions obtained above to a final concentration of 10% (v/v). The proteins were then diluted to 200 μg/ml using dialysis buffer I (10% (v/v) glycerol, 0.5M arginine, 50 mM phosphate buffer, 5 mM reduced glutathione, 0.5 mM oxidised glutathione, 2M urea, pH 8.8) and dialysed against the same buffer for 12-14 hours at 4° C. Further dialysis was performed with buffer II (10% (v/v) glycerol, 0.5M arginine, 50 mM phosphate buffer, 50 mM reduced glutathione, 5.0 mM oxidised glutathione, pH 8.8) for 12-14 hours at 4° C.
Alternatively, 10% glycerol was added to the denatured proteins. The proteins were then diluted to 20 μg/ml using dialysis buffer I (10% glycerol, 0.5M arginine, 50 mM phosphate buffer, 5 mM reduced glutathione, 0.5 mM oxidised glutathione, 2M urea, pH 8.8) and dialysed against the same buffer at 4° C. for 12-14 hours. The protein was further dialysed against dialysis buffer II (10% glycerol, 0.5M arginine, 50 mM phosphate buffer, 5 mM reduced glutathione, 0.5 mM oxidised glutathione, pH 8.8) for 12-14 hours at 4° C.
Protein concentration was evaluated using the formula:

Protein (mg/ml)=(1.55×OD280)−(0.76×OD260)

Purification of Proteins

To analyse the solubility, pellets obtained from 3.0 ml cultures were resuspended in 500 μl buffer M1 (PBS pH 7.2). 25 μl of lysozyme (10 mg/ml) was added and the bacteria incubated for 15 min at 4° C. Cells were disrupted by sonication on ice four times for 30 sec at 40 W using a Branson sonifier 450 and centrifuged at 13 000×g for 30 min at 4° C. The supernatant was collected and the pellet resuspended in buffer M2 [8M urea, 0.5M NaCl, 20 mM imidazole and 0.1 M NaH2PO4] and incubated for 3 to 4 hours at 4° C. After centrifugation, the supernatant was collected and the pellet resuspended in buffer M3 [6M guanidinium-HCl, 0.5M NaCl, 20 mM imidazole and 0.1 M NaH2PO4] overnight at 4° C. The supernatants from all steps were analysed by SDS-PAGE. Some proteins were found to be soluble in PBS, others needed urea or guanidinium-HCl for solubilization.
For preparative scale purification, 500 ml cultures were induced and fusion proteins solubilized in either buffer M1, M2, or M3 using the procedure described above. Crude extracts were loaded onto a Ni-NTA superflow column (Qiagen) equilibrated with buffer M1, M2, or M3 depending on the solubilization buffer employed. Unbound material was eluted with the corresponding buffer containing 500 mM imidazole then dialysed against the same buffer in the absence of imidazole.
Mice Immunisations
20 μg of each purified protein are used to immunise mice intraperitoneally. In the case of some ORFs, Balb-C mice were immunised with Al(OH)3 as adjuvant on days 1, 21 and 42, and immune response was monitored in samples taken on day 56. For other ORFs, CD1 mice could be immunised using the same protocol. For ORFs 25 and 40, CD1 mice were immunised using Freund's adjuvant, and the same immunisation protocol was used, except that the immune response was measured on day 42, rather than 56. Similarly, for still other ORFs, CD1 mice were immunised with Freund's adjuvant, but the immune response was measured on day 49. Alternatively, 20 μg of each purified protein was mixed with Freund's adjuvant and used to immunize CD1 mice intraperitoneally. For many of the proteins, the immunization was performed on days 1, 21 and 35, and immune response was monitored in samples taken on days 34 and 49. For some proteins, the third immunization was performed on day 28, rather than 35, and immune response was measured on days 20 and 42, rather than 34 and 49.
ELISA Assay (Sera Analysis)
The acapsulated MenB M7 strain was plated on chocolate agar plates and incubated overnight at 37° C. Bacterial colonies were collected from the agar plates using a sterile dracon swab and inoculated into 7 ml of Mueller-Hinton Broth (Difco) containing 0.25% Glucose. Bacterial growth was monitored every 30 minutes by following OD620. The bacteria were let to grow until the OD reached the value of 0.3-0.4. The culture was centrifuged for 10 minutes at 10000 rpm. The supernatant was discarded and bacteria were washed once with PBS, resuspended in PBS containing 0.025% formaldehyde, and incubated for 2 hours at room temperature and then overnight at 4° C. with stirring. 100 μl bacterial cells were added to each well of a 96 well Greiner plate and incubated overnight at 4° C. The wells were then washed three times with PBT washing buffer (0.1% TWEEN-20TM in PBS). 200 μl of saturation buffer (2.7% Polyvinylpyrrolidone 10 in water) was added to each well and the plates incubated for 2 hours at 37° C. Wells were washed three times with PBT. 200 μl of diluted sera (Dilution buffer: 1% BSA, 0.1% TWEEN-20TM, 0.1% NaN3 in PBS) were added to each well and the plates incubated for 90 minutes at 37° C. Wells were washed three times with PBT. 100 μl of HRP-conjugated rabbit anti-mouse (Dako) serum diluted 1:2000 in dilution buffer were added to each well and the plates were incubated for 90 minutes at 37° C. Wells were washed three times with PBT buffer. 100 μl of substrate buffer for HRP (25 ml of citrate buffer pH5, 10 mg of O-phenildiamine and 10 μl of H2O) were added to each well and the plates were left at room temperature for 20 minutes. 100 μl H2SO4 was added to each well and OD490 was followed. The ELISA was considered positive when OD490 was 2.5 times the respective pre-immune sera.
Alternatively, The acapsulated MenB M7 strain was plated on chocolate agar plates and incubated overnight at 37° C. Bacterial colonies were collected from the agar plates using a sterile dracon swab and inoculated into Mueller-Hinton Broth (Difco) containing 0.25% Glucose. Bacterial growth was monitored every 30 minutes by following OD620. The bacteria were let to grow until the OD reached the value of 0.3-0.4. The culture was centrifuged for 10 minutes at 10 000 rpm. The supernatant was discarded and bacteria were washed once with PBS, resuspended in PBS containing 0.025% formaldehyde, and incubated for 1 hour at 37° C. and then overnight at 4° C. with stirring. 100 μl bacterial cells were added to each well of a 96 well Greiner plate and incubated overnight at 4° C. The wells were then washed three times with PBT washing buffer (0.1% TWEEN-20TM in PBS). 200 μl of saturation buffer (2.7% Polyvinylpyrrolidone 10 in water) was added to each well and the plates incubated for 2 hours at 37° C. Wells were washed three times with PBT. 200 μl of diluted sera (Dilution buffer: 1% BSA, 0.1% TWEEN-20TM, 0.1% NaN3 in PBS) were added to each well and the plates incubated for 2 hours at 37° C. Wells were washed three times with PBT. 100 μl of HRP-conjugated rabbit anti-mouse (Dako) serum diluted 1:2000 in dilution buffer were added to each well and the plates were incubated for 90 minutes at 37° C. Wells were washed three times with PBT buffer. 100 μl of substrate buffer for HRP (25 ml of citrate buffer pH5, 10 mg of O-phenildiamine and 10 μl of H2O2) were added to each well and the plates were left at room temperature for 20 minutes. 100 μl H2SO4 was added to each well and OD490 was followed. The ELISA titers were calculated arbitrarily as the dilution of sera which gave an OD490 value of 0.4 above the level of preimmune sera. The ELISA was considered positive when the dilution of sera with OD490 of 0.4 was higher than 1:400.
FACScan Bacteria Binding Assay Procedure.
The acapsulated MenB M7 strain was plated on chocolate agar plates and incubated overnight at 37° C. Bacterial colonies were collected from the agar plates using a sterile dracon swab and inoculated into 4 tubes containing 8 ml each Mueller-Hinton Broth (Difco) containing 0.25% glucose. Bacterial growth was monitored every 30 minutes by following OD620. The bacteria were let to grow until the OD reached the value of 0.35-0.5. The culture was centrifuged for 10 minutes at 4000 rpm. The supernatant was discarded and the pellet was resuspended in blocking buffer (1% BSA, 0.4% NaN3) and centrifuged for 5 minutes at 4000 rpm. Cells were resuspended in blocking buffer to reach OD620 of 0.07. 100 μl bacterial cells were added to each well of a Costar 96 well plate. 100 μl of diluted (1:200) sera (in blocking buffer) were added to each well and plates incubated for 2 hours at 4° C. Cells were centrifuged for 5 minutes at 4000 rpm, the supernatant aspirated and cells washed by addition of 200 μl/well of blocking buffer in each well. 100 μl of R-Phicoerytrin conjugated F(ab)2 goat anti-mouse, diluted 1:100, was added to each well and plates incubated for 1 hour at 4° C. Cells were spun down by centrifugation at 4000 rpm for 5 minutes and washed by addition of 200 μl/well of blocking buffer. The supernatant was aspirated and cells resuspended in 200 μl/well of PBS, 0.25% formaldehyde. Samples were transferred to FACScan tubes and read. The condition for FACScan setting were: FL1 on, FL2 and FL3 off; FSC-H Treshold:92; FSC PMT Voltage: E 02; SSC PMT: 474; Amp. Gains 7.1; FL-2 PMT: 539. Compensation values: 0.
OMV Preparations
Bacteria were grown overnight on 5 GC plates, harvested with a loop and resuspended in 10 ml 20 mM Tris-HCl. Heat inactivation was performed at 56° C. for 30 minutes and the bacteria disrupted by sonication for 10′ on ice (50% duty cycle, 50% output). Unbroken cells were removed by centrifugation at 5000 g for 10 minutes and the total cell envelope fraction recovered by centrifugation at 50000 g at 4° C. for 75 minutes. To extract cytoplasmic membrane proteins from the crude outer membranes, the whole fraction was resuspended in 2% sarkosyl (Sigma) and incubated at room temperature for 20 minutes. The suspension was centrifuged at 10000 g for 10 minutes to remove aggregates, and the supernatant further ultracentrifuged at 50000 g for 75 minutes to pellet the outer membranes. The outer membranes were resuspended in 10 mM Tris-HCl, pH8 and the protein concentration measured by the Bio-Rad Protein assay, using BSA as a standard.
Whole Extracts Preparation
Bacteria were grown overnight on a GC plate, harvested with a loop and resuspended in 1 ml of 20 mM Tris-HCl. Heat inactivation was performed at 56° C. for 30′ minutes.
Western Blotting
Purified proteins (500 ng/lane), outer membrane vesicles (51 μg) and total cell extracts (25 μg) derived from MenB strain 2996 were loaded onto a 12% SDS-polyacrylamide gel and transferred to a nitrocellulose membrane. The transfer was performed for 2 hours at 150 mA at 4° C., using transfer buffer (0.3% Tris base, 1.44% glycine, 20% (v/v) methanol). The membrane was saturated by overnight incubation at 4° C. in saturation buffer (10% skimmed milk, 0.1% TRITON X100TM in PBS). The membrane was washed twice with washing buffer (3% skimmed milk, 0.1% TRITON X100TM in PBS) and incubated for 2 hours at 37° C. with mice sera diluted 1:200 in washing buffer. The membrane was washed twice and incubated for 90 minutes with a 1:2000 dilution of horseradish peroxidase labeled anti-mouse Ig. The membrane was washed twice with 0.1% TRITON X100TM in PBS and developed with the OPTI-4CN SUBSTRATE KITTM (Bio-Rad). The reaction was stopped by adding water.
Bactericidal Assay
MC58 and 2996 strains were grown overnight at 37° C. on chocolate agar plates. 5-7 colonies were collected and used to inoculate 7 ml Mueller-Hinton broth. The suspension was incubated at 37° C. on a nutator and let to grow until OD620 was in between 0.5-0.8. The culture was aliquoted into sterile 1.5 ml Eppendorf tubes and centrifuged for 20 minutes at maximum speed in a microfuge. The pellet was washed once in Gey's buffer (Gibco) and resuspended in the same buffer to an OD620 of 0.5, diluted 1:20000 in Gey's buffer and stored at 25° C.
50 μl of Gey's buffer/1% BSA was added to each well of a 96-well tissue culture plate. 25 μl of diluted (1:100) mice sera (dilution buffer: Gey's buffer/0.2% BSA) were added to each well and the plate incubated at 4° C. 25 μl of the previously described bacterial suspension were added to each well. 25 μl of either heat-inactivated (56° C. waterbath for 30 minutes) or normal baby rabbit complement were added to each well. Immediately after the addition of the baby rabbit complement, 22 μl of each sample/well were plated on Mueller-Hinton agar plates (time 0). The 96-well plate was incubated for 1 hour at 37° C. with rotation and then 22 μl of each sample/well were plated on Mueller-Hinton agar plates (time 1). After overnight incubation the colonies corresponding to time 0 and time 1 h were counted.
Gene Variability
The ORF4 and 919 genes were amplified by PCR on chromosomal DNA extracted from various Neisseria strains (see list of strains). The following oligonucleotides used as PCR primers were designed in the upstream and downstream regions of the genes:









orf 4.1 (forward)







(SEQ ID NO: 3266)









CGAATCCGGACGGCAGGACTC


 



orf 4.3 (reverse)







(SEQ ID NO: 3267)









GGCAGGGAATGGCGGATTAAAG


 



919.1 (forward)







(SEQ ID NO: 3268)









AAAATGCCTCTCCACGGCTG



or







(SEQ ID NO: 3269)









CTGCGCCCTGTGTTAAAATCCCCT


 



919.6 (reverse)







(SEQ ID NO: 3270)









CAAATAAGAAAGGAATTTTG



or







(SEQ ID NO: 3271)









GGTATCGCAAAACTTCGCCTTAATGCG






The PCR cycling conditions were:














 1 cycle
 2 min. at 94°


30 cycles
30 sec. at 94°



30 sec. at ~ 54° or ~ 60° (in according to Tm of the primers)



40 sec. at 72°


 1 cycle
 7 min. at 72°









The PCR products were purified from 1% agarose gel and sequenced using the following primers:










orf 4.1 (forward)







(SEQ ID NO: 3272)









CGAATCCGGACGGCAGGACTC



 



orf 4.2 (forward)







(SEQ ID NO: 3273)









CGACCGCGCCTTTGGGACTG



 



orf 4.3 (reverse)







(SEQ ID NO: 3274)









GGCAGGGAATGGCGGATTAAAG



 



orf 4.4 (reverse)







(SEQ ID NO: 3275)









TCTTTGAGTTTGATCCAACC



 



919.1 (forward)







(SEQ ID NO: 3276)









AAAATGCCTCTCCACGGCTG



or



 







(SEQ ID NO: 3277)









CTGCGCCCTGTGTTAAAATCCCCT



 



919.2 (forward)







(SEQ ID NO: 3278)









ATCCTTCCGCCTCGGCTGCG



 



919.3 (forward)







(SEQ ID NO: 3279)









AAAACAGCGGCACAATCGAC



 



919.4 (forward)







(SEQ ID NO: 3280)









ATAAGGGCTACCTCAAACTC



 



919.5 (forward)







(SEQ ID NO: 3281)









GCGCGTGGATTATTTTTGGG



 



919.6 (reverse)







(SEQ ID NO: 3282)









CAAATAAGAAAGGAATTTTG



or



 







(SEQ ID NO: 3283)









GGTATCGCAAAACTTCGCCTTAATGCG



 



919.7 (reverse)







(SEQ ID NO: 3284)









CCCAAGGTAATGTAGTGCCG



 



919.8 (reverse)







(SEQ ID NO: 3285)









TAAAAAAAAGTTCGACAGGG



 



919.9 (reverse)







(SEQ ID NO: 3286)









CCGTCCGCCTGTCGTCGCCC



 



919.10 (reverse)







(SEQ ID NO: 3287)









TCGTTCCGGCGGGGTCGGGG






All documents cited herein are incorporated by reference in their entireties.
The following Examples are presented to illustrate, not limit, the invention.
Example 1
Using the above-described procedures, the following oligonucleotide primers were employed in the polymerase chain reaction (PCR) assay in order to clone the ORFs as indicated:







TABLE 1







Oligonucleotides used for PCR for Examples 2-10










ORF
Primer
Sequence
Restriction sites





279
Forward
CGCGGATCCCATATG-TTGCCTGCAATCACGATT
BamHI-NdeI




<SEQ ID 3021>



Reverse
CCCGCTCGAG-TTTAGAAGCGGGCGGCAA <SEQ
XhoI




ID 3022>


 


519
Forward
CGCGGATCCCATATG-TTCAAATCCTTTGTCGTCA
BamHI-NdeI




<SEQ ID 3023>



Reverse
CCCGCTCGAG-TTTGGCGGTTTTGCTGC <SEQ ID
XhoI




3024>


 


576
Forward
CGCGGATCCCATATG-GCCGCCCCCGCATCT
BamHI-NdeI




<SEQ ID 3025>



Reverse
CCCGCTCGAG-ATTTACTTTTTTGATGTCGAC
XhoI




<SEQ ID 3026>


 


919
Forward
CGCGGATCCCATATG-TGCCAAAGCAAGAGCATC
BamHI-NdeI




<SEQ ID 3027>



Reverse
CCCGCTCGAG-CGGGCGGTATTCGGG <SEQ ID
XhoI




3028>


 


121
Forward
CGCGGATCCCATATG-GAAACACAGCTTTACAT
BamHI-NdeI




<SEQ ID 3029>



Reverse
CCCGCTCGAG-ATAATAATATCCCGCGCCC <SEQ
XhoI




ID 3030>


 


128
Forward
CGCGGATCCCATATG-ACTGACAACGCACT <SEQ
BamHI-NdeI




ID 3031>



Reverse
CCCGCTCGAG-GACCGCGTTGTCGAAA <SEQ ID
XhoI




3032>


 


206
Forward
CGCGGATCCCATATG-AAACACCGCCAACCGA
BamHI-NdeI




<SEQ ID 3033>



Reverse
CCCGCTCGAG-TTCTGTAAAAAAAGTATGTGC
XhoI




<SEQ ID 3034>


 


287
Forward
CCGGAATTCTAGCTAGC-CTTTCAGCCTGCGGG
EcoRI-NheI




<SEQ ID 3035>



Reverse
CCCGCTCGAG-ATCCTGCTCTTTTTTGCC <SEQ ID
XhoI




3036>


 


406
Forward
CGCGGATCCCATATG-TGCGGGACACTGACAG
BamHI-NdeI




<SEQ ID 3037>



Reverse
CCCGCTCGAG-AGGTTGTCCTTGTCTATG <SEQ
XhoI




ID 3038>









Localization of the ORFs

The following DNA and amino acid sequences are identified by titles of the following form: [g, m, or a] [#].[seq or pep], where “g” means a sequence from N. gonorrhoeae, “m” means a sequence from N. meningitidis B, and “a” means a sequence from N. meningitidis A; “#” means the number of the sequence; “seq” means a DNA sequence, and “pep” means an amino acid sequence. For example, “g001.seq” refers to an N. gonorrhoeae DNA sequence, number 1. The presence of the suffix “−1” to these sequences indicates an additional sequence found for the same ORF, thus, data for an ORF having both an unsuffixed and a suffixed sequence designation applies to both such designated sequences. Further, open reading frames are identified as ORF #, where “#” means the number of the ORF, corresponding to the number of the sequence which encodes the ORF, and the ORF designations may be suffixed with “.ng” or “.a”, indicating that the ORF corresponds to a N. gonorrhoeae sequence or a N. meningitidis A sequence, respectively. The word “partial” before a sequence indicates that the sequence may be partial or a complete ORF. Computer analysis was performed for the comparisons that follow between “g”, “m”, and “a” peptide sequences; and therein the “pep” suffix is implied where not expressly stated. Further, in the event of a conflict between the text immediately preceding and describing which sequences are being compared, and the designated sequences being compared, the designated sequence controls and is the actual sequence being compared
ORF: contig:
279 gnm4.seq
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3039>:









m279.seq




1
ATAACGCGGA TTTGCGGCTG CTTGATTTCA ACGGTTTTCA GGGCTTCGGC


 


51
AAGTTTGTCG GCGGCGGGTT TCATCAGGCT GCAATGGGAA GGTACGGACA


 


101
CGGGCAGCGG CAGGGCGCGT TTGGCACCGG CTTCTTTGGC GGCAGCCATG


 


151
GCGCGTCCGA CGGCGGCGGC GTTGCCTGCA ATCACGATTT GTCCGGGTGA


 


201
GTTGAAGTTG ACGGCTTCGA CCACTTCGCT TTGGGCGGCT TCGGCACAAA


 


251
TGGCTTTAAC CTGCTCATCT TCCAAGCCGA GAATCGCCGC CATTGCGCCC


 


301
ACGCCTTGCG GTACGGCGGA CTGCATCAGT TCGGCGCGCA GGCGCACGAG


 


351
TTTGACCGCG TCGGCAAAAT TCAATGCGCC GGCGGCAACG AGTGCGGTGT


 


401
ATTCGCCGAG GCTGTGTCCG GCAACGGCGG CAGGCGTTTT GCCGCCCGCT


 


451
TCTAAATAG






This corresponds to the amino acid sequence <SEQ ID 3040; ORF 279>:










m279.pep




1
ITRICGCLIS TVFRASASLS AAGFIRLQWE GTDTGSGRAR LAPASLAAAM


 


51
ARPTAAALPA ITICPGELKL TASTTSLWAA SAQMALTCSS SKPRIAAIAP


 


101
TPCGTADCIS SARRRTSLTA SAKFNAPAAT SAVYSPRLCP ATAAGVLPPA


 


151
SK*






The following partial DNA sequence was identified in N. gonorrhoeae<SEQ ID 3041>:










g279.seq




1
atgacgcgga tttgcggctg cttgatttca acggttttga gtgtttcggc


 


51
aagtttgtcg gcggcgggtt tcatcaggct gcaatgggaa ggaacggata


 


101
ccggcagcgg cagggcgcgt ttggctccgg cttctttggc ggcagccatg


 


151
gtgcgtccga cggcggcggc gttgcctgca atcacgactt gtccgggcga


 


201
gttgaagttg acggcttcga ccacttcgcc ctgtgcggat tcggcacaaa


 


251
tctgcctgac ctgttcatct tccaaaccca aaatggccgc cattgcgcct


 


301
acgccttgcg gtacggcgga ctgcatcagt tcggcgcgca ggcggacgag


 


351
tttgacggca tcggcaaaat ccaatgcttc ggcggcgaca agcgcggtgt


 


401
attcgccgag gctgtgtccg gcaacggcgg caggcgtttt gccgcccact


 


451
tccaaatag






This corresponds to the amino acid sequence <SEQ ID 3042; ORF 279.ng>:










g279.pep




1
MTRICGCLIS TVLSVSASLS AAGFIRLQWE GTDTGSGRAR LAPASLAAAM


 


51
VRPTAAALPA ITTCPGELKL TASTTSPCAD SAQICLTCSS SKPKMAAIAP


 


101
TPCGTADCIS SARRRTSLTA SAKSNASAAT SAVYSPRLCP ATAAGVLPPT


 


151
SK*






ORF 279 shows 89.5% identity over a 152 aa overlap with a predicted ORF (ORF 279.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3043>:










a279.seq




1
ATGACNCNGA TTTGCGGCTG CTTGATTTCA ACGGTTTNNA GGGCTTCGGC


 


51
GAGTTTGTCG GCGGCGGGTT TCATGAGGCT GCAATGGGAA GGTACNGACA


 


101
CNGGCAGCGG CAGGGCGCGT TTGGCGCCGG CTTCTTTGGC GGCAAGCATA


 


151
GCGCGCTCGA CGGCGGCGGC ATTGCCTGCA ATCACGACTT GTCCGGGCGA


 


201
GTTGAAGTTG ACGGCTTCAA CCACTTCATC CTGTGCGGAT TCGGCGCAAA


 


251
TTTGTTTTAC CTGTTCATCT TCCAAGCCGA GAATCGCCGC CATTGCGCCC


 


301
ACGCCTTGCG GTACGGCGGA CTGCATCAGT TCGGCGCGCA NGCGCACGAG


 


351
TTTGACCGCG TCGGCAAAAT CCAATGCGCC GGCGGCAACN AGTGCGGTGT


 


401
ATTCGCCGAN GCTGTGTCCG GCAACGGCGG CAGGCGTTTT GCCGCCCGCT


 


451
TCCGAATAG






This corresponds to the amino acid sequence <SEQ ID 3044; ORF 279.a>:










a279.pep




1
MTXICGCLIS TVXRASASLS AAGFMRLQWE GTDTGSGRAR LAPASLAASI


 


51
ARSTAAALPA ITTCPGELKL TASTTSSCAD SAQICFTCSS SKPRIAAIAP


 


101
TPCGTADCIS SARXRTSLTA SAKSNAPAAT SAVYSPXLCP ATAAGVLPPA


 


151
SE*






m279/a279 ORFs 279 and 279.a showed a 88.2% identity in 152 aa overlap





519 and 519-1 gnm7.seq

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3045>:









m519.seq (partial)










1
..TCCGTTATCG GGCGTATGGA GTTGGACAAA ACGTTTGAAG AACGCGACGA



 


51
  AATCAACAGT ACTGTTGTTG CGGCTTTGGA CGAGGCGGCC GGGgCTTgGG


 


101
  GTGTGAAGGT TTTGCGTTAT GAGATTAAAG ACTTGGTTCC GCCGCAAGAA


 


151
  ATCCTTCGCT CAATGCAGGC GCAAATTACT GCCGAACGCG AAAAACGCGC


 


201
  CCGTATCGCC GAATCCGAAG GTCGTAAAAT CGAACAAATC AACCTTGCCA


 


251
  GTGGTCAGCG CGAAGCCGAA ATCCAACAAT CCGAAGGCGA GGCTCAGGCT


 


301
  GCGGTCAATG CGTCAAATGC CGAGAAAATC GCCCGCATCA ACCGCGCCAA


 


351
  AGGTGAAGCG GAATCCTTGC GCCTTGTTGC CGAAGCCAAT GCCGAAGCCA


 


401
  TCCGTCAAAT TGCCGCCGCC CTTCAAACCC AAGGCGGTGC GGATGCGGTC


 


451
  AATCTGAAGA TTGCGGAACA ATACGTCGCT GCGTTCAACA ATCTTGCCAA


 


501
  AGAAAGCAAT ACGCTGATTA TGCCCGCCAA TGTTGCCGAC ATCGGCAGCC


 


551
  TGATTTCTGC CGGTATGAAA ATTATCGACA GCAGCAAAAC CGCCAAaTAA






This corresponds to the amino acid sequence <SEQ ID 3046; ORF 519>:









m519.pep (partial)










1
..SVIGRMELDK TFEERDEINS TVVAALDEAA GAWGVKVLRY EIKDLVPPQE



 


51
  ILRSMQAQIT AEREKRARIA ESEGRKIEQI NLASGQREAE IQQSEGEAQA


 


101
  AVNASNAEKI ARINRAKGEA ESLRLVAEAN AEAIRQIAAA LQTQGGADAV


 


151
  NLKIAEQYVA AFNNLAKESN TLIMPANVAD IGSLISAGMK IIDSSKTAK*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3047>:










g519.seq




1
atggaatttt tcattatctt gttggcagcc gtcgccgttt tcggcttcaa


 


51
atcctttgtc gtcatccccc agcaggaagt ccacgttgtc gaaaggctcg


 


101
ggcgtttcca tcgcgccctg acggccggtt tgaatatttt gattcccttt


 


151
atcgaccgcg tcgcctaccg ccattcgctg aaagaaatcc ctttagacgt


 


201
acccagccag gtctgcatca cgcgcgataa tacgcaattg actgttgacg


 


251
gcatcatcta tttccaagta accgatccca aactcgcctc atacggttcg


 


301
agcaactaca ttatggcaat tacccagctt gcccaaacga cgctgcgttc


 


351
cgttatcggg cgtatggagt tggacaaaac gtttgaagaa cgcgacgaaa


 


401
tcaacagtac cgtcgtctcc gccctcgatg aagccgccgg ggcttggggt


 


451
gtgaaagtcc tccgttacga aatcaaggat ttggttccgc cgcaagaaat


 


501
ccttcgcgca atgcaggcac aaattaccgc cgaacgcgaa aaacgcgccc


 


551
gtattgccga atccgaaggc cgtaaaatcg aacaaatcaa ccttgccagt


 


601
ggtcagcgtg aagccgaaat ccaacaatcc gaaggcgagg ctcaggctgc


 


651
ggtcaatgcg tccaatgccg agaaaatcgc ccgcatcaac cgcgccaaag


 


701
gcgaagcgga atccctgcgc cttgttgccg aagccaatgc cgaagccaac


 


751
cgtcaaattg ccgccgccct tcaaacccaa agcggggcgg atgcggtcaa


 


801
tctgaagatt gcgggacaat acgttaccgc gttcaaaaat cttgccaaag


 


851
aagacaatac gcggattaag cccgccaagg ttgccgaaat cgggaaccct


 


901
aattttcggc ggcatgaaaa attttcgcca gaagcaaaaa cggccaaata


 


951
a






This corresponds to the amino acid sequence <SEQ ID 3048; ORF 519.ng>:










g519.pep




1
MEFFIILLAA VAVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRA MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAN


 


251
RQIAAALQTQ SGADAVNLKI AGQYVTAFKN LAKEDNTRIK PAKVAEIGNP


 


301
NFRRHEKFSP EAKTAK*






ORF 519 shows 87.5% identity over a 200 aa overlap with a predicted ORF (ORF 519.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3049>:










a519.seq




1
ATGGAATTTT TCATTATCTT GCTGGCAGCC GTCGTTGTTT TCGGCTTCAA


 


51
ATCCTTTGTT GTCATCCCAC AGCAGGAAGT CCACGTTGTC GAAAGGCTCG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGCCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGACAA TACGCAGCTG ACTGTTGACG


 


251
GTATCATCTA TTTCCAAGTA ACCGACCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCGAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAAT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGCAC CGTCGTCTCC GCCCTCGATG AAGCCGCCGG AGCTTGGGGT


 


451
GTGAAGGTTT TGCGTTATGA GATTAAAGAC TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCTCA ATGCAGGCGC AAATTACTGC TGAACGCGAA AAACGCGCCC


 


551
GTATCGCCGA ATCCGAAGGT CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGCG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCAAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GTGAAGCGGA ATCCTTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGTGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTCGCCGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GTATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 3050; ORF 519.a>:










a519.pep




1
MEFFIILLAA VVVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRS MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






m519/a519 ORFs 519 and 519.a showed a 99.5% identity in 199 aa overlap




Further work revealed the DNA sequence identified in N. meningitidis <SEQ ID 3051>:










m519-1.seq




1
ATGGAATTTT TCATTATCTT GTTGGTAGCC GTCGCCGTTT TCGGTTTCAA


 


51
ATCCTTTGTT GTCATCCCAC AACAGGAAGT CCACGTTGTC GAAAGGCTGG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGcCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGACAA TACGCAGCTG ACTGTTGACG


 


251
GCATCATCTA TTTCCAAGTA ACCGACCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCGAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAGT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGTAC TGTTGTTGCG GCTTTGGACG AGGCGGCCGG GGCTTGGGGT


 


451
GTGAAGGTTT TGCGTTATGA GATTAAAGAC TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCTCA ATGCAGGCGC AAATTACTGC CGAACGCGAA AAACGCGCCC


 


551
GTATCGCCGA ATCCGAAGGT CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGCG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCAAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GTGAAGCGGA ATCCTTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGTGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTCGCTGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GTATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 3052; ORF 519-1>:










m519-1.




1
MEFFIILLVA VAVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVA ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRS MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3053>:










g519-1.seq




1
ATGGAATTTT TCATTATCTT GTTGGCAGCC GTCGCCGTTT TCGGCTTCAA


 


51
ATCCTTTGTC GTCATCCCCC AGCAGGAAGT CCACGTTGTC GAAAGGCTCG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGCCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGATAA TACGCAATTG ACTGTTGACG


 


251
GCATCATCTA TTTCCAAGTA ACCGATCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCAAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAGT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGTAC CGTCGTCTCC GCCCTCGATG AAGCCGCCGG GGCTTGGGGT


 


451
GTGAAAGTCC TCCGTTACGA AATCAAGGAT TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCGCA ATGCAGGCAC AAATTACCGC CGAACGCGAA AAACGCGCCC


 


551
GTATTGCCGA ATCCGAAGGC CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGTG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCCAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GCGAAGCGGA ATCCCTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGGGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTAGCCGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GCATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 3054; ORF 519-1.ng>:










g519-1.pep




1
MEFFIILLAA VAVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRA MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






m519-1/g519-1 99.0% identity in 315 aa overlap




The following DNA sequence was identified in N. meningitidis <SEQ ID 3055>:










a519-1.seq




1
ATGGAATTTT TCATTATCTT GCTGGCAGCC GTCGTTGTTT TCGGCTTCAA


 


51
ATCCTTTGTT GTCATCCCAC AGCAGGAAGT CCACGTTGTC GAAAGGCTCG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGCCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGACAA TACGCAGCTG ACTGTTGACG


 


251
GTATCATCTA TTTCCAAGTA ACCGACCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCGAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAAT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGCAC CGTCGTCTCC GCCCTCGATG AAGCCGCCGG AGCTTGGGGT


 


451
GTGAAGGTTT TGCGTTATGA GATTAAAGAC TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCTCA ATGCAGGCGC AAATTACTGC TGAACGCGAA AAACGCGCCC


 


551
GTATCGCCGA ATCCGAAGGT CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGCG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCAAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GTGAAGCGGA ATCCTTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGTGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTCGCCGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GTATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 3056; ORF 519-1.a>:










a519-1.pep.




1
MEFFIILLAA VVVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRS MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






m519-1/a519-1 ORFs 519-1 and 519-1.a showed a 99.0% identity in 315 aa overlap




576 and 576-1 gnm22.seq

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3057>:









m576.seq.. (partial)










1
..ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA



 


51
  GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


101
  CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


151
  GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


201
  AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


251
  TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


301
  CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


351
  CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


401
  TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


451
  GTGATTCCGG GTTGGACCGA AGgCGTACAG CTTCTGAAAG AAGGCGGCGA


 


501
  AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


551
  GCGACAAAAT CGGTCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


601
  AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


651
  CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 3058; ORF 576>:









m576.pep.. (partial)










1
..MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ



 


51
  AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


101
  LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


151
  VIPGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


201
  KIGAPENAPA KQPAQVDIKK VN*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3059>:









g576.seq.. (partial)










1
..atgggcgtgg acatcggacg ctccctgaaa caaatgaagg aacagggcgc



 


51
  ggaaatcgat ttgaaagtct ttaccgatgc catgcaggca gtgtatgacg


 


101
  gcaaagaaat caaaatgacc gaagagcagg cccaggaagt gatgatgaaa


 


151
  ttcctgcagg agcagcaggc taaagccgta gaaaaacaca aggcggatgc


 


201
  gaaggccaac aaagaaaaag gcgaagcctt cctgaaggaa aatgccgccg


 


251
  aagacggcgt gaagaccact gcttccggtc tgcagtacaa aatcaccaaa


 


301
  cagggtgaag gcaaacagcc gacaaaagac gacatcgtta ccgtggaata


 


351
  cgaaggccgc ctgattgacg gtaccgtatt cgacagcagc aaagccaacg


 


401
  gcggcccggc caccttccct ttgagccaag tgattccggg ttggaccgaa


 


451
  ggcgtacggc ttctgaaaga aggcggcgaa gccacgttct acatcccgtc


 


501
  caaccttgcc taccgcgaac agggtgcggg cgaaaaaatc ggtccgaacg


 


551
  ccactttggt atttgacgtg aaactggtca aaatcggcgc acccgaaaac


 


601
  gcgcccgcca agcagccgga tcaagtcgac atcaaaaaag taaattaa






This corresponds to the amino acid sequence <SEQ ID 3060; ORF 576.ng>:









g576.pep.. (partial)










1
..MGVDIGRSLK QMKEQGAEID LKVFTDAMQA VYDGKEIKMT EEQAQEVMMK



 


51
  FLQEQQAKAV EKHKADAKAN KEKGEAFLKE NAAEDGVKTT ASGLQYKITK


 


101
  QGEGKQPTKD DIVTVEYEGR LIDGTVFDSS KANGGPATFP LSQVIPGWTE


 


151
  GVRLLKEGGE ATFYIPSNLA YREQGAGEKI GPNATLVFDV KLVKIGAPEN


 


201
  APAKQPDQVD IKKVN*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m576/g576 97.2% identity in 215 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3061>:










a576.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC


 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTTCCGCG CAGGGCGACA CCTCTTCGAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


401
TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


451
CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


601
GTGATTCTGG GTTGGACCGA AGGCGTACAG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGACAAAAT CGGCCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 3062; ORF 576.a>:










a576.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASSA QGDTSSIGST


 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


201
VILGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPAQVDIKK VN*






m576/a576 99.5% identity in 222 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3063>:










m576-1.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC


 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTTCCGCG CAGGGCGACA CCTCTTCGAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


401
TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


451
CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


601
GTGATTCCGG GTTGGACCGA AGGCGTACAG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGACAAAAT CGGTCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 3064; ORF 576-1>:










m576-1.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASSA QGDTSSIGST


 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


201
VIPGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPAQVDIKK VN*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3065>:










g576-1.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC


 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTGCCGCG CAGGGCGACA CCTCTTCAAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC AATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
ACAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGATG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCCCAGGAAG TGATGATGAA ATTCCTGCAG GAGCAGCAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGATG CGAAGGCCAA CAAAGAAAAA GGCGAAGCCT


 


401
TCCTGAAGGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGT


 


451
CTGCAGTACA AAATCACCAA ACAGGGTGAA GGCAAACAGC CGACAAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACCGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG CCACCTTCCC TTTGAGCCAA


 


601
GTGATTCCGG GTTGGACCGA AGGCGTACGG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGAAAAAAT CGGTCCGAAC GCCACTTTGG TATTTGACGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG ATCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 3066; ORF 576-1.ng>:










g576-1.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASAA QGDTSSIGST


 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTDAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPATFPLSQ


 


201
VIPGWTEGVR LLKEGGEATF YIPSNLAYRE QGAGEKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPDQVDIKK VN*






g576-1/m576-1 ORFa 576-1 and 567-1.a showed a 97.8% identity in 272 aa overlap




The following DNA sequence was identified in N. meningitidis <SEQ ID 3067>:










a576-1.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC


 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTTCCGCG CAGGGCGACA CCTCTTCGAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


401
TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


451
CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


601
GTGATTCTGG GTTGGACCGA AGGCGTACAG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGACAAAAT CGGCCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 3068; ORF 576-1.a>:










a576-1.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASSA QGDTSSIGST


 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


201
VILGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPAQVDIKK VN*






a576-1/m576-1 99.6% identity in 272 aa overlap




919 gnm43.seq

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3069>:










m919.seq




1
ATGAAAAAAT ACCTATTCCG CGCCGCCCTG TACGGCATCG CCGCCGCCAT


 


51
CCTCGCCGCC TGCCAAAGCA AGAGCATCCA AACCTTTCCG CAACCCGACA


 


101
CATCCGTCAT CAACGGCCCG GACCGGCCGG TCGGCATCCC CGACCCCGCC


 


151
GGAACGACGG TCGGCGGCGG CGGGGCCGTC TATACCGTTG TACCGCACCT


 


201
GTCCCTGCCC CACTGGGCGG CGCAGGATTT CGCCAAAAGC CTGCAATCCT


 


251
TCCGCCTCGG CTGCGCCAAT TTGAAAAACC GCCAAGGCTG GCAGGATGTG


 


301
TGCGCCCAAG CCTTTCAAAC CCCCGTCCAT TCCTTTCAGG CAAAACAGTT


 


351
TTTTGAACGC TATTTCACGC CGTGGCAGGT TGCAGGCAAC GGAAGCCTTG


 


401
CCGGTACGGT TACCGGCTAT TACGAACCGG TGCTGAAGGG CGACGACAGG


 


451
CGGACGGCAC AAGCCCGCTT CCCGATTTAC GGTATTCCCG ACGATTTTAT


 


501
CTCCGTCCCC CTGCCTGCCG GTTTGCGGAG CGGAAAAGCC CTTGTCCGCA


 


551
TCAGGCAGAC GGGAAAAAAC AGCGGCACAA TCGACAATAC CGGCGGCACA


 


601
CATACCGCCG ACCTCTCCcG ATTCCCCATC ACCGCGCGCA CAACAGCAAT


 


651
CAAAGGCAGG TTTGAAGGAA GCCGCTTCCT CCCCTACCAC ACGCGCAACC


 


701
AAATCAACGG CGGCGCGCTT GACGGCAAAG CCCCGATACT CGGTTACGCC


 


751
GAAGACCCTG TCGAACTTTT TTTTATGCAC ATCCAAGGCT CGGGCCGTCT


 


801
GAAAACCCCG TCCGGCAAAT ACATCCGCAT CGGCTATGCC GACAAAAACG


 


851
AACATCCyTA CGTTTCCATC GGACGCTATA TGGCGGATAA GGGCTACCTC


 


901
AAACTCGGAC AAACCTCCAT GCAGGGCATT AAGTCTTATA TGCGGCAAAA


 


951
TCCGCAACGC CTCGCCGAAG TTTTGGGTCA AAACCCCAGC TATATCTTTT


 


1001
TCCGCGAGCT TGCCGGAAGC AGCAATGACG GCCCTGTCGG CGCACTGGGC


 


1051
ACGCCGCTGA TGGGGGAATA TGCCGGCGCA GTCGACCGGC ACTACATTAC


 


1101
CTTGGGTGCG CCCTTATTTG TCGCCACCGC CCATCCGGTT ACCCGCAAAG


 


1151
CCCTCAACCG CCTGATTATG GCGCAGGATA CCGGCAGCGC GATTAAAGGC


 


1201
GCGGTGCGCG TGGATTATTT TTGGGGATAC GGCGACGAAG CCGGCGAACT


 


1251
TGCCGGCAAA CAGAAAACCA CGGGATATGT CTGGCAGCTC CTACCCAACG


 


1301
GTATGAAGCC CGAATACCGc CCGTAA






This corresponds to the amino acid sequence <SEQ ID 3070; ORF 919>:










m919.pep




1
MKKYLFRAAL YGIAAAILAA CQSKSIQTFP QPDTSVINGP DRPVGIPDPA


 


51
GTTVGGGGAV YTVVPHLSLP HWAAQDFAKS LQSFRLGCAN LKNRQGWQDV


 


101
CAQAFQTPVH SFQAKQFFER YFTPWQVAGN GSLAGTVTGY YEPVLKGDDR


 


151
RTAQARFPIY GIPDDFISVP LPAGLRSGKA LVRIRQTGKN SGTIDNTGGT


 


201
HTADLSRFPI TARTTAIKGR FEGSRFLPYH TRNQINGGAL DGKAPILGYA


 


251
EDPVELFFMH IQGSGRLKTP SGKYIRIGYA DKNEHPYVSI GRYMADKGYL


 


301
KLGQTSMQGI KSYMRQNPQR LAEVLGQNPS YIFFRELAGS SNDGPVGALG


 


351
TPLMGEYAGA VDRHYITLGA PLFVATAHPV TRKALNRLIM AQDTGSAIKG


 


401
AVRVDYFWGY GDEAGELAGK QKTTGYVWQL LPNGMKPEYR P*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3071>:










g919.seq




1
ATGAAAAAAC ACCTGCTCCG CTCCGCCCTG TACGGcatCG CCGCCgccAT


 


51
CctcgCCGCC TGCCAAAgca gGAGCATCCA AACCTTTCCG CAACCCGACA


 


101
CATCCGTCAT CAACGGCCCG GACCGGCCGG CCGGCATCCC CGACCCCGCC


 


151
GGAACGACGG TTGCCGGCGG CGGGGCCGTC TATACCGTTG TGCCGCACCT


 


201
GTCCATGCCC CACTGGGCGG CGCaggATTT TGCCAAAAGC CTGCAATCCT


 


251
TCCGCCTCGG CTGCGCCAAT TTGAAAAACC GCCAAGGCTG GCAGGATGTG


 


301
TGCGCCCAAG CCTTTCAAAC CCCCGTGCAT TCCTTTCAGG CAAAGcGgTT


 


351
TTTTGAACGC TATTTCACGC cgtGGCaggt tgcaggcaAC GGAAGcCTTG


 


401
Caggtacggt TACCGGCTAT TACGAACCGG TGCTGAAGGG CGACGGCAGG


 


451
CGGACGGAAC GGGCCCGCTT CCCGATTTAC GGTATTCCCG ACGATTTTAT


 


501
CTCCGTCCCG CTGCCTGCCG GTTTGCGGGG CGGAAAAAAC CTTGTCCGCA


 


551
TCAGGCAGac ggGGAAAAAC AGCGGCACGA TCGACAATGC CGGCGGCACG


 


601
CATACCGCCG ACCTCTCCCG ATTCCCCATC ACCGCGCGCA CAACGGcaat


 


651
caaaGGCAGG TTTGAaggAA GCCGCTTCCT CCCTTACCAC ACGCGCAACC


 


701
AAAtcaacGG CGGCgcgcTT GACGGCAAag cccCCATCCT CggttacgcC


 


751
GAagaccCcG tcgaacttTT TTTCATGCAC AtccaaggCT CGGGCCGCCT


 


801
GAAAACCCcg tccggcaaat acatCCGCAt cggaTacgcc gacAAAAACG


 


851
AACAtccgTa tgtttccatc ggACGctaTA TGGCGGACAA AGGCTACCTC


 


901
AAGctcgggc agACCTCGAT GCAGGgcatc aaagcCTATA TGCGGCAAAA


 


951
TCCGCAACGC CTCGCCGAAG TTTTGGGTCA AAACCCCAGC TATATCTTTT


 


1001
TCCGCGAGCT TGCCGGAAGC GGCAATGAGG GCCCCGTCGG CGCACTGGGC


 


1051
ACGCCACTGA TGGGGGAATA CGCCGGCGCA ATCGACCGGC ACTACATTAC


 


1101
CTTGGGCGCG CCCTTATTTG TCGCCACCGC CCATCCGGTT ACCCGCAAAG


 


1151
CCCTCAACCG CCTGATTATG GCGCAGGATA CAGGCAGCGC GATCAAAGGC


 


1201
GCGGTGCGCG TGGATTATTT TTGGGGTTAC GGCGACGAAG CCGGCGAACT


 


1251
TGCCGGCAAA CAGAAAACCA CGGGATACGT CTGGCAGCTC CTGCCCAACG


 


1301
GCATGAAGCC CGAATACCGC CCGTGA






This corresponds to the amino acid sequence <SEQ ID 3072; ORF 919.ng>:










g919.pep




1
MKKHLLRSAL YGIAAAILAA CQSRSIQTFP QPDTSVINGP DRPAGIPDPA


 


51
GTTVAGGGAV YTVVPHLSMP HWAAQDFAKS LQSFRLGCAN LKNRQGWQDV


 


101
CAQAFQTPVH SFQAKRFFER YFTPWQVAGN GSLAGTVTGY YEPVLKGDGR


 


151
RTERARFPIY GIPDDFISVP LPAGLRGGKN LVRIRQTGKN SGTIDNAGGT


 


201
HTADLSRFPI TARTTAIKGR FEGSRFLPYH TRNQINGGAL DGKAPILGYA


 


251
EDPVELFFMH IQGSGRLKTP SGKYIRIGYA DKNEHPYVSI GRYMADKGYL


 


301
KLGQTSMQGI KAYMRQNPQR LAEVLGQNPS YIFFRELAGS GNEGPVGALG


 


351
TPLMGEYAGA IDRHYITLGA PLFVATAHPV TRKALNRLIM AQDTGSAIKG


 


401
AVRVDYFWGY GDEAGELAGK QKTTGYVWQL LPNGMKPEYR P*






ORF 919 shows 95.9% identity over a 441 aa overlap with a predicted ORF (ORF 919.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3073>:










a919.seq




1
ATGAAAAAAT ACCTATTCCG CGCCGCCCTG TGCGGCATCG CCGCCGCCAT


 


51
CCTCGCCGCC TGCCAAAGCA AGAGCATCCA AACCTTTCCG CAACCCGACA


 


101
CATCCGTCAT CAACGGCCCG GACCGGCCGG TCGGCATCCC CGACCCCGCC


 


151
GGAACGACGG TCGGCGGCGG CGGGGCCGTT TATACCGTTG TGCCGCACCT


 


201
GTCCCTGCCC CACTGGGCGG CGCAGGATTT CGCCAAAAGC CTGCAATCCT


 


251
TCCGCCTCGG CTGCGCCAAT TTGAAAAACC GCCAAGGCTG GCAGGATGTG


 


301
TGCGCCCAAG CCTTTCAAAC CCCCGTCCAT TCCGTTCAGG CAAAACAGTT


 


351
TTTTGAACGC TATTTCACGC CGTGGCAGGT TGCAGGCAAC GGAAGCCTTG


 


401
CCGGTACGGT TACCGGCTAT TACGAGCCGG TGCTGAAGGG CGACGACAGG


 


451
CGGACGGCAC AAGCCCGCTT CCCGATTTAC GGTATTCCCG ACGATTTTAT


 


501
CTCCGTCCCC CTGCCTGCCG GTTTGCGGAG CGGAAAAGCC CTTGTCCGCA


 


551
TCAGGCAGAC GGGAAAAAAC AGCGGCACAA TCGACAATAC CGGCGGCACA


 


601
CATACCGCCG ACCTCTCCCA ATTCCCCATC ACTGCGCGCA CAACGGCAAT


 


651
CAAAGGCAGG TTTGAAGGAA GCCGCTTCCT CCCCTACCAC ACGCGCAACC


 


701
AAATCAACGG CGGCGCGCTT GACGGCAAAG CCCCGATACT CGGTTACGCC


 


751
GAAGACCCCG TCGAACTTTT TTTTATGCAC ATCCAAGGCT CGGGCCGTCT


 


801
GAAAACCCCG TCCGGCAAAT ACATCCGCAT CGGCTATGCC GACAAAAACG


 


851
AACATCCCTA CGTTTCCATC GGACGCTATA TGGCGGACAA AGGCTACCTC


 


901
AAGCTCGGGC AGACCTCGAT GCAGGGCATC AAAGCCTATA TGCAGCAAAA


 


951
CCCGCAACGC CTCGCCGAAG TTTTGGGGCA AAACCCCAGC TATATCTTTT


 


1001
TCCGAGAGCT TACCGGAAGC AGCAATGACG GCCCTGTCGG CGCACTGGGC


 


1051
ACGCCGCTGA TGGGCGAGTA CGCCGGCGCA GTCGACCGGC ACTACATTAC


 


1101
CTTGGGCGCG CCCTTATTTG TCGCCACCGC CCATCCGGTT ACCCGCAAAG


 


1151
CCCTCAACCG CCTGATTATG GCGCAGGATA CCGGCAGCGC GATTAAAGGC


 


1201
GCGGTGCGCG TGGATTATTT TTGGGGATAC GGCGACGAAG CCGGCGAACT


 


1251
TGCCGGCAAA CAGAAAACCA CGGGATATGT CTGGCAGCTT CTGCCCAACG


 


1301
GTATGAAGCC CGAATACCGC CCGTAA






This corresponds to the amino acid sequence <SEQ ID 3074; ORF 919.a>:










a919.pep




1
MKKYLFRAAL CGIAAAILAA CQSKSIQTFP QPDTSVINGP DRPVGIPDPA


 


51
GTTVGGGGAV YTVVPHLSLP HWAAQDFAKS LQSFRLGCAN LKNRQGWQDV


 


101
CAQAFQTPVH SVQAKQFFER YFTPWQVAGN GSLAGTVTGY YEPVLKGDDR


 


151
RTAQARFPIY GIPDDFISVP LPAGLRSGKA LVRIRQTGKN SGTIDNTGGT


 


201
HTADLSQFPI TARTTAIKGR FEGSRFLPYH TRNQINGGAL DGKAPILGYA


 


251
EDPVELFFMH IQGSGRLKTP SGKYIRIGYA DKNEHPYVSI GRYMADKGYL


 


301
KLGQTSMQGI KAYMQQNPQR LAEVLGQNPS YIFFRELTGS SNDGPVGALG


 


351
TPLMGEYAGA VDRHYITLGA PLFVATAHPV TRKALNRLIM AQDTGSAIKG


 


401
AVRVDYFWGY GDEAGELAGK QKTTGYVWQL LPNGMKPEYR P*






m919/a919 98.6% identity in 441 aa overlap





121 and 121-1

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3075>:










m121.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CCAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC AGACGAACTG CACCGCAGCA GGATTTTGTC


 


201
GCAAGAACTC AGCCGCCTAT ATGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCACCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCCGAC ACGCGCCGGA ACACGGTTAC AGCATACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


401
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


451
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


501
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


551
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


601
xxxxxxCAGC TTCCTTACGA CAAAAACGGT GCAAAGTCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACGCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCAT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGTTTT ACCGCGCAAA CCGTTTGCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGACG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAC CTGAACCTCG ATCCGCAATG GGTGGAAGCC GCCGnATTTG


 


1001
CGTGGTTGGC GGCGTGTTGG ATTAATCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG AnCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 3076; ORF 121>:










m121.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRQLL


 


51
DLQDTGADEL HRSRILSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHGY SIQLADLPLL Axxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


151
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


201
xxQLPYDKNG AKSAQGNILP QLLDRLLAHP YFAQRHPKST GRELFAINWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVCDAVS HAAADARQMY ICDGGIRNPV


 


301
LMADLAECFG TRVSLHSTAD LNLDPQWVEA AXFAWLAACW INRIPGSPHK


 


351
ATGASKPCIL XAGYYY*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3077>:










g121.seq




1
ATGGAAACAC AGCTTTACAT CGGCATTATG TCGGGAACCA GTATGGACGG


 


51
GGCGGATGCC GTGCTGGTAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCTGACC GGTTGCGCCG CAAATTGCTG


 


151
GATTTGCAGG ACACAGGCAC AGACGAACTG CACCGCAGCA GGATGTTGTC


 


201
GCAAGAACTC AGCCGCCTGT ACGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCTCCGTGC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCCGAC ACGCGCCGGA ACACGGTtac AGCATACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACTGa cgcggatttT TACCGTCggc gacttcCGCA


 


401
GCCGCGACCT TGCTGCCGGC GGacaAGGTG CGCCGCTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA TGACAGGGAA ACACGCGTGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGGCGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGGCCGGGC AATATGCTGA TGGAcgcgtg gacgcaggca


 


601
cacTGGcagc TGCCTTACGA CAAAAacggt gcAAAGgcgg cacAAGGCAA


 


651
catatTGCcg cAACTGCTCG gcaggctGCT CGCCcaccCG TATTTCTCAC


 


701
AACCCcaccc aaAAAGCACG GGgcGCGaac TgtttgcccT AAattggctc


 


751
gaaacctAcc ttgacggcgg cgaaaaccga tacgacgtat tgcggacgct


 


801
ttcccgattc accgcgcaaA ccgTttggga cgccgtctca CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAA CTGAACCTCG ATCCTCAATG GGTGGAGGCG gccgCATTtg


 


1001
cgtggttggC GGCGTGTTGG ATTAACCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCGACCGGCG CATCCAAACC GTGTATTCTG GGCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 3078; ORF 121.ng>:










g121.pep




1
METQLYIGIM SGTSMDGADA VLVRMDGGKW LGAEGHAFTP YPDRLRRKLL


 


51
DLQDTGTDEL HRSRMLSQEL SRLYAQTAAE LLCSQNLAPC DITALGCHGQ


 


101
TVRHAPEHGY SIQLADLPLL AELTRIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDDRE TRVVLNIGGI ANISVLPPGA PAFGFDTGPG NMLMDAWTQA


 


201
HWQLPYDKNG AKAAQGNILP QLLGRLLAHP YFSQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVWDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAE LNLDPQWVEA AAFAWLAACW INRIPGSPHK


 


351
ATGASKPCIL GAGYYY*






ORF 121 shows 73.5% identity over a 366 aa overlap with a predicted ORF (ORF121.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3079>:










a121.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CAAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC GGACGAACTG CACCGCAGCA GGATGTTGTC


 


201
GCAAGAACTC AGCCGCCTGT ACGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCGCCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCAGAC ACGCGCCGGA ACACAGTTAC AGCGTACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACGGA CTCAGATTTT TACCGTCGGC GACTTCCGCA


 


401
GCCGCGACCT TGCGGCCGGC GGACAAGGCG CGCCGCTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA CGACAGGGAA ACACGCGCGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGACGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGACCGGGC AATATGCTGA TGGACGCGTG GATGCAGGCA


 


601
CACTGGCAGC TTCCTTACGA CAAAAACGGT GCAAAGGCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACCCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCCT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGATTC ACCGCGCAAA CCGTTTTCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAA CTGAACCTCG ATCCGCAATG GGTAGAAGCC GCCGCGTTCG


 


1001
CATGGATGGC GGCGTGTTGG GTCAACCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG GGCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 3080; ORF 121.a>:










a121.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRKLL


 


51
DLQDTGADEL HRSRMLSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHSY SVQLADLPLL AERTQIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDDRE TRAVLNIGGI ANISVLPPDA PAFGFDTGPG NMLMDAWMQA


 


201
HWQLPYDKNG AKAAQGNILP QLLDRLLAHP YFAQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVFDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAE LNLDPQWVEA AAFAWMAACW VNRIPGSPHK


 


351
ATGASKPCIL GAGYYY*






m121/a121 74.0% identity in 366 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3081>:










m121-1.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CCAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC AGACGAACTG CACCGCAGCA GGATTTTGTC


 


201
GCAAGAACTC AGCCGCCTAT ATGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCACCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCCGAC ACGCGCCGGA ACACGGTTAC AGCATACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACGGA CGCGGATTTT TACCGTCGGC GACTTCCGCA


 


401
GCCGCGACCT TGCGGCCGGC GGACAAGGCG CGCCACTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA CAACAGGGAA ACACGCGCGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGACGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGGCCGGGC AATATGCTGA TGGACGCGTG GACGCAGGCA


 


601
CACTGGCAGC TTCCTTACGA CAAAAACGGT GCAAAGGCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACCCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCCT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGTTTT ACCGCGCAAA CCGTTTGCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAC CTGAACCTCG ATCCGCAATG GGTGGAAGCC GCCGNATTTG


 


1001
CGTGGTTGGC GGCGTGTTGG ATTAATCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG ANCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 3082; ORF 121-1>:










m121-1.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRQLL


 


51
DLQDTGADEL HRSRILSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHGY SIQLADLPLL AERTRIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDNRE TRAVLNIGGI ANISVLPPDA PAFGFDTGPG NMLMDAWTQA


 


201
HWQLPYDKNG AKAAQGNILP QLLDRLLAHP YFAQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVCDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAD LNLDPQWVEA AXFAWLAACW INRIPGSPHK


 


351
ATGASKPCIL XAGYYY*






m121-1/g121 95.6% identity in 366 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3083>:










a121-1.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CAAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC GGACGAACTG CACCGCAGCA GGATGTTGTC


 


201
GCAAGAACTC AGCCGCCTGT ACGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCGCCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCAGAC ACGCGCCGGA ACACAGTTAC AGCGTACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACGGA CTCAGATTTT TACCGTCGGC GACTTCCGCA


 


401
GCCGCGACCT TGCGGCCGGC GGACAAGGCG CGCCGCTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA CGACAGGGAA ACACGCGCGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGACGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGACCGGGC AATATGCTGA TGGACGCGTG GATGCAGGCA


 


601
CACTGGCAGC TTCCTTACGA CAAAAACGGT GCAAAGGCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACCCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCCT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGATTC ACCGCGCAAA CCGTTTTCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAA CTGAACCTCG ATCCGCAATG GGTAGAAGCC GCCGCGTTCG


 


1001
CATGGATGGC GGCGTGTTGG GTCAACCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG GGCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 3084; ORF 121-1.a>:










a121-1.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRKLL


 


51
DLQDTGADEL HRSRMLSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHSY SVQLADLPLL AERTQIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDDRE TRAVLNIGGI ANISVLPPDA PAFGFDTGPG NMLMDAWMQA


 


201
HWQLPYDKNG AKAAQGNILP QLLDRLLAHP YFAQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVFDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAE LNLDPQWVEA AAFAWMAACW VNRIPGSPHK


 


351
ATGASKPCIL GAGYYY*






m121-1/a121-1 96.4% identity in 366 aa overlap




128 and 128-1

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3085>:









m128.seq (partial)










1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATCGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTGCGTCGC CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCCGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTCGAC ACCCTCTCCC CCGCACAAAA AACCAAACTC AACCAC


 


1
TACGCCAGCG AAAAACTGCG CGAAGCCAAA TACGCGTTCA GCGAAACCGA


 


51
wGTCAAAAAA TAyTTCCCyG TCGGCAAwGT ATTAAACGGA CTGTTCGCCC


 


101
AAmTCAAAAA ACTmTACGGC ATCGGATTTA CCGAAAAAAC yGTCCCCGTC


 


151
TGGCACAAAG ACGTGCGCTA TTkTGAATTG CAACAAAACG GCGAAmCCAT


 


201
AGGCGGCGTT TATATGGATT TGTACGCACG CGAAGGCAAA CGCGGCGGCG


 


251
CGTGGATGAA CGACTACAAA GGCCGCCGCC GTTTTTCAGA CGGCACGCTG


 


301
CAAyTGCCCA CCGCCTACCT CGTCTGCAAC TTCGCCCCAC CCGTCGGCGG


 


351
CAGGGAAGCC CGCyTGAGCC ACGACGAAAT CCTCATCCTC TTCCACGAAA


 


401
CCGGACACGG GCTGCACCAC CTGCTTACCC AAGTGGACGA ACTGGGCGTA


 


451
TCCGGCATCA ACGGCGTAkA ATGGGACGCG GTCGAACTGC CCAGCCAGTT


 


501
TATGGAAAAT TTCGTTTGGG AATACAATGT CTTGGCACAA mTGTCAGCCC


 


551
ACGAAGAAAC CGGcgTTCCC yTGCCGAAAG AACTCTTsGA CAAAwTGCTC


 


601
GCCGCCAAAA ACTTCCAAsG CGGCATGTTC yTsGTCCGGC AAwTGGAGTT


 


651
CGCCCTCTTT GATATGATGA TTTACAGCGA AGACGACGAA GGCCGTCTGA


 


701
AAAACTGGCA ACAGGTTTTA GACAGCGTGC GCAAAAAAGT CGCCGTCATC


 


751
CAGCCGCCCG AATACAACCG CTTCGCCTTG AGCTTCGGCC ACATCTTCGC


 


801
AGGCGGCTAT TCCGCAGCTn ATTACAGCTA CGCGTGGGCG GAAGTATTGA


 


851
GCGCGGACGC ATACGCCGCC TTTGAAGAAA GCGACGATGT CGCCGCCACA


 


901
GGCAAACGCT TTTGGCAGGA AATCCTCGCC GTCGGGGnAT CGCGCAGCGG


 


951
nGCAGAATCC TTCAAAGCCT TCCGCGGCCG CGAACCGAGC ATAGACGCAC


 


1001
TCTTGCGCCA CAGCGGTTTC GACAACGCGG TCTGA






This corresponds to the amino acid sequence <SEQ ID 3086; ORF 128>:









m128.pep (partial)










1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA



 


51
NTVEPLTGIT ERVGRIWGVV SHLNCVADTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSPAQKTKL NH


 








//










1
YASEKLREAK YAFSETXVKK YFPVGXVLNG LFAQXKKLYG IGFTEKTVPV



 


51
WHKDVRYXEL QQNGEXIGGV YMDLYAREGK RGGAWMNDYK GRRRFSDGTL


 


101
QLPTAYLVCN FAPPVGGREA RLSHDEILIL FHETGHGLHH LLTQVDELGV


 


151
SGINGVXWDA VELPSQFMEN FVWEYNVLAQ XSAHEETGVP LPKELXDKXL


 


201
AAKNFQXGMF XVRQXEFALF DMMIYSEDDE GRLKNWQQVL DSVRKKVAVI


 


251
QPPEYNRFAL SFGHIFAGGY SAAXYSYAWA EVLSADAYAA FEESDDVAAT


 


301
GKRFWQEILA VGXSRSGAES FKAFRGREPS IDALLRHSGF DNAV*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3087>:










g128.seq




1
atgattgaca acgCActgct ccacttgggc gaagaaccCC GTTTTaatca


 


51
aatccaaacc gaagACAtca AACCCGCCGT CCAAACCGCC ATCGCCGAAG


 


101
CGCGCGGACA AATCGCCGCC GTCAAAGCGC AAACGCACAC CGGCTGGGCG


 


151
AACACCGTCG AGCGTCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTCGTG TCCCATCTCA ACTCCGTCGT CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCTGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAACTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTTGCA ACGCTTTCCC CCGCACAAAA AACCAAGCTC GATCACGACC


 


401
TGCGCGATTT CGTATTGAGC GGCGCGGAAC TGCCGCCCGA ACGGCAGGCA


 


451
GAACTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCC


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGTTAC AAAATCGGCT TGCAGATTCC


 


651
GCACTACCTT GCCGTTATCC AATACGCCGG CAACCGCGAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGTGCCA GCGAACTTTC AAACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCATTGAA


 


801
AACCGccaaa cTGCTCGGCT TTAAAAATTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACGCCC GAACAGGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAACACCTCG GTCTCGCCGA CCCGCAGCCG TGGGACTTGA


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTTCTGGCAG GCCTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT CGCCGAAAAA ACCGTTCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCAAAACC


 


1201
ATCGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACtaca AAGGCCGCCG CCGCTTTGCC GACGgcacGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCGCCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CGCGTTTAAG CCACGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AacCGGCCAC GGACTGCACC ACCTGCTTAC CCAAGTGGAC GAACTGGGCG


 


1451
TGTCCGGCAT CAAcggcgtA GAATGGGACG CGGTCGAACT GCCCAGCCAG


 


1501
TTTATGGAAA ACTTCGTTTG GGAATACAAT GTATTGGCAC AAATGTCCGC


 


1551
CCACGAAGAA AccgGCGAGC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TcgcCGCCAA AAACTTCCAG CGCGGTATGT TCCTCGTCCG GCAAATGGAG


 


1651
TTCGCCCTCT TCGATATGAT GATTTACAGT GAAAGCGACG AATGCCGTCT


 


1701
GAAAAACTGG CAGCAGGTTT TAGACAGCGT GCGCAAAGAA GTcGCCGTCA


 


1751
TCCAACCGCC CGAATACAAC CGCTTCGCCA ACAGCTTCGG CCacatctTC


 


1801
GCcggcGGCT ATTCCGCAGG CTATTACAGC TACGCATGGG CCGAAGTCCt


 


1851
cAGCACCGAT GCCTACGCCG CCTTTGAAGA AAGcGACGac gtcGCCGCCA


 


1901
CAGGCAAACG CTTCTGGCAA GAAAtccttg ccgtcggcgg ctCCCGCAGC


 


1951
gcgGCGGAAT CCTTCAAAGC CTTCCGCGGA CGCGAACCGA GCATAGACGC


 


2001
ACTGCTGCGC CAaagcggtT TCGACAACGC gGCttgA






This corresponds to the amino acid sequence <SEQ ID 3088; ORF 128.ng>:










g128.pep




1
MIDNALLHLG EEPRFNQIQT EDIKPAVQTA IAEARGQIAA VKAQTHTGWA


 


51
NTVERLTGIT ERVGRIWGVV SHLNSVVDTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFA TLSPAQKTKL DHDLRDFVLS GAELPPERQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYAGNRE LREQIYRAYV TRASELSNDG


 


251
KFDNTANIDR TLENALKTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR EHLGLADPQP WDLSYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLAGLFAQIK KLYGIGFAEK TVPVWHKDVR YFELQQNGKT


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFA DGTLQLPTAY LVCNFAPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGEPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS ESDECRLKNW QQVLDSVRKE VAVIQPPEYN RFANSFGHIF


 


601
AGGYSAGYYS YAWAEVLSTD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR QSGFDNAA*






ORF 128 shows 91.7% identity over a 475 aa overlap with a predicted ORF (ORF 128.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3089>:










a128.seq




1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA


 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATTGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTCCGTCAC CGACACGCCC GAACTGCGCG


 


251
CCGCCTACAA TGAATTAATG CCCGAAATTA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAACTCCCC


 


351
CGAGTTCGAC ACCCTCTCCC ACGCGCAAAA AACCAAACTC AACCACGATC


 


401
TGCGCGATTT CGTCCTCAGC GGCGCGGAAC TGCCGCCCGA ACAGCAGGCA


 


451
GAATTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCT


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGCTAC AAAATCGGTT TGCAGATTCC


 


651
GCACTACCTC GCCGTCATCC AATACGCCGA CAACCGCAAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGCGCCA GCGAGCTTTC AGACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCCCTGCA


 


801
AACCGCCAAA CTGCTCGGCT TCAAAAACTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACCCCC GAACAAGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAAAGCCTCG GCCTCGCCGA TTTGCAACCG TGGGACTTGG


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTATTAAACG GACTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT TACCGAAAAA ACCGTCCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCGAAACC


 


1201
ATAGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGTTTTTCA GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCACCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CCCGCTTGAG CCATGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AACCGGACAC GGCCTGCACC ACCTGCTTAC CCAAGTCGAC GAACTGGGCG


 


1451
TATCCGGCAT CAACGGCGTA GAATGGGACG CAGTCGAACT GCCCAGTCAG


 


1501
TTTATGGAAA ATTTCGTTTG GGAATACAAT GTCTTGGCGC AAATGTCCGC


 


1551
CCACGAAGAA ACCGGCGTTC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TCGCCGCCAA AAACTTCCAA CGCGGAATGT TCCTCGTCCG CCAAATGGAG


 


1651
TTCGCCCTCT TTGATATGAT GATTTACAGC GAAGACGACG AAGGCCGTCT


 


1701
GAAAAACTGG CAACAGGTTT TAGACAGCGT GCGCAAAGAA GTCGCCGTCG


 


1751
TCCGACCGCC CGAATACAAC CGCTTCGCCA ACAGCTTCGG CCACATCTTC


 


1801
GCAGGCGGCT ATTCCGCAGG CTATTACAGC TACGCGTGGG CGGAAGTATT


 


1851
GAGCGCGGAC GCATACGCCG CCTTTGAAGA AAGCGACGAT GTCGCCGCCA


 


1901
CAGGCAAACG CTTTTGGCAG GAAATCCTCG CCGTCGGCGG ATCGCGCAGC


 


1951
GCGGCAGAAT CCTTCAAAGC CTTCCGCGGA CGCGAACCGA GCATAGACGC


 


2001
ACTCTTGCGC CACAGCGGCT TCGACAACGC GGCTTGA






This corresponds to the amino acid sequence <SEQ ID 3090; ORF 128.a>:










a128.pep




1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA


 


51
NTVEPLTGIT ERVGRIWGVV SHLNSVTDTP ELRAAYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSHAQKTKL NHDLRDFVLS GAELPPEQQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYADNRK LREQIYRAYV TRASELSDDG


 


251
KFDNTANIDR TLENALQTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR ESLGLADLQP WDLGYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLNGLFAQIK KLYGIGFTEK TVPVWHKDVR YFELQQNGET


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFS DGTLQLPTAY LVCNFTPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGVPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS EDDEGRLKNW QQVLDSVRKE VAVVRPPEYN RFANSFGHIF


 


601
AGGYSAGYYS YAWAEVLSAD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR HSGFDNAA*






m128/a128 66.0% identity in 677 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3091>:










m128-1.seq




1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA


 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATCGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTCCGTCGC CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCCGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTCGAC ACCCTCTCCC CCGCACAAAA AACCAAACTC AACCACGATC


 


401
TGCGCGATTT CGTCCTCAGC GGCGCGGAAC TGCCGCCCGA ACAGCAGGCA


 


451
GAACTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCC


 


601
GCCGCGCAAA GCGAAAGCAA AACAGGCTAC AAAATCGGCT TGCAGATTCC


 


651
ACACTACCTC GCCGTCATCC AATACGCCGA CAACCGCGAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGCGCCA GCGAACTTTC AGACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGCAA ACGCCCTGCA


 


801
AACCGCCAAA CTGCTCGGCT TCAAAAACTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACGCCC GAACAAGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAAAGCCTGA ACCTCGCCGA TTTGCAACCG TGGGACTTGG


 


1001
GCTACGCCAG CGAAAAACTG CGCGAAGCCA AATACGCGTT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTATTAAACG GACTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT TACCGAAAAA ACCGTCCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCGAAACC


 


1201
ATAGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGTTTTTCA GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCGCCCC ACCCGTCGGC


 


1351
GGCAGGGAAG CCCGCCTGAG CCACGACGAA ATCCTCATCC TCTTCCACGA


 


1401
AACCGGACAC GGGCTGCACC ACCTGCTTAC CCAAGTGGAC GAACTGGGCG


 


1451
TATCCGGCAT CAACGGCGTA GAATGGGACG CGGTCGAACT GCCCAGCCAG


 


1501
TTTATGGAAA ATTTCGTTTG GGAATACAAT GTCTTGGCAC AAATGTCAGC


 


1551
CCACGAAGAA ACCGGCGTTC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TCGCCGCCAA AAACTTCCAA CGCGGCATGT TCCTCGTCCG GCAAATGGAG


 


1651
TTCGCCCTCT TTGATATGAT GATTTACAGC GAAGACGACG AAGGCCGTCT


 


1701
GAAAAACTGG CAACAGGTTT TAGACAGCGT GCGCAAAAAA GTCGCCGTCA


 


1751
TCCAGCCGCC CGAATACAAC CGCTTCGCCT TGAGCTTCGG CCACATCTTC


 


1801
GCAGGCGGCT ATTCCGCAGG CTATTACAGC TACGCGTGGG CGGAAGTATT


 


1851
GAGCGCGGAC GCATACGCCG CCTTTGAAGA AAGCGACGAT GTCGCCGCCA


 


1901
CAGGCAAACG CTTTTGGCAG GAAATCCTCG CCGTCGGCGG ATCGCGCAGC


 


1951
GCGGCAGAAT CCTTCAAAGC CTTCCGCGGC CGCGAACCGA GCATAGACGC


 


2001
ACTCTTGCGC CACAGCGGTT TCGACAACGC GGTCTGA






This corresponds to the amino acid sequence <SEQ ID 3092; ORF 128-1>:










m128-1.pep.




1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA


 


51
NTVEPLTGIT ERVGRIWGVV SHLNSVADTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSPAQKTKL NHDLRDFVLS GAELPPEQQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSESKTGY KIGLQIPHYL AVIQYADNRE LREQIYRAYV TRASELSDDG


 


251
KFDNTANIDR TLANALQTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR ESLNLADLQP WDLGYASEKL REAKYAFSET


 


351
EVKKYFPVGK VLNGLFAQIK KLYGIGFTEK TVPVWHKDVR YFELQQNGET


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFS DGTLQLPTAY LVCNFAPPVG


 


451
GREARLSHDE ILILFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGVPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS EDDEGRLKNW QQVLDSVRKK VAVIQPPEYN RFALSFGHIF


 


601
AGGYSAGYYS YAWAEVLSAD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR HSGFDNAV*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3093>:









g128-1.seq (partial)










1
ATGATTGACA ACGCACTGCT CCACTTGGGC GAAGAACCCC GTTTTAATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCGT CCAAACCGCC ATCGCCGAAG


 


101
CGCGCGGACA AATCGCCGCC GTCAAAGCGC AAACGCACAC CGGCTGGGCG


 


151
AACACCGTCG AGCGTCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTCGTG TCCCATCTCA ACTCCGTCGT CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCTGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAACTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTTGCA ACGCTTTCCC CCGCACAAAA AACCAAGCTC GATCACGACC


 


401
TGCGCGATTT CGTATTGAGC GGCGCGGAAC TGCCGCCCGA ACGGCAGGCA


 


451
GAACTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCC


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGTTAC AAAATCGGCT TGCAGATTCC


 


651
GCACTACCTT GCCGTTATCC AATACGCCGG CAACCGCGAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGTGCCA GCGAACTTTC AAACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCATTGAA


 


801
AACCGCCAAA CTGCTCGGCT TTAAAAATTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACGCCC GAACAGGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAACACCTCG GTCTCGCCGA CCCGCAGCCG TGGGACTTGA


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTTCTGGCAG GCCTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT CGCCGAAAAA ACCGTTCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCAAAACC


 


1201
ATCGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGCTTTGCC GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCGCCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CGCGTTTAAG CCACGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AACCGGCCAC GGACTGCACC ACCTGCTTAC CCAAGTGGAC GAACTGGGCG


 


1451
TGTCCGGCAT CAACGGCGTA AAA






This corresponds to the amino acid sequence <SEQ ID 3094; ORF 128-1.ng>:










g128-1.pep
(partial)










1
MIDNALLHLG EEPRFNQIKT EDIKPAVQTA IAEARGQIAA VKAQTHTGWA



 


51
NTVERLTGIT ERVGRIWGVV SHLNSVVDTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFA TLSPAQKTKL DHDLRDFVLS GAELPPERQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYAGNRE LREQIYRAYV TRASELSNDG


 


251
KFDNTANIDR TLENALKTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR EHLGLADPQP WDLSYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLAGLFAQIK KLYGIGFAEK TVPVWHKDVR YFELQQNGKT


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFA DGTLQLPTAY LVCNFAPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV K






m128-1/g128-1 94.5% identity in 491 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3095>:










a128-1.seq




1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA


 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATTGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTCCGTCAC CGACACGCCC GAACTGCGCG


 


251
CCGCCTACAA TGAATTAATG CCCGAAATTA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAACTCCCC


 


351
CGAGTTCGAC ACCCTCTCCC ACGCGCAAAA AACCAAACTC AACCACGATC


 


401
TGCGCGATTT CGTCCTCAGC GGCGCGGAAC TGCCGCCCGA ACAGCAGGCA


 


451
GAATTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCT


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGCTAC AAAATCGGTT TGCAGATTCC


 


651
GCACTACCTC GCCGTCATCC AATACGCCGA CAACCGCAAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGCGCCA GCGAGCTTTC AGACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCCCTGCA


 


801
AACCGCCAAA CTGCTCGGCT TCAAAAACTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACCCCC GAACAAGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAAAGCCTCG GCCTCGCCGA TTTGCAACCG TGGGACTTGG


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTATTAAACG GACTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT TACCGAAAAA ACCGTCCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCGAAACC


 


1201
ATAGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGTTTTTCA GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCACCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CCCGCTTGAG CCATGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AACCGGACAC GGCCTGCACC ACCTGCTTAC CCAAGTCGAC GAACTGGGCG


 


1451
TATCCGGCAT CAACGGCGTA GAATGGGACG CAGTCGAACT GCCCAGTCAG


 


1501
TTTATGGAAA ATTTCGTTTG GGAATACAAT GTCTTGGCGC AAATGTCCGC


 


1551
CCACGAAGAA ACCGGCGTTC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TCGCCGCCAA AAACTTCCAA CGCGGAATGT TCCTCGTCCG CCAAATGGAG


 


1651
TTCGCCCTCT TTGATATGAT GATTTACAGC GAAGACGACG AAGGCCGTCT


 


1701
GAAAAACTGG CAACAGGTTT TAGACAGCGT GCGCAAAGAA GTCGCCGTCG


 


1751
TCCGACCGCC CGAATACAAC CGCTTCGCCA ACAGCTTCGG CCACATCTTC


 


1801
GCAGGCGGCT ATTCCGCAGG CTATTACAGC TACGCGTGGG CGGAAGTATT


 


1851
GAGCGCGGAC GCATACGCCG CCTTTGAAGA AAGCGACGAT GTCGCCGCCA


 


1901
CAGGCAAACG CTTTTGGCAG GAAATCCTCG CCGTCGGCGG ATCGCGCAGC


 


1951
GCGGCAGAAT CCTTCAAAGC CTTCCGCGGA CGCGAACCGA GCATAGACGC


 


2001
ACTCTTGCGC CACAGCGGCT TCGACAACGC GGCTTGA






This corresponds to the amino acid sequence <SEQ ID 3096; ORF 128-1.a>:










a128-1.pep




1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA


 


51
NTVEPLTGIT ERVGRIWGVV SHLNSVTDTP ELRAAYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSHAQKTKL NHDLRDFVLS GAELPPEQQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYADNRK LREQIYRAYV TRASELSDDG


 


251
KFDNTANIDR TLENALQTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR ESLGLADLQP WDLGYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLNGLFAQIK KLYGIGFTEK TVPVWHKDVR YFELQQNGET


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFS DGTLQLPTAY LVCNFTPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGVPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS EDDEGRLKNW QQVLDSVRKE VAVVRPPEYN RFANSFGHIF


 


601
AGGYSAGYYS YAWAEVLSAD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR HSGFDNAA*






m128-1/a128-1 97.8% identity in 677 aa overlap





206

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3097>:










m206.seq




1
ATGTTTCCCC CCGACAAAAC CCTTTTCCTC TGTCTCAGCG CACTGCTCCT



 


51
CGCCTCATGC GGCACGACCT CCGGCAAACA CCGCCAACCG AAACCCAAAC


 


101
AGACAGTCCG GCAAATCCAA GCCGTCCGCA TCAGCCACAT CGACCGCACA


 


151
CAAGGCTCGC AGGAACTCAT GCTCCACAGC CTCGGACTCA TCGGCACGCC


 


201
CTACAAATGG GGCGGCAGCA GCACCGCAAC CGGCTTCGAT TGCAGCGGCA


 


251
TGATTCAATT CGTTTACAAr AACGCCCTCA ACGTCAAGCT GCCGCGCACC


 


301
GCCCGCGACA TGGCGGCGGC AAGCCGsAAA ATCCCCGAcA GCCGCyTCAA


 


351
GGCCGGCGAC CTCGTATTCT TCAACACCGG CGGCGCACAC CGCTACTCAC


 


401
ACGTCGGACT CTACATCGGC AACGGCGAAT TCATCCATGC CCCCAGCAGC


 


451
GGCAAAACCA TCAAAACCGA AAAACTCTCC ACACCGTTTT ACGCCAAAAA


 


501
CTACCTCGGC GCACATACTT TTTTTACAGA ATGA






This corresponds to the amino acid sequence <SEQ ID 3098; ORF 206>:










m206.pep..




1
MFPPDKTLFL CLSALLLASC GTTSGKHRQP KPKQTVRQIQ AVRISHIDRT



 


51
QGSQELMLHS LGLIGTPYKW GGSSTATGFD CSGMIQFVYK NALNVKLPRT


 


101
ARDMAAASRK IPDSRXKAGD LVFFNTGGAH RYSHVGLYIG NGEFIHAPSS


 


151
GKTIKTEKLS TPFYAKNYLG AHTFFTE*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3099>:










g206.seq




1
atgttttccc ccgacaaaac ccttttcctc tgtctcggcg cactgctcct



 


51
cgcctcatgc ggcacgacct ccggcaaaca ccgccaaccg aaacccaaac


 


101
agacagtccg gcaaatccaa gccgtccgca tcagccacat cggccgcaca


 


151
caaggctcgc aggaactcat gctccacagc ctcggactca tcggcacgcc


 


201
ctacaaatgg ggcggcagca gcaccgcaac cggcttcgac tgcagcggca


 


251
tgattcaatt ggtttacaaa aacgccctca acgtcaagct gccgcgcacc


 


301
gcccgcgaca tggcggcggc aagccgcaaa atccccgaca gccgcctcaa


 


351
ggccggcgac atcgtattct tcaacaccgg cggcgcacac cgctactcac


 


401
acgtcggact ctacatcggc aacggcgaat tcatccatgc ccccggcagc


 


451
ggcaaaacca tcaaaaccga aaaactctcc acaccgtttt acgccaaaaa


 


501
ctaccttgga gcgcatacgt tttttacaga atga






This corresponds to the amino acid sequence <SEQ ID 3100; ORF 206.ng>:










g206.pep




1
MFSPDKTLFL CLGALLLASC GTTSGKHRQP KPKQTVRQIQ AVRISHIGRT



 


51
QGSQELMLHS LGLIGTPYKW GGSSTATGFD CSGMIQLVYK NALNVKLPRT


 


101
ARDMAAASRK IPDSRLKAGD IVFFNTGGAH RYSHVGLYIG NGEFIHAPGS


 


151
GKTIKTEKLS TPFYAKNYLG AHTFFTE*






ORF 206 shows 96.0% identity over a 177 aa overlap with a predicted ORF (ORF 206.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3101>:










a206.seq




1
ATGTTTCCCC CCGACAAAAC CCTTTTCCTC TGTCTCAGCG CACTGCTCCT



 


51
CGCCTCATGC GGCACGACCT CCGGCAAACA CCGCCAACCG AAACCCAAAC


 


101
AGACAGTCCG GCAAATCCAA GCCGTCCGCA TCAGCCACAT CGACCGCACA


 


151
CAAGGCTCGC AGGAACTCAT GCTCCACAGC CTCGGACTCA TCGGCACGCC


 


201
CTACAAATGG GGCGGCAGCA GCACCGCAAC CGGCTTCGAT TGCAGCGGCA


 


251
TGATTCAATT CGTTTACAAA AACGCCCTCA ACGTCAAGCT GCCGCGCACC


 


301
GCCCGCGACA TGGCGGCGGC AAGCCGCAAA ATCCCCGACA GCCGCCTTAA


 


351
GGCCGGCGAC CTCGTATTCT TCAACACCGG CGGCGCACAC CGCTACTCAC


 


401
ACGTCGGACT CTATATCGGC AACGGCGAAT TCATCCATGC CCCCAGCAGC


 


451
GGCAAAACCA TCAAAACCGA AAAACTCTCC ACACCGTTTT ACGCCAAAAA


 


501
CTACCTCGGC GCACATACTT TCTTTACAGA ATGA






This corresponds to the amino acid sequence <SEQ ID 3102; ORF 206.a>:










a206.pep




1
MFPPDKTLFL CLSALLLASC GTTSGKHRQP KPKQTVRQIQ AVRISHIDRT



 


51
QGSQELMLHS LGLIGTPYKW GGSSTATGFD CSGMIQFVYK NALNVKLPRT


 


101
ARDMAAASRK IPDSRLKAGD LVFFNTGGAH RYSHVGLYIG NGEFIHAPSS


 


151
GKTIKTEKLS TPFYAKNYLG AHTFFTE*






m206/a206 99.4% identity in 177 aa overlap





287

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3103>:










m287.seq




1
ATGTTTAAAC GCAGCGTAAT CGCAATGGCT TGTATTTTTG CCCTTTCAGC



 


51
CTGCGGGGGC GGCGGTGGCG GATCGCCCGA TGTCAAGTCG GCGGACACGC


 


101
TGTCAAAACC TGCCGCCCCT GTTGTTTCTG AAAAAGAGAC AGAGGCAAAG


 


151
GAAGATGCGC CACAGGCAGG TTCTCAAGGA CAGGGCGCGC CATCCGCACA


 


201
AGGCAGTCAA GATATGGCGG CGGTTTCGGA AGAAAATACA GGCAATGGCG


 


251
GTGCGGTAAC AGCGGATAAT CCCAAAAATG AAGACGAGGT GGCACAAAAT


 


301
GATATGCCGC AAAATGCCGC CGGTACAGAT AGTTCGACAC CGAATCACAC


 


351
CCCGGATCCG AATATGCTTG CCGGAAATAT GGAAAATCAA GCAACGGATG


 


401
CCGGGGAATC GTCTCAGCCG GCAAACCAAC CGGATATGGC AAATGCGGCG


 


451
GACGGAATGC AGGGGGACGA TCCGTCGGCA GGCGGGCAAA ATGCCGGCAA


 


501
TACGGCTGCC CAAGGTGCAA ATCAAGCCGG AAACAATCAA GCCGCCGGTT


 


551
CTTCAGATCC CATCCCCGCG TCAAACCCTG CACCTGCGAA TGGCGGTAGC


 


601
AATTTTGGAA GGGTTGATTT GGCTAATGGC GTTTTGATTG ACGGGCCGTC


 


651
GCAAAATATA ACGTTGACCC ACTGTAAAGG CGATTCTTGT AGTGGCAATA


 


701
ATTTCTTGGA TGAAGAAGTA CAGCTAAAAT CAGAATTTGA AAAATTAAGT


 


751
GATGCAGACA AAATAAGTAA TTACAAGAAA GATGGGAAGA ATGATAAATT


 


801
TGTCGGTTTG GTTGCCGATA GTGTGCAGAT GAAGGGAATC AATCAATATA


 


851
TTATCTTTTA TAAACCTAAA CCCACTTCAT TTGCGCGATT TAGGCGTTCT


 


901
GCACGGTCGA GGCGGTCGCT TCCGGCCGAG ATGCCGCTGA TTCCCGTCAA


 


951
TCAGGCGGAT ACGCTGATTG TCGATGGGGA AGCGGTCAGC CTGACGGGGC


 


1001
ATTCCGGCAA TATCTTCGCG CCCGAAGGGA ATTACCGGTA TCTGACTTAC


 


1051
GGGGCGGAAA AATTGCCCGG CGGATCGTAT GCCCTTCGTG TTCAAGGCGA


 


1101
ACCGGCAAAA GGCGAAATGC TTGCGGGCGC GGCCGTGTAC AACGGCGAAG


 


1151
TACTGCATTT CCATACGGAA AACGGCCGTC CGTACCCGAC CAGGGGCAGG


 


1201
TTTGCCGCAA AAGTCGATTT CGGCAGCAAA TCTGTGGACG GCATTATCGA


 


1251
CAGCGGCGAT GATTTGCATA TGGGTACGCA AAAATTCAAA GCCGCCATCG


 


1301
ATGGAAACGG CTTTAAGGGG ACTTGGACGG AAAATGGCAG CGGGGATGTT


 


1351
TCCGGAAAGT TTTACGGCCC GGCCGGCGAG GAAGTGGCGG GAAAATACAG


 


1401
CTATCGCCCG ACAGATGCGG AAAAGGGCGG ATTCGGCGTG TTTGCCGGCA


 


1451
AAAAAGAGCA GGATTGA






This corresponds to the amino acid sequence <SEQ ID 3104; ORF 287>:










m287.pep




1
MFKRSVIAMA CIFALSACGG GGGGSPDVKS ADTLSKPAAP VVSEKETEAK



 


51
EDAPQAGSQG QGAPSAQGSQ DMAAVSEENT GNGGAVTADN PKNEDEVAQN


 


101
DMPQNAAGTD SSTPNHTPDP NMLAGNMENQ ATDAGESSQP ANQPDMANAA


 


151
DGMQGDDPSA GGQNAGNTAA QGANQAGNNQ AAGSSDPIPA SNPAPANGGS


 


201
NFGRVDLANG VLIDGPSQNI TLTHCKGDSC SGNNFLDEEV QLKSEFEKLS


 


251
DADKISNYKK DGKNDKFVGL VADSVQMKGI NQYIIFYKPK PTSFARFRRS


 


301
ARSRRSLPAE MPLIPVNQAD TLIVDGEAVS LTGHSGNIFA PEGNYRYLTY


 


351
GAEKLPGGSY ALRVQGEPAK GEMLAGAAVY NGEVLHFHTE NGRPYPTRGR


 


401
FAAKVDFGSK SVDGIIDSGD DLHMGTQKFK AAIDGNGFKG TWTENGSGDV


 


451
SGKFYGPAGE EVAGKYSYRP TDAEKGGFGV FAGKKEQD*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3105>:










g287.seq




1
atgtttaaac gcagtgtgat tgcaatggct tgtatttttc ccctttcagc



 


51
ctgtgggggc ggcggtggcg gatcgcccga tgtcaagtcg gcggacacgc


 


101
cgtcaaaacc ggccgccccc gttgttgctg aaaatgccgg ggaaggggtg


 


151
ctgccgaaag aaaagaaaga tgaggaggca gcgggcggtg cgccgcaagc


 


201
cgatacgcag gacgcaaccg ccggagaagg cagccaagat atggcggcag


 


251
tttcggcaga aaatacaggc aatggcggtg cggcaacaac ggacaacccc


 


301
aaaaatgaag acgcgggggc gcaaaatgat atgccgcaaa atgccgccga


 


351
atccgcaaat caaacaggga acaaccaacc cgccggttct tcagattccg


 


401
cccccgcgtc aaaccctgcc cctgcgaatg gcggtagcga ttttggaagg


 


451
acgaacgtgg gcaattctgt tgtgattgac ggaccgtcgc aaaatataac


 


501
gttgacccac tgtaaaggcg attcttgtaa tggtgataat ttattggatg


 


551
aagaagcacc gtcaaaatca gaatttgaaa aattaagtga tgaagaaaaa


 


601
attaagcgat ataaaaaaga cgagcaacgg gagaattttg tcggtttggt


 


651
tgctgacagg gtaaaaaagg atggaactaa caaatatatc atcttctata


 


701
cggacaaacc acctactcgt tctgcacggt cgaggaggtc gcttccggcc


 


751
gagattccgc tgattcccgt caatcaggcc gatacgctga ttgtggatgg


 


801
ggaagcggtc agcctgacgg ggcattccgg caatatcttc gcgcccgaag


 


851
ggaattaccg gtatctgact tacggggcgg aaaaattgcc cggcggatcg


 


901
tatgccctcc gtgtgcaagg cgaaccggca aaaggcgaaa tgcttgttgg


 


951
cacggccgtg tacaacggcg aagtgctgca tttccatatg gaaaacggcc


 


1001
gtccgtaccc gtccggaggc aggtttgccg caaaagtcga tttcggcagc


 


1051
aaatctgtgg acggcattat cgacagcggc gatgatttgc atatgggtac


 


1101
gcaaaaattc aaagccgcca tcgatggaaa cggctttaag gggacttgga


 


1151
cggaaaatgg cggcggggat gtttccggaa ggttttacgg cccggccggc


 


1201
gaggaagtgg cgggaaaata cagctatcgc ccgacagatg ctgaaaaggg


 


1251
cggattcggc gtgtttgccg gcaaaaaaga tcgggattga






This corresponds to the amino acid sequence <SEQ ID 3106; ORF 287.ng>:










g287.pep




1
MFKRSVIAMA CIFPLSACGG GGGGSPDVKS ADTPSKPAAP VVAENAGEGV



 


51
LPKEKKDEEA AGGAPQADTQ DATAGEGSQD MAAVSAENTG NGGAATTDNP


 


101
KNEDAGAQND MPQNAAESAN QTGNNQPAGS SDSAPASNPA PANGGSDFGR


 


151
TNVGNSVVID GPSQNITLTH CKGDSCNGDN LLDEEAPSKS EFEKLSDEEK


 


201
IKRYKKDEQR ENFVGLVADR VKKDGTNKYI IFYTDKPPTR SARSRRSLPA


 


251
EIPLIPVNQA DTLIVDGEAV SLTGHSGNIF APEGNYRYLT YGAEKLPGGS


 


301
YALRVQGEPA KGEMLVGTAV YNGEVLHFHM ENGRPYPSGG RFAAKVDFGS


 


351
KSVDGIIDSG DDLHMGTQKF KAAIDGNGFK GTWTENGGGD VSGRFYGPAG


 


401
EEVAGKYSYR PTDAEKGGFG VFAGKKDRD*






m287/g287 70.1% identity in 499 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3107>:










a287.seq




1
ATGTTTAAAC GCAGTGTGAT TGCAATGGCT TGTATTGTTG CCCTTTCAGC



 


51
CTGTGGGGGC GGCGGTGGCG GATCGCCCGA TGTTAAGTCG GCGGACACGC


 


101
TGTCAAAACC TGCCGCCCCT GTTGTTACTG AAGATGTCGG GGAAGAGGTG


 


151
CTGCCGAAAG AAAAGAAAGA TGAGGAGGCG GTGAGTGGTG CGCCGCAAGC


 


201
CGATACGCAG GACGCAACCG CCGGAAAAGG CGGTCAAGAT ATGGCGGCAG


 


251
TTTCGGCAGA AAATACAGGC AATGGCGGTG CGGCAACAAC GGATAATCCC


 


301
GAAAATAAAG ACGAGGGACC GCAAAATGAT ATGCCGCAAA ATGCCGCCGA


 


351
TACAGATAGT TCGACACCGA ATCACACCCC TGCACCGAAT ATGCCAACCA


 


401
GAGATATGGG AAACCAAGCA CCGGATGCCG GGGAATCGGC ACAACCGGCA


 


451
AACCAACCGG ATATGGCAAA TGCGGCGGAC GGAATGCAGG GGGACGATCC


 


501
GTCGGCAGGG GAAAATGCCG GCAATACGGC AGATCAAGCT GCAAATCAAG


 


551
CTGAAAACAA TCAAGTCGGC GGCTCTCAAA ATCCTGCCTC TTCAACCAAT


 


601
CCTAACGCCA CGAATGGCGG CAGCGATTTT GGAAGGATAA ATGTAGCTAA


 


651
TGGCATCAAG CTTGACAGCG GTTCGGAAAA TGTAACGTTG ACACATTGTA


 


701
AAGACAAAGT ATGCGATAGA GATTTCTTAG ATGAAGAAGC ACCACCAAAA


 


751
TCAGAATTTG AAAAATTAAG TGATGAAGAA AAAATTAATA AATATAAAAA


 


801
AGACGAGCAA CGAGAGAATT TTGTCGGTTT GGTTGCTGAC AGGGTAGAAA


 


851
AGAATGGAAC TAACAAATAT GTCATCATTT ATAAAGACAA GTCCGCTTCA


 


901
TCTTCATCTG CGCGATTCAG GCGTTCTGCA CGGTCGAGGC GGTCGCTTCC


 


951
GGCCGAGATG CCGCTGATTC CCGTCAATCA GGCGGATACG CTGATTGTCG


 


1001
ATGGGGAAGC GGTCAGCCTG ACGGGGCATT CCGGCAATAT CTTCGCGCCC


 


1051
GAAGGGAATT ACCGGTATCT GACTTACGGG GCGGAAAAAT TGTCCGGCGG


 


1101
ATCGTATGCC CTCAGTGTGC AAGGCGAACC GGCAAAAGGC GAAATGCTTG


 


1151
CGGGCACGGC CGTGTACAAC GGCGAAGTGC TGCATTTCCA TATGGAAAAC


 


1201
GGCCGTCCGT CCCCGTCCGG AGGCAGGTTT GCCGCAAAAG TCGATTTCGG


 


1251
CAGCAAATCT GTGGACGGCA TTATCGACAG CGGCGATGAT TTGCATATGG


 


1301
GTACGCAAAA ATTCAAAGCC GTTATCGATG GAAACGGCTT TAAGGGGACT


 


1351
TGGACGGAAA ATGGCGGCGG GGATGTTTCC GGAAGGTTTT ACGGCCCGGC


 


1401
CGGCGAAGAA GTGGCGGGAA AATACAGCTA TCGCCCGACA GATGCGGAAA


 


1451
AGGGCGGATT CGGCGTGTTT GCCGGCAAAA AAGAGCAGGA TTGA






This corresponds to the amino acid sequence <SEQ ID 3108; ORF 287.a>:










a287.pep




1
MFKRSVIAMA CIVALSACGG GGGGSPDVKS ADTLSKPAAP VVTEDVGEEV



 


51
LPKEKKDEEA VSGAPQADTQ DATAGKGGQD MAAVSAENTG NGGAATTDNP


 


101
ENKDEGPQND MPQNAADTDS STPNHTPAPN MPTRDMGNQA PDAGESAQPA


 


151
NQPDMANAAD GMQGDDPSAG ENAGNTADQA ANQAENNQVG GSQNPASSTN


 


201
PNATNGGSDF GRINVANGIK LDSGSENVTL THCKDKVCDR DFLDEEAPPK


 


251
SEFEKLSDEE KINKYKKDEQ RENFVGLVAD RVEKNGTNKY VIIYKDKSAS


 


301
SSSARFRRSA RSRRSLPAEM PLIPVNQADT LIVDGEAVSL TGHSGNIFAP


 


351
EGNYRYLTYG AEKLSGGSYA LSVQGEPAKG EMLAGTAVYN GEVLHFHMEN


 


401
GRPSPSGGRF AAKVDFGSKS VDGIIDSGDD LHMGTQKFKA VIDGNGFKGT


 


451
WTENGGGDVS GRFYGPAGEE VAGKYSYRPT DAEKGGFGVF AGKKEQD*






m287/a287 77.2% identity in 501 aa overlap




406

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3109>:










m406.seq




1
ATGCAAGCAC GGCTGCTGAT ACCTATTCTT TTTTCAGTTT TTATTTTATC



 


51
CGCCTGCGGG ACACTGACAG GTATTCCATC GCATGGCGGA GGTAAACGCT


 


101
TTGCGGTCGA ACAAGAACTT GTGGCCGCTT CTGCCAGAGC TGCCGTTAAA


 


151
GACATGGATT TACAGGCATT ACACGGACGA AAAGTTGCAT TGTACATTGC


 


201
CACTATGGGC GACCAAGGTT CAGGCAGTTT GACAGGGGGT CGCTACTCCA


 


251
TTGATGCACT GATTCGTGGC GAATACATAA ACAGCCCTGC CGTCCGTACC


 


301
GATTACACCT ATCCACGTTA CGAAACCACC GCTGAAACAA CATCAGGCGG


 


351
TTTGACAGGT TTAACCACTT CTTTATCTAC ACTTAATGCC CCTGCACTCT


 


401
CTCGCACCCA ATCAGACGGT AGCGGAAGTA AAAGCAGTCT GGGCTTAAAT


 


451
ATTGGCGGGA TGGGGGATTA TCGAAATGAA ACCTTGACGA CTAACCCGCG


 


501
CGACACTGCC TTTCTTTCCC ACTTGGTACA GACCGTATTT TTCCTGCGCG


 


551
GCATAGACGT TGTTTCTCCT GCCAATGCCG ATACAGATGT GTTTATTAAC


 


601
ATCGACGTAT TCGGAACGAT ACGCAACAGA ACCGAAATGC ACCTATACAA


 


651
TGCCGAAACA CTGAAAGCCC AAACAAAACT GGAATATTTC GCAGTAGACA


 


701
GAACCAATAA AAAATTGCTC ATCAAACCAA AAACCAATGC GTTTGAAGCT


 


751
GCCTATAAAG AAAATTACGC ATTGTGGATG GGGCCGTATA AAGTAAGCAA


 


801
AGGAATTAAA CCGACGGAAG GATTAATGGT CGATTTCTCC GATATCCGAC


 


851
CATACGGCAA TCATACGGGT AACTCCGCCC CATCCGTAGA GGCTGATAAC


 


901
AGTCATGAGG GGTATGGATA CAGCGATGAA GTAGTGCGAC AACATAGACA


 


951
AGGACAACCT TGA






This corresponds to the amino acid sequence <SEQ ID 3110; ORF 406>:










m406.pep




1
MQARLLIPIL FSVFILSACG TLTGIPSHGG GKRFAVEQEL VAASARAAVK



 


51
DMDLQALHGR KVALYIATMG DQGSGSLTGG RYSIDALIRG EYINSPAVRT


 


101
DYTYPRYETT AETTSGGLTG LTTSLSTLNA PALSRTQSDG SGSKSSLGLN


 


151
IGGMGDYRNE TLTTNPRDTA FLSHLVQTVF FLRGIDVVSP ANADTDVFIN


 


201
IDVFGTIRNR TEMHLYNAET LKAQTKLEYF AVDRTNKKLL IKPKTNAFEA


 


251
AYKENYALWM GPYKVSKGIK PTEGLMVDFS DIRPYGNHTG NSAPSVEADN


 


301
SHEGYGYSDE VVRQHRQGQP *






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3111>:










g406.seq




1
ATGCGGGCAC GGCTGCTGAT ACCTATTCTT TTTTCAGTTT TTATTTTATC



 


51
CGCCTGCGGG ACACTGACAG GTATTCCATC GCATGGCGGA GGCAAACGCT


 


101
TCGCGGTCGA ACAAGAACTT GTGGCCGCTT CTGCCAGAGC TGCCGTTAAA


 


151
GACATGGATT TACAGGCATT ACACGGACGA AAAGTTGCAT TGTACATTGC


 


201
AACTATGGGC GACCAAGGTT CAGGCAGTTT GACAGGGGGT CGCTACTCCA


 


251
TTGATGCACT GATTCGCGGC GAATACATAA ACAGCCCTGC CGTCCGCACC


 


301
GATTACACCT ATCCGCGTTA CGAAACCACC GCTGAAACAA CATCAGGCGG


 


351
TTTGACGGGT TTAACCACTT CTTTATCTAC ACTTAATGCC CCTGCACTCT


 


401
CGCGCACCCA ATCAGACGGT AGCGGAAGTA GGAGCAGTCT GGGCTTAAAT


 


451
ATTGGCGGGA TGGGGGATTA TCGAAATGAA ACCTTGACGA CCAACCCGCG


 


501
CGACACTGCC TTTCTTTCCC ACTTGGTGCA GACCGTATTT TTCCTGCGCG


 


551
GCATAGACGT TGTTTCTCCT GCCAATGCCG ATACAGATGT GTTTATTAAC


 


601
ATCGACGTAT TCGGAACGAT ACGCAACAGA ACCGAAATGC ACCTATACAA


 


651
TGCCGAAACA CTGAAAGCCC AAACAAAACT GGAATATTTC GCAGTAGACA


 


701
GAACCAATAA AAAATTGCTC ATCAAACCCA AAACCAATGC GTTTGAAGCT


 


751
GCCTATAAAG AAAATTACGC ATTGTGGATG GGGCCGTATA AAGTAAGCAA


 


801
AGGAATCAAA CCGACGGAAG GATTGATGGT CGATTTCTCC GATATCCAAC


 


851
CATACGGCAA TCATACGGGT AACTCCGCCC CATCCGTAGA GGCTGATAAC


 


901
AGTCATGAGG GGTATGGATA CAGCGATGAA GCAGTGCGAC AACATAGACA


 


951
AGGGCAACCT TGA






This corresponds to the amino acid sequence <SEQ ID 3112; ORF 406>:










g406.pep




1
MRARLLIPIL FSVFILSACG TLTGIPSHGG GKRFAVEQEL VAASARAAVK



 


51
DMDLQALHGR KVALYIATMG DQGSGSLTGG RYSIDALIRG EYINSPAVRT


 


101
DYTYPRYETT AETTSGGLTG LTTSLSTLNA PALSRTQSDG SGSRSSLGLN


 


151
IGGMGDYRNE TLTTNPRDTA FLSHLVQTVF FLRGIDVVSP ANADTDVFIN


 


201
IDVFGTIRNR TEMHLYNAET LKAQTKLEYF AVDRTNKKLL IKPKTNAFEA


 


251
AYKENYALWM GPYKVSKGIK PTEGLMVDFS DIQPYGNHTG NSAPSVEADN


 


301
SHEGYGYSDE AVRQHRQGQP *






ORF 406 shows 98.8% identity over a 320 aa overlap with a predicted ORF (ORF406.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3113>:










a406.seq




1
ATGCAAGCAC GGCTGCTGAT ACCTATTCTT TTTTCAGTTT TTATTTTATC



 


51
CGCCTGCGGG ACACTGACAG GTATTCCATC GCATGGCGGA GGTAAACGCT


 


101
TCGCGGTCGA ACAAGAACTT GTGGCCGCTT CTGCCAGAGC TGCCGTTAAA


 


151
GACATGGATT TACAGGCATT ACACGGACGA AAAGTTGCAT TGTACATTGC


 


201
AACTATGGGC GACCAAGGTT CAGGCAGTTT GACAGGGGGT CGCTACTCCA


 


251
TTGATGCACT GATTCGTGGC GAATACATAA ACAGCCCTGC CGTCCGTACC


 


301
GATTACACCT ATCCACGTTA CGAAACCACC GCTGAAACAA CATCAGGCGG


 


351
TTTGACAGGT TTAACCACTT CTTTATCTAC ACTTAATGCC CCTGCACTCT


 


401
CGCGCACCCA ATCAGACGGT AGCGGAAGTA AAAGCAGTCT GGGCTTAAAT


 


451
ATTGGCGGGA TGGGGGATTA TCGAAATGAA ACCTTGACGA CTAACCCGCG


 


501
CGACACTGCC TTTCTTTCCC ACTTGGTACA GACCGTATTT TTCCTGCGCG


 


551
GCATAGACGT TGTTTCTCCT GCCAATGCCG ATACGGATGT GTTTATTAAC


 


601
ATCGACGTAT TCGGAACGAT ACGCAACAGA ACCGAAATGC ACCTATACAA


 


651
TGCCGAAACA CTGAAAGCCC AAACAAAACT GGAATATTTC GCAGTAGACA


 


701
GAACCAATAA AAAATTGCTC ATCAAACCAA AAACCAATGC GTTTGAAGCT


 


751
GCCTATAAAG AAAATTACGC ATTGTGGATG GGACCGTATA AAGTAAGCAA


 


801
AGGAATTAAA CCGACAGAAG GATTAATGGT CGATTTCTCC GATATCCAAC


 


851
CATACGGCAA TCATATGGGT AACTCTGCCC CATCCGTAGA GGCTGATAAC


 


901
AGTCATGAGG GGTATGGATA CAGCGATGAA GCAGTGCGAC GACATAGACA


 


951
AGGGCAACCT TGA






This corresponds to the amino acid sequence <SEQ ID 3114; ORF 406.a>:










a406.pep




1
MQARLLIPIL FSVFILSACG TLTGIPSHGG GKRFAVEQEL VAASARAAVK



 


51
DMDLQALHGR KVALYIATMG DQGSGSLTGG RYSIDALIRG EYINSPAVRT


 


101
DYTYPRYETT AETTSGGLTG LTTSLSTLNA PALSRTQSDG SGSKSSLGLN


 


151
IGGMGDYRNE TLTTNPRDTA FLSHLVQTVF FLRGIDVVSP ANADTDVFIN


 


201
IDVFGTIRNR TEMHLYNAET LKAQTKLEYF AVDRTNKKLL IKPKTNAFEA


 


251
AYKENYALWM GPYKVSKGIK PTEGLMVDFS DIQPYGNHMG NSAPSVEADN


 


301
SHEGYGYSDE AVRRHRQGQP *






m406/a406 98.8% identity in 320 aa overlap




Example 2
Expression of ORF 919
The primer described in Table 1 for ORF 919 was used to locate and clone ORF 919. The predicted gene 919 was cloned in pET vector and expressed in E. coli. The product of protein expression and purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 919-His fusion protein purification. Mice were immunized with the purified 919-His and sera were used for Western blot (panel B), FACS analysis (panel C), bactericidal assay (panel D), and ELISA assay (panel E). Symbols: M1, molecular weight marker; PP, purified protein, TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vesicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 919 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 919 are provided in FIG. 10. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 919 and the amino acid sequence encoded thereby is provided in Example 1.
Example 3
Expression of ORF 279
The primer described in Table 1 for ORF 279 was used to locate and clone ORF 279. The predicted gene 279 was cloned in pGex vector and expressed in E. coli. The product of protein expression and purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 279-GST purification. Mice were immunized with the purified 279-GST and sera were used for Western blot analysis (panel B), FACS analysis (panel C), bactericidal assay (panel D), and ELISA assay (panel E). Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vescicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 279 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 279 are provided in FIG. 11. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 279 and the amino acid sequence encoded thereby is provided in Example 1.
Example 4
Expression of ORF 576 and 576-1
The primer described in Table 1 for ORF 576 was used to locate and clone ORF 576. The predicted gene 576 was cloned in pGex vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 576-GST fusion protein purification. Mice were immunized with the purified 576-GST and sera were used for Western blot (panel B), FACS analysis (panel C), bactericidal assay (panel D), and ELISA assay (panel E). Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vescicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that ORF 576 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 576 are provided in FIG. 12. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 576 and the amino acid sequence encoded thereby is provided in Example 1.
Example 5
Expression of ORF 519 and 519-1
The primer described in Table 1 for ORF 519 was used to locate and clone ORF 519. The predicted gene 519 was cloned in pET vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 519-His fusion protein purification. Mice were immunized with the purified 519-His and sera were used for Western blot (panel B), FACS analysis (panel C), bactericidal assay (panel D), and ELISA assay (panel E). Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vesicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 519 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 519 are provided in FIG. 13. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand Immunol Suppl 11:9). The nucleic acid sequence of ORF 519 and the amino acid sequence encoded thereby is provided in Example 1.
Example 6
Expression of ORF 121 and 121-1
The primer described in Table 1 for ORF 121 was used to locate and clone ORF 121. The predicted gene 121 was cloned in pET vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 121-His fusion protein purification. Mice were immunized with the purified 121-His and sera were used for Western blot analysis (panel B), FACS analysis (panel C), bactericidal assay (panel D), and ELISA assay (panel E). Results show that 121 is a surface-exposed protein. Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vescicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 121 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 121 are provided in FIG. 14. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 121 and the amino acid sequence encoded thereby is provided in Example 1.
Example 7
Expression of ORF 128 and 128-1
The primer described in Table 1 for ORF 128 was used to locate and clone ORF 128. The predicted gene 128 was cloned in pET vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 128-His purification. Mice were immunized with the purified 128-His and sera were used for Western blot analysis (panel B), FACS analysis (panel C), bactericidal assay (panel D) and ELISA assay (panel E). Results show that 128 is a surface-exposed protein. Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vesicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 128 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 128 are provided in FIG. 15. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 128 and the amino acid sequence encoded thereby is provided in Example 1.
Example 8
Expression of ORF 206
The primer described in Table 1 for ORF 206 was used to locate and clone ORF 206. The predicted gene 206 was cloned in pET vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 206-His purification. Mice were immunized with the purified 206-His and sera were used for Western blot analysis (panel B). It is worthnoting that the immunoreactive band in protein extracts from meningococcus is 38 kDa instead of 17 kDa (panel A). To gain information on the nature of this antibody staining we expressed ORF 206 in E. coli without the His-tag and including the predicted leader peptide. Western blot analysis on total protein extracts from E. coli expressing this native form of the 206 protein showed a recative band at a position of 38 kDa, as observed in meningococcus. We conclude that the 38 kDa band in panel B) is specific and that anti-206 antibodies, likely recognize a multimeric protein complex. In panel C is shown the FACS analysis, in panel D the bactericidal assay, and in panel E) the ELISA assay. Results show that 206 is a surface-exposed protein. Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vesicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 206 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 519 are provided in FIG. 16. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 206 and the amino acid sequence encoded thereby is provided in Example 1.
Example 9
Expression of ORF 287
The primer described in Table 1 for ORF 287 was used to locate and clone ORF 287. The predicted gene 287 was cloned in pGex vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 287-GST fusion protein purification. Mice were immunized with the purified 287-GST and sera were used for FACS analysis (panel B), bactericidal assay (panel C), and ELISA assay (panel D). Results show that 287 is a surface-exposed protein. Symbols: M1, molecular weight marker. Arrow indicates the position of the main recombinant protein product (A). These experiments confirm that 287 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 287 are provided in FIG. 17. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 287 and the amino acid sequence encoded thereby is provided in Example 1.
Example 10
Expression of ORF 406
The primer described in Table 1 for ORF 406 was used to locate and clone ORF 406. The predicted gene 406 was cloned in pET vector and expressed in E. coli. The product of protein purification was analyzed by SDS-PAGE. In panel A) is shown the analysis of 406-His fusion protein purification. Mice were immunized with the purified 406-His and sera were used for Western blot analysis (panel B), FACS analysis (panel C), bactericidal assay (panel D), and ELISA assay (panel E). Results show that 406 is a surface-exposed protein. Symbols: M1, molecular weight marker; TP, N. meningitidis total protein extract; OMV, N. meningitidis outer membrane vescicle preparation. Arrows indicate the position of the main recombinant protein product (A) and the N. meningitidis immunoreactive band (B). These experiments confirm that 406 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 406 are provided in FIG. 18. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 406 and the amino acid sequence encoded thereby is provided in Example 1.
Example 11
Table 2 lists several Neisseria strains which were used to assess the conservation of the sequence of ORF 225 among different strains.







TABLE 2







225 gene variability: List of used Neisseria strains











Identification





number
Strains
Source/reference











Group B











zo01_225
NG6/88
R. Moxon/Seiler et al., 1996



zo02_225
BZ198
R. Moxon/Seiler et al., 1996



zo03_225
NG3/88
R. Moxon/Seiler et al., 1996



zo04_225
297-0
R. Moxon/Seiler et al., 1996



zo05_225
1000
R. Moxon/Seiler et al., 1996



zo06_225
BZ147
R. Moxon/Seiler et al., 1996



zo07_225
BZ169
R. Moxon/Seiler et al., 1996



zo08_225
528
R. Moxon/Seiler et al., 1996



zo09_225
NGP165
R. Moxon/Seiler et al., 1996



zo10_225
BZ133
R. Moxon/Seiler et al., 1996



zo11_225
NGE31
R. Moxon/Seiler et al., 1996



zo12_225
NGF26
R. Moxon/Seiler et al., 1996



zo13_225
NGE28
R. Moxon/Seiler et al., 1996



zo14_225
NGH38
R. Moxon/Seiler et al., 1996



zo15_225
SWZ107
R. Moxon/Seiler et al., 1996



zo16_225
NGH15
R. Moxon/Seiler et al., 1996



zo17_225
NGH36
R. Moxon/Seiler et al., 1996



zo18_225
BZ232
R. Moxon/Seiler et al., 1996



zo19_225
BZ83
R. Moxon/Seiler et al., 1996



zo20_225
44/76
R. Moxon/Seiler et al., 1996



zo21_225
MC58
R. Moxon



zo96_225
2996
Our collection







Group A











zo22_225
205900
R. Moxon



zo23_225
F6124
R. Moxon



z2491
Z2491
R. Moxon/Maiden et al., 1998







Group C











zo24_225
90/18311
R. Moxon



zo25_225
93/4286
R. Moxon







Others











zo26_225
A22 (group W)
R. Moxon/Maiden et al., 1998



zo27_225
E26 (group X)
R. Moxon/Maiden et al., 1998



zo28_225
860800 (group Y)
R. Moxon/Maiden et al., 1998



zo29_225
E32 (group Z)
R. Moxon/Maiden et al., 1998







Gonococcus











zo32_225
Ng F62
R. Moxon/Maiden et al., 1998



zo33_225
Ng SN4
R. Moxon



fa1090
FA1090
R. Moxon







References:



Seiler A. et al., Mol. Microbiol., 1996, 19(4): 841-856.



Maiden et al., Proc. Natl. Acad. Sci. USA, 1998, 95: 3140-3145.






The amino acid sequences for each listed strain are as follows:








>FA1090 <SEQ ID 3115>



MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPVNRAPARRAG


NADELIGSAMGLNEQPVLPVNRAPARRAGNADELIGSAMGLLGIAYRYGGTSVSTGFDCS


GFMQHIFKRAMGINLPRTSAEQARMGAPVARSELQPGDMVFFRTLGGSRISHVGLYIGNN


RFIHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN*


 


Z2491 <SEQ ID 3116>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRVPARRAGNA


DELIGNAMGLNEQPVLPVNRAPARRAGNADELIGNAMGLLGIAYRYGGTSISTGFDCSGF


MQHIFKRAMGINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNNRF


IHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN*


 


ZO01_225 <SEQ ID 3117>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO02_225 <SEQ ID 3118>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO03_225 <SEQ ID 3119>


MDSFFKPAVWAVLWLMFAVRLALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO04_225 <SEQ ID 3120>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO05_225 <SEQ ID 3121>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGSAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO06_225 <SEQ ID 3122>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO07_225 <SEQ ID 3123>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO08_225 <SEQ ID 3124>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGSAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO09_225 <SEQ ID 3125>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO10_225 <SEQ ID 3126>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO11_225 <SEQ ID 3127>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLNEQPVLPVNRAPARRAGNADELIGNAMGLLGIAYRYGGTSVSTGFDCSGF


MQHIFKRAMGINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNNRF


IHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN*


 


ZO12_225 <SEQ ID 3128>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO13_225 <SEQ ID 3129>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPVNRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFIQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO14_225 <SEQ ID 3130>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO15_225 <SEQ ID 3131>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLLGIAYRYGGTSVSTGFDCS


GFMQHIFKRAMGINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNN


RFIHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN*


 


ZO16_225 <SEQ ID 3132>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO17_225 <SEQ ID 3133>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO18_225 <SEQ ID 3134>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO19_225 <SEQ ID 3135>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO20_225 <SEQ ID 3136>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPINRAPARRAGNADELIGSAMGLNEQPVLPVNRVPARRAGNA


DELIGNAMGLNEQPVLPVNRAPARRAGNADELIGNAMGLLGIAYRYGGTSVSTGFDCSGF


MQHIFKRAMGINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNNRF


IHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN*


 


ZO21_225 <SEQ ID 3137>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO22_225 <SEQ ID 3138>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO23_225 <SEQ ID 3139>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO24_225 <SEQ ID 3140>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO25_225 <SEQ ID 3141>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO26_225 <SEQ ID 3142>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO27_225 <SEQ ID 3143>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO28_225 <SEQ ID 3144>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO29_225 <SEQ ID 3145>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*


 


ZO32_225 <SEQ ID 3146>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPVNRAPARRAG


NADELIGSAMGLNEQPVLPVNRAPARRAGNADELIGSAMGLLGIAYRYGGTSVSTGFDCS


GFMQHIFKRAMGINLPRTSAEQARMGAPVARSELQPGDMVFFRTLGGSRISHVGLYIGNN


RFIHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN*


 


ZO33_225 <SEQ ID 3147>


MDSFFKPAVWAVLWLMFAVRSALADELTNLLSSREQILRQFAEDEQPVLPVNRAPARRAG


NADELIGSAMGLNEQPVLPVNRAPARRAGNADELIGSAMGLLGIAYRYGGTSVSTGFDCS


GFMQHIFKRAMGINLPRTSAEQARMGAPVARSELQPGDMVFFRTLGGSRISHVGLYIGNN


RFIHAPRTGKNIEITSLSHKYWSGKYAFARRIKKNDPSRFLN*


 


ZO96_225 <SEQ ID 3148>


MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAG


NADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNA


DELIGNAMGLLGIAYRYGGTSISTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVAR


SELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTGKNIEITSLSHKYWSGKYAFARR


VKKNDPSRFLN*






FIG. 19 shows the results of aligning the sequences of each of these strains. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. As is readily discernible, there is significant conservation among the various strains of ORF 225, further confirming its utility as an antigen for both vaccines and diagnostics.
Example 12
Table 3 lists several Neisseria strains which were used to assess the conservation of the sequence of ORF 235 among different strains.







TABLE 3







235 gene variability: List of used Neisseria strains











Identification





number
Strains
Reference











Group B











gnmzq01
NG6/88
Seiler et al., 1996



gnmzq02
BZ198
Seiler et al., 1996



gnmzq03
NG3/88
Seiler et al., 1996



gnmzq04
1000
Seiler et al., 1996



gnmzq05
1000
Seiler et al., 1996



gnmzq07
BZ169
Seiler et al., 1996



gnmzq08
528
Seiler et al., 1996



gnmzq09
NGP165
Seiler et al., 1996



gnmzq10
BZ133
Seiler et al., 1996



gnmzq11
NGE31
Seiler et al., 1996



gnmzq13
NGE28
Seiler et al., 1996



gnmzq14
NGH38
Seiler et al., 1996



gnmzq15
SWZ107
Seiler et al., 1996



gnmzq16
NGH15
Seiler et al., 1996



gnmzq17
NGH36
Seiler et al., 1996



gnmzq18
BZ232
Seiler et al., 1996



gnmzq19
BZ83
Seiler et al., 1996



gnmzq21
MC58
Virji et al., 1992







Group A











gnmzq22
205900
Our collection



gnmzq23
F6124
Our collection



z2491
Z2491
Maiden et al., 1998







Group C











gnmzq24
90/18311
Our collection



gnmzq25
93/4286
Our collection







Others











gnmzq26
A22 (group W)
Maiden et al., 1998



gnmzq27
E26 (group X)
Maiden et al., 1998



gnmzq28
860800 (group Y)
Maiden et al., 1998



gnmzq29
E32 (group Z)
Maiden et al., 1998



gnmzq31
N. lactamica
Our collection







Gonococcus











gnmzq32
Ng F62
Maiden et al., 1998



gnmzq33
Ng SN4
Our collection



fa1090
FA1090
Dempsey et al. 1991







References:



Seiler A. et al., Mol. Microbiol., 1996, 19(4): 841-856.



Maiden R. et al., Proc. Natl. Acad. Sci. USA, 1998, 95: 3140-3145.



Virji M. et al., Mol. Microbiol., 1992, 6: 1271-1279



Dempsey J. F. et al., J. Bacteriol., 1991, 173: 5476-5486






The amino acid sequences for each listed strain are as follows:








FA1090 <SEQ ID 3149>



MKPLILGLAAVLALSACQVRKAPDLDYTSFKESKPASILVVPPLNESPDVNGTWGMLAST


AAPISEAGYYVFPAAVVEETFKENGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSRNGILKGPRFVEEQPK*


 


GNMZQ01 <SEQ ID 3150>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKENGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANNLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ02 <SEQ ID 3151>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ03 <SEQ ID 3152>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ04 <SEQ ID 3153>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ05 <SEQ ID 3154>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKENGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANNLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ07 <SEQ ID 3155>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ08 <SEQ ID 3156>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKENGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANNLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ09 <SEQ ID 3157>


MKPLILGLAAALVLSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGMLAST


AEPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVQPEKLHQIFGNDAVLYITITEYGTS


YQILDSVTTVSARARLVDSRNGKVLWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ10 <SEQ ID 3158>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ11 <SEQ ID 3159>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ13 <SEQ ID 3160>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ14 <SEQ ID 3161>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ15 <SEQ ID 3162>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ16 <SEQ ID 3163>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ17 <SEQ ID 3164>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ18 <SEQ ID 3165>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ19 <SEQ ID 3166>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ21 <SEQ ID 3166>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ22 <SEQ ID 3167>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ23 <SEQ ID 3168>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ24 <SEQ ID 3169>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ25 <SEQ ID 3170>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ26 <SEQ ID 3171>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGMLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ27 <SEQ ID 3172>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ28 <SEQ ID 3173>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ29 <SEQ ID 3174>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ31 <SEQ ID 3175>


MKPLILGLAAVLALSACQVQKAPDFDYTAFKESKPASILVVPPLNESPDVNGTWGMLAST


AEPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITITEYGTS


YQILDSVTTVSARARLVDSRNGKVLWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKAAAYDLLSPYSHNGILKGPRFVEEQPK*


 


GNMZQ32 <SEQ ID 3176>


MKPLILGLAAVLALSACQVRKAPDLDYTSFKESKPASILVVPPLNESPDVNGTWGMLAST


AAPISEAGYYVFPAAVVEETFKENGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSRNGILKGPRFVEEQPK*


 


GNMZQ33 <SEQ ID 3177>


MKPLILGLAAVLALSACQVRKAPDLDYTSFKESKPASILVVPPLNESPDVNGTWGMLAST


AAPISEAGYYVFPAAVVEETFKENGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVGAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSRNGILKGPRFVEEQPK*


 


Z2491 <SEQ ID 3178>


MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLAST


AAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTS


YQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLT


DRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK*






FIG. 20 shows the results of aligning the sequences of each of these strains. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. As is readily discernible, there is significant conservation among the various strains of ORF 235, further confirming its utility as an antigen for both vaccines and diagnostics.
Example 13
Table 4 lists several Neisseria strains which were used to assess the conservation of the sequence of ORF 287 among different strains.







TABLE 4







287 gene variability: List of used Neisseria strains











Identification





number
Strains
Reference











Group B











287_2
BZ198
Seiler et al., 1996



287_9
NGP165
Seiler et al., 1996



287_14
NGH38
Seiler et al., 1996



287_21
MC58
Virji et al., 1992







Group A











z2491
Z2491
Maiden et al., 1998







Gonococcus











fa1090
FA1090
Dempsey et al. 1991







References:



Seiler A. et al., Mol. Microbiol., 1996, 19(4): 841-856.



Maiden R. et al., Proc. Natl. Acad. Sci. USA, 1998, 95: 3140-3145.



Virji M. et al., Mol. Microbiol., 1992, 6: 1271-1279



Dempsey J. F. et al., J. Bacteriol., 1991, 173: 5476-5486






The amino acid sequences for each listed strain are as follows:








287_14 <SEQ ID 3179>



MFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQG


QGAPSAQGGQDMAAVSEENTGNGGAAATDKPKNEDEGAQNDMPQNAADTDSLTPNHTPAS


NMPAGNMENQAPDAGESEQPANQPDMANTADGMQGDDPSAGGENAGNTAAQGTNQAENNQ


TAGSQNPASSTNPSATNSGGDFGRTNVGNSVVIDGPSQNITLTHCKGDSCSGNNFLDEEV


QLKSEFEKLSDADKISNYKKDGKNDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFAR


FRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLP


GGSYALRVQGEPSKGEMLAGTAVYNGEVLHFHTENGRPSPSRGRFAAKVDFGSKSVDGII


DSGDGLHMGTQKFKAAIDGNGFKGTWTENGGGDVSGKFYGPAGEEVAGKYSYRPTDAEKG


GFGVFAGKKEQD*


 


287_2 <SEQ ID 3180>


MFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQG


QGAPSAQGGQDMAAVSEENTGNGGAAATDKPKNEDEGAQNDMPQNAADTDSLTPNHTPAS


NMPAGNMENQAPDAGESEQPANQPDMANTADGMQGDDPSAGGENAGNTAAQGTNQAENNQ


TAGSQNPASSTNPSATNSGGDFGRTNVGNSVVIDGPSQNITLTHCKGDSCSGNNFLDEEV


QLKSEFEKLSDADKISNYKKDGKNDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFAR


FRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLP


GGSYALRVQGEPSKGEMLAGTAVYNGEVLHFHTENGRPSPSRGRFAAKVDFGSKSVDGII


DSGDGLHMGTQKFKAAIDGNGFKGTWTENGGGDVSGKFYGPAGEEVAGKYSYRPTDAEKG


GFGVFAGKKEQD*


 


287_21. <SEQ ID 3181>


MFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQG


QGAPSAQGSQDMAAVSEENTGNGGAVTADNPKNEDEVAQNDMPQNAAGTDSSTPNHTPDP


NMLAGNMENQATDAGESSQPANQPDMANAADGMQGDDPSAGGQNAGNTAAQGANQAGNNQ


AAGSSDPIPASNPAPANGGSNFGRVDLANGVLIDGPSQNITLTHCKGDSCSGNNFLDEEV


QLKSEFEKLSDADKISNYKKDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFARFRRS


ARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLPGGSY


ALRVQGEPAKGEMLAGAAVYNGEVLHFHTENGRPYPTRGRFAAKVDFGSKSVDGIIDSGD


DLHMGTQKFKAAIDGNGFKGTWTENGSGDVSGKFYGPAGEEVAGKYSYRPTDAEKGGFGV


FAGKKEQD*


 


287_9 <SEQ ID 3182>


MFKRSVIAMACIVALSACGGGGGGSPDVKSADTLSKPAAPVVTEDVGEEVLPKEKKDEEA


VSGAPQADTQDATAGKGGQDMAAVSAENTGNGGAATTDNPENKDEGPQNDMPQNAADTDS


STPNHTPAPNMPTRDMGNQAPDAGESAQPANQPDMANAADGMQGDDPSAGENAGNTADQA


ANQAENNQVGGSQNPASSTNPNATNGGSDFGRINVANGIKLDSGSENVTLTHCKDKVCDR


DFLDEEAPPKSEFEKLSDEEKINKYKKDEQRENFVGLVADRVEKNGTNKYVIIYKDKSAS


SSSARFRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYG


AEKLSGGSYALSVQGEPAKGEMLAGTAVYNGEVLHFHMENGRPSPSGGRFAAKVDFGSKS


VDGIIDSGDDLHMGTQKFKAVIDGNGFKGTWTENGGGDVSGRFYGPAGEEVAGKYSYRPT


DAEKGGFGVFAGKKEQD*


 


FA1090 <SEQ ID 3183>


MFKRSVIAMACIFPLSACGGGGGGSPDVKSADTPSKPAAPVVAENAGEGVLPKEKKDEEA


AGGAPQADTQDATAGEGSQDMAAVSAENTGNGGAATTDNPKNEDAGAQNDMPQNAAESAN


QTGNNQPAGSSDSAPASNPAPANGGSDFGRTNVGNSVVIDGPSQNITLTHCKGDSCNGDN


LLDEEAPSKSEFEKLSDEEKIKRYKKDEQRENFVGLVADRVKKDGTNKYIIFYTDKPPTR


SARSRRSLPAEIPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLPGGS


YALRVQGEPAKGEMLVGTAVYNGEVLHFHMENGRPYPSGGRFAAKVDFGSKSVDGIIDSG


DDLHMGTQKFKAAIDGNGFKGTWTENGGGDVSGRFYGPAGEEVAGKYSYRPTDAEKGGFG


VFAGKKDRD*


 


Z2491 <SEQ ID 3184>


MFKRSVIAMACIFALSACGGGGGGSPDVKSADTLSKPAAPVVSEKETEAKEDAPQAGSQG


QGAPSAQGSQDMAAVSEENTGNGGAVTADNPKNEDEVAQNDMPQNAAGTDSSTPNHTPDP


NMLAGNMENQATDAGESSQPANQPDMANAADGMQGDDPSAGGQNAGNTAAQGANQAGNNQ


AAGSSDPIPASNPAPANGGSNFGRVDLANGVLIDGPSQNITLTHCKGDSCSGNNFLDEEV


QLKSEFEKLSDADKISNYKKDGKNDKFVGLVADSVQMKGINQYIIFYKPKPTSFARFRRS


ARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNIFAPEGNYRYLTYGAEKLPGGSY


ALRVQGEPAKGEMLAGAAVYNGEVLHFHTENGRPYPTRGRFAAKVDFGSKSVDGIIDSGD


DLHMGTQKFKAAIDGNGFKGTWTENGSGDVSGKFYGPAGEEVAGKYSYRPTDAEKGGFGV


FAGKKEQD*






FIG. 21 shows the results of aligning the sequences of each of these strains. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. As is readily discernible, there is significant conservation among the various strains of ORF 225, further confirming its utility as an antigen for both vaccines and diagnostics.
Example 14
Table 5 lists several Neisseria strains which were used to assess the conservation of the sequence of ORF 519 among different strains.







TABLE 5







519 gene variability: List of used Neisseria strains









Identification




number
Strains
Source/reference










Group B









zv01_519
NG6/88
R. Moxon/Seiler et al., 1996


zv02_519
BZ198
R. Moxon/Seiler et al., 1996


zv03_519ass
NG3/88
R. Moxon/Seiler et al., 1996


zv04_519
297-0
R. Moxon/Seiler et al., 1996


zv05_519
1000
R. Moxon/Seiler et al., 1996


zv06_519ass
BZ147
R. Moxon/Seiler et al., 1996


zv07_519
BZ169
R. Moxon/Seiler et al., 1996


zv11_519
NGE31
R. Moxon/Seiler et al., 1996


zv12_519
NGF26
R. Moxon/Seiler et al., 1996


zv18_519
BZ232
R. Moxon/Seiler et al., 1996


zv19_519
BZ83
R. Moxon/Seiler et al., 1996


zv20_519ass
44/76
R. Moxon/Seiler et al., 1996


zv21_519ass
MC58
R. Moxon


zv96_519
2996
Our collection







Group A









zv22_519ass
205900
R. Moxon


z2491_519
Z2491
R. Moxon/Maiden et al., 1998







Others









zv26_519
A22 (group W)
R. Moxon/Maiden et al., 1998


zv27_519
E26 (group X)
R. Moxon/Maiden et al., 1998


zv28_519
860800 (group Y)
R. Moxon/Maiden et al., 1998


zv29_519ass
E32 (group Z)
R. Moxon/Maiden et al., 1998







Gonococcus









zv32_519
Ng F62
R. Moxon/Maiden et al., 1998


fa1090_519
FA1090
R. Moxon





References:


Seiler A. et al., Mol. Microbiol., 1996, 19(4): 841-856.


Maiden et al., Proc. Natl. Acad. Sci. USA, 1998, 95: 3140-3145.






The amino acid sequences for each listed strain are as follows:








FA1090_519 <SEQ ID 3185>



MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRAMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


Z2491_519 <SEQ ID 3186>


MEFFIILLAAVVVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV01_519 <SEQ ID 3187>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV02_519 <SEQ ID 3188>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV03_519 <SEQ ID 3189>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV04_519 <SEQ ID 3190>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV05_519 <SEQ ID 3191>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV06_519ASS <SEQ ID 3192>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVFSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERK


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV07_519 <SEQ ID 3193>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV11_519 <SEQ ID 3194>


MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV12_519 <SEQ ID 3195>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV18_519 <SEQ ID 3196>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV19_519 <SEQ ID 3197>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV20_519ASS <SEQ ID 3198>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSM


ISAGMKIIDSSKTAK*


 


ZV21_519ASS <SEQ ID 3199>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV22_519ASS <SEQ ID 3200>


MEFFIILLAAVVVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAKIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV26_519 <SEQ ID 3201>


MEFFIILLAAVVVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV27_519 <SEQ ID 3202>


MEFFIILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV28_519 <SEQ ID 3203>


MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV29_519ASS <SEQ ID 3204>


MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSIVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREPEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSNKTAK*


 


ZV32_519 <SEQ ID 3205>


MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRAMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*


 


ZV96_519 <SEQ ID 3206>


MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSL


KEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIG


RMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAERE


KRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLR


LVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSL


ISAGMKIIDSSKTAK*






FIG. 22 shows the results of aligning the sequences of each of these strains. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. As is readily discernible, there is significant conservation among the various strains of ORF 225, further confirming its utility as an antigen for both vaccines and diagnostics.
Example 15
Table 6 lists several Neisseria strains which were used to assess the conservation of the sequence of ORF 919 among different strains.







TABLE 6







919 gene variability: List of used Neisseria strains











Identification





number
Strains
Source/reference











Group B











zm01
NG6/88
R. Moxon/Seiler et al., 1996



zm02
BZ198
R. Moxon/Seiler et al., 1996



zm03
NG3/88
R. Moxon/Seiler et al., 1996



zm04
297-0
R. Moxon/Seiler et al., 1996



zm05
1000
R. Moxon/Seiler et al., 1996



zm06
BZ147
R. Moxon/Seiler et al., 1996



zm07
BZ169
R. Moxon/Seiler et al., 1996



zm08n
528
R. Moxon/Seiler et al., 1996



zm09
NGP165
R. Moxon/Seiler et al., 1996



zm10
BZ133
R. Moxon/Seiler et al., 1996



zm11asbc
NGE31
R. Moxon/Seiler et al., 1996



zm12
NGF26
R. Moxon/Seiler et al., 1996



zm13
NGE28
R. Moxon/Seiler et al., 1996



zm14
NGH38
R. Moxon/Seiler et al., 1996



zm15
SWZ107
R. Moxon/Seiler et al., 1996



zm16
NGH15
R. Moxon/Seiler et al., 1996



zm17
NGH36
R. Moxon/Seiler et al., 1996



zm18
BZ232
R. Moxon/Seiler et al., 1996



zm19
BZ83
R. Moxon/Seiler et al., 1996



zm20
44/76
R. Moxon/Seiler et al., 1996



zm21
MC58
R. Moxon



zm96
2996
Our collection







Group A











zm22
205900
R. Moxon



zm23asbc
F6124
R. Moxon



z2491
Z2491
R. Moxon/Maiden et al., 1998







Group C











zm24
90/18311
R. Moxon



zm25
93/4286
R. Moxon







Others











zm26
A22 (group W)
R. Moxon/Maiden et al., 1998



zm27bc
E26 (group X)
R. Moxon/Maiden et al., 1998



zm28
860800 (group Y)
R. Moxon/Maiden et al., 1998



zm29asbc
E32 (group Z)
R. Moxon/Maiden et al., 1998



zm31asbc
N. lactamica
R. Moxon







Gonococcus











zm32asbc
Ng F62
R. Moxon/Maiden et al., 1998



zm33asbc
Ng SN4
R. Moxon



fa1090
FA1090
R. Moxon







References:



Seiler A. et al., Mol. Microbiol., 1996, 19(4): 841-856.



Maiden et al., Proc. Natl. Acad. Sci. USA, 1998, 95: 3140-3145.






The amino acid sequences for each listed strain are as follows:








FA1090 <SEQ ID 3207>



MKKHLLRSALYGIAAAILAACQSRSIQTFPQPDTSVINGPDRPAGIPDPAGTTVAGGGAV


YTVVPHLSMPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKRFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDGRRTERARFPIYGIPDDFISVPLPAGLRGGKN


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSGNEGPVGALGTPLMGEYAGA


IDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


Z2491 <SEQ ID 3208>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSVQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMQQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM01 <SEQ ID 3209>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM02 <SEQ ID 3210>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM03 <SEQ ID 3211>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM04 <SEQ ID 3212>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMQQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM05 <SEQ ID 3213>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLSCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM06 <SEQ ID 3214>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM07 <SEQ ID 3215>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM08N <SEQ ID 3216>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM09 <SEQ ID 3217>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM10 <SEQ ID 3218>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM11ASBC <SEQ ID 3219>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSVQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM12 <SEQ ID 3220>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM13 <SEQ ID 3221>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAEQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM14 <SEQ ID 3222>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSRNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM15 <SEQ ID 3223>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDLAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNHQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM16 <SEQ ID 3224>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPGRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM17 <SEQ ID 3225>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM18 <SEQ ID 3226>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM19 <SEQ ID 3227>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM20 <SEQ ID 3228>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM21 <SEQ ID 3229>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM22 <SEQ ID 3230>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSVQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMQQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM23ASBC <SEQ ID 3231>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTSKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGETAGK


MKEPGYVWQLLPNGMKPEYRP*


 


ZM24 <SEQ ID 3232>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM25 <SEQ ID 3233>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPAPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM26 <SEQ ID 3234>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSVQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMQQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM27BC <SEQ ID 3235>


MKKYLFRAALYGISAAILAACQSKSIQTFPQPDTSVINGPDRPAGIPDPAGTTVAGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGETAGK


MKEPGYVWQLLPNGMKPEYRP*


 


ZM28 <SEQ ID 3236>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM29ASBC <SEQ ID 3237>


MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATTHPITRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM31ASBC <SEQ ID 3238>


MKKHLFRAALYGIAAAILAACQSKSIQTFPQPDTSIIKGPDRPAGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYVFFRELAGSGNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM32ASBC <SEQ ID 3239>


MKKHLLRSALYGIAAAILAACQSRSIQTFPQPDTSVINGPDRPAGIPDPAGTTVAGGGAV


YTVVPHLSMPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKRFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDGRRTERARFPIYGIPDDFISVPLPAGLRGGKA


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSGGDGPVGALGTPLMGGYAGA


IDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM33ASBC <SEQ ID 3240>


MKKHLLRSALYGIAAAILAACQSRSIQTFPQPDTSVINGPDRPAGIPDPAGTTVAGGGAV


YTVVPHLSMPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPIHSFQAKRFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDGRRTERARFPIYGIPDDFISVPLPAGLRGGKN


LVRIRQTGKNSGTIDNAGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKSYMRQNPHKLAEVLGQNPSYIFFRELAGSGNEGPVGALGTPLMGEYAGA


IDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*


 


ZM96 <SEQ ID 3241>


MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPVGIPDPAGTTVGGGGAV


YTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFER


YFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKA


LVRIRQTGKNSGTIDNTGGTHTADLSRFPITARTTAIKGRFEGSRFLPYHTRNQINGGAL


DGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGRYMADKGYL


KLGQTSMQGIKAYMRQNPQRLAEVLGQNPSYIFFRELAGSSNDGPVGALGTPLMGEYAGA


VDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGK


QKTTGYVWQLLPNGMKPEYRP*






FIG. 23 shows the results of aligning the sequences of each of these strains. Dark shading indicates regions of homology, and gray shading indicates the conservation of amino acids with similar characteristics. As is readily discernible, there is significant conservation among the various strains of ORF 225, further confirming its utility as an antigen for both vaccines and diagnostics.
Example 16
Using the above-described procedures, the following oligonucleotide primers were employed in the polymerase chain reaction (PCR) assay in order to clone the ORFs as indicated:







TABLE 7







Oligonucleotides used for PCR to amplify complete or partial ORFs















Restriction


ORF
SEQ ID
primer
Sequence
sites





001
3300
Forward
CGCGGATCCCATATG-TGGATGGTGCTGGTCAT
BamHI-






NdeI



3301
Reverse
CCCGCTCGAG-TGCCGTCTTGTCCCAC
XhoI


003
3302
Forward
CGCGGATCCCATATG-GTCGTATTCGTGGC
BamHI-






NdeI



3303
Reverse
CCCGCTCGAG-AAAATCATGAACACGCGC
XhoI


005
3304
Forward
CGCGGATCCCATATG-GACAATATTGACATGT
BamHI-






NdeI



3305
Reverse
CCCGCTCGAG-CATCACATCCGCCCG
XhoI


006
3306
Forward
CGCGGATCCCATATG-CTGCTGGTGCTGG
BamHI-






NdeI



3307
Reverse
CCCGCTCGAG-AGTTCCGGCTTTGATGT
XhoI


007
3308
Forward
CGCGGATCCCATATG-GCCGACAACAGCATCAT
BamHI-






NdeI



3309
Reverse
CCCGCTCGAG-AAGGCGTTCATGATATAAG
XhoI


008
3310
Forward
CGCGGATCCCATATG-AACAACAGACATTTTG
BamHI-






NdeI



3311
Reverse
CCCGCTCGAG-CCTGTCCGGTAAAAGAC
XhoI


009
3312
Forward
CGCGGATCCCATATG-CCCCGCGCTGCT
BamHI-






NdeI



3313
Reverse
CCCGCTCGAG-TGGCTTTTGCCACGTTTT
XhoI


011
3314
Forward
CGCGGATCCCATATG-AAGACACACCGCAAG
BamHI-






NdeI



3315
Reverse
CCCGCTCGAG-GGCGGTCAGTACGGT
XhoI


012
3316
Forward
CGCGGATCCCATATG-CTCGCCCGTTGCC
BamHI-






NdeI



3317
Reverse
CCCGCTCGAG-AGCGGGGAAGAGGCAC
XhoI


013
3318
Forward
CGCGGATCCCATATG-CCTTTGACCATGCT
BamHI-






NdeI



3319
Reverse
CCCGCTCGAG-CTGATTCGGCAAAAAAATCT
XhoI


018
3320
Forward
CGCGGATCCCATATG-CAGCAGAGGCAGTT
BamHI-






NdeI



3321
Reverse
CCCGCTCGAG-GACGAGGCGAACGCC
XhoI


019
3322
Forward
AAAGAATTC-CTGCCAGCCGGCAAGACCCCGGC
Eco RI



3323
Reverse
AAACTGCAG-TCAGCGGGCGGGGACAATGCCCAT
Pst I


023
3324
Forward
AAAGAATTC-AAAGAATATTCGGCATGGCAGGC
Eco RI



3325
Reverse
AAACTGCAG-TTACCCCCAAATCACTTTAACTGA
Pst I


025
3326
Forward
AAAGAATTC-TGCGCCACCCAACAGCCTGCTCC
Eco RI



3327
Reverse
AAACTGCAG-TCAGAACGCGATATAGCTGTTCGG
Pst I


031
3328
Forward
CGCGGATCCCATATG-GTCTCCCTTCGCTT
BamHI-






NdeI



3329
Reverse
CCCGCTCGAG-ATGTAAGACGGGGACAAC
XhoI


032
3330
Forward
CGCGGATCCCATATG-CGGCGAAACGTGC
BamHI-






NdeI



3331
Reverse
CCCGCTCGAG-CTGGTTTTTTGATATTTGTG
XhoI


033
3332
Forward
CGCGGATCCCATATG-GCGGCGGCAGACA
BamHI-






NdeI



3333
Reverse
CCCGCTCGAG-ATTTGCCGCATCCCGAT
XhoI


034
3334
Forward
CGCGGATCCCATATG-GCCGAAAACAGCTACGG
BamHI-






NdeI



3335
Reverse
CCCGCTCGAG-TTTGACGATTTGGTTCAATT
XhoI


036
3336
Forward
CGCGGATCCCATATG-CTGAAGCCGTGCG
BamHI-






NdeI



3337
Reverse
CCCGCTCGAG-CCGGACTGCGTATCGG
XhoI


038
3338
Forward
CGCGGATCCCATATG-ACCGATTTCCGCCA
BamHI-






NdeI



3339
Reverse
CCCGCTCGAG-TTCTACGCCGTACTGCC
XhoI


039
3340
Forward
CGCGGATCCCATATG-CCGTCCGAACCGC
BamHI-






NdeI



3341
Reverse
CCCGCTCGAG-TAGGATGACGAGGTAGG
XhoI


041
3342
Forward
CGCGGATCCCATATG-TTCGTGCGCGAACCGC
BamHI-






NdeI



3343
Reverse
CCCGCTCGAG-GCCCAAAAACTCTTTCAAA
XhoI


042
3344
Forward
CGCGGATCCCATATG-ACGATGATTTGCTTGC
BamHI-






NdeI



3345
Reverse
CCCGCTCGAG-TTTGCAGCCTGCATTTGAC
XhoI


043
3346
Forward
AAAAAAGGTACC-ATGGTTGTTTCAAATCAAAATATC
Kpn I



3347
Reverse
AAACTGCAG-TTATTGCGCTTCACCTTCCGCCGC
Pst I


043a
3348
Forward
AAAAAAGGTACC-GCAAAAGTGCATGGCGGCTTGGACGGTGC
Kpn I



3349
Reverse
AAAAAACTGCAG-
Pst I





TTAATCCTGCAACACGAATTCGCCCGTCCG



044
3350
Forward
CGCGGATCCCATATG-CCGTCCGACTAGAG
BamHI-






NdeI



3351
Reverse
CCCGCTCGAG-ATGCGCTACGGTAGCCA
XhoI


046
3352
Forward
AAAGAATTC-ATGTCGGCAATGCTCCCGACAAG
Eco RI



3353
Reverse
AAACTGCAG-TCACTCGGCGACCCACACCGTGAA
Pst I


047
3354
Forward
CGCGGATCCCATATG-GTCATCATACAGGCG
BamHI-






NdeI



3355
Reverse
CCCGCTCGAG-TCCGAAAAAGCCCATTTTG
XhoI


048
3356
Forward
AAAGAATTC-ATGCTCAACAAAGGCGAAGAATTGCC
Eco RI



3357
Reverse
AAACTGCAG-TCAAGATTCGACGGGGATGATGCC
Pst I


049
3358
Forward
AAAGAATTC-ATGCGGGCGCAGGCGTTTGATCAGCC
Eco RI



3359
Reverse
AAACTGCAG-AAGGCGTATCTGAAAAAATGGCAG
Pst I


050
3360
Forward
CGCGGATCCCATATG-GGCGCGGGCTGG
BamHI-






NdeI



3361
Reverse
CCCGCTCGAG-AATCGGGCCATCTTCGA
XhoI


052
3362
Forward
AAAAAAGAATTC-ATGGCTTTGGTGGCGGAGGAAAC
Eco RI



3363
Reverse
AAAAAAGTCGAC-TCAGGCGGCGTTTTTCACCTTCCT
Sal I


052a
3364
Forward
AAAAAAGAATTC-GTGGCGGAGGAAACGGAAATATCCGC
Eco RI



3365
Reverse
AAAAAACTGCAG-TTAGCTGTTTTTGGAAACGCCGTCCAACCC
Pst I


073
3366
Forward
CGCGGATCCCATATG-TGTATGCCATATAAGAT
BamHI-






NdeI



3367
Reverse
CCCGCTCGAG-CACCGGATTGTCCGAC
XhoI


075
3368
Forward
CGCGGATCCCATATG-CCGTCTTACTTCATC
BamHI-






NdeI



3369
Reverse
CCCGCTCGAG-ATCACCAATGCCGATTATTT
XhoI


077a
3370
Forward
AAAAAAGAATTC-GGCGGCATTTTCATCGACACCTTCCT
Eco RI



3371
Reverse
AAAAAACTGCAG-TCAGACGAACATCTGCACAAACGCAAT
Pst I


080
3372
Forward
AAAGAATTC-GCGTCCGGGCTGGTTTGGTTTTACAATTC
Eco RI



3373
Reverse
AAACTGCAG-CTATTCTTCGGATTCTTTTTCGGG
Pst I


081
3374
Forward
AAAGAATTC-ATGAAACCACTGGACCTAAATTTCATCTG
Eco RI



3375
Reverse
AAACTGCAG-TCACTTATCCTCCAATGCCTC
Pst I


082
3376
Forward
AAAGAATTC-ATGTGGTTGTTGAAGTTGCCTGC
Eco RI



3377
Reverse
AAACTGCAG-TTACGCGGATTCGGCAGTTGG
Pst I


084
3378
Forward
AAAGAATTC-TATCACCCAGAATATGAATACGGCTACCG
Eco RI



3379
Reverse
AAACTGCAG-TTATACTTGGGCGCAACATGA
Pst I


085
3380
Forward
CGCGGATCCCATATG-GGTAAAGGGCAGGACT
BamHI-






NdeI



3381
Reverse
CCCGCTCGAG-CAAAGCCTTAAACGCTTCG
XhoI


086
3382
Forward
AAAAAAGGTACC-TATTTGGCATCAAAAGAAGGCGG
Kpn I



3383
Reverse
AAACTGCAG-TTACTCCACCCGATAACCGCG
Pst I


087
3384
Forward
AAAGAATTC-ATGGGCGGTAAAACCTTTATGC
Eco RI



3385
Reverse
AAACTGCAG-TTACGCCGCACACGCAATCGC
Pst I


087a
3386
Forward
AAAAAAGAATTC-AAGCTATTAGGCGTGCCGATTGTGATTCA
Eco RI



3387
Reverse
AAAAAACTGCAG-TTACGCCTGCAAGATGCCCAGCTTGCC
Pst I


088
3388
Forward
AAAAAAGAATTC-ATGTTTTTATGGCTCGCACATTTCAG
Eco RI



3389
Reverse
AAAAAACTGCAG-TCAGCGGATTTTGAGGGTACTCAAACC
Pst I


089
3390
Forward
CGCGGATCCCATATG-CCGCCCAAAATCAC
BamHI-






NdeI



3391
Reverse
CCCGCTCGAG-TGCGCATACCAAAGCCA
XhoI


090
3392
Forward
CGCGGATCCCATATG-CGCATAGTCGAGCA
BamHI-






NdeI



3393
Reverse
CCCGCTCGAG-AGCAAAACGGCGGTACG
XhoI


091
3394
Forward
AAAGAATTC-ATGGAAATACCCGTACCGCCGAGTCC
Eco RI



3395
Reverse
AAACTGCAG-TCAGCGCAGGGGGTAGCCCAAGCC
Pst I


092
3396
Forward
AAAGAATTC-ATGTTTTTTATTTCAATCCG
Eco RI



3397
Reverse
AAACTGCAG-TCAAATCTGTTTCGACAATGC
Pst I


093
3398
Forward
AAAGAATTC-ATGCAGAATTTTGGCAAAGTGGC
Eco RI



3399
Reverse
AAACTGCAG-CTATGGCTCGTCATACCGGGC
Pst I


094
3400
Forward
AAAGAATTC-ATGCCGTCACGGAAGCGCATCAACTC
Eco RI



3401
Reverse
AAACTGCAG-TTATCCCGGCCATACCGCCGAACA
Pst I


095
3402
Forward
AAAGAATTC-ATGTCCTTTCATTTGAACATGGACGG
Eco RI



3403
Reverse
AAACTGCAG-TCAACGCCGCAGGCACTAACGCCC
Pst I


096
3404
Forward
AAAGAATTC-ATGGCTCGTCATACCGGGCAGGG
Eco RI



3405
Reverse
AAACTGCAG-TCAAAGGAAAAGGCCGTCTGAAAAGCG
Pst I


097
3406
Forward
AAAGAATTC-ATGGACACTTCAAAACAAACACTGTTG
Eco RI



3407
Reverse
AAACTGCAG-TCAGCCCAAATACCAGAATTTCAG
Pst I


098
3408
Forward
AAAGAATTC-GATGAACGCAGCCCAGCATGGATACG
Eco RI



3409
Reverse
AAACTGCAG-TTACGACATTCTGATTTGGCA
Pst I


102
3410
Forward
AAAAAAGAATTC-GGCCTGATGATTTTGGAAGTCAACAC
Eco RI



3411
Reverse
AAAAAACTGCAG-TTATCCTTTAAATACGGGGACGAGTTC
Pst I


105
3412
Forward
CGCGGATCCCATATG-TCCGCAAACGAATACG
BamHI-






NdeI



3413
Reverse
CCCGCTCGAG-GTGTTCTGCCAGTTTCAG
XhoI


107
3414
Forward
AAAAAAGAATTC-
Eco RI





CTGATGATTTTGGAAGTCAACACCCATTATCC




3415
Reverse
AAAAAACTGCAG-TTATCCTTTAAATACGGGGACGAGTTC
Pst I


107b
3416
Forward
AAAAAAGAATTC-
Eco RI





GATACCCAAGCCCCCGCCGGCACAAACTACTG




3417
Reverse
AAAAAACTGCAG-
Pst I





TTACGCGTCGCCTTTAAAGTATTTGAGCAGGCTGGAGAC



108
3418
Forward
AAAGAATTC-ATGTTGCCGGGCTTCAACCG
Eco RI



3419
Reverse
AAACTGCAG-TTAGCGGTACAGGTGTTTGAAGCA
Pst I


108a
3420
Forward
AAAAAAGAATTC-GGTAACACATTCGGCAGCTTAGACGGTGG
Eco RI



3421
Reverse
AAACTGCAG-TTAGCGGTACAGGTGTTTGAAGCA
Pst I


109
3422
Forward
AAAGAATTC-ATGTATTATCGCCGGGTTATGGG
Eco RI



3423
Reverse
AAACTGCAG-CTAGCCCAAAGATTTGAAGTGTTC
Pst I


111
3424
Forward
CGCGGATCCCATATG-TGTTCGGAACAAACCGC
BamHI-






NdeI



3425
Reverse
CCCGCTCGAG-GCGGAGCAGTTTTTCAAA
XhoI


114
3426
Forward
CGCGGATCCCATATG-GCTTCCATCACTTCGC
BamHI-






NdeI



3427
Reverse
CCCGCTCGAG-CATCCGCGAAATCGTC
XhoI


117
3428
Forward
AAAAAAGGTACC-ATGGTCGAAGAACTGGAACTGCTG
Kpn I



3429
Reverse
AAACTGCAG-TTAAAGCCGGGTAACGCTCAATAC
Pst I


118
3430
Forward
AAAGTCGACATGTGTGAGTTCAAGGATATTATAAG
Sal I



3431
Reverse
AAAGCATGC-CTATTTTTTGTTGTAATAATCAAATC
Sph I


121
3432
Forward
CGCGGATCCCATATG-GAAACACAGCTTTACAT
BamHI-






NdeI



3433
Reverse
CCCGCTCGAG-ATAATAATATCCCGCGCCC
XhoI


122
3434
Forward
CGCGGATCCCATATG-GTCATGATTAAAATCCGCA
BamHI-






NdeI



3435
Reverse
CCCGCTCGAG-AATCTTGGTAGATTGGATTT
XhoI


125
3436
Forward
AAAGAATTC-ATGTCGGGCAATGCCTCCTCTCC
Eco RI



3437
Reverse
AAACTGCAG-TCACGCCGTTTCAAGACG
Pst I


125a
3438
Forward
AAAAAAGAATTC-ACGGCAGGCAGCACCGCCGCACAGGTTTC
Eco RI



3439
Reverse
AAAAAACTGCAG-
Pst I





TTATTTTGCCACGTCGGTTTCTCCGGTGAACAACGC



126
3440
Forward
CGCGGATCCCATATG-CCGTCTGAAACCC
BamHI-






NdeI



3441
Reverse
CCCGCTCGAG-ATATTCCGCCGAATGCC
XhoI


127
3442
Forward
AAAGAATTC-ATGGAAATATGGAATATGTTGGACACTTG
Eco RI



3443
Reverse
AAACTGCAG-TTAAAGTGTTTCGGAGCCGGC
Pst I


127a
3444
Forward
AAAAAAGAATTC-AAGGAACTGATTATGTGTCTGTCGGG
Eco RI



3445
Reverse
AAACTGCAG-TTAAAGTGTTTCGGAGCCGGC
Pst I


128
3446
Forward
CGCGGATCCCATATG-ACTGACAACGCACT
BamHI-






NdeI



3447
Reverse
CCCGCTCGAG-GACCGCGTTGTCGAAA
XhoI


130
3448
Forward
CGCGGATCCCATATG-AAACAACTCCGCGA
BamHI-






NdeI



3449
Reverse
CCCGCTCGAG-GAATTTTGCACCGGATTG
XhoI


132
3450
Forward
AAAGAATTC-ATGGAACCCTTCAAAACCTTAATTTG
Eco RI



3451
Reverse
AAAAAACTGCAG-TCACCATGTCGGCATTTGAAAAAC
Pst I


134
3452
Forward
CGCGGATCCCATATG-TCCCAAGAAATCCTC
BamHI-






NdeI



3453
Reverse
CCCGCTCGAG-CAGTTTGACCGAATGTTC
XhoI


135
3454
Forward
CGCGGATCCCATATG-AAATACAAAAGAATCGTATT
BamHI-






NdeI



3455
Reverse
CCCGCTCGAG-AAATTCGGTCAGAAGCAGG
XhoI


137
3456
Forward
AAAAAAGGTACC-ATGATTACCCATCCCCAATTCGATCC
Kpn I



3457
Reverse
AAAAAACTGCAG-TCAGTGCTGTTTTTTCATGCCGAA
Pst I


137a
3458
Forward
AAAAAAGAATTC-GGCCGCAAACACGGCATCGGCTTCCT
Eco RI



3459
Reverse
AAAAAACTGCAG-TTAAGCGGGATGACGCGGCAGCATACC
Pst I


138
3460
Forward
AAAAAAGAATTC-AACTCAGGCGAAGGAGTGCTTGTGGC
Eco RI



3461
Reverse
AAAAAATCTAGA-TCAGTTTAGGGATAGCAGGCGTAC
Xba I


141
3462
Forward
AAAGAATTC-ATGAGCTTCAAAACCGATGCCGAAATCGC
Eco RI



3463
Reverse
AAACTGCAG-TCAGAACAAGCCGTGAATCACGCC
Pst I


142
3464
Forward
CGCGGATCCCATATG-CGTGCCGATTTCATG
BamHI-






NdeI



3465
Reverse
CCCGCTCGAG-AAACTGCTGCACATGGG
XhoI


143
3466
Forward
AAAAAAGAATTC-
Eco RI





ATGCTCAGTTTCGGCTTTCTCGGCGTTCAGAC




3467
Reverse
AAAAAACTGCAG-TCAAACCCCGCCGTGTGTTTCTTTAAT
Pst I


144
3468
Forward
AAAAAAGAATTC-GGTCTGATCGACGGGCGTGCCGTAAC
Eco RI



3469
Reverse
AAAAAATCTAGA-TCGGCATCGGCCGGCATATGTCCG
Xba I


146
3470
Forward
AAAAAAGAATTC-
Eco RI





CGCCAAGTCGTCATTGACCACGACAAAGTC




3471
Reverse
AAAAAACTGCAG-TTAGGCATCGGCAAATAGGAAACTGGG
Pst I


147
3472
Forward
AAAAAAGAATTC-ACTGAGCAATCGGTGGATTTGGAAAC
Eco RI



3473
Reverse
AAAAAATCTAGA-TTAGGTAAAGCTGCGGCCCATTTGCGG
Xba I


148
3474
Forward
AAAAAAGAATTC-
Eco RI





ATGGCGTTAAAAACATCAAACTTGGAACACGC




3475
Reverse
AAAAAATCTAGA-TCAGCCCTTCATACAGCCTTCGTTTTG
Xba I


149
3476
Forward
CGCGGATCCCATATG-CTGCTTGACAACAAAGT
BamHI-






NdeI



3477
Reverse
CCCGCTCGAG-AAACTTCACGTTCACGCC
XhoI


150
3478
Forward
CGCGGATCCCATATG-CAGAACACAAATCCG
BamHI-






NdeI



3479
Reverse
CCCGCTCGAG-ATAAACATCACGCTGATAGC
XhoI


151
3480
Forward
AAAAAAGAATTC-
Eco RI





ATGAAACAAATCCGCAACATCGCCATCATCGC




3481
Reverse
AAAAAACTGCAG-TCAATCCAGCTTTTTAAAGTGGCGGCG
Pst I


152
3482
Forward
AAAAAAGAATTC-
Eco RI





ATGAAAAACAAAACCAAAGTCTGGGACCTCCC




3483
Reverse
AAAAAACTGCAG-TCAGGACAGGAGCAGGATGGCGGC
Pst I


153
3484
Forward
AAAAAAGAATTC-ATGGCGTTTGCTTACGGTATGAC
Eco RI



3485
Reverse
AAAAAACTGCAG-TCAGTCATGTTTTTCCGTTTCATT
Pst I


153a
3486
Forward
AAAAAAGAATTC-CGGACTTCGGTATCGGTTCCCCAGCATTG
Eco RI



3487
Reverse
AAAAAACTGCAG-
Pst I





TTACGCCGACGAAATACTCAGACTTTTCGG



154
3488
Forward
CGCGGATCCCATATG-ACTGACAACAGCCC
BamHI-






NdeI



3489
Reverse
CCCGCTCGAG-TCGGCTTCCTTTCGGG
XhoI


155
3490
Forward
AAAAAAGAATTC-ATGAAAATCGGTATCCCACGCGAGTC
Eco RI



3491
Reverse
AAAAAACTGCAG-TTACCCTTTCTTAAACATATTCAGCAT
Pst I


156
3492
Forward
AAAAAAGAATTC-GCACAGCAAAACGGTTTTGAAGC
Eco RI



3493
Reverse
AAAAAACTGCAG-TCAAGCAGCCGCGACAAACAGCCC
Pst I


157
3494
Forward
CGCGGATCCCATATG-AGGAACGAGGAAAAAC
BamHI-






NdeI



3495
Reverse
CCCGCTCGAG-AAAACACAATATCCCCGC
XhoI


158
3496
Forward
AAAAAAGAATTC-GCGGAGCAGTTGGCGATGGCAAATTCTGC
Eco RI



3497
Reverse
AAAAAATCTAGA-TTATCCACAGAGATTGTTTCCCAGTTC
Xba I


160
3498
Forward
CGCGGATCCCATATG-GACATTCTGGACAAAC
BamHI-






NdeI



3499
Reverse
CCCGCTCGAG-TTTTTGCCCGCCTTCTTT
XhoI


163
3500
Forward
AAAAAAGGTACC-ACCGTGCCGGATCAGGTGCAGATGTG
Kpn I



3501
Reverse
AAAAAATCTAGA-TTACTCTGCCAATTCCACCTGCTCGTG
Xba I


163a
3502
Forward
AAAAAAGAATTC-CGGCTGGTGCAGATAATGAGCCAGAC
Eco RI



3503
Reverse
AAAAAATCTAGA-TTACTCTGCCAATTCCACCTGCTCGTG
Xba I


164
3504
Forward
CGCGGATCCCATATG-AACCGGACTTATGCC
BamHI-






NdeI



3505
Reverse
CCCGCTCGAG-TTTGTTTCCGTCAAACTGC
XhoI


165
3506
Forward
CGCGGATCCGCTAGC-GCTGAAGCGACAGACG
BamHI-






NheI



3507
Reverse
CCCGCTCGAG-AATATCCAATACTTTCGCG
XhoI


206
3508
Forward
CGCGGATCCCATATG-AAACACCGCCAACCGA
BamHI-






NdeI



3509
Reverse
CCCGCTCGAG-TTCTGTAAAAAAAGTATGTGC
XhoI


209
3510
Forward
CGCGGATCCCATATG-CTGCGGCATTTAGGA
BamHI-






NdeI



3511
Reverse
CCCGCTCGAG-TACCCCTGAAGGCAAC
XhoI


211
3512
Forward
AAAAAAGAATTC-ATGTTGCGGGTTGCTGCTGC
Eco RI



3513
Reverse
AAAAAACTGCAG-CTATCCTGCGGATTGGCATTGAAA
Pst I


212
3514
Forward
CGCGGATCCCATATG-GACAATCTCGTATGG
BamHI-






NdeI



3515
Reverse
CCCGCTCGAG-AGGGGTTAGATCCTTCC
XhoI


215
3516
Forward
CGCGGATCCCATATG-GCATGGTTGGGTCGT
BamHI-






NdeI



3517
Reverse
CCCGCTCGAG-CATATCTTTTGTATCATAAATC
XhoI


216
3518
Forward
CGCGGATCCCATATG-GCAATGGCAGAAAACG
BamHI-






NdeI



3519
Reverse
CCCGCTCGAG-TACAATCCGTGCCGCC
XhoI


217
3520
Forward
CGCGGATCCCATATG-GCGGATGACGGTGTG
BamHI-






NdeI



3521
Reverse
CCCGCTCGAG-ACCCCGAATATCGAATCC
XhoI


218
3522
Forward
CGCGGATCCCATATG-GTCGCGGTCGATC
BamHI-






NdeI



3523
Reverse
CCCGCTCGAG-TAACTCATAGAATCCTGC
XhoI


219
3524
Forward
CGCGGATCCGCTAGC-ACGGCAAGGTTAAG
BamHI-






NheI



3525
Reverse
CCCGCTCGAG-TTTAAACCATCTCCTCAAAAC
XhoI


223
3526
Forward
CGCGGATCCCATATG-GAATTCAGGCACCAAGTA
BamHI-






NdeI



3527
Reverse
CCCGCTCGAG-GGCTTCCCGCGTGTC
XhoI


225
3528
Forward
CGCGGATCCCATATG-GACGAGTTGACCAACC
BamHI-






NdeI



3529
Reverse
CCCGCTCGAG-GTTCAGAAAGCGGGAC
XhoI


226
3530
Forward
AAAGAATTC-CTTGCGATTATCGTGCGCACGCG
Eco RI



3531
Reverse
AAACTGCAG-TCAAAATCCCAAAACGGGGAT
Pst I


228
3532
Forward
CGCGGATCCCATATG-TCGCAAGAAGCCAAACAG
BamHI-






NdeI



3533
Reverse
CCCGCTCGAG-TTTGGCGGCATCTTTCAT
XhoI


229
3534
Forward
CGCGGATCCCATATG-CAAGAGGTTTTGCCC
BamHI-






NdeI



3535
Reverse
CCCGCTCGAG-ACACAATATAGCGGATGAAC
XhoI


230
3536
Forward
CGCGGATCCCATATG-CATCCGGGTGCCGAC
BamHI-






NdeI



3537
Reverse
CCCGCTCGAG-AAGTTTGGCGGCTTCGG
XhoI


232
3538
Forward
AAAAAAGAATTC-ATGTACGCTAAAAAAGGCGGTTTGGG
Eco RI



3539
Reverse
AAAAAACTGCAG-TCAAGGTTTTTTCCTGATTGCCGCCGC
Pst I


232a
3540
Forward
AAAAAAGAATTC-GCCAAGGCTGCCGATACACAAATTGA
Eco RI



3541
Reverse
AAAAAACTGCAG-TTAAACATTGTCGTTGCCGCCCAGATG
Pst I


233
3542
Forward
CGCGGATCCCATATG-GCGGACAAACCCAAG
BamHI-






NdeI



3543
Reverse
CCCGCTCGAG-GACGGCATTGAGCAG
XhoI


234
3544
Forward
CGCGGATCCCATATG-GCCGTTTCACTGACCG
BamHI-






NdeI



3545
Reverse
GCCCAAGCTT-ACGGTTGGATTGCCATG
Hind III


235
3546
Forward
CGCGGATCCCATATG-GCCTGCCAAGTTCAAA
BamHI-






NdeI



3547
Reverse
CCCGCTCGAG-TTTGGGCTGCTCTTC
XhoI


236
3548
Forward
CGCGGATCCCATATG-GCGCGTTTCGCCTT
BamHI-






NdeI



3549
Reverse
CCCGCTCGAG-ATGGGTCGCGCGCCGT
XhoI


238
3550
Forward
CGCGGATCCGCTAGC-AACGGTTTGGATGCCCG
BamHI-






NheI



3551
Reverse
CCCGCTCGAG-TTTGTCTAAGTTCCTGATATG
XhoI


239
3552
Forward
CCGGAATTCTACATATG-CTCCACCATAAAGGTATTG
EcoRI-






NdeI



3553
Reverse
CCCGCTCGAG-TGGTGAAGAGCGGTTTAG
XhoI


240
3554
Forward
CGCGGATCCCATATG-GACGTTGGACGATTTC
BamHI-






NdeI



3555
Reverse
CCCGCTCGAG-AAACGCCATTACCCGATG
XhoI


241
3556
Forward
CCGGAATTCTACATATG-CCAACACGTCCAACT
EcoRI-






NdeI



3557
Reverse
CCCGCTCGAG-GAATGCGCCTGTAATTAATC
XhoI


242
3558
Forward
CGCGGATCCCATATG-ATCGGCAAACTTGTTG
BamHI-






NdeI



3559
Reverse
GCCCAAGCTT-ACCGATACGGTCGCAG
HindIII


243
3560
Forward
CGCGGATCCCATATG-ACGATTTTTTCGATGCTGC
BamHI-






NdeI



3561
Reverse
CCCGCTCGAG-CGACTTGGTTACCGCG
XhoI


244
3562
Forward
CGCGGATCCCATATG-CCGTCTGAAGCCC
BamHI-






NdeI



3563
Reverse
CCCGCTCGAG-TTTTTTCGGTAGGGGATTT
XhoI


246
3564
Forward
CGCGGATCCCATATG-GACATCGGCAGTGC
BamHI-






NdeI



3565
Reverse
CCCGCTCGAG-CCCGCGCTGCTGGAG
XhoI


247
3566
Forward
CGCGGATCCCATATG-GTCGGATCGAGTTAC
BamHI-






NdeI



3567
Reverse
CCCGCTCGAG-AAGTGTTCTGTTTGCGCA
XhoI


248
3568
Forward
CGCGGATCCCATATG-CGCAAACAGAACACT
BamHI-






NdeI



3569
Reverse
CCCGCTCGAG-CTCATCATTATTGCTAACA
XhoI


249
3570
Forward
CGCGGATCCCATATG-AAGAATAATGATTGCTTC
BamHI-






NdeI



3571
Reverse
CCCGCTCGAG-TTCCCGACCTCCGAC
XhoI


251
3572
Forward
CGCGGATCCCATATG-CGTGCTGCGGTAGT
BamHI-






NdeI



3573
Reverse
CCCGCTCGAG-TACGAAAGCCGGTCGTG
XhoI


253
3574
Forward
AAAAAAGAATTC-ATGATTGACAGGAACCGTATGCTGCG
Eco RI



3575
Reverse
AAAAAACTGCAG-TTATTGGTCTTTCAAACGCCCTTCCTG
Pst I


253a
3576
Forward
AAAAAAGAATTC-AAAATCCTTTTGAAAACAAGCGAAAACGG
Eco RI



3577
Reverse
AAAAAACTGCAG-TTATTGGTCTTTCAAACGCCCTTCCTG
Pst I


254
3578
Forward
AAAAAAGAATTC-ATGTATACAGGCGAACGCTTCAATAC
Eco RI



3579
Reverse
AAAAAATCTAGA-TCAGATTACGTAACCGTACACGCTGAC
Xba I


255
3580
Forward
CGCGGATCCCATATG-GCCGCGTTGCGTTAC
BamHI-






NdeI



3581
Reverse
CCCGCTCGAG-ATCCGCAATACCGACCAG
XhoI


256
3582
Forward
CGCGGATCCGCTAGC-TTTTAACACCGCCGGAC
BamHI-






NheI



3583
Reverse
CCCGCTCGAG-ACGCCTGTTTGTGCGG
XhoI


257
3584
Forward
CGCGGATCCCATATG-GCGGTTTCTTTCCTG
BamHI-






NdeI



3585
Reverse
CCCGCTCGAG-GCGCGTGAATATCGCG
XhoI


258
3586
Forward
AAAAAAGAATTC-GATTATTTCTGGTGGATTGTTGCGTTCAG
Eco RI



3587
Reverse
AAAAAACTGCAG-CTACGCATAAGTTTTTACCGTTTTTGG
Pst I


258a
3588
Forward
AAAAAAGAATTC-GCGAAGGCGGTGGCGCAAGGCGA
Eco RI



3589
Reverse
AAAAAACTGCAG-CTACGCATAAGTTTTTACCGTTTTTGG
Pst I


259
3590
Forward
CGCGGATCCCATATG-GAAGAGCTGCCTCCG
BamHI-






NdeI



3591
Reverse
CCCGCTCGAG-GGCTTTTCCGGCGTTT
XhoI


260
3592
Forward
CGCGGATCCCATATG-GGTGCGGGTATGGT
BamHI-






NdeI



3593
Reverse
CCCGCTCGAG-AACAGGGCGACACCCT
XhoI


261
3594
Forward
AAAAAAGAATTC-CAAGATACAGCTCGGGCATTCGC
Eco RI



3595
Reverse
AAAAAACTGCAG-TCAAACCAACAAGCCTTGGTCACT
Pst I


263
3596
Forward
CGCGGATCCCATATG-GCACGTTTAACCGTA
BamHI-






NdeI



3597
Reverse
CCCGCTCGAG-GGCGTAAGCCTGCAATT
XhoI


264
3598
Forward
AAAAAAGGTACC-GCCGACGCAGTGGTCAAGGCAGAA
Kpn I



3599
Reverse
AAACTGCAG-TCAGCCGGCGGTCAATACCGCCCG
Pst I


265
3600
Forward
AAAAAAGAATTC-GCGGAGGTCAAGAGAAGGTGTTTG
Eco RI



3601
Reverse
AAAAAACTGCAG-TTACGAATACGTCGTCAAAATGGG
Pst I


266
3602
Forward
AAAGAATTC-CTCATCTTTGCCAACGCCCCCTTC
Eco RI



3603
Reverse
AAACTGCAG-CTATTCCCTGTTGCGCGTGTGCCA
Pst I


267
3604
Forward
AAAGAATTC-TTCTTCCGATTCGATGTTAATCG
Eco RI



3605
Reverse
AAACTGCAG-TTAGTAAAAACCTTTCTGCTTGGC
Pst I


269
3606
Forward
AAAGAATTC-TGCAAACCTTGCGCCACGTGCCC
Eco RI



3607
Reverse
AAACTGCAG-TTACGAAGACCGCAACGAAAGGCAGAG
Pst I


269a
3608
Forward
AAAAAAGAATTC-GACTTTATCCAAAACACGGCTTCGCC
Eco RI



3609
Reverse
AAACTGCAG-TTACGAAGACCGCAACGAAAGGCAGAG
Pst I


270
3610
Forward
AAAGAATTC-GCCGTCAAGCTCGTTTTGTTGCAATG
Eco RI



3611
Reverse
AAACTGCAG-TTATTCGGCGGTAAATGCCGTCTG
Pst I


271
3612
Forward
CGCGGATCCCATATG-CCTGTGTGCAGCTCGAC
BamHI-






NdeI



3613
Reverse
CCCGCTCGAG-TCCCAGCCCCGTGGAG
XhoI


272
3614
Forward
AAAGAATTC-ATGACCGCAAAGGAAGAACTGTTCGC
Eco RI



3615
Reverse
AAACTGCAG-TCAGAGCAGTTCCAAATCGGGGCT
Pst I


273
3616
Forward
AAAGAATTC-ATGAGTCTTCAGGCGGTATTTATATACCC
Eco RI



3617
Reverse
AAACTGCAG-TTACGCGTAAGAAAAAACTGC
Pst I


274
3618
Forward
CGCGGATCCCATATG-ACAGATTTGGTTACGGAC
BamHI-






NdeI



3619
Reverse
CCCGCTCGAG-TTTGCTTTCAGTATTATTGAA
XhoI


276
3620
Forward
AAAAAAGAATTC-
Eco RI





ATGATTTTGCCGTCGTCCATCACGATGATGCG




3621
Reverse
AAAAAACTGCAG-CTACACCACCATCGGCGAATTTATGGC
Pst I


277
3622
Forward
AAAAAAGAATTC-ATGCCCCGCTTTGAGGACAAGCTCGTAGG
Eco RI



3623
Reverse
AAAAAACTGCAG-TCATAAGCCATGCTTACCTTCCAACAA
Pst I


277a
3624
Forward
AAAAAAGAATTC-GGGGCGGCGGCTGGGTTGGACGTAGG
Eco RI



3625
Reverse
AAAAAACTGCAG-TCATAAGCCATGCTTACCTTCCAACAA
Pst I


278
3626
Forward
AAAAAAGGTACC-GTCAAAGTTGTATTAATCGGGCCTTTGCC
Kpn I



3627
Reverse
AAAAAACTGCAG-TCATTCAACCATATCAAATCTGCC
Pst I


278a
3628
Forward
AAAAAAGAATTC-AAAACTCTCCTAATTCGTCATAGTCG
Eco RI



3629
Reverse
AAAAAACTGCAG-TCATTCAACCATATCAAATCTGCC
Pst I


279
3630
Forward
CGCGGATCCCATATG-TTGCCTGCAATCACGATT
BamHI-






NdeI



3631
Reverse
CCCGCTCGAG-TTTAGAAGCGGGCGGCAA
XhoI


280
3632
Forward
AAAAAAGGTACC-GCCCCCCTGCCGGTTGTAACCAG
Kpn I



3633
Reverse
AAAAAACTGCAG-TTATTGCTTCATCGCGTTGGTCAAGGC
Pst I


281
3634
Forward
AAAAAAGAATTC-GCACCCGTCGGCGTATTCCTCGTCATGCG
Eco RI



3635
Reverse
AAAAAATCTAGA-GGTCAGAATGCCGCCTTCTTTGCCGAG
Xba I


281a
3636
Forward
AAAAAAGAATTC-TCCTACCACATCGAAATTCCTTCCGG
Eco RI



3637
Reverse
AAAAAATCTAGA-GGTCAGAATGCCGCCTTCTTTGCCGAG
Xba I


282
3638
Forward
AAAAAAGAATTC-CTTTACCTTGACCTGACCAACGGGCACAG
Eco RI



3639
Reverse
AAAAAACTGCAG-TCAACCTGCCAGTTGCGGGAATATCGT
Pst I


283
3640
Forward
CGCGGATCCCATATG-GCCGTCTTTACTTGGAAG
BamHI-






NdeI



3641
Reverse
CCCGCTCGAG-ACGGCAGTATTTGTTTACG
XhoI


284
3642
Forward
CGCGGATCCCATATG-TTTGCCTGCAAAAGAATCG
BamHI-






NdeI



3643
Reverse
CCCGCTCGAG-CCGACTTTGCAAAAACTG
XhoI


286
3644
Forward
CGCGGATCCCATATG-GCCGACCTTTCCGAAAA
BamHI-






NdeI



3645
Reverse
CCCGCTCGAG-GAAGCGCGTTCCCAAG
XhoI


287
3646
Forward
CCGGAATTCTAGCTAGC-CTTTCAGCCTGCGGG
EcoRI-






NheI



3647
Reverse
CCCGCTCGAG-ATCCTGCTCTTTTTTGCC
XhoI


288
3648
Forward
CGCGGATCCCATATG-CACACCGGACAGG
BamHI-






NdeI



3649
Reverse
CCCGCTCGAG-CGTATCAAAGACTTGCGT
XhoI


290
3650
Forward
CGCGGATCCCATATG-GCGGTTTGGGGCGGA
BamHI-






NdeI



3651
Reverse
CCCGCTCGAG-TCGGCGCGGCGGGC
XhoI


292
3652
Forward
CGCGGATCCCATATG-TGCGGGCAAACGCCC
BamHI-






NdeI



3653
Reverse
CCCGCTCGAG-TTGATTTTTGCGGATGATTT
XhoI


294
3654
Forward
AAAAAAGAATTC-GTCTGGTCGATTCGGGTTGTCAGAAC
Eco RI



3655
Reverse
AAAAAACTGCAG-TTACCAGCTGATATAAAACATCGCTTT
Pst I


295
3656
Forward
CGCGGATCCCATATG-AACCGGCCGGCCTCC
BamHI-






NdeI



3657
Reverse
CCCGCTCGAG-CGATATTTGATTCCGTTGC
XhoI


297
3658
Forward
AAAAAAGAATTC-GCATACATTGCTTCGACAGAGAG
Eco RI



3659
Reverse
AAAAAACTGCAG-TCAATCCGATTGCGACACGGT
Pst I


298
3660
Forward
AAAAAAGAATTC-CTGATTGCCGTGTGGTTCAGCCAAAACCC
Eco RI



3661
Reverse
AAAAAACTGCAG-TCATGGCTGTGTACTTGATGGTTGCGT
Pst I


299
3662
Forward
CGCGGATCCGCTAGC-CTACCTGTCGCCTCCG
BamHI-






NheI



3663
Reverse
CCCGCTCGAG-TTGCCTGATTGCAGCGG
XhoI


302
3664
Forward
AAAAAAGAATTC-ATGAGTCAAACCGATACGCAACG
Eco RI



3665
Reverse
AAAAAACTGCAG-TTAAGGTGCGGGATAGAATGTGGGCGC
Pst I


305
3666
Forward
AAAAAAGGTACC-GAATTTTTACCGATTTCCAGCACCGGA
Kpn I



3667
Reverse
AAAAAACTGCAG-TCATTCCCAACTTATCCAGCCTGACAG
Pst I


305a
3668
Forward
AAAAAAGGTACC-TCCCGTTCGGGCAGTACGATTATGGG
Kpn I



3669
Reverse
AAAAAACTGCAG-TTACAAACCGACATCATGCAGGGTGAA
Pst I


306
3670
Forward
CGCGGATCCCATATG-TTTATGAACAAATTTTCCC
BamHI-






NdeI



3671
Reverse
CCCGCTCGAG-CCGCATCGGCAGAC
XhoI


308
3672
Forward
CGCGGATCCCATATG-TTAAATCGGGTATTTTATC
BamHI-






NdeI



3673
Reverse
CCCGCTCGAG-ATCCGCCATTCCCTGC
XhoI


311
3674
Forward
AAAAAAGGTACC-ATGTTCAGTTTTGGCTGGGTGTTT
Kpn I



3675
Reverse
AAACTGCAG-ATGTTCATATTCCCTGCCTTCGGC
Pst I


312
3676
Forward
AAAAAAGGTACC-ATGAGTATCCCATCCGGCGAAATT
Kpn I



3677
Reverse
AAACTGCAG-TCAGTTTTTCATCGATTGAACCGG
Pst I


313
3678
Forward
AAAAAAGAATTC-ATGGACGACCCGCGCACCTACGGATC
Eco RI



3679
Reverse
AAAAAACTGCAG-TCAGCGGCTGCCGCCGATTTTGCT
Pst I


401
3680
Forward
CGCGGATCCCATATG-AAGGCGGCAACACAGC
BamHI-






NdeI



3681
Reverse
CCCGCTCGAG-CCTTACGTTTTTCAAAGCC
XhoI


402
3682
Forward
AAAAAAGAATTC-GTGCCTCAGGCATTTTCATTTACCCTTGC
Eco RI



3683
Reverse
AAAAAATCTAGA-TTAAATCCCTCTGCCGTATTTGTATTC
Xba I


402a
3684
Forward
AAAAAAGAATTC-AGGCTGATTGAAAACAAACACGG
Eco RI



3685
Reverse
AAAAAATCTAGA-TTAAATCCCTCTGCCGTATTTGTATTC
Xba I


406
3686
Forward
CGCGGATCCCATATG-TGCGGGACACTGACAG
BamHI-






NdeI



3687
Reverse
CCCGCTCGAG-AGGTTGTCCTTGTCTATG
XhoI


501
3688
Forward
CGCGGATCCCATATG-GCAGGCGGAGATGGC
BamHI-






NdeI



3689
Reverse
CCCGCTCGAG-GGTGTGATGTTCACCC
XhoI


502
3690
Forward
CGCGGATCCCATATG-GTAGACGCGCTTAAGCA
BamHI-






NdeI



3691
Reverse
CCCGCTCGAG-AGCTGCATGGCGGCG
XhoI


503
3692
Forward
CGCGGATCCCATATG-TGTTCGGGGAAAGGCG
BamHI-






NdeI



3693
Reverse
CCCGCTCGAG-CCGCGCATTCCTCGCA
XhoI


504
3694
Forward
CGCGGATCCCATATG-AGCGATATTGAAGTGACG
BamHI-






NdeI



3695
Reverse
GCCCAAGCTT-TGATTCAAGTCCTTGCCG
HindIII


505
3696
Forward
CGCGGATCCCATATG-TTTCGTTTACAATTCAGG
BamHI-






NdeI



3697
Reverse
CCCGCTCGAG-CGGCGTTTTATAGCGG
XhoI


510
3698
Forward
CGCGGATCCCATATG-CCTTCGCGGACAC
BamHI-






NdeI



3699
Reverse
CCCGCTCGAG-GCGCACTGGCAGCG
XhoI


512
3700
Forward
CGCGGATCCCATATG-GGACATGAAGTAACGGT
BamHI-






NdeI



3701
Reverse
CCCGCTCGAG-AGGAATAGCCTTTGACG
XhoI


515
3702
Forward
CGCGGATCCCATATG-GAGGAAATAGCCTTCGA
BamHI-






NdeI



3703
Reverse
CCCGCTCGAG-AAATGCCGCAAAGCATC
XhoI


516
3704
Forward
CGCGGATCCCATATG-TGTACGTTGATGTTGTGG
BamHI-






NdeI



3705
Reverse
CCCGCTCGAG-TTTGCGGGCGGCATC
XhoI


517
3706
Forward
CGCGGATCCCATATG-GGTAAAGGTGTGGAAATA
BamHI-






NdeI



3707
Reverse
CCCGCTCGAG-GTGCGCCCAGCCGT
XhoI


518
3708
Forward
AAAGAATTC-GCTTTTTTACTGCTCCGACCGGAAGG
Eco RI



3709
Reverse
AAACTGCAG-TCAAATTTCAGACTCTGCCAC
Pst I


519
3710
Forward
CGCGGATCCCATATG-TTCAAATCCTTTGTCGTCA
BamHI-






NdeI



3711
Reverse
CCCGCTCGAG-TTTGGCGGTTTTGCTGC
XhoI


520
3712
Forward
CGCGGATCCCATATG-CCTGCGCTTCTTTCA
BamHI-






NdeI



3713
Reverse
CCCGCTCGAG-ATATTTACATTTCAGTCGGC
XhoI


521
3714
Forward
CGCGGATCCCATATG-GCCAAAATCTATACCTGC
BamHI-






NdeI



3715
Reverse
CCCGCTCGAG-CATACGCCCCAGTTCC
XhoI


522
3716
Forward
CGCGGATCCCATATG-ACTGAGCCGAAACAC
BamHI-






NdeI



3717
Reverse
GCCCAAGCTT-TTCTGATTTCAAATCGGCA
HindIII


523
3718
Forward
CGCGGATCCCATATG-GCTCTGCTTTCCGCG
BamHI-






NdeI



3719
Reverse
CCCGCTCGAG-AGGGTGTGTGATAATAAGAAG
XhoI


525
3720
Forward
CGCGGATCCCATATG-GCCGAAATGGTTCAAATC
BamHI-






NdeI



3721
Reverse
CCCGCTCGAG-GCCCGTGCATATCATAAA
XhoI


527
3722
Forward
AAAGAATTC-TTCCCTCAATGTTGCCGTTTTCG
Eco RI



3723
Reverse
AAACTGCAG-TTATGCTAAACTCGAAACAAATTC
Pst I


529
3724
Forward
CGCGGATCCGCTAGC-TGCTCCGGCAGCAAAAC
BamHI-






NheI



3725
Reverse
GCCCAAGCTT-ACGCAGTTCGGAATGGAG
HindIII


530
3726
Forward
CGCGGATCCCATATG-AGTGCGAGCGCGG
BamHI-






NdeI



3727
Reverse
CCCGCTCGAG-ACGACCGACTGATTCCG
XhoI


531
3728
Forward
AAAAAAGAATTC-TATGCCGCCGCCTACCAAATCTACGG
Eco RI



3729
Reverse
AAAAAACTGCAG-TTAAAACAGCGCCGTGCCGACGACAAG
Pst I


532
3730
Forward
AAAAAAGAATTC-ATGAGCGGTCAGTTGGGCAAAGGTGC
Eco RI



3731
Reverse
AAAAAACTGCAG-TCAGTGTTCCAAGTGGTCGGTATCAAA
Pst I


532a
3732
Forward
AAAAAAGAATTC-TTGGGTGTCGCGTTTGAGCCGGAAGT
Eco RI



3733
Reverse
AAAAAACTGCAG-TCAGTGTTCCAAGTGGTCGGTATCAAA
Pst I


535
3734
Forward
AAAGAATTC-ATGCCCTTTCCCGTTTTCAGAC
Eco RI



3735
Reverse
AAACTGCAG-TCAGACGACCCCGCCTTCCCC
Pst I


537
3736
Forward
CGCGGATCCCATATG-CATACCCAAAACCAATCC
BamHI-






NdeI



3737
Reverse
CCCGCTCGAG-ATCCTGCAAATAAAGGGTT
XhoI


538
3738
Forward
CGCGGATCCCATATG-GTCGAGCTGGTCAAAGC
BamHI-






NdeI



3739
Reverse
CCCGCTCGAG-TGGCATTTCGGTTTCGTC
XhoI


539
3740
Forward
CGCGGATCCGCTAGC-GAGGATTTGCAGGAAA
BamHI-






NheI



3741
Reverse
CCCGCTCGAG-TACCAATGTCGGCAAATC
XhoI


542
3742
Forward
AAAGAATTC-ATGCCGTCTGAAACCGTGTC
Eco RI



3743
Reverse
AAACTGCAG-TTACCGCGAACCGGTCAGGAT
Pst I


543
3744
Forward
AAAAAAGAATTC-GCCTTCGATGGCGACGTTGTAGGTAC
Eco RI



3745
Reverse
AAAAAATCTAGA-
Xba I





TTAATGAAGAAGAACATATTGGAATTTTGG



543a
3746
Forward
AAAAAAGAATTC-GGCAAAACTCGTCATGAATTTGC
Eco RI



3747
Reverse
AAAAAATCTAGA-
Xba I





TTAATGAAGAAGAACATATTGGAATTTTGG



544
3748
Forward
AAAGAATTC-GCGCCCGCCTTCTCCCTGCCCGACCTGCACGG
Eco RI



3749
Reverse
AAACTGCAG-CTATTGCGCCACGCGCGTATCGAT
Pst I


544a
3750
Forward
AAAAAAGAATTC-
Eco RI





GCAAATGACTATAAAAACAAAAACTTCCAAGTACTTGC




3751
Reverse
AAACTGCAG-CTATTGCGCCACGCGCGTATCGAT
Pst I


547
3752
Forward
AAAGAATTC-ATGTTCGTAGATAACGGATTTAATAAAAC
Eco RI



3753
Reverse
AAACTGCAG-TTAACAACAAAAAACAAACCGCTT
Pst I


548
3754
Forward
AAAGAATTC-GCCTGCAAACCTCAAGACAACAGTGCGGC
Eco RI



3755
Reverse
AAACTGCAG-TCAGAGCAGGGTCCTTACATCGGC
Pst I


550
3756
Forward
AAAAAAGTCGAC-
Sal I





ATGATAACGGACAGGTTTCATCTCTTTCATTTTCC




3757
Reverse
AAACTGCAG-TTACGCAAACGCTGCAAAATCCCC
Pst I


550a
3758
Forward
AAAAAAGAATTC-GTAAATCACGCCTTTGGAGTCGCAAACGG
Eco RI



3759
Reverse
AAACTGCAG-TTACGCAAACGCTGCAAAATCCCC
Pst I


552
3760
Forward
AAAAAAGAATTC-TTGGCGCGTTGGCTGGATAC
Eco RI



3761
Reverse
AAACTGCAG-TTATTTCTGATGCCTTTTCCCAAC
Pst I


554
3762
Forward
CGCGGATCCCATATG-TCGCCCGCGCCCAAC
BamHI-






NdeI



3763
Reverse
CCCGCTCGAG-CTGCCCTGTCAGACAC
XhoI


556
3764
Forward
AAAGAATTC-GCGGGCGGTTTTGTTTGGACATCCCG
Eco RI



3765
Reverse
AAACTGCAG-TTAACGGTGCGGACGTTTCTGACC
Pst I


557
3766
Forward
CGCGGATCCCATATG-TGCGGTTTCCACCTGAA
BamHI-






NdeI



3767
Reverse
CCCGCTCGAG-TTCCGCCTTCAGAAAGG
XhoI


558
3768
Forward
AAAGAATTC-GAGCTTTATATGTTTCAACAGGGGACGGC
Eco RI



3769
Reverse
AAACTGCAG-CTAAACAATGCCGTCTGAAAGTGGAGA
Pst I


558a
3770
Forward
AAAAAAGAATTC-ATTAGATTCTATCGCCATAAACAGACGGG
Eco RI



3771
Reverse
AAAAAACTGCAG-CTAAACAATGCCGTCTGAAAGTGGAGA
Pst I


560
3772
Forward
AAAAAAGAATTC-
Eco RI





TCGCCTTTCCGGGACGGGGCGCACAAGATGGC




3773
Reverse
AAAAAACTGCAG-TCATGCGGTTTCAGACGGCATTTTGGC
Pst I


561
3774
Forward
CCGGAATTCTACATATG-ATACTGCCAGCCCGT
EcoRI-






NdeI



3775
Reverse
CCCGCTCGAG-TTTCAAGCTTTCTTCAGATG
XhoI


562
3776
Forward
CGCGGATCCCATATG-GCAAGCCCGTCGAG
BamHI-






NdeI



3777
Reverse
CCCGCTCGAG-AGACCAACTCCAACTCGT
XhoI


565
3778
Forward
CGCGGATCCCATATG-AAGTCGAGCGCGAAATAC
BamHI-






NdeI



3779
Reverse
CCCGCTCGAG-GGCATTGATCGGCGGC
XhoI


566
3780
Forward
CGCGGATCCCATATG-GTCGGTGGCGAAGAGG
BamHI-






NdeI



3781
Reverse
CCCGCTCGAG-CGCATGGGCGAAGTCA
XhoI


567
3782
Forward
CCGGAATTCTACATATG-AGTGCGAACATCCTTG
EcoRI-






NdeI



3783
Reverse
CCCGCTCGAG-TTTCCCCGACACCCTCG
XhoI


568
3784
Forward
CGCGGATCCCATATG-CTCAGGGTCAGACC
BamHI-






NdeI



3785
Reverse
CCCGCTCGAG-CGGCGCGGCGTTCAG
XhoI


569
3786
Forward
AAAAAAGAATTC-CTGATTGCCTTGTGGGAATATGCCCG
Eco RI



3787
Reverse
AAAAAACTGCAG-TTATGCATAGACGCTGATAACGGCAAT
Pst I


570
3788
Forward
CGCGGATCCCATATG-GACACCTTCCAAAAAATCG
BamHI-






NdeI



3789
Reverse
CCCGCTCGAG-GCGGGCGTTCATTTCTTT
XhoI


571
3790
Forward
AAAAAAGAATTC-
Eco RI





ATGGGTATTGCCGGCGCCGTAAATGTTTTGAACCC




3791
Reverse
AAAAAACTGCAG-TTATGGCCGACGCGCGGCTACCTGACG
Pst I


572
3792
Forward
CGCGGATCCCATATG-GCGCAAAAAGGCAAAACC
BamHI-






NdeI



3793
Reverse
CCCGCTCGAG-GCGCAGTGTGCCGATA
XhoI


573
3794
Forward
CGCGGATCCCATATG-CCCTGTTTGTGCCG
BamHI-






NdeI



3795
Reverse
CCCGCTCGAG-GACGGTGTCATTTCGCC
XhoI


574
3796
Forward
CGCGGATCCCATATG-TGGTTTGCCGCCCGC
BamHI-






NdeI



3797
Reverse
CCCGCTCGAG-AACTTCGATTTTATTCGGG
XhoI


575
3798
Forward
CGCGGATCCCATATG-GTTTCGGGCGAGG
BamHI-






NdeI



3799
Reverse
CCCGCTCGAG-CATTCCGAATCTGAACAG
XhoI


576
3800
Forward
CGCGGATCCCATATG-GCCGCCCCCGCATCT
BamHI-






NdeI



3801
Reverse
CCCGCTCGAG-ATTTACTTTTTTGATGTCGAC
XhoI


577
3802
Forward
CGCGGATCCCATATG-GAAAGGAACGGTGTATTT
BamHI-






NdeI



3803
Reverse
CCCGCTCGAG-AGGCTGTTTGGTAGATTCG
XhoI


578
3804
Forward
CGCGGATCCCATATG-AGAAGGTTCGTACAG
BamHI-






NdeI



3805
Reverse
CCCGCTCGAG-GCCAACGCCTCCACG
XhoI


579
3806
Forward
CGCGGATCCCATATG-AGATTGGGCGTTTCCAC
BamHI-






NdeI



3807
Reverse
CCCGCTCGAG-AGAATTGATGATGTGTATGT
XhoI


580
3808
Forward
CGCGGATCCCATATG-AGGCAGACTTCGCCGA
BamHI-






NdeI



3809
Reverse
CCCGCTCGAG-CACTTCCCCCGAAGTG
XhoI


581
3810
Forward
CGCGGATCCCATATG-CACTTCGCCCAGC
BamHI-






NdeI



3811
Reverse
CCCGCTCGAG-CGCCGTTTGGCTTTGG
XhoI


582
3812
Forward
AAAAAAGAATTC-TTTGGAGAGACCGCGCTGCAATGCGC
Eco RI



3813
Reverse
AAAAAATCTAGA-TCAGATGCCGTCCCAGTCGTTGAA
Xba I


583
3814
Forward
AAAAAAGAATTC-ACTGCCGGCAATCGACTGCATAATCG
Eco RI



3815
Reverse
AAAAAACTGCAG-TTAACGGAGGTCAATATGATGAAATTG
Pst I


584
3816
Forward
AAAAAAGAATTC-
Eco RI





GCGGCTGAAGCATTGAATTACAATATTGTC




3817
Reverse
AAAAAACTGCAG-TCAGAACTGAACCGTCCCATTGACGCT
Pst I


585
3818
Forward
AAAAAAGGTACC-TCTTTCTGGCTGGTGCAGAACACCCTTGC
Eco RI



3819
Reverse
AAAAAACTGCAG-TCAGTTCGCACTTTTTTCTGTTTTGGA
Pst I


586
3820
Forward
CGCGGATCCCATATG-GCAGCCCATCTCG
BamHI-






NdeI



3821
Reverse
CCCGCTCGAG-TTTCAGCGAATCAAGTTTC
XhoI


587
3822
Forward
CGCGGATCCCATATG-GACCTGCCCTTGACGA
BamHI-






NdeI



3823
Reverse
CCCGCTCGAG-AAATGTATGCTGTACGCC
XhoI


588
3824
Forward
AAAAAAGAATTC-GCCGTCCTGACTTCCTATCAAGAACCAGG
Eco RI



3825
Reverse
AAAAAACTGCAG-TTATTTGTTTTTGGGCAGTTTCACTTC
Pst I


589
3826
Forward
AAAAAAGAATTC-
Eco RI





ATGCAACAAAAAATCCGTTTCCAAATCGAAGG




3827
Reverse
AAAAAACTGCAG-CTAATCGATTTTTACCCGTTTCAGGCG
Pst I


590
3828
Forward
AAAAAAGAATTC-ATGAAAAAACCTTTGATTTCAGTTGCGGC
Eco RI



3829
Reverse
AAAAAACTGCAG-TTACTGCTGCGGCTCTGAAACCAT
Pst I


591
3830
Forward
AAAAAAGAATTC-CACTACATCGTTGCCAGATTGTGCGG
Eco RI



3831
Reverse
AAAAAACTGCAG-CTAACCGAGCAGCCGGGTAACGTCGTT
Pst I


592a
3832
Forward
AAAAAAGAATTC-CGCGATTACACCGCCAAGCTGAAAATGGG
Eco RI



3833
Reverse
AAAAAACTGCAG-TTACCAAACGTCGGATTTGATACG
Pst I


593
3834
Forward
CGCGGATCCGCTAGC-CTTGAACTGAACGGACTC
BamHI-






NheI



3835
Reverse
CCCGCTCGAG-GCGGAAGCGGACGATT
XhoI


594a
3836
Forward
AAAAAAGAATTC-GGTAAGTTCGCCGTTCAGGCCTTTCA
Eco RI



3837
Reverse
AAAAAACTGCAG-TTACGCCGCCGTTTCCTGACACTCGCG
Pst I


595
3838
Forward
AAAAAAGAATTC-TGCCAGCCGCCGGAGGCGGAGAAAGC
Eco RI



3839
Reverse
AAAAAACTGCAG-TTATTTCAAGCCGAGTATGCCGCG
Pst I


596
3840
Forward
CGCGGATCCCATATG-TCCCAACAATACGTC
BamHI-






NdeI



3841
Reverse
CCCGCTCGAG-ACGCGTTACCGGTTTGT
XhoI


597
3842
Forward
CGCGGATCCCATATG-CTGCTTCATGTCAGC
BamHI-






NdeI



3843
Reverse
GCCCAAGCTT-ACGTATCCAGCTCGAAG
HindIII


601
3844
Forward
CGCGGATCCCATATG-ATATGTTCCCAACCGGCAAT
BamHI-






NdeI



3845
Reverse
CCCGCTCGAG-AAAACAATCCTCAGGCAC
XhoI


602
3846
Forward
CGCGGATCCGCTAGC-TTGCTCCATCAATGC
BamHI-






NheI



3847
Reverse
CCCGCTCGAG-ATGCAGCTGCTAAAAGCG
XhoI


603
3848
Forward
AAAAAAGAATTC-CTGTCCTCGCGTAGGCGGGGACGGGG
Eco RI



3849
Reverse
AAAAAACTGCAG-CTACAAGATGCCGGCAAGTTCGGC
Pst I


604
3850
Forward
CGCGGATCCGCTAGC-CCCGAAGCGCACTT
BamHI-






NheI



3851
Reverse
CCCGCTCGAG-GACGGCATCTGCACGG
XhoI


606a
3852
Forward
AAAAAAGAATTC-CGCGAATACCGCGCCGATGCGGGCGC
Eco RI



3853
Reverse
AAAAAACTGCAG-TTAAAGCGATTTGAGGCGGGCGATACG
Pst I


607
3854
Forward
AAAAAAGAATTC-ATGCTGCTCGACCTCAACCGCTTTTC
Eco RI



3855
Reverse
AAAAAACTGCAG-TCAGACGGCCTTATGCGATCTGAC
Pst I


608
3856
Forward
AAAAAAGAATTC-ATGTCCGCCCTCCTCCCCATCATCAACCG
Eco RI



3857
Reverse
AAAAAACTGCAG-TTAGTCTATCCAAATGTCGCGTTC
Pst I


609
3858
Forward
CGCGGATCCCATATG-GTTGTGGATAGACTCG
BamHI-






NdeI



3859
Reverse
CCCGCTCGAG-CTGGATTATGATGTCTGTC
XhoI


610
3860
Forward
CGCGGATCCCATATG-ATTGGAGGGCTTATGCA
BamHI-






NdeI



3861
Reverse
CCCGCTCGAG-ACGCTTCAACATCTTTGCC
XhoI


611
3862
Forward
CGCGGATCCCATATG-CCGTCTCAAAACGGG
BamHI-






NdeI



3863
Reverse
CCCGCTCGAG-AACGACTTTGAACGCGCAA
XhoI


613
3864
Forward
CGCGGATCCCATATG-TCGCGTTCGAGCCG3
BamHI-






NdeI



3865
Reverse
CCCGCTCGAG-AGCCTGTAAAATAAGCGGC
XhoI


614
3866
Forward
CGCGGATCCCATATG-TCCGTCGTGAGCGGC
BamHI-






NdeI



3867
Reverse
CCCGCTCGAG-CCATACTGCGGCGTTC
XhoI


616
3868
Forward
AAAAAAGAATTC-ATGTCAAACACAATCAAAATGGTTGTCGG
Eco RI



3869
Reverse
AAAAAATCTAGA-TTAGTCCGGGCGGCAGGCAGCTCG
Xba I


619a
3870
Forward
AAAAAAGAATTC-GGGCTTCTCGCCGCCTCGCTTGC
Eco RI



3871
Reverse
AAAAAACTGCAG-TCATTTTTTGTGTTTTAAAACGAGATA
Pst I


622
3872
Forward
CGCGGATCCCATATG-GCCGCCCTGCCTAAAG
BamHI-






NdeI



3873
Reverse
CCCGCTCGAG-TTTGTCCAAATGATAAATCTG
XhoI


624
3874
Forward
CGCGGATCCCATATG-TCCCCGCGCTTTTACCG
BamHI-






NdeI



3875
Reverse
CCCGCTCGAG-AGATTCGGGCCTGCGC
XhoI


625
3876
Forward
CGCGGATCCCATATG-TTTGCAACCAGGAAAATG
BamHI-






NdeI



3877
Reverse
CCCGCTCGAG-CGGCAAAATTACCGCCTT
XhoI


627a
3878
Forward
AAAAAAGAATTC-AAAGCAGGCGAGGCAGGCGCGCTGGG
Eco RI



3879
Reverse
AAAAAACTGCAG-
Pst I





TTACGAATGAAACAGGGTACCCGTCATCAAGGC



628
3880
Forward
AAAAAAGGTACC-GCCTTACAAACATGGATTTTGCGTTC
Kpn I



3881
Reverse
AAAAAACTGCAG-CTACGCACCTGAAGCGCTGGCAAA
Pst I


629a
3882
Forward
AAAAAAGAATTC-GCCACCTTTATCGCGTATGAAAACGA
Eco RI



3883
Reverse
AAAAAACTGCAG-TTACAACACCGCCGTCCGGTTCAAACC
Pst I


630a
3884
Forward
AAAAAAGAATTC-GCGGCTTTGGGTATTTCTTTCGG
Eco RI



3885
Reverse
AAAAAACTGCAG-TTAGGAGACTTCGCCAATGGAGCCGGG
Pst I


635
3886
Forward
AAAAAAGAATTC-
Eco RI





ATGACCCAGCGACGGGTCGGCAAGCAAAACCG




3887
Reverse
AAAAAACTGCAG-TTAATCCACTATAATCCTGTTGCT
Pst I


638
3888
Forward
AAAAAAGAATTC-ATGATTGGCGAAAAGTTTATCGTAGTTGG
Eco RI



3889
Reverse
AAAAAACTGCAG-TCACGAACCGATTATGCTGATCGG
Pst I


639
3890
Forward
CGCGGATCCCATATG-ATGCTTTATTTTGTTCG
BamHI-






NdeI



3891
Reverse
CCCGCTCGAG-ATCGCGGCTGCCGAC
XhoI


642
3892
Forward
CGCGGATCCCATATG-CGGTATCCGCCGCAAT
BamHI-






NdeI



3893
Reverse
CCCGCTCGAG-AGGATTGCGGGGCATTA
XhoI


643
3894
Forward
CGCGGATCCCATATG-GCTTCGCCGTCGGCAG
BamHI-






NdeI



3895
Reverse
CCCGCTCGAG-AACCGAAAAACAGACCGC
XhoI


644
3896
Forward
AAAAAAGAATTC-
Eco RI





ATGCCGTCTGAAAGGTCGGCGGATTGTTGCCC




3897
Reverse
AAAAAATCTAGA-CTACCCGCAATATCGGCAGTCCAATAT
Pst I


645
3898
Forward
AAAAAAGAATTC-GTGGAACAGAGCAACACGTTAAATCG
Eco RI



3899
Reverse
AAAAAACTGCAG-CTACGAGGAAACCGAAGACCAGGCCGC
Pst I


647
3900
Forward
AAAAAAGAATTC-ATGCAAAGGCTCGCCGCAGACGG
Eco RI



3901
Reverse
AAAAAACTGCAG-TTAGATTATCAGGGATATCCGGTAGAA
Pst I


648
3902
Forward
AAAAAAGAATTC-
Eco RI





ATGAACAGGCGCGACGCGCGGATCGAACG




3903
Reverse
AAAAAACTGCAG-TCAAGCTGTGTGCTGATTGAATGCGAC
Pst I


649
3904
Forward
AAAAAAGAATTC-GGTACGTCAGAACCCGCCCACCG
Eco RI



3905
Reverse
AAAAAACTGCAG-TTAACGGCGGAAACTGCCGCCGTC
Pst I


650
3906
Forward
AAAAAAGAATTC-ATGTCCAAACTCAAAACCATCGC
Eco RI



3907
Reverse
AAAAAACTGCAG-TCAGACGGCATGGCGGTCTGTTTT
Pst I


652
3908
Forward
AAAAAAGGTACC-
Kpn I





GCTGCCGAAGACTCAGGCCTGCCGCTTTACCG




3909
Reverse
AAAAAACTGCAG-TTATTTGCCCAGTTGGTAGAATGCGGC
Pst I


653
3910
Forward
AAAAAAGAATTC-GCGGCTTTGCCGGTAATTTTCATCGG
Eco RI



3911
Reverse
AAAAAACTGCAG-CTATGCCGGTCTGGTTGCCGGCGGCGA
Pst I


656a
3912
Forward
AAAAAAGAATTC-CGGCCGACGTCGTTGCGTCCTAAGTC
Eco RI



3913
Reverse
AAAAAACTGCAG-CTACGATTTCGGCGATTTCCACATCGT
Pst I


657
3914
Forward
AAAAAAGAATTC-GCAGAATTTGCCGACCGCCATTTGTGCGC
Eco RI



3915
Reverse
AAAAAACTGCAG-TTATAGGGACTGATGCAGTTTTTTTGC
Pst I


658
3916
Forward
CGCGGATCCCATATG-GTGTCCGGAATTGTG
BamHI-






NdeI



3917
Reverse
CCCGCTCGAG-GGCAGAATGTTTACCGTT
XhoI


661
3918
Forward
AAAAAAGAATTC-
Eco RI





ATGCACATCGGCGGCTATTTTATCGACAACCC




3919
Reverse
AAAAAACTGCAG-TCACGACGTGTCTGTTCGCCGTCGGGC
Pst I


663
3920
Forward
CGCGGATCCCATATG-TGTATCGAGATGAAATT
BamHI-






NdeI



3921
Reverse
CCCGCTCGAG-GTAAAAATCGGGGCTGC
XhoI


664
3922
Forward
CGCGGATCCCATATG-GCGGCTGGCGCGGT
BamHI-






NdeI



3923
Reverse
CCCGCTCGAG-AAATCGAGTTTTACACCAC
XhoI


665
3924
Forward
AAAAAAGAATTC-ATGAAATGGGACGAAACGCGCTTCGG
Eco RI



3925
Reverse
AAAAAACTGCAG-TCAATCCAAAATTTTGCCGACGATTTC
Pst I


666
3926
Forward
AAAAAAGAATTC-AACTCAGGCGAAGGAGTGCTTGTGGC
Eco RI



3927
Reverse
AAAAAATCTAGA-TCAGTTTAGGGATAGCAGGCGTAC
Xba I


667
3928
Forward
AAAAAAGAATTC-
Eco RI





CCGCATCCGTTTGATTTCCATTTCGTATTCGTCCG




3929
Reverse
AAAAAACTGCAG-TTAATGACACAATAGGCGCAAGTC
Pst I


669
3930
Forward
AAAAAAGAATTC-ATGCGCCGCATCATTAAAAAACACCAGCC
Eco RI



3931
Reverse
AAAAAACTGCAG-TTACAGTATCCGTTTGATGTCGGC
Pst I


670a
3932
Forward
AAAAAAGAATTC-AAAAACGCTTCGGGCGTTTCGTCTTC
Eco RI



3933
Reverse
AAAAAACTGCAG-
Pst I





TTAGGAGCTTTTGGAACGCGTCGGACTGGC



671
3934
Forward
CGCGGATCCCATATG-ACCAGCAGGGTAAC
BamHI-






NdeI



3935
Reverse
CCCGCTCGAG-AGCAACTATAAAAACGCAAG
XhoI


672
3936
Forward
CGCGGATCCCATATG-AGGAAAATCCGCACC
BamHI-






NdeI



3937
Reverse
CCCGCTCGAG-ACGGGATAGGCGGTTG
XhoI


673
3938
Forward
AAAAAAGAATTC-ATGGATATTGAAACCTTCCTTGCAGG
Eco RI



3939
Reverse
AAAAAACTGCAG-CTACAAACCCAGCTCGCGCAGGAA
Pst I


674
3940
Forward
AAAAAAGAATTC-ATGAAAACAGCCCGCCGCCGTTCCCG
Eco RI



3941
Reverse
AAAAAACTGCAG-TCAACGGCGTTTGGGCTCGTCGGG
Pst I


675
3942
Forward
CGCGGATCCCATATG-AACACCATCGCCCC
BamHI-






NdeI



3943
Reverse
CCCGCTCGAG-TTCTTCGTCTTCAAACTGT
XhoI


677a
3944
Forward
AAAAAAGAATTC-AGACGGCATTCCCGATCAGTCGATTTTGA
Eco RI



3945
Reverse
AAAAAACTGCAG-TTACGTATGCGCGAAATCGACCGCCGC
Pst I


680
3946
Forward
CGCGGATCCGCTAGC-ACGAAGGGCAGTTCGG
BamHI-






NheI



3947
Reverse
CCCGCTCGAG-CATCAAAAACCTGCCGC
XhoI


681
3948
Forward
AAAAAAGAATTC-ATGACGACGCCGATGGCAATCAGTGC
Eco RI



3949
Reverse
AAAAAACTGCAG-TTACCGTCTTCCGCAAAAAACAGC
Pst I


683
3950
Forward
CGCGGATCCCATATG-TGCAGCACACCGGACAA
BamHI-






NdeI



3951
Reverse
CCCGCTCGAG-GAGTTTTTTTCCGCATACG
XhoI


684
3952
Forward
CGCGGATCCCATATG-TGCGGTACTGTGCAAAG
BamHI-






NdeI



3953
Reverse
CCCGCTCGAG-CTCGACCATCTGTTGCG
XhoI


685
3954
Forward
CGCGGATCCCATATG-TGTTTGCTTAATAATAAACATT
BamHI-






NdeI



3955
Reverse
CCCGCTCGAG-CTTTTTCCCCGCCGCA
XhoI


686
3956
Forward
CGCGGATCCCATATG-TGCGGCGGTTCGGAAG
BamHI-






NdeI



3957
Reverse
CCCGCTCGAG-CATTCCGATTCTGATGAAG
XhoI


687
3958
Forward
CGCGGATCCCATATG-TGCGACAGCAAAGTCCA
BamHI-






NdeI



3959
Reverse
CCCGCTCGAG-CTGCGCGGCTTTTTGTT
XhoI


690
3960
Forward
CGCGGATCCCATATG-TGTTCTCCGAGCAAAGAC
BamHI-






NdeI



3961
Reverse
CCCGCTCGAG-TATTCGCCCCGTGTTTGG
XhoI


691
3962
Forward
CGCGGATCCCATATG-GCCACGGCTTATATCCC
BamHI-






NdeI



3963
Reverse
CCCGCTCGAG-TTTGAGGCAGGAAGAAAG
XhoI


694
3964
Forward
CGCGGATCCCATATG-TTGGTTTCCGCATCCGG
BamHI-






NdeI



3965
Reverse
CCCGCTCGAG-TCTGCGTCGGTGCGGT
XhoI


695
3966
Forward
CGCGGATCCCATATG-TTGCCTCAAACTCGTCCG
BamHI-






NdeI



3967
Reverse
CCCGCTCGAG-TCGTTTGCGCACGGCT
XhoI


696
3968
Forward
CGCGGATCCCATATG-TTGGGTTGCCGGCAGG
BamHI-






NdeI



3969
Reverse
CCCGCTCGAG-TTGATTGCCGCAATGATG
XhoI


700a
3970
Forward
AAAAAAGAATTC-GCATCGACAGACGGTGTGTCGTGGAC
Eco RI



3971
Reverse
AAAAAACTGCAG-TTACGCTACCGGCACGACTTCCAAACC
Pst I


701
3972
Forward
CGCGGATCCCATATG-AAGACTTGTTTGGATACTTC
BamHI-






NdeI



3973
Reverse
CCCGCTCGAG-TGCCGACAACAGCCTC
XhoI


702
3974
Forward
AAAAAAGAATTC-ATGCCGTGTTCCAAAGCCAGTTGGATTTC
Eco RI



3975
Reverse
AAAAAACTGCAG-TTAACCCCATTCCACCCGGAGAACCGA
Pst I


703
3976
Forward
CGCGGATCCGCTAGC-CAAACGCTGGCAACCG
BamHI-






NheI



3977
Reverse
CCCGCTCGAG-TTTTGCAGGTTTGATGTTTG
XhoI


704a
3978
Forward
AAAAAAGAATTC-GCTTCTACCGGTACGCTGGCGCG
Eco RI



3979
Reverse
AAAAAACTGCAG-
Pst I





TTAGTTTTGCCGGATAATATGGCGGGTGCG



707
3980
Forward
CGCGGATCCGCTAGC-GAAATTATTAACGATGCAGA
BamHI-






NheI



3981
Reverse
CCCGCTCGAG-GAAACTGTAATTCAAGTTGA
XhoI


708
3982
Forward
CGCGGATCCGCTAGC-CCTTTTAAGCCATCCAAAA
BamHI-






NheI



3983
Reverse
CCCGCTCGAG-TTGACCGGTGAGGACG
XhoI


710
3984
Forward
CGCGGATCCCATATG-GAAACCCACGAAAAAATC
BamHI-






NdeI



3985
Reverse
CCCGCTCGAG-AACGGTTTCGGTCAG
XhoI


714
3986
Forward
CGCGGATCCCATATG-AGCTATCAAGACATCTT
BamHI-






NdeI



3987
Reverse
CCCGCTCGAG-GCGGTAGGTAAATCGGAT
XhoI


716
3988
Forward
CGCGGATCCCATATG-GCCAACAAACCGGCAAG
BamHI-






NdeI



3989
Reverse
CCCGCTCGAG-TTTAGAACCGCATTTGCC
XhoI


718
3990
Forward
CGCGGATCCCATATG-GAGCCGATAATGGCAAA
BamHI-






NdeI



3991
Reverse
CCCGCTCGAG-GGCGCGGGCATGGTCTTGTCC
XhoI


720
3992
Forward
CGCGGATCCCATATG-AGCGGATGGCATACC
BamHI-






NdeI



3993
Reverse
CCCGCTCGAG-TTTTGCATAGCTGTTGACCA
XhoI


723
3994
Forward
CGCGGATCCCATATG-CGACCCAAGCCCC
BamHI-






NdeI



3995
Reverse
CCCGCTCGAG-AATGCGAATCCGCCGCC
XhoI


725
3996
Forward
CGCGGATCCCATATG-GTGCGCACGGTTAAA
BamHI-






NdeI



3997
Reverse
CCCGCTCGAG-TTGCTTATCCTTAAGGGTTA
XhoI


726
3998
Forward
CGCGGATCCCATATG-ACCATCTATTTCAAAAAC
BamHI-






NdeI



3999
Reverse
CCCGCTCGAG-GCCGATGTTTAGCGTCC
XhoI


728
4000
Forward
CGCGGATCCCATATG-TTTTGGCTGGGAACGGG
BamHI-






NdeI



4001
Reverse
CCCGCTCGAG-GTGAGAAAGGTCGCGC
XhoI


729
4002
Forward
CGCGGATCCCATATG-TGCACCATGATTCCCCA
BamHI-






NdeI



4003
Reverse
GCCCAAGCTT-TTTGTCGGTTTGGGTATC
HindIII


731
4004
Forward
CGCGGATCCGCTAGC-GCCGTGCCGGAGG
BamHI-






NheI



4005
Reverse
CCCGCTCGAG-ACGGGCGCGGCAG
XhoI


732
4006
Forward
CCGGAATTCTACATATG-TCGAAACCTGTTTTTAAGAA
EcoRI-






NdeI



4007
Reverse
CCCGCTCGAG-CTTCTTATCTTTTTTATCTTTC
XhoI


733
4008
Forward
CGCGGATCCCATATG-GCCTGCGGCGGCAA
BamHI-






NdeI



4009
Reverse
CCCGCTCGAG-TCGCTTGCCTCCTTTAC
XhoI


734
4010
Forward
CGCGGATCCCATATG-GCCGATACTTACGGCTAT
BamHI-






NdeI



4011
Reverse
CCCGCTCGAG-TTTGAGATTTTGAATCAAAGAG
XhoI


735
4012
Forward
CGCGGATCCCATATG-AAGCAGCAGGCGGTCA
BamHI-






NdeI



4013
Reverse
CCCGCTCGAG-ATTTCCGTAGCCGAGGG
XhoI


737
4014
Forward
CGCGGATCCCATATG-CACCACGACGGACACG
BamHI-






NdeI



4015
Reverse
CCCGCTCGAG-GTCGTCGCGGCGGGA
XhoI


739
4016
Forward
CGCGGATCCCATATG-GCAAAAAAACCGAACA
BamHI-






NdeI



4017
Reverse
CCCGCTCGAG-GAAGAGTTTGTCGAGAATT
XhoI


740
4018
Forward
CGCGGATCCCATATG-GCCAATCCGCCCGAAG
BamHI-






NdeI



4019
Reverse
CCCGCTCGAG-AAACGCGCCAAAATAGTG
XhoI


741
4020
Forward
CGCGGATCCCATATG-TGCAGCAGCGGAGGG
BamHI-






NdeI



4021
Reverse
CCCGCTCGAG-TTGCTTGGCGGCAAGGC
XhoI


743
4022
Forward
CGCGGATCCCATATG-GACGGTGTTGTGCCTGTT
BamHI-






NdeI



4023
Reverse
CCCGCTCGAG-CTTACGGATCAAATTGACG
XhoI


745
4024
Forward
CGCGGATCCCATATG-TTTTGGCAACTGACCG
BamHI-






NdeI



4025
Reverse
CCCGCTCGAG-CAAATCAGATGCCTTTAGG
XhoI


746
4026
Forward
CGCGGATCCCATATG-TCCGAAAACAAACAAAAC
BamHI-






NdeI



4027
Reverse
CCCGCTCGAG-TTCATTCGTTACCTGACC
XhoI


747
4028
Forward
CCGGAATTCTAGCTAGC-CTGACCCCTTGGG
EcoRI-






NheI



4029
Reverse
GCCCAAGCTT-TTTTGATTTTAATTGACTATAGAAC
HindIII


749
4030
Forward
CGCGGATCCCATATG-TGCCAGCCGCCG
BamHI-






NdeI



4031
Reverse
CCCGCTCGAG-TTTCAAGCCGAGTATGC
XhoI


750
4032
Forward
CGCGGATCCCATATG-TGTTCGCCCGAACCTG
BamHI-






NdeI



4033
Reverse
CCCGCTCGAG-CTTTTTCCCCGCCGCAA
XhoI


758
4034
Forward
CGCGGATCCCATATG-AACAATCTGACCGTGTT
BamHI-






NdeI



4035
Reverse
CCCGCTCGAG-TGGCTCAATCCTTTCTGC
XhoI


759
4036
Forward
CGCGGATCCGCTAGC-CGCTTCACACACACCAC
BamHI-






NheI



4037
Reverse
CCCGCTCGAG-CCAGTTGTAGCCTATTTTG
XhoI


763
4038
Forward
CGCGGATCCCATATG-CTGCCTGAAGCATGGCG
BamHI-






NdeI



4039
Reverse
CCCGCTCGAG-TTCCGCAAATACCGTTTCC
XhoI


764
4040
Forward
CGCGGATCCCATATG-TTTTTCTCCGCCCTGA
BamHI-






NdeI



4041
Reverse
CCCGCTCGAG-TCGCTCCCTAAAGCTTTC
XhoI


765
4042
Forward
CGCGGATCCCATATG-TTAAGATGCCGTCCG
BamHI-






NdeI



4043
Reverse
CCCGCTCGAG-ACGCCGACGTTTTTTATTAA
XhoI


767
4044
Forward
CGCGGATCCCATATG-CTGACGGAAGGGGAAG
BamHI-






NdeI



4045
Reverse
CCCGCTCGAG-TTTCTGTACAGCAGGGG
XhoI


768
4046
Forward
CGCGGATCCCATATG-GCCCCGCAAAAACCCG
BamHI-






NdeI



4047
Reverse
CCCGCTCGAG-TTTCATCCCTTTTTTGAGC
XhoI


770
4048
Forward
CGCGGATCCCATATG-TGCGGCAGCGGCGAA
BamHI-






NdeI



4049
Reverse
CCCGCTCGAG-GCGTTTGTCGAGATTTTC
XhoI


771
4050
Forward
CGCGGATCCCATATG-TCCGTATATCGCACCTTC
BamHI-






NdeI



4051
Reverse
CCCGCTCGAG-CGGTTCTTTAGGTTTGAG
XhoI


772
4052
Forward
CGCGGATCCCATATG-TTTGCGGCGTTGGTGG
BamHI-






NdeI



4053
Reverse
CCCGCTCGAG-CAATGCCGACATCAAACG
XhoI


774
4054
Forward
CGCGGATCCCATATG-TCCGTTTCACCCGTTCC
BamHI-






NdeI



4055
Reverse
CCCGCTCGAG-TCGTTTGCGCACGGCT
XhoI


790
4056
Forward
CGCGGATCCCATATG-GCAAGAAGGTCAAAAAC
BamHI-






NdeI



4057
Reverse
CCCGCTCGAG-GGCGTTGTTCGGATTTCG
XhoI


900
4058
Forward
CGCGGATCCCATATG-CCGTCTGAAATGCCG
BamHI-






NdeI



4059
Reverse
CCCGCTCGAG-ATATGGAAAAGTCTGTTGTC
XhoI


901
4060
Forward
CGCGGATCCCATATG-CCCGATTTTTCGATG
BamHI-






NdeI



4061
Reverse
CCCGCTCGAG-AAAATGGAACAATACCAGG
XhoI


902
4062
Forward.2
CCGGAATTCTACATATG-TTGCACTTTCAAAGGATAATC
EcoRI-






NdeI



4063
Reverse
CCCGCTCGAG-AAAAATGTACAATGGCGTAC
XhoI


903
4064
Forward
CCGGAATTCTAGCTAGC-CAGCGTCAGCAGCACAT
EcoRI-






NheI



4065
Reverse
CCCGCTCGAG-GAAACTGTAATTCAAGTTGAA
XhoI


904
4066
Forward
AAAAAAGGTACC-ATGATGCAGCACAATCGTTTC
Kpn I



4067
Reverse
AAACTGCAG-TTAATATCGATAGGTTATATG
Pst I


904a
4068
Forward
AAAAAAGAATTC-CGGCTCGGCATTGTGCAGATGTTGCA
Eco RI



4069
Reverse
AAACTGCAG-TTAATATCGATAGGTTATATG
Pst I


905
4070
Forward
CGCGGATCCCATATG-AACAAAATATACCGCATC
BamHI-






NdeI



4071
Reverse
CCCGCTCGAG-CCACTGATAACCGACAGAT
XhoI


907
4072
Forward
CGCGGATCCCATATG-GGCGCGCAACGTGAG
BamHI-






NdeI



4073
Reverse
CCCGCTCGAG-ACGCCACTGCCAGCG
XhoI


908
4074
Forward
AAAGAATTC-GCAGAGTTAGTAGGCGTTAATAAAAATAC
Eco RI



4075
Reverse
AAACTGCAG-TTAATATGGTTTTGTCGTTCG
Pst I


909
4076
Forward
CGCGGATCCCATATG-TGCGCGTGGGAAACTTAT
BamHI-






NdeI



4077
Reverse
CCCGCTCGAG-TCGGTTTTGAAACTTTGGTTTT
XhoI


910
4078
Forward
AAAGAATTC-GCATTTGCCGGCGACTCTGCCGAGCG
Eco RI



4079
Reverse
AAACTGCAG-TCAGCGATCGAGCTGCTCTTT
Pst I


911
4080
Forward
AAAGAATTC-GCTTTCCGCGTGGCCGGCGGTGC
Eco RI



4081
Reverse
AAAAAACTGCAG-GTCGACTTATTCGGCGGCTTTTTCCGC
Pst I


912
4082
Forward
AAAAAAGAATTC-
Eco RI





CAAATCCGTCAAAACGCCACTCAAGTATTGAG




4083
Reverse
AAAAAACTGCAG-TTACAGTCCGTCCACGCCTTTCGC
Pst I


913
4084
Forward
CGCGGATCCCATATG-GAAACCCGCCCCGC
BamHI-






NdeI



4085
Reverse
CCCGCTCGAG-AGGTTGTGTTCCAGGTTG
XhoI


915
4086
Forward
CGCGGATCCCATATG-TGCCGGCAGGCGGAA
BamHI-






NdeI



4087
Reverse
CCCGCTCGAG-TTTGAAAATATAGGTATCAGG
XhoI


914
4088
Forward
AAAGAATTC-GACAGAATCGGCGATTTGGAAGCACG
Eco RI



4089
Reverse
AAACTGCAG-CTATATGCGCGGCAGGACGCTCAACGG
Pst I


916
4090
Forward
CGCGGATCCCATATG-GCAATGATGGCGGCTG
BamHI-






NdeI



4091
Reverse
CCCGCTCGAG-TTTGGCGGCATCTTTCAT
XhoI


917
4092
Forward
AAAAAAGAATTC-CCTGCCGAAAAACCGGCACCGGC
Eco RI



4093
Reverse
AAAAAACTGCAG-TTATTTCCCCGCCTTCACATCCTG
Pst I


919
4094
Forward
CGCGGATCCCATATG-TGCCAAAGCAAGAGCATC
BamHI-






NdeI



4095
Reverse
CCCGCTCGAG-CGGGCGGTATTCGGG
XhoI


920
4096
Forward
CGCGGATCCCATATG-CACCGCGTCTGGGTC
BamHI-






NdeI



4097
Reverse
CCCGCTCGAG-ATGGTGCGAATGACCGA
XhoI


921
4098
Forward
AAAAAAGAATTC-TTGACGGAAATCCCCGTGAATCC
Eco RI



4099
Reverse
AAAAAACTGCAG-TCATTTCAAGGGCTGCATCTTCAT
Pst I


922
4100
Forward.2
CGCGGATCCGCTAGC-TGTACGGCGATGGAGGC
BamHI-






NheI



4101
Reverse
CCCGCTCGAG-CAATCCCGGGCCGCC
XhoI


923
4102
Forward
CGCGGATCCCATATG-TGTTACGCAATATTGTCCC
BamHI-






NheI



4103
Reverse
CCCGCTCGAG-GGACAAGGCGACGAAG
XhoI


925
4104
Forward
CGCGGATCCCATATG-AAACAAATGCTTTTAGCCG
BamHI-






NdeI



4105
Reverse
CCCGCTCGAG-GCCGTTGCATTTGATTTC
XhoI


926
4106
Forward
CGCGGATCCCATATG-TGCGCGCAATTACCTC
BamHI-






NdeI



4107
Reverse
CCCGCTCGAG-TCTCGTGCGCGCCG
XhoI


927
4108
Forward
CGCGGATCCCATATG-TGCAGCCCCGCAGC
BamHI-






NdeI



4109
Reverse
CCCGCTCGAG-GTTTTTTGCTGACGTAGT
XhoI


929a
4110
Forward
AAAAAAGAATTC-CGCGGTTTGCTCAAAACAGGGCTGGG
Eco RI



4111
Reverse
AAAAAATCTAGA-TTAAGAAAGACGGAAACTACTGCC
Xba I


931
4112
Forward
AAAAAAGAATTC-GCAACCCATGTTTTGATGGAAAC
Eco RI



4113
Reverse
AAAAAACTGCAG-TTACTGCCCGACAACAACGCGACG
Pst I


935
4114
Forward
AAAAAAGAATTC-
Eco RI





GCGGATGCGCCCGCGATTTTGGATGACAAGGC




4115
Reverse
AAAAAACTGCAG-TCAAAACCGCCAATCCGCCGACAC
Pst I


936
4116
Forward
CGCGGATCCCATATG-GCCGCCGTCGGCGC
BamHI-






NdeI



4117
Reverse
CCCGCTCGAG-GCGTTGGACGTAGTTTTG
XhoI


937
4118
Forward
AAAAAAGAATTC-CCGGTTTACATTCAAACCGGCGCAAC
Eco RI



4119
Reverse
AAAAAACTGCAG-TTAAAATGTATGCTGTACGCCAAA
Pst I


939a
4120
Forward
AAAAAAGAATTC-GGTTCGGCAGCTGTGATGAAACC
Eco RI



4121
Reverse
AAAAAACTGCAG-TTAACGCAAACCTTGGATAAAGTTGGC
Pst I


950
4122
Forward
CGCGGATCCCATATG-GCCAACAAACCGGCAAG
BamHI-






NdeI



4123
Reverse
CCCGCTCGAG-TTTAGAACCGCATTTGCC
XhoI


953
4124
Forward
CGCGGATCCCATATG-GCCACCTACAAAGTGGAC
BamHI-






NdeI



4125
Reverse
CCCGCTCGAG-TTGTTTGGCTGCCTCGAT
XhoI


957
4126
Forward
CGCGGATCCCATATG-TTTTGGCTGGGAACGGG
BamHI-






NdeI



4127
Reverse
CCCGCTCGAG-GTGAGAAAGGTCGCGC
XhoI


958
4128
Forward
CGCGGATCCCATATG-GCCGATGCCGTTGCG
BamHI-






NdeI



4129
Reverse
GCCCAAGCTT-GGGTCGTTTGTTGCGTC
HindIII


959
4130
Forward
CGCGGATCCCATATG-CACCACGACGGACACG
BamHI-






NdeI



4131
Reverse
CCCGCTCGAG-GTCGTCGCGGCGGGA
XhoI


961
4132
Forward
CGCGGATCCCATATG-GCCACAAGCGACGACG
BamHI-






NdeI



4133
Reverse
CCCGCTCGAG-CCACTCGTAATTGACGC
XhoI


972
4134
Forward
AAAAAAGAATTC-
Eco RI





TTGACTAACAGGGGGGGAGCGAAATTAAAAAC




4135
Reverse
AAAAAATCTAGA-TTAAAAATAATCATAATCTACATTTTG
Xba I


973
4136
Forward
AAAAAAGAATTC-ATGGACGGCGCACAACCGAAAAC
Eco RI



4137
Reverse
AAAAAACTGCAG-TTACTTCACGCGGGTCGCCATCAGCGT
Pst I


982
4138
Forward
CGCGGATCCCATATG-GCAGCAAAAGACGTAC
BamHI-






NdeI



4139
Reverse
CCCGCTCGAG-CATCATGCCGCCCATCC
XhoI


983
4140
Forward
CGCGGATCCCATATG-TTAGCTGTTGCAACAACAC
BamHI-






NdeI



4141
Reverse
CCCGCTCGAG-GAACCGGTAGCCTACG
XhoI


987
4142
Forward
CGCGGATCCCATATG-CCCCCACTGGAAGAAC
BamHI-






NdeI



4143
Reverse
CCCGCTCGAG-TAATAAACCTTCTATGGGC
XhoI


988
4144
Forward
CGCGGATCCCATATG-TCTTTAAATTTACGGGAAAAAG
BamHI-






NdeI



4145
Reverse
GCCCAAGCTT-TGATTTGCCTTTCCGTTTT
HindIII


989
4146
Forward
CCGGAATTCTACATATG-GTCCACGCATCCGGCTA
EcoRI-






NdeI



4147
Reverse
CCCGCTCGAG-TTTGAATTTGTAGGTGTATTGC
XhoI


990
4148
Forward.2
CGCGGATCCGCTAGC-TTCAGAGCTCAGCTT
BamHI-






NheI



4149
Reverse
CCCGCTCGAG-AAACAGCCATTTGAGCGA
XhoI


992
4150
Forward
CGCGGATCCCATATG-GACGCGCCCGCCCG
BamHI-






NdeI



4151
Reverse
CCCGCTCGAG-CCAAATGCCCAACCATTC
XhoI


993
4152
Forward
CGCGGATCCCATATG-GCAATGCTGATTGAAATCA
BamHI-






NdeI



4153
Reverse
CCCGCTCGAG-GAACACATCGCGCCCG
XhoI


996
4154
Forward
CGCGGATCCCATATG-TGCGGCAGAAAATCCGC
BamHI-






NdeI



4155
Reverse
CCCGCTCGAG-TCTAAACCCCTGTTTTCTC
XhoI


997
4156
Forward
CCGGAATTCTAGCTAGC-CGGCACGCCGACGTT
EcoRI-






NheI



4157
Reverse
CCCGCTCGAG-GACGGCATCGCTCAGG
XhoI









Underlined sequences indicate restriction recognition sites.

The following DNA and amino acid sequences are identified by titles of the following form: [g, m, or a] [#].[seq or pep], where “g” means a sequence from N. gonorrhoeae, “m” means a sequence from N. meningitidis B, and “a” means a sequence from N. meningitidis A; “#” means the number of the sequence; “seq” means a DNA sequence, and “pep” means an amino acid sequence. For example, “g001.seq” refers to an N. gonorrhoeae DNA sequence, number 1. The presence of the suffix “−1” to these sequences indicates an additional sequence found for the same ORF. Further, open reading frames are identified as ORF #, where “#” means the number of the ORF, corresponding to the number of the sequence which encodes the ORF, and the ORF designations may be suffixed with “.ng” or “.a”, indicating that the ORF corresponds to a N. gonorrhoeae sequence or a N. meningitidis A sequence, respectively. Computer analysis was performed for the comparisons that follow between “g”, “m”, and “a” peptide sequences; and therein the “pep” suffix is implied where not expressly stated.
The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1>:









g001.seq




1
ATGCTGCCGC AGGGGAAGGC GGCGCGGAGG GTGTCGGCGA ACGAGGTGTC


 


51
CGGCAGGGCT TGCGCCCGGA TGGTGCTGGT CATCTGCCAG ACGCTGCCGA


 


101
AACGCGATAC TTTAAACGGC TCGGGTACGC ATACTTTACC GGTTTGGGCG


 


151
ATTTTGCCGA GGTCGTTGCG CAGCAAATCG ACAATCATCA CGTTTTCGGC


 


201
GCGGTTTTTC GGGTCGGTTT GTAACTCGGC GGCGCGGCGT TCGTCTTGTC


 


251
CGTCGCCCAA AATCGGCGCG GTGCCTTTCA TCGGTTCGGT GCTGATGGTG


 


301
CCGTCTGAAG CGATGTTGAG GAAGAGTTCG GGCGAGAAAC ACAGCGTCCA


 


351
CGCGGATTGC CCGGCTTCAT CGGGCAGGTG GGACAATACG GCATAG






This corresponds to the amino acid sequence <SEQ ID 2; ORF 001.ng>:










g001.pep




1
MLPQGKAARR VSANEVSGRA CARMVLVICQ TLPKRDTLNG SGTHTLPVWA


 


51
ILPRSLRSKS TIITFSARFF GSVCNSAARR SSCPSPKIGA VPFIGSVLMV


 


101
PSEAMLRKSS GEKHSVHADC PASSGRWDNT A*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3>:










m001.seq




1
ATGCTGCCGC AGGGGAAGGC GGCGCGGAGG ATGTCGGCGA ACGAGGTGTG


 


51
CGGcAssCTT ss.GCTTGGA yGGTGCTGGT CATCTGCCAA ACGCTGCCGA


 


101
AACGCGATAC TTTAAACGGT TCGGGTACGC ATACTGTGCC GGTTTGGGCG


 


151
ATTTTGCCGA GATCGTTACG CAGCAAATCG ACAATCATCA CGTTTTCGGC


 


201
GCGGTTTTTC GGGTCTGCTT GCAACTCGGC GGCGCGGCGT TCGTCTTGTC


 


251
CGTCGCCCAA AATCGGCGCG GTGCCTTTCA TCGGTTCGGT GCTGATGGTG


 


301
CCGTCCGAAC CGATTTTGAG GAAGAGTTCG GGCGAGAAAC ACAGCGTCCA


 


351
CGCGGATTGC CCCTCCGCAT CGGGCAGGTG GGACAAGACG GCATAG






This corresponds to the amino acid sequence <SEQ ID 4; ORF 001>:










m001.pep




1
MLPQGKAARR MSANEVCGXL XAWXVLVICQ TLPKRDTLNG SGTHTVPVWA


 


51
ILPRSLRSKS TIITFSARFF GSACNSAARR SSCPSPKIGA VPFIGSVLMV


 


101
PSEPILRKSS GEKHSVHADC PSASGRWDKT A*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 5>:










a001.seq




1
ATGCTGCCGC AGGGGAAGGC GGCGCGGAGG ATGTCGGCGA ACGAGGTGTG


 


51
CGGCAAGGCT TGGGCTTGGA TGGTGCTGGT CATCTGCCAA ACGCTGCCGA


 


101
AACGCGATAC TTTAAACGGT TCGGGTACGC ATACTGTGCC GGTTTGGGCG


 


151
ATTTTGCCGA GGTCGTTACG CAGCAAATCG ACAATCATCA CGTTTTCGGC


 


201
GCGGTTTTTC GGGTCTGCTT GCAACTCGGC GGCGCGGCGT TCGTCTTGTC


 


251
CGTCGCCCAA AATCGGCGCG GTGCCTTTCA TCGGTTCGGT GCTGATGGTG


 


301
CCGTCCGAAC CGATTTTGAG GAAGAGTTCG GGCGAGAAAC ACAGCGTCCA


 


351
CGCGGATTGC CCTTGTGCAT CGGGCAGGTG GGACAAAACG GCATAG






This corresponds to the amino acid sequence <SEQ ID 6; ORF 001.a>:










a001.pep




1
MLPQGKAARR MSANEVCGKA WAWMVLVICQ TLPKRDTLNG SGTHTVPVWA


 


51
ILPRSLRSKS TIITFSARFF GSACNSAARR SSCPSPKIGA VPFIGSVLMV


 


101
PSEPILRKSS GEKHSVHADC PCASGRWDKT A*






m001/a001 96.2% identity over a 131 aa overlap




Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 001 shows 89.3% identity over a 131 aa overlap with a predicted ORF (ORF 001.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 7>:










g003.seq




1
ATGGTCGTAT TCGTGGCTGA AGGCGTATTC GGTCGCGCTG TTTTGGGTCA


 


51
CTTGGTATTG CTCTTCGGTC AGGGTGCGTT TGAGTTCGGC GTCACTCGGT


 


101
TTTTTATACG TTGCCGCGTC GAAGCCTTTG CCTTGCGGTG CGGCTTTGGT


 


151
TTTGCCCGGC AGCGGTTCGT CGGCTTTGCG GATGTCGATG TGGCAGTAGC


 


201
CGTTGGGGTT TTTAATCAGG TAGTCCTGAT GGTATTCCTC GGCGTCGTAG


 


251
AAGTTTTTCA GCGGTTCGTT TTCAACAACG AGGGGCAGTT GGTATTTTTG


 


301
CTGCTCGCGT TTGAGGGCGG CGGCGATGAC GGCTTTTTCG GCGGGGTCGG


 


351
TGTAGTACAC GCCGCTGCGG TATTGCGTGC CGGTGTCGTT ACCCTGTTTG


 


401
TTGAGGCTGG TCGGATCAAC GACGCGGAAA TAATATTGCA GGATGTCGTC


 


451
CAGgCTGagt TTGTCGGCAT CGTaggtcac tTTGACGGTC TCGGCATGAC


 


501
CCGTATGGCG GTaggacact tctTCgtanc TcGGGtTTTC CGTGttGCCG


 


551
TTGGCgttac cGGATACCGC gtcaACCACG CCGTcgatgc gttggaAATa


 


601
ggCTTCCAAg ccccaaaagc agccgccggc gaagtaaatg gtgcccgtgt


 


651
tcatgattGC TGa






This corresponds to the amino acid sequence <SEQ ID 8; ORF 003.ng>:










g003.pep




1
MVVFVAEGVF GRAVLGHLVL LFGQGAFEFG VTRFFIRCRV EAFALRCGFG


 


51
FARQRFVGFA DVDVAVAVGV FNQVVLMVFL GVVEVFQRFV FNNEGQLVFL


 


101
LLAFEGGGDD GFFGGVGVVH AAAVLRAGVV TLFVEAGRIN DAEIILQDVV


 


151
QAEFVGIVGH FDGLGMTRMA VGHFFVRVFR VAVGVTGYRV NHAVDALEIG


 


201
FQAPKAAAGE VNGARVHDC






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 9>:










m003.seq




1
ATGGTCGTAT TCGTGGCTGA AGGCATATTC GGTCGCGCTG TTTTGGGTAA


 


51
CTTGsTATTG CTCTTCGGTC AGGGTGCGTT TGAGTTCGGC GTCACTCGGT


 


101
TTTTTATACG TTGCCGCGTC GAAGCCTTTG CCTTGCGGGG CGGTCTTGGT


 


151
TTTGCCCGGC AGCGGTTCGT CAGCkTTGCG GATGTCGATG TGGCAGTAGC


 


201
CGTTGGGGTT TTTAATCAAG TAGTCCTGAT GGTATTCCTC GGCATCGTAG


 


251
AAGTTTTtCA GCGGCTCGTT TTCAACAACG AGGGGCAGTT GGTATTTTTG


 


301
CTGCTCGCGT TTGAGGGCGk CGGCGATGAC GGCTTTTTCG kCGGGGTCGG


 


351
TGTAGTACAC GCCGCTGCGG TATTGCGTAC CGGTGTCGTT GCCCTGTTTG


 


401
TTGAGGCTGG TCGGATCAAC GACGCGGAAG AAATATTGCA GGATGTCGTC


 


451
TAGGCTGAGT TTGTCGGCAT CGTAGGTCAC TTTGACGGTT TCGGCGTGGC


 


501
CCGTATGGCG GTAGGACACG TCTTCATAGC TCGGATTTTT CGTGTTGCCG


 


551
TTGGCGTAGC CGGATACCGC GTCAACCACG CCGTCGATGC GTTGGAAATA


 


601
GGCTTCCAAG CCCCAGAAGC AGCg.CCGGC GAGGTAAATG GTGCGCGTGT


 


651
TCATGATTTT TGA






This corresponds to the amino acid sequence <SEQ ID 10; ORF 003>:









m003.pep Length: 221










1
MVVFVAEGIF GRAVLGNLXL LFGQGAFEFG VTRFFIRCRV EAFALRGGLG



 


51
FARQRFVSXA DVDVAVAVGV FNQVVLMVFL GIVEVFQRLV FNNEGQLVFL


 


101
LLAFEGXGDD GFFXGVGVVH AAAVLRTGVV ALFVEAGRIN DAEEILQDVV


 


151
*AEFVGIVGH FDGFGVARMA VGHVFIARIF RVAVGVAGYR VNHAVDALEI


 


201
GFQAPEAAXG EVNGARVHDF *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 11>:










a003.seq




1
ATGGTCGTAT TCGTGGCTGA AGGCATATTC GGTCGCGCTG TTTTGGGTAA


 


51
CTTGGTATTG CTCTTCGGTC AGGGTGCGTT TGAGTTCGGC GTCACTCGGT


 


101
TTTTTATACG TTGCCGCGTC GAAGCCTTTG CCTTGCGGTG CGGTCTTGGT


 


151
TTTGCCCGGC AGCGGTTCGT CGGCTTTGCG GATATCGATG TGGCAGTAGC


 


201
CGTTGGGGTT TTTAATCAAG TAGTCCTGAT GGTATTCCTC GGCATCGTAG


 


251
AAGTTTTTCA GCGGCTCGTT TTCAACAACG AGGGGCAGTT GGTATTTTTG


 


301
CTGCTCGCGT TTGAGGGCGG CGGCGATGAC GGCTTTTTCG GCGGGGTCGG


 


351
TGTAGTACAC GCCGCTGCGG TATTGCGTAC CGGTGTCGTT GCCCTGTTTG


 


401
TTGAGGCTGG TCGGATCAAC GACGCGGAAG AAATATTGCA GGATGTCGTC


 


451
TAGGCTGAGT TTGTCGGCAT CGTAGGTCAC TTTGACGGTT TCGGCGTGGC


 


501
CCGTATGGCG GTAGGACACG TCTTCATAGC TCGGATTTTT CGTGTTGCCG


 


551
TTGGCGTAGC CGGATACCGC GTCAACCACG CCGTCGATGC GTTGGAAATA


 


601
GGCTTCCAAG CCCCAGAAGC AGCCGCCGGC GAGGTAGATG GTGCGCGTGT


 


651
TCATGATTTT TGA






This corresponds to the amino acid sequence <SEQ ID 12; ORF 003.a>:










a003.pep




1
MVVFVAEGIF GRAVLGNLVL LFGQGAFEFG VTRFFIRCRV EAFALRCGLG


 


51
FARQRFVGFA DIDVAVAVGV FNQVVLMVFL GIVEVFQRLV FNNEGQLVFL


 


101
LLAFEGGGDD GFFGGVGVVH AAAVLRTGVV ALFVEAGRIN DAEEILQDVV


 


151
*AEFVGIVGH FDGFGVARMA VGHVFIARIF RVAVGVAGYR VNHAVDALEI


 


201
GFQAPEAAAG EVDGARVHDF *






m003/a003 95.9% identity over a 220 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 003 shows 88.6% identity over a 219 aa overlap with a predicted ORF (ORF 003.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 13>:










g004.seq




1
ATGgtagAAC GGCATATCCA GCATTTGCGG AACGGTCATC TTCATTTGAT


 


51
GCGCCCATGC CAACAagtga gccaAAtgtT CGGCGGCAGG GCCTacgatT


 


101
TCCGCGCCGA TAAagcggcc gGTGgctTTT tcgGCataca ggcgcaTatg


 


151
gCCTTTGTTT ACCAgcatca cgcggctgcg accttgaTTT TTGAACGATA


 


201
CTTCGCCgaT GACAAATTCG TCGGCTTGGT ATTGCGCGGC AACCTGCGCG


 


251
TATTTCAAAC CGACAAAGCC GATTTGCgga ctggtaaACA CCACGCCAAT


 


301
GGTgctgcgg cGCAAACCGC TGCCGATATt cgGgtagcgg ccccgcgtta


 


351
ttgcccggca atcttacctt ggtcggcggc ttcatGCAGC AGGGGCagtt


 


401
ggttggacgc gtcgcccgca ataAAGATAT GCGGAATgct ggtCTGCATg


 


451
gtCAGCGGAT CGGCAACGGG tacgccgcgc gcgtctttgT CGATATTGAT


 


501
GTTTTCCAAA CCGATATtgT CAACGTTCGG ACGGCgACCT ACGGCTGCCA


 


551
ACATATATTC GGCAACAAAT ACGCCTTTTT CGCCATCCTG CTCCCAATGG


 


601
ACTtctACAT TGCCGTCTGC GTCGAGTTTG ACCTCGGTTT TAGCATCCAG


 


651
ATGCAGTTTC AATtctTCTC CGAACACGGC TTTCGCCTCG TCTGAAACAA


 


701
CGGGGTCGGA AATGCCGCCG ATGATTCCGC CCAAACCGAA AATTTCAACT


 


751
TTCACACCCA AACGGTGCAA TGCCTGA






This corresponds to the amino acid sequence <SEQ ID 14; ORF 004.ng>:










g004.pep




1
MVERHIQHLR NGHLHLMRPC QQVSQMFGGR AYDFRADKAA GGFFGIQAHM


 


51
AFVYQHHAAA TLIFERYFAD DKFVGLVLRG NLRVFQTDKA DLRTGKHHAN


 


101
GAAAQTAADI RVAAPRYCPA ILPWSAASCS RGSWLDASPA IKICGMLVCM


 


151
VSGSATGTPR ASLSILMFSK PILSTFGRRP TAANIYSATN TPFSPSCSQW


 


201
TSTLPSASSL TSVLASRCSF NSSPNTAFAS SETTGSEMPP MIPPKPKIST


 


251
FTPKRCNA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 15>:










m004.seq




1
ATGGTAGAAC GGCATATCCA GCATTTGCGG AACGGTCATC TTCATTTGAT


 


51
GTGCCCAAGC CAACAGGTGC GCCAAATGTT CGGCGGCAGG GCCTACGATT


 


101
TCCGCGCCGA TAAAGCGGCC GGTGGCTTTT TCGGCATACA GGCGCATATG


 


151
GCCTTTGTTC ACCAGCATCA CGCGGCTGCG GCCTTGGTTT TTGAACGATA


 


201
CTTCGCCGAT GACAAATTCG TCGGCTTGGT ATTGCGCGGC AACCTGCGCG


 


251
TATTTCAGAC CGACAAAGCC GATTTGCGGA CTGGTAAACA CCACGCCGAT


 


301
GGTGCTGCGC CGCAAACCGC CGCCGATATT CGGGTAGCGG CCGCGTTATC


 


351
GCCGGCAATC TTGCCTTGGT CGGCAGCTTC ATGCAGCAGA GGCAGTTGGT


 


401
TGGACGCATC GCCTGCGATG AAGATATGCG GAATACTGGT CTGCATGGTC


 


451
AGCGGGTCGG CAACAGGTAC GCCGCGCGCA TCTTTTTCGA TATTGATATT


 


501
TTCCAAACCG ATATTGTCAA CGTTCGGACG GCGGCCCACG GCTGCCAGCA


 


551
TATATTCGGC AACAAATACG CCTTTTTCGC CATCCTGCTC CCAATGGACT


 


601
TCTACATTGC CGTCTGCATC GAGTTTGACC TCGGTTTTAG CATCCAGATG


 


651
CAGTTTCAAT TCTTCGCCGA ACACGGCGTT CGCCTCGTCT GAAACGACGG


 


701
GGTCGGAAAT GCCGCCGATG ATTCCGCCCA AACCGAAAAT TTCAACTTTC


 


751
ACGCCCAAAC GGTGCAATGC CTGA






This corresponds to the amino acid sequence <SEQ ID 16; ORF 004>:










m004.pep




1
MVERHIQHLR NGHLHLMCPS QQVRQMFGGR AYDFRADKAA GGFFGIQAHM


 


51
AFVHQHHAAA ALVFERYFAD DKFVGLVLRG NLRVFQTDKA DLRTGKHHAD


 


101
GAAPQTAADI RVAAALSPAI LPWSAASCSR GSWLDASPAM KICGILVCMV


 


151
SGSATGTPRA SFSILIFSKP ILSTFGRRPT AASIYSATNT PFSPSCSQWT


 


201
STLPSASSLT SVLASRCSFN SSPNTAFASS ETTGSEMPPM IPPKPKISTF


 


251
TPKRCNA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 17>:










a004.seq




1
ATGGTAGAAC GGCATATCCA GCATTTGCGG AACGGTCATC TTCATTTGAT


 


51
GTGCCCAAGC CAACAGGTGC GCCAAATGTT CGGCGGCCGG ACCTACGATT


 


101
TCTGCGCCGA TGAAGCGGCC GGTGGCTTTT TCGGCATACA GGCGCATATG


 


151
GCCTTTGTTT ACCAGCATCA CGCGGCTGCG GCCTTGGTTT TTGAACGATA


 


201
CTTCGCCGAT GACAAATTCG TCGGCTTGGT ATTGCGCGGC AACCTGCGCG


 


251
TATTTCAAAC CGACAAAGCC GATTTGCGGA CTGGTGAACA CTACGCCGAT


 


301
GGTGCTGCGG CGCAAACCGC CGCCGATATT CGGGTAGCGG CCGCGTTATC


 


351
GCCGGCAATC TTGCCTTGGT CGGCGGCTTC ATGCAGCAGG GGCAGTTGGT


 


401
TGGACGCGTC GCCCGCAATA AAGATATGCG GAATACTGGT CTGCATAGTC


 


451
AGCGGATCGG CAACGGGTAC GCCGCGCGCA TCTTTTTCGA TATTGATGTT


 


501
TTCCAAACCG ATATTGTCAA CGTTCGGACG GCGGCCTACG GCTGCCAGCA


 


551
TATATTCGGC AACAAATACG CCTTTTTCGC CATCCTGCTC CCAATGGACT


 


601
TCTACATTGC CGTCTGCGTC GAGTTTGGCC TCGGTTTTAG CATCCAAATG


 


651
CAGTTTCAAT TCTTCACCGA ACACGGCTTT CGCCTCGTCT GAAACGACGG


 


701
GGTCGGAAAT GCCGCCGATG ATGCCACCCA AACCGAAAAT TTCAACTTTC


 


751
ACGCCCAAAC GGTGCAATGC CTGA






This corresponds to the amino acid sequence <SEQ ID 18; ORF 004.a>:










a004.pep




1
MVERHIQHLR NGHLHLMCPS QQVRQMFGGR TYDFCADEAA GGFFGIQAHM


 


51
AFVYQHHAAA ALVFERYFAD DKFVGLVLRG NLRVFQTDKA DLRTGEHYAD


 


101
GAAAQTAADI RVAAALSPAI LPWSAASCSR GSWLDASPAI KICGILVCIV


 


151
SGSATGTPRA SFSILMFSKP ILSTFGRRPT AASIYSATNT PFSPSCSQWT


 


201
STLPSASSLA SVLASKCSFN SSPNTAFASS ETTGSEMPPM MPPKPKISTF


 


251
TPKRCNA*






m004/a004 94.9% identity over a 257 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 004 shows 93.4% identity over a 258 aa overlap with a predicted ORF (ORF 004.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 19>:










g005.seq




1
ATGGGGATGG ACAATATTGA TATGTTCATG CCTGAACAAG AGGAAATCCA


 


51
ATCAATGTGG AAAGAAATTT TACTGAATTA CGGTATTTTC CTGCTCGAAC


 


101
TGCTTACCGT GTTCGGCGCA ATTGCGCTGA TTGTGTTGGC TATCGTACAG


 


151
AGTAAGAAAC AGTCGGAAAG CGGCAGTGTC GTACTGACAG ATTTTTCGGA


 


201
AAATTATAAA AAACAGCGGC AATCGTTTGA AACATTCTTT TTAAGCGAGG


 


251
AAGAGACAAA ACATCAGGAA AAAAAAGAAA AGAAAAAGGA AAAGGCGGAA


 


301
GCCAAAGCAG AGAAAAAGCG TTTGAAGGAG GGCGGGGAGA AATCTGCCGA


 


351
AACGCAAAAA TCCCGCCTTT TTGTGTTGGA TTTTGACGGC GATTTGTATG


 


401
CACACGCCGT AGAATCCTTG CGTCATGAGA TTACGGCGGT GCTTTTGATT


 


451
GCCAAGCCTG AAGATGAGGT TCTGCTCAGA TTGGAAAGTC CGGGCGGCGT


 


501
GGTTCACGGT TACGGTTTGG CGGCTTCGCA GCTTAGGCGT TTGCGCGAAC


 


551
GCAATATTCC GCTGAccgtc gccgTCGATA AGGTCGCGGC AAGCGgcggc


 


601
tatatgatgg cgtgtgtgGC GGATAAAATT GTTTCCGCtc cgtttgcggt


 


651
catcggttcg gtgggtgtgg tgGcggaagt gcCGAATATC CAccgCctGT


 


701
TGAAAAAACA TGATATTGAT GTGGATGTGA TGACGGCGGG CGAATTTAAG


 


751
CGCACGGTTA CTTTTATGGG TGAAAATACG GAAAAGGGCA AACAGAAATT


 


801
CCGGCAGGAA CTGGAGGAAA CGCATCAGTT GTTCAAGCAG TTTGTCAGTG


 


851
AAAACCGCCC CGGGTTGGAT ATTGAAAAAA TAGCGACGGG CGAGCATTGG


 


901
TTCGGCCGGC AGGCGTTGGC GTTGAACTTG ATTGACGAGA TTTCGACCAG


 


951
TGATGATTTG TTGTTGAAAG CGTTTGAAAA CAAACAGGtt aTCGAAGTGA


 


1001
AATATCAGGA GAAGCGAAGC CTGATCCAGC GCATTGGTTT GCAGGCGGAA


 


1051
GCTTCCGTTG AAAAGTTGTT TGCCAAACTT GTCAACCGGC GAGCGGATGT


 


1101
GATGTAG






This corresponds to the amino acid sequence <SEQ ID 20; ORF 005.ng>:










g005.pep




1
MGMDNIDMFM PEQEEIQSMW KEILLNYGIF LLELLTVFGA IALIVLAIVQ


 


51
SKKQSESGSV VLTDFSENYK KQRQSFETFF LSEEETKHQE KKEKKKEKAE


 


101
AKAEKKRLKE GGEKSAETQK SRLFVLDFDG DLYAHAVESL RHEITAVLLI


 


151
AKPEDEVLLR LESPGGVVHG YGLAASQLRR LRERNIPLTV AVDKVAASGG


 


201
YMMACVADKI VSAPFAVIGS VGVVAEVPNI HRLLKKHDID VDVMTAGEFK


 


251
RTVTFMGENT EKGKQKFRQE LEETHQLFKQ FVSENRPGLD IEKIATGEHW


 


301
FGRQALALNL IDEISTSDDL LLKAFENKQV IEVKYQEKRS LIQRIGLQAE


 


351
ASVEKLFAKL VNRRADVM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 21>:










m005.seq




1
ATGGACAATA TTGACATGTT CATGCCTGAA CAAGAGGAAA TCCAATCAAT


 


51
GTGGAAAGAA ATTTTACTGA ATTACGGTAT TTTCCTGCTC GAACTGCTTA


 


101
CCGTGTTCGG CGCAATTGCG CTGATTGTGT TGGCTATCGT ACAGAGTAAG


 


151
AAACAGTCGG AwAGCGGCAG TGTCGTACTG ACGGATTTTT CGGAAAATTA


 


201
TAAAAAACAG CGGCAATCGT TTGAAGCATT CTTTTTAAGC GGGGAAGAGG


 


251
CACAACATCA GGAAAAAGAG GAAAAGAAAA AGGAAAAGGC GGAAGCCAAA


 


301
GCAGAGAAAA A.CGTTTGAA GGAGGGTGGG GAGAAATCTG CCGAAACGCA


 


351
nAAATCACGC CTTTTTGTGT TGGANNNNNN NNNNNNNNNN NNNNNNNNNN


 


401
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN


 


451
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN


 


501
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN


 


551
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNGCGAGCGG CGGTTATATG


 


601
ATGGCGTGTG TGGCGGATAA AATTGCTTCC GCTCCGTTTG CGATTGTCGG


 


651
TTCGGTGGGT GTGGTGGCGG AAGTACCGAA TATCCACCGC CTGTTGAAAA


 


701
AACATGATAT TGATGTGGAT GTGATGACGG CGGGCGAATT TAAGCGCACG


 


751
GTTACTTTTA TGGGTGAAAA TACGGAAAAG GGCAAACAGA AATTCCGACA


 


801
GGAACTGGAG GAAACGCATC AGTTGTTCAA GCAGTTTGTC AGCGAGAACC


 


851
GCCCTCAATT GGATATTGAG GAAGTGGCAA CGGGCGAGCA TTGGTTCGGT


 


901
CGGCAGGCGT TGGCGTTGAA CTTGATTGAC GAGATTTCGA CCAGTGATGA


 


951
TTTGTTGTTG AAAGCGTTTG AAAACAAACA GGTTATCGAA GTGAAATATC


 


1001
AGGAGAAGCA AAGCCTGATC CAGCGCATTG GTTTGCAGGC GGAAGCTTCT


 


1051
GTTGAAAAGT TGTTTGCCAA ACTTGTCAAC CGGCGGGCGG ATGTGATGTA


 


1101
G






This corresponds to the amino acid sequence <SEQ ID 22; ORF 005>:










m005.pep




1
MDNIDMFMPE QEEIQSMWKE ILLNYGIFLL ELLTVFGAIA LIVLAIVQSK


 


51
KQSXSGSVVL TDFSENYKKQ RQSFEAFFLS GEEAQHQEKE EKKKEKAEAK


 


101
AEKXRLKEGG EKSAETXKSR LFVLXXXXXX XXXXXXXXXX XXXXXXXXXX


 


151
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXASGGYM


 


201
MACVADKIAS APFAIVGSVG VVAEVPNIHR LLKKHDIDVD VMTAGEFKRT


 


251
VTFMGENTEK GKQKFRQELE ETHQLFKQFV SENRPQLDIE EVATGEHWFG


 


301
RQALALNLID EISTSDDLLL KAFENKQVIE VKYQEKQSLI QRIGLQAEAS


 


351
VEKLFAKLVN RRADVM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 23>:










a005.seq




1
ATGGACAATA TTGACATGTT CATGCCTGAA CAAGAGGAAA TCCAATCAAT


 


51
GTGGAAAGAA ATTTTACTGA ATTACGGTAT TTTCCTGCTC GAACTGCTTA


 


101
CCGTGTTCGG CGCAATTGCG CTGATTGTGT TGGCTATCGT ACAGAGTAAG


 


151
AAACAGTCGG AAAGCGGCAG TGTCGTACTG ACGGATTTTT CGGAAAATTA


 


201
TAAAAAACAG CGGCAATCGT TTGAAGCATT CTTTTTAAGC GGGGAAGAGG


 


251
CAAAACATCA GGAAAAAGAG GAAAAGAAAA AGGAAAAGGC GGAAGCCAAA


 


301
GCAGAGAAAA AGCGTTTGAA GGAGGGTGGG GAGAAATCTT CCGAAACGCA


 


351
AAAATCCCGC CTTTTTGTGT TGGATTTTGA CGGCGATTTG TATGCACACG


 


401
CCGTAGAATC CTTGCGTCAT GAGATTACGG CGGTGCTTTT GATTGCCAAG


 


451
CCTGAAGATG AGGTTCTGCT TAGATTGGAA AGTCCGGGCG GCGTGGTTCA


 


501
CGGTTACGGT TTGGCGGCTT CGCAGCTTAG GCGTTTGCGC GAACGCAATA


 


551
TTCCGCTGAC CGTCGCCGTC GATAAGGTGG CGGCGAGCGG TGGTTATATG


 


601
ATGGCGTGTG TGGCGGATAA AATTGTTTCC GCTCCGTTTG CGATTGTCGG


 


651
TTCGGTGGGT GTTGTAGCGG AAGTACCGAA TATCCACCGC CTGTTGAAAA


 


701
AACATGATAT TGATGTGGAT GTGATGACGG CGGGCGAATT TAAGCGCACG


 


751
GTTACTTTTA TGGGTGAAAA TACGGAAAAG GGCAAACAGA AATTCCGACA


 


801
GGAACTGGAG GAAACGCATC AGTTGTTCAA GCAGTTTGTC AGCGAGAACC


 


851
GCCCTCAATT GGATATTGAG GAAGTGGCAA CGGGCGAGCA TTGGTTCGGT


 


901
CGGCAGGCGT TGGCGTTGAA CTTGATTGAC GAGATTTCGA CCAGTGATGA


 


951
TTTGTTGTTG AAAGCGTTTG AAAACAAACA GGTTATCGAA GTGAAATATC


 


1001
AGGAGAAGCA AAGCCTGATC CAGCGCATTG GTTTGCAGGC GGAAGCTTCT


 


1051
GTTGAAAAGT TGTTTGCCAA ACTTGTCAAC CGGCGGGCGG ATGTGATGTA


 


1101
G






This corresponds to the amino acid sequence <SEQ ID 24; ORF 005.a>:










a005.pep




1
MDNIDMFMPE QEEIQSMWKE ILLNYGIFLL ELLTVFGAIA LIVLAIVQSK


 


51
KQSESGSVVL TDFSENYKKQ RQSFEAFFLS GEEAKHQEKE EKKKEKAEAK


 


101
AEKKRLKEGG EKSSETQKSR LFVLDFDGDL YAHAVESLRH EITAVLLIAK


 


151
PEDEVLLRLE SPGGVVHGYG LAASQLRRLR ERNIPLTVAV DKVAASGGYM


 


201
MACVADKIVS APFAIVGSVG VVAEVPNIHR LLKKHDIDVD VMTAGEFKRT


 


251
VTFMGENTEK GKQKFRQELE ETHQLFKQFV SENRPQLDIE EVATGEHWFG


 


301
RQALALNLID EISTSDDLLL KAFENKQVIE VKYQEKQSLI QRIGLQAEAS


 


351
VEKLFAKLVN RRADVM*






m005/a005 79.2% identity over a 366 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 005 shows 77.0% identity over a 366 aa overlap with a predicted ORF (ORF 005.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 25>:










g006.seq




1
ATGCTGCTGG TGCTggaatt ttggttCGGc gtGtCGGCGG TGGGCatact


 


51
tgCGTTGTTT TTATGGCttt TGCCACGTTT TGCCGCCATC AGCGAAAACC


 


101
TGTATTTCCG CCTGAACAAC AGCTTGGAAC gcgACAACCA CTTTATCCGA


 


151
AAAGGCGACG AGCGGCAGCT GTACCGCCAT TACGGACTGG TTTCGCGCCT


 


201
GCGTGTGCTG ATTTCCAACC GCGAAGCCTT CGGCTATCTC TGCGTCGGCG


 


251
CGGCGATGGG TATTTTGTTC GGCTTTGCTT TTGTGATGAT GACGCTCAAA


 


301
GGCTACGGCA GCGCGGGGCA TATTTATTCG GTCGGCACTT ATCTGTGGAT


 


351
GTTTGCCATG AGTTTGGACG ATGTGCCGCG ATTGGTCGAA CAATATTCCA


 


401
ATTTGAAAGA CATCGGACAA CGGATAGAGT GGTCGGAACG GAACATCAAA


 


451
GCCGGAACTT GA






This corresponds to the amino acid sequence <SEQ ID 26; ORF 006.ng>:










g006.pep




1
MLLVLEFWFG VSAVGILALF LWLLPRFAAI SENLYFRLNN SLERDNHFIR


 


51
KGDERQLYRH YGLVSRLRVL ISNREAFGYL CVGAAMGILF GFAFVMMTLK


 


101
GYGSAGHIYS VGTYLWMFAM SLDDVPRLVE QYSNLKDIGQ RIEWSERNIK


 


151
AGT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 27>:










m006.seq




1
ATGCTGCTGG TGCTGGAATT TTGGGTCGGC GTGTCGGCGG TGGGCATACT


 


51
TGCGTTGTTT TTATGGCTTT TGCCACGTTT TGCCGCCATC AGCGAAAACC


 


101
TGTATTTCCG CCTGAACAAC AGCTTGGAAC GCGACAACCA CTTTATCCGA


 


151
AAAGGCGACC GGCGGCAGCT GTACCGCCAT TACGGACTGC TTGCGCGCCT


 


201
GCGTGTGCTG ATTTCCAACC GCGAAGCCTT CGGCTATCTC TGCGTCGGCA


 


251
CGGCGATGGG TATTTTGTTC GGCTTTGCTT TTGTGATGAT GACGCTCAAA


 


301
GGCTACAGCA GCGCGGGGCA TGTCTATTCG GTCGGCACTT ATCTGTGGAT


 


351
GTTTGCCATG AGTTTGGACG ACGTGCCGCG ATTGGTCGAA CAATATTCCA


 


401
ATTTGAAAGA CATCGGACAA CGGATAGAGT GGTCGGAACG GAACATCAAA


 


451
GCCGGAACTTGA






This corresponds to the amino acid sequence <SEQ ID 28; ORF 006>:










m006.pep




1
MLLVLEFWVG VSAVGILALF LWLLPRFAAI SENLYFRLNN SLERDNHFIR


 


51
KGDRRQLYRH YGLLARLRVL ISNREAFGYL CVGTAMGILF GFAFVMMTLK


 


101
GYSSAGHVYS VGTYLWMFAM SLDDVPRLVE QYSNLKDIGQ RIEWSERNIK


 


151
AGT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 29>:










a006.seq




1
ATGCTGCTGG TGCTGGAATT TTGGGTCGGC GTGTCGGCGG TGGGCATACT


 


51
TGCGTTGTTT TTATGGCTTT TGCCACGTTT TGCCGCCATC AGCGAAAACC


 


101
TGTATTTCCG CCTGAAGAAC AGCTTGGAAC GCGACAACCA CTTTATCCGA


 


151
AAAGGCGACG AGCGGCAGCT GGACCGCCAT TACGGACTGC TTGCGCGCCT


 


201
GCGTGTGCTG ATTTCCAACC GCGAAGCCTT CGGCTATCTC TGCGTCGGCA


 


251
CGGCGATGGG TATTTTGTTC GGCTTTGCTT TTGTGATGAT GACGCTCAAA


 


301
GGCTACAGCA GCGCGGGGCA TGTCTATTCG GTCGGCACTT ATCTGTGGAT


 


351
GTTTGCCATA AGTTTGGACG ACGTGCCGCG ATTGGTCGAA CAATATTCCA


 


401
ATTTGAAAGA CATCGGACAA CGGATAGAGT GGTCGAAACG GAACATCAAA


 


451
GCCGGAACTT GA






This corresponds to the amino acid sequence <SEQ ID 30; ORF 006.a>:










a006.pep




1
MLLVLEFWVG VSAVGILALF LWLLPRFAAI SENLYFRLKN SLERDNHFIR


 


51
KGDERQLDRH YGLLARLRVL ISNREAFGYL CVGTAMGILF GFAFVMMTLK


 


101
GYSSAGHVYS VGTYLWMFAI SLDDVPRLVE QYSNLKDIGQ RIEWSKRNIK


 


151
AGT*






m006/a006 96.7% identity over a 153 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 006 shows 95.4% identity over a 153 aa overlap with a predicted ORF (ORF 006.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 31>:










g006-1.seq




1
ATGTGGAAAA TGTTGAAACA CATAGCCAAA ACCCACCGCA AGCGATTGAT


 


51
TGGCACATTT TCCCCGGTCG GACTGGAAAA CCTTTTGATG CTGGGGTATC


 


101
CGGTGTTTGG CGGCTGGGCG ATTAATGCCG TGATTGCGGG GAGGGTGTGG


 


151
CAGGCGTTGC TGTACGCTTT GGTTGTATTT TTGATGTGGC TGGTCGGTGC


 


201
GGCACGGCGG ATTGCCGATA CGCGCACGTT TACGCGGATT TATACCGAAA


 


251
TCGCCGTGCC GGTTGTGTTG GAACAACGGC AGCGGCAAGT CCCGCATTCA


 


301
GCGGTAACTG CACGGGTTGC CCTGTCGCGT GAATTTGTCA GCTTTTTTGA


 


351
AGAACACCTG CCGATTGCCG CGACATCCGT CGTATCCATA TTCGGCGCGT


 


401
GCATCATGCT GCTGGTGCTG GAATTTTGGG TCGGCGTGTC GGCGGTGGGC


 


451
ATACTTGCGT TGTTTTTATG GCTTTTGCCA CGTTTTGCCG CCATCAGCGA


 


501
AAACCTGTAT TTCCGCCTGA ACAACAGCTT GGAACGCGAC AACCACTTTA


 


551
TCCGAAAAGG CGACGAGCGG CAGCTGTACC GCCATTACGG ACTGGTTTCG


 


601
CGCCTGCGTG TGCTGATTTC CAACCGCGAA GCCTTCGGCT ATCTCTGCGT


 


651
CGGCGCGGCG ATGGGTATTT TGTTCGGCTT TGCTTTTGTG ATGATGACGC


 


701
TCAAAGGCTA CGGCAGCGCG GGGCATATTT ATTCGGTCGG CACTTATCTG


 


751
TGGATGTTTG CCATGAGTTT GGACGATGTG CCGCGATTGG TCGAACAATA


 


801
TTCCAATTTG AAAGACATCG GACAACGGAT AGAGTGGTCG GAACGGAACA


 


851
TCAAAGCCGG AACTTGA






This corresponds to the amino acid sequence <SEQ ID 32; ORF 006-1.ng>:










g006-1.pep




1
MWKMLKHIAK THRKRLIGTF SPVGLENLLM LGYPVFGGWA INAVIAGRVW


 


51
QALLYALVVF LMWLVGAARR IADTRTFTRI YTEIAVPVVL EQRQRQVPHS


 


101
AVTARVALSR EFVSFFEEHL PIAATSVVSI FGACIMLLVL EFWVGVSAVG


 


151
ILALFLWLLP RFAAISENLY FRLNNSLERD NHFIRKGDER QLYRHYGLVS


 


201
RLRVLISNRE AFGYLCVGAA MGILFGFAFV MMTLKGYGSA GHIYSVGTYL


 


251
WMFAMSLDDV PRLVEQYSNL KDIGQRIEWS ERNIKAGT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 33>:










m006-1.seq




1
ATGTGGAAAA TGTTGAAACA CATAGCCCAA ACCCACCGCA AGCGATTGAT


 


51
TGGCACATTT TCCCTGGTCG GACTGGAAAA CCTTTTGATG CTGGTGTATC


 


101
CGGTGTTTGG CGGCCGGGCG ATCAATGCCG TGATTGCGGG GGAGGTGTGG


 


151
CAGGCGTTGC TGTACGCTTT GGTTGTGCTT TTGATGTGGC TGGTCGGTGC


 


201
GGTGCGGCGG ATTGCCGATA CGCGCACGTT TACGCGGATT TATACCGAAA


 


251
TCGCCGTGCC GGTCGTGTTG GAACAGCGGC AGCGACAAGT CCCGCATTCG


 


301
GCGGTAACTG CGCGGGTTGC CCTGTCGCGT GAGTTTGTCA GCTTTTTTGA


 


351
AGAACACCTG CCGATTGCCG CGACATCCGT CGTATCCATA TTCGGCGCGT


 


401
GCATCATGCT GCTGGTGCTG GAATTTTGGG TCGGCGTGTC GGCGGTGGGC


 


451
ATACTTGCGT TGTTTTTATG GCTTTTGCCA CGTTTTGCCG CCATCAGCGA


 


501
AAACCTGTAT TTCCGCCTGA ACAACAGCTT GGAACGCGAC AACCACTTTA


 


551
TCCGAAAAGG CGACCGGCGG CAGCTGTACC GCCATTACGG ACTGCTTGCG


 


601
CGCCTGCGTG TGCTGATTTC CAACCGCGAA GCCTTCGGCT ATCTCTGCGT


 


651
CGGCACGGCG ATGGGTATTT TGTTCGGCTT TGCTTTTGTG ATGATGACGC


 


701
TCAAAGGCTA CAGCAGCGCG GGGCATGTCT ATTCGGTCGG CACTTATCTG


 


751
TGGATGTTTG CCATGAGTTT GGACGACGTG CCGCGATTGG TCGAACAATA


 


801
TTCCAATTTG AAAGACATCG GACAACGGAT AGAGTGGTCG GAACGGAACA


 


851
TCAAAGCCGG AACTTGA






This corresponds to the amino acid sequence <SEQ ID 34; ORF 006-1>:










m006-1.pep




1
MWKMLKHIAQ THRKRLIGTF SLVGLENLLM LVYPVFGGRA INAVIAGEVW


 


51
QALLYALVVL LMWLVGAVRR IADTRTFTRI YTEIAVPVVL EQRQRQVPHS


 


101
AVTARVALSR EFVSFFEEHL PIAATSVVSI FGACIMLLVL EFWVGVSAVG


 


151
ILALFLWLLP RFAAISENLY FRLNNSLERD NHFIRKGDRR QLYRHYGLLA


 


201
RLRVLISNRE AFGYLCVGTA MGILFGFAFV MMTLKGYSSA GHVYSVGTYL


 


251
WMFAMSLDDV PRLVEQYSNL KDIGQRIEWS ERNIKAGT*






m006-1/g006-1 95.5% identity in 288 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 35>:









a006-1.seq (partial)










1
..AGCCAAAACC ACCGCAAGCG ATTGATTGGC ACATTTTTTC TGGTCGGACT



 


51
  GGAAAACCTT TTGATGCTGG TGTATCCGGT GTTTGGCGGC TGGGCGATTA


 


101
  ATGCCGTGAT TGCGGGGCAG GCGTGGCAGG CGTTGCTGTA CGCTTTGGTT


 


151
  GTGCTTTTGA TGTGGCTGGT CGGTGCGGCG CGGCGGATTG CCGATACGCG


 


201
  CACGTTTACG CGGATTTATA CCGAAATCGC CGTGCCGGTT GTGTTGGAAC


 


251
  AGCGGCAGCG GCAAGTCCCG CATTCGGCGG TAACTGCGCG GGTTGCCCTG


 


301
  TCGCGTGAGT TTGTCAGCTT TTTTGAAGAA CACCTGCCGA TTGCCGCGAC


 


351
  ATCCGTCGTA TCCATATTCG GCGCGTGCAT CATGCTGCTG GTGCTGGAAT


 


401
  TTTGGGTCGG CGTGTCGGCG GTGGGCATAC TTGCGTTGTT TTTATGGCTT


 


451
  TTGCCACGTT TTGCCGCCAT CAGCGAAAAC CTGTATTTCC GCCTGAAGAA


 


501
  CAGCTTGGAA CGCGACAACC ACTTTATCCG AAAAGGCGAC GAGCGGCAGC


 


551
  TGGACCGCCA TTACGGACTG CTTGCGCGCC TGCGTGTGCT GATTTCCAAC


 


601
  CGCGAAGCCT TCGGCTATCT CTGCGTCGGC ACGGCGATGG GTATTTTGTT


 


651
  CGGCTTTGCT TTTGTGATGA TGACGCTCAA AGGCTACAGC AGCGCGGGGC


 


701
  ATGTCTATTC GGTCGGCACT TATCTGTGGA TGTTTGCCAT AAGTTTGGAC


 


751
  GACGTGCCGC GATTGGTCGA ACAATATTCC AATTTGAAAG ACATCGGACA


 


801
  ACGGATAGAG TGGTCGAAAC GGAACATCAA AGCCGGAACT TGA






This corresponds to the amino acid sequence <SEQ ID 36; ORF 006-1.a>:









a006-1.pep (partial)










1
..SQNHRKRLIG TFFLVGLENL LMLVYPVFGG WAINAVIAGQ AWQALLYALV



 


51
  VLLMWLVGAA RRIADTRTFT RIYTEIAVPV VLEQRQRQVP HSAVTARVAL


 


101
  SREFVSFFEE HLPIAATSVV SIFGACIMLL VLEFWVGVSA VGILALFLWL


 


151
  LPRFAAISEN LYFRLKNSLE RDNHFIRKGD ERQLDRHYGL LARLRVLISN


 


201
  REAFGYLCVG TAMGILFGFA FVMMTLKGYS SAGHVYSVGT YLWMFAISLD


 


251
  DVPRLVEQYS NLKDIGQRIE WSKRNIKAGT *






a006-1/m006-1 95.7% identity in 280 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 37>:










g007.seq




1
atgaACACAA CCCGACTGCC GACCGCCTTC ATCTTGTGCT GCCTCTGcgC


 


51
CGCcGCTTCT GCCGccgaca acAGCatcat gaCaAAAGGG CAAAAAGTGT


 


101
ACGAATCcAa ctGCATCGCC TGCCACGGCA AGAAAGGGGA AGGGCGCGGC


 


151
ACTGCGtTTC CTccgctTTT CCggtcgGac tgtattatga acaAACCGCa


 


201
cgTCCtgctg cacagcatgg tcaaaggcAt cgacgggaca ttcaaagtgg


 


251
agcggcaaaa cctacgacgg atttatgCcc gcaaccgcca tcagcgATGC


 


301
GGACATTGCC GCCGTCGCCA CTTATATCAT GAACGCCTTT GA






This corresponds to the amino acid sequence <SEQ ID 38; ORF 007.ng>:










g007.pep




1
MNTTRLPTAF ILCCLCAAAS AADNSIMTKG QKVYESNCIA CHGKKGEGRG


 


51
TAFPPLFRSD CIMNKPHVLL HSMVKGIDGT FKVERQNLRR IYARNRHQRC


 


101
GHCRRRHLYH ERL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 39>:










m007.seq




1
ATGAACACAA CCCGACTGCC GACCGCCCTC GTCTTGGGCT GCTTCTGCGC


 


51
CGCCGCTTCT GCCGCCGACA ACAGCATCAT GACAAAAGGG CAAAAAGTGT


 


101
ACGAATCCAA CTGCGTCGCC TGCCACGGCA AAAAGGGCGA AGGCCGCGGA


 


151
ACCATGTTTC CGCCGCTCTA CCGCTCCGAC TTCATCATGA AAAAACCGCA


 


201
GGTGCTGCTG CACAGCATGG TCAAAGGCAT CAACGGTACA ATCAAAGTC.


 


251
AACGGCAAAA CCTACAACGG ATTCATGCCC GCAACCGCCA TCAGCGATGC


 


301
GGACATTGCC GCCGTCGCCA CTTATATCAT GAACGCCTTT GA






This corresponds to the amino acid sequence <SEQ ID 40; ORF 007>:










m007.pep




1
MNTTRLPTAL VLGCFCAAAS AADNSIMTKG QKVYESNCVA CHGKKGEGRG


 


51
TMFPPLYRSD FIMKKPQVLL HSMVKGINGT IKVXRQNLQR IHARNRHQRC


 


101
GHCRRRHLYH ERL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 41>:










a007.seq




1
ATGAACACAA CCCGACTGCC GACCGCCCTC GTCTTGGGCT GCCTCTGCGC


 


51
CGCCGCTTCT GCCGCCGACA ACAGCATCAT GACAAAAGGG CAAAAAGTGT


 


101
ACGAATCCAA CTGCGTCGCC TGCCACGGCA AAAAGGGCGA AGGCCGCGGA


 


151
ACCATGTTTC CGCCGCTCTA CCGCTCCGAC TTCATCATGA AAAAACCGCA


 


201
GGTGCTGCTG CACAGCATGG TCAAAGGCAT CAACGGTACA ATCAAAGTC.


 


251
AACGGCAAAA CCTACAACGG ATTCATGCCC GCCACTGCCA TCAGCGATGC


 


301
GGACATTGCC GCCGTCGCCA CTTATATCAT GAACGCCTTT GA






This corresponds to the amino acid sequence <SEQ ID 42; ORF 007.a>:










a007.pep




1
MNTTRLPTAL VLGCLCAAAS AADNSIMTKG QKVYESNCVA CHGKKGEGRG


 


51
TMFPPLYRSD FIMKKPQVLL HSMVKGINGT IKVXRQNLQR IHARHCHQRC


 


101
GHCRRRHLYH ERL*






m007/a007 97.3% identity over a 113 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 007 shows 86.7% identity over a 113 aa overlap with a predicted ORF (ORF 007.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 43>:









g007-1.seq (partial)










1
ATGAACACAA CCCGACTGCC GACCGCCTTC ATCTTGTGCT GCCTCTGCGC



 


51
CGCCGCTTCT GCCGCCGACA ACAGCATCAT GACAAAAGGG CAAAAAGTGT


 


101
ACGAATCCAA CTGCATCGCC TGCCACGGCA AGAAAGGGGA AGGGCGCGGC


 


151
ACTGCGTTTC CTCCGCTTTT CCGGTCGGAC TATATTATGA ACAAACCGCA


 


201
CGTCCTGCTG CACAGCATGG TCAAAGGCAT CAACGGTACA ATCAAAGTCA


 


251
ACGGCAAAAC CTACAACGGA TTCATGCCCG CAACCGCCAT CAGCGATGCG


 


301
GACATTGCCG CCGTCGCCAC TTATATCATG AACGCCTTTG ACAACGGCGG


 


351
CGGAAGCGTT ACCGAAAAAG ACGTAAAACA GGCAAAAGGC AAAAAAAAC.






This corresponds to the amino acid sequence <SEQ ID 44; ORF 007-1.ng>:









g007-1.pep (partial)










1
MNTTRLPTAF ILCCLCAAAS AADNSIMTKG QKVYESNCIA CHGKKGEGRG



 


51
TAFPPLFRSD YIMNKPHVLL HSMVKGINGT IKVNGKTYNG FMPATAISDA


 


101
DIAAVATYIM NAFDNGGGSV TEKDVKQAKG KKN...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 45>:










m007-1.seq




1
ATGAACACAA CCCGACTGCC GACCGCCCTC GTCTTGGGCT GCTTCTGCGC


 


51
CGCCGCTTCT GCCGCCGACA ACAGCATCAT GACAAAAGGG CAAAAAGTGT


 


101
ACGAATCCAA CTGCGTCGCC TGCCACGGCA AAAAGGGCGA AGGCCGCGGA


 


151
ACCATGTTTC CGCCGCTCTA CCGCTCCGAC TTCATCATGA AAAAACCGCA


 


201
GGTGCTGCTG CACAGCATGG TCAAAGGCAT CAACGGTACA ATCAAAGTCA


 


251
ACGGCAAAAC CTACAACGGA TTCATGCCCG CAACCGCCAT CAGCGATGCG


 


301
GACATTGCCG CCGTCGCCAC TTATATCATG AACGCCTTTG ACAACGGCGG


 


351
CGGAAGCGTT ACCGAAAAAG ACGTAAAACA GGCAAAAAGC AAAAAAAACT


 


401
AA






This corresponds to the amino acid sequence <SEQ ID 46; ORF 007-1>










m007-1.pep




1
MNTTRLPTAL VLGCFCAAAS AADNSIMTKG QKVYESNCVA CHGKKGEGRG


 


51
TMFPPLYRSD FIMKKPQVLL HSMVKGINGT IKVNGKTYNG FMPATAISDA


 


101
DIAAVATYIM NAFDNGGGSV TEKDVKQAKS KKN*






m007-1/g007-1 91.7% identity in 133 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 47>:









a007-1.seq (partial)










1
ATGAACACAA CCCGACTGCC GACCGCCCTC GTCTTGGGCT GCCTCTGCGC



 


51
CGCCGCTTCT GCCGCCGACA ACAGCATCAT GACAAAAGGG CAAAAAGTGT


 


101
ACGAATCCAA CTGCGTCGCC TGCCACGGCA AAAAGGGCGA AGGCCGCGGA


 


151
ACCATGTTTC CGCCGCTCTA CCGCTCCGAC TTCATCATGA AAAAACCGCA


 


201
GGTGCTGCTG CACAGCATGG TCAAAGGCAT CAACGGTACA ATCAAAGTCA


 


251
ACGGCAAAAC CTACAACGGA TTCATGCCCG CCACTGCCAT CAGCGATGCG


 


301
GACATTGCCG CCGTCGCCAC TTATATCATG AACGCCTTTG ACAACGGCGG


 


351
CGGAAGCGTT ACCGAAAAAG ACGTAAAACA GGCAAAAAAC AAAAAA..






This corresponds to the amino acid sequence <SEQ ID 48; ORF 007-1.a>:









a007-1.pep (partial)










1
MNTTRLPTAL VLGCLCAAAS AADNSIMTKG QKVYESNCVA CHGKKGEGRG



 


51
TMFPPLYRSD FIMKKPQVLL HSMVKGINGT IKVNGKTYNG FMPATAISDA


 


101
DIAAVATYIM NAFDNGGGSV TEKDVKQAKN KK..






m007-1/a007-1 98.5% identity in 132 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 49>:










g008.seq




1
ATGAACAACA GACATTTTGC CGTCAtcgCC TTGGGCAGCA ACCTTGACAA


 


51
CCCCGCACAA CAAATacgcg gcgcattaga cgcgctctcg tcccatcctg


 


101
acatccggct tgaaCaggtt tcctcactgt aTatgaccgc acctgtcggt


 


151
tacgAcaaTC agcccgATTT CATCaatgcc gTCTgcaccg TTTCCACCAC


 


201
CtTGGACGGC ATTGcccTGC TTGCCgaACT CAAccgTATC GAAGCCGATT


 


251
TCGGACGCGA aCGCAGTTTC CGCAATGCAC CGCGCACATT GGATTTGGAC


 


301
ATTATCGACT TTGACGGCAT CTCCAGCGAC GACCCCCGCC TTACCCTGCC


 


351
GCATCCGCGC GCGCACGAAC GCAGTTTCGT CATACGCCCT TTGGCAGAAA


 


401
TCCTCCCTGA TTTTATTTTG GGAAAATACG GAAAGGTTGT CGAATTGTCA


 


451
AAACGGCTGG GCAATCAAGG CATCCGTCTT TTACCGGACA GGTAA






This corresponds to the amino acid sequence <SEQ ID 50; ORF 008.ng>:










g008.pep




1
MNNRHFAVIA LGSNLDNPAQ QIRGALDALS SHPDIRLEQV SSLYMTAPVG


 


51
YDNQPDFINA VCTVSTTLDG IALLAELNRI EADFGRERSF RNAPRTLDLD


 


101
IIDFDGISSD DPRLTLPHPR AHERSFVIRP LAEILPDFIL GKYGKVVELS


 


151
KRLGNQGIRL LPDR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 51>:










m008.seq




1
ATGAACAACA GACATTTTGC CGTCATCGCC CTGGGCAGTA ATCTTGAAAA


 


51
CCCTGCTCAA CAGGTACGCG CCGCATTGGA CACGCTGTCG TCCCATCCTG


 


101
ACATCCGTCT TAAACAGGCT TCCTCACTGT ATATGACCGC GCCCGTCGGT


 


151
TACGACAATC AGCCCGATTT TGTCAATGCC GTCTGCACCG TTTCCACCAC


 


201
TCTGGACGGC ATTGCCyTGC TTGCCGAACT CAACCGTATC GAGGCTGATT


 


251
TCGGACGCGA ACGCAGCTTC CGCAACGCGC CGCGCACATT GkATTTGGAC


 


301
ATTATCGACT TTGACGGCAT CTCCAGCGAC GACACsCGAC TcACCtTGCC


 


351
GCATCCGCGC GCGCACGAAC GCAGTTTCGT CATCCGCCCT TTGGCAGAAA


 


401
TCCTCCCTGA TTTTGTTTTA GGAAAACACG GAAAGGTTGC CGAATTGTCA


 


451
AAACGGyTGG GCAATCAAGG TATCCGTCTT TTACCGGACA GGTAATT






This corresponds to the amino acid sequence <SEQ ID 52; ORF 008>:










m008.pep




1
MNNRHFAVIA LGSNLENPAQ QVRAALDTLS SHPDIRLKQA SSLYMTAPVG


 


51
YDNQPDFVNA VCTVSTTLDG IALLAELNRI EADFGRERSF RNAPRTLXLD


 


101
IIDFDGISSD DTRLTLPHPR AHERSFVIRP LAEILPDFVL GKHGKVAELS


 


151
KRLGNQGIRL LPDR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 53>:










a008.seq




1
ATGAACAACA GACATTTTGC CGTCATCGCC CTGGGCAGTA ATCTTGAAAA


 


51
CCCTGCCCAA CAGGTACGCG CCGCATTGGA CACGCTGTCG TCCCATCCTG


 


101
ACATCCGTCT TAAACAGGCT TCCTCACTGT ATATGACCGC GCCCGTCGGT


 


151
TACGACAATC AGCCCGATTT CGTCAATGCC GTCTGCACCG TTTCCACCAC


 


201
CTTGGACGGC ATTGCCCTGC TTGCCGAACT CAACCGTATC GAAGCCGATT


 


251
TCGGACGCGA ACGCAGCTTC CGCAACGCGC CGCGCACATT GGATTTGGAC


 


301
ATTATCGACT TTGACGGCAT CTCCAGCGAC GACCCCCGAC TCACCCTGCC


 


351
GCATCCGCGC GCGCACGAAC GCAGTTTCGT CATACGCCCT TTGGCAGAAA


 


401
TCCTCCCTGA TTTTATTTTG GGAAAACACG GAAAGGTTGC CGAATTGTCA


 


451
AAACGGCTGG GCAATCAAGG CATCCGTCTT TTACCGGATA AGTAA






This corresponds to the amino acid sequence <SEQ ID 54; ORF 008.a>:










a008.pep




1
MNNRHFAVIA LGSNLENPAQ QVRAALDTLS SHPDIRLKQA SSLYMTAPVG


 


51
YDNQPDFVNA VCTVSTTLDG IALLAELNRI EADFGRERSF RNAPRTLDLD


 


101
IIDFDGISSD DPRLTLPHPR AHERSFVIRP LAEILPDFIL GKHGKVAELS


 


151
KRLGNQGIRL LPDK*






m008/a008 97.6% identity over a 164 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 008 shows 92.7% identity over a 164 aa overlap with a predicted ORF (ORF008.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 55>:










g009.seq




1
ATGCCCCGCG CTGCCGTAGC CTTTGAGCGT CATCATCACA AAAGCAAAGC


 


51
CGAACAAAAT ACCCATCGCC GCGCCGACGC AGAGATAGCC GAAGGCTTCG


 


101
CGGTTGGAAA TCAGCACACG CAGGCGCGAA ACCAGTCCGT AATGGCGGTA


 


151
CAGCTGCCGC TCGTCGCCTT TTCGGATAAA GTGGTTGTcg cGTTCCAAGC


 


201
TGTTGTTCAG GCGGAAATAC AGGTTTTCGC TGATGGCGGC AAAACGTGGC


 


251
AaaaGCCATA A






This corresponds to the amino acid sequence <SEQ ID 56; ORF 009.ng>:










g009.pep




1
MPRAAVAFER HHHKSKAEQN THRRADAEIA EGFAVGNQHT QARNQSVMAV


 


51
QLPLVAFSDK VVVAFQAVVQ AEIQVFADGG KTWQKP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 57>:










m009.seq




1
ATGCCCCGCG CTGCTGTAGC CTTTGAGCGT CATCATCACA AAAGCAAAGC


 


51
CGAACAAAAT ACCCATCGCC GTGCCGACGC AGAGATAGCC GAAGGCTTCG


 


101
CGGTTGGAAA TCAGCACACG CAGGCGCGCA AGCAGTCCGT AATGGCGGTA


 


151
CAGCTGCCGC CGGTCGCCTT TTCGGATAAA GTGGTTGTCG CGTTCCAAGC


 


201
TGTTGTTCAG GCGGAAATAC AGGTTTTCGC TGATGGCGGC AAAACGTGGC


 


251
AAAAGCCATA A






This corresponds to the amino acid sequence <SEQ ID 58; ORF 009>:










m009.pep




1
MPRAAVAFER HHHKSKAEQN THRRADAEIA EGFAVGNQHT QARKQSVMAV


 


51
QLPPVAFSDK VVVAFQAVVQ AEIQVFADGG KTWQKP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 009 shows 97.7% identity over a 86 aa overlap with a predicted ORF (ORF 009.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 59>:










a009.seq




1
ATGCCCCGCG CTGCTGTAGC CTTTGAGCGT CATCATCACA AAAGCAAAGC


 


51
CGAACAAAAT ACCCATCGCC GTGCCGACGC AGAGATAGCC GAAGGCTTCG


 


101
CGGTTGGAAA TCAGCACACG CAGGCGCGCA AGCAGTCCGT AATGGCGGTC


 


151
CAGCTGCCGC TCGTCGCCTT TTCGGATAAA GTGGTTGTCG CGTTCCAAGC


 


201
TGTTCTTCAG GCGGAAATAC AGGTTTTCGC TGATGGCGGC AAAACGTGGC


 


251
AAAAGCCATA A






This corresponds to the amino acid sequence <SEQ ID 60; ORF 009.a>:










a009.pep




1
MPRAAVAFER HHHKSKAEQN THRRADAEIA EGFAVGNQHT QARKQSVMAV


 


51
QLPLVAFSDK VVVAFQAVLQ AEIQVFADGG KTWQKP*






m009/a009 97.7% identity over a 86 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 61>:










g010.seq




1
ATGGGTTTTC CTGTTCGCAA GTTTGATGCC GTGATTGTCG GCGGTGGCGG


 


51
TGCAGGTTTA CGTGCAGCCC TCCAATTATC CAAATCCGGT TTGAATTGTG


 


101
CCGTTTTGTC TAAAGTGTTC CCGACCCGCT CGCATACCGT AGCGGCGCAG


 


151
GGCGGTATTT CCGCCTCTCT GGGTAATGTG CAGGAGGACC GTTGGGACTG


 


201
GCACATGTAC GATACCGTGA AAGGTTCCGA CTGGCTGGGC GACCAAGATG


 


251
CGATTGAGTT TATGTGTCGC GCTGCGCCTG AAGCGGTGAT TGAGTTGGAA


 


301
CACATGGGTA TGCCTTTTGA CCGCGTTGAA AGCGGCAAAA TTTATCAGCG


 


351
TCCTTTCGGC GGACATACTG CCGAACATGG TAAACGTGCG GTAGAACGTG


 


401
CATGTGCGGT TGCCGACCGT ACCGGTCATG CGATGTTGCA TACTTTGTAC


 


451
CAACAAAACG TCCGTGCCAA TACACAATTC TTTGTGGAAT GGACGGCGCA


 


501
AGATTTGATT CGTGATGAAA ACGGCGATGT CGTCGGCGTA ACCGCCATGG


 


551
AAATGGAAAC GGGCGAAGTT TATATTTTCC ACGCCAAGGC CGTGATGTTT


 


601
GCTACCGGTG GCGGCGGTCG TATTTATGCT TCTTCTACCA ATGCTTATAT


 


651
GAATACCGGT GACGGTTTGG GCATTTGCGC CCGTGCGGGC ATTCCGTTGG


 


701
AAGATATGGA ATTCTGGCAA TTCCACCCGA CCGGCGTGGC GGGTGCGGGC


 


751
GTGTTGATTA CCGAAGGCGT ACGCGGCGAG GGCGGTATTC TGTTGAacgc


 


801
cgacggcgaA cgcTTTATGG AAcgctatgc GCcgACCGta aAagaCTTGG


 


851
CTTCTCGCga cgtGGTTTCA CgcgcGatgG CGatggaAAt ctatgaaggt


 


901
cgcggctgTG GtaaAAAcaA agaCCacgtC TTACTGAAAA TCGACcAtAt


 


951
cggtGCAGAA AAAATTATGG AAAAACTGCC GGGCATCCGC GAGATTTCCA


 


1001
TTCagtttgc cGGTATCGAT CCGATTAAAG ACCCGATTcc ggttgTGCCG


 


1051
ACTACCCACT ATATGATGGG CGGCATTCcg aCCAATTATC ACGGTGAAGT


 


1101
TGTTGTTCCG CAAGGCGACG AGTACGAAGT ACCTGTAAAA GGCCTGTATG


 


1151
CCGCAGGTGA GTGCGCCTGT GCTTCCGTAC ACGGTGCGAA CCGTTTGGGT


 


1201
ACGAACTCCC TGCTGGACTT GGTGGTGTTC cgcccaaccc cccggtga






This corresponds to the amino acid sequence <SEQ ID 62; ORF 010.ng>:










g010.pep




1
MGFPVRKFDA VIVGGGGAGL RAALQLSKSG LNCAVLSKVF PTRSHTVAAQ


 


51
GGISASLGNV QEDRWDWHMY DTVKGSDWLG DQDAIEFMCR AAPEAVIELE


 


101
HMGMPFDRVE SGKIYQRPFG GHTAEHGKRA VERACAVADR TGHAMLHTLY


 


151
QQNVRANTQF FVEWTAQDLI RDENGDVVGV TAMEMETGEV YIFHAKAVMF


 


201
ATGGGGRIYA SSTNAYMNTG DGLGICARAG IPLEDMEFWQ FHPTGVAGAG


 


251
VLITEGVRGE GGILLNADGE RFMERYAPTV KDLASRDVVS RAMAMEIYEG


 


301
RGCGKNKDHV LLKIDHIGAE KIMEKLPGIR EISIQFAGID PIKDPIPVVP


 


351
TTHYMMGGIP TNYHGEVVVP QGDEYEVPVK GLYAAGECAC ASVHGANRLG


 


401
TNSLLDLVVF RPTPR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 63>:









m010.seq (PARTIAL)










1
..nTCCAATTAT CCAAATCCGG TCTGAATTGT GCCGTTTTGT CTAAAGTGTT



 


51
  CCCGACCCGT TCGCATACCG TAGCGGCGCA GGGCGGTATT TCCGCCTCTn


 


101
  TGGGTAATGT GCAGGAAGAC CGTTGGGACT GGCACATGTA CGATACCGTG


 


151
  AAAGGTTCCG ACTGGTTGGG CGACCAAGAT GCGATTGAGT TTATGTGCCG


 


201
  CGCCGCGCCT GAAGCCGTAA TTGAGTTGGA ACACATGGGT ATGCCTTTTG


 


251
  ACCGTGTGGA AAGCGGTAAA ATTTATCAGC GTCCTTTCGG CGGCCATACT


 


301
  GCCGAACACG GTAAACGCGC GGTAGAACGC GyCTGTGCGG TTGCCGACCG


 


351
  TACAGGTCAT GCGATGCTGC ATACTTTGTA CCAACAAAAC GTCCGTGCCA


 


401
  ATACGCAATT CTTTGTGGAA TGGACGGCAC AAGATTTGAT TCGTGATGAA


 


451
  AACGGCGATG TCGTCGGCGT AACCGCCATG GAAATGGAAA CCGGCGAAgT


 


501
  TTATATTTTC CACGCTAAAG CTGTGATGTT TGCTACCGGC GGCGGCGGTC


 


551
  GTATTTATGC GTCTTCTACC AATGCCTATA TGAATACCGG CGATGGTTTG


 


601
  GGTATTTGTG CGCGTGCAGG TATCCCGTTG GAAGACATGG AATTCTGGCA


 


651
  ATTCCAGCCG ACCGGCGTGG CGGGTGCGGG CGTGTTGATT ACCGAA....






This corresponds to the amino acid sequence <SEQ ID 64; ORF 010>:









m010.pep (PARTIAL)










1
..XQLSKSGLNC AVLSKVFPTR SHTVAAQGGI SASXGNVQED RWDWHMYDTV



 


51
  KGSDWLGDQD AIEFMCRAAP EAVIELEHMG MPFDRVESGK IYQRPFGGHT


 


101
  AEHGKRAVER XCAVADRTGH AMLHTLYQQN VRANTQFFVE WTAQDLIRDE


 


151
  NGDVVGVTAM EMETGEVYIF HAKAVMFATG GGGRIYASST NAYMNTGDGL


 


201
  GICARAGIPL EDMEFWQFQP TGVAGAGVLI TE...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 65>:










a010.seq




1
ATGGGCTTTC CTGTTCGCAA GTTTGATGCC GTGATTGTCG GCGGTGGTGG


 


51
TGCAGGTTTA CGCGCANCCC TCCAATTATC CAAATCCGGT CTGAATTGTG


 


101
CCGTTTTGTC TAAAGTGTTC CCGACCCGTT CGCATACCGT AGCGGCGCAG


 


151
GGCGGTATTT CCGCCTCTCT GGGTAATGTG CAGGAAGACC GTTGGGACTG


 


201
GCACATGTAC GATACCGTGA AAGGTTCCGA CTGGTTGGGC GACCAAGATG


 


251
CGATTGAGTT TATGTGCCGC GCCGCGCCTG AAGCCGTAAT TGAGTTGGAA


 


301
CACATGGGTA TGCCTTTTGA CCGTGTGGAA AGCGGTAAAA TTTATCAGCG


 


351
TCCTTTCGGC GGCCATACTG CCGAACACGG TAAACGCGCG GTAGAACGCG


 


401
CCTGTGCNGT TGCCGACCGT ACAGGTCATG CGATGCTGCA TACTTTGTAC


 


451
CAACAAAATG TCCGTGCCAA TACGCAATTC TTTGTGGAAT GGACGGCACA


 


501
AGATTTGATT CGTGATGAAA ACGGCGATGT CGTCGGCGTA ACCGCCATGG


 


551
AAATGGAAAC CGGCGAAGTT TATATTTTCC ACGCTAAAGC TGTGATGTTT


 


601
GCTACCGGCG GCGGCGGCCG TATTTATGCG TCTTCTACCA ATGCCTATAT


 


651
GAATACCGGC GATGGTTTGG GTATTTGTGC GCGTGCAGGT ATCCCGTTGG


 


701
AAGACATGGA ATTCTGGCAA TTCCACCCGA CCGGCGTGGC AGGTGCGGGC


 


751
GTGTTGATTA CCGAAGGCGT ACGCGGCGAG GGCGGTATTC TGTTGAATGC


 


801
CGACGGCGAA CGCTTTATGG AACGCTATGC GCCGACCGTA AAAGACTTGG


 


851
CTTCTCGCGA CGTTGTTTCC CGCGCGATGG CGATGGAAAT CTACGAAGGT


 


901
CGCGGCTGCG GTAAAAACAA AGACCATGTC TTACTGAAAA TCGACCATAT


 


951
CGGCGCAGAA AAAATTATGG AAAAACTGCC GGGCATCCGC GAGATTTCCA


 


1001
TTCAGTTCGC CGGTATCGAT CCGATTAAAG ACCCGATTCC CGTTGTGCCG


 


1051
ACTACCCACT ATATGATGGG CGGTATTCCG ACCAACTACC ATGGCGAAGT


 


1101
TGTCGTTCCT CAAGGCGACG AATACGAAGT GCCTGTAAAA GGTCTGTATG


 


1151
CGGCAGGTGA GTGCGCCTGT GCTTCCGTAC ACGGTGCGAA CCGCTTGGGT


 


1201
ACGAACTCCC TGCTGGACTT AGTGGTATTC GGTAAAGCTG CCGGCGACAG


 


1251
CATGATTAAA TTCATCAAAG AGCAAAGCGA CTGGAAACCT TTGCCTGCTA


 


1301
ATGCCGGCGA ACTGACCCGC CAACGTATCG AGCGTTTGGA CAATCAAACT


 


1351
GATGGTGAAA ACGTTGATGC ATTGCGCCGC GAACTGCAAC GCTCCGTACA


 


1401
ATTGCACGCC GGCGTGTTCC GTACTGATGA GATTCTGAGC AAAGGCGTTC


 


1451
GAGAAGTCAT GGCGATTGCC GAGCGTGTGA AACGTACCGA AATCAAAGAC


 


1501
AAGAGCAAAG TGTGGAATAC CGCGCGTATC GAGGCTTTGG AATTGGATAA


 


1551
CCTAATTGAA GTGGCGAAAG CGACTTTGGT GTCTGCCGAA GCACGTAAAG


 


1601
AATCACGCGG TGCGCACGCT TCAGACGACC ATCCTGAGCG CGATGATGAA


 


1651
AACTGGATGA AACATACGCT GTACCATTCA GATGCCAATA CCTTGTCCTA


 


1701
CAAACCGGTG CACACCAAGC CTTTGAGCGT GGAATACATC AAACCGGCCA


 


1751
AGCGCGTTTA TTGA






This corresponds to the amino acid sequence <SEQ ID 66; ORF 010.a>:










a010.pep




1
MGFPVRKFDA VIVGGGGAGL RAXLQLSKSG LNCAVLSKVF PTRSHTVAAQ


 


51
GGISASLGNV QEDRWDWHMY DTVKGSDWLG DQDAIEFMCR AAPEAVIELE


 


101
HMGMPFDRVE SGKIYQRPFG GHTAEHGKRA VERACAVADR TGHAMLHTLY


 


151
QQNVRANTQF FVEWTAQDLI RDENGDVVGV TAMEMETGEV YIFHAKAVMF


 


201
ATGGGGRIYA SSTNAYMNTG DGLGICARAG IPLEDMEFWQ FHPTGVAGAG


 


251
VLITEGVRGE GGILLNADGE RFMERYAPTV KDLASRDVVS RAMAMEIYEG


 


301
RGCGKNKDHV LLKIDHIGAE KIMEKLPGIR EISIQFAGID PIKDPIPVVP


 


351
TTHYMMGGIP TNYHGEVVVP QGDEYEVPVK GLYAAGECAC ASVHGANRLG


 


401
TNSLLDLVVF GKAAGDSMIK FIKEQSDWKP LPANAGELTR QRIERLDNQT


 


451
DGENVDALRR ELQRSVQLHA GVFRTDEILS KGVREVMAIA ERVKRTEIKD


 


501
KSKVWNTARI EALELDNLIE VAKATLVSAE ARKESRGAHA SDDHPERDDE


 


551
NWMKHTLYHS DANTLSYKPV HTKPLSVEYI KPAKRVY*






m010/a010 98.7% identity over a 231 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 010 shows 98.7% identity over a 231 aa overlap with a predicted ORF (ORF 010.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 67>:










g010-1.seq..




1
ATGGGTTTTC CTGTTCGCAA GTTTGATGCC GTGATTGTCG GCGGTGGCGG


 


51
TGCAGGTTTA CGTGCAGCCC TCCAATTATC CAAATCCGGT TTGAATTGTG


 


101
CCGTTTTGTC TAAAGTGTTC CCGACCCGCT CGCATACCGT AGCGGCGCAG


 


151
GGCGGTATTT CCGCCTCTCT GGGTAATGTG CAGGAGGACC GTTGGGACTG


 


201
GCACATGTAC GATACCGTGA AAGGTTCCGA CTGGCTGGGC GACCAAGATG


 


251
CGATTGAGTT TATGTGTCGC GCTGCGCCTG AAGCGGTGAT TGAGTTGGAA


 


301
CACATGGGTA TGCCTTTTGA CCGCGTTGAA AGCGGCAAAA TTTATCAGCG


 


351
TCCTTTCGGC GGACATACTG CCGAACATGG TAAACGTGCG GTAGAACGTG


 


401
CATGTGCGGT TGCCGACCGT ACCGGTCATG CGATGTTGCA TACTTTGTAC


 


451
CAACAAAACG TCCGTGCCAA TACACAATTC TTTGTGGAAT GGACGGCGCA


 


501
AGATTTGATT CGTGATGAAA ACGGCGATGT CGTCGGCGTA ACCGCCATGG


 


551
AAATGGAAAC GGGCGAAGTT TATATTTTCC ACGCCAAGGC CGTGATGTTT


 


601
GCTACCGGTG GCGGCGGTCG TATTTATGCT TCTTCTACCA ATGCTTATAT


 


651
GAATACCGGT GACGGTTTGG GCATTTGCGC CCGTGCGGGC ATTCCGTTGG


 


701
AAGATATGGA ATTCTGGCAA TTCCACCCGA CCGGCGTGGC GGGTGCGGGC


 


751
GTGTTGATTA CCGAAGGCGT ACGCGGCGAG GGCGGTATTC TGTTGAACGC


 


801
CGACGGCGAA CGCTTTATGG AACGCTATGC GCCGACCGTA AAAGACTTGG


 


851
CTTCTCGCGA CGTGGTTTCA CGCGCGATGG CGATGGAAAT CTATGAAGGT


 


901
CGCGGCTGTG GTAAAAACAA AGACCACGTC TTACTGAAAA TCGACCATAT


 


951
CGGTGCAGAA AAAATTATGG AAAAACTGCC GGGCATCCGC GAGATTTCCA


 


1001
TTCAGTTTGC CGGTATCGAT CCGATTAAAG ACCCGATTCC GGTTGTGCCG


 


1051
ACTACCCACT ATATGATGGG CGGCATTCCG ACCAATTATC ACGGTGAAGT


 


1101
TGTTGTTCCG CAAGGCGACG AGTACGAAGT ACCTGTAAAA GGCCTGTATG


 


1151
CCGCAGGTGA GTGCGCCTGT GCTTCCGTAC ACGGTGCGAA CCGTTTGGGT


 


1201
ACGAACTCCC TGCTGGACTT GGTGGTGTTC cgcccaaccc cccggtga






This corresponds to the amino acid sequence <SEQ ID 68; ORF 010-1.ng>:










g010-1.pep




1
MGFPVRKFDA VIVGGGGAGL RAALQLSKSG LNCAVLSKVF PTRSHTVAAQ


 


51
GGISASLGNV QEDRWDWHMY DTVKGSDWLG DQDAIEFMCR AAPEAVIELE


 


101
HMGMPFDRVE SGKIYQRPFG GHTAEHGKRA VERACAVADR TGHAMLHTLY


 


151
QQNVRANTQF FVEWTAQDLI RDENGDVVGV TAMEMETGEV YIFHAKAVMF


 


201
ATGGGGRIYA SSTNAYMNTG DGLGICARAG IPLEDMEFWQ FHPTGVAGAG


 


251
VLITEGVRGE GGILLNADGE RFMERYAPTV KDLASRDVVS RAMAMEIYEG


 


301
RGCGKNKDHV LLKIDHIGAE KIMEKLPGIR EISIQFAGID PIKDPIPVVP


 


351
TTHYMMGGIP TNYHGEVVVP QGDEYEVPVK GLYAAGECAC ASVHGANRLG


 


401
TNSLLDLVVF RPTPR*






g010-1/P10444









sp|P10444|DHSA_ECOLI SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT



gnl|PID|d1015210 (D90711) Succinate dehydrogenase, flavoprotein


[Escherichia coli] gi|1786942 (AE000175) succinate dehydrogenase


flavoprotein subunit [Escherichia coli] Length = 588


Score = 1073 (495.6 bits), Expect = 6.7e−169, Sum P(2) = 6.7e−169


Identities = 191/303 (63%), Positives = 238/303 (78%)











Query:
1
MGFPVRKFDAVIVXXXXXXXXXXXXXSKSGLNCAVLSKVFPTRSHTVAAQGGISASLGNV
60





M  PVR+FDAV++             S+SG  CA+LSKVFPTRSHTV+AQGGI+ +LGN


Sbjct:
1
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNT
60


 


Query:
61
QEDRWDWHMYDTVKGSDWLGDQDAIEFMCRAAPEAVIELEHMGMPFDRVESGKIYQRPFG
120




 ED W+WHMYDTVKGSD++GDQDAIE+MC+  PEA++ELEHMG+PF R++ G+IYQRPFG


Sbjct:
61
HEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFG
120


 


Query:
121
GHTAEHGKRAVERACAVADRTGHAMLHTLYQQNVRANTQFFVEWTAQDLIRDENGDVVGV
180




G +   G     R  A ADRTGHA+LHTLYQQN++ +T  F EW A DL+++++G VVG


Sbjct:
121
GQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGC
180


 


Query:
181
TAMEMETGEVYIFHAKAVMFATGGGGRIYASSTNAYMNTGDGLGICARAGIPLEDMEFWQ
240




TA+ +ETGEV  F A+A + ATGG GRIY S+TNA++NTGDG+G+  RAG+P++DME WQ


Sbjct:
181
TALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQ
240


 


Query:
241
FHPTGVAGAGVLITEGVRGEGGILLNADGERFMERYAPTVKDLASRDVVSRAMAMEIYEG
300




FHPTG+AGAGVL+TEG RGEGG LLN  GERFMERYAP  KDLA RDVV+R++ +EI EG


Sbjct:
241
FHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREG
300


 


Query:
301
RGC
303




RGC


Sbjct:
301
RGC
303


 








Score = 249 (115.0 bits), Expect = 6.7e−169, Sum P(2) = 6.7e−169



Identities = 53/102 (51%), Positives = 62/102 (60%)











Query:
309
HVLLKIDHIGAEKIMEKLPGIREISIQFAGXXXXXXXXXXXXTTHYMMGGIPTNYHGEVV
368





H  LK+DH+G E +  +LPGI E+S  FA             T HYMMGGIPT   G+ +


Sbjct:
310
HAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQAL
369


 


Query:
369
VPQGDEYEVPVKGLYAAGECACASVHGANRLGTNSLLDLVVF
410




       +V V GL+A GE AC SVHGANRLG NSLLDLVVF


Sbjct:
370
TVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVF
411






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 69>:










m010-1.seq..




1
ATGGGTTTTC CTGTTCGCAA GTTTGATGCC GTGATTGTCG GCGGTGGTGG


 


51
TGCAGGTTTA CGCGCAGCCC TCCAATTATC CAAATCCGGT CTGAATTGTG


 


101
CCGTTTTGTC TAAAGTGTTC CCGACCCGTT CGCATACCGT AGCGGCGCAg


 


151
GGCGGTATTT CCGCCTCTCT GGGTAATGTG CAGGAAGACC GTTGGGACTG


 


201
GCACATGTAC GATACCGTGA AAGGTTCCGA CTGGTTGGGC GACCAAGATG


 


251
CGATTGAGTT TATGTGCCGC GCCGCGCCTG AAGCCGTAAT TGAGTTGGAA


 


301
CACATGGGTA TGCCTTTTGA CCGTGTGGAA AGCGGTAAAA TTTATCAGCG


 


351
TCCTTTCGGC GGCCATACTG CCGAACACGG TAAACGCGCG GTAGAACGCG


 


401
CCTGTGCGGT TGCCGACCGT ACAGGTCATG CGATGCTGCA TACTTTGTAC


 


451
CAACAAAACG TCCGTGCCAA TACGCAATTC TTTGTGGAAT GGACGGCACA


 


501
AGATTTGATT CGTGATGAAA ACGGCGATGT CGTCGGCGTA ACCGCCATGG


 


551
AAATGGAAAC CGGCGAAGTT TATATTTTCC ACGCTAAAGC TGTGATGTTT


 


601
GCTACCGGCG GCGGCGGTCG TATTTATGCG TCTTCTACCA ATGCCTATAT


 


651
GAATACCGGC GATGGTTTGG GTATTTGTGC GCGTGCAGGT ATCCCGTTGG


 


701
AAGACATGGA ATTCTGGCAA TTCCACCCGA CCGGCGTGGC GGGTGCGGGC


 


751
GTGTTGATTA CCGAAGGCGT ACGCGGCGAG GGCGGTATTC TGTTGAATGC


 


801
CGACGGCGAA CGCTTTATGG AACGCTATGC GCCGACCGTA AAAGACTTGG


 


851
CTTCTCGCGA CGTTGTTTCC CGCGCGATGG CGATGGAAAT CTACGAAGGT


 


901
CGCGGCTGCG GTAAAAACAA AGACCATGTC TTACTGAAAA TCGACCATAT


 


951
CGGCGCAGAA AAAATTATGG AAAAACTGCC GGGCATCCGC GAGATTTCCA


 


1001
TTCAGTTCGC CGGTATCGAT CCGATTAAAG ACCCGATTCC CGTTGTGCCG


 


1051
ACTACCCACT ATATGATGGG CGGCATTCCG ACCAATTACC ACGGCGAAGT


 


1101
TGTCGTTCCG CAAGGTGAAG ATTACGAAGT GCCTGTAAAA GGTCTGTATG


 


1151
CGGCAGGTGA GTGCGCTTGT GCTTCCGTAC ACGGTGCGAA CCGCTTGGGT


 


1201
ACCAACTCCC TGTTGGACTT GGTGGTATTC GGTAAAGCTG CCGGCGACAG


 


1251
CATGATTAAA TTCATCAAAG AGCAAAGCGA CTGGAAACCT TTGCCTGCTA


 


1301
ATGCAGGTGA GTTGACCCGC CAACGTATCG AGCGTTTGGA CAACCAAACC


 


1351
GATGGTGAAA ACGTTGATGC ATTGCGTCGC GAACTGCAAC GCTCTGTACA


 


1401
ACTGCACGCC GGCGTGTTCC GTACTGATGA GATTCTGAGC AAAGGCGTTC


 


1451
GAGAAGTCAT GGCGATTGCC GAGCGTGTGA AACGTACCGA AATCAAAGAC


 


1501
AAGAGCAAAG TGTGGAATAC CGCGCGTATC GAGGCTTTGG AATTGGATAA


 


1551
CCTGATTGAA GTGGCGAAAG CGACTTTGGT GTCTGCCGAA GCACGTAAAG


 


1601
AATCACGCGG TGCGCACGCT TCAGACGACC ATCCTGAGCG CGATGATGAA


 


1651
AACTGGATGA AACATACGCT GTACCATTCA GATATCAATA CCTTGTCCTA


 


1701
CAAACCGGTG CACACCAAGC CTTTGAGCGT GGAATACATC AAACCGGCCA


 


1751
AGCGCGTTTA TTGATGA






This corresponds to the amino acid sequence <SEQ ID 70; ORF 010-1>:










m010-1.pep..




1
MGFPVRKFDA VIVGGGGAGL RAALQLSKSG LNCAVLSKVF PTRSHTVAAQ


 


51
GGISASLGNV QEDRWDWHMY DTVKGSDWLG DQDAIEFMCR AAPEAVIELE


 


101
HMGMPFDRVE SGKIYQRPFG GHTAEHGKRA VERACAVADR TGHAMLHTLY


 


151
QQNVRANTQF FVEWTAQDLI RDENGDVVGV TAMEMETGEV YIFHAKAVMF


 


201
ATGGGGRIYA SSTNAYMNTG DGLGICARAG IPLEDMEFWQ FHPTGVAGAG


 


251
VLITEGVRGE GGILLNADGE RFMERYAPTV KDLASRDVVS RAMAMEIYEG


 


301
RGCGKNKDHV LLKIDHIGAE KIMEKLPGIR EISIQFAGID PIKDPIPVVP


 


351
TTHYMMGGIP TNYHGEVVVP QGEDYEVPVK GLYAAGECAC ASVHGANRLG


 


401
TNSLLDLVVF GKAAGDSMIK FIKEQSDWKP LPANAGELTR QRIERLDNQT


 


451
DGENVDALRR ELQRSVQLHA GVFRTDEILS KGVREVMAIA ERVKRTEIKD


 


501
KSKVWNTARI EALELDNLIE VAKATLVSAE ARKESRGAHA SDDHPERDDE


 


551
NWMKHTLYHS DINTLSYKPV HTKPLSVEYI KPAKRVY*






m010-1/g010-199.5% identity in 410 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 71>:










a010-1.seq..




1
ATGGGCTTTC CTGTTCGCAA GTTTGATGCC GTGATTGTCG GCGGTGGTGG


 


51
TGCAGGTTTA CGCGCANCCC TCCAATTATC CAAATCCGGT CTGAATTGTG


 


101
CCGTTTTGTC TAAAGTGTTC CCGACCCGTT CGCATACCGT AGCGGCGCAG


 


151
GGCGGTATTT CCGCCTCTCT GGGTAATGTG CAGGAAGACC GTTGGGACTG


 


201
GCACATGTAC GATACCGTGA AAGGTTCCGA CTGGTTGGGC GACCAAGATG


 


251
CGATTGAGTT TATGTGCCGC GCCGCGCCTG AAGCCGTAAT TGAGTTGGAA


 


301
CACATGGGTA TGCCTTTTGA CCGTGTGGAA AGCGGTAAAA TTTATCAGCG


 


351
TCCTTTCGGC GGCCATACTG CCGAACACGG TAAACGCGCG GTAGAACGCG


 


401
CCTGTGCNGT TGCCGACCGT ACAGGTCATG CGATGCTGCA TACTTTGTAC


 


451
CAACAAAATG TCCGTGCCAA TACGCAATTC TTTGTGGAAT GGACGGCACA


 


501
AGATTTGATT CGTGATGAAA ACGGCGATGT CGTCGGCGTA ACCGCCATGG


 


551
AAATGGAAAC CGGCGAAGTT TATATTTTCC ACGCTAAAGC TGTGATGTTT


 


601
GCTACCGGCG GCGGCGGCCG TATTTATGCG TCTTCTACCA ATGCCTATAT


 


651
GAATACCGGC GATGGTTTGG GTATTTGTGC GCGTGCAGGT ATCCCGTTGG


 


701
AAGACATGGA ATTCTGGCAA TTCCACCCGA CCGGCGTGGC AGGTGCGGGC


 


751
GTGTTGATTA CCGAAGGCGT ACGCGGCGAG GGCGGTATTC TGTTGAATGC


 


801
CGACGGCGAA CGCTTTATGG AACGCTATGC GCCGACCGTA AAAGACTTGG


 


851
CTTCTCGCGA CGTTGTTTCC CGCGCGATGG CGATGGAAAT CTACGAAGGT


 


901
CGCGGCTGCG GTAAAAACAA AGACCATGTC TTACTGAAAA TCGACCATAT


 


951
CGGCGCAGAA AAAATTATGG AAAAACTGCC GGGCATCCGC GAGATTTCCA


 


1001
TTCAGTTCGC CGGTATCGAT CCGATTAAAG ACCCGATTCC CGTTGTGCCG


 


1051
ACTACCCACT ATATGATGGG CGGTATTCCG ACCAACTACC ATGGCGAAGT


 


1101
TGTCGTTCCT CAAGGCGACG AATACGAAGT GCCTGTAAAA GGTCTGTATG


 


1151
CGGCAGGTGA GTGCGCCTGT GCTTCCGTAC ACGGTGCGAA CCGCTTGGGT


 


1201
ACGAACTCCC TGCTGGACTT AGTGGTATTC GGTAAAGCTG CCGGCGACAG


 


1251
CATGATTAAA TTCATCAAAG AGCAAAGCGA CTGGAAACCT TTGCCTGCTA


 


1301
ATGCCGGCGA ACTGACCCGC CAACGTATCG AGCGTTTGGA CAATCAAACT


 


1351
GATGGTGAAA ACGTTGATGC ATTGCGCCGC GAACTGCAAC GCTCCGTACA


 


1401
ATTGCACGCC GGCGTGTTCC GTACTGATGA GATTCTGAGC AAAGGCGTTC


 


1451
GAGAAGTCAT GGCGATTGCC GAGCGTGTGA AACGTACCGA AATCAAAGAC


 


1501
AAGAGCAAAG TGTGGAATAC CGCGCGTATC GAGGCTTTGG AATTGGATAA


 


1551
CCTAATTGAA GTGGCGAAAG CGACTTTGGT GTCTGCCGAA GCACGTAAAG


 


1601
AATCACGCGG TGCGCACGCT TCAGACGACC ATCCTGAGCG CGATGATGAA


 


1651
AACTGGATGA AACATACGCT GTACCATTCA GATGCCAATA CCTTGTCCTA


 


1701
CAAACCGGTG CACACCAAGC CTTTGAGCGT GGAATACATC AAACCGGCCA


 


1751
AGCGCGTTTA TTGA






This corresponds to the amino acid sequence <SEQ ID 72; ORF 010-1.a>:










a010-1.pep..




1
MGFPVRKFDA VIVGGGGAGL RAXLQLSKSG LNCAVLSKVF PTRSHTVAAQ


 


51
GGISASLGNV QEDRWDWHMY DTVKGSDWLG DQDAIEFMCR AAPEAVIELE


 


101
HMGMPFDRVE SGKIYQRPFG GHTAEHGKRA VERACAVADR TGHAMLHTLY


 


151
QQNVRANTQF FVEWTAQDLI RDENGDVVGV TAMEMETGEV YIFHAKAVMF


 


201
ATGGGGRIYA SSTNAYMNTG DGLGICARAG IPLEDMEFWQ FHPTGVAGAG


 


251
VLITEGVRGE GGILLNADGE RFMERYAPTV KDLASRDVVS RAMAMEIYEG


 


301
RGCGKNKDHV LLKIDHIGAE KIMEKLPGIR EISIQFAGID PIKDPIPVVP


 


351
TTHYMMGGIP TNYHGEVVVP QGDEYEVPVK GLYAAGECAC ASVHGANRLG


 


401
TNSLLDLVVF GKAAGDSMIK FIKEQSDWKP LPANAGELTR QRIERLDNQT


 


451
DGENVDALRR ELQRSVQLHA GVFRTDEILS KGVREVMAIA ERVKRTEIKD


 


501
KSKVWNTARI EALELDNLIE VAKATLVSAE ARKESRGAHA SDDHPERDDE


 


551
NWMKHTLYHS DANTLSYKPV HTKPLSVEYI KPAKRVY*






m010-1/a010-199.3% identity in 587 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 73>:










g011.seq




1
ATGAAGACAC ACCGCAAGAC CTGCTCTGCG GTGTGTTTTG CTTTTCAGAC


 


51
GGCATCGAAA CCCGCCGTTT CCATCCGACA TCCCAGCGAG GACATCATGA


 


101
GCCTGAAAAC CCGCCTTACC GAAGATATGA AAACCGCGAT GCGCGCCAAA


 


151
GATCAAGTTT CCCTCGGCAC CATCCGCCTC ATCAATGCCG CCGTCAAACA


 


201
GTTTGAAGTA GACGAACGCA CCGAAGCCGA CGATGCCAAA ATCACCGCCA


 


251
TCCTGACCAA AATGGTCAAA CAGCGCAAAG ACGGCGCGAA AATCTACACT


 


301
GAAGCCGGCC GTCAGGATTT GGCAGACAAA GAAAACGCCG AAATCGACGT


 


351
GCTGCACCGC TACCTGCCGC AAATGCTCTC CGCCGGCGAA ATCCGCACCG


 


401
CCGTCGAAGC AGCCGTTGCC GAAACCGGCG CGGCAGGTAT GGCGGATATG


 


451
GGCAAAGTGA TGGTCGTATT GAAAAcccGC CTCGCCGGCA AAGccgATAT


 


501
GGGCGAAGTC AACAAAATCT TGAAAAccGt aCTGACCGCC tga






This corresponds to the amino acid sequence <SEQ ID 74; ORF 011.ng>:










g011.pep




1
MKTHRKTCSA VCFAFQTASK PAVSIRHPSE DIMSLKTRLT EDMKTAMRAK


 


51
DQVSLGTIRL INAAVKQFEV DERTEADDAK ITAILTKMVK QRKDGAKIYT


 


101
EAGRQDLADK ENAEIDVLHR YLPQMLSAGE IRTAVEAAVA ETGAAGMADM


 


151
GKVMVVLKTR LAGKADMGEV NKILKTVLTA *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 75>:









m011.seq (partial)










1
ATGAGGACAC ACCGCAAGAC CTGCTCTGCG GTGTGTTTTG CTTTTCAGAC



 


51
GGCATCGAAA CCCGCCGTTT CCATCCGACA TCCCAGCGAG GACATCATGA


 


101
GCCTGAAAAT CCGCCTTACC GAAGACATGA AAACCGCGAT GCGCGCCAAA


 


151
GACCAAGTTT CCCTCGGCAC CATCCGCCTC ATCAACGCCG CCGTCAAACA


 


201
GTTTGAAGTG GACGAACGCA CCGAAGCCGA CGATGCCAAA ATCACCGCCA


 


251
TCCTGACCAA AATGGTCAAA CAGCGAAAAG ACAGCGCGAA AATCTACACT


 


301
GAAGCCGGCC GTCAGGATTT GGCAGACAAA GAAAACGCCG AAATCGAGGT


 


351
ACTGCACCGC TACCTTCCCC AAATGCTTTC CGCCGGCGAA ATCCGTACCG


 


401
AGGTCGAAGC TGCCGTTGCC GAAACCGGCG CGGCAGGTAT GGCGGATATG


 


451
GGTAAAGTCA TGGGGCTGCT GAAAACCCGC CTCGCAGGTA AAGCCGA...






This corresponds to the amino acid sequence <SEQ ID 76; ORF 011>:









m011.pep (partial)










1
MRTHRKTCSA VCFAFQTASK PAVSIRHPSE DIMSLKIRLT EDMKTAMRAK



 


51
DQVSLGTIRL INAAVKQFEV DERTEADDAK ITAILTKMVK QRKDSAKIYT


 


101
EAGRQDLADK ENAEIEVLHR YLPQMLSAGE IRTEVEAAVA ETGAAGMADM


 


151
GKVMGLLKTR LAGKA.....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 011 shows 95.8% identity over a 165 aa overlap with a predicted ORF (ORF 011.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 77>:










g012.seq




1
ATGCTCGCCC GTCGCTATTT TTTCAATATC CAACCCGGGG CGGTTTTCAC


 


51
TGACAAACTG CTTGAACAAC TGATGCGTTT CCTCCAGTTC CTGCCGGAAT


 


101
TTCTGTTTGC CCTTTTCCGT ATTTTCACCC ATAAAAGTAA CCGTGCGCTT


 


151
AAATTCGCCC GCCGTCATCA CATCCACATC AATATCATGT TTTTTCAACa


 


201
gGcggTGGAT ATTCGgcact tccgCcacca cacccaccga accgatgacc


 


251
gcaaacggaG CGGAAACAAT TTTATCCGCc acacacgcca tcatatagcc


 


301
gcCGCTTGCC GCGACCTTAT CGAcggcgac ggTCAGCGGA ATATTGCGTT


 


351
CGCGCAAACG CCTAAGCTGC GAAGCCGCCA AACCGTAACC GTGAACCACG


 


401
CCGCCCGGAC TTTCCAATCT GAGCAGAACC TCATCTTCAG GCTTGGCAAT


 


451
CAAAAGCACC GCCGTAATCT CATGACGCAA GGATTCTACG GCGTGTGCAT


 


501
ACAAATCGCC GTCAAAATCC AACACAAAAA GGCGGGATTT TTGCGTTTCG


 


551
GCAGATTTCT CCCCGCCCTC CTTCAAACGC TTTTTCTCTG CTTTGGCTTC


 


601
CGCCTTTTCC TTTTTCTTTT CTTTTTTTTC CTGATGTTTT GTCTCTTCCT


 


651
CGCTTAA






This corresponds to the amino acid sequence <SEQ ID 78; ORF 012.ng>:










g012.pep




1
MLARRYFFNI QPGAVFTDKL LEQLMRFLQF LPEFLFALFR IFTHKSNRAL


 


51
KFARRHHIHI NIMFFQQAVD IRHFRHHTHR TDDRKRSGNN FIRHTRHHIA


 


101
AACRDLIDGD GQRNIAFAQT PKLRSRQTVT VNHAARTFQS EQNLIFRLGN


 


151
QKHRRNLMTQ GFYGVCIQIA VKIQHKKAGF LRFGRFLPAL LQTLFLCFGF


 


201
RLFLFLFFFF LMFCLFLA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 79>:










m012.seq




1
ATGCTCGCCC GTTGCCACTT CCTCAATATC CAATTGAGGG CGGTTCTCGC


 


51
TGACAAACTG CTTGAACAAC TGATGCGTTT CCTCCAGTTC CTGTCGGAAT


 


101
TTCTGTTTGC CCTTTTCCGT ATTTTCACCC ATAAAAGTAA CCGTGCGCTT


 


151
AAATTCGCCC GCCGTCATCA CATCCACATC AATATCATGT TTTTTCAACA


 


201
GGCGGTGGAT ATTCGGTACT TCCGCCACCA CACCCACCGA ACCGACAATC


 


251
GCAAACGGAG CGGAAGCAAT TTTATCCGCC ACACACGCCA TCATATAACC


 


301
GCCGCTCGCn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


351
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


401
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


451
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


501
nnnnnnnnnn nnnnnnnnnC AACACAAAAA GGCGTGATTT nTGCGTTTCG


 


551
GCAGATTTCT CCCCACCCTC CTTCAAACGT TTTTCcTCTG CTTTGGCTTC


 


601
CGCCTTTTCC TTTTTCTTTT CCTCTTTTTC CTGATGTTGT GCCTCTTCCC


 


651
CGCTTAA






This corresponds to the amino acid sequence <SEQ ID 80; ORF 012>:










m012.pep




1
MLARCHFLNI QLRAVLADKL LEQLMRFLQF LSEFLFALFR IFTHKSNRAL


 


51
KFARRHHIHI NIMFFQQAVD IRYFRHHTHR TDNRKRSGSN FIRHTRHHIT


 


101
AARXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX


 


151
XXXXXXXXXX XXXXXXXXXX XXXQHKKA*F XRFGRFLPTL LQTFFLCFGF


 


201
RLFLFLFLFF LMLCLFPA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 81>:










a012.seq




1
ATGCTCGCCC GTTGCCACTT CCTCAATATC CAATTGAGGG CGGTTCTCGC


 


51
TGACAAACTG CTTGAACAAC TGATGCGTTT CCTCCAGTTC CTGTCGGAAT


 


101
TTCTGTTTGC CCTTTTCCGT ATTTTCACCC ATAAAAGTAA CCGTGCGCTT


 


151
AAATTCGCCC GCCGTCATCA CATCCACATC AATATCATGT TTTTTCAACA


 


201
GGCGGTGGAT ATTCGGTACT TCCGCTACAA CACCCACCGA ACCGACAATC


 


251
GCAAACGGAG CGGAAACAAT TTTATCCGCC ACACACGCCA TCATATAACC


 


301
ACCGCTCGCC GCCACCTTAT CGACGGCGAC GGTCAGCGGA ATATTGCGTT


 


351
CGCGCAAACG CCTAAGCTGC GAAGCCGCCA AACCGTAACC GTGAACCACG


 


401
CCGCCCGGAC TTTCCAATCT AAGCAGAACC TCATCTTCAG GCTTGGCAAT


 


451
CAAAAGCACC GCCGTAATCT CATGACGCAA GGATTCTACG GCGTGTGCAT


 


501
ACAAATCGCC GTCAAAATCC AACACAAAAA GGCGGGATTT TTGCGTTTCG


 


551
GAAGATTTCT CCCCACCCTC CTTCAAACGC TTTTTCTCTG CTTTGGCTTC


 


601
CGCCTTTTCC TTTTTCTTTT CCTCTTTTTC CTGATGTTTT GCCTCTTCCC


 


651
CGCTTAA






This corresponds to the amino acid sequence <SEQ ID 82; ORF 012.a>:










a012.pep




1
MLARCHFLNI QLRAVLADKL LEQLMRFLQF LSEFLFALFR IFTHKSNRAL


 


51
KFARRHHIHI NIMFFQQAVD IRYFRYNTHR TDNRKRSGNN FIRHTRHHIT


 


101
TARRHLIDGD GQRNIAFAQT PKLRSRQTVT VNHAARTFQS KQNLIFRLGN


 


151
QKHRRNLMTQ GFYGVCIQIA VKIQHKKAGF LRFGRFLPTL LQTLFLCFGF


 


201
RLFLFLFLFF LMFCLFPA*






m012/a012 64.2% identity over a 218 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 012 shows 58.7% identity over a 218 aa overlap with a predicted ORF (ORF 012.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 83>:










m012-1.seq




1
ATGCTCGCCC GTTGCCACTT CCTCAATATC CAATTGAGGG CGGTTCTCGC


 


51
TGACAAACTG CTTGAACAAC TGATGCGTTT CCTCCAGTTC CTGTCGGAAT


 


101
TTCTGTTTGC CCTTTTCCGT ATTTTCACCC ATAAAAGTAA CCGTGCGCTT


 


151
AAATTCGCCC GCCGTCATCA CATCCACATC AATATCATGT TTTTTCAACA


 


201
GGCGGTGGAT ATTCGGTACT TCCGCCACCA CACCCACCGA ACCGACAATC


 


251
GCAAACGGAG CGGAAGCAAT TTTATCCGCC ACACACGCCA TCATATAACC


 


301
GCCGCTCGCC GCCACCTTAT CGACGGCGAC GGTCAGCGGA ATATTGCGTT


 


351
CGCGCAAACG CyTAAGCTGC GAAGCCGCCA AACCGTAACC GTGAACCACG


 


401
CCGCCCGGAC TTTCCAATCT GAGCAGAACC TCATCTTCAG GCTTGGCAAT


 


451
CAAAAGCACC GCCGTAATCT CATGACGCAA GGATTCTACG GCGTGTGCAT


 


501
ACAAATCGCC GTCAAAATCC AACACAAAAA GGCGGGATTT TTGCGTTTCG


 


551
GCAGATTTCT CCCCACCCTC CTTCAAACGC TTTTTCTCTG CTTTGGCTTC


 


601
CGCCTTTTCC TTTTTCTTTT CCTCTTTTTC CTGATGTTTT GCCTCTTCCC


 


651
CGCTTAA






This corresponds to the amino acid sequence <SEQ ID 84; ORF 012-1>:










m012-1.pep




1
MLARCHFLNI QLRAVLADKL LEQLMRFLQF LSEFLFALFR IFTHKSNRAL


 


51
KFARRHHIHI NIMFFQQAVD IRYFRHHTHR TDNRKRSGSN FIRHTRHHIT


 


101
AARRHLIDGD GQRNIAFAQT XKLRSRQTVT VNHAARTFQS EQNLIFRLGN


 


151
QKHRRNLMTQ GFYGVCIQIA VKIQHKKAGF LRFGRFLPTL LQTLFLCFGF


 


201
RLFLFLFLFF LMFCLFPA*






m012-1/g012 91.7% identity in 218 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 85>:










a012-1.seq




1
ATGCTCGCCC GTTGCCACTT CCTCAATATC CAATTGAGGG CGGTTCTCGC


 


51
TGACAAACTG CTTGAACAAC TGATGCGTTT CCTCCAGTTC CTGTCGGAAT


 


101
TTCTGTTTGC CCTTTTCCGT ATTTTCACCC ATAAAAGTAA CCGTGCGCTT


 


151
AAATTCGCCC GCCGTCATCA CATCCACATC AATATCATGT TTTTTCAACA


 


201
GGCGGTGGAT ATTCGGTACT TCCGCTACAA CACCCACCGA ACCGACAATC


 


251
GCAAACGGAG CGGAAACAAT TTTATCCGCC ACACACGCCA TCATATAACC


 


301
ACCGCTCGCC GCCACCTTAT CGACGGCGAC GGTCAGCGGA ATATTGCGTT


 


351
CGCGCAAACG CCTAAGCTGC GAAGCCGCCA AACCGTAACC GTGAACCACG


 


401
CCGCCCGGAC TTTCCAATCT AAGCAGAACC TCATCTTCAG GCTTGGCAAT


 


451
CAAAAGCACC GCCGTAATCT CATGACGCAA GGATTCTACG GCGTGTGCAT


 


501
ACAAATCGCC GTCAAAATCC AACACAAAAA GGCGGGATTT TTGCGTTTCG


 


551
GAAGATTTCT CCCCACCCTC CTTCAAACGC TTTTTCTCTG CTTTGGCTTC


 


601
CGCCTTTTCC TTTTTCTTTT CCTCTTTTTC CTGATGTTTT GCCTCTTCCC


 


651
CGCTTAA






This corresponds to the amino acid sequence <SEQ ID 86; ORF 012-1.a>:










a012-1.pep




1
MLARCHFLNI QLRAVLADKL LEQLMRFLQF LSEFLFALFR IFTHKSNRAL


 


51
KFARRHHIHI NIMFFQQAVD IRYFRYNTHR TDNRKRSGNN FIRHTRHHIT


 


101
TARRHLIDGD GQRNIAFAQT PKLRSRQTVT VNHAARTFQS KQNLIFRLGN


 


151
QKHRRNLMTQ GFYGVCIQIA VKIQHKKAGF LRFGRFLPTL LQTLFLCFGF


 


201
RLFLFLFLFF LMFCLFPA*






a012-1/m012-1 97.2% identity in 218 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 87>:










g013.seq




1
aTgcctttga ccatgctgtg cagcaGGAcg tGCGGTTtgt tcataataca


 


51
gtCcgaccGG AAAagcggAG GAAaCGCAGT GCCGCGCCCT TCCCCTTTCT


 


101
TGCCGTGGCA GGCGATGCag tTgGATTCGT ACACTTTTTG CCCTTTtGtc


 


151
atgatGCTgt tgtcggCGGC AGAAGCgGCG GcgCAGAGGC AGCACAAGAT


 


201
GAAGGCGGTC GGCAGTCGGG TTGTGTtcat tGgcgTTTCC cctaatgttt


 


251
tgaaaccttg ttttttgatt Ttgcctttac ggggtgaaaa gtttttTtgg


 


301
cccaaatccg gaatttag






This corresponds to the amino acid sequence <SEQ ID 88; ORF 013.112:










g013.pep




1
MPLTMLCSRT CGLFIIQSDR KSGGNAVPRP SPFLPWQAMQ LDSYTFCPFV


 


51
MMLLSAAEAA AQRQHKMKAV GSRVVFIGVS PNVLKPCFLI LPLRGEKFFW


 


101
PKSGI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 89>:










m013.seq




1
ATGCCTTTGA CCATGCTGTG CAGCAGCACC TGCGGTTTTT TCATGATGAA


 


51
GTCGGAGCGG TAGAGCGGCG GAAACATGGT TCCGCGGCCT TCGCCCTTTT


 


101
TGCCGTGGCA GGCGACGCAG TTGGATTCGT ACACTTTTTG CCCTTTTGTC


 


151
ATGATGCTGT TGTCGGCGGC AGAAGCGGCG GCGCAGAAGC AGCCCAAGAC


 


201
GAGGGCGGTC GGCAGTCGGG TTGTGTTCAT TGGTGTTTCC TTCATGTTTG


 


251
AAACCTTGTT GTTGATTTTG CGTAGCGGGT GAAAGATTTT TTTGCCGAAT


 


301
CAGTAG






This corresponds to the amino acid sequence <SEQ ID 90; ORF 013>.










m013.pep




1
MPLTMLCSST CGFFMMKSER XSGGNMVPRP SPFLPWQATQ LDSYTFCPFV


 


51
MMLLSAAEAA AQKQPKTRAV GSRVVFIGVS FMFETLLLIL RSGXKIFLPN


 


101
Q*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 91>:










a013.seq




1
ATGCCTTTGA CCATGCTGTG CAGCAGCACC TGCGGTTTTT TCATGATGAA


 


51
GTCGGAGCGG TAGAGCGGCG GAAACATGGT TCCGCGGCCT TCGCCCTTTT


 


101
TGCCGTGGCA GGCGACGCAG TTGGATTCGT ACACTTTTTG CCCTTTTGTC


 


151
ATGATGCTGT TGTCGGCGGC AGAAGCGGCG GCGCAGAGGC AGCCCAAGAC


 


201
GAGGGCGGTC GGCAGTCGGG TTGTGTTCAT TGGTGTTTCC TTAATGTTTG


 


251
AAACCTTGTT GTTGATTTTG CGTAGCGGGT GAAAGATTTT CTTGCCGAAT


 


301
CGGTAG






This corresponds to the amino acid sequence <SEQ ID 92; ORF 013.a>:










a013.pep




1
MPLTMLCSST CGFFMMKSER *SGGNMVPRP SPFLPWQATQ LDSYTFCPFV


 


51
MMLLSAAEAA AQRQPKTRAV GSRVVFIGVS LMFETLLLIL RSG*KIFLPN


 


101
R*






m013/a013 97.0% identity over a 101 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 013 shows 73.3% identity over a 101 aa overlap with a predicted ORF (ORF 013.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 93>:










g015.seq




1
ATGCAGTATC TGATTGTCAA ATACAGCCAT CAAATCTTCG TTACCATCAC


 


51
CATTTTGGTA TTCAACATCC GTTTTTTCCT ACTTTGGAAA AATCCAGAAA


 


101
AGCCCTTGGT CGGCTTTTGG AAAGCACTGC CCCACCTCAA CGACACGATG


 


151
CTGCTGTTTA CGGGATTGTG GCTGATGAAG ATTACCCATT TCTCCCCGTT


 


201
CAACGCGCCT TGGCTCGGCA CAAAAATCCT GCTCCTGTTC GCCTACATCG


 


251
CACTGGGCAT GGTAATGATG CGCGCCCGTC CGCGTTCGAC CAAGTTCTAC


 


301
ACCGTTTACC TGCTCGCTAT GTGTTGCATC GCCTGCATCG TTTACCTTGC


 


351
CAAAACCAAA GTCCTGCCAT TCTGA






This corresponds to the amino acid sequence <SEQ ID 94; ORF 015.ng>:










g015.pep




1
MQYLIVKYSH QIFVTITILV FNIRFFLLWK NPEKPLVGFW KALPHLNDTM


 


51
LLFTGLWLMK ITHFSPFNAP WLGTKILLLF AYIALGMVMM RARPRSTKFY


 


101
TVYLLAMCCI ACIVYLAKTK VLPF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 95>:









m015.seq (partial)










1
..AAAATCAGAA AAGCCTTGGC GGGCTTTTGG AAGGCACTGC CCCACCTTAA



 


51
  CGACACCATG CTGCTGTTTA CGGGATTGTG GCTGATGAAA ATTACCCATT


 


101
  TCTCCCCGTT CAACGCGCCT TGGCTCGGTA CAAAAATCCT GCTTCTGCTC


 


151
  GCCTATATCG CATTGGGTAT GATGATGATG CGCGCCCGTC CGCGTTCGAC


 


201
  CAAGTTCTAC ACCGTTTACC TGCTCGCCAT GTGTTGCGTC GCCTGCATCG


 


251
  TTTACCTTGC CAAAACCAAA GTCCTGCCTT TCTGA






This corresponds to the amino acid sequence <SEQ ID 96; ORF 015:









m015.pep (partial)










1
..KIRKALAGFW KALPHLNDTM LLFTGLWLMK ITHFSPFNAP WLGTKILLLL



 


51
  AYIALGMMMM RARPRSTKFY TVYLLAMCCV ACIVYLAKTK VLPF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 97>:










a015.seq




1
ATGCAGTATC TGATTGTCAA ATACAGCCAT CAAATCTTCG TTACCATCAC


 


51
CATTTTGGTA TTCAACATCC GTGTTTTCNT ACTTTGGAAA AATCCAGAAA


 


101
AGCCCTTGGC GGGCTTTTGG AAGGCACTGC CCCACCTTAA CGACACCATG


 


151
CTGCTGTTTA CGGGATTGTG GCTGATGAAA ATTACCCATT TCTCCCCGTT


 


201
CAACGCGCCT TGGCTCGGTA CAAAAATCCT GCTTCTGCTC GCCTATATCG


 


251
CATTGGGTAT GATGATGATG CGCGCCCGTC CGCGTTCGAC CAAGTTCTAC


 


301
ACCGTTTACC TGCTCGCCAT GTGTTGCCTC ACCTGCATCG TTTACCTTGC


 


351
CAAAACCAAA GTCCTGCCTT TCTGA






This corresponds to the amino acid sequence <SEQ ID 98; ORF 015.a>:










a015.pep




1
MQYLIVKYSH QIFVTITILV FNIRVFXLWK NPEKPLAGFW KALPHLNDTM


 


51
LLFTGLWLMK ITHFSPFNAP WLGTKILLLL AYIALGMMMM RARPRSTKFY


 


101
TVYLLAMCCL TCIVYLAKTK VLPF*






m015/a015 96.7% identity over a 91 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 015 shows 94.5% identity over a 91 aa overlap with a predicted ORF (ORF 015.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 99>:










g018.seq




1
atGCAGCAGG GGCagttggt tggacgcgtc gcccgcaata AAGATATGCG


 


51
GAATgctggt CTGCATggtC AGCGGATCGG CAACGGGtac gccgcgcgcg


 


101
tctttgTCGA TATTGATGTT TTCCAAACCG ATATtgTCAA CGTTCGGACG


 


151
GCgACCTACG GCTGCCAACA TATATTCGGC AACAAATACG CCTTTTTCGC


 


201
CATCCTGCTC CCAATGGACT tctACATTGC CGTCTGCGTC GAGTTTGACC


 


251
TCGGTTTTAG CATCCAGATG CAGTTTCAAT tctTCTCCGA ACACGGCTTT


 


301
CGCCTCGTCT GA






This corresponds to the amino acid sequence <SEQ ID 100; ORF 018.ng>:










g018.pep




1
MQQGQLVGRV ARNKDMRNAG LHGQRIGNGY AARVFVDIDV FQTDIVNVRT


 


51
ATYGCQHIFG NKYAFFAILL PMDFYIAVCV EFDLGFSIQM QFQFFSEHGF


 


101
RLV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 101>:










m018.seq




1
ATGCAGCAGA GGCAGTTGGT TGGACGCATC GCCTGCGATG AAGATATGCG


 


51
GAATACTGGT CTGCATGGTC AGCGGGTCGG CAACAGGTAC GCCGCGCGCA


 


101
TCTTTTTCGA TATTGATATT TTCCAAACCG ATATTGTCAA CGTTCGGACG


 


151
GCGGCCCACG GCTGCCAGCA TATATTCGGC AACAAATACG CCTTTTTCGC


 


201
CATCCTGCTC CCAATGGACT TCTACATTGC CGTCTGCATC GAGTTTGACC


 


251
TCGGTTTTAG CATCCAGATG CAGTTTCAAT TCTTCGCCGA ACACGGCGTT


 


301
CGCCTCGTCT GA






This corresponds to the amino acid sequence <SEQ ID 102; ORF 018>:










m018.pep




1
MQQRQLVGRI ACDEDMRNTG LHGQRVGNRY AARIFFDIDI FQTDIVNVRT


 


51
AAHGCQHIFG NKYAFFAILL PMDFYIAVCI EFDLGFSIQM QFQFFAEHGV


 


101
RLV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 103>:










a018.seq




1
ATGCAGCAGG GGCAGTTGGT TGGACGCGTC GCCCGCAATA AAGATATGCG


 


51
GAATACTGGT CTGCATAGTC AGCGGATCGG CAACGGGTAC GCCGCGCGCA


 


101
TCTTTTTCGA TATTGATGTT TTCCAAACCG ATATTGTCAA CGTTCGGACG


 


151
GCGGCCTACG GCTGCCAGCA TATATTCGGC AACAAATACG CCTTTTTCGC


 


201
CATCCTGCTC CCAATGGACT TCTACATTGC CGTCTGCGTC GAGTTTGGCC


 


251
TCGGTTTTAG CATCCAAATG CAGTTTCAAT TCTTCACCGA ACACGGCTTT


 


301
CGCCTCGTCT GA






This corresponds to the amino acid sequence <SEQ ID 104; ORF 018.a>:










a018.pep




1
MQQGQLVGRV ARNKDMRNTG LHSQRIGNGY AARIFFDIDV FQTDIVNVRT


 


51
AAYGCQHIFG NKYAFFAILL PMDFYIAVCV EFGLGFSIQM QFQFFTEHGF


 


101
RLV*






m018/a018 86.4% identity over a 103 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 018 shows 84.5% identity over a 103 aa overlap with a predicted ORF (ORF 018.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 105>:









g019.seq (partial)










1
..ctgctggcgg ccctggtgct tgccgcgtgt tcttcgACAA ACAcacTGCC



 


51
  AGCCGGCAAG ACCCCGGCAG ACAATATAGA AActgcCgAC CTTTCGGCAA


 


101
  GCGTTCCCAC ccgcCCTGCC GAACCGGAAG GAAAAACGCT GGCAGATTAC


 


151
  GGCGGCTACC CGTCCGCACT GGATGCAGTG AAACAGAACA ACGATGCGGC


 


201
  AGCCGCCGCC TATTTGGAAA Acgcaggaga cagCGcgatg gcGGAAAatg


 


251
  tccgcaagga gtgGCTGa






This corresponds to the amino acid sequence <SEQ ID 106; ORF 019.ng>:









g019.pep (partial)









1
..LLAALVLAAC SSTNTLPAGK TPADNIETAD LSASVPTRPA EPEGKTLADY


 


51
  GGYPSALDAV KQNNDAAAAA YLENAGDSAM AENVRKEWL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 107>:









m019.seq (partial)










1
ATGTACCTAC CCTCTATGAA GCATTCCCTG CCGCTGCTGG CGGCCCTGGT



 


51
GCTTGCCGCG TGTTCTTCGA CAAACACACT GCCAGCCGGC AAGACCCCGG


 


101
CAGACAATAT AGAAACTGCC GACCTTTCGG CAAGCGTTCC CACCCGCCCT


 


151
GCCGAACCCG AAAGAAAAAC GCTGGCAGAT TACGGCGGCT ACCCGTCCGC


 


201
ACTGGATGCA GTGAAACAGA AAAACGATGC CGCCGTCGCC GCCTATTTGG


 


251
AAAACGCCGG CGACAGCGCG ATGGCGGAAA ATGTCCGCAA CGAGTGGCTG


 


301
AAGTCTTTGG GCGCACGCAG ACAGTGGACG CTGTTTGCAC AGGAATACGC


 


351
CAAACTCGAA CCGGCAGGGC GCGCCCAAGA AGTCGAATGC TACGCCGATT


 


401
CGAGCCGCAA CGACTATACG CGTGCCGCTG AACTGGTCAA AAATACGGGC


 


451
AAACTGCCTT CGGGCTGCAC CAAACTGTTG GAACAGGCAG CCGCATCCGG


 


501
CTTGTTGGAC GGCAACGACG CCTGGAGGCG CGTGCGCGGA CTGCTGGCCG


 


551
GCCGCCAAAC CACAGACGCA CGCAACCTTG CCGCCGCATT GGGCAGCCCG


 


601
TTTGACGGCG GTACACAAGG TTCGCGCGAA TATGCCCTGT TGAACGTCAT


 


651
CGGCAAAGAA GCACGCAAAT CGCCGAATGC CGCCGCCCTG CTGTCCGAAA


 


701
TGGAAAGCGG TTTAAGCCTC GAACAACGCA GTTTCGCGTG GGGCGTATTG


 


751
GGGCATTATC AGTCGCAAAA CCTCAATGTG CCTGCCGCCT TGGACTATTA


 


801
CGGCAAGGTT GCCGACCGCC GCCAACTGAC CGACGACCAA ATCGAGTGGT


 


851
ACGCCCGCGC CGCCTTGCGC GCCCGACGTT GGGACGAGCT GGCCTCCGTT


 


901
ATCTCGCATA TGCCCGAAAA ACTGCAAAAA AGCCCGACCT GGCTCTACTG


 


951
GCTGGCACGC AGCCGCGCCG CAACGGGCAA CACGCAAGAG GCGGAAAAAC


 


1001
TTTACAAACA GGCGGCAGCG ACGGGCAGGA ATTTTTATGC GGTGCTGGCA


 


1051
GGGGAAGAAT TGGGTCGGAA AATCGATACG CGCAACAATG TGCCCGATGC


 


1101
CGGCAAAAAC AGCGTCCGCC GCATGGCGGA AGACGGTGCA GTCAAACGCG


 


1151
CACTGGTACT GTTCCAAAAC AGCCAATCTG CCGGTGATGC AAAAATGCGC


 


1201
CGTCAGGCTC AGGCGGAATG GCGTTTTGCC ACACGCGGCT TTGACGAAGA


 


1251
CAAGCTGCTG ACCGCCGCGC AAACCGCGTT CGACCACGGT TTTTACGATA


 


1301
TGGCGGTCAA CAGCGCGGAA CGCACCGACC GCAAACTCAA CTACACCTTG


 


1351
CGCTATATTT CGCCGTTTAA AGACACGGTA ATCCGCCACG CGCAAAATGT


 


1401
TAATGTCGAT CCGGCTTGGG TTTATGGGCT GATTCGTCAG GAAAGCCGCT


 


1451
TCGTTATAGG CGCGCAATCC CGCGTAGGCG CGCAGGGGCT GATGCAGGTT


 


1501
ATGCCTGCCA CCGCGCGCGA AATCGCCGGC AAAATCGGTA TGGATGCCGC


 


1551
ACAACTTTAC ACCGCCGACG GG...






This corresponds to the amino acid sequence <SEQ ID 108; ORF 019>:









m019.pep (partial)









1
MYLPSMKHSL PLLAALVLAA CSSTNTLPAG KTPADNIETA DLSASVPTRP


 


51
AEPERKTLAD YGGYPSALDA VKQKNDAAVA AYLENAGDSA MAENVRNEWL


 


101
KSLGARRQWT LFAQEYAKLE PAGRAQEVEC YADSSRNDYT RAAELVKNTG


 


151
KLPSGCTKLL EQAAASGLLD GNDAWRRVRG LLAGRQTTDA RNLAAALGSP


 


201
FDGGTQGSRE YALLNVIGKE ARKSPNAAAL LSEMESGLSL EQRSFAWGVL


 


251
GHYQSQNLNV PAALDYYGKV ADRRQLTDDQ IEWYARAALR ARRWDELASV


 


301
ISHMPEKLQK SPTWLYWLAR SRAATGNTQE AEKLYKQAAA TGRNFYAVLA


 


351
GEELGRKIDT RNNVPDAGKN SVRRMAEDGA VKRALVLFQN SQSAGDAKMR


 


401
RQAQAEWRFA TRGFDEDKLL TAAQTAFDHG FYDMAVNSAE RTDRKLNYTL


 


451
RYISPFKDTV IRHAQNVNVD PAWVYGLIRQ ESRFVIGAQS RVGAQGLMQV


 


501
MPATAREIAG KIGMDAAQLY TADG...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 109>:










a019.seq




1
ATGTACCCAC CCTCTCTGAA GCATTCCCTG CCGCTGCTGG TGGNCCTGGT


 


51
GCTTGCCGCG TGTTCTTNGA CAAACACACT GTCAGCCGAC AAGACCCCGG


 


101
CAGACAATAT AGAAACTGCC GACCTTTCGG CAAGCGTTCC CACCNGCCCT


 


151
GCCGAACCCG AANGAAAAAC GTNGGCAGAT TACGGCGGCT ACCCGTCCGC


 


201
ACTGGATGCA GTGAAACAGA AAAACGATGC CGCCGTCGCC GCCTATTTGG


 


251
AAAACGCCGG CGACAGCGCG ATGGCGGAAA ATGTCCGCAA CGAGTGGCTG


 


301
AAGTCTTTGG GCGCGCGCAG ACAGTGGACG CTGTNTGCAC ANGAATATGC


 


351
NAAACTCGAA CCGGCANGGC GCGCCCAAGA AGTCGAATGC TACGCCGATT


 


401
CGAGCCGCAA CGACTATACG CGTGCCGCCG AACTGGTCAA AAATACGGGC


 


451
AAACTGCCTT CGGGCTGCAC CAAACTGTTG GAACAGGCAG CCGCATCCGG


 


501
CTTGTTGGAC GGCAACGACG CCTGGAGGCG CGTGCGCGGA CTGCTGGCCG


 


551
GCCGCCAAAC CACAGACGCA CGCAACCTTG CCGCCGCATT GGGCAGCCCG


 


601
TTTGACGGCG GTACACAAGG TTCGCGCGAA TATGCCCTGT TGAACGTCAT


 


651
CGGCAAAGAA GCACGCAAAT CGCCGAATGC CGCCGCCCTG CTGTCCGAAA


 


701
TGGAAAGCGG TTTAAGCCTC GAACAACGCA GTTTCGCGTG GGGCGTATTG


 


751
GGGCATTATC AGTCGCAAAA CCTCAATGTG CCTGCCGCCT TGGACTATTA


 


801
NGGCAAGGTT GCCGACCGCC GCCAACTGAC CGACGACCAA ATCGAGTGGT


 


851
ACGCCCGCGC CGCNNTNNGC NNNCGNNGTT NGNANGANNT GGCNNCCGNN


 


901
ANCNCGNNNN TGCNNGANAA ACNNNNNNAN AGNCNNANNT NGNTNNANTG


 


951
NNTGGCACGC AGCCGCGCCG CNACGGGCAA CACGCAANAN GCGGANAAAC


 


1001
TNTACAAACA GGCGGCAGCA NCGGGCANGA ATTTTTATGC NGTGCTGNCN


 


1051
GGGGAAGAGT TGGGGCGCAN AATCGATACG CGCAACAATG TGCCCGATGC


 


1101
CGGCAAAANC AGCGTCCTCC GTATGGCGGA AGACGGCGCG ATTAAGCGCG


 


1151
CGCTGGTGCT GTTCCGAAAC AGCCGAACCG CCGGCGATGC GAAAATGCGC


 


1201
CGTCNGGCTC AGGCGGAATG GCGTTTCGCC ACACGCGGCT TCGATGAAGA


 


1251
CAAGCTGCTG ACCGCCGCGC AAACCGCGTT CGACCACGGT TTTTACGATA


 


1301
TGGCGGTCAA CAGCGCGGAA CGCACCGACC GCAAACTCAA CTACACCTTG


 


1351
CGCTACATTT CGNNNNNTNA NGACACGGTA ATCCGCCACG CGCAAAATGT


 


1401
TAATGTCGAT CCGGCGTGGG TTTACGGGCT GATTCGTCAG GAAAGCCGCT


 


1451
TCGTTATGGG CGCGCAATCC CGCGTAGGCG CGCAGGGGCT GATGCAGGTT


 


1501
ATGCCTGCCA CCGCGCGCGA AATCGCCGGC AAAATCGGTA TGGATGCCGC


 


1551
ACAACTTTAC ACCGCCGACG GCAATATCCG TATGGGGACG TGGTATATGG


 


1601
CGGACACCAA ACGCCGCCTG CAAAACAACG AAGTCCTCGC CACCGCAGGC


 


1651
TATAACGCCG GTCCCGGCAG GGCGCGCCGA TGGCAGGCGG ACACGCCCCT


 


1701
CGAAGGCGCG GTATATGCCG AAACCATCCC GTTTTCCGAA ACGCGCGACT


 


1751
ATGTCAAAAA AGTGATGGCC AATGCCGCCT ACTACGCCTC CCTCTTCGGC


 


1801
GCGCCGCACA TCCCGCTCAA ACAGCGTATG GGCATTGTCC CCGCCCGCTG


 


1851
A






This corresponds to the amino acid sequence <SEQ ID 110; ORF 019.a>:










a019.pep




1
MYPPSLKHSL PLLVXLVLAA CSXTNTLSAD KTPADNIETA DLSASVPTXP


 


51
AEPEXKTXAD YGGYPSALDA VKQKNDAAVA AYLENAGDSA MAENVRNEWL


 


101
KSLGARRQWT LXAXEYAKLE PAXRAQEVEC YADSSRNDYT RAAELVKNTG


 


151
KLPSGCTKLL EQAAASGLLD GNDAWRRVRG LLAGRQTTDA RNLAAALGSP


 


201
FDGGTQGSRE YALLNVIGKE ARKSPNAAAL LSEMESGLSL EQRSFAWGVL


 


251
GHYQSQNLNV PAALDYXGKV ADRRQLTDDQ IEWYARAAXX XRXXXXXAXX


 


301
XXXXXXKXXX XXXXXXXXAR SRAATGNTQX AXKLYKQAAA XGXNFYAVLX


 


351
GEELGRXIDT RNNVPDAGKX SVLRMAEDGA IKRALVLFRN SRTAGDAKMR


 


401
RXAQAEWRFA TRGFDEDKLL TAAQTAFDHG FYDMAVNSAE RTDRKLNYTL


 


451
RYISXXXDTV IRHAQNVNVD PAWVYGLIRQ ESRFVMGAQS RVGAQGLMQV


 


501
MPATAREIAG KIGMDAAQLY TADGNIRMGT WYMADTKRRL QNNEVLATAG


 


551
YNAGPGRARR WQADTPLEGA VYAETIPFSE TRDYVKKVMA NAAYYASLFG


 


601
APHIPLKQRM GIVPAR*






m019/a019 88.9% identity over a 524 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 019 shows 95.5% identity over a 89 aa overlap with a predicted ORF (ORF 019.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 111>:










g023.seq




1
ATGGTAGAAC GTAAATTGAC CGGTGCCCAT TACGGTTTGC GCGATTGGGT


 


51
AATGCAGCGT GCGACTGCGG TTATTATGTT GATTTATACC GTTGCACTTT


 


101
TAGTGGTTCT ATTTGCCCTG CCTAAAGAAT ATCCGGCATG GCAGGCATTT


 


151
TTTAGTCAAG CTTGGGTAAA AGTATTTACC CAAGTGAGCT TTATCGCCGT


 


201
ATTCTTGCAC GCTTGGGTGG GTATCCGCGA TTTGTGGATG GACTATATCA


 


251
AACCCTTCGG CGTGCGTTTG TTTTTGCAGG TTGCCACCAT TGtctGGCTG


 


301
GTCGGCTGCC TCGTGTATTC AGTTAAAGTG ATTTGGGGGT AA






This corresponds to the amino acid sequence <SEQ ID 112; ORF 023.ng>:










g023.pep




1
MVERKLTGAH YGLRDWVMQR ATAVIMLIYT VALLVVLFAL PKEYPAWQAF


 


51
FSQAWVKVFT QVSFIAVFLH AWVGIRDLWM DYIKPFGVRL FLQVATIVWL


 


101
VGCLVYSVKV IWG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 113>:










m023.seq




1
ATGGTAGAAC GTAAATTGAC CGGTGCCCAT TACGGTTTGC GCGATTGGGT


 


51
GATGCAACGT GCGACTGCGG TTATTATGTT GATTTATACC GTTGCACTTT


 


101
TAGTGGTTCT ATTTTCCCTG CCTAAAGAAT ATTCGGCATG GCAGGCATTT


 


151
TTTAGTCAAA CTTGGGTAAA AGTATTTACC CAAGTGAGCT TCATCGCCGT


 


201
ATTCTTGCAC GCTTGGGTGG GTATCCGCGA TTTGTGGATG GACTATATCA


 


251
AACCCTTCGG CGTGCGTTTG TTTTTGCAGG TTGCCACCAT CGTTTGGCTG


 


301
GTCGGCTGTC TCGTGTATTC AGTTAAAGTG ATTTGGGGGT AA






This corresponds to the amino acid sequence <SEQ ID 114; ORF 023>:










m023.pep




1
MVERKLTGAH YGLRDWVMQR ATAVIMLIYT VALLVVLFSL PKEYSAWQAF


 


51
FSQTWVKVFT QVSFIAVFLH AWVGIRDLWM DYIKPFGVRL FLQVATIVWL


 


101
VGCLVYSVKV IWG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 115>:










a023.seq




1
ATGGTAGAAC GTAAATTGAC CGGTGCCCAT TACGGTTTGC GGGATTGGGC


 


51
GATGCAACGT GCGACCGCGG TTATTATGTT GATTTATACC GTTGCACTTT


 


101
TAGTGGTTCT ATTTGCTCTG CCTAAAGAAT ATTCGGCATG GCAGGCATTT


 


151
TTTAGTCAAA CTTGGGTAAA AGTATTTACC CAAGTGAGCT TCATCGCCGT


 


201
ATTCTTGCAC GCTTGGGTGG GTATCCGCGA TTTGTGGATG GACTATATNA


 


251
AACCCTTCGG CGTGCGTTTG TTTTTGCAGG TTGCCACCAT CGTCTGGCTG


 


301
GTCGGCTGCT TGGTGTATTC AATTAAAGTA ATTTGGGGGT AA






This corresponds to the amino acid sequence <SEQ ID 116; ORF 023.a>:










a023.pep




1
MVERKLTGAH YGLRDWAMQR ATAVIMLIYT VALLVVLFAL PKEYSAWQAF


 


51
FSQTWVKVFT QVSFIAVFLH AWVGIRDLWM DYXKPFGVRL FLQVATIVWL


 


101
VGCLVYSIKV IWG*






m023/a023 96.5% identity over a 113 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 023 shows 97.3% identity over a 113 aa overlap with a predicted ORF (ORF 023.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 117>:










g025.seq




1
ATGTTGAAAC AAAcgACACT TTTGGCAGCT TGTACCGCCG TTGCCGCTCT


 


51
GTTGGGCGGT TGcgCCACCC AACAGCCTGC TccTGTCATT GCAGGCAATT


 


101
CAGGTATGCA GACCGTATCG TCTGCGCCGG TTTACAATCC TTATGGCGCA


 


151
ACGCCGTACA ATGCCGCTCC TGCCGCCAac gatgcGCCgT ATGTGCCGCC


 


201
CGTGCAAact gcgccggttT ATTCGCCTCC TGCTTATGTT CCGCcgtCTG


 


251
CACCTGCCGT TTCGGgtaca tatgtTCCTT CTTACGCACC CgtcgACATC


 


301
aacgCGGCGa cgCataCTAT TGTGCGTGGC GACACgGtgt acaACATTTc


 


351
caaAcgCtac CATATCTCTC AAGACGATTT CCGTGCGTGG AACGGCATGA


 


401
CCGACAATAC GTTGAGCATC GGTCAGATTG TTAAAGTCAA ACCGGCaggA


 


451
TATGCCGCAC CGAAAACCGC AGCCGTAGAA AGCAGGCCCG CCGTACCGGC


 


501
TGCCGCGCAA ACCCCTGTGA AACCCGCCGC gcaACCGCCC GTTCAGTCCG


 


551
CGCCGCAACC TGCCGCGCCC GCTGCGGAAA ATAAAGCGGT TCCCGCCCCC


 


601
GCGCCCGCCC CGCAATCTCC TGCCGCTTCG CCTTCCGGCA CGCGTTCGGT


 


651
CGGCGGCATT GTTTGGCAGC GTCCGACCCA AGGTAAAGTG GTTGCCGATT


 


701
TCGGCGGCGG CAACAAGGGT GTCGATATTG CCGGCAATGC CGGACAACCC


 


751
GTTTTGGCGG CGGCTGACGG CAAAGTGGTT TATGCCGGTT CAGGTTTGAG


 


801
GGGATACGGA AACTTGGTCA TCATCCAGCA CAATTCCTCT TTCCTGACCG


 


851
CGTACGGGCA CAACCAAAAA TTGCTGGTCG GCGAAGGTCA GCAGGTCAAA


 


901
CGCGGTCAGC AGGTTGCTTT GATGGGTAAT ACCGATGCTT CCAGAACGCA


 


951
GCTTCATTTC GAGGTGCGTC AAAACGGCAA ACCGGTTAAC CCGAACAGCT


 


1001
ATATCGCGTT CTGA






This corresponds to the amino acid sequence <SEQ ID 118; ORF 025.ng>:










g025.pep




1
MLKQTTLLAA CTAVAALLGG CATQQPAPVI AGNSGMQTVS SAPVYNPYGA


 


51
TPYNAAPAAN DAPYVPPVQT APVYSPPAYV PPSAPAVSGT YVPSYAPVDI


 


101
NAATHTIVRG DTVYNISKRY HISQDDFRAW NGMTDNTLSI GQIVKVKPAG


 


151
YAAPKTAAVE SRPAVPAAAQ TPVKPAAQPP VQSAPQPAAP AAENKAVPAP


 


201
APAPQSPAAS PSGTRSVGGI VWQRPTQGKV VADFGGGNKG VDIAGNAGQP


 


251
VLAAADGKVV YAGSGLRGYG NLVIIQHNSS FLTAYGHNQK LLVGEGQQVK


 


301
RGQQVALMGN TDASRTQLHF EVRQNGKPVN PNSYIAF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 119>:










m025.seq (partial)











1
..GTGCCGCCGG TGCAAAGCGC GCCGGTTTAT ACGCCTCCTG CTTATGTTCC



 


51
  GCCGTCTGCA CCTGCCGTTT CGGGTACATA CGTTCCTTCT TACGCACCCG


 


101
  TCGACATCAA CGCGGCGACG CATACTATTG TGCGCGGCGA CACGGTGTAC


 


151
  AACATTTCCA AACGCTACCA TATCTCTCAA GACGATTTCC GTGCGTGGAA


 


201
  CGGCATGACC GACAATACGT TGAGCATCGG TCAGATTGTT AAAGTCAAAC


 


251
  CGGCAGGATA TGCCGCACCG AAAGCCGCAG CCGTAAAAAG CAGGCCCGCC


 


301
  GTACCGGCTG CCGCGCAACC GCCCGTACAG TCCGCACCCG TCGACATTAA


 


351
  CGCGGCGACG CATACTATTG TGCGCGGCGA CACGGTGTAC AACATTTCCA


 


401
  AACGCTACCA TATCTCTCAA GACGATTTCC GTGCGTGGAA CGGCATGACC


 


451
  GACAATATGT TGAGCATCGG TCAGATTGTT AAAGTCAAAC CGGCAGGATA


 


501
  TGCCGCACCG AAAACCGCAG CCGTAGAAAG CAGGCCCGCC GTACCGGCTG


 


551
  CCGTGCAAAC CCCTGTGAAA CCCGCCGCGC AACCGCCTGT GCAGTCCGCG


 


601
  CCGCAACCTG CCGCGCCCGC TGCGGAAAAT AAAGCGGTTC CCGCGCCCGC


 


651
  CCCGCAATCT CCTGCCGCTT CGCCTTCCGG CACGCGTTCG GTCGGCGGCA


 


701
  TTGTTTGGCA GCGTCCGACG CAAGGTAAAG TGGTTGCCGA TTTCGGCGGC


 


751
  AACAACAAGG GTGTCGATAT TGCCGGTAAT GCGGGACAGC CCGTTTTGGC


 


801
  GGCGGCTGAC GGCAAAGTGG TTTATGCCGG TTCAGGTTTG AGGGGATACG


 


851
  GAAACTTGGT CATCATCCAG CATAATTCTT CTTTCCTGAC CGCATACGGG


 


901
  CACAACCAAA AATTGCTGGT CGGCGAGGGG CAGCAGGTCA AACGCGGTCA


 


951
  GCAGGTTGCT TTGATGGGCA ATACCGATGC TTCCAGAACG CAGCTTCATT


 


1001
  TCGAGGTGCG TCAAAACGGC AAACCGGTTA ACCCGAACAG CTATATCGCG


 


1051
  TTCTGA






This corresponds to the amino acid sequence <SEQ ID 110; ORF 025>:










m025.pep (partial)











1
..VPPVQSAPVY TPPAYVPPSA PAVSGTYVPS YAPVDINAAT HTIVRGDTVY



 


51
  NISKRYHISQ DDFRAWNGMT DNTLSIGQIV KVKPAGYAAP KAAAVKSRPA


 


101
  VPAAAQPPVQ SAPVDINAAT HTIVRGDTVY NISKRYHISQ DDFRAWNGMT


 


151
  DNMLSIGQIV KVKPAGYAAP KTAAVESRPA VPAAVQTPVK PAAQPPVQSA


 


201
  PQPAAPAAEN KAVPAPAPQS PAASPSGTRS VGGIVWQRPT QGKVVADFGG


 


251
  NNKGVDIAGN AGQPVLAAAD GKVVYAGSGL RGYGNLVIIQ HNSSFLTAYG


 


301
  HNQKLLVGEG QQVKRGQQVA LMGNTDASRT QLHFEVRQNG KPVNPNSYIA


 


351
  F*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 111>:










a025.seq




1
ATGTTGACAC CAACAACACT TTAGGTAGCT TGTACCGCCC TTGCCGCTCA


 


51
GTTGGGCGGA TGCCCCACCC AACACCCTTC TCCTGTCATT GCAGGCAATT


 


101
CAGGTATGCA GACCGTACCG TCTGCGCCGG TTTACAATCC TTATGGCGCA


 


151
ACGCCGTACA ATGCCGCTCC TGCCGCCAAC GATGCGCCGT ATGTGCCGCC


 


201
GGTGCAAAGC GCGCCGGTTT ATANGCCTCC TGCTTATGTT CCGCCGTCTG


 


251
CACCTGCCGT TTCGGGTACA TACGTTCCTT CTTACGCANC CGTCGACATC


 


301
AACGCGGCGA CCCATACTAT TGTGCGCGGC GACACCGTGT ACAAGATTTC


 


351
CAAATGCTAC CATATCTCTC AAGACGATTT CCGTGCGTGG AACGGCATGA


 


401
CCGACAATAC GTTGAGCATC GGTCAGATTG TTAAAGTCAA ACCGGCAGGA


 


451
TATGCCGCAC CGAAAGCCGC AGCCGTAAAA AGCAGGCCCG CCGTACCGGC


 


501
TGCCGCGCAA CCGCTCGTAC AGTCCGCACC CGTCGACATC AACGCGGCGA


 


551
CGCATACTAT TGTGCGCGGC GACACGGTGT ACAACATTTC CAAACGCTAC


 


601
CATATCTCTC AAGACGATTT CCGTGCGTGG AACGGCATGA CCGACAATAC


 


651
GTTGAGCATC GGTCAGATTG TTAAAGTCAA ACCGGCAGGA TATGCCGCAC


 


701
CGAAAGCCGC AGCCGTAAAA AGCAGGCCCG CCGTACCGGC TGCCGTGCAA


 


751
ACCCCTGTGA AACCCGCCGC GCAACCGCCT GTGCAGTCCG CGCCGCAACC


 


801
TGCCGCGCCC GCTGCGGAAA ATAAAGCGGT TCCCGCGCCC GCCCCGCAAT


 


851
CTCCTGCCGC TTCGCCTTCC GGCACGCGTT CGGTCGGCGG CATTGTTTGG


 


901
CAGCGTCCGA CGCAAGGTAA AGTGGTTGCC GATTTCGGCG GCAACAACAA


 


951
GGGTGTCGAT ATTGCAGGAA ATGCGGGACA GCCCGTTTTG GCGGCGGCTG


 


1001
ACGGCAAAGT GGTTTATGCA GGTTCCGGTT TGAGGGGATA CGGCAATTTG


 


1051
GTCATCATCC AGCATAATTC TTCCTTCCTG ACCGCATACG GGCACAACCA


 


1101
AAAATTGCTG GTCGGCGAAG GCCAGCAGGT CAAACGCGGG CAGCAGGTCG


 


1151
CTTTGATGGG CAATACCGAG GCTTCTAGAA CGCAGCTTCA TTTCGAGGTG


 


1201
CGGCAAAACG GCAAACCGGT TAATCCGAAC AGCTATATCG CGTTCTGA






This corresponds to the amino acid sequence <SEQ ID 112; ORF 025.a>:










a025.pep




1
MLTPTTL*VA CTALAAQLGG CPTQHPSPVI AGNSGMQTVP SAPVYNPYGA


 


51
TPYNAAPAAN DAPYVPPVQS APVYXPPAYV PPSAPAVSGT YVPSYAXVDI


 


101
NAATHTIVRG DTVYKISKCY HISQDDFRAW NGMTDNTLSI GQIVKVKPAG


 


151
YAAPKAAAVK SRPAVPAAAQ PLVQSAPVDI NAATHTIVRG DTVYNISKRY


 


201
HISQDDFRAW NGMTDNTLSI GQIVKVKPAG YAAPKAAAVK SRPAVPAAVQ


 


251
TPVKPAAQPP VQSAPQPAAP AAENKAVPAP APQSPAASPS GTRSVGGIVW


 


301
QRPTQGKVVA DFGGNNKGVD IAGNAGQPVL AAADGKVVYA GSGLRGYGNL


 


351
VIIQHNSSFL TAYGHNQKLL VGEGQQVKRG QQVALMGNTE ASRTQLHFEV


 


401
RQNGKPVNPN SYIAF*






m025/a025 97.4% identity over a 351 aa overlap




Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 025 shows 75.6% identity over a 353 aa overlap with a predicted ORF (ORF 025.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 113>:










g031.seq




1
ATGGTGTCCC TCCGCTTCAG ATTCGGCAAC CACTTTAAAC GCCGACATTC


 


51
TGACAATTTC CTTTTCCGCC AGCCAAATAT CATGCGTATC TTTCGGTTCG


 


101
GGCTTGTTGG GCATGGCAAC CTTCAACAGC CGCGCCATCA CAGGAATCGT


 


151
CGTTCCCTGA ATCAGCAGCG ACAGCACCAC CACGGCAAAC GCCACATCAA


 


201
ACAGCAGGTG CGAATTGGGA ACGCCCATCA CCAGCGGCAT CATCGCCAGC


 


251
GAAATCGGTA CGGCTCCTCG CAAGCCCAAC CAACTGATAT ACGCCTTTTC


 


301
ACGCAGGCTG TAATTGAATT TCCACAAACC GCCGAACACT GCCAGCGGAC


 


351
GCGCGACCAG CATCAGGAAC GCCGCAATCG CCAAGGCTTC CGCCGCCCTG


 


401
TCCAACACGC CGGCGGGAGA AACCAGCAGA CCGAGCATGA CGAACAAAGT


 


451
TGCCTGCGCC AGCCAAGCCA AACCGTCCAT CACACGCAAA ACGTGTTCCG


 


501
TcgcACGGTT GCGCTGGTTA CCGACAATGA TGCCGGCAAG GTAAACCGCC


 


551
AAAAAGCCGC TGCCGCCTAT GGTATTGGTA AACGCAAACA CAAGCAGCCC


 


601
GCCCGACACA ATCATCAGCG CGTACAGACC TTCCGtacac acctccaatt


 


651
cccaatcaac gtcatagctg tctcccgtgt taaaatgttc ttcacttcag


 


701
aatccccccc ttcttcccag cccgaaacct tcatgtgtta naccctgggg


 


751
tgccccaacg gatttagtaa cctcccaatg actctgcttg tcgccccctt


 


801
cgcccgcttt ctccttccgg gaaaacttgt tgtccccgtc ttacattaa






This corresponds to the amino acid sequence <SEQ ID 114; ORF 031.ng>:










g031.pep




1
MVSLRFRFGN HFKRRHSDNF LFRQPNIMRI FRFGLVGHGN LQQPRHHRNR


 


51
RSLNQQRQHH HGKRHIKQQV RIGNAHHQRH HRQRNRYGSS QAQPTDIRLF


 


101
TQAVIEFPQT AEHCQRTRDQ HQERRNRQGF RRPVQHAGGR NQQTEHDEQS


 


151
CLRQPSQTVH HTQNVFRRTV ALVTDNDAGK VNRQKAAAAY GIGKRKHKQP


 


201
ARHNHQRVQT FRTHLQFPIN VIAVSRVKMF FTSESPPSSQ PETFMCXTLG


 


251
CPNGFSNLPM TLLVAPFARF LLPGKLVVPV LH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 115>:










m031.seq (partial)










1
...CGCCTGAAGC ACGGTGTCGG ACTGCATTTC TATTCGGCTA TACGCCTTTT


 


51
   CACGCAGGCT GTAATTGAAT TTCCACAAAC CGCCGAACAC TGCCGACGGA


 


101
   CGCGCGACCA GCATCAGGAA CGCCGCAATC GCCAAgGCTT CCGCCGCCCT


 


151
   GTCCAACACG TTGGCAGGAG AAACCAGCAG CAAAGGCATT CCCAAACGTG


 


201
   CGGACAAAGT GGTCGAAACC ACGCTCAGAA ACAACAGTGC GCCACCCGGC


 


251
   AG....






This corresponds to the amino acid sequence <SEQ ID 116; ORF 031>:










m031.pep (partial)










1
...RLKHGVGLHF YSAIRLFTQA VIEFPQTAEH CRRTRDQHQE RRNRQGFRRP


 


51
   VQHVGRRNQQ QRHSQTCGQS GRNHAQKQQC ATRQ....






The following partial DNA sequence was identified in N. meningitidis SEQ ID 117>:










a031.seq




1
ATACGCCTTT TCACGCAGGC TGTAATTGAA TTTCCACAAA CCGCCGAACA


 


51
CTGCCGGCGG ACGCGCGACC AGCATCAGGA ACGCCGCAAT CGCCAAGGCT


 


101
TCCGCCGCCC CGTCCAACAC GTTGGCAGGA GAAACCAGCA GCAAAGGCAT


 


151
TCCCAAACGT GCGGACAAAG TGGTCGAAAC CACGCTCAGA AACAACAGTG


 


201
CGCCACCCGG CAG






This corresponds to the amino acid sequence <SEQ ID 118; ORF 031.a>:










a031.pep (partial)










1
IRLFTQAVIE FPQTAEHCRR TRDQHQERRN RQGFRRPVQH VGRRNQQQRH


 


51
SQTCGQSGRN HAQKQQCATR Q






m031/a031 100.0% identity over a 71 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 031 shows 60.0% identity over a 85 aa overlap with a predicted ORF (ORF 031.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 119>:










g032.seq




1
ATGCGGCGAA ACGTGCCTGC CGTCGCCGTA TTGCGCCGCC CACGATTCGA


 


51
GGCGTTTTTG GATTTGGCGT TGGCTCAGGC GCGTGCCGTT CCTGCCGGTA


 


101
AACAGGGCTT TGCCGTCCGA TGCCGTCTGA CGCAGCGGCA GATAGTTTTT


 


151
CAAGGCTTCC ACGCTTTTGC CGGTCAGCGG AACCTGACGC TGCTTGCGCC


 


201
CTTTGCCGGT AACGTGTACC CACGCTTCGT CCAAATATAC ATCATCTGCA


 


251
TTCAAGCCGT GTATCTCGCT CACGCGCAAA CCGCTGCCGT ACATCAGCTC


 


301
GAACAGCGCG TGGTCGCGCA CCGCCAGCGG GTCGCCGCCG TCCACGGGCA


 


351
AATCCAACAT CCGGTTCAGC CATTCCTGCG GCAGGGCTTT GGGTACGCGC


 


401
TCGGGCTGCT TCGGCGGTTT GATGTCGGCG GTCGGGTCGG CGCGCATCAG


 


451
CCCGCGTTTG ACCAGCCAGG CGCAATACTG CCGCCACGCC GACAGCTTGC


 


501
GCGCCAGCGT CCGACCGTCC AAACCGCGCT GCGACAGCCG CCGCAACGCC


 


551
GccgTAAAAT CGCGCCGCGA CAAGTCCTGC GGCACGCcgc ctgcaTCTTC


 


601
AGACGGCATT TGTGCCAACA GTGCAAACAG TTCTTCCAAA TCGCGCCGGT


 


651
ATGCCGCAAC CGTGTGCTCC GACTTGCCCT CGCGCACGAT GTTTTCCAAA


 


701
TAAGCGTCAA AATacgccgC AAACccgTCC AAAACCATAA CCGTCCCACA


 


751
CAAATATCAA AAAACCAGTG A






This corresponds to the amino acid sequence <SEQ ID 110; ORF 032.ng>:










g032.pep




1
MRRNVPAVAV LRRPRFEAFL DLALAQARAV PAGKQGFAVR CRLTQRQIVF


 


51
QGFHAFAGQR NLTLLAPFAG NVYPRFVQIY IICIQAVYLA HAQTAAVHQL


 


101
EQRVVAHRQR VAAVHGQIQH PVQPFLRQGF GYALGLLRRF DVGGRVGAHQ


 


151
PAFDQPGAIL PPRRQLARQR PTVQTALRQP PQRRRKIAPR QVLRHAACIF


 


201
RRHLCQQCKQ FFQIAPVCRN RVLRLALAHD VFQISVKIRR KPVQNHNRPT


 


251
QISKNQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 111>:









m032.seq (partial)










1
ATGCGGCGAA ACGTGCmTGC mGTCGCCGTT kTGCGCCGCC CATTGCGCCA



 


51
AACGTTTTTG GATTTGGCGT TGGCTCAGGC GCGTGCCGTT CCTGCCGGTA


 


101
AACAGGGCTT TGCCGTCCGA TGCCGTCTGA CGCAGCGGCA GATAGTTTTT


 


151
CAGGGCTTCC ACGCTTTTGC CGACCAGCGG CACCTGCCGC TgTT.GCGCC


 


201
CTTTGCCGAT AAcGTGTACC CACGCyTCGT CCAAATAGAC ATCATCTGCA


 


251
TTCAAGCCGT GTATCTCGCT CACGCGCAAA CCGCTGCCGT ACATCAGTTC


 


301
GAACAGGGCG TGGTCGCGCA CCGCCAGCGG GTCGCCGCCG TCCACGGGCA


 


351
AATCCAGCAT CCGGTTCAGC CATTCCTGCG GCAGGGCTTT GGGTACGCGC


 


401
TCGGGCTGCT TCGGCGGTTT GATGTCGGCG GTCGGGTCGG CGTGCATCAG


 


451
GCCGCGCTTT ACCAGCCAAA CGCAATACTG CCGCCAAGAC GAAAGCTTGC


 


501
GAGCCAGCGT CCGTTCCCCC AAACCGCG...






This corresponds to the amino acid sequence <SEQ ID 112; ORF 032>:









m032.pep (partial)










1
MRRNVXAVAV XRRPLRQTFL DLALAQARAV PAGKQGFAVR CRLTQRQIVF



 


51
QGFHAFADQR HLPLXAPFAD NVYPRXVQID IICIQAVYLA HAQTAAVHQF


 


101
EQGVVAHRQR VAAVHGQIQH PVQPFLRQGF GYALGLLRRF DVGGRVGVHQ


 


151
AALYQPNAIL PPRRKLASQR PFPQTA...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 113>:










a032.seq




1
ATGCGGCGAA ACGTGCCTGC CGTCGCCGTT TTGCGCCGCC CATTGCGCCA


 


51
AACGTTTTTG GATTTGGCGT TGGCTCAGGC GCGTGCCGTT CCTGCCGGTA


 


101
AACAGGGCTT TGCCGTCCGA TGCCGTCTGA CGCAGCGGCA GATAGTTTTT


 


151
CAGGGCTTCC ACGCTTTTGC CGGTCAGCGG AACCTGCCGC TGCTTGCGTC


 


201
CTTTGCCGGT AACGTGTACC CACGCCTCGT CCAAATATAC ATCATCTGCA


 


251
TTCAAGCCGT GTATCTCGCT CACGCGCAAA CCGCTGCCGT ACATCAGTTC


 


301
GAACAGCGCG TGATCGCGCA CCGCCAGCGG GTCGCCGCCG TCCACGGGCA


 


351
AATCCAGCAT CCGGTTCAGC CATTCCTGCG GCAGGGCTTT GGGTACGCGC


 


401
TCGGGCTGCT TCGGCGGTTT GATGTCGGCG GTCGGGTCGG TATGCAGCAG


 


451
ACCGCGTTTG ACCAGCCAGG CGCAATACTG CCGCCAAGAC GACAGCTTGC


 


501
GCGCCAGCGT CCGCGCATTC AAACCGCGCT GCGACAGCCG CCGCAACGCC


 


551
GCCGTAAAAT CGCGCTGCGA CAAGCCCTGC GGCACGCCGC CTGCATCTTC


 


601
AGACGGCATT TGTGCCAACA GCGCAAACAG TTCTTCCAAA TCGCGCCGGT


 


651
ATGCCGCCAC CGTGTGCTCC GACTTGCCCT CGCGCACGAT GTTTTCCAAA


 


701
TAAGCGTCAA AATGCGCCGC AAACCCGTCC AAAACCATAA CCGCCCCACA


 


751
CAAATATCAA AAAAACAGTG A






This corresponds to the amino acid sequence <SEQ ID 114; ORF 032.a>:










a032.pep




1
MRRNVPAVAV LRRPLRQTFL DLALAQARAV PAGKQGFAVR CRLTQRQIVF


 


51
QGFHAFAGQR NLPLLASFAG NVYPRLVQIY IICIQAVYLA HAQTAAVHQF


 


101
EQRVIAHRQR VAAVHGQIQH PVQPFLRQGF GYALGLLRRF DVGGRVGMQQ


 


151
TAFDQPGAIL PPRRQLARQR PRIQTALRQP PQRRRKIALR QALRHAACIF


 


201
RRHLCQQRKQ FFQIAPVCRH RVLRLALAHD VFQISVKMRR KPVQNHNRPT


 


251
QISKKQ*






m032/a032 88.1% identity over a 176 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 032 shows 86.4% identity over a 176 aa overlap with a predicted ORF (ORF 032.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 115>:










g033.seq




1
ATGGCGGCGG CGGACAAACT CTTGGGCGGC GACCGCCGCA GCGTCGCCAT


 


51
CATCGGAGAC GGCGCGATGA CGGCGGGGCA GGCGTTTGAA GCCTTGAATT


 


101
GCGCGGGCGA TATGGATGTG GATTTGCTGG TCGTCCTCAA CGACAACGAA


 


151
ATGTCGATTT CCCCCAACGT CGGCGCGTTG CCCAAATATC TTGCCAGCAA


 


201
CGTCGTGCGC GATATGCACG GACTGTTGAG TACCGTCAAA GCGCAAAcgg


 


251
GCAAGGTATT AGACAAAATA CCCGGCGCGA TGGagtTTGC CCAAAAAGTC


 


301
GAACAcaaaA TCAAAACCCT TGCCGAAGAA GCCGAACACG CCAAACAGTC


 


351
GCTGTCGCTG TTTGAAAATT TCGGCTTCCG CTACACCGGC CCCGTGGACG


 


401
GACACAACGT CGAGAATCTG GTGGACGTAT TGAAAGACTT GCGCAGCCGC


 


451
AAAGGCCCTC AGTTGCTGCA CGTCATCACC AAAAAGGGCA ACGGCTACAA


 


501
ACTCGCCGAA AACGACCCcg tcaAATACCA CGCCGTCGCc aACCTGCcta


 


551
AAGAAGGCGG GGCGCAAATg ccGTCTGAAA AAGAACCCAA GCCCGCCgCc


 


601
aaaccgACCT ATACCCAAGT ATTCGGCAAA TGGCTGTGCG ACCGGGCGGC


 


651
GGCAGATTCC CGACTGGTTG CGATTACCCC CGCCATGCGC GAGGGCAGCG


 


701
GACTGGTGGA GTTTGAACAA CGATTCCCCG ACCGCTATTT CGATGTCGGC


 


751
ATCGCCGAGC AGCACGCCGT tacCTTTGCC GGCGGTTTGG CGTGCGAAGG


 


801
CATGAAGCCC GTCGTGGCGA TTTATTCCAC CTTTTTACAA CGCGCCTACG


 


851
ACCAACTGGT GCACGACATC GCCCTGCAAA ACCTGCCCGT TTTGTTTGCC


 


901
GTCGACCGTG CGGGCATCGT CGGCGCGGAC GGTCCGACCC ATGCCGGCTT


 


951
GTACGATTTG AGCTTCTTGC GCTGTGTGCC GAACATGATT GTTGCCGCGC


 


1001
CGAGCGATGA AAACGAATGC CGCCTGCTGC TTTCGACCTG CTATCAGGCG


 


1051
GATGCGCCCG CCGCCGTCCG CTATCCGCGC GGCACGGGTA CGGGCGCGCC


 


1101
GGTTTCAGAC GGCATGGAAA CCGTGGAAAT CGGCAAGGGC ATTATCCGCC


 


1151
GCGAAGGTGA GAAAACCGCC TTcatTGCCT TCGGCAGTAT GGTCGCCACC


 


1201
GCATTGGCGG TTGCCGAAAA ACTGAACGCC ACCGTCGCCG ATATGCGCTt


 


1251
cgtcaaacCG ATAGACGAAG AGTTGATTGT CCGCCTTGCC CGAAGCCAcg


 


1301
accGCATCGT TACCCTTGAA GAAAACGCCG AACAGGGCGG CGCAGGCGGC


 


1351
GCGGTCTTGG AAGTGTTGGC GAAACACGGC ATCTGCAAAC CCGTTTTGCT


 


1401
TTTGGGCGTT GCCGATACCG TAACCGAACA CGGCGATCCG AAAAAACTTT


 


1451
TGGACGATTT GGGTTTGAGT GCCGAAGCGG TGGAACGCCG GGTGCGCGAG


 


1501
TGGCTGCCGG ACCGTGATGC GGCAAATTAA






This corresponds to the amino acid sequence <SEQ ID 116; ORF 033.ng>:










g033.pep




1
MAAADKLLGG DRRSVAIIGD GAMTAGQAFE ALNCAGDMDV DLLVVLNDNE


 


51
MSISPNVGAL PKYLASNVVR DMHGLLSTVK AQTGKVLDKI PGAMEFAQKV


 


101
EHKIKTLAEE AEHAKQSLSL FENFGFRYTG PVDGHNVENL VDVLKDLRSR


 


151
KGPQLLHVIT KKGNGYKLAE NDPVKYHAVA NLPKEGGAQM PSEKEPKPAA


 


201
KPTYTQVFGK WLCDRAAADS RLVAITPAMR EGSGLVEFEQ RFPDRYFDVG


 


251
IAEQHAVTFA GGLACEGMKP VVAIYSTFLQ RAYDQLVHDI ALQNLPVLFA


 


301
VDRAGIVGAD GPTHAGLYDL SFLRCVPNMI VAAPSDENEC RLLLSTCYQA


 


351
DAPAAVRYPR GTGTGAPVSD GMETVEIGKG IIRREGEKTA FIAFGSMVAT


 


401
ALAVAEKLNA TVADMRFVKP IDEELIVRLA RSHDRIVTLE ENAEQGGAGG


 


451
AVLEVLAKHG ICKPVLLLGV ADTVTEHGDP KKLLDDLGLS AEAVERRVRE


 


501
WLPDRDAAN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 117>:










m033.seq




1
ATGGCGGCGG CAGACAAACT CTTGGGCAGC GACCGCCGCA GCGTCGCCAT


 


51
CATCGGCGAC GGCGCGATGA CGGCGGGGCA GGCGTTTGAA GCCTTGAATT


 


101
GCGCaG.CGA TATGGATGTr GATTTGCTrG TCGTCCTCAA CGACAACGAA


 


151
ATGTCGATTT CCCCCAACGT CGGCGCGCTG CCGAAATACC TTGCCAGCAA


 


201
CGTCGTGCGC GATATGCACG GCCTGTTGAG TACCGTCAAA GCGCAAACGG


 


251
GCAAGGTATT AGACAAAATA CCCGGCGCGA TGGAGTTTGC CCAAAAAGTC


 


301
GAACACAAAA TCAAAACCCT TGCCGAAGAA GCCGAACACG CCAAACAGTC


 


351
GCTGTCTTTG TTTGAAAACT TCGGCTTCCG CTACACCGGC CCCGTGGACG


 


401
GACACAACGT CGAAAATCTG GTGGACGTAT TGAAAGACTT GCGCAGCCGC


 


451
AAAGGCCCTC AGTTGCTGCA CGTCATCACC AAAAAGGGCA ACGGCTACAA


 


501
ACTCGCCGAA AACGACCCCG TCAAATACCA CGCCGTCGCC AACCTGCCTA


 


551
AAGAAAGCGC GGCGCAAATG CCGTCTGAAA AAGAACCCAA GCCCGCCGCC


 


601
AAACCGACCT ATACCCAAGT GTTCGGCAAA TGGCTGTGCG ACCGGGCGGC


 


651
GGCAGATTCC CGACTGGTTG CGATTACCCC CGCCATGCGC GAGGGCAGCG


 


701
GCTTGGTTGA GTTTGAACAA CGATTCCCCG ACCGCTATTT CGATGTCGGC


 


751
ATCGCCGAGC AGCACGCCGT TACCTTTGCC GGCGGTTTGG CTTGCGAAGG


 


801
GATGAAGCCC GTCGTGGCGA TTTATTCCAC CTTTTTACAA CGCGCCTACG


 


851
ACCAACTGGT GCACGACATC GCCCTGCAAA ACCTACCCGT TTTGTTTGCC


 


901
GTCGACCGCG CGGGCATCGT CGGCGCGGAC GGCCCGACCC ATGCCGGTCT


 


951
GTACGATTTG AGCTTTTTGC GCTGCGTGCC GAACATGATT GTCGCCGCGC


 


1001
CGAGCGATGA AAACGAATGC CGCCTGTTGC TTTCGACCTG CTATCAGGCA


 


1051
GACGCGCCCG CCGCCGTCCG CTATCCGCGC GGCACGGGTA CGGGCGCGCC


 


1101
GGTTTCAGAC GGCATGGAAA CCGTGGAAAT CGGCAAGGGC ATTATCCGCC


 


1151
GCGAAGGTGA GAAAACCGCA TTCATTGCCT TCGGCAGTAT GGTCGCCCCC


 


1201
GCATTGGCGG TTGCCGAAAA ACTGAACGCC ACCGTCGCCG ATATGCGCTT


 


1251
CGTCAAACCG ATAGACGAAG AGTTGATTGT CCGCCTTGCC CGAAGCCACG


 


1301
ACCGCATCGT TACCCTTGAA GAAAACGCCG AACAGGGCGG CGCAGGCGGC


 


1351
GCGGTGCTGG AAGTATTGGC GAAACACGGC ATCTGCAAAC CCGTTTTGCT


 


1401
TTTGGGCGTT GCCGATACCG TAACCGGACA CGGCGATCCG AAAAAACTTT


 


1451
TAGACGATTT GGGCTTGAGT GCCGAAGCGG TGGAACGGCG TGTGCGCGCG


 


1501
TGGCTGTCGG ATCGGGATGC GGCAAATTAA






This corresponds to the amino acid sequence <SEQ ID 118; ORF 033>:










m033.pep




1
MAAADKLLGS DRRSVAIIGD GAMTAGQAFE ALNCAXDMDV DLLVVLNDNE


 


51
MSISPNVGAL PKYLASNVVR DMHGLLSTVK AQTGKVLDKI PGAMEFAQKV


 


101
EHKIKTLAEE AEHAKQSLSL FENFGFRYTG PVDGHNVENL VDVLKDLRSR


 


151
KGPQLLHVIT KKGNGYKLAE NDPVKYHAVA NLPKESAAQM PSEKEPKPAA


 


201
KPTYTQVFGK WLCDRAAADS RLVAITPAMR EGSGLVEFEQ RFPDRYFDVG


 


251
IAEQHAVTFA GGLACEGMKP VVAIYSTFLQ RAYDQLVHDI ALQNLPVLFA


 


301
VDRAGIVGAD GPTHAGLYDL SFLRCVPNMI VAAPSDENEC RLLLSTCYQA


 


351
DAPAAVRYPR GTGTGAPVSD GMETVEIGKG IIRREGEKTA FIAFGSMVAP


 


401
ALAVAEKLNA TVADMRFVKP IDEELIVRLA RSHDRIVTLE ENAEQGGAGG


 


451
AVLEVLAKHG ICKPVLLLGV ADTVTGHGDP KKLLDDLGLS AEAVERRVRA


 


501
WLSDRDAAN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 119>:










a033.seq




1
ATGGCGGCGG CGGACAAACA GTTGGGCAGC GACCGCCGCA GCGTCGCCAT


 


51
CATCGGCGAC GGCGCGATGA CGGCGGGTCA GGCGTTTGAA GCCTTGAACT


 


101
GCGCGGGCGA TATGGATGTG GATTTGCTGG TCGTCCTCAA CGACAACGAA


 


151
ATGTCGATTT CCCCCAACGT CGGTGCGTTG CCCAAATACC TTGCCAGCAA


 


201
CGTCGTGCGC GATATGCACG GACTGTTGAG TACCGTCAAA GCGCAAACGG


 


251
GCAAGGTATT AGACAAAATA CCCGGCGCGA TGGAGTTTGC CCAAAAAGTC


 


301
GAACATAAAA TCAAAACCCT TGCCGAAGAA GCCGAACACG CCAAACAGTC


 


351
ACTGTCTTTG TTTGAAAACT TCGGCTTCCG CTATACCGGC CCCGTGGACG


 


401
GACACAACGT CGAAAATCTG GTCGATGTAT TGGAAGACCT GCGCGGACGC


 


451
AAAGGCCCGC AGCTTCTGCA CGTCATCACC AAAAAGGGCA ACGGCTACAA


 


501
ACTCGCCGAA AACGATCCCG TCAAATACCA CGCCGTCGCC AACCTGCCTA


 


551
AAGAAAGCGC GGCGCAAATG CCGTCTGAAA AAGAACCCAA GCCCGCCGCC


 


601
AAACCGACCT ATACCCAAGT GTTCGGCAAA TGGCTGTGCG ACCGGGCGGC


 


651
GGCAGATTCC CGACTGGTTG CGATTACCCC CGCCATGCGC GAGGGCAGCG


 


701
GCTTGGTTGA GTTTGAACAA CGATTCCCCG ACCGCTATTT CGATGTCGGC


 


751
ATCGCCGAGC AGCACGCCGT TACCTTTGCC GGCGGTTTGG CTTGCGAAGG


 


801
GATGAAGCCC GTCGTGGCGA TTTATTCCAC CTTTTTACAA CGCGCCTACG


 


851
ACCAACTGGT GCACGACATC GCCCTGCAAA ACCTGCCCGT TTTGTTTGCC


 


901
GTCGACCGCG CGGGCATCGT CGGCGCGGAC GGCCCGACCC ATGCCGGTTT


 


951
GTACGATTTA AGCTTTTTGC GCTGCATTCC GAATATGATT GTCGCCGCGC


 


1001
CGAGCGATGA AAATGAATGC CGCCTGCTGC TTTCGACCTG CTATCAGGCA


 


1051
GACGCGCCCG CCGCCGTCCG CTATCCGCGC GGCACGGGTA CGGGCGTGCC


 


1101
GGTTTCAGAC GGCATGGAAA CCGTGGAAAT CGGCAAGGGC ATTATCCGCC


 


1151
GCGAAGGTGA GAAAACCGCA TTCATTGCCT TCGGCAGTAT GGTCGCCCCT


 


1201
GCATTGGCGG TCGCCGGAAA ACTGAACGCC ACCGTCGCCG ATATGCGCTT


 


1251
CGTCAAACCG ATAGACGAAG AGTTGATTGT CCGCCTTGCC CGAAGCCACG


 


1301
ACCGCATCGT TACCCTTGAA GAAAACGCCG AACAGGGCGG CGCAGGCAGC


 


1351
GCGGTGCTGG AAGTGTTGGC GAAACACGGC ATCTGCAAAC CCGTCTTGCT


 


1401
TTTGGGCGTT GCCGATACCG TAACCGGACA CGGCGATCCG AAAAAACTTT


 


1451
TAGACGATTT GGGCTTGAGT GCCGAAGCGG TGGAACGGCG TGTGCGCGCG


 


1501
TGGCTGTCGG ATCGGGATGC GGCAAATTAA






This corresponds to the amino acid sequence <SEQ ID 120; ORF 033.a>:










a033.pep




1
MAAADKQLGS DRRSVAIIGD GAMTAGQAFE ALNCAGDMDV DLLVVLNDNE


 


51
MSISPNVGAL PKYLASNVVR DMHGLLSTVK AQTGKVLDKI PGAMEFAQKV


 


101
EHKIKTLAEE AEHAKQSLSL FENFGFRYTG PVDGHNVENL VDVLEDLRGR


 


151
KGPQLLHVIT KKGNGYKLAE NDPVKYHAVA NLPKESAAQM PSEKEPKPAA


 


201
KPTYTQVFGK WLCDRAAADS RLVAITPAMR EGSGLVEFEQ RFPDRYFDVG


 


251
IAEQHAVTFA GGLACEGMKP VVAIYSTFLQ RAYDQLVHDI ALQNLPVLFA


 


301
VDRAGIVGAD GPTHAGLYDL SFLRCIPNMI VAAPSDENEC RLLLSTCYQA


 


351
DAPAAVRYPR GTGTGVPVSD GMETVEIGKG IIRREGEKTA FIAFGSMVAP


 


401
ALAVAGKLNA TVADMRFVKP IDEELIVRLA RSHDRIVTLE ENAEQGGAGS


 


451
AVLEVLAKHG ICKPVLLLGV ADTVTGHGDP KKLLDDLGLS AEAVERRVRA


 


501
WLSDRDAAN*






m033/a033 98.4% identity over a 509 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 033 shows 98.4% identity over a 509 aa overlap with a predicted ORF (ORF 033.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 121>:










g034.seq




1
ATGAGCCGTT TATGGTTTTT TGCCGTAAAA AACATTATAA TCCGCCTTAT


 


51
TTACCTATTG CCCAAGGAGA CACAAATGGC ACTCGTATCC ATGCGCCAAC


 


101
TGCTTGACCA CGCCGCCGAA AACAGCTACG GCCTGCCCGC GTTCAACGTC


 


151
AACAACCTCG AACAAATGCG CGCCATTATG GAAGCCGCCG ACCAAGTCAA


 


201
CGCGCCCGTC ATCGTACAGG CGAGCGCAGG TGCGCGCAAA TACGcggGCG


 


251
CGCCGTTTTT GCGCCACCTG ATTCTGGCGG CAGTCGAAGA ATTTCCGCAC


 


301
ATCCCCGTCG TGATGCACCA AGACCACGGC GCATCGCCCG ACGTgtgCCA


 


351
ACGCTCCATC CAACTGGGCT TCTCCTCCGT GATGATGGAC GGCTCTTTGC


 


401
TCGAAGACGG CAAAACCCCT TCTTCTTACG AATACAACGT CAACGCCACC


 


451
CGTACCGTCG TCAACTTCTC CCACGCCTGC GGCGTGTCCG TCGAAGGCGA


 


501
AATCGGCGTA TTGGGCAACC TCGAAACCGG CGAAGCAGGC GAAGAAGACG


 


551
GAGTGGGCGC GGCAGGCAAA CTCTCACACG ACCAAATGCT CACCAGCGTT


 


601
GAAGATGCCG TGCGTTTCGT TAAAGATACC GGCGTTGACG CATTGGCGAT


 


651
TGCCGTCGGC ACCAGCCACG GCGCATACAA ATTCACCCGT CCGCCCACAG


 


701
GCGACGTATT GCGTATCGAC CGCATCAAGG AAATCCACCA AGCCCTGCCC


 


751
AATACACACA TCGTGATGCA CGgctCCAGC TCCGTTCCGC AAGAatgGCT


 


801
GAAAGTCATC AACGAATACG GCGGCAATAT CGGCGAAACC TACGGCGTGC


 


851
CGGTTGAAGA AATCGTCGAA GGCATCAAAC ACGGCGTGCG CAAAGTCAAC


 


901
ATCGATACCG ACCTGCGCCT CGCTTCCACC GGCGCGGTAC GCCGCTACCT


 


951
TGCCGAAAAC CCGTCCGACT TTGATCCGCG CAAATACTTG GGCAAAACCA


 


1001
TTGAAGCGAT GAAGCAAATC TGCCTCGACC GTTATCTTGC GTTCGGTTGC


 


1051
GAAGGTCAGG CAGGCAAAAT CAAACCTGTT TCGTTGGAAA AAATGGCAAG


 


1101
CCGTTATGCC AAGGGCGAAT TGAACCAAAT CGTCAAATAA






This corresponds to the amino acid sequence <SEQ ID 122. ORF 034.ng>:










g034.pep




1
MSRLWFFAVK NIIIRLIYLL PKETQMALVS MRQLLDHAAE NSYGLPAFNV


 


51
NNLEQMRAIM EAADQVNAPV IVQASAGARK YAGAPFLRHL ILAAVEEFPH


 


101
IPVVMHQDHG ASPDVCQRSI QLGFSSVMMD GSLLEDGKTP SSYEYNVNAT


 


151
RTVVNFSHAC GVSVEGEIGV LGNLETGEAG EEDGVGAAGK LSHDQMLTSV


 


201
EDAVRFVKDT GVDALAIAVG TSHGAYKFTR PPTGDVLRID RIKEIHQALP


 


251
NTHIVMHGSS SVPQEWLKVI NEYGGNIGET YGVPVEEIVE GIKHGVRKVN


 


301
IDTDLRLAST GAVRRYLAEN PSDFDPRKYL GKTIEAMKQI CLDRYLAFGC


 


351
EGQAGKIKPV SLEKMASRYA KGELNQIVK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 123>:









m034.seq (partial)










1
ATGAGCTGTT TATGGTTTTT TGCTGTAAAA AACATTATAA TCCGCCTTAT



 


51
TTACCTATTG CCCAAGGAGA CACAAATGGC ACTCGTATCC ATGCGCCAAC


 


101
TGCTTGATCA TGCTGCCGAA wACAGCTACG GCyTGCCGGC GTTCAACGTC


 


151
AACAACCTCG wACAGATGCG CGCCATCATG GAGGCTGCAG ACCAAGTCGA


 


201
CGCCCCCGTC ATCGTACAGG CGAGTGCCGG TGCGCGCAAA TATGCGGGTG


 


251
CGCCGTTTTT ACGCCACCTG ATTTTGGCGG CTGTCGAAGT ATTTCCACAC


 


301
ATCCCCGTCG TCATGCACCA AGACCACGGC GCATCACCCG ACGTGTGCCA


 


351
ACGCTCCATC CAACTGGGCT TCTCCTCTGT AATGATGGAC GGCTCGCTGA


 


401
TGGAAGACGG CAAAACCCCT TCTTCTTACG AATACAACGT CAACGCCACA


 


451
CGTACCGTGG TTAACTTCTC CCACGCTTGC GGCGTATCCG TTGAAGGCGA


 


501
AATCGGCGTA TTGGGCAACC TCGAAACCGG CGATGCAGGC GAAGAAGACG


 


551
GTGTAGGCGC AGTGGGCAAA CTTTCCCACG ACCAAATGCT GACCAGCGTC


 


601
GAAGATGCCG TATGTTTCGT TAAAGATACC GGCGTTGACG CATTGGCTAT


 


651
TGCCGTCGGC ACCAGCCACG GCGCATACAA ATTCACCCGT CCGCCCACAG


 


701
GCGATGTATT ACGTATCGAC CGCATCAAAG AAATCCACCA AGCCCTGCCC


 


751
AATACACACA TCGTGATGCA C...






This corresponds to the amino acid sequence <SEQ ID 124; ORF 034>:









m034.pep (partial)










1
MSCLWFFAVK NIIIRLIYLL PKETQMALVS MRQLLDHAAE XSYGLPAFNV



 


51
NNLXQMRAIM EAADQVDAPV IVQASAGARK YAGAPFLRHL ILAAVEVFPH


 


101
IPVVMHQDHG ASPDVCQRSI QLGFSSVMMD GSLMEDGKTP SSYEYNVNAT


 


151
RTVVNFSHAC GVSVEGEIGV LGNLETGDAG EEDGVGAVGK LSHDQMLTSV


 


201
EDAVCFVKDT GVDALAIAVG TSHGAYKFTR PPTGDVLRID RIKEIHQALP


 


251
NTHIVMH...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 125>:










a034.seq




1
ATGAGCCGTT TATGGTTTTT TGCCGCAAAA AACATTATAA TCCGCCTTAT



 


51
TTACCTATTG CCCAAGGAGA CACAAATGGC ACTCGTATCC ATGCGCCAAC


 


101
TGCTTGATCA TGCTGCCGAA AACAGCTACG GCCTGCCCGC GTTCAACGTC


 


151
AACAACCTCG AACAAATGCG CGCCATTATG GAAGCCGCCG ACCAAGTCAA


 


201
CGCGCCCGTC ATCGTACAGG CGAGCGCAGG TGCGCGCAAA TACGCGGGCG


 


251
CGCCGTTTTT GCGCCACCTG ATTTTGGCGG CTGTCGAAGA ATTTCCGCAC


 


301
ATCCCCGTCG TGATGCACCA AGACCACGGC GCATCGCCCG ACGTGTGCCA


 


351
ACGCTCCATC CAACTGGGCT TTTCCTCCGT GATGATGGAC GGCTCGCTGA


 


401
TGGAAGACGG CAAAACCCCT TCTTCTTATG AATACAACGT CAACGCCACC


 


451
CGTACCGTGG TTAATTTCTC CCACGCCTGC GGCGTATCCG TTGAAGGCGA


 


501
AATCGGCGTA TTGGGCAACC TCGAAACTGG CGAAGCCGGC GAAGAAGACG


 


551
GTGTAGGCGC AGTGGGCAAA CTTTCCCACG ACCAAATGCT CACCAGCGTC


 


601
GAAGATGCCG TGCGTTTCGT TAAAGATACC GGCGTTGACG CATTGGCGAT


 


651
TGCCGTCGGC ACCAGCCACG GCGCGTACAA ATTCACCCGT CCGCCCACAG


 


701
GCGACGTGTT GCGTATCGAC CGCATCAAAG AAATCCACCA AGCCCTGCCC


 


751
AATACACACA TCGTGATGCA CGGCTCCAGC TCCGTTCCGC AAGAATGGCT


 


801
GAAAGTCATC AACGAATACG GCGGCAATAT CGGCGAAACC TACGGCGTGC


 


851
CGGTTGAAGA AATCGTCGAA GGCATCAAAC ACGGCGTGCG TAAAGTCAAC


 


901
ATCGATACCG ACTTGCGCCT TGCTTCCACC GGCGCGGTAC GCCGCTACCT


 


951
TGCCGAAAAC CCGTCCGACT TCGATCCGCG CAAATATTTG AGCAAAACCA


 


1001
TTGAAGCGAT GAAGCAAATC TGCCTCGACC GCTACCTCGC GTTCGGTTGC


 


1051
GAAGGTCAGG CAGGCAAAAT CAAACCGGTT TCCTTGGAAA AAATGGCAAA


 


1101
CCGTTATGCC AAGGGCGAAT TGAACCAAAT CGTCAAATAA






This corresponds to the amino acid sequence <SEQ ID 126; ORF 034.a>:










a034.pep




1
MSRLWFFAAK NIIIRLIYLL PKETQMALVS MRQLLDHAAE NSYGLPAFNV



 


51
NNLEQMRAIM EAADQVNAPV IVQASAGARK YAGAPFLRHL ILAAVEEFPH


 


101
IPVVMHQDHG ASPDVCQRSI QLGFSSVMMD GSLMEDGKTP SSYEYNVNAT


 


151
RTVVNFSHAC GVSVEGEIGV LGNLETGEAG EEDGVGAVGK LSHDQMLTSV


 


201
EDAVRFVKDT GVDALAIAVG TSHGAYKFTR PPTGDVLRID RIKEIHQALP


 


251
NTHIVMHGSS SVPQEWLKVI NEYGGNIGET YGVPVEEIVE GIKHGVRKVN


 


301
IDTDLRLAST GAVRRYLAEN PSDFDPRKYL SKTIEAMKQI CLDRYLAFGC


 


351
EGQAGKIKPV SLEKMANRYA KGELNQIVK*






m034/a034 96.9% identity over a 257 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 034 shows 96.5% identity over a 257 aa overlap with a predicted ORF (ORF 034.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 127>:










g036.seq




1
ATGCTGAAGC CGTGTTTGGT ATACAGTGCC TGTGCGGCGG cgttgcCTGC



 


51
GCGGACTTCG AGCAGCAGGC GTTGCGTGCC TTCGGGCAGA TGTGCGTACC


 


101
AATATTCGAG CAGGGCGGAC GCAACGCCCC GTCGGCGGCA TTCGGGCGCG


 


151
GTGGCAATCA GGTGCAGTTC GGATTCGTCG GGCAGGTTCT GCCAAACGAT


 


201
AAAGGCGGCA ATCCTGCCGT CTTTTTCCGC AAGGAAAACC TGTTCGGACG


 


251
GCGAAACAAG CGCGGACTCA AATTGGCGTT GCGTCCACGC GGACGGGTTG


 


301
CAGACGGTAT CGAGCGCGGC CAGTGCGGCG CAGTCGGACG GTGAGGCTGG


 


351
GCGGATGTTC ATGTTCGTGC CTTCCGTTCC GCCTGTTCTT TGGCAGTCAG


 


401
GGCGATTTTG TTGCGGACGT AGAGCAGTTC GGCGTGTGCC GCGCCAGTTG


 


451
CGGGATAGCC GCCGCCGAGG GCGAGCGCGA GAAAATCGGC GGCGGTCGGC


 


501
ATATCGGGTT TGCCTGAGAA GGGCGGACGG TTTTCCAGTG CGAACGCACT


 


551
GCCGATGCCG TCTGAAAAGA CGTACCCCTC GGGGAGGGCA ATGTCTGCCG


 


601
CCCTACCGAC TTGATAATCG CTCAAACGGC GGCGGTTCAG CGTGTCGAAC


 


651
CACGCATAAA ACACTTCGCC CATACGCGCG TCCGCAGCGG CGAGTATGCA


 


701
GCTTTGCGGC GGCGGCAGCG AGGCGGCGGC ATCGAGCGTG GGGATGCCGA


 


751
TTAAAGGCGT GTCGAACGGC GTTGCCAAAC CTTGCGCCAC GCCGATGCCG


 


801
ATACGCAGTC CGGTAA






This corresponds to the amino acid sequence <SEQ ID 128; ORF 036.ng>:










g036.pep




1
MLKPCLVYSA CAAALPARTS SSRRCVPSGR CAYQYSSRAD ATPRRRHSGA



 


51
VAIRCSSDSS GRFCQTIKAA ILPSFSARKT CSDGETSADS NWRCVHADGL


 


101
QTVSSAASAA QSDGEAGRMF MFVPSVPPVL WQSGRFCCGR RAVRRVPRQL


 


151
RDSRRRGRAR ENRRRSAYRV CLRRADGFPV RTHCRCRLKR RTPRGGQCLP


 


201
PYRLDNRSNG GGSACRTTHK TLRPYARPQR RVCSFAAAAA RRRHRAWGCR


 


251
LKACRTALPN LAPRRCRYAV R*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 129>:










m036.seq




1
ATGCTGAAGC CGTGCGCCGT GTACAGTGCC TGTGCGGCGG TGTTGCCTGC



 


51
ACGGACTTCG AGCAGCAGGC GTTGCGTGTC TTCGGGCAGA TGTGTGAACC


 


101
AATATTCGAG CAGGGCGGAC GCAATTCCTT GGCGGCGGCA TTCGGGCGCG


 


151
GTGGCAATCA GGTGCAGTTC GGATTCGTCG GGCAGGTTCT GCCAAACGAT


 


201
AAAGGCGGCA ATCCCg.CGT CTTTTTCCGC AAGGAAAACC TGTTCGGACG


 


251
GCGAAACCAG TGCGGACTCA AATTGGCGTT GCGTCCATGC GGACGGGTTG


 


301
CAGACGGCAT CGAGTGCGGC CAGCTCCTCA CAATCGGCAC AAACGGCACG


 


351
GCGGATGTTC ACGGGCGCGC TCTCCGTTCG GCCTGTTCTT TGGCAGTCAG


 


401
GGCGATTTTG TTGCGGACGT AGAGCAAACC GGCGTGTGCG GCATGGACGG


 


451
CAGGATAACC GCCCTTGGCT GCCAATGCGA GAAAGTCGGC GGCAGTCGGC


 


501
ATATCCGGTC TGCCTGAGAA CGGCGGAGCT TCTTCCAGCG CGAACGCGCT


 


551
GCCTATGCCG TCTGAAAAGG CGCATCCCTC CGGCAGCCGG ATGTCTGCCG


 


601
CCCGCCCGAC CTGATAATCG CTCAAACGGT GGCAGTTCAG CGTATCGAAC


 


651
CATGCATAAA ACACTTCGCC CATACGAGCG TCCGTAGCGG CAAGGATGCA


 


701
GCTTTGCGGC GGCGGCAGCG AGGCGGCGGC ATCGAGCGAG GGTACGCCGA


 


751
TTAAGGGGGT ATCAAACGGC GTTGCCAAAC CCTGAGCTAC ACCGATGCCG


 


801
ATACGCAGTC CGGTAA






This corresponds to the amino acid sequence <SEQ ID 130; ORF 036>:










m036.pep




1
MLKPCAVYSA CAAVLPARTS SSRRCVSSGR CVNQYSSRAD AIPWRRHSGA



 


51
VAIRCSSDSS GRFCQTIKAA IPXSFSARKT CSDGETSADS NWRCVHADGL


 


101
QTASSAASSS QSAQTARRMF TGALSVRPVL WQSGRFCCGR RANRRVRHGR


 


151
QDNRPWLPMR ESRRQSAYPV CLRTAELLPA RTRCLCRLKR RIPPAAGCLP


 


201
PARPDNRSNG GSSAYRTMHK TLRPYERP*R QGCSFAAAAA RRRHRARVRR


 


251
LRGYQTALPN PELHRCRYAV R*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 131>:










a036.seq




1
ATGCTGAAGC CGTGCGCCGT GTACAGTGCC TGTGCGGCGG TGTTGCCTGC



 


51
ACGGACTTCG AGCAGCAGGC GTTGCGTGTC TTCGGGCAGA TGTGTGAACC


 


101
AATATTCGAG CAGGGCGGAC GCAATTCCTT GGCGGCGGCA TTCGGGCGCG


 


151
GTGGCAATCA GGTGCAGTTC GGATTCGTCG GGCAGGTTCT GCCAAACGAT


 


201
AAAGGCGGCA ATCCCGCCGT CTTTTTCCGC AAGGAAAACC TGTTCGGACG


 


251
GCGAAACCAG TGCGGACTCA AATTGGCGTT GCGTCCACGC GGACGGGTTG


 


301
CAGACGGCAT CGAGCGCGGC GAGTGCGGCG CAATCGGCAT AAACGGCGCG


 


351
GCGGATGTTC ACAGGCGCGC CCTCCGTTCC GCCTGTTCTT TGGCAGTCAA


 


401
GGCGATTTTG TTGCGGACGT AGAGCAGCTC GGCGTGTGCC GCAGCGACGG


 


451
CGGGAAAACC GCCTTCAGCC GCCAGATTGA GGAAGTCGGC GGCGGTCGGC


 


501
ATATCGGGTT TGCCTGAGAA GGGCGGACGG TTTTCCAGCG CGAACGCATT


 


551
GCCGATGCCG TCTGAAAAGG CGCATCCTTC CGGCAGCCGG ATGTCTGCCG


 


601
CCCGACCGAC CTGATAATCG CTCAAACGGC GGCGGTTCAG CGTGTCGAAC


 


651
CATGCATAAA ACACTTCGCC CATACGTGCG TCCGCAGCGG CAAGGATGCA


 


701
GCTTTGCGGC GGCGGCAGCG AGGCGGCGGC ATCGAGCGAG GGTACGCCGA


 


751
TTAAAGGAGT ATCAAACGGC GTTGCCAAAC CTTGCGCCAC GCCGATGCCG


 


801
ATACGCAGTC CCGTAA






This corresponds to the amino acid sequence <SEQ ID 132; ORF 036.a>:










a036.pep




1
MLKPCAVYSA CAAVLPARTS SSRRCVSSGR CVNQYSSRAD AIPWRRHSGA



 


51
VAIRCSSDSS GRFCQTIKAA IPPSFSARKT CSDGETSADS NWRCVHADGL


 


101
QTASSAASAA QSA*TARRMF TGAPSVPPVL WQSRRFCCGR RAARRVPQRR


 


151
RENRLQPPD* GSRRRSAYRV CLRRADGFPA RTHCRCRLKR RILPAAGCLP


 


201
PDRPDNRSNG GGSACRTMHK TLRPYVRPQR QGCSFAAAAA RRRHRARVRR


 


251
LKEYQTALPN LAPRRCRYAV P*






m036/a036 85.6% identity over a 270 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 036 shows 74.9% identity over a 271 aa overlap with a predicted ORF (ORF 036.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 133>:










m036-1.seq




1
ATGCTGAAGC CGTGCGCCGT GTACAGTGCC TGTGCGGCGG TGTTGCCTGC



 


51
ACGGACTTCG AGCAGCAGGC GTTGCGTGTC TTCGGGCAGA TGTGTGAACC


 


101
AATATTCGAG CAGGGCGGAC GCAATTCCTT GGCGGCGGCA TTCGGGCGCG


 


151
GTGGCAATCA GGTGCAGTTC GGATTCGTCG GGCAGGTTCT GCCAAACGAT


 


201
AAAGGCGGCA ATCCCGCCGT CTTTTTCCGC AAGGAAAACC TGTTCGGACG


 


251
GCGAAACCAG TGCGGACTCA AATTGGCGTT GCGTCCATGC GGACGGGTTG


 


301
CAGACGGCAT CGAGTGCGGC CAGCTCCTCA CAATCGGCAC AAACGGCACG


 


351
GCGGATGTTC ACGGGCGCGC TCTCCGTTCG GCCTGTTCTT TGGCAGTCAG


 


401
GGCGATTTTG TTGCGGACGT AGAGCAAACC GGCGTGTGCG GCATGGACGG


 


451
CAGGATAACC GCCCTTGGCT GCCAATGCGA GAAAGTCGGC GGCAGTCGGC


 


501
ATATCCGGTC TGCCTGAGAA CGGCGGAGCT TCTTCCAGCG CGAACGCGCT


 


551
GCCTATGCCG TCTGAAAAGG CGCATCCCTC CGGCAGCCGG ATGTCTGCCG


 


601
CCCGCCCGAC CTGATAATCG CTCAAACGGT GGCAGTTCAG CGTATCGAAC


 


651
CATGCATAAA ACACTTCGCC CATACGAGCG TCCGTAG






This corresponds to the amino acid sequence <SEQ ID 134; ORF 0036-1>:










m036-1.pep




1
MLKPCAVYSA CAAVLPARTS SSRRCVSSGR CVNQYSSRAD AIPWRRHSGA



 


51
VAIRCSSDSS GRFCQTIKAA IPPSFSARKT CSDGETSADS NWRCVHADGL


 


101
QTASSAASSS QSAQTARRMF TGALSVRPVL WQSGRFCCGR RANRRVRHGR


 


151
QDNRPWLPMR ESRRQSAYPV CLRTAELLPA RTRCLCRLKR RIPPAAGCLP


 


201
PARPDNRSNG GSSAYRTMHK TLRPYERP*






m036-1/g036 76.8% identity in 228 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 135>:










g038.seq




1
ATGACTGATT TCCGCCAAGA TTTCCTCAAA TTCTCCCTCG CCCAAAATGT



 


51
TTTGAAATTC GGCGAATTTA CCACCAAAGC CGGACGGCGG TCGCCCTATT


 


101
TCTTCAATGC CGGCCTCTTC AACGACGGCG CGTCCACGCT GCAACTGGCA


 


151
AAATTCTATG CACAATCCAT CATTGAAAGC GGCATCCGAT TCGATATGCT


 


201
GTTCGGCCCC GCCTACAAAG GCATTATTTT GGCGGCGGCA ACCGCGATGA


 


251
TGCTGGCGGA AAAAGGCGTG AACGTCCCGT TTGCCTACAA CCGCAAAGAA


 


301
GCCAAAGACC GCGGCGAAGG CGGCGTGTTG GTCGGCGCGC CGCTTAAAGG


 


351
GCGCGTGCTG ATTATCGACG ACGTGATTTC CGCCGGCACA TCCGTACGCG


 


401
AATCAATCAA ACTGATTGAA GCGGAGGGTG CAACCCCCGC CGGTGTCGCC


 


451
ATCGCGCTCG ACCGCATGGA AAAAGGCACG GGTAAATTGT CCGCCGTTCA


 


501
GGAAGTGGAA AAACAATACG GCCTGCCCGT CGCCCCCATC GCCAGCCTGA


 


551
ACGATTTGTT TATCCTGTTG CAAAACAACC CCGAATTCGG ACAGTTCCTC


 


601
GAACCCGTCC GCACCTACCG CCGGCAGTAC GGCGTAGAAT AA






This corresponds to the amino acid sequence <SEQ ID 136; ORF 038.ng>:










g038.pep




1
MTDFRQDFLK FSLAQNVLKF GEFTTKAGRR SPYFFNAGLF NDGASTLQLA



 


51
KFYAQSIIES GIRFDMLFGP AYKGIILAAA TAMMLAEKGV NVPFAYNRKE


 


101
AKDRGEGGVL VGAPLKGRVL IIDDVISAGT SVRESIKLIE AEGATPAGVA


 


151
IALDRMEKGT GKLSAVQEVE KQYGLPVAPI ASLNDLFILL QNNPEFGQFL


 


201
EPVRTYRRQY GVE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 137>:










m038.seq




1
ATGACCGATT TCCGCCAAGA TTTCCTCAAA TTCTCCCTCG CCCAAAATGT



 


51
TTTGAAATTC GGCGAATTTA CCACCAAGGC AGGACGGCGG TCGCCCTATT


 


101
TCTTCAATGC CGGCCTCTTT AACGACGGCT TGTCCACGCT GCAACTGGCA


 


151
AAATTTTACG CACAATCCAT CATTGAAAGC GGCATCCGAT TCGATATGCT


 


201
GTTCGGTCCC GCCTACAAAG GCATTATTTT GGCGGCGGCA ACCGCGATGA


 


251
TGCTGGCGGA AAAAGGCGTG AACGTCCCGT TTGCCTACAA CCGCAAAGAA


 


301
GCCAAAGACC ACGGCGAAGG CGGCGTGTTG GTCGGCGCGC CGCTTAAAGG


 


351
GCGCGTGCTG ATTATCGACG ACGTGATTTC CGCCGGCACA TCCGTACGCG


 


401
AATCGATCAA ACTGATTGAA GCGGAGGGTG CAACCCCcGC CGGTGTCGCC


 


451
ATCGCGCTCG ATCGCATGGA AAAAGGCACG GGTGAATTGA GCGCGGTTCA


 


501
GGAAGTGGAr AAACAATACG GkCTGCCCGT CGCCCCCATC GCCAGCCTGA


 


551
ACGATTTGTT TATTCTGTTG CAAAACAACC CCGAATTCGG ACAGTTCCTC


 


601
GAACCCGTCC GAGCCTACCG TCGGCAGTAC GGCGTAGAAT AA






This corresponds to the amino acid sequence <SEQ ID 138; ORF 038>:










m038.pep




1
MTDFRQDFLK FSLAQNVLKF GEFTTKAGRR SPYFFNAGLF NDGLSTLQLA



 


51
KFYAQSIIES GIRFDMLFGP AYKGIILAAA TAMMLAEKGV NVPFAYNRKE


 


101
AKDHGEGGVL VGAPLKGRVL IIDDVISAGT SVRESIKLIE AEGATPAGVA


 


151
IALDRMEKGT GELSAVQEVE KQYGLPVAPI ASLNDLFILL QNNPEFGQFL


 


201
EPVRAYRRQY GVE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 139>:










a038.seq




1
ATGACCGATT TCCGCCAAGA TTTCCTCAAA TTCTCCCTCG CCCAAAATGT



 


51
TTTGAAATTC GGCGAATTCA CCACCAAAGC CGGACGGCGG TCGCCCTATT


 


101
TCTTCAATGC CGGCCTCTTT AACGACGGCT TGTCCACGCT GCAACTGGCA


 


151
AAATTTTACG CACAATCCAT CATTGAAAGC GGCATCCGAT TCGATATGCT


 


201
GTTCGGCCCC GCCTACAAAG GCATTATTTT GGCGGCGGCA ACCGCGATGA


 


251
TGCTGGCGGA AAAAGGCGTG AACGTCCCGT TTGCCTACAA CCGCAAAGAA


 


301
GCCAAAGACC ACGGCGAAGG CGGCGTGTTG GTCGGCGCGC CGCTTAAAGG


 


351
GCGCGTGCTG ATTATCGACG ACGTGATTTC CGCCGGCACA TCCGTACGCG


 


401
AATCGATCAA ACTGATTGAA GCGGAGGGTG CAACCCCCGC CGGTGTCGCC


 


451
ATCGCGCTCG ACCGCATGGA AAAAGGCACG GGTGAATTGA GCGCGGTTCA


 


501
GGAAGTGGAA AAACAATACG GCCTGCCCGT CGCCCCCATC GCCAGCCTGA


 


551
ACGATTTGTT TATTCTGTTG CAAAACAACC CCGAATTCGG ACAGTTCCTC


 


601
GAACCCGTCC GAGCCTACCG TCGGCAGTAC GGCGTAGAAT AA






This corresponds to the amino acid sequence <SEQ ID 140; ORF 038.a>:










a038.pep




1
MTDFRQDFLK FSLAQNVLKF GEFTTKAGRR SPYFFNAGLF NDGLSTLQLA


 


51
KFYAQSIIES GIRFDMLFGP AYKGIILAAA TAMMLAEKGV NVPFAYNRKE


 


101
AKDHGEGGVL VGAPLKGRVL IIDDVISAGT SVRESIKLIE AEGATPAGVA


 


151
IALDRMEKGT GELSAVQEVE KQYGLPVAPI ASLNDLFILL QNNPEFGQFL


 


201
EPVRAYRRQY GVE*






m038/a038 100.0% identity over a 213 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 038 shows 98.1% identity over a 213 aa overlap with a predicted ORF (ORF 038.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 141>:










g039.seq




1
ATGCCGTCCG AACCACCTGC CGCTTCAGAC GGCATCAAAC CGACACACAC


 


51
CGAGAAAACA TCATGCCCGC CTGTTTCTGT CCGCACTGCA AAACCCGCCT


 


101
CTGGGTCAAA GAAAcccagC TCAAcgtCgC ccaagGCTTC GTCGTCTgcc


 


151
aaAAAtgcga agGGCTgttt aaAgccaaaG accAtctggc aaGcacGAAA


 


201
gaacctatat tcaacgattg gcccgaagct gtttcgggat gTcaaaCTCG


 


251
TCcaccgcaT cggcacgcac gccattagca aGAaacagat gtcccgcgac


 


301
gaaatCgccg atatcctcaa cggcggtaca acCCTGCACG ATACGCCGCC


 


351
CGCAACCGCC GCTGCCGCac ctGCCGCCGC ACCGCaggTT TCCGTACCGC


 


401
CCGCCCGTCA GGAAGGGCTC AACTGGACTA TTGCAACCCT GTTCGCACTT


 


451
ATCGTCCTCA TTATGCAGCT TTCCTACCTC TTCATCCTAT GA






This corresponds to the amino acid sequence <SEQ ID 142; ORF 039.ng>:










g039.pep




1
MPSEPPAASD GIKPTHTEKT SCPPVSVRTA KPASGSKKPS STSPKASSSA


 


51
KNAKGCLKPK TIWQARKNLY STIGPKLFRD VKLVHRIGTH AISKKQMSRD


 


101
EIADILNGGT TLHDTPPATA AAAPAAAPQV SVPPARQEGL NWTIATLFAL


 


151
IVLIMQLSYL FIL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 143>:










m039.seq




1
ATGCCGTCCG AACCGCCTTA CGCCTCAGAC GGCATCAAAC CTGACACACA


 


51
CGAGGAAATA CCATGCCCGC CTGTTTCTGC CCCCACTGCA AAACCCGTCT


 


101
CTGGGTCAAA GAAACCCAAC TCAATGTCGC CGnnnnnnnn nnnnnnnnnn


 


151
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


201
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnCCC GAGGCTGTTT


 


251
CGGATGTCAA ACTCGTTCAC CGTATCGGCA CGCGCGCCAT CGGCAAGAAA


 


301
CAGATTTCCC GTGACGAAAT CGCCGGCATC CTCAACGGCG GTACAACCCA


 


351
GCCCGATATT CCGCCCGCAA CCGCCGCCAC CCCTGCTGCC GCACCGCAGG


 


401
TTACCGTACC GCCCGCCGCG CCCGCCCGTC AGGATGGGTT CAACTGGACG


 


451
ATTGCAACCC TGTTTGCCCT TATCGTCCTC ATTATGCAGC TTTCCTACCT


 


501
CGTCATCCTA TGA






This corresponds to the amino acid sequence <SEQ ID 144; ORF 039>:










m039.pep




1
MPSEPPYASD GIKPDTHEEI PCPPVSAPTA KPVSGSKKPN SMSPXXXXXX


 


51
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXP EAVSDVKLVH RIGTRAIGKK


 


101
QISRDEIAGI LNGGTTQPDI PPATAATPAA APQVTVPPAA PARQDGFNWT


 


151
IATLFALIVL IMQLSYLVIL *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 145>:










a039.seq




1
ATGCCGTCTG AACCGCCTTA CGCCTCAGAC GGCATCAAAC CTGACACACA


 


51
CGAGGAAATA CCATGCCCGC CTGTTTCTGC CCCCACTGCA AAACCCGTCT


 


101
CTGGGTCAAA GAAACCCAAC TCAATGTCGC CCAAGGCTTC GTCGTCTGCC


 


151
AAAAATGCGA AGGAATGTTT AAAGCCAAAG ACCATCTGGC AAGCACGAAA


 


201
GAACCCATAT TCAACGATT. TGCCCGAAGC TGTTTCGGAT GTCAAACTCG


 


251
TTCACCGCAT CGGCACGAGC GCCATCGGCA AGAAACAGAT TTCCCGTGAC


 


301
GAAATCGCCG GCATCCTCAA CGGCGGCACA ACCCAGCCCG ATATTCCGCC


 


351
CGCAACCGCC GCCACCCCTG CTGCCGCACC GCAGGTTACC GTACCGCCCG


 


401
CCGCGCCCGC CCGTCAGGAT GGGTTCAACT GGACGATTGC AACCCTGTTT


 


451
GCCCTTATCG TCCTCATTAT GCAGCTTTCC TACCTCGTCA TCCTATGA






This corresponds to the amino acid sequence <SEQ ID 146; ORF 039.a>:










a039.pep




1
MPSEPPYASD GIKPDTHEEI PCPPVSAPTA KPVSGSKKPN SMSPKASSSA


 


51
KNAKECLKPK TIWQARKNPY STIXPEAVSD VKLVHRIGTS AIGKKQISRD


 


101
EIAGILNGGT TQPDIPPATA ATPAAAPQVT VPPAAPARQD GFNWTIATLF


 


151
ALIVLIMQLS YLVIL*






m039/a039 79.4% identity over a 170 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 039 shows 60.8% identity over a 171 aa overlap with a predicted ORF (ORF 039.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 147>:










g040.seq




1
ATGAACGCGC CCGACAGCTT TGTCGCCCAC TTCCGCGAAG CCGCCCCCTA


 


51
CATCCGCCAA ATGCGCGGCA CGACACTGGT CGCCGGCATA GAcggCCGCC


 


101
TGCTCGAAGG CGGCACCTTA AATAAGCTCG CCGCCGACAT CGGGCTGTTG


 


151
TCGCAACTGG GCATCCGACT CGTCCTCATC CACGGCGCGT ACCACTTCCT


 


201
CGAccgCCTC GCCGCCGCGC AAGgccGCAC GCCGCATTAT TGCCGgggtt


 


251
tGCGCGTTAC CGACGaAACc tcGctcgGAC AGGCGCAGCA GtttGCCGGC


 


301
AccgTCCGCA GCCGTTTTGA agcCGCATTG tgcggcagCG tttcaggatt


 


351
cgcgCGCGCG CCTTCCGTCC CGCTCGTAtc gggcaacttc ctgacCGCCC


 


401
GTCcgatggg cgtgattgac ggaACCGata tggaatacgc gggggttatc


 


451
cgcaaaaccg ACACCGCCGC CCTCCGTTTC CAACTCGACG CGGGCAATAT


 


501
CGTCTGGATG CCGCCGCTCG GGCATTCCTA CGGCGGCAAA ACCTTCAATC


 


551
TCGATATGGT GCAGGCCGCC GCTTCCGTCG CCGTCTCGCT TCAGGCCGAA


 


601
AAACTCGTTT ACCTGACCCT TTCAGACGGC ATTTCCCGCC CCGACGGCAC


 


651
GCTCGCCGAA ACCCTCTCGG CACAGGAAGC GCAATCGCTG GCGGAACACG


 


701
CCGCCAGCGA AACCCGACGA CTGATTTCGT CCGCCGTTGC CGCGCTCGAA


 


751
GGCGGCGTGC ATCGCGTCCA AATCCTCAAC GGGGCCGCCG ACGGCAGCCT


 


801
GCTGCAAGAA CTCTTCACCC GCAACGGCAT CGGCACGTCC ATTGCCAAAG


 


851
AAGCCTTCGT CTCCATCCGG CAGGCGCACA GCGGCGACAT CCCGCACATC


 


901
GCCGCCCTCA TCCGCCCGCT GGAAGAACAG GGCGTCCTAT TGCACCGCAG


 


951
CCGCGAATAC CTCGAAAACC ACATTTCCGA ATTTTCCATC CTCGAACACG


 


1001
ACGGCGACCT GTACGGCTGT GCCGCACTCA AAACCTTTGC CGAAGCCGAT


 


1051
TGCGGCGAAA TCGCCTGCCT TGCCGTCTCG CCGCAGGCAC AGGACGGCGg


 


1101
ctACGGCGAA CGCCTGCTTG CCCACATTAT CGATAAGGCG CGCGGCATAG


 


1151
GCATAAGCAG GCTGTTCGCA CTGTCCACAA ATACCGGCGA ATGGTTTGCC


 


1201
GAACGCGGCT TTCAGACGGC ATCGGAAGAC GAGCTGCCCG AAACGCGGCG


 


1251
CAAAGACTAC CGCAGCAACG GACGAAACCC GCATATTCTG GTGCGTCGCC


 


1301
TGCACCGCTG A






This corresponds to the amino acid sequence <SEQ ID 148; ORF 040.ng>:










g040.pep




1
MNAPDSFVAH FREAAPYIRQ MRGTTLVAGI DGRLLEGGTL NKLAADIGLL


 


51
SQLGIRLVLI HGAYHFLDRL AAAQGRTPHY CRGLRVTDET SLGQAQQFAG


 


101
TVRSRFEAAL CGSVSGFARA PSVPLVSGNF LTARPMGVID GTDMEYAGVI


 


151
RKTDTAALRF QLDAGNIVWM PPLGHSYGGK TFNLDMVQAA ASVAVSLQAE


 


201
KLVYLTLSDG ISRPDGTLAE TLSAQEAQSL AEHAASETRR LISSAVAALE


 


251
GGVHRVQILN GAADGSLLQE LFTRNGIGTS IAKEAFVSIR QAHSGDIPHI


 


301
AALIRPLEEQ GVLLHRSREY LENHISEFSI LEHDGDLYGC AALKTFAEAD


 


351
CGEIACLAVS PQAQDGGYGE RLLAHIIDKA RGIGISRLFA LSTNTGEWFA


 


401
ERGFQTASED ELPETRRKDY RSNGRNPHIL VRRLHR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 149>:










m040.seq




1
ATGAGCGCGC CCGACCTCTT TGTCGCCCAC TTCCGCGAAG CCGTCCCCTA


 


51
CATCCGCCAA ATGCGCGGCA AAACGCTGGT CGCCGGCATA GACGACCGCC


 


101
TGCTCGAAGG TGATACCTTA AACAAGCTCG CCGCCGACAT CGGGCTGTTG


 


151
TCGCAACTGG GCATCAGGCT CGTCCTCATC CACGGCGCGC GCCACTTCCT


 


201
CGACCGCCAC GCCGCCGCTC AAGGCCGCAC GCCGCATTAT TGCCGGGGCT


 


251
TGCGCGTTAC CGACGAAACC TCGCTCGAAC AGGCGCAgCA GTTTGCCGGC


 


301
ACCGTCCGCA GCCGTTTTGA AGCCGCATTG TGCGGCAGCG TTTCCGGGTT


 


351
CGCGCGCGCG CCTTCCGTCC CGCTCGTATC GGGCAACTTC CTGACCGCCC


 


401
GTCCGATAGG TGTGATTGAC GGAACCGATA TGGAATACGC GGGCGTTATC


 


451
CGCAAAACCG ACACCGCCGC CCTCCGTTTC CAACTCGACG CGGGCAATAT


 


501
CGTCTGGCTG CCGCCGCTCG GACATTCCTA CAGCGGCAAG ACCTTCTATC


 


551
TCGATATGCT TCAAACCGCC GCCTCCGCCG CCGTCTCGCT TCAGGCCGAA


 


601
AAACTCGTTT ACCTGACCCT TTCAGACGGC ATTTCCCGCC CCGACGGCAC


 


651
GCTCGCCGAA ACCCTCTCGG CACAGGAAGC GCAATCGCTG GCGGAACACG


 


701
CCGGCGGGCA AACGCGACGG CTGATTTCGT CCGCCGAACT CTTCACCCGC


 


751
AACGGCATCG GCACGTCCAT TGCCAAAGAA GCCTTCGTCT CCATCCGGCA


 


801
rGCGCAywgG G.CGACATCC CGCACATCGC CGCCCTCATC CGCCCGCTGG


 


851
AAGAACAGGG CATCCTGCTG CACCGCAs.c GCGAATACCT CGAAAACCAC


 


901
ATTTCCGAAT TTTCCATCCT CGAACACGAC GGCAACCTGT ACGGTTGCGC


 


951
CGCCCTGAAA ACCTTTGCCG AAGCCGATTG CGGCGAAATC GCCTGCCTTG


 


1001
CCGTCTCGCC GCag.cACAG GACGGCGGCT ACGGCGAACG CnTGCTTGCC


 


1051
CACATTATCG ATAAGGCGCG CGGCATAGGC ATAAGCAGGC TGTTCGCACT


 


1101
GTCCACAAAT ACCGGCGAAT GGTTTGCCGA ACGCGGCTTT CAGACGGCAT


 


1151
CGGAAGACGA GTTGCCCGAA ACGCGGCGCA AAGACTACCG CAGCAACGGA


 


1201
CGGAACTCGC ATATTCTGGT ACGTCGCCTG CACCGCTGA






This corresponds to the amino acid sequence <SEQ ID 150; ORF 040>:










m040.pep




1
MSAPDLFVAH FREAVPYIRQ MRGKTLVAGI DDRLLEGDTL NKLAADIGLL


 


51
SQLGIRLVLI HGARHFLDRH AAAQGRTPHY CRGLRVTDET SLEQAQQFAG


 


101
TVRSRFEAAL CGSVSGFARA PSVPLVSGNF LTARPIGVID GTDMEYAGVI


 


151
RKTDTAALRF QLDAGNIVWL PPLGHSYSGK TFYLDMLQTA ASAAVSLQAE


 


201
KLVYLTLSDG ISRPDGTLAE TLSAQEAQSL AEHAGGQTRR LISSAELFTR


 


251
NGIGTSIAKE AFVSIRQAHX XDIPHIAALI RPLEEQGILL HRXREYLENH


 


301
ISEFSILEHD GNLYGCAALK TFAEADCGEI ACLAVSPQXQ DGGYGERXLA


 


351
HIIDKARGIG ISRLFALSTN TGEWFAERGF QTASEDELPE TRRKDYRSNG


 


401
RNSHILVRRL HR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 151>:










a040.seq




1
ATGATCGTGC CCGACCTCTT TGTCGCCCAC TTCCGCGAAG CCGCCCCCTA


 


51
CATCCGCCAA ATGCGCGGCA AAACGCTGGT CGCCGGCATA GACGACCGCC


 


101
TGCTCGAAGG TGATACCTTA AACAAGTTCG CCGCCGACAT CGGGCTTTTG


 


151
TCGCAACTGG GCATCAGGCT CGTCCTCATC CACGGCGCGC GCCACTTCCT


 


201
CGACCGCCAC GCCGCCGCGC AAGGCCGCAC GCCGCATTAT TGCCGGGGCT


 


251
TGCGCGTTAC CGACGAAACC TCGCTCGAAC AGGCGCAGCA GTTTGCCGGC


 


301
ACCGTCCGCA GCCGTTTTGA AGCCGCATTG TGCGGCAGCG TTTCCGGGTT


 


351
CGCGCGCGCG CCTTCCGTCC CGCTCGTATC GGGCAACTTC CTGACCGCCC


 


401
GTCCGATAGG TGTGATTGAC GGAACCGATA TGGAATACGC GGGCGTTATC


 


451
CGCAAAACCG ACACCGCCGC CCTCCGTTTC CAACTCGACG CGGGCAATAT


 


501
CGTCTGGCTG CCGCCGCTCG GACATTCCTA CAGCGGCAAG ACCTTCCATC


 


551
TCGATATGCT TCAAACCGCC GCCTCCGTCG CCGTCTCGCT TCAGGCCGAA


 


601
AAACTCGTTT ACCTGACCCT TTCAGACGGC ATTTCCCGCC CCGACGGCAC


 


651
GCTCGCCGTA ACCCTCTCGG CACAGGAAGC GCAATCGCTG GCGGAACACG


 


701
CCGGCGGCGA AACGCGACGG CTGATTTCGT CCGCCGTTGC CGCGCTCGAA


 


751
GGCGGCGTGC ATCGCGTCCA AATCCTCAAC GGAGCCGCCG ACGGCAGCCT


 


801
GCTGCAAGAA CTCTTCACCC GCAACGGCAT CGGCACGTCC ATTGCCAAAG


 


851
AAGCCTTCGT CTCCATCCGG CAGGCGCACA GCGGCGACAT CCCGCACATT


 


901
GCCGCCCTCA TCCGCCCGCT GGAAGAACAG GGCATCCTGC TGCACCGCAG


 


951
CCGCGAATAC CTCGAAAACC ACATTTCCGA ATTTTCCATC CTCGAACACG


 


1001
ACGGCAACCT GTACGGTTGC GCCGCCCTGA AAACCTTTGC CGAAGCCGAT


 


1051
TGCGGCGAAA TCGCCTGCCT TGCCGTCTCG CCGCAGGCAC AGGACGGCGG


 


1101
CTACGGCGAA CGCCTGCTTG CCCACATTAT CGATAAGGCG CGCGGCATAG


 


1151
GCATAAGCAG GCTGTTCGCA CTGTCCACAA ATACCGGCGA ATGGTTTGCC


 


1201
GAACGCGGCT TTCAGACGGC ATCGGAAGAC GAGTTGCCCG AAACGCGGCG


 


1251
CAAAGACTAC CGCAGCAACG GACGGAACTC GCATATTCTG GTGCGTCGCC


 


1301
TGCACCGCTG A






This corresponds to the amino acid sequence <SEQ ID 152; ORF 040.a>:










a040.pep




1
MIVPDLFVAH FREAAPYIRQ MRGKTLVAGI DDRLLEGDTL NKFAADIGLL


 


51
SQLGIRLVLI HGARHFLDRH AAAQGRTPHY CRGLRVTDET SLEQAQQFAG


 


101
TVRSRFEAAL CGSVSGFARA PSVPLVSGNF LTARPIGVID GTDMEYAGVI


 


151
RKTDTAALRF QLDAGNIVWL PPLGHSYSGK TFHLDMLQTA ASVAVSLQAE


 


201
KLVYLTLSDG ISRPDGTLAV TLSAQEAQSL AEHAGGETRR LISSAVAALE


 


251
GGVHRVQILN GAADGSLLQE LFTRNGIGTS IAKEAFVSIR QAHSGDIPHI


 


301
AALIRPLEEQ GILLHRSREY LENHISEFSI LEHDGNLYGC AALKTFAEAD


 


351
CGEIACLAVS PQAQDGGYGE RLLAHIIDKA RGIGISRLFA LSTNTGEWFA


 


401
ERGFQTASED ELPETRRKDY RSNGRNSHIL VRRLHR*






m040/a040 91.5% identity in 436 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 040 shows 88.3% identity over a 436 aa overlap with a predicted ORF (ORF 040.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 153>:










g041.seq




1
ATGAGTTCGC CCAAACACAT CGGCTTGCAG GGCGGCAGCA ACGGCGGCCT


 


51
GATTACCGCC GCCGCCTTCG TGCGCGAACC GCAAAGCATC GGTGCGCTGG


 


101
TGTGCGAAGT ACCGCTGACC GATATGATCC GTTATCCGCT GCTGTCCGCC


 


151
GGTTCAAGTT GGACGGACGA ATACGGCAAT CCGCAGAAAT ACGAAGCCTG


 


201
CAAACGCCGG CTGGGCGAAT TGTCGCCGTA TCACAATCTT TCAGACGGCA


 


251
TCGATTATCC GCCCGCACTC ATTACCACCA GCCTCAGCGA CGACCGCGTC


 


301
CATCCCGCCC ACGCGCTCAA ATTCTACGCC AAACTGCGCG AAACCTCGCC


 


351
GCAATCTTGG CTCTACTCGC CTGACGGCGG CGGCCATACC GGCAACGGCA


 


401
CCCAACGCGA ATCCGCCGAC AAACTCGCCT GCGTGTTGCT GTTTTTGAAA


 


451
GAATTTTTGG GATAA






This corresponds to the amino acid sequence <SEQ ID 154; ORF 041.ng>:










g041.pep




1
MSSPKHIGLQ GGSNGGLITA AAFVREPQSI GALVCEVPLT DMIRYPLLSA


 


51
GSSWTDEYGN PQKYEACKRR LGELSPYHNL SDGIDYPPAL ITTSLSDDRV


 


101
HPAHALKFYA KLRETSPQSW LYSPDGGGHT GNGTQRESAD KLACVLLFLK


 


151
EFLG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 155>:










m041.seq




1
ATCAGTTCGC CCGAACACAT CGGCTTGCAG GGCGGCAGCA ACGGCGGACT


 


51
GATTACTGCC GCCGCCTTCG TGCGCGAACC GCAAAGCATC GGCGCGCTGG


 


101
TGTGCGAAGT GCCGCTGACC GACATGATCC GTTATCCGCT GCTCTCCGCC


 


151
GGTTCAAGCT GGACAGACGA ATACGGCAAT CCGCAAAAAT ACGAAGTCTG


 


201
CAAACGCCGG TTGGGCGAAT TGTCGCCGTA TCACAATCTT TCAGACGGCA


 


251
TCGATTATCC GCCCGCGCTC ATTACCACCA GCCTGTCCGA CGATCGCGTC


 


301
CATCCCGCCC ACGCGCTCAA GTTCTACGCC AAACTGCGCG AAACCTCCGC


 


351
GCAATCTTGG CTCTACTCGC CTGACGGCGG CGGCCATACC GGCAACGGCA


 


401
CCCAACGCGA ATCCGCCGAC GAACTCGCCT GCGTCTTGCT GTTTTTGAAA


 


451
GAGTTTTTGG GCTAA






This corresponds to the amino acid sequence <SEQ ID 156; ORF 041>:










m041.pep




1
ISSPEHIGLQ GGSNGGLITA AAFVREPQSI GALVCEVPLT DMIRYPLLSA


 


51
GSSWTDEYGN PQKYEVCKRR LGELSPYHNL SDGIDYPPAL ITTSLSDDRV


 


101
HPAHALKFYA KLRETSAQSW LYSPDGGGHT GNGTQRESAD ELACVLLFLK


 


151
EFLG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 157>:










a041.seq




1
ATCAGTTCGC CCGAACACAT CGGCTTGCAG GGCGGCAGCA ACGGCGGACT


 


51
GATTACTGCC GCCGCCTTCG TGCGCGAACC GCAAAGCATA GGCGCGCTGG


 


101
TGTGCGAAGT GCCGCTGACC GACATGATCC GTTATCCGCT GCTCTCCGCC


 


151
GGTTCAAGCT GGACAGACGA ATACGGCAAT CCGCAAAAAT ACGAAGTCTG


 


201
CAAACGCCGG TTGGGCGAAT TGTCGCCGTA TCACAATCTT TCAGACGGCA


 


251
TCGATTATCC GCCCGCGCTC ATTACCACCA GCCTGTCCGA CGATCGCGTC


 


301
CATCCCGCCC ACGCGCTCAA GTTCTACGCC AAACTGCGCG AAACCTCGCC


 


351
GCAATCTTGG CTCTACTCGC CTGACGGCGG CGGCCATACC GGCAACGGCA


 


401
CGCAGCGCGA AGCCGCCGAC GAACTCGCCT GCGTGTTGCT GTTTTTGAAA


 


451
GAGTTTTTGG GCTAA






This corresponds to the amino acid sequence <SEQ ID 15R; ORF 041.a>:










a041.pep




1
ISSPEHIGLQ GGSNGGLITA AAFVREPQSI GALVCEVPLT DMIRYPLLSA


 


51
GSSWTDEYGN PQKYEVCKRR LGELSPYHNL SDGIDYPPAL ITTSLSDDRV


 


101
HPAHALKFYA KLRETSPQSW LYSPDGGGHT GNGTQREAAD ELACVLLFLK


 


151
EFLG*






m041/a041 98.7% identity over a 154 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 041 shows 96.8% identity over a 154 aa overlap with a predicted ORF (ORF 041.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 159>:










g041-1.seq




1
ATGAAATCCT ACCCCGACCC CTACCGCCAT TTTGAAAACC TCGATTCCGC


 


51
CGAAACGCAA AACTTCGCTG CTGAAGCGAA TGCCGAAACG CGCGCGCGTT


 


101
TTTTAAACAA CGACAAGGCG CGCGCACTTT CAGACGGCAT TTTGAATCAA


 


151
ATGCAGGACA CGCGGCAGAT TCCGTTTTGT CAGGAACACC GCGCGCGGAT


 


201
GTACCATTTC CATCAGAATG CGGAATATCC GAAGGGCGTG TACCGCATGT


 


251
GTACGGCGGC GACCTACCGT TCCGGCTATC CCGAGTGGAA AATCCTGTTT


 


301
TCGGTGGCGG ATTTCGATGA GTTGCTCGGC GACGATGTGT ATTTGGGCGG


 


351
CGTGTCGCAC TTGGTGGAGC AGCCCAACCG CGCGCTGCTG ACTTTGAACA


 


401
AATCGGGCGG CGATACGGCG TATACGCTGG AAGTGGATTT GGAAGCAGGG


 


451
GAATTGGTAG AGGGCGGTTT TCACTTTCCG GCAGGCAAAA ACCATGTGTC


 


501
GTGGCGCGAT GAAAACAGCG TGTGGGTGTG TCCGGCTTGG GACGAACGCC


 


551
AGTTGACCGA ATCGGGCTAT CCGCGCGAAG TGTGGCTGGT GGAACGCGGC


 


601
AAGAGTTTCG AGGAAAGCCT GCCGGCGTAC CAAATCGATA AAGGCGCGAT


 


651
GATGGTAAAC GCGTGGCGTT ACCTCGATCC GCAGGGTTCG CCGATTGATT


 


701
TGATTGAAGC GTCGGACGGT TTTTACACCA AGACGTATTT GCAGGTGTCG


 


751
TCCGAAGGCG GGGCGAAACC GTTGAACCTG CCTAATGATT GCGATGTGGT


 


801
CGGCTATCTG GCGGGACATC TTTTGCTGAC GCTGCGCAAG GACTGGCACC


 


851
GCGCGAACCA AAGCTATCCG AGTGGCGCGT TGGTGGCGGT GAAACTGAAT


 


901
CGGGGCGAAC TCGGGGCGGC GCAGCTTTTG TTTGCGCCCG ATGAAACGCA


 


951
GGCATTGGAA AGCGTGGAAA CGACCAAGCG TTTTGTGGTG GCAAGCCTGC


 


1001
TGGAGAATGT ACAAGGCCGT CTGAAAGCGT GGCGGTTTGC CGACAGCAAA


 


1051
TGGCAGGAAG CCGAGTTGCC GCACCTGCCC TCGGGCGCGT TGGAAATGAC


 


1101
CGACCAACCG TGGGGCGGCG ACGTGGTTTA TCTTGCCGCC AGCGATTTCA


 


1151
CCACGCCGCT GACGCTGTTT GCGCTGGATT TGAACGTGAT GGAACTGACC


 


1201
GTCATGCGCC TCCAGCCGCA GCAGTTTGTT TCAGACGGCA TCGAAGTGCG


 


1251
GCAGTTTTGG GCGGTGTCGT CCGACGGCGA ACGCATTCCT TATTTCCACG


 


1301
TCGGCAAAAA CGCCGCGCCC GACACGCCGA CCTTAGTCTA TGCTTACGGA


 


1351
GGTTTCGGCA TTCCTGAATT GCCGCATTAT CTGGGCAGCG TCGGCAAATA


 


1401
TTGGCTGGAA GAGGGCAATG CCTTTGTATT GGCAAACATC CGCGGCGGCG


 


1451
GAGAATTCGG CCCGCGCTGG CATCAGGCGG CGCAGGGAAT CAGCAAACAC


 


1501
AAAAGCGTTG ATGATTTGTT GGCAGTCGTG CGTGATTTGT CCGAACGCGG


 


1551
CATGAGTTCG CCCAAACACA TCGGCTTGCA GGGCGGCAGC AACGGCGGCC


 


1601
TGATTACCGC CGCCGCCTTC GTGCGCGAAC CGCAAAGCAT CGGTGCGCTG


 


1651
GTGTGCGAAG TACCGCTGAC CGATATGATC CGTTATCCGC TGCTGTCCGC


 


1701
CGGTTCAAGT TGGACGGACG AATACGGCAA TCCGCAGAAA TACGAAGCCT


 


1751
GCAAACGCCG GCTGGGCGAA TTGTCGCCGT ATCACAATCT TTCAGACGGC


 


1801
ATCGATTATC CGCCCGCACT CATTACCACC AGCCTCAGCG ACGACCGCGT


 


1851
CCATCCCGCC CACGCGCTCA AATTCTACGC CAAACTGCGC GAAACCTCGC


 


1901
CGCAATCTTG GCTCTACTCG CCTGACGGCG GCGGCCATAC CGGCAACGGC


 


1951
ACCCAACGCG AATCCGCCGA CAAACTCGCC TGCGTGTTGC TGTTTTTGAA


 


2001
AGAATTTTTG GGATAA






This corresponds to the amino acid sequence <SEQ ID 160; ORF 041-1.ng>:










g041-1.pep




1
MKSYPDPYRH FENLDSAETQ NFAAEANAET RARFLNNDKA RALSDGILNQ


 


51
MQDTRQIPFC QEHRARMYHF HQNAEYPKGV YRMCTAATYR SGYPEWKILF


 


101
SVADFDELLG DDVYLGGVSH LVEQPNRALL TLNKSGGDTA YTLEVDLEAG


 


151
ELVEGGFHFP AGKNHVSWRD ENSVWVCPAW DERQLTESGY PREVWLVERG


 


201
KSFEESLPAY QIDKGAMMVN AWRYLDPQGS PIDLIEASDG FYTKTYLQVS


 


251
SEGGAKPLNL PNDCDVVGYL AGHLLLTLRK DWHRANQSYP SGALVAVKLN


 


301
RGELGAAQLL FAPDETQALE SVETTKRFVV ASLLENVQGR LKAWRFADSK


 


351
WQEAELPHLP SGALEMTDQP WGGDVVYLAA SDFTTPLTLF ALDLNVMELT


 


401
VMRLQPQQFV SDGIEVRQFW AVSSDGERIP YFHVGKNAAP DTPTLVYAYG


 


451
GFGIPELPHY LGSVGKYWLE EGNAFVLANI RGGGEFGPRW HQAAQGISKH


 


501
KSVDDLLAVV RDLSERGMSS PKHIGLQGGS NGGLITAAAF VREPQSIGAL


 


551
VCEVPLTDMI RYPLLSAGSS WTDEYGNPQK YEACKRRLGE LSPYHNLSDG


 


601
IDYPPALITT SLSDDRVHPA HALKFYAKLR ETSPQSWLYS PDGGGHTGNG


 


651
TQRESADKLA CVLLFLKEFL G*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 161>:










m041-1.seq




1
ATGAAATCCT ACCCCGACCC CTACCGCCAT TTTGAAAACC TCGATTCCGC


 


51
CGAAACGCAA AACTTCGCTG CTGAAGCGAA TGCCGAAACG CGCGCGCGTT


 


101
TTTTAGAAAA CGACAAGGCG CGCGCGCTTT CAGACGGCAT TTTGGCGCAG


 


151
TTGCAGGACA CGCGGCAGAT TCCGTTTTGT CAGGAACACC GCGCGCGGAT


 


201
GTACCATTTC CATCAGGACG CGGAGTATCC GAAGGGCGTG TACCGCGTGT


 


251
GTACCGCGGC GACGTATCGT TCCGGCTATC CCGAGTGGAA AATCCTGTTT


 


301
TCGGTGGCGG ATTTCGACGA ATTGCTTGGC GACGATGTGT ATTTGGGCGG


 


351
CGTGTCGCAC TTGGTGGAAC AGCCCAACCG CGCGTTGTTA ACACTGAGCA


 


401
AATTGGGCAG CGATACGGCG TACACGCTGG AAGTGGATTT GGAAGCAGGG


 


451
GAGTTGGTCG AAGGCGGTTT TCACTTTCCG GCAGGCAAAA ACCATGTGTC


 


501
GTGGCGCGAT GAAAACAGCG TGTGGGTGTG TCCGGCTTGG AACGAACGCC


 


551
AGTTGACCCA ATCGGGCTAT CCGCGCGAAG TATGGCTGGT GGAACGCGGC


 


601
AAGAGTTTCG AGGAAAGCCT GCCTGTGTAT CAAATCGGCG AAGACGGCAT


 


651
GATGGTGAAC GCGTGGCGTT ATCTCGATCC GCAGGGTTCG CCGATTGATT


 


701
TGATTGAAGC GTCGGACGGT TTTTACACCA AAACCTATTT GCGGGTCTCA


 


751
GCCGAAGGCG AGGCGAAACC GTTAAACCTG CCCAACGATT GCGACGTGGT


 


801
CGGCTATCTG GCGGGGCATC TTTTGCTGAC GCTGCGCAAG GACTGGAACC


 


851
GCGCGAACCA AAGCTATCCG AGCGGCGCGC TGGTGGCGGT GAAGCTGAAT


 


901
CGGGGCGAAC TCGGGGCGGC GCAGCTTTTG TTTGCGCCCG ATGAAACGCA


 


951
GGCATTGGAA AGCGTGGAAA CGACCAAGCG TTTTGTGGTG GCGAGCCTGT


 


1001
TGGAGAACGT ACAAGGCCGT CTGAAAGCAT GGCGGTTTGC CGACGGCAAA


 


1051
TGGCAGGAAG TCGAATTGCC GCGCCTGCCT TCGGGCGCGT TGGAAATGAC


 


1101
CGACCAACCT TGGGGCGGCG ACGTGGTTTA CCTTGCCGCC AGCGATTTCA


 


1151
CCACGCCGCT GACGCTGTTT GCGCTGGATT TGAACGTGAT GGAACTGACC


 


1201
GTCATGCGCC GCCAGCCGCA GCAGTTTGAT TCAGACGGCA TTAACGTGCA


 


1251
GCAGTTTTGG ACGACTTCGG CTGACGGCGA GCGCATTCCT TATTTCCACG


 


1301
TCGGCAAAAA CGCCGCGCCC GACATGCCGA CGCTGGTCTA TGCCTACGGC


 


1351
GGTTTCGGCA TTCCCGAATT GCCGCATTAT CTGGGCAGCA TTGGCAAATA


 


1401
TTGGCTGGAA GAGGGCAATG CCTTTGTATT GGCGAACATC CGCGGCGGCG


 


1451
GCGAGTTCGG CCCGCGCTGG CATCAGGCGG CGCAGGGAAT CAGCAAACAT


 


1501
AAAAGCGTTG ATGATTTATT GGCAGTCGTG CGCGATTTGT CCGAACGCGG


 


1551
TATCAGTTCG CCCGAACACA TCGGCTTGCA GGGCGGCAGC AACGGCGGAC


 


1601
TGATTACTGC CGCCGCCTTC GTGCGCGAAC CGCAAAGCAT CGGCGCGCTG


 


1651
GTGTGCGAAG TGCCGCTGAC CGACATGATC CGTTATCCGC TGCTCTCCGC


 


1701
CGGTTCAAGC TGGACAGACG AATACGGCAA TCCGCAAAAA TACGAAGTCT


 


1751
GCAAACGCCG GTTGGGCGAA TTGTCGCCGT ATCACAATCT TTCAGACGGC


 


1801
ATCGATTATC CGCCCGCGCT CATTACCACC AGCCTGTCCG ACGATCGCGT


 


1851
CCATCCCGCC CACGCGCTCA AGTTCTACGC CAAACTGCGC GAAACCTCCG


 


1901
CGCAATCTTG GCTCTACTCG CCTGACGGCG GCGGCCATAC CGGCAACGGC


 


1951
ACCCAACGCG AATCCGCCGA CGAACTCGCC TGCGTCTTGC TGTTTTTGAA


 


2001
AGAGTTTTTG GGCTAA






This corresponds to the amino acid sequence <SEQ ID 162; ORF 041-1>:










m041-1.pep




1
MKSYPDPYRH FENLDSAETQ NFAAEANAET RARFLENDKA RALSDGILAQ


 


51
LQDTRQIPFC QEHRARMYHF HQDAEYPKGV YRVCTAATYR SGYPEWKILF


 


101
SVADFDELLG DDVYLGGVSH LVEQPNRALL TLSKLGSDTA YTLEVDLEAG


 


151
ELVEGGFHFP AGKNHVSWRD ENSVWVCPAW NERQLTQSGY PREVWLVERG


 


201
KSFEESLPVY QIGEDGMMVN AWRYLDPQGS PIDLIEASDG FYTKTYLRVS


 


251
AEGEAKPLNL PNDCDVVGYL AGHLLLTLRK DWNRANQSYP SGALVAVKLN


 


301
RGELGAAQLL FAPDETQALE SVETTKRFVV ASLLENVQGR LKAWRFADGK


 


351
WQEVELPRLP SGALEMTDQP WGGDVVYLAA SDFTTPLTLF ALDLNVMELT


 


401
VMRRQPQQFD SDGINVQQFW TTSADGERIP YFHVGKNAAP DMPTLVYAYG


 


451
GFGIPELPHY LGSIGKYWLE EGNAFVLANI RGGGEFGPRW HQAAQGISKH


 


501
KSVDDLLAVV RDLSERGISS PEHIGLQGGS NGGLITAAAF VREPQSIGAL


 


551
VCEVPLTDMI RYPLLSAGSS WTDEYGNPQK YEVCKRRLGE LSPYHNLSDG


 


601
IDYPPALITT SLSDDRVHPA HALKFYAKLR ETSAQSWLYS PDGGGHTGNG


 


651
TQRESADELA CVLLFLKEFL G*






m041-1/g041-1 94.6% identity in 671 aa overlap













sp|P55577|Y4NA_RHISN PROBABLE PEPTIDASE Y4NA >gi|2182536



(AE000086) Y4nA [Rhizobium sp. NGR234] Length = 726


Score = 370 bits (940), Expect = e−101


Identities = 217/682 (31%), Positives = 331/682 (47%), Gaps = 22/682 (3%)











Query:
2
KSYPDPYRHFENLDSAETQNFAAEANAETRARFLENDKARALSDGILAQLQDTRQIPFCQ
61





K   DP  +   +D  +   +    N  T  +  ++ +        L  LQ T +I


Sbjct:
42
KDASDPRAYLNEIDGDKAMTWVEAHNLSTVDKLSKDPRYSEYQADALTILQATDRIASPS
101


 


Query:
62
EHRARMY-HFHQDAEYPKGVYRVCTAATYRSGYPEWKILFSVADFDELLGDDVYLGGVSH
120




  R  M  +F QD  + +G++R  T  +YRSG P+W+ +  V    +  G      G


Sbjct:
102
FARDGMIDNFWQDGTHVQGLWRRTTWESYRSGNPQWRTILDVDALSKAEGKTWVFEGGDC
161


 


Query:
121
LVEQPNRALLTLSKLGSDTAYTLEVDLEAGELVEGGFHFPAGKNHVSWRDENSVWVCPAW
180




L    N  L+ LS  G D     E D+  GE V+ GF  P GK  V+W DEN+++V   W


Sbjct:
162
LPPTSNLCLIRLSDGGKDADVVREFDIAKGEFVKEGFVLPEGKQSVTWVDENTIYVTREW
221


 


Query:
181
NERQLTQSGYPREVWLVERGKSFEESLPVYQ------IGEDGMM--VNAWRYLDPQGSPI
232




   ++T SGY     +V+RG+S ++++ +++      E G++  ++    +D     +


Sbjct:
222
TPGEVTSSGYAYVTKVVKRGQSLDQAVEIFRGQKKDVSAERGVLRDIDGKYVMDTSYRGL
281


 


Query:
233
DLIEASDGFYTKTYLRVSAEGEAKPLNLPNDCDVVGYLAGHLLLTLRKDWNRANQS-YPS
291




D       FY   +     +     L LP      GY  G  +  L+ DW  A  + + +


Sbjct:
282
DFFNTELAFYPNGH----PDTRKVVLPLPTTAVFSGYYKGQAIYWLKSDWTSAKGTVFHN
337


 


Query:
292
GALVAVKLNRGELGAAQL----LFAPDETQALESVETTKRFVVASLLENVQGRLKAWRFA
347




GA++A  L       A++    LF P+E Q++     TK  +V S+L NV   ++++ F


Sbjct:
338
GAIIAFDLKAALADPARVEPLVLFMPNEHQSVAGTTQTKNRLVLSILSNVTSEVRSFDFG
397


 


Query:
348
DGKWQEVELPRLPSGALEMTDQPWGGDVVYLAASDFTTPLTLFALDLNVMELTVMRRQPQ
407




 G W   +L    +  L +T      D +++ +  F  P TLF  D    ++  +   P


Sbjct:
398
KGGWSSFKLALPENSTLSLTSSDDESDQLFVFSEGFLEPSTLFCADAATGQVEKITSTPA
457


 


Query:
408
QFDSDGINVQQFWTTSADGERIPYFHVGKNAAP---DMPTLVYAYGGFGIPELPHYLGSI
464




+FD+G+  QQFW TS DG ++PYF V +         PT++YAYGGF IP++P Y   +


Sbjct:
458
RFDAGGLQAQQFWATSKDGTKVPYFLVARKDVKLDGTNPTILYAYGGFQIPMQPSYSAVL
517


 


Query:
465
GKYWLEEGNAFVLANIRGGGEFGPRWHQAAQGISKHKSVDDLLAVVRDLSERGISSPEHI
524




GK WLE+G A+ LANIRGGGEFGP+WH A    ++ +  DD  AV +DL  + ++S  H+


Sbjct:
518
GKLWLEKGGAYALANIRGGGEFGPKWHDAGLKTNRQRVYDDFQAVAQDLIAKKVTSTPHL
577


 


Query:
525
GLQGGSNGGLITAAAFVREPQSIGALVCEVPLTDMIRYPLLSAGSSWTDEYGNPQKYEVC
584




G+ GGSNGGL+     ++ P    A+V +VPL DM+ +  +SAG+SW  EYG+P    V


Sbjct:
578
GIMGGSNGGLLMGVQMIQRPDLWNAVVIQVPLLDMVNFTRMSAGASWQAEYGSPDD-PVE
636


 


Query:
585
KRRLGELSPYHNLSDGIDYPPALITTSLSDDRVHPAHALKFYAKLRETSAQSWLYSPDGG
644




   L  +SPYHN+  G+ YP     TS  DDRV P HA K  A   +     + Y    G


Sbjct:
637
GAFLRSISPYHNVKAGVAYPEPFFETSTKDDRVGPVHARKMAALFEDMGLPFYYYENIEG
696


 


Query:
645
GHTGNGTQRESADELACVLLFL
666




GH      +E A   A   +++


Sbjct:
697
GHAAAANLQEHARRYALEYIYM
718






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 163>:










a041-1.seq




1
ATGAAATCCT ACCCCGACCC CTACCGCCAT TTTGAAAACC TCGATTCCGC


 


51
CGAAACGCAA AACTTCGCTG CTGAAGCGAA TGCCGAAACG CGCGCGCGTT


 


101
TTTTAAACAA CGACAAGGCA CGCGCATTGT CTGACGGCAT TTTGGCGCAG


 


151
TTGCAGGACA CGCGGCAAAT TCCGTTTTGT CAGGAACACC GCGCGCGGAT


 


201
GTACCATTTC CATCAAGATG CGGAATATCC GAAAGGCGTG TACCGCGTGT


 


251
GTACCGCGGC GACTTACCGT TCGGGCTATC CTGAGTGGAA AATCCTGTTT


 


301
TCGGTGGCGG ATTTCGACGA ATTGCTCGGT GACGATGTAT ATCTAGGCGG


 


351
CGTGTCGCAC CTGGTGGAAC AGCCCAACCG CGCGTTGTTA ACACTGAGCA


 


401
AATCGGGCGG CGATACCGCG TACACGCTGG AAGTGGATTT GGAAGCAGGG


 


451
GAGTTGGTAG AAGGCGGTTT TCACTTTCCG GCAGGCAAAA ACCATGTGTC


 


501
GTGGCGCGAT GAAAACAGCG TGTGGGTGTG TCCGGCTTGG GACGAACGCC


 


551
AGTTGACCGA ATCGGGCTAT CCGCGCGAGG TGTGGCTGGT GGAACGCGGC


 


601
AAGAGTTTCG AGGAAAGCCT GCCGGTGTAC CAAATTGCTG AAGACGGCAT


 


651
GATGGTGAAC GCGTGGCGTT ACCTCGATCC GCAGGGTTCG CCGATTGATT


 


701
TGATTGAAGC GTCTGACGGT TTTTACACCA AAACCTATTT GCAGGTCTCA


 


751
GCCGAAGGCG AAGCGAAACC GTTAAACCTG CCCAACGATT GCGACGTAGT


 


801
CGGCTATCTG GCCGGACATC TTTTGCTGAC CTTGCGTAAA GACTGGCACC


 


851
GCGCGAACCA AAGCTATCCG AGTGGCGCAT TGGTAGCAGT AAAATTAAAC


 


901
CGCGGCGAAT TGGGCGCGGC GCAGCTTTTG TTTGCGCCCA ATGAAACGCA


 


951
GGCATTGGAA AGCGTGGAAA CGACCAAGCG TTTTGTCGTG GCGAGCCTGC


 


1001
TGGAAAACGT ACAGGGTCGT CTGAAAGCGT GGCGTTTTAC TGATGGCAAA


 


1051
TGGCAGGAAA CCGAGTTGCC GCGCCTGCCT TCGGGCGCGT TGGAAATGAC


 


1101
CGACCAACCG TGGGGGGGCG ACGTAGTTTA CCTTGCCGCC AGCGATTTCA


 


1151
CCACGCCGCT GACGCTGTTT GCATTGGATT TGAACGTGAT GGAACTGACC


 


1201
GTCATGCGCC GCCAGCCGCA GCAGTTTGAT TCAGACGGCA TTAACGTGCA


 


1251
GCAGTTTTGG ACGACTTCGG CTGACGGCGA GCGCATTCCT TATTTCCACG


 


1301
TCGGCAAAAA CGCCGCGCCC GACATGCCGA CGCTGGTCTA TGCCTACGGC


 


1351
GGTTTCGGCA TTCCCGAATT GCCGCATTAT CTGGGCAGCA TTGGCAAATA


 


1401
TTGGCTGGAA GAGGGCAATG CCTTTGTATT GGCGAACATC CGCGGCGGCG


 


1451
GCGAGTTCGG CCCGCGCTGG CATCAGGCGG CGCAGGGAAT CAGCAAACAT


 


1501
AAAAGCGTTG ATGATTTATT GGCAGTCGTG AGCGATTTGT CCGAACGCGG


 


1551
TATCAGTTCG CCCGAACACA TCGGCTTGCA GGGCGGCAGC AACGGCGGAC


 


1601
TGATTACTGC CGCCGCCTTC GTGCGCGAAC CGCAAAGCAT AGGCGCGCTG


 


1651
GTGTGCGAAG TGCCGCTGAC CGACATGATC CGTTATCCGC TGCTCTCCGC


 


1701
CGGTTCAAGC TGGACAGACG AATACGGCAA TCCGCAAAAA TACGAAGTCT


 


1751
GCAAACGCCG GTTGGGCGAA TTGTCGCCGT ATCACAATCT TTCAGACGGC


 


1801
ATCGATTATC CGCGCGCGCT CATTACCACC AGCCTGTCCG ACGATCGCGT


 


1851
CCATCCCGCC CACGCGCTCA AGTTCTACGC CAAACTGCGC GAAACCTCGC


 


1901
CGCAATCTTG GCTCTACTCG CCTGACGGCG GCGGCCATAC CGGCAACGGC


 


1951
ACGCAGCGCG AAGCCGCCGA CGAACTCGCC TGCGTGTTGC TGTTTTTGAA


 


2001
AGAGTTTTTG GGCTAA






This corresponds to the amino acid sequence <SEQ ID 164; ORF 041-1.a>:










a041-1.pep




1
MKSYPDPYRH FENLDSAETQ NFAAEANAET RARFLNNDKA RALSDGILAQ


 


51
LQDTRQIPFC QEHRARMYHF HQDAEYPKGV YRVCTAATYR SGYPEWKILF


 


101
SVADFDELLG DDVYLGGVSH LVEQPNRALL TLSKSGGDTA YTLEVDLEAG


 


151
ELVEGGFHFP AGKNHVSWRD ENSVWVCPAW DERQLTESGY PREVWLVERG


 


201
KSFEESLPVY QIAEDGMMVN AWRYLDPQGS PIDLIEASDG FYTKTYLQVS


 


251
AEGEAKPLNL PNDCDVVGYL AGHLLLTLRK DWHRANQSYP SGALVAVKLN


 


301
RGELGAAQLL FAPNETQALE SVETTKRFVV ASLLENVQGR LKAWRFTDGK


 


351
WQETELPRLP SGALEMTDQP WGGDVVYLAA SDFTTPLTLF ALDLNVMELT


 


401
VMRRQPQQFD SDGINVQQFW TTSADGERIP YFHVGKNAAP DMPTLVYAYG


 


451
GFGIPELPHY LGSIGKYWLE EGNAFVLANI RGGGEFGPRW HQAAQGISKH


 


501
KSVDDLLAVV SDLSERGISS PEHIGLQGGS NGGLITAAAF VREPQSIGAL


 


551
VCEVPLTDMI RYPLLSAGSS WTDEYGNPQK YEVCKRRLGE LSPYHNLSDG


 


601
IDYPPALITT SLSDDRVHPA HALKFYAKLR ETSPQSWLYS PDGGGHTGNG


 


651
TQREAADELA CVLLFLKEFL G*






a041-1/m041-1 97.9% identity in 671 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 165>:










g042.seq




1
ATGACGATGA TTTGCTTGCG CTTCCAagcG TTCGTGCCGC ATACCAGCGC


 


51
GTTATCCAAC ACTTCCACGG CAGCCGGCCC TTCCTGCCCG ATGGCGGCGG


 


101
TGCGGTCGAT GATGAAAATC CAGCCGGGGT TTTTCTCTTT GATGTATTCG


 


151
AAGGAAACGG GCTGCCCGTG CCCTTCGTTG CGTAAAGATT CGTCCACGGG


 


201
CGGCAGGCCG ATGTCGCCGT GTATCCAACT TGCCAACCGC GATTGCGTGC


 


251
CGAAGGCGGA CACCTTGTTG CCTGTAACCG ACAGCACCAG CCCGCGTCCT


 


301
TTGCCTTTGG cggCTTCGCG CTTTTGGGCG AACAGCGCGT CAATCTGCGC


 


351
ATTCAATTCC GCCACGCGCG CTTCCTTACC GAAAATCCGC GACAGGGTCT


 


401
CCATCTGCTT CTCGCCGCTG GTGCGGATAT TGCCGTTGTC CACCGTCAAA


 


451
TCTATGgtgG TCGCGTTTTT CGCCAACTGT TCATACGCTT CCGCACCCGG


 


501
CCCGCCGGTA ATGACAAACT GCGGATTGTG GCGGTGCAGG GATTCGCAAT


 


551
CGGGCTCAAA CAGCGTCCCC ACCGTTGCCG CCTTGTCAAA TGCAGGCTGC


 


601
AAATAG






This corresponds to the amino acid sequence <SEQ ID 166; ORF 042.ng>:










g042.pep




1
MTMICLRFQA FVPHTSALSN TSTAAGPSCP MAAVRSMMKI QPGFFSLMYS


 


51
KETGCPCPSL RKDSSTGGRP MSPCIQLANR DCVPKADTLL PVTDSTSPRP


 


101
LPLAASRFWA NSASICAFNS ATRASLPKIR DRVSICFSPL VRILPLSTVK


 


151
SMVVAFFANC SYASAPGPPV MTNCGLWRCR DSQSGSNSVP TVAALSNAGC


 


201
K*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 167>:










m042.seq




1
ATGACGATGA TTTGCTTGCG CTTCCAAGCG TTCGTGCCGC GTACCAGCGC


 


51
GTTATCCAmT ACTTCGACAG CCGcCGGCCy TTCyTGCCCG ATGGCGGCGG


 


101
TACGGTCGAT GATGAAAATC CAATCGGGGT TTTTCTCTTT GATGTATTCG


 


151
AAGGAAACAG GCTGCCCGTG CCCCTCGTTG CGTAAAGATT CGTCTACAGG


 


201
CGGTAGGCCG ATGTCGCCGT GTATCCAACT TGCCAACCGC GACTGCGTGC


 


251
CGAAGGCGGA CACCTTGTTG CCCGTAACCG ACAGCACCAG CCCGCGTCCT


 


301
TTGCCTTTGG CGGCTTCGCG CGTTTGGGCG AACAGCGCGT CAATCTGCGC


 


351
CTTCAATTCC GCCGCGCGCG CTTCCTTGCC GAAAATCCGC GCCAAGGTCT


 


401
CCATCTGCTT TTCGCCGCTG GTGCGGATAT TGCCGTTGTC CACCGTCAGA


 


451
TCTATGGTGG TCGCGTTTTT CGCTAACTGT TCATACGCTT CCGCGCCCGG


 


501
CCCGCCGGTA ATGACAAGCT GAGGATTGTA GCGGTGCAGG GCTTCGTAAT


 


551
CGGGCTCGAA CAGCGTCCCC ACCGTTGCCG CCTTGTCAAA TGCAGGCTGC


 


601
AAATAA






This corresponds to the amino acid sequence <SEQ ID 168; ORF 042>:










m042.pep




1
MTMICLRFQA FVPRTSALSX TSTAAGXSCP MAAVRSMMKI QSGFFSLMYS


 


51
KETGCPCPSL RKDSSTGGRP MSPCIQLANR DCVPKADTLL PVTDSTSPRP


 


101
LPLAASRVWA NSASICAFNS AARASLPKIR AKVSICFSPL VRILPLSTVR


 


151
SMVVAFFANC SYASAPGPPV MTSXGLXRCR ASXSGSNSVP TVAALSNAGC


 


201
K*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 169>:










a042.seq




1
ATGACGATGA TTTGCTTGCG CTTCCAAGCG TTCGTGCCGC GTACCAGCGC


 


51
GTTATCCAAT ACTTCGACAG CCGCCGGCCC TTCCTGCCCG ATGGCGGCGG


 


101
TACGGTCGAT GATGAAAATC CAATCGGGGT TTTTCTCTTT GATGTATTCG


 


151
AAGGAAACAG GCTGCCCGTG CCCCTCGTTG CGTAAAGATT CGTCTACAGG


 


201
CGGTAGGCCG ATGTCGCCGT GTATCCAACT TGCCAACCGC GACTGCGTGC


 


251
CGAAGGCGGA CACCTTGTTG CCCGTAACCG ACAGCACCAG CCCGCGTCCT


 


301
TTGCCTTTGG CGGCTTCGCG CGTTTGGGCG AACAGCGCGT CAATCTGCGC


 


351
CTTCAATTCC GCCGCGCGCG CTTCCTTGCC GAAAATCCGC GCCAAGGTCT


 


401
CCATCTGCTT TTCGCCGCTG GTGCGGATAT TGCCGTTGTC CACCGTCAGA


 


451
TCTATGGTGG TCGCGTTTTT CGCCAACTGT TCATACGCTT CCGCGCCCGG


 


501
CCCGCCGGTA ATGACAAGCT GAGGATTGTA GCGGTGCAGG GCTTCGTAAT


 


551
CGGGCTCGAA CAGCGTCCCC ACCGTTGCCG CCTTGTCAAA TGCAGGCTGC


 


601
AAATAA






This corresponds to the amino acid sequence <SEQ ID 170; ORF 042.a>:










a042.pep




1
MTMICLRFQA FVPRTSALSN TSTAAGPSCP MAAVRSMMKI QSGFFSLMYS


 


51
KETGCPCPSL RKDSSTGGRP MSPCIQLANR DCVPKADTLL PVTDSTSPRP


 


101
LPLAASRVWA NSASICAFNS AARASLPKIR AKVSICFSPL VRILPLSTVR


 


151
SMVVAFFANC SYASAPGPPV MTS*GL*RCR AS*SGSNSVP TVAALSNAGC


 


201
K*






m042/a042 99.0% identity over a 201 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 042 shows 93.0% identity over a 201 aa overlap with a predicted ORF (ORF 042.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 171>:










m042-1.seq




1
ATGACGATGA TTTGCTTGCG CTTCCAAGCG TTCGTGCCGC GTACCAGCGC


 


51
GTTATCCAAT ACTTCGACAG CCGCCGGCCC TTCCTGCCCG ATGGCGGCGG


 


101
TACGGTCGAT GATGAAAATC CAATCGGGGT TTTTCTCTTT GATGTATTCG


 


151
AAGGAAACAG GCTGCCCGTG CCCCTCGTTG CGTAAAGATT CGTCTACAGG


 


201
CGGTAGGCCG ATGTCGCCGT GTATCCAACT TGCCAACCGC GACTGCGTGC


 


251
CGAAGGCGGA CACCTTGTTG CCCGTAACCG ACAGCACCAG CCCGCGTCCT


 


301
TTGCCTTTGG CGGCTTCGCG CGTTTGGGCG AACAGCGCGT CAATCTGCGC


 


351
CTTCAATTCC GCCGCGCGCG CTTCCTTGCC GAAAATCCGC GCCAAGGTCT


 


401
CCATCTGCTT TTCGCCGCTG GTGCGGATAT TGCCGTTGTC CACCGTCAGA


 


451
TCTATGGTGG TCGCGTTTTT CGCTAACTGT TCATACGCTT CCGCGCCCGG


 


501
CCCGCCGGTA A






This corresponds to the amino acid sequence <SEQ ID 172; ORF 042-1>:










m042-1.pep




1
MTMICLRFQA FVPRTSALSN TSTAAGPSCP MAAVRSMMKI QSGFFSLMYS


 


51
KETGCPCPSL RKDSSTGGRP MSPCIQLANR DCVPKADTLL PVTDSTSPRP


 


101
LPLAASRVWA NSASICAFNS AARASLPKIR AKVSICFSPL VRILPLSTVR


 


151
SMVVAFFANC SYASAPGPPV MTS*






m042-1/g042 95.4% identity in 173 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 173>:










a042-1.seq




1
ATGACGATGA TTTGCTTGCG CTTCCAAGCG TTCGTGCCGC GTACCAGCGC


 


51
GTTATCCAAT ACTTCGACAG CCGCCGGCCC TTCCTGCCCG ATGGCGGCGG


 


101
TACGGTCGAT GATGAAAATC CAATCGGGGT TTTTCTCTTT GATGTATTCG


 


151
AAGGAAACAG GCTGCCCGTG CCCCTCGTTG CGTAAAGATT CGTCTACAGG


 


201
CGGTAGGCCG ATGTCGCCGT GTATCCAACT TGCCAACCGC GACTGCGTGC


 


251
CGAAGGCGGA CACCTTGTTG CCCGTAACCG ACAGCACCAG CCCGCGTCCT


 


301
TTGCCTTTGG CGGCTTCGCG CGTTTGGGCG AACAGCGCGT CAATCTGCGC


 


351
CTTCAATTCC GCCGCGCGCG CTTCCTTGCC GAAAATCCGC GCCAAGGTCT


 


401
CCATCTGCTT TTCGCCGCTG GTGCGGATAT TGCCGTTGTC CACCGTCAGA


 


451
TCTATGGTGG TCGCGTTTTT CGCCAACTGT TCATACGCTT CCGCGCCCGG


 


501
CCCGCCGGTA A






This corresponds to the amino acid sequence <SEQ ID 174; ORF 042-1.a>:










a042-1.pep




1
MTMICLRFQA FVPRTSALSN TSTAAGPSCP MAAVRSMMKI QSGFFSLMYS


 


51
KETGCPCPSL RKDSSTGGRP MSPCIQLANR DCVPKADTLL PVTDSTSPRP


 


101
LPLAASRVWA NSASICAFNS AARASLPKIR AKVSICFSPL VRILPLSTVR


 


151
SMVVAFFANC SYASAPGPPV MTS*






m042-1/a042-1 100.0% identity in 173 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 175>:










g043.seq




1
ATGGTTGTTT CAAATCAAAA TATCTATGCC GTCGGCCCAT CAGCACTTTT


 


51
TCACATCCGA AGGCAAAAAT CCGTAATGCC GCCTGAACGC TTCgttgaAC


 


101
CGTCCCGCGT ggcggtagcc gcAAAAGTGC ATcGCGGCTT GGATGGTGCT


 


151
GCCCGATTCG ATGAGGGcga gcGCGTGTTC CAGCCGCAGG CGGCGCAGGC


 


201
GTCCGGCGAC GGTTTCGCCG GTTTGCGCTT TGAAATAGCG TTTCAGGTAG


 


251
CATTCGTTCA GCCCGACGCG GCGGGCGATT TCGGCGATGG TCAGCGGGCG


 


301
GGCGAATTCG CTGTTCAAAA TATCGGCGGC TTCGTCTATG CGCCGGCGGC


 


351
GGTAGCCGTT GTCGTGGCGG CGGAAGGTGA AGCGTAA






This corresponds to the amino acid sequence <SEQ ID 176; ORF 043.ng>:










g043.pep




1
MVVSNQNIYA VGPSALFHIR RQKSVMPPER FVEPSRVAVA AKVHRGLDGA


 


51
ARFDEGERVF QPQAAQASGD GFAGLRFEIA FQVAFVQPDA AGDFGDGQRA


 


101
GEFAVQNIGG FVYAPAAVAV VVAAEGEA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 177>:










m043.seq




1
ATGGTTGTTT CAAATCAAAA TATCTATGCC GCCGGCCCCT CAGCACTTCT


 


51
TCACATCCGA AGGCAAAAAT CCGTAATGCC GTCTGAACGC TTCGTTGAAC


 


101
CGTCCCGCGT GGCGGTAGCC GCAAAAGTGC ATGGCGGCTT GGACGGTGCT


 


151
GCCGGATTCG ATGAGGGCGA GCGCGTGTTC CAGCCGCAGG CGGCGCAgGC


 


201
ATCCGGCGAC GGTTTCGCCG GTTTGCGCTT TGAAATAGCG TTTCAGGTAG


 


251
CATTCGTTCA GTCCGACGCG GCGGGCGATT TCGGCGATGG TCAGCGGACG


 


301
GGCGAATTCG TGTTGCAGGA TGTCGGCGGC TTCGTCTATG CGCCGACGGC


 


351
GGTAACCGTT GTCGTGGCGG CGGAAGGTGA AGCGCAATAA






This corresponds to the amino acid sequence <SEQ ID 178; ORF 043>:










m043.pep




1
MVVSNQNIYA AGPSALLHIR RQKSVMPSER FVEPSRVAVA AKVHGGLDGA


 


51
AGFDEGERVF QPQAAQASGD GFAGLRFEIA FQVAFVQSDA AGDFGDGQRT


 


101
GEFVLQDVGG FVYAPTAVTV VVAAEGEAQ*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 043 shows 89.8% identity over a 128 aa overlap with a predicted ORF (ORF043.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 179>:










a043.seq




1
ATGGTTGTTT CAAATCAAAA TATCTATGCC GCCGGCCCCT CAGCACTTCT


 


51
TCACATCCGA AGGCAAAAAT CCGTAATGCC GTCTGAACGC TTCGTTGAAC


 


101
CGTCCCGCGT GGCGGTAGCC GCAAAAGTGC ATGGCGGCTT GGACGGTGCT


 


151
GCCGGATTCG ATGAGGGCGA GCGCGTGTTC CAGCCGCAGG CGGCGCAGGC


 


201
ATCCGGCGAC GGTTTCGCCG GTTTGCGCTT TGAAATAGCG TTTCAGGTAG


 


251
CATTCGTTCA GTCCGACGCG GCGGGCGATT TCGGCGATGG TCAGCGGACG


 


301
GGCGAATTCG TGTTGCAGGA TGTCGGCGGC TTCGTCTATG CGCCGACGGC


 


351
GGTAACCGTT GTCGTGGCGG CGGAAGGTGA AGCGCAATAA






This corresponds to the amino acid sequence <SEQ ID 180; ORF 043.a>:










a043.pep




1
MVVSNQNIYA AGPSALLHIR RQKSVMPSER FVEPSRVAVA AKVHGGLDGA


 


51
AGFDEGERVF QPQAAQASGD GFAGLRFEIA FQVAFVQSDA AGDFGDGQRT


 


101
GEFVLQDVGG FVYAPTAVTV VVAAEGEAQ*






m043/a043 100.0% identity in 129 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 181>:










g044.seq




1
ATGCTGCCCG ACCAGAGCGT CGAGTTCTTG CCACAAGTCG TCGTTTTTGA


 


51
CGGGCTGTTT GGCGGCGGTT TTCCAGCCGT TGCGCTTCCA ACCGTGTATC


 


101
CAGTTTTCCA TGCCGTTTTT GACGTATTGC GAGTCGGTGC AGATGATGAC


 


151
GGTGCAGCGG CGTTTGAGCG ATTTCAGCCC TTCGATAACG GCGGTCAGCT


 


201
CCATGCGGTT GTTGGTGGTT TGCGCTTCGC CGCCGAAAAG TTCTTTTTCG


 


251
CGGCTGCCGT AGCGCATTAA






This corresponds to the amino acid sequence <SEQ ID 182; ORF 044.ng>:










g044.pep




1
MLPDQSVEFL PQVVVFDGLF GGGFPAVALP TVYPVFHAVF DVLRVGADDD


 


51
GAAAFERFQP FDNGGQLHAV VGGLRFAAEK FFFAAAVAH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 183>:










m044.seq




1
ATGCCGTCCG ACTAGAGCGT CGAGTTCTTT CCAGAAGTCG TCGTTTTTGA


 


51
CGGGCTGTTT GGAGGCGGTT TTCCAGCCGT TGCGCTTCCA ACCGTGTATC


 


101
CAGTTTTCCA TGCCATTTTT GACGTATTGC GAGTCGGTGC AGATGATGAC


 


151
GGTGCAGCGG CGTTTGAGCG ATTTCAGTCC TTCGATGACG GCAGTCAGTT


 


201
CCATGCGGTT GTTGGTGGTT TGCGCTTCGC CGCCGAAAAG TTCTTTTTCG


 


251
TGGCTACCGT AGCGCAyTAa






This corresponds to the amino acid sequence <SEQ ID 184; ORF 044>:










m044.pep




1
MPSDXSVEFF PEVVVFDGLF GGGFPAVALP TVYPVFHAIF DVLRVGADDD


 


51
GAAAFERFQS FDDGSQFHAV VGGLRFAAEK FFFVATVAH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 185>:










a044.seq




1
GTGCCGTCCG ACCAGCGCGT CGAGTTCTTT CCACAAGTCG TCGTTTTTGA


 


51
CGGGCTGTTT GGCGGCGGTT TTCCAGCCGT TGCGCTTCCA ACCGTGTATC


 


101
CAGTTTTCCA TGCCGTTTTT GACGTATTGC GAGTCGGTGC AGATGATGAC


 


151
GGTGCAGCGG CGTTTGAGCG ATTTCAGTCC TTCGATGACG GCGGTCAGTT


 


201
CCATACGGTT GTTGGTGGTT TGCGCTTCGC CGCCGAAAAG TTCTTTTTCG


 


251
TGGCTGCCGT AGCGCATTAA






This corresponds to the amino acid sequence <SEQ ID 186; ORF 044.a>:










a044.pep




1
VPSDQRVEFF PQVVVFDGLF GGGFPAVALP TVYPVFHAVF DVLRVGADDD


 


51
GAAAFERFQS FDDGGQFHTV VGGLRFAAEK FFFVAAVAH*






m044/a044 91.0% identity over a 89 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 044 shows 86.5% identity over a 89 aa overlap with a predicted ORF (ORF 044.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 187>:










g046.seq




1
ATGTCGGCAA TGCTGCGTCC GACAAGCAGC CCGCCGCgcc gCGCCTGTAT


 


51
GATGACCATC CGCACGCGGT CGTCTGCAAA ACGTAAAACC TGCAATGCGC


 


101
CCGGGCAGTC TATCAGGCCG GCAAGCTGTT CGGTAACGAG CTGTTCGGGG


 


151
CTGATGGTTT CGGTTATGCC gaATATGGAA AGGCTGCCGt TTTcGTTGTT


 


201
TTCGAGCTTG GGGCTGAGGT ATTCGAGGTA TtcgctGGAA CGGACGCGCG


 


251
CGATGCGGCC GGGGATGTTG AACAGGTCGG CGGCAACTTT GCAGGCGACG


 


301
ATGTTGGTTT CGTCGCTGCG GGagaGCGCG AGcagcaagt cggcatcttC


 


351
CgcgccggcG Cgttataatg tgAAGGGGGA TGCGccgttg ccgaAAACGG


 


401
TTTGGacatc gaggcggctg CCTGTTTCCT GCAATGCTTT TTCGTCGATG


 


451
TCGATAAcgg TTACGTCGTT GTTGGTGATG GCGGCAAGGT TTTGCGCGAC


 


501
GGTAGAACCT ACCTGCCCGT TGCCTAAAAT GAGGATTTTC ACGGTATGGG


 


551
TCGCCGGGTG A






This corresponds to the amino acid sequence <SEQ ID 1 RR; ORF 046.ng>:










g046.pep




1
MSAMLRPTSS PPRRACMMTI RTRSSAKRKT CNAPGQSIRP ASCSVTSCSG


 


51
LMVSVMPNME RLPFSLFSSL GLRYSRYSLE RTRAMRPGML NRSAATLQAT


 


101
MLVSSLRESA SSKSASSAPA RYNVKGDAPL PKTVWTSRRL PVSCNAFSSM


 


151
SITVTSLLVM AARFCATVEP TCPLPKMRIF TVWVAG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 189>:










m046.seq




1
ATGTCGGCAA TGCTGCGTCC GACAAGCAsT CCGC.r.sGC gCGcCTGTAT


 


51
GATGACCATC CGCACGCGGT CGTCTGCAAA ACGTAAAACC TGCAATGCGC


 


101
CCGGGCAGTC TATCAGGCCG GCAAGCTGTT CGGTAACGAG CTGTTCGGGG


 


151
CTGATGGTTT CGGTTATGCC GAATATGGAA AGGCTGCCGT TTTCGTTGTT


 


201
TTCGAGCTTG GGGCTGAGGT ATTCGAGGTA TTCGCTGGAA CGGACGCGCG


 


251
CGATGCGGCC GGGGATGTTG AACAGGTCGG CGGCAACTTT GCAGGCGACG


 


301
ATGTTGGTTT CGTCGCTGCG GGAGAGCGCG AGCAGCAAGT CGGCATCTTC


 


351
CGCGCCGGCG CGTTCTAATG TGAAGGGGGA TGCGCCGTTG CCGAAAACGG


 


401
TTTGGACATC GAGGCGGCTG CCTGTTTCCT GCAATGCTTT TTCGTCGATG


 


451
TCGATAACGG TTACGTCGTT GTTGGGTATG GCGGCAAGGT TTTGTGCGAC


 


501
GGTAGAACCT ACCTGTCCGT TGCCTAAAAT GAGGATTTTC ACGGTGTGGG


 


551
TCGCCGAGTG A






This corresponds to the amino acid sequence <SEQ ID 190; ORF 046>:










m046.pep




1
MSAMLRPTSX PXXRACMMTI RTRSSAKRKT CNAPGQSIRP ASCSVTSCSG


 


51
LMVSVMPNME RLPFSLFSSL GLRYSRYSLE RTRAMRPGML NRSAATLQAT


 


101
MLVSSLRESA SSKSASSAPA RSNVKGDAPL PKTVWTSRRL PVSCNAFSSM


 


151
SITVTSLLGM AARFCATVEP TCPLPKMRIF TVWVAE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 191>:










a046.seq




1
ATGTCGGCAA TGCTGCGTCC GACAAGCAGT CCGCCGCGCC GCGCCTGTAT


 


51
GATGACCATC CGCACGCGGT CGTCTGCAAA ACGTAAAACC TGCAATGCGC


 


101
CCGGGCAGTC TATCAGGCCG GCAAGCTGTT CGGTAACGAG CTGTTCGGGG


 


151
CTGATGGTTT CGGTTATGCC GAATATGGAA AGGCTGCCGT TTTCGTTGTT


 


201
TTCGAGCTTG GGGCTGAGGT ATTCGAGGTA TTCGCTGGAA CGGACGCGCG


 


251
CGATGCGGCC GGGGATGTTG AACAGGTCGG CGGCAACTTT GCAGGCGACG


 


301
ATGTTGGTTT CGTCGCTGCG GGAGAGCGCG AGCAGCAAGT CGGCATCTTC


 


351
CGCGCCGGCG CGTTCTAATG TGAAGGGGGA TGCGCCGTTG CCGAAAACGG


 


401
TTTGGACATC GAGGCGGCTG CCTGTTTCCT GCAATGCTTT TTCGTCGATG


 


451
TCGATAACGG TTACGTCGTT GTTGGGTATG GCGGCAAGGT TTTGTGCGAC


 


501
GGTAGAACCT ACCTGTCCGT TGCCTAAAAT GAGGATTTTC ACGGTGTGGG


 


551
TCGCCGAGTG A






This corresponds to the amino acid sequence <SEQ ID 192; ORF 046.a>:










a046.pep




1
MSAMLRPTSS PPRRACMMTI RTRSSAKRKT CNAPGQSIRP ASCSVTSCSG


 


51
LMVSVMPNME RLPFSLFSSL GLRYSRYSLE RTRAMRPGML NRSAATLQAT


 


101
MLVSSLRESA SSKSASSAPA RSNVKGDAPL PKTVWTSRRL PVSCNAFSSM


 


151
SITVTSLLGM AARFCATVEP TCPLPKMRIF TVWVAE*






m046/a046 98.4% identity over a 186 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 046 shows 97.3% identity over a 185 aa overlap with a predicted ORF (ORF 046.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 193>:










g047.seq




1
ATGGTCATCA TACAGGCGcg gcGCGGCGGG CTGCTTGTCG GACGCAGCAT


 


51
TGCCGACATC GCCCAAGATT TGCCCGACGG GGCCGACTGC CAAATCTGCG


 


101
CCGTTTACCG CAACAACCGC CTCATCGTCC CCGCGCCGCA AACCGTCATC


 


151
ATCGAAGGCG ACGAAATCCT GTTTGCCGCC GCCGCCGAAA ACATCGGGGC


 


201
GGTCATACCc gaATTGCGCC CCAAAGAAAC CAGCACCCGC CGCATCATGA


 


251
TTGCCGGCGG CGGCAACATc tgctACCGCC TCGCCAAGCA GCTCGAACAC


 


301
GCATAcaacG TCAAAATCAT CGAATGCCGG CCGCGCcgtg ccgaATGGAT


 


351
AGCCGAAAAC ctcgAcaaCA CCCTCGTCCT GCAAGGTTCG Gcaaccgacg


 


401
aAaccctgct cgAcaacgaa tacatcgacg aaatcgaCGT ATTCTGCGCC


 


451
CTGACCAACG ACGACGAAAG CAACATTAtg tCCGCCCTTT TGGCGAAAAA


 


501
CCTcggcgCG AAGCgcgtca tcggCATCGT CAACCGCTCA AGCTACGTCG


 


551
ATTTGCTCGA AGGCAACAAA ATCGACATCG TCGTCTCCCC CCACCTCATC


 


601
ACCATCGGCT CGATACTCGC CCACATCCGG CGCGGCGACA TCGTTGCCGT


 


651
CCACCCCATC CGGCGCGGCA CGGCGGAAGC CATCGAAGTC GTCGCGCACG


 


701
GCGACAAAAA AACTTCCGCC ATCATCGGCA GGCGCATCAG CGGCATCAAA


 


751
TGGCCCGAAG GCTGCCACAT TGCCGCCGTC GTCCGCGCCG GAACCGGCGA


 


801
AACCATTATG GGACACCATA CCGAAACCGT CATCCAAGAC GGTGACCACA


 


851
TCATCTTTTT CGTCTCGCGC CGGCGCATCC TGAACGAACT GGAGAAACTC


 


901
ATCCAAGTCA AAATGGGCTT TTTCGGATAA






This corresponds to the amino acid sequence <SEQ ID 194; ORF 047.ng>:










g047.pep




1
MVIIQARRGG LLVGRSIADI AQDLPDGADC QICAVYRNNR LIVPAPQTVI


 


51
IEGDEILFAA AAENIGAVIP ELRPKETSTR RIMIAGGGNI CYRLAKQLEH


 


101
AYNVKIIECR PRRAEWIAEN LDNTLVLQGS ATDETLLDNE YIDEIDVFCA


 


151
LTNDDESNIM SALLAKNLGA KRVIGIVNRS SYVDLLEGNK IDIVVSPHLI


 


201
TIGSILAHIR RGDIVAVHPI RRGTAEAIEV VAHGDKKTSA IIGRRISGIK


 


251
WPEGCHIAAV VRAGTGETIM GHHTETVIQD GDHIIFFVSR RRILNELEKL


 


301
IQVKMGFFG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 195>:










m047.seq




1
ATGGTCATCA TACAGgCGcG C..syGCGGA sTGCTTGTCG GACGCAGCAT


 


51
TGCCGACATC GCCCAAGATT TGCCCGACGG GGCCGACTGC CAAATCTGCG


 


101
CCGTTTACCG CAACAACCGC CTCATCGTCC CCGCGCCGCA AACCGTCATC


 


151
ATCGAAGGCG ACGAAATCCT ATTTGCCGCC GCCGCCGAAA ACATCGGCGC


 


201
GGTCATACCC GAATTGCGCC CCAAAGAAAC CCAAAGAAAC CAGCcCmgmm


 


251
GcATCATGAT TkCCGGCGGC GGCAACATCG GCTACCGTCT CGCCAAGCAG


 


301
CTCGAACACG CATACAACGT yAAAATCATC GAATGCCGGC CGCGCCGTGC


 


351
CGAATGGATA GCCGAAAACC TCGACAACAC CCTCGTCyTG CAAGGTTCGG


 


401
CAACCGACGA AACCCTGCTC GACAACGAAT ACATCGACGA AATCGACGTA


 


451
TTCTGCGCCC TGACCAACGA CGACGAAAGC AACATTATGT CCGCCCTTTT


 


501
GGCGAaAAAC CTCGGCGCGA AGCGCGTCAT CGGCATCGTC AACCGCTCAA


 


551
GCTACGTCGA TTTGCTCGAA GGCAACAAAA TCGACATCGT CGTCTCCCCC


 


601
CACCTCATCA CCATCGGCTC GATACTCGCC CACATCCGGC GCGGCGACAT


 


651
CGTTGCCGTC CACCCCATCC GGCGCGGCAC GGCGGAAGCC ATCGAAGTCG


 


701
TCGCACACGG CGACAAAAAA ACTTCCGCCA TCATCGGCAG GCGCATCAGC


 


751
GGCATCAAAT GGCCCGAAGG CTGCCACATT GCCGCCGTCG TCCGCGCCGG


 


801
AACCGGCGAA ACCATTATGG GACACCATAC CGAAACCGTC ATCCAAGACG


 


851
GCGACCACAT CATCTTTTTC GTCTCGCGCC GGCGCATCCT GAACGAACTG


 


901
GAAAAACTCA TCCAGGTCAA AATGGGCTTT TTCGGATAA






This corresponds to the amino acid sequence <SEQ ID 196; ORF 047>:










m047.pep




1
MVIIQARXXG XLVGRSIADI AQDLPDGADC QICAVYRNNR LIVPAPQTVI


 


51
IEGDEILFAA AAENIGAVIP ELRPKETQRN QPXXIMIXGG GNIGYRLAKQ


 


101
LEHAYNVKII ECRPRRAEWI AENLDNTLVL QGSATDETLL DNEYIDEIDV


 


151
FCALTNDDES NIMSALLAKN LGAKRVIGIV NRSSYVDLLE GNKIDIVVSP


 


201
HLITIGSILA HIRRGDIVAV HPIRRGTAEA IEVVAHGDKK TSAIIGRRIS


 


251
GIKWPEGCHI AAVVRAGTGE TIMGHHTETV IQDGDHIIFF VSRRRILNEL


 


301
EKLIQVKMGF FG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 197>:










a047.seq




1
ATGGTCATCA TACAGGCGCG GCGCGGCGGA CTGCTTGTCG GACGCAGCAT


 


51
TGCCGACATC GCCCAAGATT TGCCCGACGG GGCCGACTGC CAAATCTGCG


 


101
CCGTTTACCG CAACAACCGC CTCATCGTCC CCGCGCCGCA AACCGTCATC


 


151
ATCGAAGGCG ACGAAATCCT ATTTGCCGCC GCCGCCGAAA ACATCGGCGC


 


201
GGTCATACCC GAATTGCGCC CCAAAGAAAC CAGCACCCGC CGCATCATGA


 


251
TTGCCGGCGG CGGCAACATC GGCTACCGTC TCGCCAAGCA GCTCGAACAC


 


301
GCATACAACG TCAAAATCAT CGAATGCCGG CCGCGCCGTG CCGAATGGAT


 


351
AGCCGAAAAC CTCGACAACA CCCTCGTCCT GCAAGGTTCG GCAACCGACG


 


401
AAACCCTGCT CGACAACGAA TACATCGACG AAATCGACGT ATTCTGCGCC


 


451
CTGACCAACG ACGACGAAAG CAACATTATG TCCGCCCTTT TGGCGAAAAA


 


501
CCTCGGCGCG AAGCGCGTCA TCGGCATCGT CAACCGCTCA AGCTACGTCG


 


551
ATTTGCTCGA AGGCAACAAA ATCGACATCG TCGTCTCCCC CCACCTCATC


 


601
ACCATCGGCT CGATACTCGC CCACATCCGG CGCGGCGACA TCGTTGCCGT


 


651
CCACCCCATC CGGCGCGGCA CGGCGGAAGC CATCGAAGTC GTCGCACACG


 


701
GCGACAAAAA AACTTCCGCC ATCATCGGCA GGCGCATCAG CGGCATCAAA


 


751
TGGCCCGAAG GCTGCCACAT TGCCGCCGTC GTCCGCGCCG GAACCGGCGA


 


801
AACCATTATG GGACACCATA CCGAAACCGT CATCCAAGAC GGCGACCACA


 


851
TCATCTTTTT CGTCTCGCGC CGGCGCATCC TGAACGAACT GGAAAAACTC


 


901
ATCCAAGTCA AAATGGGCTT TTTCGGATAA






This corresponds to the amino acid sequence <SEQ ID 198; ORF 047.a>:










a047.pep




1
MVIIQARRGG LLVGRSIADI AQDLPDGADC QICAVYRNNR LIVPAPQTVI


 


51
IEGDEILFAA AAENIGAVIP ELRPKETSTR RIMIAGGGNI GYRLAKQLEH


 


101
AYNVKIIECR PRRAEWIAEN LDNTLVLQGS ATDETLLDNE YIDEIDVFCA


 


151
LTNDDESNIM SALLAKNLGA KRVIGIVNRS SYVDLLEGNK IDIVVSPHLI


 


201
TIGSILAHIR RGDIVAVHPI RRGTAEAIEV VAHGDKKTSA IIGRRISGIK


 


251
WPEGCHIAAV VRAGTGETIM GHHTETVIQD GDHIIFFVSR RRILNELEKL


 


301
IQVKMGFFG*






m047/a047 96.5% identity over a 312 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 047 shows 96.2% identity over a 312 aa overlap with a predicted ORF (ORF 047.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 199>:










g048.seq




1
ATGCTCGACA AAGGCGAGGA GTTGCCCGTC GATTTCACCA ACCGCCTGAT


 


51
TTACTACGTc ggcCCcgTCG ATCCGGTCGG CGATGAAGTC GTCGGTCCCG


 


101
CAGGTCCGAC CACAGCCACC CGCATGGACA AATTTACCCG CCAAATGCTC


 


151
AAACAAACCG GCCTCTTGGG CATGATCGGC AAATCCGagc gcgGcgcggc


 


201
cacctGCGAA GCcatCGCCG ACAACAAGGC CGTGTACCTC ATGGCAGTCG


 


251
GCGGCGCGGC ATACCTCGTG GCAAAAGCCA TCAAATCTTC CAAAGTCTTG


 


301
GCGTTCCCCG AATTGGGTAT GGAAGCCGTT TACGAATTTG AAGTCAAAGA


 


351
TATGCCCGTA ACCGTCGCCG TGGACAGCAA AGGCGAATCC ATCCACGCCA


 


401
CCGCCCCGCG CAAATGGCAG GCGAAAATCG GCATCATCCC CGTCGAGTCT


 


451
TGA






This corresponds to the amino acid sequence <SEQ ID 200; ORF 048.ng>:










g048.pep




1
MLDKGEELPV DFTNRLIYYV GPVDPVGDEV VGPAGPTTAT RMDKFTRQML


 


51
KQTGLLGMIG KSERGAATCE AIADNKAVYL MAVGGAAYLV AKAIKSSKVL


 


101
AFPELGMEAV YEFEVKDMPV TVAVDSKGES IHATAPRKWQ AKIGIIPVES


 


151
*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 201>:










m048.seq




1
ATGCTCAACA AAGGCGAAGA ATTGCCCGTC GATTTCACCA ACCGCCTGAT


 


51
TTACTACGTC GGCCCCGTCG ATCCGGTCGG CGATGAAGTC GTCGGTCCGG


 


101
CAGGTCCGAC CACAGCCACC CGCATGGACA AATTCACCCG CCAAATGCTC


 


151
GAACAAACCG ACCTCTTGGG CATGATCGGC AAATCCGAGC GCGGCGTGGC


 


201
CACCTGCGAA GCCATCGCCG ACAACAAAGC CGTGTACCTC ATGGCAGTCG


 


251
GCGGCGCGGC GTATCTCGTG GCAAAAGCCA TCAAATCTTC CAAAGTCTTG


 


301
GCGTTCCCCG AATTGGGCAT GGAAGCCATT TACGAATTTG AAGTCAAAGA


 


351
CATGCCCGTA ACCGTCGCCG TAGATAGCAA AGGCGAATCC ATCCACGCCA


 


401
CCGCCCCGCG CAAATGGCAG GCGAAAATCG GCATCATCCC CGTCGAATCT


 


451
TGA






This corresponds to the amino acid sequence <SEQ ID 202; ORF 048>:










m048.pep




1
MLNKGEELPV DFTNRLIYYV GPVDPVGDEV VGPAGPTTAT RMDKFTRQML


 


51
EQTDLLGMIG KSERGVATCE AIADNKAVYL MAVGGAAYLV AKAIKSSKVL


 


101
AFPELGMEAI YEFEVKDMPV TVAVDSKGES IHATAPRKWQ AKIGIIPVES


 


151
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 203>:










a048.seq




1
ATGCTCGACA AAGGCGAAGA ATTGCCCGTC GATTTCACCA ACCGCCTGAT


 


51
TTACTACGTC GGCCCCGTCG ATCCGGTCGG CGACGAAATC GTCGGCCCAG


 


101
CAGGTCCGAC CACCGCCACC CGCATGGACA AATTCACCCG CCAAATGCTC


 


151
GAACAAACCG ACCTCTTGGG CATGATCGGC AAATCCGAGC GCGGCGCGGC


 


201
CACCTGCGAA GCCATCGCCG ACAACAAAGC CGTGTACCTC ATGGCAGTCG


 


251
GCGGCGCGGC GTATCTCGTG GCAAAAGCCA TCAAATCTTC CAAAGTCTTG


 


301
GCGTTCCCCG AATTGGGCAT GGAAGCCATT TACGAATTTG AAGTCAAAGA


 


351
CATGCCCGTA ACCGTCGCCG TAGACAGCAA AGGCGAATCC ATCCACGCCA


 


401
CCGCCCCGCC CCAATGGCAG GCGAAAATCG GCATCATCCC CGTCAAATCT


 


451
TGA






This corresponds to the amino acid sequence <SEQ ID 204; ORF 048.a>:










a048.pep




1
MLDKGEELPV DFTNRLIYYV GPVDPVGDEI VGPAGPTTAT RMDKFTRQML


 


51
EQTDLLGMIG KSERGAATCE AIADNKAVYL MAVGGAAYLV AKAIKSSKVL


 


101
AFPELGMEAI YEFEVKDMPV TVAVDSKGES IHATAPPQWQ AKIGIIPVKS


 


151
*






m048/a048 96.0% identity over a 150 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 048 shows 96.4% identity over a 150 aa overlap with a predicted ORF (ORF 048.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 205>:










g049.seq




1
ATGCGGGCGC AGGCGTTTGA TCAACCGTTC GGTCAGCTCC TGTTCGGACA


 


51
GGCAGAACAC TTCGCGCCGG TTGACGGCTT TCGGGTTCAG GATATTGATT


 


101
TGGACGGGCA TCAACGCCTC TTCCGCACCG CCTTCGCCGT TTTCCGCAAC


 


151
CCCGTCTGCC GCCGTACCGG ATTCTGCCGC ATCGGCGTTT TCCCCGCCCT


 


201
CAATCTGTGC GGTTTCAAAT TCGGCACTGT CTTTTTTGGC ATCGAACCGG


 


251
ATTCTCCGCC GCGATTCGAT GTGTTTTTCC GAAAccggca tTTGCAGGGA


 


301
AGCCTgcgcg TTGAGCCAGT TTTCCTGAAG GACGATCATC GGGTCGGTTT


 


351
CGACTTCCTC GCCGCAATCG GCAACGGCgc tGTTGTGTTC TTCCTGCCAT


 


401
TTCTTCAGAT ACGCCTTTAA






This corresponds to the amino acid sequence <SEQ ID 206; ORF 049.ng>:










g049.pep




1
MRAQAFDQPF GQLLFGQAEH FAPVDGFRVQ DIDLDGHQRL FRTAFAVFRN


 


51
PVCRRTGFCR IGVFPALNLC GFKFGTVFFG IEPDSPPRFD VFFRNRHLQG


 


101
SLRVEPVFLK DDHRVGFDFL AAIGNGAVVF FLPFLQIRL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 207>:









m049.seq (partial)










1
ATGCGGGCGC AGGCGTTTGA TCAGCCGTTC GGTCAGCTCC TGTTCGGACA



 


51
GGCAGAACAC TTCGCGCCGG TTGACGGCTT TCGGGTTCAG GATATTGATT


 


101
TGGACGGGCA TCAACGTTTC TTCCGCATCG TTTTCCCCGT TTTCCGAAAC


 


151
CGCCGGCTCA TTCGTGCCGG ATTCTGCCTC GTCGGCGTTT TCCCCGCTTT


 


201
CAATCTGTCC GGTTTCAAAT TCGACACTGT CTTTTTTGGT ATCAAACCGG


 


251
ATTCTCCGCC GCGATTCGAT GTGTTTTTCC GAAACCGACA TTTGCAGGGA


 


301
AGCCTGCGCG TTGAGCCAGT TTTCCTGAAG GACGATCATC GGGTCGGTTT


 


351
CGACTTCCTC GCCGCAATCG GCAACGGCGG CATTGTGTTC CTCCTGCCAT


 


401
TTTTTCAGAT ACGCCTT...






This corresponds to the amino acid sequence <SEQ ID 208; ORF 049>:









m049.pep (partial)










1
MRAQAFDQPF GQLLFGQAEH FAPVDGFRVQ DIDLDGHQRF FRIVFPVFRN



 


51
RRLIRAGFCL VGVFPAFNLS GFKFDTVFFG IKPDSPPRFD VFFRNRHLQG


 


101
SLRVEPVFLK DDHRVGFDFL AAIGNGGIVF LLPFFQIRL...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 209>:










a049.seq




1
ATGCGGGCGC AGGCGTTTGA TCAGCCGTTC GGTCAGCTCC TGTTCGGACA


 


51
GGCAGAACAC TTCGCGCCGG TTGACGGCTT TCGGGTTCAG AATATTGATT


 


101
TGGACGGGCA TCAACGCTTC TTCCGCACCG CCTTCGCCGT TTTCCGCAAC


 


151
CCCGTCTGCC GCCGTACCCG ATTCTGCCGC ATCGGCGTTT TCCCCGCCTT


 


201
CAATCTGTCC GGTTTCAAAT TCGGCACTGT CTTTTTTGGC ATCAAACCGG


 


251
ATTCTCCGCC GCGATTCGAT GTGTTTTTCC GAAACCGACA TTTGCAGGGA


 


301
AGCCTGCGCG TTGAGCCAGT TTTCCTGAAG GACGATCATC GGGTCGGTTT


 


351
CGACTTCCTC GCCGCAATCG GCAACGGCGG CATTGTGTTC CTCCTGCCAT


 


401
TTTTTCAGAT ACGCCTT






This corresponds to the amino acid sequence <SEQ ID 210; ORF 049.a>:










a049.pep




1
MRAQAFDQPF GQLLFGQAEH FAPVDGFRVQ NIDLDGHQRF FRTAFAVFRN


 


51
PVCRRTRFCR IGVFPAFNLS GFKFGTVFFG IKPDSPPRFD VFFRNRHLQG


 


101
SLRVEPVFLK DDHRVGFDFL AAIGNGGIVF LLPFFQIRL






m049/a049 90.6% identity over a 139 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 049 shows 86.3% identity over a 139 aa overlap with a predicted ORF (ORF 049.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 211>:










g050.seq




1
atgggcgCGG GCTGGTGTCC TCCCGGCATC TTGGGCATCG GCATCGGCGg


 


51
cacgcccGAA AAAGccgtgt TGATGGcaaA AGAATCCCTG ATGAGCCACA


 


101
TCGAcatCca aGaATTGCAG GAAAAAGCCG CGTccggggc ggaattgtcc


 


151
accaccgaAG ccCTGCGCCT cGAACTCTTT GAAAAGGTCA ACGCGCTGGG


 


201
CATCGGCGCG CAAGGCTTGG GCGGTCTGAC CACCGTGTTG GACGTGAAAA


 


251
TCCTCGATTA CCCGACCCAT GCCGCCTCCA AACCGATTGC CATGATTCCC


 


301
AACTGTGCcg ccacCCGcca cgtcgAATTT GAATTGgACG GCTCAGGtcc


 


351
TGTCGAactc acgccGCcgc gtgtCGAAGA CTGA






This corresponds to the amino acid sequence <SEQ ID 212; ORF 050.ng>:










g050.pep




1
MGAGWCPPGI LGIGIGGTPE KAVLMAKESL MSHIDIQELQ EKAASGAELS


 


51
TTEALRLELF EKVNALGIGA QGLGGLTTVL DVKILDYPTH AASKPIAMIP


 


101
NCAATRHVEF ELDGSGPVEL TPPRVED*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 213>:










m050.seq




1
ATGGGCGCGG GCTGGTGTCC TCCCGGCATC TTGGGTATCG GCATCGGCGG


 


51
C..agCCgAA AAAGCCGTGC TGATGGCAAA AGAGTCCCTG ATGAGCCACA


 


101
TCGACATTCA AGAATTGCAG GAAAAGGCCG CGTCCGGCGC GgAATTGTCC


 


151
ACCACCGAAG CCCTGCGCCT CGAACTCTTT GAAAAAGTCA ACGCGCTGGG


 


201
CATCGGCGCA CAAGGCTTGG GCGGACTGAC CACCGTGTTG GACGTGAAAA


 


251
TCCTCGATTA TCCGACCCAC GCCGCCTCCA AACCGATTGC CATGATTCCG


 


301
AACTGCGCCG CCACCCGCCA CGTCGAATTT GAATTGGACG GCTCAGGCCC


 


351
TGTCGAACTC ACGCCGCCGC GCGTCGAAGA TGGCCCGATT TGA






This corresponds to the amino acid sequence <SEQ ID 214; ORF 050>:










m050.pep




1
MGAGWCPPGI LGIGIGGXAE KAVLMAKESL MSHIDIQELQ EKAASGAELS


 


51
TTEALRLELF EKVNALGIGA QGLGGLTTVL DVKILDYPTH AASKPIAMIP


 


101
NCAATRHVEF ELDGSGPVEL TPPRVEDGPI *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 215>:










a050.seq




1
ATGGGCGCGG GCTGGTGTCC TCCCGGCATC TTGGGCATCG GCATCGGCGG


 


51
TACGCCCGAA AAAGCCGTGT TGATGGCGAA AGAATCCCTG ATGAGCCACA


 


101
TCGACATCCA AGAATTGCAG GAAAAAGCCG CGTCCGGCGC GGAATTGTCC


 


151
ACCACCGAAG CCCTGCGCCT CGAACTCTTT GAAAAAGTCA ACGCGCTAGG


 


201
CATCGGCGCG CAAGGCTTGG GCGGTCTGAC CACCGTGTTG GACGTGAAAA


 


251
TCCTCGATTA CCCGACCCAC GCCGCCTCCA AACCGATTGC CATGATTCCG


 


301
AACTGCGCCG CCACCCGCCA CGTCGAATTT GAATTGGACG GCTCAGGCCC


 


351
TGTCGAACTC ACGCCGCCGC GCGTCGAAGA CTGGCCC






This corresponds to the amino acid sequence <SEQ ID 216; ORF 050.a>:










a050.pep




1
MGAGWCPPGI LGIGIGGTPE KAVLMAKESL MSHIDIQELQ EKAASGAELS


 


51
TTEALRLELF EKVNALGIGA QGLGGLTTVL DVKILDYPTH AASKPIAMIP


 


101
NCAATRHVEF ELDGSGPVEL TPPRVEDWP






m050/a050 97.7% identity over a 129 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 050 shows 98.4% identity over a 127 aa overlap with a predicted ORF (ORF 050.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 217>:










g050-1.seq




1
ATGACCGTTA TCAAGCAAGA AGACTTTATT CAAAGTATCT GCGATGCCTT


 


51
CCAATTCATC AGCTACTACC ATCCAAAAGA CTACATCGAC GCGCTTTATA


 


101
AGGCGTGGCA GAAGGAAGAA AATCCCGCCG CCAAAGACGC GATGACGCAG


 


151
ATTTTGGTCA ACAGCCGTAT GTGTGCCGAA AACAACCGCC CCATCTGCCA


 


201
AGACACAGGT ATCGCAACCG TCTTCCTCAA AGTCGGTATG GATGTGCAAT


 


251
GGGATGCGGA CATGAGCGTG GAAAAGATGG TTAACGAAGG CGTACGCCGC


 


301
GCCTACACTT GGGAAGGCAA CACCCTGCGC GCTTCCGTCC TCGCCGATCC


 


351
GGCCGGCAAA CGCCAAAACA CCAAAGACAA CACCCCCGCC GTCATCCACA


 


401
TGAGCATCGT GCCGGGCGGT AAAGTCGAAG TAACCTGCGC GGCAAAAGGC


 


451
GGCGGCTCTG AAAACAAATC CAAACTCGCT ATGCTCAACC CTTCCGACAA


 


501
CATCGTCGAT TGGGTATTGA AAACCATCCC GACGATGGGC GCGGGCTGGT


 


551
GTCCTCCCGG CATCTTGGGC ATCGGCATCG GCGGCAcgcC CGAAAAAGCC


 


601
GTGTTGATGG cgaAAGAATC CCTGATGAGC CACATCGACA TCCAAGAATT


 


651
GCAGGAAAAA GCCGCGTCCG GCGCGGAATT GTCCACCACC GAAGCCCTGC


 


701
GCCTCGAACT CTTTGAAAAG GTCAACGCGC TGGGCATCGG CGCGCAAGGC


 


751
TTGGGCGGTC TGACCACCGT GTTGGACGTG AAAATCCTCG ATTACCCGAC


 


801
CCATGCCGCC TCCAAACCGA TTGCCATGAT TCCCAACTGT GCCGCCACCC


 


851
GCCACGTCGA ATTTGAATTG GACGGCTCAG GTCCTGTCGA ACTCACGCCG


 


901
CCGCGCGTCG AAGACTGACC CGATCTGACT TACAGCCCCG ACAACGGCAA


 


951
ACGCGTCGAT GTCGATAAGC TGACCAAAGA AGAAGTGGCA AGCTGGAAAA


 


1001
CCGGCGACGT ATTGCTGTTG AACGGCAAAA TCCTCACCGG CCGCGATGCC


 


1051
GCGCACAAAC GCCTCGTCAA TATGCTCGAC AAAGGCGAGG AGTTGCCCGT


 


1101
CGATTTCACC AACCGCCTGA TTTACTACGT CGGCCCCGTC GATCCGGTCG


 


1151
GCGATGAAGT CGTCGGTCCC GCAGGTCCGA CCACAGCCAC CCGCATGGAC


 


1201
AAATTTACCC GCCAAATGCT CAAACAAACC GGCCTCTTGG GCATGATCGG


 


1251
CAAATCCGAG CGCGGCGCGG CCACCTGCGA AGCCATCGCC GACAACAAGG


 


1301
CCGTGTACCT CATGGCAGTC GGCGGCGCGG CATACCTCGT GGCAAAAGCC


 


1351
ATCAAATCTT CCAAAGTCTT GGCGTTCCCC GAATTGGGTA TGGAAGCCGT


 


1401
TTACGAATTT GAAGTCAAAG ATATGCCCGT AACCGTCGCC GTGGACAGCA


 


1451
AAGGCGAATC CATCCACGCC ACCGCCCCGC GCAAATGGCA GGCGAAAATC


 


1501
GGCATCATCC CCGTCGAGTC TTGA






This corresponds to the amino acid sequence <SEQ ID 218; ORF 050-1.ng>:










g050-1.pep




1
MTVIKQEDFI QSICDAFQFI SYYHPKDYID ALYKAWQKEE NPAAKDAMTQ


 


51
ILVNSRMCAE NNRPICQDTG IATVFLKVGM DVQWDADMSV EKMVNEGVRR


 


101
AYTWEGNTLR ASVLADPAGK RQNTKDNTPA VIHMSIVPGG KVEVTCAAKG


 


151
GGSENKSKLA MLNPSDNIVD WVLKTIPTMG AGWCPPGILG IGIGGTPEKA


 


201
VLMAKESLMS HIDIQELQEK AASGAELSTT EALRLELFEK VNALGIGAQG


 


251
LGGLTTVLDV KILDYPTHAA SKPIAMIPNC AATRHVEFEL DGSGPVELTP


 


301
PRVED*PDLT YSPDNGKRVD VDKLTKEEVA SWKTGDVLLL NGKILTGRDA


 


351
AHKRLVNMLD KGEELPVDFT NRLIYYVGPV DPVGDEVVGP AGPTTATRMD


 


401
KFTRQMLKQT GLLGMIGKSE RGAATCEAIA DNKAVYLMAV GGAAYLVAKA


 


451
IKSSKVLAFP ELGMEAVYEF EVKDMPVTVA VDSKGESIHA TAPRKWQAKI


 


501
GIIPVES*






g050-1/p14407









sp|P144O7|FUMB_ECOLI FUMARATE HYDRATASE CLASS I, ANAEROBIC (FUMARASE)



>gi|2800631|pir||B44511 fumarate hydratase (EC 4.2.1.2) fumB, iron-


dependent - Escherichia coli >gi|146048 (M27058) anaerobic class I


fumarase (EC 4.2.1.2) [Escherichia coli] Length = 48


Score = 172 bits (432), Expect = 4e−42


Identities = 138/488 (28%), Positives = 216/488 (43%), Gaps = 22/488 (4%)











Query:
11
QSICDAFQFISYYHPKDYIDALYKAWQKEENPAAKDAMTQILVNSRMCAENNRPICQDTG
70





Q+  DA   +   H K     L+     E +   K    Q L NS + A+   P CQDTG


Sbjct:
53
QAFHDASFMLRPAHQKQVAAILHDPEASEND---KYVALQFLRNSEIAAKGVLPTCQDTG
109


 


Query:
71
IATVFLKVGMDVQWDADMSVEKMVNEGVRRAYTWEGNTLRASVLADPAGKRQNTKDNTPA
130




 A +  K G  V W      E+ +++GV   Y  E N   +   A    K  NT  N PA


Sbjct:
110
TAIIVGKKGQRV-WTGGGD-EETLSKGVYNTYI-EDNLRYSQNAALDMYKEVNTGTNLPA
166


 


Query:
131
VIHMSIVPGGKVEVTCAAKGGGSENKSKLAMLNPSDNIVDWVLKTIPTMGAGWCP
185




 I +  V G + +  C AKGGGS NK+ L     A+L P   + +++++ + T+G   CP


Sbjct:
167
QIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPG-KLKNFLVEKMRTLGTAACP
225


 


Query:
186
PXXXXXXXXXTPEKAVLMAKESLMSHIDIQELQEKAASGAELSTTEALRLELFEKVNXXX
245




P         T  +  L   +   +H    EL  +     +      L  EL E+


Sbjct:
226
PYHIAFVIGGTSAETNLKTVKLASAHY-YDELPTEGNEHGQAFRDVQLEQELLEEAQKLG
284


 


Query:
246
XXXXXXXXXTTVLDVKILDYPTHAASKPIAMIPNCAATRHVEFELDGSG----PVELTPP
301




             D++++  P H AS P+ M  +C+A R+++ +++  G     +E  P


Sbjct:
285
LGAQFGGKYFAH-DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPG
343


 


uery:
302
RVEDXPDLTYSPDNGKRVDVDKLTKE---EVASWKTGDVLLLNGKILTGRDAAHKRLVNM
358




+               +VD+++  KE   +++ +     L L G I+ GRD AH +L  +


Sbjct:
344
QYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKEL
403


 


Query:
359
LDKGEELPVDFTNRLIYYXXXXXXXXXXXXXXXXXTTATRMDKFTRQMLKQTGLLGMIGK
418




+ D G+ELP    +  IYY                 TTA RMD +   +    G + M+ K


Sbjct:
404
IDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAK
463


 


Query:
419
SERGAATCEAIADNKAVYLMAVGG-AAYLVAKAIKSSKVLAFPELGMEAVYEFEVKDMPV
477




  R     +A   +   YL ++GG AA L  ++IK  + +A+PELGMEA+++ EV+D P


Sbjct:
464
GNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPA
523


 


Query:
478
TVAVDSKG
485




 + VD KG


Sbjct:
524
FILVDDKG
531






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 219>:










m050-1.seq




1
ATGACCGTCA TCAAACAGGA AGACTTTATC CAAAGCATTT GCGATGCCTT


 


51
CCAATTCATC AGCTACTATC ATCCCAAAGA CTACATCGAC GCGCTTTATA


 


101
AGGCGTGGCA GAAGGAAGAA AATCCTGCCG CCAAAGACGC GATGACGCAG


 


151
ATTTTGGTCA ACAGCCGTAT GTGTGCGGAA AACAACCGCC CCATCTGCCA


 


201
AGACACAGGT ATCGCAACCG TCTTCCTCAA AGTCGGTATG AACGTCCAAT


 


251
GGGATGCGGA CATGAGCGTG GAAGAGATGG TTAACGAAGG CGTACGCCGC


 


301
GCCTACACTT GGGAAGGCAA TACGCTGCGC GCTTCCGTCC TCGCCGATCC


 


351
GGCCGGCAAA CGCCAAAACA CCAAAGACAA CACCCCCGCC GTCATCCATA


 


401
TGAGCATCGT GCCGGGCGGT AAAGTCGAAG TAACCTGCGC GGCAAAAGGC


 


451
GGCGGCTCTG AAAACAAATC CAAACTCGCC ATGCTCAATC CTTCCGACAA


 


501
CATCGTCGAT TGGGTATTGA AAACCATCCC GACCATGGGC GCGGGCTGGT


 


551
GTCCTCCCGG CATCTTGGGT ATCGGCATCG GCGGCACGCC CGAAAAAGCC


 


601
GTGCTGATGG CAAAAGAGTC CCTGATGAGC CACATCGACA TTCAAGAATT


 


651
GCAGGAAAAG GCCGCGTCCG GCGCGGAATT GTCCACCACC GAAGCCCTGC


 


701
GCCTCGAACT CTTTGAAAAA GTCAACGCGC TGGGCATCGG CGCACAAGGC


 


751
TTGGGCGGAC TGACCACCGT GTTGGACGTG AAAATCCTCG ATTATCCGAC


 


801
CCACGCCGCC TCCAAACCGA TTGCCATGAT TCCGAACTGC GCCGCCACCC


 


851
GCCACGTCGA ATTTGAATTG GACGGCTCAG GCCCTGTCGA ACTCACGCCG


 


901
CCGCGCGTCG AAGACTGGCC CGATTTGACT TACAGCCCCG ACAACGGCAA


 


951
ACGCGTCGAT GTCGACAAGC TGACCAAAGA AGAAGTGGCA AGCTGGAAAA


 


1001
CCGGCGACGT ATTGCTGTTG AACGGCAAAA TCCTCACCGG CCGCGATGCC


 


1051
GCACACAAAC GCCTCGTCGA TATGCTCAAC AAAGGCGAAG AATTGCCCGT


 


1101
CGATTTCACC AACCGCCTGA TTTACTACGT CGGCCCCGTC GATCCGGTCG


 


1151
GCGATGAAGT CGTCGGTCCG GCAGGTCCGA CCACAGCCAC CCGCATGGAC


 


1201
AAATTCACCC GCCAAATGCT CGAACAAACC GACCTCTTGG GCATGATCGG


 


1251
CAAATCCGAG CGCGGCGTGG CCACCTGCGA AGCCATCGCC GACAACAAAG


 


1301
CCGTGTACCT CATGGCAGTC GGCGGCGCGG CGTATCTCGT GGCAAAAGCC


 


1351
ATCAAATCTT CCAAAGTCTT GGCGTTCCCC GAATTGGGCA TGGAAGCCAT


 


1401
TTACGAATTT GAAGTCAAAG ACATGCCCGT AACCGTCGCC GTAGATAGCA


 


1451
AAGGCGAATC CATCCACGCC ACCGCCCCGC GCAAATGGCA GGCGAAAATC


 


1501
GGCATCATCC CCGTCGAATC TTGA






This corresponds to the amino acid sequence <SEQ ID 220; ORF 050-1>:










m050-1.pep




1
MTVIKQEDFI QSICDAFQFI SYYHPKDYID ALYKAWQKEE NPAAKDAMTQ


 


51
ILVNSRMCAE NNRPICQDTG IATVFLKVGM NVQWDADMSV EEMVNEGVRR


 


101
AYTWEGNTLR ASVLADPAGK RQNTKDNTPA VIHMSIVPGG KVEVTCAAKG


 


151
GGSENKSKLA MLNPSDNIVD WVLKTIPTMG AGWCPPGILG IGIGGTPEKA


 


201
VLMAKESLMS HIDIQELQEK AASGAELSTT EALRLELFEK VNALGIGAQG


 


251
LGGLTTVLDV KILDYPTHAA SKPIAMIPNC AATRHVEFEL DGSGPVELTP


 


301
PRVEDWPDLT YSPDNGKRVD VDKLTKEEVA SWKTGDVLLL NGKILTGRDA


 


351
AHKRLVDMLN KGEELPVDFT NRLIYYVGPV DPVGDEVVGP AGPTTATRMD


 


401
KFTRQMLEQT DLLGMIGKSE RGVATCEAIA DNKAVYLMAV GGAAYLVAKA


 


451
IKSSKVLAFP ELGMEAIYEF EVKDMPVTVA VDSKGESIHA TAPRKWQAKI


 


501
GIIPVES*






m050-1/g050-1 98.2% identity in 507 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 221>:










a050-1.seq




1
ATGACCGTCA TCAAACAGGA AGACTTTATC CAAAGCATTT GCGATGCCTT


 


51
CCAATTCATC AGCTACTACC ATCCCAAAGA CTACATCGAC GCGCTTTATA


 


101
AGGCGTGGCA GAAGGAAGAA AACCCCGCCG CCAAAGACGC GATGACGCAG


 


151
ATTTTGGTCA ACAGCCGCAT GTGTGCCGAA AACAACCGCC CCATCTGCCA


 


201
AGATACCGGT ATCGCGACCG TGTTTTTGAA AGTCGGTATG GATGTGCAAT


 


251
GGGATGCAGA CATGAGCGTC GAAGAGATGG TTAACGAAGG CGTGCGCCGC


 


301
GCCTACACTT GGGAAGGCAA TACGCTGCGC GCTTCCGTTC TCGCCGACCC


 


351
CGCCGGCAAA CGCCAAAATA CCAAAGACAA CACGCCCGCC GTCATCCATA


 


401
TGAGCATCGT GCCGGGCGAC AAAGTCGAAG TAACCTGCGC GGCAAAAGGC


 


451
GGCGGTTCTG AAAACAAATC CAAACTCGCC ATGCTCAACC CTTCCGACAA


 


501
CATCGTCGAT TGGGTATTGA AAACCATTCC GACCATGGGC GCGGGCTGGT


 


551
GTCCTCCCGG CATCTTGGGC ATCGGCATCG GCGGTACGCC CGAAAAAGCC


 


601
GTGTTGATGG CGAAAGAATC CCTGATGAGC CACATCGACA TCCAAGAATT


 


651
GCAGGAAAAA GCCGCGTCCG GCGCGGAATT GTCCACCACC GAAGCCCTGC


 


701
GCCTCGAACT CTTTGAAAAA GTCAACGCGC TAGGCATCGG CGCGCAAGGC


 


751
TTGGGCGGTC TGACCACCGT GTTGGACGTG AAAATCCTCG ATTACCCGAC


 


801
CCACGCCGCC TCCAAACCGA TTGCCATGAT TCCGAACTGC GCCGCCACCC


 


851
GCCACGTCGA ATTTGAATTG GACGGCTCAG GCCCTGTCGA ACTCACGCCG


 


901
CCGCGCGTCG AAGACTGGCC CGATTTGACT TACAGCCCCG ACAACGGCAA


 


951
ACGCGTCGAT GTCGACAAGC TGACCAAAGA AGAAGTGGCA AGCTGGAAAA


 


1001
CCGGCGACGT ATTGCTGTTG AACGGCAAAA TCCTCACCGG CCGCGATGCC


 


1051
GCACACAAAC GCCTCGTCGA TATGCTCGAC AAAGGCGAAG AATTGCCCGT


 


1101
CGATTTCACC AACCGCCTGA TTTACTACGT CGGCCCCGTC GATCCGGTCG


 


1151
GCGACGAAAT CGTCGGCCCA GCAGGTCCGA CCACCGCCAC CCGCATGGAC


 


1201
AAATTCACCC GCCAAATGCT CGAACAAACC GACCTCTTGG GCATGATCGG


 


1251
CAAATCCGAG CGCGGCGCGG CCACCTGCGA AGCCATCGCC GACAACAAAG


 


1301
CCGTGTACCT CATGGCAGTC GGCGGCGCGG CGTATCTCGT GGCAAAAGCC


 


1351
ATCAAATCTT CCAAAGTCTT GGCGTTCCCC GAATTGGGCA TGGAAGCCAT


 


1401
TTACGAATTT GAAGTCAAAG ACATGCCCGT AACCGTCGCC GTAGACAGCA


 


1451
AAGGCGAATC CATCCACGCC ACCGCCCCGC CCCAATGGCA GGCGAAAATC


 


1501
GGCATCATCC CCGTCAAATC TTGA






This corresponds to the amino acid sequence <SEQ ID 222; ORF 050-1.a>:










a050-1.pep




1
MTVIKQEDFI QSICDAFQFI SYYHPKDYID ALYKAWQKEE NPAAKDAMTQ


 


51
ILVNSRMCAE NNRPICQDTG IATVFLKVGM DVQWDADMSV EEMVNEGVRR


 


101
AYTWEGNTLR ASVLADPAGK RQNTKDNTPA VIHMSIVPGD KVEVTCAAKG


 


151
GGSENKSKLA MLNPSDNIVD WVLKTIPTMG AGWCPPGILG IGIGGTPEKA


 


201
VLMAKESLMS HIDIQELQEK AASGAELSTT EALRLELFEK VNALGIGAQG


 


251
LGGLTTVLDV KILDYPTHAA SKPIAMIPNC AATRHVEFEL DGSGPVELTP


 


301
PRVEDWPDLT YSPDNGKRVD VDKLTKEEVA SWKTGDVLLL NGKILTGRDA


 


351
AHKRLVDMLD KGEELPVDFT NRLIYYVGPV DPVGDEIVGP AGPTTATRMD


 


401
KFTRQMLEQT DLLGMIGKSE RGAATCEAIA DNKAVYLMAV GGAAYLVAKA


 


451
IKSSKVLAFP ELGMEAIYEF EVKDMPVTVA VDSKGESIHA TAPPQWQAKI


 


501
GIIPVKS*






a050-1/m050-1 98.4% identity in 507 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 223>:










g052.seq




1
ATGGCTTTGG TGGCGGAGGA AACGGAAATA TCCGCGCCGT GTTTCAAAGG


 


51
CTGCGAGCCG ACGGGCGACA GCAGGCTGTT GTCCACCACC AAGAGCGCGC


 


101
CGATGCCGTG CGCCAATTCC GCCAAGGCTT CCAAGTCGGC CACTTCGCCC


 


151
AAGGGGTTGG ACGGCGTTTC CAAAAACAGC AGTTTGGTGT TGGCTTTGAC


 


201
GGCGGCTTTC CATTCATTTA TATCAGTCGG CGACACGCGG CTCACTCCGA


 


251
TGCCGAATTT GGTAACGATG TTATTGATAA AGCCGACGGT CGTGCCGAAC


 


301
AGGCTGCGGC TGGAAACCAC ATGGTCGCCC GCCTGCAGGA AGGTGAAAAA


 


351
CGCCGCCTGA






This corresponds to the amino acid sequence <SEQ ID 224; ORF 052.ng>:










g052.pep




1
MALVAEETEI SAPCFKGCEP TGDSRLLSTT KSAPMPCANS AKASKSATSP


 


51
KGLDGVSKNS SLVLALTAAF HSFISVGDTR LTPMPNLVTM LLIKPTVVPN


 


101
RLRLETTWSP ACRKVKNAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 225>:










m052.seq




1
ATGGCTTTGG TGGCGGAGGA AACGGAAATA TCCGCGCCGT GTTTCAAAGG


 


51
CTGCGAGCCG ACGGGCGACA GCAGGCTGTT GTCCACCACC AAGAGCGCGC


 


101
CGATGCCGTG CGCCAATTCC GCCAAGGCTT CCAAGTCGGC CACTTCGCCC


 


151
AAGGGGTTGG ACGGCGTTTC CAAAAACAGC AGTTTGGTGT TGGCTTTGAC


 


201
GGCGGCTTTC CATTCATTTA TATCAGTCGG CGACACGCGG CTCACTCCGA


 


251
TGCCGAATTT GGTAACGATG TTATTGATAA AGCCGACGGT CGTGCCGAAC


 


301
AGGCTGCGGC TGGAAACCAC ATGGTCGCCC GCCTGCAGGA AGGTGAAAAA


 


351
CGCCGCCTGA






This corresponds to the amino acid sequence <SEQ ID 226; ORF 052>:










m052.pep




1
MALVAEETEI SAPCFKGCEP TGDSRLLSTT KSAPMPCANS AKASKSATSP


 


51
KGLDGVSKNS SLVLALTAAF HSFISVGDTR LTPMPNLVTM LLIKPTVVPN


 


101
RLRLETTWSP ACRKVKNAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 227>:










a052.seq




1
ATGGCTTTGG TCGCGGAGGA AACGGAAATA TCCGCGCCGT GTTTCAAAGG


 


51
CTGAGAGCCG ACAGGCGACA GCAGGCTGTT GTCCACCACC AAGAGCGCGC


 


101
CGATGCCGTG CGCCAATTCC GCCAAGGCTT CCAAGTCGGC CACTTCTCCC


 


151
AAGGGATTGG ACGGCGTTTC CAAAAACAGC AGTTTGGTGT TGGCTTTGAC


 


201
GGCGGCTTTC CATTCGTTTA TATCAGTCGG CGACACGTGA CTCACTTCGA


 


251
TGCCGAATTT GGTAACGATG TTATTGATAA AGCCGACGGT CGTGCCGAAC


 


301
AGGCTGCGGC TGGAAATCAC ATGGTCGCCC GCCTGCAAAA AGGTGAAAAA


 


351
CGCCGCCTGA






This corresponds to the amino acid sequence <SEQ ID 228; ORF 052.a>:










a052.pep




1
MALVAEETEI SAPCFKG*EP TGDSRLLSTT KSAPMPCANS AKASKSATSP


 


51
KGLDGVSKNS SLVLALTAAF HSFISVGDT* LTSMPNLVTM LLIKPTVVPN


 


101
RLRLEITWSP ACKKVKNAA*






m052/a052 95.8% identity over a 119 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 052 shows 95.8% identity over a 119 aa overlap with a predicted ORF (ORF 052.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 229>:










g073.seq




1
ATGTGTATGC CATACGCAAT AAGGGTTTCA GACGGCATCT GCCGCATTTT


 


51
TCCGCCGATG CCGTCTGAAA CACGCAATCA GCGCGCGAGT GCCTGTTTCA


 


101
AATCGTCAAT CAAATCGCCA ACATATTCCA AACCGACCGA CAGGCGCACC


 


151
AGTCCGGGGC GGatacCGGC GGCGAGTTTT TCTTCGGGCT GCATCCTGCC


 


201
GTGCGTGGTT GTCCACGGAT TGGTGATGGT CGAGCGCACG TCGCCGAGGT


 


251
TGGCGGTACG GGAAAAGAGT TCCACGACTT TCCACGCGGC TGCTTGGTCG


 


301
GCGACTTCAA AACCGATGAC GATGCCGCCG CCGTTTTGCT GTTTGCGGAT


 


351
AAGCTCCGCC TGCGGATGGT CGGGCAATCC GGTGTAG






This corresponds to the amino acid sequence <SEQ ID 230; ORF 073.ng>:










g073.pep




1
MCMPYAIRVS DGICRIFPPM PSETRNQRAS ACFKSSIKSP TYSKPTDRRT


 


51
SPGRIPAASF SSGCILPCVV VHGLVMVERT SPRLAVREKS STTFHAAAWS


 


101
ATSKPMTMPP PFCCLRISSA CGWSGNPV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 231>:










m073.seq




1
ATGTGTATGC CATATAAGAT AAGGGTTTCA GACGGCATCT GCTGTCCAAT


 


51
GCCGTCTGAA ACACGCAATC AGCGTGCGAG TGCCTGTTTC AAATCGTCAA


 


101
TCAAATCGCC AACATATTCC AAACCGACCG ACAGGCGCAC CAATCCGGGG


 


151
CGGATGTTGG CGGCGAGTTT TTCTTCGGGC TGCATCCTGC CGTGCGTGGT


 


201
TGTCCACGGG TGGGTAATGG TCGAGCGCAC GTCACCGAGG TTGGCGGTGC


 


251
GGGAAAAGAG TTCCACGCCG TCCACAACTT TCCACGCCGC TTCTTGATCG


 


301
GCAACTTCAA AGCCGATGAC GATGCCGCCG CCGTTTTGCT GTTTGCGGAT


 


351
AAGCGCCGCC TGAGGATGGT CGGACAATCC GGTGTAG






This corresponds to the amino acid sequence <SEQ ID 232; ORF 073>:










m073.pep




1
MCMPYKIRVS DGICCPMPSE TRNQRASACF KSSIKSPTYS KPTDRRTNPG


 


51
RMLAASFSSG CILPCVVVHG WVMVERTSPR LAVREKSSTP STTFHAASXS


 


101
ATSKPMTMPP PFCCLRISAA XGWSDNPV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 233>:










a073.seq




1
ACGTGTATGT CATATAAGAT AAGGGTTTCA GACGGCATTT GCGGTGTTTT


 


51
TCCGCCGATG CCGTCTGAA. CACGCAATCA GCGCGCGAGT GCCTGTTTCA


 


101
AATCGTCAAT CAAATCGCCA ACATATTCCA AACCGACCGA CAGGCGCACC


 


151
AATCCGGGGC GGATGTTGGC GGCGAGTTTT TCTTCGGGCT GCATCCTGCC


 


201
GTGCGTGGTT GTCCACGGAT GGGTAATGGT CGAGCGCACG TCGCCGAGGT


 


251
TGGCGGTACG GGAGAAAAGT TCGACGCCGT CCACGACTTT CCACGCGGCT


 


301
GCTTGGTCGG CGACTTCAAA GCCGATGACG ATGCCGCCGC CGTTTTGCTG


 


351
TTTGCGGATA AGCTCCGCCT GAGGATGGTC GGGTAATCCG GTGTAA






This corresponds to the amino acid sequence <SEQ ID 234; ORF 073.a>:










a073.pep




1
TCMSYKIRVS DGICGVFPPM PSEXRNQRAS ACFKSSIKSP TYSKPTDRRT


 


51
NPGRMLAASF SSGCILPCVV VHGWVMVERT SPRLAVREKS STPSTTFHAA


 


101
AWSATSKPMT MPPPFCCLRI SSA*GWSGNP V*






m073/a073 92.3% identity over a 130 aa overlap





Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 073 shows 87.0% identity over a 131 aa overlap with a predicted ORF (ORF 073.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 235>:










g075.seq




1
ATGCCGCCTT ACTTCATCAC CCTCTTAACG ATGGAAAATA CAAAAAGCGC


 


51
GGCGAAAACG CCCACTACAA TCCAACCGGC TTCCATACCG TCCGCTTTTG


 


101
CGGCTTCCAA AGCGTTTTTT GCCGTTTCGG GCAACGCTGC GTTTGCCTGT


 


151
GCCGCCAAAG CCAGCGGGGC GGCTGTTACA ACAGCCAGTT TTGCGCCGTA


 


201
TTTACGGCAG GTGTTAATAA ATTTCATGAT ATTTTCCTTT ACGAAATTTT


 


251
TAAAAAAATG TGTTTGCGGG CTTTGTGAAG GTTTTAGAGA CCGCCTGCCG


 


301
GGCCTCTTAA ACTTAATCTT CTTTTTCGTA GAATCCGAAA ATTACAAATT


 


351
CCCCGCCTAT CTCTTCCAAT GCCGAGCTAA AAGCGTCTTC ATAGCTGTCA


 


401
TATTTACCGG CTGA






This corresponds to the amino acid sequence <SEQ ID 236; ORF 075.ng>:










g075.pep




1
MPPYFITLLT MENTKSAAKT PTTIQPASIP SAFAASKAFF AVSGNAAFAC


 


51
AAKASGAAVT TASFAPYLRQ VLINFMIFSF TKFLKKCVCG LCEGFRDRLP


 


101
GLLNLIFFFV ESENYKFPAY LFQCRAKSVF IAVIFTG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 237>:










m075.seq




1
ATGCCGTCTT ACTTCATCAC TCTCTTAACG ATGGAAAATA CAAAAAGCGC


 


51
GGCGAAAATG CCCACTACAA TCCAACCGGC TTCCATACCG TCCGCTTTTG


 


101
CGGCTTCCAA AGCGTTTTTT GCCGTATCGG GCAACGTTGC ATTTGCATGT


 


151
GCGGCCAAAG CCAGGGGAGC AGCTGTTACA ACAGCCAGTT TTGCGCCGTA


 


201
TTTACGGCAG GTGTTAATAA ATTTCATGAT ATTTTCCTTC AAAAAGTGTT


 


251
TGGCGGTAAT GGATGGAGCG TTTTTCAGAC GACCGCCGAA CATCCGAAAA


 


301
TCAGTCTTTC AAAAATCCGA ATACGACAAA TTCGTATTGG TTGCCGATTT


 


351
CTTCCAAACC TGCGTTAATC GCTTCTTCGA AGTCGTAGAA ATAATCGGCA


 


401
TTGGTGATTA A






This corresponds to the amino acid sequence <SEQ ID 238; ORF 075>:










m075.pep




1
MPSYFITLLT MENTKSAAKM PTTIQPASIP SAFAASKAFF AVSGNVAFAC


 


51
AAKARGAAVT TASFAPYLRQ VLINFMIFSF KKCLAVMDGA FFRRPPNIRK


 


101
SVFQKSEYDK FVLVADFFQT CVNRFFEVVE IIGIGD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 075 shows 65.7% identity over a 137 aa overlap with a predicted ORF (ORF 075.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 239>:










a075.seq




1
ATGCCGTCTT ACTTCATCAC TCTCTTAACG ATGGAAAAGA CAAAAAGCGC


 


51
GGCGAAAACG CCCACTACAA TCCAACCGGC TTCCATACCG TCCGCTTTTG


 


101
CGGCTTCCAA AGCGTTTTTT GCTGTATCGG GCAACGTTGC ATTTGCATGT


 


151
GCGGCCAAAG CCAGGGGAGC AGCTGTTACA ACAGCCAGTT TTGCGCCGTA


 


201
TTTACGGCAG GTGTTAATAA ATTTCATGAT ATTTTCCTTC AAAAAGTGTT


 


251
TGGCGGTAAT GGATGGAGCG TTTTTCAGAC GACCGCCGAA CATCCGAAAA


 


301
TCAGTCTTTC AAAAATCCGA ATACGACAAA TTCGTATTGG TTGCCGATTT


 


351
CTTCCAAACC TGCGTTAATC GCTTCTTCGA AGTCGTAGAA ATAATCGGCA


 


401
TTGGTGATTA A






This corresponds to the amino acid sequence <SEQ ID 240; ORF 075.a>:










a075.pep




1
MPSYFITLLT MEKTKSAAKT PTTIQPASIP SAFAASKAFF AVSGNVAFAC


 


51
AAKARGAAVT TASFAPYLRQ VLINFMIFSF KKCLAVMDGA FFRRPPNIRK


 


101
SVFQKSEYDK FVLVADFFQT CVNRFFEVVE IIGIGD*






m075/a075 98.5% identity over a 136 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 241>:










g080.seq




1
ATGTGGGATA ATGCCGAAGC GATGGAACGG CTGACGCGCT GGCTGCTTGT


 


51
CATGATGGCG ATGCTGCTTG CTGCGTCCGG GCTGGTTTGG TTTTACAATT


 


101
CGAATCATCT GCCCGTCAAG CAGGTGTCGC TGAAGGGCAA CCTGGTTTAT


 


151
TCCGATAAGA AGGCATTGGG CAGTTTGGCG AAAGAATACA TCCATGGGAA


 


201
TATTTTGAGG ACGGACATCA ATGGCGCACA GGAAGCCTAC CGCCGGTATC


 


251
CGTGGATTGC GTCGGTCATG GTGCGCCGCC GTTTTCCCGA TACGGTTGAG


 


301
GTCGTCCTGA CCGAGCGCAA GCCGGTTGCA CGTTGGGGCG ACCATGCCTT


 


351
GGTGGACGGC GAAGGCAATG TTTTTGAAGC CCGCTTGGAC AGACCCGGAA


 


401
TGCCGGTATT CAGAGGCGCG GAAGGAACGT CTGCCGAAAT GCTCCGCCGT


 


451
TATGACGAAT TTTCGACTGT TTTGGCAAAA CAGGGTTTGG GCATCAAAGA


 


501
GATGACCTAT ACGGCACGTT CGGCGTGGAA TGTCGTTTTG GACAACGGCA


 


551
TCACCGTCAG GCTCGGACGG GAAAAcgaGA TGAAACGCCT CCgGCTTTTT


 


601
ACcgAAGCGT GGCAGCATCT gttgcGTAAG AATAAAAATC GGTTATCCTA


 


651
TGTGGATATG Aggtataagg acggatttTC agtcccccat gctCCCGACG


 


701
GTTTACCCGA AAAAGAATcc gAAGAATatt gggaacaggt ttgggacata


 


751
ttacggcctg gcgtcggaaa cggttcgacg caaatttcaa tcagttatAA


 


801
GGGCAGacga acaatggaac AGcagtaa






This corresponds to the amino acid sequence <SEQ ID 242; ORF 080.ng>:










g080.pep




1
MWDNAEAMER LTRWLLVMMA MLLAASGLVW FYNSNHLPVK QVSLKGNLVY


 


51
SDKKALGSLA KEYIHGNILR TDINGAQEAY RRYPWIASVM VRRRFPDTVE


 


101
VVLTERKPVA RWGDHALVDG EGNVFEARLD RPGMPVFRGA EGTSAEMLRR


 


151
YDEFSTVLAK QGLGIKEMTY TARSAWNVVL DNGITVRLGR ENEMKRLRLF


 


201
TEAWQHLLRK NKNRLSYVDM RYKDGFSVPH APDGLPEKES EEYWEQVWDI


 


251
LRPGVGNGST QISISYKGRR TMEQQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 243>:










m080.seq




1
ATGTGGGATA ATGCCGAAGC GATGGAACGG CTGACGCGCT GGCTGCTTGT


 


51
CATGATGGCG ATGCTGCTTG CTGCGTCCGG GCTGGTTTGG TTTTACAATT


 


101
CGAATCATCT GCCCGTCAAG CAGGTGTCGC TGAAGGGCAA CCTGGTTTAT


 


151
TCCGATAAGA AGACATTGGG CAGTTTGGCG AAAGAATACA TCCATGGGAA


 


201
TATTTTGAGG ACGGACATCA ATGGCGCACA GGAGGCCTAC CGCCGGTATC


 


251
CGTGGATTGC GTCGGTCATG GTGCGCCGCC GTTTTCCCGA CACGGTTGAG


 


301
GTCGTCCTGA CCGAGCGCAA GCCGGTCGCG CGTTGGGGCG ACCATGCCTT


 


351
GGTGGACGGC GAAGGCAATG TTTTTGAAGC CCGCTTGGAC AGACCCGGAA


 


401
TGCCGGTATT CAGAGGCGCG GAAGGAACGT CTGCCGAAAT GCTCCGCCGT


 


451
TATGACGAAT TTTCGACTGT TTTGGCAAAA CAGGGTTTGG GCATCAAAGA


 


501
GATGACCTAT ACGGCACGTT CGGCGTGGAT TGTCGTTTTG GACAACGGCA


 


551
TCACCGTCAG GCTCGGACGG GAAAACGAGA TGAAACGCCT CCGGCTTTTT


 


601
ACCGAAGCGT GGCAGCATCT GTTGCGTAAA AATAAAAATC GGTTATCCTA


 


651
TGTGGATATG AGGTATAAGG ACGGATTTTC AGTCCGCTAT GCTTCCGACG


 


701
GTTTACCCGA AAAAGAATCC GAAGAATAG






This corresponds to the amino acid sequence <SEQ ID 2441; ORF 080>:










m080.pep




1
MWDNAEAMER LTRWLLVMMA MLLAASGLVW FYNSNHLPVK QVSLKGNLVY


 


51
SDKKTLGSLA KEYIHGNILR TDINGAQEAY RRYPWIASVM VRRRFPDTVE


 


101
VVLTERKPVA RWGDHALVDG EGNVFEARLD RPGMPVFRGA EGTSAEMLRR


 


151
YDEFSTVLAK QGLGIKEMTY TARSAWIVVL DNGITVRLGR ENEMKRLRLF


 


201
TEAWQHLLRK NKNRLSYVDM RYKDGFSVRY ASDGLPEKES EE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 080 shows 97.9% identity over a 242 aa overlap with a predicted ORF (ORF 080.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 245>:










a080.seq




1
ATGTGGGATA ATGCCGAAGC GATGGAACGG CTGACGCGCT GGCTGCTTGT


 


51
CATGATGGCG ATGCTGCTTG CTGCGTCCGG GCTGGTTTGG TTTTACAATT


 


101
CGAATCATCT GCCCGTCAAG CAGGTGTCGC TGAAGGGCAA CCTAGTTTAT


 


151
TCCGATAAGA AAGCATTGGG CAGTTTGGCG AAAGAATACA TCCATGGGAA


 


201
TATTTTGAGG ACGGACATCA ATGGCGCACA GGAGGCCTAC CGCCGGTATC


 


251
CGTGGATTGC GTCGGTCATG GTGCGCCGCC GTTTTCCCGA CACGGTTGAG


 


301
GTCGTCCTGA CCGAGCGCAA GCCGGTCGCG CGTTGGGGCG ACCATGCCTT


 


351
GGTGGACGGC GAAGGCAATG TTTTTGAAGC CCGTTTGGAC AGACCCGGAA


 


401
TGCCGGTATT CAGAGGCGCG GAAGGAACGT CTGCCGAAAT GCTCCGCCGT


 


451
TATGACGAAT TTTCGACTGT TTTGGCAAAA CAGGGTTTGG GCATCAAAGA


 


501
GATGACCTAT ACGGCACGTT CGGCGTGGAT TGTCGTTTTG GACAACGGCA


 


551
TCACCGTCAG GCTCGGACGG GAAAACGAGA TGAAACGCCT CCGGCTTTTT


 


601
ACCGAAGCGT GGCAACATCT GTTGCGTAAA AATAAAAATC GGTTATCCTA


 


651
TGTGGATATG AGGTATAAGG ACGGATTTTC AGTCCGCTAT GCTCCCGACG


 


701
GTTTACCCGA AAAAGAATCC GAAGAATAG






This corresponds to the amino acid sequence <SEQ ID 246; ORF 080.a>:










a080.pep




1
MWDNAEAMER LTRWLLVMMA MLLAASGLVW FYNSNHLPVK QVSLKGNLVY


 


51
SDKKALGSLA KEYIHGNILR TDINGAQEAY RRYPWIASVM VRRRFPDTVE


 


101
VVLTERKPVA RWGDHALVDG EGNVFEARLD RPGMPVFRGA EGTSAEMLRR


 


151
YDEFSTVLAK QGLGIKEMTY TARSAWIVVL DNGITVRLGR ENEMKRLRLF


 


201
TEAWQHLLRK NKNRLSYVDM RYKDGFSVRY APDGLPEKES EE*






m080/a080 99.2% identity over a 242 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 247>:










g081.seq




1
ATGAAACCAC TGGACCTAAA TTTCATCTGC CAAGCCCTCA AGCTTCCGAT


 


51
GCCGTCTGAA AACAAACCCG TGTCGCGCAT CGTAACCGAC AGCCGCGATA


 


101
TTCGGGAAGG CGATGTGTTT TTCGCATTGG CGGGCGGGCG GTTTGACGCG


 


151
CATGATTTTG TTGGAGGCGT ATTGTCTGCG GGCGCGGCGG CGGTTGTGGT


 


201
TTCGCGCGAA GATTGCGCGG CTTTGGGCGG CGCGTTGAAA GTCGATGACA


 


251
CGCTTGCCGC GTTGCAAACG TTGGCGAAGG CGTGGCGCGA TAATGTGAAC


 


301
CCGTTTGTGT TCGGCATTAC CGGTTCGGGC GGCAAGACGA CGGTGAAGGA


 


351
GATGCTGGCT GCGGTATTGC GCCGCCGTTT CGGCGATGAT GCCGTTTCGG


 


401
CGACGGCAGG CAACTTCAAC AACCACAtcg gaTTGCCGCT GACTTTATTG


 


451
AAATtaaAcg aAAAACACCG CTATGCCGTG ATTGAAATGG GCATGAACCA


 


501
TTTTGGcgaa ctggcggtTt taacgcaaaT CGCCAAACCC GATGCCGCTT


 


551
TGGtcaACAA CGCCCTGCGC GCCCATGTCG GATGCGGTTt cgacggagtg


 


601
GGCGATATTG CCAAAGcgaa aagcGAGATT TatgcagGct tATGTTCAGA


 


651
CGGCATGGCA CTGATTCCTC AAGAAGATGC CAATATGGCT GTCTTCAAAA


 


701
CGGCAACGTT TAATTTGAAT ACGTGCACTT TCGGCGTCGA TAGCGGCGAT


 


751
GTCCGCGCGG AAAATATCGT GCTGAAACCT TTGTCGTGCG AATTTGATTT


 


801
GGTGTGCGGC GACGAGCGCA CTGCCGTGGT GCTGCCTGTT CCCGGCCGCC


 


851
ACAATGTCCA CAACGCCGCC GCTGCCGCCG CGCTGGCTTT GGCTGCCGGT


 


901
TTGAGTTTGA ACGATGTGGC GGAAGGTTTG CAAGGCTTCA GCAACATCAA


 


951
AGGCCGTCTG AACGTCAAAG CCGGCATCAA GGGCGCAACC CTGATTGACG


 


1001
ATACTTATAA TGCGAATCCC GACAGTATGA AAGCCGCGGT TGACGTGTTG


 


1051
GCGCGTATGC CTGCGCCGCG CATTTTCGTG ATGGGCGATA TGGGCGAACT


 


1101
GGGCGAGGAc gaAGCCGCCG CCATGCACGC CGAagtcgGC GCGTACGCCC


 


1151
GCGACCAAGG CATCGAAGCG GCTTATTTTG TCGGCGACAA CAGCGTCGAA


 


1201
GCGGcggaAA AATTTGGCGC GGACGGTTTG TGGTTCGCCG CCAAAGACCC


 


1251
GTTGATTCAA GTGTTGAGCC ACGATTTGCC CGAACGCGCC ACCGTGTTGG


 


1301
TGAAAGGTTC GCGCTTTATG CAGAtggAAG AAGTGGTCGA GGCATTGGAG


 


1351
GATAAGTga






This corresponds to the amino acid sequence <SEQ ID 248; ORF 081.ng>:










g081.pep




1
MKPLDLNFIC QALKLPMPSE NKPVSRIVTD SRDIREGDVF FALAGGRFDA


 


51
HDFVGGVLSA GAAAVVVSRE DCAALGGALK VDDTLAALQT LAKAWRDNVN


 


101
PFVFGITGSG GKTTVKEMLA AVLRRRFGDD AVSATAGNFN NHIGLPLTLL


 


151
KLNEKHRYAV IEMGMNHFGE LAVLTQIAKP DAALVNNALR AHVGCGFDGV


 


201
GDIAKAKSEI YAGLCSDGMA LIPQEDANMA VFKTATFNLN TCTFGVDSGD


 


251
VRAENIVLKP LSCEFDLVCG DERTAVVLPV PGRHNVHNAA AAAALALAAG


 


301
LSLNDVAEGL QGFSNIKGRL NVKAGIKGAT LIDDTYNANP DSMKAAVDVL


 


351
ARMPAPRIFV MGDMGELGED EAAAMHAEVG AYARDQGIEA AYFVGDNSVE


 


401
AAEKFGADGL WFAAKDPLIQ VLSHDLPERA TVLVKGSRFM QMEEVVEALE


 


451
DK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 249>:










m081.seq




1
ATGAAACCAC TGGACCTAAA TTTCATCTGC CAAGCCCTCA AGCTTCCGAT


 


51
GCCGTCTGAA AGCAAACCCG TGTCGCGCAT CGTAACCGAC AGCCGCGACA


 


101
TCCGCGCGGG CGATGTGTTT TTCGCATTGG CGGGCGAGCG GTTTGACGCG


 


151
CATGATTTTG TTGAAGACGT ATTGGCTGCT GGTGCGGCGG CGGTTGTGGT


 


201
TTCGCGCGAA GATTGTGCTG CAATGGATGG CGCGTTGAAA GTCGATGACA


 


251
CGCTTGCCGC ATTGCAAACG CTGGCAAAGG CGTGGCGTGA AAATGTGAAT


 


301
CCGTTTGTGT TCGGCATTAC CGGTTCGGGC GGCAAGACGA CGGTGAAGGA


 


351
AATGCTGGCT GCGGTATTGC GCCgCCGTTT CGGCGATGAT GCCGTGTTGG


 


401
CGACGGCAGG CAACTTCAAC AACCATATCG GATTGCCGCT GACTTTGTTG


 


451
AAGTTAAACG AAAAACACCG CTATGCCGTG ATTGAAATGG GCATGAACCA


 


501
TTTCGGCGAA CTGGCGGTTT TAACGCAmAT CGCCAAACCA AATGCCGCAT


 


551
TGGTCAACAA CGCCATGCGC GCCCATGTCG GCTGCGGTTT CGACGGAGTG


 


601
GGCGATATTG CCAAAGCGAA AAGCGAGATT TACCAAGGTT TATGTTCAGA


 


651
CGGCATTGCA CTGATTCCTC AAGAAGATGC CAATATGGCT GTCTTCAAAA


 


701
CGGCAACGCT TAATTTGAAT ACGCGCACTT TCGGCATCGA TAGCGGCGAT


 


751
GTTCACGCGG AAAATATTGT GCTGAAACCG TTGTCGTGCG AATTTGATTT


 


801
GGTGTGCGGC GATGAGCGCG CCGCCGTGGT GCTGCCTGTT CCCGGCCGCC


 


851
ACAATGTCCA CAACGCCGCC GCTGCCGCCG CGCTGGCTTT GGCTGCGGGT


 


901
TTGAGTTTGA ACGATGTGGC GGAAGGTTTG AAAGGCTTCA GCAATATCAA


 


951
AGGCCGTCTG AACGTCAAAT CCGGAATCAA GGGCGCAACC CTGATTGACG


 


1001
ATACTTATAA TGCGAACCCT GACAGCATGA AAGCTGCGAT TGACGTGTTG


 


1051
GCGCGTATGC CTGCGCCGCG TATTTTCGTG ATGGGCGATA TGGGCGAACT


 


1101
GGGCGAACTG GGCGAGGACG AAGCCGCCGC TATGCACGCC GAAGTCGGCG


 


1151
CGTATGCCCG CGACCAAGGC ATCGAAGCGG CTTATTTTGT CGGCGACAAC


 


1201
AGCGTCGAAG CGGCGGAAAA ATTTGGCGCG GACGGTTTGT GGTTCGCCGC


 


1251
CAAAGACCCG TTGATTCAAG TGTTGCGCCA CGATTTGCCC GAACGCGCCA


 


1301
CCGTGTTGGT GAAAGGTTCG CGCTTTATGC AGATGGAAGA AGTGGTCGAG


 


1351
GCATTGGAGG ATAAGTGA






This corresponds to the amino acid sequence <SEQ ID 250; ORF 081>:










m081.pep




1
MKPLDLNFIC QALKLPMPSE SKPVSRIVTD SRDIRAGDVF FALAGERFDA


 


51
HDFVEDVLAA GAAAVVVSRE DCAAMDGALK VDDTLAALQT LAKAWRENVN


 


101
PFVFGITGSG GKTTVKEMLA AVLRRRFGDD AVLATAGNFN NHIGLPLTLL


 


151
KLNEKHRYAV IEMGMNHFGE LAVLTXIAKP NAALVNNAMR AHVGCGFDGV


 


201
GDIAKAKSEI YQGLCSDGIA LIPQEDANMA VFKTATLNLN TRTFGIDSGD


 


251
VHAENIVLKP LSCEFDLVCG DERAAVVLPV PGRHNVHNAA AAAALALAAG


 


301
LSLNDVAEGL KGFSNIKGRL NVKSGIKGAT LIDDTYNANP DSMKAAIDVL


 


351
ARMPAPRIFV MGDMGELGEL GEDEAAAMHA EVGAYARDQG IEAAYFVGDN


 


401
SVEAAEKFGA DGLWFAAKDP LIQVLRHDLP ERATVLVKGS RFMQMEEVVE


 


451
ALEDK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 081 shows 94.1% identity over a 455 aa overlap with a predicted ORF (ORF 081.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 251>:










a081.seq




1
ATGAAACCAC TGGACCTAAA TTTCATCTGC CAAGCCCTCA AGCTTCCGAT


 


51
GCCGTCTGAA AGCAAACCCG TGTCGCGCAT CGTAACCGAC AGCCGCGACA


 


101
TCCGCGCGGG CGATGTGTTT TTCGCATTGG CGGGCGGGCG GTTTGATGCG


 


151
CATGATTTTG TTGAAGACGT ATTGGCTGCG GGTGCGGCGG CGGTTGTGGT


 


201
TTCGCGCGAA GATTGCGTTG CAATGGATGG CGCGTTGAAA GTCGATGACA


 


251
CGCTTACCGC GTTGCAAATG TTGGCGAAGG CGTGGCGCGA GAATGTGAAC


 


301
CCGTTTGTGT TCGGTATTAC CGGCTCGGGC GGCAAGACGA CGGTGAAGGA


 


351
AATGTTGGCT GCGGTATTGC GCCGCCGTTT CGGCGATAAT GCCGTTTTGG


 


401
CGACGGCAGG CAACTTCAAC AACCACATCG GATTGCCGTT GACTTTGTTG


 


451
AAATTAAACG AAAAACACCG CTATGCCGTG ATTGAAATGG GTATGAACCA


 


501
TTTTGGCGAA CTGGCGGTTT TGACACAAAT CGCCAAACCC GATGCCGCAT


 


551
TGGTCAACAA CGCCATGCGC GCCCATGTCG GCTGCGGTTT CGACGGAGTG


 


601
GGCGATATTG CCAAAGCGAA AAGCGAGATT TATCAAGGCT TATGTTCAGA


 


651
CGGCATGGCG CTGATTCCTC AAGAAGATGC CAATATGGCT GTCTTCAAAA


 


701
CGGCAACGCT TAATTTGAAT ACGCGCACTT TCGGCATCGA TAGCGGCGAT


 


751
GTCCACGCGG AAAATATCGT GCTGAAACCG TTGTCGTGCG AATTTGATTT


 


801
GGTGTGCGGC AACGAGTGCG CAGCCGTGGT TCTGCCCGTT CCCGGCCGCC


 


851
ACAATGTCCA CAACGCCGCC GCCGCCGCCG CGCTGTCTTT GGCTGCAGGT


 


901
TTGAGTTTGA ACGATGTGGC GGAAGGTTTG AAAGGCTTCA GCAATATCAA


 


951
AGGCCGTCTG AACGTCAAAT CCGGAATCAA GGGCGCAACC CTGATTGACG


 


1001
ATACTTATAA TGCGAACCCT GACAGCATGA AAGCTGCGGT TGACGTGTTG


 


1051
GCGCGTATGC CTGCGCCGCG TATTTTCGTG ATGGGCGATA TGGGCGAACT


 


1101
GGGTGAGGAC GAAGCCGCCG CCATGCACGC CGAAGTCGGC GCGTACGCCC


 


1151
GCGACCAAGG CATCGAAGCG GCTTATTTTG TCGGCGACAA CAGCGTCGAA


 


1201
GCGGCGGAAA AATTTGGCGC GGACGGTTTG TGGTTCGCCG CCAAAGACCC


 


1251
GTTGATTCAA GTGTTGCGCC ACGATTTGCC CGAACGCGCC ACCGTGTTGG


 


1301
TGAAAGGTTC GCGCTTTATG CAGATGGAAG AAGTGGTCGA GGCATTGGAG


 


1351
GATAAGTGA






This corresponds to the amino acid sequence <SEQ ID 252; ORF 081.a>:










a081.pep




1
MKPLDLNFIC QALKLPMPSE SKPVSRIVTD SRDIRAGDVF FALAGGRFDA


 


51
HDFVEDVLAA GAAAVVVSRE DCVAMDGALK VDDTLTALQM LAKAWRENVN


 


101
PFVFGITGSG GKTTVKEMLA AVLRRRFGDN AVLATAGNFN NHIGLPLTLL


 


151
KLNEKHRYAV IEMGMNHFGE LAVLTQIAKP DAALVNNAMR AHVGCGFDGV


 


201
GDIAKAKSEI YQGLCSDGMA LIPQEDANMA VFKTATLNLN TRTFGIDSGD


 


251
VHAENIVLKP LSCEFDLVCG NECAAVVLPV PGRHNVHNAA AAAALSLAAG


 


301
LSLNDVAEGL KGFSNIKGRL NVKSGIKGAT LIDDTYNANP DSMKAAVDVL


 


351
ARMPAPRIFV MGDMGELGED EAAAMHAEVG AYARDQGIEA AYFVGDNSVE


 


401
AAEKFGADGL WFAAKDPLIQ VLRHDLPERA TVLVKGSRFM QMEEVVEALE


 


451
DK*






m081/a081 96.7% identity over a 455 aa overlap





The following partial DNA sequence was identified in N. Gonorrhoeae <SEQ ID 253>:










g082.seq




1
aTGTGGTTGT TGAAGTTGCC TGCCGTCGCC GAAACGGCAT CATCGCCGAA


 


51
ACGGCGGCGC AATACCGCAG CCAGCATCTC CTTCACCGTC GTCTTGCCGC


 


101
CCGAACCGGT AATGCCGAAC ACAAACGGGT TCACATTATC GCGCCACGCC


 


151
TTCGCCAACG TTTGCAACGC GGCAAGCGTG TCATCGACTT TCAACGCGCC


 


201
GCCCAAAGCC GCGCAATCTT CGCGCGAAAC CACAACCGCC GCCGCGCCCG


 


251
CAGACAATAC GCCTCCAACA AAATCATGCG CGTCAAACCG CCCGCCCGCC


 


301
AATGCGAAAA ACACATCGCC TTCCCGAATA TCGCGGCTGT CGGTTACGAT


 


351
GCGCGACACG GGTTTGTTTT CAGACGGCAT CGGAAGCTTG AGGGCTTGGC


 


401
AGATGAAATT TAGGTCCAGT GGTTTCATAT TTGCTTTCGT TAATATTCGG


 


451
GCGGCGGACA CATCGGTAGC GGCTGATTTT TTTATCGCCT GTTTTGCTGT


 


501
GGTAAAACAC AGATTATTTT CCCATTCTCA TTCGGCATTT TTTCTGTACG


 


551
TATCATTTTT TAGACGTATT TTTAGCCGAT TTGCCTTTTC CCGCATACCA


 


601
CGGCGCGGGG TCGTCGGACT GTCTGTCGAT AAAGGCAAGG TTATTGCCTT


 


651
CGCCCGGCAC ATCGGGGACA TTCCCCCAAA AATCATAGCC GTCATCGGGC


 


701
AACTCGTCGG TTTCGATACC CGTCCAACTG CCGAATCCGC GTAA






This corresponds to the amino acid sequence <SEQ ID 254; ORF 082.ng>:










g082.pep




1
MWLLKLPAVA ETASSPKRRR NTAASISFTV VLPPEPVMPN TNGFTLSRHA


 


51
FANVCNAASV SSTFNAPPKA AQSSRETTTA AAPADNTPPT KSCASNRPPA


 


101
NAKNTSPSRI SRLSVTMRDT GLFSDGIGSL RAWQMKFRSS GFIFAFVNIR


 


151
AADTSVAADF FIACFAVVKH RLFSHSHSAF FLYVSFFRRI FSRFAFSRIP


 


201
RRGVVGLSVD KGKVIAFARH IGDIPPKIIA VIGQLVGFDT RPTAESA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 255>:










m082.seq




1
ATGnnGTTGT TGAAGTTGCC TGCCGTCGCC AACACGGCAT CATCGCCGAA


 


51
ACGGcGGCGC AATACCGCAG CCAGCATTTC CTTCACCGTC GTCTTGCCGC


 


101
CCGAACCGGT AATGCCGAAC ACAAACGGAT TCACATTTTC ACGCCACGCC


 


151
TTTGCCAGCG TTTGCAATGC GGCAAGCGTG TCATCGACTT TCAACGCGCC


 


201
ATCCATTGCA GCACAATCTT CGCGCGAAAC CACAACCGCC GCCGCACCAG


 


251
CAGCCAATAC GTCTTCAACA AAATCATGCG CGTCAAACCG CTCGCCCGCC


 


301
AATGCGAAAA ACACATCGCC CGCGCGGATG TCGCGGCTGT CGGTTACGAT


 


351
GCGCGACACG GGTTTGCTTT CAGACGGCAT CGGAAGCTTG AGGGCTTGGC


 


401
AGATGAAATT TAGGTCCAGT GGTTTCATAT TTACTTTCGT TAATATTCGG


 


451
GCGGCGGACA CATCGGTAGC GGCTGATTTT TTTATCGCCT GTTTTGCTGT


 


501
GGTAAAACAC AGATTATTTT CCCATTCTCA TTCGGsATTT TTTCTGTACG


 


551
TATCATTTTT TAGACGTATT TTTAGTCGAT TTGCCTTTTC CCGCATACCA


 


601
CGGCGCGGGG TCGTCGGGCA GTCCGTCGAT AAAGGCAAGG TTATTGCCTT


 


651
CGCCCTGCAC ATCGGGAACA TTCCCCCAAA AATCATAGCC GTCATCGGGC


 


701
AACTCGTCGG TTTCGATACC CGTCCAACTG CCGAATCCGC GTAA






This corresponds to the amino acid sequence <SEQ ID 256; ORF 082>:










m082.pep




1
MXLLKLPAVA NTASSPKRRR NTAASISFTV VLPPEPVMPN TNGFTFSRHA


 


51
FASVCNAASV SSTFNAPSIA AQSSRETTTA AAPAANTSST KSCASNRSPA


 


101
NAKNTSPARM SRLSVTMRDT GLLSDGIGSL RAWQMKFRSS GFIFTFVNIR


 


151
AADTSVAADF FIACFAVVKH RLFSHSHSXF FLYVSFFRRI FSRFAFSRIP


 


201
RRGVVGQSVD KGKVIAFALH IGNIPPKIIA VIGQLVGFDT RPTAESA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 082 shows 92.7% identity over a 247 aa overlap with a predicted ORF (ORF 082.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 257>:










a082.seq




1
ATGTGGTTGT TGAAGTTGCC TGCCGTCGCC AAAACGGCAT TATCGCCGAA


 


51
ACGGCGGCGC AATACCGCAG CCAACATTTC CTTCACCGTC GTCTTGCCGC


 


101
CCGAGCCGGT AATACCGAAC ACAAACGGGT TCACATTCTC GCGCCACGCC


 


151
TTCGCCAACA TTTGCAACGC GGTAAGCGTG TCATCGACTT TCAACGCGCC


 


201
ATCCATTGCA ACGCAATCTT CGCGCGAAAC CACAACCGCC GCCGCACCCG


 


251
CAGCCAATAC GTCTTCAACA AAATCATGCG CATCAAACCG CCCGCCCGCC


 


301
AATGCGAAAA ACACATCGCC CGCGCGGATG TCGCGGCTGT CGGTTACGAT


 


351
GCGCGACACG GGTTTGCTTT CAGACGGCAT CGGAAGCTTG AGGGCTTGGC


 


401
AGATGAAATT TAGGTCCAGT GGTTTCATAT TTACTTTCGT TAATATTCGG


 


451
GCGGCGGACA CATCGGTAGC GGCTGATTTT TTTATCGCCT GTTTTGCTGT


 


501
GGTAAAACAC AGATTATTTT CCCATTCTCA TTCGGCATTT TTTCTGTACG


 


551
TATCATTTTT TAGACGTATT TTTAGTCGAT TTGCCTTTTC CCGCATACCA


 


601
CGGCGCGGGG TCGTCGGGCA GTCCGTCGAT AAAGGCAAGG TTATTGCCTT


 


651
CGCCCTGCAC ATCGGGAACA TTCCCCCAAA AATCATAGCC GTCATCGGGC


 


701
AACTCGTCGG TTTCGATACC CGTCCAACTG CCGAATCCGC GTAA






This corresponds to the amino acid sequence <SEQ ID 258; ORF 082.a>:










a082.pep




1
MWLLKLPAVA KTALSPKRRR NTAANISFTV VLPPEPVIPN TNGFTFSRHA


 


51
FANICNAVSV SSTFNAPSIA TQSSRETTTA AAPAANTSST KSCASNRPPA


 


101
NAKNTSPARM SRLSVTMRDT GLLSDGIGSL RAWQMKFRSS GFIFTFVNIR


 


151
AADTSVAADF FIACFAVVKH RLFSHSHSAF FLYVSFFRRI FSRFAFSRIP


 


201
RRGVVGQSVD KGKVIAFALH IGNIPPKIIA VIGQLVGFDT RPTAESA*






m082/a082 95.5% identity over a 247 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 259>:










g084.seq




1
ATGAAacaAT CCGcccgaat aAAAAATATG GATCAGACAT TAAAAAATAc



 


51
attgggcatt tGCGCGcttt tagcctTTTG TTTTggcgcG gccaTCGCAT


 


101
CAGGTTATCA CTTGGAATAT GAATACGGCT ACCGTTATTC TGCCGTGGGC


 


151
GCTTTGGCTT CGGTTGTATT TTTATTATTA TTGGCACGCG GCTTCCCGCG


 


201
CGTTTCTTCA GTTGTTTTAC TGATTTACGT CGGCACAACC GCCCTATATT


 


251
TGCCGGTCGG CTGGCTGTAT GGTGCGCCTT CTTATCAGAT AGTCGGTTCG


 


301
ATATTGGAAA GCAATCCTGC CGAGGCGCGT GAATTTGTCG GCAATCTTCC


 


351
CGGGTCGCTT TATTTTGTGC AGGCATTATT TTTCATTTTT GGCTTGACAG


 


401
TTTGGAAATA TTGTGTATCT GTGGGGGTAT TTGCTGACGT AAAAAACTAT


 


451
AAACGTCGCA GCAAAATATG GCTGACCATA TTATTGACTT TGATTTTGTC


 


501
CTGCGCGGTG ATGGAGAAAA TCGccggcga taaAGATTGG CGAGaacctg


 


551
atgccggcct gttgttgaat ATTTTcgacc tgtattaCga cttggctttc


 


601
cgcgccggca cAATATGCCG CCAAGCGCGC CCAcattttg gaagCagcaa


 


651
aaaaagcgtC AACATGGCAt atccgccaac ttgcgcccaa gTAtaa






This corresponds to the amino acid sequence <SEQ ID 260; ORF 084.ng>:










g084.pep




1
MKQSARIKNM DQTLKNTLGI CALLAFCFGA AIASGYHLEY EYGYRYSAVG



 


51
ALASVVFLLL LARGFPRVSS VVLLIYVGTT ALYLPVGWLY GAPSYQIVGS


 


101
ILESNPAEAR EFVGNLPGSL YFVQALFFIF GLTVWKYCVS VGVFADVKNY


 


151
KRRSKIWLTI LLTLILSCAV MEKIAGDKDW REPDAGLLLN IFDLYYDLAF


 


201
RAGTICRQAR PHFGSSKKSV NMAYPPTCAQ V*






The following partial DNA sequence wag identified in N. meningitidis <SEQ ID 261>:










m084.seq




1
ATGAAACAAT CCGCCcGAAT AAAa.ATATG AATCAGACAT TACTTTATAC



 


51
ATTGGGCATT TGCGCGCTTT TAACCTTTnn nnnnnnnnnn nnnnnnnnnn


 


101
nnnnnTATCA CCCnGAATAT GAATACGGCT ACCGTTATTC TGCCGTGGGT


 


151
GCTTTGGCTT CGGTTGTATT TTTATTATTA TTGGCACGCG GTTTCCCGCG


 


201
CGTTTCTTCA GTTGTTTTAC TGATTTACGT CGGCACAACC GCCCTATATT


 


251
TGCCGGTCGG CTGGCTGTAT GGTGCGCCGT CTTATCAGAT AGTCGGTTCG


 


301
ATATTGGAAA GCAATCCTGC CGAGGCGCGT GAATTTGTCG GCAATCTTCC


 


351
CGGGTCGCTT TATTTTGTGC AGGCATTATT TTTCATTTTT GGCTTGACAG


 


401
TTTGGAAATA TTGTGTATCG GGGGGGGTAT TTGCTGACGT AAAAAACTAT


 


451
AAACGCCGCA GCAAAATATG GCTGACTATA TTATTGACTT TGATTTTGTC


 


501
CTGCGCGGTG ATGGATAAAA TCGCCAGCGA TAAAGATTTG CGAGAACCTG


 


551
ATGCCGGCCT GTTGTTGAAT ATTTTCGACC TGTATTACGA TTTGGCT.TC


 


601
CGCGCCGGCA CAATATGCCG CCAAGCGCGC CCACATTTTG GAAGCAGCAA


 


651
AAAAAGCGTC AACATGGCAT ATCCGTCATG TTGCGCCCAA GTATAA






This corresponds to the amino acid sequence <SEQ ID 262; ORF 084>:










m084.pep




1
MKQSARIKXM NQTLLYTLGI CALLTFXXXX XXXXXYHPEY EYGYRYSAVG



 


51
ALASVVFLLL LARGFPRVSS VVLLIYVGTT ALYLPVGWLY GAPSYQIVGS


 


101
ILESNPAEAR EFVGNLPGSL YFVQALFFIF GLTVWKYCVS GGVFADVKNY


 


151
KRRSKIWLTI LLTLILSCAV MDKIASDKDL REPDAGLLLN IFDLYYDLAX


 


201
RAGTICRQAR PHFGSSKKSV NMAYPSCCAQ V*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 084 shows 90.5% identity over a 231 aa overlap with a predicted ORF (ORF 084.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 263>:










a084.seq




1
ATGAAACAAT CCGCCCGAAT AAAAAATATG GATCAGACAT TAAAAAATAC



 


51
ATTGGGCATT TGCGCGCTTT TAGCCTTTTG TTTTGGCGCG GCCATCGCAT


 


101
CAGGTTATCA CTTGGAATAT GAATACGGCT ACCGTTATTC TGCCGTGGGT


 


151
GCTTTGGCTT CGGTTGTATT TTTATTATTA TTGGCACGCG GTTTCCCGCG


 


201
CGTTTCTTCA GTTGTTTTAC TGATTTACGT CGGCACAACC GCCCTATATT


 


251
TGCCGGTCGG CTGGCTGTAT GGTGCGCCGT CTTATCAGAT AGTCGGTTCG


 


301
ATATTGGAAA GCAATCCTGC CGAGGCGCGT GAATTTGTCG GCAATCTTCC


 


351
CGGGTCGCTT TATTTTGTGC AGGCATTATT TTTCATTTTT GGCTTGACAG


 


401
TTTGGAGATA TTGTGTATCG GGGGGGGTAT TTGCTGACGT AAAAAACTAT


 


451
AAACGCCGCA GCAAAATATG GCTGACTATA TTATTGACTT TGATTTTGTC


 


501
CTGCGCGGTG ATGGATAAAA TCGCCAGCGA TAAAGATTTG CGAGAACCTG


 


551
ATGCCGGCCT GTTGTTGAAT ATTTTCGACC TGTATTACGA TTTGGCTTCC


 


601
.GCGCCGGCA CAATATGCCG CCAAGCGCGC CCACATTTTG GAAGCAGCAA


 


651
AAAAAGCGTC AACATGGCAT ATCCGTCATG TTGCGCCCAA GTATAA






This corresponds to the amino acid sequence <SEQ ID 264; ORF 084.a>:










a084.pep




1
MKQSARIKNM DQTLKNTLGI CALLAFCFGA AIASGYHLEY EYGYRYSAVG



 


51
ALASVVFLLL LARGFPRVSS VVLLIYVGTT ALYLPVGWLY GAPSYQIVGS


 


101
ILESNPAEAR EFVGNLPGSL YFVQALFFIF GLTVWRYCVS GGVFADVKNY


 


151
KRRSKIWLTI LLTLILSCAV MDKIASDKDL REPDAGLLLN IFDLYYDLAS


 


201
XAGTICRQAR PHFGSSKKSV NMAYPSCCAQ V*






m084/a084 92.2% identity over a 231 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 265>:










g085.seq




1
ATGGGCAAAG GGCAGGACTT CACGCCCCTG CGCGACGCGT TGAAAGATAA



 


51
GGCAAAAGGC GTGTTCCTGA TCGGCGTCGA TGCGCCGCAA ATCCGCCGCG


 


101
ATTTGGACGG CTGCGGCTTG AACCTGACCG ACTGCGTCAC TTTGGAAGAG


 


151
GCGGTTCAGA CGGCATACGC CCAAGCCGAA GCGGGCGATA TTGTCTTGCT


 


201
CAGCCCCGCC TGCGCGAGTT TCGATATGTT TAAAGGCTAC GCGCACCGTT


 


251
CGGAAGTGTT tatCGAAGCG TTTAAGGCTT TGTGA






This corresponds to the amino acid sequence <SEQ ID 266; ORF 085.ng>:










g085.pep




1
MGKGQDFTPL RDALKDKAKG VFLIGVDAPQ IRRDLDGCGL NLTDCVTLEE



 


51
AVQTAYAQAE AGDIVLLSPA CASFDMFKGY AHRSEVFIEA FKAL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 267>:










m085.seq




1
ATGGGTAAAG GGCAGGACTT CACGCCCCTG CGCGATGCAC TGGTAGGCAA



 


51
GGCAAAAGGC GTGTTCTTGA TTGGTGTCGA TGCGCCGCAA ATCCGCCGCG


 


101
ATTTGGACGG CTGCGGCTTG AATATGACCG ACTGCGCCAC TTTGGGAGAA


 


151
GCCGTTCAGA CGGCATATGC CCAAGCCGAA GCAGGCGATA TTGTGTTGCT


 


201
CAGCCCCGCC TGCGCGAGCT TTGATATGTT CAAAGGCTAC GCGCACCGTT


 


251
CGGAAGTGTT TATCGAAGCG TTTAAGGCTT TGTGA






This corresponds to the amino acid sequence <SEQ ID 268; ORF 085>:










m085.pep




1
MGKGQDFTPL RDALVGKAKG VFLIGVDAPQ IRRDLDGCGL NMTDCATLGE



 


51
AVQTAYAQAE AGDIVLLSPA CASFDMFKGY AHRSEVFIEA FKAL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 085 shows 94.7% identity over a 94 aa overlap with a predicted ORF (ORF 085.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 269>:










a085.seq




1
ATGGGCAAAG GGCAGGACTT CACGCCCCTG CGCGACGCGC TTGCCGGCAA



 


51
GGCAAAAGGC GTGTTCCTGA TCGGTGTCGA TGCGCCGCAA ATCCGCCGCG


 


101
ATTTGGACGG CTGCGATCTG AATATGACCG ACTGCGCCAC TTTGGAAGAA


 


151
GCGGTTCAGA AGGCATATGC CCAAGCCGAA GCGGGCGATA TCGTGCTGCT


 


201
CAGCCCCGCC TGCGCGAGTT TCGATATGTT TAAAGGCTAC GCGCACCGTT


 


251
CGGAAGTGTT TATCGGGGCG TTTAAGGCTT TGTGA






This corresponds to the amino acid sequence <SEQ ID 270; ORF 085.a>:










a085.pep




1
MGKGQDFTPL RDALAGKAKG VFLIGVDAPQ IRRDLDGCDL NMTDCATLEE



 


51
AVQKAYAQAE AGDIVLLSPA CASFDMFKGY AHRSEVFIGA FKAL*






m085/a085 94.7% identity over a 94 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 271>:










g086.seq




1
ATGGTGGTGC TGATGACGGC GTTCGGCCTG CTGATGATTT ATTCGGCTTC



 


51
TGTGTATTTG GCATCGAAGG AAGGCGGCGA TCAGTTTTTC TATTTGACCA


 


101
GGCAGGCGGG GTTCGTCGTT GCCGGCCTTA TAGCGAGCGG TTTTTTATGG


 


151
TTTCTTTGCA GGATGAGGAC ATGGCGGCGG CTTGTGCCGT GGATTTTTGC


 


201
CTTATCCGGC CTGTTGCTGG TAGCCGTATT GATTGCCGGG CGCGAAATCA


 


251
ATGGCGCGAC CCGTTGGATA CCTTTGGGTC CGTTGAATTT CCAGCCGACC


 


301
GAGCTGTTCA AGCTGGCAGT CATCCTTTAT TTGGCAAGCC TGTTCACGCG


 


351
CCGTGAAGAA GTGTTGCGCA GCATGGAAAG TTTGGGTTGG CAGTCGATTT


 


401
GGCGGGGGAC GGCCAACCTG ATTATGTCCG CCACCAATCC GCAGGCACGT


 


451
CGTGAAACAT TAGAAATGTA CGgcCGTTTC CGGGCGATCA TCCTGCCGAT


 


501
TATGCTGGTG GCGTTCGGTT TGGTGCTGAT AATGGTACAG CCGGATTTCG


 


551
GTTCGTTTGT CGTCATTACC GTCATTACCG TTGGAATGCT GTTTCTGGCA


 


601
GGATTGCCGT GGAAATATTT TTTTGTCCTG GTAGGCAGCG TCTTGGGTGG


 


651
GATGGTGCTG ATGATTACCG CCGCTCCCTA CCGTGTGCAG CGGGTAGTGG


 


701
CATTTTTGGA CCCGTGGAAA GACCCGCAGG GTGCCGGCTA CCAGCTTACC


 


751
CACTCTCTGA TGGCAATCGG GCGCGGAGAG TGGTTCGGTA TGGGTTTGGG


 


801
TGCGAGTTTG AGCAAACGCG GCTTTCTGCC GGAAGCGCAT ACCGATTTTA


 


851
TTTTTGCCAT CATCGCTGAA GAATTCGGCT TCTTCGGGAT GTGCGTGCTG


 


901
ATATTCTGTT ACGGCTGGCT GGTGGTGCGG GCGTTTTCCA TCGGCAAGCA


 


951
GTCGCGCGAT TTGGGtttgA CTTTCAACGC CTATATCGCT TCGGGTATCG


 


1001
GCATTTGGAT CGGTATCCAA AGTTTCTTCA ATATCGGTGT GAACATCGGT


 


1051
GCTTTGCCGA CCAAAGGTCT GACGctgCcg tTGATGTCCT ATGGcggTTC


 


1101
GTCAGTCTTT TTCATGCTGA TCAGCATGAT GCTGCTGTTG CGTATCGATT


 


1151
ATGAAAACCG CCAGAAAATG CGCGGTTACC GGGTGGAGTA AA






This corresponds to the amino acid sequence <SEQ ID 272; ORF 086.ng>:










g086.pep




1
MVVLMTAFGL LMIYSASVYL ASKEGGDQFF YLTRQAGFVV AGLIASGFLW



 


51
FLCRMRTWRR LVPWIFALSG LLLVAVLIAG REINGATRWI PLGPLNFQPT


 


101
ELFKLAVILY LASLFTRREE VLRSMESLGW QSIWRGTANL IMSATNPQAR


 


151
RETLEMYGRF RAIILPIMLV AFGLVLIMVQ PDFGSFVVIT VITVGMLFLA


 


201
GLPWKYFFVL VGSVLGGMVL MITAAPYRVQ RVVAFLDPWK DPQGAGYQLT


 


251
HSLMAIGRGE WFGMGLGASL SKRGFLPEAH TDFIFAIIAE EFGFFGMCVL


 


301
IFCYGWLVVR AFSIGKQSRD LGLTFNAYIA SGIGIWIGIQ SFFNIGVNIG


 


351
ALPTKGLTLP LMSYGGSSVF FMLISMMLLL RIDYENRQKM RGYRVE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 273>:










m086.seq




1
ATGGTGGTGC TGATGACGGC GTTCAGCCTG CTGATGATTT ATTCGGCTTC



 


51
TGTGTATTTG GCATCAAAAG AAGGCGGCGA TCAGTTTTTC TATTTGACCA


 


101
GACAGGCGGG GTTCGTCGTT GCCGGCTTGA TAGCGAGCGG TTTGTTATGG


 


151
TTTCTTTGCA GGATGAGGAC ATGGCGGCGG CTTGTGCCGT GGATTTTTGC


 


201
CCTATCCGGC CTGTTGCTGG TAGTCGTATT GATTGCCGGG CGCGAAATCA


 


251
ATGGCGCGAC CCGTTGGATA CCTTTGGGTC CGTTGAATTT CCAGCCGACc


 


301
GAGCTGTTCA AGCtGGCGGT CATCCTTTAT TTGGCAAGCC TGTTCACGCG


 


351
CCGTGAAGAA GTGTTGcGCA GCATGGAAAG TTTGGGTTGG CAGTCGATTT


 


401
GGCGGGGGAC GGCCAATCTG ATCATGTCCG CCACCAATCC GCAGrCACGT


 


451
CGTGAaACAT TAGAAATGTA CGGCCGTwTC CGGGCGATCA TCCTGCCGAT


 


501
TATGCTGGTG GCGTTCGGTT TGGTGCTGAT AATGGTACAG CCGGATTTCG


 


551
GTTCGTTTGT CGTCATTACC GTCATTGCCG TTGGAATGCT GTTTTTGGCA


 


601
GGATTGCCGT GGAAATATTT TTTCGTCCTG GTAGGCAGCG TCTTGGGCGG


 


651
GATGGTGCTG ATGATTACCG CCGCTCCCTA CCGTGTGCAG CGGGTAGTGG


 


701
CATTTTTGGA CCCGTGGAAA GACCCGCAGG GTGCCGGCTA CCAGCTTACC


 


751
CACTCTCTGA TGGCAATCGG GCGCGGAGAG TGGTTCGGTA TGGGTTTGGG


 


801
TGCGAGTTTG AGCAAACGCG GCTTTCTGCC GGAAGCGCAT ACCGATTTTA


 


851
TTTTTGCCAT CATCGCCGAA GAATTCGGTT TCTTCGGTAT GTGCGTGCTG


 


901
ATATTCTGTT ACGGCTGGCT GGTGGTGCGG GCGTTTTCCA TCGGCAAGCA


 


951
GTCGCGCGAT TTGGGTTTGA CTTTCAACGC CTATATCGCT TCGGGTATCG


 


1001
GCATTTGGAT CGGkrTCCAA AGTTTCTTCA ATATCGGTGT GAACATCGGT


 


1051
GCTTTGCCGA mCAAAgGyCT GACGCyGCCG Tg.AtGTCCw ATGGCGGTTC


 


1101
GTCAGTCTTT TTCATGCTGA TCAGCATGAT GCTGCTGTkG CGTATAGATT


 


1151
ATGAAAACCG CCGGAAAATG CGCGGTTATC GGGTGGAGTA A






This corresponds to the amino acid sequence <SEQ ID 274; ORF 086>:










m086.pep




1
MVVLMTAFSL LMIYSASVYL ASKEGGDQFF YLTRQAGFVV AGLIASGLLW


 


51
FLCRMRTWRR LVPWIFALSG LLLVVVLIAG REINGATRWI PLGPLNFQPT


 


101
ELFKLAVILY LASLFTRREE VLRSMESLGW QSIWRGTANL IMSATNPQXR


 


151
RETLEMYGRX RAIILPIMLV AFGLVLIMVQ PDFGSFVVIT VIAVGMLFLA


 


201
GLPWKYFFVL VGSVLGGMVL MITAAPYRVQ RVVAFLDPWK DPQGAGYQLT


 


251
HSLMAIGRGE WFGMGLGASL SKRGFLPEAH TDFIFAIIAE EFGFFGMCVL


 


301
IFCYGWLVVR AFSIGKQSRD LGLTFNAYIA SGIGIWIGXQ SFFNIGVNIG


 


351
ALPXKGLTXP XMSXGGSSVF FMLISMMLLX RIDYENRRKM RGYRVE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 086 shows 96.7% identity over a 396 aa overlap with a predicted ORF (ORF 086.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 275>:










a086.seq




1
ATGGTGGTGC TGATGACGGC GTTCAGCCTG CTGATGATTT ATTCGGCTTC


 


51
TGTGTATTTG GCATCAAAAG AAGGCGGCGA TCAGTTTTTC TATTTGACCA


 


101
GACAGGCGGG GTTCGTCGTT GCCGGCTTGA TAGCGAGCGG TTTGTTATGG


 


151
TTTCTTTGCA GGATGAGGAC ATGGCGGCGG CTTGTGCCGT GGATTTTTGC


 


201
CCTATCCGGC CTGTTGCTGG TAGTCGTATT GATTGCCGGG CGCGAAATCA


 


251
ATGGCGCGAC CCGTTGGATA CCTTTGGGTC CGTTGAATTT CCAGCCGACC


 


301
GAGCTGTTCA AGCTGGCGGT CATCCTTTAT TTGGCAAGCC TGTTCACGCG


 


351
CCGTGAAGAA GTGTTGCGCA GCATGGAAAG TTTGGGTTGG CAGTCGATTT


 


401
GGCGGGGGAC GGCCAATCTG ATCATGTCCG CCACCAATCC GCAGGCACGT


 


451
CGTGAAACAT TAGAAATGTA CGGCCGTTTC CGGGCGATCA TCCTGCCGAT


 


501
TATGCTGGTG GCGTTCGGTT TGGTGCTGAT AATGGTACAG CCGGATTTCG


 


551
GTTCGTTTGT CGTCATTACC GTCATTGCCG TTGGAATGCT GTTTTTGGCA


 


601
GGATTGCCGT GGAAATATTT TTTCGTCCTG GTAGGCAGCG TCTTGGGCGG


 


651
GATGGTGCTG ATGATTACCG CCGCTCCCTA CCGTGTGCAG CGGGTAGTGG


 


701
CATTTTTGGA CCCGTGGAAA GACCCGCAGG GTGCCGGCTA CCAGCTTACC


 


751
CACTCTCTGA TGGCAATCGG GCGCGGAGAG TGGTTCGGTA TGGGTTTGGG


 


801
TGCGAGTTTG AGCAAACGCG GCTTTCTGCC GGAAGCGCAT ACCGATTTTA


 


851
TTTTTGCCAT CATCGCCGAA GAATTCGGTT TCTTCGGTAT GTGCGTGCTG


 


901
ATATTCTGTT ACGGCTGGCT GGTGGTGCGG GCGTTTTCCA TCGGCAAGCA


 


951
GTCGCGCGAT TTGGGTTTGA CTTTCAACGC CTATATCGCT TCGGGTATCG


 


1001
GCATTTGGAT CGGTATCCAA AGTTTCTTCA ATATCGGTGT GAACATCGGT


 


1051
GCTTTGCCGA CCAAAGGTCT GACGCTGCCG TTGATGTCCT ATGGCGGTTC


 


1101
GTCAGTCTTT TTCATGCTGA TCAGCATGAT GCTGCTGTTG CGTATAGATT


 


1151
ATGAAAACCG CCGGAAAATG CGCGGTTACC GGGTGGAGTA A






This corresponds to the amino acid sequence <SEQ ID 276; ORF 086.a>:










a086.pep




1
MVVLMTAFSL LMIYSASVYL ASKEGGDQFF YLTRQAGFVV AGLIASGLLW


 


51
FLCRMRTWRR LVPWIFALSG LLLVVVLIAG REINGATRWI PLGPLNFQPT


 


101
ELFKLAVILY LASLFTRREE VLRSMESLGW QSIWRGTANL IMSATNPQAR


 


151
RETLEMYGRF RAIILPIMLV AFGLVLIMVQ PDFGSFVVIT VIAVGMLFLA


 


201
GLPWKYFFVL VGSVLGGMVL MITAAPYRVQ RVVAFLDPWK DPQGAGYQLT


 


251
HSLMAIGRGE WFGMGLGASL SKRGFLPEAH TDFIFAIIAE EFGFFGMCVL


 


301
IFCYGWLVVR AFSIGKQSRD LGLTFNAYIA SGIGIWIGIQ SFFNIGVNIG


 


351
ALPTKGLTLP LMSYGGSSVF FMLISMMLLL RIDYENRRKM RGYRVE*






m086/a086 98.0% identity over a 396 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 277>:










g087.seq




1
ATGGGCGGTA AAACCTTTAT GCTGATGGCG GGCGGAACGG GCGGACACAT


 


51
TTTCCCAGCT CTGGCTGTGG CGGATTCATT GCGCGTGCGC GGTCATCATG


 


101
TAATTTGGCT GGGCAGCAAG GATTCGATGG AAGAGCGCAT CGTGCCGCAA


 


151
TACGGCATAC GCTTGGAAAC GCTGGCGATT AAAGGAATAC GCGGCAACGG


 


201
CATCAAACGC AAGCTGATGC TTCCGTTTAC TCTGTACAAA ACCGTCCGCG


 


251
AAGCGCAGCG GATTATCCGC AAACACCGTG TCGAGTGCGT CATCGGCTTC


 


301
GGCGGTTTTG TTACCTTTCC CGGCGGTCTG GCGGCGAAAC TCTTGGGCGT


 


351
GCCGATTGTG ATTCACGAGC AAAACGCCGT GGCAGGCTTG TCCAACCGCC


 


401
AccTGTCGCg ctGGGCGAAA CGGGTGTTGT ACGCTTTTCC GAAAGCGTTC


 


451
AGCCACGAAG GCGGTTTGGT CGGCAACCCC GTCCGCGCCG ATATTAGCAA


 


501
CCTGCCCGTG CCTGCCGAAC GCTTCCAAGG GCGCGAAGGC CGTCTGAAAA


 


551
TTTTGGTGGT CGGCGGCAGT TTGGGTGCGG ACGTTTTGAA CAAAACCGTA


 


601
CCGCAGGCGT TGGCACTGCT GCCTGAAGAG GTGCGCCCGC AGATGTACCA


 


651
CCAGTCGGGG CGTAACAAGC TGGGCAATCT TCAGGCGGAT TATGACGCGT


 


701
TGGGCGTGAA AGCGGAATGC GTGGAATTTA TTACCGACAT GGTGTCCGCC


 


751
TACCGTGATG CCGATTTGGT GATTTGCCGT GCCGGCGCGC TGACGATTGC


 


801
CGAGTTGACG GCGGCGGGGC TGGGCGCGTT GTTAGTGCCG TATCCTCACG


 


851
CCGTTGATGA CCATCAAACC GCCAACGCGC GTTTCATGGT GCAGGCAGAA


 


901
GCGGGGCTGC TGTTGCCGCA AACCCAGTTG ACGGCGGAAA AACTCGCCGA


 


951
AATCCTCGGC AGCCTCAACC GCGAAAAATG CCTCAAATGG GCGGAAAACG


 


1001
CCCGTACGTT GGCATTGCCG CACAGCGCGG ATGACGTTGC CGAAGCCGCG


 


1051
ATTGCGTGTG CGGCGTAAA






This corresponds to the amino acid sequence <SEQ ID 278; ORF 087.ng>:










g087.pep




1
MGGKTFMLMA GGTGGHIFPA LAVADSLRVR GHHVIWLGSK DSMEERIVPQ


 


51
YGIRLETLAI KGIRGNGIKR KLMLPFTLYK TVREAQRIIR KHRVECVIGF


 


101
GGFVTFPGGL AAKLLGVPIV IHEQNAVAGL SNRHLSRWAK RVLYAFPKAF


 


151
SHEGGLVGNP VRADISNLPV PAERFQGREG RLKILVVGGS LGADVLNKTV


 


201
PQALALLPEE VRPQMYHQSG RNKLGNLQAD YDALGVKAEC VEFITDMVSA


 


251
YRDADLVICR AGALTIAELT AAGLGALLVP YPHAVDDHQT ANARFMVQAE


 


301
AGLLLPQTQL TAEKLAEILG SLNREKCLKW AENARTLALP HSADDVAEAA


 


351
IACAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 279>:










m087.seq




1
ATGGGCGGTA AAACCTTTAT GCTGAwkkCG GGCGGAACGG GCGGACATAT


 


51
TTTCCCCGCG CTGGCGGTGG CGGATTCATT GCGCGCGCGC GGCCATCATG


 


101
TGATTTGGCT GGGCAGCAAG GATTCGATGG AAGAGCGTAT CGTGCCGCAA


 


151
TACGGCATAC GCTTGGAAAC GCTGGCGATT AAAGGCGTGC GCGGCAACGG


 


201
CATCAAACGC AAACTGATGC TGCCGGTTAC TTTGTATCAA ACCGTCCGCG


 


251
AAGCGCAGCG GATTATCCGC AAACACCGTG TCGAGTGCGT CATCGGCTTC


 


301
GGCGGCTTCG TTACCTTCCC CGGCGGTTTG GCGGCGAAGC TATTArGCGT


 


351
GCCGATTGTG ATTCACGAGC AAAACGCCGT GGCAGGTTTG TCCAACCGCC


 


401
ACCTGTCGCG CTGGGCGAAG CGGGTGTTGT ACGCTTTTCC GAAAGCGTTC


 


451
AGCCACGAAG GCGGCTTGGT CGGCAACCCC GTCCGCGCCG ATATTAGCAA


 


501
CCTGCCCGTG CCTGCCGAAC GCTTCCAAGG GCGTGAAGGC CGTCTGAAAA


 


551
TTTTGGTGGT CGGCGGCAGT TTGGGCGCGG ACGTTTTGAA CAAAACCGTA


 


601
CCGCATGCAT TGGCTTTGCT GCCCGACAAT GCGCGTCCGC ATATGTACCA


 


651
CCAATCGGGA CGGGGCAAGC TGGGCATCTT GCAGGCGnnn nnnnnnnnnn


 


701
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


751
nnnGCGGGAT TGGGTGCGTT GTTAGTGCCG TATCCTCACG CGGTTGACGA


 


801
TCACCAAACC GCCAACGCGC GTTTTATGGT GCAGGCGGAG GCGGGATTGC


 


851
TGTTGCCGCA AACCCAGTTG ACGGCGGAAA AACTCGCCGA GATTCTCGGC


 


901
GGCTTAAACC GCGAAAAATG CCTCAAATGG GCAGAAAACG CCCGTACGTT


 


951
GGCACTGCCG CACAGTGCGG ACGACGTGGC GGAAGCCGCG ATTGCGTGTG


 


1001
CGGCGTAA






This corresponds to the amino acid sequence <SEQ ID 280; ORF 087>:










m087.pep




1
MGGKTFMLXX GGTGGHIFPA LAVADSLRAR GHHVIWLGSK DSMEERIVPQ


 


51
YGIRLETLAI KGVRGNGIKR KLMLPVTLYQ TVREAQRIIR KHRVECVIGF


 


101
GGFVTFPGGL AAKLLXVPIV IHEQNAVAGL SNRHLSRWAK RVLYAFPKAF


 


151
SHEGGLVGNP VRADISNLPV PAERFQGREG RLKILVVGGS LGADVLNKTV


 


201
PHALALLPDN ARPHMYHQSG RGKLGILQAX XXXXXXXXXX XXXXXXXXXX


 


251
XAGLGALLVP YPHAVDDHQT ANARFMVQAE AGLLLPQTQL TAEKLAEILG


 


301
GLNREKCLKW AENARTLALP HSADDVAEAA IACAA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 087 shows 83.9% identity over a 355 aa overlap with a predicted ORF (ORF 087.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 281>:










a087.seq




1
ATGGGCGGTA AAACCTTTAT GCTGATGGCG GGCGGAACGG GCGGACATAT


 


51
TTTCCCCGCG CTGGCGGTGG CGGATTCATT GCGCGCGCGC GGCCATCATG


 


101
TAATTTGGCT GGGCAGCAAG GATTCGATGG AAGAGCGCAT CGTGCCGCAA


 


151
TACGACATCC TGCTCGAAAC GCTGGCGATT AAAGGCGTGC GCGGCAACGG


 


201
CATCAAACGC AAGCTGATGC TGCCGTTTAC TTTGTATCAA ACTGTCCGCG


 


251
AAGCGCAGCA GATTATCCGC AAACACCGTG TCGAGTGCGT CATCGGCTTC


 


301
GGCGGCTTCG TTACCTTTCC CGGCGGTTTG GCGGCGAAGT TATTAGGCGT


 


351
GCCGATTGTG ATTCACGAGC AAAACGCCGT GGCAGGTTTG TCCAACCGCC


 


401
ACCTGTCGCG CTGGGCGAAG CGGGTGTTGT ACGCTTTTCC GAAAGCGTTC


 


451
AGCCACGAAG GCGGCTTGGT CGGCAACCCC GTCCGCGCCG ATATTAGCAA


 


501
CCTGCCCGTG CCTGCCGAAC GCTTCCAAGG GCGTGAAGGC CGTCTGAAAA


 


551
TTTTGGTGGT CGGCGGCAGT TTGGGCGCGG ACGTTTTGAA CAAAACCGTA


 


601
CCGCAGGCAT TGGCTTTGCT GCCCGACAAT GCGCGTCCGC AGATGTACCA


 


651
CCAATCGGGA CGGGGCAAGC TGGGCAGCTT GCAGGCGGAT TACGACGCGC


 


701
TGGGCGTGCA AGCGGAATGC GTGGAATTTA TTACCGATAT GGTGTCCGCC


 


751
TACCGCGATG CCGATTTGGT GATTTGCCGT GCCGGCGCGC TGACGATTGC


 


801
CGAGTTGACG GCGGCGGGAT TGGGTGCGTT GTTAGTGCCG TATCCTCACG


 


851
CCGTTGATGA CCATCAAACC GCCAACGCGC GTTTTATGGT GCAGGCGGAG


 


901
GCGGGATTGC TGTTGCCGCA AACCCAGTTG ACGGCGGAAA AACTCGCCGA


 


951
GATTCTCGGC GGCTTAAACC GCGAAAAATG CCTCAAATGG GCAGAAAACG


 


1001
CCCGTACGTT GGCACTGCCG CACAGTGCGG ACGACGTTGC CGAAGCCGCG


 


1051
ATTGCGTGTG CGGCGTAA






This corresponds to the amino acid sequence <SEQ ID 282; ORF 087.a>:










a087.pep




1
MGGKTFMLMA GGTGGHIFPA LAVADSLRAR GHHVIWLGSK DSMEERIVPQ


 


51
YDILLETLAI KGVRGNGIKR KLMLPFTLYQ TVREAQQIIR KHRVECVIGF


 


101
GGFVTFPGGL AAKLLGVPIV IHEQNAVAGL SNRHLSRWAK RVLYAFPKAF


 


151
SHEGGLVGNP VRADISNLPV PAERFQGREG RLKILVVGGS LGADVLNKTV


 


201
PQALALLPDN ARPQMYHQSG RGKLGSLQAD YDALGVQAEC VEFITDMVSA


 


251
YRDADLVICR AGALTIAELT AAGLGALLVP YPHAVDDHQT ANARFMVQAE


 


301
AGLLLPQTQL TAEKLAEILG GLNREKCLKW AENARTLALP HSADDVAEAA


 


351
IACAA*






m087/a087 85.4% identity over a 355 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 283>:










g088.seq




1
ATGTTTTTAT GGCTCGCACA TTTCAGCAAC TGGTTAACCG GTCTGAATAT


 


51
TTTTCAATAC ACCACATTCC GCGCCGTTAT GGCGGCGTTG ACCGCCTTGG


 


101
CGTTTTCCCT GATGTTCGGC CCGTGGACGA TACGCAGGCT GACCGCGCTC


 


151
AAATGCGGGC AGGCAGTGCG TACCGACGGC CCGCAAACCC ACCTCGTCAA


 


201
AAACGGCACG CCGACGATGG GCGGTTCGCT GATTCTGACC GCCATTACCG


 


251
TGTCCACCCT GTTGTGGGGC AACTGGGCGA ACCCGTATAT CTGGATTCTC


 


301
TTGGGCGTAC TGCTTGCCAC CGGTGCGCTC GGTTTTTACG ACGACTGGCG


 


351
CAAAGTCGTT TATAAAGACC CCAACGGCGT GTCCGCCAAA TTCAAAATGG


 


401
TGTGGCAGTC AAGCGTTGCC GTTatcgcCG GTttggcaTT GTTTTACctt


 


451
gCcgcCAATT CCGCCAACAA TATTTTGATT GTCCCGtttT TCAAACAAAT


 


501
CGCCCTGCCG CTGGGCGTGG TCGGCTTttt gGtgttgTCT TACCTGACCA


 


551
TCGTCGGCAC ATCCAACGCC GTCAACCTCA CcgaCGGCTT GGACGGCCTT


 


601
GCCGCcttcc cgttcgtcct cgttgccgcC GGGCTCGCCA ttttcgccTA


 


651
CGTCAGCGGA CACTACCAAT TTTCCCAATA CCTCCAGCTT CCCTATGTCG


 


701
CCGGCGCGAA CGAAGTCGCT ATATTCTGCA CCGCCATGTG CGGCGCGTGC


 


751
CTCGGATTTT TGTGGTTCAA CGCCTATCCC GCGCAAGTCT TTATGGGCGA


 


801
TGTCGGCGCG CTGGCATTGG GTGCCGCGCT CGGTaccGtt gCCGTcaTcg


 


851
tCCGCCAAGA ATTTGTcctc gtcattaTGG GCGGTCTGTT cgtcgtagaa


 


901
gccgtgTCCG TTATGCTTCa tgtcggCTGG TACAAGAAAA Ccaaaaaacg


 


951
CATCTTcCTg acgGcaccga ttcatcacca ttaCCaactt cgatgCTGGa


 


1001
aagaaacgca agtcgtcgtc CGTTtCTGGA TTAtTAccat cgtcgtggtt


 


1051
tTgataggtt tGagtacccT caAAattcgc ggaaactatg ccgTCCGAAC


 


1101
ACCTTTCAGA CGGCATTTGA ACGCGCAATA A






This corresponds to the amino acid sequence <SEQ ID 284; ORF 088.ng>:










g088.pep




1
MFLWLAHFSN WLTGLNIFQY TTFRAVMAAL TALAFSLMFG PWTIRRLTAL


 


51
KCGQAVRTDG PQTHLVKNGT PTMGGSLILT AITVSTLLWG NWANPYIWIL


 


101
LGVLLATGAL GFYDDWRKVV YKDPNGVSAK FKMVWQSSVA VIAGLALFYL


 


151
AANSANNILI VPFFKQIALP LGVVGFLVLS YLTIVGTSNA VNLTDGLDGL


 


201
AAFPFVLVAA GLAIFAYVSG HYQFSQYLQL PYVAGANEVA IFCTAMCGAC


 


251
LGFLWFNAYP AQVFMGDVGA LALGAALGTV AVIVRQEFVL VIMGGLFVVE


 


301
AVSVMLHVGW YKKTKKRIFL TAPIHHHYQL RCWKETQVVV RFWIITIVVV


 


351
LIGLSTLKIR GNYAVRTPFR RHLNAQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 285>:










m088.seq




1
ATGTTTTTAT GGCTCGCACA TTTCAGCAnC TGGTTAACCG GTCTGAATnn


 


51
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


101
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


151
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


201
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


251
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


301
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


351
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


401
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


451
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn


 


501
nnnnnnnnnn nnnGGCGTGG TCGGCTTTTT GGTGTTGTCT TACCTGACCA


 


551
TCGTCGGCAC ATCCAATGCC GTCAACCTCA CCGACGGCTT GGACGGCCTT


 


601
GCGACCTTCC CCGTCGTCCT CGTTGCCGCC GGCCTCGCCA TCTTCGCCTA


 


651
TGCCAGCGGC CACTCACAAT TTGCCCAATA CCTGCAATTA CCTTACGTTG


 


701
CCGGCGCAAA CGAAGTGGTG ATTTTCTGTA CCGCCATGTG CGGCGCGTGC


 


751
CTCGGTTTCT TGTGGTTTAA CGCCTATCCC GCGCAAGTCT TTATGGGCGA


 


801
TGTCGGTGCA TTGGCATTGG GTGCCGCGCT CGGTACCGTC GCCGTTATCG


 


851
TCCGCCAAGA GTTTGTCCTC GTCATTATGG GCGGATTATT TGTCGTAGAA


 


901
GCCGTATCCG TTATGCTTCA GGTTGGCTGG TATAAGAAAA CCAAAAAACG


 


951
CATCTTCCTG ATGGCGCCCA TCCATCACCA CTACGAACAA AAAGGCTGGA


 


1001
AAGAAACCCA AGTCGTCGTC CGCTTTTGGA TTATTACCAT CGTCTTGGTG


 


1051
TTGATCGGTT TGAGTACCCT CAAAATCCGC TGAACCTATG CCGTCTGAAC


 


1101
ATCTTTCAGA CGGCATTTGA ACGCGCAATA A


 


1
MFLWLAHFSN WLTGLNIFQY TTFRAVMAAL TALAFSLMFG PWTIRRLTAL


 


51
KCGQAVRTDG PQTHLVKNGT PTMGGSLILT AITVSTLLWG NWANPYIWIL


 


101
LGVLLATGAL GFYDDWRKVV YKDPNGVSAK FKMVWQSSVA VIAGLALFYL


 


151
AANSANNILI VPFFKQIALP LGVVGFLVLS YLTIVGTSNA VNLTDGLDGL


 


201
AAFPFVLVAA GLAIFAYVSG HYQFSQYLQL PYVAGANEVA IFCTAMCGAC


 


251
LGFLWFNAYP AQVFMGDVGA LALGAALGTV AVIVRQEFVL VIMGGLFVVE


 


301
AVSVMLHVGW YKKTKKRIFL TAPIHHHYQL RCWKETQVVV RFWIITIVVV


 


351
LIGLSTLKIR GNYAVRTPFR RHLNAQ*






This corresponds to the amino acid sequence <SEQ ID 286; ORF 088>:










m088.pep




1
MFLWLAHFSX WLTGLNXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX


 


51
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX


 


101
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX


 


151
XXXXXXXXXX XXXXXXXXXX XGVVGFLVLS YLTIVGTSNA VNLTDGLDGL


 


201
ATFPVVLVAA GLAIFAYASG HSQFAQYLQL PYVAGANEVV IFCTAMCGAC


 


251
LGFLWFNAYP AQVFMGDVGA LALGAALGTV AVIVRQEFVL VIMGGLFVVE


 


301
AVSVMLQVGW YKKTKKRIFL MAPIHHHYEQ KGWKETQVVV RFWIITIVLV


 


351
LIGLSTLKIR XTYAVXTSFR RHLNAQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 088 shows 91.7% identity over a 205 aa overlap with a predicted ORF (ORF 088.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 287>:










a088.seq




1
ATGTTTTTAT GGCTCGCACA TTTCAGCAAC TGGTTAACCG GTCTGAATAT


 


51
TTTTCAATAC ACCACATTCC GCGCCGTCAT GGCGGCGTTG ACCGCCTTGG


 


101
CGTTTTCCCT GATGTTCGGC CCGTGGACGA TACGCAGGCT GACCGCGCTC


 


151
AAATGCGGGC AGGCAGTGCG TACCGACGGT CCGCAAACCC ACCTCGTCAA


 


201
AAACGGCACG CCGACGATGG GCGGTTCGCT GATTCTGACC GCCATTACCG


 


251
TGTCCACCCT GTTGTGGGGC AACTGGGCAA ACCCGTATAT CTGGATTCTC


 


301
TTGGGCGTAT TGCTCGCCAC GGGCGCACTC GGTTTTTACG ACGACTGGCG


 


351
CAAAGTCGTC TATAAAGACC CCAACGGCGT GTCCGCCAAA TTCAAAATGG


 


401
TGTGGCAGTC AAGCGTTGCC ATTATCGCCG GTTTGGCATT GTTTTACCTT


 


451
GCCGCCAATT CCGCCAACAA TATTTTGATT GTCCCGTTCT TCAAACAAAT


 


501
CGCCCTGCCG CTGGGCGTGG TCGGCTTTTT GGTGTTGTCT TACCTGACCA


 


551
TCGTCGGCAC ATCCAATGCC GTCAACCTCA CCGACGGCTT GGACGGCCTT


 


601
GCGACCTTCC CCGTCGTCCT CGTTGCCGCC GGCCTCGCCA TCTTCGCCTA


 


651
TGCCAGCGGC CACTCACAAT TTGCCCAATA CCTGCAATTA CCTTACGTTG


 


701
CCGGCGCAAA CGAAGTGGTG ATTTTCTGTA CCGCCATGTG CGGCGCGTGC


 


751
CTCGGTTTCT TGTGGTTTAA CGCCTATCCC GCGCAAGTCT TTATGGGCGA


 


801
TGTCGGTGCA TTGGCATTGG GTGCCGCGCT CGGTACCGTC GCCGTCATCG


 


851
TCCGCCAAGA GTTTGTCCTC GTCATTATGG GCGGATTATT TGTCGTAGAA


 


901
GCCGTATCCG TTATGCTTCA GGTCGGCTGG TATAAGAAAA CCAAAAAACG


 


951
CATCTTCCTG ATGGCGCCCA TCCATCACCA CTACGAACAA AAAGGCTGGA


 


1001
AAGAAACCCA AGTCGTCGTC CGCTTTTGGA TTATTACCAT CGTCTTGGTG


 


1051
TTGATCGGTT TGAGTACCCT CAAAATCCGC TGAACCTATG CCGTCTGAAC


 


1101
ACCTTTCAGA CGGCATTTGA ACGCGCAATA A






This corresponds to the amino acid sequence <SEQ ID 288; ORF 088.a>:










a088.pep




1
MFLWLAHFSN WLTGLNIFQY TTFRAVMAAL TALAFSLMFG PWTIRRLTAL


 


51
KCGQAVRTDG PQTHLVKNGT PTMGGSLILT AITVSTLLWG NWANPYIWIL


 


101
LGVLLATGAL GFYDDWRKVV YKDPNGVSAK FKMVWQSSVA IIAGLALFYL


 


151
AANSANNILI VPFFKQIALP LGVVGFLVLS YLTIVGTSNA VNLTDGLDGL


 


201
ATFPVVLVAA GLAIFAYASG HSQFAQYLQL PYVAGANEVV IFCTAMCGAC


 


251
LGFLWFNAYP AQVFMGDVGA LALGAALGTV AVIVRQEFVL VIMGGLFVVE


 


301
AVSVMLQVGW YKKTKKRIFL MAPIHHHYEQ KGWKETQVVV RFWIITIVLV


 


351
LIGLSTLKIR *TYAV*TPFR RHLNAQ*






m088/a088 99.5% identity over a 205 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 289>:










g089.seq




1
ATGCCGCCCA AAATCACGAA GAGCGGGTTT TGCAAACCGG CAATCGCGGC



 


51
GGCGGTCGCG CCGACATTCG TGCCTTTGCT GTCGTCGATG AATACCACGC


 


101
CGTTTTTCTC GCCGATTTTT TCCACACGGT GCGGCAAGCC TTGGAAGGTT


 


151
TTGACGTGTT CCAGCAATGC TTCGCGCGGC AAACCGACGG CCTCGCACAA


 


201
AGCCACGGCA GCCATAACGT TGGCGGCGTT GTGCAAACCT TGCAGCGGGA


 


251
TGTCTTGCGT AGAAATCAAA TCTTCATTGC CTTGTTTTAA ACAGCCCGTC


 


301
CCGCGTTCCA ACCAAAAATC GGCTTCGTGT TCCAAGGAAA ACCGTTTCAC


 


351
TTCACGCCCT GCCCGTTTCA TGGCGCGGCA GAACACGTCG TCCGCATTCA


 


401
AAACCTGCAC TCCATCGCCA CGGAAAATCT CGGCTTTGGT ATGCGCGTAG






This corresponds to the amino acid sequence <SEQ ID 290; ORF 089.ng>:










g089.pep




1
MPPKITKSGF CKPAIAAAVA PTFVPLLSSM NTTPFFSPIF STRCGKPWKV



 


51
LTCSSNASRG KPTASHKATA AITLAALCKP CSGMSCVEIK SSLPCFKQPV


 


101
PRSNQKSASC SKENRFTSRP ARFMARQNTS SAFKTCTPSP RKISALVCA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 291>:










m089.seq




1
ATGCCGCCCA AAATCACkAw GAGCGGATTT TGCAAACCGG CAATCGCGGC



 


51
GGCAGTCGCG CCGACATTCG TGCCTTTGCT GTCGTCGATA AACACCACGC


 


101
CGTTTTTCTC GCCGATTTTT TCCACGCGGT GCGGCAGGCC TTGGAAGGTT


 


151
TTGACGTGTT CGAGCAATGC TTCGCGCGAC AAACCGATGG CCTCACACAA


 


201
AGCCACkGCA GCCATGACGT TAGCGGCGTT GTGCAkACCT TGCAACGGwA


 


251
TGTCTTGCGT GACAATCAAA TCTTCATTGC CTTGTTTCAG GCGGCCTGTC


 


301
TCGCGTTCCA ACCAGAAATC AGCTTCGTGT TCCAACGAAA ACCATTTTAC


 


351
CTCGCGCCCG GCACGCTTCA TCGCGCGGCA GAACGCATCG TCCGCATTCA


 


401
AAACCTGCAC GCCGTCGCCA CGGAAAATCT TGGCTTTGGT ATGCGCATAG






This corresponds to the amino acid sequence <SEQ ID 292; ORF 089>:










m089.pep




1
MPPKITXSGF CKPAIAAAVA PTFVPLLSSI NTTPFFSPIF STRCGRPWKV



 


51
LTCSSNASRD KPMASHKATA AMTLAALCXP CNGMSCVTIK SSLPCFRRPV


 


101
SRSNQKSASC SNENHFTSRP ARFIARQNAS SAFKTCTPSP RKILALVCA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 089 shows 88.6% identity over a 149 aa overlap with a predicted ORF (ORF 089.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 293>:










a089.seq




1
ATGCCGCCTA AAATCACGAA GAGCGGATTT TGCAAACCGG CAATCGCGGC



 


51
GGCGGTCGCA CCGACGTTCG TGCCTTTGCT GTCGTCGATG AACACCACGC


 


101
CATTTTTCTC GCCGATTTTT TCCACGCGGT GCGGCAGGCC TTGAAAGGTT


 


151
TTGACGTGTT CGAGCAATGC TTCGCGCGGC AAACCGACGG CTTCGCACAA


 


201
GGCAACGGCA GCCATCACGT TAGTGGCGTT GTGCAAGCCT TGCAGCGGAA


 


251
TATCTTGCGT GGCAATCAAA TCTTCATTGC CTTGTTTCAG GCGACCTGTC


 


301
TCACGTTCCA ACCAAAAATC GGCTTCGTAT TCCAACGAAA ACCATTTCAC


 


351
CTCGCGCCCG GCGCGCTTCA TCGCACGACA GAACGCATCG TCCGCATTCA


 


401
AAACCTGCAC ACCGTCGCCA CGGAAAATCT TGGCTTTGGT ATGCGCGTAG






This corresponds to the amino acid sequence <SEQ ID 294; ORF 089.a>:










a089.pep




1
MPPKITKSGF CKPAIAAAVA PTFVPLLSSM NTTPFFSPIF STRCGRP*KV



 


51
LTCSSNASRG KPTASHKATA AITLVALCKP CSGISCVAIK SSLPCFRRPV


 


101
SRSNQKSASY SNENHFTSRP ARFIARQNAS SAFKTCTPSP RKILALVCA*






m089/a089 91.9% identity over a 149 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 295>:










g090.seq




1
ATGCGCGTAG TCGAGCAAAT CGTCGTAGCG GTCGAGATGG TCTTCGGAAA



 


51
TGTTCATCAC CGTCGCCGCA GTCGGGCGCA GGCTTTCGGT GTTTTCCAGT


 


101
TGGAAGCTGG AAAGCTCcca CACCCACACG TCCGCCTTTT TGCCTTCgcg


 


151
ctgCAATtct gcctccaaga cgggcgtacc gatATTGCCC GCAATGAcgg


 


201
tatccagccc gcacttgatg CAGAGatagc ggaccaggct ggttaccgTG


 


251
GTTttgccgt tgctgCcggt aatcgCaatc accttgtcgC CGCGGCGGtt


 


301
cAcaaTGTCc gccaGCAATt ggATGTCGCC TAgCACGCGC .ccgccgTTT


 


351
TGCttga






This corresponds to the amino acid sequence <SEQ ID 296; ORF 090.ng>:










g090.pep




1
MRVVEQIVVA VEMVFGNVHH RRRSRAQAFG VFQLEAGKLP HPHVRLFAFA



 


51
LQFCLQDGRT DIARNDGIQP ALDAEIADQA GYRGFAVAAG NRNHLVAAAV


 


101
HNVRQQLDVA XHAXRRFA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 297>:










m090.seq




1
ATGCGCATAG TCGAGCAAGT CGTCGTAGCG GTCGAGATGG TCTTCGGAAA



 


51
TGTTCAGCAC CGTCGCCGCA GTCGGACGCA GGCTTTCGGT GTTTTCCAGT


 


101
TGGAAGCTGG AAAGCTCCAA CACCCACACG TCCGCCTTTT TGCCTTCGCG


 


151
CTGCCATTCC GCCTCCAAAA CCGGCGTGCC GATATTGCCC GCGATAACGG


 


201
TATCCAGCCC GCACTTGATA CAGAGATAGC CGACCAGGCT CGTTACCGTG


 


251
GTTTTGCCGT TGCTGCCGGT AATCGCAATT ACCTTGTCGT CCCGGCGGTT


 


301
CACAATGTCC GCCAGCAATT CGATGTCGCC CAACACGCGT .CCGCCGTTT


 


351
TGCTTGA






This corresponds to the amino acid sequence <SEQ ID 298; ORF 090>:










m090.pep




1
MRIVEQVVVA VEMVFGNVQH RRRSRTQAFG VFQLEAGKLQ HPHVRLFAFA



 


51
LPFRLQNRRA DIARDNGIQP ALDTEIADQA RYRGFAVAAG NRNYLVVPAV


 


101
HNVRQQFDVA QHAXRRFA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 090 shows 83.9% identity over a 118 aa overlap with a predicted ORF (ORF 090.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 299>:










a090.seq




1
ATGCGCGTAG TCGAGCAAGT CGTCGTAGCG GTCGAGATGG TCTTCGGAAA



 


51
TGTTCAGCAC TGTCGCCGCA GTCGGGCGCA GGCTTTCGGT GTTTTCCAGT


 


101
TGGAAACTGG AAAGCTCCAA CACCCACACG TCCGCCTTTT TGCCTTCGCG


 


151
CTGCAATTCC GCCTCCAAAA CCGGCGCGCC GATATTGCCC GCGATAACGG


 


201
TATCCAGCCC ACACTTGATG CAGAGATAGC CGACCAGGCT CGTTACCGTG


 


251
GTTTTGCCGT TGCTGCCGGT AATCGCAATC ACCTTGTCGC CGCGGCGGTT


 


301
CACAATGTCC GCCAGCAATT CGATGTCGCC CAACACGCGT C.CGCCGTTT


 


351
CGCTTAA






This corresponds to the amino acid sequence <SEQ ID 300; ORF 090.a>:










a090.pep




1
MRVVEQVVVA VEMVFGNVQH CRRSRAQAFG VFQLETGKLQ HPHVRLFAFA



 


51
LQFRLQNRRA DIARDNGIQP TLDAEIADQA RYRGFAVAAG NRNHLVAAAV


 


101
HNVRQQFDVA QHAXRRFA*






m09/a090 91.5% identity over a 117 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae 

g090-1.seq This sequence contains multiple stop codons (not shown)

This corresponds to the amino acid sequence <ORF 090-1.ng>:

g090-1.pep (not shown)

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2>:










m090-1.seq




1
ATGACGGCGT TTGCATTTCA GACGGCATCA CAAAGCCTTA AACGCTTCGA



 


51
TAAACACTTC CGAACGGTGC GCGTAGCCTT TGAACATATC AAAGCTCGCG


 


101
CAGGCGGGGC TGAGCAACAC AATATCGCCT GCTTCGGCTT GGGCATATGC


 


151
CGTCTGAACG GCTTCTCCCA AAGTGGCGCA GTCGGTCATA TTCAAGCCGC


 


201
AGCCGTCCAA ATCGCGGCGG ATTTGCGGCG CATCGACACC AATCAAGAAC


 


251
ACGCCTTTTG CCTTGCCTAC CAGTGCATCG CGCAGGGGCG TGAAGTCCTG


 


301
CCCTTTACCC ATGCCGCCCA AAATCACGAA GAGCGGATTT TGCAAACCGG


 


351
CAATCGCGGC GGCAGTCGCG CCGACATTCG TGCCTTTGCT GTCGTCGATA


 


401
AACACCACGC CGTTTTTCTC GCCGATTTTT TCCACGCGGT GCGGCAGGCC


 


451
TTGGAAGGTT TTGACGTGTT CGAGCAATGC TTCGCGCGAC AAACCGATGG


 


501
CCTCACACAA AGCCACGGCA GCCATGACGT TAGCGGCGTT GTGCAGACCT


 


551
TGCAACGGAA TGTCTTGCGT GACAATCAAA TCTTCATTGC CTTGTTTCAG


 


601
GCGGCCTGTC TCGCGTTCCA ACCAGAAATC AGCTTCGTGT TCCAACGAAA


 


651
ACCATTTTAC CTCGCGCCCG GCACGCTTCA TCGCGCGGCA GAACGCATCG


 


701
TCCGCATTCA AAACCTGCAC GCCGTCGCCA CGGAAAATCT TGGCTTTGGT


 


751
ATGCGCATAG TCGAGCAAGT CGTCGTAGCG GTCGAGATGG TCTTCGGAAA


 


801
TGTTCAGCAC CGTCGCCGCA GTCGGACGCA GGCTTTCGGT GTTTTCCAGT


 


851
TGGAAGCTGG AAAGCTCCAA CACCCACACG TCCGCCTTTT TGCCTTCGCG


 


901
CTGCCATTCC GCCTCCAAAA CCGGCGTGCC GATATTGCCC GCGATAACGG


 


951
TATCCAGCCC GCACTTGATA CAGAGATAGC CGACCAGGCT CGTTACCGTG


 


1001
GTTTTGCCGT TGCTGCCGGT AATCGCAATT ACCTTGTCGT CCCGGCGGTT


 


1051
CACAATGTCC GCCAGCAATT CGATGTCGCC CAACACGCGT CCGCCGTTTT


 


1101
GCTTGAACGC CTCAATATCC GGCTGCCGCT CGCTGATGCC GGGACTGAGA


 


1151
GCCAGAATAT CGAAACCGTT GTCCAGCGCA TCTTTCAGAC GGCCCGTGTA


 


1201
AAACACCAAC CCGTCAAACA TCTTACCGAT TTGCGACACG CGTTCCGGCT


 


1251
TCAGCTCCGC ATCATACGCA GCAACCTCCG CGCCGTTTTT GCGCAGGTAG


 


1301
GCAATCATGG AAATACCCGT ACCGCCGAGT CCGGCGACGA GGATTTTTTT


 


1351
GTTTTGAAAA GTCATTTTGG TTTGTCCTAA






This corresponds to the amino acid sequence <SEQ ID 3; ORF 090-1>:










m090-1.pep




1
MTAFAFQTAS QSLKRFDKHF RTVRVAFEHI KARAGGAEQH NIACFGLGIC



 


51
RLNGFSQSGA VGHIQAAAVQ IAADLRRIDT NQEHAFCLAY QCIAQGREVL


 


101
PFTHAAQNHE ERILQTGNRG GSRADIRAFA VVDKHHAVFL ADFFHAVRQA


 


151
LEGFDVFEQC FARQTDGLTQ SHGSHDVSGV VQTLQRNVLR DNQIFIALFQ


 


201
AACLAFQPEI SFVFQRKPFY LAPGTLHRAA ERIVRIQNLH AVATENLGFG


 


251
MRIVEQVVVA VEMVFGNVQH RRRSRTQAFG VFQLEAGKLQ HPHVRLFAFA


 


301
LPFRLQNRRA DIARDNGIQP ALDTEIADQA RYRGFAVAAG NRNYLVVPAV


 


351
HNVRQQFDVA QHASAVLLER LNIRLPLADA GTESQNIETV VQRIFQTARV


 


401
KHQPVKHLTD LRHAFRLQLR IIRSNLRAVF AQVGNHGNTR TAESGDEDFF


 


451
VLKSHFGLS*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 303>:










g091.seq




1
ATGGAAATAC CCGTGCCGCC AAGTCCGGCG ACGAGGATTT TTTTGTTTGA



 


51
AAGTCATTTT GGTTTTGTCC TAAAACAAAT CATATTGGGC AGGAGACGTC


 


101
CGCCCTTGCC CAAGCCGCTT TCAGACGGCA TCGCGAGCCG ATTAATAACC


 


151
CGCCTTCAGG CGTTGGTCAT TGTCGCAGCT GTTTTGGTCT CCGTTTTGAC


 


201
AAGCCTTGCC AAGCCATTGT TGAGCGAGCG CAAGGTCTTG GCGCACGCCG


 


251
CGTCCATCGT AATACATCAA GCCCAAATTG TATTGGGCTT GGGCATCCCC


 


301
TTGTTCTGA






This corresponds to the amino acid sequence <SEQ ID 304; ORF 091.ng>:










g091.pep




1
MEIPVPPSPA TRIFLFESHF GFVLKQIILG RRRPPLPKPL SDGIASRLIT


 


51
RLQALVIVAA VLVSVLTSLA KPLLSERKVL AHAASIVIHQ AQIVLGLGIP


 


101
LF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 305>:










m091.seq




1
ATGGAAATAC CCGTACCGCC GAGTCCGGCG ACGAGGATTT TTTTGTTTGA


 


51
AAAGTCATTT TGGTTTGTCC TAAAACAAAT CATATTGAGC AGGAGATGTC


 


101
CGCCCCTGCC CAAGCCGCTT TCAGACGGCA TCGCGAGCTG TTCAATAACC


 


151
CGCCTTCAGG CGTTGGTCAT TGTCGCAGCC GTCTTGGTCT CCGTTTTGAC


 


201
AAGCCTTGCC AAACCATTCT TGTGCAAGGG CGCGGTCTTG GCGCACGCCG


 


251
CGTCTTTCGG CATACATCAC GCCCAAATTG TTTTGGGCTT GGGCTACCCC


 


301
CTGCGC...






This corresponds to the amino acid sequence <SEQ ID 306; ORF 091>:










m091.pep




1
MEIPVPPSPA TRIFLFEKSF WFVLKQIILS RRCPPLPKPL SDGIASCSIT


 


51
RLQALVIVAA VLVSVLTSLA KPFLCKGAVL AHAASFGIHH AQIVLGLGYP


 


101
LR.






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 091 shows 84.2% identity over a 101 aa overlap with a predicted ORF (ORF 091.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitides <SEQ ID 307>:










a091.seq




1
ATGGAAATAC CCGTGCCGCC AAGTCCGGCG ACGAGGATTT TTTTGTTTTG


 


51
GAAATCATTT TGGTTTGTCC TAAAACAAAT CATATTGAGC AGGGGATGTC


 


101
TGATCCTGCT CAAGCCGCTT TCAGACGGCA TCGCGAGCTG TTCAATAACC


 


151
CGCTTTCAGG CGTTGGTCAT TGTCGCAGCT GTCTTGGTAT CCGTTTTGAC


 


201
AAGCCTTGCC AAGCCATTCT TGTGCAAGGG CGCGGTCTTG GCGCACGCCG


 


251
CGTCTTTCGG CATACATCAC GCCCAAATTG TTTTGGGC






This corresponds to the amino acid sequence <SEQ ID 308; ORF 091.a>:










a091.pep




1
MEIPVPPSPA TRIFLFWKSF WFVLKQIILS RGCLILLKPL SDGIASCSIT


 


51
RFQALVIVAA VLVSVLTSLA KPFLCKGAVL AHAASFGIHH AQIVLG






m091/a091 93.8% identity over a 96 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 309>:










g092.seq




1
ATGTTTTTTA TTTCAATCCG CTATATATTT GTCAGAAAAC TATGGTGCGC


 


51
AAACGGTCAG ACCTTTAAAA TAACGCCTTT ACGCACTAAA AACCAACCGG


 


101
AACGCAACAT TATGATGAAA AATCGAGTAA GCAACATCCA TTTTGTCGGT


 


151
ATCGGCGGCG TCGGCATGAG CGGTATCGCC GAAGTCTTGC ACAATTTGGG


 


201
CTTTAAAGTT TCCGGTTCGG ATCAGGCGCG AAATGCCGCT ACCGAGCATT


 


251
TGAGCAGCCT GGGCATTCAA GTTTATCCCG GCCATACCGC AGAACACGTT


 


301
AACGGTgcgg ATGTCGTCGT TGCCTCTACC GCCGTCAAGA AAGAAaatcC


 


351
CGAAGTtgtc gcTGCGTTGG AGCGGCAAAT TCCCGTTATT CCGCGCGCCT


 


401
TGATGCTGGC AGAGCTGATG CGCTTCCGTG ACGgcatcgc cattgccggT


 


451
ACGCACGGCA AAACCACGAC CACCAGCCTG ACCGCCTCCA TCCTCGGCGC


 


501
GGCAGGACTC GACCCCACTT TCGTTATCGG CGGCAAACTC AACGCCGCAG


 


551
GCACCAACGC CCGCTTGGGC AAAGGCGAAT ACATCGTTGC CGAAGCCGAC


 


601
GAATCCGATG CCTCTTTCCT ACATCTGACC CCGATTATGT CCGTCGTTAC


 


651
CAATATCGAC GAAGACCATA TGGATACCTA CGGGCACAGC GTCGAAAAAC


 


701
TGCATCAGGC GTTTATCGAT TTCATCCACC GTATGCCCTT CTACGGCAAA


 


751
GCCTTTTTGT GTGTTGACAG CGAACACGTC CGCGCGATTT TGCCCAAAGT


 


801
GAGCAAACCT TATGCTACTT ACGGTTTGGA CGATACCGCC GACATCTACG


 


851
CCACCGACAT CGAAAACGTC GGCGCGCAAA TGAAATTCAC CGTCCATGTT


 


901
CAAATGAAAG GACATGAGCA GGGGTCGTTT GAAGTCGTGC TGAATATGCC


 


951
CGGCAGACAC AACGTGCTGA ACGCATTGGC AGCCATCGGc gtggcGCTgg


 


1001
aagtcGgCGC ATcggttgAA GCGAtcCAAA AaggCTTGCT CGGCTTTGAA


 


1051
GGCGTCGGCC GCCGCTTCCA AAAATAcggc gacatCAagt tgccaaacgg


 


1101
cggGaccgCT TTgctGGTGG ACGATTAcgg ACACCACCCC GTCGAAATGG


 


1151
CGGcaaccct tgccgcTGCA CGCGGCGCGT ATCCGGAAAA acgtTTGGTG


 


1201
CtcgCCTTCC AGCCGCACCG CTATACCCGC ACGCGCGATT TGTTTGAAGA


 


1251
CTTTACCAAA GTACTCAATA CCGTTGatgC GCTGGTACTG ACCGAAGTTT


 


1301
AtgccgccgG CGAAGAGCCG GTTGCCGCCG CCGactcCCG CGCCTTGGCG


 


1351
CGTGCTATCC GCGTATTGGG CAAACTTGAG CCGATTTACT GCGAAAatgt


 


1401
cgccgACCTG CCGCAAATGC TGATGAATGT TTTACAGGAT Ggcgatgttg


 


1451
tgttgAATAT GggTgcggga agcatcaacc gcgttccttc cgcgctgttg


 


1501
gaattgtcga AACAGAtttg A






This corresponds to the amino acid sequence <SEQ ID 310; ORF 092.ng>:










g092.pep




1
MFFISIRYIF VRKLWCANGQ TFKITPLRTK NQPERNIMMK NRVSNIHFVG


 


51
IGGVGMSGIA EVLHNLGFKV SGSDQARNAA TEHLSSLGIQ VYPGHTAEHV


 


101
NGADVVVAST AVKKENPEVV AALERQIPVI PRALMLAELM RFRDGIAIAG


 


151
THGKTTTTSL TASILGAAGL DPTFVIGGKL NAAGTNARLG KGEYIVAEAD


 


201
ESDASFLHLT PIMSVVTNID EDHMDTYGHS VEKLHQAFID FIHRMPFYGK


 


251
AFLCVDSEHV RAILPKVSKP YATYGLDDTA DIYATDIENV GAQMKFTVHV


 


301
QMKGHEQGSF EVVLNMPGRH NVLNALAAIG VALEVGASVE AIQKGLLGFE


 


351
GVGRRFQKYG DIKLPNGGTA LLVDDYGHHP VEMAATLAAA RGAYPEKRLV


 


401
LAFQPHRYTR TRDLFEDFTK VLNTVDALVL TEVYAAGEEP VAAADSRALA


 


451
RAIRVLGKLE PIYCENVADL PQMLMNVLQD GDVVLNMGAG SINRVPSALL


 


501
ELSKQI*






The following partial DNA sentence was identified in N. meningitidis <SEQ ID 311>:










m092.seq




1
ATGTTTTTTA TTTCAATCCG CTATATATTT GTCAGAAAAC TATGGCGCGC


 


51
AAACGGTCAG CCCTTTAAAA TAACGCCTTT ACGCATCGAA AATCCACCGG


 


101
AACGCAACAT TATGATGAAA AATCGAGTTA CCAACATCCA TTTTGTCGGT


 


151
ATCGGCGGCG TCGGCATGAG CGGCATCGCC GAAGTCTTGC ACAATTTGGG


 


201
CTTTAAAGTT TCCGGTTCGG ATCAgGCGCG AAATGCCGCT ACCGAGCATT


 


251
TGGGCAGCCT GGGCATTCAA GTTTATCCCG GCCATACCGC CGAACACGTT


 


301
AACGGTGCGG ATGTCGTCGT TACCTCTACC GCCGTCAAAA AAGAAAATCC


 


351
CGAAGTTGTC GCTGCGTTGG AGCAGCAAAT TCCCGTTATT CCGCGCGCCC


 


401
TGATGTTGGC GGAGTTGATG CGCTTCCGTG ACGGCATCGC CATTGCCGGC


 


451
ACGCACGGCA AAACCACGAC CACCAGCCTG ACCGCCTCCA TCCTCGGCGC


 


501
GGCAGGACTT GACCCGACTT TCGTTATCGG CGGCAAACTC AACGCCGCAG


 


551
GCACTAACGC CCGCTTGGGC AAAGGCGAAT ACATCGTTGC CGAAGCCGAC


 


601
GAGTCGGATG CATCCTTTCT GCACCTGACA CCGATTATGT CCGTCGTTAC


 


651
CAATATCGAC GAAGACCATA TGGATACCTA CGGGCACAGC GTCGAAAAAC


 


701
TGCATCAGGC GTTTATCGAT TTCATCCACC GTATGCCCTT CTACGGCAAA


 


751
GCCTTTTTGT GTATTGACAG CGAACACGTC CGCGCGATTT TGCCCAAAGT


 


801
GAGCAAACCT TATGCTACTT ACGGTTTGGA CGATACCGCC GACATCTACG


 


851
CCACCGACAT CGAAAACGTC GGCGCGCAAA TGAAATTCAC CGTCCATGTT


 


901
CAAATGAAAG GACATGAGCA GGGGTCGTTT GAAGTCGTGC TGAATATGCC


 


951
CGGCAGACAC AACGTGCTGA ACGCATTGGC AGCCATCGGC GTGGCGCTGG


 


1001
AAGTCGGCGC ATCGGTTGAA GCGATCCAAA AAGGCTTGCT CGGCTTTGAA


 


1051
GGCGTCGGCC GCCGCTTCCA AAAATACGGC GACATCAAGT TGCCAAACGG


 


1101
CGGGACCGCG CTCTTGGTGG ACGACTACGG ACACCACCCC GTCGAAATGG


 


1151
CGGCGACCCT TGCCGCCGCA CGCGGCGCGT ATCTGGAAAA ACGTTTGGTA


 


1201
CTCGCCTTCC AGCCGCACCG CTATACCCGC ACGCGCGATT TGTTTGAAGA


 


1251
CTTTACCAAA GTCCTCAATA CCGTTGACGC GCTGGTGCTG ACCGAAGTTT


 


1301
ATGCCGCCGG TGAAGAGCCG ATTGCCGCCG CCGATTCCCG CGCTCTTGCC


 


1351
CGCGCCATCC GCGTGTTGGG CAAACTCGAG CCGATTTACT GCGAAAACGT


 


1401
TGCCGATCTG CCCGAAATGC TGTTGAACGT TTTGCAGGAC GGCGACATCG


 


1451
TGTTGAATAT GGGCGCGGGA AGCATCAACC GCGTCCCCGC CGCGCTGCTG


 


1501
GCATTGTCGA AACAGATTTG A






This corresponds to the amino acid sequence <SEQ ID 312; ORF 092>:










m092.pep




1
MFFISIRYIF VRKLWRANGQ PFKITPLRIE NPPERNIMMK NRVTNIHFVG


 


51
IGGVGMSGIA EVLHNLGFKV SGSDQARNAA TEHLGSLGIQ VYPGHTAEHV


 


101
NGADVVVTST AVKKENPEVV AALEQQIPVI PRALMLAELM RFRDGIAIAG


 


151
THGKTTTTSL TASILGAAGL DPTFVIGGKL NAAGTNARLG KGEYIVAEAD


 


201
ESDASFLHLT PIMSVVTNID EDHMDTYGHS VEKLHQAFID FIHRMPFYGK


 


251
AFLCIDSEHV RAILPKVSKP YATYGLDDTA DIYATDIENV GAQMKFTVHV


 


301
QMKGHEQGSF EVVLNMPGRH NVLNALAAIG VALEVGASVE AIQKGLLGFE


 


351
GVGRRFQKYG DIKLPNGGTA LLVDDYGHHP VEMAATLAAA RGAYLEKRLV


 


401
LAFQPHRYTR TRDLFEDFTK VLNTVDALVL TEVYAAGEEP IAAADSRALA


 


451
RAIRVLGKLE PIYCENVADL PEMLLNVLQD GDIVLNMGAG SINRVPAALL


 


501
ALSKQI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 092 shows 96.6% identity over a 506 aa overlap with a predicted ORF (ORF 092.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 313>:










a092.seq




1
ATGTTTTTTA TTTCAATCCG CTATATATTT GTCAGAAAAC TATGGCGCGC


 


51
AAACGGTCAG CCCTTTAAAA TAACGCCTTT ACGCATCGAA AATCCACCGG


 


101
AACGCAACAT TATGATGAAA AATCGAGTGA CCAACATCCA TTTTGTCGGT


 


151
ATCGGCGGCG TCGGCATGAG CGGTATCGCC GAAGTCTTGC ACAATTTGGG


 


201
TTTTAAAGTT TCCGGTTCGG ATCAGGCGCG AAATGCCGCT ACCGAGCATT


 


251
TGGGCAGCCT GGGCATTCAA GTTTATCCCG GCCATACCGC AGAACACGTT


 


301
AACGGTGCGG ATGTCGTCGT TACCTCTACC GCCGTCAAAA AAGAAAATCC


 


351
CGAAGTTGTC GCTGCGTTGG AGCAGCAAAT TCCCGTTATT CCGCGCGCCC


 


401
TGATGTTGGC GGAGTTGATG CGCTTCCGTG ACGGCATCGC CATTGCCGGC


 


451
ACGCACGGCA AAACCACGAC CACCAGCCTG ACCGCCTCCA TCCTCGGCGC


 


501
GGCAGGACTT GACCCGACTT TCGTTATCGG CGGCAAACTC AACGCCGCAG


 


551
GCACCAACGC CCGCTTGGGC AAAGGCGAAT ACATCGTTGC CGAAGCCGAC


 


601
GAGTCGGATG CATCCTTTCT GCACCTGACA CCGATTATGT CCGTCGTTAC


 


651
CAATATCGAC GAAGACCATA TGGATACCTA CGGGCACAGT GTTGAGAAGC


 


701
TGCATCAGGC GTTTATCGAT TTCATCCACC GTATGCCCTT CTACGGCAAA


 


751
GCCTTTTTGT GTATTGACAG CGAACACGTC CGCGCGATTT TGCCCAAAGT


 


801
GAGCAAACCT TATGCTACTT ACGGTTTGGA CGATACCGCC GACATCTACG


 


851
CCACCGACAT CGAAAACGTC GGCGCGCAAA TGAAATTCAC CGTCCATGTT


 


901
CAAATGAAAG GACATGAGCA GGGGTCGTTT GAAGTCGTGC TGAATATGCC


 


951
CGGCAGACAC AACGTGCTGA ACGCATTGGC AGCCATCGGC GTGGCGCTGG


 


1001
AAGTCGGCGC ATCGGTTGAA GCGATCCAAA AAGGCTTGCT CGGCTTTGAA


 


1051
GGTGTCGGCC GCCGCTTCCA AAAATACGGC GACATCAAGT TGCCAAACGG


 


1101
TGGAACCGCG CTCTTGGTGG ACGACTACGG ACACCACCCC GTCGAAATGG


 


1151
CGGCGACCCT TTCCGCCGCA CGCGGCGCGT ATCCGGAAAA ACGTTTGGTA


 


1201
CTCGCCTTCC AGCCGCACCG CTATACCCGC ACGCGCGATT TGTTTGAAGA


 


1251
CTTTACCAAA GTCCTCAATA CCGTTGACGC GCTGGTGCTG ACCGAAGTTT


 


1301
ATGCCGCCGG TGAAGAGCCG ATTGCCGCCG CTGATTCCCG CGCTCTTGCC


 


1351
CGCGCCATCC GCGTGTTGGG CAAACTCGAG CCGATTTACT GCGAAAACGT


 


1401
TGCCGATCTG CCCGAAATGC TGTTGAACGT TTTGCAGGAC GGCGACATCG


 


1451
TGTTGAATAT GGGTGCGGGA AGCATCAACC GCGTCCCCGC CGCGCTGCTG


 


1501
GAATTGTCGA AACAGATTTG A






This corresponds to the amino acid sequence <SEQ ID 314; ORF 092.a>:










a092.pep




1
MFFISIRYIF VRKLWRANGQ PFKITPLRIE NPPERNIMMK NRVTNIHFVG


 


51
IGGVGMSGIA EVLHNLGFKV SGSDQARNAA TEHLGSLGIQ VYPGHTAEHV


 


101
NGADVVVTST AVKKENPEVV AALEQQIPVI PRALMLAELM RFRDGIAIAG


 


151
THGKTTTTSL TASILGAAGL DPTFVIGGKL NAAGTNARLG KGEYIVAEAD


 


201
ESDASFLHLT PIMSVVTNID EDHMDTYGHS VEKLHQAFID FIHRMPFYGK


 


251
AFLCIDSEHV RAILPKVSKP YATYGLDDTA DIYATDIENV GAQMKFTVHV


 


301
QMKGHEQGSF EVVLNMPGRH NVLNALAAIG VALEVGASVE AIQKGLLGFE


 


351
GVGRRFQKYG DIKLPNGGTA LLVDDYGHHP VEMAATLSAA RGAYPEKRLV


 


401
LAFQPHRYTR TRDLFEDFTK VLNTVDALVL TEVYAAGEEP IAAADSRALA


 


451
RAIRVLGKLE PIYCENVADL PEMLLNVLQD GDIVLNMGAG SINRVPAALL


 


501
ELSKQI*






m092/a092 99.4% identity over a 506 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 315>:










g093.seq




1
aTGCAGAATt ttgGCAAAGT ggccgtATTG ATGGGtggtT TTTCCAGCGA


 


51
ACGAGAaatc tcgcTGGACA GCgGTACCGC CATTTTGAAC GCCTTAAAAA


 


101
GCAAAGGCAT AGACGCATAC GCCTTCGACC CTAAGGAAAC GCCGTTATCC


 


151
GAACTGAAGG AGCGGGGCTT TCAGACGGCA TTCAACATCC TTCACGGTAC


 


201
TTACGGCGAA GACGGGGCTG TTCAGGGTGC ATTGGAACTG TTGGGCATTC


 


251
CCTATACCGG CAGCGGTGTC GCCGCCTCCG CCATCGGCAT GGACAAATAC


 


301
CGCTGCAAAC TGATTTGGCA GGCATTGGGA TTACCCGTTC CCGAGTTCGC


 


351
CGTACTGTAC GATGATACCG ATTTCGATGC CGTCGAAGAA AAATTGGGTC


 


401
TGCCGATGTT TGTGAAGCCG GCGGCCGAAG GCAGCAGCgt cggcgtggta


 


451
aAAGTCAAAG AAAaaggccg TCTGAAAAGC GTTtacgaag aatTGAaaCA


 


501
CCTTcagggg cgaAAtcatt gccgAacgTT TTATCGGCGG CGGCGAATAT


 


551
TCCTGCCCCG TCCTGAACGG CAAAGGGCTG CCCGGCATAC ACATCATCCC


 


601
CGCAACCGAG TTTTACGAct acgaagccaa GtacaaCCGA GACGAcacca


 


651
tttaTCAATG TCCTTCGGAA GATTTGACCG AAGCCGAAGA AAGCCTGATG


 


701
CGCGAACTGG CGGTTCGCGG CGCACAGGCA ATCGGTGCGG AAGGCTGCGT


 


751
GCGCGTCGAT TTCCTCAAAG ATACCGACGG CAAACTCTAT CTGTTGGAAA


 


801
TCAACACCCT GCCCGGTATG ACCGGCCATA G






This corresponds to the amino acid sequence <SEQ ID 316; ORF 093.ng>:










g093.pep




1
MQNFGKVAVL MGGFSSEREI SLDSGTAILN ALKSKGIDAY AFDPKETPLS


 


51
ELKERGFQTA FNILHGTYGE DGAVQGALEL LGIPYTGSGV AASAIGMDKY


 


101
RCKLIWQALG LPVPEFAVLY DDTDFDAVEE KLGLPMFVKP AAEGSSVGVV


 


151
KVKEKGRLKS VYEELKHLQG RNHCRTFYRR RRIFLPRPER QRAARHTHHP


 


201
RNRVLRLRSQ VQPRRHHLSM SFGRFDRSRR KPDARTGGSR RTGNRCGRLR


 


251
ARRFPQRYRR QTLSVGNQHP ARYDRP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 317>:










m093.seq




1
ATGCAGAATT TTGGCAAAGT GGCCGTATTG ATGGGCGGTT TTTCCAGCGA


 


51
ACGAGAAATC TCGCTGGACA GCGGCACCGC CATTTTGAAT GCTTTAAAAA


 


101
GCAAAGGCAT AGACGCATAC GCCTTCGATC CTAAAGAAAC CCCATTGTCT


 


151
GAATTGAAGG CACAAGGTTT TCAGACGGCA TTCAACATCC TTCACGGTAC


 


201
TTACGGCrAA GACGGGGCGG TTCAGGGTGC ATTGGAACTG TTGGGCATTC


 


251
CCTATACCGG CAGCGGTGTC GCCGCATCCG CCATCGGCAT GGACAAATAC


 


301
CGCTGCAAAC TGATTTGGCA GGCATTGGGA TTGCCCGTTC CCGAGTTCGC


 


351
CGTCCTGCAC GACGACACTG ATTTCGATGC CGTCGAAGAA AAATTGGGCC


 


401
TGCCGATGTT TGTGAAACCG GCGGCCGAAG GCAGCAGCGT AGGCGTGGTA


 


451
AAAGTCAAAG GAAAAGGCCG TCTGAAAAGC GTTTACGAAG AATTGAAACA


 


501
CCTTCAGGG. CGAAATCATT GCCGAACGTT TTATCGGCGG CGGCGAATAT


 


551
TCCTGCCCCG TCCTGAACGG CAAAGGGCTG CCCGGCATAC ACATCATTCC


 


601
CGCAACCGAG TTTTACGACT ACGAAGCCAA GTACAACCGC GACGACACCA


 


651
TTTATCAATG TCCTTCGGAA GATTTGACCG AAGCCGAAGA AAGCCTGATG


 


701
CGCGAACTGG CGGTTCGCGG CGCGCAGGCA ATCGGTGCGG AAGGCTGCGT


 


751
GCGCGTCGAT TTCCTCAAAG ATACCGACGG CAAACTCTAT CTGTTGGAAA


 


801
TCAACACCCT GCCCGGTATG ACGAGCCATA G






This corresponds to the amino acid sequence <SEQ ID 318; ORF 093>:










m093.pep




1
MQNFGKVAVL MGGFSSEREI SLDSGTAILN ALKSKGIDAY AFDPKETPLS


 


51
ELKAQGFQTA FNILHGTYGX DGAVQGALEL LGIPYTGSGV AASAIGMDKY


 


101
RCKLIWQALG LPVPEFAVLH DDTDFDAVEE KLGLPMFVKP AAEGSSVGVV


 


151
KVKGKGRLKS VYEELKHLQX RNHCRTFYRR RRIFLPRPER QRAARHTHHS


 


201
RNRVLRLRSQ VQPRRHHLSM SFGRFDRSRR KPDARTGGSR RAGNRCGRLR


 


251
ARRFPQRYRR QTLSVGNQHP ARYDEP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 093 shows 96.7% identity over a 276 aa overlap with a predicted ORF (ORF 093.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 319>:










a093.seq




1
ATGCAGAATT TTGGCAAAGT GGCCGTATTG ATGGGCGGTT TTTCCAGCGA


 


51
ACGAGAAATC TCGCTGGACA GCGGCACCGC CATTTTGAAT GCTTTAAAAA


 


101
GCAAAGGCAT AGACGCATAC GCCTTCGATC CCAAGGAAAC CCCATTGTCT


 


151
GAATTGAAGG CACAAGGTTT TCAGACGGCA TTCAACATCC TTCACGGTAC


 


201
TTACGGCGAA GACGGGGCTG TTCAGGGTGC ATTGGAACTG TTGGGCATTC


 


251
CCTATACCGG CAGCGGTGTC GCCGCATCCG CCATCGGCAT GGACAAATAC


 


301
CGCTGCAAAC TGATTTGGCA GGCATTGGGA TTGCCCGTTC CCGAGTTCGC


 


351
CGTCCTGCAC GACGACACTG ATTTCGATGC CGTCGAAGAA AAATTGGGCC


 


401
TGCCGATGTT TGTGAAACCG GCGGCCGAAG GCAGCAGCGT AGGCGTGGTA


 


451
AAAGTCAAAG GAAAAGGCCG TCTGAAAAGC GTTTACGAAG AATTGAAACA


 


501
CTTTCAGGG. CGAAATCATT GCCGAACGGT TTATCGGCGG CGGCGAATAT


 


551
TCCTGCCCTG TGTTGAACGG CAAAGGCCTG CCCGGCATAC ACATCATCCC


 


601
CGCGACCGAG TTTTATGACT ACGAAGCCAA GTACAACCGC AACGACACCA


 


651
TTTATCAATG TCCTTCGGAA GATCTGACCG AAGCCGAAGA AAGCCTGATG


 


701
CGCGAACTGG CGGTTCGCGG CGCGCAGGCA ATCGGTGCGG AAGGCTGCGT


 


751
GCGCGTCGAT TTCCTCAAAG ATACCGACGG CAAACTCTAT CTGTTGGAAA


 


801
TCAACACCCT GCCCGGTATG ACCGGCCATA G






This corresponds to the amino acid sequence <SEQ ID 320; ORF 093.a>:










a093.pep




1
MQNFGKVAVL MGGFSSEREI SLDSGTAILN ALKSKGIDAY AFDPKETPLS


 


51
ELKAQGFQTA FNILHGTYGE DGAVQGALEL LGIPYTGSGV AASAIGMDKY


 


101
RCKLIWQALG LPVPEFAVLH DDTDFDAVEE KLGLPMFVKP AAEGSSVGVV


 


151
KVKGKGRLKS VYEELKHFQX RNHCRTVYRR RRIFLPCVER QRPARHTHHP


 


201
RDRVL*LRSQ VQPQRHHLSM SFGRSDRSRR KPDARTGGSR RAGNRCGRLR


 


251
ARRFPQRYRR QTLSVGNQHP ARYDRP*






m093/a093 95.7% identity over a 276 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 321>:










g094.seq




1
ATGTATTCGC CTTTGCCCAA GCGGGCGTTG GTGCCTGCGG CGTTGAGTTT


 


51
GCCGCCGATA ACGAAAGTGG GGTCGAGTCC TGCCGCGCCG AGGATGGAGG


 


101
CGGTCAGGCT GGTGGTCGTG GTTTTGCCGT GCGTAccggc aatggcgatg


 


151
cCGTCACGGA AGCGCATCAG CTCTGCCAGC ATCAAGGCGC GCGGAATAAC


 


201
GGGAATTTGC CGCTCCAACG CAgcgacaAC TTCGGgattT TCTTTCTTGA


 


251
CGGCGGTAGA GGCAACGACG ACATccgcAC CGTTAACGTG TTCTGCGGTA


 


301
TGGCCGGGAT AA






This corresponds to the amino acid sequence <SEQ ID 322; ORF 094.ng>:










g094.pep




1
MYSPLPKRAL VPAALSLPPI TKVGSSPAAP RMEAVRLVVV VLPCVPAMAM


 


51
PSRKRISSAS IKARGITGIC RSNAATTSGF SFLTAVEATT TSAPLTCSAV


 


101
WPG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 323>:










m094.seq




1
ATGTATTCGC CTTTGCCCAA GCGGGCGTTA GTGCCTGCGG CGTTGAGTTT


 


51
GCCGCCGATA ACGAAAGTCG GGTCAAGTCC TGCCGCGCCG AGGATGGAGG


 


101
CGGTCAGGCT GGTGGTCGTG GTTTTGCCGT GCGTGCCGGC AATGGCGATG


 


151
CCGTCACGGA AGCGCATCAA CTCCGCCAAC ATCAGGGCGC GCGGAATAAC


 


201
GGGAATTTGC TGCTCCAACG CAGCGACAAC TTCGGGATTT TCTTTTTTGA


 


251
CGGCGGTAGA GGTAACGACG ACATCCGCAC CGTTAACGTG TTCGGCGGTA


 


301
TGGCCGGGAT AA






This corresponds to the amino acid sequence <SEQ ID 324; ORF 094>:










m094.pep




1
MYSPLPKRAL VPAALSLPPI TKVGSSPAAP RMEAVRLVVV VLPCVPAMAM


 


51
PSRKRINSAN IRARGITGIC CSNAATTSGF SFLTAVEVTT TSAPLTCSAV


 


101
WPG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 094 shows 95.1% identity over a 103 aa overlap with a predicted ORF (ORF 094.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 325>:










a094.seq




1
ATGTATTCGC CTTTGCCCAA GCGGGCGTTG GTGCCTGCGG CGTTGAGTTT


 


51
GCCGCCGATA ACGAAAGTCG GGTCAAGTCC TGCCGCGCCG AGGATGGAGG


 


101
CGGTCAGGCT GGTGGTCGTG GTTTTGCCGT GCGTGCCGGC AATGGCGATG


 


151
CCGTCACGGA AGCGCATCAA CTCCGCCAAC ATCAGGGCGC GCGGAATAAC


 


201
GGGAATTTGC TGCTCCAACG CAGCGACAAC TTCGGGATTT TCTTTTTTGA


 


251
CGGCGGTAGA GGTAACGACG ACATCCGCAC CGTTAACGTG TTCTGCGGTA


 


301
TGGCCGGGAT AA






This corresponds to the amino acid sequence <SEQ ID 326; ORF 094.a>:










a094.pep




1
MYSPLPKRAL VPAALSLPPI TKVGSSPAAP RMEAVRLVVV VLPCVPAMAM


 


51
PSRKRINSAN IRARGITGIC CSNAATTSGF SFLTAVEVTT TSAPLTCSAV


 


101
WPG*






m094/a094 100.0% identity over a 103 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 327>:










g095.seq




1
ATGTCCTTTC ATTTGAACAT GGACGGTGAA TTTCATTTGC GCGCCGACGT


 


51
TTTCGATGTC GGTGGCGTAG ATGTCGGCGG TATCGTCCAA ACCGTAAGTA


 


101
GCATAAGGTT TGCTCACTTT GGGCAAAATC GCGCGGACGT GTTCGCTGTC


 


151
AACACACAAA AAGGCTTTGC CGTAGAAGGG CATACGGTGG ATGAAATCGA


 


201
TAAACGCCTG ATGCAGTTTT TCGACGCTGT GCCCGTAGGT ATCCATATGG


 


251
TCTTCGTCGA TATTGGTAAC GACGGACATA ATCGGGGTCA GTGTAGGAAA


 


301
GAGGCATCGG ATCGTCGGCT TCGGCAACGA TGTATTCGCC TTTGCCCAAG


 


351
CGGGCGTTGG TGCCTGCGGC GTTGA






This corresponds to the amino acid sequence <SEQ ID 328; ORF 095.ng>:










g095.pep




1
MSFHLNMDGE FHLRADVFDV GGVDVGGIVQ TVSSIRFAHF GQNRADVFAV


 


51
NTQKGFAVEG HTVDEIDKRL MQFFDAVPVG IHMVFVDIGN DGHNRGQCRK


 


101
EASDRRLRQR CIRLCPSGRW CLRR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 329>:










m095.seq




1
ATGTCCTTTC ATTTGAACAT GGACGGTGAA TTTCATTTGC GCGCCGACGT


 


51
TTTCGATGTC GGTGGCGTAG ATGTCGGCGG TATCGTCCAA ACCGTAAGTA


 


101
GCATAAGGTT TGCTCACTTT GGGCAAAATC GCGCGGACGT GTTCGCTGTC


 


151
AATACACAAA AAGGCTTTGC CGTAGAAGGG CATACGGTGG ATGAAATCGA


 


201
TAAACGCCTG ATGCAGTTTT TCGACGCTGT GCCCGTAGGT ATCCATATGG


 


251
TCTTCGTCGA TATTGGTAAC GACGGACATA ATCGGTGTCA GTGCAGAAAG


 


301
GATGCATCCG ACCGTCGGCT TCGGCAACGA TGTATTCGCC TTTGCCCAAG


 


351
CGGGCGTTAG TGCCTGCGGC GTTGA






This corresponds to the amino acid sequence <SEQ ID 330; ORF 095>:










m095.pep




1
MSFHLNMDGE FHLRADVFDV GGVDVGGIVQ TVSSIRFAHF GQNRADVFAV


 


51
NTQKGFAVEG HTVDEIDKRL MQFFDAVPVG IHMVFVDIGN DGHNRCQCRK


 


101
DASDRRLRQR CIRLCPSGRX CLRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 095 shows 97.6% identity over a 124 aa overlap with a predicted ORF (ORF 095.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 331>:










a095.seq




1
ATGTCCTTTC ATTTGAACAT GGACGGTGAA TTTCATTTGC GCGCCGACGT


 


51
TTTCGATGTC GGTGGCGTAG ATGTCGGCGG TATCGTCCAA ACCGTAAGTA


 


101
GCATAAGGTT TGCTCACTTT GGGCAAAATC GCGCGGACGT GTTCGCTGTC


 


151
AATACACAAA AAGGCTTTGC CGTAGAAGGG CATACGGTGG ATGAAATCGA


 


201
TAAACGCCTG ATGCAGCTTC TCAACACTGT GCCCGTAGGT ATCCATATGG


 


251
TCTTCGTCGA TATTGGTAAC GACGGACATA ATCGGTGTCA GTGCAGAAAG


 


301
GATGCATCCG ACCGTCGGCT TCGGCAACGA TGTATTCGCC TTTGCCCAAG


 


351
CGGGCGTTGG TGCCTGCGGC GTTGA






This corresponds to the amino acid sequence <SEQ ID 332; ORF 095.a>:










a095.pep




1
MSFHLNMDGE FHLRADVFDV GGVDVGGIVQ TVSSIRFAHF GQNRADVFAV


 


51
NTQKGFAVEG HTVDEIDKRL MQLLNTVPVG IHMVFVDIGN DGHNRCQCRK


 


101
DASDRRLRQR CIRLCPSGRW CLRR*






m095/a095 96.0% identity in 124 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 333>:










g096.seq




1
ATGGCCGGTC ATACCGGGCA GGGTGTTGAT TTCCAACAGA TAGAGTTTGC


 


51
CGTCGGTATC TTTGAGGAAA TCGACGCGCA CGCAGCCTTC CGCACCGATT


 


101
GCCTGTGCGC CGCGAACCGC CAGTTCGCGC ATCAGGCTTT CTTCGGCTTC


 


151
GGTCAAATCT TCCGAAGGAC ATTGAtaaat ggtgTCGTCT CGGttgtaCt


 


201
tggcttcgta gTCGTAAAAC TCGGTTGCGG GGATGATGTG TATGCCGGGC


 


251
AGCCCTTTGC CGTTCAGGAC GGGGCAGGAA TATTCGCCGC CGCCGATAAA


 


301
AcgtTcggca atgaTTtcgc ccctgAAGGT GttTCAattc ttcgtaAACG


 


351
CTTTTCAGAc ggccttTTTC TTTGA






This corresponds to the amino acid sequence <SEQ ID 334; ORF 096.ng>:










g096.pep




1
MAGHTGQGVD FQQIEFAVGI FEEIDAHAAF RTDCLCAANR QFAHQAFFGF


 


51
GQIFRRTLIN GVVSVVLGFV VVKLGCGDDV YAGQPFAVQD GAGIFAAADK


 


101
TFGNDFAPEG VSILRKRFSD GLFL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 335>:










m096.seq




1
ATGGCTCGTC ATACCGGGCA GGGTGTTGAT TTCCAACAGA TAGAGTTTGC


 


51
CGTCGGTATC TTTGAGGAAA TCGACGCGCA CGCAGCCTTC CGCACCGATT


 


101
GCCTGCGCGC CGCGAACCGC CAGTTCGCGC ATCAGGCTTT CTTCGGCTTC


 


151
GGTCAAATCT TCCGAAGGAC ATTGATAAAT GGTGTCGTCG CGGTTGTACT


 


201
TGGCTTCGTA GTCGTAAAAC TCGGTTGCGG GAATGATGTG TATGCCGGGC


 


251
AGCCCTTTGC CGTTCAGGAC GGGGCAGGAA TATTCGCCGC CGCCGATAAA


 


301
ACGTTCGGCA ATGATTTCGC CC.TGAAGGT GTTTCAATTC TTCGTAAACG


 


351
CTTTTCAGAC GGCCTTTTCC TTTGA






This corresponds to the amino acid sequence <SEQ ID 336; ORF 096>:










m096.pep




1
MARHTGQGVD FQQIEFAVGI FEEIDAHAAF RTDCLRAANR QFAHQAFFGF


 


51
GQIFRRTLIN GVVAVVLGFV VVKLGCGNDV YAGQPFAVQD GAGIFAAADK


 


101
TFGNDFAXEG VSILRKRFSD GLFL*






m096/g096 96.0% identity in 124 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 337>:









a096.seq




1
ATGGCCGGTC ATACCGGGCA GGGTGTTGAT TTCCAACAGA TAGAGTTTGC


 


51
CGTCGGTATC TTTGAGGAAA TCGACGCGCA CGCAGCCTTC CGCACCGATT


 


101
GCCTGCGCGC CGCGAACCGC CAGTTCGCGC ATCAGGCTTT CTTCGGCTTC


 


151
GGTCAGATCT TCCGAAGGAC ATTGATAAAT GGTGTCGTTG CGGTTGTACT


 


201
TGGCTTCGTA GTCATAAAAC TCGGTCGCGG GGATGATGTG TATGCCGGGC


 


251
AGGCCTTTGC CGTTCAACAC AGGGCAGGAA TATTCGCCGC CGCCGATAAA


 


301
CCGTTCGGCA ATGATTTCGC CCT.GAAAGT GTTTCAATTC TTCGTAAACG


 


351
CTTTTCAGAC GGCCTTTTCC TTTGA






This corresponds to the amino acid sequence <SEQ ID 338; ORF 096.ng>:










a096.pep




1
MAGHTGQGVD FQQIEFAVGI FEEIDAHAAF RTDCLRAANR QFAHQAFFGF


 


51
GQIFRRTLIN GVVAVVLGFV VIKLGRGDDV YAGQAFAVQH RAGIFAAADK


 


101
PFGNDFAXES VSILRKRFSD GLFL*






m096/a096 92.7% identity in 124 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 339>:










g097.seq




1
ATGGATATTT CAAAACAAAC ATTGCTGGAT AGGGTTTTTA ACCTGAAGGC


 


51
AAACGGTACG ACGGTACGTA CCGAGTTGAT GGCGGGTTTG ACGACCTTTT


 


101
TGACGATGTG CTACATCGTT ATCGTCAATC CCCTGATTTT GGGCGAGACC


 


151
GGAATGGATA TGGGGGCGGT ATTCGTCGCT ACCTGTATCG CATCCGCCAT


 


201
CGGCTGTTTT GTCATGGGTT TTATCGGCAA CTATCCGATT GCGCTTGCCC


 


251
CGGGGATGGG GCTGAATGCC TATTTCACCT TTGCCGTCGT TAAGGGTATG


 


301
GGCGTGCCTT GGCAGGTGGC GTTGGGTGCG GTGTTCATTT CCGGTCTGAT


 


351
TTTCATCCTG TTCAGCTTTT TTAAAGTCAG GGAAATGCTG GTCAACGCAC


 


401
TGCCTATGGG TTTGAAAATG TCGATTGCCG CCGGTATCGG TTTGTTTTTG


 


451
GCACTGATTT CCCTGAAAGG CGCAGGCATT ATCGTTGCCA ATCCGGCAAC


 


501
CTTGGTCGGC TTGGGCGATA TTCATCAGCC CAGCGCACTG TTGGCATTGT


 


551
TCGGTTTTGT CATGGTGGTC GTATTGGGGT ATTTCCGCGT TCAAGGCGCA


 


601
ATCATCATCA CCATTCTGAC GATTACCGTC ATTGCCAGCC TGATGGGTTT


 


651
GAACGAGTTT CACGGCGTGG TCGGCGAAGT ACCGGGCATT GCGCCGACCT


 


701
TTATGCAGAT GGATTTTAAA GGTCTGTTTA CCGTCAGCAT GGTCAGCGTG


 


751
ATTTTCGTCT TCTTCTTGGT CGATTTGTTC GACAGTACCG GAACGCTGGT


 


801
CGGCGTATCC CACCGTGCCG GACTGCTGGT GGACGGTAAG CTGCCCCGCC


 


851
TGAAACGCGC ACTGCTTGCA GACTCTACCG CCATTGTGGC AGGTGCGGCT


 


901
TTGGGTACTT CTTCAACCAC GCCTTATGTG GAAAGCGCGG CGGGCGTATC


 


951
GGCAGGCGGA CGGACCGGCC TGACGGCGGT TACCGTCGGC GTATTGATGC


 


1001
TGGCGTGTCT GATGTTCTCC CCATTGGCGA AAAGTGTTCC GGTATTTGCC


 


1051
ACCGCGCCCG CACTGCTTTA TGTCGGCACG CAGATGCTCC GCAGTGCGAG


 


1101
GGACATTGAT TGGGACGATA TGACTGAAGC CGCGCCCGCG TTCCTGACCA


 


1151
TTGTCTTCAT GCCGTTTACC TATTCGATTG CAGACGGCAT CGCCTTCGGC


 


1201
TTCATCAGCT ATGCCGTGGT CAAACTTTTG TGTCGCCGGA CTGGGGACGT


 


1251
GCCGCCTATG GTATGGGTTG TTGCCGTATT GTGGGCATTG AAATTCTGGT


 


1301
ATTTGGGCTG A






This corresponds to the amino acid sequence <SEQ ID 340. ORF 097.ng>:










g097.pep




1
MDISKQTLLD RVFNLKANGT TVRTELMAGL TTFLTMCYIV IVNPLILGET


 


51
GMDMGAVFVA TCIASAIGCF VMGFIGNYPI ALAPGMGLNA YFTFAVVKGM


 


101
GVPWQVALGA VFISGLIFIL FSFFKVREML VNALPMGLKM SIAAGIGLFL


 


151
ALISLKGAGI IVANPATLVG LGDIHQPSAL LALFGFVMVV VLGYFRVQGA


 


201
IIITILTITV IASLMGLNEF HGVVGEVPGI APTFMQMDFK GLFTVSMVSV


 


251
IFVFFLVDLF DSTGTLVGVS HRAGLLVDGK LPRLKRALLA DSTAIVAGAA


 


301
LGTSSTTPYV ESAAGVSAGG RTGLTAVTVG VLMLACLMFS PLAKSVPVFA


 


351
TAPALLYVGT QMLRSARDID WDDMTEAAPA FLTIVFMPFT YSIADGIAFG


 


401
FISYAVVKLL CRRTGDVPPM VWVVAVLWAL KFWYLG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 341>:










m097.seq




1
ATGGACACTT CAAAACAAAC ACTGTTGGAC GGGATTTTTA AGCTGAAGGC


 


51
AAACGGTACk ACGGTGCGTA CCGAGTTGAT GGCGGGTTTG ACAACTTTTT


 


101
TGACGATGTG CTACATCGTT ATCGTCAACC CTCyGATTTT GGGCGAGACC


 


151
GGCATGGATA TGGGGGCGGT ATTCGTCGCT ACCTGTATCG CGTCTGCCAT


 


201
CGGCTGTTTT GTTATGGGTT TTGTCGGCAA CTATCCGATT GCACTCGCAC


 


251
CGGGGATGGG GCTGAATGCC TATTTCACCT TTGCCGTCGT TAAGGGTATG


 


301
GGCGTGCCTT GGCAGGTTGC GTTGGGTGCG GTGTTCATCT CCGGTCTGAT


 


351
TTTTATCCTG TTCAGCTTTT TTAAAGTCAG GGAAATGCTG GTCAACGCAC


 


401
TGCCTATGGG TTTGAAAATG TCGATTGCTG CCGGTATCGG TTTGTTTTTG


 


451
GCACTGATTT CCCTGAAAGG CGCAGGCATT ATCGTTGCCA ATCCGGCAAC


 


501
CTTGGTCGGT TTGGGCGATA TTCATCAGCC GTCCGCGTTG TTGGCATTGT


 


551
TCGGTTTTGC TATGGTGGTC GTATTGGGAC ATTTCCGCGT TCAAGGCGCA


 


601
ATCATCATCA CCATCTTGAC CATTACCGTC ATTGCCAGCC TGATGGGTTT


 


651
GAATGAATTT CACGGCATCA TCGGCGAAGT ACCGAGCATT GCGCCGACTT


 


701
TTATGCAGAT GGATTTTGAA GGCCTGTTTA CCGTCAGCAT GGTCAGTGTG


 


751
ATTTTCGTCT TCTTCTTGGT CGATCTATTT GACAGTACCG GAACGCTGGT


 


801
CGGCATATCC CACCGTGCCG GGCTGCTGGT GGACGGTAAG CTGCCCCGCC


 


851
TGAAACGCGC ACTGCTTGCA GACTCTACCG CCATTGTGGC AGGTGCGGCT


 


901
TTGGGTACTT CTTCCACCAC GCCTTATGTG GAAAGCGCGG CGGGCGTATC


 


951
GGCAGGCGGA CGGACCGGCC TGACGGCGGT TACCGTCGGC GTATTGATGC


 


1001
TCGCCTGCCT GATGTTTTCA CCTTTGGCGA AAAGTGTTCC CGCTTTTGCC


 


1051
ACCGCGCCCG CCCTGCTTTA TGTCGGCACG CAGATGCTCC GCAGTGCGAG


 


1101
GGATATTGAT TGGGACGATA TGACGGAAGC CGCACCTGCG TTCCTGACCA


 


1151
TTGTTTTCAT GCCGTTTACT TATTCGATTG CAGACGGCAT CGCTTTCGGC


 


1201
TTCATCAGTT ATGCCGTGGT TAAACTTTTA TGCCGCCGCA CCAAAGACGT


 


1251
TCCGCCTATG GTATGGATTG TTGCCGTATT GTGGGCACTG AAATTCTGGT


 


1301
ATTTGGGCTG A






This corresponds to the amino acid sequence <SEQ ID 342; ORF 097>:










m097.pep




1
MDTSKQTLLD GIFKLKANGT TVRTELMAGL TTFLTMCYIV IVNPXILGET


 


51
GMDMGAVFVA TCIASAIGCF VMGFVGNYPI ALAPGMGLNA YFTFAVVKGM


 


101
GVPWQVALGA VFISGLIFIL FSFFKVREML VNALPMGLKM SIAAGIGLFL


 


151
ALISLKGAGI IVANPATLVG LGDIHQPSAL LALFGFAMVV VLGHFRVQGA


 


201
IIITILTITV IASLMGLNEF HGIIGEVPSI APTFMQMDFE GLFTVSMVSV


 


251
IFVFFLVDLF DSTGTLVGIS HRAGLLVDGK LPRLKRALLA DSTAIVAGAA


 


301
LGTSSTTPYV ESAAGVSAGG RTGLTAVTVG VLMLACLMFS PLAKSVPAFA


 


351
TAPALLYVGT QMLRSARDID WDDMTEAAPA FLTIVFMPFT YSIADGIAFG


 


401
FISYAVVKLL CRRTKDVPPM VWIVAVLWAL KFWYLG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 097 shows 96.3% identity over a 436 aa overlap with a predicted ORF (ORF 097.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 343>










a097.seq




1
ATGGACACTT CAAAACAAAC ACTGTTGGAC GGGATTTTTA AGCTGAAGGC


 


51
AAACGGTACG ACGGTGCGTA CCGAGTTGAT GGCGGGTTTG ACAACTTTTT


 


101
TGACGATGTG CTACATCGTT ATCGTCAACC CTCTGATTTT GGGCGAGACC


 


151
GGCATGGATA TGGGGGCGGT ATTCGTCGCT ACCTGTATCG CGTCTGCCAT


 


201
CGGCTGTTTT GTTATGGGTT TTGTCGGCAA CTATCCGATT GCACTCGCAC


 


251
CGGGGATGGG GCTGAATGCC TATTTCACCT TTGCCGTCGT TAAGGGTATG


 


301
GGCGTGCCTT GGCAGGTTGC GTTGGGTGCG GTGTTCATCT CCGGTCTGAT


 


351
TTTCATCCTG TTCAGCTTTT TTAAAGTCAG GGAAATGCTG GTCAACGCAC


 


401
TGCCTATGGG TTTGAAAATG TCGATTGCTG CCGGTATCGG TTTGTTTTTG


 


451
GCACTGATTT CCCTGAAAGG CGCAGGCATT ATCGTTGCCA ATCCGGCAAC


 


501
CTTGGTCGGC TTGGGCGATA TTCATCAGCC GTCCGCGTTG TTGGCACTGT


 


551
TCGGTTTTGC CATGGTGGTC GTATTGGGAC ATTTCCGCGT TCAAGGCGCA


 


601
ATCATCATCA CCATTTTGAC GATTACCGTC ATTGCCAGCC TGATGGGTTT


 


651
GAACGAATTT CACGGCATCA TCGGCGAAGT GCCGAGCATT GCGCCGACTT


 


701
TTATGCAGAT GGATTTTAAA GGGTTGTTTA CCGTCAGCAT GGTCAGCGTG


 


751
ATTTTCGTCT TTTTCCTAGT CGATCTGTTC GACAGTACCG GAACACTGGT


 


801
CGGTGTATCG CATCGTGCCG GACTGCTGGT GGACGGTAAG CTGCCCCGCC


 


851
TGAAACGCGC ACTGCTTGCA GACTCTACCG CTATTGTGGC AGGTGCGGCT


 


901
TTGGGTACTT CTTCAACCAC GCCTTATGTG GAAAGTGCGG CGGGCGTATC


 


951
GGCAGGCGGG CGGACAGGTC TGACGGCGGT TACCGTCGGC GTATTGATGC


 


1001
TCGCCTGCCT GATGTTTTCA CCTTTGGCGA AAAGTGTTCC CGCTTTTGCC


 


1051
ACCGCGCCCG CCCTGCTTTA TGTCGGCACG CAGATGCTCC GCAGTGCGAG


 


1101
GGACATCGAT TGGGACGATA TGACGGAAGC CGCACCCGCA TTCCTGACCA


 


1151
TTGTCTTCAT GCCGTTTACC TATTCGATTG CAGACGGCAT CGCTTTCGGC


 


1201
TTCATCAGTT ATGCCGTGGT TAAACTTTTA TGCCGCCGCA CCAAAGACGT


 


1251
TCCGCCTATG GTATGGATTG TTGCCGTATT GTGGGCACTG AAATTCTGGT


 


1301
ATTTGGGCTG A






This corresponds to the amino acid sequence <SEQ ID 344; ORF 097.a>:










a097.pep




1
MDTSKQTLLD GIFKLKANGT TVRTELMAGL TTFLTMCYIV IVNPLILGET


 


51
GMDMGAVFVA TCIASAIGCF VMGFVGNYPI ALAPGMGLNA YFTFAVVKGM


 


101
GVPWQVALGA VFISGLIFIL FSFFKVREML VNALPMGLKM SIAAGIGLFL


 


151
ALISLKGAGI IVANPATLVG LGDIHQPSAL LALFGFAMVV VLGHFRVQGA


 


201
IIITILTITV IASLMGLNEF HGIIGEVPSI APTFMQMDFK GLFTVSMVSV


 


251
IFVFFLVDLF DSTGTLVGVS HRAGLLVDGK LPRLKRALLA DSTAIVAGAA


 


301
LGTSSTTPYV ESAAGVSAGG RTGLTAVTVG VLMLACLMFS PLAKSVPAFA


 


351
TAPALLYVGT QMLRSARDID WDDMTEAAPA FLTIVFMPFT YSIADGIAFG


 


401
FISYAVVKLL CRRTKDVPPM VWIVAVLWAL KFWYLG*






m097/a097 99.3% identity in 436 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 345>:










g098.seq




1
ATGACCGCCG ACGGTCTCTT CGTCGCTTTC AACTTCAATA CGTTTGCCGT


 


51
TGTGCGAATA TTGATACCAG TACAGCAGGA TGCTGCCCAG GCTGGCGATC


 


101
AGTTTGTCGG CGATGTCGCG CGCTTCGCTG TCGGGATGGC TTTCGCGTTC


 


151
GGGATGAACG CAGCCGAGCA TGGACACGCC GGTACGCATC ACGTCCATCG


 


201
GATGGGTATG TGCAGGCAGG CTTTCCAAAA CTTTAATCAC ACGGATAGGC


 


251
AGGCCGCGCA TGGATTTGAG CTTGGTTTTA TAAGCGGCCA GCTCGAATTT


 


301
GTTGGGCAGA TGGCCGTGAA TCAGCAAGTG TGCGACTTCT TCAAACTCGC


 


351
ATTTTTGTGC CAAATTAGAA TGTCGTAA






This corresponds to the amino acid sequence <SEQ ID 346; ORF 098.ng>:










g098.pep




1
MTADGLFVAF NFNTFAVVRI LIPVQQDAAQ AGDQFVGDVA RFAVGMAFAF


 


51
GMNAAEHGHA GTHHVHRMGM CRQAFQNFNH TDRQAAHGFE LGFISGQLEF


 


101
VGQMAVNQQV CDFFKLAFLC QIRMS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 347>:










m098.seq




1
ATGACCGCCG ATGGTCTCTT CGTCGCTTTC AACCTCAATG CGTTTGCCGT


 


51
TGTGCGAATA TTGATACCAG TACAAGAGGA TGCTGCCGAG GCTGGCGATC


 


101
AGTTTGTCGG CGATGTCGCG CGCTTCACTT TCCGGATGGC TTTCACGTTC


 


151
AGGATGAACG CAGCCCAGCA TGGATACGCC GGTACGCATT ACGTCCATCG


 


201
GATGGGTATG TGCAGGCAGG CTTTCCAAAA CTTTAATCAC ACGGATAGGC


 


251
AGGCCGCGCA TGGATTTGAG CTTGGTTTTA TAAGCGGCCA GCTCGAATTT


 


301
GTTGGGCAGA TGGCCGTGAA TCAGCAGGTG GGCGACTTCT TCAAACTCGC


 


351
ATTTTTGTGC CAAATCAGAA TGTCGTAA






This corresponds to the amino acid sequence <SEQ ID 348; ORF 098>:










m098.pep




1
MTADGLFVAF NLNAFAVVRI LIPVQEDAAE AGDQFVGDVA RFTFRMAFTF


 


51
RMNAAQHGYA GTHYVHRMGM CRQAFQNFNH TDRQAAHGFE LGFISGQLEF


 


101
VGQMAVNQQV GDFFKLAFLC QIRMS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 098 shows 89.6% identity over a 125 aa overlap with a predicted ORF (ORF 098.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 349>:










a098.seq




1
ATGACCGCCG ATGGTCTCTT CGTCGCTTTC AACCTCAATG CGTTTGCCGT


 


51
TGTGCGAATA TTGATACCAG TACAAGAGGA TGCTGCCGAG GCTGGCGATC


 


101
AGTTTGTCGG CGATGTCGCG CGCTTCACTT TCCGGATGGC TTTCACGTTC


 


151
AGGATGAACG CAGCCCAGCA TGGATACGCC GGTACGCATT ACGTCCATCG


 


201
GATGGGTATG TGCAGGCAGG CTTTCCAAAA CTTTAATCAC ACGGATAGGC


 


251
AGGCCGCGCA TGGATTTGAG CTTGGTTTTA TAAGCGGCCA GCTCGAATTT


 


301
GTTGGGCAGA TGGCCGTGAA TCAGCAGGTG GGCGACTTCT TCAAACTCGC


 


351
ATTTTTGTGC CAAATCAGAA TGTCGTAA






This corresponds to the amino acid sequence <SEQ ID 350; ORF 098.a>:










a098.pep




1
MTADGLFVAF NLNAFAVVRI LIPVQEDAAE AGDQFVGDVA RFTFRMAFTF


 


51
RMNAAQHGYA GTHYVHRMGM CRQAFQNFNH TDRQAAHGFE LGFISGQLEF


 


101
VGQMAVNQQV GDFFKLAFLC QIRMS*






m098/a098 100.0% identity in 125 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 351>:










g099.seq




1
ATGCTGGGAC GCGCGTCCAT GATGCGCCTG CCCGATATTG TCGGCGTGGA


 


51
GCTGACGGGC AAACGGCAGG CGGGCATTAC TGCCACAGAC ATCGTGTTGG


 


101
CACTGACCGA ATTCTTGCGT AAAGAGCGCG TGGTCGGGGC GTTTGTCGAA


 


151
TTTTTCGGCG AGGGCGCGAG AAGCCTGTCT ATCGGCGACC GCGCGACCAT


 


201
TTCCAACATG ACGCCGGAGT TCGGCGCGAC TGCCGCCATG TTCGCCATCG


 


251
ACGCGCAAAC TATTGATTAT TTGAAACTGA CCGGACGTGA CGACGCGCAG


 


301
GTGAAATTGG TGGAAACCTA CGCCAAAACC GCAGGCTTAT GGGCAGGTGG


 


351
CTTGAAAACC GCCGTTTATC CGCGCGTTTT GAAATTTGAT TTGAGCAGCG


 


401
TAACGCGCAA TATGGCAGGC CCGAGCAACC CGCACGCGCG TTTTGCCACC


 


451
GCCGATTTGG CGGCGAAAGG GCTGGCGAAG CCTTACGAAG AGCCTTCAGA


 


501
CGGCCAAATG CCTGACGGTG CAGTGATTAT TGCCGCGATT ACTTCGTGTA


 


551
CCAATACTTC CAACCCGCGC AACGTTGTCG CCGCCGCACT GTTGGCACGC


 


601
AATGCCAACC GCCTCGGCTT GAAACGCAAA CCTTGGGTGA AATCTTCGTT


 


651
TGCCCCGGGT TCAAAAGTAG CCGGAATCTA TTTGAAAGAA GCAGGCTTGT


 


701
TGCCCGAAAT GGAAAAACTC GGCTTCGGTA TCGTCGCCTT CGCATGTACC


 


751
ACCTGTAACG GCATGAgcgG CGCGCTcgaC CCGAAAATCC AACAAGAAAT


 


801
CATCGACCGC GAtttgtacg cCACCGCCGT ATTGTCAGGC AACCGCAACT


 


851
TCGACGGCCG TATCCATCCG TATGCGAAAC AGGCTTTCCT CGCTTCGCCT


 


901
CCTTTGGTCG TTGCCTACGC ATTGGCAGGT AGCATCCGTT TCGATATTGA


 


951
AAACGACGTA CTCGGCGTTG CAGACGGCCG CGAAATCCGC CTGAAAGATA


 


1001
TCTGGCCGAC AGACGAAGAA ATCGATGCCA TCGTTGCCGA ATATGTGAAA


 


1051
CCGCAACAAT TCCGCGACAT TTATATCCCG ATGTCCGACA CCGGCACAGC


 


1101
GCAAAAAGCA CCAAGCCCGC TGTACGACTG GCGACCGATG TCCACCTACA


 


1151
TCCGCCGTCC GCCCTATTGG GAAGGCGCAC TGGCAGGGGA ACGTACATTA


 


1201
AGAGGTATGC GTCCGCCGGC GATTTTGCCC GACAACATCA CCACCGACCA


 


1251
CATCTCgcca tCCAATGCGA TTTTGGCCGG cagTGCcgca ggtgaATATT


 


1301
TGGCGAAAAT GGGTTTGCCT GAAGAagaCT TCAACTCTTA CGCAACCCAC


 


1351
CGCGGCGACC ACTTGACCGC CCAACGCGCA ACCTTCGCCA ATCCGAAACT


 


1401
GTTTAACGAA ATGGTGAGAA ACGAAGACGG CAGCGTACGC CAAGGTtcgt


 


1451
tggcacgcgT tgaacCAGAA GGCCAAACCA TGCGCATGTG GGAAGCCATC


 


1501
GAAACCTATA TGAACCGCAA ACAGCCGCTT ATCATCATTG CCGGTGCGGA


 


1551
CTATGGTCAA GGCTCAAGCC GCGACTGGGC GGCGAAGGGC GTGCGGCTGG


 


1601
CGGGTGTGGA AGCCATCGCC GCCGAAGGTT TCGAGCGCAT CCACCGCACC


 


1651
AACCTCATCG GCATGGGCGT CTTGCCGCTG CAATTCAAAC CCGGCACCAA


 


1701
CCGCCATACC CTGCAACTGG ACGGTACGGA AACCTACGAC GTTGTCGGCG


 


1751
AACGCACACC GCGCTGCGGC CTGACCCTCG TGATTCACCG TAAAAACGGA


 


1801
GAAACCGTCG AAGTTCCGGT TACCTGCCGC CCCGATACCG CAGAAGAAGC


 


1851
ATTGGTATAT GAAGCCGGCG GCGTATTGCA ACGGTTTGCA CAGGACTTTT


 


1901
TGGAAGGGAA CGCGGCTTAG






This corresponds to the amino acid sequence <SEQ ID 352; ORF 099.ng>:










g099.pep




1
MLGRASMMRL PDIVGVELTG KRQAGITATD IVLALTEFLR KERVVGAFVE


 


51
FFGEGARSLS IGDRATISNM TPEFGATAAM FAIDAQTIDY LKLTGRDDAQ


 


101
VKLVETYAKT AGLWAGGLKT AVYPRVLKFD LSSVTRNMAG PSNPHARFAT


 


151
ADLAAKGLAK PYEEPSDGQM PDGAVIIAAI TSCTNTSNPR NVVAAALLAR


 


201
NANRLGLKRK PWVKSSFAPG SKVAGIYLKE AGLLPEMEKL GFGIVAFACT


 


251
TCNGMSGALD PKIQQEIIDR DLYATAVLSG NRNFDGRIHP YAKQAFLASP


 


301
PLVVAYALAG SIRFDIENDV LGVADGREIR LKDIWPTDEE IDAIVAEYVK


 


351
PQQFRDIYIP MSDTGTAQKA PSPLYDWRPM STYIRRPPYW EGALAGERTL


 


401
RGMRPPAILP DNITTDHISP SNAILAGSAA GEYLAKMGLP EEDFNSYATH


 


451
RGDHLTAQRA TFANPKLFNE MVRNEDGSVR QGSLARVEPE GQTMRMWEAI


 


501
ETYMNRKQPL IIIAGADYGQ GSSRDWAAKG VRLAGVEAIA AEGFERIHRT


 


551
NLIGMGVLPL QFKPGTNRHT LQLDGTETYD VVGERTPRCG LTLVIHRKNG


 


601
ETVEVPVTCR PDTAEEALVY EAGGVLQRFA QDFLEGNAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 353>:










m099.seq




1
ATGCTGGGAC GCGCGTCCAT GATGCGCCTG CCCGATATTG TCGGCGTTGA


 


51
GCTGAACGGC AAACGGCAGG CGGGCATTAC GGCGACGGAT ATTGTGTTGG


 


101
CACTGACCGA GTTTCTGCGC AAAGAACGCG TGGTCGGGGC GTTTGTCGAA


 


151
TTCTTCGGCG AGGGCGCGAG AAGCCTGTCT ATCGGCGACC GCGCGACCAT


 


201
TTCCAACATG ACGCCGGAGT TCGGCGCGAC TGCCGCGATG TTCGCTATTG


 


251
ATGAGCAAAC CATTGATTAT TTGAAACTGA CCGGACGCGA CGACGCGCAG


 


301
GTGAAATTGG TGGAAACCTA CGCCAAAACC GCAGGCTTGT GGGCAGATGC


 


351
CTTGAAAACC GCCGTTTATC CTCGCGTTTT GAAATTTGAT TTGAGCAGCG


 


401
TAACGCGCAA TATGGCAGGC CCAAGTAACC CGCATGCCCG TTTTGCGACC


 


451
GCCGATTTGG CGGCGAAAGG GCTGGCGAAG CCTTACGAAG AGCCTTCGGA


 


501
CGGCCAAATG CCCGACGGCT CGGTCATCAT CGCCGCGATT ACCAGTTGCA


 


551
CCAACACTTC CAACCCGCGC AACGTTGTTG CCGCCGCGCT CTTGGCACGC


 


601
AATGCCAACC GTCTCGGCTT GAAACGCAAA CCTTGGGTGA AATCTTCGTT


 


651
TGCCCCGGGT TCAAAAGTAG CCGAAATCTA TTTGAAAGAA GCGGGCCTGT


 


701
TGCCCGAAAT GGAAAAACTC GGCTTCGGTA TCGTCGCCTT CGCCTGCACC


 


751
ACCTGCAACG GCATGAGTGG CGCGCTGGAT CCGAAAATCC AGAAAGAAAT


 


801
CATCGACCGC GATTTGTACG CCACCGCCGT ATTATCAGGC AACCGCAACT


 


851
TCGACGGCCG TATCCACCCG TATGCGAAAC AGGCTTTCCT CGCTTCGCCT


 


901
CCGTTGGTCG TTGCCTACGC GCTGGCAGGC AGTATCCGTT TCGATATTGA


 


951
AAACGACGTA CTCGGCGTTG CAGACGGCAA GGAAATCCGC CTGAAAGACA


 


1001
TTTGGCCTGC CGATGAAGAA ATCGATGCCG TCGTTGCCGA ATATGTGAAA


 


1051
CCGCAGCAGT TCCGCGATGT GTATGTACCG ATGTTCGACA CCGGCACAGC


 


1101
GCAAAAAGCA CCCAGTCCGC TGTACGATTG GCGTCCGATG TCCACCTACA


 


1151
TCCGCCGTCC GCCTTACTGG GAAGGCGCGC TGGCAGGGGA ACGCACATTA


 


1201
AGAGGTATGC GTCCGCTGGC GATTTTGCCC GACAACATCA CCACCGACCA


 


1251
CCTCTCGCCG TCCAATGCGA TTTTGGCCGT CAGTGCCGCA GGCGAGTATT


 


1301
TGGCGAAAAT GGGTTTGCCT GAAGAAGACT TCAACTCTTA CGCAACCCAC


 


1351
CGCGGCGACC ACTTGACCGC CCAACGCGCT ACCTTCGCCA ATCCGAAACT


 


1401
GTTTAACGAA ATGGTGAAAA ACGAAGACGG CAGCGTGCGC CAAGGCTCGT


 


1451
TCGCCCGCGT CGAACCCGAA GGCGAAACCA TGCGCATGTG GGAAGCCATC


 


1501
GAAACCTATA TGAACCGCAA ACAGCCGCTC ATCATCATTG CCGGTGCGGA


 


1551
CTATGGTCAA GGCTCAAGCC GCGACTGGGC TGCAAAAGGC GTACGCCTCG


 


1601
CCGGCGTAGA AGCGATTGTT GCCGAAGGCT TCGAGCGTAT CCACCGCACC


 


1651
AACCTTATCG GCATGGGCGT GTTGCCGCTG CAGTTCAAAC CCGACACCAA


 


1701
CCGCCATACC CTGCAACTGG ACGGTACGGA AACCTACGAC GTGGTCGGCG


 


1751
AACGCACACC GCGCTGCGAC CTGACCCTCG TGATTCACCG TAAAAACGGC


 


1801
GAAACCGTTG AAGTTCCCGT TACCTGCTGC CTCGATACTG CAGAAGAAGT


 


1851
ATTGGTATAT GAAGCCGGCG GCGTGTTGCA ACGGTTTGCA CAGGATTTTT


 


1901
TGGAAGGGAA CGCGGCTTAG






This corresponds to the amino acid sequence <SEQ ID 354; ORF 099>:










m099.pep




1
MLGRASMMRL PDIVGVELNG KRQAGITATD IVLALTEFLR KERVVGAFVE


 


51
FFGEGARSLS IGDRATISNM TPEFGATAAM FAIDEQTIDY LKLTGRDDAQ


 


101
VKLVETYAKT AGLWADALKT AVYPRVLKFD LSSVTRNMAG PSNPHARFAT


 


151
ADLAAKGLAK PYEEPSDGQM PDGSVIIAAI TSCTNTSNPR NVVAAALLAR


 


201
NANRLGLKRK PWVKSSFAPG SKVAEIYLKE AGLLPEMEKL GFGIVAFACT


 


251
TCNGMSGALD PKIQKEIIDR DLYATAVLSG NRNFDGRIHP YAKQAFLASP


 


301
PLVVAYALAG SIRFDIENDV LGVADGKEIR LKDIWPADEE IDAVVAEYVK


 


351
PQQFRDVYVP MFDTGTAQKA PSPLYDWRPM STYIRRPPYW EGALAGERTL


 


401
RGMRPLAILP DNITTDHLSP SNAILAVSAA GEYLAKMGLP EEDFNSYATH


 


451
RGDHLTAQRA TFANPKLFNE MVKNEDGSVR QGSFARVEPE GETMRMWEAI


 


501
ETYMNRKQPL IIIAGADYGQ GSSRDWAAKG VRLAGVEAIV AEGFERIHRT


 


551
NLIGMGVLPL QFKPDTNRHT LQLDGTETYD VVGERTPRCD LTLVIHRKNG


 


601
ETVEVPVTCC LDTAEEVLVY EAGGVLQRFA QDFLEGNAA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 099 shows 96.2% identity over a 639 aa overlap with a predicted ORF (ORF 099.ng) from N. gonorrhoeae:








The following partial DNA sequence was identified in N. meningitidis <SEQ ID 355>:










a099.seq




1
ATGCTGGGAC GCGCGTCCAT GATGCGCCTG CCCGATATTG TCGGCGTTGA


 


51
GCTGAACGGC AAACGGAAGG CGGGCATTAC GGCGACGGAT ATTGTGTTGG


 


101
CACTGACCGA GTTTCTGCGC AAAGAACGCG TGGTCGGGGC GTTTGTCGAA


 


151
TTCTTCGGCG AGGGCGCGAG AAGCCTGTCT ATCGGCGACC GCGCGACCAT


 


201
TTCCAACATG ACGCCGGAGT TCGGCGCGAC TGCCGCGATG TTCGCTATTG


 


251
ATGAGCAAAC CATTGATTAT TTGAAACTGA CCGGACGCGA CGACGCGCAG


 


301
GTGAAATTGG TGGAAACCTA CGCCAAAACC GCAGGCTTGT GGGCAGATGC


 


351
CTTGAAAACC GCCGTTTATC CGCGCGTTTT GAAATTTGAT TTGAGCAGCG


 


401
TAACGCGCAA TATGGCAGGC CCGAGCAACC CGCACGCGCG TTTTGCGACC


 


451
GCCGATTTGG CCGGCAAAGG CTTGGCTAAA CCTTACGAAG AGCCTTCAGA


 


501
CGGCCAAATG CCTGACGGTG CAGTGATTAT TGCCGCGATT ACTTCCTGTA


 


551
CCAATACTTC CAATCCGCGC AACGTTGTCG CCGCCGCGCT GTTGGCACGC


 


601
AATGCCAACC GCCTCGGCTT GCAACGCAAA CCTTGGGTGA AATCTTCGTT


 


651
TGCCCCGGGT TCAAAAGTAG CCGAAATCTA TTTGAAAGAA GCAGATCTGC


 


701
TGCCCGAAAT GGAAAAACTC GGCTTCGGTA TCGTTGCCTT CGCATGTACC


 


751
ACCTGTAACG GCATGAGCGG CGCGCTGGAT CCGAAAATCC AGAAAGAAAT


 


801
CATCGACCGC GATTTGTACG CCACCGCCGT ATTGTCAGGC AACCGCAACT


 


851
TTGACGGCCG TATCCATCCG TATGCGAAAC AGGCTTTCCT CGCTTCGCCT


 


901
CCGTTGGTCG TTGCCTACGC GCTGGCAGGC AGCATCCGTT TCGATATTGA


 


951
AAACGACGTA CTCGGCGTTG CAGACGGCAA AGAAATCCGC CTGAAAGACA


 


1001
TTTGGCCTAC CGATGAAGAA ATCGATGCCA TCGTTGCCGA ATATGTGAAA


 


1051
CCGCAGCAAT TTCGCGACGT TTATATCCCG ATGTTCGACA CCGGCACAGC


 


1101
GCAAAAAGCA CCAAGCCCGC TGTACGACTG GCGTCCAATG TCTACCTATA


 


1151
TCCGCCGCCC ACCTTACTGG GAAGGCGCAC TGGCAGGGGA ACGCACATTA


 


1201
AGCGGTATGC GTCCGCTGGC GATTTTGCCC GACAACATCA CCACCGACCA


 


1251
TCTCTCGCCA TCCAATGCGA TTTTGGCAAG CAGTGCCGCA GGCGAATATT


 


1301
TGGCAAAAAT GGGTTTGCCT GAAGAAGACT TCAACTCTTA CGCAACCCAC


 


1351
CGTGGCGACC ACTTGACCGC CCAACGCGCA ACCTTCGCCA ATCCGAAACT


 


1401
GTTTAACGAA ATGGTGAGAA ACGAAGACGG CAGCGTACGC CAAGGTTCGC


 


1451
TGGCACGCGT TGAACCCGAA GGCCAAACCA TGCGCATGTG GGAAGCCATC


 


1501
GAAACCTATA TGAACCGCAA ACAGCCGCTC ATCATCATTG CCGGCGCGGA


 


1551
CTACGGTCAA GGCTCAAGCC GCGACTGGGC TGCAAAAGGC GTACGCCTCG


 


1601
CCGGCGTGGA AGCGATTGTT GCCGAAGGCT TCGAGCGTAT CCACCGCACC


 


1651
AACTTGATCG GTATGGGCGT GTTGCCGCTG CAGTTCAAAC CGGGTACCAA


 


1701
CCGCCACACC CTGCAACTGG ACGGTACGGA AACCTACGAC GTTGTCGGCG


 


1751
AACGCACACC GCGCTGCGAC CTGACCCTTG TGATTCACCG TAAAAACGGC


 


1801
GAGACCGTCG AAGTCCCCAT TACCTGCCGC CTCGATACCG CAGAAGAAGT


 


1851
GTTGGTATAT GAAGCCGGTG GCGTATTGCA ACGGTTTGCA CAGGATTTTT


 


1901
TGGAAGGGAA CGCGGCTTAG






This corresponds to the amino acid sequence <SEQ ID 356; ORF 099.a>:










a099.pep




1
MLGRASMMRL PDIVGVELNG KRKAGITATD IVLALTEFLR KERVVGAFVE


 


51
FFGEGARSLS IGDRATISNM TPEFGATAAM FAIDEQTIDY LKLTGRDDAQ


 


101
VKLVETYAKT AGLWADALKT AVYPRVLKFD LSSVTRNMAG PSNPHARFAT


 


151
ADLAGKGLAK PYEEPSDGQM PDGAVIIAAI TSCTNTSNPR NVVAAALLAR


 


201
NANRLGLQRK PWVKSSFAPG SKVAEIYLKE ADLLPEMEKL GFGIVAFACT


 


251
TCNGMSGALD PKIQKEIIDR DLYATAVLSG NRNFDGRIHP YAKQAFLASP


 


301
PLVVAYALAG SIRFDIENDV LGVADGKEIR LKDIWPTDEE IDAIVAEYVK


 


351
PQQFRDVYIP MFDTGTAQKA PSPLYDWRPM STYIRRPPYW EGALAGERTL


 


401
SGMRPLAILP DNITTDHLSP SNAILASSAA GEYLAKMGLP EEDFNSYATH


 


451
RGDHLTAQRA TFANPKLFNE MVRNEDGSVR QGSLARVEPE GQTMRMWEAI


 


501
ETYMNRKQPL IIIAGADYGQ GSSRDWAAKG VRLAGVEAIV AEGFERIHRT


 


551
NLIGMGVLPL QFKPGTNRHT LQLDGTETYD VVGERTPRCD LTLVIHRKNG


 


601
ETVEVPITCR LDTAEEVLVY EAGGVLQRFA QDFLEGNAA*






m099/a099 97.5% identity in 639 aa overlap








The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 357>:










g102.seq




1
AtgtCCGCCA AAactccgtc gctcttcggc ggcgcgatga Ttatcgccgg


 


51
gaaggttatc ggcgcAGgta tgttccccaa ccccaccgcc aacttggggg


 


101
acgggttaat aggctcgctg attgtgctgc tgtacacctg gtttccattc


 


151
tcctccggcg ccctcatgat tttggaagtc aacacccata acCCccgagg


 


201
ggcaAGtttt gacaccATGg tcAAagacct gctcgGaCGc ggctggaaca


 


251
tcatcaacgg catcgccgtc gctttggTCc tatacggctc gacctacgcg


 


301
tacattttag tcggcggtga cctGACCGCC AAAGGCAtcg GCAgCGCAGT


 


351
AGGCGGCAAA ATTTCgctca CCGTCGGACA actcgtcttc tTCGGCATCC


 


401
TCGCCTTTTG CGTATGGGCA TCCGCACGCT TGGTCGACCG CTTTACCGGC


 


451
GTCCTCATCG GCGGCATGGT ATTAACCTTT ATTTGGGCAA CCGGCGGCCT


 


501
GGTTGCCGAT GCCAAACCGT CCGTCCTCTT CGACACCCAA GCCCCCGTCG


 


551
GCACCGGCTA CTGGATTTAC GCCGCCACCG CCCTGCCCGT CTGCCTCGCT


 


601
TCCTTCGGCT TCCACGGCAA CGTTTCCAGC CTGCTCAAAT ACTTTAAAGG


 


651
CGACGcgcCc aaagtGgCGA aATCcatctg gGcaggtaca ttggTTGCCt


 


701
tggtaattta cgtccTCTgg caaaccgcca tCcaaagcaa ccTGCcgcgc


 


751
aacgagttcg cCCCcgtgat tgccgccgag aggcaactCT CCGTCCTgaa


 


801
tgaaacccTG tccaaattcg cccaaaccgg cgatatggat aAaatattgt


 


851
ccctatttcc ctacatggca atcgccacct cctttttagg cgTAACctta


 


901
ggcctgtttg acaacatcgc cgacatcttc aaatggaacg acagtatgtc


 


951
cgggcggggc accaaaaccg tcgcgctgaa cttcctgccg CCCCtgattt


 


1001
cctggctgct cctccccacc ggcttcttta ccgccattgg tgcgtccggc


 


1051
ctggcggcaa ccgtctggga ccaagGcatc atccccgcca tgctgctcta


 


1101
cgtttccccc caaaaaattG gcGcaggcaa gacttataAa gtttaCGGCG


 


1151
gcttgtggct gatgttagtc ttccttttcg gcatcgccaa catcgccgca


 


1201
CAGGTATTGA GccaAatgGa ACtcgtCccc GTATTTAAAG GATAA






This corresponds to the amino acid sequence <SEQ ID 358; ORF 102.ng>:










g102.pep




1
MSAKTPSLFG GAMIIAGKVI GAGMFPNPTA NLGDGLIGSL IVLLYTWFPF


 


51
SSGALMILEV NTHNPRGASF DTMVKDLLGR GWNIINGIAV ALVLYGSTYA


 


101
YILVGGDLTA KGIGSAVGGK ISLTVGQLVF FGILAFCVWA SARLVDRFTG


 


151
VLIGGMVLTF IWATGGLVAD AKPSVLFDTQ APVGTGYWIY AATALPVCLA


 


201
SFGFHGNVSS LLKYFKGDAP KVAKSIWAGT LVALVIYVLW QTAIQSNLPR


 


251
NEFAPVIAAE RQLSVLNETL SKFAQTGDMD KILSLFPYMA IATSFLGVTL


 


301
GLFDNIADIF KWNDSMSGRG TKTVALNFLP PLISWLLLPT GFFTAIGASG


 


351
LAATVWDQGI IPAMLLYVSP QKIGAGKTYK VYGGLWLMLV FLFGIANIAA


 


401
QVLSQMELVP VFKG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 359>:










m102.seq




1
ATGCCCAACA AAACCCCTTC ACTGTTCGGC GGCGCGATGA TTATCGCCGG


 


51
CACGGTCATC GGCGCAGGCA TGCTCGCCAA CCCGACCGCC ACATCCGGCG


 


101
TATGGTTTAC CGGCTCGCTG GCCGTGTTGC TGTACACCTG GTTTTCTATG


 


151
CTTTCCAGCG GCCTGATGAT TTTGGAAGTC AACACCCATT ATCCGCACGG


 


201
CGCAAGTTTC GACACGATGG TCAAAGACCT GCTCGGACGC GGCTGGAACA


 


251
TCATCAACGG CATCGCCGTC GCCTTCGTTT TATACCTGCT TACTTACGCT


 


301
TATATCTTCG TCGGCGGCGA CCTGACCGCC AAAGGCTTAG GCAGCGCGGC


 


351
AGGCGGCGAC GTTTCACTCA CCGTCGGACA ACTCGTCTTC TTCGGCATCC


 


401
TCGCCTTTTG CGTATGGGCA TCCGCACGCT TGGTCGACCG CTTCACCGGC


 


451
GTCCTTATCG GCGGCATGGT ATTGACCTTT ATTTGGGCGG CCGGCGGGCT


 


501
GATTGCCGAT GCCAAGCCGT CCGTCCTCTT CGATACCCAA GCCCCCGCCG


 


551
GCACAAACTA CTGGATTTAC GCCGCCACCG CCCTGCCCGT CTGCCTCGCT


 


601
TCCTTCGGCT TCCACGGCAA CGTCTCCAGC CTGCTCAAAT ACTTTAAAGG


 


651
CGACGCGCCC AAAGTGGCTA AATCCATCTG GACGGGCACA CTGATTGCGC


 


701
TGGTAATTTA CGTCCTCTGG CAAACCGCCA TCCAAGGCAA CCTGCCGCGC


 


751
AACGAGTTCG CCCCCGTCAT CGCCGCCGAA GGGCAAGTCT CCGTCCTCAT


 


801
CGAAACCCTG TCCAAATTCG CCCAAACCGG CAATATGGAC AAAATATTGT


 


851
CCCTGTTTTC CTATATGGCG ATCGCCACCT CGTTTTTAGG CGTAACGCTC


 


901
GGACTCTTCG ACTACATCGC CGACATCTTC AAATGGAACG ACAGCATCTC


 


951
CGGCCGCACC AAAACCGCCG CGCTGACCTT CCTGCCGCCC CTGATTTCCT


 


1001
GCCTGCTCTT CCCCACCGGC TTCGTTACCG CCATCGGCTA CGTCGGCCTG


 


1051
GCGGCAACCG TCTGGACAGG CATCATCCCC GCCATGCTGC TCTACCGTTC


 


1101
GCGCAAAAAA TTCGGCGCAG GCAAAACCTA TAAAGTTTAC GGCGGCTTGT


 


1151
GGCTGATGGT TTGGGTCTTC CTTTTCGGCA TCGTCAACAT CGCCGCACAG


 


1201
GTATTGAGCC AAATGGAACT CGTCCCCGTA TTTAAAGGAT AA






This corresponds to the amino acid sequence <SEQ ID 360; ORF 102>:










m102.pep..




1
MPNKTPSLFG GAMIIAGTVI GAGMLANPTA TSGVWFTGSL AVLLYTWFSM


 


51
LSSGLMILEV NTHYPHGASF DTMVKDLLGR GWNIINGIAV AFVLYLLTYA


 


101
YIFVGGDLTA KGLGSAAGGD VSLTVGQLVF FGILAFCVWA SARLVDRFTG


 


151
VLIGGMVLTF IWAAGGLIAD AKPSVLFDTQ APAGTNYWIY AATALPVCLA


 


201
SFGFHGNVSS LLKYFKGDAP KVAKSIWTGT LIALVIYVLW QTAIQGNLPR


 


251
NEFAPVIAAE GQVSVLIETL SKFAQTGNMD KILSLFSYMA IATSFLGVTL


 


301
GLFDYIADIF KWNDSISGRT KTAALTFLPP LISCLLFPTG FVTAIGYVGL


 


351
AATVWTGIIP AMLLYRSRKK FGAGKTYKVY GGLWLMVWVF LFGIVNIAAQ


 


401
VLSQMELVPV FKG*






m102/g102 86.0% identity in 415 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 361>:










a102.seq




1
ATGCCCACCA AAACCCCTTC ACTGTTCGGC GGCGCGATGA TTATCGCCGG


 


51
CACGNTCATC GGCGCAGGTA TGCTCGCCAA CCCGACCGCC ACATCCGGCG


 


101
TATGGTTTAC CGGCTCGCTG GCCGTGTTGC TGTACACCTG GTTTTCCATG


 


151
CTCTCCAGCG GCCTGATGAT TTTGGAAGTC AACACCCACT ACCCCCACGG


 


201
CGCGANCTTC GACACCATGG TTAAAGACCT GCTCGGACGG AGCTGGAACA


 


251
TCATCAACGG CATCGCCGTC GCCTTCGTTT TATACCTGCT TACTTACGCT


 


301
TATATCTTCG TCGGCGGCGA CCTGACCGCC AAAGGCTTAG GCAGCGCGGC


 


351
AGGCGGCAAT GTTTCACTCA CCGTCGGACA ACTCGTCTTC TTCGGCATTC


 


401
TCGCCTTTTG CGTATGGGCA TCCGCACGCT TGGTCGACCG ATTCACCAGC


 


451
GTCCTCATCG GCGGCATGGT ATTAACCTTT ATTTGGGCAA CCGGCGGCCT


 


501
GATTGCCGAT GCCAAACTGC CCGTCCTCTT CGACACCCAA GCCCCTACCG


 


551
GCACCAACTA CTGGATTTAT GTCGCCACCG CCCTGCCCGT CTGCCTTGCG


 


601
TCATTCGGTT TCCACGGCAA CGTCTCCAGC CTGCTCAAAT ACTTTAAAGG


 


651
CGACGCGCCC AAAGTGGCTA AATCCATCTG GACGGGCACA CTGATTGCGC


 


701
TGGTAATTTA CGTCCTCTGG CAAACCGCCA TCCAANGCAA CCTGCCGCGC


 


751
AACGAGTTCG CCCCCGTGAT TGCCGCCGAA GGGCAAGTCT CCGTCNTGAT


 


801
TGAAACCCTG TCCAAATTCG CCCAAACCGG CAATATGGAC AAAATATTGT


 


851
CCCTGTTTTC CTATATGGCG ATCGCCACCT CGTTTTTAGG CGTAACGCTC


 


901
GGACTCTTCG ACTACATCGC CGACATCTTC AAATGGAACG ACAGCGTGTC


 


951
CGGCCGCACC AAAACCGCCG CGCTGACCTT CCTGCCGCCT NTAATTTCCT


 


1001
GCCTGCTCTT CCCCACCGGC TTTGTTACCG CCATCGGNTA CGTCGGCCTG


 


1051
GCGGCAACCG TCTGGACAGG CATCATCCCC GCCATGCTGC TNTACCGTTC


 


1101
GCGCAAAAAA TTCGGCGCAG GCAAAACCTA TAAAGTTTAC GGCGGCTTGT


 


1151
GGCTGATGGT TTGGGTCTTC CTTTTCGGCA TCNTCAACAT CGCCGCACAN


 


1201
GTATTGAGCC AAATGGAACT CGTCCCCGTA TTTAAAGGAT AA


 


1202






This corresponds to the amino acid sequence <SEQ ID 362; ORF 102.a>:










a102.pep




1
MPTKTPSLFG GAMIIAGTXI GAGMLANPTA TSGVWFTGSL AVLLYTWFSM


 


51
LSSGLMILEV NTHYPHGAXF DTMVKDLLGR SWNIINGIAV AFVLYLLTYA


 


101
YIFVGGDLTA KGLGSAAGGN VSLTVGQLVF FGILAFCVWA SARLVDRFTS


 


151
VLIGGMVLTF IWATGGLIAD AKLPVLFDTQ APTGTNYWIY VATALPVCLA


 


201
SFGFHGNVSS LLKYFKGDAP KVAKSIWTGT LIALVIYVLW QTAIQXNLPR


 


251
NEFAPVIAAE GQVSVXIETL SKFAQTGNMD KILSLFSYMA IATSFLGVTL


 


301
GLFDYIADIF KWNDSVSGRT KTAALTFLPP XISCLLFPTG FVTAIGYVGL


 


351
AATVWTGIIP AMLLYRSRKK FGAGKTYKVY GGLWLMVWVF LFGIXNIAAX


 


401
VLSQMELVPV FKG*






m102/a102 95.9% identity in 413 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 363>:










g105.seq




1
Atgtccgcag aaaCATACAc acAAAtcggc tGGgtaggct taggGcaaat


 


51
gGgtctgcct atgGTAACGC GGCTCTTGGA CGGCGGCATC GAAGTCGGCG


 


101
TATACAACCG CTCGCCCGAC AAAACTGCCC CCATCTCcgc CAAAGGAGCA


 


151
AAAGTTTACG GCagcACCGC CGAACTCGTC CGCGCCTGCC CCGTCATTTT


 


201
CCTGATGGTT TCCGACTATG CCGCCGTGTG CGACATCCTG AACGGAGTCC


 


251
GCGACGGATT GGCCGGCAAA ATCATCGTCA ACATGAGCAC CATCTCCCCG


 


301
ACCGAAAACC TCGCCGTCAA AGCACTTGTC GAAGCCGCAG GCGGACAGTT


 


351
TGCCGAAGCA CCCGTTTCCG GATCGGTCGG ACCCGCCACC AACGGCACAC


 


401
TGCTGATTCT GTTCGGCGGC AGCGAAGCCG TTTTAAACCC GCTGCAAAAA


 


451
ATATTTTCCC TTGTCGGCAA AAAAACCTTC CATTTCGGCG ATGTCGGCAA


 


501
AGGCTCGGGC GCGAAACTCG TCTTGAACTC GCTCTTAGGC ATTTTCGGCG


 


551
AAGCGTACAG CGAAGCGATG CTGATGGCGC GGCAGTTCGG CATCGATACC


 


601
GACACCATCG TCGAAGCCAT CGGCGGCTCG GCAATGGACT CGCCTATGTT


 


651
TCAAACAAAA AAATCACTAT GGGCAAACCG TGAGTTCCCC CCTGCCTTTG


 


701
CACTCAAACA CGCTTCCAAA GAcctTAACC TCGccgtcAA AGAGCTTGAA


 


751
CAGGCAGGCA ACACCCTGCC CGCCGTCGAA ACCGTTGCTG CCAGCTACCG


 


801
CAAAGCAGTT GAAGCCGGCT ACGGCGAACA GGACGTTTCC GGCGTTTACC


 


851
TGAAATTGGC AGAACACTGA






This corresponds to the amino acid sequence <SEQ ID 364; ORF 105.ng>:










g105.pep




1
MSAETYTQIG WVGLGQMGLP MVTRLLDGGI EVGVYNRSPD KTAPISAKGA


 


51
KVYGSTAELV RACPVIFLMV SDYAAVCDIL NGVRDGLAGK IIVNMSTISP


 


101
TENLAVKALV EAAGGQFAEA PVSGSVGPAT NGTLLILFGG SEAVLNPLQK


 


151
IFSLVGKKTF HFGDVGKGSG AKLVLNSLLG IFGEAYSEAM LMARQFGIDT


 


201
DTIVEAIGGS AMDSPMFQTK KSLWANREFP PAFALKHASK DLNLAVKELE


 


251
QAGNTLPAVE TVAASYRKAV EAGYGEQDVS GVYLKLAEH






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 365>:










m105.seq




1
ATGTCCGCAA ACGAATACGC ACAAATCGGC TGGaTAGGCT TAGGGCAAAT


 


51
GGGTCTGCCT ATGGTAACGC GGCTCTTGGA CGGCGGCATC GAAGTCGGCG


 


101
TATACAACCG CTCGCCCGAC AAAACTGCCC CCATCTCCGC CAAAGGCGCA


 


151
AAAGTTTACG GCAACACCGC CGAACTCGTC CGCGACTATC CCGTCATTTT


 


201
CCTGATGGTT TCCGACTATG CCGCCGTGTG CGACATCCTG AACGGAGTCC


 


251
GCGACGGATT GGCCGGCAAm ATCATCGTCA ACATGAGCAC CATCTCCCCG


 


301
ACCGAAAaGC TCGCCGTCAA AGCACTTGTC GAAGCGCAGm GaCAGTTTGC


 


351
CGAAGCACCC GTTTCCGGAT CGGTCGGGCC CGCCACCAAC GGCACGCTGC


 


401
TGATTCTGTT CGGCGGCAGC GAAcCGtTTT AAACCCGCTG CAAAAAATAT


 


451
TTTCCCTCGT CGGCAAAAAA ACCTTCCATT TCGGCGATGT CGGCAAAGGT


 


501
TCGGGCGCGA AACTCGTCTT GAACTCGCTC TTGGGCATTT TCGGCGAaCG


 


551
TAcAGCGAAs GmTgCTGATG GCGCGGCAGT TCGGCATCGA TACCGACACC


 


601
ATCGTCGAAG CCATCGGsGA CTCGGCAATG GACTCGCCCA TGTTCCAAAC


 


651
CAAAAAATCC CTGTGGGCAA ACCGCGAATT CCCGmCCGmC TTCGCCCTCA


 


701
AACACGCCTC CAAAGACCTC AACCTCGCCG TCAAAGAGCT TGAACAGGCA


 


751
GGCAACACCC TGCCCGCCGT CGAAACCGTT GCTGCCAGCT ACCGCAAAGC


 


801
AGTCGAAGCC GGCTACGGGA CACAGGACGT TTCCGGCGTT TACCTGAAAC


 


851
TGGCAGAACA CTGA






This corresponds to the amino acid sequence <SEQ ID 366; ORF 105>:










m105.pep




1
MSANEYAQIG WIGLGQMGLP MVTRLLDGGI EVGVYNRSPD KTAPISAKGA


 


51
KVYGNTAELV RDYPVIFLMV SDYAAVCDIL NGVRDGLAGX IIVNMSTISP


 


101
TEKLAVKALV EAQRQFAEAP VSGSVGPATN GTLLILFGGS EPFXTRCKKY


 


151
FPSSAKKPSI SAMSAKVRAR NSSXTRSWAF SANVQRXXLM ARQFGIDTDT


 


201
IVEAIGDSAM DSPMFQTKKS LWANREFPXX FALKHASKDL NLAVKELEQA


 


251
GNTLPAVETV AASYRKAVEA GYGTQDVSGV YLKLAEH






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 105 shows 79.9% identity over a 289 aa overlap with a predicted ORF (ORF 105.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 367>:










a105.seq




1
ATGTCCGCAA ACGAATACAC ACAAATCGGC TGGATAGGCT TAGGGCAAAT


 


51
GGGTCTGCCT ATGGTAACGC GGCTCTTGGA CGGCGGCATC GAAGTCGGCG


 


101
TATACAACCG CTCGCCCGAC AAAACTGCCC CCATCTCCGC CAAAGGCGCA


 


151
AAAGTTTACG GCAACACCGC CGAACTCGTC CGCGACTATC CCGTCATTTT


 


201
CCTGATGGTT TCCGACTATG CCGCCGTGTG CGACATCCTG AACGGAGTCC


 


251
GCGACGGATT GGCCGGCAAA ATCATCGTCA ACATGAGCAC CATCTCCCCG


 


301
ACCGAAAACC TCGCCGTCAA AGCACTTGTC GAAGCCGCAG GCGGACAGTT


 


351
TGCCGAAGCA CCCGTTTCCG GATCGGTCGG GCCCGCCACC AACGGCACGC


 


401
TGCTGATTCT GTTCGGCGGC AGCGAAGCCG TTTTAAACCC GCTGCAAAAA


 


451
ATATTTTCCC TCGTCGGCAA AAAAACCTTC CATTTCGGCG ATGTCGGCAA


 


501
AGGTTCGGGC GCGAAACTCG TCTTGAACTC GCTCTTGGGC ATTTTCGGCG


 


551
AAGCGTACAG CGAAGCGATG CTGATGGCGC GGCAGTTCGG CATCGATACC


 


601
GACACCATCG TCGAAGCCAT CGGCGGCTCG GCAATGGACT CGCCCATGTT


 


651
CCAAACCAAA AAATCCCTGT GGGCAAACCG CGAATTCCCA CCCGCCTTCG


 


701
CCCTCAAACA CGCCTCCAAA GACCTCAACC TCGCCGTCAA AGAGCTTGAA


 


751
CAGGCAGGCA ACACCCTGCC CGCCGTCGAA ACCGTTGCTG CCAGCTACCG


 


801
CAAAGCAGTC GAAGCCGGCT ACGGCGAACA GGACGTTTCC GGCGTTTACC


 


851
TGAAATTGGC AGAACACTGA






This corresponds to the amino acid sequence <SEQ ID 368; ORF 105.a>:










a105.pep




1
MSANEYTQIG WIGLGQMGLP MVTRLLDGGI EVGVYNRSPD KTAPISAKGA


 


51
KVYGNTAELV RDYPVIFLMV SDYAAVCDIL NGVRDGLAGK IIVNMSTISP


 


101
TENLAVKALV EAAGGQFAEA PVSGSVGPAT NGTLLILFGG SEAVLNPLQK


 


151
IFSLVGKKTF HFGDVGKGSG AKLVLNSLLG IFGEAYSEAM LMARQFGIDT


 


201
DTIVEAIGGS AMDSPMFQTK KSLWANREFP PAFALKHASK DLNLAVKELE


 


251
QAGNTLPAVE TVAASYRKAV EAGYGEQDVS GVYLKLAEH*






m105/a105 96.5% identity in 289 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 369>:










g105-1.seq




1
ATGTCCGCAG AAACATACAC ACAAATCGGC TGGGTAGGCT TAGGGCAAAT


 


51
GGGTCTGCCT ATGGTAACGC GGCTCTTGGA CGGCGGCATC GAAGTCGGCG


 


101
TATACAACCG CTCGCCCGAC AAAACTGCCC CCATCTCCGC CAAAGGAGCA


 


151
AAAGTTTACG GCAGCACCGC CGAACTCGTC CGCGCCTGCC CCGTCATTTT


 


201
CCTGATGGTT TCCGACTATG CCGCCGTGTG CGACATCCTG AACGGAGTCC


 


251
GCGACGGATT GGCCGGCAAA ATCATCGTCA ACATGAGCAC CATCTCCCCG


 


301
ACCGAAAACC TCGCCGTCAA AGCACTTGTC GAAGCCGCAG GCGGACAGTT


 


351
TGCCGAAGCA CCCGTTTCCG GATCGGTCGG ACCCGCCACC AACGGCACAC


 


401
TGCTGATTCT GTTCGGCGGC AGCGAAGCCG TTTTAAACCC GCTGCAAAAA


 


451
ATATTTTCCC TTGTCGGCAA AAAAACCTTC CATTTCGGCG ATGTCGGCAA


 


501
AGGCTCGGGC GCGAAACTCG TCTTGAACTC GCTCTTAGGC ATTTTCGGCG


 


551
AAGCGTACAG CGAAGCGATG CTGATGGCGC GGCAGTTCGG CATCGATACC


 


601
GACACCATCG TCGAAGCCAT CGGCGGCTCG GCAATGGACT CGCCTATGTT


 


651
TCAAACAAAA AAATCACTAT GGGCAAACCG TGAGTTCCCC CCTGCCTTTG


 


701
CACTCAAACA CGCTTCCAAA GACCTTAACC TCGCCGTCAA AGAGCTTGAA


 


751
CAGGCAGGCA ACACCCTGCC CGCCGTCGAA ACCGTTGCTG CCAGCTACCG


 


801
CAAAGCAGTT GAAGCCGGCT ACGGCGAACA GGACGTTTCC GGCGTTTACC


 


851
TGAAATTGGC AGAACACTGA






This corresponds to the amino acid sentence <SEQ ID 370; ORF 105-1.ng>:










g105-1.pep




1
MSAETYTQIG WVGLGQMGLP MVTRLLDGGI EVGVYNRSPD KTAPISAKGA


 


51
KVYGSTAELV RACPVIFLMV SDYAAVCDIL NGVRDGLAGK IIVNMSTISP


 


101
TENLAVKALV EAAGGQFAEA PVSGSVGPAT NGTLLILFGG SEAVLNPLQK


 


151
IFSLVGKKTF HFGDVGKGSG AKLVLNSLLG IFGEAYSEAM LMARQFGIDT


 


201
DTIVEAIGGS AMDSPMFQTK KSLWANREFP PAFALKHASK DLNLAVKELE


 


251
QAGNTLPAVE TVAASYRKAV EAGYGEQDVS GVYLKLAEH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 371>:










m105-1.seq




1
ATGTCCGCAA ACGAATACGC ACAAATCGGC TGGATAGGCT TAGGGCAAAT


 


51
GGGTCTGCCT ATGGTAACGC GGCTCTTGGA CGGCGGCATC GAAGTCGGCG


 


101
TATACAACCG CTCGCCCGAC AAAACTGCCC CCATCTCCGC CAAAGGCGCA


 


151
AAAGTTTACG GCAACACCGC CGAACTCGTC CGCGACTATC CCGTCATTTT


 


201
CCTGATGGTT TCCGACTATG CCGCCGTGTG CGACATCCTG AACGGAGTCC


 


251
GCGACGGATT GGCCGGCAAA ATCATCGTCA ACATGAGCAC CATCTCCCCG


 


301
ACCGAAAACC TCGCCGTCAA AGCACTTGTC GAAGCCGCAG GCGGACAGTT


 


351
TGCCGAAGCA CCCGTTTCCG GATCGGTCGG GCCCGCCACC AACGGCACGC


 


401
TGCTGATTCT GTTCGGCGGC AGCGAAGCcG TTTTAAACCC GCTGCAAAAA


 


451
ATATTTTCCC TCGTCGGCAA AAAAACCTTC CATTTCGGCG ATGTCGGCAA


 


501
AGGTTCGGGC GCGAAACTCG TCTTGAACTC GCTCTTGGGC ATTTTCGGCG


 


551
AAGCGTACAG CGAAnCGATG CTGATGGCGC GGCAGTTCGG CATCGATACC


 


601
GACACCATCG TCGAAGCCAT CGGsGACTCG GCAATGGACT CGCCCATGTT


 


651
CCAAACCAAA AAATCCCTGT GGGCAAACCG CGAATTCCCG CCCGCCTTCG


 


701
CCCTCAAACA CGCCTCCAAA GACCTCAACC TCGCCGTCAA AGAGCTTGAA


 


751
CAGGCAGGCA ACACCCTGCC CGCCGTCGAA ACCGTTGCTG CCAGCTACCG


 


801
CAAAGCAGTC GAAGCCGGCT ACGGCGAACA GGACGTTTCC GGCGTTTACC


 


851
TGAAACTGGC AGAACACTGA






This corresponds to the amino acid sequence <SEQ ID 372; ORF 105-1>:










m105-1.pep




1
MSANEYAQIG WIGLGQMGLP MVTRLLDGGI EVGVYNRSPD KTAPISAKGA


 


51
KVYGNTAELV RDYPVIFLMV SDYAAVCDIL NGVRDGLAGK IIVNMSTISP


 


101
TENLAVKALV EAAGGQFAEA PVSGSVGPAT NGTLLILFGG SEAVLNPLQK


 


151
IFSLVGKKTF HFGDVGKGSG AKLVLNSLLG IFGEAYSEXM LMARQFGIDT


 


201
DTIVEAIGDS AMDSPMFQTK KSLWANREFP PAFALKHASK DLNLAVKELE


 


251
QAGNTLPAVE TVAASYRKAV EAGYGEQDVS GVYLKLAEH*






m105-1/g105-1 96.9% identity in 289 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 373>:










a105-1.seq




1
ATGTCCGCAA ACGAATACAC ACAAATCGGC TGGATAGGCT TAGGGCAAAT


 


51
GGGTCTGCCT ATGGTAACGC GGCTCTTGGA CGGCGGCATC GAAGTCGGCG


 


101
TATACAACCG CTCGCCCGAC AAAACTGCCC CCATCTCCGC CAAAGGCGCA


 


151
AAAGTTTACG GCAACACCGC CGAACTCGTC CGCGACTATC CCGTCATTTT


 


201
CCTGATGGTT TCCGACTATG CCGCCGTGTG CGACATCCTG AACGGAGTCC


 


251
GCGACGGATT GGCCGGCAAA ATCATCGTCA ACATGAGCAC CATCTCCCCG


 


301
ACCGAAAACC TCGCCGTCAA AGCACTTGTC GAAGCCGCAG GCGGACAGTT


 


351
TGCCGAAGCA CCCGTTTCCG GATCGGTCGG GCCCGCCACC AACGGCACGC


 


401
TGCTGATTCT GTTCGGCGGC AGCGAAGCCG TTTTAAACCC GCTGCAAAAA


 


451
ATATTTTCCC TCGTCGGCAA AAAAACCTTC CATTTCGGCG ATGTCGGCAA


 


501
AGGTTCGGGC GCGAAACTCG TCTTGAACTC GCTCTTGGGC ATTTTCGGCG


 


551
AAGCGTACAG CGAAGCGATG CTGATGGCGC GGCAGTTCGG CATCGATACC


 


601
GACACCATCG TCGAAGCCAT CGGCGGCTCG GCAATGGACT CGCCCATGTT


 


651
CCAAACCAAA AAATCCCTGT GGGCAAACCG CGAATTCCCA CCCGCCTTCG


 


701
CCCTCAAACA CGCCTCCAAA GACCTCAACC TCGCCGTCAA AGAGCTTGAA


 


751
CAGGCAGGCA ACACCCTGCC CGCCGTCGAA ACCGTTGCTG CCAGCTACCG


 


801
CAAAGCAGTC GAAGCCGGCT ACGGCGAACA GGACGTTTCC GGCGTTTACC


 


851
TGAAATTGGC AGAACACTGA






This corresponds to the amino acid sequence <SEQ ID 374; ORF 105-1.a>:










a105-1.pep




1
MSANEYTQIG WIGLGQMGLP MVTRLLDGGI EVGVYNRSPD KTAPISAKGA


 


51
KVYGNTAELV RDYPVIFLMV SDYAAVCDIL NGVRDGLAGK IIVNMSTISP


 


101
TENLAVKALV EAAGGQFAEA PVSGSVGPAT NGTLLILFGG SEAVLNPLQK


 


151
IFSLVGKKTF HFGDVGKGSG AKLVLNSLLG IFGEAYSEAM LMARQFGIDT


 


201
DTIVEAIGGS AMDSPMFQTK KSLWANREFP PAFALKHASK DLNLAVKELE


 


251
QAGNTLPAVE TVAASYRKAV EAGYGEQDVS GVYLKLAEH*






a105-1/m105-1 99.0% identity in 289 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 375>:










g107.seq




1
ATGGTATTAA CCTTTATTTG GGCAACCGGC GGCCTGGTTG CCGATGCCAA


 


51
ACCGTCCGTC CTCTTCGACA CCCAAGCCCC CGTCGGCACC GGCTACTGGA


 


101
TTTACGCCGC CACCGCCCTG CCCGTCTGCC TCGCTTCCTT CGGCTTCCAC


 


151
GGCAACGTTT CCAGCCTGCT CAAATACTTT AAAGGCGACG cgcCcaaagt


 


201
GgCGAaATCc atctggGcag gtacattggT TGCCttggta atttacgtcc


 


251
TCTggcaaac cgccatCcaa agcaaccTGC cgcgcaacga gttcgcCCCc


 


301
gtgattgccg ccgagaggca actCTCCGTC CTgaatgaaa cccTGtccaa


 


351
attcgcccaa accggcgata tggataAaat attgtcccta tttccctaca


 


401
tggcaatcgc cacctccttt ttaggcgTAA Ccttaggcct gtttgacaac


 


451
atcgccggac atcttcaaat ggaacgacag tatgtccggg cggcaccaaa


 


501
accgtcgcgc tga






This corresponds to the amino acid sequence <SEQ ID 376; ORF 107.ng>:










g107.pep




1
MVLTFIWATG GLVADAKPSV LFDTQAPVGT GYWIYAATAL PVCLASFGFH


 


51
GNVSSLLKYF KGDAPKVAKS IWAGTLVALV IYVLWQTAIQ SNLPRNEFAP


 


101
VIAAERQLSV LNETLSKFAQ TGDMDKILSL FPYMAIATSF LGVTLGLFDN


 


151
IAGHLQMERQ YVRAAPKPSR *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 377>:










m107.seq




1
ATGGTATTGA CCTTTATTTG GGCGGCCGGC GGGCTGATTG CCGATGCCAA


 


51
GCCGTCCGTC CTCTTCGATA CCCAAGCCCC CGCCGGCACA AACTACTGGA


 


101
TTTACGCCGs CACCGCCCTG CCCGTCTGCC TCGCTTCCTT CGGCTTCCAC


 


151
GGCAACGTCT CCAGCCTGCT CAAATACTTT AAAGGCGACG CGCCCAAAGT


 


201
GGCTAAATCC ATCTGGACGG GCACACTGAT TGCGCTGGTA ATTTACGTCC


 


251
TCTGGCAAAC CGCCATCCAA GGCAACCTGC CGCGCAACGA GTTCGCCCCC


 


301
GTCATCGCCG CCGAAGGGCA AGTCTCCGTC CTCATCGAAA CCCTGTCCAA


 


351
ATTCGCCCAA ACCGGCAATA TGGACAAAAT ATTGTCCCTG TTTTCCTATA


 


401
TGGCGATCGC CACCTCGTTT TTAGGCGTAA CGCTCGGACT CTTCGACTAC


 


451
ATCGCCCATC TTCAAATGGA ACGACAGCAT CTCCGGgCCG CACCAAAACC


 


501
GCCGCGCTGA






This corresponds to the amino acid sequence <SEQ ID 378; ORF 107>:










m107.pep..




1
MVLTFIWAAG GLIADAKPSV LFDTQAPAGT NYWIYAXTAL PVCLASFGFH


 


51
GNVSSLLKYF KGDAPKVAKS IWTGTLIALV IYVLWQTAIQ GNLPRNEFAP


 


101
VIAAEGQVSV LIETLSKFAQ TGNMDKILSL FSYMAIATSF LGVTLGLFDY


 


151
IAHLQMERQH LRAAPKPPR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 107 shows 89.4% identity over a 170 aa overlap with a predicted ORF (ORF 107.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 379>:










a107.seq




1
ATGGTATTAA CCTTTATTTG GGCAACCGGC GGCCTGATTG CCGATGCCAA


 


51
ACTGCCCGTC CTCTTCGACA CCCAAGCCCC TACCGGCACC AACTACTGGA


 


101
TTTATGTCGC CACCGCCCTG CCCGTCTGCC TTGCGTCATT CGGTTTCCAC


 


151
GGCAACGTCT CCAGCCTGCT CAAATACTTT AAAGGCGACG CGCCCAAAGT


 


201
GGCTAAATCC ATCTGGACGG GCACACTGAT TGCGCTGGTA ATTTACGTCC


 


251
TCTGGCAAAC CGCCATCCAA GGCAACCTGC CGCGCAACGA GTTCGCCCCC


 


301
GTGATTGCCG CCGAAGGGCA AGTCTCCGTC CTGATTGAAA CCCTGTCCAA


 


351
ATTCGCCCAA ACCGGCAATA TGGACAAAAT ATTGTCCCTG TTTTCCTATA


 


401
TGGCGATCGC CACCTCGTTT TTAGGCGTAA CGCTCGGACT CTTCGACTAC


 


451
ATCGCCGACA TCTTCAAATG GAACGACAGC GTGTCCGGCC GCACCAAAAC


 


501
CGCCGCGCTG ACCTTCCTGC CGCCTCTAAT TTCCTGCCTG CTCTTCCCCA


 


551
CCGGCTTTGT TACCGCCATC GGCTACGTCG GCCTGGCGGC AACCGTCTGG


 


601
ACAGGCATCA TCCCCGCCAT GCTGCTCTAC CGTTCGCGCA AAAAATTCGG


 


651
CGCAGGCAAA ACCTATAAAG TTTACGGCGG CTTGTGGCTG ATGGTTTGGG


 


701
TCTTCCTTTT CGGCATCGTC AACATCGCCG CACAGGTATT GAGCCAAATG


 


751
GAACTCGTCC CCGTATTTAA AGGATAA






This corresponds to the amino acid sequence <SEQ ID 380; ORF 107.a>:










a107.pep




1
MVLTFIWATG GLIADAKLPV LFDTQAPTGT NYWIYVATAL PVCLASFGFH


 


51
GNVSSLLKYF KGDAPKVAKS IWTGTLIALV IYVLWQTAIQ GNLPRNEFAP


 


101
VIAAEGQVSV LIETLSKFAQ TGNMDKILSL FSYMAIATSF LGVTLGLFDY


 


151
IADIFKWNDS VSGRTKTAAL TFLPPLISCL LFPTGFVTAI GYVGLAATVW


 


201
TGIIPAMLLY RSRKKFGAGK TYKVYGGLWL MVWVFLFGIV NIAAQVLSQM


 


251
ELVPVFKG*






m107/a107 94.8% identity in 154 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 381>:










g108.seq




1
ATGttgccgg gCTTCAACCG GATATTCAaa cggTTTGCTC CAACACTCGG


 


51
AAcggCGCAT AAAACGCCgc ccTTCGCGTT ATCCCGAACG GGGCGGCTAA


 


101
TCAGATCCTA TCGCCATAAA AGGCGGGGTT TCAACCGAAA AGGAATTGAG


 


151
ATGAATAAAA CCTTGTCTAT TTTGCCGGCG GCAATCTTAC TCGGCGGGTG


 


201
CGCCGCCGGC GGCAACACAT TCGGCAGCTT AGACGGCGGC ACGGGTATGG


 


251
GTGGCAGCAT CGTCAAAATG ACGGTAGAAA gccAATGCCG TGCGGAATTG


 


301
GACAGGCGCA GCGAATGGCG TTTGACCGCG CTGGCGATGA GTGCCGAAAA


 


351
ACAGGCGGAA TGGGAAAACA AGATTTGCGG CTGCGCTACC GAAGAAGCAC


 


401
CTAACCAGCT GACCGGCAAC GATGTGATGC AGATGCTGAa ccagtccacG


 


451
CGCaatcagg cacTtgccgc CCtgaccgTC AAAacggtTT CcgcctgcTT


 


501
CAaacgcctg tACCGCTAa






This corresponds to the amino acid sequence <SEQ ID 382; ORF 108.ng>:










g108.pep




1
MLPGFNRIFK RFAPTLGTAH KTPPFALSRT GRLIRSYRHK RRGFNRKGIE


 


51
MNKTLSILPA AILLGGCAAG GNTFGSLDGG TGMGGSIVKM TVESQCRAEL


 


101
DRRSEWRLTA LAMSAEKQAE WENKICGCAT EEAPNQLTGN DVMQMLNQST


 


151
RNQALAALTV KTVSACFKRL YR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 383>:










m108.seq




1
ATGTTGCCGG GCTTCAACCG GATATTCAAA CGGTTTGTTC CAACACTCGG


 


51
AACGGCGCAT AAAACGCCGC CCTTCGCGTT ATCCCGAACG GGGCGGCTAA


 


101
TCAGATTCTA TCGCCATAAA AGGCGGGGTT TCAACCGAAA AGGAATTGAG


 


151
ATGAATAAAA CCTTGTCTAT TTTGCCGGTG GCAATCTTAC TCGGCGGCTG


 


201
CGCCGCCGGA GGCGGTAACA CATTCGGCAG CTTAGACGGT GGCACAGGCA


 


251
TGGGCGGCAG CATCGTCAAA ATGGCGGTTG GGAGCCAATG CCGTGCGGAA


 


301
TTGGACAAAC GCAGCGAATG GCGTTTGACC GCGCTGGCGA TGAGTGCCGA


 


351
AAAACAGGCG GAGTGGGAAA ACAAGATTTG CGCTTGCGTC GCCCAAGAAG


 


401
CACCCGAACG GATGACCGGC AACGATGTGA TGCAGATGCT GGCTCCGTCC


 


451
ACGCGCAATC AGGCACTTGC CGCCCTGACC GCCAAAACGG TTTCCGCCTG


 


501
CTTCAAACAC CTGTACCGCT AA






This corresponds to the amino acid sequence <SEQ ID 384; ORF 108>:










m108.pep




1
MLPGFNRIFK RFVPTLGTAH KTPPFALSRT GRLIRFYRHK RRGFNRKGIE


 


51
MNKTLSILPV AILLGGCAAG GGNTFGSLDG GTGMGGSIVK MAVGSQCRAE


 


101
LDKRSEWRLT ALAMSAEKQA EWENKICACV AQEAPERMTG NDVMQMLAPS


 


151
TRNQALAALT AKTVSACFKH LYR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 108 shows 89.6% identity over a 173 aa overlap with a predicted ORF (ORF 108.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 385>:










a108.seq




1
ATGTTGCCGG GCTTCAACCG GATATTCAAA CGGTTTGTTC CAACACTCGG


 


51
AACGGCGCAT AAAACGCCGC CCTTCGCGTT ATCCCGAACG GGGCGGCTAA


 


101
TCAGATTCTA TCGCCATAAA AGGCGGGGTT TCAACCGAAA AGGAATTGAG


 


151
ATGAATAAAA CCTTGTCTAT TTTGCCGGTG GCAATCTTAC TCGGCGGCTG


 


201
CGCCGCCGGG GGCGGTAACA CATTCGGCAG CTTAGACGGC GGCACAGGTA


 


251
TGGGCGGCAG CATCGTCAAA ATGGCGGTAG AAAGCCAATG CCGTGCGGAA


 


301
TTGAACAAAC GCAGCGAATG GCGTTTGACC GCGCTGGCGA TGAGTGCCGA


 


351
AAAACAGGCG GAATGGGAAA ACAAGATTTG CGCTTGCGTC GCCCAAGAAG


 


401
CACCCAACCA GCTGACCGGC AACGATGTGA TGCAGATGCT GGATCCGTCC


 


451
ACGCGCAATC AGGCACTTGC CGCCCTGACC GCCAAAACGG TTTCCGCCTG


 


501
CTTCAAACAC CTGTACCGCT AA






This corresponds to the amino acid sequence <SEQ ID 386; ORF 108.a>:










a108.pep




1
MLPGFNRIFK RFVPTLGTAH KTPPFALSRT GRLIRFYRHK RRGFNRKGIE


 


51
MNKTLSILPV AILLGGCAAG GGNTFGSLDG GTGMGGSIVK MAVESQCRAE


 


101
LNKRSEWRLT ALAMSAEKQA EWENKICACV AQEAPNQLTG NDVMQMLDPS


 


151
TRNQALAALT AKTVSACFKH LYR*






m108/a108 96.5% identity in 173 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 387>:










g109.seq




1
ATGTATTATC GCCGGGTTGT GGGGCTATCC GATGGACTTG GCGATTTGGC


 


51
AGCCGGTATT GATCGTAGGC GTATGCTTAC CGCTTTTGGA AGCGGGCATG


 


101
GAAATGACGC GCAAAGGCAA AACCACCCAA TCCGCCGCCA TCGTGGTGTT


 


151
CTCTTCCGTC TGGTCAATCC GGTTTTCGGC TGGGCGTTGA CGATGCTGTT


 


201
GGATAATTTG GGCTTAATCG GCTGCAAAGA ACGCAGCGCG CAATTAGGTT


 


251
TTGTCGGACG AGTATTGATA CCCGCAGTAG GTTTCTTAAT CTTGTGTGTG


 


301
GCGATGGGTG CGGTCGGGAT GCTGCCCGGT ATCCCTCCGT TTTTGGAGCA


 


351
GTTCAAATCT TTGGGCTAG






This corresponds to the amino acid sequence <SEQ ID 388; ORF 109.ng>:










g109.pep




1
MYYRRVVGLS DGLGDLAAGI DRRRMLTAFG SGHGNDAQRQ NHPIRRHRGV


 


51
LFRLVNPVFG WALTMLLDNL GLIGCKERSA QLGFVGRVLI PAVGFLILCV


 


101
AMGAVGMLPG IPPFLEQFKS LG






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 389>:










m109.seq




1
ATGTATTATC GCCGGGTTAT GGGGCTATCC GATGGACTTG GCGATTTGGC


 


51
AGCCGGTATT GAGCGTAGCC TTGGTCGTAG GCGTATACTT ACCGCTTTTG


 


101
GAAGCGGGCA TGGAAATGAC GCGCAAAGGC AAAACCACCC AATCCGCCGC


 


151
CATCGTGGTG TTCTCTTCCG CCTTGTCAAT CCGGTTTTCG GCTGGGCGTT


 


201
GACGATGCTG TTGGATAATT TGGGCTTAAT CGGCTGCAAA GAGCGCAGTG


 


251
CGCAATTAGG TTTCGCCGGA CGCGTGTTGA TACCCGCAGT AGGTTTCTTG


 


301
ATCTTGTGTG TGGCGATGGG TGCGGTCGGG ATGCTGCCCG GTATCCCGCC


 


351
GTTTTTGGAA CACTTCAAAT CTTTGGGCTA G






This corresponds to the amino acid sequence <SEQ ID 4; ORF 109>:










m109.pep




1
MYYRRVMGLS DGLGDLAAGI ERSLGRRRIL TAFGSGHGND AQRQNHPIRR


 


51
HRGVLFRLVN PVFGWALTML LDNLGLIGCK ERSAQLGFAG RVLIPAVGFL


 


101
ILCVAMGAVG MLPGIPPFLE HFKSLG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 109 shows 92.9% identity over a 126 aa overlap with a predicted ORF (ORF 109.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 391>:










a109.seq




1
ATGTATTATC GCCGGGTTGT GGGGCTATCC GATGGACTTG GCGATTTGGC


 


51
AGCCGGTATT GAGCGTAGCC TTGGTCGTAG GCGTATACTT ACCGCTTTTG


 


101
GAAGCGGGCA TGGAAATGAC GCGCAAAGGC AAAACCACCC AATCCGCCGC


 


151
CACCGTGGTG TTCTCTTCCG CTTGGTCAAT CCGGTTTTCG GCTGGGCGTT


 


201
GACGATGCTG TTGGATAATT TGGGCTTAAT CGGCTGCAAA GAGCGCAGCG


 


251
CGCAATTAGG TTTCACCGGA CGCGTATTGA TACCCGTAGT AGGTTTCTTG


 


301
ATCTTGTGTG TGGCGATGGG TGCGGTCGGG ATGCTGCCCG GTATCCCGCC


 


351
GTTTTTGGAG CACTTCAAAT CTTTGGGCTA G






This corresponds to the amino acid sequence <SEQ ID 392; ORF 109>:










a109.pep




1
MYYRRVVGLS DGLGDLAAGI ERSLGRRRIL TAFGSGHGND AQRQNHPIRR


 


51
HRGVLFRLVN PVFGWALTML LDNLGLIGCK ERSAQLGFTG RVLIPVVGFL


 


101
ILCVAMGAVG MLPGIPPFLE HFKSLG*






m109/a109 97.6% identity in 126 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 393>:










g111.seq




1
ATGCCGTCTG AAACACGCCT GCCGAACCTT ATCCGCGCCT TGATATTTGC


 


51
CCTGGGTTTC ATCTTCCTGA ACGCCTGTTC GGaacaaacC GCGCAaaccg


 


101
TTACCCTGCA AGGCGAAACG ATGGGTACGA CCtATACCGT CAAATACCTT


 


151
TCAAATAATC GGGACAAACT CCCCTCCCCT GCCAAAATAC AAAAGCGCAT


 


201
TGATGATGCG CTTAAAGAAG TCAACCGGCA GATGtccaCC TACCAGACCG


 


251
ATTCCGAAAT CAGCCGGTTt atacagacan atgctggaga gctcttcgcg


 


301
tntcatgcag nttctataac tgattccgcc gaagactgtc tgcctaatac


 


351
gcctatctca tcggcgctct ga






This corresponds to the amino acid sequence <SEQ ID 394; ORF 111.ng>:










g111.pep




1
MPSETRLPNL IRALIFALGF IFLNACSEQT AQTVTLQGET MGTTYTVKYL


 


51
SNNRDKLPSP AKIQKRIDDA LKEVNRQMST YQTDSEISRF IQTAGELFAH


 


101
ASITDSAEDC LPNTPISSAL *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 395>:










m111.seq




1
ATGCCGTCTG AAACACGCCT GCCGAACTTT ATCCGCGTCT TGATATTTGC


 


51
CCTGGGTTTC ATCTTCCTGA ACGCCTGTTC GGAACAAACC GCGCAAACCG


 


101
TTACCCTGCA AGGCGAAACG ATGGGCACGA CCTATAyCGT CAAATACCTT


 


151
TCAAATAATC GGGACAAACT CCCCTCACCT GCCGAAATAC AwAAACGCAT


 


201
CGATGACGCG CTTAAAGAAk TCAACCGGyA GATGTCCACC TATCAGCCCG


 


251
ACTCCGAAAT CAGCCGGTTC AACCAACACA CAGCCGGCAA GCCCCTCCGC


 


301
ATTTCAAGCG ACTTCGCACA CGTTACTGCC GAAGCCGTCC GCCTGAACCG


 


351
CCTGACACAC GGCGCGCTGG ACGTAACCGT CGGCCCCTTG GTCAACCTTT


 


401
GGGGATTCGG CCCCGACAAA TCCGTTACCC GTGAACCGTC GCCGGAACAA


 


451
ATCAAACAGG CGGCATCTTA TACGGGCATA GACAAAATCA TTTTGAAACA


 


501
AGGCAAAGAT TACGCTTCCT TGAGCAAAAC CCACCCCAAG GCCTATTTGG


 


551
ATTTATCTTC GATTGCCAAA GGCTTCGGCG TTGATAAAGT TGCGGGCGAA


 


601
CTGGAAAAAT ACGGCATTCA AAATTATCTG GTCGAAATCG GCGGCGAGTT


 


651
GCACGGCAAA GGCAAAAACG CGCGCGGCGA ACCGTGGCGC ATCGGTATCG


 


701
AGCAGCCCAA TATCGTCCAA GGCGGCAATA CGCAGATTAT CGTCCCGCTG


 


751
AACAACCGTT CGCTTGCCAC TTCCGGCGAT TACCGTATTT TCCACGTCGA


 


801
TAAAAACGGC AAACGCCTCT CCCATATCAT CAACCCGAAC AACAAACGAC


 


851
CCATCAGCCA CAACCTCGCC TCCATCAGCG TGGTCGCAGA CAGTGCGATG


 


901
ACGGCGGACG GCTTGTCCAC AGGATTATTC GTATTGGGCG AAACCGAAGC


 


951
CTTAAAGCTG GCAGAGCGCG AAAAACTCGC TGTTTTCCTG ATTGTCAGGG


 


1001
ATAAAGGCGG cTACCGCACC GCCATGTCTT CCGAATTTGA AAAACTGcTC


 


1051
CGCTAA






This corresponds to the amino acid sequence <SEQ ID 396; ORF 111>:










m111.pep




1
MPSETRLPNF IRVLIFALGF IFLNACSEQT AQTVTLQGET MGTTYXVKYL


 


51
SNNRDKLPSP AEIXKRIDDA LKEXNRXMST YQPDSEISRF NQHTAGKPLR


 


101
ISSDFAHVTA EAVRLNRLTH GALDVTVGPL VNLWGFGPDK SVTREPSPEQ


 


151
IKQAASYTGI DKIILKQGKD YASLSKTHPK AYLDLSSIAK GFGVDKVAGE


 


201
LEKYGIQNYL VEIGGELHGK GKNARGEPWR IGIEQPNIVQ GGNTQIIVPL


 


251
NNRSLATSGD YRIFHVDKNG KRLSHIINPN NKRPISHNLA SISVVADSAM


 


301
TADGLSTGLF VLGETEALKL AEREKLAVFL IVRDKGGYRT AMSSEFEKLL


 


351
R*






ORF 111 shows 88.7% identity over a 97 aa overlap with a predicted ORF (ORF 111.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 397>:










a111.seq




1
ATGCCGTCTG AAACACGCCT GCCGAACTTT ATCCGCACCT TGATATTTGC


 


51
CCTGAGTTTT ATCTTCCTGA ACGCCTGTTC GGAACAAACC GCGCAAACCG


 


101
TTACCCTGCA AGGTGAAACG ATGGGCACGA CCTATACCGT CAAATACCTT


 


151
TCAAATAATC GGGACAAACT CCCCTCACCT GCCGAAATAC AAAAGCGCAT


 


201
CGATGACGCG CTTAAAGAAG TCAACCGGCA GATGTCCACC TATCAGCCCG


 


251
ACTCCGAAAT CAGCCGGTTC AACCAACACA CAGCCGGCAA GCCCCTCCGC


 


301
ATTTCAAGCG ACTTCGCACA CGTTACTGCC GAAGCCGTCC ACCTGAACCG


 


351
CCTGACACAC GGCGCGCTGG ACGTAACCGT CGGCCCCTTG GTCAACCTTT


 


401
GGGGATTCGG CCCCGACAAA TCCGTTACCC GTGAACCGTC GCCGGAACAA


 


451
ATCAAACAAG CAGCATCTTA TACGGGCATA GACAAAATCA TTTTGAAACA


 


501
AGGCAAAGAT TACGCTTCCT TGAGCAAAAC CCACCCCAAG GCCTATTTGG


 


551
ATTTATCTTC GATTGCCAAA GGCTTCGGCG TTGATAAAGT TGCGGGCGAA


 


601
CTGGAAAAAT ACGGCATTCA AAATTATCTG GTCGAAATCG GCGGCGAGTT


 


651
GCACGGCAAA GGCAAAAACG CGCGCGGCGA ACCTTGGCGC ATCGGCATCG


 


701
AACAGCCCAA CATCGTCCAA GGCGGCAATA CGCAGATTAT CGTCCCGCTG


 


751
AACAACCGTT CGCTTGCCAC TTCCGGCGAT TACCGTATTT TCCACGTCGA


 


801
TAAAAGCGGC AAACGCCTCT CCCATATCAT TAATCCGAAC AACAAACGAC


 


851
CCATCAGCCA CAACCTCGCC TCCATCAGCG TGGTCGCAGA CAGTGCGATG


 


901
ACGGCGGACG GCTTGTCCAC AGGATTATTC GTATTGGGCG AAACCGAAGC


 


951
CTTAAAGCTG GCAGAGCGCG AAAAACTCGC TGTTTTCCTG ATTGTCAGGG


 


1001
ATAAAGGCGG CTACCGCACC GCCATGTCTT CCGAATTTGA AAAACTGCTC


 


1051
CGCTAA






This corresponds to the amino acid sequence <SEQ ID 398; ORF 111.a>:










a111.pep




1
MPSETRLPNF IRTLIFALSF IFLNACSEQT AQTVTLQGET MGTTYTVKYL


 


51
SNNRDKLPSP AEIQKRIDDA LKEVNRQMST YQPDSEISRF NQHTAGKPLR


 


101
ISSDFAHVTA EAVHLNRLTH GALDVTVGPL VNLWGFGPDK SVTREPSPEQ


 


151
IKQAASYTGI DKIILKQGKD YASLSKTHPK AYLDLSSIAK GFGVDKVAGE


 


201
LEKYGIQNYL VEIGGELHGK GKNARGEPWR IGIEQPNIVQ GGNTQIIVPL


 


251
NNRSLATSGD YRIFHVDKSG KRLSHIINPN NKRPISHNLA SISVVADSAM


 


301
TADGLSTGLF VLGETEALKL AEREKLAVFL IVRDKGGYRT AMSSEFEKLL


 


351
R*






m111/a111 97.7% identity in 351 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 399>:










g111-1.seq




1
ATGCCGTCTG AAACACGCCT GCCGAACCTT ATCCGCGCCT TGATATTTGC


 


51
CCTGGGTTTC ATCTTCCTGA ACGCCTGTTC GGAACAAACC GCGCAAacCG


 


101
TTACCCTGCA AGGCGAAACG ATGGGTACGA CCTATACCGT CAAATACCTT


 


151
TCAAATAATC GGGACAAACT CCCCTCCCCT GCCAAAATAC AAAAGCGCAT


 


201
TGATGATGCG CTTAAAGAAG TCAACCGGCA GATGTCCACC TACCAGACCG


 


251
ATTCCGAAAT CAGCCGGTTC AACCAACACA CAGCCGGCAA GCCCCTCCGC


 


301
ATTTCAAGCG ATTTCGCACA CGTTACCGCC GAAGCCGTCC GCCTGAACCG


 


351
CCTGACTCAC GGCGCACTGG ACGTAACCGT CGGCCCTTTG GTCAACCTTT


 


401
GGGGGTTCGG CCCCGACAAA TCCGTTACCC GTGAACCGTC GCCGGAACAA


 


451
ATCAAACAGG CGGCATCTTA TACGGGCATA GACAAAATCA TTTTGCAACA


 


501
AGGCAAAGAT TACGCTTCCT TGAGCAAAAC CCACCCCAAA GCCTATTTGG


 


551
ATTTATCTTC GATTGCCAAA GGCTTCGGCG TTGATAAAGT TGCGGGCGAA


 


601
CTGGAAAAAT ACGGCATTCA AAATTATCTG GTCGAAATCG GCggcGAGTT


 


651
GCACGGCAAA GGCAAAAATG CGCACGGCGA ACCGTGGCGC ATCGGTATAG


 


701
AGCAACCCAA TATcatccaa ggcggcaata cgcAGattat cgtcccgctg


 


751
aaCaaccgtt cgcttgccac ttccggcgAT taccgtaTTT tccacgtcgA


 


801
TAAAAACGGC Aaacgccttt cccacATCAT CAATCCCAAC AACAAACGAC


 


851
CCATCAGcCA CAAcctcgcc tcCATCAgCg TGGTCTCAGA CAGTGCAATG


 


901
ACGGCGGACG GTTTATCCAC AGGATTATTT GTTTTAGGCG AAACCGAAGC


 


951
CTTAAGGCTG GCAGAACAAG AAAAACTCGC TGTTTTCCTA ATTGTCCGGG


 


1001
ATAAGGACGG CTACCGCACC GCCATGTCTT CCGAATTTGC CAAGCTGCTC


 


1051
CGCTAA






This corresponds to the amino acid sequence <SEQ ID 400; ORF 111-1.ng>:










g111-1.pep




1
MPSETRLPNL IRALIFALGF IFLNACSEQT AQTVTLQGET MGTTYTVKYL


 


51
SNNRDKLPSP AKIQKRIDDA LKEVNRQMST YQTDSEISRF NQHTAGKPLR


 


101
ISSDFAHVTA EAVRLNRLTH GALDVTVGPL VNLWGFGPDK SVTREPSPEQ


 


151
IKQAASYTGI DKIILQQGKD YASLSKTHPK AYLDLSSIAK GFGVDKVAGE


 


201
LEKYGIQNYL VEIGGELHGK GKNAHGEPWR IGIEQPNIIQ GGNTQIIVPL


 


251
NNRSLATSGD YRIFHVDKNG KRLSHIINPN NKRPISHNLA SISVVSDSAM


 


301
TADGLSTGLF VLGETEALRL AEQEKLAVFL IVRDKDGYRT AMSSEFAKLL


 


351
R*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 401>:










m111-1.seq




1
ATGCCGTCTG AAACACGCCT GCCGAACTTT ATCCGCGTCT TGATATTTGC


 


51
CCTGGGTTTC ATCTTCCTGA ACGCCTGTTC GGAACAAACC GCGCAAACCG


 


101
TTACCCTGCA AGGCGAAACG ATGGGCACGA CCTATACCGT CAAATACCTT


 


151
TCAAATAATC GGGACAAACT CCCCTCACCT GCCGAAATAC AAAAACGCAT


 


201
CGATGACGCG CTTAAAGAAG TCAACCGGCA GATGTCCACC TATCAGCCCG


 


251
ACTCCGAAAT CAGCCGGTTC AACCAACACA CAGCCGGCAA GCCCCTCCGC


 


301
ATTTCAAGCG ACTTCGCACA CGTTACTGCC GAAGCCGTCC GCCTGAACCG


 


351
CCTGACACAC GGCGCGCTGG ACGTAACCGT CGGCCCCTTG GTCAACCTTT


 


401
GGGGATTCGG CCCCGACAAA TCCGTTACCC GTGAACCGTC GCCGGAACAA


 


451
ATCAAACAGG CGGCATCTTA TACGGGCATA GACAAAATCA TTTTGAAACA


 


501
AGGCAAAGAT TACGCTTCCT TGAGCAAAAC CCACCCCAAG GCCTATTTGG


 


551
ATTTATCTTC GATTGCCAAA GGCTTCGGCG TTGATAAAGT TGCGGGCGAA


 


601
CTGGAAAAAT ACGGCATTCA AAATTATCTG GTCGAAATCG GCGGCGAGTT


 


651
GCACGGCAAA GGCAAAAACG CGCGCGGCGA ACCGTGGCGC ATCGGTATCG


 


701
AGCAGCCCAA TATCGTCCAA GGCGGCAATA CGCAGATTAT CGTCCCGCTG


 


751
AACAACCGTT CGCTTGCCAC TTCCGGCGAT TACCGTATTT TCCACGTCGA


 


801
TAAAAACGGC AAACGCCTCT CCCATATCAT CAACCCGAAC AACAAACGAC


 


851
CCATCAGCCA CAACCTCGCC TCCATCAGCG TGGTCGCAGA CAGTGCGATG


 


901
ACGGCGGACG GCTTGTCCAC AGGATTATTC GTATTGGGCG AAACCGAAGC


 


951
CTTAAAGCTG GCAGAGCGCG AAAAACTCGC TGTTTTCCTG ATTGTCAGGG


 


1001
ATAAAGGCGG CTACCGCACC GCCATGTCTT CCGAATTTGA AAAACTGCTC


 


1051
CGCTAA






This corresponds to the amino acid sequence <SEQ ID 402; ORF 111-1>:










m111-1.pep




1
MPSETRLPNF IRVLIFALGF IFLNACSEQT AQTVTLQGET MGTTYTVKYL


 


51
SNNRDKLPSP AEIQKRIDDA LKEVNRQMST YQPDSEISRF NQHTAGKPLR


 


101
ISSDFAHVTA EAVRLNRLTH GALDVTVGPL VNLWGFGPDK SVTREPSPEQ


 


151
IKQAASYTGI DKIILKQGKD YASLSKTHPK AYLDLSSIAK GFGVDKVAGE


 


201
LEKYGIQNYL VEIGGELHGK GKNARGEPWR IGIEQPNIVQ GGNTQIIVPL


 


251
NNRSLATSGD YRIFHVDKNG KRLSHIINPN NKRPISHNLA SISVVADSAM


 


301
TADGLSTGLF VLGETEALKL AEREKLAVFL IVRDKGGYRT AMSSEFEKLL


 


351
R*






m111-1/g111-1 96.6% identity in 351 aa overlap





g111-1/p44550








sp|P44550|YOJL_HAEIN HYPOTHETICAL


LIPOPROTEIN HI0172 PRECURSOR >gi|1074292|pir||C64144


hypothetical protein HI0172 - Haemophilus influenzae (strain Rd KW20)


>gi|1573128 (U32702)


lipoprotein, putative [Haemophilus influenzae Rd] Length = 346


Score = 349 bits (885), Expect = 2e−95


Identities = 177/328 (53%), Positives = 240/328 (72%), Gaps = 4/328 (1%)











Query:
23
LNACSEQTAQ TVTLQGETMG TTYXVKYLSN NRDKLPSPAE IXKRIDDALK EXNRXMSTYQ
82





L AC ++T + ++L G+TMGTTY VKYL +      S  +  + I+  LK+ N  MSTY+


Sbjct:
17
LAACQKET-KVISLSGKTMGTTYHVKYLDDGSITATS-EKTHEEIEAILKDVNAKMSTYK
74


 


Query:
83
PDSEISRFNQHT-AGKPLRISSDFAHVTAEAVRLNRLTHGALDVTVGPLVNLWGFGPDKS
141




 DSE+SRFNQ+T    P+ IS+DFA V AEA+RLN++T GALDVTVGP+VNLWGFGP+K


Sbjct:
75
KDSELSRFNQVNTQVNTPIEISADFAKVLAEAIRLNKVTEGALDVTVGPVVNLWGFGPEKR
134


 


Query:
142
VTREPSPEQIKQAASYTGIDKIILKQGKDYASLSKTHPKAYLDLSSIAKGFGVDKVAGEL
201




  ++P+PEQ+ +  ++ GIDKI L   K+ A+LSK  P+ Y+DLSSIAKGFGVD+VA +L


Sbjct:
135
PEKQPTPEQLAERQAWVGIDKITLDTNKEKATLSKALPQVYVDLSSIAKGFGVDQVAEKL
194


 


Query:
202
EKYGIQNYLVEIGGELHGKGKNARGEPWRIGIEQPNIVQGGNTQIIVPLNNRSLATSGDY
261




E+   QNY+VEIGGE+  KGKN  G+PW+I IE+P        + ++ LNN  +A+SGDY


Sbjct:
195
EQLNAQNYMVEIGGEIRAKGKNIEGKPWQIAIEKPTTTGERAVEAVIGLNNMGMASSGDY
254


 


Query:
262
RIFHVDKNGKRLSHIINPNNKRPISHNLASISVVADSAMTADGLSTGLFVLGETEALKLA
321




RI+  ++NGKR +H I+P    PI H+LASI+V+A ++MTADGLSTGLFVLGE +AL++A


Sbjct:
255
RIY-FEENGKRFAHEIDPKTGYPIQHHLASITVLAPTSMTADGLSTGLFVLGEDKALEVA
313


 


Query:
322
EREKLAVFLIVRDKGGYRTAMSSEFEKL 349




E+  LAV+LI+R   G+ T  SS F+KL


Sbjct:
314
EKNNLAVYLIIRTDNGFVTKSSSAFKKL 341






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 403>:










a111-1.seq




1
ATGCCGTCTG AAACACGCCT GCCGAACTTT ATCCGCACCT TGATATTTGC


 


51
CCTGAGTTTT ATCTTCCTGA ACGCCTGTTC GGAACAAACC GCGCAAACCG


 


101
TTACCCTGCA AGGTGAAACG ATGGGCACGA CCTATACCGT CAAATACCTT


 


151
TCAAATAATC GGGACAAACT CCCCTCACCT GCCGAAATAC AAAAGCGCAT


 


201
CGATGACGCG CTTAAAGAAG TCAACCGGCA GATGTCCACC TATCAGCCCG


 


251
ACTCCGAAAT CAGCCGGTTC AACCAACACA CAGCCGGCAA GCCCCTCCGC


 


301
ATTTCAAGCG ACTTCGCACA CGTTACTGCC GAAGCCGTCC ACCTGAACCG


 


351
CCTGACACAC GGCGCGCTGG ACGTAACCGT CGGCCCCTTG GTCAACCTTT


 


401
GGGGATTCGG CCCCGACAAA TCCGTTACCC GTGAACCGTC GCCGGAACAA


 


451
ATCAAACAAG CAGCATCTTA TACGGGCATA GACAAAATCA TTTTGAAACA


 


501
AGGCAAAGAT TACGCTTCCT TGAGCAAAAC CCACCCCAAG GCCTATTTGG


 


551
ATTTATCTTC GATTGCCAAA GGCTTCGGCG TTGATAAAGT TGCGGGCGAA


 


601
CTGGAAAAAT ACGGCATTCA AAATTATCTG GTCGAAATCG GCGGCGAGTT


 


651
GCACGGCAAA GGCAAAAACG CGCGCGGCGA ACCTTGGCGC ATCGGCATCG


 


701
AACAGCCCAA CATCGTCCAA GGCGGCAATA CGCAGATTAT CGTCCCGCTG


 


751
AACAACCGTT CGCTTGCCAC TTCCGGCGAT TACCGTATTT TCCACGTCGA


 


801
TAAAAGCGGC AAACGCCTCT CCCATATCAT TAATCCGAAC AACAAACGAC


 


851
CCATCAGCCA CAACCTCGCC TCCATCAGCG TGGTCGCAGA CAGTGCGATG


 


901
ACGGCGGACG GCTTGTCCAC AGGATTATTC GTATTGGGCG AAACCGAAGC


 


951
CTTAAAGCTG GCAGAGCGCG AAAAACTCGC TGTTTTCCTG ATTGTCAGGG


 


1001
ATAAAGGCGG CTACCGCACC GCCATGTCTT CCGAATTTGA AAAACTGCTC


 


1051
CGCTAA






This corresponds to the amino acid sequence <SEQ ID 404; ORF 111-1.a>:










a111-1.pep




1
MPSETRLPNF IRTLIFALSF IFLNACSEQT AQTVTLQGET MGTTYTVKYL


 


51
SNNRDKLPSP AEIQKRIDDA LKEVNRQMST YQPDSEISRF NQHTAGKPLR


 


101
ISSDFAHVTA EAVHLNRLTH GALDVTVGPL VNLWGFGPDK SVTREPSPEQ


 


151
IKQAASYTGI DKIILKQGKD YASLSKTHPK AYLDLSSIAK GFGVDKVAGE


 


201
LEKYGIQNYL VEIGGELHGK GKNARGEPWR IGIEQPNIVQ GGNTQIIVPL


 


251
NNRSLATSGD YRIFHVDKSG KRLSHIINPN NKRPISHNLA SISVVADSAM


 


301
TADGLSTGLF VLGETEALKL AEREKLAVFL IVRDKGGYRT AMSSEFEKLL


 


351
R*






a111-1/m111-1 98.9% identity in 351 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 405>:










g114.seq




1
ATGGCTTCCA TCACTTCGCC GCTGCACGGG GCGCAGCAGG AATGCAGCAA


 


51
GACTTTTTTA TGTCCGCCGG GCGGGACGAG TATGGGGCGG TCAATGTCGG


 


101
TAACGGTAGG TTTGTTTTGT GTTTCCATTA ACTTAACAAT ATCTGTCGAA


 


151
TACGGTCAAA GCGGCTATTT TACCAGAGCC GCCGAATGTA AAACAGGGTG


 


201
TCAGGGCATC AGCCCGAGCT GCCTGAACGA ACGGACGGTT TGCGAGGTAA


 


251
CGATAAAATG GTCGAGCAGC GAAACATCAA CCAGCGACAT GGCCTGTGCC


 


301
AGCCGCCTTG TGAACATGAT GTCTTCCTGC GAAGGTTCAG GCGAGCCGCC


 


351
CGGATGGTTG TGCGCGATAA TCAGGCTGTC GGCATATTCG TCCAATGCCA


 


401
GTTTGACGAT TTCGCGGATG TAA






This corresponds to the amino acid sequence <SEQ ID 406; ORF 114.ng>:










g114.pep




1
MASITSPLHG AQQECSKTFL CPPGGTSMGR SMSVTVGLFC VSINLTISVE


 


51
YGQSGYFTRA AECKTGCQGI SPSCLNERTV CEVTIKWSSS ETSTSDMACA


 


101
SRLVNMMSSC EGSGEPPGWL CAIIRLSAYS SNASLTISRM *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 407>:










m114.seq




1
ATGGCTTCCA TCACTTCGCC GCTGCACGGG GCGCACAGAG AATGCAGCAA


 


51
GACTTTTTTA TGTCCACCGG GCGGGACGAG TATAGGGCGG TCAATGTCGG


 


101
TAACGGTAGG TTTGTTTTGT GTTTCCATTA ACTTAACAAT ATCTGTTGAA


 


151
TACGGTTGAA GCGGCTATTT TATCAGAGCC GCCGCATGTA AAACAGAGTG


 


201
TCAGGGCATC AACCCGAGCT GTCTGAACGA ACAGACGCTT TGCGAkGTAA


 


251
CGATAAAATG GTCGAGCAGC GACACATCGA CCAGCGACAT TGCCTGTGCC


 


301
AGCCGCCTTG TGAACATGAT GTCTTCCTGC GAArGTTCsG GCGAGCCGcC


 


351
CGgATGGTTG TGCGCAATAA TCAGGCTGTC GGCATATTCG TCCAATGCCA


 


401
GTTTGACGAT TTCGCGGATG TAA






This corresponds to the amino acid sequence <SEQ ID 408; ORF 114>:










m114.pep




1
MASITSPLHG AHRECSKTFL CPPGGTSIGR SMSVTVGLFC VSINLTISVE


 


51
YGXSGYFIRA AACKTECQGI NPSCLNEQTL CXVTIKWSSS DTSTSDIACA


 


101
SRLVNMMSSC EXSGEPPGWL CAIIRLSAYS SNASLTISRM *






m114/g114 90.0% identity over a 140 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 409>:










a114.seq




1
ATGCCGGAGG CAAGCATCGC CTCCATCACT TCGCCGCTGC ACGGGGCGCA


 


51
ACAGGAATGC AGCAAGACTT TTTTATGTCC GCCGGGCGGG ACGAGTATGG


 


101
GGCGGTCAAT GTCGGTAACG GTAGGTTTGT TTTGTGTTTC CATTAACTTA


 


151
ACGATATCTG TCGAATACGG TTGAAGCGGC TATTTTATCA GAGCCGCCGC


 


201
ATGTAAAACA GGGTGTCAGG GCATCAGCCC GAGCTGCCTG AACGAACGGA


 


251
CGGTTTGCGC CGTTACGATA AAATGGTCGA GCAGCGACAC ATCGACCAGC


 


301
GACATTGCCT GTGCCAGCCG CCTTGTGAAC ATGATGTCTT CCTGCGAAGG


 


351
TTCGGGCGAG CCGCCCGGAT GGTTGTGCGC GATAATCAGG CTGTCGGCAT


 


401
ATTCGTCCAA TGCCAGTTTG ACAATTTCAC GGATGTAA






This corresponds to the amino acid sequence <SEQ ID 410; ORF 114.a>:










a114.pep




1
MPEASIASIT SPLHGAQQEC SKTFLCPPGG TSMGRSMSVT VGLFCVSINL


 


51
TISVEYG*SG YFIRAAACKT GCQGISPSCL NERTVCAVTI KWSSSDTSTS


 


101
DIACASRLVN MMSSCEGSGE PPGWLCAIIR LSAYSSNASL TISRM*






m114/a114 92.9% identity in 140 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 411>:










g117.seq




1
atggtcgacg aactcgacCT GCTGCCCGAT GCCGTCGCCG CCACCCTGCT


 


51
TGCCGACATC GGACGCTACG TCCCCGATTG GAACCTATTG GTTTCCGAGC


 


101
GCTGCAACAG CACCGTCGCC GAGCTGGTCA AAGGTGtgga CGAAGTGCAG


 


151
AAACTTACCC ACTTCGCCCG GGTGGACAGC CTCGCCACGC CGGAAGAACG


 


201
CGCACAGCAA GCGGAAACCA TGCGGAAAAT GCTGCTGGCg atggttaccg


 


251
Acatccgcgt cgtaTTAATC AAACTGGCGA TGCGTacgcg caccCTGcta


 


301
ttTTtaaGCA ACGCCCCCGA CAGCCCTGAA AAACgcgccG TCgccaaAga


 


351
aacccTCGAC ATCTTCGCCC CGCTCGCCAA CCGCTTGGGC GTGTGGCAGC


 


401
TCAAATGGCA GCTCGAAGAT TTGGGCTTCC GCCATCAAGA ACCCGAAAAA


 


451
TACCGCGAAA TCGCCCTGCT TTTGGACGAA AAACGCACCG AACGCCTCGA


 


501
ATACATCGAA AACTTCCTCG ATATCCTGCG TACGGAACTC AAAAAATACA


 


551
ATATCCACTT TGAAGTCGCC GGCCGTCCGA AACACATCTA CTCCATTTAC


 


601
AAAAAAATGG TGAAGAAAAA ACTCAGCTTC GACGgccTGT TCGACATCCG


 


651
CGCCGTGCGG ATTCTGGTCG ATACCGTCCC CGaGTGTTAC ACCACGCTGG


 


701
gcaTCGTCCA CAGCCTCTGG CAGCCCATTC CCGGCGagtt CGAcgactAC


 


751
ATCGCCAACC CCAAAGgcaA CGgttATAAA AGtTTGCACA CCGTCATCGT


 


801
cggcccGGAa gacaaaggtg tggaaGtgCA AATCCGCACC TTCGAtatGC


 


851
accAATTCaa CgaatTcggT gtcgccgCCC ACTGGCGtta caaagaaggc


 


901
ggcaaaggcg attccGCCtA cgaacaaAAA ATcgccTggt TGCgccaACT


 


951
CTTGGACTGG CGCGAAAATA TGGCGGAAAG CGGCAAGGAA GACCTCGCCG


 


1001
CCGCCTTCAA AACCGAGCTT TTCAACGACA CGATTTATGT TTTGACCCCG


 


1051
CACGGCAAAG TCCTCTCTCT GCCAACGGGC GCAACCCCCA TCGACTTCGC


 


1101
CTACGCCCTG CACAGCAGCA TcggCGACCG CTGCCGGGGC GCGAAAGTCG


 


1151
AaggGCAGAT TGTGCCGCTG TCCACCCCGC TCGAAAACGG ACAGCGCGTC


 


1201
GAAATcatta cCGCcaaAGA AGGGCATCCT TCCGTCAACT GGCTTTACGA


 


1251
AGGctgGGtc aAATCCGGCA AGGCCATCGG caaAATCCGC GCCTAcatCC


 


1301
GCCAGcaaAa cgCcgaCACC GTGCGCGAAG AAGGCCGTGT CCAACTCGAC


 


1351
AAGCAGCTTG CCAAACTCAC GCCCAAACCC AACCTGCAAG AGCTTgccga


 


1401
aaATCTCGGC tacaaAAAGC cagaagacct ctacacCGCc gtcggacaag


 


1451
gcgaaatttc caaccgcgcc atCcaaaaag cctgcggcac GCTgaacgaa


 


1501
ccgccccCCG TGCCCGTCAG CGCAACCACC ATCGTCAAAC AGTCCAAAAT


 


1551
CAAAAAAGGT GGCAAAACCG GCGTGCTCAT CGACGGCGAA GACGGCTTGA


 


1601
TGACCACGCT TGCCAAATGC TGCAAACCCG CGCCGCCCGA CGATATTGCC


 


1651
GGCTTCGTTA CCCGCGAGCG CGGCATTTCC GTCCACCGCA AAACCTGCCC


 


1701
CTCTTTCCGA CACCTTGCCG AACACGCGCC CGAAAAAGTA CTGGACGCAA


 


1751
GTTGGGCGGC GTTGCAGGAA GGGCAAGTGT TCGCCGTCGA TATCGAAATC


 


1801
CGCGCCCAAG ACCGCTCCGG GCTTTTGCGC GACGTATCCG ACGCGCTCGC


 


1851
CCGCCACAAA CTCAACGTTA CCGCCGTGCA AACCCAGTCC CGCGACTTGG


 


1901
AAGCCAGCAT GAGGTTCACG CTCGAAGTCA AACAAGtCAA CGacCTCCCG


 


1951
CGCGTCCTCG CCGGCCTCGG CGATGTCAAA GGCGTATTGA GCGTTACCCG


 


2001
GCTTTAA






This corresponds to the amino acid sequence <SEQ ID 412; ORF 117.ng>:










g117.pep




1
MVDELDLLPD AVAATLLADI GRYVPDWNLL VSERCNSTVA ELVKGVDEVQ


 


51
KLTHFARVDS LATPEERAQQ AETMRKMLLA MVTDIRVVLI KLAMRTRTLL


 


101
FLSNAPDSPE KRAVAKETLD IFAPLANRLG VWQLKWQLED LGFRHQEPEK


 


151
YREIALLLDE KRTERLEYIE NFLDILRTEL KKYNIHFEVA GRPKHIYSIY


 


201
KKMVKKKLSF DGLFDIRAVR ILVDTVPECY TTLGIVHSLW QPIPGEFDDY


 


251
IANPKGNGYK SLHTVIVGPE DKGVEVQIRT FDMHQFNEFG VAAHWRYKEG


 


301
GKGDSAYEQK IAWLRQLLDW RENMAESGKE DLAAAFKTEL FNDTIYVLTP


 


351
HGKVLSLPTG ATPIDFAYAL HSSIGDRCRG AKVEGQIVPL STPLENGQRV


 


401
EIITAKEGHP SVNWLYEGWV KSGKAIGKIR AYIRQQNADT VREEGRVQLD


 


451
KQLAKLTPKP NLQELAENLG YKKPEDLYTA VGQGEISNRA IQKACGTLNE


 


501
PPPVPVSATT IVKQSKIKKG GKTGVLIDGE DGLMTTLAKC CKPAPPDDIA


 


551
GFVTRERGIS VHRKTCPSFR HLAEHAPEKV LDASWAALQE GQVFAVDIEI


 


601
RAQDRSGLLR DVSDALARHK LNVTAVQTQS RDLEASMRFT LEVKQVNDLP


 


651
RVLAGLGDVK GVLSVTRL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 413>:









m117.seq (partial)










1
..GTGAAACTCA AGAAATACAA TGTCCATTTC GAAGTCGCCG GCCGCCCGAA



 


51
  ACACATCTAC TCCATTTACA AAAAAATGGT GAAGAAAAAA CTCAGCTTCG


 


101
  ACGGCCTCTT TGACATCCGC GCCGTGCGAA TTCTGGTTGA TACCGTCCCC


 


151
  GAGTGTTACA CCACGCTGGG TATCGTCCAC AGCCTCTGGC AGCCCATTCC


 


201
  CGGCGAGTTC GACGACTACA TCGCCAATCC CAAAGGCAAC GGCTATAAAA


 


251
  GTTTGCACAC CGTCATCGTC GGCCCGGAAG ACAAAGGCGT GGAAGTACAA


 


301
  ATCCGCACCT TCGATATGCA CCAATTCAAC GAATTCGGTG TCGCCGCCCA


 


351
  CTGgCGTTAC AAAGAGGGCG GCAAGGGCGA TTCCGCCTAC GAACAGAAAA


 


401
  TCGCCTGGTT GCGCCAACTC TTGGACTGGC GCGAAAACAT GGCGGAAAGC


 


451
  GGCAAGGAAG ACCTCGCCGC CGCCTTCAAA ACCGAGCTTT TCAACGACAC


 


501
  GATTTATGTT TTGACCCCGC ACGGCAAAGT CCTCTCCCTG CCCACGGGCG


 


551
  CGACCCCCAT CGACTTCGCC TACGCCCTGC ACAGCAGCAT CGGCGACCGT


 


601
  TGCCGCGGTG CGAAAGTCGA AGGGCAGATT GTGCCGCTGT CCACCCCGCT


 


651
  CGAAAACGGA CAGCGCGTCG AAATCATTAC CGCCAAAGAA GGGCATCCTT


 


701
  CCGTCAACTG GCTTTACGAA GGCTGGGTCA AATCCAACAA GGCAATCGGC


 


751
  AAAATCCGCG CCTACATCCG CCAGCAAAAC GCCGACACCG TGCGCGAAGA


 


801
  AGGCCGCGTC CAACTCGACA AACAGCTTGC CAAACTCACG CCCAAACCCA


 


851
  ACCTGCAAGA GCTTGCCGAA AATCTCGGCT ACAAAAAGCC AGAAGACCTC


 


901
  TACACCGCCG TCGGACAAGG CGAAATTTCC AACCGCGCCA TCCAAAAAGC


 


951
  CTGCGGCACg CTGAACGAAC CGCCGCCCGT ACCCGTCAGC GAAACCACCA


 


1001
  TCGTCAAACA GTCCAAAATC AAAAAAGGCG GCAAAAACGG CGTGCTCATC


 


1051
  GACGGCGAAG ACGGTCTGAT GACCACGCTT GCCAAATGCT GCAAACCCGC


 


1101
  GCCGCCCGAC GATATTATCG GCTTCGTTAC CCGCGAGCGC GgCATTTCAG


 


1151
  TGCACCGCAA AwyyTkCyCG TCTTTCCAAC ACCTCGCCGA ACACGCGCCC


 


1201
  GAwAAAGTGC TGGACGCAAG CTGGGCGGCA TTGCAGGAAG GACAAGTATT


 


1251
  CGCCGTCGAT ATCGAAATCC GCGCCCAAGA CCGCTCCGGG CTTTTGCGCG


 


1301
  ACGTATCCGA CGCGCTCGCC CGCCACAAAC TCAACGTTAC CGCCGTGCAA


 


1351
  ACCCAGTCCC GCGACTTGGA AGCCAGCATG AGGTTCACGC TCGAAGTCAA


 


1401
  ACAAGTCAAC GACCTCCCGC GCGTCCTCGC CAGCCTCGGC GACGTCAAAG


 


1451
  GCGTATTGAG CGTTACCCGG CTTTAA






This corresponds to the amino acid sequence <SEQ ID 414; ORF 117>:









m117.pep (partial)










1
....VKLKKYNVHF EVAGRPKHIY SIYKKMVKKK LSFDGLFDIR AVRILVDTVP



 


51
    ECYTTLGIVH SLWQPIPGEF DDYIANPKGN GYKSLHTVIV GPEDKGVEVQ


 


101
    IRTFDMHQFN EFGVAAHWRY KEGGKGDSAY EQKIAWLRQL LDWRENMAES


 


151
    GKEDLAAAFK TELFNDTIYV LTPHGKVLSL PTGATPIDFA YALHSSIGDR


 


201
    CRGAKVEGQI VPLSTPLENG QRVEIITAKE GHPSVNWLYE GWVKSNKAIG


 


251
    KIRAYIRQQN ADTVREEGRV QLDKQLAKLT PKPNLQELAE NLGYKKPEDL


 


301
    YTAVGQGEIS NRAIQKACGT LNEPPPVPVS ETTIVKQSKI KKGGKNGVLI


 


351
    DGEDGLMTTL AKCCKPAPPD DIIGFVTRER GISVHRKXXX SFQHLAEHAP


 


401
    XKVLDASWAA LQEGQVFAVD IEIRAQDRSG LLRDVSDALA RHKLNVTAVQ


 


451
    TQSRDLEASM RFTLEVKQVN DLPRVLASLG DVKGVLSVTR L*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 117 shows 97.6% identity over a 490 aa overlap with a predicted ORF (ORF 117.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 415>:










a117.seq




1
ATGGTTCATG AACTCGACCT GCTCCCCGAT GCCGTCGCCG CCACCCTGCT


 


51
TGCCGACATC GGACGCTACG TCCCCGACTG GAACCTATTG GTTTCCGAAC


 


101
GCTGCAACAG TACCGTCGCC GAGCTGGTCA AAGGTGTGGA CGAAGTGCAG


 


151
AAACTCACCC ACTTCGCCCG GGTGGACAGC CTCGCCACGC CGGAAGAACG


 


201
CGCCCAGCAG GCAGAAACTA TGCGGAAAAT GCTGCTGGCG ATGGTTACCG


 


251
ACATCCGCGT CGTGTTAATC AAACTGGCGA TGCGTACGCG CACCCTGCAA


 


301
TTTTTAAGCA ACGCCCCCGA CAGCCCCGAA AAACGCGCCG TCGCCAAAGA


 


351
AACCCTCGAC ATCTTCGCCC CGCTCGCCAA CCGTTTGGGC GTGTGGCAGC


 


401
TCAAATGGCA GCTCGAAGAT TTGGGCTTCC GCCATCAAGA ACCCGAAAAA


 


451
TACCGCGAAA TCGCCCTGCT TTTGGACGAA AAACGCACCG AACGCCTCGA


 


501
ATACATCGAA AACTTCCTTA ATATCCTGCG TACGGAACTC AAAAAATACA


 


551
ATATCCACTT TGAAGTCGCC GGCCGTCCGA AACACATCTA CTCCATTTAC


 


601
AAAAAAATGG TGAAGAAAAA ACTCAGCTTC GACGGGTTGT TCGACATCCG


 


651
CGCCGTGCGG ATTCTGGTTG ATACCGTCCC CGAGTGTTAC ACCACACTGG


 


701
GCATTGTCCA CAGCCTCTGG CAGCCCATTC CCGGCGAGTT CGACGACTAC


 


751
ATCGCCAACC CGAAAGGCAA CGGCTATAAA AGTTTGCACA CCGTCATCGT


 


801
CGGCCCGGAA GACAAAGGCG TGGAAGTGCA AATCCGCACC TTCGATATGC


 


851
ACCAATTCAA CGAATTCGGT GTCGCCGCGC ACTGGCGTTA CAAAGAGGGC


 


901
GGCAAAGGCG ATTCCGCCTA CGAACAAAAA ATCGCCTGGT TACGCCAACT


 


951
TTTGGACTGG CGCGAAAACA TGGCGGAAAG CGGCAAGGAA GACCTCGCCG


 


1001
CCGCCTTCAA AACCGAGCTT TTCAACGACA CGATTTATGT TTTGACCCCG


 


1051
CACGGCAAAG TCCTCTCCCT GCCCACAGGC GCGACCCCCA TCGACTTCGC


 


1101
CTACGCCCTG CACAGCAGCA TCGGCGACCG TTGCCGCGGT GCGAAAGTCG


 


1151
AAGGGCAGAT TGTGCCGCTG TCCACCCCGC TCGAAAACGG ACAGCGTGTC


 


1201
GAAATCATTA CCGCCAAAGA AGGGCATCCT TCCGTCAACT GGCTTTACGA


 


1251
AGGCTGGGTC AAATCCAACA AGGCAATCGG CAAAATCCGC GCCTACATCC


 


1301
GCCAGCAAAA CGCCGACACC GTGCGCGAAG AAGGCCGCGT CCAACTCGAC


 


1351
AAACAGCTTG CCAAACTCAC GCCCAAACCC AACCTGCAAG AGCTTGCCGA


 


1401
AAATCTCGGC TACAAAAAGC CAGAAGACCT CTACACCGCC GTCGGACAAG


 


1451
GCGAAATTTC CAACCGCGCC ATCCAAAAAG CCTGCGGCAC GCTGAACGAA


 


1501
CCGCCGCCCG TACCCGTCAG CGAAACCACC ATCGTCAAAC AGTCCAAAAT


 


1551
CAAAAAAGGC GGCAAAAACG GCGTGCTCAT CGACGGCGAA GACGGTCTGA


 


1601
TGACCACGCT TGCCAAATGC TGCAAACCCG CGCCGCCCGA CGACATTGTC


 


1651
GGCTTCGTTA CCCGCGATCG CGGCATTTCG GTACACCGCA AAACCTGCCC


 


1701
CTCTTTCCGA CACCTCGCCG AACACGCGCC CGAAAAAGTA CTGGACGCAA


 


1751
GTTGGGCGGC GTTGCAGGAA GGACAAGTGT TCGCCGTCGA TATCGAAATC


 


1801
CGCGCCCAAG ACCGCTCCGG GCTTTTGCGC GACGTATCCG ACGCGCTCGC


 


1851
CCGCCACAAA CTCAACGTTA CCGCCGTGCA AACCCAGTCC CGCGACTTGG


 


1901
AAGCCAGCAT GAGGTTCACG CTCGAAGTCA AACAAGTTAC CGACCTCCCA


 


1951
CGCGTCCTCG CCAGCCTCGG CGACGTCAAA GGCGTATTGA GCGTTACCCG


 


2001
GCTTTAA






This corresponds to the amino acid sequence <SEQ ID 416; ORF 117.a>:










a117.pep




1
MVHELDLLPD AVAATLLADI GRYVPDWNLL VSERCNSTVA ELVKGVDEVQ


 


51
KLTHFARVDS LATPEERAQQ AETMRKMLLA MVTDIRVVLI KLAMRTRTLQ


 


101
FLSNAPDSPE KRAVAKETLD IFAPLANRLG VWQLKWQLED LGFRHQEPEK


 


151
YREIALLLDE KRTERLEYIE NFLNILRTEL KKYNIHFEVA GRPKHIYSIY


 


201
KKMVKKKLSF DGLFDIRAVR ILVDTVPECY TTLGIVHSLW QPIPGEFDDY


 


251
IANPKGNGYK SLHTVIVGPE DKGVEVQIRT FDMHQFNEFG VAAHWRYKEG


 


301
GKGDSAYEQK IAWLRQLLDW RENMAESGKE DLAAAFKTEL FNDTIYVLTP


 


351
HGKVLSLPTG ATPIDFAYAL HSSIGDRCRG AKVEGQIVPL STPLENGQRV


 


401
EIITAKEGHP SVNWLYEGWV KSNKAIGKIR AYIRQQNADT VREEGRVQLD


 


451
KQLAKLTPKP NLQELAENLG YKKPEDLYTA VGQGEISNRA IQKACGTLNE


 


501
PPPVPVSETT IVKQSKIKKG GKNGVLIDGE DGLMTTLAKC CKPAPPDDIV


 


551
GFVTRDRGIS VHRKTCPSFR HLAEHAPEKV LDASWAALQE GQVFAVDIEI


 


601
RAQDRSGLLR DVSDALARHK LNVTAVQTQS RDLEASMRFT LEVKQVTDLP


 


651
RVLASLGDVK GVLSVTRL*






m117/a117 98.0% identity in 490 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 417>:










g117-1.seq




1
ATGACCGCCA TCAGCCCGAT TCAAGACACG CAAAGCGCGA CCCTGCAAGA


 


51
ATTGCGCGAA TGGTTCGACA GCTACTGCGC CGCTCTGCCG GACAACGATA


 


101
AAAACCTCAT CGGTACCGCA TGGTCGCTGG CGCAGGAACA TTATCCTGCC


 


151
GATGCCGCCA CGCCGTATGG CGAGCCGCTG CCCGACCACT TCCTCGGCGC


 


201
GGCGCAAATG GTCGACGAAC TCGACCTGCT GCCCGATGCC GTCGCCGCCA


 


251
CCCTGCTTGC CGACATCGGA CGCTACGTCC CCGATTGGAA CCTATTGGTT


 


301
TCCGAGCGCT GCAACAGCAC CGTCGCCGAG CTGGTCAAAG GTGTGGACGA


 


351
AGTGCAGAAA CTTACCCACT TCGCCCGGGT GGACAGCCTC GCCACGCCGG


 


401
AAGAACGCGC ACAGCAAGCG GAAACCATGC GGAAAATGCT GCTGGCGATG


 


451
GTTACCGACA TCCGCGTCGT ATTAATCAAA CTGGCGATGC GTACGCGCAC


 


501
CCTGCAATTT TTAAGCAACG CCCCCGACAG CCCTGAAAAA CGCGCCGTCG


 


551
CCAAAGAAAC CCTCGACATC TTCGCCCCGC TCGCCAACCG CTTGGGCGTG


 


601
TGGCAGCTCA AATGGCAGCT CGAAGATTTG GGCTTCCGCC ATCAAGAACC


 


651
CGAAAAATAC CGCGAAATCG CCCTGCTTTT GGACGAAAAA CGCACCGAAC


 


701
GCCTCGAATA CATCGAAAAC TTCCTCGATA TCCTGCGTAC GGAACTCAAA


 


751
AAATACAATA TCCACTTTGA AGTCGCCGGC CGTCCGAAAC ACATCTACTC


 


801
CATTTACAAA AAAATGGTGA AGAAAAAACT CAGCTTCGAC GGCCTGTTCG


 


851
ACATCCGCGC CGTGCGGATT CTGGTCGATA CCGTCCCCGA GTGTTACACC


 


901
ACGCTGGGCA TCGTCCACAG CCTCTGGCAG CCCATTCCCG GCGagttCGA


 


951
cgactACATC GCCAACCCCA AAGgcaACGg ttATAAAAGt TTGCACACCG


 


1001
TCATCGTcgg cccGGAagaa aaaggtgtgg aagtgcAAAT CCGCACCTTC


 


1051
GATATGCacc AATTCaaCga ATTCGGTGTC GCCGCCCACT GGCGTTACAA


 


1101
AGAAGGCGGC AAAGGCGATT CCGCCTACGA ACAAAAAATC GCCTGGTTGC


 


1151
GCCAACTCTT GGACTGGCGC GAAAATATGG CGGAAAGCGG CAAGGAAGAC


 


1201
CTCGCCGCCG CCTTCAAAAC CGAGCTTTTC AACGACACGA TTTATGTTTT


 


1251
GACCCCGCAC GGCAAAGTCC TCTCTCTGCC AACGGGCGCA ACCCCCATCG


 


1301
ACTTCGCCTA CGCCCTGCAC AGCAGCATCG GCGACCGCTG CCGGGGCGCG


 


1351
AAAGTCGAAG GGCAGATTGT GCCGCTGTCC ACCCCGCTCG AAAACGGACA


 


1401
GCGCGTCGAA ATCATTACCG CCAAAGAAGG GCATCCTTCC GTCAACTGGC


 


1451
TTTACGAAGG CTGGGTCAAA TCCGGCAAGG CCATCGGCAA AATCCGCGCC


 


1501
TACATCCGCC AGCAAAACGC CGACACCGTG CGCGAAGAAG GCCGTGTCCA


 


1551
ACTCGACAAG CAGCTTGCCA AACTCACGCC CAAACCCAAC CTGCAAGAGC


 


1601
TTGCCGAAAA TCTCGGCTAC AAAAAGCCAG AAGACCTCTA CACCGCCGTC


 


1651
GGACAAGGCG AAATTTCCAA CCGCGCCATC CAAAAAGCCT GCGGCACGCT


 


1701
GAACGAACCG CCGCCCGTGC CCGTCAGCGC AACCACCATC GTCAAACAGT


 


1751
CCAAAATCAA AAAAGGTGGC AAAACCGGCG TGCTCATCGA CGGCGAAGAC


 


1801
GGCTTGATGA CCACGCTTGC CAAATGCTGC AAACCCGCGC CGCCCGACGA


 


1851
TATTGCCGGC TTCGTTACCC GCGAGCGCGG CATTTCCGTC CACCGCAAAA


 


1901
CCTGCCCCTC TTTCCGACAC CTTGCCGAAC ACGCGCCCGA AAAAGTACTG


 


1951
GACGCAAGTT GGGCGGCGTT GCAGGAAGGG CAAGTGTTCG CCGTCGATAT


 


2001
CGAAATCCGC GCCCAAGACC GCTCCGGGCT TTTGCGCGAC GTATCCGACG


 


2051
CGCTCGCCCG CCACAAACTC AACGTTACCG CCGTGCAAAC CCAGTCCCGC


 


2101
GACTTGGAAG CCAGCATGAG GTTCACGCTC GAAGTCAAAC AAGTCAACGA


 


2151
CCTCCCGCGC GTCCTCGCCG GCCTCGGCGA TGTCAAAGGC GTATTGAGCG


 


2201
TTACCCGGCT TTAA






This corresponds to the amino acid sequence <SEQ ID 418; ORF 117-1.ng>:










g117-1.pep




1
MTAISPIQDT QSATLQELRE WFDSYCAALP DNDKNLIGTA WSLAQEHYPA


 


51
DAATPYGEPL PDHFLGAAQM VDELDLLPDA VAATLLADIG RYVPDWNLLV


 


101
SERCNSTVAE LVKGVDEVQK LTHFARVDSL ATPEERAQQA ETMRKMLLAM


 


151
VTDIRVVLIK LAMRTRTLQF LSNAPDSPEK RAVAKETLDI FAPLANRLGV


 


201
WQLKWQLEDL GFRHQEPEKY REIALLLDEK RTERLEYIEN FLDILRTELK


 


251
KYNIHFEVAG RPKHIYSIYK KMVKKKLSFD GLFDIRAVRI LVDTVPECYT


 


301
TLGIVHSLWQ PIPGEFDDYI ANPKGNGYKS LHTVIVGPEE KGVEVQIRTF


 


351
DMHQFNEFGV AAHWRYKEGG KGDSAYEQKI AWLRQLLDWR ENMAESGKED


 


401
LAAAFKTELF NDTIYVLTPH GKVLSLPTGA TPIDFAYALH SSIGDRCRGA


 


451
KVEGQIVPLS TPLENGQRVE IITAKEGHPS VNWLYEGWVK SGKAIGKIRA


 


501
YIRQQNADTV REEGRVQLDK QLAKLTPKPN LQELAENLGY KKPEDLYTAV


 


551
GQGEISNRAI QKACGTLNEP PPVPVSATTI VKQSKIKKGG KTGVLIDGED


 


601
GLMTTLAKCC KPAPPDDIAG FVTRERGISV HRKTCPSFRH LAEHAPEKVL


 


651
DASWAALQEG QVFAVDIEIR AQDRSGLLRD VSDALARHKL NVTAVQTQSR


 


701
DLEASMRFTL EVKQVNDLPR VLAGLGDVKG VLSVTRL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 419>:










m117-1.seq




1
ATGACCGCCA TCAGCCCGAT TCAAGACACG CAAAGCGCGA CTCTGCAAGA


 


51
ATTGCGCGAA TGGTTCGACA GCTACTGCGC CGCTCTGCCG GACAACGATA


 


101
AAAACCTCAT CGGTACCGCA TGGTTGCTGG CGCAGGAACA TTACCCCGCC


 


151
GATGCCGCCA CGCCGTATGG CGAGCCGCTG CCCGACCACT TCCTCGGCGC


 


201
GGCGCAAATG GTTCATGAAC TCGACCTGCT CCCCGATGCC GTCGCCGCCA


 


251
CCCTGCTTGC CGACATCGGA CGCTACGTCC CCGACTGGAA CCTATTGGTT


 


301
TCCGAACGCT GCAACAGTAC CGTCGCCGAG CTGGTCAAAG GTGTGGACGA


 


351
AGTGCAGAAA CTCACCCACT TCGCCCGGGT GGACAGCCTC GCCACGCCGG


 


401
AAGAACGCGC CCAGCAGGCA GAAACTATGC GGAAAATGCT GCTGGCGATG


 


451
GTTACCGACA TCCGCGTCGT GTTAATCAAA CTGGCGATGC GTACGCGCAC


 


501
CCTGCAATTT TTAAGCAACG CCCCCGACAG CCCCGAAAAA CGCGCCGTCG


 


551
CCAAAGAAAC CCTCGACATC TTCGCCCCGC TCGCCAACCG TTTGGGCGTG


 


601
TGGCAGCTCA AATGGCAGCT CGAAGATTTG GGCTTCCGCC ATCAAAAGCC


 


651
CGAAAAATAC CGCGAAATCG CGCTGCTTTT GGACGAAAAA CGCACCGAAC


 


701
GCCTCGAATA CATCGAAAAC TTCCTCAACA TCCTGCGCGG TGAACTCAAG


 


751
AAATACAATG TCCATTTCGA AGTCGCCGGC CGCCCGAAAC ACATCTACTC


 


801
CATTTACAAA AAAATGGTGA AGAAAAAACT CAGCTTCGAC GGCCTCTTTG


 


851
ACATCCGCGC CGTGCGAATT CTGGTTGATA CCGTCCCCGA GTGTTACACC


 


901
ACGCTGGGTA TCGTCCACAG CCTCTGGCAG CCCATTCCCG GCGAGTTCGA


 


951
CGACTACATC GCCAATCCCA AAGGCAACGG CTATAAAAGT TTGCACACCG


 


1001
TCATCGTCGG CCCGGAAGAC AAAGGCGTGG AAGTACAAAT CCGCACCTTC


 


1051
GATATGCACC AATTCAACGA ATTCGGTGTC GCCGCCCACT GGCGTTACAA


 


1101
AGAGGGCGGC AAGGGCGATT CCGCCTACGA ACAGAAAATC GCCTGGTTGC


 


1151
GCCAACTCTT GGACTGGCGC GAAAACATGG CGGAAAGCGG CAAGGAAGAC


 


1201
CTCGCCGCCG CCTTCAAAAC CGAGCTTTTC AACGACACGA TTTATGTTTT


 


1251
GACCCCGCAC GGCAAAGTCC TCTCCCTGCC CACGGGCGCG ACCCCCATCG


 


1301
ACTTCGCCTA CGCCCTGCAC AGCAGCATCG GCGACCGTTG CCGCGGTGCG


 


1351
AAAGTCGAAG GGCAGATTGT GCCGCTGTCC ACCCCGCTCG AAAACGGACA


 


1401
GCGCGTCGAA ATCATTACCG CCAAAGAAGG GCATCCTTCC GTCAACTGGC


 


1451
TTTACGAAGG CTGGGTCAAA TCCAACAAGG CAATCGGCAA AATCCGCGCC


 


1501
TACATCCGCC AGCAAAACGC CGACACCGTG CGCGAAGAAG GCCGCGTCCA


 


1551
ACTCGACAAA CAGCTTGCCA AACTCACGCC CAAACCCAAC CTGCAAGAGC


 


1601
TTGCCGAAAA TCTCGGCTAC AAAAAGCCAG AAGACCTCTA CACCGCCGTC


 


1651
GGACAAGGCG AAATTTCCAA CCGCGCCATC CAAAAAGCCT GCGGCACGCT


 


1701
GAACGAACCG CCGCCCGTAC CCGTCAGCGA AACCACCATC GTCAAACAGT


 


1751
CCAAAATCAA AAAAGGCGGC AAAAACGGCG TGCTCATCGA CGGCGAAGAC


 


1801
GGTCTGATGA CCACGCTTGC CAAATGCTGC AAACCCGCGC CGCCCGACGA


 


1851
TATTATCGGC TTCGTTACCC GCGAGCGCGG CATTTCAGTG CACCGCAAAA


 


1901
CCTGCCCGTC TTTCCAACAC CTCGCCGAAC ACGCGCCCGA AAAAGTGCTG


 


1951
GACGCAAGCT GGGCGGCATT GCAGGAAGGA CAAGTATTCG CCGTCGATAT


 


2001
CGAAATCCGC GCCCAAGACC GCTCCGGGCT TTTGCGCGAC GTATCCGACG


 


2051
CGCTCGCCCG CCACAAACTC AACGTTACCG CCGTGCAAAC CCAGTCCCGC


 


2101
GACTTGGAAG CCAGCATGAG GTTCACGCTC GAAGTCAAAC AAGTCAACGA


 


2151
CCTCCCGCGC GTCCTCGCCA GCCTCGGCGA CGTCAAAGGC GTATTGAGCG


 


2201
TTACCCGGCT TTAA






This corresponds to the amino acid sequence <SEQ ID 420; ORF 117-1>:










m117-1.pep




1
MTAISPIQDT QSATLQELRE WFDSYCAALP DNDKNLIGTA WLLAQEHYPA


 


51
DAATPYGEPL PDHFLGAAQM VHELDLLPDA VAATLLADIG RYVPDWNLLV


 


101
SERCNSTVAE LVKGVDEVQK LTHFARVDSL ATPEERAQQA ETMRKMLLAM


 


151
VTDIRVVLIK LAMRTRTLQF LSNAPDSPEK RAVAKETLDI FAPLANRLGV


 


201
WQLKWQLEDL GFRHQKPEKY REIALLLDEK RTERLEYIEN FLNILRGELK


 


251
KYNVHFEVAG RPKHIYSIYK KMVKKKLSFD GLFDIRAVRI LVDTVPECYT


 


301
TLGIVHSLWQ PIPGEFDDYI ANPKGNGYKS LHTVIVGPED KGVEVQIRTF


 


351
DMHQFNEFGV AAHWRYKEGG KGDSAYEQKI AWLRQLLDWR ENMAESGKED


 


401
LAAAFKTELF NDTIYVLTPH GKVLSLPTGA TPIDFAYALH SSIGDRCRGA


 


451
KVEGQIVPLS TPLENGQRVE IITAKEGHPS VNWLYEGWVK SNKAIGKIRA


 


501
YIRQQNADTV REEGRVQLDK QLAKLTPKPN LQELAENLGY KKPEDLYTAV


 


551
GQGEISNRAI QKACGTLNEP PPVPVSETTI VKQSKIKKGG KNGVLIDGED


 


601
GLMTTLAKCC KPAPPDDIIG FVTRERGISV HRKTCPSFQH LAEHAPEKVL


 


651
DASWAALQEG QVFAVDIEIR AQDRSGLLRD VSDALARHKL NVTAVQTQSR


 


701
DLEASMRFTL EVKQVNDLPR VLASLGDVKG VLSVTRL*






m117-1/g117-1 98.2% identity in 737 aa overlap





m117-1/RelA









sp|P55133|RELA_VIBSS GTP PYROPHOSPHOKINASE (ATP:GTP 3′-PYROPHOSPHOTRANSFERASE)



(PPGPP SYNTHETASE I) >gi|537617 (U13769) ppGpp synthetase I


[Vibrio sp.] Length = 744 Score = 536 bits (1366), Expect = e−151


Identities = 288/685 (42%), Positives = 432/685 (63%), Gaps = 31/685 (4%)










Query:
74
LDLLPDAVAATLLADI---GRYVPDWNLLVSERCNSTVAELVKGVDEVQKLTHFARVDSL
130




L +  D + A LL  +   G Y  D    + E  + T+  LV+GV+++  ++   ++ S


Sbjct:
68
LSMDADTLIAALLYPLVEGGCYSTD---ALKEEYSGTILHLVQGVEQMCAIS---QLKST
121


 


Query:
131
ATPEERAQQAETMRKMLLAMVTDIRVVLIKLAMRTRTLQFLSNAPDSPEKRAVAKETLDI
190




A    +A Q + +R+MLL+MV D R V+IKLA R   L+ + + PD   +RA A+E  +I


Sbjct:
122
AEETAQAAQVDNIRRMLLSMVDDFRCVVIKLAERICNLREVKDQPDEV-RRAAAQECANI
180


 


Query:
191
FAPLANRLGVWQLKWQLEDLGFRHQKPEKYREIALLLDEKRTERLEYIENFLNILRGELK
250




+APLANRLG+ QLKW++ED  FR+Q P+ Y++IA  L E+R +R +YI +F++ L   +K


Sbjct:
181
YAPLANRLGIGQLKWEIEDYAFRYQHPDTYKQIAKQLSERRIDREDYITHFVDDLSDAMK
240


 


Query:
251
KYNVHFEVAGRPKHIYSIYKKMVKKKLSFDGLFDIRAVRILVDTVPECYTTLGIVHSLWQ
310




  N+  EV GRPKHIYSI++KM KK L FD LFD+RAVRI+ + + +CY  LG+VH+ ++


Sbjct:
241
ASNIRAEVQGRPKHIYSIWRKMQKKSLEFDELFDVRAVRIVAEELQDCYAALGVVHTKYR
300


 


Query:
311
PIPGEFDDYIANPKGNGYKSLHTVIVGPEDKGVEVQIRTFDMHQFNEFGVAAHWRYKEG-
369




 +P EFDDY+ANPK NGY+S+HTV++GPE K +E+QIRT  MH+ +E GVAAHW+YKEG


Sbjct:
301
HLPKEFDDYVANPKPNGYQSIHTVVLGPEGKTIEIQIRTKQMHEESELGVAAHWKYKEGT
360


 


Query:
370
--GKGDSAYEQKIAWLRQLLDWRENMAESGKEDLAAAFKTELFNDTIYVLTPHGKVLSLP
427




  G   SAY++KI WLR+LL W+E M++SG  ++    ++++F+D +Y  TP G V+ LP


Sbjct:
361
ASGGAQSAYDEKINWLRKLLAWQEEMSDSG--EMLDELRSQVFDDRVYAFTPKGDVVDLP
418


 


Query:
428
TGATPIDFAYALHSSIGDRCRGAKVEGQIVPLSTPLENGQRVEIITAKEGHPSVNWLYE-
486




+ ATP+DFAY +HS +G RC GAKVEG+IVP +  L+ G +VEIIT KE +PS +WL


Sbjct:
419
SNATPLDFAYHIHSEVGHRCIGAKVEGRIVPFTYHLQMGDQVEIITQKEPNPSRDWLNPN
478


 


Query:
487
-GWVKSNKAIGKIRAYIRQQNADTVREEGRVQLDKQLAKL--TPKPNLQELAENLGYKKP
543




 G+V S++A  K+ A+ R+Q+ D     G+  L+ +L K+  T K      A+    K P


Sbjct:
479
LGFVTSSRARAKVHAWFRKQDRDKNIIAGKEILEAELVKIHATLKDAQYYAAKRFNVKSP
538


 


Query:
544
EDLYTAVGQGEIS-NRAIQKACGTLNEPPPVPVSETTIVKQSKI--------KKGGKNGV
594




E+LY  +G G++  N+ I      +N+P      +  + K S+         KK  ++ V


Sbjct:
539
EELYAGIGSGDLRINQVINHINALVNKPTAEEEDQQLLEKLSEASNKQATSHKKPQRDAV
598


 


Query:
595
LIDGEDGLMTTLAKCCKPAPPDDIIGFVTRERGISVHRKTCPSFQHLAEHAPEKVLDASW
654




+++G D LMT LA+CC+P P DDI GFVT+ RGISVHR  C   + L  HAPE+++D  W


Sbjct:
599
VVEGVDNLMTHLARCCQP IPGDDIQGFVTQGRGISVHRMDCEQLEELRHHAPERIIDTVW
658


 


Query:
655
AALQEGQVFAVDIEIRAQDRSGLLRDVSDALARHKLNVTAVQTQ--SRDLEASMRFTLEV
712




     G  + + + + A +R+GLL+++++ L   K+ V  ++++   +   + M F LE+


Sbjct:
659
GGGFVGN-YT I TVRVTASERNGLLKELTNTLMNEKVKVAGMKSRVDYKKQMSIMDFELEL
717


 


Query:
713
KQVNDLPRVLASLGDVKGVLSVTRL
737




  +  L RVL  +  VK V    RL


Sbjct:
718
TDLEVLGRVLKRIEQVKDVAEAKRL
742






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 421>:










a117-1.seq




1
ATGACCGCCA TCAGCCCGAT TCAAGACACG CAAAGCGCGA CTCTGCAAGA


 


51
ATTGCGCGAA TGGTTCGACA GCTACTGCAC CGCGCTGCCG AACAACGATA


 


101
AAAAACTTGT CTTAGCCGCC CGTTCGCTGG CGGAAGCACA TTACCCCGCC


 


151
GATGCCGCCA CGCCGTATGG CGAACCGCTG CCCGACCACT TCCTCGGCGC


 


201
GGCGCAAATG GTTCATGAAC TCGACCTGCT CCCCGATGCC GTCGCCGCCA


 


251
CCCTGCTTGC CGACATCGGA CGCTACGTCC CCGACTGGAA CCTATTGGTT


 


301
TCCGAACGCT GCAACAGTAC CGTCGCCGAG CTGGTCAAAG GTGTGGACGA


 


351
AGTGCAGAAA CTCACCCACT TCGCCCGGGT GGACAGCCTC GCCACGCCGG


 


401
AAGAACGCGC CCAGCAGGCA GAAACTATGC GGAAAATGCT GCTGGCGATG


 


451
GTTACCGACA TCCGCGTCGT GTTAATCAAA CTGGCGATGC GTACGCGCAC


 


501
CCTGCAATTT TTAAGCAACG CCCCCGACAG CCCCGAAAAA CGCGCCGTCG


 


551
CCAAAGAAAC CCTCGACATC TTCGCCCCGC TCGCCAACCG TTTGGGCGTG


 


601
TGGCAGCTCA AATGGCAGCT CGAAGATTTG GGCTTCCGCC ATCAAGAACC


 


651
CGAAAAATAC CGCGAAATCG CCCTGCTTTT GGACGAAAAA CGCACCGAAC


 


701
GCCTCGAATA CATCGAAAAC TTCCTTAATA TCCTGCGTAC GGAACTCAAA


 


751
AAATACAATA TCCACTTTGA AGTCGCCGGC CGTCCGAAAC ACATCTACTC


 


801
CATTTACAAA AAAATGGTGA AGAAAAAACT CAGCTTCGAC GGGTTGTTCG


 


851
ACATCCGCGC CGTGCGGATT CTGGTTGATA CCGTCCCCGA GTGTTACACC


 


901
ACACTGGGCA TTGTCCACAG CCTCTGGCAG CCCATTCCCG GCGAGTTCGA


 


951
CGACTACATC GCCAACCCGA AAGGCAACGG CTATAAAAGT TTGCACACCG


 


1001
TCATCGTCGG CCCGGAAGAC AAAGGCGTGG AAGTGCAAAT CCGCACCTTC


 


1051
GATATGCACC AATTCAACGA ATTCGGTGTC GCCGCGCACT GGCGTTACAA


 


1101
AGAGGGCGGC AAAGGCGATT CCGCCTACGA ACAAAAAATC GCCTGGTTAC


 


1151
GCCAACTTTT GGACTGGCGC GAAAACATGG CGGAAAGCGG CAAGGAAGAC


 


1201
CTCGCCGCCG CCTTCAAAAC CGAGCTTTTC AACGACACGA TTTATGTTTT


 


1251
GACCCCGCAC GGCAAAGTCC TCTCCCTGCC CACAGGCGCG ACCCCCATCG


 


1301
ACTTCGCCTA CGCCCTGCAC AGCAGCATCG GCGACCGTTG CCGCGGTGCG


 


1351
AAAGTCGAAG GGCAGATTGT GCCGCTGTCC ACCCCGCTCG AAAACGGACA


 


1401
GCGTGTCGAA ATCATTACCG CCAAAGAAGG GCATCCTTCC GTCAACTGGC


 


1451
TTTACGAAGG CTGGGTCAAA TCCAACAAGG CAATCGGCAA AATCCGCGCC


 


1501
TACATCCGCC AGCAAAACGC CGACACCGTG CGCGAAGAAG GCCGCGTCCA


 


1551
ACTCGACAAA CAGCTTGCCA AACTCACGCC CAAACCCAAC CTGCAAGAGC


 


1601
TTGCCGAAAA TCTCGGCTAC AAAAAGCCAG AAGACCTCTA CACCGCCGTC


 


1651
GGACAAGGCG AAATTTCCAA CCGCGCCATC CAAAAAGCCT GCGGCACGCT


 


1701
GAACGAACCG CCGCCCGTAC CCGTCAGCGA AACCACCATC GTCAAACAGT


 


1751
CCAAAATCAA AAAAGGCGGC AAAAACGGCG TGCTCATCGA CGGCGAAGAC


 


1801
GGTCTGATGA CCACGCTTGC CAAATGCTGC AAACCCGCGC CGCCCGACGA


 


1851
CATTGTCGGC TTCGTTACCC GCGATCGCGG CATTTCGGTA CACCGCAAAA


 


1901
CCTGCCCCTC TTTCCGACAC CTCGCCGAAC ACGCGCCCGA AAAAGTACTG


 


1951
GACGCAAGTT GGGCGGCGTT GCAGGAAGGA CAAGTGTTCG CCGTCGATAT


 


2001
CGAAATCCGC GCCCAAGACC GCTCCGGGCT TTTGCGCGAC GTATCCGACG


 


2051
CGCTCGCCCG CCACAAACTC AACGTTACCG CCGTGCAAAC CCAGTCCCGC


 


2101
GACTTGGAAG CCAGCATGAG GTTCACGCTC GAAGTCAAAC AAGTTACCGA


 


2151
CCTCCCACGC GTCCTCGCCA GCCTCGGCGA CGTCAAAGGC GTATTGAGCG


 


2201
TTACCCGGCT TTAA






This corresponds to the amino acid sequence <SEQ ID 422; ORF 117-1.a>:










a117-1.pep




1
MTAISPIQDT QSATLQELRE WFDSYCTALP NNDKKLVLAA RSLAEAHYPA


 


51
DAATPYGEPL PDHFLGAAQM VHELDLLPDA VAATLLADIG RYVPDWNLLV


 


101
SERCNSTVAE LVKGVDEVQK LTHFARVDSL ATPEERAQQA ETMRKMLLAM


 


151
VTDIRVVLIK LAMRTRTLQF LSNAPDSPEK RAVAKETLDI FAPLANRLGV


 


201
WQLKWQLEDL GFRHQEPEKY REIALLLDEK RTERLEYIEN FLNILRTELK


 


251
KYNIHFEVAG RPKHIYSIYK KMVKKKLSFD GLFDIRAVRI LVDTVPECYT


 


301
TLGIVHSLWQ PIPGEFDDYI ANPKGNGYKS LHTVIVGPED KGVEVQIRTF


 


351
DMHQFNEFGV AAHWRYKEGG KGDSAYEQKI AWLRQLLDWR ENMAESGKED


 


401
LAAAFKTELF NDTIYVLTPH GKVLSLPTGA TPIDFAYALH SSIGDRCRGA


 


451
KVEGQIVPLS TPLENGQRVE IITAKEGHPS VNWLYEGWVK SNKAIGKIRA


 


501
YIRQQNADTV REEGRVQLDK QLAKLTPKPN LQELAENLGY KKPEDLYTAV


 


551
GQGEISNRAI QKACGTLNEP PPVPVSETTI VKQSKIKKGG KNGVLIDGED


 


601
GLMTTLAKCC KPAPPDDIVG FVTRDRGISV HRKTCPSFRH LAEHAPEKVL


 


651
DASWAALQEG QVFAVDIEIR AQDRSGLLRD VSDALARHKL NVTAVQTQSR


 


701
DLEASMRFTL EVKQVTDLPR VLASLGDVKG VLSVTRL*






a117-1/m117-1 97.7% identity in 737 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 423>:










g118.seq




1
ATGTGCGAGT TCAAGGATTT TAGAAGAAAC ATCCCTTGTT TTGAAGAGTA


 


51
TGACGAAAAT TCATTTATTG GCAAATGGTA TGATGACGGG GTGTGGGATG


 


101
ATGAAGAATA TTGGAAGCTG GAGAATGATT TAATcgaGGT TAGGAGAAAA


 


151
TATCCTTATC CGATGGATAT ACCAAGGGAT ATTGTGATTG GAATCGGTAC


 


201
CATTATTGAT TTTTTAATGG TTCCAAATTG GGAGCTTTTT GAAATTAAAG


 


251
CTTCCCCTTG GTTGCCTGAT AGCGTGGGAA TTCATGAACG TTATGAAAGA


 


301
TTCACAACGA TGCTCCGTTA TATTTTTACC GAGAAAGACA TAGTCAACGT


 


351
GCGATTTGAT TATTACAaCA AAAAATAG






This corresponds to the amino acid sequence <SEQ ID 424; ORF 118.ng>:










g118.pep




1
MCEFKDFRRN IPCFEEYDEN SFIGKWYDDG VWDDEEYWKL ENDLIEVRRK


 


51
YPYPMDIPRD IVIGIGTIID FLMVPNWELF EIKASPWLPD SVGIHERYER


 


101
FTTMLRYIFT EKDIVNVRFD YYNKK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 425>:










m118.seq




1
ATGTGTGAGT TCAAGGATAT TATAAGAAAC GTTCCTTATT TTGAGGGGTA


 


51
TGACGAAAAT TCATTTATTG GCAAATGGTA TGATGACGGG GTGTGGGATG


 


101
ATGAAGAATA TTGGAAGTTG GAGAATGATT TAATCGAGGT TAGAAAAAAA


 


151
TATCCTTATC CGATGGACAT ACCAAGATAT GTTGTCATTG GAATCGGTAC


 


201
CATTATTGAT TTCTTAATGG TTCCAAATTG GAAACTTTTT GAAATTAAAG


 


251
CTTCCCCTTG GTTGCCTGAT AGTGTGGGAA TTCATGAACG TTATGAAAGA


 


301
TTCACAACGA TGCTCCGTTA TATTTTTACC GAGAAAGACA TAGTCAACGT


 


351
GCGATTTGAT TATTACAACA AAAAATAG






This corresponds to the amino acid sequence <SEQ ID 426; ORF 118>:










m118.pep




1
MCEFKDIIRN VPYFEGYDEN SFIGKWYDDG VWDDEEYWKL ENDLIEVRKK


 


51
YPYPMDIPRY VVIGIGTIID FLMVPNWKLF EIKASPWLPD SVGIHERYER


 


101
FTTMLRYIFT EKDIVNVRFD YYNKK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 118 shows 92.8% identity over a 125 aa overlap with a predicted ORF (ORF 118.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 427>:










a118.seq




1
ATGTGTGAGT TCAAGGATTT TAGAAGAAAC ATCCCTTGTT TTGAAGAGTA


 


51
TGACGAAAAT TCATTTATTG GCAAATGGTA TGATGACGGG GTGTGGGATG


 


101
ATGAAGAATA TTGGAAATTG GAGAATGATT TAATCGAGGT TAGAAAAAAA


 


151
TATCCTTATC CGATGGATAT ACCAAGGGAT ATTGTGATTG GAATCGGTAC


 


201
CATTATTGAT TTTTTAATGG TTCCAAATTG GGAGCTTTTT GAAATTAAAG


 


251
CTTCCCCTTG GTTGCCTGAT AGTGTGGGAA TTCATGAACG TTATGAAAGA


 


301
TTCACAACGA TGCTCCGTTA TATTTTTACC GAGAAAGACA TAGTCAACGT


 


351
GCGATTTGAT TATTACAACA AAAAATAG






This corresponds to the amino acid sequence <SEQ ID 428; ORF 118.a>:










a118.pep




1
MCEFKDFRRN IPCFEEYDEN SFIGKWYDDG VWDDEEYWKL ENDLIEVRKK


 


51
YPYPMDIPRD IVIGIGTIID FLMVPNWELF EIKASPWLPD SVGIHERYER


 


101
FTTMLRYIFT EKDIVNVRFD YYNKK*






m118/a118 93.6% identity in 125 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 429>:










g120.seq




1
ATGATGAAGA CTTTTAAAAA TATATTTTCC GCCGCCATTT TGTCCGCCGC


 


51
CCTGCCGTGC GCGTATGCGG CAAGGCTACC CCAATCCGCC GTGCTGCACT


 


101
ATTCCGGCAG CTACGGCATT CCCGCCACGA TGACATTTGA ACGCAGCGGC


 


151
AATGCTTACA AAATCGTTTC GACGATTAAA GTGCCGCTAT ACAATATCCG


 


201
TTTCGAATCC GGCGGTACGG TTGTCGGCAA TACCCTGCAC CCTGCCTACT


 


251
ATAAAGACAT ACGCAGGGGC AAACTGTATG CGGAAGCCAA ATTCGCCGAC


 


301
GGCAGCGTAA CCTACGGCAA AGCGGGCGAG AGCAAAACCG AGCAAAGCCC


 


351
CAAGGCTATG GATTTGTTCA CGCTTGCCTG GCAGTTGGCG GCAAATGACG


 


401
CGAAACTCCC CCCGGGTCTG AAAATCACCA ACGGCAAAAA ACTTTATTCC


 


451
GTCGGCGGCC TGAATAAGGC GGGTACGGGA AAATACAGCA Taggcggcgt


 


501
gGAAACCGAA GTCGTCAAAT ATCGGGTGCG GCGCGGCGAC GATACGGTAA


 


551
CGTATTTCTT CGCACCGTCC CTGAACAATA TTCCGGCACA AATCGGCTAT


 


601
ACCGAcgaCG GCAAAACCTA TACGCTGAAG CTCAAATCGG TGCAGATCAA


 


651
CGGACAGGCC GCCAAACCGT AA






This corresponds to the amino acid sequence <SEQ ID 430; ORF 120.ng>:










g120.pep




1
MMKTFKNIFS AAILSAALPC AYAARLPQSA VLHYSGSYGI PATMTFERSG


 


51
NAYKIVSTIK VPLYNIRFES GGTVVGNTLH PAYYKDIRRG KLYAEAKFAD


 


101
GSVTYGKAGE SKTEQSPKAM DLFTLAWQLA ANDAKLPPGL KITNGKKLYS


 


151
VGGLNKAGTG KYSIGGVETE VVKYRVRRGD DTVTYFFAPS LNNIPAQIGY


 


201
TDDGKTYTLK LKSVQINGQA AKP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 431>:










m120.seq




1
ATGATGAAGA CTTTTAAAAA TATATTTTCC GCCGCCATTT TGTCCGCCGC


 


51
CCTGCCGTGC GCGTATGCGG CAGGGCTGCC CCAATCCGCC GTGCTGmACT


 


101
ATTCCGGCAG CTACGGCATT CCCGCCACGA TGACATTTGA ACGCAGCGGC


 


151
AATGCTTACA AAATCGTTTC GACGATTAAA GTGCCGCTAT ACAATATCCG


 


201
TTTCGAGTCC GGCGGTACGG TTGTCGGCAA TACCCTGCAC CCTACCTACT


 


251
ATAGAGACAT ACGCAGGGGC AAACTGTATG CGGAAGCcAA ATTCGCCGAC


 


301
GGCAGCGTAA CTTACGGCAA AGCGGGCGAG AGCAAAACCG AGCAAAGCCC


 


351
CAAGGCTATG GATTTGTTCA CGCTTGCCTG GCAGTTGGCG GCAAATGACG


 


401
CGAAACTCCC CCCGGGGCTG AAAATCACCA ACGGCAAAAA ACTTTATTCC


 


451
GTCGGCGGTT TGAATAAGGC GGGTACAGGA AAATACAGCA TAGGCGGCGT


 


501
GGAAACCGAA GTCGTCAAAT ATCGGGTGCG GCGCGGCGAC GATGCGGTAA


 


551
TGTATTTCTT CGCACCGTCC CTGAACAATA TTCCGGCACA AATCGGCTAT


 


601
ACCGACGACG GCAAAACCTA TACGCTGAAA CTCAAATCGG TGCAGATCAA


 


651
CGGCCAGGCA GCCAAACCG






This corresponds to the amino acid sequence <SEQ ID 432; ORF 120>:










m120.pep




1
MMKTFKNIFS AAILSAALPC AYAAGLPQSA VLXYSGSYGI PATMTFERSG


 


51
NAYKIVSTIK VPLYNIRFES GGTVVGNTLH PTYYRDIRRG KLYAEAKFAD


 


101
GSVTYGKAGE SKTEQSPKAM DLFTLAWQLA ANDAKLPPGL KITNGKKLYS


 


151
VGGLNKAGTG KYSIGGVETE VVKYRVRRGD DAVMYFFAPS LNNIPAQIGY


 


201
TDDGKTYTLK LKSVQINGQA AKP






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 120 shows 97.3% identity over a 223 aa overlap with a predicted ORF (ORF 120.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 433>:










a120.seq




1
ATGATGAAGA CTTTTAAAAA TATATTTTCC GCCGCCATTT TGTCCGCCGC


 


51
CCTGCCGTGC GCGTATGCGG CAGGGCTGCC CCAATCCGCC GTGCTGCACT


 


101
ATTCCGGCAG CTACGGCATT CCCGCCACGA TGACATTTGA ACGCAGCGGC


 


151
AATGCTTACA AAATCGTTTC GACGATTAAA GTGCCGCTAT ACAATATCCG


 


201
TTTCGAGTCC GGCGGTACGG TTGTCGGCAA TACCCTGCAC CCTACCTACT


 


251
ATAGAGACAT ACGCAGGGGC AAACTGTATG CGGAAGCCAA ATTCGCCGAC


 


301
GGCAGCGTAA CCTACGGCAA AGCGGGCGAG AGCAAAACCG AGCAAAGCCC


 


351
CAAGGCTATG GATTTGTTCA CGCTTGCCTG GCAGTTGGCG GCAAATGACG


 


401
CGAAACTCCC CCCGGGGCTG AAAATCACCA ACGGCAAAAA ACTTTATTCC


 


451
GTCGGCGGTT TGAATAAGGC GGGTACAGGA AAATACAGCA TAGGCGGCGT


 


501
GGAAACCGAA GTCGTCAAAT ATCGGGTGCG GCGCGGCGAC GATGCGGTAA


 


551
TGTATTTCTT CGCACCGTCC CTGAACAATA TTCCGGCACA AATCGGCTAT


 


601
ACCGACGACG GCAAAACCTA TACGCTGAAA CTCAAATCGG TGCAGATCAA


 


651
CGGCCAGGCA GCCAAACCGT AA






This corresponds to the amino acid sequence <SEQ ID 434; ORF 120.a>:










a120.pep




1
MMKTFKNIFS AAILSAALPC AYAAGLPQSA VLHYSGSYGI PATMTFERSG


 


51
NAYKIVSTIK VPLYNIRFES GGTVVGNTLH PTYYRDIRRG KLYAEAKFAD


 


101
GSVTYGKAGE SKTEQSPKAM DLFTLAWQLA ANDAKLPPGL KITNGKKLYS


 


151
VGGLNKAGTG KYSIGGVETE VVKYRVRRGD DAVMYFFAPS LNNIPAQIGY


 


201
TDDGKTYTLK LKSVQINGQA AKP*






m120/a120 99.6% identity in 223 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 435>:










g121.seq




1
ATGGAAACAC AGCTTTACAT CGGCATTATG TCGGGAACCA GTATGGACGG


 


51
GGCGGATGCC GTGCTGGTAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCTGACC GGTTGCGCCG CAAATTGCTG


 


151
GATTTGCAGG ACACAGGCAC AGACGAACTG CACCGCAGCA GGATGTTGTC


 


201
GCAAGAACTC AGCCGCCTGT ACGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCTCCGTGC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCCGAC ACGCGCCGGA ACACGGTtac AGCATACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACTGa cgcggatttT TACCGTCggc gacttcCGCA


 


401
GCCGCGACCT TGCTGCCGGC GGacaAGGTG CGCCGCTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA TGACAGGGAA ACACGCGTGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGGCGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGGCCGGGC AATATGCTGA TGGAcgcgtg gacgcaggca


 


601
cacTGGcagc TGCCTTACGA CAAAAacggt gcAAAGgcgg cacAAGGCAA


 


651
catatTGCcg cAACTGCTCG gcaggctGCT CGCCcaccCG TATTTCTCAC


 


701
AACCCcaccc aaAAAGCACG GGgcGCGaac TgtttgcccT AAattggctc


 


751
gaaacctAcc ttgacggcgg cgaaaaccga tacgacgtat tgcggacgct


 


801
ttcccgattc accgcgcaaA ccgTttggga cgccgtctca CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAA CTGAACCTCG ATCCTCAATG GGTGGAGGCG gccgCATTtg


 


1001
cgtggttggC GGCGTGTTGG ATTAACCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCGACCGGCG CATCCAAACC GTGTATTCTG GGCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 436; ORF 121.ng>:










g121.pep




1
METQLYIGIM SGTSMDGADA VLVRMDGGKW LGAEGHAFTP YPDRLRRKLL


 


51
DLQDTGTDEL HRSRMLSQEL SRLYAQTAAE LLCSQNLAPC DITALGCHGQ


 


101
TVRHAPEHGY SIQLADLPLL AELTRIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDDRE TRVVLNIGGI ANISVLPPGA PAFGFDTGPG NMLMDAWTQA


 


201
HWQLPYDKNG AKAAQGNILP QLLGRLLAHP YFSQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVWDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAE LNLDPQWVEA AAFAWLAACW INRIPGSPHK


 


351
ATGASKPCIL GAGYYY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 437>:










m121.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CCAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC AGACGAACTG CACCGCAGCA GGATTTTGTC


 


201
GCAAGAACTC AGCCGCCTAT ATGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCACCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCCGAC ACGCGCCGGA ACACGGTTAC AGCATACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


401
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


451
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


501
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


551
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


601
xxxxxxCAGC TTCCTTACGA CAAAAACGGT GCAAAGTCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACGCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCAT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGTTTT ACCGCGCAAA CCGTTTGCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGACG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAC CTGAACCTCG ATCCGCAATG GGTGGAAGCC GCCGnATTTG


 


1001
CGTGGTTGGC GGCGTGTTGG ATTAATCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG AnCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 438; ORF 121>:










m121.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRQLL


 


51
DLQDTGADEL HRSRILSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHGY SIQLADLPLL Axxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


151
xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx xxxxxxxxxx


 


201
xxQLPYDKNG AKSAQGNILP QLLDRLLAHP YFAQRHPKST GRELFAINWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVCDAVS HAAADARQMY ICDGGIRNPV


 


301
LMADLAECFG TRVSLHSTAD LNLDPQWVEA AXFAWLAACW INRIPGSPHK


 


351
ATGASKPCIL XAGYYY*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 121 shows 73.5% identity over a 366 aa overlap with a predicted ORF (ORF121.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 439>:










a121.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CAAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC GGACGAACTG CACCGCAGCA GGATGTTGTC


 


201
GCAAGAACTC AGCCGCCTGT ACGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCGCCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCAGAC ACGCGCCGGA ACACAGTTAC AGCGTACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACGGA CTCAGATTTT TACCGTCGGC GACTTCCGCA


 


401
GCCGCGACCT TGCGGCCGGC GGACAAGGCG CGCCGCTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA CGACAGGGAA ACACGCGCGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGACGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGACCGGGC AATATGCTGA TGGACGCGTG GATGCAGGCA


 


601
CACTGGCAGC TTCCTTACGA CAAAAACGGT GCAAAGGCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACCCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCCT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGATTC ACCGCGCAAA CCGTTTTCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAA CTGAACCTCG ATCCGCAATG GGTAGAAGCC GCCGCGTTCG


 


1001
CATGGATGGC GGCGTGTTGG GTCAACCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG GGCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 440; ORF 121.a>:










a121.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRKLL


 


51
DLQDTGADEL HRSRMLSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHSY SVQLADLPLL AERTQIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDDRE TRAVLNIGGI ANISVLPPDA PAFGFDTGPG NMLMDAWMQA


 


201
HWQLPYDKNG AKAAQGNILP QLLDRLLAHP YFAQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVFDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAE LNLDPQWVEA AAFAWMAACW VNRIPGSPHK


 


351
ATGASKPCIL GAGYYY*






m121/a121 74.0% identity in 366 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 441>:










m121-1.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CCAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC AGACGAACTG CACCGCAGCA GGATTTTGTC


 


201
GCAAGAACTC AGCCGCCTAT ATGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCACCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCCGAC ACGCGCCGGA ACACGGTTAC AGCATACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACGGA CGCGGATTTT TACCGTCGGC GACTTCCGCA


 


401
GCCGCGACCT TGCGGCCGGC GGACAAGGCG CGCCACTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA CAACAGGGAA ACACGCGCGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGACGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGGCCGGGC AATATGCTGA TGGACGCGTG GACGCAGGCA


 


601
CACTGGCAGC TTCCTTACGA CAAAAACGGT GCAAAGGCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACCCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCCT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGTTTT ACCGCGCAAA CCGTTTGCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAC CTGAACCTCG ATCCGCAATG GGTGGAAGCC GCCGNATTTG


 


1001
CGTGGTTGGC GGCGTGTTGG ATTAATCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG ANCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 442; ORF 121-1>:










m121-1.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRQLL


 


51
DLQDTGADEL HRSRILSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHGY SIQLADLPLL AERTRIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDNRE TRAVLNIGGI ANISVLPPDA PAFGFDTGPG NMLMDAWTQA


 


201
HWQLPYDKNG AKAAQGNILP QLLDRLLAHP YFAQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVCDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAD LNLDPQWVEA AXFAWLAACW INRIPGSPHK


 


351
ATGASKPCIL XAGYYY*






m121-1/g121 95.6% identity in 366 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 443>:










a121-1.seq




1
ATGGAAACAC AGCTTTACAT CGGCATCATG TCGGGAACCA GCATGGACGG


 


51
GGCGGATGCC GTACTGATAC GGATGGACGG CGGCAAATGG CTGGGCGCGG


 


101
AAGGGCACGC CTTTACCCCC TACCCCGGCA GGTTACGCCG CAAATTGCTG


 


151
GATTTGCAGG ACACAGGCGC GGACGAACTG CACCGCAGCA GGATGTTGTC


 


201
GCAAGAACTC AGCCGCCTGT ACGCGCAAAC CGCCGCCGAA CTGCTGTGCA


 


251
GTCAAAACCT CGCGCCGTCC GACATTACCG CCCTCGGCTG CCACGGGCAA


 


301
ACCGTCAGAC ACGCGCCGGA ACACAGTTAC AGCGTACAGC TTGCCGATTT


 


351
GCCGCTGCTG GCGGAACGGA CTCAGATTTT TACCGTCGGC GACTTCCGCA


 


401
GCCGCGACCT TGCGGCCGGC GGACAAGGCG CGCCGCTCGT CCCCGCCTTT


 


451
CACGAAGCCC TGTTCCGCGA CGACAGGGAA ACACGCGCGG TACTGAACAT


 


501
CGGCGGGATT GCCAACATCA GCGTACTCCC CCCCGACGCA CCCGCCTTCG


 


551
GCTTCGACAC AGGACCGGGC AATATGCTGA TGGACGCGTG GATGCAGGCA


 


601
CACTGGCAGC TTCCTTACGA CAAAAACGGT GCAAAGGCGG CACAAGGCAA


 


651
CATATTGCCG CAACTGCTCG ACAGGCTGCT CGCCCACCCG TATTTCGCAC


 


701
AACCCCACCC TAAAAGCACG GGGCGCGAAC TGTTTGCCCT AAATTGGCTC


 


751
GAAACCTACC TTGACGGCGG CGAAAACCGA TACGACGTAT TGCGGACGCT


 


801
TTCCCGATTC ACCGCGCAAA CCGTTTTCGA CGCCGTCTCA CACGCAGCGG


 


851
CAGATGCCCG TCAAATGTAC ATTTGCGGCG GCGGCATCCG CAATCCTGTT


 


901
TTAATGGCGG ATTTGGCAGA ATGTTTCGGC ACACGCGTTT CCCTGCACAG


 


951
CACCGCCGAA CTGAACCTCG ATCCGCAATG GGTAGAAGCC GCCGCGTTCG


 


1001
CATGGATGGC GGCGTGTTGG GTCAACCGCA TTCCCGGTAG TCCGCACAAA


 


1051
GCAACCGGCG CATCCAAACC GTGTATTCTG GGCGCGGGAT ATTATTATTG


 


1101
A






This corresponds to the amino acid sequence <SEQ ID 444; ORF 121-1.a>:










a121-1.pep




1
METQLYIGIM SGTSMDGADA VLIRMDGGKW LGAEGHAFTP YPGRLRRKLL


 


51
DLQDTGADEL HRSRMLSQEL SRLYAQTAAE LLCSQNLAPS DITALGCHGQ


 


101
TVRHAPEHSY SVQLADLPLL AERTQIFTVG DFRSRDLAAG GQGAPLVPAF


 


151
HEALFRDDRE TRAVLNIGGI ANISVLPPDA PAFGFDTGPG NMLMDAWMQA


 


201
HWQLPYDKNG AKAAQGNILP QLLDRLLAHP YFAQPHPKST GRELFALNWL


 


251
ETYLDGGENR YDVLRTLSRF TAQTVFDAVS HAAADARQMY ICGGGIRNPV


 


301
LMADLAECFG TRVSLHSTAE LNLDPQWVEA AAFAWMAACW VNRIPGSPHK


 


351
ATGASKPCIL GAGYYY*






m121-1/a121-1 96.4% identity in 366 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 445>:










g122.seq




1
ATGGCTTTAC TGAGCATCCG CAAGCTGCAC AAACAATACG GCAGCGTAAC


 


51
CGCCATCCAA TCCTTAGACT TGGACTTGGA AAAAGGCGAA GtcatCGTAC


 


101
TGCTGGGCCC gTccggctgc ggCAAATCCA CCCTcctgcg ctgcgtcaaC


 


151
GGTTTGGAGC CGCACCAagg cgGCAGCATC GTGATGGACG GTgtcgGCGA


 


201
ATTCggcAAA GACGTTTCCT GGCAAACCGC CCGGCAAAAa gtcggtatgg


 


251
tctttcaaag taacgAactg Tttgcccaca tgaccgtcat cgAaaacatc


 


301
ttcttAggcC CGGTAAagga aCAAAAcCgc gaccgtgccg aagcaGAGGC


 


351
gCAAGCCGGC AAactGttgg aacgcgTCGG actgctAGAC CGCAAAAACG


 


401
CCTATCCGCG CGAACTTTCC GGCGGTCAGA AACAGCGCAT CGCCATTGTC


 


451
CGCGCCCTGT GCCTGAATCC GGAAGTCATC CTGCTGGACG AAATCACCGC


 


501
CGCACTTGAC CCCGAAATGG TGCGCGAAGT CTTGGAAGTG GTTTTGGAAC


 


551
TCGCCCGCGA AGGGATGAGT ATGCTCATCG TAACCCACGA AATGGGGTTC


 


601
GCACGCAAAG TTGCCGACCG CATCGTCTTT ATGGACAAAG GCGGCATCGT


 


651
CGAATCGTCC GACCCCGAAA CCTTTTTTTC CGCACCAAAA AGCGAACGCG


 


701
CCCGCCAATT TCTGGCAGGT ATGGACTACT GA






This corresponds to the amino acid sequence <SEQ ID 446; ORF 122.ng>:










g122.pep




1
MALLSIRKLH KQYGSVTAIQ SLDLDLEKGE VIVLLGPSGC GKSTLLRCVN


 


51
GLEPHQGGSI VMDGVGEFGK DVSWQTARQK VGMVFQSNEL FAHMTVIENI


 


101
FLGPVKEQNR DRAEAEAQAG KLLERVGLLD RKNAYPRELS GGQKQRIAIV


 


151
RALCLNPEVI LLDEITAALD PEMVREVLEV VLELAREGMS MLIVTHEMGF


 


201
ARKVADRIVF MDKGGIVESS DPETFFSAPK SERARQFLAG MDY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 447>:










m122.seq




1
GTTGTCATGA TTAAAATCCG CAATATCCAT AAGACCTTTG GCGAAAACAC


 


51
TATTTTGCGC GGCATCGATT TGGATGTGTG CAAAGGGCAG GTGGTCGTCA


 


101
TCCTCGGGcC TTCCGGCTCA GGCAAAACGA CGTTTCTGCG ATGCCTAAAC


 


151
GCGTTGGAAA TGCCCGAAGA CGGACAAATC GAGTTCGACA ACGAGCGACC


 


201
GCTGAAAATC GATTTTTCTA AAAAACCAAG CAAACACGAT ATTTTGGCAC


 


251
TGCGCCGCAA ATCAkGCATG GTGTTTCAAC AATACAAyCT CTTTCCGCAC


 


301
AAAACCGCCT TGGAAAACGT AATGGAAGGA CCGGTTGCCG TACAgGGCAA


 


351
GCCTGCCGCC CAAGCGCGCG AAGAGGCTCT GAAACTGCTG GAAAAAGTCG


 


401
GCTTGGGCGA CAAAGTGGAT TTGTATCCCT ACCAGCTTTC CGGCGGTCAG


 


451
CAGCAGCGCG TCGGCATTGC CCGCGCATTG GCGATTCAGC CTGAACTGAT


 


501
GCTGTTTGAC GAACCGACTT CCGCGCTCGA TCCTGAATTG GTGCAAGATG


 


551
TTTTGGATmC CATGAAGGAA TTGGCGCAAG AAGGCTGGAC CATGGTTGTC


 


601
GTTACGCATG AAATCAAGTT CGCCTTAGAA GTGGCAACCA CCGwCGTCGT


 


651
GATGGACrGC GGCGTTATTG TCGAACAAGG CAGCCCGCAA GATTTGTTCG


 


701
ACCACCCCAA ACACGAACGG ACGCGGAGAT TTTTAAGCCA AATCCAATCT


 


751
ACCAAGATTT GA






This corresponds to the amino acid sequence <SEQ ID 448; ORF 122>:










m122.pep




1
VVMIKIRNIH KTFGENTILR GIDLDVCKGQ VVVILGPSGS GKTTFLRCLN


 


51
ALEMPEDGQI EFDNERPLKI DFSKKPSKHD ILALRRKSXM VFQQYNLFPH


 


101
KTALENVMEG PVAVQGKPAA QAREEALKLL EKVGLGDKVD LYPYQLSGGQ


 


151
QQRVGIARAL AIQPELMLFD EPTSALDPEL VQDVLDXMKE LAQEGWTMVV


 


201
VTHEIKFALE VATTXVVMDX GVIVEQGSPQ DLFDHPKHER TRRFLSQIQS


 


251
TKI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 122 shows 47.2% identity over a 246 aa overlap with a predicted ORF (ORF 122.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 449>:










a122.seq




1
GTTGTCATGA TTAAAATCCG CAATATCCAT AAGACCTTCG GCAAAAATAC


 


51
CATTTTGCGC GGCATCAATT TGGATGTGTG CAAAGGGCAG GTGGTCGTCA


 


101
TCCTCGGGCC TTCCGGCTCA GGCAAAACGA CGTTTCTGCG ATGCCTAAAC


 


151
GCGTTGGAAA TGCCCGAAGA CGGACAAATC GAGTTCGACA ACGAGCGACC


 


201
GCTGAAAATC GATTTTTCTA AAAAACCAAG CAAACACGAT ATTTTGGCAC


 


251
TGCGCCGCAA ATCAGGCATG GTGTTTCAAC AATACAACCT CTTTCCGCAC


 


301
AAAACCGCCT TGGAAAACGT GATGGAAGGA CCGGTTGCCG TACAGGGCAA


 


351
GCCTGCCGCC CAAGCGCGCG AAGAGGCTCT GAAACTGCTG GAAAAAGTCG


 


401
GCTTGGGCGA CAAAGTGGAT TTGTATCCCT ACCAGCTTTC CGGCGGTCAG


 


451
CAGCAGCGCG TCGGCATTGC CCGAGCATTG GCGATTCAGC CCGAGCTGAT


 


501
GTTGTTTGAC GAACCCACTT CCGCGCTTGA CCCCGAGTTG GTGCAAGACG


 


551
TGTTGAACGC CATGAAGGAA TTGGCGCGGG AAGGTTGGAC GATGGTCGTC


 


601
GTTACCCACG AAATCAAGTT CGCGCTGGAA GTTGCCACGA CCGTTGTCGT


 


651
GATGGACGGC GGCGTTATCG TAGAGCAGGG CAGCCCGAAA GAGTTGTTCG


 


701
ACCACCCCAA ACACGAACGG ACGCGGAGAT TTTTAAGCCA AATCCAATCT


 


751
ACCAAGATTT GA






This corresponds to the amino acid sequence <SEQ ID 450; ORF 122.a>:










a122.pep




1
VVMIKIRNIH KTFGKNTILR GINLDVCKGQ VVVILGPSGS GKTTFLRCLN


 


51
ALEMPEDGQI EFDNERPLKI DFSKKPSKHD ILALRRKSGM VFQQYNLFPH


 


101
KTALENVMEG PVAVQGKPAA QAREEALKLL EKVGLGDKVD LYPYQLSGGQ


 


151
QQRVGIARAL AIQPELMLFD EPTSALDPEL VQDVLNAMKE LAREGWTMVV


 


201
VTHEIKFALE VATTVVVMDG GVIVEQGSPK ELFDHPKHER TRRFLSQIQS


 


251
TKI*






m122/a122 96.0% identity in 253 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 451>:










g122-1.seq




1
ATGATTAAAA TCCGCAATAT CCATAAGACC TTTGGCGAAA ACACCATTTT


 


51
GCGCGGCATC GATTTGGATG TGGGCAAAGG GCAGGTGGTC GTCATCCTCG


 


101
GGCCTTCCGG CTCGGGTAAA ACAACATTTC TGCGCTGCCT AAACGCGTTG


 


151
GAAATGCCCG AAGACGGACA AATCGAGTTC GACAACGCGC GGCCGTTACG


 


201
CATTGATTTT TCCAAAAAAA CAAGCAAACA CGATATTTTG GCACTGCGCC


 


251
GCAAGTCCGG AATGGTATTC CAACAATACA ACCTCTTCCC GCATAAAACC


 


301
GTGTTGGAAA ACGTGATGGA AGGGCCGGTT GCCGTACAGG GCAAGCCTGC


 


351
CGCCCAAGCG CGCGAAGAGG CTTTGAAACT GCTGGAAAAA GTCGGCTTGG


 


401
GCGATAAAGT GGATTTGTAT CCCTACCAGC TTTCCGGCGG TCAGCAGCAG


 


451
CGTGTCGGTA TCGCCCGCGC ACTGGCGATT CAGCCTGAAT TGATGCTGTT


 


501
TGACGAACCC ACTTCCGCGC TGGACCCCGA GTTGGTGCAA GACGTGTTGG


 


551
ACGCCATGAA GGAATTGGCG CGGGAAGGTT GGACGATGGT CGTCGTTACC


 


601
CACGAAATCA AGTTCACGCT GGAAGTTGCC ACGAACGTCG TCGTGATGGA


 


651
CGGCGGCGTT ATCGTAGAGC AGGGCAGCCC GAAAGAGTTG TTCGACCACC


 


701
TCAAACACGA ACGGACGCGG AGATTTTTAA GCCAAATCCA ATCTGCCAAG


 


751
ATTTGA






This corresponds to the amino acid sequence <SEQ ID 452; ORF 122-1.ng>:










g122-1.pep




1
MIKIRNIHKT FGENTILRGI DLDVGKGQVV VILGPSGSGK TTFLRCLNAL


 


51
EMPEDGQIEF DNARPLRIDF SKKTSKHDIL ALRRKSGMVF QQYNLFPHKT


 


101
VLENVMEGPV AVQGKPAAQA REEALKLLEK VGLGDKVDLY PYQLSGGQQQ


 


151
RVGIARALAI QPELMLFDEP TSALDPELVQ DVLDAMKELA REGWTMVVVT


 


201
HEIKFTLEVA TNVVVMDGGV IVEQGSPKEL FDHLKHERTR RFLSQIQSAK


 


251
I*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 453>:










m122-1.seq




1
ATGATTAAAA TCCGCAATAT CCATAAGACC TTTGGCGAAA ACACTATTTT


 


51
GCGCGGCATC GATTTGGATG TGTGCAAAGG GCAGGTGGTC GTCATCCTCG


 


101
GGCCTTCCGG CTCAGGCAAA ACGACGTTTC TGCGATGCCT AAACGCGTTG


 


151
GAAATGCCCG AAGACGGACA AATCGAGTTC GACAACGAGC GACCGCTGAA


 


201
AATCGATTTT TCTAAAAAAC CAAGCAAACA CGATATTTTG GCACTGCGCC


 


251
GCAAATCAGG CATGGTGTTT CAACAATACA ACCTCTTTCC GCACAAAACC


 


301
GCCTTGGAAA ACGTAATGGA AGGACCGGTT GCCGTACAGG GCAAGCCTGC


 


351
CGCCCAAGCG CGCGAAGAGG CTCTGAAACT GCTGGAAAAA GTCGGCTTGG


 


401
GCGACAAAGT GGATTTGTAT CCCTACCAGC TTTCCGGCGG TCAGCAGCAG


 


451
CGCGTCGGCA TTGCCCGCGC ATTGGCGATT CAGCCTGAAC TGATGCTGTT


 


501
TGACGAACCG ACTTCCGCGC TCGATCCTGA ATTGGTGCAA GATGTTTTGG


 


551
ATACCATGAA GGAATTGGCG CAAGAAGGCT GGACCATGGT TGTCGTTACG


 


601
CATGAAATCA AGTTCGCCTT AGAAGTGGCA ACCACCGTCG TCGTGATGGA


 


651
CGGCGGCGTT ATTGTCGAAC AAGGCAGCCC GCAAGATTTG TTCGACCACC


 


701
CCAAACACGA ACGGACGCGG AGATTTTTAA GCCAAATCCA ATCTACCAAG


 


751
ATTTGA






This corresponds to the amino acid sequence <SEQ ID 454; ORF 122-1>:










m122-1.pep




1
MIKIRNIHKT FGENTILRGI DLDVCKGQVV VILGPSGSGK TTFLRCLNAL


 


51
EMPEDGQIEF DNERPLKIDF SKKPSKHDIL ALRRKSGMVF QQYNLFPHKT


 


101
ALENVMEGPV AVQGKPAAQA REEALKLLEK VGLGDKVDLY PYQLSGGQQQ


 


151
RVGIARALAI QPELMLFDEP TSALDPELVQ DVLDTMKELA QEGWTMVVVT


 


201
HEIKFALEVA TTVVVMDGGV IVEQGSPQDL FDHPKHERTR RFLSQIQSTK


 


251
I*






m122-1/g122-1 94.8% identity in 251 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 455>:










a122-1.seq




1
ATGATTAAAA TCCGCAATAT CCATAAGACC TTCGGCAAAA ATACCATTTT


 


51
GCGCGGCATC AATTTGGATG TGTGCAAAGG GCAGGTGGTC GTCATCCTCG


 


101
GGCCTTCCGG CTCAGGCAAA ACGACGTTTC TGCGATGCCT AAACGCGTTG


 


151
GAAATGCCCG AAGACGGACA AATCGAGTTC GACAACGAGC GACCGCTGAA


 


201
AATCGATTTT TCTAAAAAAC CAAGCAAACA CGATATTTTG GCACTGCGCC


 


251
GCAAATCAGG CATGGTGTTT CAACAATACA ACCTCTTTCC GCACAAAACC


 


301
GCCTTGGAAA ACGTGATGGA AGGACCGGTT GCCGTACAGG GCAAGCCTGC


 


351
CGCCCAAGCG CGCGAAGAGG CTCTGAAACT GCTGGAAAAA GTCGGCTTGG


 


401
GCGACAAAGT GGATTTGTAT CCCTACCAGC TTTCCGGCGG TCAGCAGCAG


 


451
CGCGTCGGCA TTGCCCGAGC ATTGGCGATT CAGCCCGAGC TGATGTTGTT


 


501
TGACGAACCC ACTTCCGCGC TTGACCCCGA GTTGGTGCAA GACGTGTTGA


 


551
ACGCCATGAA GGAATTGGCG CGGGAAGGTT GGACGATGGT CGTCGTTACC


 


601
CACGAAATCA AGTTCGCGCT GGAAGTTGCC ACGACCGTTG TCGTGATGGA


 


651
CGGCGGCGTT ATCGTAGAGC AGGGCAGCCC GAAAGAGTTG TTCGACCACC


 


701
CCAAACACGA ACGGACGCGG AGATTTTTAA GCCAAATCCA ATCTACCAAG


 


751
ATTTGA






This corresponds to the amino acid sequence <SEQ ID 456; ORF 122-1.a>:










a122-1.pep




1
MIKIRNIHKT FGKNTILRGI NLDVCKGQVV VILGPSGSGK TTFLRCLNAL


 


51
EMPEDGQIEF DNERPLKIDF SKKPSKHDIL ALRRKSGMVF QQYNLFPHKT


 


101
ALENVMEGPV AVQGKPAAQA REEALKLLEK VGLGDKVDLY PYQLSGGQQQ


 


151
RVGIARALAI QPELMLFDEP TSALDPELVQ DVLNAMKELA REGWTMVVVT


 


201
HEIKFALEVA TTVVVMDGGV IVEQGSPKEL FDHPKHERTR RFLSQIQSTK


 


251
I*






a122-1/m122-1 97.2% identity in 251 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 457>:










g125.seq




1
ATGTCGGGCA ATGCCTCCTC TCCTTCATCT TCCGCCGCCA TCGGGCTGGT


 


51
TTGGTTCGGC GCGGCGGTAT CGATTGCCGA AATCAGCACG GGTACGCTGC


 


101
TCGCCCCCTT GGGCTGGCAG CGCGGTCTGG CGGCCCTGCT TTTGGGTCAT


 


151
GCCGTCGGCG GCGCGCTGTT TTTTGCGGCG GCGTATATCG GCGCACTGAC


 


201
CGGACGCAGC TCGATGGAAA GTGTGCGCCT GTCGTTCGGC AAATGCGGTT


 


251
CAGTGCTGTT TTCCGTGGCG AATATGCTGC AACTGGCCGG CTGGACGGCG


 


301
GTGATGATTT ACGTCGGCGC AacggTCAGC TCCGCTTTGG GCAAAGTGTT


 


351
GTGGGACggc gaATCCTTTG TCTGGTGGGC ATTGGCAAAC GGCGCACTGA


 


401
TCGTGCTGTG GCTGGTTTTC GGCGCACGCA GAACGGGCGG GCTGAAAACC


 


451
GTTTCGATGC TGCTGATGCT GCTTGCCGTG TTGTGGTTGA GCGTCGAAGT


 


501
GTTCGCTTCG TCCGGCACAA ACGCCGCGCC CGCCGTTTCA GACGGCATGA


 


551
CCTTCGGAAC GGCAGTCGAA CTGTCCGCCG TCATGCCGCT TTCCTGGCTG


 


601
CCGCTGGCCG CCGACTACAC GCGCCAAGCA CGCCGCCCGT TTGCGGCAAC


 


651
CCTGACGGCA ACGCTCGCCT ATACGCTGAC GGGCTGCTGG ATGTATGCCT


 


701
TGGGTTTGGC GGCGGCTCTG TTTACCGGAG AAACCGACGT GGCGAAAATC


 


751
CTGTTGGGCG CGGGCTTGGG CATAACGGGC ATTCTGGCAG TCGTCCTCTC


 


801
CACCGTTACC ACAACGTTTC TCGATACCTA TTCCGCCGGC GCGAGTGCGA


 


851
ACAACATTTC CGCGCGTTTT GCGGAAATAC CCGTCGCTGT CGGCGTTACC


 


901
CTGatccgca ccgtgcttgc cgtcatgctg cccgttaccg aatataaaaa


 


951
cttcctgctg cttatccgct cggtatttgg gccgatggcg ggtggttttg


 


1001
attgccgaCT TTTttgtctt AAAACGGCGT GA






This corresponds to the amino acid sequence <SEQ ID 458; ORF 125.ng>:

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 459>:










m125.seq




1
ATGTCGGGCA ATGCCTCCTC TCCTTCATCT TCCTCCGCCA TCGGGCTGAT


 


51
TTGGTTCGGC GCGGCGGTAT CGATTGCCGA AATCAGCACG GGTACGCTGC


 


101
TTGCGCCTTT GGGCTGGCAG CGCGGTCTGG CGGCTCTACT TTTGGGTCAT


 


151
GCCGTCGGCG GCGCGCTGTT TTTTGCGGCG GCGTATATCG GCGCACTGAC


 


201
CGGACGCAGC TCGATGGAAA GCGTGCGCCT GTCGTTCGGC AAACGCGGTT


 


251
CAGTGCTGTT TTCCGTGGCG AATATGCTGC AACTGGCCGG CTGGACGGCG


 


301
GTGATGATTT ACGCCGGCGC AACGGTCAGC TCCGCTTTGG GCAAAGTGTT


 


351
GTGGGACGGC GAATCTTTTG TCTGGTGGGC ATTGGCAAAC GGCGCGCTGA


 


401
TTGTGCTGTG GCTGGTTTTC GGCGCACGCA AAACAGGCGG GCTGAAAACC


 


451
GTTTCGATGC TGCTGATGCT GTTGGCGGTT CTGTGGCTGA GTGCCGAAGT


 


501
CTTTTCCACG GCAGGCAGCA CCGCCGCACA GGTTTCAGAC GGCATGAGTT


 


551
TCGGAACGGC AGTCGAGCTG TCCGCCGTGA TGCCGCTTTC CTGGCTGCCG


 


601
CTTGCCGCCG ACTACACGCG CCACGCGCGC CGCCCGTTTG CGGCAACCCT


 


651
GACGGCAACG CTCGCCTACA CGCTGACCGG CTGCTGGATG TATGCCTTGG


 


701
GTTTGGCAGC GGCGTTGTTC ACCGGAGAAA CCGACGTGGC AAAAATCCTG


 


751
CTGGGCGCAr GTTTGgGTGC GGCAGGCATT TTGGCGGTCG TCCTCTCCAC


 


801
CGTTACCACA ACGTTTCTCG ATGCCTATTC CGCCGGCGCG AGTGCGAACA


 


851
ACATTTCCGC GCGTTTTGCG GAAACACCCG TCGCTGTCrG CGTTACCCTG


 


901
ATCGGCACGG TACTTGCCGT CATGCTGCCC GTTACCGAAT ATGAAAACTT


 


951
CCTGCTGCTT ATCGGCTCGG TATTTGCGCC GATGGCGGgC GGTTTTGATT


 


1001
GCCGACTTTT TCGTCTTGAA ACGGCGTGA






This corresponds to the amino acid sequence <SEQ ID 460; ORF 125>:










m125.pep




1
MSGNASSPSS SSAIGLIWFG AAVSIAEIST GTLLAPLGWQ RGLAALLLGH


 


51
AVGGALFFAA AYIGALTGRS SMESVRLSFG KRGSVLFSVA NMLQLAGWTA


 


101
VMIYAGATVS SALGKVLWDG ESFVWWALAN GALIVLWLVF GARKTGGLKT


 


151
VSMLLMLLAV LWLSAEVFST AGSTAAQVSD GMSFGTAVEL SAVMPLSWLP


 


201
LAADYTRHAR RPFAATLTAT LAYTLTGCWM YALGLAAALF TGETDVAKIL


 


251
LGAXLGAAGI LAVVLSTVTT TFLDAYSAGA SANNISARFA ETPVAVXVTL


 


301
IGTVLAVMLP VTEYENFLLL IGSVFAPMAG GFDCRLFRLE TA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 125 shows 92.1% identity over a 343 aa overlap with a predicted ORF (ORF 125.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 461>:










a125.seq




1
ATGTCGGGCA ATGCCTCCTC TCCTTCATCT TCCGCCGCCA TCGGGCTGAT


 


51
TTGGTTCGGC GCGGCGGTAT CGATTGCCGA AATCAGCACG GGTACACTGC


 


101
TTGCGCCTTT GGGCTGGCAG CGCGGTCTGG CGGCTCTGCT TTTGGGTCAT


 


151
GCCGTCGGCG GCGCGCTGTT TTTTGCGGCG GCGTATATCG GCGCACTGAC


 


201
CGGACGCAGC TCGATGGAAA GCGTGCGCCT GTCGTTCGGC AAACGCGGTT


 


251
CAGTGCTGTT TTCCGTGGCG AATATGCTGC AACTGGCCGG CTGGACGGCG


 


301
GTGATGATTT ACGCCGGCGC AACGGTCAGC TCCGCTTTGG GCAAAGTGTT


 


351
GTGGGACGGC GAATCTTTTG TCTGGTGGGC ATTGGCAAAC GGCGCGCTGA


 


401
TTGTGCTGTG GCTGGTTTTC GGCGCACGCA AAACAGGCGG GCTGAAAACC


 


451
GTTTCGATGC TGCTGATGCT GTTGGCGGTT CTGTGGCTGA GTGCCGAAGT


 


501
CTTTTCCACG GCAGGCAGCA CCGCCGCACA GGTTTCAGAC GGCATGAGTT


 


551
TCGGAACGGC AGTCGAGCTG TCCGCCGTGA TGCCGCTTTC TTGGCTGCCG


 


601
CTGGCCGCCG ACTACACGCG CCACGCGCGC CGCCCGTTTG CGGCAACCCT


 


651
GACGGCAACG CTCGCCTACA CGCTGACCGG CTGCTGGATG TATGCCTTGG


 


701
GTTTGGCAGC GGCGTTGTTC ACCGGAGAAA CCGACGTGGC AAAAATCCTG


 


751
CTGGGCGCAG GTTTGGGTGC GGCAGGCATT TTGGCGGTCG TCCTGTCGAC


 


801
CGTTACCACC ACTTTTCTCG ATGCCTACTC CGCCGGCGTA AGTGCCAACA


 


851
ATATTTCCGC CAAACTTTCG GAAATACCCA TCGCCGTTGC CGTCGCCGTT


 


901
GTCGGCACAC TGCTTGCCGT CCTCCTGCCC GTTACCGAAT ATGAAAACTT


 


951
CCTGCTGCTT ATCGGCTCGG TATTTGCGCC GATGGCG.GC GGTTTTGATT


 


1001
GCCGACTTTT TCGTCTTGAA ACGGCGTGA






This corresponds to the amino acid sequence <SEQ ID 462; ORF 125.a>:










a125.pep




1
MSGNASSPSS SAAIGLIWFG AAVSIAEIST GTLLAPLGWQ RGLAALLLGH


 


51
AVGGALFFAA AYIGALTGRS SMESVRLSFG KRGSVLFSVA NMLQLAGWTA


 


101
VMIYAGATVS SALGKVLWDG ESFVWWALAN GALIVLWLVF GARKTGGLKT


 


151
VSMLLMLLAV LWLSAEVFST AGSTAAQVSD GMSFGTAVEL SAVMPLSWLP


 


201
LAADYTRHAR RPFAATLTAT LAYTLTGCWM YALGLAAALF TGETDVAKIL


 


251
LGAGLGAAGI LAVVLSTVTT TFLDAYSAGV SANNISAKLS EIPIAVAVAV


 


301
VGTLLAVLLP VTEYENFLLL IGSVFAPMAX GFDCRLFRLE TA*






m125/a125 95.6% identity in 342 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 463>:










g126.seq




1
AtgccgtcTG AAaccCcaaa ggcACGCCGC CGGCTTTCAG ACGGCATCGC


 


51
GTCCGACAAC CATACCAAAG AATCCATCAT GCTCACCctg tacggcGAAA


 


101
CTTTCCCTTC GCGGCTGCTg ctcggcacgG cggcctacCC GACCCCTGAA


 


151
ATCCTCAAAC AATCCGTCCG AACCGCCCGG CCCGCGATGA ttaccGTCTC


 


201
GCTGCGCCGC ACGGGATGCG GCGGCGAGGC GCACGGTCAG GGGTTTTGGT


 


251
CGCTGCTTCA AGAAACCGGC GTTCCCGTCC TGCCGAACAC GGCAGGCTGC


 


301
CAAAGCGTGC AGGAAGCGGT AACGACGGCG CAAATGGCGC GCGAAGTGTT


 


351
TGAAACCGAT TGGATAAAAT TGGAACTCAT CGGCGACGAC GACACCTTGC


 


401
AGCCGGACGT GTTCCAACTC GTCGAAGCGG CGGAAATCCT GATTAAAGAC


 


451
GGCTTCAAAG TGCTGCCTTA TTGCACCGAA GACCTGATTG CCTGCCGCCG


 


501
CCTGCTCGAT GCGGGCTGTC AGGCGTTGAT GCCGTGGGCG GCTCCCATCG


 


551
GCACGGGTTT GGGGGCGGTT CACGCCTATG CGCTCAAAAT CCTGCGCGAA


 


601
CGCCTGCCCG ACACGCCGCT GATTATCGAC GCGGGCTTGG GTTTGCCTTC


 


651
CCAAGCGGCA CAAGTGATGG AATGGGGTTT TGACGGCGTA TTGTTAAACA


 


701
CCGCCGTTTC CCGCAGCGGC GACCCCGTCA ACATGGCGCG CGCCTTCGCA


 


751
CTCGCCGTCG AATCCGGACG GCTGGCATTT GAAGCCGGGC CGGTCGAAGC


 


801
GCGAACCAAA GCCCAAGCCA GCACGCCGAC AGTCGGACAA CCGTTTTGGC


 


851
ATTCGGCGGA ATATTGA






This corresponds to the amino acid sequence <SEQ ID 464; ORF 126.ng>:










g126.pep




1
MPSETPKARR RLSDGIASDN HTKESIMLTL YGETFPSRLL LGTAAYPTPE


 


51
ILKQSVRTAR PAMITVSLRR TGCGGEAHGQ GFWSLLQETG VPVLPNTAGC


 


101
QSVQEAVTTA QMAREVFETD WIKLELIGDD DTLQPDVFQL VEAAEILIKD


 


151
GFKVLPYCTE DLIACRRLLD AGCQALMPWA APIGTGLGAV HAYALKILRE


 


201
RLPDTPLIID AGLGLPSQAA QVMEWGFDGV LLNTAVSRSG DPVNMARAFA


 


251
LAVESGRLAF EAGPVEARTK AQASTPTVGQ PFWHSAEY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 465>:









m126.seq (partial)










1
..CACTATACAA AGGAACCCAT TATGCTCACC CTATACGGCG AAACTTTCCC



 


51
  CTCGCGGCTG CTGCTCGGCA CGGCTGCCTA CCCGACCCCC GAAATCCTCA


 


101
  AACAATCCAT CCAAACCGCC CAGCCTGCGA TGATTACCGT CTCGCTGCGC


 


151
  CGCGCGGGAA GCGGCGGCGA GGCGCACGGT CAGGGGTTTT GGTCGCTGCT


 


201
  TCAAGAAACC GGCGTTCCCG TCCTGCCGAA CACGGCAGGC TGCCAAAGCG


 


251
  TGCAGGAAGC GGTAACGACG GCGCAAATGG CGCGCGAAGT GTTTGAAACC


 


301
  GATTGGATAA AATTGGAACT CATCGGAGAT GACGACACCT TGCAGCCGGA


 


351
  TGTGTTCCAG CTTGTCGAAG CGGCGGAAAT CCTGATTAAA GACGGCTTCA


 


401
  AAGTGCTGCC TTATTGCACC GAAGACCTGA TTGCCTGCCG CCGCCTGCTC


 


451
  GACGCGGGCT GTCAGGCGTT GATGCCGTGG GCGGCCCCGA TCGGCACGGG


 


501
  TTTGGGCGCG GTTCACGCCT ACGCGTTGAA CGTCCTGCGC GAACGCCTGC


 


551
  CCGACACGCC GCTGATTATC GACGCGGGCT TGGGTTTGCC CTCACAGGCG


 


601
  GCACAAGTGA TGGAATGGGG CTTTGACGGC GTGCTTTTGA ATACTGCCGT


 


651
  TTCCCGCAGC GGCGATCCGG TCAATATGGC ACGCGCCTTC GCACTCGCCG


 


701
  TCGAATCCGG ACGGCTGGCA TTTGAAGCCG GACCGGTCGA AGCACGCGAC


 


751
  AAAGCGCAAG CCAGCACGCC GACAGTCGGA CAACCGTTTT GGCATTCGGC


 


801
  GGAATATTGA






This corresponds to the amino acid sequence <SEQ ID 466; ORF 126>:









m126.pep (partial)










1
..HYTKEPIMLT LYGETFPSRL LLGTAAYPTP EILKQSIQTA QPAMITVSLR



 


51
  RAGSGGEAHG QGFWSLLQET GVPVLPNTAG CQSVQEAVTT AQMAREVFET


 


101
  DWIKLELIGD DDTLQPDVFQ LVEAAEILIK DGFKVLPYCT EDLIACRRLL


 


151
  DAGCQALMPW AAPIGTGLGA VHAYALNVLR ERLPDTPLII DAGLGLPSQA


 


201
  AQVMEWGFDG VLLNTAVSRS GDPVNMARAF ALAVESGRLA FEAGPVEARD


 


251
  KAQASTPTVG QPFWHSAEY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 126 shows 95.9% identity over a 269 aa overlap with a predicted ORF (ORF 126.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 467>:










a126.seq




1
TTGTTAATCC ACTATACAAA GGAACCCATT ATGCTCACCC TGTACAGCGA


 


51
AACTTTCCCT TCGCGGCTGC TGCTCGGCAC AGCCGCCTAC CCGACCCCTG


 


101
AAATCCTCAA ACAATCCGTC CGAACCGCCC GGCCCGCGAT GATTACCGTC


 


151
TCGCTGCGCC GCGCGGGATG CGGCGGCGAG GCGCACGGTC AGGGGTTTTG


 


201
GTCGCTGCTT CAAGAAACCG GCGTTCCCGT CCTGCCGAAC ACGGCAGGCT


 


251
GCCAAAGCGT GCAGGAAGCG GTAACGACGG CGCAAATGGC GCGCGAAGTG


 


301
TTTGAAACCG ATTGGATTAA ACTCGAACTC ATCGGCGACG ACGACACCTT


 


351
GCAGCCGGAT GTGTTCCAAC TTGTCGAAGC GGCGGAAATC CTGATTAAAG


 


401
ACGGCTTCAA AGTGCTGCCT TATTGCACCG AAGACCTGAT TGCCTGCCGC


 


451
CGCCTGCTCG ACGCGGGCTG TCAGGCGTTG ATGCCGTGGG CGGCCCCGAT


 


501
CGGCACGGGT TTGGGCGCGG TTCACGCCTA CGCGTTGAAC GTCCTGCGCG


 


551
AACGCCTGCC CGACACGCCG CTGATTATCG ACGCGGGCTT GGGTTTGCCC


 


601
TCACAGGCGG CACAAGTGAT GGAATGGGGC TTTGACGGCG TGCTTTTGAA


 


651
TACTGCCGTT TCCCGCAGCG GCGATCCGGT CAATATGGCA CGCGCCTTCG


 


701
CACTCGCCGT CGAATCCGGA CGGCTGGCAT TTGAAGCCGG ACCGGTCGAA


 


751
GCACGCGACA AAGCGCAAGC CAGCACGCCG ACAGTCGGAC AACCGTTTTG


 


801
GCATTCGGCG GAATATTGA






This corresponds to the amino acid sequence <SEQ ID 468; ORF 126.a>:










a126.pep




1
LLIHYTKEPI MLTLYSETFP SRLLLGTAAY PTPEILKQSV RTARPAMITV


 


51
SLRRAGCGGE AHGQGFWSLL QETGVPVLPN TAGCQSVQEA VTTAQMAREV


 


101
FETDWIKLEL IGDDDTLQPD VFQLVEAAEI LIKDGFKVLP YCTEDLIACR


 


151
RLLDAGCQAL MPWAAPIGTG LGAVHAYALN VLRERLPDTP LIIDAGLGLP


 


201
SQAAQVMEWG FDGVLLNTAV SRSGDPVNMA RAFALAVESG RLAFEAGPVE


 


251
ARDKAQASTP TVGQPFWHSA EY*






m126/a126 98.1% identity in 269 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 469>:










g126-1.seq




1
ATGCTCACCC TGTACGGCGA AACTTTCCCT TCGCGGCTGC TGCTCGGCAC


 


51
GGCCGCCTAC CCGACCCCTG AAATCCTCAA ACAATCCGTC CGAACCGCCC


 


101
GGCCCGCGAT GATTACCGTC TCGCTGCGCC GCACGGGATG CGGCGGCGAG


 


151
GCGCACGGTC AGGGGTTTTG GTCGCTGCTT CAAGAAACCG GCGTTCCCGT


 


201
CCTGCCGAAC ACGGCAGGCT GCCAAAGCGT GCAGGAAGCG GTAACGACGG


 


251
CGCAAATGGC GCGCGAAGTG TTTGAAACCG ATTGGATAAA ATTGGAACTC


 


301
ATCGGCGACG ACGACACCTT GCAGCCGGAC GTGTTCCAAC TCGTCGAAGC


 


351
GGCGGAAATC CTGATTAAAG ACGGCTTCAA AGTGCTGCCT TATTGCACCG


 


401
AAGACCTGAT TGCCTGCCGC CGCCTGCTCG ATGCGGGCTG TCAGGCGTTG


 


451
ATGCCGTGGG CGGCTCCCAT CGGCACGGGT TTGGGGGCGG TTCACGCCTA


 


501
TGCGCTCAAA ATCCTGCGCG AACGCCTGCC CGACACGCCG CTGATTATCG


 


551
ACGCGGGCTT GGGTTTGCCT TCCCAAGCGG CACAAGTGAT GGAATGGGGT


 


601
TTTGACGGCG TATTGTTAAA CACCGCCGTT TCCCGCAGCG GCGACCCCGT


 


651
CAACATGGCG CGCGCCTTCG CACTCGCCGT CGAATCCGGA CGGCTGGCAT


 


701
TTGAAGCCGG GCCGGTCGAA GCGCGAACCA AAGCCCAAGC CAGCACGCCG


 


751
ACAGTCGGAC AACCGTTTTG GCATTCGGCG GAATATTGA






This corresponds to the amino acid sequence <SEQ ID 470; ORF 126-1.ng>:










g126-1.pep




1
MLTLYGETFP SRLLLGTAAY PTPEILKQSV RTARPAMITV SLRRTGCGGE


 


51
AHGQGFWSLL QETGVPVLPN TAGCQSVQEA VTTAQMAREV FETDWIKLEL


 


101
IGDDDTLQPD VFQLVEAAEI LIKDGFKVLP YCTEDLIACR RLLDAGCQAL


 


151
MPWAAPIGTG LGAVHAYALK ILRERLPDTP LIIDAGLGLP SQAAQVMEWG


 


201
FDGVLLNTAV SRSGDPVNMA RAFALAVESG RLAFEAGPVE ARTKAQASTP


 


251
TVGQPFWHSA EY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 471>:










m126-1.seq




1
ATGCTCACCC TATACGGCGA AACTTTCCCC TCGCGGCTGC TGCTCGGCAC


 


51
GGCTGCCTAC CCGACCCCCG AAATCCTCAA ACAATCCATC CAAACCGCCC


 


101
AGCCTGCGAT GATTACCGTC TCGCTGCGCC GCGCGGGAAG CGGCGGCGAG


 


151
GCGCACGGTC AGGGGTTTTG GTCGCTGCTT CAAGAAACCG GCGTTCCCGT


 


201
CCTGCCGAAC ACGGCAGGCT GCCAAAGCGT GCAGGAAGCG GTAACGACGG


 


251
CGCAAATGGC GCGCGAAGTG TTTGAAACCG ATTGGATAAA ATTGGAACTC


 


301
ATCGGAGATG ACGACACCTT GCAGCCGGAT GTGTTCCAGC TTGTCGAAGC


 


351
GGCGGAAATC CTGATTAAAG ACGGCTTCAA AGTGCTGCCT TATTGCACCG


 


401
AAGACCTGAT TGCCTGCCGC CGCCTGCTCG ACGCGGGCTG TCAGGCGTTG


 


451
ATGCCGTGGG CGGCCCCGAT CGGCACGGGT TTGGGCGCGG TTCACGCCTA


 


501
CGCGTTGAAC GTCCTGCGCG AACGCCTGCC CGACACGCCG CTGATTATCG


 


551
ACGCGGGCTT GGGTTTGCCC TCACAGGCGG CACAAGTGAT GGAATGGGGC


 


601
TTTGACGGCG TGCTTTTGAA TACTGCCGTT TCCCGCAGCG GCGATCCGGT


 


651
CAATATGGCA CGCGCCTTCG CACTCGCCGT CGAATCCGGA CGGCTGGCAT


 


701
TTGAAGCCGG ACCGGTCGAA GCACGCGACA AAGCGCAAGC CAGCACGCCG


 


751
ACAGTCGGAC AACCGTTTTG GCATTCGGCG GAATATTGA






This corresponds to the amino acid sequence <SEQ ID 5; ORF 126-1>:










m126-1.pep




1
MLTLYGETFP SRLLLGTAAY PTPEILKQSI QTAQPAMITV SLRRAGSGGE


 


51
AHGQGFWSLL QETGVPVLPN TAGCQSVQEA VTTAQMAREV FETDWIKLEL


 


101
IGDDDTLQPD VFQLVEAAEI LIKDGFKVLP YCTEDLIACR RLLDAGCQAL


 


151
MPWAAPIGTG LGAVHAYALN VLRERLPDTP LIIDAGLGLP SQAAQVMEWG


 


201
FDGVLLNTAV SRSGDPVNMA RAFALAVESG RLAFEAGPVE ARDKAQASTP


 


251
TVGQPFWHSA EY*






m126-1/g126-1 96.9% identity in 262 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 473>:










a126-1.seq




1
ATGCTCACCC TGTACAGCGA AACTTTCCCT TCGCGGCTGC TGCTCGGCAC


 


51
AGCCGCCTAC CCGACCCCTG AAATCCTCAA ACAATCCGTC CGAACCGCCC


 


101
GGCCCGCGAT GATTACCGTC TCGCTGCGCC GCGCGGGATG CGGCGGCGAG


 


151
GCGCACGGTC AGGGGTTTTG GTCGCTGCTT CAAGAAACCG GCGTTCCCGT


 


201
CCTGCCGAAC ACGGCAGGCT GCCAAAGCGT GCAGGAAGCG GTAACGACGG


 


251
CGCAAATGGC GCGCGAAGTG TTTGAAACCG ATTGGATTAA ACTCGAACTC


 


301
ATCGGCGACG ACGACACCTT GCAGCCGGAT GTGTTCCAAC TTGTCGAAGC


 


351
GGCGGAAATC CTGATTAAAG ACGGCTTCAA AGTGCTGCCT TATTGCACCG


 


401
AAGACCTGAT TGCCTGCCGC CGCCTGCTCG ACGCGGGCTG TCAGGCGTTG


 


451
ATGCCGTGGG CGGCCCCGAT CGGCACGGGT TTGGGCGCGG TTCACGCCTA


 


501
CGCGTTGAAC GTCCTGCGCG AACGCCTGCC CGACACGCCG CTGATTATCG


 


551
ACGCGGGCTT GGGTTTGCCC TCACAGGCGG CACAAGTGAT GGAATGGGGC


 


601
TTTGACGGCG TGCTTTTGAA TACTGCCGTT TCCCGCAGCG GCGATCCGGT


 


651
CAATATGGCA CGCGCCTTCG CACTCGCCGT CGAATCCGGA CGGCTGGCAT


 


701
TTGAAGCCGG ACCGGTCGAA GCACGCGACA AAGCGCAAGC CAGCACGCCG


 


751
ACAGTCGGAC AACCGTTTTG GCATTCGGCG GAATATTGA






This corresponds to the amino acid sequence <SEQ ID 474; ORF 126-1.a>:










a126-1.pep




1
MLTLYSETFP SRLLLGTAAY PTPEILKQSV RTARPAMITV SLRRAGCGGE


 


51
AHGQGFWSLL QETGVPVLPN TAGCQSVQEA VTTAQMAREV FETDWIKLEL


 


101
IGDDDTLQPD VFQLVEAAEI LIKDGFKVLP YCTEDLIACR RLLDAGCQAL


 


151
MPWAAPIGTG LGAVHAYALN VLRERLPDTP LIIDAGLGLP SQAAQVMEWG


 


201
FDGVLLNTAV SRSGDPVNMA RAFALAVESG RLAFEAGPVE ARDKAQASTP


 


251
TVGQPFWHSA EY*






a126-1/m126-1 98.1% identity in 262 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 475>:










g127.seq




1
ATGGAAATAT GGAATATGTT GAACACTTGG CCCGATGCCG TCCCGATACG


 


51
CGCGGAGGCG GCCGAATCCG TGGCGGCGGT CGCGGCTTTG CTGCTGGCGC


 


101
GCGCCCTTCT GTTGAATATC CACTTCAGAC GGCATCCGGA TTTCGGCATC


 


151
GAAAGCAAGC GGCGGTTTTT GGTTGCCAGC CGCAATATAA CGCTGCTTTT


 


201
GGTGCTGTTT TCGCTGGCAT TTATCTGGTC GGCGCAAATT CAAACGCTGG


 


251
CTTTGTCGAT GTTTGCGGTG GCGGCGGCGG TCGTCGTGGC GACAAAAGAA


 


301
CTGATTATGT GTCTGTCGGG CAGTATTTTA aggtctGCCA CCCAGCAATA


 


351
CTCGGTCGGC GACTATATCG AAATCAACGG CCTGCGCGGG CGCGTGGTCG


 


401
ACATCAATCT GTTGAACACG CTGATGATGC AGGTCGGTCC GAACCCCTTG


 


451
GTCGGACAGC TTGCGGGAAC CACCGTTTCT TTCCCCAACA GCCTGTTGTT


 


501
GAGCCACCCC GTGCGCCGCG ACAATATTTT GGGCGACTAT GTCATCCATA


 


551
CGGTCGAAAT CCCCGTTCCC ATCCATTTGG ATTCGGATGA AGCCGTATGC


 


601
CGTCTGAAAG CCGTACTCGA GCCCTTGTGC GCGCCCTACA TCCCCGCCAT


 


651
TCAGCGGTAT TTGGAAAACG TGCAGGCGGA AAAACTGTTT ATCACGCCCG


 


701
CCGCCAGGCC GCGCGTTACC CGCGTACCGT ACGACGACAA GGCATACCGC


 


751
ATCATCGTCC GCTTCGCCTC CCCCGTTTCA AAGCGGCTGG AAATCCAACA


 


801
GGCGGTTATG GACGAATTTT TGCGCGTACA ATACCGCCTG TTAAATCATC


 


851
CCGCCGgctc cgAAACACTT TAA






This corresponds to the amino acid sequence <SEQ ID 476; ORF 127.ng>:










g127.pep




1
MEIWNMLNTW PDAVPIRAEA AESVAAVAAL LLARALLLNI HFRRHPDFGI


 


51
ESKRRFLVAS RNITLLLVLF SLAFIWSAQI QTLALSMFAV AAAVVVATKE


 


101
LIMCLSGSIL RSATQQYSVG DYIEINGLRG RVVDINLLNT LMMQVGPNPL


 


151
VGQLAGTTVS FPNSLLLSHP VRRDNILGDY VIHTVEIPVP IHLDSDEAVC


 


201
RLKAVLEPLC APYIPAIQRY LENVQAEKLF ITPAARPRVT RVPYDDKAYR


 


251
IIVRFASPVS KRLEIQQAVM DEFLRVQYRL LNHPAGSETL *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 477>:










m127.seq




1
ATGGAAATAT GGAATATGTT GGACACTTGG CTCGGTGCCG TCCCGATACG


 


51
TGCGGAGGCG GTCGAATCCG TGGCGGCGGT TGCGGCTTTG CTGCTGGCGC


 


101
GCGCCCTTCT GTTGAATATC CACTTCAAAC GGCATCCGGA TTTCGGCATC


 


151
GAAAGCAAGC GGCGGTTTTT GGTTGCCAGC CGCAATATAA CGCTGCTTTT


 


201
GGTGCTGTTT TCGCTGGCAT TTATCTGGTC GGCGCAAATC CAAACGCTGG


 


251
CTTTGTCGAT GTTTGCGGTG GCGGCGGCGG TCGTCGTGGC GACGAAGGAA


 


301
CTGATTATGT GTCTGTCGGG CAGTATTTTA AGGTCTGCCA CCCAGCAATA


 


351
CTCGGTCGGC GACTATATCG AAATCAACGG CCTGCGCGGG CGCGTGGTCG


 


401
ACATCAACCT GTTGAACACG CTGATGATGC AGGTCGGTCC GAACCCCTTG


 


451
GTCGGACAGC TTGCGGGAAC CACCGTTTCT TTCCCCAACA GCCTGTTGTT


 


501
GAGCCACCCC GTGCGCCGCG ACAATATTTT GGGCGACTAT GTCATCCATA


 


551
CGGTCGAAAT CCCCGTTCCC ATCCATTTGG ATTCGGATGA AGCCGTATGC


 


601
CGTCTGAAAG CCGTACTCGA GCCCTTGTGC GCGCCCTACA TCCCCGCCAT


 


651
CCAACGGsAT TTGGAAAACG TGCAGGCGGA AAAACTGTTT ATCACGCCCG


 


701
CCGCCAGACC GCGCGTTACC CGCGTGCCGT ACGATGACAA GGCATACCGC


 


751
ATCATCGTCC GCTTCGCTTC CCCCGTTTCA AAGCGGCTGG AAATCCAACA


 


801
GGCGGTTATG GACGAATTTT TGCGCGTACA ATACCGCCTG TTAAATCACC


 


851
CCGCCGGCTC CGAAACACTT TAA






This corresponds to the amino acid sequence <SEQ ID 478; ORF 127>:










m127.pep




1
MEIWNMLDTW LGAVPIRAEA VESVAAVAAL LLARALLLNI HFKRHPDFGI


 


51
ESKRRFLVAS RNITLLLVLF SLAFIWSAQI QTLALSMFAV AAAVVVATKE


 


101
LIMCLSGSIL RSATQQYSVG DYIEINGLRG RVVDINLLNT LMMQVGPNPL


 


151
VGQLAGTTVS FPNSLLLSHP VRRDNILGDY VIHTVEIPVP IHLDSDEAVC


 


201
RLKAVLEPLC APYIPAIQRX LENVQAEKLF ITPAARPRVT RVPYDDKAYR


 


251
IIVRFASPVS KRLEIQQAVM DEFLRVQYRL LNHPAGSETL *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 127 shows 97.9% identity over a 290 aa overlap with a predicted ORF (ORF 127.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 479>:










a127.seq




1
ATGGAAATAT GGAATATGTT GGACACTTGG CTCGGTGCCG TCCCGATACG


 


51
TGCGGAGGCG GTCGAATCCG TGGCGGTGGT CGCGGCTTTG CTGCTGGCGC


 


101
GCGCCCTTCT GTTGAATATC CACTTCAAAC GGCATCCGGA TTTCGGCATC


 


151
GAAAGCAAGC GGCGGTTTTT GGTTGCCAGC CGCAATATAA CGCTGCTTTT


 


201
GGTGCTGTTT TCGCTGGCAT TTATCTGGTC GGCGCAAATC CAAACGCTGG


 


251
CTTTGTCGAT GTTTGCGGTG GCGGCGGCGG TCGTCGTGGC GACGAAGGAA


 


301
CTGATTATGT GTCTGTCGGG CAGCATTTTA AGGTCTGCCA CCCAGCAATA


 


351
CTCGGTCGGC GACTATATCG AAATCAACGG CCTGCGCGGG CGCGTGGTCG


 


401
ACATCAACCT GTTGAACACG CTGATGATGC AGGTCGGTCC GAACCCCTTG


 


451
GTCGGACAGC TTGCGGGAAC CACCGTTTCT TTCCCCAACA GCCTGTTGTT


 


501
GAGCCACCCC GTGCGCCGCG ACAATATTTT GGGCGACTAC GTCATCCATA


 


551
CGGTCGAAAT CCCGGTTCCC ATCCATTTGG ATTCGGATGA AGCCGTATGC


 


601
CGTCTGAAAG CCGTACTCGA GCCCTTGTGC GCGCCCTACA TCCCCGCCAT


 


651
CCAACGGCAT TTGGAAAACG TGCAGGCGGA AAAACTGTTT ATCACGCCCG


 


701
CCGCCAAACC GCGCGTTACC CGCGTGCCGT ACGATGACAA GGCATACCGC


 


751
ATCATCGTCC GCTTCGCCTC CCCCGTTTCA AAGCGGCTGG AAATCCAACA


 


801
GGCGGTTATG GACGAATTTT TGCGCGTACA ATACCGCCTG TTAAATTACC


 


851
CCGCCGGCTC CGAAACACTT TAA






This corresponds to the amino acid sequence <SEQ ID 480; ORF 127.a>:










a127.pep




1
MEIWNMLDTW LGAVPIRAEA VESVAVVAAL LLARALLLNI HFKRHPDFGI


 


51
ESKRRFLVAS RNITLLLVLF SLAFIWSAQI QTLALSMFAV AAAVVVATKE


 


101
LIMCLSGSIL RSATQQYSVG DYIEINGLRG RVVDINLLNT LMMQVGPNPL


 


151
VGQLAGTTVS FPNSLLLSHP VRRDNILGDY VIHTVEIPVP IHLDSDEAVC


 


201
RLKAVLEPLC APYIPAIQRH LENVQAEKLF ITPAAKPRVT RVPYDDKAYR


 


251
IIVRFASPVS KRLEIQQAVM DEFLRVQYRL LNYPAGSETL *






m127/a127 98.6% identity in 290 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 481>:










g128.seq




1
atgattgaca acgCActgct ccacttgggc gaagaaccCC GTTTTaatca


 


51
aatccaaacc gaagACAtca AACCCGCCGT CCAAACCGCC ATCGCCGAAG


 


101
CGCGCGGACA AATCGCCGCC GTCAAAGCGC AAACGCACAC CGGCTGGGCG


 


151
AACACCGTCG AGCGTCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTCGTG TCCCATCTCA ACTCCGTCGT CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCTGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAACTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTTGCA ACGCTTTCCC CCGCACAAAA AACCAAGCTC GATCACGACC


 


401
TGCGCGATTT CGTATTGAGC GGCGCGGAAC TGCCGCCCGA ACGGCAGGCA


 


451
GAACTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCC


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGTTAC AAAATCGGCT TGCAGATTCC


 


651
GCACTACCTT GCCGTTATCC AATACGCCGG CAACCGCGAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGTGCCA GCGAACTTTC AAACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCATTGAA


 


801
AACCGccaaa cTGCTCGGCT TTAAAAATTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACGCCC GAACAGGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAACACCTCG GTCTCGCCGA CCCGCAGCCG TGGGACTTGA


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTTCTGGCAG GCCTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT CGCCGAAAAA ACCGTTCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCAAAACC


 


1201
ATCGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACtaca AAGGCCGCCG CCGCTTTGCC GACGgcacGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCGCCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CGCGTTTAAG CCACGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AacCGGCCAC GGACTGCACC ACCTGCTTAC CCAAGTGGAC GAACTGGGCG


 


1451
TGTCCGGCAT CAAcggcgtA GAATGGGACG CGGTCGAACT GCCCAGCCAG


 


1501
TTTATGGAAA ACTTCGTTTG GGAATACAAT GTATTGGCAC AAATGTCCGC


 


1551
CCACGAAGAA AccgGCGAGC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TcgcCGCCAA AAACTTCCAG CGCGGTATGT TCCTCGTCCG GCAAATGGAG


 


1651
TTCGCCCTCT TCGATATGAT GATTTACAGT GAAAGCGACG AATGCCGTCT


 


1701
GAAAAACTGG CAGCAGGTTT TAGACAGCGT GCGCAAAGAA GTcGCCGTCA


 


1751
TCCAACCGCC CGAATACAAC CGCTTCGCCA ACAGCTTCGG CCacatctTC


 


1801
GCcggcGGCT ATTCCGCAGG CTATTACAGC TACGCATGGG CCGAAGTCCt


 


1851
cAGCACCGAT GCCTACGCCG CCTTTGAAGA AAGcGACGac gtcGCCGCCA


 


1901
CAGGCAAACG CTTCTGGCAA GAAAtccttg ccgtcggcgg ctCCCGCAGC


 


1951
gcgGCGGAAT CCTTCAAAGC CTTCCGCGGA CGCGAACCGA GCATAGACGC


 


2001
ACTGCTGCGC CAaagcggtT TCGACAACGC gGCttgA






This corresponds to the amino acid sequence <SEQ ID 482; ORF 128.ng>:










g128.pep




1
MIDNALLHLG EEPRFNQIQT EDIKPAVQTA IAEARGQIAA VKAQTHTGWA


 


51
NTVERLTGIT ERVGRIWGVV SHLNSVVDTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFA TLSPAQKTKL DHDLRDFVLS GAELPPERQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYAGNRE LREQIYRAYV TRASELSNDG


 


251
KFDNTANIDR TLENALKTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR EHLGLADPQP WDLSYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLAGLFAQIK KLYGIGFAEK TVPVWHKDVR YFELQQNGKT


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFA DGTLQLPTAY LVCNFAPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGEPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS ESDECRLKNW QQVLDSVRKE VAVIQPPEYN RFANSFGHIF


 


601
AGGYSAGYYS YAWAEVLSTD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR QSGFDNAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 483>:









m128.seq (partial)










1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATCGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTGCGTCGC CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCCGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTCGAC ACCCTCTCCC CCGCACAAAA AACCAAACTC AACCAC


 


1
TACGCCAGCG AAAAACTGCG CGAAGCCAAA TACGCGTTCA GCGAAACCGA


 


51
wGTCAAAAAA TAyTTCCCyG TCGGCAAwGT ATTAAACGGA CTGTTCGCCC


 


101
AAmTCAAAAA ACTmTACGGC ATCGGATTTA CCGAAAAAAC yGTCCCCGTC


 


151
TGGCACAAAG ACGTGCGCTA TTkTGAATTG CAACAAAACG GCGAAmCCAT


 


201
AGGCGGCGTT TATATGGATT TGTACGCACG CGAAGGCAAA CGCGGCGGCG


 


251
CGTGGATGAA CGACTACAAA GGCCGCCGCC GTTTTTCAGA CGGCACGCTG


 


301
CAAyTGCCCA CCGCCTACCT CGTCTGCAAC TTCGCCCCAC CCGTCGGCGG


 


351
CAGGGAAGCC CGCyTGAGCC ACGACGAAAT CCTCATCCTC TTCCACGAAA


 


401
CCGGACACGG GCTGCACCAC CTGCTTACCC AAGTGGACGA ACTGGGCGTA


 


451
TCCGGCATCA ACGGCGTAkA ATGGGACGCG GTCGAACTGC CCAGCCAGTT


 


501
TATGGAAAAT TTCGTTTGGG AATACAATGT CTTGGCACAA mTGTCAGCCC


 


551
ACGAAGAAAC CGGcgTTCCC yTGCCGAAAG AACTCTTsGA CAAAwTGCTC


 


601
GCCGCCAAAA ACTTCCAAsG CGGCATGTTC yTsGTCCGGC AAwTGGAGTT


 


651
CGCCCTCTTT GATATGATGA TTTACAGCGA AGACGACGAA GGCCGTCTGA


 


701
AAAACTGGCA ACAGGTTTTA GACAGCGTGC GCAAAAAAGT CGCCGTCATC


 


751
CAGCCGCCCG AATACAACCG CTTCGCCTTG AGCTTCGGCC ACATCTTCGC


 


801
AGGCGGCTAT TCCGCAGCTn ATTACAGCTA CGCGTGGGCG GAAGTATTGA


 


851
GCGCGGACGC ATACGCCGCC TTTGAAGAAA GCGACGATGT CGCCGCCACA


 


901
GGCAAACGCT TTTGGCAGGA AATCCTCGCC GTCGGGGnAT CGCGCAGCGG


 


951
nGCAGAATCC TTCAAAGCCT TCCGCGGCCG CGAACCGAGC ATAGACGCAC


 


1001
TCTTGCGCCA CAGCGGTTTC GACAACGCGG TCTGA






This corresponds to the amino acid sequence <SEQ ID 484; ORF 128>:









m128.pep (partial)










1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA



 


51
NTVEPLTGIT ERVGRIWGVV SHLNCVADTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSPAQKTKL NH


 








//










1
YASEKLREAK YAFSETXVKK YFPVGXVLNG LFAQXKKLYG IGFTEKTVPV



 


51
WHKDVRYXEL QQNGEXIGGV YMDLYAREGK RGGAWMNDYK GRRRFSDGTL


 


101
QLPTAYLVCN FAPPVGGREA RLSHDEILIL FHETGHGLHH LLTQVDELGV


 


151
SGINGVXWDA VELPSQFMEN FVWEYNVLAQ XSAHEETGVP LPKELXDKXL


 


201
AAKNFQXGMF XVRQXEFALF DMMIYSEDDE GRLKNWQQVL DSVRKKVAVI


 


251
QPPEYNRFAL SFGHIFAGGY SAAXYSYAWA EVLSADAYAA FEESDDVAAT


 


301
GKRFWQEILA VGXSRSGAES FKAFRGREPS IDALLRHSGF DNAV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 128 shows 91.7% identity over a 475 aa overlap with a predicted ORF (ORF 128.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 485>:










a128.seq




1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATTGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTCCGTCAC CGACACGCCC GAACTGCGCG


 


251
CCGCCTACAA TGAATTAATG CCCGAAATTA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAACTCCCC


 


351
CGAGTTCGAC ACCCTCTCCC ACGCGCAAAA AACCAAACTC AACCACGATC


 


401
TGCGCGATTT CGTCCTCAGC GGCGCGGAAC TGCCGCCCGA ACAGCAGGCA


 


451
GAATTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCT


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGCTAC AAAATCGGTT TGCAGATTCC


 


651
GCACTACCTC GCCGTCATCC AATACGCCGA CAACCGCAAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGCGCCA GCGAGCTTTC AGACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCCCTGCA


 


801
AACCGCCAAA CTGCTCGGCT TCAAAAACTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACCCCC GAACAAGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAAAGCCTCG GCCTCGCCGA TTTGCAACCG TGGGACTTGG


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTATTAAACG GACTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT TACCGAAAAA ACCGTCCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCGAAACC


 


1201
ATAGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGTTTTTCA GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCACCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CCCGCTTGAG CCATGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AACCGGACAC GGCCTGCACC ACCTGCTTAC CCAAGTCGAC GAACTGGGCG


 


1451
TATCCGGCAT CAACGGCGTA GAATGGGACG CAGTCGAACT GCCCAGTCAG


 


1501
TTTATGGAAA ATTTCGTTTG GGAATACAAT GTCTTGGCGC AAATGTCCGC


 


1551
CCACGAAGAA ACCGGCGTTC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TCGCCGCCAA AAACTTCCAA CGCGGAATGT TCCTCGTCCG CCAAATGGAG


 


1651
TTCGCCCTCT TTGATATGAT GATTTACAGC GAAGACGACG AAGGCCGTCT


 


1701
GAAAAACTGG CAACAGGTTT TAGACAGCGT GCGCAAAGAA GTCGCCGTCG


 


1751
TCCGACCGCC CGAATACAAC CGCTTCGCCA ACAGCTTCGG CCACATCTTC


 


1801
GCAGGCGGCT ATTCCGCAGG CTATTACAGC TACGCGTGGG CGGAAGTATT


 


1851
GAGCGCGGAC GCATACGCCG CCTTTGAAGA AAGCGACGAT GTCGCCGCCA


 


1901
CAGGCAAACG CTTTTGGCAG GAAATCCTCG CCGTCGGCGG ATCGCGCAGC


 


1951
GCGGCAGAAT CCTTCAAAGC CTTCCGCGGA CGCGAACCGA GCATAGACGC


 


2001
ACTCTTGCGC CACAGCGGCT TCGACAACGC GGCTTGA






This corresponds to the amino acid sequence <SEQ ID 486; ORF 128.a>:










a128.pep




1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA



 


51
NTVEPLTGIT ERVGRIWGVV SHLNSVTDTP ELRAAYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSHAQKTKL NHDLRDFVLS GAELPPEQQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYADNRK LREQIYRAYV TRASELSDDG


 


251
KFDNTANIDR TLENALQTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR ESLGLADLQP WDLGYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLNGLFAQIK KLYGIGFTEK TVPVWHKDVR YFELQQNGET


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFS DGTLQLPTAY LVCNFTPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGVPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS EDDEGRLKNW QQVLDSVRKE VAVVRPPEYN RFANSFGHIF


 


601
AGGYSAGYYS YAWAEVLSAD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR HSGFDNAA*






m128/a128 66.0% identity in 677 aa overlap








The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 487>:









g128-1.seq (partial)










1
ATGATTGACA ACGCACTGCT CCACTTGGGC GAAGAACCCC GTTTTAATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCGT CCAAACCGCC ATCGCCGAAG


 


101
CGCGCGGACA AATCGCCGCC GTCAAAGCGC AAACGCACAC CGGCTGGGCG


 


151
AACACCGTCG AGCGTCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTCGTG TCCCATCTCA ACTCCGTCGT CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCTGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAACTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTTGCA ACGCTTTCCC CCGCACAAAA AACCAAGCTC GATCACGACC


 


401
TGCGCGATTT CGTATTGAGC GGCGCGGAAC TGCCGCCCGA ACGGCAGGCA


 


451
GAACTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCC


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGTTAC AAAATCGGCT TGCAGATTCC


 


651
GCACTACCTT GCCGTTATCC AATACGCCGG CAACCGCGAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGTGCCA GCGAACTTTC AAACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCATTGAA


 


801
AACCGCCAAA CTGCTCGGCT TTAAAAATTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACGCCC GAACAGGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAACACCTCG GTCTCGCCGA CCCGCAGCCG TGGGACTTGA


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTTCTGGCAG GCCTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT CGCCGAAAAA ACCGTTCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCAAAACC


 


1201
ATCGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGCTTTGCC GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCGCCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CGCGTTTAAG CCACGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AACCGGCCAC GGACTGCACC ACCTGCTTAC CCAAGTGGAC GAACTGGGCG


 


1451
TGTCCGGCAT CAACGGCGTA AAA






This corresponds to the amino acid sequence <SEQ ID 488; ORF 128-1.ng>:









g128-1.pep (partial)










1
MIDNALLHLG EEPRFNQIKT EDIKPAVQTA IAEARGQIAA VKAQTHTGWA



 


51
NTVERLTGIT ERVGRIWGVV SHLNSVVDTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFA TLSPAQKTKL DHDLRDFVLS GAELPPERQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYAGNRE LREQIYRAYV TRASELSNDG


 


251
KFDNTANIDR TLENALKTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR EHLGLADPQP WDLSYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLAGLFAQIK KLYGIGFAEK TVPVWHKDVR YFELQQNGKT


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFA DGTLQLPTAY LVCNFAPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV K






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 489>:










m128-1.seq




1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATCGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTCCGTCGC CGACACGCCC GAACTGCGCG


 


251
CCGTCTATAA CGAACTGATG CCCGAAATCA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAATTCCCC


 


351
CGAATTCGAC ACCCTCTCCC CCGCACAAAA AACCAAACTC AACCACGATC


 


401
TGCGCGATTT CGTCCTCAGC GGCGCGGAAC TGCCGCCCGA ACAGCAGGCA


 


451
GAACTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCC


 


601
GCCGCGCAAA GCGAAAGCAA AACAGGCTAC AAAATCGGCT TGCAGATTCC


 


651
ACACTACCTC GCCGTCATCC AATACGCCGA CAACCGCGAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGCGCCA GCGAACTTTC AGACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGCAA ACGCCCTGCA


 


801
AACCGCCAAA CTGCTCGGCT TCAAAAACTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACGCCC GAACAAGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAAAGCCTGA ACCTCGCCGA TTTGCAACCG TGGGACTTGG


 


1001
GCTACGCCAG CGAAAAACTG CGCGAAGCCA AATACGCGTT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTATTAAACG GACTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT TACCGAAAAA ACCGTCCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCGAAACC


 


1201
ATAGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGTTTTTCA GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCGCCCC ACCCGTCGGC


 


1351
GGCAGGGAAG CCCGCCTGAG CCACGACGAA ATCCTCATCC TCTTCCACGA


 


1401
AACCGGACAC GGGCTGCACC ACCTGCTTAC CCAAGTGGAC GAACTGGGCG


 


1451
TATCCGGCAT CAACGGCGTA GAATGGGACG CGGTCGAACT GCCCAGCCAG


 


1501
TTTATGGAAA ATTTCGTTTG GGAATACAAT GTCTTGGCAC AAATGTCAGC


 


1551
CCACGAAGAA ACCGGCGTTC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TCGCCGCCAA AAACTTCCAA CGCGGCATGT TCCTCGTCCG GCAAATGGAG


 


1651
TTCGCCCTCT TTGATATGAT GATTTACAGC GAAGACGACG AAGGCCGTCT


 


1701
GAAAAACTGG CAACAGGTTT TAGACAGCGT GCGCAAAAAA GTCGCCGTCA


 


1751
TCCAGCCGCC CGAATACAAC CGCTTCGCCT TGAGCTTCGG CCACATCTTC


 


1801
GCAGGCGGCT ATTCCGCAGG CTATTACAGC TACGCGTGGG CGGAAGTATT


 


1851
GAGCGCGGAC GCATACGCCG CCTTTGAAGA AAGCGACGAT GTCGCCGCCA


 


1901
CAGGCAAACG CTTTTGGCAG GAAATCCTCG CCGTCGGCGG ATCGCGCAGC


 


1951
GCGGCAGAAT CCTTCAAAGC CTTCCGCGGC CGCGAACCGA GCATAGACGC


 


2001
ACTCTTGCGC CACAGCGGTT TCGACAACGC GGTCTGA






This corresponds to the amino acid sequence <SEQ ID 490; ORF 128-1>:










m128-1.pep.




1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA



 


51
NTVEPLTGIT ERVGRIWGVV SHLNSVADTP ELRAVYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSPAQKTKL NHDLRDFVLS GAELPPEQQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSESKTGY KIGLQIPHYL AVIQYADNRE LREQIYRAYV TRASELSDDG


 


251
KFDNTANIDR TLANALQTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR ESLNLADLQP WDLGYASEKL REAKYAFSET


 


351
EVKKYFPVGK VLNGLFAQIK KLYGIGFTEK TVPVWHKDVR YFELQQNGET


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFS DGTLQLPTAY LVCNFAPPVG


 


451
GREARLSHDE ILILFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGVPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS EDDEGRLKNW QQVLDSVRKK VAVIQPPEYN RFALSFGHIF


 


601
AGGYSAGYYS YAWAEVLSAD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR HSGFDNAV*






m128-1/g128-1 94.5% identity in 491 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 491>:










a128-1.seq




1
ATGACTGACA ACGCACTGCT CCATTTGGGC GAAGAACCCC GTTTTGATCA



 


51
AATCAAAACC GAAGACATCA AACCCGCCCT GCAAACCGCC ATTGCCGAAG


 


101
CGCGCGAACA AATCGCCGCC ATCAAAGCCC AAACGCACAC CGGCTGGGCA


 


151
AACACTGTCG AACCCCTGAC CGGCATCACC GAACGCGTCG GCAGGATTTG


 


201
GGGCGTGGTG TCGCACCTCA ACTCCGTCAC CGACACGCCC GAACTGCGCG


 


251
CCGCCTACAA TGAATTAATG CCCGAAATTA CCGTCTTCTT CACCGAAATC


 


301
GGACAAGACA TCGAGCTGTA CAACCGCTTC AAAACCATCA AAAACTCCCC


 


351
CGAGTTCGAC ACCCTCTCCC ACGCGCAAAA AACCAAACTC AACCACGATC


 


401
TGCGCGATTT CGTCCTCAGC GGCGCGGAAC TGCCGCCCGA ACAGCAGGCA


 


451
GAATTGGCAA AACTGCAAAC CGAAGGCGCG CAACTTTCCG CCAAATTCTC


 


501
CCAAAACGTC CTAGACGCGA CCGACGCGTT CGGCATTTAC TTTGACGATG


 


551
CCGCACCGCT TGCCGGCATT CCCGAAGACG CGCTCGCCAT GTTTGCCGCT


 


601
GCCGCGCAAA GCGAAGGCAA AACAGGCTAC AAAATCGGTT TGCAGATTCC


 


651
GCACTACCTC GCCGTCATCC AATACGCCGA CAACCGCAAA CTGCGCGAAC


 


701
AAATCTACCG CGCCTACGTT ACCCGCGCCA GCGAGCTTTC AGACGACGGC


 


751
AAATTCGACA ACACCGCCAA CATCGACCGC ACGCTCGAAA ACGCCCTGCA


 


801
AACCGCCAAA CTGCTCGGCT TCAAAAACTA CGCCGAATTG TCGCTGGCAA


 


851
CCAAAATGGC GGACACCCCC GAACAAGTTT TAAACTTCCT GCACGACCTC


 


901
GCCCGCCGCG CCAAACCCTA CGCCGAAAAA GACCTCGCCG AAGTCAAAGC


 


951
CTTCGCCCGC GAAAGCCTCG GCCTCGCCGA TTTGCAACCG TGGGACTTGG


 


1001
GCTACGCCGG CGAAAAACTG CGCGAAGCCA AATACGCATT CAGCGAAACC


 


1051
GAAGTCAAAA AATACTTCCC CGTCGGCAAA GTATTAAACG GACTGTTCGC


 


1101
CCAAATCAAA AAACTCTACG GCATCGGATT TACCGAAAAA ACCGTCCCCG


 


1151
TCTGGCACAA AGACGTGCGC TATTTTGAAT TGCAACAAAA CGGCGAAACC


 


1201
ATAGGCGGCG TTTATATGGA TTTGTACGCA CGCGAAGGCA AACGCGGCGG


 


1251
CGCGTGGATG AACGACTACA AAGGCCGCCG CCGTTTTTCA GACGGCACGC


 


1301
TGCAACTGCC CACCGCCTAC CTCGTCTGCA ACTTCACCCC GCCCGTCGGC


 


1351
GGCAAAGAAG CCCGCTTGAG CCATGACGAA ATCCTCACCC TCTTCCACGA


 


1401
AACCGGACAC GGCCTGCACC ACCTGCTTAC CCAAGTCGAC GAACTGGGCG


 


1451
TATCCGGCAT CAACGGCGTA GAATGGGACG CAGTCGAACT GCCCAGTCAG


 


1501
TTTATGGAAA ATTTCGTTTG GGAATACAAT GTCTTGGCGC AAATGTCCGC


 


1551
CCACGAAGAA ACCGGCGTTC CCCTGCCGAA AGAACTCTTC GACAAAATGC


 


1601
TCGCCGCCAA AAACTTCCAA CGCGGAATGT TCCTCGTCCG CCAAATGGAG


 


1651
TTCGCCCTCT TTGATATGAT GATTTACAGC GAAGACGACG AAGGCCGTCT


 


1701
GAAAAACTGG CAACAGGTTT TAGACAGCGT GCGCAAAGAA GTCGCCGTCG


 


1751
TCCGACCGCC CGAATACAAC CGCTTCGCCA ACAGCTTCGG CCACATCTTC


 


1801
GCAGGCGGCT ATTCCGCAGG CTATTACAGC TACGCGTGGG CGGAAGTATT


 


1851
GAGCGCGGAC GCATACGCCG CCTTTGAAGA AAGCGACGAT GTCGCCGCCA


 


1901
CAGGCAAACG CTTTTGGCAG GAAATCCTCG CCGTCGGCGG ATCGCGCAGC


 


1951
GCGGCAGAAT CCTTCAAAGC CTTCCGCGGA CGCGAACCGA GCATAGACGC


 


2001
ACTCTTGCGC CACAGCGGCT TCGACAACGC GGCTTGA






This corresponds to the amino acid sequence <SEQ ID 492; ORF 128-1.a>:










a128-1.pep











1
MTDNALLHLG EEPRFDQIKT EDIKPALQTA IAEAREQIAA IKAQTHTGWA



 


51
NTVEPLTGIT ERVGRIWGVV SHLNSVTDTP ELRAAYNELM PEITVFFTEI


 


101
GQDIELYNRF KTIKNSPEFD TLSHAQKTKL NHDLRDFVLS GAELPPEQQA


 


151
ELAKLQTEGA QLSAKFSQNV LDATDAFGIY FDDAAPLAGI PEDALAMFAA


 


201
AAQSEGKTGY KIGLQIPHYL AVIQYADNRK LREQIYRAYV TRASELSDDG


 


251
KFDNTANIDR TLENALQTAK LLGFKNYAEL SLATKMADTP EQVLNFLHDL


 


301
ARRAKPYAEK DLAEVKAFAR ESLGLADLQP WDLGYAGEKL REAKYAFSET


 


351
EVKKYFPVGK VLNGLFAQIK KLYGIGFTEK TVPVWHKDVR YFELQQNGET


 


401
IGGVYMDLYA REGKRGGAWM NDYKGRRRFS DGTLQLPTAY LVCNFTPPVG


 


451
GKEARLSHDE ILTLFHETGH GLHHLLTQVD ELGVSGINGV EWDAVELPSQ


 


501
FMENFVWEYN VLAQMSAHEE TGVPLPKELF DKMLAAKNFQ RGMFLVRQME


 


551
FALFDMMIYS EDDEGRLKNW QQVLDSVRKE VAVVRPPEYN RFANSFGHIF


 


601
AGGYSAGYYS YAWAEVLSAD AYAAFEESDD VAATGKRFWQ EILAVGGSRS


 


651
AAESFKAFRG REPSIDALLR HSGFDNAA*






m128-1/a128-1 97.8% identity in 677 aa overlap








a128-1/P44573









sp|P44573|OPDA_HAEIN OLIGOPEPTIDASE A >gi|1075082|pir||O64055



oligopeptidase A (prlC) homolog - Haemophilus influenzae (strain Rd KW20)


>gi|1573174 (U32706) oligopeptidase A (prlC) [Haemophilus influenzae Rd]


Length = 681 Score = 591 bits (1507), Expect = e−168


Identities = 309/677 (45%), Positives = 415/677 (60%), Gaps = 4/677 (0%)











Query:
4
NALLHLGEEPRFDQIKTEDIKPALQTXXXXXXXXXXXXXXXTHTGWANTVEPLTGITERV
63





N LL++   P F QIK E I+PA++                 H  W N + PLT   +R+



Sbjct:
5
NPLLNIQGLPPFSQIKPEHIRPAVEKLIQDCRNTIEQVLKQPHFTWENFILPLTETNDRL
64


 


Query:
64
GRIWGVVSHLNSVTDTPELRAAYNELMPEITVFFTEIGQDIELYNRFKTIKNSPEFDTLS
123




 R W  VSHLNSV ++ ELR AY   +P ++ + T +GQ   LYN +  +KNS EF   S



Sbjct:
65
NRAWSPVSHLNSVKNSTELREAYQTCLPLLSEYSTWVGQHKGLYNAYLALKNSAEFADYS
124


 


Query:
124
HAQKTKLNHDLRDFVLSGAELPPEQQAELAKLQTEGAQLSAKFSQNVLDATDAFGIYFDD
183




 AQK  + + LRDF LSG  L  E+Q    ++    ++L+++FS NVLDAT  +    ++



Sbjct:
125
IAQKKAIENSLRDFELSGIGLSEEKQQRYGEIVARLSELNSQFSNNVLDATMGWEKLIEN
184


 


Query:
184
AAPLAGIPEDALAMFAAAAQSEGKTGYKIGLQIPHYLAVIQYADNRKLREQTYRAYVTRA
243




 A LAG+PE AL     +A+S+G  GY+  L+IP YL V+ Y +NR LRE++YRAY TRA



Sbjct:
185
EAELAGLPESALQAAQQSAESKGLKGYRFTLEIPSYLPVMTYCENRALREEMYRAYATRA
244


 


Query:
244
SELSDD-GKFDNTANIDRTLENALQTAKLLGFKNYAELSLATKMADTPEQVLNFLHDLAR
302




SE   + GK+DN+  ++  L   ++ AKLLGF  Y ELSLATKMA+ P+QVL+FL  LA



Sbjct:
245
SEQGPNAGKWDNSKVMEEILTLRVELAKLLGFNTYTELSLATKMAENPQQVLDFLDHLAE
304


 


Query:
303
RAKPYAEKDLAEVKAFARESLGLADLQPWDLGYAGEKLREAKYAFSETEVKKYFPVGKVL
362




RAKP  EK+L E+K +  +  G+ +L PWD+G+  EK ++  YA ++ E++ YFP  +V+



Sbjct:
305
RAKPQGEKELQELKGYCEKEFGVTELAPWDIGFYSEKQKQHLYAINDEELRPYFPENRVI
364


 


Query:
363
NGLFAQIKKLYGIGFTE-KTVPVWHKDVRYFEL-QQNGETIGGVYMDLYAREGKRGGAWM
420




+GLF  IK+++ I   E K V  WHKDVR+F+L  +N +  G  Y+DLYARE KRGGAWM



Sbjct:
365
SGLFELIKRIFNIRAVERKGVDTWHKDVRFFDLIDENDQLRGSFYLDLYAREHKRGGAWM
424


 


Query:
421
NDYKGRRRFSDGTLQLPTAYLVCNFTPPVGGKEARLSHDEIXXXXXXXXXXXXXXXXQVD
480




+D  GR+R  DG+++ P AYL CNF  P+G K A  +H+E+                Q+D



Sbjct:
425
DDCIGRKRKLDGSIETPVAYLTCNFNAPIGNKPALFTHNEVTTLFHEFGHGIHHMLTQID
484


 


Query:
481
ELGVSGINGVEWDAVELPSQFMENFVWEYNVLAQMSAHEETGVPLPKELFDKMLAAKNFQ
540




   V+GINGV WDAVELPSQFMEN+ WE   LA +S H ETG PLPKE   ++L AKNFQ



Sbjct:
485
VSDVAGINGVPWDAVELPSQFMENWCWEEEALAFISGHYETGEPLPKEKLTQLLKAKNFQ
544


 


Query:
541
RGMFLVRQMEFALFDMMIYSEDDEGRLKNWQQVLDSVRKEVAVVRPPEYNRFANSFGHIF
600




  MF++RQ+EF +FD  ++   D  +       L SV+ +VAV++  ++ R  +SF HIF



Sbjct:
545
AAMFILRQLEFGIFDFRLHHTFDAEKTNQILDTLKSVKSQVAVIKGVDWARAPHSFSHIF
604


 


Query:
601
XXXXXXXXXXXXWAEVLSADAYAAFEESDDV-AATGKRFWQEILAVGGSRSAAESFKAFR
659




            WAEVLSADAY+ FEE       TGK F  EIL  GGS    E FK FR



Sbjct:
605
AGGYAAGYYSYLWAEVLSADAYSRFEEEGIFNPITGKSFLDEILTRGGSEEPMELFKRFR
664


 


Query:
660
GREPSIDALLRHSGFDN
676




GREP +DALLRH G  N



Sbjct:
665
GREPQLDALLRHKGIMN
681






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 493>:










g129.seq




1
ATGCTTTCAC CTCCTCGGCG TAAAACGGCG GCACATCAAT CAAGCCGTCT



 


51
TTCATTTGCG TGCGGAAAAA ATGCGGCGTG TTGCCGTGAT CAAAATCAAT


 


101
ATCGTGCAGC ATCCAGCCCA AATCGCGGTT TGCCTCGCTT TCCGATAACG


 


151
CCGACGGCGG CAGCGGTTCA CCCTTATCCG CGCTTTCGCC ATTTGCCCTT


 


201
TCAGGCTGCG GGCATAGGGG CGGAACAGGC GGCGGTCGAA TCCTGTTTCA


 


251
TCCGGACAAA CGCGTTGGCA GTCGGAAAAT CCGGCCGGCC GTGTCAAATA


 


301
ATGCGTTACT TTGGCCGGGT CTTGTCCTTT GTAAGCGGCG GTCTTTTTTT


 


351
GCGCGCCATC CGCATCTGTT TGGGCGCATG GCAAACGGCG GCTGCCGTAC


 


401
AATCAAAATG TTTGGCGATT TCATGCAGAC AGGCATCCGG ATGCCGCCCG


 


451
ACATATCGAG CCGGTTTTTG CCTATCCGAT TTGGCGGCAT TTAGGCCGGT


 


501
AACTTGA






This corresponds to the amino acid sequence <SEQ ID 494; ORF 129.ng>:










g129.pep




1
MLSPPRRKTA AHQSSRLSFA CGKNAACCRD QNQYRAASSP NRGLPRFPIT



 


51
PTAAAVHPYP RFRHLPFQAA GIGAEQAAVE SCFIRTNALA VGKSGRPCQI


 


101
MRYFGRVLSF VSGGLFLRAI RICLGAWQTA AAVQSKCLAI SCRQASGCRP


 


151
TYRAGFCLSD LAAFRPVT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 495>:









m129.seq (partial)










1
..TATCTGCGCT TTCACTATTT GCCCTTTCAG GCTGCGGGCA TAGGGACGGA



 


51
  ACAGGTAGCG GTCAAATCCT GTTTCATCCA AATAAACACG TTGGTAGTCG


 


101
  GAAAATTCGG CCGGCTGTGT CAAATAATGC GTTACTTTGG CCGGGTCTTG


 


151
  TTCTTTGTAA GTGGTGGTCT TTTTTTGCGC GTTATCCCCA TCTGTTTGAG


 


201
  TGCATAGCAA ATGGTGGCTG CCGTACAATC AAAATGTTTG GCGATTTCAT


 


251
  GCAGATAGGC ATCCGGGTGT TGCCCAACAT ATTGAGCCGG TTTTTGCCTA


 


301
  TCCGATTTGA CGGCATTTAG ACCGGTAACT TGA






This corresponds to the amino acid sequence <SEQ ID 496; ORF 129>:









m129.pep (partial)










1
..YLRFHYLPFQ AAGIGTEQVA VKSCFIQINT LVVGKFGRLC QIMRYFGRVL



 


51
  FFVSGGLFLR VIPICLSAXQ MVAAVQSKCL AISCRXASGC CPTYXAGFCL


 


101
  SDLTAFRPVT *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 129 shows 79.1% identity over a 110 aa overlap with a predicted ORF (ORF 129.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 497>:









a129.seq (partial)










1
TATCTGCGCT TTCACTATTT GCCCTTTCAG GCTGCGGGCA TAGGGACGGA



 


51
ACAGGTAGCG GTCAAATCCT GTTTCATCCA AATAAACACG TTGGTAGTCG


 


101
GAAAATTCGG CCAGCTGTGT CAAATAATGC GTTACTTTGG CCGGGTCTTG


 


151
TTCTTTGTAA GTGGTGGTCT TTTTTTGCGC GTTATCCCCA TCTGTTTGAG


 


201
TGCATAGCAA ATGGTGGCTG CCGTACAATC AAAATGTTTG GCGATTTCAT


 


251
GCAGATAGGC ATCCTGGTGT TGCCCAACAT ATTGAGCCGG TTTTTGCCTA


 


301
TCCGATTTGA CGGCATTTAG ACCGGTAACT TGA






This corresponds to the amino acid sequence <SEQ ID 498; ORF 129.a>:









a129.pep (partial)










1
YLRFHYLPFQ AAGIGTEQVA VKSCFIQINT LVVGKFGQLC QIMRYFGRVL



 


51
FFVSGGLFLR VIPICLSA*Q MVAAVQSKCL AISCR*ASWC CPTY*AGFCL


 


101
SDLTAFRPVT *






m129/a129 98.2% identity in 110 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 499>:










g130.seq




1
ATGAAACAAC TCCGCGACAA CAAAGCCCAA GGCTCTGCAC TGTTTACCCT


 


51
TGTGAGCGGT ATCGTTATTG TTATTGCAGT CCTTTATTTC CTGATTAAGC


 


101
TGGCGGGCAG TGGATCGTTC GGCGATGTCG ATGCCACTAC GGAAGCGGCA


 


151
ACGCAGACCC GCATCCAGCC TGTCGGACAA TTGACGATGG GTGACGGCAT


 


201
CCCCGTCGGC GAACGCCAAG GCGAACAGAT TTTCGGCAAA ATCTGTATCC


 


251
AATGCCACGC GGCGGACAGC AATGTGCCGA ACGCTCCGAA ACTGGAACAC


 


301
AACGGCGACT GGGCGCCGCG TATCGCGCAA GGCTTCGATA CCTTGTTCCA


 


351
ACACGCGCTG AACGGCTTTA ACGCCATGCC TGCCAAAGGC GGTGCGGCAG


 


401
ACCTGACCGA TCAGGAACTC AAACGGGCGA TTACCTACAT GGCGAATAAA


 


451
AGCGGCGGTT CTTTCCCGAA TCCTGATGAG GCTGCGCCTG CCGACAATGC


 


501
CGCTTCAGGA ACAGCTTCTG CTCCTGCCGA TAGTGCAGCT CCGGCAGAAG


 


551
CGAAGGCAGA AGACAAGGGT GCGGCAGCCC CTGCGGTCGG CGTTGACGGT


 


601
AAAAAAGTCT TCGAAGCAAC CTGTCAGGTG TGCCACGGCG GTTCGATTCC


 


651
CGGTATTCCC GGCATAGGCA AAAAAGACGA TTGGGCACCG CGTATCAAAA


 


701
AAGGCAAAGA AACCTTGCAC AAACATGCCC TTGAAGGCTT TAACGCGATG


 


751
CCGGCCAAAG GCGGCAATGC AGGTTTGAGC GATGACGAAG TCAAAGCGGC


 


801
TGTTGACTAT ATGGCAAACC AATCCGGTGC AAAATTCTAA






This corresponds to the amino acid sequence <SEQ ID 500; ORF 130.ng>:










g130.pep




1
MKQLRDNKAQ GSALFTLVSG IVIVIAVLYF LIKLAGSGSF GDVDATTEAA


 


51
TQTRIQPVGQ LTMGDGIPVG ERQGEQIFGK ICIQCHAADS NVPNAPKLEH


 


101
NGDWAPRIAQ GFDTLFQHAL NGFNAMPAKG GAADLTDQEL KRAITYMANK


 


151
SGGSFPNPDE AAPADNAASG TASAPADSAA PAEAKAEDKG AAAPAVGVDG


 


201
KKVFEATCQV CHGGSIPGIP GIGKKDDWAP RIKKGKETLH KHALEGFNAM


 


251
PAKGGNAGLS DDEVKAAVDY MANQSGAKF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 501>:









m130.seq (partial)










1
..GGCGAACAGA TTTTCGGCAA AATCTGTATC CAATGCCACG CGGCGGACAG



 


51
  CAATGTGCCG AACGCTCCGA AACTGGAACA CAACGGCGAT TrGGCACCGC


 


101
  GTATCGgCAA GGCTTCGATA CCTTGTTCCA ACACGCGCTG AACGGCTTTA


 


151
  ACGCCATGCC TGCAAAAGGC GGTGCGGCAG ACCTGACCGA TCAGGAACTT


 


201
  AAACGGGCGA TTACTTACAT GGCGAACAAA AGCGGCGGTT CTTTCCCGAA


 


251
  TCCTGATGAG GCTGCGCCTG CCGACAATGC CGCTTCAGGA ACAGCTTCTG


 


301
  CTCCTGCCGA TAGTGCAGCT CCGGCAGAAG CGAAGGCAGA AGACAAGGGT


 


351
  GCGGCAcCCC TGCGGTCGGC GTTGACGGTA AAAAAGTCTT CGAAGCAACC


 


401
  TGTCAGGTGT GCCACGGCGG TTCGATTCCC GGTATTCCCG GCATAGGCAA


 


451
  AAAAGACGAT TGGGCACCGC GTATCAAAAA AGGCAAAGAA ACCTTGCACA


 


501
  AACACGCCCT TGAAGGCTTT AACGCGATGC CTGCCAAArG CGgCAATGCA


 


551
  GGTTTGAGCG ATGACGAAgT CAAAGCGGCT GTTGACTATA TGGCAAACCA


 


601
  ATCCGGTGCA AAATTCTAA






This corresponds to the amino acid sequence <SEQ ID 502; ORF 130>:









m130.pep (partial)










1
..GEQIFGKICI QCHAADSNVP NAPKLEHNGD XAPRIQGFDT LFQHALNGFN



 


51
  AMPAKGGAAD LTDQELKRAI TYMANKSGGS FPNPDEAAPA DNAASGTASA


 


101
  PADSAAPAEA KAEDKGAAPA VGVDGKKVFE ATCQVCHGGS IPGIPGIGKK


 


151
  DDWAPRIKKG KETLHKHALE GFNAMPAKXG NAGLSDDEVK AAVDYMANQS


 


201
  GAKF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 130 shows 98.1% identity over a 206 aa overlap with a predicted ORF (ORF 130.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 503>:










a130.seq




1
ATGAAACAAC TCCGCGACAA CAAAGCCCAA GGCTCTGCAC TGTTTACCCT


 


51
TGTGAGCGGT ATCGTTATTG TTATTGCAGT CCTTTATTTC CTGATTAAGC


 


101
TGGCGGGCAG CGGCTCGTTC GGCGATGTCG ATGCCACTAC GGAAGCAGCA


 


151
ACGCAGACCC GTATCCAGCC TGTCGGACAA TTGACGATGG GCGACGGCAT


 


201
CCCCGTCGGC GAACGCCAAG GCGAACAGAT TTTCGGCAAA ATCTGTATCC


 


251
AATGCCACGC GGCGGACAGC AATGTGCCGA ACGCTCCGAA ACTGGAACAC


 


301
AACGGCGATT GGGCGCCGCG TATCGCGCAA GGCTTCGATA CCTTGTTCCA


 


351
ACACGCGCTG AACGGCTTTA ACGCCATGCC TGCCAAAGGC GGTGCGGTAG


 


401
ACCTGACCGA TCAGGAACTC AAACGGGCGA TTACTTACAT GGCGAACAAA


 


451
AGCGGCGGTT CTTTCCCGAA TCCTGATGAG GCTGCGCCTG CCGACAATGC


 


501
CGCTTCAGGA ACAGCTTCTG CTCCTGCCGA TAGTGCAGCT CCGGCAGAAG


 


551
CGAAGGCAGA AGACAAGGGT GCGGCAGCCC CTGCGGTCGG CGTTGACGGT


 


601
AAAAAAGTCT TCGAAGCAAC CTGTCAGGTG TGCCACGGCG GTTCGATTCC


 


651
CGGTATTCCC GGCATAGGCA AAAAAGACGA TTGGGCACCG CGTATCAAAA


 


701
AAGGCAAAGA AACCTTGCAC AAACACGCCC TTGAAGGCTT TAACGCGATG


 


751
CCTGCCAAAG GCGGCAATGC AGGTTTGAGC GATGACGAAG TCAAAGCGGC


 


801
TGTTGACTAT ATGGCAAACC AATCCGGTGC AAAATTCTAA






This corresponds to the amino acid sequence <SEQ ID 504; ORF 130.a>:










a130.pep




1
MKQLRDNKAQ GSALFTLVSG IVIVIAVLYF LIKLAGSGSF GDVDATTEAA


 


51
TQTRIQPVGQ LTMGDGIPVG ERQGEQIFGK ICIQCHAADS NVPNAPKLEH


 


101
NGDWAPRIAQ GFDTLFQHAL NGFNAMPAKG GAVDLTDQEL KRAITYMANK


 


151
SGGSFPNPDE AAPADNAASG TASAPADSAA PAEAKAEDKG AAAPAVGVDG


 


201
KKVFEATCQV CHGGSIPGIP GIGKKDDWAP RIKKGKETLH KHALEGFNAM


 


251
PAKGGNAGLS DDEVKAAVDY MANQSGAKF*






m130/a130 97.6% identity in 206 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 505>:










g132.seq




1
ATGGAAGCCT TCAAAACCCT AATTTGGATT ATTAATATTA TTTCCGCTTT


 


51
GGCCGTCATC GTGTTAGTAT TGCTCCAACA CGGCAAAGGC GCGGATGCCG


 


101
GCGCGACCTT CGGATCGGGA AGCGGCAGCG CGCAAGGCGT ATTCGGCTCT


 


151
GCCGGCAACG CCAACTTcct CAgccGCTCG AccGccGTTG CAGCAACAtt


 


201
tttcttTGca acctgcAtgg gctatggTgt atattcacac CCACACGACA


 


251
AAACACGGTT TGGACTtcag caacataCGA CAGACTCAGC AagcACCCAA


 


301
ACCcgtAAGC AATACCGAAC CTTCTGCCCC TGTTCCTCAG CAGCAGAAAT


 


351
AACagtTTTT CAAATgccga caTGgtga






This corresponds to the amino acid sequence <SEQ ID 506; ORF 132.ng>:










g132.pep




1
MEAFKTLIWI INIISALAVI VLVLLQHGKG ADAGATFGSG SGSAQGVFGS


 


51
AGNANFLSRS TAVAATFFFA TCMGYGVYSH PHDKTRFGLQ QHTTDSASTQ


 


101
TRKQYRTFCP CSSAAEITVF QMPTW*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 507>:









m132.seq (partial)










1
ATGGAACCCT TCAAAACCTT AATTTGGATT GTTAATTTAA TTTCCGCTTT



 


51
GGCCGTCTTC GTGTTAGTAT TGCTCCAACA CGGCAAAGGC GCGGATGCCG


 


101
GCGCGACTTT CGGA...






This corresponds to the amino acid sequence <SEQ ID 508; ORF 132>:








m132.pep (partial)








1
MEPFKTLIWI VNLISALAVF VLVLLQHGKG ADAGATFG...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 132 shows 89.5% identity over a 38 aa overlap with a predicted ORF (ORF 132.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 509>:










a132.seq




1
ATGGAAGCCT TCAAAACCCT AATTTGGATT GTTAATATAA TTTCCGCTTT


 


51
GGCCGTCATC GTGTTAGTAT TGCTCCAACA CGGCAAAGGC GCGGATGCCG


 


101
GCGCGACTTT CGGATCGGGA AGCGGCAGCG CGCAAGGCGT ATTCGGCTCT


 


151
GCCGGCAACG CTAACTTCCT CAGCCGCTCG ACCGCCGTTG CAGCAACATT


 


201
TTTCTTTGCA ACCTGCATGg GCTATGGTGT ATATTCACAC CCACACGACA


 


251
AAACACGGTT TGGACTTCAG CAACGTACAA CAAACTCAGC AAGCACCCAA


 


301
ACCCGTAAGC AATACCGAAC CTTCTGCCCC TGTTCCTCAG CAGCAGAAAT


 


351
AACAGTTTTT CAAATGCCGA CATGGTGA






This corresponds to the amino acid sequence <SEQ ID 510; ORF 132.a>:










a132.pep




1
MEAFKTLIWI VNIISALAVI VLVLLQHGKG ADAGATFGSG SGSAQGVFGS


 


51
AGNANFLSRS TAVAATFFFA TCMGYGVYSH PHDKTRFGLQ QRTTNSASTQ


 


101
TRKQYRTFCP CSSAAEITVF QMPTW*






m132/a132 92.1% identity in 38 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 511>:










g134.seq




1
ATGTCCCAAG AAATCCTCGA CCAAGTGCGC CGCCGCCGCA CGTTTGCCAT


 


51
CATCTCCCAC CCCGATGCGG GTAAAACCAC GCTGACCGAA AAACTGCTGC


 


101
TGTTTTCGGG CGCGATTCAA AGCGCAGGCA CGGTGAAAGG TAAGAAAACC


 


151
GGCAAATTCG CCACCTCCGA CTGGATGGAC ATCGAGAAGC AGCGCGGCAT


 


201
TTCCGTGGCA TCAAGCGTGA TGCAGTTCGA CTACAAAGAC CACACCGTCA


 


251
ACCTCTTGGA CACGCCGGGA CACCAAGACT TCTCCGAAGA CACCTACCGC


 


301
GTTTTAACCG CAGTGGACAG CGCCTTGATG GTCATCGACG CGGCAAAAGG


 


351
CGTGGAAGCG CAAACCATCA AACTCTTGAA CGTCTGCCGC CTGCGCGATA


 


401
CGCCGATTGT TACCTTCATG AACAAATACG ACCGCGAAGT GCGCGATTCT


 


451
TTGGAACTCT TGGACGAAGT GGAAGACATC CTGCAAATCC GCTGCGCGCC


 


501
CGTTACCTGG CCGATCGGTA TGGGCAAAAA CTTCAAGGGC GTGTACCACA


 


551
TCCTGAACGA CGAAATCTAT CTCTTTGAAG CGGGCGGCGA ACGCCTGCCG


 


601
CACGAGTTCG ACATCATCAA AGGCATAAAC AATCCCGAAT TGGAACAACG


 


651
CTTTCCGTTG GAAATCCAGC AGTTGCGCGA CGAAATCGAA TTGGTGCAGG


 


701
CGGCTTCCAA CGAATTTAAT CTCGacgaAT TTCTCGccgG CGAACTCACG


 


751
CCAGTGTTCT TCGGCTCTGC GATTAACAAC TTCGGCATTC AGGAAATCCT


 


801
CAATTCATTG ATTGACTGGG CACCCGCACC GAAACCGCGC GACGCGACCA


 


851
TGCGCATGGT CGGGCCGGAC GAGCCGAAAT TTTCCGGATT TATCTTTAAA


 


901
ATCCAAGCCA ATATGGACCC GAAACACCGC GACCGTATCG CCTTCTTGCG


 


951
CGTCTGCTCC GGTAAATTCG AGCGCGGCAT GAAGATGAAA CACCTGCGTA


 


1001
TCAACCGCGA AATCGCCGCC TCCAGCGTAG TAACCTTCAT GTCGCACGAC


 


1051
CGCGAACTGG CGGAAGAAGC CTACGCCGGC GACATCATCG GCATCCCGAA


 


1101
CCACGGCAAC ATCCAAATCG GCGACAGCTT CTCCGAAGGC GAACAACTGG


 


1151
CGTTTACCGG CATCCCATTC TTCGCGCCCG AACTGTTCCG CAGCGTCCGC


 


1201
ATCAAAAACC CGCTGAAAAT CAAACAACTG CAAAAAGGTT TGCAACAACT


 


1251
CGGCGAAGAA GGTGCGGTTC AAGTATTCAA ACCGATGAGC GGCGCGGATT


 


1301
TGATTTTGGG TGCGGTCGGC GTGTTGCAGT TTGAAGTCGT AACCTCACGC


 


1351
CTCGCCAACG AATACGGCGT GGAAGCCGTG TTCGACAGCG CATCCATCTG


 


1401
GTCGGCGCGC TGGGTATCGT GCGACGACAA GAAAAAACTG GCGGAATTTG


 


1451
AAAAAGCCAA CGCAGGCAAC CTCGCCATCG ACGCAGGCGG CAACCTCGCC


 


1501
TACCTCGCCC CCAACCGCGT GAATTTGGGG TTGACGCAAG AACGCTGGCC


 


1551
GGACATCGTG TTCCACGAAA CGCGCGAACA TTCGGTCAAA CTCTAA






This corresponds to the amino acid sequence <SEQ ID 512; ORF 134.ng>:










g134.pep




1
MSQEILDQVR RRRTFAIISH PDAGKTTLTE KLLLFSGAIQ SAGTVKGKKT


 


51
GKFATSDWMD IEKQRGISVA SSVMQFDYKD HTVNLLDTPG HQDFSEDTYR


 


101
VLTAVDSALM VIDAAKGVEA QTIKLLNVCR LRDTPIVTFM NKYDREVRDS


 


151
LELLDEVEDI LQIRCAPVTW PIGMGKNFKG VYHILNDEIY LFEAGGERLP


 


201
HEFDIIKGIN NPELEQRFPL EIQQLRDEIE LVQAASNEFN LDEFLAGELT


 


251
PVFFGSAINN FGIQEILNSL IDWAPAPKPR DATMRMVGPD EPKFSGFIFK


 


301
IQANMDPKHR DRIAFLRVCS GKFERGMKMK HLRINREIAA SSVVTFMSHD


 


351
RELAEEAYAG DIIGIPNHGN IQIGDSFSEG EQLAFTGIPF FAPELFRSVR


 


401
IKNPLKIKQL QKGLQQLGEE GAVQVFKPMS GADLILGAVG VLQFEVVTSR


 


451
LANEYGVEAV FDSASIWSAR WVSCDDKKKL AEFEKANAGN LAIDAGGNLA


 


501
YLAPNRVNLG LTQERWPDIV FHETREHSVK L*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 513>:










m134.seq




1
ATGTCCCAAG AAATCCTCGA CCAAGTGCGC CGCCGCCGCA CGTTTGCCAT


 


51
CATCTCCCAC CCTGACGCAG GTAAAACCAC GTTGACTGAA AAACTCTTGC


 


101
TGTTTTCGGG CGCGATTCAG AGCGCGGGTA CGGTAAAAGG CAAGAAAACC


 


151
GGCAAATTCG CCACTTCCGA CTGGATGGAA ATCGAGAAGC AGCGCGGCAT


 


201
TTCCGTGGCA TCAAGTGTGA TGCAGTTCGA TTACAAAGAC CACACCGTCA


 


251
ACCTCTTGGA CACGCCGGGA CACCAAGACT TCTCCGAAGA CACCTACCGC


 


301
GTTTTAACCG CCGTGGACAG CGCATTAATG GTCATCGACG CGGCAAAAGG


 


351
CGTGGAAGCG CAAACCATCA AGCTCTTAAA CGTCTGCCGC CTGCGCGATA


 


401
CACCGATTGT TACGTTTATG AACAAATACG ACCGCGAAGT GCGCGATTCC


 


451
CTGGAACTTT TGGACGAAGT GGAAAACATT TTAAAAATCC GCTGCGCGCC


 


501
CGTTACCTGG CCGATCGGTA TGGGCAAAAA CTTCAAGGGC GTGTACCACA


 


551
TCCTGAACGA TGAAATTTAT CTCTTTGAAG CTGGCGGCGA ACGCCTGCCG


 


601
CACGAGTTCG ACATCATCAA AGGCATCGAT AATCCTGAAT TGGAACAACG


 


651
CTTTCCGTTG GAAATCCAGC AGTTGCGCGA CGAAATCGAA TTGGTGCAGG


 


701
CGGCTTCCAA CGAGTTTAAT CTCGACGAAT TCCTCGCCGG CGAACTCACG


 


751
CCCGTATTCT TCGGCTCTGC GATTAACAAC TTCGGTATTC AGGAAATCCT


 


801
CAATTCATTG ATTGACTGGG CGCCCGCGCC GAAACCGCGC GACGCGACCG


 


851
TACGTATGGT CGAGCCGGAC GAGCCGAAGT TTTCCGGATT TATCTTCAAA


 


901
ATCCAAGCCA ATATGGACCC GAAACACCGC GACCGTATTG CCTTCTTGCG


 


951
CGTCTGCTCC GGCAAATTCG AGCGCGGCAT GAAGATGAAA CACCTGCGTA


 


1001
TCAACCGCGA AATCGCCGCC TCCAGCGTGG TTACCTTCAT GTCGCACGAC


 


1051
CGCGAGCTGG TTGAAGAAGC CTACGCCGGC GACATTATCG GCATCCCGAA


 


1101
CCACGGCAAC ATCCAAATCG GCGACAGCTT CTCCGAAGGC GAACAACTGG


 


1151
CGTTCACCGG CATCCCATTC TTCGCACCCG AACTGTTCCG CAGCGTACGC


 


1201
ATCAAAAACC CGCTGAAAAT CAAACAACTG CAAAAAGGCT TGCAACAGCT


 


1251
CGGCGAAGAA GGCGCGGTGC AGGTGTTCAA ACCGATGAGC GGCGCGGATT


 


1301
TGATTTTGGG CGCGGTCGGC GTGTTGCAGT TTGAAGTCGT TACCTCGCGC


 


1351
CTCGCCAACG AATACGGCGT AGAAGCCGTG TTCGACAGCG CATCCATCTG


 


1401
GTCGGCGCGC TGGGTATCGT GCGACGACAA GAAAAAACTG GCTGAATTTG


 


1451
AAAAAGCCAA CGCGGGCAAC CTCGCCATCG ACGCAGGCGG CAACCTCGCC


 


1501
TACCTCGCCC CCAACCGCGT GAATTTGGGA CTCACGCAAG AACGTTGGCC


 


1551
GGACATCGTG TTCCACGAAA CACGCGAACA TTCGGTCAAA CTGTAA






This corresponds to the amino acid sequence <SEQ ID 514; ORF 134>:










m134.pep




1
MSQEILDQVR RRRTFAIISH PDAGKTTLTE KLLLFSGAIQ SAGTVKGKKT


 


51
GKFATSDWME IEKQRGISVA SSVMQFDYKD HTVNLLDTPG HQDFSEDTYR


 


101
VLTAVDSALM VIDAAKGVEA QTIKLLNVCR LRDTPIVTFM NKYDREVRDS


 


151
LELLDEVENI LKIRCAPVTW PIGMGKNFKG VYHILNDEIY LFEAGGERLP


 


201
HEFDIIKGID NPELEQRFPL EIQQLRDEIE LVQAASNEFN LDEFLAGELT


 


251
PVFFGSAINN FGIQEILNSL IDWAPAPKPR DATVRMVEPD EPKFSGFIFK


 


301
IQANMDPKHR DRIAFLRVCS GKFERGMKMK HLRINREIAA SSVVTFMSHD


 


351
RELVEEAYAG DIIGIPNHGN IQIGDSFSEG EQLAFTGIPF FAPELFRSVR


 


401
IKNPLKIKQL QKGLQQLGEE GAVQVFKPMS GADLILGAVG VLQFEVVTSR


 


451
LANEYGVEAV FDSASIWSAR WVSCDDKKKL AEFEKANAGN LAIDAGGNLA


 


501
YLAPNRVNLG LTQERWPDIV FHETREHSVK L*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 134 shows 98.7% identity over a 531 aa overlap with a predicted ORF (ORF 134.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 515>:










a134.seq




1
ATGTCCCAAG AAATCCTCGA CCAAGTGCGC CGCCGCCGCA CGTTTGCCAT


 


51
CATCTCCCAC CCTGACGCAG GTAAAACCAC GTTGACTGAA AAACTCTTGC


 


101
TGTTTTCAGG TGCGATTCAA AGCGCGGGTA CGGTAAAAGG CAAGAAAACC


 


151
GGCAAATTCG CCACCTCCGA CTGGATGGAC ATCGAGAAGC AGCGCGGCAT


 


201
TTCCGTGGCA TCAAGCGTGA TGCAGTTCGA CTATAAAGAC CACACCGTCA


 


251
ACCTTTTGGA CACGCCGGGA CACCAAGACT TCTCCGAAGA CACCTACCGC


 


301
GTTTTGACCG CCGTCGATAG TGCCTTGATG GTCATCGACG CGGCAAAAGG


 


351
CGTGGAAGCG CAAACCATCA AACTCTTGAA CGTCTGCCGC CTGCGCAATA


 


401
CGCCGATTGT TACGTTCATG AACAAATACG ACCGCGAAGT GCGCGATTCC


 


451
CTGGAATTGC TGGACGAAGT GGAAAACATC CTGCAAATCC GCTGCGCGCC


 


501
CGTAACCTGG CCGATCGGCA TGGGCAAAAA CTTCAAAGGC GTGTACCACA


 


551
TCCTGAACGA CGAAATCTAT CTCTTTGAAG CGGGCGGCGA ACGCTTGCCG


 


601
CACGAGTTCG ACATCATCAA AGGCATCGAT AATCCCGAAT TGGAACAACG


 


651
CTTTCCGTTA GAAATACAGC AGTTGCGCGA CGAAATCGAA TTGGTGCAGG


 


701
CGGCTTCCAA CGAGTTCAAT CTCGACGAAT TCCTCGCCGG CGAACTCACG


 


751
CCCGTATTCT TCGGCTCTGC GATTAACAAC TTCGGTATTC AGGAAATCCT


 


801
CAATTCATTG ATTGAATGGG CGCCCGCGCC GAAACCACGC GATGCGACCG


 


851
TGCGTATGGT CGAGCCGGAC GAGCCGAAGT TTTCCGGATT TATCTTCAAA


 


901
ATCCAAGCCA ATATGGACCC GAAACACCGC GACCGTATTG CCTTCTTGCG


 


951
CGTCTGCTCC GGCAAATTCG AGCGCGGCAT GAAAATGAAA CACCTGCGTA


 


1001
TCAACCGCGA AATCGCCGCC TCCAGCGTGG TAACCTTCAT GTCCCACGAC


 


1051
CGCGAGCTGG TTGAAGAAGC CTACGCCGGC GACATTATCG GTATCCCAAA


 


1101
CCACGGCAAC ATCCAAATCG GCGACAGCTT CTCCGAAGGC GAACAACTGA


 


1151
CGTTTACCGG CATCCCATTC TTCGCGCCCG AACTGTTCCG CAGCGTTCGC


 


1201
ATCAAAAACC CGCTGAAAAT CAAGCAACTG CAAAAAGGTT TGCAACAGCT


 


1251
TGGCGAAGAA GGTGCGGTGC AGGTGTTCAA ACCAATGAGC GGCGCGGATT


 


1301
TGATTTTGGG CGCGGTCGGC GTGTTGCAGT TTGAAGTCGT TACCTCGCGC


 


1351
CTTGCCAACG AATACGGCGT GGAAGCCGTG TTCGACAACG CATCCATCTG


 


1401
GTCGGCGCGC TGGGTATCGT GCGACGACAA GAAAAAACTG GCGGAATTTG


 


1451
AAAAAGCCAA CGCGGGCAAC CTCGCCATCG ACGCGGGCGG CAACCTCGCC


 


1501
TACCTCGCCC CTAACCGCGT GAATCTGGGA CTCACGCAAG AACGCTGGCC


 


1551
GGACATCGTG TTCCACGAAA CGCGCGAGCA TTCGGTCAAA CTTTAA






This corresponds to the amino acid sequence <SEQ ID 516; ORF 134.a>:










a134.pep




1
MSQEILDQVR RRRTFAIISH PDAGKTTLTE KLLLFSGAIQ SAGTVKGKKT


 


51
GKFATSDWMD IEKQRGISVA SSVMQFDYKD HTVNLLDTPG HQDFSEDTYR


 


101
VLTAVDSALM VIDAAKGVEA QTIKLLNVCR LRNTPIVTFM NKYDREVRDS


 


151
LELLDEVENI LQIRCAPVTW PIGMGKNFKG VYHILNDEIY LFEAGGERLP


 


201
HEFDIIKGID NPELEQRFPL EIQQLRDEIE LVQAASNEFN LDEFLAGELT


 


251
PVFFGSAINN FGIQEILNSL IEWAPAPKPR DATVRMVEPD EPKFSGFIFK


 


301
IQANMDPKHR DRIAFLRVCS GKFERGMKMK HLRINREIAA SSVVTFMSHD


 


351
RELVEEAYAG DIIGIPNHGN IQIGDSFSEG EQLTFTGIPF FAPELFRSVR


 


401
IKNPLKIKQL QKGLQQLGEE GAVQVFKPMS GADLILGAVG VLQFEVVTSR


 


451
LANEYGVEAV FDNASIWSAR WVSCDDKKKL AEFEKANAGN LAIDAGGNLA


 


501
YLAPNRVNLG LTQERWPDIV FHETREHSVK L*






m134/a134 98.9% identity in 531 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 517>:










g135.seq




1
ATGAAATACA AAAGAATCGT ATTTAAAGTC GGCACATCTT CGATTACCCG


 


51
TTCGGAcgGC AGCCTCTCGC GCGGCAAAAT CCAAACCATC ACCCGCCAGC


 


101
TTGCCGCATT GCATCATGCG GGACACGAGC TGGTCTTGGT GTCTTCCGGC


 


151
GCGGTTGCTG CAGGGTTCGG CGCGCTGGGT TTCAAAAAAC GTCCGGTCAA


 


201
AATCGCCGAC AAACAGGCTT CCGCCGCCGT CGGGCAGGGG CTGCTGATGG


 


251
AAGAATATAC GGCAAACCTG TCTTCAGACG GCATCGTGTC CGCACAAATC


 


301
CTGCTCAGCC GTGCCGACTT TGCCGACAAA CGCCGCTACC AAAATGCCGG


 


351
CGGCGCACTT TCCGTGCTGC TGCAACGCCG CGCGATTCCC ATCATCAATG


 


401
AAAACGACAC GGTTTCGGTT GAGGAGTTGA AAATCGGCGA CAACGACACA


 


451
TTGAGTGCGC AAGTGGCGGC GATGATACAG GCAGACCTCT TGGTGCTGCT


 


501
GACCGACATA GACGGTCTTT ACACCGGCAA CCCGAACAGC AATCCCGATG


 


551
CCGTACGGCT GGACAAAATC GAACACATCA ACCATGAAAT CATCGAAATG


 


601
GCGGGCGGCT CGGGTTCGGC AAACGGCACG GGCGGTATGC TGACCAAAAT


 


651
CAAAGCGGCA ACCATCGCCG CCGAATCCGG CGTACCGGTG TATATCTGTT


 


701
CCTCACTCAA ACCCGATTCA TTGGCCGAAG CCGCCGAACA TCAGGCGGAC


 


751
GGCTCGTTTT TCGTcccCcg tgCCAAAGGT TTGCGGACAC AGAAGCAATG


 


801
GctggCGTTC TATTCcgaaa gcggGGgcag cgttTAtgtg gacgaaagtg


 


851
cggaacacgc tTtgtccgaa caagggaaag cctgCTGA






This corresponds to the amino acid sequence <SEQ ID 518; ORF 135.ng>:










g135.pep




1
MKYKRIVFKV GTSSITRSDG SLSRGKIQTI TRQLAALHHA GHELVLVSSG


 


51
AVAAGFGALG FKKRPVKIAD KQASAAVGQG LLMEEYTANL SSDGIVSAQI


 


101
LLSRADFADK RRYQNAGGAL SVLLQRRAIP IINENDTVSV EELKIGDNDT


 


151
LSAQVAAMIQ ADLLVLLTDI DGLYTGNPNS NPDAVRLDKI EHINHEIIEM


 


201
AGGSGSANGT GGMLTKIKAA TIAAESGVPV YICSSLKPDS LAEAAEHQAD


 


251
GSFFVPRAKG LRTQKQWLAF YSESGGSVYV DESAEHALSE QGKAC*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 519>:










m135.seq




1
ATGAAATACA AAAGAATCGT ATTTAAAGTC GGCACATCTT CGATTACCCA


 


51
TTCGGACGGC AGTCTCTCGC GCGGCAAAAT CCAAACCATC ACCTGCCAGC


 


101
TTGCCGCATT GCATCATGCG GGACACGAGC TGGTCTTGGT GTCTTCCGGC


 


151
GCGGTTGCGG CAGGGTTCGG TGCGCTGGGT TTCAAAAAAC GTCCGGTCAA


 


201
AATCGCCGAC AAACAGGCTT CCGCCGCCGT CGGGCAGGGG CTGCTGATGG


 


251
AAGAATATAC GGCAAACCTG TCTTCAGACG GCATCGTGTC CGCGCAAATC


 


301
CTGCTCAGCC GCGCCGACTT TGCCGACAAA CGCCGCTACC AAAATGCCGG


 


351
CGGCGCACTT TCCGTGCTGC TGCAACGCCG CGCCGTCCCC ATCATCAATG


 


401
AAAACGATAC GGTTTCGGTT GAGGAATTGA AAATCGGCGA CAACGACACA


 


451
TTGAGTGCGC AAGTGGCGGC GATGATACAG GCAGACCTCT TGGTGCTGCT


 


501
GACCGACATA GACGGTCTTT ACACGGGCAA CCCGAACAGC AATCCCGATG


 


551
CCGTACGGCT GGACAAAATC GAACACATCA ACCATGAAAT CATCGAAATG


 


601
GCGGGCGGCT CGGGTTCGGC AAACGGCACG GGCGGTATGC TGACCAAAAT


 


651
CAAAGCGGCA ACCATCGCCG CCGAATCCGG CGTACCGGTG TATATCTGTT


 


701
CCTCGCTCAA ACCCGATGCA CTTGCCGAAG CTGCCGAACA TCAGGCGGAC


 


751
GGCTCGTTTT TCGTCCCCCG TGCCAAAGGT TTGCGGACGC AGAAGCAATG


 


801
GCTGGCGTTC TATTCCGAAA GCCGGGGCAG CGTTTATGTG GACGAAGGTG


 


851
CGGAACACGC TTTGTCCGAA CAGGGGAAAA GCCTGCTGAT GTCGGGCATT


 


901
GCCGGAATCG AAGGGCATTT TTCCCGTATG GACACCGTAA CCGTGTACAG


 


951
CAAGGCAACC AAACAGCCCC TGGGCAAAGG GCGCGTCCTG TTCGGCTCTG


 


1001
CCGCCGCCGA AGACCTGCTC AAATCGCGTA AGGCGAAAGG CGTGTTCATC


 


1051
CATCGGGACG ACTGGATTTC CATCACGCCC GAAATACGCC TGCTTCTGAC


 


1101
CGAATTTTAG






This corresponds to the amino acid sequence <SEQ ID 520; ORF 135>:










m135.pep




1
MKYKRIVFKV GTSSITHSDG SLSRGKIQTI TCQLAALHHA GHELVLVSSG


 


51
AVAAGFGALG FKKRPVKIAD KQASAAVGQG LLMEEYTANL SSDGIVSAQI


 


101
LLSRADFADK RRYQNAGGAL SVLLQRRAVP IINENDTVSV EELKIGDNDT


 


151
LSAQVAAMIQ ADLLVLLTDI DGLYTGNPNS NPDAVRLDKI EHINHEIIEM


 


201
AGGSGSANGT GGMLTKIKAA TIAAESGVPV YICSSLKPDA LAEAAEHQAD


 


251
GSFFVPRAKG LRTQKQWLAF YSESRGSVYV DEGAEHALSE QGKSLLMSGI


 


301
AGIEGHFSRM DTVTVYSKAT KQPLGKGRVL FGSAAAEDLL KSRKAKGVFI


 


351
HRDDWISITP EIRLLLTEF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 135 shows 97.6% identity over a 294 aa overlap with a predicted ORF (ORF 135.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 521>:










a135.seq




1
ATGAAATACA AAAGAATCGT ATTTAAAGTC GGCACATCTT CGATTACCCA


 


51
TTCGGACGGC AGTCTCTCGC GCGGCAAAAT CCAAACCATC ACCCGCCAGC


 


101
TTGCCGCATT GCATCATGCG GGACACGAGC TGGTCTTGGT GTCTTCCGGC


 


151
GCGGTTGCGG CAGGGTTCGG TGCGCTGGGT TTCAAAAAAC GTCCGGTCAA


 


201
AATCGCCGAC AAACAGGCTT CCGCCGCCGT CGGGCAGGGG CTGCTGATGG


 


251
AAGAATATAC GGCAAACCTG TCTTCAGACG GCATCGTGTC CGCACAAATC


 


301
CTGCTCAGCC GCGCCGACTT TGCCGACAAA CGCCGCTACC AAAATGCCGG


 


351
CGGCGCACTT TCCGTGCTGC TGCAACGCCG CGCCGTCCCC ATCATCAATG


 


401
AAAACGATAC GGTTTCGGTT GAGGAATTGA AAATCGGCGA CAACGACACA


 


451
TTGAGTGCGC AAGTGGCGGC GATGATACAG GCAGACCTCT TGGTGCTGCT


 


501
GACCGACATA GACGGTCTTT ACACCGGCAA CCCGAACAGC AATCCCGATG


 


551
CCGTACGGCT GGACAAAATC GAACACATCA ACCATGAAAT CATCGAAATG


 


601
GCGGGCGGCT CGGGTTCGGC AAACGGCACA GGCGGTATGC TGACTAAAAT


 


651
CAAAGCGGCG ACGATTGCGA CCGAGTCCGG CGTACCGGTC TATATCTGTT


 


701
CCTCGCTCAA ACCCGATGCA CTTGCCGAAG CGGCAGATAA TCAGGCGGAC


 


751
GGCTCGTTTT TCGTCCCCCG TGCCAAAGGT TTGCGGACGC AGAAGCAATG


 


801
GCTGGCGTTC TATTCCGAAA GCAGGGGCGG CGTTTATGTG GACGAAGGTG


 


851
CGGAACACGC TTTGTCCGAA CAGGGAAAAA GCCTGCTGAT GTCGGGCATT


 


901
GCCGGAATCG AAGGGCATTT TTCCCGTATG GACACCGTAA CCGTGTACAG


 


951
CAAGGCAACC AAACAGCCTT TGGGCAAAGG GCGAGTCCTG TTCGGCTCTG


 


1001
CCGCCGCCGA AGACCTGCTC AAATTGCGTA AGGCGAAAGG CGTGTTCATC


 


1051
CATCGGGACG ACTGGATTTC CATCACGCCC GAAATACGCC TGCTTCTGAC


 


1101
CGAATTTTAG






This corresponds to the amino acid sequence <SEQ ID 522; ORF 135.a>:










a135.pep




1
MKYKRIVFKV GTSSITHSDG SLSRGKIQTI TRQLAALHHA GHELVLVSSG


 


51
AVAAGFGALG FKKRPVKIAD KQASAAVGQG LLMEEYTANL SSDGIVSAQI


 


101
LLSRADFADK RRYQNAGGAL SVLLQRRAVP IINENDTVSV EELKIGDNDT


 


151
LSAQVAAMIQ ADLLVLLTDI DGLYTGNPNS NPDAVRLDKI EHINHEIIEM


 


201
AGGSGSANGT GGMLTKIKAA TIATESGVPV YICSSLKPDA LAEAADNQAD


 


251
GSFFVPRAKG LRTQKQWLAF YSESRGGVYV DEGAEHALSE QGKSLLMSGI


 


301
AGIEGHFSRM DTVTVYSKAT KQPLGKGRVL FGSAAAEDLL KLRKAKGVFI


 


351
HRDDWISITP EIRLLLTEF*






m135/a135 98.4% identity in 369 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 523>:










g136.seq




1
ATGGAAATCC GGTTTCAGAC AGCATTTTTA CGTTTGGTTC AGatgaAAAC


 


51
AAACGCTtca aTTCTtaccg caACACGCCT TGTATTTCCT GccgCTGCCG


 


101
CACGGACAGG GATCGTTCCT GCCGgtTTTT TCCCCTTCCC TGCGGACGGT


 


151
TTGCGGTTTG TTGATGACCG CCTGCCAGTA GCGGTAGATG TCtgccagcg


 


201
cgTAAGGCag tTCGGAcgca agttccgcca gctcgccttc ggTGAATTGC


 


251
AGgcggataa cgccgtttTC CTCTTCGTCg taaatgccgc ccactgccat


 


301
cacgGGGTAA AACAGCTCTT CAAACGCTTC ATCATCGGCG GCTTCAAACC


 


351
AATCGGTCGG CACAATGTCC AAACCGTAAA GATAGGCGTT GCACCAAGTG


 


401
TAAAAATCGC TGCCGCCCTC GCCGTCGTCG TAGAGCCACA AATCGGGCAG


 


451
CTTTTTATCC GACATCGCGG CGGTTGTTTC CATCGCCATT GCCAAAACCA


 


501
GCCGTTCGAT TTCGGAACGT TCGGCGGCGG TAAATTGCGA TTCGTCGCCC


 


551
AACACTTCGG GCAGCCAGTC GAGCGGTGCC AATTTGTCCG GCCCGCTCAA


 


601
CAGCGCCGTC ATAAAACCTT GAACCTCGTC GCAACGCATC GTGTTGCCTT


 


651
GTTCGCTTTT GGCATCCAAT AA






This corresponds to the amino acid sequence <SEQ ID 524; ORF 136.ng>:










g136.pep




1
MEIRFQTAFL RLVQMKTNAS ILTATRLVFP AAAARTGIVP AGFFPFPADG


 


51
LRFVDDRLPV AVDVCQRVRQ FGRKFRQLAF GELQADNAVF LFVVNAAHCH


 


101
HGVKQLFKRF IIGGFKPIGR HNVQTVKIGV APSVKIAAAL AVVVEPQIGQ


 


151
LFIRHRGGCF HRHCQNQPFD FGTFGGGKLR FVAQHFGQPV ERCQFVRPAQ


 


201
QRRHKTLNLV ATHRVALFAF GIQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 525>:










m136.seq




1
ATGGAAACAA ACGCTTCAAT TCTTACCGCA ACACGCCTTG TATTTTCTGC


 


51
CGCTGCCGCA CGGACAGGGA TCGTTCCTGC CTGTTTTTTC GCCTTCCCTG


 


101
CGGACGGTTT GCGGTTTGTT GATGACTGCC TGCCAGTAGC GGTAGATATC


 


151
CGCCAATGCA TAAGGCAACT CGGATTCCAG TTCCGCCAGC TCGCCTTCTG


 


201
TGAATTGCAG ACGGATAGCG CCGTTTTCCT CTTCGTCGTA AATACCGCCC


 


251
AATGCCATGA TGGGATAAAA CAACTCTTCA AACGCTTCAT CATCGACGGC


 


301
TTCAAACCAA TCGGTCGGCA CAATATCCAA ACCGTAAAGA TAAGCATTGC


 


351
ACCATGTGTA AAAATCGCTG CCGCCGTCTT CGTTTTCATA CAGCCACAAA


 


401
TCGGGCAGTT TTTTATCCGA CATCGCGGCG GTTGTTTCCA TCGCCATTGC


 


451
CAAAACCAGC CGTTCGATTT CGGAACGTTC GGCGGCGGTA AATTGCGATT


 


501
CGTCGCCCAA CACTTCGGGC AGCCAGTCGA GCGGTGTCAA TTTGTCCGGC


 


551
CCGCTCAACA GCGCCGTCAT AAAACCTTGA ACCTCGTCGC AACGCATCGT


 


601
GTTGCCTTGT TCGCTTTTGG CATCCAACAA TTCGCTCAAC CGCCGTTTGG


 


651
ATGCTTCGGT AAATTTTCGG GAATCCATCA TTTTCCTTTT CAAATGGGTT


 


701
TTGCGCCCTA TTATCGCCGC AATGCCGTCT GA






This corresponds to the amino acid sequence <SEQ ID 526; ORF 136>:










m136.pep




1
METNASILTA TRLVFSAAAA RTGIVPACFF AFPADGLRFV DDCLPVAVDI


 


51
RQCIRQLGFQ FRQLAFCELQ TDSAVFLFVV NTAQCHDGIK QLFKRFIIDG


 


101
FKPIGRHNIQ TVKISIAPCV KIAAAVFVFI QPQIGQFFIR HRGGCFHRHC


 


151
QNQPFDFGTF GGGKLRFVAQ HFGQPVERCQ FVRPAQQRRH KTLNLVATHR


 


201
VALFAFGIQQ FAQPPFGCFG KFSGIHHFPF QMGFAPYYRR NAV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 136 shows 85.6% identity over a 209 aa overlap with a predicted ORF (ORF 136.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 527>:










a136.seq




1
ATGGAAACAA ACGCTTCAAT TCTTACCGCA ACACGCCTTG TATTTTCTGC


 


51
CGCTGCCGCA CGGACAGGGA TCGTTCCTGC CTGTTTTTTC GCCTTCCCTG


 


101
CGGACGGTTT GCGGCTTGTT GATGACCGCC TGCCAGTAGC GGTAGATATC


 


151
CGCCAATGCA TAAGGCAACT CGGATTCCAG TTCCGCCAGC TCGCCTTCTG


 


201
TGAATTGCAG ACGGATAGTG CCGTTGTCCT CTTCGTCGTA AATACCGCCC


 


251
AATGCCATGA TGGGATAAAA CAACTCTTCA AACGCTTCAT CATCGACGGC


 


301
TTCAAACCAA TCGGTCGGCA CAATATCCAA ACCGTAAAGA TAAGCATTGC


 


351
ACCATGTGTA AAAATCGCTG CCGCCGTCTT CGTTTTCATA CAGCCACAAA


 


401
TCGGGCAGTT TTTTATCCGA CATCGCGGCG GTTGTTTCCA TCGCCATTGC


 


451
CAAAACCAGC CGTTCGATTT CGGAACGTTC GGCGGCGGTA AATTGCGATT


 


501
CGTCGCCCAA CACTTCGGGC AGCCAGTCGA GCGGTGTCAA TTTGTCCGGC


 


551
CCGCTCAACA GCGCCGTCAT AAAACCTTGA ACCTCGTCGC AACGCATCGT


 


601
GTTGCCTTGT TCGCTTTTGG CATCCAACAA TTCGCTCAAC CGCCGTTTGG


 


651
ATGCTTCGGT AAATTTTCGG GAATCCATCA TTTTCCTTTT CCAATGGGTT


 


701
TTGCGCCCTA TTATAGTGGA TTAAATTTAA ATCAGGACAA GGCGACGAAG


 


751
CCGCAGACAG TACAAATAGT ACGGCAAGGC GAGGCAACGC CGTACTGGTT


 


801
TAAATTTAAT CCACTATATC GCCGCAATGC CGTCTGA






This corresponds to the amino acid sequence <SEQ ID 528; ORF 136.a>:










a136.pep




1
METNASILTA TRLVFSAAAA RTGIVPACFF AFPADGLRLV DDRLPVAVDI


 


51
RQCIRQLGFQ FRQLAFCELQ TDSAVVLFVV NTAQCHDGIK QLFKRFIIDG


 


101
FKPIGRHNIQ TVKISIAPCV KIAAAVFVFI QPQIGQFFIR HRGGCFHRHC


 


151
QNQPFDFGTF GGGKLRFVAQ HFGQPVERCQ FVRPAQQRRH KTLNLVATHR


 


201
VALFAFGIQQ FAQPPFGCFG KFSGIHHFPF PMGFAPYYSG LNLNQDKATK


 


251
PQTVQIVRQG EATPYWFKFN PLYRRNAV*






m136/a136 98.3% identity in 238 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 529>:










g137.seq




1
ATGATTATCC ATCACcaaTT CGATCCCGTC CTCATCAGTA TCGGCCCGCT


 


51
TGCCGTCCGC TGGTATGCCT TAAGCTACAT CCTCGGATTT ATTCTTTTTA


 


101
CCTTTCTCGG CAGAAGGCGC ATCGCGCAAG GCTTGTCCGT TTTTACCAAA


 


151
GAATCGCTCG ACGACTTCCT GACATGGGGC ATTTTGGGCG TGATTTTGGG


 


201
CGGACGCTTG GGCTATGTCC TGTTTTACAA ATTCTCCGAC TACCTCGCCC


 


251
ATCCGCTTGA TATTTTCAAG GTATGGGAAG GCGGAATGTC GTTCCACGGC


 


301
GGCTTTTTGG GTGTAGTTAT TGCCATATGG TTGTTCAGCC GCAAGCACGG


 


351
CATCGGCTTC CTCAAACTGA TGGACACGGT CGCGCCGCTC GTTCCGCTGG


 


401
GTCTCGCTTC GGGACGTATC GGCAACTTTA TCAACGGCGA ACTTTGGGGA


 


451
CGCATTACCG ACATTAACGC ATTTTGGGCA ATGGGCTTCC CGCAAGCGCA


 


501
TTACGAAGAT GCCGAAGCCG CCGCGCACAA TCCGCTTTGG GCAGAATGGC


 


551
TGCAACAATA CGGTATGCTG CCGCGTCATC CCTCGCAGCT TTATCAGTTT


 


601
GCCCTTGAAG GCATCTGCCT GTTCGCCGTC GTTTGGCTGT TTTCCAAAAA


 


651
ACCGCGCCCG ACCGGGCAGA CTGCCGCGCT TTTTCTCGGC GGCTACGGCG


 


701
TGTTCCGCTT TATTGCCGAA TTTGCGCGCC AACCCGACGA CTATCTCGGG


 


751
CTGCTGACCT TGGGGCTGTC GATGGGGCAA TGGTTGAGCG TCCCGATGAT


 


801
TGTTTTGGGT ATCGTCGGCT TTGTCCGGTT CGGCATGAAA AAACAGCACT


 


851
GA






This corresponds to the amino acid sequence <SEQ ID 530; ORF 137.ng>:










g137.pep




1
MIIHHQFDPV LISIGPLAVR WYALSYILGF ILFTFLGRRR IAQGLSVFTK


 


51
ESLDDFLTWG ILGVILGGRL GYVLFYKFSD YLAHPLDIFK VWEGGMSFHG


 


101
GFLGVVIAIW LFSRKHGIGF LKLMDTVAPL VPLGLASGRI GNFINGELWG


 


151
RITDINAFWA MGFPQAHYED AEAAAHNPLW AEWLQQYGML PRHPSQLYQF


 


201
ALEGICLFAV VWLFSKKPRP TGQTAALFLG GYGVFRFIAE FARQPDDYLG


 


251
LLTLGLSMGQ WLSVPMIVLG IVGFVRFGMK KQH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 531>:










m137.seq




1
ATGATTACCC ATCCCCAATT CGATCCCGTC CTTATCAGTA TCGGCCCGCT


 


51
TGCCGTCCGC TGGTATGCCC TAAGCTACAT CCTCGGATTT ATTCTTTTTA


 


101
CCTTTCTCGG CAGAAGGCGC ATCGCGCAAG GCTTGTCCGT TTTTACCAAA


 


151
GAATCGCTCG ACGACTTCCT GACATGGGGC ATTTTGGGCG TAATTTTGGG


 


201
CGGGCGTTTG GGTTACGTCC TGTTTTACAA GTTTTCCGAC TACCTCGCCC


 


251
ATCCGCTTGA TATTTTCAAG GTATGGGAAG GCGGAATGTC GTTCCACGGC


 


301
GGCTTTTTGG GTGTAGTTAT TGCCATACGG TTGTTCGGCC GCAAACACGG


 


351
CATCGGCTTC CTCAAACTGA TGGATACGGT CGCACCGCTC GTTCCGCTGG


 


401
GTCTCGCTTC GGGACGTATC GGCAACTTCA TCAACGGCGA ACTTTGGGGA


 


451
CGCGTTACCG ACATCAACGC ATTTTGGGCA ATGGGCTTCC CGCAGGCGCG


 


501
TTACGAAGAT GCCGAAGCCG CCGCGCACAA TCCGCTTTGG GCAGAATGGC


 


551
TGCAACAATA CGGTATGCTG CCGCGTCATC CCTCGCAGCT TTATCAGTTT


 


601
GCACTTGAAG GCATCTGCCT GTTCACCGTC ATTTGGCTGT TCTCTAAAAA


 


651
ACAGCGGTCG ACCGGACAAG TCGCCTCGCT CTTCCTCGGC GGCTACGGCA


 


701
TATTCCGCTT CATTGCCGAA TTCGCACGCC AACCCGACGA CTATCTCGGG


 


751
CTGCTGACCT TGGGGCTGTC GATGGGGCAA TGGTTGAGCG TCCCGATGAT


 


801
TGTTTTGGGT ATCGTCGGCT TTGTCCGGTT CGGCATGAAA AAACAGCACT


 


851
GA






This corresponds to the amino acid sequence <SEQ ID 532; ORF 137>:










m137.pep




1
MITHPQFDPV LISIGPLAVR WYALSYILGF ILFTFLGRRR IAQGLSVFTK


 


51
ESLDDFLTWG ILGVILGGRL GYVLFYKFSD YLAHPLDIFK VWEGGMSFHG


 


101
GFLGVVIAIR LFGRKHGIGF LKLMDTVAPL VPLGLASGRI GNFINGELWG


 


151
RVTDINAFWA MGFPQARYED AEAAAHNPLW AEWLQQYGML PRHPSQLYQF


 


201
ALEGICLFTV IWLFSKKQRS TGQVASLFLG GYGIFRFIAE FARQPDDYLG


 


251
LLTLGLSMGQ WLSVPMIVLG IVGFVRFGMK KQH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 137 shows 95.4% identity over a 283 aa overlap with a predicted ORF (ORF 137.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 533>:










a137.seq




1
ATGATTACCC ATCCCCAATT CGACCCCGTC CTTATCAGTA TCGGCCCGCT


 


51
TGCCGTCCGC TGGTATGCCC TAAGCTACAT CCTCGGATTT ATTCTTTTTA


 


101
CCTTTCTCGG CAGAAGGCGC ATCGCGCAAG GCTTGTCCGT TTTTACCAAA


 


151
GAATCGCTCG ACGACTTCCT GACATGGGGC ATTTTGGGCG TAATTTTGGG


 


201
CGGGCGTTTG GGTTACGTCC TGTTTTACAA GTTTTCCGAC TACCTCGCCC


 


251
ATCCGCTTGA TATTTTCAAG GTATGGGAAG GCGGAATGTC GTTCCACGGC


 


301
GGCTTTTTGG GTGTAGTTAT TGCCATATGG TTGTTCGGTC GCAAACACGG


 


351
CATCGGCTTC CTCAAACTGA TGGACACGGT CGCACCGCTC GTTCCACTGG


 


401
GTCTCGCTTC GGGACGTATC GGCAACTTCA TCAACGGCGA ACTTTGGGGA


 


451
CGCGTTACCG ACATCAACGC ATTTTGGGCA ATGGGCTTCC CGCAGGCGCG


 


501
TTACGAAGAC CTCGAAGCCG CCGCGCACAA TCCGCTTTGG GCAGAATGGC


 


551
TGCAACAATA CGGTATGCTG CCGCGTCATC CCTCGCAGCT TTATCAGTTT


 


601
GCACTTGAAG GCATCTGCCT GTTCGCCGTC GTTTGGCTGT TCTCTAAAAA


 


651
ACAGCGGCCG ACCGGACAAG TCGCCTCACT CTTCCTCGGC GGCTACGGCA


 


701
TATTCCGCTT CATTGCCGAA TTTGCACGCC AACCCGACGA CTATCTCGGG


 


751
CTGCTGACCT TGGGGCTGTC GATGGGGCAA TGGTTGAGCG TCCCGATGAT


 


801
TGTTTTGGGT ATCGTCGGCT TTGTCCGGTT CGGCATGAAA AAACAGCACT


 


851
GA






This corresponds to the amino acid sequence <SEQ ID 534; ORF 137.a>:










a137.pep




1
MITHPQFDPV LISIGPLAVR WYALSYILGF ILFTFLGRRR IAQGLSVFTK


 


51
ESLDDFLTWG ILGVILGGRL GYVLFYKFSD YLAHPLDIFK VWEGGMSFHG


 


101
GFLGVVIAIW LFGRKHGIGF LKLMDTVAPL VPLGLASGRI GNFINGELWG


 


151
RVTDINAFWA MGFPQARYED LEAAAHNPLW AEWLQQYGML PRHPSQLYQF


 


201
ALEGICLFAV VWLFSKKQRP TGQVASLFLG GYGIFRFIAE FARQPDDYLG


 


251
LLTLGLSMGQ WLSVPMIVLG IVGFVRFGMK KQH*






m137/a137 98.2% identity in 283 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 535>:










g138.seq




1
ATGGAGTTTG AAAACATTAT TTCCGCCGCc gaCAAGGCGC GTATCCTTGC


 


51
CGAAGCACTG CCTTACAtcc gccgGTTTTC CGGTTCGGTC GCCGTCATCA


 


101
AGTATGGCGG CAACGCGATG ACCGAACCTG CCTTGAAAGA AGGGTTTGCC


 


151
CGCGATGTCG TGCTGCTGAA GCTGGTCGGC ATTCATCCCG TCATCGTTCA


 


201
CGGCGGCGGG CCGCAGATCA ATGCGATGCT TGAAAAAGTC GGCAAAAAGG


 


251
GCGAATTTGT CCAAGGAATG CGCGTTACCG ACAAAGAGAC GATGGATATT


 


301
GTCGAAATGG TATTGGGCGG GCACGTCAAC AAGGAAATCG TGTCGATGAT


 


351
TAACACATAT GGAGGGCACG CGGTCGGCGT GAGCGGGCGC GACGACCATT


 


401
TCATTAAGGC GAAGAAACTT TTGGTCGATA CGCCCGAACA GAATAGCGTG


 


451
GACATCGGAC AGGTCGGTAC GGTGGAAAGC ATCGATACCG GTTTGGTTAA


 


501
AGGGCTGATA GAACGCGGCT GCATTCCCGT CGTCGCCCCC GTCGGCGTAG


 


551
GTGAAAAAGG CGAAGCGTTC AACATCAACG CCGATTTGGT GGCAGGCAAA


 


601
TTGGCGGAAG AATTGAACGC CGAAAAACTC TTGATGATGA CGAAtatcgc


 


651
cgGTGTGATG GACAAAACGG GCAATCTGCT GACCAAACTC acgCCGAAAC


 


701
GGATTGATGG GCTGATTGCC GACGGCACGC TGTATGGCGG TATGCTGCCG


 


751
AAAATCGCTT CTGCGGTCGA AGCcgccgtc aACGGTGTGA AAGCCACGCA


 


801
CATCATCGAC GGCAGGTTGC CCAACGCGCT TTTGCTGGAA ATCTTTACCG


 


851
ATGCCGGTAT CGGGTCGATG ATTTTAGGCA GAGGGGAAGA TGCCTGA






This corresponds to the amino acid sequence <SEQ ID 536; ORF 138.ng>:










g138.pep




1
MEFENIISAA DKARILAEAL PYIRRFSGSV AVIKYGGNAM TEPALKEGFA


 


51
RDVVLLKLVG IHPVIVHGGG PQINAMLEKV GKKGEFVQGM RVTDKETMDI


 


101
VEMVLGGHVN KEIVSMINTY GGHAVGVSGR DDHFIKAKKL LVDTPEQNSV


 


151
DIGQVGTVES IDTGLVKGLI ERGCIPVVAP VGVGEKGEAF NINADLVAGK


 


201
LAEELNAEKL LMMTNIAGVM DKTGNLLTKL TPKRIDGLIA DGTLYGGMLP


 


251
KIASAVEAAV NGVKATHIID GRLPNALLLE IFTDAGIGSM ILGRGEDA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 537>:










m138.seq




1
ATGGAGTCTG AAAACATTAT TTCCGCCGCC GACAAGGCGC GTATCCTTGC


 


51
CGAAGCGCTG CCTTACATCC GCCGGTTTTC CGGTTCGGTC GCCGTCATCA


 


101
AATACGGCGG CAACGCGATG ACCGAACCTG CCTTGAAAGA AGGGTTTGCC


 


151
CGCGATGTCG TGCTGCTGAA GCTGGTCGGC ATTCATCCCG TCATCGTTCA


 


201
CGGCGGCGGG CCGCAGATCA ATGCGATGCT TGAAAAAGTC GGCAAAAAGG


 


251
GTGAGTTTGT CCAAGGAATG CGCGTTACCG ACAAAGAGGC GATGGATATT


 


301
GTCGAAATGG TGTTGGGCGG GCATGTCAAT AAAGAAATCG TGTCGATGAT


 


351
TAACACATAT GGCGGACACG CGGTCGGCGT AAGCGGACGC GACGACCATT


 


401
TCATTAAGGC GAAGAAACTT TTGATCGATA CGCCCGAACA GAATGGCGTG


 


451
GACATCGGAC AGGTCGGTAC GGTGGAAAGC ATCGATACCG GTTTGGTTAA


 


501
AGGGCTGATA GAACGTGGCT GCATTCCCGT CGTCGCCCCC GTCGGCGTAG


 


551
GTGAAAAAGG CGAAGCGTTC AACATCAACG CCGATTTGGT AGCAGGCAAA


 


601
TTGGCGGAAG AATTGAACGC CGAAAAACTC TTGATGATGA CGAATATCGC


 


651
CGGTGTGATG GACAAAACGG GCAATCTGCT GACCAAACTC ACGCCGAAAC


 


701
GGATTGATGA ACTGATTGCC GACGGCACGC TGTATGGCGG TATGCTGCCG


 


751
AAAATCGCTT CTGCGGTCGA AGCCGCCGTC AACGGTGTGA AAGCCACGCA


 


801
TATCATCGAC GGCAGGTTGC CCAACGCGCT TTTGCTGGAA ATCTTTACCG


 


851
ATGCCGGTAT CGGTTCGATG ATTTTGGGCG GTGGGGAAGA TGCCTGA






This corresponds to the amino acid sequence <SEQ ID 538; ORF 138>:










m138.pep




1
MESENIISAA DKARILAEAL PYIRRFSGSV AVIKYGGNAM TEPALKEGFA


 


51
RDVVLLKLVG IHPVIVHGGG PQINAMLEKV GKKGEFVQGM RVTDKEAMDI


 


101
VEMVLGGHVN KEIVSMINTY GGHAVGVSGR DDHFIKAKKL LIDTPEQNGV


 


151
DIGQVGTVES IDTGLVKGLI ERGCIPVVAP VGVGEKGEAF NINADLVAGK


 


201
LAEELNAEKL LMMTNIAGVM DKTGNLLTKL TPKRIDELIA DGTLYGGMLP


 


251
KIASAVEAAV NGVKATHIID GRLPNALLLE IFTDAGIGSM ILGGGEDA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 138 shows 98.0% identity over a 298 aa overlap with a predicted ORF (ORF 138.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 539>:










a138.seq




1
ATGGAGTCTG AAAACATTAT TTCCGCCGCC GACAAGGCGC GTATCCTTGC


 


51
CGAAGCGCTG CCTTACATCC GCCGGTTTTC CGGTTCGGTC GCCGTCATCA


 


101
AATACGGCGG CAACGCGATG ACCGAACCTG CCTTGAAAGA AGGGTTTGCC


 


151
CGCGATGTCG TGCTGCTGAA GCTGGTCGGC ATTCATCCCG TCATCGTTCA


 


201
CGGCGGCGGG CCGCAGATCA ATGCGATGCT TGAAAAAGTC GGCAAAAAGG


 


251
GTGAGTTTGT CCAAGGAATG CGCGTTACCG ACAAAGAGGC GATGGATATT


 


301
GTCGAAATGG TGTTGGGCGG GCATGTCAAT AAAGAAATCG TGTCGATGAT


 


351
TAACACATAT GGCGGACACG CGGTCGGCGT AAGCGGACGC GACGACCATT


 


401
TCATTAAGGC GAAGAAACTT TTGATCGATA CGCCCGAACA GAATGGCGTG


 


451
GACATCGGAC AGGTCGGTAC GGTGGAAAGC ATCGATACCG GTTTGGTTAA


 


501
AGGGCTGATA GAACGTGGCT GCATTCCCGT CGTCGCCCCC GTCGGCGTAG


 


551
GTGAAAAAGG CGAAGCGTTC AACATCAACG CCGATTTGGT AGCAGGCAAA


 


601
TTGGCGGAAG AATTGAACGC CGAAAAACTC TTGATGATGA CGAATATCGC


 


651
CGGTGTGATG GACAAAACGG GCAATCTGCT GACCAAACTC ACGCCGAAAC


 


701
GGATTGATGA ACTGATTGCC GACGGCACGC TGTATGGCGG TATGCTGCCG


 


751
AAAATCGCTT CTGCGGTCGA AGCCGCCGTC AACGGCGTGA AAGCCACGCA


 


801
TATCATCGAC GGCAGGGTGC CCAACGCGCT TTTGCTGGAA ATCTTTACCG


 


851
ATGCCGGTAT CGGTTCGATG ATTTTGGGCG GTGGGGAAGA TGCCTGA






This corresponds to the amino acid sequence <SEQ ID 540; ORF 138.a>:










a138.pep




1
MESENIISAA DKARILAEAL PYIRRFSGSV AVIKYGGNAM TEPALKEGFA


 


51
RDVVLLKLVG IHPVIVHGGG PQINAMLEKV GKKGEFVQGM RVTDKEAMDI


 


101
VEMVLGGHVN KEIVSMINTY GGHAVGVSGR DDHFIKAKKL LIDTPEQNGV


 


151
DIGQVGTVES IDTGLVKGLI ERGCIPVVAP VGVGEKGEAF NINADLVAGK


 


201
LAEELNAEKL LMMTNIAGVM DKTGNLLTKL TPKRIDELIA DGTLYGGMLP


 


251
KIASAVEAAV NGVKATHIID GRVPNALLLE IFTDAGIGSM ILGGGEDA*






m138/a138 99.7% identity in 298 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 541>:










g139.seq




1
ATGCGAACCA CCTCAACCTT CCCTACAAAA ACTTTCAAAC CGGCTGCCAT


 


51
GGCGTTAGCT GTTGCAACAA CACTTTCTGC CTGCTTAggc ggcggcggag


 


101
gcGGCACTTC TGCTCCCGAC TTTAATGCAG GCGGCACCGG TATCGGCAGC


 


151
AACAGCAGGG CAACGATAGC GGAATCAGCA GCAGTATCTT ACGCCGGTAT


 


201
AAAAAACGAA ATGTGCAAAG ACAGAAGCAT GCTCTGTGCC GGTCGGGATG


 


251
ACGTTGCGGT TACAGACAGG GATGCCAAAA TCAAAGCCCC CCGAATCTGC


 


301
ATACCGGAGA CTTTTCAAAC CCAAATGACC AATATTAAGA ATATGATCAA


 


351
CCTCAAACCT GCAATTGAAG CAGGCTATAC AGGACGCGGG GTAGAGGTAG


 


401
GTATCGTCGA TACAGGCGAA TCCGTCGGCA GCATATCCTT TCCCGAACTG


 


451
TATGGCAGAA AAGAACACGG CTATAACGAA AATTACAAAA ACAAATTACA


 


501
AAAACTATAC GGCGTATATG CGGAAGGAAG CGCCTGA






This corresponds to the amino acid sequence <SEQ ID 542; ORF 138.ng>:










g139.pep




1
MRTTSTFPTK TFKPAAMALA VATTLSACLG GGGGGTSAPD FNAGGTGIGS



 


51
NSRATIAESA AVSYAGIKNE MCKDRSMLCA GRDDVAVTDR DAKIKAPRIC


 


101
IPETFQTQMT NIKNMINLKP AIEAGYTGRG VEVGIVDTGE SVGSISFPEL


 


151
YGRKEHGYNE NYKNKLQKLY GVYAEGSA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 543>:










m139.seq




1
ATGCGAACGA CCCCAACCTT CCCTACAAAA ACTTTCAAAC CGACTGCCAT



 


51
GGCGTTAGCT GTTGCAACAA CACTTTCTGC CTGCTTAGGC GGCGGCGGAG


 


101
GCGGCACTTC TGCGCCCGAC TTCAATGCAG GCGGTACCGG TATCGGCAGC


 


151
AACAGCAGAG CAACAACAGC GAAATCAGCA GCAGTATCTT ACGCCGGTAT


 


201
CAAGAACGAA ATGTGCAAAG ACAGAAGCAT GCTCTGTGCC GGTCGGGATG


 


251
ACGTTGCGGT TACAGACAGG GATGCCAAAA TCAATGCCCC CCCCCGAATC


 


301
TGCATACCGG AGACTTTCCA AACCCAAATG ACGCATtACA AGAATTTGAT


 


351
CAACCTCAAA CCTGCAATTG AAGCAGGCTA TACAGGACGC GGGGTAGAGG


 


401
TAGGTATCGT CGACACAGGC GAATCCGTCG GCAGCATATC CTTTCCCGAA


 


451
CTGTATGGCA GAAAAGAACA CGGCTATAAC GAAAATTACG AAAAACTATA


 


501
CGGCGTATAT GCGGAAGGAA GCGCCTGA






This corresponds to the amino acid sequence <SEQ ID 544; ORF 138>:










m139.pep




1
MRTTPTFPTK TFKPTAMALA VATTLSACLG GGGGGTSAPD FNAGGTGIGS



 


51
NSRATTAKSA AVSYAGIKNE MCKDRSMLCA GRDDVAVTDR DAKINAPPRI


 


101
CIPETFQTQM THYKNLINLK PAIEAGYTGR GVEVGIVDTG ESVGSISFPE


 


151
LYGRKEHGYN ENYEKLYGVY AEGSA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 138 shows 92.2% identity over a 179 aa overlap with a predicted ORF (ORF 138.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 545>:










a139.seq




1
ATGCGAACGA CCCCAACCTT CCCTACAAAA ACTTTCAAAC CGGCTGCCAT



 


51
GGCGTTAGCT GTTGCAACAA CACTTTCTGC CTGCTTAGGC GGCGGCGGAG


 


101
GCGGCACTTC TGCGCCCGAC TTCAATGCAG GCGGCACCGG TATCGGCAGC


 


151
AACAGCAGGG CAACAACAGC GAAATCAGCA GCAATATCTT ACGCCGGTAT


 


201
CAAGAACGAA ATGTGCAAAG ACAGAAGCAT GCTCTGTGCC GGTCGGGATG


 


251
ACGTTGCGGT TACAGACAGG GATGCCAAAA TCAATGCCCC CCCCCGAATC


 


301
TGCATACCGG AGACTTTACA AACCCAAATG ACGCAT.ACA AGAATTTGAT


 


351
CAACCTCAAA CCTGCAATTG AAGCAGGCTA TACAGGACGC GGGGTAGAGG


 


401
TAGGTATCGT CGACACAGGC GAATCCGTCG GCAGCATATC CTTTCCCGAA


 


451
CTGTATGGCA GAAAAGAACA CGGCTATAAC GAAAATTAC. AAAAACTATA


 


501
CGGCGTATAT GCGGAAGGAA GCGCCTGA






This corresponds to the amino acid sequence <SEQ ID 546; ORF 139.a>:










a139.pep




1
MRTTPTFPTK TFKPAAMALA VATTLSACLG GGGGGTSAPD FNAGGTGIGS



 


51
NSRATTAKSA AISYAGIKNE MCKDRSMLCA GRDDVAVTDR DAKINAPPRI


 


101
CIPETLQTQM THXKNLINLK PAIEAGYTGR GVEVGIVDTG ESVGSISFPE


 


151
LYGRKEHGYN ENYXKLYGVY AEGSA*






m139/a139 97.1% identity in 175 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 547>:










g140.seq




1
Atgtcggcac gCGGCAAGGG GGCAGgctat ctcAACAGTA CCGGACGACa



 


51
TGTTCCCTTC CTGAGTGCCG CCAAAATCGG GCAGGATTAT TCTTTCTTCA


 


101
AAAATATCAA AACCGACGGC GGTCTGCTGG CTTCCCTCGA CAGCGTCGAA


 


151
AAAACAGCGG GCAGTGAAGG CGACACGCCG TCCTATTATG TCCGTCGCGG


 


201
CAATGCGGCA CGGACTGCTT CGGCAGCGGC ACATTCCGCG CCCGCCGGTC


 


251
TGAAACACGC CGTAGAACAG GGCGGCAGCA ATCTGGAAAA CCTGATGGTC


 


301
GAGCTGGATG CCTCCGAATC ATCCGCAACA CCCGAGACGG TTGAAACTGC


 


351
GGTCGCCGAC CGCACAGATA TGCCGGGCAT CCGCCTACGG CGCACAACTT


 


401
TCCGCACAGC GGCAGCCGTA CAGCATGCGA ATACCGCCGA CGGCGTACGc


 


451
aTCTTcaaCA GTCTCGCCGC TAccgTCTAt GccgACAGTG CCGCCGCCCA


 


501
TGccgATATG CAGGGACGCC GCCTGAAAGC CGTATCGGAC GGGTTGGACC


 


551
ACAACGGTAC GGGTCTGCGC GTCATCGCGC AAACCCAACA GGACGGTGGA


 


601
ACGTGGGAAC AGGGCGGTGT CGAAGGCAAA ATGCGCGGCA GTACCCAAAC


 


651
TATCGGCATT GCCGCGAAAA CCGGCGAAAA TACGACAGCA GCCGCCACAC


 


701
TGGGCATAGG ACGCAGCACA TGGAGCGAAA ACAGTGCAAA TGCAAAAACC


 


751
GACAGCATTA GTCTGTTTGC AGGCATACGG CACGATGTGG GCGATATCGG


 


801
CTATCTCAAA GGCCTGTTCT CctaCGGACG CTACAAAAAC AGCATCAGCC


 


851
GCAGCACCGG TGCGGATGAA TATGCGGAAG GCAGCGTCAA CGGCACGCTG


 


901
ATGCAGCTGG GCGCACTGGG TGGTGTCAAC GTTCCGTTTG CCGCAACGGG


 


951
AGATTTGACG GTTGAAGGCG GTCTGCGCCA CGACCTGCTC AAACAGGATG


 


1001
CATTCGCCGA AAAAGGCagt GCTTTGGGCT GGAGCGGCAA CAGCCTCACT


 


1051
GAAGGCACAC TGGTCGGACT CGCGGGTCTG AAACTGTCGC AACCCTTGAG


 


1101
CGATAAAGCC GTCCTGTCTG CGACGGCGGG CGTGGAACGC GACCTGAACG


 


1151
GACGCGACTA CGCGGTAACG GGCGGCTTTA CCGGCGCGGC TGCAGCAACC


 


1201
GGCAAGACGG GTGCACGCAA TATGCCGCAC ACCCGCCGGG TTGCCGGTCT


 


1251
GGGGGTGGAT GTCGAATTCG GCAACGGCTG GAACGGCTTG GCACGTTACA


 


1301
GCTACACCGG TTCCAAACAG TACGGCAACC ACAGCGGACA AATCGGCGTA


 


1351
GGCTACCGGT TCTGA






This corresponds to the amino acid sequence <SEQ ID 548; ORF 140.ng>:










g140.pep




1
MSARGKGAGY LNSTGRHVPF LSAAKIGQDY SFFKNIKTDG GLLASLDSVE



 


51
KTAGSEGDTP SYYVRRGNAA RTASAAAHSA PAGLKHAVEQ GGSNLENLMV


 


101
ELDASESSAT PETVETAVAD RTDMPGIRLR RTTFRTAAAV QHANTADGVR


 


151
IFNSLAATVY ADSAAAHADM QGRRLKAVSD GLDHNGTGLR VIAQTQQDGG


 


201
TWEQGGVEGK MRGSTQTIGI AAKTGENTTA AATLGIGRST WSENSANAKT


 


251
DSISLFAGIR HDVGDIGYLK GLFSYGRYKN SISRSTGADE YAEGSVNGTL


 


301
MQLGALGGVN VPFAATGDLT VEGGLRHDLL KQDAFAEKGS ALGWSGNSLT


 


351
EGTLVGLAGL KLSQPLSDKA VLSATAGVER DLNGRDYAVT GGFTGAAAAT


 


401
GKTGARNMPH TRRVAGLGVD VEFGNGWNGL ARYSYTGSKQ YGNHSGQIGV


 


451
GYRF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 549>:










m140.seq




1
ATGTCGGCAC GCGGCAAGGG GGCAGGCTAT CTCAACAGTA CCGGACGACG



 


51
TGTTCCCTTC CTGAGTGCCG CCAAAATCGG GCAGGATTAT TCTTTCTTCA


 


101
CAAACATCGA AACCGACGGC GGCCTGCTGG CTTCCCTCGA CAGCGTCGAA


 


151
AAAACAGCGG GCAGTGAAGG CGACACGCTG TCCTATTATG TCCGTCGCGG


 


201
CAATGCGGCA CGGACTGCTT CGGCAGCGGC ACATTCCGCG CCCGCCGGTC


 


251
TGAAACACGC CGTAGAACAG GGCGGCAGCA ATCTGGAAAA CCTGATGGTC


 


301
GAACTGGATG CCTCCGAATC ATCCGCAACA CCCGAGACGG TTGAAACTGC


 


351
GGCAGCCGAC CGCACAGATA TGCCGGGCAT CCGCCCCTAC GGCGCAACTT


 


401
TCCGCGCAGC GGCAGCCGTA CAGCATGCGA ATGCCGCCGA CGGTGTACGC


 


451
ATCTTCAACA GTCTCGCCGC TACCGTCTAT GCCGACAGTA CCGCCGCCCA


 


501
TGCCGATATG CAGGGACGCC GCCTGAAAGC CGTATCGGAC GGGTTGGACC


 


551
ACAACGGCAC GGGTCTGCGC GTCATCGCGC AAACCCAACA GGACGGTGGA


 


601
ACGTGGGAAC AGGGCGGTGT TGAAGGCAAA ATGCGCGGCA GTACCCAAAC


 


651
CGTCGGCATT GCCGCGAAAA CCGGCGAAAA TACGACAGCA GCCGCCACAC


 


701
TGGGCATGGG ACGCAGCACA TGGAGCGAAA ACAGTGCAAA TGCAAAAACC


 


751
GACAGCATTA GTCTGTTTGC AGGCATACGG CACGATGCGG GCGATATCGG


 


801
CTATCTCAAA GGCCTGTTCT CCTACGGACG CTACAAAAAC AGCATCAGCC


 


851
GCAGCACCGG TGCGGACGAA CATGCGGAAG GCAGCGTCAA CGGCACGCTG


 


901
ATGCAGCTGG GCGCACTGGG CGGTGTCAAC GTTCCGTTTG CCGCAACGGG


 


951
AGATTTGACG GTCGAAGGCG GTCTGCGCTA CGACCTGCTC AAACAGGATG


 


1001
CATTCGCCGA AAAAGGCAGT GCTTTGGGCT GGAGCGGCAA CAGCCTCACT


 


1051
GAAGGCACGC TGGTCGGACT CGCGGGTCTG AAGCTGTCGC AACCCTTGAG


 


1101
CGATAAAGCC GTCCTGTTTG CAACGGCGGG CGTGGAACGC GACCTGAACG


 


1151
GACGCGACTA CACGGTAACG GGCGGCTTTA CCGGCGCGAC TGCAGCAACC


 


1201
GGCAAGACGG GGGCACGCAA TATGCCGCAC ACCCGTCTGG TTGCCGGCCT


 


1251
GGGCGCGGAT GTCGAATTCG GCAACGGCTG GAACGGCTTG GCACGTTACA


 


1301
GCTACGCCGG TTCCAAACAG TACGGCAACC ACAGCGGACG AGTCGGCGTA


 


1351
GGCTACCGGT TCTGA






This corresponds to the amino acid sequence <SEQ ID 550; ORF 140>:










m140.pep




1
MSARGKGAGY LNSTGRRVPF LSAAKIGQDY SFFTNIETDG GLLASLDSVE



 


51
KTAGSEGDTL SYYVRRGNAA RTASAAAHSA PAGLKHAVEQ GGSNLENLMV


 


101
ELDASESSAT PETVETAAAD RTDMPGIRPY GATFRAAAAV QHANAADGVR


 


151
IFNSLAATVY ADSTAAHADM QGRRLKAVSD GLDHNGTGLR VIAQTQQDGG


 


201
TWEQGGVEGK MRGSTQTVGI AAKTGENTTA AATLGMGRST WSENSANAKT


 


251
DSISLFAGIR HDAGDIGYLK GLFSYGRYKN SISRSTGADE HAEGSVNGTL


 


301
MQLGALGGVN VPFAATGDLT VEGGLRYDLL KQDAFAEKGS ALGWSGNSLT


 


351
EGTLVGLAGL KLSQPLSDKA VLFATAGVER DLNGRDYTVT GGFTGATAAT


 


401
GKTGARNMPH TRLVAGLGAD VEFGNGWNGL ARYSYAGSKQ YGNHSGRVGV


 


451
GYRF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 140 shows 94.5% identity over a 454 aa overlap with a predicted ORF (ORF 140.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 551>:










a140.seq




1
ATGTCGGCAG GCGGTAAGGG GGCAGGCTAT CTCAACCGTA CCGGACAACG



 


51
TGTTCCCTTC CTGAGTGCCG CCAAAATCGG GCGGGATTAT TCTTTCTTCA


 


101
CAAACATCGA AACCGACGGC GGTCTGCTGG CTTCCCTCGA CAGCGTCGAA


 


151
AAAACAGCGG GTAGTGAAGG CGACACGCTG TCCTATTATG TCCGTCGCGG


 


201
CAATGCGGCA CGGACTGCTT CGGCAGCGGC ACATTCCGCG CCCGCCGGTC


 


251
TGAAACACGC CGTAGAACAG GGCGGCAGCA ATCTGGAAAA CCTGATGGTC


 


301
GAACTGGATG CCTCCGAATC ATCCGCAACA CCCGAGACGG TTGAAACTGC


 


351
GGCCGCCGAC CGCACAGATA TGCCGGGCAT CCGCCCCTAC GGCGCAACTT


 


401
TCCGCGCAGC GGCAGCCGTA CAGCATGCGA ATGCCGCCGA CGGTGTACGC


 


451
ATCTTCAACA ATCTCGCCGC TACCGTCTAT GCCGACAGTA CCGCCGCCCA


 


501
TGCCGATATG CAGGGACGCC GCCTGAAAGC CGTATCGGAC GGGTTGGACC


 


551
ACAACGCTAC GGGTCTGCGC GTCATCGCGC AAACCCAACA GGACGGTGGA


 


601
ACGTGGGAAC AGGGCGGTGT TGAAGGCAAA ATGCGCGGCA GTACCCAAAC


 


651
CGTCGGCATT GCCGCGAAAA CCGGCGAAAA TACGACAGCA GCCGCCACAC


 


701
TGGGCATGGG ACACAGCACA TGGAGCGAAA ACAGTGCAAA TGCAAAAACC


 


751
GACAGCATTA GTCTGTTTGC AGGCATACGG CACGATGCGG GCGATATCGG


 


801
CTATCTCAAA GGCCTGTTCT CCTACGGACG CTACAAAAAC AGCATCAGCC


 


851
GCAGCACCGG TGCGGACGAA CATGCGGAAG GCAGCGTCAA CGGCACGCTG


 


901
ATGCAGCTGG GCGCACTGGG CGGTGTCAAC GTTCCGTTTG CCGCAACGGG


 


951
AGATTTGACG GTCGAAGGCG GTCTGCGCTA CGACCTGCTC AAACAGGATG


 


1001
CATTCGCCGA AAAAGGCAGT GCTTTGGGCT GGAGCGGCAA CAGCATCACT


 


1051
GAAGGCACAC TGGTCGGACT CGCGGGTCTG AAGCTGTCGC AACCCTTGAG


 


1101
CGATAAAGCC GTCCTGTTTG CAACGGCGGG CGTGGAACGC GACCTGAACG


 


1151
GACGCGACTA CACGGTAACG GGCGGCTTTA CCGGCGCGAC TGCAGCAACC


 


1201
GGCAAGACGG GGGCACGCAA TATGCCGCAC ACCCGCCTGG TTGCCGGTCT


 


1251
GGGCGCGGAT GTCGAATTCG GCAACGGCTG GAACGGCTTG GCACGTTACA


 


1301
GCTACGCCGG TTCCAAACAG TACGGCAACC ACAGCGGACG AGTCGGCGTA


 


1351
GGCTACCGGT TCTGA






This corresponds to the amino acid sequence <SEQ ID 552; ORF 140.a>:










a140.pep




1
MSAGGKGAGY LNRTGQRVPF LSAAKIGRDY SFFTNIETDG GLLASLDSVE



 


51
KTAGSEGDTL SYYVRRGNAA RTASAAAHSA PAGLKHAVEQ GGSNLENLMV


 


101
ELDASESSAT PETVETAAAD RTDMPGIRPY GATFRAAAAV QHANAADGVR


 


151
IFNNLAATVY ADSTAAHADM QGRRLKAVSD GLDHNATGLR VIAQTQQDGG


 


201
TWEQGGVEGK MRGSTQTVGI AAKTGENTTA AATLGMGHST WSENSANAKT


 


251
DSISLFAGIR HDAGDIGYLK GLFSYGRYKN SISRSTGADE HAEGSVNGTL


 


301
MQLGALGGVN VPFAATGDLT VEGGLRYDLL KQDAFAEKGS ALGWSGNSIT


 


351
EGTLVGLAGL KLSQPLSDKA VLFATAGVER DLNGRDYTVT GGFTGATAAT


 


401
GKTGARNMPH TRLVAGLGAD VEFGNGWNGL ARYSYAGSKQ YGNHSGRVGV


 


451
GYRF*






m140/a140 98.2% identity in 454 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 553>:










g141.seq




1
atgagcttca aAAccgATGC CGAAACCGCC CAATCCTCCA CCATGCGCCC



 


51
GATTGGCGAA ATTGCCGCCA AGCTGGGTTT GAACGTTGAC AACATTGAGC


 


101
CTTACGGTCA TTACAAAGCC AAAATCAATC CTGCCGAAGC GTTCAAGCTG


 


151
CCGCAAAAAC AAGGCAGGCT GATTTTGGTT ACCGCCATCA ACCCGACTCC


 


201
GGCGGGCGAA GGCAAAACCA CCGTAACCAT CGGTTTGGCG GACGCATTGC


 


251
GCCATATCGG CAAAGACTCT GTGATTGCTT TGCGCGAGCC TTCTTTGGGT


 


301
CCGGTGTTCG GCGTGAAAGG CGGCGCGGCA GGCGGCGGCT ACGCGCAAGT


 


351
TTTGCCGATG GAAGACATCA ACCTGCACTT CACCGGCGAC TTCCACGCCA


 


401
TCGGTGCGGC GAATAACCTC CTCGCCGCCA TGCTCGACAA CCATATCTAC


 


451
CAAGGTAACG AGTTGAACAT CGACCCCAAA CGCGTGCTGT GGCGGCGCGT


 


501
GGTCGATATG AACGACCGCC AGTTGCGCAA CATCATCGAC GGTATGGGCA


 


551
AGCCTGTtga cggCGTGATG CGtcccGACG GCTTCGACAT CACCGTCGCC


 


601
TCCGAAGTGa tggcgGTATT CTGCCTTGCC AAAGACATCA GCGATTTGAA


 


651
AGAGCGTTtt gGCAATATTC TCGTCGCCTA CGCCAAAGAC GGCAGCCCCG


 


701
TTTACGCCAA AGATTTGAAG GCACACGGCG CGATGGCGGC ATTGCTAAAA


 


751
GATGCGATTA AGCCCAATTT GGTGCAAACC ATCGAAGGCA CTCCGGCCTT


 


801
TGTACACGGC GGCCCGTTCG CCAACATCGC CCACGGCTGC AACTCCGTTA


 


851
CCGCAACCCG TCTGGCGAAA CACCTTGCCG ATTACGCCGT AACCGAAGCA


 


901
GGCTTCGGCG CGGACTTGGG TGCGGAAAAA TTCTGCGACA TCAAATGCCG


 


951
CCTTGCCGGT TTGAAACCTG ATGCGGCAGT CGTCGTGGCG ACTGTCCGCG


 


1001
CCCTGAAATA CAACGGCGGC GTGGAACGCG CCAACCTTGG TGAAGAAAAC


 


1051
CTCGAAGCCT TGGCAAAAGG TTTGCCCAAC CTGTTGAAAC ACATTTCCAA


 


1101
CCTGAAAAAC GTATTCGGAC TGCCCGTCGT CGTTGCGCTC AACCGCTTCG


 


1151
TGTCCGACTC CGATGCCGAG TTGGCGATGA TTGAAAAAGC CTGTGCCGAA


 


1201
CACGGCGTTG AAGTTTCCCT GACCGAAGTG TGGGGCAAAG GCGGCGCGGG


 


1251
CGGCGCGGAT TTGGCGCGCA AAGTCGTCAA TGCCATCGAC AACCAACCTA


 


1301
ATAACTTCGG TTTCGCCTAC GATGTCGAGT TGGGCATCAA AGACAAAATC


 


1351
CGTGCGATTG CCCAAAAAGT GTACGGCGCG GAAGATGTCG ATTTCAGCGC


 


1401
GGAAGCGTCT GCCGAAATCG CCTCGCTGGA AAAACTGGGC TTGGACAAAA


 


1451
TGCCGATCTG CATGGCGAAA ACCCAATATT CATTGAGCGA CAACGCCAAA


 


1501
CTCTTGGGCT GCCCCGAAGG CTTCCGCATC GCCGTACGCG GTATCACTGT


 


1551
TTCCGCCGGC GCGGGCTTCA TCGTTGCGTT GTGCGGCAAT ATGATGAAAA


 


1601
TGCCGGGCCT GCCGAAAGTT CCGGCTGCCG AGAAAATCGA TGTGGACGAA


 


1651
CACGGCGTGA TTCACGGCTT GTTCTGA






This corresponds to the amino acid sequence <SEQ ID 554; ORF 141.ng>:










g141.pep




1
MSFKTDAETA QSSTMRPIGE IAAKLGLNVD NIEPYGHYKA KINPAEAFKL



 


51
PQKQGRLILV TAINPTPAGE GKTTVTIGLA DALRHIGKDS VIALREPSLG


 


101
PVFGVKGGAA GGGYAQVLPM EDINLHFTGD FHAIGAANNL LAAMLDNHIY


 


151
QGNELNIDPK RVLWRRVVDM NDRQLRNIID GMGKPVDGVM RPDGFDITVA


 


201
SEVMAVFCLA KDISDLKERF GNILVAYAKD GSPVYAKDLK AHGAMAALLK


 


251
DAIKPNLVQT IEGTPAFVHG GPFANIAHGC NSVTATRLAK HLADYAVTEA


 


301
GFGADLGAEK FCDIKCRLAG LKPDAAVVVA TVRALKYNGG VERANLGEEN


 


351
LEALAKGLPN LLKHISNLKN VFGLPVVVAL NRFVSDSDAE LAMIEKACAE


 


401
HGVEVSLTEV WGKGGAGGAD LARKVVNAID NQPNNFGFAY DVELGIKDKI


 


451
RAIAQKVYGA EDVDFSAEAS AEIASLEKLG LDKMPICMAK TQYSLSDNAK


 


501
LLGCPEGFRI AVRGITVSAG AGFIVALCGN MMKMPGLPKV PAAEKIDVDE


 


551
HGVIHGLF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 555>:










m141.seq




1
ATGAGCTTCA AAACCGATGC CGAAATCGCC CAATCCTCCA CCATGCGCCC



 


51
GATTGGCGAA ATTGCCGCCA AGCTTGGTCT GAATGCCGAC AACATTGAGC


 


101
CTTACGGTCA TTACAAGGCG AAAATCAATC CTGCCGAAGC GTTCAAACTG


 


151
CCGCAAAAAC AGGGCAGGCT GATTTTGGTT ACCGCCATCA ACCCGACTCC


 


201
GGCGGGCGAA GGCAAAACCA CCGTAACCAT CGGTTTGGCG GACGCGTTGC


 


251
GCCACATCGG CAAAGATGCC GTGATTGCCC TGCGCGAACC TTCTCTGGGG


 


301
CCGGTGTTCG GCGTGAAAGG CGGCGCGGCA GGCGGCGGCT ATGCCCAAGT


 


351
TTTGCCGATG GAAGACATCA ACCTGCACTT CACCGGAGAT TTTCACGCCA


 


401
TCGGTGCGGC AAATAATCTG CTTGCCGCGA TGCTCGACAA CCATATCTAC


 


451
CAAGGCAACG AGTTGAACAT CGACCCCAAA CGCGTGCTGT GGCGGCGCGT


 


501
GGTCGATATG AACGACCGCC AGTTGCGCAA CATCATCGAC GGCATGGGTA


 


551
AACCCGTTGA CGGCGTGATG CGTCCTGACG GTTTCGATAT TACCGTTGCT


 


601
TCCGAAGTGA TGGCGGTATT CTGTCTTGCC AAAGACATCA GCGATTTGAA


 


651
AGAGCGTTTG GGCAACATCC TTGTCGCCTA CGCCAAAGAC GGCAGCCCCG


 


701
TTTACGCCAA AGATTTGAAA GCGAATGGCG CGATGGCGGC ATTGCTTAAA


 


751
GATGCGATTA AGCCCAACTT GGTGCAAACC ATCGAAGGCA CGCCCGCCTT


 


801
CGTACACGGC GGCCCGTTCG CCAACATCGC CCACGGCTGC AACTCCGTAA


 


851
CCGCAACCCG TCTGGCGAAA CACCTTGCCG ATTACGCCGT AACCGAAGCA


 


901
GGCTTCGGCG CGGACTTGGG CGCGGAAAAA TTCTGCGACA TCAAATGCCG


 


951
CCTTGCCGGT TTGAAACCTG ATGCGGCTGT TGTCGTGGCG ACTGTCCGCG


 


1001
CGTTGAAATA TAACGGCGGC GTGGAACGCG CCAACCTCGG CGAAGAAAAT


 


1051
TTAGACGCTT TGGAAAAAGG TTTGCCCAAC CTGCTGAAAC ACATTTCCAA


 


1101
CCTGAAAAAC GTATTCGGAC TGCCCGTCGT CGTTGCGCTC AACCGCTTCG


 


1151
TGTCCGACGC CGATGCCGAG TTGGCGATGA TTGAAAAAGC CTGTGCCGAA


 


1201
CACGGCGTTG AAGTTTCCCT GACCGAAGTG TGGGGCAAAG GTGGTGCGGG


 


1251
CGGCGCGGAT TTGGCGCGCA AAGTCGTCAA CGCCATTGAA AGTCAAACCA


 


1301
ATAACTTCGG TTTCGCCTAC GATGTCGAGT TGGGCATCAA AGACAAAATC


 


1351
CGTGCGATTG CCCAAAAAGT GTACGGCGCG GAAGATGTTG ATTTCAGCGC


 


1401
GGAAGCGTCT GCCGAAATCG CTTCACTGGA AAAACTGGGC TTGGACAAAA


 


1451
TGCCGATCTG CATGGCGAAA ACCCAATACT CTTTGAGCGA CAACGCCAAA


 


1501
CTGTTGGGCT GCCCCGAAGA CTTCCGCATC GCCGTGCGCG GCATCACCGT


 


1551
TTCCGCAGGC GCAGGTTTCA TCGTCGCCCT GTGCGGCAAC ATGATGAAAA


 


1601
TGCCCGGCCT GCCCAAAGTT CCGGCTGCCG AGAAAATCGA TGTGGACGCA


 


1651
GAAGGCGTGA TTCACGGCTT GTTCTGA






This corresponds to the amino acid sequence <SEQ ID 556; ORF 141>:










m141.pep




1
MSFKTDAEIA QSSTMRPIGE IAAKLGLNAD NIEPYGHYKA KINPAEAFKL



 


51
PQKQGRLILV TAINPTPAGE GKTTVTIGLA DALRHIGKDA VIALREPSLG


 


101
PVFGVKGGAA GGGYAQVLPM EDINLHFTGD FHAIGAANNL LAAMLDNHIY


 


151
QGNELNIDPK RVLWRRVVDM NDRQLRNIID GMGKPVDGVM RPDGFDITVA


 


201
SEVMAVFCLA KDISDLKERL GNILVAYAKD GSPVYAKDLK ANGAMAALLK


 


251
DAIKPNLVQT IEGTPAFVHG GPFANIAHGC NSVTATRLAK HLADYAVTEA


 


301
GFGADLGAEK FCDIKCRLAG LKPDAAVVVA TVRALKYNGG VERANLGEEN


 


351
LDALEKGLPN LLKHISNLKN VFGLPVVVAL NRFVSDADAE LAMIEKACAE


 


401
HGVEVSLTEV WGKGGAGGAD LARKVVNAIE SQTNNFGFAY DVELGIKDKI


 


451
RAIAQKVYGA EDVDFSAEAS AEIASLEKLG LDKMPICMAK TQYSLSDNAK


 


501
LLGCPEDFRI AVRGITVSAG AGFIVALCGN MMKMPGLPKV PAAEKIDVDA


 


551
EGVIHGLF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 141 shows 97.5% identity over a 558 aa overlap with a predicted ORF (ORF 141.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 557>:










a141.seq




1
ATGAGTTTCA AAACCGATGC CGAAATCGCC CAATCCTCCA CCATGCGCCC


 


51
GATTGGCGAA ATTGCCGCCA AGCTGGGTTT GAACGTTGAC AACATTGAGC


 


101
CTTACGGTCA TTACAAAGCC AAAATCAATC CTGCCGAAGC GTTCAAACTG


 


151
CCGCAAAAAC AGGGCAGGCT GATTTTGGTT ACCGCCATCA ACCCGACTCC


 


201
GGCGGGCGAA GGTAAAACCA CCGTAACCAT CGGTTTGGCG GACGCATTGC


 


251
GCCATATCGG CAAAGACTCT GTGATTGCTT TGCGCGAGCC TTCTTTGGGT


 


301
CCGGTGTTCG GCGTGAAAGG CGGCGCGGCA GGCGGCGGCT ATGCCCAAGT


 


351
TTTGCCGATG GAAGACATCA ACCTGCACTT CACCGGAGAT TTTCACGCCA


 


401
TCGGTGCGGC AAATAATCTG CTTGCCGCGA TGCTCGACAA CCATATCTAC


 


451
CAAGGCAACG AGTTGAACAT CGACCCCAAA CGCGTGCTGT GGCGGCGCGT


 


501
GGTCGATATG AACGACCGCC AGTTGCGCAA CATCATCGAC GGCATGGGCA


 


551
AGCCTGTTGA CGGCGTGATG CGTCCTGACG GTTTCGATAT TACCGTTGCT


 


601
TCCGAAGTGA TGGCGGTATT CTGTCTTGCC AAAGACATCA GCGATTTGAA


 


651
AGAGCGTTTG GGCAACATCC TTGTCGCCTA CGCCAAAGAC GGCAGCCCCG


 


701
TTTACGCCAA AGATTTGAAA GCGAATGGCG CGATGGCGGC ATTGCTTAAA


 


751
GATGCGATTA AGCCCAACTT GGTGCAAACC ATCGAAGGCA CGCCCGCCTT


 


801
CGTACACGGC GGCCCGTTCG CCAACATCGC CCACGGCTGC AACTCCGTAA


 


851
CCGCAACCCG TCTGGCGAAA CACCTTGCCG ATTACGCCGT AACCGAAGCA


 


901
GGCTTCGGCG CGGACTTGGG CGCGGAAAAA TTCTGCGACA TCAAATGCCG


 


951
CCTTGCCGGT TTGAAACCTG ATGCGGCTGT TGTCGTGGCG ACTGTCCGCG


 


1001
CGTTGAAATA TAACGGCGGC GTGGAACGCG CCAACCTCGG CGAAGAAAAT


 


1051
TTAGACGCTT TGGAAAAAGG TTTGCCCAAC CTGCTGAAAC ACATTTCCAA


 


1101
CCTGAAAAAC GTATTCGGAC TGCCCGTCGT CGTTGCGCTC AACCGCTTCG


 


1151
TGTCCGACTC CGATGCCGAG TTGGCGATGA TTGAAAAAGC CTGTGCCGAA


 


1201
CACGGCGTTG AAGTTTCCCT GACCGAAGTG TGGGGCAAAG GTGGTGCGGG


 


1251
CGGCGCGGAT TTGGCGCGCA AAGTCGTCAA CGCCATTGAA AGTCAAACCA


 


1301
ATAACTTCGG TTTCGCCTAC GATGTCGAGT TGGGCATCAA AGACAAAATC


 


1351
CGTGCGATTG CCCAAAAAGT GTACGGCGCG GAAGATGTTG ATTTCAGCGC


 


1401
GGAAGCGTCT GCCGAAATCG CTTCACTGGA AAAACTGGGC TTGGACAAAA


 


1451
TGCCGATCTG CATGGCGAAA ACCCAATACT CTTTGAGCGA CAACGCCAAA


 


1501
CTGTTGGGCT GCCCCGAAGA CTTCCGCATC GCCGTGCGCG GCATCACCGT


 


1551
TTCCGCAGGC GCAGGTTTCA TCGTCGCCCT GTGCGGCAAC ATGATGAAAA


 


1601
TGCCCGGCCT GCCCAAAGTT CCGGCTGCCG AGAAAATCGA TGTGGACGCA


 


1651
GAAGGCGTGA TTCACGGCTT GTTCTGA






This corresponds to the amino acid sequence <SEQ ID 558; ORF 141.a>:










a141.pep




1
MSFKTDAEIA QSSTMRPIGE IAAKLGLNVD NIEPYGHYKA KINPAEAFKL


 


51
PQKQGRLILV TAINPTPAGE GKTTVTIGLA DALRHIGKDS VIALREPSLG


 


101
PVFGVKGGAA GGGYAQVLPM EDINLHFTGD FHAIGAANNL LAAMLDNHIY


 


151
QGNELNIDPK RVLWRRVVDM NDRQLRNIID GMGKPVDGVM RPDGFDITVA


 


201
SEVMAVFCLA KDISDLKERL GNILVAYAKD GSPVYAKDLK ANGAMAALLK


 


251
DAIKPNLVQT IEGTPAFVHG GPFANIAHGC NSVTATRLAK HLADYAVTEA


 


301
GFGADLGAEK FCDIKCRLAG LKPDAAVVVA TVRALKYNGG VERANLGEEN


 


351
LDALEKGLPN LLKHISNLKN VFGLPVVVAL NRFVSDSDAE LAMIEKACAE


 


401
HGVEVSLTEV WGKGGAGGAD LARKVVNAIE SQTNNFGFAY DVELGIKDKI


 


451
RAIAQKVYGA EDVDFSAEAS AEIASLEKLG LDKMPICMAK TQYSLSDNAK


 


501
LLGCPEDFRI AVRGITVSAG AGFIVALCGN MMKMPGLPKV PAAEKIDVDA


 


551
EGVIHGLF*






m141/a141 99.5% identity in 558 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 559>:










g142.seq




1
ATGCGTGCCG ATTTCATGTT TGCCGACAAT ATGCCCGTGC AGGTGCGCCA


 


51
ACGCGCCTTC TATTTCAAGT TGTCCCGTTT TGCCGCGATG CCAAATATGG


 


101
TAGGCAAACC GCTCTTCGGG CGACAGGCCG GTCAGCCCGG CAAAATGTTC


 


151
GGCAACATCC TGATGTTCGT CCGCCAGCAT ATTGATGCAG AGgCTGCCGT


 


201
TTTCCGACAG GATcggaATG AttcgCGCAC TCCGGTTTAT GCACAGCATC


 


251
ACGGTCGGCG GCTCGTCGGT AACCGGCGCA ACCGCCGTCA TTGTAATGCC


 


301
GTAACGCCCT GCCGCACCGT CTGTCGTGAT GACATGAACG CCTGCCGCAC


 


351
AGGATGCCAT CGCATCACGG AACGAAGTTT GAAAAGTTTT CTGCAAATCC


 


401
GCCATTTTTC CCCTTTAAAC CGTCCCCTAT ATAAGAATGC TGCACACAAG


 


451
GCATCCCCCC ATGTGCAGCA GTTCTGA






This corresponds to the amino acid sequence <SEQ ID 560; ORF 142.ng>:










g142.pep




1
MRADFMFADN MPVQVRQRAF YFKLSRFAAM PNMVGKPLFG RQAGQPGKMF


 


51
GNILMFVRQH IDAEAAVFRQ DRNDSRTPVY AQHHGRRLVG NRRNRRHCNA


 


101
VTPCRTVCRD DMNACRTGCH RITERSLKSF LQIRHFSPLN RPLYKNAAHK


 


151
ASPHVQQF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 561>:










m142.seq




1
ATGCGTGCCG ATTTCATGTT TGCCGACAAT ATGCCCGTGC AGGTGCGCCA


 


51
ACGCGCCCTC TATTTCAAGT TGTCCCGTTT TGCCGCGATG CCAGATGTGG


 


101
TAGGCAAACC GCTCTTCGGG CGACAGGCCG GTCAGCCCGG CAAAATGTTC


 


151
GGCAACATCC TGATGTTCGT CCGCCAGCGT ATTGATGCAG AGGCTGCCGT


 


201
TTTCCGACAG GATCGGAATG ATTCGCGCAC TCCGGTTGAT GCACAGCATC


 


251
ACGGTCGGCG GCTCGTCGGT AACCGGCGCG ACCGCCGTCA TTGTAATGCC


 


301
GTAACGCCCT GCCGCACCGT CTGTCGTGAT GACATGAACG CCTGCCGCGC


 


351
AAGATGCCAT CGCATCACGG AACGAAGTTT GAAAATTTTT CTGCAAATCC


 


401
GCCATTTTTC CCCTTTAAAC TGTCCCCTAT ATAAGAATGC TGCACACAAG


 


451
GCATCCCCcC ATGTGCAGCA GTTTTGA






This corresponds to the amino acid sequence <SEQ ID 562; ORF 142>:










m142.pep




1
MRADFMFADN MPVQVRQRAL YFKLSRFAAM PDVVGKPLFG RQAGQPGKMF


 


51
GNILMFVRQR IDAEAAVFRQ DRNDSRTPVD AQHHGRRLVG NRRDRRHCNA


 


101
VTPCRTVCRD DMNACRARCH RITERSLKIF LQIRHFSPLN CPLYKNAAHK


 


151
ASPHVQQF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 142 shows 93.7% identity over a 158 aa overlap with a predicted ORF (ORF 142.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 563>:










a142.seq




1
ATGCGTGCCG ATTTCATGTT TGCCGACAAT ATGCCCGTGC AGGTGCGCCA


 


51
ACGCGCCCTC TATTTCAAGT TGTCCCGTTT TGCCGCGATG CCAGATGTGG


 


101
TAGGCAAACC GCTCTTCGGG CGACAGGCCG GTCAGCCCGG CAAAATGTTC


 


151
GGCAACATCC TGATGTTCGT CCGCCAGCGT ATTGATGCAG AGGCTGCCGT


 


201
TTTCCGACAG GATCGGAATG ATTCGCGCAC TCCGGTTGAT GCACAGCATC


 


251
ACGGTCGGCG GCTCGTCCGT AACCGGCGCA ACCGCCGTCA TTGTAATGCC


 


301
GTAACGCCCT GCCGCACCGT CTGTCGTGAT GACATGAACG CCTGCCGCAC


 


351
AGGATGCCAT CGCATCACGG AACGAAGTTT GAAAAGTTTT CTGCAAATCC


 


401
GCCATTTTTC CCCTTTAAAC TGTCCCCTAT ATAAGAATGC TGCACACAAG


 


451
GCACCCCCCA TGTGCAGCAG TTCTGATTCA AAAAGCCGTC GGTCGGACAT


 


501
TTCCGCGCGT TACGGCGTAT TACGAGTTCA ACGCATCCTC GATTTTGGCA


 


551
AGTTCTGCCA ACAGGTCTTT AAGCAGCAGC ATTTTCTCGC GGCCCAGCAC


 


601
TTCCTCGATA GCGTCGTAAC GCTCGTCCAC TTCTTCGCCG ATTTCCTCAT


 


651
ACAGCTTCTC GCCCTCGGCA GTCAGCTTCA GAAAAACACG TCGTTGGTCG


 


701
TTGGAAGGTT TCAGGCGGAC AACCAAACCC GCTTTTTCAA GGCGGGTCAG


 


751
GATACCGGTC AGGCTGGGGC GCAAAATGCA CGCCTGATTC GCCAAATCTT


 


801
GAAAGTCCAG CGTGCCGTTT TCCGCCAAAA GACGGATAAT CCGCCATTGC


 


851
TGATCGGTAA TATTCGCCTG ATTCAGAATA GGCCTGAATT GGGTCATCAG


 


901
GGCTTCCCTT GCCTGTATCA GACCGATATT GATAGACGCA TGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 564; ORF 142.a>:










a142.pep




1
MRADFMFADN MPVQVRQRAL YFKLSRFAAM PDVVGKPLFG RQAGQPGKMF


 


51
GNILMFVRQR IDAEAAVFRQ DRNDSRTPVD AQHHGRRLVR NRRNRRHCNA


 


101
VTPCRTVCRD DMNACRTGCH RITERSLKSF LQIRHFSPLN CPLYKNAAHK


 


151
APPMCSSSDS KSRRSDISAR YGVLRVQRIL DFGKFCQQVF KQQHFLAAQH


 


201
FLDSVVTLVH FFADFLIQLL ALGSQLQKNT SLVVGRFQAD NQTRFFKAGQ


 


251
DTGQAGAQNA RLIRQILKVQ RAVFRQKTDN PPLLIGNIRL IQNRPELGHQ


 


301
GFPCLYQTDI DRRMF*






m142/a142 96.1% identity in 153 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 565>:










g143.seq




1
ATGTTGAGCT TCGGCTATCT CGGCGTTCAG ACGGCCTTTA CCCTGCAAAG


 


51
CTCGCAGATG AGCCGCATTT TTCAAACGCT AGGCGCAGAC CCGCACAATT


 


101
TGGGCTGGTT TTTCATCCTG CCGCCGCTGG CGGGGATGCT GGTTCAGCCG


 


151
ATAGTGgGCT ACTACTCAGA CCGCACTTGG AAGCCGCGCT TGGGCGGCCG


 


201
CCGCCTGCCG TATCTGCTTT ACGGCACGCT GATTGCGGTC ATCGTGATGA


 


251
TTTTGATGCC GAACTCGGGC AGCTTCGGTT TCGGCTATGC GTCGCTGGCG


 


301
GCCTTGTCGT TCGGCGCGCT GATGATTGCG CTGTTGGACG TGTCGTCGAA


 


351
TATGGCGATG CAGCCGTTTA AGATGATGGT CGGCGATATG GTCAACGAGG


 


401
AGCAGAAAAG CTACGCCTAC GGGATTCAAA GTTTCTTAGC GAATACGGAC


 


451
GCGGTTGTGG CAGCGATTCT GCCGTTTGTG TTcgcgtata TCGGTTTGGC


 


501
GAACACTGCC GAGAAAGGCG TTGTGCCACA AACCGTGGTC GTAGCATTCT


 


551
ATGTGGGTGC GGCGTTACTG ATTATTACCA GTGCGTTCAC AATCTCCAAA


 


601
GTCAAAGAAT ACGACCCGGA AACCTACGCC CGTTACCACG GCATCGATGT


 


651
CGCCGCGAAT CAGGAAAAAG CCAACTGGTT CGAACTCTTA AAAACCGCGC


 


701
CTAAAGTGTT TTGGACGGTT ACTCCGGTAC AGTTTTTCTG CTGGTTCGCC


 


751
TTCCGGTATA TGTGGACTTA CTCGGCAGGC GCGATTGCAG AAAACGTCTG


 


801
GCACACTACC GATGCGTCTT CCGTAGGCCA TCAGGAGGCG GGCAACCGGT


 


851
ACGGCGTTTT GGCGGCGGTG TAGTCGGTTG CGGCGGTGAT TTGTTCGTTT


 


901
ATTCTGGCAA AAGTACCGAA TAAATACCAT AAGGCGGGTT ATTTCGGCTG


 


951
TTTGGCTTTG GGCGCGCTCG GTTTCTTCTC TATCTTCTTC ATCTACAATC


 


1001
AATACGCACT CATCCTGTCT TATATCTTAA TCGGCATCGC TTGGGCGGGC


 


1051
ATTATCACTT ATCCGCTGAC GATTGTGGCC AACGCTTTGT CGGGCAAACA


 


1101
CATGGATACT TATTTGGGCC TGTttaacgg ctctgtCTGT ATGCcgcaaa


 


1151
tcgTcgctTC GctgttgAGT TTCGTGCTTT TCCCGATGCT GGGCGGCCAT


 


1201
CAGGCAACCA TGTTCTTGGT TGCAGGCGCA GTCTTGCTGC TGGGAGCCTT


 


1251
CTCAGTCTGT CTGATTAAAG AGATCCACGG CGGGGTTTGA






This corresponds to the amino acid sequence <SEQ ID 566; ORF 143.ng>:










g143.pep




1
MLSFGYLGVQ TAFTLQSSQM SRIFQTLGAD PHNLGWFFIL PPLAGMLVQP


 


51
IVGYYSDRTW KPRLGGRRLP YLLYGTLIAV IVMILMPNSG SFGFGYASLA


 


101
ALSFGALMIA LLDVSSNMAM QPFKMMVGDM VNEEQKSYAY GIQSFLANTD


 


151
AVVAAILPFV FAYIGLANTA EKGVVPQTVV VAFYVGAALL IITSAFTISK


 


201
VKEYDPETYA RYHGIDVAAN QEKANWFELL KTAPKVFWTV TPVQFFCWFA


 


251
FRYMWTYSAG AIAENVWHTT DASSVGHQEA GNRYGVLAAV *SVAAVICSF


 


301
ILAKVPNKYH KAGYFGCLAL GALGFFSIFF IYNQYALILS YILIGIAWAG


 


351
IITYPLTIVA NALSGKHMDT YLGLFNGSVC MPQIVASLLS FVLFPMLGGH


 


401
QATMFLVAGA VLLLGAFSVC LIKEIHGGV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 567>:










m143.seq




1
ATGCTCAGTT TCGGCTTTCT CGGCGTTCAG ACGGCCTTTA CCCTGCAAAG


 


51
CTCGCAAATG AGCCGCATTT TTCAAACGCT AGGCGCAGAC CCGCACAATT


 


101
TGGGCTGGTT TTTCATCCTG CCGCCGCTGG CGGGGATGCT GGTGCAGCCG


 


151
ATTGTCGGCC ATTACTCCGA CCGCACTTGG AAGCCGCGTT TGGGCGGCCG


 


201
CCGTCTGCCG TATCTGCTTT ATGGCACGCT GATTGCGGTT ATTGTGATGA


 


251
TTTTGATGCC GAACTCGGGC AGCTTCGGTT TCGGCTATGC GTCGCTGGCG


 


301
GCTTTGTCGT TCGGCGCGCT GATGATTGCG CTGTTAGACG TGTCGTCAAA


 


351
TATGGCGATG CAGCCGTTTA AGATGATGGT CGGCGACATG GTCAACGAGG


 


401
AGCAGAAAGG CTACGCCTAC GGGATTCAAA GTTTCTTAGC AAATACGGGC


 


451
GCGGTCGTGG CGGCGATTCT GCCGTTTGTG TTTGCGTATA TCGGTTTGGC


 


501
GAACACCGCC GAGAAAGGCG TTGTGCCGCA GACCGTGGTC GTGGCGTTTT


 


551
ATGTGGGTGC GGCGTTGCTG GTGATTACCA GCGCGTTCAC GATTTTCAAA


 


601
GTGAAGGAAT ACGATCCGGA AACCTACGCC CGTTACCACG GCATCGATGT


 


651
CGCCGCGAAT CAGGAAAAAG CCAACTGGAT CGAACTCTTG AAAACCGCGC


 


701
CTAAGGCGTT TTGGACGGTT ACTTTGGTGC AATTCTTCTG CTGGTTCGCC


 


751
TTCCAATATA TGTGGACTTA CTCGGCAGGC GCGATTGCGG AAAACGTCTG


 


801
GCACACCACC GATGCGTCTT CCGTAGGTTA TCAGGAGGCG GGTAACTGGT


 


851
ACGGCGTTTT GGCGGCGGTG CAGTCGGTTG CGGCGGTGAT TTGTTCGTTT


 


901
GTATTGGCGA AAGTGCCGAA TAAATACCAT AAGGCGGGTT ATTTCGGCTG


 


951
TTTGGCTTTG GGCGCGCTCG GCTTTTTCTC CGTTTTCTTC ATCGGCAACC


 


1001
AATACGCGCT GGTGTTGTCT TATACCTTAA TCGGCATCGC TTGGGCGGGC


 


1051
ATTATCACTT ATCCGCTGAC GATTGTGACC AACGCCTTGT CGGGCAAGCA


 


1101
TATGGGCACT TACTTGGGCT TGTTTAACGG CTCTATCTGT ATGCCTCAAA


 


1151
TCGTCGCTTC GCTGTTGAGT TTCGTGCTTT TCCCTATGCT GGGCGGCTTG


 


1201
CAGGCCACTA TGTTCTTGGT AGGGGGCGTC GTCCTGCTGC TGGGCGCGTT


 


1251
TTCCGTGTTC CTGATTAAAG AAACACACGG CGGGGTTTGA






This corresponds to the amino acid sequence <SEQ ID 568; ORF 143>:










m143.pep




1
MLSFGFLGVQ TAFTLQSSQM SRIFQTLGAD PHNLGWFFIL PPLAGMLVQP


 


51
IVGHYSDRTW KPRLGGRRLP YLLYGTLIAV IVMILMPNSG SFGFGYASLA


 


101
ALSFGALMIA LLDVSSNMAM QPFKMMVGDM VNEEQKGYAY GIQSFLANTG


 


151
AVVAAILPFV FAYIGLANTA EKGVVPQTVV VAFYVGAALL VITSAFTIFK


 


201
VKEYDPETYA RYHGIDVAAN QEKANWIELL KTAPKAFWTV TLVQFFCWFA


 


251
FQYMWTYSAG AIAENVWHTT DASSVGYQEA GNWYGVLAAV QSVAAVICSF


 


301
VLAKVPNKYH KAGYFGCLAL GALGFFSVFF IGNQYALVLS YTLIGIAWAG


 


351
IITYPLTIVT NALSGKHMGT YLGLFNGSIC MPQIVASLLS FVLFPMLGGL


 


401
QATMFLVGGV VLLLGAFSVF LIKETHGGV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m143/g143 93.9% identity in 429 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 569>:










a143.seq




1
ATGCTCAGTT TCGGCTTTCT CGGCGTTCAG ACGGCCTTTA CCCTGCAAAG


 


51
CTCGCAGATG AGCCGCATCT TCCAGACGCT CGGTGCCGAT CCGCACAGCC


 


101
TCGGCTGGTT CTTTATCCTG CCGCCGCTGG CGGGGATGCT GGTGCAGCCG


 


151
ATTGTCGGCC ATTACTCCGA CCGCACTTGG AAGCCGCGTT TGGGCGGCCG


 


201
CCGTCTGCCG TATCTGCTTT ATGGCACGCT GATTGCGGTT ATTGTGATGA


 


251
TTTTGATGCC GAACTCGGGC AGCTTCGGTT TCGGCTATGC GTCGCTGGCG


 


301
GCTTTGTCGT TCGGCGCGCT GATGATTGCG CTGTTAGACG TGTCGTCAAA


 


351
TATGGCGATG CAGCCGTTTA AGATGATGGT CGGCGACATG GTCAACGAGG


 


401
AGCAGAAAGG CTACGCCTAC GGGATTCAAA GTTTCTTAGC GAATACGGGC


 


451
GCGGTCGTGG CGGCGATTCT GCCGTTTGTG TTTGCGTATA TCGGTTTGGC


 


501
GAACACCGCC GAGAAAGGCG TTGTGCCGCA GACCGTGGTC GTGGCGTTTT


 


551
ATGTGGGTGC GGCGTTGCTG GTGATTACCA GCGCGTTCAC GATTTTCAAA


 


601
GTGAAGGAAT ACAATCCGGA AACCTACGCC CGTTACCACG GCATCGATGT


 


651
CGCCGCGAAT CAGGAAAAAG CCAACTGGAT CGAACTCTTG AAAACCGCGC


 


701
CTAAGGCGTT TTGGACGGTT ACTTTGGTGC AATTCTTCTG CTGGTTCGCC


 


751
TTCCAATATA TGTGGACTTA CTCGGCAGGC GCGATTGCGG AAAACGTCTG


 


801
GCACACCACC GATGCGTCTT CCGTAGGTTA TCAGGAGGCG GGTAACTGGT


 


851
ACGGCGTTTT GGCGGCGGTG CAGTCGGTTG CGGCGGTGAT TTGTTCGTTT


 


901
GTATTGGCGA AAGTGCCGAA TAAATACCAT AAGGCGGGTT ATTTCGGCTG


 


951
TTTGGCTTTG GGCGCGCTCG GCTTTTTCTC CGTTTTCTTC ATCGGCAACC


 


1001
AATACGCGCT GGTGTTGTCT TATACCTTAA TCGGCATCGC TTGGGCGGGC


 


1051
ATTATCACTT ATCCGCTGAC GATTGTGACC AACGCCTTGT CGGGCAAGCA


 


1101
TATGGGCACT TACTTGGGCC TGTTTAACGG CTCTATCTGT ATGCCGCAAA


 


1151
TCGTCGCTTC GCTGTTGAGT TTCGTGCTTT TCCCTATGCT GGGCGGCTTG


 


1201
CAGGCCACTA TGTTCTTGGT AGGGGGCGTC GTCCTGCTGC TGGGCGCGTT


 


1251
TTCCGTGTTC CTGATTAAAG AAACACACGG CGGGGTTTGA






This corresponds to the amino acid sequence <SEQ ID 570; ORF 143.a>:










a143.pep




1
MLSFGFLGVQ TAFTLQSSQM SRIFQTLGAD PHSLGWFFIL PPLAGMLVQP


 


51
IVGHYSDRTW KPRLGGRRLP YLLYGTLIAV IVMILMPNSG SFGFGYASLA


 


101
ALSFGALMIA LLDVSSNMAM QPFKMMVGDM VNEEQKGYAY GIQSFLANTG


 


151
AVVAAILPFV FAYIGLANTA EKGVVPQTVV VAFYVGAALL VITSAFTIFK


 


201
VKEYNPETYA RYHGIDVAAN QEKANWIELL KTAPKAFWTV TLVQFFCWFA


 


251
FQYMWTYSAG AIAENVWHTT DASSVGYQEA GNWYGVLAAV QSVAAVICSF


 


301
VLAKVPNKYH KAGYFGCLAL GALGFFSVFF IGNQYALVLS YTLIGIAWAG


 


351
IITYPLTIVT NALSGKHMGT YLGLFNGSIC MPQIVASLLS FVLFPMLGGL


 


401
QATMFLVGGV VLLLGAFSVF LIKETHGGV*






m143/a143 99.5% identity in 429 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 571>:










g144.seq




1
ATGAGCGATA CCCCCGCTAC CCGCGATTTC GGCCTGATCG ACGGGCGGGC


 


51
CGTAACCGGC TATGTGCTGT CCAACCGGCG TGGTACGTGC GTCTTCGTGC


 


101
TGGACTTGGG CGGGATTGTG CAGGAATTTT CCGTTTTGGC AGACGGCGTG


 


151
CGCGAAAACC CCGTGGTGTC GTTCGACGAT GCGGCTTCCT ATGCGGACAA


 


201
TCCGTTTCAG ATTAACAAGC AGATAGGGCG CGTGGCCGGA CGCATCCGCG


 


251
GTGCGGCGTT CGACATCAAC GGTAGGACTT ACCGCGTGGA GGCCAACGAA


 


301
GGCAGGAACG CGCTGCACGG CGGTTCGCAC GGGCTGGCCG TTACCcgtTT


 


351
CAACGCGGTG GCGGCAGACG GccgacggTt atCCCAACGA TTTGGatatT


 


401
TCctaccgCT TGGACGAGGA CGGCCGGCTT ACCGTtaccT ATCGCGCCAC


 


451
CGCgctCGGC GACACGGTGT TCGACCCGAC GCTGCACATT TACTGGCGGC


 


501
TGGACGCGGG CCTGCACGAT GCGGTTCTGC ATATTCCGCA GGGCGGACAT


 


551
ATTCCGGCCG ATGCCGAAAA ACTGCCCGTC TTAACGGTTT CAGACGGCCT


 


601
CGAAGTATTT GA






This corresponds to the amino acid sequence <SEQ ID 572; ORF 144.ng>:










g144.pep




1
MSDTPATRDF GLIDGRAVTG YVLSNRRGTC VFVLDLGGIV QEFSVLADGV


 


51
RENPVVSFDD AASYADNPFQ INKQIGRVAG RIRGAAFDIN GRTYRVEANE


 


101
GRNALHGGSH GLAVTRFNAV AADGRRLSQR FGYFLPLGRG RPAYRYLSRH


 


151
PARRHGVRPD AAHLLAAGRG PARCGSAYSA GRTYSGRCRK TARLNGFRRP


 


201
RSI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 573>:










m144.seq




1
ATGAGCGATA CCCCCGCTAC CCGCGATTTC GGTCTGATCG ACGGGCGTGC


 


51
CGTAACCGGC TATGTGCTGT CCAACCGGCG TGGTACGCGT GTCTGCGTGC


 


101
TGGACTTGGG CGGGATTGTG CAGGAATTTT CCGTTTTGGC AGACGGCGTG


 


151
CGCGAAAACC TCGTGGTGTC GTTCGATGAT GCGGCTTCCT ATGCGGACAA


 


201
TCCGTTTCAG ATTAACAAAC AGATAGGGCG CGTGGCCGGA CGCATCCGCG


 


251
GTGCGGCGTT CGACATCAAC GGCAGGACTT ACCGCGTGGA GGCCAACGAA


 


301
GGCAGGAACG CGCTGCACGG CGGTTCGCAC GGGCTGGCCG TTACCCGTTT


 


351
CAACGCGGTG GCGGCAGACG GCCGTTCGGT GGTGCTGCGC AGCCGCCTGg


 


401
CAACAGTCGG CCGACGGTTA TCCCAACGAT TTGGATTTGG ATATTTCCTA


 


451
CCGCTTGGAC GAGGACGACC GGCTTACCGT TAcCTATCGC GCCACCGCGC


 


501
TCGGCGACAC GGTGTTCGAC CCGACGCTGC ACATTTACTG GCGGCTGGAC


 


551
GCGGGCCTGC ACGATGCGGT TCTGCATATT CCGCAGGGCG GACATATGCC


 


601
GGCCGATGCC GAAAAACTGC CCGTCTCAAC GGTTTCAGAC GACCTCGAAG


 


651
TATTTGA






This corresponds to the amino acid sequence <SEQ ID 574; ORF 144>:










m144.pep




1
MSDTPATRDF GLIDGRAVTG YVLSNRRGTR VCVLDLGGIV QEFSVLADGV


 


51
RENLVVSFDD AASYADNPFQ INKQIGRVAG RIRGAAFDIN GRTYRVEANE


 


101
GRNALHGGSH GLAVTRFNAV AADGRSVVLR SRLATVGRRL SQRFGFGYFL


 


151
PLGRGRPAYR YLSRHRARRH GVRPDAAHLL AAGRGPARCG SAYSAGRTYA


 


201
GRCRKTARLN GFRRPRSI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m144/g144 91.3% identity in 218 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 575>:










a144.seq




1
ATGAGCGATA CCCCCGCTAC CCGCGATTTC GGCCTGATCG ACGGGCGTGC


 


51
CGTAACCGGC TATGTGCTGT CCAACCGGCG TGGTACGCGT GTCTGCGTGC


 


101
TGGACTTGGG CGGGATTGTG CAGGAATTTT CCGTTTTGGC AGACGGCGTG


 


151
CGCGAAAACC TCGTGGTGTC GTTCGACGAT GCGGCTTCCT ATGCGGACAA


 


201
TCCGTTTCAG ATTAACAAGC AGATAGGGCG CGTGGCCGGA CGCATCCGCG


 


251
GTGCGGCGTT CGACATCAAC GGCAGGACTT ACCGCGTGGA GGCCAACGAA


 


301
GGCAGGAACG CGCTGCACGG CGGTTCGCAC GGGCTGGCCG TTACCCGTTT


 


351
CAACGCGGTG GCGGCAGACG GCCGTTCGGT GGTGCTGCGC AGCCGCCTG.


 


401
CAACAGTCGG CCGACGGTTA TCCCAACGAT TTGGATTTGG ATATTTCCTA


 


451
CCGCTTGGAC GAGGACGACC GGCTTACCGT TACCTATCGC GCCACCGCGC


 


501
TCGGCGACAC GGTGTTCGAC CCGACGCTGC ACATTTACTG GCGGCTGGAC


 


551
GCGGGCCTGC ACGATGCGGT TCTGCATATT CCGCAGGGCG GACATATTCC


 


601
GGCCGATGCC GAAAAACTGC CCGTCTCAAC GGTTTCAGAC GACCTCGAAG


 


651
TATTTGA






This corresponds to the amino acid sequence <SEQ ID 576; ORF 144.a>:










a144.pep




1
MSDTPATRDF GLIDGRAVTG YVLSNRRGTR VCVLDLGGIV QEFSVLADGV


 


51
RENLVVSFDD AASYADNPFQ INKQIGRVAG RIRGAAFDIN GRTYRVEANE


 


101
GRNALHGGSH GLAVTRFNAV AADGRSVVLR SRLXTVGRRL SQRFGFGYFL


 


151
PLGRGRPAYR YLSRHRARRH GVRPDAAHLL AAGRGPARCG SAYSAGRTYS


 


201
GRCRKTARLN GFRRPRSI*






m144/a144 99.1% identity in 218 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 577>:










g146.seq




1
ATGAAGCAAA TCCCCCTCCG CCTTCTCCAG GTCGTCATTG ACCACGACAA


 


51
AGTCGAACAA TACGGACTGT TCGATTTCAT GCCTTGCCTT CGACAGCCTC


 


101
CTTTGGATAa ctTCCCGACT GTCCGTCCCG CGCcctTTGA GGCGCGCGGC


 


151
AAGCACGTCG AAAGAAGGCG GCAGGATAAA GATACCGACA GCTTCCGGCA


 


201
GCGCGTTGCG AACCTGCGCC GCGCCCTGAA CGTCGATTTC CAAAATCACG


 


251
TCATAGCCTG CCGCCGCCAA CGCATTCACG CCCTCCGTGC TTGTGCCGTA


 


301
ATAGTTGCCG AATACGTCTG CGTATTCCAA AAAAGCCTCC TGCGCGATAA


 


351
GCGATTCAAA CTCTTCTTTG GAAACAAAGT GATAATGTAC GCCGTTTGCT


 


401
TCGCCTTCAC GCGGCGGGCG CGTCGTATGC GACACGGAAA CGCGCAAACC


 


451
GTTATGGTTT GCCAACAGCC GCGACACCAG CGTGGTTTTG CCCGTGCCGG


 


501
AAGCGGCCGA AATGATAAAG ATGTTGCCTT TTCGATAAGC GGACATATTT


 


551
TTTACCTGTA TATTTTCCAA CCGATTGTAT CACAACGGAC ACCCTATTTC


 


601
ATATTTGCCG ATGCCCATAT TTTGCCGCTA TTGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 578; ORF 146.ng>:










g146.pep




1
MKQIPLRLLQ VVIDHDKVEQ YGLFDFMPCL RQPPLDNFPT VRPAPFEARG


 


51
KHVERRRQDK DTDSFRQRVA NLRRALNVDF QNHVIACRRQ RIHALRACAV


 


101
IVAEYVCVFQ KSLLRDKRFK LFFGNKVIMY AVCFAFTRRA RRMRHGNAQT


 


151
VMVCQQPRHQ RGFARAGSGR NDKDVAFSIS GHIFYLYIFQ PIVSQRTPYF


 


201
IFADAHILPL LF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 579>:










m146.seq




1
ATGGCGCAAA TCCTCCTCCG CTCGCGCCAA GTCGTCATTG ACCACGACAA


 


51
AGTCAAACAA TACGGACTGC TCGATTTCAT GCCTTGCCTT CGACAGCCTC


 


101
CTTTGGATAA CTTCCCGACT GTCCGTCCCG CGTCCGTTGA GGCGCGCGGC


 


151
AAGTACGTCG AAAGAAGGCG GCAGGATAAA GATGCCGACG GCTTCGGGCA


 


201
GCGCGTCGCG AACCTGCGCC GCGCCCTGAA CGTCGATTTC CAAAATCACG


 


251
TCATAGCCTG CCGCCGCCAA CGCATTCACA CCCTCCGCGC CTGTGCCGTA


 


301
ATAGTTGCCA AATACGTCGG CGTATTCCAA AAAAGCTTCC TGCGCGATAA


 


351
GCGACTCAAA CTCTTCTTTG GAAACAAAGT GATAATGTAC GCCGTTTGCT


 


401
TCGCCTTCAC GCGGCGGGCG CGTCGTGTGC GACACGGAAA CGCGCAAACC


 


451
GTTATGGTTT GCCAACAGCC GCGACACCAG CGTGGTTTTG CCCGTGCCGG


 


501
AAGCGGCCGA AATGATAAAG ATGTTGCCTT TTCGATAAGC GGACATATTT


 


551
TTTACCTGTA TATTTTCCAG CCGATTGTAT CACAATGGAC ACCCAGTTTC


 


601
CTATTTGCCG ATGCCCATAT TTTGCCGCTA TTGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 580; ORF 146>:










m146.pep




1
MAQILLRSRQ VVIDHDKVKQ YGLLDFMPCL RQPPLDNFPT VRPASVEARG


 


51
KYVERRRQDK DADGFGQRVA NLRRALNVDF QNHVIACRRQ RIHTLRACAV


 


101
IVAKYVGVFQ KSFLRDKRLK LFFGNKVIMY AVCFAFTRRA RRVRHGNAQT


 


151
VMVCQQPRHQ RGFARAGSGR NDKDVAFSIS GHIFYLYIFQ PIVSQWTPSF


 


201
LFADAHILPL LF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m146/g146 90.1% identity in 212 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 581>:










a146.seq




1
ATGGCGCAAA TCCTCCTCCG CCCGCGCCAA GTCATCATTG ACCACGACAA


 


51
AATCGAACAA TACGGACTGT TCGATTTCAT GCCTTGCCTT CGACAGCCTC


 


101
CTTTGGATAA CTTCCCGACT GTCCGTCCCG CGTCCGTTGA GACGCGCAGC


 


151
AAGCACATCG AAAGACGGCG GCAGGATAAA GATGCCGACG GCTTCGGGCA


 


201
GCGCATCTCG AACCTGAGCC GCGCCCTGAA CGTCGATTTC CAAAATCACG


 


251
TCATAACCTG CCGCCGCCAA CGCATTCACA CCCTCCGCGC TTGTGCCGTA


 


301
ATAGTTGCCG AACACGTCCG CGTATTCCAA AAAAGCCTCC TGCGCGATAA


 


351
GCGACTCAAA CTCTTCTTTG GAAACAAAGT GATAATGTAC GCCGTTTGCT


 


401
TCGCCTTCAC GCGGCGGACG CGTCGTGTGC GACACGGAAA CGCGCAAACC


 


451
GTTATGGTTT GCCAACAGCC GCGACACCAG CGTGGTTTTG CCCGTGCCGG


 


501
AAGCGGCCGA AATGATAAAG ATGTTGCCTT TTCGATAAGC GGACATATTT


 


551
TTTACCTGTA TATTTTCCAG CCGATTGTAT CACAACGGAC ACCCGGTTTC


 


601
CTATTTGCCG ATGCCCATAT TTTGCCGCTA TTGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 582; ORF 146.a>:










a146.pep




1
MAQILLRPRQ VIIDHDKIEQ YGLFDFMPCL RQPPLDNFPT VRPASVETRS


 


51
KHIERRRQDK DADGFGQRIS NLSRALNVDF QNHVITCRRQ RIHTLRACAV


 


101
IVAEHVRVFQ KSLLRDKRLK LFFGNKVIMY AVCFAFTRRT RRVRHGNAQT


 


151
VMVCQQPRHQ RGFARAGSGR NDKDVAFSIS GHIFYLYIFQ PIVSQRTPGF


 


201
LFADAHILPL LF*






m146/a146 90.6% identity in 212 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 583>:









g147.seq (partial)










1
..ATGCGACGAG AAGCCAAAAT GGCACAAATC ACACTCAAAC CCATTGTTTT



 


51
  ATCAATTCTT TTAATCAACA CACCCCTCCT CGCCCAAGCG CATGAAACTG


 


101
  AGCAATCGGT GGGCTTGGAA ACGGTCAGCG TCGTCGGCAA AAGCCGTCCG


 


151
  CGCGCGACTT CGGGGCTGCT GCACACTTCG ACCGCCTCCG ACAAAATCAT


 


201
  CTCCGGCGAT ACTTTGCGCC AAAAAGCCGT CAACTTGGGC GACGCTTTGG


 


251
  ACGGCGTACC GGGCATCCAC GCTTCGCAAT ACGGCGGCGG CGCATCCGCT


 


301
  CCCGTTATTC GCGGTCAAAC GGGCAGACGG ATTAAAGTAT TGAACCATCA


 


351
  CGGCGAAACG GGCGATATGG CGGACTTTTC TCCCGATCAC GCCATTATGG


 


401
  TAGATACCGC CTTGTCGCAA CAGGTTGAAA TCCTGCGCGG GCCGGTTACG


 


451
  CTCTTGTACA GCTCGGgcaa tgtggccgGG GCTGGtcaat gttgccgatg


 


501
  gAAAAAtccc ccaaaaAAtg cc..






This corresponds to the amino acid sequence <SEQ ID 584; ORF 147.ng>:









g147.pep (partial)










1
..MRREAKMAQI TLKPIVLSIL LINTPLLAQA HETEQSVGLE TVSVVGKSRP



 


51
  RATSGLLHTS TASDKIISGD TLRQKAVNLG DALDGVPGIH ASQYGGGASA


 


101
  PVIRGQTGRR IKVLNHHGET GDMADFSPDH AIMVDTALSQ QVEILRGPVT


 


151
  LLYSSGNVAG AGQCCRWKNP PKNA..






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 585>:









m147.seq (partial)










1
..CCGCATAAAA CTGAGCAATC GGTGGATTTG GAAACGGTCA GCGTCGTCGG



 


51
  CAAAAGCCGT CCGCGCGCCA CGTCGGGGCT GTTGCACACT TCGACCGCCT


 


101
  CCGACAAAAT CATCTCCGGC GATACCTTGC GCCAAAAAGC CGTCAACTTG


 


151
  GGCGACGCTT TAGACGGCGT ACCGGGCATC CACGCTTCGC AATACGGCGG


 


201
  CGGCGCGTCT GCTCCCGTCA TTCGCGGTCA AACAGGCAGG CGGATTAAAG


 


251
  TGTTGAACCA TCACGGCGAA ACAGGCGATA TGGCGGATTT TTCGCCCGAT


 


301
  CACGCCATTA TGGTAGATAC CGCCTTGTCG CAACAGGTCG AAATCCTGCG


 


351
  CGGGCCGGTT ACGCTCTTGT ACAGCTCGGG CAATGTGGCG GGGCTGGTCG


 


401
  ATGTTGCCGA TGGCAAAATC CCCGAAAAAA TGCCTGAAAA CGGCGTATCG


 


451
  GGCGAACTCG GATTGCGTTT GAGCAGCGGC AATCTGGAAA AACTCACGTC


 


501
  CGGCGGCATC AATATCGGTT TGGGCAAAAA CTTTGTATTG CACACGGAAG


 


551
  GGCTGTACCG CAAATCGGGG GATTACGCCG TACCGCGTTA CCGCAATCTG


 


601
  AAACGCCTGC CCGACAGCCA CGCCGATTCG CAAACGGGCA GCATCGGGCT


 


651
  GTCTTGGGTT GGCGAAAAAG GTTTTATCGG CGTAGCGTAC AGCGACCGTC


 


701
  GCGACCAATA TGGTCTGCCT GCCCACAGCC ACGAATACGA TGATTGCCAC


 


751
  GCCGACATCA TCTGGCAAAA GAGCTTGATT AACAAACGCT ATTTACAGCT


 


801
  TTATCCGCAC CTGTTGACCG AAGAAGACAT CGATTACGAC AATCCGGGCT


 


851
  TGAGCTGCGG CTTCCACGAC GACGATAATG CACACGCACA CACCCACAGC


 


901
  GGCAGACCGT GGATAGACCT GCGCAACAAA CGCTACGAAC TCCGTGCCGA


 


951
  ATGGAAGCAA CCGTTCCCCG GTTTTGAAGC CCTGCGCGTA CACCTGAACC


 


1001
  GCAACGACTA CCGCCACGAC GAAAAAGCAG GCGATGCAGT CGAAAACTTT


 


1051
  TTTAACAACC AAACGCAAAA CGGCGGCATC GAGTTGCGCC ACCAACCCAT


 


1101
  AGGTCGTCTG AAAGGCAGCT GGGGCGTGCA ATATTTACAA CAAAAATCCA


 


1151
  GTGCTTTATC TGCCATATCC GAAGCGGTTA AACAACCGAT GCTGCTTGAC


 


1201
  AACAAAGTGC AACATTACAG CTTTTTCGGT GTAGAACAGG CAAACTGGGA


 


1251
  CAACTTCACG CTTGAAGGAG GCGTACGCGT GGAAAAACAA AAAGCCTCCA


 


1301
  TTCAGTACGA CAAAGCATTG ATTGATCGGG AAAACTACTA CAACCACCCC


 


1351
  CTGCCCGACC TCGGCGCGCA CCGCCAAACC GCCCGCTCAT TCGCACTTTC


 


1401
  GGGCAACTGG TATTTCACGC CACAACACAA ACTCAGCCTG ACCGCCTCCC


 


1451
  ATCAGGAACG CCTGCCGTCA ACGCAAGAGC TGTACGCACA CGGCAAACAC


 


1501
  GTCGCCACCA ACACCTTTGA AGTCGGCAAC AAACACCTCA ACAAAGAGCG


 


1551
  TTCCAACAAT ATCGAACTCG CGCTGGGCTA CGAAGGCGAC CGCTGGCAAT


 


1601
  ACAATCTGGC ACTCTACCGC AACCGCTTCG GTAACTACAT TTACGCCCAA


 


1651
  ACCTTAAACG ACGGACGCGG CCCCAAATCC ATCGAAGACG ACAGCGAAAT


 


1701
  GAAGCTCGTG CGCTACAACC AATCCGGCGC CGACTTCTAC GGCGCGGAAG


 


1751
  GCGAAATCTA CTTCAAACCG ACACCGCGCT ACCGCATCGG CGTTTCCGGC


 


1801
  GACTATGTAC GAGGCCGTCT GAAAAACCTG CCTTCCCTAC CCGGCAGAGA


 


1851
  AGATGCCTAC GGCAACCGTC CTTTCATCGC ACAGGACGAC CAAAATGCCC


 


1901
  CCCGTGTTCC GGCTGCGCGC CTCGGCTTCC ACCTGAAAGC CTCGCTGACC


 


1951
  GACCGTATCG ATGCCAATTT GGACTACTAC CGCGTGTTCG CCCAAAACAA


 


2001
  ACTCGCCCGC TACGAAACGC GCACGCCCGG ACACCATATG CTCAACCTCG


 


2051
  GCGCAAACTA CCGCCGCAAT ACGCGCTATG GCGAGTGGAA TTGGTACGTC


 


2101
  AAAGCCGACA ACCTGCTCAA CCAATCCGTT TACGCCCACA GCAGCTTTCT


 


2151
  CTCTGATACG CCGCAAATGG GCCGCAGCTT TACCGGCGGC GTGAACGTGA


 


2201
  AGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 586; ORF 147>:









m147.pep (partial)










1
..PHKTEQSVDL ETVSVVGKSR PRATSGLLHT STASDKIISG DTLRQKAVNL



 


51
  GDALDGVPGI HASQYGGGAS APVIRGQTGR RIKVLNHHGE TGDMADFSPD


 


101
  HAIMVDTALS QQVEILRGPV TLLYSSGNVA GLVDVADGKI PEKMPENGVS


 


151
  GELGLRLSSG NLEKLTSGGI NIGLGKNFVL HTEGLYRKSG DYAVPRYRNL


 


201
  KRLPDSHADS QTGSIGLSWV GEKGFIGVAY SDRRDQYGLP AHSHEYDDCH


 


251
  ADIIWQKSLI NKRYLQLYPH LLTEEDIDYD NPGLSCGFHD DDNAHAHTHS


 


301
  GRPWIDLRNK RYELRAEWKQ PFPGFEALRV HLNRNDYRHD EKAGDAVENF


 


351
  FNNQTQNARI ELRHQPIGRL KGSWGVQYLQ QKSSALSAIS EAVKQPMLLD


 


401
  NKVQHYSFFG VEQANWDNFT LEGGVRVEKQ KASIQYDKAL IDRENYYNHP


 


451
  LPDLGAHRQT ARSFALSGNW YFTPQHKLSL TASHQERLPS TQELYAHGKH


 


501
  VATNTFEVGN KHLNKERSNN IELALGYEGD RWQYNLALYR NRFGNYIYAQ


 


551
  TLNDGRGPKS IEDDSEMKLV RYNQSGADFY GAEGEIYFKP TPRYRIGVSG


 


601
  DYVRGRLKNL PSLPGREDAY GNRPFIAQDD QNAPRVPAAR LGFHLKASLT


 


651
  DRIDANLDYY RVFAQNKLAR YETRTPGHHM LNLGANYRRN TRYGEWNWYV


 


701
  KADNLLNQSV YAHSSFLSDT PQMGRSFTGG VNVKF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m147/g147 92.3% identity in 142 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 587>:










a147.seq




1
ATGCGACGAG AAGCCAAAAT GGCACAAACT ACACTCAAAC CCATTGTTTT


 


51
ATCAATTCTT TTAATCAACA CACCCCTCCT CTCCCAAGCG CATGGAACTG


 


101
AGCAATCAGT GGGCTTGGAA ACGGTCAGCG TCGTCGGCAA AAGCCGTCCG


 


151
CGCGCCACTT CGGGGCTGCT GCACACTTCT ACCGCCTCCG ACAAAATCAT


 


201
CAGCGGCGAC ACCTTGCGAC AAAAAGCCGT CAACTTGGGT GATGCTTTAG


 


251
ACGGCGTACC GGGCATTCAT GCCTCGCAAT ACGGCGGCGG CGCATCCGCT


 


301
CCCGTTATTC GCGGTCAAAC AGGCAGACGG ATTAAAGTGT TGAACCATCA


 


351
CGGCGAAACG GGCGACATGG CGGACTTCTC TCCAGACCAT GCAATCATGG


 


401
TGGACAGCGC CTTGTCGCAA CAGGTCGAAA TCCTGCGCGG TCCGGTTACG


 


451
CTCTTGTACA GCTCGGGCAA TGTGGCGGGG CTGGTCGATG TTGCCGATGG


 


501
CAAAATCCCC GAAAAAATGC CTGAAAACGG CGTATCGGGC GAACTCGGAT


 


551
TGCGTTTGAG CAGCGGCAAT CTGGAAAAAC TCACGTCCGG CGGCATCAAT


 


601
ATCGGTTTGG GCAAAAACTT TGTATTGCAC ACGGAAGGGC TGTACCGCAA


 


651
ATCGGGGGAT TACGCCGTAC CGCGTTACCG CAATCTGAAA CGCCTGCCCG


 


701
ACAGCCACGC CGATTCGCAA ACGGGCAGCA TCGGGCTGTC TTGGGTTGGC


 


751
GAAAAAGGCT TTATCGGCGC AGCATACAGC GACCGTCGCG ACCAATATGG


 


801
TCTGCCTGCC CACAGCCACG AATACGATGA TTGCCACGCC GACATCATCT


 


851
GGCAAAAGAG TTTGATTAAC AAACGCTATT TGCAGCTTTA TCCGCACCTG


 


901
TTGACCGAAG AAGACATCGA TTACGACAAT CCGGGCTTGA GCTGCGGCTT


 


951
TCACGACGAC GATGATGCAC ACGCCCATGC CCACAACGGC AAACCTTGGA


 


1001
TAGACCTGCG CAACAAACGC TACGAACTCC GCGCCGAATG GAAGCAACCG


 


1051
TTCCCCGGTT TTGAAGCCCT GCGCGTACAC CTGAACCGCA ACGACTACCG


 


1101
CCACGACGAA AAAGCAGGCG ATGCAGTAGA AAACTTTTTT AACAACCAAA


 


1151
CGCAAAACGC CCGTATCGAG TTGCGCCACC AACCCATAGG CCGTCTGAAA


 


1201
GGCAGCTGGG GCGTGCAATA TTTGGGACAA AAATCCAGTG CTTTATCTGC


 


1251
CACATCCGAA GCGGTCAAAC AACCGATGCT GCTTGACAAT AAAGTGCAAC


 


1301
ATTACAGCTT TTTCGGTGTA GAACAGGCAA ACTGGGACAA CTTCACGCTT


 


1351
GAAGGCGGCG TACGCGTGGA AAAACAAAAA GCCTCCATCC GCTACGACAA


 


1401
AGCATTGATT GATCGGGAAA ACTACTACAA CCATCCCCTG CCCGACCTCG


 


1451
GCGCGCACCG CCAAACCGCC CGCTCATTCG CACTTTCGGG CAACTGGTAT


 


1501
TTCACGCCAC AACACAAACT CAGCCTGACC GCCTCCCATC AGGAACGCCT


 


1551
GCCGTCAACG CAAGAGCTGT ACGCACACGG CAAACACGTC GCCACCAACA


 


1601
CCTTTGAAGT CGGCAACAAA CACCTCAACA AAGAGCGTTC CAACAATATC


 


1651
GAACTCGCGC TGGGCTACGA AGGCGACCGC TGGCAATACA ATCTGGCACT


 


1701
CTACCGCAAC CGCTTCGGCA ACTACATTTA CGCCCAAACC TTAAACGACG


 


1751
GACGCGGCCC CAAATCCATC GAAGACGACA GCGAAATGAA GCTCGTGCGC


 


1801
TACAACCAAT CCGGTGCGGA CTTCTACGGC GCGGAAGGCG AAATCTACTT


 


1851
CAAACCGACA CCGCGCTACC GCATCGGCGT TTCCGGCGAC TATGTACGAG


 


1901
GCCGTCTGAA AAACCTGCCT TCCCTACCCG GCAGGGAAGA CGCCTACGGC


 


1951
AACCGCCCAC TCATTGCCCA AGCCGACCAA AACGCCCCTC GCGTTCCGGC


 


2001
TGCGCGCCTC GGCGTCCACC TGAAAGCCTC GCTGACCGAC CGCATCGATG


 


2051
CCAATTTGGA CTACTACCGC GTGTTCGCCC AAAACAAACT CGCCCGCTAC


 


2101
GAAACGCGCA CGCCCGGACA CCATATGCTC AACCTCGGCG CAAACTACCG


 


2151
CCGCAATACG CGCTATGGCG AGTGGAATTG GTACGTCAAA GCCGACAACC


 


2201
TGCTCAACCA ATCCGTTTAC GCCCACAGCA GCTTCCTCTC TGATACGCCG


 


2251
CAAATGGGCC GCAGCTTTAC CGGCGGCGTG AACGTGAAGT TTTAA






This corresponds to the amino acid sequence <SEQ ID 588; ORF 147.a>:










a147.pep




1
MRREAKMAQT TLKPIVLSIL LINTPLLSQA HGTEQSVGLE TVSVVGKSRP


 


51
RATSGLLHTS TASDKIISGD TLRQKAVNLG DALDGVPGIH ASQYGGGASA


 


101
PVIRGQTGRR IKVLNHHGET GDMADFSPDH AIMVDSALSQ QVEILRGPVT


 


151
LLYSSGNVAG LVDVADGKIP EKMPENGVSG ELGLRLSSGN LEKLTSGGIN


 


201
IGLGKNFVLH TEGLYRKSGD YAVPRYRNLK RLPDSHADSQ TGSIGLSWVG


 


251
EKGFIGAAYS DRRDQYGLPA HSHEYDDCHA DIIWQKSLIN KRYLQLYPHL


 


301
LTEEDIDYDN PGLSCGFHDD DDAHAHAHNG KPWIDLRNKR YELRAEWKQP


 


351
FPGFEALRVH LNRNDYRHDE KAGDAVENFF NNQTQNARIE LRHQPIGRLK


 


401
GSWGVQYLGQ KSSALSATSE AVKQPMLLDN KVQHYSFFGV EQANWDNFTL


 


451
EGGVRVEKQK ASIRYDKALI DRENYYNHPL PDLGAHRQTA RSFALSGNWY


 


501
FTPQHKLSLT ASHQERLPST QELYAHGKHV ATNTFEVGNK HLNKERSNNI


 


551
ELALGYEGDR WQYNLALYRN RFGNYIYAQT LNDGRGPKSI EDDSEMKLVR


 


601
YNQSGADFYG AEGEIYFKPT PRYRIGVSGD YVRGRLKNLP SLPGREDAYG


 


651
NRPLIAQADQ NAPRVPAARL GVHLKASLTD RIDANLDYYR VFAQNKLARY


 


701
ETRTPGHHML NLGANYRRNT RYGEWNWYVK ADNLLNQSVY AHSSFLSDTP


 


751
QMGRSFTGGV NVKF*






m147/a147 98.1% identity in 734 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 589>:










g148.seq




1
ATGGCGTTAA AAACATCAAA CTTGGAACAC GCAATGctgg ttcaTCCCGA


 


51
AgctATgagt gtcggcgCGC TTGccgAcaa AATCCGCAAA AtcgaAAact


 


101
gGCCGCAAAA AGgcaTCTTA TTCCACGACA TCACGCCCGT CCTGCAAAGT


 


151
GCGGAATACT TCCGCCTTTT GGTCGATTTG CTGGTTTACC GCTATATGGA


 


201
TCAGAAAATC GACATCGTTG CCGGCTTGGA CGCGCGCGGC TTCATTATCG


 


251
GCGCGGCACT CGCCTACCAG CTCAaCGtcg gctTCGTCCC CATCCGCAAA


 


301
AAAGGCAAGC TGCCTTTTGA AACCGTATCG CAAAGCTAcg cgcTCGAATA


 


351
CGGGGAAGCT GCGGTGGAAA TCCACACCGa tgccgTCAAA CCCGGTTCGC


 


401
GCGTCCTGCT GGTCGATGAT TTGGTTGCCA CGGGCGGCAC AATGCTTGCC


 


451
GGGCTGGAAC TGATCCGCAA ACTCGGCGGG GAAATTGTCG AAgccgccgC


 


501
CATTTTGGAA TTTACCGACC TTCAAGGCGG CAAGAATATC CGCGCAAGTG


 


551
GCGCGCCCTT ATTTACCCTG CTTCAAAACG AAGGCTGCAT GAAAGGCTGA






This corresponds to the amino acid sequence <SEQ ID 590; ORF 148.ng>:










g148.pep




1
MALKTSNLEH AMLVHPEAMS VGALADKIRK IENWPQKGIL FHDITPVLQS


 


51
AEYFRLLVDL LVYRYMDQKI DIVAGLDARG FIIGAALAYQ LNVGFVPIRK


 


101
KGKLPFETVS QSYALEYGEA AVEIHTDAVK PGSRVLLVDD LVATGGTMLA


 


151
GLELIRKLGG EIVEAAAILE FTDLQGGKNI RASGAPLFTL LQNEGCMKG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 591>:










m148.seq




1
ATGGCGTTAA AAACATCAAA CTTGGAACAC GCAATGCTGG TTCATCCCGA


 


51
AGCTATGAGT GTCGGCGCGC TTGCCGACAA AATCCGCAAA ATCGAAAACT


 


101
GGCCGCAAAA AGGCATCTTA TTCCACGACA TCACGCCCGT CCTTCAAAGC


 


151
GCGGAATACT TCCGCCTTTT GGTTGATTTA TTGGTTTACC GCTATATGGA


 


201
TCAGAAAATC GACATCGTTG CCGGTTTGGA CGCGCGCGGC TTCATTATCG


 


251
GCGCGGCACT CGCCTACCAG CTCAACGTCG GTTTCGTCCC CATCCGCAAA


 


301
AAAGGCAAGC TGCCTTTTGA AACCGTATCG CAAAGCTACG CGCTCGAATA


 


351
CGGGGAAGCT GCGGTGGAAA TCCACACCGA TGCCGTCAAA CTCGGTTCGC


 


401
GCGTGCTGCT GGTCGATGAT TTGATTGCCA CGGGCGGCAC GATGCTTGCC


 


451
GGACTGGAAC TGATCCGCAA ACTCGGCGGA GAAATTGTCG AAGCCGCCGC


 


501
CATTTTGGAA TTTACCGACC TTCAAGGCGG CAAGAATATC CGTGCAAGCG


 


551
GCGCGCCCTT ATTTACCCTG CTTCAAAACG AAGGCTGTAT GAAGGGCTGA






This corresponds to the amino acid sequence <SEQ ID 592; ORF 148>:










m148.pep




1
MALKTSNLEH AMLVHPEAMS VGALADKIRK IENWPQKGIL FHDITPVLQS


 


51
AEYFRLLVDL LVYRYMDQKI DIVAGLDARG FIIGAALAYQ LNVGFVPIRK


 


101
KGKLPFETVS QSYALEYGEA AVEIHTDAVK LGSRVLLVDD LIATGGTMLA


 


151
GLELIRKLGG EIVEAAAILE FTDLQGGKNI RASGAPLFTL LQNEGCMKG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m148/g148 99.0% identity in 199 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 593>:










a148.seq




1
ATGGCGTTAA AAACATCAAA CTTGGAACAC GCAATGCTGG TTCATCCCGA


 


51
AGCTATGAGT GTCGGTGCGC TTGCCGACAA AATCCGCAAA ATCGAAAACT


 


101
GGCCGCAAAA AGGCATCTTA TTCCACGACA TCACGCCCGT CCTGCAAAGC


 


151
GCGGAATACT TCCGACTTTT GGTTGATTTA TTGGTTTACC GCTATATGGA


 


201
TCAGAAAATC GACATCGTTG CCGGTTTGGA CGCGCGCGGC TTCATTATCG


 


251
GCGCGGCACT CGCCTACCAG CTCAACGTCG GTTTCGTCCC CATCCGCAAA


 


301
AAAGGCAAGC TGCCTTTTGA AACCGTATCG CAAAGCTACG CGCTCGAATA


 


351
CGGGGAAGCT GCGGTGGAAA TCCACACCGA TGCCGTCAAA CTCGGTTCGC


 


401
GCGTGCTGCT GGTCGATGAT TTGGTTGCCA CGGGCGGCAC GATGCTTGCC


 


451
GGACTGGAGC TGATCCGCAA ACTCGGCGGG GAAATTGTCG AAGCCGCCGC


 


501
CATTTTGGAA TTTACCGACC TTCAAGGCGG CAAGAATATC CGTGCAAGCG


 


551
GCGCGCCCTT ATTTACCCTG CTTCAAAACG AAGGCTGTAT GAAGGGCTGA






This corresponds to the amino acid sequence <SEQ ID 594; ORF 148.a>:










a148.pep




1
MALKTSNLEH AMLVHPEAMS VGALADKIRK IENWPQKGIL FHDITPVLQS


 


51
AEYFRLLVDL LVYRYMDQKI DIVAGLDARG FIIGAALAYQ LNVGFVPIRK


 


101
KGKLPFETVS QSYALEYGEA AVEIHTDAVK LGSRVLLVDD LVATGGTMLA


 


151
GLELIRKLGG EIVEAAAILE FTDLQGGKNI RASGAPLFTL LQNEGCMKG*






m148/a148 99.5% identity in 199 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 595>:










g149.seq




1
ATGTTGATTG ACAACAATGT CCGCCATTAC AGCTTTTTCG GTGTAGAACA


 


51
GGCAAATTGG GACAACTTCA CGCTTGAAGG CGGCGTACGC GTGGAAAAAC


 


101
AAAAAGCCTC CATCCGGTAC GACAAAGCAT TGATTGATCG AGAAAACTAC


 


151
TACAACCAGC CCCTGCCCGA CCTCGGCGCG CACCGCCAAA CCGCCCGCTC


 


201
GTTCGCACTT TCGGGCAACT GGTATTTCAC GCCACACCAC AAACTCAGCC


 


251
TGACCGCCTC CCATCAGGAa cgCCTGCCGT CAACGCaagA actGtACgca


 


301
cacggcAAGC ACGtcgccac CAACACCTTT GAagtcggca acaaACACCT


 


351
CAACAAAGaG CgttccaacA atatcgaACT CGCGCTGGgc tAcaaaggcg


 


401
accGCTGGCA ATACAATCTG GCAGCCTACC GCAACCGAtT CGGCAACTAC


 


451
ATTTACGCCC AAACCTTAaa cgacggacgC GGCCCCAAAT CCATCgaaga


 


501
cgacagcgaA ATGaagcTCG TGCGCTACAA CCAATCCGGT GCCGACTTCT


 


551
ACGgcgcggA aggcgaaatc tACTTcaaaC CGAcACCGCG CTACCGCATC


 


601
GGTGTTTCCG GCGACTatgt acgaggccgT CTGAAAAACC TGCCGTCCCT


 


651
ACCCGGCAGG gaagatccCT AcggcAAACG TCccttcaTC GCACAAGCCG


 


701
ACCAAAACGC CCCCCGCATT ccggctGCGC GCCTCGGCTT CCACCTGAAA


 


751
ACCTCGCTAA CCGACCGTAT CGATGCCAAT TTGGACTACT ACCGCGTGTT


 


801
CGCCCAAAAC AAACTCGCCC GCTACGAAAC GCGTACGCCC GGACACCATA


 


851
TGCTCAACCT CGGTGCAAAC TACCGCCGCA ATACGCGCTA TGGCGAGTGG


 


901
AATTGGTACG TCAAAGCCGA CAACCTGCtc aACcaatCcg tTTACGCCCa


 


951
cAGCAGCTTC CTCTCTGATA CGCCGCAAAt gGGCCGCAGC TTtgccgGCg


 


1001
gcgtaAACGT GaAGTTttaA






This corresponds to the amino acid sequence <SEQ ID 596; ORF 149.ng>:










g149.pep




1
MLIDNNVRHY SFFGVEQANW DNFTLEGGVR VEKQKASIRY DKALIDRENY



 


51
YNQPLPDLGA HRQTARSFAL SGNWYFTPHH KLSLTASHQE RLPSTQELYA


 


101
HGKHVATNTF EVGNKHLNKE RSNNIELALG YKGDRWQYNL AAYRNRFGNY


 


151
IYAQTLNDGR GPKSIEDDSE MKLVRYNQSG ADFYGAEGEI YFKPTPRYRI


 


201
GVSGDYVRGR LKNLPSLPGR EDPYGKRPFI AQADQNAPRI PAARLGFHLK


 


251
TSLTDRIDAN LDYYRVFAQN KLARYETRTP GHHMLNLGAN YRRNTRYGEW


 


301
NWYVKADNLL NQSVYAHSSF LSDTPQMGRS FAGGVNVKF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 597>:










m149.seq




1
ATGCTGCTTG ACAACAAAGT GCAACATTAC AGCTTTTTCG GTGTAGAACA



 


51
GGCAAACTGG GACAACTTCA CGCTTGAAGG AGGCGTACGC GTGGAAAAAC


 


101
AAAAAGCCTC CATTCAGTAC GACAAAGCAT TGATTGATCG GGAAAACTAC


 


151
TACAACCACC CCCTGCCCGA CCTCGGCGCG CACCGCCAAA CCGCCCGCTC


 


201
ATTCGCACTT TCGGGCAACT GGTATTTCAC GCCACAACAC AAACTCAGCC


 


251
TGACCGCCTC CCATCAGGAA CGCCTGCCGT CAACGCAAGA GCTGTACGCA


 


301
CACGGCAAAC ACGTCGCCAC CAACACCTTT GAAGTCGGCA ACAAACACCT


 


351
CAACAAAGAG CGTTCCAACA ATATCGAACT CGCGCTGGGC TACGAAGGCG


 


401
ACCGCTGGCA ATACAATCTG GCACTCTACC GCAACCGCTT CGGTAACTAC


 


451
ATTTACGCCC AAACCTTAAA CGACGGACGC GGCCCCAAAT CCATCGAAGA


 


501
CGACAGCGAA ATGAAGCTCG TGCGCTACAA CCAATCCGGC GCCGACTTCT


 


551
ACGGCGCGGA AGGCGAAATC TACTTCAAAC CGACACCGCG CTACCGCATC


 


601
GGCGTTTCCG GCGACTATGT ACGAGGCCGT CTGAAAAACC TGCCTTCCCT


 


651
ACCCGGCAGA GAAGATGCCT ACGGCAACCG TCCTTTCATC GCACAGGACG


 


701
ACCAAAATGC CCCCCGTGTT CCGGCTGCGC GCCTCGGCTT CCACCTGAAA


 


751
GCCTCGCTGA CCGACCGTAT CGATGCCAAT TTGGACTACT ACCGCGTGTT


 


801
CGCCCAAAAC AAACTCGCCC GCTACGAAAC GCGCACGCCC GGACACCATA


 


851
TGCTCAACCT CGGCGCAAAC TACCGCCGCA ATACGCGCTA TGGCGAGTGG


 


901
AATTGGTACG TCAAAGCCGA CAACCTGCTC AACCAATCCG TTTACGCCCA


 


951
CAGCAGCTTT CTCTCTGATA CGCCGCAAAT GGGCCGCAGC TTTACCGGCG


 


1001
GCGTGAACGT GAAGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 598; ORF 149>:










m149.pep




1
MLLDNKVQHY SFFGVEQANW DNFTLEGGVR VEKQKASIQY DKALIDRENY



 


51
YNHPLPDLGA HRQTARSFAL SGNWYFTPQH KLSLTASHQE RLPSTQELYA


 


101
HGKHVATNTF EVGNKHLNKE RSNNIELALG YEGDRWQYNL ALYRNRFGNY


 


151
IYAQTLNDGR GPKSIEDDSE MKLVRYNQSG ADFYGAEGEI YFKPTPRYRI


 


201
GVSGDYVRGR LKNLPSLPGR EDAYGNRPFI AQDDQNAPRV PAARLGFHLK


 


251
ASLTDRIDAN LDYYRVFAQN KLARYETRTP GHHMLNLGAN YRRNTRYGEW


 


301
NWYVKADNLL NQSVYAHSSF LSDTPQMGRS FTGGVNVKF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 149 shows 95.9% identity over a 339 aa overlap with a predicted ORF (ORF 149.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 599>:










a149.seq




1
ATGCTGCTTG ACAATAAAGT GCAACATTAC AGCTTTTTCG GTGTAGAACA



 


51
GGCAAACTGG GACAACTTCA CGCTTGAAGG CGGCGTACGC GTGGAAAAAC


 


101
AAAAAGCCTC CATCCGCTAC GACAAAGCAT TGATTGATCG GGAAAACTAC


 


151
TACAACCATC CCCTGCCCGA CCTCGGCGCG CACCGCCAAA CCGCCCGCTC


 


201
ATTCGCACTT TCGGGCAACT GGTATTTCAC GCCACAACAC AAACTCAGCC


 


251
TGACCGCCTC CCATCAGGAA CGCCTGCCGT CAACGCAAGA GCTGTACGCA


 


301
CACGGCAAAC ACGTCGCCAC CAACACCTTT GAAGTCGGCA ACAAACACCT


 


351
CAACAAAGAG CGTTCCAACA ATATCGAACT CGCGCTGGGC TACGAAGGCG


 


401
ACCGCTGGCA ATACAATCTG GCACTCTACC GCAACCGCTT CGGCAACTAC


 


451
ATTTACGCCC AAACCTTAAA CGACGGACGC GGCCCCAAAT CCATCGAAGA


 


501
CGACAGCGAA ATGAAGCTCG TGCGCTACAA CCAATCCGGT GCGGACTTCT


 


551
ACGGCGCGGA AGGCGAAATC TACTTCAAAC CGACACCGCG CTACCGCATC


 


601
GGCGTTTCCG GCGACTATGT ACGAGGCCGT CTGAAAAACC TGCCTTCCCT


 


651
ACCCGGCAGG GAAGACGCCT ACGGCAACCG CCCACTCATT GCCCAAGCCG


 


701
ACCAAAACGC CCCTCGCGTT CCGGCTGCGC GCCTCGGCGT CCACCTGAAA


 


751
GCCTCGCTGA CCGACCGCAT CGATGCCAAT TTGGACTACT ACCGCGTGTT


 


801
CGCCCAAAAC AAACTCGCCC GCTACGAAAC GCGCACGCCC GGACACCATA


 


851
TGCTCAACCT CGGCGCAAAC TACCGCCGCA ATACGCGCTA TGGCGAGTGG


 


901
AATTGGTACG TCAAAGCCGA CAACCTGCTC AACCAATCCG TTTACGCCCA


 


951
CAGCAGCTTC CTCTCTGATA CGCCGCAAAT GGGCCGCAGC TTTACCGGCG


 


1001
GCGTGAACGT GAAGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 600; ORF 149.a>:










a149.pep




1
MLLDNKVQHY SFFGVEQANW DNFTLEGGVR VEKQKASIRY DKALIDRENY



 


51
YNHPLPDLGA HRQTARSFAL SGNWYFTPQH KLSLTASHQE RLPSTQELYA


 


101
HGKHVATNTF EVGNKHLNKE RSNNIELALG YEGDRWQYNL ALYRNRFGNY


 


151
IYAQTLNDGR GPKSIEDDSE MKLVRYNQSG ADFYGAEGEI YFKPTPRYRI


 


201
GVSGDYVRGR LKNLPSLPGR EDAYGNRPLI AQADQNAPRV PAARLGVHLK


 


251
ASLTDRIDAN LDYYRVFAQN KLARYETRTP GHHMLNLGAN YRRNTRYGEW


 


301
NWYVKADNLL NQSVYAHSSF LSDTPQMGRS FTGGVNVKF*






m149/a149 98.8% identity in 339 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 601>:










g149-1.seq




1
ATGGCACAAA TCACACTCAA ACCCATTGTT TTATCAATTC TTTTAATCAA



 


51
CACACCCCTC CTCGCCCAAG CGCATGAAAC TGAGCAATCG GTGGGCTTGG


 


101
AAACGGTCAG CGTCGTCGGC AAAAGCCGTC CGCGCGCGAC TTCGGGGCTG


 


151
CTGCACACTT CGACCGCCTC CGACAAAATC ATCTCCGGCG ATACTTTGCG


 


201
CCAAAAAGCC GTCAACTTGG GCGACGCTTT GGACGGCGTA CCGGGCATCC


 


251
ACGCTTCGCA ATACGGCGGC GGCGCATCCG CTCCCGTTAT TCGCGGTCAA


 


301
ACGGGCAGAC GGATTAAAGT ATTGAACCAT CACGGCGAAA CGGGCGATAT


 


351
GGCGGACTTT TCTCCCGATC ACGCCATTAT GGTAGATACC GCCTTGTCGC


 


401
AACAGGTTGA AATCCTGCGC GGGCCGGTTA CGCTCTTGTA CAGCTCGGGC


 


451
AATGTGGCGG GGCTGGTCGA TGTTGCCGAT GGAAAAATCC CCGAAAAAAT


 


501
GCCTGAAAAC GGCGTATCGG GCGaagccgG ATTGCGTTTG AGCAGCGGCA


 


551
ATTTAGAAAA ACTGACATCC GCAGGCATCA ATATCGGACT GGGCAAAAAC


 


601
TTCGTGCTGC ATACCGAAGG CTTGTACCGC AAATCGGGCG ATTACGCCGT


 


651
ACCGCGTTAC CGCAATCTGA AACGCCTGCC CGACAGCCAT GCCGATTCGC


 


701
AAACGGGCAG CATCGGGCTG TCTTGGGTGG GCGAAAAAGG CTTTATCGGC


 


751
GCAGCATACA GCGACCGTCG CGACCGCTAC GGCCTGCCTG CCCACAGCCA


 


801
CGAATACGAT GATTGCCACG CCGACATCAT CTGGCAAAAG AGTTTGATCA


 


851
ACAAACGCTA TTTGCAGCTT TATCCGCACT TGTTGACCGA AGAAGACATC


 


901
GATTACGACA ATCCGGGCTT GAGCTGCGGC TTCCACGACG GCGACGGTGC


 


951
ACACGCACAC ACCCACAACG GCAAACCGTG GATAGACCTG CGCAACAAAC


 


1001
GCTACGAACT CCGCGCCGAA TGGAAGCAGC CATTCCCCGG TTTTGAAGCC


 


1051
CTGCGCGTAC ATCTGAACCG CAATGACTAC CACCACGACG AAAAAGCAGG


 


1101
CGATGCAGTA GAAAACTTCT TCAACAACAA AACACACAAC GCCCGTATCG


 


1151
AGTTGCGCCA CCAACCCATA GGCCGTCTGA AAGGCAGCTG GGGCGTGCAA


 


1201
TATTTGGGAC AAAAATCCAG CGCGCTTTCC GCCATTCCCG AAACCGTCCA


 


1251
ACAACCGATG TTGATTGACA ACAATGTCCG CCATTACAGC TTTTTCGGTG


 


1301
TAGAACAGGC AAATTGGGAC AACTTCACGC TTGAAGGCGG CGTACGCGTG


 


1351
GAAAAACAAA AAGCCTCCAT CCGGTACGAC AAAGCATTGA TTGATCGAGA


 


1401
AAACTACTAC AACCAGCCCC TGCCCGACCT CGGCGCGCAC CGCCAAACCG


 


1451
CCCGCTCGTT CGCACTTTCG GGCAACTGGT ATTTCACGCC ACACCACAAA


 


1501
CTCAGCCTGA CCGCCTCCCA TCAGGAACGC CTGCCGTCAA CGCAAGAACT


 


1551
GTACGCACAC GGCAAGCACG TCGCCACCAA CACCTTTGAA GTCGGCAACA


 


1601
AACACCTCAA CAAAGAGCGT TCCAACAATA TCGAACTCGC GCTGGGCTAC


 


1651
GAAGGCGACC GCTGGCAATA CAATCTGGCA GCCTACCGCA ACCGATTCGG


 


1701
CAACTACATT TACGCCCAAA CCTTAAACGA CGGACGCGGC CCCAAATCCA


 


1751
TCGAAGACGA CAGCGAAATG AAGCTCGTGC GCTACAACCA ATCCGGTGCC


 


1801
GACTTCTACG GCGCGGAAGG CGAAATCTAC TTCAAACCGA CACCGCGCTA


 


1851
CCGCATCGGT GTTTCCGGCG ACTATGTACG AGGCCGTCTG AAAAACCTGC


 


1901
CGTCCCTACC CGGCAGGGAA GATCCCTACG GCAAACGTCC CTTCATCGCA


 


1951
CAAGCCGACC AAAACGCCCC CCGCATTCCG GCTGCGCGCC TCGGCTTCCA


 


2001
CCTGAAAACC TCGCTAACCG ACCGTATCGA TGCCAATTTG GACTACTACC


 


2051
GCGTGTTCGC CCAAAACAAA CTCGCCCGCT ACGAAACGCG TACGCCCGGA


 


2101
CACCATATGC TCAACCTCGG TGCAAACTAC CGCCGCAATA CGCGCTATGG


 


2151
CGAGTGGAAT TGGTACGTCA AAGCCGACAA CCTGCTCAAC CAATCCGTTT


 


2201
ACGCCCACAG CAGCTTCCTC TCTGATACGC CGCAAATGGG CCGCAGCTTT


 


2251
ACCGGCGGCG TAAACGTGAA GTTTTAA






This corresponds to the amino acid sequence <SEQ ID 602; ORF 149-1.ng>:









g149-1.pep




1
MAQITLKPIV LSILLINTPL LAQAHETEQS VGLETVSVVG KSRPRATSGL



 


51
LHTSTASDKI ISGDTLRQKA VNLGDALDGV PGIHASQYGG GASAPVIRGQ


 


101
TGRRIKVLNH HGETGDMADF SPDHAIMVDT ALSQQVEILR GPVTLLYSSG


 


151
NVAGLVDVAD GKIPEKMPEN GVSGEAGLRL SSGNLEKLTS AGINIGLGKN


 


201
FVLHTEGLYR KSGDYAVPRY RNLKRLPDSH ADSQTGSIGL SWVGEKGFIG


 


251
AAYSDRRDRY GLPAHSHEYD DCHADIIWQK SLINKRYLQL YPHLLTEEDI


 


301
DYDNPGLSCG FHDGDGAHAH THNGKPWIDL RNKRYELRAE WKQPFPGFEA


 


351
LRVHLNRNDY HHDEKAGDAV ENFFNNKTHN ARIELRHQPI GRLKGSWGVQ


 


401
YLGQKSSALS AIPETVQQPM LIDNNVRHYS FFGVEQANWD NFTLEGGVRV


 


451
EKQKASIRYD KALIDRENYY NQPLPDLGAH RQTARSFALS GNWYFTPHHK


 


501
LSLTASHQER LPSTQELYAH GKHVATNTFE VGNKHLNKER SNNIELALGY


 


551
EGDRWQYNLA AYRNRFGNYI YAQTLNDGRG PKSIEDDSEM KLVRYNQSGA


 


601
DFYGAEGEIY FKPTPRYRIG VSGDYVRGRL KNLPSLPGRE DPYGKRPFIA


 


651
QADQNAPRIP AARLGFHLKT SLTDRIDANL DYYRVFAQNK LARYETRTPG


 


701
HHMLNLGANY RRNTRYGEWN WYVKADNLLN QSVYAHSSFL SDTPQMGRSF


 


751
TGGVNVKF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 603>:










m149-1.seq




1
ATGGCACAAA CTACACTCAA ACCCATTGTT TTATCAATTC TTTTAATCAA



 


51
CACACCCCTC CTCGCCCAAG CGCATGAAAC TGAGCAATCG GTGGATTTGG


 


101
AAACGGTCAG CGTCGTCGGC AAAAGCCGTC CGCGCGCCAC GTCGGGGCTG


 


151
TTGCACACTT CGACCGCCTC CGACAAAATC ATCTCCGGCG ATACCTTGCG


 


201
CCAAAAAGCC GTCAACTTGG GCGACGCTTT AGACGGCGTA CCGGGCATCC


 


251
ACGCTTCGCA ATACGGCGGC GGCGCGTCTG CTCCCGTCAT TCGCGGTCAA


 


301
ACAGGCAGGC GGATTAAAGT GTTGAACCAT CACGGCGAAA CAGGCGATAT


 


351
GGCGGATTTT TCGCCCGATC ACGCCATTAT GGTAGATACC GCCTTGTCGC


 


401
AACAGGTCGA AATCCTGCGC GGGCCGGTTA CGCTCTTGTA CAGCTCGGGC


 


451
AATGTGGCGG GGCTGGTCGA TGTTGCCGAT GGCAAAATCC CCGAAAAAAT


 


501
GCCTGAAAAC GGCGTATCGG GCGAACTCGG ATTGCGTTTG AGCAGCGGCA


 


551
ATCTGGAAAA ACTCACGTCC GGCGGCATCA ATATCGGTTT GGGCAAAAAC


 


601
TTTGTATTGC ACACGGAAGG GCTGTACCGC AAATCGGGGG ATTACGCCGT


 


651
ACCGCGTTAC CGCAATCTGA AACGCCTGCC CGACAGCCAC GCCGATTCGC


 


701
AAACGGGCAG CATCGGGCTG TCTTGGGTTG GCGAAAAAGG TTTTATCGGC


 


751
GTAGCGTACA GCGACCGTCG CGACCAATAT GGTCTGCCTG CCCACAGCCA


 


801
CGAATACGAT GATTGCCACG CCGACATCAT CTGGCAAAAG AGCTTGATTA


 


851
ACAAACGCTA TTTACAGCTT TATCCGCACC TGTTGACCGA AGAAGACATC


 


901
GATTACGACA ATCCGGGCTT GAGCTGCGGC TTCCACGACG ACGATAATGC


 


951
ACACGCACAC ACCCACAGCG GCAGACCGTG GATAGACCTG CGCAACAAAC


 


1001
GCTACGAACT CCGTGCCGAA TGGAAGCAAC CGTTCCCCGG TTTTGAAGCC


 


1051
CTGCGCGTAC ACCTGAACCG CAACGACTAC CGCCACGACG AAAAAGCAGG


 


1101
CGATGCAGTC GAAAACTTTT TTAACAACCA AACGCAAAAC GCCCGCATCG


 


1151
AGTTGCGCCA CCAACCCATA GGTCGTCTGA AAGGCAGCTG GGGCGTGCAA


 


1201
TATTTACAAC AAAAATCCAG TGCTTTATCT GCCATATCCG AAGCGGTTAA


 


1251
ACAACCGATG CTGCTTGACA ACAAAGTGCA ACATTACAGC TTTTTCGGTG


 


1301
TAGAACAGGC AAACTGGGAC AACTTCACGC TTGAAGGAGG CGTACGCGTG


 


1351
GAAAAACAAA AAGCCTCCAT TCAGTACGAC AAAGCATTGA TTGATCGGGA


 


1401
AAACTACTAC AACCACCCCC TGCCCGACCT CGGCGCGCAC CGCCAAACCG


 


1451
CCCGCTCATT CGCACTTTCG GGCAACTGGT ATTTCACGCC ACAACACAAA


 


1501
CTCAGCCTGA CCGCCTCCCA TCAGGAACGC CTGCCGTCAA CGCAAGAGCT


 


1551
GTACGCACAC GGCAAACACG TCGCCACCAA CACCTTTGAA GTCGGCAACA


 


1601
AACACCTCAA CAAAGAGCGT TCCAACAATA TCGAACTCGC GCTGGGCTAC


 


1651
GAAGGCGACC GCTGGCAATA CAATCTGGCA CTCTACCGCA ACCGCTTCGG


 


1701
TAACTACATT TACGCCCAAA CCTTAAACGA CGGACGCGGC CCCAAATCCA


 


1751
TCGAAGACGA CAGCGAAATG AAGCTCGTGC GCTACAACCA ATCCGGCGCC


 


1801
GACTTCTACG GCGCGGAAGG CGAAATCTAC TTCAAACCGA CACCGCGCTA


 


1851
CCGCATCGGC GTTTCCGGCG ACTATGTACG AGGCCGTCTG AAAAACCTGC


 


1901
CTTCCCTACC CGGCAGAGAA GATGCCTACG GCAACCGTCC TTTCATCGCA


 


1951
CAGGACGACC AAAATGCCCC CCGTGTTCCG GCTGCGCGCC TCGGCTTCCA


 


2001
CCTGAAAGCC TCGCTGACCG ACCGTATCGA TGCCAATTTG GACTACTACC


 


2051
GCGTGTTCGC CCAAAACAAA CTCGCCCGCT ACGAAACGCG CACGCCCGGA


 


2101
CACCATATGC TCAACCTCGG CGCAAACTAC CGCCGCAATA CGCGCTATGG


 


2151
CGAGTGGAAT TGGTACGTCA AAGCCGACAA CCTGCTCAAC CAATCCGTTT


 


2201
ACGCCCACAG CAGCTTTCTC TCTGATACGC CGCAAATGGG CCGCAGCTTT


 


2251
ACCGGCGGCG TGAACGTGAA GTTTTAA






This corresponds to the amino acid sequence <SEQ ID 604; ORF 149-1>:










m149-1.pep




1
MAQTTLKPIV LSILLINTPL LAQAHETEQS VDLETVSVVG KSRPRATSGL



 


51
LHTSTASDKI ISGDTLRQKA VNLGDALDGV PGIHASQYGG GASAPVIRGQ


 


101
TGRRIKVLNH HGETGDMADF SPDHAIMVDT ALSQQVEILR GPVTLLYSSG


 


151
NVAGLVDVAD GKIPEKMPEN GVSGELGLRL SSGNLEKLTS GGINIGLGKN


 


201
FVLHTEGLYR KSGDYAVPRY RNLKRLPDSH ADSQTGSIGL SWVGEKGFIG


 


251
VAYSDRRDQY GLPAHSHEYD DCHADIIWQK SLINKRYLQL YPHLLTEEDI


 


301
DYDNPGLSCG FHDDDNAHAH THSGRPWIDL RNKRYELRAE WKQPFPGFEA


 


351
LRVHLNRNDY RHDEKAGDAV ENFFNNQTQN ARIELRHQPI GRLKGSWGVQ


 


401
YLQQKSSALS AISEAVKQPM LLDNKVQHYS FFGVEQANWD NFTLEGGVRV


 


451
EKQKASIQYD KALIDRENYY NHPLPDLGAH RQTARSFALS GNWYFTPQHK


 


501
LSLTASHQER LPSTQELYAH GKHVATNTFE VGNKHLNKER SNNIELALGY


 


551
EGDRWQYNLA LYRNRFGNYI YAQTLNDGRG PKSIEDDSEM KLVRYNQSGA


 


601
DFYGAEGEIY FKPTPRYRIG VSGDYVRGRL KNLPSLPGRE DAYGNRPFIA


 


651
QDDQNAPRVP AARLGFHLKA SLTDRIDANL DYYRVFAQNK LARYETRTPG


 


701
HHMLNLGANY RRNTRYGEWN WYVKADNLLN QSVYAHSSFL SDTPQMGRSF


 


751
TGGVNVKF*






m149-1/g149-1 96.2% identity in 758 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 605>:










a149-1.seq




1
ATGGCACAAA CTACACTCAA ACCCATTGTT TTATCAATTC TTTTAATCAA



 


51
CACACCCCTC CTCTCCCAAG CGCATGGAAC TGAGCAATCA GTGGGCTTGG


 


101
AAACGGTCAG CGTCGTCGGC AAAAGCCGTC CGCGCGCCAC TTCGGGGCTG


 


151
CTGCACACTT CTACCGCCTC CGACAAAATC ATCAGCGGCG ACACCTTGCG


 


201
ACAAAAAGCC GTCAACTTGG GTGATGCTTT AGACGGCGTA CCGGGCATTC


 


251
ATGCCTCGCA ATACGGCGGC GGCGCATCCG CTCCCGTTAT TCGCGGTCAA


 


301
ACAGGCAGAC GGATTAAAGT GTTGAACCAT CACGGCGAAA CGGGCGACAT


 


351
GGCGGACTTC TCTCCAGACC ATGCAATCAT GGTGGACAGC GCCTTGTCGC


 


401
AACAGGTCGA AATCCTGCGC GGTCCGGTTA CGCTCTTGTA CAGCTCGGGC


 


451
AATGTGGCGG GGCTGGTCGA TGTTGCCGAT GGCAAAATCC CCGAAAAAAT


 


501
GCCTGAAAAC GGCGTATCGG GCGAACTCGG ATTGCGTTTG AGCAGCGGCA


 


551
ATCTGGAAAA ACTCACGTCC GGCGGCATCA ATATCGGTTT GGGCAAAAAC


 


601
TTTGTATTGC ACACGGAAGG GCTGTACCGC AAATCGGGGG ATTACGCCGT


 


651
ACCGCGTTAC CGCAATCTGA AACGCCTGCC CGACAGCCAC GCCGATTCGC


 


701
AAACGGGCAG CATCGGGCTG TCTTGGGTTG GCGAAAAAGG CTTTATCGGC


 


751
GCAGCATACA GCGACCGTCG CGACCAATAT GGTCTGCCTG CCCACAGCCA


 


801
CGAATACGAT GATTGCCACG CCGACATCAT CTGGCAAAAG AGTTTGATTA


 


851
ACAAACGCTA TTTGCAGCTT TATCCGCACC TGTTGACCGA AGAAGACATC


 


901
GATTACGACA ATCCGGGCTT GAGCTGCGGC TTTCACGACG ACGATGATGC


 


951
ACACGCCCAT GCCCACAACG GCAAACCTTG GATAGACCTG CGCAACAAAC


 


1001
GCTACGAACT CCGCGCCGAA TGGAAGCAAC CGTTCCCCGG TTTTGAAGCC


 


1051
CTGCGCGTAC ACCTGAACCG CAACGACTAC CGCCACGACG AAAAAGCAGG


 


1101
CGATGCAGTA GAAAACTTTT TTAACAACCA AACGCAAAAC GCCCGTATCG


 


1151
AGTTGCGCCA CCAACCCATA GGCCGTCTGA AAGGCAGCTG GGGCGTGCAA


 


1201
TATTTGGGAC AAAAATCCAG TGCTTTATCT GCCACATCCG AAGCGGTCAA


 


1251
ACAACCGATG CTGCTTGACA ATAAAGTGCA ACATTACAGC TTTTTCGGTG


 


1301
TAGAACAGGC AAACTGGGAC AACTTCACGC TTGAAGGCGG CGTACGCGTG


 


1351
GAAAAACAAA AAGCCTCCAT CCGCTACGAC AAAGCATTGA TTGATCGGGA


 


1401
AAACTACTAC AACCATCCCC TGCCCGACCT CGGCGCGCAC CGCCAAACCG


 


1451
CCCGCTCATT CGCACTTTCG GGCAACTGGT ATTTCACGCC ACAACACAAA


 


1501
CTCAGCCTGA CCGCCTCCCA TCAGGAACGC CTGCCGTCAA CGCAAGAGCT


 


1551
GTACGCACAC GGCAAACACG TCGCCACCAA CACCTTTGAA GTCGGCAACA


 


1601
AACACCTCAA CAAAGAGCGT TCCAACAATA TCGAACTCGC GCTGGGCTAC


 


1651
GAAGGCGACC GCTGGCAATA CAATCTGGCA CTCTACCGCA ACCGCTTCGG


 


1701
CAACTACATT TACGCCCAAA CCTTAAACGA CGGACGCGGC CCCAAATCCA


 


1751
TCGAAGACGA CAGCGAAATG AAGCTCGTGC GCTACAACCA ATCCGGTGCG


 


1801
GACTTCTACG GCGCGGAAGG CGAAATCTAC TTCAAACCGA CACCGCGCTA


 


1851
CCGCATCGGC GTTTCCGGCG ACTATGTACG AGGCCGTCTG AAAAACCTGC


 


1901
CTTCCCTACC CGGCAGGGAA GACGCCTACG GCAACCGCCC ACTCATTGCC


 


1951
CAAGCCGACC AAAACGCCCC TCGCGTTCCG GCTGCGCGCC TCGGCGTCCA


 


2001
CCTGAAAGCC TCGCTGACCG ACCGCATCGA TGCCAATTTG GACTACTACC


 


2051
GCGTGTTCGC CCAAAACAAA CTCGCCCGCT ACGAAACGCG CACGCCCGGA


 


2101
CACCATATGC TCAACCTCGG CGCAAACTAC CGCCGCAATA CGCGCTATGG


 


2151
CGAGTGGAAT TGGTACGTCA AAGCCGACAA CCTGCTCAAC CAATCCGTTT


 


2201
ACGCCCACAG CAGCTTCCTC TCTGATACGC CGCAAATGGG CCGCAGCTTT


 


2251
ACCGGCGGCG TGAACGTGAA GTTTTAA






This corresponds to the amino acid sequence <SEQ ID 606; ORF 149-1.a>:










a149-1.pep




1
MAQTTLKPIV LSILLINTPL LSQAHGTEQS VGLETVSVVG KSRPRATSGL



 


51
LHTSTASDKI ISGDTLRQKA VNLGDALDGV PGIHASQYGG GASAPVIRGQ


 


101
TGRRIKVLNH HGETGDMADF SPDHAIMVDS ALSQQVEILR GPVTLLYSSG


 


151
NVAGLVDVAD GKIPEKMPEN GVSGELGLRL SSGNLEKLTS GGINIGLGKN


 


201
FVLHTEGLYR KSGDYAVPRY RNLKRLPDSH ADSQTGSIGL SWVGEKGFIG


 


251
AAYSDRRDQY GLPAHSHEYD DCHADIIWQK SLINKRYLQL YPHLLTEEDI


 


301
DYDNPGLSCG FHDDDDAHAH AHNGKPWIDL RNKRYELRAE WKQPFPGFEA


 


351
LRVHLNRNDY RHDEKAGDAV ENFFNNQTQN ARIELRHQPI GRLKGSWGVQ


 


401
YLGQKSSALS ATSEAVKQPM LLDNKVQHYS FFGVEQANWD NFTLEGGVRV


 


451
EKQKASIRYD KALIDRENYY NHPLPDLGAH RQTARSFALS GNWYFTPQHK


 


501
LSLTASHQER LPSTQELYAH GKHVATNTFE VGNKHLNKER SNNIELALGY


 


551
EGDRWQYNLA LYRNRFGNYI YAQTLNDGRG PKSIEDDSEM KLVRYNQSGA


 


601
DFYGAEGEIY FKPTPRYRIG VSGDYVRGRL KNLPSLPGRE DAYGNRPLIA


 


651
QADQNAPRVP AARLGVHLKA SLTDRIDANL DYYRVFAQNK LARYETRTPG


 


701
HHMLNLGANY RRNTRYGEWN WYVKADNLLN QSVYAHSSFL SDTPQMGRSF


 


751
TGGVNVKF*






a149-1/m149-1 98.0% identity in 758 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 607>:









g150.seq (partial)










1
..TACTGCAAGG CAGACCCCTT TCCCGCCGCC CTGCTGGCCA ATCAGAAAAT



 


51
  CACCGCCCGC CAATCCGATA AAGACGTGCG CCACATCGAA ATCGATTTGA


 


101
  GCGGTTCGGA TTTGCACTAC CTCCCGGGCG ACGCGCTCGG CGTTTGGTTT


 


151
  GACAACGATC CGGCACTGGT CGGGGAAATC CTAGACCTGC TCGGCATCAA


 


201
  TCCGGCAACG GAAATACAGG CGGGCGGAAA AACCCTGCCG GTTGCCTCCG


 


251
  CACTGTTATC CCATTTCGAA CTCACGCAAA ACACCCCCGC CTTTGTCAAA


 


301
  GGCTATGCCA CGTTCGCCGA TAATGACGAA CTCGACCGTA TTGCTGCCGA


 


351
  CAACGCCGTT TTGCAAGGCT TTGTGCAAAG CACGCCGATT GCCGGTGTGC


 


401
  TGCACCGCTT CCCGGCAAAA CTGACGGCGG AACAATTCGC CGGCCTGCTG


 


451
  CGCCCGCTTG CGCCGCGCCT GTATTCGATT TCCTCGTCGC AGGCGGAAGC


 


501
  GGGGGACGAA GTGCACCTGA CCGTCGGCGC AGTGCGTTTC GAACACGAAG


 


551
  GGCGCGCCAG GGCGGGCGGC GCATCGGGTT TCTTTGCCGA CCGGCTGGAA


 


601
  GAGGACGGCA CGGTGCGCGT GTTTGCGGAA CGCAACGACG GCTTCAGGCT


 


651
  GCCCGAAGAC AGCCGCAAGC CGATTGTGAT GATCGGCTCC GGTACCGGCG


 


701
  TCGCACCGTT CCGCGCCTTC GTCCAACAAC GTGCCGCAGA AAATGCGGAA


 


751
  GGCAGAAACT GGCTGATTTT CGGCAATCCG CATTTTGCCG CCGACTTCCT


 


801
  CTATCAGACC GAATGGCAGC AGTTTGCCAA AGACGGCTTC CTGCACAGAT


 


851
  ATGACTTCGC CTGGTCGCGC GATCAGGAAG AAAAAATCTA TGTGCAGGAC


 


901
  AAAATCCGCG AACAGGCGGA AGGACTTTGG CAATGGCTGC AGGAAGGCGC


 


951
  GCATATCTAT GTGTGCGGCG ATGCGGCAAA AATGGCAAAA GAAGTGGAAG


 


1001
  CCGCCTTGCT GGATGTGATT ATCGGGGCAG GGCATTCGGA CGAAGACGGC


 


1051
  GCAGAAGGAT ATTTGGATAT GCTGCGCGAA GAAAAACGCT ATCAGCGTGA


 


1101
  TGTTTATTGA






This corresponds to the amino acid sequence <SEQ ID 608; ORF 150.ng>:









g150.pep (partial)










1
..YCKADPFPAA LLANQKITAR QSDKDVRHIE IDLSGSDLHY LPGDALGVWF



 


51
  DNDPALVGEI LDLLGINPAT EIQAGGKTLP VASALLSHFE LTQNTPAFVK


 


101
  GYATFADNDE LDRIAADNAV LQGFVQSTPI AGVLHRFPAK LTAEQFAGLL


 


151
  RPLAPRLYSI SSSQAEAGDE VHLTVGAVRF EHEGRARAGG ASGFFADRLE


 


201
  EDGTVRVFAE RNDGFRLPED SRKPIVMIGS GTGVAPFRAF VQQRAAENAE


 


251
  GRNWLIFGNP HFAADFLYQT EWQQFAKDGF LHRYDFAWSR DQEEKIYVQD


 


301
  KIREQAEGLW QWLQEGAHIY VCGDAAKMAK EVEAALLDVI IGAGHSDEDG


 


351
  AEGYLDMLRE EKRYQRDVY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 609>:










m150.seq




1
ATGCAGAACA CAAATCCGCC ATTACCGCCT CTGCCGCCCG AAATCACGCA



 


51
GCTCCTGTCG GGGCTGGACG CGGCACAATG GGCGTGGCTG TCCGGCTACG


 


101
CTTGGGCAAA AGCAGGAAAC GGGGCATCTG CAGGACTGCC CGCGCTTCAG


 


151
ACGGCATTGC CGGCGGCAGA ACCTTTTTCC GTAACCGTCC TTTCCGCCTC


 


201
GCAAACCGGC AATGCGAAAT CCGTTGCCGA CAAAGCGGCG GACAGCCTGG


 


251
AAGCCGCCGG CATCCAAGTC AGTCGCGCCG AACTGAAAGA CTATAAGGCG


 


301
AAAAACATCG CCGGCGAACG CCGCCTGCTG CTGGTTACCT CCACCCAAGG


 


351
CGAAGGCGAA CCGCCGAAAG AAGCCGTCGT GCTGCACAAA CTGCTGAACG


 


401
GCAAAAAAGC CCCGAAATTG GACAAACTCC AATTTGCCGT ACTGGGTTTG


 


451
GGCGACAGTT CCTATCCGAA TTTCTGTCAG GCAGGTAAAG ATTTCGACCG


 


501
GCGTTTTGAA GAATTGGGCG CAAAACGGCT GCTCGAACGC GTTGATGCGG


 


551
ATTTGGACTT TACCGCCTCC GCAAACGCCT GGACAGATAA TATCGCCGCA


 


601
CTCTTAAAAG AAGAAGCCGC AAAAAACCGG GCAACGCCCG CGCCGCAGAC


 


651
AACGCCCCCC GCCGGCCTTC AGACGGCACC GGATGGCAGG TACTGCAAGG


 


701
CAGCCCCCTT TCCCGCCGCC CTGCTGGCCA ATCAGAAAAT CACCGCCCGC


 


751
CAATCCGATA AAGACGTGCG CCACATCGAA ATCGATTTGA GCGGTTCGGA


 


801
TTTGCACTAC CTCCCGGGCG ACGCGCTCGG CGTTTGGTTT GACAACGATC


 


851
CGGCACTGGT CAGGGAAATC CTAGACCTGC TCGGCATCGA TCCGGCAACG


 


901
GAAATACAGG CGGGCGGAAA GATGATGCCG GTTGCGCGCG CACTTTCATC


 


951
TCATTTCGAA CTCACGCAAA ACACTCCGGC TTTCGTCAAA GGCTATGCCG


 


1001
CGTTCGCCCA TTATGAAGAA CTCGATAAAA TCATTGCCGA TAACGCCGTT


 


1051
TTGCAGGATT TCGTGCAAAA CACGCCTATT GTCGATGTGC TGCACCGCTT


 


1101
CCCGGCAAGC CTGACGGCAG AACAATTCAT CCGTTTACTG CGTCCGCTTG


 


1151
CACCCCGTTT GTATTCGATT TCTTCAGCAC AGGCGGAAGT GGGCGATGAA


 


1201
GTGCATTTAA CTGTCGGCGT GGTTCGTTTT GAACACGAAG GCCGCGCCAG


 


1251
AACGGGCGGC GCATCGGGTT TCCTTGCCGA CCGGCTGGAA GAGGACGGCA


 


1301
CGGTGCGCGT GTTTGTGGAA CGCAACGACG GCTTCAGGCT GCCCGAAGAC


 


1351
AGCCGCAAGC CGATTGTGAT GATCGGCTCG GGCACCGGCG TCGCACCGTT


 


1401
CCGCGCTTTC GTCCAACAAC GTGCCGCAGA AAATGCGGAA GGCAAAAACT


 


1451
GGCTGATTTT CGGCAATCCG CATTTTGCCC GTGATTTTCT CTATCAAACC


 


1501
GAATGGCAGC AGTTTGCCAA AGACGGCTTC CTGCACAGGT ACGATTTCGC


 


1551
CTGGTCCCGC GATCAGGAAG AAAAAATCTA TGTGCAGGAC AAAATCCGCG


 


1601
AACAGGCGGA AGGACTTTGG CAATGGCTGC AGGAAGGCGC GCATATCTAT


 


1651
GTGTGCGGCG ATGCGGCAAA AATGGCAAAA GACGTGGAAG CCGCCTTGCT


 


1701
GGATGTGATT ATCGGGGCAG GACATTTGGA CGAAGAGGGC GCAGAAGAAT


 


1751
ATTTGGATAT GCTGCGCGAA GAAAAACGCT ATCAGCGTGA TGTTTATTGA






This corresponds to the amino acid sequence <SEQ ID 610; ORF 150>:










m150.pep




1
MQNTNPPLPP LPPEITQLLS GLDAAQWAWL SGYAWAKAGN GASAGLPALQ



 


51
TALPAAEPFS VTVLSASQTG NAKSVADKAA DSLEAAGIQV SRAELKDYKA


 


101
KNIAGERRLL LVTSTQGEGE PPKEAVVLHK LLNGKKAPKL DKLQFAVLGL


 


151
GDSSYPNFCQ AGKDFDRRFE ELGAKRLLER VDADLDFTAS ANAWTDNIAA


 


201
LLKEEAAKNR ATPAPQTTPP AGLQTAPDGR YCKAAPFPAA LLANQKITAR


 


251
QSDKDVRHIE IDLSGSDLHY LPGDALGVWF DNDPALVREI LDLLGIDPAT


 


301
EIQAGGKMMP VARALSSHFE LTQNTPAFVK GYAAFAHYEE LDKIIADNAV


 


351
LQDFVQNTPI VDVLHRFPAS LTAEQFIRLL RPLAPRLYSI SSAQAEVGDE


 


401
VHLTVGVVRF EHEGRARTGG ASGFLADRLE EDGTVRVFVE RNDGFRLPED


 


451
SRKPIVMIGS GTGVAPFRAF VQQRAAENAE GKNWLIFGNP HFARDFLYQT


 


501
EWQQFAKDGF LHRYDFAWSR DQEEKIYVQD KIREQAEGLW QWLQEGAHIY


 


551
VCGDAAKMAK DVEAALLDVI IGAGHLDEEG AEEYLDMLRE EKRYQRDVY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 150 shows 91.3% identity over a 369 as overlap with a predicted ORF (ORF 150.ng) from N. gonorrhoeae: 

m150/g150




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 611>:










a150.seq




1
ATGCAGAACA CAAATCCGCC ATTACCGCCT ATGCCGCCCG AAATCACGCA


 


51
GCTCCTGTCG GGGCTGGACG CGGCACAATG GGCGTGGCTG TCCGGCTACG


 


101
CTTGGGCAAA AGCAGGAAAC GGGGCATCTG CAGGACTGCC CGCGCTTCAG


 


151
ACGGCATTGC CGACGGCAGA ACCTTTTTCC GTAACCGTCC TTTCCGCCTC


 


201
GCAAACCGGC AATGCGAAAT CCGTTGCCGA CAAAGCGGCG GACAGCCTGG


 


251
AAGCCGCCGG CATCCAAGTC AGTCGCGCCG AACTGAAAGA CTATAAGGCG


 


301
AAAAACATCG CCGGCGAACG CCGCCTGCTG CTGGTTACCT CCACCCAAGG


 


351
CGAAGGCGAA CCGCCGGAAG AAGCCGTCGT GCTGCACAAA CTGCTGAACG


 


401
GCAAAAAAGC CCCGAAATTG GACAAACTCC AATTTGCCGT ACTGGGTTTG


 


451
GGCGACAGCT CCTATCCGAA TTTCTGCCGG GCGGGCAAAG ATTTCGACAA


 


501
ACGTTTTGAA GAATTGGGCG CAAAACGCCT GCTCGAACGC GTTGATGCGG


 


551
ATTTGGACTT TGCCGCCGCC GCAGACGGAT GGACAGATAA TATCGCCGCA


 


601
CTCTTAAAAG AAGAAGCCGC AAAAAACCGG GCAACGCCCG CGCCGCAGAC


 


651
AACGCCCCCC GCCGGCCTTC AGACGGCACC GGATGGCAGG TACTGCAAGG


 


701
CAGACCCCTT TGCCGCCGCC CTGCTGGCCA ATCAGAAAAT CACCGCCCGC


 


751
CAATCCGATA AAGACGTGCG CCACATCGAA ATCGATTTGA GCGGTTCGGA


 


801
TTTGCACTAC CTCCCGGGCG ACGCGCTCGG CGTTTGGTTT GACAACGATC


 


851
CGGCACTGGT CAGGGAAATC CTAGACCTGC TCGGCATCGA TCAGGCAACG


 


901
GAAATACAGG CGGGCGGAAA AACCCTGCCG GTTGCCTCCG CACTGTTATC


 


951
CCATTTTGAA CTCACGCAAA ACACCCCCGC CTTTGTCAAA GGCTATGCCC


 


1001
CGTTCGCCGA TGATGACGAA CTCGACCGTA TTGCTGCCGA CAACGCCGTT


 


1051
TTGCAAGGCT TTGTGCAAAG CACGCCGATT GCCGATGTGC TGCACCGCTT


 


1101
CCCGGCAAAA CTGACAGCGG AACAATTCGC CGGCCTACTG CGCCCGCTTG


 


1151
CGCCGCGCCT GTATTCGATT TCCTCGTCGC AGGCGGAAGT GGGGGACGAA


 


1201
GTGCACCTGA CCGTCGGCGC GGTGCGTTTC GAACACGAAG GGCGCGCCAG


 


1251
GGCGGGCGGC GCATCGGGTT TCCTTGCCGA CCGGCTGGAA GAGGACGGCA


 


1301
CGGTGCGCGT GTTTGTGGAA CGCAACGACG GCTTCAGGCT GCCCGAAGAC


 


1351
AGCCGCAAGC CGATTGTGAT GATCGGCTCG GGCACCGGCG TCGCACCGTT


 


1401
CCGCGCTTTC GTCCAACAAC GTGCCGCAGA AAATGCGGAA GGCAAAAACT


 


1451
GGCTGTTTTT CGGCAATCCG CATTTTGCCC GTGATTTTCT CTATCAAACC


 


1501
GAATGGCAGC AGTTTGCCAA AGACGGCTTC CTGCACAGAT ACGATTTCGC


 


1551
CTGGTCGCGC GATCAGGAAG AAAAAATCTA TGTGCAGGAC AAAATCCGCG


 


1601
AACAGGCGGA AGGACTTTGG CAATGGCTGC AGGAAGGCGC GCATATCTAT


 


1651
GTGTGCGGCG ATGCGGCAAA AATGGCAAAA GACGTGGAAG CCGCCTTGCT


 


1701
GGATGTGATT ATCGGGGCAG GACATTTGGA CGAAGAGGGC GCAGAAGAAT


 


1751
ATTTGGATAT GCTGCGCGAA GAAAAACGCT ATCAGCGTGA TGTTTATTGA






This corresponds to the amino acid sequence <SEQ ID 612; ORF 150.a>:










a150.pep




1
MQNTNPPLPP MPPEITQLLS GLDAAQWAWL SGYAWAKAGN GASAGLPALQ


 


51
TALPTAEPFS VTVLSASQTG NAKSVADKAA DSLEAAGIQV SRAELKDYKA


 


101
KNIAGERRLL LVTSTQGEGE PPEEAVVLHK LLNGKKAPKL DKLQFAVLGL


 


151
GDSSYPNFCR AGKDFDKRFE ELGAKRLLER VDADLDFAAA ADGWTDNIAA


 


201
LLKEEAAKNR ATPAPQTTPP AGLQTAPDGR YCKADPFPAA LLANQKITAR


 


251
QSDKDVRHIE IDLSGSDLHY LPGDALGVWF DNDPALVREI LDLLGIDQAT


 


301
EIQAGGKTLP VASALLSHFE LTQNTPAFVK GYAPFADDDE LDRIAADNAV


 


351
LQGFVQSTPI ADVLHRFPAK LTAEQFAGLL RPLAPRLYSI SSSQAEVGDE


 


401
VHLTVGAVRF EHEGRARAGG ASGFLADRLE EDGTVRVFVE RNDGFRLPED


 


451
SRKPIVMIGS GTGVAPFRAF VQQRAAENAE GKNWLFFGNP HFARDFLYQT


 


501
EWQQFAKDGF LHRYDFAWSR DQEEKIYVQD KIREQAEGLW QWLQEGAHIY


 


551
VCGDAAKMAK DVEAALLDVI IGAGHLDEEG AEEYLDMLRE EKRYQRDVY*






m150/a150 94.8% identity in 599 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 613>:










g151.seq




1
ATGAAACAAA TCCGCAACAT CGCCATCATC GCACACGTCG ACCACGGCAA


 


51
AACCACATTG GTCGACCAAC TGCTGCGCCA ATCCGGCACA TTCCGCGCCA


 


101
ACCAGCAGGT TGACGAGCGC GTGATGGACA GCAACGACCT TGAAAAAGAA


 


151
CGCGGCATCA CCATCCTCGC CAAAAACACC GCCATCGATT ACGAAGGCTG


 


201
CCACATCAAT ATCGTCGACA CGCCGGGACA CGCCGACTTC GGCGGCGAAG


 


251
TGGAGCGCGT TTTGGGGATG GTGGATTGCG TCGTCTTGTT GGTGGACGCA


 


301
CAGGAAGGTC CGATGCCGCA AACCCGTTTC GTGACCAAAA AAGCCTTGGC


 


351
TTTGGGGCTG AAACCGATTG TCGTCATCAA CAAAATCGAC AAACCGTCCG


 


401
CCCGTCCGAG CTGGGTTATC GACCAGACTT TCGAGTTGTT CGACAACTTG


 


451
GGTGCGACCG ACGAGCAGTT GGATTTCCCG ATTGTTTACG CTTCAGGTTT


 


501
GAGCGGCTTT GCCAAGCTGG AAGAAAccga CGAGAGCAGC GATATGCGCC


 


551
CGCtgttcgA CACCATCCTA AAATACAcgc ctgCACCGAG CGGCAGCGCG


 


601
GACGAGCCGC TGCAACTGCA AATTTCCCAA CTCGACTACG ACAACTACAC


 


651
CGGCCGCCTC GGTATCGGTC GTATCTTGAA CGGACGCATC AAACCCGGCC


 


701
AAACCGTTGC CGTGATGAAC CACGAGCAGC AAATCGCCCA AGGCCGCATC


 


751
AACCAGCTTT TGGGTTTCAA AGGCTTGGAA CGCGTGCCGC TTGAAGAAGC


 


801
CGAAGCCGGC GACATTGTGA TTATTTCCGG TATCGAAGAC ATCGGCATCG


 


851
GCGTAACCAT CACCGACAAA GACAACCCCA AAGGCCTGCC GATGTTGAGC


 


901
GTGGACGAAC CGACGCTGAC GATGGACTTT ATGGTAAACA CCAGCCCGCT


 


951
CGCAGGTACA GAAGGCAAAT TCGTGACCAG CCGCCAAATC CGCGACCGCC


 


1001
TGCAAAAAGA ATTGCTGACC AACGTTGCCC TGCGCGTGGA AGACACCGCC


 


1051
GatgCCGACG TGTTCCGCGT ATCcgGGCGC GGCGAACTGC ACCTGACGAT


 


1101
TTTGCTGGAA AATATGCGCC GCGAAGGCTA CGAACTCGCC GTCGGCAAGC


 


1151
CGCGCGTCGT GTACCGAGAC ATCGACGGTC AAAAATGCGA ACCTTATGAA


 


1201
AACCTGACTG TGGACGTACc cgacgacAAC CAAGGCGCGG TAATGGAAGA


 


1251
ACTCGGCCGC CGCCGTGGCG AACTGACCAA TATGGAAAGC GACGGCAACG


 


1301
GacgCACCCG CCTCGAATAC CATATTCCAG CGCGCGGCTT GATCGGTTTC


 


1351
CAAGGCGAAT TCATGACCCT GACGCGCGGC GTCGGGCTGA TGAgccacGT


 


1401
GTTcgacgac tacgcgcccg tcaAACCCGA TATGCCCGGC CGCCACAACG


 


1451
GCGTactggt GtcccaAGAG CAGGGCGAGG CGGTTGCTTA CGCCTTGTGG


 


1501
AATCTTGAAG ACCGCGGCCG TATGTTCGTA TCGCCCAACG ACAAAATCTA


 


1551
CGAAGGTATG ATTATCGGCA TCCACAGCCG CGACAACGAT TTGGTGGTCA


 


1601
ACCCGCTCAA AGGCAAAAAA CTCACCAATA TCCGTGCCAG CGGTACCGAC


 


1651
GAAGCGGTGC GCCTGACCAC GCCGATCAAA CTGAcgcTGG AAGGCGCGGT


 


1701
CGAGTTTATC GACGATGACG AGCTGGTGGA AATCACGCCG CAAtccatcc


 


1751
gcctgcgcat gcgttacctG AGCGaattgg aacgccgccg tcaTTTTAAA


 


1801
AagctgGATT AA






This corresponds to the amino acid sequence <SEQ ID 614; ORF 151.ng>:










g151.pep




1
MKQIRNIAII AHVDHGKTTL VDQLLRQSGT FRANQQVDER VMDSNDLEKE


 


51
RGITILAKNT AIDYEGCHIN IVDTPGHADF GGEVERVLGM VDCVVLLVDA


 


101
QEGPMPQTRF VTKKALALGL KPIVVINKID KPSARPSWVI DQTFELFDNL


 


151
GATDEQLDFP IVYASGLSGF AKLEETDESS DMRPLFDTIL KYTPAPSGSA


 


201
DEPLQLQISQ LDYDNYTGRL GIGRILNGRI KPGQTVAVMN HEQQIAQGRI


 


251
NQLLGFKGLE RVPLEEAEAG DIVIISGIED IGIGVTITDK DNPKGLPMLS


 


301
VDEPTLTMDF MVNTSPLAGT EGKFVTSRQI RDRLQKELLT NVALRVEDTA


 


351
DADVFRVSGR GELHLTILLE NMRREGYELA VGKPRVVYRD IDGQKCEPYE


 


401
NLTVDVPDDN QGAVMEELGR RRGELTNMES DGNGRTRLEY HIPARGLIGF


 


451
QGEFMTLTRG VGLMSHVFDD YAPVKPDMPG RHNGVLVSQE QGEAVAYALW


 


501
NLEDRGRMFV SPNDKIYEGM IIGIHSRDND LVVNPLKGKK LTNIRASGTD


 


551
EAVRLTTPIK LTLEGAVEFI DDDELVEITP QSIRLRMRYL SELERRRHFK


 


601
KLD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 615>:










m151.seq




1
ATGAAACAAA TCCGCAACAT CGCCATCATC GCCCACGTCG ACCACGGCAA


 


51
AACCACATTG GTCGACCAAC TGCTGCGCCA ATCCGGCACA TTCCGCGCCA


 


101
ACCAGCAGGT TGACGAGCGC GTGATGGACA GCAACGACCT TGAAAAAGAA


 


151
CGCGGCATCA CCATCCTCGC CAAAAACACC GCCATCGATT ACGAAGGCTA


 


201
CCACATCAAT ATCGTCGACA CGCCGGGACA CGCCGACTTC GGCGGCGAAG


 


251
TAGAGCGCGT TTTGGGGATG GTGGACTGCG TCGTCTTGTT GGTGGACGCG


 


301
CAGGAAGGCC CGATGCCGCA AACCCGTTTC GTGACCAAAA AAGCCTTGGC


 


351
TTTGGGGCTG AAACCGATTG TCGTCATCAA CAAAATCGAC AAGCCGTCCG


 


401
CTCGTCCGAG CTGGGTTATC GACCAAACTT TCGAGCTGTT CGACAACTTG


 


451
GGCGCGACCG ACGAGCAGTT GGATTTCCCG ATTGTTTACG CTTCAGGGTT


 


501
GAGCGGTTTC GCCAAATTGG AAGAAACCGA CGAGAGCAAC GACATGCGTC


 


551
CGCTGTTCGA TACTATCTTA AAATATACGC CTGCACCGAG CGGCAGCGCG


 


601
GACGAAACGC TGCAACTGCA AATTTCCCAA CTCGACTACG ACAACTACAC


 


651
CGGCCGCCTC GGTATCGGTC GTATCTTGAA CGGACGCATC AAACCCGGCC


 


701
AAACCGTTGC CGTCATGAAC CACGATCAGC AAATCGCCCA AGGCCGCATC


 


751
AACCAGCTTT TGGGTTTCAA AGGTTTGGAA CGCGTGCCGC TTGAAGAAGC


 


801
CGAAGCCGGC GACATCGTGA TTATTTCCGG TATCGAAGAC ATCGGTATCG


 


851
GCGTAACCAT CACCGACAAA GACAATCCCA AAGGCCTACC GATGTTGAGC


 


901
GTGGACGAAC CGACGCTGAC GATGGACTTT ATGGTCAACA CCAGCCCGCT


 


951
GGCGGGTACG GAAGGCAAAT TCGTAACCAG CCGCCAAATC CGCGACCGCC


 


1001
TGCAAAAAGA ATTGCTGACC AACGTCGCCC TGCGCGTGGA AGATACCGCC


 


1051
GATGCCGACG TGTTCCGCGT ATCCGGGCGC GGCGAGCTGC ACCTGACCAT


 


1101
TTTGCTGGAA AACATGCGCC GCGAAGGCTA CGAACTCGCC GTCGGCAAAC


 


1151
CGCGCGTCGT GTACCGCGAC ATCGACGGTC AAAAATGCGA ACCGTATGAA


 


1201
AACCTGACCG TGGATGTACC CGACGACAAC CAAGGCGCGG TAATGGAAGA


 


1251
ACTCGGCCGC CGCCGTGGCG AACTGACTAA TATGGAAAGC GACGGCAACG


 


1301
GACGCACCCG CCTCGAATAC CATATTCCAG CGCGCGGCTT GATCGGTTTC


 


1351
CAAGGCGAAT TTATGACCCT GACGCGCGGG GTCGGGCTGA TGAGCCACGT


 


1401
GTTCGACGAT TACGCGCCCG TCAAACCCGA TATGCCCGGC CGCCACAACG


 


1451
GCGTGCTGGT GTCCCAAGAG CAGGGCGAGG CAGTCGCTTA CGCCTTGTGG


 


1501
AATCTGGAAG ACCGCGGCCG TATGTTCGTA TCGCCCAACG ACAAAATCTA


 


1551
CGAAGGCATG ATTATCGGCA TCCACAGTCG CGACAACGAT TTGGTGGTCA


 


1601
ACCCGCTCAA AGGCAAAAAA CTTACCAACA TCCGTGCCAG CGGTACCGAC


 


1651
GAAGCCGTTC GCCTGACCAC GCCAATCAAG CTGACGCTGG AAGGTGCGGT


 


1701
TGAGTTTATC GACGATGACG AACTCGTTGA AATCACGCCG CAATCCATCC


 


1751
GTCTGCGCAA GCGTTACTTG AGCGAATTGG AACGCCGCCG CCACTTTAAA


 


1801
AAGCTGGATT GA






This corresponds to the amino acid sequence <SEQ ID 616; ORF 151>:










m151.pep




1
MKQIRNIAII AHVDHGKTTL VDQLLRQSGT FRANQQVDER VMDSNDLEKE


 


51
RGITILAKNT AIDYEGYHIN IVDTPGHADF GGEVERVLGM VDCVVLLVDA


 


101
QEGPMPQTRF VTKKALALGL KPIVVINKID KPSARPSWVI DQTFELFDNL


 


151
GATDEQLDFP IVYASGLSGF AKLEETDESN DMRPLFDTIL KYTPAPSGSA


 


201
DETLQLQISQ LDYDNYTGRL GIGRIINGRI KPGQTVAVMN HDQQIAQGRI


 


251
NQLLGFKGLE RVPLEEAEAG DIVIISGIED IGIGVTITDK DNPKGLPMLS


 


301
VDEPTLTMDF MVNTSPLAGT EGKFVTSRQI RDRLQKELLT NVALRVEDTA


 


351
DADVFRVSGR GELHLTILLE NMRREGYELA VGKPRVVYRD IDGQKCEPYE


 


401
NLTVDVPDDN QGAVMEELGR RRGELTNMES DGNGRTRLEY HIPARGLIGF


 


451
QGEFMTLTRG VGLMSHVFDD YAPVKPDMPG RHNGVLVSQE QGEAVAYALW


 


501
NLEDRGRMFV SPNDKIYEGM IIGIHSRDND LVVNPLKGKK LTNIRASGTD


 


551
EAVRLTTPIK LTLEGAVEFI DDDELVEITP QSIRLRKRYL SELERRRHFK


 


601
KLD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 151 shows 99.2% identity over a 603 aa overlap with a predicted ORF (ORF 151.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 617>:










a151.seq




1
ATGAAACAAA TCCGCAACAT CGCCATCATC GCCCACGTCG ACCACGGCAA


 


51
AACCACATTG GTCGACCAAC TGCTGCGCCA ATCCGGCACA TTCCGCGCCA


 


101
ACCAGCAGGT TGACGAGCGC GTGATGGACA GCAACGACCT TGAAAAAGAA


 


151
CGCGGCATCA CCATCCTCGC CAAAAACACC GCCATCGATT ACGAAGGCTA


 


201
CCACATCAAT ATCGTCGACA CGCCGGGACA CGCCGACTTC GGCGGCGAAG


 


251
TAGAGCGAGT TTTGGGGATG GTGGACTGCG TCGTCTTGTT GGTGGACGCG


 


301
CAGGAAGGCC CGATGCCGCA AACCCGTTTC GTGACCAAAA AAGCCTTGGC


 


351
TTTGGGGCTG AAACCGATTG TCGTCATCAA TAAAATCGAC AAACCGTCCG


 


401
CCCGTCCGAG CTGGGTCATC GACCAAACTT TCGAGCTGTT CGACAACTTG


 


451
GGCGCGACCG ACGAGCAGTT GGATTTCCCG ATTGTTTATG CTTCCGGTCT


 


501
GTCCGGTTTC GCCAAATTGG AAGAAACCGA CGAGAGCAAC GACATGCGTC


 


551
CGCTGTTCGA TACTATCTTA AAATATACGC CTGCACCGAG CGGCAGCGCG


 


601
GACGAAACGC TGCAACTGCA AATTTCCCAA CTCGACTACG ACAACTACAC


 


651
CGGCCGCCTC GGTATCGGTC GTATCTTGAA CGGACGTATC AAGCCCGGTC


 


701
AAGTTGTTGC CGTCATGAAC CACGATCAAC AAATCGCCCA AGGCCGCATC


 


751
AACCAGCTTT TGGGTTTCAA AGGTTTAGAA CGCGTGCCGC TTGAAGAAGC


 


801
CGAAGCCGGC GACATCGTGA TTATTTCCGG TATTGAAGAC ATCGGCATCG


 


851
GCGTAACCAT CACCGACAAA GACAACCCCA AAGGCCTGCC GATGTTGAGC


 


901
GTGGACGAAC CGACGCTGAC GATGGACTTT ATGGTCAACA CCAGCCCGTT


 


951
GGCAGGTACG GAAGGCAAAT TCGTAACCAG CCGCCAAATC CGCGACCGCC


 


1001
TGCAAAAAGA ATTGCTGACC AACGTCGCCC TGCGCGTGGA AGATACCGCC


 


1051
GATGCCGACG TGTTCCGCGT ATCCGGGCGC GGCGAGCTGC ACCTGACCAT


 


1101
TTTGCTGGAA AACATGCGCC GCGAAGGCTA CGAACTCGCC GTCGGCAAAC


 


1151
CGCGCGTCGT GTACCGCGAC ATCGACGGTC AAAAATGCGA ACCGTATGAA


 


1201
AACCTGACCG TGGACGTACC CGACGACAAC CAAGGCGCGG TAATGGAAGA


 


1251
ACTCGGCCGC CGCCGTGGCG AACTGACTAA TATGGAAAGC GACGGCAACG


 


1301
GACGCACCCG CCTCGAATAC CATATTCCAG CGCGCGGCTT GATCGGCTTC


 


1351
CAAGGCGAAT TTATGACCCT GACGCGCGGG GTCGGGCTGA TGAGCCACGT


 


1401
GTTCGACGAT TACGCGCCCG TCAAACCCGA TATGCCTGGC CGCCACAACG


 


1451
GCGTGCTGGT GTCCCAAGAG CAGGGCGAGG CAGTCGCTTA CGCCTTGTGG


 


1501
AATCTGGAAG ACCGCGGCCG TATGTTCGTA TCGCCCAACG ACAAAATCTA


 


1551
CGAAGGTATG ATTATCGGCA TCCACAGTCG CGACAACGAT TTGGTGGTCA


 


1601
ACCCGCTCAA AGGCAAAAAA CTTACCAACA TCCGTGCCAG CGGTACCGAC


 


1651
GAAGCCGTTC GCCTGACCAC GCCGATTAAG CTGACGCTGG AAGGTGCGGT


 


1701
CGAGTTTATC GACGATGATG AGCTGGTAGA AATCACGCCG CAATCCATCC


 


1751
GTCTGCGCAA GCGTTACTTG AGCGAATTGG AACGCCGCCG CCATTTCAAA


 


1801
AAGCTAGATT GA






This corresponds to the amino acid sequence <SEQ ID 618; ORF 151.a>:










a151.pep




1
MKQIRNIAII AHVDHGKTTL VDQLLRQSGT FRANQQVDER VMDSNDLEKE


 


51
RGITILAKNT AIDYEGYHIN IVDTPGHADF GGEVERVLGM VDCVVLLVDA


 


101
QEGPMPQTRF VTKKALALGL KPIVVINKID KPSARPSWVI DQTFELFDNL


 


151
GATDEQLDFP IVYASGLSGF AKLEETDESN DMRPLFDTIL KYTPAPSGSA


 


201
DETLQLQISQ LDYDNYTGRL GIGRILNGRI KPGQVVAVMN HDQQIAQGRI


 


251
NQLLGFKGLE RVPLEEAEAG DIVIISGIED IGIGVTITDK DNPKGLPMLS


 


301
VDEPTLTMDF MVNTSPLAGT EGKFVTSRQI RDRLQKELLT NVALRVEDTA


 


351
DADVFRVSGR GELHLTILLE NMRREGYELA VGKPRVVYRD IDGQKCEPYE


 


401
NLTVDVPDDN QGAVMEELGR RRGELTNMES DGNGRTRLEY HIPARGLIGF


 


451
QGEFMTLTRG VGLMSHVFDD YAPVKPDMPG RHNGVLVSQE QGEAVAYALW


 


501
NLEDRGRMFV SPNDKIYEGM IIGIHSRDND LVVNPLKGKK LTNIRASGTD


 


551
EAVRLTTPIK LTLEGAVEFI DDDELVEITP QSIRLRKRYL SELERRRHFK


 


601
KLD*






m151/a151 99.8% identity in 603 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 619>:










g152.seq




1
ATGAAAAaca aAACCaaagt ctgGGacttc cCcacccgcc ttTTCCactG


 


51
GctgcttgCC gCATCCctgc CCTTTATGTG gtatagCGCA AAAGCCGGCG


 


101
GcgataTGCT GcaatgGCAC ACGCGCGTCG GGCTGCTCGT CCTTTTCCTG


 


151
CTCGTATTCC GCCTCTGCTG GGGCATTTGG GGCAgcgATA CCGCCCGTTT


 


201
CTCccgTtTC GTCCGAGGTT GGGCAGGTAT ACGCGGCTAT CTGAAAAAcg


 


251
gCATTCCCGA ACAtatcCAG CCCGGACACA ACCCCTTGGG CGCACTgatg


 


301
gtcGTTGCGC TTTTGgccgc cgtcTCATTT CAagtcggcA CGGGGCTTTT


 


351
Tgccgccaat gaaaacacct tcagcaCCAa cggctacctc aaccatttgg


 


401
tttccgaaca tacgGGCAGC CTTATACGGA AAATCCACCT CAACTTTTTC


 


451
AAGCTGCTCG CCGTTTTTTC CGCAGTCCAC ATCGCCGCCG TCGCCGCATA


 


501
CCGCATATTC AAAAAGAAAA ACCTCGTCCG CCCGATGATA ACCGGCTTCA


 


551
AATACATCGA AGGCAAAACC TCAATCCGCT TTGCCGGCAA AGCCGCGCTT


 


601
GCCGCCGCAT TATCGGTTGC CGCGCTTGCC GCAGCCGCCA TCCTGCTCCT


 


651
GTCCTGA






This corresponds to the amino acid sequence <SEQ ID 620; ORF 152.ng>:










g152.pep




1
MKNKTKVWDF PTRLFHWLLA ASLPFMWYSA KAGGDMLQWH TRVGLLVLFL


 


51
LVFRLCWGIW GSDTARFSRF VRGWAGIRGY LKNGIPEHIQ PGHNPLGALM


 


101
VVALLAAVSF QVGTGLFAAN ENTFSTNGYL NHLVSEHTGS LIRKIHLNFF


 


151
KLLAVFSAVH IAAVAAYRIF KKKNLVRPMI TGFKYIEGKT SIRFAGKAAL


 


201
AAALSVAALA AAAILLLS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 621>:










m152.seq




1
ATGAAAAACA AAACCAAAGT CTGGGACCTC CCCACCCGCC TTTTCCACTG


 


51
GCTGCTTGCC GCGTCCCTGC CCTTTATGTG GTATAGCGCG AAAGCCGGCG


 


101
GCGATATGCT GCAATGGCAC ACGCGCGTCG GGCTGTTCGT CCTTTTCCTG


 


151
CTCGTATTTC GCCTCTGCTG GGGCATTTGG GGCAGCGATA CCGCCCGTTT


 


201
TTCCCGTTTC GTCCAAGGCT GGGCAGGCAT ACGCGGCTAT CTGAAAAACG


 


251
GTATTCCCGA ACACATCCAG CCCGGACACA ACCCCTTGGG CGCACTGATG


 


301
GTCGTTGCGC TTTTGGCCGC CGTGTCCTTC CAAGTCGGCA CCGGGCTTTT


 


351
TGCCGCCGAT GAAAACACCT TCAGCACCAA CGGCTACCTC AACCATTTGG


 


401
TTTCCGAACA TACGGGCAGC CTTATGCGGA AAATCCACCT CAACTTTTTC


 


451
AAGCTGCTCG CCGTTTTTTC TGCAATCCAC ATCGCCGCCG TCGCCGCATA


 


501
CCGCGTATTC AAAAAGAAAA ACCTCATCCT CCCGATGATA ACCGGCTTCA


 


551
AATACATCGA AGGCAAAACC TCAATCCGCT TTGCAGGCAA AGCCGCGCTT


 


601
GCCGCCGCAT TATCGGTTGC CTCGCTTGCC GCAGCCGCCA TCCTGCTCCT


 


651
GTCCTGA






This corresponds to the amino acid sequence <SEQ ID 622; ORF 152>:










m152.pep




1
MKNKTKVWDL PTRLFHWLLA ASLPFMWYSA KAGGDMLQWH TRVGLFVLFL


 


51
LVFRLCWGIW GSDTARFSRF VQGWAGIRGY LKNGIPEHIQ PGHNPLGALM


 


101
VVALLAAVSF QVGTGLFAAD ENTFSTNGYL NHLVSEHTGS LMRKIHLNFF


 


151
KLLAVFSAIH IAAVAAYRVF KKKNLILPMI TGFKYIEGKT SIRFAGKAAL


 


201
AAALSVASLA AAAILLLS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 152 shows 95.4% identity over a 218 aa overlap with a predicted ORF (ORF 152.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 623>:










a152.seq




1
ATGAAAAACA AAACCAAAGT CTGGGACTTC CCCACCCGCC TTTTCCACTG


 


51
GCTGCTTGCC GCATCCCTAC CCTTTATGTG GTATAGCGCG AAAACCGGCG


 


101
GCGATATGCT GCAATGGCAC ACGCGCGTCG GGCTGTTTAT CCTTTTCCTG


 


151
CTCGTATTCC GCCTCTGCTG GGGCATTTGG GGCAGCGATA CCGCCCGTTT


 


201
CTCCCGTTTC GTCCGCGGAT GGTCGGGTAT CAGAGAGTAT ATGAAAAACG


 


251
GTATTCCCGA ACACGTCCAA CCCGGACACA ACCCCTTGGG CGCACTGATG


 


301
GTCGTTGCGC TTTTGGCCGC CGTGTCGTTC CAAGTCGGCA CAGGGCTTTT


 


351
TGCCGCCGAT GTAAACACCT TCAGCACCAA CGGCTACCTC AACCATTTGG


 


401
TTTCCGAACA TACGGGCAGC CTTATGCGGA AAATCCATCT CAACTTTTTC


 


451
AAACTGCTCG CCGTTTTTTC CGCAGTCCAC ATCGCCGNCG TCGCCGCATA


 


501
CCGCGTGTTC AAAAAGAAAA ACCTCGTCCT CCCGATGATA ACCGGCTTCA


 


551
AATACATCGA AGGCAAAACC TCAATCCGCT TTGCCGGCAA AGCCGCGCTT


 


601
GCCGCCGCAT TATCGGTTGC CGCGCTTGCC GCAGCCGCCA TCCTGCTCCT


 


651
GTCCTGA






This corresponds to the amino acid sequence <SEQ ID 624; ORF 152.a>:










a152.pep




1
MKNKTKVWDF PTRLFHWLLA ASLPFMWYSA KTGGDMLQWH TRVGLFILFL


 


51
LVFRLCWGIW GSDTARFSRF VRGWSGIREY MKNGIPEHVQ PGHNPLGALM


 


101
VVALLAAVSF QVGTGLFAAD VNTFSTNGYL NHLVSEHTGS LMRKIHLNFF


 


151
KLLAVFSAVH IAXVAAYRVF KKKNLVLPMI TGFKYIEGKT SIRFAGKAAL


 


201
AAALSVAALA AAAILLLS*






m152/a152 94.0% identity in 218 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 625>:










g153.seq




1
atggggtttg cttaCAgtat gacgtatatc gaggtCGGGa taccggaggc


 


51
ggcatccgtc ctttCgctGC CCGAGATgat gcgcctgatG GTGTTtCagg


 


101
attATGGTTT TttggcCGAA GTGATGTTTG TGctgaCTTT cGGCGcgcCG


 


151
GTTCTGTTtC TGCTGCTGTG CCTGTATGTC TATGCCGCGC TGATACGGAA


 


201
ACAGGCGTAT CCTGCGCTGC GTTTGGCAAC GCGTGTGATG GTGCGCTTGA


 


251
GGCAGGCGAT GATGGTGGAT GTGTTTTTTG TTTCCACTCT GGTGGCGTAT


 


301
ATCAAGCTCT CGTCTGTGGC AAAGGTTCGC TTCGGGCCGG CGTTTTATCT


 


351
GATGTTCGCG CTGTCGGTTA TGCTGATTCG GACTTCGGTA TCGGTTCCCC


 


401
AGCATTGGGT GTATTTCCAA ATCGGGCGGC TGACGGGGAA TAATGCGGTT


 


451
CAGACGGCAT CGGAAGGCAA AACCTGTTGC AGCCGCTGCC TGTATTTccg


 


501
cgacAGTgcc gaatccCCCT GCGGGGTGTg cgGCGcggaA CTgtacggcg


 


551
gacggccgaa aagtCTGAGt atttCgtCGG CGTTTCTgac ggcggcggTT


 


601
GTTTTGTATT TCCctgCcaa TATCctgccg attaTGAttt cgtccAATCc


 


651
tgccgccacg GAGGcCAACA CCATCTTTAG CGGCATCGCT TATATGTGGG


 


701
ACGagggcgA CAGGCTGATT GCGGCGGTTA TTTTCAGCGC GAGTATTTTG


 


751
GTGCCGGTGC TGAAGATTGC GGCAATGTCG GTTTTGATTG CGGCGGCACG


 


801
GTTCGCTTTG CCGGCGGGCG CAAAGAAATT GTCGCACCTC tacCGCATCA


 


851
CCGAAGCGGT CGGCCGCTGG TCGATGATTG ATATTTTTGT GATTATTATT


 


901
TTGATGTGTT CGTTCCacaC TTATGCCGCG CGCGTCATTC CGGGCAGTGC


 


951
GGCAGTCTAT TTCTGCCTGG TCGTGATTTT GACGATGCTG TCCGCCTATT


 


1001
ATTTCGACCC GCGCCTGCTT TGGGACAAAC GCGCTTCAGA CGGCATTGCT


 


1051
TTCAACGAAA CGGAAAAATA TGACTGA






This corresponds to the amino acid sequence <SEQ ID 626; ORF 153.ng>:










g153.pep




1
MGFAYSMTYI EVGIPEAASV LSLPEMMRLM VFQDYGFLAE VMFVLTFGAP


 


51
VLFLLLCLYV YAALIRKQAY PALRLATRVM VRLRQAMMVD VFFVSTLVAY


 


101
IKLSSVAKVR FGPSAFYLMFA LSVMLIRTSV SVPQHWVYFQ IGRLTGNNAV


 


151
QTASEGKTCC SRCLYFRDSA ESPCGVCGAE LYGGRPKSLS ISSAFLTAAV


 


201
VLYFPANILP IMISSNPAAT EANTIFSGIA YMWDEGDRLI AAVIFSASIL


 


251
VPVLKIAAMS VLIAAARFAL PAGAKKLSHL YRITEAVGRW SMIDIFVIII


 


301
LMCSFHTYAA RVIPGSAAVY FCLVVILTML SAYYFDPRLL WDKRASDGIA


 


351
FNETEKYD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 627>:










m153.seq




1
ATGGCGTTTG CTTACGGTAT GACGTATATC GAGGTCGGGA TACCGGGTGC


 


51
GGCATCCGTC CTTTCGCTGC CCGAGATGAT GCGCCTGATG GTGTTTCAGG


 


101
ATTATGGTTT TTTGGCCGAA GTGATGTTTG TGCTGACTTT CGGCGCGCCG


 


151
GTTCTGTTTC TGCTGCTGTG CCTGTATGTC TATGCCGCGC TGATACGGAA


 


201
ACAGGCGTAT CCTGCGCTGC GTTTGGCAAC GCGTGTGATG GTGCGCTTGA


 


251
GACAGGCGAT GATGGTGGAT GTGTTTTTTG TTTCCACTTT GGTGGCGTAT


 


301
ATCAAGCTCT CGTCTGTGGC AGAGGTTCGC TTCGGGCCGG CGTTTTATCT


 


351
GATGTTCGCG CTGTCAGTTA TGCTGATTCG GACTTCGGTA TCGGTTCCCC


 


401
AGCATTGGGT GTATTTTCAA ATCGGGCGGC TGACGGGGGA TAATGCGGTT


 


451
CAGACGGCAT CGGAAGGTAA AACCTGTTGC AGCCGCTGCC TGTATTTCCG


 


501
CGACAGTGCC GAATCCCCCT GCGGCGTGTG CGGTGCGGAA CTGTACCGCC


 


551
GACGGCCGAA AAGTCTGAGT ATTTCGTCGG CGTTTCTGAC GGCGGCGGTT


 


601
ATTTTGTATT TCCCTGCCAA TATCCTGCCG ATTATGATTT CGTCCAATCC


 


651
TGCCGCCACG GAGGTCAATA CCATCCTTAA CGGCATCGCT TATATGTGGG


 


701
ACGAGGGCGA CAGGCTGATT GCGGCGGTTA TTTTCAGCGC GAGTATTTTG


 


751
GTGCCGGTAC TGAAGATTGC GGCAATGTCG GTTTTGATTG CGTCCGCCCG


 


801
CTTCGCTTTG CCAACGGGTG CAAAGAAATT GTCGCACCTC TACCGCATCA


 


851
CCGAAGCGGT CGGCCGCTGG TCGATGATTG ATATTTTTGT GATTATTATT


 


901
TTGATGTGTT CGTTCCACAC TTATGCCGCG CGCGTCATTC CGGGCAGTGC


 


951
GGCAGTCTAT TTCTGCCTGG TCGTGATTCT GACGATGCTG TCCGCCTATT


 


1001
ATTTCGACCC GCGCCTGCTT TGGGACAAAC GCGCTTCAGA CGGCATTGCT


 


1051
TTCAATGAAA CGGAAAAACA TGACTGA






This corresponds to the amino acid sequence <SEQ ID 628; ORF 153>:










m153.pep




1
MAFAYGMTYI EVGIPGAASV LSLPEMMRLM VFQDYGFLAE VMFVLTFGAP


 


51
VLFLLLCLYV YAALIRKQAY PALRLATRVM VRLRQAMMVD VFFVSTLVAY


 


101
IKLSSVAEVR FGPAFYLMFA LSVMLIRTSV SVPQHWVYFQ IGRLTGDNAV


 


151
QTASEGKTCC SRCLYFRDSA ESPCGVCGAE LYRRRPKSLS ISSAFLTAAV


 


201
ILYFPANILP IMISSNPAAT EVNTILNGIA YMWDEGDRLI AAVIFSASIL


 


251
VPVLKIAAMS VLIASARFAL PTGAKKLSHL YRITEAVGRW SMIDIFVIII


 


301
LMCSFHTYAA RVIPGSAAVY FCLVVILTML SAYYFDPRLL WDKRASDGIA


 


351
FNETEKHD*






m153/g153 96.1% identity in 358 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 629>:










a153.seq




1
ATGGCGTTTG CTTACGGTAT GACGTATATC GAGGTCGGGA TACCGGGTGC


 


51
GGCATCCGTC CTTTCGCTGC CCGAGATGAT GCGCCTGATG GTGTTTCAGG


 


101
ATTATGGTTT TTTGGCCGAA GTGATGTTTG TGCTGACCTT CGGCGCGCCG


 


151
GTTCTGTTTC TGCTGCTGTG CCTGTATGTC TATGCCGCGC TGATACGGAA


 


201
ACAGGCGTAT CCTGCGCTGC GTTTGGCAAC GCGTGTGATG GTGCGCTTGA


 


251
GACAGGCGAT GATGGTGGAT GTGTTTTTTG TTTCCACTTT GGTGGCGTAT


 


301
ATCAAGCTCT CGTCTGTGGC AGAGGTTCGC TTCGGATCGG CGTTTTATCT


 


351
GATGTTCGCG CTGTCGGTTA TGCTGATTCG GACTTCGGTA TCGGTTCCCC


 


401
AGCATTGGGT GTATTTTCAA ATCGGGCGGC TGACGGGGGA TAATGCGGTT


 


451
CAGACGGCAT CGGAAGGTAA AACCTGTTGC AGCCGCTGCC TGTATTTCCG


 


501
CGACAGTGCC GAATCCCCCT GCGGCGTGTG CGGTGCGGAA CTGTACCGCC


 


551
GACGGCCGAA AAGTCTGAGT ATTTCGTCGG CGTTTCTGAC GGCGGCGGTT


 


601
ATTTTGTATT TCCCTGCCAA TATCCTGCCG ATTATGATTT CGTCCAATCC


 


651
TGCCGCCACG GAGGTCAATA CCATCCTTAA CGGCATCGCT TATATGTGGG


 


701
ACGAGGGCGA CAGGCTGATT GCGGCGGTTA TTTTCAGCGC GAGTATTTTG


 


751
GTGCCGGTAC TGAAGATTGC GGCAATGTCG GTTTTGATTG CGTCCGCCCG


 


801
CTTCGCTTTG CCAACGGGTG CAAAGAAATT GTCGCACCTC TACCGCATCA


 


851
CCGAAGCGGT CGGCCGCTGG TCGATGATTG ATATTTTTGT GATTATTATT


 


901
TTGATGTGTT CGTTCCACAC TTATGCCGCG CGCGTCATTC CGGGCAGTGC


 


951
GGCAGTCTAT TTCTGCCTGG TCGTGATTCT GACGATGCTG TCCGCCTATT


 


1001
ATTTCGACCC GCGCCTGCTT TGGGACAAAC GCGCTTCAGA CGGCATTGCT


 


1051
TTCAATGAAA CGGAAAAACA TGACTGA






This corresponds to the amino acid sequence <SEQ ID 630; ORF 153.a>:










a153.pep




1
MAFAYGMTYI EVGIPGAASV LSLPEMMRLM VFQDYGFLAE VMFVLTFGAP


 


51
VLFLLLCLYV YAALIRKQAY PALRLATRVM VRLRQAMMVD VFFVSTLVAY


 


101
IKLSSVAEVR FGSAFYLMFA LSVMLIRTSV SVPQHWVYFQ IGRLTGDNAV


 


151
QTASEGKTCC SRCLYFRDSA ESPCGVCGAE LYRRRPKSLS ISSAFLTAAV


 


201
ILYFPANILP IMISSNPAAT EVNTILNGIA YMWDEGDRLI AAVIFSASIL


 


251
VPVLKIAAMS VLIASARFAL PTGAKKLSHL YRITEAVGRW SMIDIFVIII


 


301
LMCSFHTYAA RVIPGSAAVY FCLVVILTML SAYYFDPRLL WDKRASDGIA


 


351
FNETEKHD*






m153/a153 99.7% identity in 358 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 631>:










g154.seq




1
ATGACTGACA ACAGCCCTCC TCCAAACGGA CACGCTCAAG CACGCGTCCG


 


51
CAAAAACAAC accttcctCT CCGCCGTCTG GCTGGTCCCG CTGATCGCGC


 


101
TGATTGCCGG CGGCTGGCTT TGGGTTAAGG AAATCCGCAA CAGGGGGCCT


 


151
GTGGTTACGC TCTTGATGGA CAGCGCGGAA GGCATCGAAG TCAACAATAC


 


201
GGTCATTAAG GTATTGAGCA TCGATGTCGG ACGCGTTACC CGAATCAAAC


 


251
TGCGCGACGA CCAAAAAGGC GTGGAAGTTA CTGCCCAACT CAATGCGGAC


 


301
GTATCCGGCC TCATCCGCAG CGATACCCAG TTTTGGGTGG TCAAGCCGCG


 


351
TATCGACCAA AGCGGcgtAA CCGGTTTGGG TACGCTGCTT TCGGGTTCGT


 


401
ACATCGCTTT TACACCCGGC AAAAGCGGCG AGGCAAAAGA CGTGTTCCAA


 


451
GTGCAGGACA TTCCGCCCGT TACCGCCATC GGGCAAAgcg GGCTGCGCTT


 


501
GAATTTGATT GGTAAAAACG AccgCATCCT CAACGTcaaC AGCCCTGTTT


 


551
TGTATGAAAA CTTTATGGTC GGGCAAATCG AAAGCGCGCA TTTCGAcccG


 


601
TCCGACCAAA GCGTGCATTA CACCATCTTC ATCCAAAGCC CCAACGACAA


 


651
ACTGATTCAT TCCGCCAGCC GTTTTTGGCT GGAAAGCGGC ATCAATATCG


 


701
AAACCACAGG CAGCGGCATC AAACTCAATT CCGCCCCTCT GCCTGCCCTG


 


751
CTGTCAGGCG CGATTTCATT TGATTCGCCG AAAACCAAAA ACAGTAAAAA


 


801
CGTCAAAAGC GAGGACAGCT TCACGCTTTA CGACAGCCGC AGCGAAATCG


 


851
CCAACCTGCC TGACGACCGC TCGCTGTACT ACACCGCGTT TTTCAAACAA


 


901
TCCGTGCGCG GACTGACCGT cggTTCGCCT GTcgaATACA AAGGGCtgaA


 


951
TGTcggCATG GTTTCCGATG TCCCTTATTT TGACCGCAAt gacagCCTGC


 


1001
ACCtgtTTGA aaacggctgg aTTcccGtac gCATCCGCAT cgagccTTCC


 


1051
CGTTTGGAAA TCAATGCCGA CGAGCAAAGC AAAGAGCATT GGAAACAACA


 


1101
ATTCCAGACG GCCTTAAACA AAGGCCTGAC CGCCACCATC TCCAGCAACA


 


1151
ACCTGCTGAC CGGCGGCAAA ATGATTGAGT TGAACGATCA GCCTTCCGCC


 


1201
TCGCCCAAGC TGCGACCGCA TACCGTTTAT GCAGGCGATA CCGTCATCGC


 


1251
CACACGGGGC GGCGGTTTGG ATGACTTGCA GGTCAAATTG GCGGATTTGC


 


1301
TGGACaaatT CAACAATCTG CCATTggata aAACCGTTGC CGAATTGAAC


 


1351
GGCTCGCTCG CCGAACTCAA GTCCGCACTC AAATCCGCCA ATGCCGCCCT


 


1401
AAGCTCCATT GacaAACTGG TCGgcaaTCC GCAGACGCAA AACATCCCGA


 


1451
ACGAACTGAA CCAAACTCTG AAAGAGTTGC GCATAACCCT GCAAGGCGTA


 


1501
TCGcctCAAT CGCCTATCTa cgGAgacgta caAAATAcgc tgCaAAGTTT


 


1551
GGACAAAACC TTAAAagacg TtcaACCCGT CATTAACACT TTGAaAGAAa


 


1601
aacCCaaCgc actGATTTtc aacaACAGCA GCAAAGAccc tATCCCGAAA


 


1651
GGAAGCCGAT AA






This corresponds to the amino acid sequence <SEQ ID 632; ORF 154.ng>:










g154.pep




1
MTDNSPPPNG HAQARVRKNN TFLSAVWLVP LIALIAGGWL WVKEIRNRGP


 


51
VVTLLMDSAE GIEVNNTVIK VLSIDVGRVT RIKLRDDQKG VEVTAQLNAD


 


101
VSGLIRSDTQ FWVVKPRIDQ SGVTGLGTLL SGSYIAFTPG KSGEAKDVFQ


 


151
VQDIPPVTAI GQSGLRLNLI GKNDRILNVN SPVLYENFMV GQIESAHFDP


 


201
SDQSVHYTIF IQSPNDKLIH SASRFWLESG INIETTGSGI KLNSAPLPAL


 


251
LSGAISFDSP KTKNSKNVKS EDSFTLYDSR SEIANLPDDR SLYYTAFFKQ


 


301
SVRGLTVGSP VEYKGLNVGM VSDVPYFDRN DSLHLFENGW IPVRIRIEPS


 


351
RLEINADEQS KEHWKQQFQT ALNKGLTATI SSNNLLTGGK MIELNDQPSA


 


401
SPKLRPHTVY AGDTVIATRG GGLDDLQVKL ADLLDKFNNL PLDKTVAELN


 


451
GSLAELKSAL KSANAALSSI DKLVGNPQTQ NIPNELNQTL KELRITLQGV


 


501
SPQSPIYGDV QNTLQSLDKT LKDVQPVINT LKEKPNALIF NNSSKDPIPK


 


551
GSR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 633>:










m154.seq




1
ATGACTGACA ACAGCCCTCC TCCAAACGGA CACGCCCAAG CACGCGTCCG


 


51
CAAAAACAAC ACCTTCCTCT CTGCCGTCTG GCTGGTTCCG CTGATCGCGC


 


101
TGATTGCCGG CGGCTGGCTT TGGGTTAAGG AAATCCGCAA CAGGGGGCCT


 


151
GTGGTTACGC TCTTGATGGA CAGCGCGGAA GGCATTGAGG TCAACAATAC


 


201
GGTCATCAAA GTATTGAGCA TCGATGTCGG ACGCGTTACC CGAATCAAAC


 


251
TGCGCGACGA CCAAAAAGGC GTGGAAGTAA CCGCCCAACT CAATGCGGAC


 


301
GTATCCGGCC TCATCCGCAG CGATACCCAG TTTTGGGTGG TCAAGCCGCG


 


351
TATCGACCAA AGCGGCGTAA CCGGTTTGGG TACGCTGCTT TCGGGTTCGT


 


401
ACATCGCCTT TACACCCGGC AAAAGCGACG AGGCAAAAGA CGTGTTCCAA


 


451
GTGCAGGACA TTCCGCCCGT TACCGCCATC GGGCAAAGCG GGCTGCGCTT


 


501
GAATTTGATT GGTAAAAACG ACCGCATCCT CAACGTCAAC AGCCCTGTTT


 


551
TGTATGAAAA TTTTATGGTC GGGCAAGTCG AAAGCGCGCA TTTCGACCCG


 


601
TCCGACCAAA GCGTGCATTA CACCATCTTC ATCCAAAGCC CCAACGACAA


 


651
ACTGATTCAT TCCGCCAGCC GTTTTTGGCT GGAAAGCGGC ATCAATATCG


 


701
AAACCACAGG CAGCGGCATC AAACTCAATT CCGCCCCTCT GCCTGCCCTG


 


751
CTGTCGGGCG CGATTTCATT TGATTCGCCG AAAACCAAAA ACAGTAAAAA


 


801
CGTCAAAAGC GAAGACAGCT TCACGCTTTA CGACAGCCGC AGCGAAGTCG


 


851
CCAACCTGCC TGACGACCGC TCGCTGTACT ACACCGCGTT TTTCAAACAA


 


901
TCCGTGCGCG GCCTGACCGT CGGTTCGCCC GTCGAGTACA AAGGGCTGAA


 


951
TGTCGGCGTG GTTTCCGACG TTCCTTATTT CGACCGCAAC GACAGCCTGC


 


1001
ACCTGTTTGA AAACGGCTGG ATACCCGTAC GCATCCGCAT TGAACCTTCC


 


1051
CGTTTGGAAA TCAATGCCGA CGAACAAAGC AAAGAACATT GGAAACAACA


 


1101
ATTTCAGACG GCCTTAAACA AAGGCCTGAC CGCCACCATC TCCAGCAACA


 


1151
ACCTGCTGAC CGGAAGCAAA ATGATTGAGT TGAACGATCA GCCTTCCGCA


 


1201
TCACCTAAGC TGCGACCGCA TACCGTTTAT GCAGGCGATA CCGTTATCGC


 


1251
GACCCAGGGC GGCGGTTTGG ACGATTTGCA GGTCAAATTG GCGGATTTGC


 


1301
TGGACAAGTT CGACAAACTG CCTTTAGATA AGACGGTTGC CGAATTGAAC


 


1351
GGTTCGCTTG CCGAGCTCAA ATCCACACTC AAATCTGCCA ATGCCGCCCT


 


1401
AAGCTCCATC GACAAACTGG TCGGCAAACC GCAGACACAA AACATTCCGA


 


1451
ACGAACTGAA CCAAACCCTG AAAGAGTTGC GCACAACCCT GCAAGGCGTA


 


1501
TCGCCGCAAT CGCCTATCTA CGGCGACGTA CAAAATACGC TGCAAAGTTT


 


1551
GGACAAAACT TTAAAAGACG TTCAACCCGT GATTAATACT TTGAAAGAAA


 


1601
AACCCAACGC GCTGATTTTC AACAGCAGCA GCAAAGACCC TATCCCGAAA


 


1651
GGAAGCCGAT AA






This corresponds to the amino acid sequence <SEQ ID 634 ORF 154.a>:










m154.pep




1
MTDNSPPPNG HAQARVRKNN TFLSAVWLVP LIALIAGGWL WVKEIRNRGP


 


51
VVTLLMDSAE GIEVNNTVIK VLSIDVGRVT RIKLRDDQKG VEVTAQLNAD


 


101
VSGLIRSDTQ FWVVKPRIDQ SGVTGLGTLL SGSYIAFTPG KSDEAKDVFQ


 


151
VQDIPPVTAI GQSGLRLNLI GKNDRILNVN SPVLYENFMV GQVESAHFDP


 


201
SDQSVHYTIF IQSPNDKLIH SASRFWLESG INIETTGSGI KLNSAPLPAL


 


251
LSGAISFDSP KTKNSKNVKS EDSFTLYDSR SEVANLPDDR SLYYTAFFKQ


 


301
SVRGLTVGSP VEYKGLNVGV VSDVPYFDRN DSLHLFENGW IPVRIRIEPS


 


351
RLEINADEQS KEHWKQQFQT ALNKGLTATI SSNNLLTGSK MIELNDQPSA


 


401
SPKLRPHTVY AGDTVIATQG GGLDDLQVKL ADLLDKFDKL PLDKTVAELN


 


451
GSLAELKSTL KSANAALSSI DKLVGKPQTQ NIPNELNQTL KELRTTLQGV


 


501
SPQSPIYGDV QNTLQSLDKT LKDVQPVINT LKEKPNALIF NSSSKDPIPK


 


551
GSR*






m154/g154 97.8% identity in 553 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 635>:










a154.seq




1
ATGACTGACA ACAGCCCTCC TCCAAACGGA CACGCCCAAG CACGCGTCCG


 


51
CAAAAACAAC ACCTTCCTCT CTGCCGTCTG GCTGGTTCCG CTGATCGCGC


 


101
TGATTGCCGG CGGCTGGCTT TGGGTTAAGG AAATCCGCAA CAGGGGGCCT


 


151
GTGGTTACGC TCTTGATGGA CAGCGCGGAA GGCATTGAGG TCAACAATAC


 


201
GGTCATCAAA GTATTGAGCA TCGATGTCGG ACGCGTTACC CGAATCAAAC


 


251
TGCGCGACGA CCAAAAAGGC GTGGAAGTAA CCGCCCAACT CAATGCGGAC


 


301
GTATCCGGCC TCATCCGCAG CGATACCCAG TTTTGGGTGG TCAAGCCGCG


 


351
TATCGACCAA AGCGGCGTAA CCGGTTTGGG TACGCTGCTT TCGGGTTCGT


 


401
ACATCGCCTT TACACCCGGC AAAAGCGACG AGGCAAAAGA CGTGTTCCAA


 


451
GTGCAGGACA TTCCGCCCGT TACCGCCATC GGGCAAAGCG GGCTGCGCTT


 


501
GAATTTGATT GGTAAAAACG ACCGCATCCT CAACGTCAAC AGCCCTGTTT


 


551
TGTATGAAAA CTTTATGGTC GGGCAAGTCG AAAGCGCGCA TTTCGACCCG


 


601
TCCGACCAAA GCGTGCATTA CACCATCTTC ATCCAAAGCC CCAACGACAA


 


651
ACTGATTCAT TCCGCCAGCC GTTTCTGGCT GGAAAGCGGC ATCAATATCG


 


701
AAACCACAGG CAGCGGCATC AAACTCAATT CCGCCCCTCT GCCTGCCCTG


 


751
CTGTCGGGCG CGATTTCATT TGATTCGCCG AAAACCAAAA ACAGTAAAAA


 


801
CGTCAAAAGC GAAGACAGCT TCACGCTTTA CGACAGCCGC AGCGAAGTCG


 


851
CCAACCTGCC TGATGACCGT TCGCTGTACT ACACCGCGTT TTTCAAACAA


 


901
TCCGTGCGCG GACTGACCGT CGGTTCGCCT GTCGAGTACA AAGGGCTGAA


 


951
TGTCGGCGTG GTTTCCGATG TTCCTTATTT CGACCGCAAC GACAGCCTGC


 


1001
ACCTGTTTGA AAACGGCTGG ATTCCCGTAC GCATCCGTAT TGAGCCTTCC


 


1051
CGTTTGGAAA TCAATGCCGA CGAACAAAGC AAAGAACATT GGAAACAACA


 


1101
ATTTCAGACG GCCTTAAACA AAGGCCTGAC CGCCACCATC TCCAGCAACA


 


1151
ACCTGCTGAC CGGCAGCAAA ATGATTGAGT TGAACGATCA GCCTTCCGCC


 


1201
TCGCCCAAGC TGCGACCGCA TACCGTTTAT GCAGGCGATA CCGTTATCGC


 


1251
GACCCAGGGC GGCGGTTTGG ACGATTTGCA GGTCAAATTG GCGGATTTGC


 


1301
TGGACAAGTT CGACAAACTG CCTTTAGATA AGACGGTTGC CGAATTGAAC


 


1351
GGTTCGCTTG CCGAGCTCAA ATCCACACTC AAATCTGCCA ATGCCGCCCT


 


1401
AAGCTCCATC GACAAACTGG TCGGCAAACC GCAGACACAA AACATTCCGA


 


1451
ACGAACTGAA CCAAACCCTG AAAGAGTTGC GCACAACCCT GCAAGGCGTA


 


1501
TCGCCTCAAT CGCCTATCTA CGGCGACGTA CAAAATACGC TGCAAAGTTT


 


1551
GGACAAAACC TTAAAAGACG TTCAACCCGT CATTAACACT TTGAAAGAAA


 


1601
AACCCAACGC GCTGATTTTC AACAGCAGCA GCAAAGACCC TATCCCGAAA


 


1651
GGAAGCCGAT AA






This corresponds to the amino acid sequence <SEQ ID 636; ORF 154.a>:










a154.pep




1
MTDNSPPPNG HAQARVRKNN TFLSAVWLVP LIALIAGGWL WVKEIRNRGP


 


51
VVTLLMDSAE GIEVNNTVIK VLSIDVGRVT RIKLRDDQKG VEVTAQLNAD


 


101
VSGLIRSDTQ FWVVKPRIDQ SGVTGLGTLL SGSYIAFTPG KSDEAKDVFQ


 


151
VQDIPPVTAI GQSGLRLNLI GKNDRILNVN SPVLYENFMV GQVESAHFDP


 


201
SDQSVHYTIF IQSPNDKLIH SASRFWLESG INIETTGSGI KLNSAPLPAL


 


251
LSGAISFDSP KTKNSKNVKS EDSFTLYDSR SEVANLPDDR SLYYTAFFKQ


 


301
SVRGLTVGSP VEYKGLNVGV VSDVPYFDRN DSLHLFENGW IPVRIRIEPS


 


351
RLEINADEQS KEHWKQQFQT ALNKGLTATI SSNNLLTGSK MIELNDQPSA


 


401
SPKLRPHTVY AGDTVIATQG GGLDDLQVKL ADLLDKFDKL PLDKTVAELN


 


451
GSLAELKSTL KSANAALSSI DKLVGKPQTQ NIPNELNQTL KELRTTLQGV


 


501
SPQSPIYGDV QNTLQSLDKT LKDVQPVINT LKEKPNALIF NSSSKDPIPK


 


551
GSR*






m154/a154 100.0% identity in 553 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 637>:










g155.seq




1
atGAAaatcg GtatcCCACG CGAGTCAtta tcCGGCGAAA cccgcgtagc


 


51
ctgcAcgccc gCCACCGTTG CCctgctggg caAactAGGC TTTGAAACCG


 


101
TTGtcgaAAG CGGTGCAggt TTGGCGGCAA GTTTggaCGA TGCCGCTTAC


 


151
CAAACAGCAG GCGCAACCGT TGCCGACAAA GCGGCGGTTT GGGCCTGCCC


 


201
TTTAATTTAT AAGGTCAACG CGCCGTCCGA AGGCGAGCTG CCGCTGCTCA


 


251
AAGAAGGTCA AACCATCGTC AGCTTCCTGT GGCCGCGCCA AAACGAGGCT


 


301
TTGGTCGAGG CCTTGCGCGC CAAGAAAGTC AACGCGCTGG CGATGGACAT


 


351
GGTTCCCCGC ATTTCCCGCG CTCAGGCCTT GGACGCTTTG TCTTCAATGG


 


401
CAAACATCAG CGGCTACCGC GCCGTGATTG AAGCCGCCAA CGCCTTCGGC


 


451
CGTTTCTTCA CCGGTCAAAT CACTGCCGCC GGCAAAGTGC CGCCTGCGCA


 


501
GGTTTTGGTG ATTGGCGCCG GTGTGGCGGG TTTGGCGGCA ATCGGTACGG


 


551
CAAATTCGCT CGGCGCAGTG GTGCGCGCGT TCGATACCCG CTTGGAAGTG


 


601
GCGGAACAAA TCGAATCGAT GGGCGGTAAG TTcctGAAAC TCGACTTCCT


 


651
GCAAGAATCG GGCGGCAGCG GAGACGgctA CGCCAAAGTG ATGAGCGACG


 


701
AATTTATCGC CGCCGAAATG AAGCTCTTTG CCGAACAGGC GAAAGAAGTG


 


751
GACATCATCA TCACCACCGC CGCCATTCCG GGCAAACCCG CTCCCAAGCT


 


801
GATTACCAAA GAAATGGTGG AAAGCATGAA ATCCGGATCC GTCATCGTCG


 


851
ATTTGGCGGC GACGGGCGGC AACTGCGAAC TCACCCGACC GGGCGAATTG


 


901
TCCGTAACCG GCAACGGCGT GAAAATCATC GGCTACACCG ACATGGCAAA


 


951
CCGCCTTGCC GGACAGTCTT CCCAGCTTTA CGCCACCAAC TTGGTGAACC


 


1001
TGACCAAGCT GTTAAGCCCG AACAAAGAcg gcgaAATCAC GCTGGACTTC


 


1051
GAAGacgtGA TTATCCGCAA TATGACCGTT ACCCGcgacg gcgaaATCAC


 


1101
CTTCCCGCCT CCGccgaTTc aggtTTCcgc ccggccgCAG CAAAcgccgt


 


1151
ctgaAAAagc cgcGCCTGCC GCCAagcccg AgccGaaacc tgttCCcctg


 


1201
tggaAAAaac tcgCGCCCGC CGCcatcgCC GCCGTATTGG tgctgtgGgt


 


1251
cggCgcggtc gcacccgcag CATTCTTGAA CCACTTTATC GTCTTCGTCC


 


1301
TCGCCTGCGT CATCGGCTAC CATGTCGTTT GgaacgTCAG CCACTCGCTG


 


1351
CACACACCGC TGAtgtcggt aaccaaCgcc atctccGGCA tcatggtcgt


 


1401
cggCGCGCTG CTGCAAATCG GTCAGGGcaa cggcttcgtT TCgctGCTGT


 


1451
CGTTTGTTGC CATCCTGATT GCCGGCATCA ATATCTTCGG CGGCTTTGCG


 


1501
GTTACACGGC GTATGCTGAA TATGTTTAAG AAAGGGTAA






This corresponds to the amino acid sequence <SEQ ID 638; ORF 155.ng>:










g155.pep




1
MKIGIPRESL SGETRVACTP ATVALLGKLG FETVVESGAG LAASLDDAAY


 


51
QTAGATVADK AAVWACPLIY KVNAPSEGEL PLLKEGQTIV SFLWPRQNEA


 


101
LVEALRAKKV NALAMDMVPR ISRAQALDAL SSMANISGYR AVIEAANAFG


 


151
RFFTGQITAA GKVPPAQVLV IGAGVAGLAA IGTANSLGAV VRAFDTRLEV


 


201
AEQIESMGGK FLKLDFLQES GGSGDGYAKV MSDEFIAAEM KLFAEQAKEV


 


251
DIIITTAAIP GKPAPKLITK EMVESMKSGS VIVDLAATGG NCELTRPGEL


 


301
SVTGNGVKII GYTDMANRLA GQSSQLYATN LVNLTKLLSP NKDGEITLDF


 


351
EDVIIRNMTV TRDGEITFPP PPIQVSARPQ QTPSEKAAPA AKPEPKPVPL


 


401
WKKLAPAAIA AVLVLWVGAV APAAFLNHFI VFVLACVIGY HVVWNVSHSL


 


451
HTPLMSVTNA ISGIMVVGAL LQIGQGNGFV SLLSFVAILI AGINIFGGFA


 


501
VTRRMLNMFK KG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 639>:










m155.seq




1
ATGAAAATCG GTATCCCACG CGAGTCATTA TCCGGCGAAA CCCGCGTCGC


 


51
CTGTACGCCC GCCACCGTCG CCCTGCTGGG CAAACTGGGC TTTGAAACCG


 


101
TTGTCGAAAG CGGTGCAGGT TTGGCGGCAA GTTTGGACGA TGCCGCTTAC


 


151
CAAACAGCAG GCGCAACCGT TGCCGACAAA GCGGCGGTTT GGGTCTGCCC


 


201
TTTGATTTAT AAGGTCAACG CGCCGTCCGA ACAGGAACTG CCGCTTTTGA


 


251
ACGAAGGTCA AACCATCGTC AGCTTCCTGT GGCCGCGCCA AAACGAGGCT


 


301
TTGGTCGAAG CCTTGCGCGC CAAGAAAGTG AACGCGCTGG CGATGGATAT


 


351
GGTGCCCCGC ATTTCGCGCG CGCAGGCTTT GGACGCTTTG TCTTCGATGG


 


401
CAAACATCAG CGGCTACCGC GCCGTAATTG AAGCCGCCAA CGCCTTCGGC


 


451
CGTTTCTTCA CCGGTCAAAT TACCGCCGCC GGCAAAGTGC CGCCCGCGCA


 


501
GGTTTTGGTG ATTGGTGCAG GTGTGGCAGG TTTGGCGGCG ATCGGTACGG


 


551
CAAACTCGCT CGGCGCAGTG GTACGCGCGT TCGATACCCG CTTGGAAGTG


 


601
GCGGAACAAA TCGAATCGAT GGGCGGCAAG TTCCTGAAAC TCGACTTCCC


 


651
ACAAGAATCG GGCGGCAGCG GAGACGGCTA CGCCAAAGTG ATGAGCGACG


 


701
AATTTATCGC AGCCGAGATG AAGCTCTTTG CCGAGCAGGC GAAAGAAGTG


 


751
GACATCATCA TCACCACCGC CGCCATTCCG GGCAAACCCG CGCCCAAGCT


 


801
GATTACCAAA GAAATGGTGG AAAGCATGAA ATCCGGCTCC GTCATCGTCG


 


851
ATTTGGCGGC GGCGACGGGC GGCAACTGCG AACTCACCCG CCCGGGCGAA


 


901
TTGTCCGTAA CCGGCAACGG CGTGAAAATC ATCGGCTACA CCGACATGGC


 


951
AAACCGCCTT GCCGGACAGT CTTCCCAGCT TTACGCCACC AACTTGGTCA


 


1001
ACCTGACCAA GCTGTTAAGC CCGAACAAAG ACGGCGAAAT CACGTTGGAC


 


1051
TTCGAAGACG TGATTATCCG CAACATGACC GTTACCCACG ACGGCGAAAT


 


1101
CACCTTCCCG CCTCCGCCGA TTCAAGTTTC CGCCCAGCCG CAGCAAACGC


 


1151
CGTCTGAAAA AGCCGTGCCT GCCGCCAAGC CCGAGCCAAA ACCCGTTCCC


 


1201
CTGTGGAAAA AACTCGCGCC CGCCGTCATC GCCGCCGTCT TGGTACTGTG


 


1251
GGTCGGCGCG GTCGCACCCG CAGCATTCCT GAACCACTTT ATCGTGTTCG


 


1301
TTCTCGCCTG CGTCATCGGC TACTACGTCG TCTGGAACGT CAGCCACTCG


 


1351
CTGCACACAC CGCTGATGTC GGTAACCAAC GCCATCTCCG GCATCATCGT


 


1401
CGTCGGCGCG CTGCTGCAAA TCGGTCAGGG CAACGGCTTC GTTTCGCTGC


 


1451
TGTCGTTTGT TGCCATCCTG ATTGCCGGCA TCAACATCTT CGGCGGCTTT


 


1501
GCGGTAACAC GGCGTATGCT GAATATGTTT AAGAAAGGGT AA






This corresponds to the amino acid sequence <SEQ ID 640; ORF 155>:










m155.pep




1
MKIGIPRESL SGETRVACTP ATVALLGKLG FETVVESGAG LAASLDDAAY


 


51
QTAGATVADK AAVWVCPLIY KVNAPSEQEL PLLNEGQTIV SFLWPRQNEA


 


101
LVEALRAKKV NALAMDMVPR ISRAQALDAL SSMANISGYR AVIEAANAFG


 


151
RFFTGQITAA GKVPPAQVLV IGAGVAGLAA IGTANSLGAV VRAFDTRLEV


 


201
AEQIESMGGK FLKLDFPQES GGSGDGYAKV MSDEFIAAEM KLFAEQAKEV


 


251
DIIITTAAIP GKPAPKLITK EMVESMKSGS VIVDLAAATG GNCELTRPGE


 


301
LSVTGNGVKI IGYTDMANRL AGQSSQLYAT NLVNLTKLLS PNKDGEITLD


 


351
FEDVIIRNMT VTHDGEITFP PPPIQVSAQP QQTPSEKAVP AAKPEPKPVP


 


401
LWKKLAPAVI AAVLVLWVGA VAPAAFLNHF IVFVLACVIG YYVVWNVSHS


 


451
LHTPLMSVTN AISGIIVVGA LLQIGQGNGF VSLLSFVAIL IAGINIFGGF


 


501
AVTRRMLNMF KKG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 155 shows 97.9% identity over a 513 aa overlap with a predicted ORF (ORF 155.ng) from N. gonorrhoeae: 
m155/g155 97.9% identity in 513 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 641>:










a155.seq




1
ATGAAAATCG GTATCCCACG TGAGTCATTA TCCGGCGAAA CCCGCGTCGC


 


51
CTGTACGCCC GCCACCGTCG CCCTGCTGGG CAAACTGGGC TTTGAAACCG


 


101
TTGTCGAAAG CGGCGCAGGT TTGGCGGCAA GTTTGGACGA TGCCGCTTAC


 


151
CAAGCAGCAG GCGCAACCGT TGCCGACAAA GCAGCGGTTT GGGCATACCC


 


201
TTTAATTTAT AAGGTTAACG CGCCGTCCGA AGACGAGCTG CCGCTGCTCA


 


251
AAGAAGGACA GACCATCGTC AGCTTCCTGT GGCCGCGCCA AAACGAGGCT


 


301
TTGGTCGAAG CCTTGCGCGC CAAGAAAGTG AACGCGCTGG CAATGGACAT


 


351
GGTGCCCCGC ATTTCGCGCG CGCAGGCTTT GGACGNTTTG TCTTNGATGG


 


401
CAAACATCAG CGGCTACCGC GCCGTGATTG AAGCCGCCAA CGCCTTCGGC


 


451
CGTTTNTTCA CCGGCCAAAT TACTGCCGCA GGCAAAGTGC CGCCCGCGCA


 


501
GGTTTTGGTG ATTGGTGCAG GTGTGGCAGG TTTGGCGGCG ATCGGTACGG


 


551
CAAACTCGCT CGGCGCAGTG GTACGCGTGT TCGATACCCG CCTG.AAGTG


 


601
GCGGAACAAT TAGAATCGAT GGGCGGCAAG TTCCTGAAAC TCGACTTCCC


 


651
GCAAGAATCG GGCGGCAGCG GCGACGGCTA CGCCAAAGTG ATGAGCGACG


 


701
AATTTATCGC CGCCGAGATG AAGCTTTTTG CCGAGCAGGC GAAAGAAGTG


 


751
GACATCATCA TCACCACCGC CGCCATTCCG GGCAAACCCG CGCCCAAGCN


 


801
NNTNANCAAA GAAATGGTCG AAAGCATGAA ACCCGGCTCC GTCATCGTCG


 


851
ATTTGGCGGC GGCGACGGGC GGCAACTGCG AACTCACCAA ACAGGGCGAA


 


901
TTGTTCGTAA CCGGCAACGG CGTGAAAATC ATCGGCTACA CCGACATGGC


 


951
AAACCGCCTT GCCGGACAGT CTTCGCAGCT TTACGCCACC AACTTGGTCA


 


1001
ACCTGACCAA GCTGTTAAGC CCGAACAAAG ACGGCGAAAT CACGCTGGAC


 


1051
TTCGAAGACG TGATTATCCG CAACATGACC GTTACCCGCG ACGGCGAAAT


 


1101
CACCTTCCCG CCTCCGCCGA TTCAAGTTTC CGCCCAACCG CAGCAAACGC


 


1151
CGTCTGAAAA AGCCGCGCCT GCCGCCAAGC CCGAACCGAA ACCCGTTCCC


 


1201
CTGTGGAAAA AACTCGCGCC CGCCNTNATC GCCGCCGTGT TGGTACTGTG


 


1251
GGTCGGCGCG GTCGCACCCG CAGCATTCCT GAACCACTTT ATCGTCTTCG


 


1301
TCCTCGCCTG CGTCATCGGC TACTATGTCG TTTGGAACGT CAGCCACTCG


 


1351
CTGCACACAC CGCTGATGTC GGTGACCAAC GCCATTTCCG GCATCATCGT


 


1401
CGTCGGCGCG CTGCTGCAAA TCGGTCAGGG CAACGGCTTC GTTTCGCTGC


 


1451
TGTCGTTTGT TGCCATCCTG ATTGCCAGCA TCAACATCTT CGGCGGCTTC


 


1501
TTTGTAACGC GGCGGATGCT GAATATGTTT AGGAAAGGGT AA






This corresponds to the amino acid sequence <SEQ ID 642; ORF 155.a>:










a155.pep




1
MKIGIPRESL SGETRVACTP ATVALLGKLG FETVVESGAG LAASLDDAAY


 


51
QAAGATVADK AAVWAYPLIY KVNAPSEDEL PLLKEGQTIV SFLWPRQNEA


 


101
LVEALRAKKV NALAMDMVPR ISRAQALDXL SXMANISGYR AVIEAANAFG


 


151
RXFTGQITAA GKVPPAQVLV IGAGVAGLAA IGTANSLGAV VRVFDTRLXV


 


201
AEQLESMGGK FLKLDFPQES GGSGDGYAKV MSDEFIAAEM KLFAEQAKEV


 


251
DIIITTAAIP GKPAPKXXXK EMVESMKPGS VIVDLAAATG GNCELTKQGE


 


301
LFVTGNGVKI IGYTDMANRL AGQSSQLYAT NLVNLTKLLS PNKDGEITLD


 


351
FEDVIIRNMT VTRDGEITFP PPPIQVSAQP QQTPSEKAAP AAKPEPKPVP


 


401
LWKKLAPAXI AAVLVLWVGA VAPAAFLNHF IVFVLACVIG YYVVWNVSHS


 


451
LHTPLMSVTN AISGIIVVGA LLQIGQGNGF VSLLSFVAIL IASINIFGGF


 


501
FVTRRMLNMF RKG*






m155/a155 95.3% identity in 513 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 643>:










g156.seq




1
ATGACTTTCG CCTATTGGTG CATTCTGATT GCCTGCCTAT TGCCGCTTTT


 


51
TTGTGCGGCG TATGCCAAAA AAGCGGGCGG ATTCCGGTTT AAAGACAACC


 


101
ACAATCCTCG CGGTTTTCTG GCACATACGC AAGGCGCAGC CGCCCGTGCC


 


151
CACGCCGCGC AGCAAAACGG TTTTGAAGCC TTTGCACCGT TTGCCGCCGC


 


201
CGTTTTGACG GCACACGCAA CCGGCAATGC CGGACAAGCA ACCGTCAACA


 


251
CGCTTGCCGG ATTGTTCATC CTGTTCCGCC TCGCCTTTAT CTGGTGCTAC


 


301
ATCGCAGACA AAGCAGCATT GCGCTCGCTG ATGTGGGCGG GCGGATTTGC


 


351
CTGCACCGTC GGACTGTTTG TCGCGGCTGC TTGA






This corresponds to the amino acid sequence <SEQ ID 644; ORF 156.ng>:










g156.pep




1
MTFAYWCILI ACLLPLFCAA YAKKAGGFRF KDNHNPRGFL AHTQGAAARA


 


51
HAAQQNGFEA FAPFAAAVLT AHATGNAGQA TVNTLAGLFI LFRLAFIWCY


 


101
IADKAALRSL MWAGGFACTV GLFVAAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 645>:










m156.seq




1
ATGACTTTCG CCTATTGGTG TATTCTGATT GCCTGCCTAT TGCCGCTTTT


 


51
TTGTGCGGCG TATGCCAAAA AAGCGGGCGG ATTCCGGTTT AAAGACAACC


 


101
ACAATCCGCG CGGTTTTCTA GCGCACACGC AAGGCGCAGC CGCCCGTGCC


 


151
CACGCCGCAC AGCAAAACGG TTTTGAAGCC TTTGCACCGT TTGCCGCCGC


 


201
CGTTTTGACG GCACACGCAA CCGGCAATGC GGCGCAATCG ACCATCAACA


 


251
CGCTTGCCTG CCTGTTCATC CTGTTCCGCC TCGCCTTTAT CTGGTGCTAT


 


301
ATCGCCGACA AAGCCGCTAT GCGCTCACTG ATGTGGGCAG GCGGATTTGC


 


351
CTGCACCGTC GGGCTGTTTG TCGCGGCTGC TTGA






This corresponds to the amino acid sequence <SEQ ID 646; ORF 156>:










m156.pep




1
MTFAYWCILI ACLLPLFCAA YAKKAGGFRF KDNHNPRGFL AHTQGAAARA


 


51
HAAQQNGFEA FAPFAAAVLT AHATGNAAQS TINTLACLFI LFRLAFIWCY


 


101
IADKAAMRSL MWAGGFACTV GLFVAAA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m156/g156 96.1% identity in 127 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 647>:










a156.seq




1
ATGACTTTCG CCTATTGGTG TATTCTGATT GCCTACCTAT TGCCGCTTTT


 


51
TTGTGCGGCG TATGCCAAAA AAGCGGGCGG ATTCCGGTTT AAAGACAACC


 


101
ACAATCCGCG CGATTTTCTG GCGCGCACGC AAGGCACAGC CGCCCGTGCC


 


151
CACGCCGCGC AGCAAAACGG TTTTGAAGCC TTTGCACCGT TTGCAGCCGC


 


201
CGTTTTGACG GCACACGCAA CCGGCAATGC CGGACAAGCA ACCGTCAACA


 


251
CGCTTGCCGG CCTGTTCATC CTGTTCCGCC TCGCCTTTAT CTGGTGCTAC


 


301
ATCGCAGACA AAGCAGCATT ACGCTCGCTG ATGTGGGTGG GCGGATTTGT


 


351
CTGCACCGTC GGGCTGTTTG TCGTGGCTGC TTGA






This corresponds to the amino acid sequence <SEQ ID 648; ORF 156.a>:










a156.pep




1
MTFAYWCILI AYLLPLFCAA YAKKAGGFRF KDNHNPRDFL ARTQGTAARA


 


51
HAAQQNGFEA FAPFAAAVLT AHATGNAGQA TVNTLAGLFI LFRLAFIWCY


 


101
IADKAALRSL MWVGGFVCTV GLFVVAA*






m156/a156 90.6% identity in 127 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 649>:










g157.seq




1
atgaggaacg aggAAAAACg cgccctgcgc cgcgaattgC gCgGgcggcg


 


51
ttcgcAAATg GGgcgagacg tGCGggCGGC GGCGgCgatA Aaaatcaacc


 


101
gcctgctcaa aCGTtatatc AAGCGCggtc gGaAaatcgG CGTGTATTgg


 


151
cCGATGGGCA AGGAATTGcg TTTGGGCGgc tTtgtcCGCG CGGCGCAAAA


 


201
ACGCgGCGCA AAactctatc tgccttATAT CGAACCGCAC ACGCGGCGGA


 


251
TGTGGTTTAC GCCGTATCCT GAACGCGGAA TGGAACGGGA ACGCAAGCGC


 


301
GGTAGGGCGA AGCTGCATGT CCCTCAGTTT GCAGGGCGCA AAATCCGCGT


 


351
GCACGGTTTG TCGGTATTGC TCGTCCCGCT TGTCGGCATA GACCGCGAAG


 


401
GCTACCGTTT GGGGCAGGCA GGCGGCTATT ACGATGCGAC GCTTTCGGCG


 


451
ATGAAATACC GTTTGCAGGC GAAAACCGTG GGCGTGGGCT TTGCCTGCCA


 


501
GTTGGTGGAC AGGCTCCCAC GCGAGGCGCA CGACCTGCCG CTGGACGGTT


 


551
TTGTATCGGA AGCGGGGATA TTGTGTTTTT AG






This corresponds to the amino acid sequence <SEQ ID 650; ORF 157.ng>:










g157.pep




1
MRNEEKRALR RELRGRRSQM GRDVRAAAAI KINRLLKRYI KRGRKIGVYW


 


51
PMGKELRLGG FVRAAQKRGA KLYLPYIEPH TRRMWFTPYP ERGMERERKR


 


101
GRAKLHVPQF AGRKIRVHGL SVLLVPLVGI DREGYRLGQA GGYYDATLSA


 


151
MKYRLQAKTV GVGFACQLVD RLPREAHDLP LDGFVSEAGI LCF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 651>:










m157.seq




1
ATGAGGAACG AGGAAAAACG CGCCCTGCGC CGCGAATTGC GCGGGCGGCG


 


51
TTCGCAAATG GGGCGGGACG TGCGGGCGGC GGCAACGGTA AAAATCAACC


 


101
ACCTGCTCAA ACGTTATATT AAAAAAGGGC GGAAAATCGG CGTGTATTGG


 


151
CCGATGGGCA AGGAATTGCG TTTGGACGGC TTTGTCCGCG CGGCGCAAAA


 


201
ACGCGGTGCG GAACTCTACC TGCCTTATAT CGAACCGCGT TCGCGGCGGA


 


251
TGTGGTTTAC GCCGTATCCT GCCGATGGAG TAAAACAAGA ACGCAAGCGC


 


301
GGTAGGGCGA AGCTGCATGT CCCTCAGTTT GCAGGTCGGA AAAAGCGTGT


 


351
GCATGATTTG AACCTCCTGC TTGTGCCAGT GGTCGGTATG GACAGGCTGG


 


401
GCTACCGCTT GGGACAGGCA GGCGGCTATT ACGATGCGAC GCTTTCAGCG


 


451
ATGAAATACC GTTTGCAGGC AAAAACCGTG GGCGTGGGCT TTGCCTGCCA


 


501
GTTGGTGGAC AGGCTGCCGG TCGAGGCGCA CGACCGGTCT TTGGACGGTT


 


551
TTGTGTCGGA GGCGGGGATA TTGTGTTTTT AG






This corresponds to the amino acid sequence <SEQ ID 652; ORF 157>:










m157.pep




1
MRNEEKRALR RELRGRRSQM GRDVRAAATV KINHLLKRYI KKGRKIGVYW


 


51
PMGKELRLDG FVRAAQKRGA ELYLPYIEPR SRRMWFTPYP ADGVKQERKR


 


101
GRAKLHVPQF AGRKKRVHDL NLLLVPVVGM DRLGYRLGQA GGYYDATLSA


 


151
MKYRLQAKTV GVGFACQLVD RLPVEAHDRS LDGFVSEAGI LCF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m157/g157 88.1% identity in 193 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 653>:










a157.seq




1
ATGAGGAACG AGGAAAAACA CGCCTTGCGC CGAGAGTTGC GCCGCGCCCG


 


51
CGCGCAGATG GGGCATCAAG GGCGGTTGGC GGCGGGGCAA ACGATTAACC


 


101
GCCTGCTCAA ACGTTATATC AAGCGTGGTC GGAAAATCGG CGTGTATTGG


 


151
CCGATGGGCA AGGAATTGCG TTTGGACGGC TTTGTCCGCG CGGCGCAAAA


 


201
ACGCGGTGCA AAACTTTATC TGCCTTATAT CGAACCGCGT TCGCGGCGGA


 


251
TGTGGTTTAC GCCGTATCCT GAAAGCGGAA TGGAACGGGA GCGCATACGG


 


301
GGCAGGGCGA AGTTGAACGT GCCGCAGTTT GCAGGGCGCA AAATCCGCGT


 


351
GCACGGTTTG TCGGTATTGC TCGTCCCGCT TGTCGGCATA GACCGCGAGG


 


401
GCTACCGCTT AGGACAGGCA GGCGGCTATT ACGATGCGAC GCTTGCGGCG


 


451
ATGAAATACC GTTTGCAGGC AAAAACCGTG GGCGTGGGCT TTGCCTGCCA


 


501
GTTTGTGGAC AGGCTGCCGC GCGAACCGCA CGATCTGCTG CTGGACGGTT


 


551
TTGTGTCGGA GGCGGGGATA TTGTGCTTTT AG






This corresponds to the amino acid sequence <SEQ ID 654; ORF 157.a>:










a157.pep




1
MRNEEKHALR RELRRARAQM GHQGRLAAGQ TINRLLKRYI KRGRKIGVYW


 


51
PMGKELRLDG FVRAAQKRGA KLYLPYIEPR SRRMWFTPYP ESGMERERIR


 


101
GRAKLNVPQF AGRKIRVHGL SVLLVPLVGI DREGYRLGQA GGYYDATLAA


 


151
MKYRLQAKTV GVGFACQFVD RLPREPHDLL LDGFVSEAGI LCF*






m157/a157 82.4% identity in 193 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 655>:










g158.seq




1
ATGAAAACCA ATTCAGAAGA ACTGACCGTA TTTGTTCAAG TGGTGGAAAG


 


51
CGGCAGCTTC AGCCGTGCGG CGgagcAGTT GGAGAtggCA AATTCTGCCG


 


101
TAAGCCGCAT CGTCAAACGG CTGGAGGAAA AGTTGGGCGT GAAcCTGCtc


 


151
aACCGCACCA CGCGGCAACT CAATCTGACG GAAGAAGGCG CGCAATATTT


 


201
CCGCCGCGCG CAGAGAATCC TGCAAGAAAT GGCAGCGGCG GAAACCGAAA


 


251
TGCTGGCAGT GCACGAAGTA CCGCAAGGCG TGTTGCGCGT GGATTCCGCG


 


301
ATGCcgatgg TGCTGCATCT GCTGGCGCCG CTGGCAGCAA AATTCAACGA


 


351
ACGCTATCCG CATATCcgaC TTTCGCTCGT TTCTTCCGAa ggctatatca


 


401
atctGattGA Acgcaaagtc gAtatTGCCT TACGGGCCGG AGAATTGGAC


 


451
GATTCCGGGC TGCGTGCACG CCATCTGTTT GACAGCCACT TCCGCGtagt


 


501
cgCCAGTCCT GAATATTTAG CAAAACACGG CACGCCACAA TCTGCAGAAG


 


551
atcTTGCCAA CCATCAATGT TTAGGCTTCA CAGAACCCGG TTCTCTAAAT


 


601
ACATGGGCGG TTTTAGAtgC GCAGGGAAAT CCCTATAAAA TTTCACCGCA


 


651
CTTTACCGCC AGCAGCGGTG AAATCTTACG CTCGTTGTGC CTTTCAAGtt


 


701
gCGGTATTGC TTGCTTATCA GATTTTTTGG TTGACAACGA CATCACTGAA


 


751
GGAAAGTTAA TTCCcctatt cgCCGAACAA ACCTCCAATA AAACACACCC


 


801
CTTTAATGCT GTTTATTACA GCGATAAAGC CGTCAACCTC CGCTTACGCG


 


851
TATTTTTGGA TTTTTTAGTG AAGGAACTGG GAAAAAATAT GAATAGAACG


 


901
AATACCAAAT AA






This corresponds to the amino acid sequence <SEQ ID 656; ORF 158.ng>:










g158.pep




1
MKTNSEELTV FVQVVESGSF SRAAEQLEMA NSAVSRIVKR LEEKLGVNLL


 


51
NRTTRQLNLT EEGAQYFRRA QRILQEMAAA ETEMLAVHEV PQGVLRVDSA


 


101
MPMVLHLLAP LAAKFNERYP HIRLSLVSSE GYINLIERKV DIALRAGELD


 


151
DSGLRARHLF DSHFRVVASP EYLAKHGTPQ SAEDLANHQC LGFTEPGSLN


 


201
TWAVLDAQGN PYKISPHFTA SSGEILRSLC LSSCGIACLS DFLVDNDITE


 


251
GKLIPLFAEQ TSNKTHPFNA VYYSDKAVNL RLRVFLDFLV KELGKNMNRT


 


301
NTK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 657>:










m158.seq




1
ATGAAAACCA ATTCAGAAGA ACTGACCGTA TTTGTTCAAG TGGTGGAAAG


 


51
CGGCAGCTTC AGCCGTGCGG CGGAGCAGTT GGCGATGGCA AATTCTGCCG


 


101
TAAGCCGCAT CGTCAAACGG CTGGAGGAAA AGTTGGGTGT GAACCTGCTC


 


151
AACCGCACCA CGCGGCAACT CAGTCTGACG GAAGAAGGCG CGCAATATTT


 


201
CCGCCGCGCG CAGAGAATCC TGCAAGAAAT GGCAGCGGCG GAAACCGAAA


 


251
TGCTGGCAGT GCACGAAATA CCGCAAGGCG TGTTGAGCGT GGATTCCGCG


 


301
ATGCCGATGG TGCTGCATCT GCTGGCGCCG CTGGCAGCAA AATTCAACGA


 


351
ACGCTATCCG CATATCCGAC TTTCGCTCGT TTCTTCCGAA GGCTATATCA


 


401
ATCTGATTGA ACGCAAAGTC GATATTGCCT TACGGGCCGG AGAATTGGAC


 


451
GATTCCGGGC TGCGTGCACG CCATCTGTTT GACAGCCGCT TCCGCGTAAT


 


501
CGCCAGTCCT GAATACCTGG CAAAACACGG CACGCCGCAA TCTACAGAAG


 


551
AGCTTGCCGG CCACCAATGT TTAGGCTTCA CCGAACCCGG TTCTCTAAAT


 


601
ACATGGGCGG TTTTAGATGC GCAGGGAAAT CCCTATAAGA TTTCACCGCA


 


651
CTTTACCGCC AGCAGCGGTG AAATCTTACG CTCGTTGTGC CTTTCAGGTT


 


701
GCGGTATTGT TTGCTTATCA GATTTTTTGG TTGACAACGA CATCGCTGAA


 


751
GGAAAGTTAA TTCCCCTGCT CGCCGAACAA ACCTCCGATA AAACACACCC


 


801
CTTTAATGCT GTTTATTACA GCGATAAAGC CGTCAATCTC CGCTTACGCG


 


851
TATTTTTGGA TTTTTTAGTG GAGGAACTGG GAAACAATCT CTGTGGATAA






This corresponds to the amino acid sequence <SEQ ID 658; ORF 158>:










m158.pep




1
MKTNSEELTV FVQVVESGSF SRAAEQLAMA NSAVSRIVKR LEEKLGVNLL


 


51
NRTTRQLSLT EEGAQYFRRA QRILQEMAAA ETEMLAVHEI PQGVLSVDSA


 


101
MPMVLHLLAP LAAKFNERYP HIRLSLVSSE GYINLIERKV DIALRAGELD


 


151
DSGLRARHLF DSRFRVIASP EYLAKHGTPQ STEELAGHQC LGFTEPGSLN


 


201
TWAVLDAQGN PYKISPHFTA SSGEILRSLC LSGCGIVCLS DFLVDNDIAE


 


251
GKLIPLLAEQ TSDKTHPFNA VYYSDKAVNL RLRVFLDFLV EELGNNLCG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m158/g158 94.3% identity in 297 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 659>:










a158.seq




1
ATGAAAACCA ATTCAGAAGA ACTGACCGTA TTTGTTCAAG TGGTGGAAAG


 


51
CGGCAGCTTC AGCCGTGCGG CGGAGCAGTT GGCGATGGCA AATTCTGCCG


 


101
TAAGCCGCAT CGTCAAACGG CTGGAGGAAA AGTTGGGTGT GAACCTGCTC


 


151
AACCGCACCA CGCGGCAACT CAGTCTGACG GAAGAAGGCG CGCAATATTT


 


201
CCGCCGCGCG CAGAGAATCC TGCAAGAAAT GGCAGCGGCG GAAACCGAAA


 


251
TGCTGGCAGT GCACGAAATA CCGCAAGGCG TGTTGCGCGT GGATTCCGCG


 


301
ATGCCGATGG TGCTGCATCT GCTGGCGCCG CTGGCAGCAA AATTCAACGA


 


351
ACGCTATCCG CATATCCGAC TTTCGCTCGT TTCTTCCGAA GGCTATATCA


 


401
ATCTGATTGA ACGCAAAGTC GATATTGCCT TACGGGCCGG AGAATTGGAC


 


451
GATTCCGGGC TGCGTGCACG CCATCTGTTT GACAGCCGCT TCCGCGTAAT


 


501
CGCCAGTCCT GAATACCTGG CAAAACACGG CACGCCGCAA TCTACAGAAG


 


551
AGCTTGCCGG CCACCAATGT TTAGGCTTCA CCGAACCCGG TTCTCTAAAT


 


601
ACATGGGCGG TTTTAGATGC GCAGGGAAAT CCCTATAAGA TTTCACCGCA


 


651
CTTTACCGCC AGCAGCGGTG AAATCTTACG CTCGTTGTGC CTTTCAGGTT


 


701
GCGGTATTGC TTGCTTATCA GATTTTTTGG TTGACAACGA CATCGCTGAA


 


751
GGAAAGTTAA TTCCCCTGCT CGCCGAACAA ACCTCCAATA AAACGCACCC


 


801
CTTTAATGCT GTTTATTACA GCGATAAAGC CGTCAACCTC CGCTTACGCG


 


851
TATTTTTGGA TTTTTTAGTG GAGGAACTGG GAAACAATCT CTGTGGATAA






This corresponds to the amino acid sequence <SEQ ID 660; ORF 158.a>:










a158.pep




1
MKTNSEELTV FVQVVESGSF SRAAEQLAMA NSAVSRIVKR LEEKLGVNLL


 


51
NRTTRQLSLT EEGAQYFRRA QRILQEMAAA ETEMLAVHEI PQGVLRVDSA


 


101
MPMVLHLLAP LAAKFNERYP HIRLSLVSSE GYINLIERKV DIALRAGELD


 


151
DSGLRARHLF DSRFRVIASP EYLAKHGTPQ STEELAGHQC LGFTEPGSLN


 


201
TWAVLDAQGN PYKISPHFTA SSGEILRSLC LSGCGIACLS DFLVDNDIAE


 


251
GKLIPLLAEQ TSNKTHPFNA VYYSDKAVNL RLRVFLDFLV EELGNNLCG*






m158/a158 99.0% identity in 299 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 661>:










g160.seq




1
ATGGAcattc tgGACAAact ggtcgatCTC GCccaATTGA CGGGCAGTGC


 


51
GGATGTGCAG TgcctTTTGG GCGGACAATG gcATGaaacc TTGCAACGCG


 


101
AAGGGCTGGT ACACATTGTT ACGGCGGGCA GCGGTTATCT CTGCATCGAC


 


151
GGCGAAACTT CCCCGCGTCC GGTCGGCACG GGCGATATTG TATTTTTCCC


 


201
GCGCGGCTTG GGTCATGTGT TGAGCCACGA CGGAAAATAC GGAGAAAGTT


 


251
TACAACCGGA CATACGACAA AACGGCACAT TTATGGTCAA ACAGTGCGGC


 


301
AACGGGCTGG ATATGAGCCT GTTTTGCGCC CGTTTCCGCT ACGACACCCA


 


351
CGCCGATTTG ATGAACGGGC TGCCGGAAAC CGTTTTTCTG AACATTGCCC


 


401
ATCCAAGTTT GCAGTATGTG GTTTCAATGC TGCAACTGGA AAGCGAAAAA


 


451
CCTTTGACGG GGACGGTTTC CGTGGTCAAC GCATTACCGT CCGTCCTGCT


 


501
GGTGCTTATC CTGCGCGCCT ATCTCGAACA GGATAAGGAT GTCGAACTCT


 


551
CGGGCGTATT GAAAGGTTGG CAGGACAAAC GTTTGGGACA TTTGATCCAA


 


601
AAGGTGATAG ACAAACCGGA AGACGAATGG AATATTGACA AAATGGTTGC


 


651
CGCCGCCAAT ATGTCGCGCG CGCAACTGAT GCGCCGCTTC AAAAGCCAAG


 


701
TCGGACTCAG CCCGCACGCC TTTGTGAACC ATATCCGCCT GCAAAAAGGC


 


751
GCATTGCTGC TGAAGAAAAC CCCGGATTCG GTTTTGGAGG TCGCGCTGTC


 


801
GGTGGGCTTT CAGTCGGAAA CGCATTTCGG CAAGGCGTTC AAACGGCAAT


 


851
ATCACGTTTC GCCGGGGCAA TACCGGAAAG AAGGCGGGCA AAAATAA






This corresponds to the amino acid sequence <SEQ ID 662; ORF 160.ng>:










g160.pep




1
MDILDKLVDL AQLTGSADVQ CLLGGQWHET LQREGLVHIV TAGSGYLCID


 


51
GETSPRPVGT GDIVFFPRGL GHVLSHDGKY GESLQPDIRQ NGTFMVKQCG


 


101
NGLDMSLFCA RFRYDTHADL MNGLPETVFL NIAHPSLQYV VSMLQLESEK


 


151
PLTGTVSVVN ALPSVLLVLI LRAYLEQDKD VELSGVLKGW QDKRLGHLIQ


 


201
KVIDKPEDEW NIDKMVAAAN MSRAQLMRRF KSQVGLSPHA FVNHIRLQKG


 


251
ALLLKKTPDS VLEVALSVGF QSETHFGKAF KRQYHVSPGQ YRKEGGQK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 663>:










m160.seq




1
ATGGACATTC TGGACAAACT GGTCGATTTC GCCCAATTGA CGGGCAGTGT


 


51
GGATGTGCAG TGCCTTTTGG GCGGACAATG GTCGGTACGG CATGAAACCT


 


101
TGCAACGCGA AGGATTGGTA CACATTGTTA CATCGGGCAG CGGCTATCTC


 


151
TGCATCGACG GCGAAACTTC CCCGCGTCCG GTCAGTACAG GGGATATTGT


 


201
ATTTTTCCCG CGCGGCTTGG GTCATGTGTT GAGCCACGAC GGAAAATGCG


 


251
GAGAAAGTTT ACAACCGGAT ATGCGGCAGC ACGGTGCGTT TACGGTCAAG


 


301
CAGTGCGGCA ACGGACAGGA TATGAGCCTG TTTTGCGCCC GTTTCCGCTA


 


351
CGACACCCAC GCCGATTTGA TGAACGGGCT GCCTGAAACC GTTTTTCTGA


 


401
ACATTGCCCA TCCGAGTTTA CAGTATGTGG TTTCAATGCT GCAACTGGAA


 


451
AGCAAAAAAC CTTTGACGGG GACGGTTTCC ATGGTCAACG CATTGTCGTC


 


501
CGTCCTGCTG GTGCTTATCC TGCGCGCCTA TCTCGAACAG GATAAGGATG


 


551
TCGAACTCTC GGGCGTATTG AAAGGTTGGC AGGACAAACG TTTGGGACAT


 


601
TTAATCCAAA AGGTGATAGA CAAACCGGAA GACGAATGGA ATGTCGACAA


 


651
AATGGTGGCG GCTGCCAATA TGTCGCGCGC GCAACTGATG CGCCGTTTCA


 


701
AAAGCCGGGT CGGACTCAGC CCGCACGCCT TTGTGAACCA TATCCGCCTG


 


751
CAAAAAGGCG CGTTGCTGCT GAAAAAAAAC CCGGATTCGG TTTTGTCGGT


 


801
CGCACTGTCG GTAGGCTTTC AGTCGGAAAC GCACTTCGGC AAGGCGTTCA


 


851
AACGGCAATA TCACGTTTCG CCGGGTCAAT ACCGGAAAGA AggCGGGCAA


 


901
AAATAA






This corresponds to the amino acid sequence <SEQ ID 664; ORF 160>:










m160.pep




1
MDILDKLVDF AQLTGSVDVQ CLLGGQWSVR HETLQREGLV HIVTSGSGYL


 


51
CIDGETSPRP VSTGDIVFFP RGLGHVLSHD GKCGESLQPD MRQHGAFTVK


 


101
QCGNGQDMSL FCARFRYDTH ADLMNGLPET VFLNIAHPSL QYVVSMLQLE


 


151
SKKPLTGTVS MVNALSSVLL VLILRAYLEQ DKDVELSGVL KGWQDKRLGH


 


201
LIQKVIDKPE DEWNVDKMVA AANMSRAQLM RRFKSRVGLS PHAFVNHIRL


 


251
QKGALLLKKN PDSVLSVALS VGFQSETHFG KAFKRQYHVS PGQYRKEGGQ


 


301
K*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m160/g160 93.4% identity in 301 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 665>:










a160.seq




1
ATGGACATTC TGGACAAACT GGTCGATTTC GCCCAATTGA CGGGCAGTGT


 


51
GGATGTGCAG TGCCTTTTGG GCGGACAATG GTCGGTACGG CATGAAACCT


 


101
TGCAACGCGA AGGATTGGTA CACATTGTTA CATCGGGCAG CGGCTATCTC


 


151
TGCATCGACG GCGAAACTTC CCCGCGTCCG GTCAGTACAG GGGATATTGT


 


201
ATTTTTCCCG CGCGGCTTGG GTCATGTGTT GAGCCACGAC GGAAAATGCG


 


251
GAGAAAGTTT ACAACCGGAT ATGCGGCAGC ACGGTGCGTT TACGGTCAAG


 


301
CAGTGCGGCA ACGGACAGGA TATGAGCCTG TTTTGCGCCC GTTTCCGCTA


 


351
CGACACCCAC GCCGATTTGA TGAACGGGCT GCCTGAAACC GTTTTTCTGA


 


401
ACATTGCCCA TCCGAGTTTA CAGTATGTGG TTTCAATGCT GCAACTGGAA


 


451
AGCAAAAAAC CTTTGACGGG GACGGTTTCC ATGGTCAACG CATTGTCGTC


 


501
CGTCCTGCTG GTGCTTATCC TGCGCGCCTA TCTCGAACAG GATAAGGATG


 


551
TCGAACTCTC GGGCGTATTG AAAGGTTGGC AGGACAAACG TTTGGGACAT


 


601
TTAATCCAAA AGGTGATAGA CAAACCGGAA GACGAATGGA ATGTCGACAA


 


651
AATGGTGGCG GCTGCCAATA TGTCGCGCGC GCAACTGATG CGCCGTTTCA


 


701
AAAGCCGGGT CGGACTCAGC CCGCACGCCT TTGTGAACCA TATCCGCCTG


 


751
CAAAAAGGCG CGTTGCTGCT GAAAAAAAAC CCGGATTCGG TTTTGTCGGT


 


801
CGCACTGTCG GTAGGCTTTC AGTCGGAAAC GCACTTCGGC AAGGCGTTCA


 


851
AACGGCAATA TCACGTTTCG CCGGGTCAAT ACCGGAAAGA AGGCGGGCAA


 


901
AAATAA






This corresponds to the amino acid sequence <SEQ ID 666; ORF 160.a>:










a160.pep




1
MDILDKLVDF AQLTGSVDVQ CLLGGQWSVR HETLQREGLV HIVTSGSGYL


 


51
CIDGETSPRP VSTGDIVFFP RGLGHVLSHD GKCGESLQPD MRQHGAFTVK


 


101
QCGNGQDMSL FCARFRYDTH ADLMNGLPET VFLNIAHPSL QYVVSMLQLE


 


151
SKKPLTGTVS MVNALSSVLL VLILRAYLEQ DKDVELSGVL KGWQDKRLGH


 


201
LIQKVIDKPE DEWNVDKMVA AANMSRAQLM RRFKSRVGLS PHAFVNHIRL


 


251
QKGALLLKKN PDSVLSVALS VGFQSETHFG KAFKRQYHVS PGQYRKEGGQ


 


301
K*






m160/a160 100.0% identity in 301 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 667>:










g161.seq




1
ATGGATACCG CAAAAAAAGA CATTTTAGGA TCGGGCTGGA TGCTGGTGGC


 


51
GGCGGCCTGC TTCACCGTTA TGAACGTATT GATTAAAGAG GCATCGGCAA


 


101
AATTTGCCCT CGGCAGCGGC GAATTGGTCT TTTGGCGCAT GCTGTTTTCA


 


151
ACCGTTACGC TCGGTGCTGC CGCCGTATTG CGGCGCGACA CCTTCCGCAC


 


201
GCCCCATTGG AAAAACCACT TAAACCGCAG TATGGTCGGG ACGGGGGCGA


 


251
TGCTGCTGCT GTTTTACGCG GTAACGCATC TGCCTTTGAC AACCGGCGTT


 


301
ACCCTGAGTT ACACCTCGTC GATTTTTttg GCGGTATTTT CCTTCCTGAT


 


351
TTTGAAAGAA CGGATTTCCG TTTACACGCA GGCGGTGCTG CTCCTTGGTT


 


401
TTGCCGGCGT GGTATTGCTG CTTAATCCCT CGTTCCGCAG CGGTCAGGAA


 


451
CCGGCGGCAC TCGCCGGGCT GGCGGGCGGC GCGATGTCCG GCTGGGCGTA


 


501
TTTGAAAGTG CGCGAACTGT CTTTGGCGGG CGAACCCGGC TGGCGCGTCG


 


551
TGTTTTACCT TTCCGCAACC GGCGTGGCGA TGTCGTCggt ttgggcgacg


 


601
Ctgaccggct ggCACAcccT GTCCTTTcca tcggcagttt ATCtgtCGGG


 


651
CATCGGCGTG tccgcgCtgA TTGCCCAaCT GtcgatgAcg cGCGcctaca


 


701
aaGTCGGCGA CAAATTCACG GTTGCCTCGC tttcctaTAt gaccgtcGTC


 


751
TTTTCCGCCC TGTCTGCCGC ATTTTTTCTg ggcgaagagc ttttctggCA


 


801
GGAAATACTC GGTATGTGCA TCATTATcct CAGCGGCATT TTGAGCAGCA


 


851
TCCGCCCCAT TGCCTTCAAA CAGCGGCTGC AAGCCCTCTT CCGCCAAAGA


 


901
TAA






This corresponds to the amino acid sequence <SEQ ID 668; ORF 161.ng>:










g161.pep




1
MDTAKKDILG SGWMLVAAAC FTVMNVLIKE ASAKFALGSG ELVFWRMLFS


 


51
TVTLGAAAVL RRDTFRTPHW KNHLNRSMVG TGAMLLLFYA VTHLPLTTGV


 


101
TLSYTSSIFL AVFSFLILKE RISVYTQAVL LLGFAGVVLL LNPSFRSGQE


 


151
PAALAGLAGG AMSGWAYLKV RELSLAGEPG WRVVFYLSAT GVAMSSVWAT


 


201
LTGWHTLSFP SAVYLSGIGV SALIAQLSMT RAYKVGDKFT VASLSYMTVV


 


251
FSALSAAFFL GEELFWQEIL GMCIIILSGI LSSIRPIAFK QRLQALFRQR


 


301
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 669>:










m161.seq




1
ATGGATACCG CAAAAAAAGA CATTTTAGGA TCGGGCTGGA TGCTGGTGGC


 


51
GGCGGCCTGC TTTACCATTA TGAACGTATT GATTAAAGAG GCATCGGCAA


 


101
AATTTGCCCT CGGCAGCGGC GAATTGGTCT TTTGGCGCAT GCTGTTTTCA


 


151
ACCGTTGCGC TCGGGGCTGC CGCCGTATTG CGTCGGGACA mCTTCCGCAC


 


201
GCCCCATTGG AAAAACCACT TAAACCGCAG TATGGTCGGG ACGGGGGCGA


 


251
TGCTGCTGCT GTTTTACGCG GTAACGCATC TGCCTTTGGC CACTGGCGTT


 


301
ACCCTGAGTT ACACCTCGTC GATTTTTTTG GCGGTATTTT CCTTCCTGAT


 


351
TTTGAAAGAA CGGATTTCCG TTTACACGCA GGCGGTGCTG CTCCTTGGTT


 


401
TTGCCGGCGT GGTATTGCTG CTTAATCCCT CGTTCCGCAG CGGTCAGGAA


 


451
ACGGCGGCAC TCGCCGGGCT GGCGGGCGGC GCGATGTCCG GCTGGGCGTA


 


501
TTTGAAAGTG CGCGAACTGT CTTTGGCGGG CGAACCCGGC TGGCGCGTCG


 


551
TGTTTTACCT TTCCGTGACA GGTGTGGCGA TGTCGTCGGT TTGGGCGACG


 


601
CTGACCGGCT GGCACACCCT GTCCTTTCCA TCGGCAGTTT ATCTGTCGTG


 


651
CATCGGCGTG TCCGCGCTGA TTGCCCAACT GTCGATGACG CGCGCCTACA


 


701
AAGTCGGCGA CAAATTCACG GTTGCCTCGC TTTCCTATAT GACCGTCGTT


 


751
TTTTCCGCTC TGTCTGCCGC ATTTTTTCTG GGCGAAGAGC TTTTCTGGCA


 


801
GGAAATACTC GGTATGTGCA TCATCATCCT CAGCGGTATT TTGAGCAGCA


 


851
TCCGCCCCAC TGCCTTCAAA CAGCGGCTGC AATCCCTGTT CCGCCAAAGA


 


901
TAA






This corresponds to the amino acid sequence <SEQ ID 670; ORF 161>:










m161.pep




1
MDTAKKDILG SGWMLVAAAC FTIMNVLIKE ASAKFALGSG ELVFWRMLFS


 


51
TVALGAAAVL RRDXFRTPHW KNHLNRSMVG TGAMLLLFYA VTHLPLATGV


 


101
TLSYTSSIFL AVFSFLILKE RISVYTQAVL LLGFAGVVLL LNPSFRSGQE


 


151
TAALAGLAGG AMSGWAYLKV RELSLAGEPG WRVVFYLSVT GVAMSSVWAT


 


201
LTGWHTLSFP SAVYLSCIGV SALIAQLSMT RAYKVGDKFT VASLSYMTVV


 


251
FSALSAAFFL GEELFWQEIL GMCIIILSGI LSSIRPTAFK QRLQSLFRQR


 


301
*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m161/g161 97.0% identity in 300 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 671>:










a161.seq




1
ATGGATACCG CAAAAAAAGA CATTTTAGGA TCGGGCTGGA TGCTGGTGGC


 


51
GGCGGCCTGC TTTACCATTA TGAACGTATT GATTAAAGAG GCATCGGCAA


 


101
AATTTGCCCT CGGCAGCGGC GAATTGGTCT TTTGGCGCAT GCTGTTTTCA


 


151
ACCGTTGCGC TCGGGGCTGC CGCCGTATTG CGTCGGGACA CCTTCCGCAC


 


201
GCCCCATTGG AAAAACCACT TAAACCGCAG TATGGTCGGG ACGGGGGCGA


 


251
TGCTGCTGCT GTTTTACGCG GTAACGCATC TGCCTTTGGC CACCGGCGTT


 


301
ACCCTGAGTT ACACCTCGTC GATTTTTTTG GCGGTATTTT CCTTCCTGAT


 


351
TTTGAAAGAA CGGATTTCCG TTTACACGCA GGCGGTGCTG CTCCTTGGTT


 


401
TTGCCGGCGT GGTATTGCTG CTTAATCCCT CGTTCCGCAG CGGTCAGGAA


 


451
ACGGCGGCAC TCGCCGGGCT GGCGGGCGGC GCGATGTCCG GCTGGGCGTA


 


501
TTTGAAAGTG CGCGAACTGT CTTTGGCGGG CGAACCCGGC TGGCGCGTCG


 


551
TGTTTTACCT TTCCGTGACA GGTGTGGCGA TGTCATCGGT TTGGGCGACG


 


601
CTGACCGGCT GGCACACCCT GTCCTTTCCA TCGGCAGTTT ATCTGTCGTG


 


651
CATCGGCGTG TCCGCGCTGA TTGCCCAACT GTCGATGACG CGCGCCTACA


 


701
AAGTCGGCGA CAAATTCACG GTTGCCTCGC TTTCCTATAT GACCGTCGTT


 


751
TTTTCCGCTC TGTCTGCCGC ATTTTTTCTG GCCGAAGAGC TTTTCTGGCA


 


801
GGAAATACTC GGTATGTGCA TCATCATCCT CAGCGGTATT TTGAGCAGCA


 


851
TCCGCCCCAC TGCCTTCAAA CAGCGGCTGC AATCCCTGTT CCGCCAAAGA


 


901
TAA






This corresponds to the amino acid sequence <SEQ ID 672; ORF 161.a>:










a161.pep




1
MDTAKKDILG SGWMLVAAAC FTIMNVLIKE ASAKFALGSG ELVFWRMLFS


 


51
TVALGAAAVL RRDTFRTPHW KNHLNRSMVG TGAMLLLFYA VTHLPLATGV


 


101
TLSYTSSIFL AVFSFLILKE RISVYTQAVL LLGFAGVVLL LNPSFRSGQE


 


151
TAALAGLAGG AMSGWAYLKV RELSLAGEPG WRVVFYLSVT GVAMSSVWAT


 


201
LTGWHTLSFP SAVYLSCIGV SALIAQLSMT RAYKVGDKFT VASLSYMTVV


 


251
FSALSAAFFL AEELFWQEIL GMCIIILSGI LSSIRPTAFK QRLQSLFRQR


 


301
*






m161/a161 99.3% identity in 300 aa overlap





The following partial DNA sentience was identified in N. gonorrhoea <SEQ ID 673>:










g163.seq




1
ATGGTTATTT TGACGACTTT GTTTTTTGTG TGTGTTTTGG TGGTATTGGT


 


51
TTTAACCGTG CCGGATCAGG TGCAGATGTG gctCGACCGG GCAAAAGAAG


 


101
TCATTTTTAC CGAGTTCAGC TGGTTTTATG TTTTAACGTT TTCCATTTTt


 


151
ctgGGTTTtc tgctGATACT CTCGGTCAGC GGTTTGGGAA ACATcagGCT


 


201
AGGACGGGAT GAAGATGTGC CGGAATTCGG CTTCCTGTCG TGGCTGGCGA


 


251
TGCTGTTTGC GGCCGGGATG GGCGTGGGCC TGATGTTTTT CGGCGTGGCA


 


301
GAGCCGTTGA TGCATTATTT TTCGGACATT ACGGTCGGCG CGCCGGAACA


 


351
CAGGCAGCAG CAGGCATTGC TGCACACGGT GTTCCATTGG GGCGTTCACG


 


401
CCTGGTCGGT GTACGGTACG ATTGCATTGG CTTTGGCTTA TTTCGGTTTC


 


451
CGCTACAAAC TGCCGCTTGC CCTGCGTTCT TGTTTTTACC CCCTGTTGAA


 


501
AGAAAAAATT TCCGGAAGGT TCGGCGATGC CATTGATATT ATGGCGTTGC


 


551
TTGCTACTTT TTTCGGCATC ATCACCACAT TGGGGTTCGG GGCTTCGCAA


 


601
CTGGGCGCCG GATTGCAGGA AATGGGCTGG ATTGCCGAAA ACAGCTTCGG


 


651
CGTGCAGGTC TTGATTATCG CCGCCGTAAT GTCCCTCGCC GTCGTTTCGG


 


701
CAATATCCGG CGTGGGGAAG GGCGTGAAGG TGTTGAGCGA GTTGAACCTG


 


751
GGCCTTGCGT TTTTGCTGCT GTTTTTTGTT TTGGCGGCGG ACCCCACTGT


 


801
TTACCTGTTG TCGGCATTCG GCGACAACAT AGGGAACTAC CTCGGAAATC


 


851
TGGTGCGCCT CAGTTTGAAA ACTTATGCGT ACGAACGGGA ACACAAGCCG


 


901
TGGTTTGAAT CTTGGACGGT GCTTTATTGG GCGTGGTGGT GTTCTTGGgc


 


951
gcCGTTTGTG GGTTTGTTTA TCGCGCGCAT TTCAAAGGGg cgcaccatCc


 


1001
gcgagtttgt CTTCGGGGTT TTGCTCATCC CCGGCCTGTT CGGCGTTTTG


 


1051
TGGTTTACCG TCTTCGGCAA TACGGCGATT TGGCTGAATG ACGGGGTTGC


 


1101
GGGGGGAATG CTCGAAAAGA TGACCTCCTC TCCGGAAACG CTGCTTTTTA


 


1151
AATTCTTTAA TTACCTCCCC CTGCCCGAAC TGACGAGCAT CGTCAGCCTG


 


1201
CTGGTCATTT CCCTGTTTTT TGTAACTTCT GCCGACTCCG GGATTTATGT


 


1251
CCTGAACAAT ATTACCTCTC GGGACAAAGG CTTGAGCGCG CCACGGTGGC


 


1301
AGGCGGTTAT GTGGGGCGTG CTGatgtcTG CCGTTGCCGT TTTGCTGATG


 


1351
CGCTCGGGCG GACTCGGCAA CCTGCAGTCT ATGACCCTGA TTGTTTCCCT


 


1401
GCCGTTTGCC CTGCTGATGC TGATAATGTG TTTCAGCCTG TGGAAAGGCT


 


1451
TGAGTGCGGA TAAGAAATAT TTTGAGACCC GGGTCAACCC TACCAGTGTA


 


1501
TTTTGGACGG GCGGCAAGTG GAAAGAACGG CTGGTGCGGA TAATGAGCCA


 


1551
GACGCAGGAG CAGGATATTT TAAAATTCCT CAAACATACC GCATCGCCCG


 


1601
CTATGCACGA GTTGCAACGG GAGCTTTCGG AAGAATACGG CTTGAGCGTC


 


1651
CGGGTCGATA AGATGTTTCA TCAGGACGAG CCCGCAATCG AGTTCGTCAT


 


1701
TCGGAAAGAG ACGATGCGCG ATTTTATGTA CGGGATTAAG TCTGTCGGGC


 


1751
AGGATGTATC CGACCAGTTG ATTAACGACG GCAAGCTGCC GCATATCCGG


 


1801
CACCAGACAA CTTACAAACC CTACGCTTAT TTTTTCGACG GGCGCGTCGG


 


1851
GTACGATGTG CAGTATATGA ACAAGGACGA GCTGATTGCC GACATTTTGA


 


1901
AAAACTACGA ACGTTATTTG ATGTTGTTGG ATGATGTCGG TCAGGAACTG


 


1951
ATGGCGCACG AGCAGGTGGA ATTGGCAGAG TAA






This corresponds to the amino acid sequence <SEQ ID 674; ORF 163.ng>:










g163.pep




1
MVILTTLFFV CVLVVLVLTV PDQVQMWLDR AKEVIFTEFS WFYVLTFSIF


 


51
LGFLLILSVS GLGNIRLGRD EDVPEFGFLS WLAMLFAAGM GVGLMFFGVA


 


101
EPLMHYFSDI TVGAPEHRQQ QALLHTVFHW GVHAWSVYGT IALALAYFGF


 


151
RYKLPLALRS CFYPLLKEKI SGRFGDAIDI MALLATFFGI ITTLGFGASQ


 


201
LGAGLQEMGW IAENSFGVQV LIIAAVMSLA VVSAISGVGK GVKVLSELNL


 


251
GLAFLLLFFV LAADPTVYLL SAFGDNIGNY LGNLVRLSLK TYAYEREHKP


 


301
WFESWTVLYW AWWCSWAPFV GLFIARISKG RTIREFVFGV LLIPGLFGVL


 


351
WFTVFGNTAI WLNDGVAGGM LEKMTSSPET LLFKFFNYLP LPELTSIVSL


 


401
LVISLFFVTS ADSGIYVLNN ITSRDKGLSA PRWQAVMWGV LMSAVAVLLM


 


451
RSGGLGNLQS MTLIVSLPFA LLMLIMCFSL WKGLSADKKY FETRVNPTSV


 


501
FWTGGKWKER LVRIMSQTQE QDILKFLKHT ASPAMHELQR ELSEEYGLSV


 


551
RVDKMFHQDE PAIEFVIRKE TMRDFMYGIK SVGQDVSDQL INDGKLPHIR


 


601
HQTTYKPYAY FFDGRVGYDV QYMNKDELIA DILKNYERYL MLLDDVGQEL


 


651
MAHEQVELAE *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 675>:










m163.seq




1
ATGGTTATTT TGACGACTTT GTTTTTTGTG TGTGTTTTGG TGGTATTGGT


 


51
TTTAACCGTG CCGGATCAGG TGCAGATGTG GCTCGATCGG GCAAAAGAAG


 


101
TCATTTTTAC CGAGTTCAGC TGGTTTTATG TTTTAACGTT TTCCATTTTT


 


151
CTGGGTTTCC TGCTGATACT CTCGGTCAGC AGTTTGGGAA ACATCAGGCT


 


201
CGGACGGGAT GAAGATGTGC CGGAATTCGG CTTCCTGTCG TGGCTGGCGA


 


251
TGCTGTTTGC GGCCGGGATG GGCGTGGGTC TGATGTTTTT CGGCGTGGCA


 


301
GAGCCGTTGA TGCATTATTT TTCGGACATT ACGGCCGGCA CGCCGGAACA


 


351
CAGGCAGCAG CAGGCATTGC TGCACACGGT GTTCCATTGG GGCGTTCACG


 


401
CTTGGTCGGT GTACGGTACG ATTGCATTGG CTTTGGCTTA TTTCGGTTTC


 


451
CGCTACAAGC TGCCGCTTGC CCTGCGTTCT TGTTTTTACC CCCTGTTGAA


 


501
AGAAAAAATT TCCGGAAGGT TCGGCGATGC CATTGATATT ATGGCGTTGC


 


551
TTGCTACTTT TTTCGGCATC ATCACCACAT TGGGGTTCGG GGCTTCGCAA


 


601
CTGGGCGCCG GATTGCAGGA AATGGGCTGG ATTGCCGAAA ACAGCTTCAG


 


651
CGTGCAGGTT TTGATTATCG CCGCCGTCAT GTCCCTCGCC GTCGTTTCGG


 


701
CAATATCCGG CGTGGGGAAG GGCGTGAAGG TGTTGAGCGA GTTGAACCTG


 


751
GGCCTTGCGT TTTTGCTGCT GTTTTTTGTT TTGGCGGCGG GACCCACTGT


 


801
TTACCTGTTG TCGGCATTCG GCGACAACAT AGGGAACTAC CTCGGAAATC


 


851
TGGTGCGCCT CAGTTTTAAA ACTTATGCGT ACGAACGGGA ACACAAGCCG


 


901
TGGTTTGAAT CTTGGACGGT GCTTTATTGG GCGTGGTGGT GTTCTTGGGC


 


951
GCCGTTTGTG GGTTTGTTTA TCGCGCGCAT TTCAAAGGGG CGCACCATCC


 


1001
GCGAGTTTGT CTTCGGGGTT TTGCTCATCC CCGGCCTGTT CGGCGTTTTG


 


1051
TGGTTTACCG TCTTCGGCAA TACGGCGATT TGGCTGAATG ACGGGGTTGC


 


1101
GGGGGGAATG CTCGAAAAGA TGACCTCCTC TCCGGAAACG CTGCTTTTTA


 


1151
AATTCTTTAA TTACCTCCCC CTGCCCGAAT TGACGAGCAT CGTCAGCCTG


 


1201
CTGGTCATTT CTCTGTTTTT TGTAACTTCT GCCGATTCCG GGATTTATGT


 


1251
CCTGAACAAT ATTACCTCTC GGGACAAAGG CTTGAGCGCG CCACGGTGGC


 


1301
AGGCGGTTAT GTGGGGCGTG CTGATGTCTG CCGTTGCCGT TTTGCTGATG


 


1351
CGCTCGGGCG GACTCGGCAA CCTGCAGTCT ATGACCCTGA TTGTTTCCCT


 


1401
GCCGTTTGCC CTGCTGATGC TGATAATGTG TTTCAGCCTG TGGAAAGGCT


 


1451
TGAGTGCGGA TAAGAAATAT TTTGAGACCC GGGTTAACCC TACCAGTGTA


 


1501
TTTTGGACGG GCGGCAAGTG GAAAGAACGG CTGGTGCAGA TAATGAGCCA


 


1551
GACGCAGGAG CAGGATATTT TAAAATTCCT CAAACAGACT GCATCGCCCG


 


1601
CTATGCACGA GTTGCAACGG GAGCTTTCGG AAGAATACGG CTTGAGCGTC


 


1651
CGGGTCGATA AAATGTTTCA TCGGGACGAG CCCGCAATCG AGTTCGTCAT


 


1701
TCGGAAAGAG ACGATGCGCG ATTTTATGTA CGGGATTAAG TCTGTCGGGC


 


1751
AGGATGTATC CGACCAGTTG ATTAACGACG GCAAGCTGCC GCATATCCGG


 


1801
CATCAGACAA CTTACAAACC CTACGCTTAT TTTTTCGACG GGCGCGTCGG


 


1851
GTACGATGTG CAGTATATGA ACAAGGACGA GCTGATTGCC GACATTTTGA


 


1901
AAAACTACGA ACGTTATTTG ATGTTGTTGG ATGATGTCGG TCAGGAACTG


 


1951
ATGGCGCACG AGCAGGTGGA ATTGGCAGAG TAA






This corresponds to the amino acid sequence <SEQ ID 676; ORF 163>:










m163.pep




1
MVILTTLFFV CVLVVLVLTV PDQVQMWLDR AKEVIFTEFS WFYVLTFSIF


 


51
LGFLLILSVS SLGNIRLGRD EDVPEFGFLS WLAMLFAAGM GVGLMFFGVA


 


101
EPLMHYFSDI TAGTPEHRQQ QALLHTVFHW GVHAWSVYGT IALALAYFGF


 


151
RYKLPLALRS CFYPLLKEKI SGRFGDAIDI MALLATFFGI ITTLGFGASQ


 


201
LGAGLQEMGW IAENSFSVQV LIIAAVMSLA VVSAISGVGK GVKVLSELNL


 


251
GLAFLLLFFV LAAGPTVYLL SAFGDNIGNY LGNLVRLSFK TYAYEREHKP


 


301
WFESWTVLYW AWWCSWAPFV GLFIARISKG RTIREFVFGV LLIPGLFGVL


 


351
WFTVFGNTAI WLNDGVAGGM LEKMTSSPET LLFKFFNYLP LPELTSIVSL


 


401
LVISLFFVTS ADSGIYVLNN ITSRDKGLSA PRWQAVMWGV LMSAVAVLLM


 


451
RSGGLGNLQS MTLIVSLPFA LLMLIMCFSL WKGLSADKKY FETRVNPTSV


 


501
FWTGGKWKER LVQIMSQTQE QDILKFLKQT ASPAMHELQR ELSEEYGLSV


 


551
RVDKMFHRDE PAIEFVIRKE TMRDFMYGIK SVGQDVSDQL INDGKLPHIR


 


601
HQTTYKPYAY FFDGRVGYDV QYMNKDELIA DILKNYERYL MLLDDVGQEL


 


651
MAHEQVELAE *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m163/g163 98.6% identity in 660 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 677>:










a163.seq




1
ATGGTTATTT TGACGACTTT GTTTTTTGTG TGTGTTTTGG TGGTATTGGT


 


51
TTTAACCGTG CCGGATCAGG TGCAGATGTG GCTCGATCGG GCAAAAGAAG


 


101
TCATTTTTAC CGAGTTCAGC TGGTTTTATG TTTTAACGTT TTCCATTTTT


 


151
CTGGGTTTCC TGCTGATACT CTCGGTCAGC AGTTTGGGAA ACATCAGGCT


 


201
CGGACGGGAT GAAGATGTGC CGGAATTCGG CTTCCTGTCG TGGCTGGCGA


 


251
TGCTGTTTGC GGCCGGGATG GGCGTGGGTC TGATGTTTTT CGGCGTGGCA


 


301
GAGCCGTTGA TGCATTATTT TTCGGACATT ACGGCCGGCA CGCCGGAACA


 


351
CAGGCAGCAG CAGGCATTGC TGCACACGGT GTTCCATTGG GGCGTTCACG


 


401
CTTGGTCGGT GTACGGTACG ATTGCATTGG CTTTGGCTTA TTTCGGTTTC


 


451
CGCTACAAGC TGCCGCTTGC CCTGCGTTCT TGTTTTTACC CCCTGTTGAA


 


501
AGAAAAAATT TCCGGAAGGT TCGGCGATGC CATTGATATT ATGGCGTTGC


 


551
TTGCTACTTT TTTCGGCATC ATCACCACAT TGGGGTTCGG GGCTTCGCAA


 


601
CTGGGCGCCG GATTGCAGGA AATAGGCTGG ATTGCCGAAA ACAGCTTCAG


 


651
CGTGCAGGTT TTGATTATCG CCGCCGTCAT GTCCCTCGCC GTCGTTTCGG


 


701
CAATATCCGG CGTGGGGAAG GGTGTGAAGG TGTTGAGCGA GTTGAACCTG


 


751
GGTCTTGCGT TTTTGCTGCT GTTTTTTGTT TTGGCGGCGG GTCCCACTGT


 


801
TTACCTGTTG TCGGCATTCG GCGACAACAT AGGGAACTAC CTCGGAAATC


 


851
TGGTGCGCCT CAGTTTTAAA ACTTATGCGT ACGAACGGGA ACACAAGCCG


 


901
TGGTTTGAAT CTTGGACGGT GCTTTATTGG GCGTGGTGGT GTTCTTGGGC


 


951
GCCGTTTGTG GGTTTGTTTA TCGCGCGCAT TTCAAAGGGG CGCACCATCC


 


1001
GCGAGTTTGT CTTCGGGGTT TTGCTCATCC CCGGCCTGTT CGGCGTTTTG


 


1051
TGGTTTACCG TCTTCGGCAA TACGCCGATT TGGCTGAATG ACGGGGTTGC


 


1101
GGGGGGAGTG CTCGAAAAGA TGACCTCCTC TCCGGAAACG CTGCTTTTTA


 


1151
AATTCTTTAA TTACCTCCCC CTGCCCGAAT TGACGAGCAT CGTCAGCCTG


 


1201
CTGGTCATTT CTCTGTTTTT TGTAACTTCT GCCGATTCCG GGATTTATGT


 


1251
CCTGAACAAT ATTACCTCTC GGGACAAAGG CTTGAGCGCG CCACGGTGGC


 


1301
AGGCGGTTAT GTGGGGCGTG CTGATGTCTG CCGTTGCCGT TTTGCTGATG


 


1351
CGCTCGGGCG GACTCGGCAA CCTGCAGTCT ATGACCCTGA TTGTTTCCCT


 


1401
GCCGTTTGCC CTGCTGATGC TGATAATGTG TTTCAGCCTG TGGAAAGGAT


 


1451
TGAGTGCGGA TAAGAAATAT TTTGAGACCC GGGTTAACCC TACCAGTGTA


 


1501
TTTTGGACGG GCGGCAAGTG GAAAGAACGG CTGGTGCAGA TAATGAGCCA


 


1551
GACGCAGGAG CAGGATATTT TAAAATTCCT CAAACATACC GCATCGCCCG


 


1601
CTATGCACGA GTTACAACGG GAGCTTTCGG AAGAATACGG CTTGAGCGTC


 


1651
CGGGTCGATA AGATGTTTCA TCAGGACGAG CCCGCAATCG AGTTCGTCAT


 


1701
TCGGAAAGAG ACGATGCGCG ATTTTATGTA CGGGATTAAG TCTGTCGGGC


 


1751
AGGATGTATC CGACCAGTTG ATTAACGACG GCAAGCTGCC GCATATCCGG


 


1801
CATCAGACAA CTTACAAACC CTACGCTTAT TTTTTCGACG GGCGCGTCGG


 


1851
GTACGATGTG CAGTATATGA ACAAGGACGA GCTGATTGCC GACATTTTGA


 


1901
AAAACTACGA ACGTTATTTG ATGTTGTTGG ATGATGTCGG TCAGGAACTG


 


1951
ATGGCGCACG AGCAGGTGGA ATTGGCAGAG TAA






This corresponds to the amino acid sequence <SEQ ID 678; ORF 163.a>:










a163.pep




1
MVILTTLFFV CVLVVLVLTV PDQVQMWLDR AKEVIFTEFS WFYVLTFSIF


 


51
LGFLLILSVS SLGNIRLGRD EDVPEFGFLS WLAMLFAAGM GVGLMFFGVA


 


101
EPLMHYFSDI TAGTPEHRQQ QALLHTVFHW GVHAWSVYGT IALALAYFGF


 


151
RYKLPLALRS CFYPLLKEKI SGRFGDAIDI MALLATFFGI ITTLGFGASQ


 


201
LGAGLQEIGW IAENSFSVQV LIIAAVMSLA VVSAISGVGK GVKVLSELNL


 


251
GLAFLLLFFV LAAGPTVYLL SAFGDNIGNY LGNLVRLSFK TYAYEREHKP


 


301
WFESWTVLYW AWWCSWAPFV GLFIARISKG RTIREFVFGV LLIPGLFGVL


 


351
WFTVFGNTAI WLNDGVAGGV LEKMTSSPET LLFKFFNYLP LPELTSIVSL


 


401
LVISLFFVTS ADSGIYVLNN ITSRDKGLSA PRWQAVMWGV LMSAVAVLLM


 


451
RSGGLGNLQS MTLIVSLPFA LLMLIMCFSL WKGLSADKKY FETRVNPTSV


 


501
FWTGGKWKER LVQIMSQTQE QDILKFLKHT ASPAMHELQR ELSEEYGLSV


 


551
RVDKMFHQDE PAIEFVIRKE TMRDFMYGIK SVGQDVSDQL INDGKLPHIR


 


601
HQTTYKPYAY FFDGRVGYDV QYMNKDELIA DILKNYERYL MLLDDVGQEL


 


651
MAHEQVELAE *






m163/a163 99.4% identity in 660 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 679>:









g164.seq (partial)










1
..ATGAACACAT TTTTGAAAAA CAGCGAATAC GCGTATATCC TGAACGACTG



 


51
  CAAGGCGCGC TTCCTGTTCG CCTCGGCCGG CCTGTCAAAA GAATTGGCGG


 


101
  GCCTGAAGGC GCAAACGCCC GTCGAAAAAA TCATTTGGAC GGACAAAAGC


 


151
  CGGCCGGCCG GCGAAACGGC GGAAGGCGAT GCCTTTTTTG AAAACGTGCG


 


201
  CCGCTTCCCC GAAAAACCCG ACTTGGGCCG CCAACCCCGG ATAAATGATT


 


251
  TGGCACACAT CATCTACACC TCCGGCACGA CGGGGCATCC CAAAGGCGCG


 


301
  CTAATCAGTT ACGCCAACCT GTTCGCCAAC CTGAACGGCA TCGAACGCAT


 


351
  CTTtaaAATT TCCAAACGCG ACCGCTTTAT CGTTTTCctg ccgatgTTCC


 


401
  ACAGCTTCAC GCTGACGGCT ATGGTGCTGC TGCCGATTTA TATGGCGTGT


 


451
  TCGATTATTT TGGTCAAAtc cgttttCCCc ttttccaacG TTTTGAAACA


 


501
  GGCCCTGCTC AAACGCGCAA CCGTGTTTTT GGGCGTACCC GCGATTTACA


 


551
  CCGCGATGAG CAAGGCAAAA ATCCCTTGGT ATTTCAGATG GTTCAACCGC


 


601
  ATCCGCCTGT TTATCAGCGG CGGCGCGCCT TTGGCGGAAC AAACCATCCT


 


651
  CGATTTTAAA GCCAAGTTCC CCCGCGCCAA ATTGCTGGAA GGCTACGGAC


 


701
  TGAGCGAAGC CTCGCCCGTC GTCGCCGTCA ATACGCCCGA ACGGCAAAAA


 


751
  GCCCGCAGCG TCGGCATCCC CCTGCCCGGT TTGGAAGCCA AAGCCGTCGA


 


801
  TGAAGAATTG GTCGAAGTGC CGCGCGGCGA AGTGGGCGAA CTGATCGTCA


 


851
  GGGGCGGTTC GGTGATGCGG GGCTACCTCA ATATGCCTGC CGCCACCGAT


 


901
  GAAACCATCG TCAACGGCTG GTTGAAAACG GGCGATTTCG TTACCATAGA


 


951
  CGAGGACGGC TTTATCTTTA TCGTCGACCG CAAAAAAGAT TTGATTATTT


 


1001
  CCAAAGGTCA AAACGTCTAT CCGCGCGAGA TCGAAGAAGA AATCCACAAA


 


1051
  CTCGATGCCG TCGAAGCCGC CGCCGTCATC GGCGTGAAAG ACCGTTATGC


 


1101
  CGACGAGGAA ATCGTCGCCT TCGTCCAATT GAAGGAAGGT ATGGATTTGG


 


1151
  GCGAGGACGA aatccgccgc caccTGCGTA CCGTGCTGGC AAATTTCAAA


 


1201
  ATCCCCAAAC AGATCCACTT TAAAGACGGG CTGCCGCGCA ACGCTACGGG


 


1251
  CAAAGTATTG AAACGGGTGC TGAAGGAGCA GTTTGAAGGA AACAAATGA






This corresponds to the amino acid sequence <SEQ ID 680; ORF 164.ng>:









g164.pep (partial)










1
..MNTFLKNSEY AYILNDCKAR FLFASAGLSK ELAGLKAQTP VEKIIWTDKS



 


51
  RPAGETAEGD AFFENVRRFP EKPDLGRQPR INDLAHIIYT SGTTGHPKGA


 


101
  LISYANLFAN LNGIERIFKI SKRDRFIVFL PMFHSFTLTA MVLLPIYMAC


 


151
  SIILVKSVFP FSNVLKQALL KRATVFLGVP AIYTAMSKAK IPWYFRWFNR


 


201
  IRLFISGGAP LAEQTILDFK AKFPRAKLLE GYGLSEASPV VAVNTPERQK


 


251
  ARSVGIPLPG LEAKAVDEEL VEVPRGEVGE LIVRGGSVMR GYLNMPAATD


 


301
  ETIVNGWLKT GDFVTIDEDG FIFIVDRKKD LIISKGQNVY PREIEEEIHK


 


351
  LDAVEAAAVI GVKDRYADEE IVAFVQLKEG MDLGEDEIRR HLRTVLANFK


 


401
  IPKQIHFKDG LPRNATGKVL KRVLKEQFEG NK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 681>:










m164.seq




1
ATGAACCGGA CTTATGCCAA TTTCTACGAA ATGCTCGCCG CCGCCTGCCG


 


51
CAAAAACGGA AACGGCACGG CAGTGTTCGA CGGCAAGGAA AAAACCGCCT


 


101
ACCGCGCGCT CAAGCAGGAG GCCGAAGCCG TCGCGGCGTA TCTGCAAAAT


 


151
ATCGGCGTGA AGTTCGGCGA CACGGTCGCG CTGGCGGTTT CCAATTCCAC


 


201
AGAATTTATT ACCGCCTATT TCGCCATCTC CGCCATCGGC GCGGTCGCCG


 


251
TACCGATGAA CACATTTTTG AAAAACAGCG AATACGCGTA TATCCTGAAC


 


301
GACTGCAAGG CGCGCTTCCT GTTCGCCTCG GCCGGCCTGT CAAAAGAATT


 


351
GGCGGGCTTG AAGGCGCAAA CGCCCGTCGA AAAAATCATT TGGACGGACA


 


401
AAAGCCGTCC GACCGGCGAA ACGGCGGAAG GCGATGCCTT TTTTGAAGAC


 


451
GTGCGCCGCT TCCCCGAAAA ACCCGACTTG GGCCGCCAAC CCCGGATAAA


 


501
TGATTTGGCA CACATCATCT ACACCTCCGG CACGACGGGG CATCCCAAAG


 


551
GCGCGCTAAT CAGTTACGCC AACCTGTTCG CCAACCTGAA CGGCATCGAA


 


601
CGCATCTTTA AAATTTCCAA GCGCGACCGC TTTATCGTTT TCCTGCCGAT


 


651
GTTCCACAGC TTCACGCTGA CGGCTATGGT GCTGCTGCCG ATTTATATGG


 


701
CGTGTTCGAT TATTTTGGTC AAATCCGTTT TTCCGTTTTC CAACGTTTTG


 


751
AAACAGACAC TGCTCAAACG CGCGACCGTG TTTTTGGGCG TACCCGCGAT


 


801
TTACACCGCG ATGAGCAAGG CGAAAATCCC TTGGTATTTC AGATGGTTCA


 


851
ACCGCATTCG CCTGTTTATC AGCGGCGGCG CGCCTTTGGC GGAACAAACC


 


901
ATCCTCGATT TCAAAGCCAA GTTCCCCCGC GCCAAATTGC TGGAAGGCTA


 


951
CGGACTGAGC GAAGCCTCTC CCGTCGTCGC CGTCAATACG CCCGAGAGGC


 


1001
AAAAAGCCCG CAGCGTCGGC ATCCCCCTGC CCGGTTTGGA AGCCAAAGCC


 


1051
GTCGATGAAG AATTGGTCGA AGTGCCGCGC GGCGAAGTGG GCGAACTGAT


 


1101
CGTCAGGGGC GGTTCGGTGA TGCGGGGCTA CCTCAATATG CCTGCCGCCA


 


1151
CCGATGAAAC CATCGTCAAC GGCTGGTTGA AAACGGGCGA TTTCGTTACC


 


1201
ATAGACGAAG ACGGCTTTAT CTTTATCGTC GACCGCAAAA AAGATTTGAT


 


1251
TATTTCCAAA GGTCAAAATG TCTATCCGCG CGAGATTGAA GAAGAAATCT


 


1301
ACAAACTCGA TGCCGTCGAA GCCGCCGCCG TCATCGGCGT GAAAGACCGT


 


1351
TATGCCGACG AGGAAATCGT CGCCTTCGTC CAATTGAAGG AAGGTATGGA


 


1401
TTTGGGCGAG AACGAAATCC GCCGCCACCT GCGTACCGTG CTGGCAAATT


 


1451
TCAAAATCCC CAAACAAATC CACTTTAAAG ACGGGCTGCC GCGCAACGCT


 


1501
ACGGGCAAGG TATTGAAACG GGTGTTGAAG GAGCAGTTTG ACGGAAACAA


 


1551
ATGA






This corresponds to the amino acid sequence <SEQ ID 682; ORF 164>:










m164.pep




1
MNRTYANFYE MLAAACRKNG NGTAVFDGKE KTAYRALKQE AEAVAAYLQN


 


51
IGVKFGDTVA LAVSNSTEFI TAYFAISAIG AVAVPMNTFL KNSEYAYILN


 


101
DCKARFLFAS AGLSKELAGL KAQTPVEKII WTDKSRPTGE TAEGDAFFED


 


151
VRRFPEKPDL GRQPRINDLA HIIYTSGTTG HPKGALISYA NLFANLNGIE


 


201
RIFKISKRDR FIVFLPMFHS FTLTAMVLLP IYMACSIILV KSVFPFSNVL


 


251
KQTLLKRATV FLGVPAIYTA MSKAKIPWYF RWFNRIRLFI SGGAPLAEQT


 


301
ILDFKAKFPR AKLLEGYGLS EASPVVAVNT PERQKARSVG IPLPGLEAKA


 


351
VDEELVEVPR GEVGELIVRG GSVMRGYLNM PAATDETIVN GWLKTGDFVT


 


401
IDEDGFIFIV DRKKDLIISK GQNVYPREIE EEIYKLDAVE AAAVIGVKDR


 


451
YADEEIVAFV QLKEGMDLGE NEIRRHLRTV LANFKIPKQI HFKDGLPRNA


 


501
TGKVLKRVLK EQFDGNK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae m164/g164 98.6% identity in 432 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 683>:










a164.seq




1
ATGAACCGGA CTTATGCCAA TTTCTACGAA ATGCTGACCG CCGCCTGCCG


 


51
CAAAAACGGC AACGGCACGG CAGTGTTCGA CGGCAAGGAA AAAACCGCCT


 


101
ACCGCGCGCT CAAGCAGGAA GCCGAAGCCG TTGCGGCGTA TCTGCAAAAT


 


151
ATCGGCGTGA AGTTCGGCGA CACGGTCGCG CTGGCGGTTT CCAATTCCAC


 


201
GGAATTTATT ACCGCCTATT TCGCCGTATC CGCCATCGGC GCGGTTGCCG


 


251
TACCGATGAA CACATTTTTG AAAAACAGCG AATACGCGTA TATCCTGAAC


 


301
GACTGCAAGG CGCGCTTCCT GTTCGCCTCG GCCGGCCTGT CAAAAGAATT


 


351
GGCGGGCTTG AAGGCGCAAA CGCCCGTCGA AAAAATCATT TGGACGGGCC


 


401
AAAGCCGTCC GGACGGCGAA ATGGCGGAAG GCGATGCCTT TTTTGAAGAC


 


451
GTGCGCCGCT TCCCCGAAAA ACCCGACTTG GGCCGCCAAC CCCGGATAAA


 


501
TGATTTGGCA CACATCATCT ACACCTCCGG CACGACGGGG CATCCCAAAG


 


551
GTGCGCTAAT CAGCTACGCC AACCTGTTCG CCAACCTGAA CGGCATCGAA


 


601
CGCATCTTTA AAATCTCCAA GCGCGACCGC TTTATCGTTT TCCTGCCGAT


 


651
GTTCCACAGC TTCACGCTGA CGGCTATGGT GCTGCTGCCG ATTTATATGG


 


701
CGTGTTCGAT TATTTTGGTC AAATCCGTTT TCCCCTTTTC CAACGTTTTG


 


751
AAACAGGCAC TGCTCAAACG CGCGACCGTG TTTTTGGGCG TGCCCGCGAT


 


801
TTACACCGCG ATGAGCAAGA CGAAAATCCC TTGGTATTTC AGATGGTTCA


 


851
ACCGCATCCG CCTGTTTATC AGCGGCGGAG CACCTTTGGC GGAACAAACC


 


901
ATCCTCGATT TCAAAGCCAA GTTCCCCCGC GCCAAATTGC TGGAAGGCTA


 


951
CGGACTGAGC GAAGCCTCGC CCGTCGTCGC CGTCAATACG CCCGAGAGGC


 


1001
AAAAAGCCCG CAGCGTCGGC ATCCCCCTGC CCGGTTTGGA AGTCAAAGCC


 


1051
GTCGATGAAG AATTGGTCGA AGTGCCGCGC GGCGAAGTGG GCGAACTGAT


 


1101
CGTCAGGGGC GGTTCGGTGA TGCGGGGCTA CCTCAATATG CCTGCCGCCA


 


1151
CCGATGAAAC CATCGTCAAC GGCTGGTTGA AAACGGGCGA TTTCGTTACC


 


1201
ATAGACGAAG ACGGCTTTAT CTTTATCGTC GACCGCAAAA AAGATTTGAT


 


1251
TATTTCCAAA GGTCAAAATG TCTATCCGCG CGAAATCGAA GAAGAAATCT


 


1301
ACAAACTCGA TGCCGTCGAA GCCGCCGCCG TCATCGGCGT GAAAGACCGT


 


1351
TATGCCGACG AGGAAATCGT CGCCTTCGTC CAATTGAAGG AAGGTATGGA


 


1401
TTTGGGCGAG AACGAAATCC GCCGCCACCT GCGTACCGTG CTGGCAAATT


 


1451
TCAAAATCCC CAAACAAATC CACTTTAAAG ACGGGCTGCC GCGCAACGCT


 


1501
ACGGGCAAGG TATTGAAACG GGTGTTGAAG GAGCAGTTTG ACGGAAACAA


 


1551
ATGA






This corresponds to the amino acid sequence <SEQ ID 684; ORF 164.a>:










a164.pep




1
MNRTYANFYE MLTAACRKNG NGTAVFDGKE KTAYRALKQE AEAVAAYLQN


 


51
IGVKFGDTVA LAVSNSTEFI TAYFAVSAIG AVAVPMNTFL KNSEYAYILN


 


101
DCKARFLFAS AGLSKELAGL KAQTPVEKII WTGQSRPDGE MAEGDAFFED


 


151
VRRFPEKPDL GRQPRINDLA HIIYTSGTTG HPKGALISYA NLFANLNGIE


 


201
RIFKISKRDR FIVFLPMFHS FTLTAMVLLP IYMACSIILV KSVFPFSNVL


 


251
KQALLKRATV FLGVPAIYTA MSKTKIPWYF RWFNRIRLFI SGGAPLAEQT


 


301
ILDFKAKFPR AKLLEGYGLS EASPVVAVNT PERQKARSVG IPLPGLEVKA


 


351
VDEELVEVPR GEVGELIVRG GSVMRGYLNM PAATDETIVN GWLKTGDFVT


 


401
IDEDGFIFIV DRKKDLIISK GQNVYPREIE EEIYKLDAVE AAAVIGVKDR


 


451
YADEEIVAFV QLKEGMDLGE NEIRRHLRTV LANFKIPKQI HFKDGLPRNA


 


501
TGKVLKRVLK EQFDGNK*






m164/a164 98.3% identity in 517 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 685>:










g165.seq




1
ATGGCTGAAG CGACAGACGT TGTCTTGGTG GGCGGCGGCA TTATGAGCGC


 


51
GACTTTGGGC GTTTTGCTCA AAGAACTCGA ACCGTCTTGG GAAATCACCC


 


101
TGATTGAACG CTTGGAagat gTGGCGTTGG AATCGTCAAA cGCGTGGAAC


 


151
AACGcCGgca CGGGGCATTC CGcGCTGTGc GAATTGAACT AtgcgccGCT


 


201
GGGtgcggac ggcgtcatCA ATCCGGCGCg cgCCCTGAAT ATTGCCGAAC


 


251
AGTTTCATGT CAGCCGCCAG TTTTGGGcga cgctgGTCGC GGAAGGCAAG


 


301
TTGGAagaCA ATTCCTTCAT CAATGCcgtg ccgcatatGT Ctttggtgat


 


351
gAacgaagac cactgCCgtt acCTGCAAAA ACGCTATGAT GTGTTTAAAA


 


401
CGCAGAAACT TTTTGAAAAT ATGGAATTTT CCACCGATCG GAACAAAATT


 


451
TCCGATTGGG CtccgCTGAT TATGCGCGGC CGGgacgaaA ACCAACCCGT


 


501
CGCCGCCAAC TATTCCGCCG Aaggcacgga tgtcgATTTC GGACGGCTGA


 


551
CGCGCCAGAT GGTGAAATAT TTGCAGGGCA AGGGCGTAAA AACCGAGTTC


 


601
AACCGCCACG TCGAAGACAT CAAACGCGAA TCCGACGGCG CGTGGGTGCT


 


651
CAAAACCGCC GATACCCGCA ACCCAGACTG GCAGCTCACC CTCCGCACCC


 


701
GCTTCCTCTT CCTCGGCGCG GGCGGCGGCG CACTGACCCT GCTGCAAAAA


 


751
TCCGGCATCC CCGAAGGCAA AGGCTACGGC GGCTTACCCG TGTCCGGCCT


 


801
GTTCTTCCGC AACAGCAACC CCGAAACCGC CGAACAACAC AACGCCAAAG


 


851
TGTACGGGCA GGCTTCCGTC GGCGCGCCGC CGATGTCCGT CCCGCACCTC


 


901
GACACACGCA ACGTAGACGG CAAACGACAC CTTATGTTCG GTCCTTACGC


 


951
AGGTTTCCGT TCCAACTTCC TCAAGCAAGG CTCGTTTATG GATTTGCCGC


 


1001
TGTCCATCCA TATGGACAAC CTCTATCCTA TGCTGCGCGC CGGCTGGGCG


 


1051
AATATGCCGC TGACCAAATA CcTGCTGGgC gAaTTGCgtt aa






This corresponds to the amino acid sequence <SEQ ID 686; ORF 165.ng>:










g165.pep




1
MAEATDVVLV GGGIMSATLG VLLKELEPSW EITLIERLED VALESSNAWN


 


51
NAGTGHSALC ELNYAPLGAD GVINPARALN IAEQFHVSRQ FWATLVAEGK


 


101
LEDNSFINAV PHMSLVMNED HCRYLQKRYD VFKTQKLFEN MEFSTDRNKI


 


151
SDWAPLIMRG RDENQPVAAN YSAEGTDVDF GRLTRQMVKY LQGKGVKTEF


 


201
NRHVEDIKRE SDGAWVLKTA DTRNPDWQLT LRTRFLFLGA GGGALTLLQK


 


251
SGIPEGKGYG GLPVSGLFFR NSNPETAEQH NAKVYGQASV GAPPMSVPHL


 


301
DTRNVDGKRH LMFGPYAGFR SNFLKQGSFM DLPLSIHMDN LYPMLRAGWA


 


351
NMPLTKYLLG ELR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 687>:









m165.seq (partial)










1
ATGGCTGAAG CGACAGACGT TGTCTTGGTG GGCGGCGGCA TTATGAGCGC



 


51
GACTTTGGGC GTTTTGCTCA AAGAACTCGA ACCGTCTTGG GAAATCACCC


 


101
TGATTGAACG CTTGGAAGAT GTGGCGTTGG AATCGTCAAA CGCGTGGAAC


 


151
AACGCCGGCA CGGGGCATTC CGCGCTGTGC GAATTGAACT ATGCGCCGTT


 


201
GGGTGCAAAT GGGATTATCG ATCCGGCGCG CGCCCTCAAT ATTGCCGAAC


 


251
AGTTTCATGT CAGCCGCCAG TTTTGGGCGA CGCTGGTCGC GGAAGGCAAG


 


301
TTGGAAGACA ATTCCTTCAT CAATGCCGTG CCGCATATGT CTTTGGTGAT


 


351
GAATGAAGAC CATTGTTCTT ATCTTCAAAA ACGTTATGAC GCGTTTAAAA


 


401
CCCAAAAACT TTTTGAAAAT ATGGAATTTT CCACCGATCG GAACAAAATT


 


451
TCCGATTGGG CTCCGCTGAT GATGCGCGGC CGGGACGAAA ACCAACCCGT


 


501
CGCCGCCAAC TACTCCGCCG AAGgTACGGA TGTCGATTTC GGACGGCTGA


 


551
CGCGCCAAAT GGTGAAATAT TTGCAGGGCA AGGGCGTAAA AACCGAGTTC


 


601
AACCGCCACG TCGAAGACAT CAAACGCGAA TCCGACGGCG CGTGGGTGCT


 


651
CAAAACCGCC GATACCCGCA ACCCCGACGG GCAGCTCACC CTCCGTACCC


 


701
GCTTCCTCTT CCTCGGCGCG GGCGGCGGCG CGCTGACCCT GCTGCAAAAA


 


751
TCCGGCATCC CCGAAGGCAA AGGCTACGGC GGCTTCCCCG TGTCCGGCCT


 


801
GTTCTTCCGC AACAGCAACC CCGAAACCGC CGAACAACAC AACGCCAAAG


 


851
TGTACGGGCA GGCTTCCGTC GGCGCGCCGC CGATGTCCGT CCCGCACCTC


 


901
GACACACGCA ACGTGGACGG CAAACGCCAC CTTATGTTCG GCCCTTACGC


 


951
AGGCTTCCGT TCCAACTTCC TCAAGCAAGG CTCGCTTATG GATTTGCCGC


 


1001
TGTCCATCCA TATGGACAAC CTCTATCCTA TGCTGTGCGC CGGCTGGGCG


 


1051
AATATGCCGC TGACCAAA...






This corresponds to the amino acid sequence <SEQ ID 688; ORF 165>:









m165.pep (partial)










1
MAEATDVVLV GGGIMSATLG VLLKELEPSW EITLIERLED VALESSNAWN



 


51
NAGTGHSALC ELNYAPLGAN GIIDPARALN IAEQFHVSRQ FWATLVAEGK


 


101
LEDNSFINAV PHMSLVMNED HCSYLQKRYD AFKTQKLFEN MEFSTDRNKI


 


151
SDWAPLMMRG RDENQPVAAN YSAEGTDVDF GRLTRQMVKY LQGKGVKTEF


 


201
NRHVEDIKRE SDGAWVLKTA DTRNPDGQLT LRTRFLFLGA GGGALTLLQK


 


251
SGIPEGKGYG GFPVSGLFFR NSNPETAEQH NAKVYGQASV GAPPMSVPHL


 


301
DTRNVDGKRH LMFGPYAGFR SNFLKQGSLM DLPLSIHMDN LYPMLCAGWA


 


351
NMPLTK...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m165/g165 97.2% identity in 356 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 689>:










a165.seq




1
ATGGCTGAAG CGACAGACGT TGTCTTGGTG GGCGGCGGCA TTATGAGCGC


 


51
GACTTTGGGC GTTTTGCTCA AAGAACTCGA ACCGTCTTGG GAAATCACCC


 


101
TGATTGAACG CTTGGAAGAT GTGGCGTTGG AATCGTCAAA CGCGTGGAAC


 


151
AACGCCGGCA CGGGGCATTC CGCGCTGTGC GAATTGAACT ATGCGCCGTT


 


201
GGGTGCAAAT GGGATTATCG ATCCGGCGCG CGCCCTCAAT ATTGCCGAAC


 


251
AGTTTCATGT CAGCCGCCAG TTTTGGGCGA CGTTGGTCGC GGAAGGCAAG


 


301
TTGGAAGACA ATTCCTTCAT CAATGCCGTG CCGCATATGT CTTTGGTGAT


 


351
GAATGAAGAC CATTGTTCTT ATCTTCAAAA ACGTTATGAC GCGTTTAAAA


 


401
CCCAAAAACT TTTTGAAAAT ATGGAATTTT CCACCGATCG GAACAAAATT


 


451
TCCGATTGGG CTCCGCTGAT GATGCGCGGC CGGGACGAAA ACCAACCCGT


 


501
CGCCGCCAAC TACTCCGCCG AAGGCACGGA TGTCGATTTC GGACGGCTGA


 


551
CGCGCCAAAT GGTGAAATAT TTGCAGGGCA AGGGCGTAAA AACCGAGTTC


 


601
AACCGCCACG TCGAAGACAT CAAACGCGAA TCCGACGGCG CGTGGGTGCT


 


651
CAAAACCGCC GATACCCGCA ACCCCGACGG GCAGCTCACC CTCCGTACCC


 


701
GCTTCCTCTT CCTCGGCGCG GGCGGCGGCG CGCTGACCCT GCTGCAAAAA


 


751
TCCGGCATCC CCGAAGGCAA AGGCTACGGT GGCTTTCCCG TGTCCGGCCT


 


801
GTTCTTCCGC AACAGCAACC CCGAAACCGC CGAACAACAC AACGCCAAAG


 


851
TGTACGGGCA GGCTTCCGTC GGCGCGCCGC CGATGTCCGT CCCGCACCTC


 


901
GACACACGCA ACGTGGACGG CAAACGCCAC CTTATGTTCG GCCCTTACGC


 


951
AGGCTTCCGT TCCAACTTCC TCAAGCAAGG CTCACTTATG GATTTGCCGC


 


1001
TGTCCATCCA TATGGACAAC CTCTATCCTA TGCTGCGCGC CGGCTGGGCG


 


1051
AATATGCCGC TGACCAAATA CCTGCTGGGC GAATTGCGTA AAACCAAAGA


 


1101
AGAACGCTTC GCCTCCCTGC TGGAATACTA CCCCGAGGCA AACCCCGACG


 


1151
ACTGGGAACT CATCACCGCA GGGCAACGCG TTCAAATCAT TAAAAAAGAC


 


1201
TCCGAAAAAG GCGGCGTGTT GCAGTTTGGT ACGGAGATTG TCGCACACGC


 


1251
CGACGGCTCG CTCGCCGCAT TGCTGGGCGC GTCGCCGGGC GCATCGACCG


 


1301
CCGTGCCGCT GATGATCCGG CTGATGCACC AATGCTTCCC CGAACGCACC


 


1351
CCGTCTTGGG AAGGCCGTCT GAAAGAGCTG GTACCGGGTT ACGGCATCAA


 


1401
GTTGAACGAA AACCCCGAAA GGGCGGATGA AATTATCGCC TATACCGCGA


 


1451
AAGTGTTGGA TATTTAA






This corresponds to the amino acid sequence <SEQ ID 690; ORF 165.a>:










a165.pep




1
MAEATDVVLV GGGIMSATLG VLLKELEPSW EITLIERLED VALESSNAWN


 


51
NAGTGHSALC ELNYAPLGAN GIIDPARALN IAEQFHVSRQ FWATLVAEGK


 


101
LEDNSFINAV PHMSLVMNED HCSYLQKRYD AFKTQKLFEN MEFSTDRNKI


 


151
SDWAPLMMRG RDENQPVAAN YSAEGTDVDF GRLTRQMVKY LQGKGVKTEF


 


201
NRHVEDIKRE SDGAWVLKTA DTRNPDGQLT LRTRFLFLGA GGGALTLLQK


 


251
SGIPEGKGYG GFPVSGLFFR NSNPETAEQH NAKVYGQASV GAPPMSVPHL


 


301
DTRNVDGKRH LMFGPYAGFR SNFLKQGSLM DLPLSIHMDN LYPMLRAGWA


 


351
NMPLTKYLLG ELRKTKEERF ASLLEYYPEA NPDDWELITA GQRVQIIKKD


 


401
SEKGGVLQFG TEIVAHADGS LAALLGASPG ASTAVPLMIR LMHQCFPERT


 


451
PSWEGRLKEL VPGYGIKLNE NPERADEIIA YTAKVLDI*






m165/a165 99.7% identity in 356 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 691>:










g165-1.seq




1
ATGGCTGAAG CGACAGACGT TGTCTTGGTG GGCGGCGGCA TTATGAGCGC


 


51
GACTTTGGGC GTTTTGCTCA AAGAACTCGA ACCGTCTTGG GAAATCACCC


 


101
TGATTGAACG CTTGGAagat gTGGCGTTGG AATCGTCAAA cGCGTGGAAC


 


151
AACGcCGgca CGGGGCATTC CGcGCTGTGc GAATTGAACT AtgcgccGCT


 


201
GGGtgcggac ggcgtcatCA ATCCGGCGCg cgCCCTGAAT ATTGCCGAAC


 


251
AGTTTCATGT CAGCCGCCAG TTTTGGGcga cgctggTCGC GGAAGGCAAG


 


301
TTGGAAGACA ATTCCTTCAT CAATGCCGTG CCGCATATGT CTTTGGTGAT


 


351
GAACGAAGAC CACTGCCGTT ACCTGCAAAA ACGCTATGAT GTGTTTAAAA


 


401
CGCAGAAACT TTTTGAAAAT ATGGAATTTT CCACCGATCG GAACAAAATT


 


451
TCCGATTGGG CtccgCTGAT TATGCGCGGC CGGGACGAAA ACCAACCCGT


 


501
CGCCGCCAAC TATTCCGCCG AAGGCACGGA TGTCGATTTC GGACGGCTGA


 


551
CGCGCCAGAT GGTGAAATAT TTGCAGGGCA AGGGCGTAAA AACCGAGTTC


 


601
AACCGCCACG TCGAAGACAT CAAACGCGAA TCCGACGGCG CGTGGGTGCT


 


651
CAAAACCGCC GATACCCGCA ACCCAGACTG GCAGCTCACC CTCCGCACCC


 


701
GCTTCCTCTT CCTCGGCGCG GGCGGCGGCG CACTGACCCT GCTGCAAAAA


 


751
TCCGGCATCC CCGAAGGCAA AGGCTACGGC GGCTTACCCG TGTCCGGCCT


 


801
GTTCTTCCGC AACAGCAACC CCGAAACCGC CGAACAACAC AACGCCAAAG


 


851
TGTACGGGCA GGCTTCCGTC GGCGCGCCGC CGATGTCCGT CCCGCACCTC


 


901
GACACACGCA ACGTAGACGG CAAACGACAC CTTATGTTCG GTCCTTACGC


 


951
AGGTTTCCGT TCCAACTTCC TCAAGCAAGG CTCGTTTATG GATTTGCCGC


 


1001
TGTCCATCCA TATGGACAAC CTCTATCCTA TGCTGCGCGC CGGCTGGGCG


 


1051
AATATGCCGC TGACCAAATA CCTGCTGGGC GAATTGCGTA AAACCAAAGA


 


1101
AGAACGCTtt gCCTCCCTGC TGgaatacta cccGaggcag acccGACGAc


 


1151
tggtactcat cacgcaggnc acGCGTcata tcattanata tgactCgaaa


 


1201
ctgcgcgtgc tgcagttgta cgagattgtg ccaCGCGacg ctcgctcgcg


 


1251
cattctggag cgtcgcggcg catcacgctn tgcgctgata tccgctgatg


 


1301
acactgctcc gaGCGcgccc gtcttggaaa gtgtctga






This corresponds to the amino acid sequence <SEQ ID 692; ORF 165-1.ng>:










g165-1.pep




1
MAEATDVVLV GGGIMSATLG VLLKELEPSW EITLIERLED VALESSNAWN


 


51
NAGTGHSALC ELNYAPLGAD GVINPARALN IAEQFHVSRQ FWATLVAEGK


 


101
LEDNSFINAV PHMSLVMNED HCRYLQKRYD VFKTQKLFEN MEFSTDRNKI


 


151
SDWAPLIMRG RDENQPVAAN YSAEGTDVDF GRLTRQMVKY LQGKGVKTEF


 


201
NRHVEDIKRE SDGAWVLKTA DTRNPDWQLT LRTRFLFLGA GGGALTLLQK


 


251
SGIPEGKGYG GLPVSGLFFR NSNPETAEQH NAKVYGQASV GAPPMSVPHL


 


301
DTRNVDGKRH LMFGPYAGFR SNFLKQGSFM DLPLSIHMDN LYPMLRAGWA


 


351
NMPLTKYLLG ELRKTKEERF ASLLEYYPRQ TRRLVLITQX TRHIIXYDSK


 


401
LRVLQLYEIV PRDARSRILE RRGASRXALI SADDTAPSAP VLESV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 693>:










m165-1.seq




1
ATGGCTGAAG CGACAGACGT TGTCTTGGTG GGCGGCGGCA TTATGAGCGC


 


51
GACTTTGGGC GTTTTGCTCA AAGAACTCGA ACCGTCTTGG GAAATCACCC


 


101
TGATTGAACG CTTGGAAGAT GTGGCGTTGG AATCGTCAAA CGCGTGGAAC


 


151
AACGCCGGCA CGGGGCATTC CGCGCTGTGC GAATTGAACT ATGCGCCGTT


 


201
GGGTGCAAAT GGGATTATCG ATCCGGCGCG CGCCCTCAAT ATTGCCGAAC


 


251
AGTTTCATGT CAGCCGCCAG TTTTGGGCGA CGCTGGTCGC GGAAGGCAAG


 


301
TTGGAAGACA ATTCCTTCAT CAATGCCGTG CCGCATATGT CTTTGGTGAT


 


351
GAATGAAGAC CATTGTTCTT ATCTTCAAAA ACGTTATGAC GCGTTTAAAA


 


401
CCCAAAAACT TTTTGAAAAT ATGGAATTTT CCACCGATCG GAACAAAATT


 


451
TCCGATTGGG CTCCGCTGAT GATGCGCGGC CGGGACGAAA ACCAACCCGT


 


501
CGCCGCCAAC TACTCCGCCG AAGGTACGGA TGTCGATTTC GGACGGCTGA


 


551
CGCGCCAAAT GGTGAAATAT TTGCAGGGCA AGGGCGTAAA AACCGAGTTC


 


601
AACCGCCACG TCGAAGACAT CAAACGCGAA TCCGACGGCG CGTGGGTGCT


 


651
CAAAACCGCC GATACCCGCA ACCCCGACGG GCAGCTCACC CTCCGTACCC


 


701
GCTTCCTCTT CCTCGGCGCG GGCGGCGGCG CGCTGACCCT GCTGCAAAAA


 


751
TCCGGCATCC CCGAAGGCAA AGGCTACGGC GGCTTCCCCG TGTCCGGCCT


 


801
GTTCTTCCGC AACAGCAACC CCGAAACCGC CGAACAACAC AACGCCAAAG


 


851
TGTACGGGCA GGCTTCCGTC GGCGCGCCGC CGATGTCCGT CCCGCACCTC


 


901
GACACACGCA ACGTGGACGG CAAACGCCAC CTTATGTTCG GCCCTTACGC


 


951
AGGCTTCCGT TCCAACTTCC TCAAGCAAGG CTCGCTTATG GATTTGCCGC


 


1001
TGTCCATCCA TATGGACAAC CTCTATCCTA TGCTGTGCGC CGGCTGGGCG


 


1051
AATATGCCGC TGACCAAATA CCTGCTGGGC GAATTGCGTA AAACCAAAGA


 


1101
AGAACGCTTC GCCTCCCTGC TGGAATACTA CCCCGAGGCA AACCCCGACG


 


1151
ACTGGGAACT CATCACCGCA GGGCAACGCG TCCAAATCAT TAAAAAAGAC


 


1201
TCCGAAAAAG GCGGCGTGCT CCAGTTTGGT ACGGAGATTG TCGCCCACGC


 


1251
CGACGGCTCA CTCGCCGCAT TGCTGGGCGC GTCGCCGGGC GCATCGACCG


 


1301
CTGTGCCGCT GATGATCCGG CTGATGCACC AATGCTTCCC CGAGCGCGCC


 


1351
CCGTCTTGGG AAGACCGTCT GAAAGAGCTG GTACCGGGTT ACGGCATCAA


 


1401
GTTGAACGAA AACCCTGAAA GGGCGGATGA AATTATCGCC TATACCGCGA


 


1451
AAGTATTGGA TATTTAA






This corresponds to the amino acid sequence <SEQ ID 694; ORF 165-1>:










m165-1.pep




1
MAEATDVVLV GGGIMSATLG VLLKELEPSW EITLIERLED VALESSNAWN


 


51
NAGTGHSALC ELNYAPLGAN GIIDPARALN IAEQFHVSRQ FWATLVAEGK


 


101
LEDNSFINAV PHMSLVMNED HCSYLQKRYD AFKTQKLFEN MEFSTDRNKI


 


151
SDWAPLMMRG RDENQPVAAN YSAEGTDVDF GRLTRQMVKY LQGKGVKTEF


 


201
NRHVEDIKRE SDGAWVLKTA DTRNPDGQLT LRTRFLFLGA GGGALTLLQK


 


251
SGIPEGKGYG GFPVSGLFFR NSNPETAEQH NAKVYGQASV GAPPMSVPHL


 


301
DTRNVDGKRH LMFGPYAGFR SNFLKQGSLM DLPLSIHMDN LYPMLCAGWA


 


351
NMPLTKYLLG ELRKTKEERF ASLLEYYPEA NPDDWELITA GQRVQIIKKD


 


401
SEKGGVLQFG TEIVAHADGS LAALLGASPG ASTAVPLMIR LMHQCFPERA


 


451
PSWEDRLKEL VPGYGIKLNE NPERADEIIA YTAKVLDI*






m165-1/g165-1 89.7% identity in 428 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 695>:










a165-1.seq




1
ATGGCTGAAG CGACAGACGT TGTCTTGGTG GGCGGCGGCA TTATGAGCGC


 


51
GACTTTGGGC GTTTTGCTCA AAGAACTCGA ACCGTCTTGG GAAATCACCC


 


101
TGATTGAACG CTTGGAAGAT GTGGCGTTGG AATCGTCAAA CGCGTGGAAC


 


151
AACGCCGGCA CGGGGCATTC CGCGCTGTGC GAATTGAACT ATGCGCCGTT


 


201
GGGTGCAAAT GGGATTATCG ATCCGGCGCG CGCCCTCAAT ATTGCCGAAC


 


251
AGTTTCATGT CAGCCGCCAG TTTTGGGCGA CGTTGGTCGC GGAAGGCAAG


 


301
TTGGAAGACA ATTCCTTCAT CAATGCCGTG CCGCATATGT CTTTGGTGAT


 


351
GAATGAAGAC CATTGTTCTT ATCTTCAAAA ACGTTATGAC GCGTTTAAAA


 


401
CCCAAAAACT TTTTGAAAAT ATGGAATTTT CCACCGATCG GAACAAAATT


 


451
TCCGATTGGG CTCCGCTGAT GATGCGCGGC CGGGACGAAA ACCAACCCGT


 


501
CGCCGCCAAC TACTCCGCCG AAGGCACGGA TGTCGATTTC GGACGGCTGA


 


551
CGCGCCAAAT GGTGAAATAT TTGCAGGGCA AGGGCGTAAA AACCGAGTTC


 


601
AACCGCCACG TCGAAGACAT CAAACGCGAA TCCGACGGCG CGTGGGTGCT


 


651
CAAAACCGCC GATACCCGCA ACCCCGACGG GCAGCTCACC CTCCGTACCC


 


701
GCTTCCTCTT CCTCGGCGCG GGCGGCGGCG CGCTGACCCT GCTGCAAAAA


 


751
TCCGGCATCC CCGAAGGCAA AGGCTACGGT GGCTTTCCCG TGTCCGGCCT


 


801
GTTCTTCCGC AACAGCAACC CCGAAACCGC CGAACAACAC AACGCCAAAG


 


851
TGTACGGGCA GGCTTCCGTC GGCGCGCCGC CGATGTCCGT CCCGCACCTC


 


901
GACACACGCA ACGTGGACGG CAAACGCCAC CTTATGTTCG GCCCTTACGC


 


951
AGGCTTCCGT TCCAACTTCC TCAAGCAAGG CTCACTTATG GATTTGCCGC


 


1001
TGTCCATCCA TATGGACAAC CTCTATCCTA TGCTGCGCGC CGGCTGGGCG


 


1051
AATATGCCGC TGACCAAATA CCTGCTGGGC GAATTGCGTA AAACCAAAGA


 


1101
AGAACGCTTC GCCTCCCTGC TGGAATACTA CCCCGAGGCA AACCCCGACG


 


1151
ACTGGGAACT CATCACCGCA GGGCAACGCG TTCAAATCAT TAAAAAAGAC


 


1201
TCCGAAAAAG GCGGCGTGTT GCAGTTTGGT ACGGAGATTG TCGCACACGC


 


1251
CGACGGCTCG CTCGCCGCAT TGCTGGGCGC GTCGCCGGGC GCATCGACCG


 


1301
CCGTGCCGCT GATGATCCGG CTGATGCACC AATGCTTCCC CGAACGCACC


 


1351
CCGTCTTGGG AAGGCCGTCT GAAAGAGCTG GTACCGGGTT ACGGCATCAA


 


1401
GTTGAACGAA AACCCCGAAA GGGCGGATGA AATTATCGCC TATACCGCGA


 


1451
AAGTGTTGGA TATTTAA






This corresponds to the amino acid sequence <SEQ ID 696; ORF 165-1.a>:










a165-1.pep




1
MAEATDVVLV GGGIMSATLG VLLKELEPSW EITLIERLED VALESSNAWN


 


51
NAGTGHSALC ELNYAPLGAN GIIDPARALN IAEQFHVSRQ FWATLVAEGK


 


101
LEDNSFINAV PHMSLVMNED HCSYLQKRYD AFKTQKLFEN MEFSTDRNKI


 


151
SDWAPLMMRG RDENQPVAAN YSAEGTDVDF GRLTRQMVKY LQGKGVKTEF


 


201
NRHVEDIKRE SDGAWVLKTA DTRNPDGQLT LRTRFLFLGA GGGALTLLQK


 


251
SGIPEGKGYG GFPVSGLFFR NSNPETAEQH NAKVYGQASV GAPPMSVPHL


 


301
DTRNVDGKRH LMFGPYAGFR SNFLKQGSLM DLPLSIHMDN LYPMLRAGWA


 


351
NMPLTKYLLG ELRKTKEERF ASLLEYYPEA NPDDWELITA GQRVQIIKKD


 


401
SEKGGVLQFG TEIVAHADGS LAALLGASPG ASTAVPLMIR LMHQCFPERT


 


451
PSWEGRLKEL VPGYGIKLNE NPERADEIIA YTAKVLDI*






a165-1/m165-1 99.4% identity in 488 aa overlap





a165-1/p33940









sp|P33940|YOJH–ECOLI HYPOTHETICAL 60.2 KD PROTEIN IN ECO-ALKB INTERGENIC



REGION >gi|1736851|gnl|PID|d1016718 (D90850) ORF_ID: o372#5; similar


to [SwissProt Accession Number P33940] [Escherichia coli] >gi|1788539


(AE000310) f548; This 548 aa ORF is 100 pct identical to 490 residues


of YOJH_ECOLI SW: P33940 (492 aa) but contains 56 additional N-ter aa;


100 pct identical to GB: ECOHU49_33


ACCESSION: U00008 (490 aa) but contains 58 aditional N-term resi... 


Length = 548 Score = 458 bits (1167), Expect = e−128


Identities = 233/490 (47%), Positives = 303/490 (61%), Gaps = 5/490 (1%)











Query:
3
EATDVVLVGGGIMSATLGVLLKELEPSWEITLIERLEDVALESSNAWNNAGTGHSALCEL
62





+ TDV+L+GGGIMSATLG  L+ELEP W +T++ERLE VA ESSN WNNAGTGHSAL EL


Sbjct:
30
QETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMEL
89


 


Query:
63
NYAPLGANGIIDPARALNIAEQFHVSRQFWATLVAEGKLED-NSFINAVPHMSLVMNEDH
121




NY P  A+G I   +A+ I E F +SRQFWA  V  G L    SFIN VPHMS V  ED+


Sbjct:
90
NYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDN
149


 


Query:
122
CSYLQKRYDAFKTQKLFENMEFSTDRNKISDWAPLMMRGRDENQPVAANYSAEGTDVDFG
181




++L+ RY A +   LF  M +S D  +I +WAPL+M GRD  Q VAA  +  GTDV++G


Sbjct:
150
VNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYG
209


 


Query:
182
RLTRQMVKYLQGKG-VKTEFNRHVEDIKRESDGAWVLKTADTRNPDGQLTXXXXXXXXXX
240




 +TRQ++  LQ K     + +  V  +KR  D  W +  AD +N   Q


Sbjct:
210
EITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQ-NIRAKFVFIGA
268


 


Query:
241
XXXXXXXXQKSGIPEGKGYGGFPVSGLFFRNSNPETAEQHNAKVYGQASVGAPPMSVPHL
300




        Q+SGIPE K Y GFPV G F  + NP+    H AKVYG+ASVGAPPMSVPH+


Sbjct:
269
GGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHI
328


 


Query:
301
DTRNVDGKRHLMFGPYAGFRSNFLKQGSLMDLPLSIHMDNLYPMLRAGWANMPLTKYLLG
360




DTR +DGKR ++FGP+A F +FLK GSL DL  S    N+ PM+  G  N  L KYL+


Sbjct:
329
DTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVS
388


 


Query:
361
ELRKTKEERFASLLEYYPEANPDDWELITAGQRVQIIKKDSEKGGVLQFGTEIVXXXXXX
420




++  ++E+RF +L EYYP+A  +DW L  AGQRVQIIK+D+EKGGVL+GTE+V


Sbjct:
389
QVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGT
448


 


Query:
421
XXXXXXXXXXXXXXVPLMIRLMHQCFPER--TPSWEGRLKELVPGYGIKLNENPERADEI
478




               P+M+ L+ + F +R  +P W+  LK +VP YG KLN +    +


Sbjct:
449
IAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
508


 


Query:
479
IAYTAKVLDI
488




+ YT++VL +


Sbjct:
509
LQYTSEVLGL
518






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 697>:










g204.seq




1
atggcggcgg cggaaataaa acgccccctc gctgtcgatt tccagcacat


 


51
agcgtccgtt ctgcacggcg gcatagccgc ttttgcctgc ctgatagggt


 


101
tgcagggcgg aatgcgaaat caggtaatca gtcagtttgc cgccgtcttc


 


151
ggcgatattg cccaccagtt tggcaaacaa ggtatggcac acgccgtttt


 


201
ccgcccagcc cgaaggcgcg tcctttccgt cggtttccat acatttgccg


 


251
acgacggctt ccaagtcgtt gggatgcttt ccggtcagcc ggacggcgtt


 


301
ttgttccggc aagcctttaa tcggataact gatttgtttt ttgccgtcgt


 


351
tggttttgcc ttcgctactt tgtcccaaag ccaaaccggc aatcgccgta


 


401
ttgtcgatgt atttgacttt gaaaaccggt ttcggcgcgc tttgtgccgc


 


451
attttgcggc tgttccgccg tattttcgga tttgccgcag gcggcaagca


 


501
gcaggcagcc gcccaacacg gcaaaaggta ttttcagcat tccgcactcc


 


551
tgatggtttc aaaatgccgt ctgaaatgcc gtctgaaacg tggcaggcgg


 


601
aggttcggac ggcattgggt ttatttcaac gggcggatgc cgaccgcatc


 


651
gcgtacttta tccaacaatt cgcgcgcttc tttgcgcgct ttttgcgcgc


 


701
ctgcctgcaa aatctcttcg atttgcgaag gattagaggt caatgcgttg


 


751
tag






This corresponds to the amino acid sequence <SEQ ID 698; ORF 204.ng>:










g204.pep




1
MAAAEIKRPL AVDFQHIASV LHGGIAAFAC LIGLQGGMRN QVISQFAAVF


 


51
GDIAHQFGKQ GMAHAVFRPA RRRVLSVGFH TFADDGFQVV GMLSGQPDGV


 


101
LFRQAFNRIT DLFFAVVGFA FATLSQSQTG NRRIVDVFDF ENRFRRALCR


 


151
ILRLFRRIFG FAAGGKQQAA AQHGKRYFQH SALLMVSKCR LKCRLKRGRR


 


201
RFGRHWVYFN GRMPTASRTL SNNSRASLRA FCAPACKISS ICEGLEVNAL


 


251
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 699>:










m204.seq




1
ATGGCGGCGG CGGAAATAAA ACGCCCCTTC GCTGTCGATT TCCAGCACAT


 


51
AGCGTCCGTT CTGCACGGCG GCATAGCCGC TTTTGCCTGC CTGATAGGGT


 


101
TGCAGGGCGG CATGCGAAAC TAGGTAATCC GTCAGTTTGC CGCCGTCTTC


 


151
GGCGATATTG CCCACCAGTT TGGCAAACAA GGTATGGCAC ACGCCGTTTT


 


201
CTGCCCAACC TGCCGGACTG TCCTTATCAT CGGTTTCCAT ACATTTGCCG


 


251
CTGACGGCTT CCAAGTCGCC GGGATGCTTG CCGATCAGTC GGATAACATT


 


301
TTGTTCCGGC AAGCCTTTAA TCGGATAACT GATTTGTTTT TTGCCGTCGT


 


351
TGGTTTTGCC TTCGCTGCTT TGTCCCAAAT CCAAACCGGC AATCGCCGTA


 


401
TTGTCGATAT ATATGACTTT GAAAACCGGT TTCGGCGCGC TTTGTACCGC


 


451
GTTTTGCGGC TGTACCGCCG TATTTwCGGA TTTGCCGCaC GGCaArGCAG


 


501
CAGGCAGCCG CCCAATACGG CAAAArAwGT wTTCAGCATT CCACAyTCCT


 


551
GATGGTTTCA AAATGCCGTC TGAAACGCGG CAGGCGGAGG TTCGGACGGC


 


601
ATCGGGTTCA TTTCAACGGG CGGATGcCGA CCGCATCgGT ACTTTGTCCA


 


651
ATAATTCGCG TGCTTCTTTA CGCGCTTTCG CCGCGCCTGC CTGCAAAATC


 


701
TCTTCGATTT GCGAAGGGTC GGCGGTCAGC TCGTTGTAG






This corresponds to the amino acid sequence <SEQ ID 700; ORF 204>:










m204.pep




1
MAAAEIKRPF AVDFQHIASV LHGGIAAFAC LIGLQGGMRN *VIRQFAAVF


 


51
GDIAHQFGKQ GMAHAVFCPT CRTVLIIGFH TFAADGFQVA GMLADQSDNI


 


101
LFRQAFNRIT DLFFAVVGFA FAALSQIQTG NRRIVDIYDF ENRFRRALYR


 


151
VLRLYRRIXG FAATAXQQAA AQYGKXXXQH STXLMVSKCR LKRGRRRFGR


 


201
HRVHFNGRMP TASGTLSNNS RASLRAFAAP ACKISSICEG SAVSSL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 204 shows 82.0% identity over a 250 aa overlap with a predicted ORF (ORF 204.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 701>:










a204.seq




1
ATGGCGGCGG CGGAAATAAA ACGCCCCCTC GCTGTCGATT TCCAGCACAT


 


51
AGCGTCCGTT CTGCACGGCG GCATAGCCGC TTTTGCCTGC CTGATAGGGT


 


101
TGCAGGGCGG AATGCGAAAT CAGGTAATCC GTCAGTTTGC CGCCGTCTTC


 


151
GGCGATATTG CCCACCAGTT TGGCAAACAA GGTATGGCAC ACGCCGTTTG


 


201
CCGCCCAGCC CGAAGGCGCG CCCTTTCCGT CGGTTTCCAT ACATTTGCCG


 


251
ACGACGGCTT CCAAGTCGTT GGGATGCTTG CCGGTCAGCC GGACGACGTT


 


301
TTGTTCCGGC AAGCCTTT.. .......... .......... ..........


351
.......... .......... .......... .......... ..........


401
.......... .......... .......... .......... ..........


451
.......... .......... .......... .......... ..........


501
.......... .......... .......... .......... ..........


551
.......... .......... .......... .....AAGAG GTTCGGACGG


 


601
CATTGGGTTT ATTTCAACGG GCGGATACCG ACCGCATCAC GTACTTTGCC


 


651
CAATAATTCG CGTGCTTCTT TACGCGCTTT TTGCGCGCCT GCCTGCAAAA


 


701
TCTCTTCGAT TTGCGAAGGG TCGGCGGTCA GCTCGTTGTA G






This corresponds to the amino acid sequence <SEQ ID 702; ORF 204.a>:










a204.pep




1
MAAAEIKRPL AVDFQHIASV LHGGIAAFAC LIGLQGGMRN QVIRQFAAVF


 


51
GDIAHQFGKQ GMAHAVCRPA RRRALSVGFH TFADDGFQVV GMLAGQPDDV


 


101
LFRQAF.... .......... .......... .......... ..........


151
.......... .......... .......... .......... .....KRFGR


 


201
HWVYFNGRIP TASRTLPNNS RASLRAFCAP ACKISSICEG SAVSSL*






m204/a204 54.5% identity in 246 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 703>:










g205.seq




1
atgctgaaaa taccttttgc cgtgttgggc ggctgcctgc tgcttgccgc


 


51
ctgcggcaaa tccgaaaata cggcggaaca gccgcaaaat gcggcacaaa


 


101
gcgcgccgaa accggttttc aaagtcaaat acatcgacaa tacggcgatt


 


151
gccggtttgg ctttgggaca aagtagcgaa ggcaaaacca acgacggcaa


 


201
aaaacaaatc agttatccga ttaaaggctt gccggaacaa aacgccgtcc


 


251
ggctgaccgg aaagcatccc aacgacttgg aagccgtcgt cggcaaatgt


 


301
atggaaaccg acggaaagga cgcgccttcg ggctgggcgg aaaacggcgt


 


351
gtgccatacc ttgtttgcca aactggtggg caatatcgcc gaagacggcg


 


401
gcaaactgac tgattacctg atttcgcatt ccgccctgca accctatcag


 


451
gcaggcaaaa gcggctatgc cgccgtgcag aacggacgct atgtgctgga


 


501
aatcgacagc gagggggcgt tttatttccg ccgccgccat tattga






This corresponds to the amino acid sequence <SEQ ID 704; ORF 205.ng>:










g205.pep




1
MLKIPFAVLG GCLLLAACGK SENTAEQPQN AAQSAPKPVF KVKYIDNTAI


 


51
AGLALGQSSE GKTNDGKKQI SYPIKGLPEQ NAVRLTGKHP NDLEAVVGKC


 


101
METDGKDAPS GWAENGVCHT LFAKLVGNIA EDGGKLTDYL ISHSALQPYQ


 


151
AGKSGYAAVQ NGRYVLEIDS EGAFYFRRRH Y






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 705>:










m205.seq




1
ATGCTGAAwA CwTyTTTTGC CGTATTGGGC GGCTGCCTGC TGCyTtGCCG


 


51
tGCGGCAAAT CCGwAAATAC GGCGGTACAG CCGCAAAACG CGGTACAAAG


 


101
CGCGCCGAAA CCGGTTTTCA AAGTCATATA TATCGACAAT ACGGCGATTG


 


151
CCGGTTTGGA TTTGGGACAA AGCAGCGAAG GCAAAACCAA CGACGGCAAA


 


201
AAACAAATCA GTTATCCGAT TAAAGGCTTG CCGGAACAAA ATGTTATCCG


 


251
ACTGATCGGC AAGCATCCCG GCGACTTGGA AGCCGTCAGC GGCAAATGTA


 


301
TGGAAACCGA TGATAAGGAC AGTCCGGCAG GTTGGGCAGA AAACGGCGTG


 


351
TGCCATACCT TGTTTGCCAA ACTGGTGGGC AATATCGCCG AAGACGGCGG


 


401
CAAACTGACG GATTACCTAG TTTCGCATGC CGCCCTGCAA CCCTATCAGG


 


451
CAGGCAAAAG CGGCTATGCC GCCGTGCAGA ACGGACGCTA TGTGCTGGAA


 


501
ATCGACAGCG AAGGGGCGTT TTATTTCCGC CGCCGCCATT ATTGA






This corresponds to the amino acid sequence <SEQ ID 706; ORF 205>:










m205.pep




1
MLXTXFAVLG GCLLXCRCGK SXNTAVQPQN AVQSAPKPVF KVIYIDNTAI


 


51
AGLDLGQSSE GKTNDGKKQI SYPIKGLPEQ NVIRLIGKHP GDLEAVSGKC


 


101
METDDKDSPA GWAENGVCHT LFAKLVGNIA EDGGKLTDYL VSHAALQPYQ


 


151
AGKSGYAAVQ NGRYVLEIDS EGAFYFRRRH Y*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 205 shows 88.4% identity over a 181 aa overlap with a predicted ORF (ORF 205.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 707>:










a205.seq (partial)











1
TCCGAACCTC TTAAAGGCTT GCCGGAACAA AACGTCGTCC GGCTGACCGG



 


51
CAAGCATCCC AACGACTTGG AAGCCGTCGT CGGCAAATGT ATGGAAACCG


 


101
ACGGAAAGGG CGCGCCTTCG GGCTGGGCGG CAAACGGCGT GTGCCATACC


 


151
TTGTTTGCCA AACTGGTGGG CAATATCGCC GAAGACGGCG GCAAACTGAC


 


201
GGATTACCTG ATTTCGCATT CCGCCCTGCA ACCCTATCAG GCAGGCAAAA


 


251
GCGGCTATGC CGCCGTGCAG AACGGACGCT ATGTGCTGGA AATCGACAGC


 


301
GAGGGGGCGT TTTATTTCCG CCGCCGCCAT TATTGA






This corresponds to the amino acid sequence <SEQ ID 708; ORF 205.a>:










a205.pep (partial)










1
SEPLKGLPEQ NVVRLTGKHP NDLEAVVGKC METDGKGAPS GWAANGVCHT


 


51
LFAKLVGNIA EDGGKLTDYL ISHSALQPYQ AGKSGYAAVQ NGRYVLEIDS


 


101
EGAFYFRRRH Y*






m205/a205 88.3% identity in 111 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 709>:










g205-1.seq (partial)











1
ATGCTGAAAA TAcCTTTTGC CGTGTTGGGC GGCTGCCTGC TGCTTGCCGC



 


51
CTGCGGCAAA TCCGAAAATA CGGCGGAACA GCCGCAAAAT GCGGCACAAA


 


101
GCGCGCCGAA ACCGGTTTTC AAAGTCAAAT ACATCGACAA TACGGCGATT


 


151
GCCGGTTTGG CTTTGGGACA AAGTAGCGAA GGCAAAACCA ACGACGGCAA


 


201
AAAACAAATC AGTTATCCGA TTAAAGGCTT GCCGGAACAA AACGCCGTCC


 


251
GGCTGACCGG AAAGCATCCC AACGACTTGG AAGCCGTCGT CGGCAAATGT


 


301
ATGGAAACCG ACGGAAAGGA CGCGCCTTCG GGCTGGGCGG AAAACGGCGT


 


351
GTGCCATACC TTGTTTGCCA AACTGGTGGG CAATATCGCC GAAGACGGCG


 


401
GCAAACTGAC TGATTACCTG ATTTCGCATT CCGCCCTGCA ACCCTATCAG


 


451
GCAGGCAAAA GCGGCTATGC CGCCGTGCAG AACGGACGCT ATGTGCTGGA


 


501
AATCGACAGC GAGGGGGCGT TTTA






This corresponds to the amino acid sequence <SEQ ID 710; ORF 205-1.ng>:










g205-1.pep (partial).











1
MLKIPFAVLG GCLLLAACGK SENTAEQPQN AAQSAPKPVF KVKYIDNTAI



 


51
AGLALGQSSE GKTNDGKKQI SYPIKGLPEQ NAVRLTGKHP NDLEAVVGKC


 


101
METDGKDAPS GWAENGVCHT LFAKLVGNIA EDGGKLTDYL ISHSALQPYQ


 


151
AGKSGYAAVQ NGRYVLEIDS EGAF






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 711>:










m205-1.seq..




1
ATGCTGAAAA CATCTTTTGC CGTATTGGGC GGCTGCCTGC TGCTTGCCGC


 


51
CTGCGGCAAA TCCGAAAATA CGGCGGAACA GCCGCAAAAC GCGGTACAAA


 


101
GCGCGCCGAA ACCGGTTTTC AAAGTCAAAT ATATCGACAA TACGGCGATT


 


151
GCCGGTTTGG ATTTGGGACA AAGCAGCGAA GGCAAAACCA ACGACGGCAA


 


201
AAAACAAATC AGTTATCCGA TTAAAGGCTT GCCGGAACAA AATGTTATCC


 


251
GACTGATCGG CAAGCATCCC GGCGACTTGG AAGCCGTCAG CGGCAAATGT


 


301
ATGGAAACCG ATGATAAGGA CAGTCCGGCA GGTTGGGCAG AAAACGGCGT


 


351
GTGCCATACC TTGTTTGCCA AACTGGTGGG CAATATCGCC GAAGACGGCG


 


401
GCAAACTGAC GGATTACCTA GTTTCGCATG CCGCCCTGCA ACCCTATCAG


 


451
GCAGGCAAAA GCGGCTATGC CGCCGTGCAG AACGGACGCT ATGTGCTGGA


 


501
AATCGACAGC GAAGGGGCGT TTTATTTCCG CCGCCGCCAT TATTGA






This corresponds to the amino acid sequence <SEQ ID 712; ORF 205-1>:










m205-1.pep




1
MLKTSFAVLG GCLLLAACGK SENTAEQPQN AVQSAPKPVF KVKYIDNTAI


 


51
AGLDLGQSSE GKTNDGKKQI SYPIKGLPEQ NVIRLIGKHP GDLEAVSGKC


 


101
METDDKDSPA GWAENGVCHT LFAKLVGNIA EDGGKLTDYL VSHAALQPYQ


 


151
AGKSGYAAVQ NGRYVLEIDS EGAFYFRRRH Y*






m205-1/g205-1 92.0% identity in 174 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 713>:










a205-1.seq (partial)











1
CCTCTTAAAG GCTTGCCGGA ACAAAACGTC GTCCGGCTGA CCGGCAAGCA



 


51
TCCCAACGAC TTGGAAGCCG TCGTCGGCAA ATGTATGGAA ACCGACGGAA


 


101
AGGGCGCGCC TTCGGGCTGG GCGGCAAACG GCGTGTGCCA TACCTTGTTT


 


151
GCCAAACTGG TGGGCAATAT CGCCGAAGAC GGCGGCAAAC TGACGGATTA


 


201
CCTGATTTCG CATTCCGCCC TGCAACCCTA TCAGGCAGGC AAAAGCGGCT


 


251
ATGCCGCCGT GCAGAACGGA CGCTATGTGC TGGAAATCGA CAGCGAGGGG


 


301
GCGTTTTATT TCCGCCGCCG CCATTATTGA






This corresponds to the amino acid sequence <SEQ ID 714; ORF 205-1.a>:










a205-1.pep (partial)











1
PLKGLPEQNV VRLTGKHPND LEAVVGKCME TDGKGAPSGW AANGVCHTLF



 


51
AKLVGNIAED GGKLTDYLIS HSALQPYQAG KSGYAAVQNG RYVLEIDSEG


 


101
AFYFRRRHY*






m205-1/a205-1 89.0% identity in 109 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 715>:










g206.seq




1
atgttttccc ccgacaaaac ccttttcctc tgtctcggcg cactgctcct


 


51
cgcctcatgc ggcacgacct ccggcaaaca ccgccaaccg aaacccaaac


 


101
agacagtccg gcaaatccaa gccgtccgca tcagccacat cggccgcaca


 


151
caaggctcgc aggaactcat gctccacagc ctcggactca tcggcacgcc


 


201
ctacaaatgg ggcggcagca gcaccgcaac cggcttcgac tgcagcggca


 


251
tgattcaatt ggtttacaaa aacgccctca acgtcaagct gccgcgcacc


 


301
gcccgcgaca tggcggcggc aagccgcaaa atccccgaca gccgcctcaa


 


351
ggccggcgac atcgtattct tcaacaccgg cggcgcacac cgctactcac


 


401
acgtcggact ctacatcggc aacggcgaat tcatccatgc ccccggcagc


 


451
ggcaaaacca tcaaaaccga aaaactctcc acaccgtttt acgccaaaaa


 


501
ctaccttgga gcgcatacgt tttttacaga atga






This corresponds to the amino acid sequence <SEQ ID 716; ORF 206.ng>:










g206.pep




1
MFSPDKTLFL CLGALLLASC GTTSGKHRQP KPKQTVRQIQ AVRISHIGRT


 


51
QGSQELMLHS LGLIGTPYKW GGSSTATGFD CSGMIQLVYK NALNVKLPRT


 


101
ARDMAAASRK IPDSRLKAGD IVFFNTGGAH RYSHVGLYIG NGEFIHAPGS


 


151
GKTIKTEKLS TPFYAKNYLG AHTFFTE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 717>:










m206.seq




1
ATGTTTCCCC CCGACAAAAC CCTTTTCCTC TGTCTCAGCG CACTGCTCCT


 


51
CGCCTCATGC GGCACGACCT CCGGCAAACA CCGCCAACCG AAACCCAAAC


 


101
AGACAGTCCG GCAAATCCAA GCCGTCCGCA TCAGCCACAT CGACCGCACA


 


151
CAAGGCTCGC AGGAACTCAT GCTCCACAGC CTCGGACTCA TCGGCACGCC


 


201
CTACAAATGG GGCGGCAGCA GCACCGCAAC CGGCTTCGAT TGCAGCGGCA


 


251
TGATTCAATT CGTTTACAAr AACGCCCTCA ACGTCAAGCT GCCGCGCACC


 


301
GCCCGCGACA TGGCGGCGGC AAGCCGsAAA ATCCCCGAcA GCCGCyTCAA


 


351
GGCCGGCGAC CTCGTATTCT TCAACACCGG CGGCGCACAC CGCTACTCAC


 


401
ACGTCGGACT CTACATCGGC AACGGCGAAT TCATCCATGC CCCCAGCAGC


 


451
GGCAAAACCA TCAAAACCGA AAAACTCTCC ACACCGTTTT ACGCCAAAAA


 


501
CTACCTCGGC GCACATACTT TTTTTACAGA ATGA






This corresponds to the amino acid sequence <SEQ ID 718; ORF 206>:










m206.pep..




1
MFPPDKTLFL CLSALLLASC GTTSGKHRQP KPKQTVRQIQ AVRISHIDRT


 


51
QGSQELMLHS LGLIGTPYKW GGSSTATGFD CSGMIQFVYK NALNVKLPRT


 


101
ARDMAAASRK IPDSRXKAGD LVFFNTGGAH RYSHVGLYIG NGEFIHAPSS


 


151
GKTIKTEKLS TPFYAKNYLG AHTFFTE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 206 shows 96.0% identity over a 177 aa overlap with a predicted ORF (ORF 206.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 719>:










a206.seq




1
ATGTTTCCCC CCGACAAAAC CCTTTTCCTC TGTCTCAGCG CACTGCTCCT


 


51
CGCCTCATGC GGCACGACCT CCGGCAAACA CCGCCAACCG AAACCCAAAC


 


101
AGACAGTCCG GCAAATCCAA GCCGTCCGCA TCAGCCACAT CGACCGCACA


 


151
CAAGGCTCGC AGGAACTCAT GCTCCACAGC CTCGGACTCA TCGGCACGCC


 


201
CTACAAATGG GGCGGCAGCA GCACCGCAAC CGGCTTCGAT TGCAGCGGCA


 


251
TGATTCAATT CGTTTACAAA AACGCCCTCA ACGTCAAGCT GCCGCGCACC


 


301
GCCCGCGACA TGGCGGCGGC AAGCCGCAAA ATCCCCGACA GCCGCCTTAA


 


351
GGCCGGCGAC CTCGTATTCT TCAACACCGG CGGCGCACAC CGCTACTCAC


 


401
ACGTCGGACT CTATATCGGC AACGGCGAAT TCATCCATGC CCCCAGCAGC


 


451
GGCAAAACCA TCAAAACCGA AAAACTCTCC ACACCGTTTT ACGCCAAAAA


 


501
CTACCTCGGC GCACATACTT TCTTTACAGA ATGA






This corresponds to the amino acid sequence <SEQ ID 720; ORF 206.a>:










a206.pep




1
MFPPDKTLFL CLSALLLASC GTTSGKHRQP KPKQTVRQIQ AVRISHIDRT


 


51
QGSQELMLHS LGLIGTPYKW GGSSTATGFD CSGMIQFVYK NALNVKLPRT


 


101
ARDMAAASRK IPDSRLKAGD LVFFNTGGAH RYSHVGLYIG NGEFIHAPSS


 


151
GKTIKTEKLS TPFYAKNYLG AHTFFTE*






m206/a206 99.4% identity in 177 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 721>:










g209.seq




1
atgctgcggc atttaggaaa cgacttcgcc ttgggcgcgt tgtttttcga


 


51
tgctgcggtt gatgtgccac tgctgggcga tggtcaggag gttgttgacc


 


101
acccagtaga gaaccaaacc ggcagggaag aagaagaaca tgacggagaa


 


151
aaccaacggc atgattttca tcattttcgc ctgcatcggg tcggtcggcg


 


201
gcgggttcag ataggtttgg gcgaacatcg ttgccgccat aatgatgggc


 


251
aggatgtagt aggggtcggc gcggctgagg tcggtaatcc agcccagcca


 


301
aggtgcctgg cgcaattcta cggaggcgaa caatgcccag tacaagccga


 


351
tgaagacggg gatttgcaac agcataggca gacagccgcc cagcgggttg


 


401
atttcctcgt cttcgaaaag ctgcatcatc gcttgctgtt gcgccatacg


 


451
gtcgtcgccg tatttttctt tgatggtctg cagttcgggt gcggcggcac


 


501
gcattttcgc catcgaacgg taggaggcgt tggtcaatgg atacagtacg


 


551
gctttgacga tgatggtcaa aacgacgatt gcccagcccc agttgccgat


 


601
aatgttgtgc agttggttca ggagccagaa gagcggcgat gcgaaccagt


 


651
gtactttacc gtagtctttt gccagttgca ggttgtcggc gatgtttgcg


 


701
ataacggatg tggtttgcgg accggcatac aggttgaccg ccattttcgg


 


751
ttttggcccc cgggttggga tagcggttaa






This corresponds to the amino acid sequence <SEQ ID 722; ORF 209.ng>:










g209.pep




1
MLRHLGNDFA LGALFFDAAV DVPLLGDGQE VVDHPVENQT GREEEEHDGE


 


51
NQRHDFHHFR LHRVGRRRVQ IGLGEHRCRH NDGQDVVGVG AAEVGNPAQP


 


101
RCLAQFYGGE QCPVQADEDG DLQQHRQTAA QRVDFLVFEK LHHRLLLRHT


 


151
VVAVFFFDGL QFGCGGTHFR HRTVGGVGQW IQYGFDDDGQ NDDCPAPVAD


 


201
NVVQLVQEPE ERRCEPVYFT VVFCQLQVVG DVCDNGCGLR TGIQVDRHFR


 


251
FWPPGWDSG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 723>:










m209.seq




1
ATGCTGCGGC ATTTAGGAAA CGACTTCGCC TTGGgGCGTT GTTTTTCGAT


 


51
GCTGCGGTTG ATGTGCCATT GCTGGGCGAT GGTCAGGAGG TTGTTGACTA


 


101
CCCAGTACAA TACCAGACCG GCAGGGAAGA AGAAGAACAT GACGGAGAAA


 


151
ACCAACGGCA TGATTTTCAT CATTTTCGCC TGCATCGGGT CGGTCGGCGG


 


201
CGGGTTCAGA TAAGTTTGGG CGAACATCGT TGCCGCCATA ATGATGGGCA


 


251
GGATGTAGTA GGGGTCGGCG CGGCTGAGGT CGGTAATCCA ACCCAGCCAA


 


301
GGTGCCTGGC GCAATTCTAC GGAGGCGAAC AATGCCCAAT ACAATCCGAT


 


351
GAAGACGGGG ATTTGCAACA GCATAGGCAG GCAGCCGCCC AGCGGGTTGA


 


401
TTTTCTCGTC TGTGTAAAGC TGCATCATCG CCTGTTGTTG CGCCATACGG


 


451
TCGTCGCCGT ATTTCTCTTT GATGGCTTGC AGTTTGGGTG CGGCGGCACG


 


501
CATTTTCGCC ATAGAGCGGT AAGAGGCGTT GGTCAATGGA TACAGTACGG


 


551
CTTTGACGAT GATGGTTAAA ACGATAATCG CCCAGCCCCA GTTGCCGATG


 


601
ATGTTGTGCA GTTGGTTCAG GAGCCAGAAG AGCGGGGAGG CGAACCAGTG


 


651
TACTTTGCCG TAGTCTTTGG CCAGTTGCAG GTTGTCGGCG ATGTTTGCGA


 


701
TGACGGATGT GGTCTGCGGG CCGGCGTAGA GGTTGATGGA GGCTTCGgTT


 


751
TCGCGCCGTT TTGGATGGCG GCTAAAGGCA CGCTGACGCT GGTGCTGTAC


 


801
AGCTTGTCGT TGCGGCGTTT GATGTCGATG TTGCACTCGC CTGCGGCGCA


 


851
AACGCTTTGT CTGCCTTTAG GTTGGAGAAT CCAGGTGGAC ATGAAGTGGT


 


901
GTTCAATCAT GCCGAGCCAG CCGGTCGGGG TTTTGCGGAT GTATTCGGCC


 


951
TCGGATTTGC CGGATTTGGC ATCGTCGTCC AAGTCGGAAA AGCTGACTTT


 


1001
TTGGAAGTTG CCTTCAGGGG TATAA






This corresponds to the amino acid sequence <SEQ ID 724; ORF 209>:










m209.pep




1
MLRHLGNDFA LGALFFDAAV DVPLLGDGQE VVDYPVQYQT GREEEEHDGE


 


51
NQRHDFHHFR LHRVGRRRVQ ISLGEHRCRH NDGQDVVGVG AAEVGNPTQP


 


101
RCLAQFYGGE QCPIQSDEDG DLQQHRQAAA QRVDFLVCVK LHHRLLLRHT


 


151
VVAVFLFDGL QFGCGGTHFR HRAVRGVGQW IQYGFDDDG* NDNRPAPVAD


 


201
DVVQLVQEPE ERGGEPVYFA VVFGQLQVVG DVCDDGCGLR AGVEVDGGFG


 


251
FAPFWMAAKG TLTLVLYSLS LRRLMSMLHS PAAQTLCLPL GWRIQVDMKW


 


301
CSIMPSQPVG VLRMYSASDL PDLASSSKSE KLTFWKLPSG V*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 209 shows 88.5% identity over a 253 aa overlap with a predicted ORF (ORF 209.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 725>:










a209.seq




1
ATGCTGCGGC ATTTAGGAAA CGACTTCGCC TTGGGCGCGT TGTTTTTCGA


 


51
TGCTGCGGTT GATGTGCCAT TGCTGGGCGA TGGTCAGGAG GTTGTTGATC


 


101
ACCCAGTACA ATACCAGACC GGCAGGGAAG AAGAAGAACA TGACGGAGAA


 


151
AACCAAAGGC ATGATTTTCA TCATTTTCGC CTGCATCGGG TCGGTCGGCG


 


201
GCGGGTTCAG ATAGGTTTGG GCGAACATCG TTGCCGCCAT AATGATGGGC


 


251
AGGATGTAGT AGGGGTCGGC GCGGCTGAGG TCGGTAATCC AACCCAGCCA


 


301
AGGTGCCTGG CGCAATTCTA CGGAGGCGAA CAATGCCCAA TACAATCCGA


 


351
TGAAGACGGG GATTTGCAAC AGCATAGGCA GGCAGCCGCC CAGCGGGTTG


 


401
ATTTTCTCGT CTGTGTAAAG CTGCATCATG GCTTGTTGCT GCGCCATACG


 


451
GTCGTCGCCG TATTTCTCTT TGATGGCTTG CAGTTTGGGC GCGGCGGCAC


 


501
GCATTTTCGC CATCGAACGG TAAGAGGCGT TGGTCAATGG ATACAGTACG


 


551
GCTTTGACGA TGATGGTTAA AACGATAATC GCCCAGCCCC AGTTGCCGAT


 


601
GATGTTGTGC AGTTGGTTCA AAAGCCAAAA GAGGGGGGAG GCGAACCAGT


 


651
GTACTTTGCC GTAGTCTTTG GCCAGTTGCA GGTTGTCGGC GATGTTTGCG


 


701
ATAACGGATG TGGTCTGTGG GCCGGCGTAG AGGTTGATGG AGGCTTCGGT


 


751
TTCGCACCGT TTTGGATAGC GGCTAAAGGC ACGCTGACGC TGGTGCTGTA


 


801
CAGCTTGTCG TTGCGGCGTT TGATGTCGAT ACGGCAGTCG CCAGCGGCGC


 


851
AAACGCTTTG TCCGCCTTTG GGTTGGAGGA TCCAGGTGGA CATGAAGTGG


 


901
TGTTCAATCA TGCCGAGCCA GCCGGTCGGG GTTTTGCGGA TGTATTCGGC


 


951
CTCGGATTTG CCGGATTTGG CATCGTCGTC CAAGTCGGAG AAGCTGACTT


 


1001
TTTGGAAGTT GCCTTCAGGG GTATAA






This corresponds to the amino acid sequence <SEQ ID 726; ORF 209.a>:










a209.pep




1
MLRHLGNDFA LGALFFDAAV DVPLLGDGQE VVDHPVQYQT GREEEEHDGE


 


51
NQRHDFHHFR LHRVGRRRVQ IGLGEHRCRH NDGQDVVGVG AAEVGNPTQP


 


101
RCLAQFYGGE QCPIQSDEDG DLQQHRQAAA QRVDFLVCVK LHHGLLLRHT


 


151
VVAVFLFDGL QFGRGGTHFR HRTVRGVGQW IQYGFDDDG* NDNRPAPVAD


 


201
DVVQLVQKPK EGGGEPVYFA VVFGQLQVVG DVCDNGCGLW AGVEVDGGFG


 


251
FAPFWIAAKG TLTLVLYSLS LRRLMSIRQS PAAQTLCPPL GWRIQVDMKW


 


301
CSIMPSQPVG VLRMYSASDL PDLASSSKSE KLTFWKLPSG V*






m209/a209 95.6% identity in 341 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 727>:










g211.seq




1
atgttgcgga ttgctgctgc caatcagttg ggcggtcgaa atggtgcggc


 


51
ggtgggaaac ggggtcgata agtttgggcg tggtgctgat aatcaggttg


 


101
agtttttgga aggaaacctg attgtagtcg gcgcgtccgg gcgtgccgct


 


151
gtaacggtag ccgtggcgca attcgagcgt gcgtttgttg tccttcagcg


 


201
agaagttacc ttctttggcg aagatgatgt tgtcgccgcc gtttttgtcc


 


251
tgttcgcgca ggaacaggtt tttcatgatg ccggattcgg tgtcaaaggt


 


301
ttcgacgaaa taaaccctgc cgttgcgctt gcccaagtta ttgaactcgc


 


351
cggcttccac caaagacaat tcctgcttct gcttcaaaat ttcggcatat


 


401
tcgcggctgc gcagctctgc ccacggtatc acccaaagct gcatgacggc


 


451
aatcaggatg gcaaacggca cggcaaactg catgacgggg cgtatccact


 


501
gtttcaacgc caatccgcag gatag






This corresponds to the amino acid sequence <SEQ ID 728; ORF 211.ng>:










g211.pep




1
MLRIAAANQL GGRNGAAVGN GVDKFGRGAD NQVEFLEGNL IVVGASGRAA


 


51
VTVAVAQFER AFVVLQREVT FFGEDDVVAA VFVLFAQEQV FHDAGFGVKG


 


101
FDEINPAVAL AQVIELAGFH QRQFLLLLQN FGIFAAAQLC PRYHPKLHDG


 


151
NQDGKRHGKL HDGAYPLFQR QSAG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 729>:










m211.seq




1
ATGTTGCGGG TTGCTGCTGC CAATCAGTTG GGCGGTCGGA ATGGTACGGC


 


51
GGTGGGAAAC GGGGTCGATG AGTTTGGGCG TGGTGCTGAT AATCAGGTTG


 


101
AGTTTTTGGA AGGAAACCTG ATTGTAGTCG GCGCGTCCGG GCGTGCCGCT


 


151
GTAACGGTAG CCGTGGCGCA ATTCGAGCGT GCGTTTGTTG TCGTTCAGCG


 


201
AGAAGTTACC TTCTTTGGCG AAGATGATGT TGTCGCCGCC GTTTTTGTCC


 


251
TGTTCGCGCA GGAACAGGTT TTTCATGATG CCGGATTCGG TATCGAAGGT


 


301
TTCGACAAAA TAAACCCTGC CGTTGCGCTT GCCCAAACTG TTGAACTCGC


 


351
CTGCCTCCAC CAAAGACAAT TCCTGCTTCT GCTTCAGGAT TTCAGCGTAT


 


401
TCGCGGCTGC GTAGCTCTGC CCACGGTATC ACCCAAAGCT GCATGACGGC


 


451
AACCAAAACG GCAAACGGCA CGGCAAACTG CATCACCGGG CGTATCCATT


 


501
GTTTCAATGC CAATCCGCAg GATAG






This corresponds to the amino acid sequence <SEQ ID 730; ORF 211>:










m211.pep




1
MLRVAAANQL GGRNGTAVGN GVDEFGRGAD NQVEFLEGNL IVVGASGRAA



 


51
VTVAVAQFER AFVVVQREVT FFGEDDVVAA VFVLFAQEQV FHDAGFGIEG


 


101
FDKINPAVAL AQTVELACLH QRQFLLLLQD FSVFAAAXLC PRYHPKLHDG


 


151
NQNGKRHGKL HHRAYPLFQC QSAG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 211 shows 89.1% identity over a 174 aa overlap with a predicted ORF (ORF 211.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 731>:










a211.seq




1
ATGTTGCGGG TTGCTGCTGC CAATCAGTTG GGCGGTCGGA ATGGTACGGC



 


51
GGTGGGAAAC GGGGTCGATG AGTTTGGGCG TGGTGCTGAT AATCAGGTTG


 


101
AGTTTTTGGA AGGAAACCTG ATTGTAGTCG GCGCGTCCGG GCGTGCCGCT


 


151
GTAACGGTAG CCGTGGCGCA ATTCGAGCGT GCGTTTGTTG TCGTTCAGCG


 


201
AGAAGTTACT TTCTTTGGCG AAGATGATGT TGTCGCCGCC GTTTTTGTCC


 


251
TGTTCGCGCA GGAACAGGTT TTTCATGATG CCGGATTCGG TATCGAAGGT


 


301
TTCGACAAAA TAAACCCTGC CGTTGCGCTT GCCCAAACTG TTGAACCCGC


 


351
CTGCCTCCAC CAAAGACAAT TCCTGCTTCT GCTTCAGGAT TTCAGCGTAT


 


401
TCGCGGCTGC GTAGCTCTGC CCACGGTATC ACCCAAAGCT GCATGACGGC


 


451
AACCAAAACG GCAAACGGCA CGGCAAACTG CATCACCGGG CGTATCCATT


 


501
GTTTCAATGC CAATCCGCAG GATAG






This corresponds to the amino acid sequence <SEQ ID 732; ORF 211.a>:










a211.pep




1
MLRVAAANQL GGRNGTAVGN GVDEFGRGAD NQVEFLEGNL IVVGASGRAA



 


51
VTVAVAQFER AFVVVQREVT FFGEDDVVAA VFVLFAQEQV FHDAGFGIEG


 


101
FDKINPAVAL AQTVEPACLH QRQFLLLLQD FSVFAAA*LC PRYHPKLHDG


 


151
NQNGKRHGKL HHRAYPLFQC QSAG*






m211/a71 1 99.4% identity in 174 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 733>:









g212.seq (partial)










1
atggacaatc tcgtatggga cggcattccc gacatccgca cactcgacca



 


51
aaccatccgc aaacacgcac acccgctcaa cctgattgtc tgcctccccg


 


101
ataatcagat tcccgatttt caaaccgcac aagatgcttc ggactcggaa


 


151
tgccgtctga agcaccgttt ggatcaggca acccagtgcc tccagttcga


 


201
cagcatcaac ctcatcgaac acatcctgcc cgatgtccgc ttctggctgg


 


251
ttcccccttc acgcacccgc cgcctgcacg aacacttcca ccacatttcc


 


301
tggcagaccg aagccatccc gcaaaccgaa agcaagtccg acaaaccctg


 


351
gtttgcactt ccacaaacat ccgaacggaa aaaaccggaa cacgtcctcg


 


401
tcatcggtgc aggcattgcc ggcgcatcga ccgcccacgc cttagcatca


 


451
cacggcattt ccgttaccgt attggaagcc cgaaaagccg ctcaagccgc


 


501
cagcggcaac cggcaagggc tgctttacgc caaaatctcg ccgcacgaca


 


551
ccggacagac cgaactgctg cttgccggct acggctacac caaacgcctg


 


601
ctcggacaca tcctgcccga ctccgacact tggggcggca acggcatcat


 


651
ccacctcaat tacagccgca ccgaacaaca acgcaatcac gaattgggtt


 


701
tgcaaaaaca ccataaccac ctctaccgca gcatcacgtc tgcagaagcc


 


751
gaaaaaatcg ccggcatccc gctgaacacg ccctacgccg aaccattatg


 


801
cggactctac tggcaacacg gcgtatggct caatccgccc gcattcgtcc


 


851
gcaccctcct cagccatccg ctgatcgaac tatatgaaaa cacaacgtta


 


901
accggcattt cccacgacgg agaaaagtgg attgcaagca cgccaaacgg


 


951
cacatttacc gccacacaca tcatctactg caccggcgcg cacagcccct


 


1001
gcctgcccga aaccaacctc gccgccctac ccctcaggca aatacgcgga


 


1051
caaaccggcc tcacaccgtc caccccgttt tccgaacaac tgcgttgcgc


 


1101
cgtttcaggc gaaagctaca tcagcccgtc gtggcacgga ctgcactgct


 


1151
acggcgcgag ttttattccc aacagcagca ataccggatg gaacgaagcc


 


1201
gaagaagcct caaaccgcca agcattggca caccttaacc ccgcccttgc


 


1251
cgaatcattg ttt...






This corresponds to the amino acid sequence <SEQ ID 734; ORF 212.ng>:









g212.pep (partial)










1
MDNLVWDGIP DIRTLDQTIR KHAHPLNLIV CLPDNQIPDF QTAQDASDSE



 


51
CRLKHRLDQA TQCLQFDSIN LIEHILPDVR FWLVPPSRTR RLHEHFHHIS


 


101
WQTEAIPQTE SKSDKPWFAL PQTSERKKPE HVLVIGAGIA GASTAHALAS


 


151
HGISVTVLEA RKAAQAASGN RQGLLYAKIS PHDTGQTELL LAGYGYTKRL


 


201
LGHILPDSDT WGGNGIIHLN YSRTEQQRNH ELGLQKHHNH LYRSITSAEA


 


251
EKIAGIPLNT PYAEPLCGLY WQHGVWLNPP AFVRTLLSHP LIELYENTTL


 


301
TGISHDGEKW IASTPNGTFT ATHIIYCTGA HSPCLPETNL AALPLRQIRG


 


351
QTGLTPSTPF SEQLRCAVSG ESYISPSWHG LHCYGASFIP NSSNTGWNEA


 


401
EEASNRQALA HLNPALAESL F...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 735>:










m212.seq




1
ATGGACAATC TCGTATGGGA CGGCATTCCC GACATCCGCA CACTCGACCA



 


51
AGCCATCCGC AAACACGCAC CCCCGCTCAA CCTGATTATC TGCCTCCCCG


 


101
ATAATCAGAT TCCCGATTTT CAAACCGCAC AAGATGCTTC GGACGCGGAA


 


151
TGCCGTCTGA AGCACCGTTT GGATCAGGCA ATGCAGTGCC TCCAGTTCGA


 


201
CAGCATCAAC CTCATCGAAC ACATCCTGCC CGATGTCCGC TTCTGGCTGG


 


251
TTCCCCCTTC ACGCACCCAC CACCTGCACG AACATTTCCA CCACATTTCC


 


301
TGGCAGACCG AAGCCATCCC GCAAACCGAA AGCAAGCCCG ACAAACCCTG


 


351
GTTTGCACTT CCACAAACAT CCGAACGGCA AAAACCGGAA CACATCCTCG


 


401
TTATCGGCGC GGGCATATCC GGCGCGGCAA CCGCCCACGC CTTAGCATCA


 


451
CACGGCATTT CCGTTACCGT ATTGGAAGCC CGAAAAGCCG CCCAAGCCGC


 


501
CAGCGGCAAC CGCCAAGGGC TGCTCTACGC CAAAATCTCG CCGCACGACA


 


551
CCGAACAGAC CGAACTTTTG CTTGCCGGCT ACGGCTACAC CAAACGCCTG


 


601
CTCGGACACA TCCTGCCCGA ATCCGAAACC TGGGGCGGCA ACGGCATCAT


 


651
CCACCTCAAT TACAGCCGCA CCGAACAACA ACGCAATCAC GAATTGGGTT


 


701
TGCAAAAACA CCATAACCAC CTCTACCGCA GCATCACATC TGCAGAAGCC


 


751
GAAAAAATCG CCGGTATCCC ACTGTCCGTC CCATACGACC ACCCTTCATG


 


801
CGGACTCTAC TGGCAACACG GCGTATGGCT CAATCCACCC GCATTCGTCC


 


851
GCACCCTCCT CAACCATCCG CTCATTGGAC TACACGAAGA CACACCCTTG


 


901
ACCGACATTT CCCACGACGG GGaAAAGTGG ATTGCAAGCA CGCCAAACGG


 


951
CACATTTACC GCCACACACA TCATCTACTG CACCGGTGCG AACAGCCCCT


 


1001
ACCTACCCGA AACCAACCTC GCCGCCCTGC CTCTCAGGCA AATACGCGGA


 


1051
CAAACCGGCC TCACACCGTC CACCCCGTTT TCCGAACAAC TGCGTTGCGC


 


1101
CGTTTCAGGC GAAAGCTACA TCAGCCCGTC GTGGCACGGA CTGCACTGCT


 


1151
ACGGCGCGAG TTTTATTCCC AACAGCAGCC ATACCGGATG GAACGAAGCC


 


1201
GAAGAAGCCT CAAACCGCCA AGCATTGGCA CACCTTAACC CCGCCCTTTC


 


1251
CGAATCATTG TTTGCCGCCA ACCCAAACCC CCAAAAACAC CAAGGGCACG


 


1301
CCGCCATACG CTGCGACAGC CCCGACCACC TTCCCCTAGT CGGCGCACTC


 


1351
GGCGACATTG CCGCCATGCG GCAGACCTAC ACCAAACTCG CGCTGGACAA


 


1401
AAACTACCGC ATCGACACCC CATGCCCATA CCTGCCTAAT GCCTACGTCA


 


1451
ACACCGCGCA CGGCACCCGC GGACTCGCCA CCGCCCCCAT CTGCGCCGCC


 


1501
GmCAwTGCAG CCCAAATCsT AGGCyTGCCC CATCCCTTTT yAcAAcGCCT


 


1551
gCGCCACGCC cTAcACCCCA ACCGCACCAT CATCCGCGCC ATCGTCAGAA


 


1601
GGAAGGATCT AACCCCTTAA






This corresponds to the amino acid sequence <SEQ ID 736; ORF 212>:










m212.pep




1
MDNLVWDGIP DIRTLDQAIR KHAPPLNLII CLPDNQIPDF QTAQDASDAE



 


51
CRLKHRLDQA MQCLQFDSIN LIEHILPDVR FWLVPPSRTH HLHEHFHHIS


 


101
WQTEAIPQTE SKPDKPWFAL PQTSERQKPE HILVIGAGIS GAATAHALAS


 


151
HGISVTVLEA RKAAQAASGN RQGLLYAKIS PHDTEQTELL LAGYGYTKRL


 


201
LGHILPESET WGGNGIIHLN YSRTEQQRNH ELGLQKHHNH LYRSITSAEA


 


251
EKIAGIPLSV PYDHPSCGLY WQHGVWLNPP AFVRTLLNHP LIGLHEDTPL


 


301
TDISHDGEKW IASTPNGTFT ATHIIYCTGA NSPYLPETNL AALPLRQIRG


 


351
QTGLTPSTPF SEQLRCAVSG ESYISPSWHG LHCYGASFIP NSSHTGWNEA


 


401
EEASNRQALA HLNPALSESL FAANPNPQKH QGHAAIRCDS PDHLPLVGAL


 


451
GDIAAMRQTY TKLALDKNYR IDTPCPYLPN AYVNTAHGTR GLATAPICAA


 


501
XXAAQIXGLP HPFXQRLRHA LHPNRTIIRA IVRRKDLTP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 212 shows 92.9% identity over a 421 aa overlap with a predicted ORF (ORF 212.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 737>:










a212.seq




1
ATGGACAATC TCGCATGGAA CGGCATTCCC GACATCCGCA CACTCGACCA



 


51
AACCATCCGC AAACACGCAC ACCCGCTCAA CCTGATTGTC TGCCTCCCCG


 


101
ATAATCAGAT TCCCAATTTT CAAACCGCAC AAGATGCTTC GGACGCGGAA


 


151
TGCCGTCTGA AGCACCGTTT GGATCAGGCA ACCCAGTGCC TCCAGTTCGA


 


201
CAGCATCAAC CTGATTGAAC ACATCCTGCC CGATGTCCGC TTCTGGCTGG


 


251
TTCCCCCTTC ACGCACCCGC CGCCTGCACG AACACTTCCA CCACATTTCC


 


301
TGGCAGACCG AAGCCATCCC GCAAACCGAA AGTAAGCCCG ACAAACCCTG


 


351
GTTTGCACTT CCACAAACAT CCGAACGGCA AAAACCGGAA CACATCCTCG


 


401
TTATCGGAGC GGGCATATCC GGCGCGGCAA CCGCCCACGC CTTAGCATCA


 


451
TACGGCATTT CCGTTACCGT ATTGGAAGCC CGAAAAGCCG CCCAAGCCGC


 


501
CAGCGGCAAC CGCCAAGGGC TGCTCTACGC CAAAATCTCG CCGCACGACA


 


551
CCGAACAAAC CGAACTGCTG CTTGCCGGCT ACGGCTACAC CAAACGCCTG


 


601
CTCGGACATA TCCTGCCCGA ATCCGAAACC TGGGGCGGCA ACGGCATCAT


 


651
CCACCTCAAT TACAGCCGCA CCGAACAACA ACGCAATCAC GAATTGGGTT


 


701
TGCAAAAACA CCATAACCAC CTCTACCGCA GCATCACGCA GGCAGAAGCC


 


751
GAAAAAATCG CCGGCATCCC TCTGAACACG CCCTACGCCG AACCATTATG


 


801
CGGACTGTTT TGGCAGTACG GCGTATGGCT CAATCCTCCC ACATTCGTCC


 


851
GCGCCCTCCT CAGCCATCCG CTCATTGGAC TACACGAAGA CACACCGTTA


 


901
ACCGACATTT CCCACGACGG GGAAAAGTGG ATTGCAAGCA CGCCAAACGG


 


951
CACATTTACC GCCACACACA TCATCTACTG CACCGGTGCG AACAGCCCCT


 


1001
ACCTACCCGA AACCAACCTC GCCACCCTGC CCCTCAGGCA AATACGCGGA


 


1051
CAAACCGGCC TCACACCGTC CACCCCGTTT TCCGAACAAC TGCGTTGCGC


 


1101
CGTTTCAGGC GAAAGCTACA TCAGCCCGTC GTGGCACGGA CTGCACTGCT


 


1151
ACGGCGCGAG TTTTATTCCC AACAGCAGCC ATACCGGATG GAACGAAGCC


 


1201
GAAGAAGCCT CAAACCGCCA AGCATTGGCA CACCTTAACC CCGCCCTTTC


 


1251
CGAATCATTG TTTGCCGCCA ACCCAAACCC CCAAAAACAC CAAGGGCACG


 


1301
CCGCCATACG CTGCGACAGC CCCGACCACC TTCCCCTAGT CGGCGCACTC


 


1351
GGCGACATTG CCGCTATGCA ACAAACTTAC GCCAAACTCG CGCTGGACAA


 


1401
AAACTATCGC ATCGATGCCC CCTGCCCGTA CCTGCCCAAT GCCTACGCCA


 


1451
ACACCGCCCA CGGCACACGC GGGCTTGCCA CCGCCCCCAT CTGCGCCGCC


 


1501
GCCGTTGCAG CCGAAATCCT AGGCTTGCCC CATCCCCTCT CAAAACGCCT


 


1551
GCGCCACGCC CTACACCCCA ACCGCGCCAT CATCCGCGCC ATCGTCAGAA


 


1601
GGAAGGATCT AACCCCTTAA






This corresponds to the amino acid sequence <SEQ ID 738; ORF 212.a>:










a212.pep




1
MDNLAWNGIP DIRTLDQTIR KHAHPLNLIV CLPDNQIPNF QTAQDASDAE



 


51
CRLKHRLDQA TQCLQFDSIN LIEHILPDVR FWLVPPSRTR RLHEHFHHIS


 


101
WQTEAIPQTE SKPDKPWFAL PQTSERQKPE HILVIGAGIS GAATAHALAS


 


151
YGISVTVLEA RKAAQAASGN RQGLLYAKIS PHDTEQTELL LAGYGYTKRL


 


201
LGHILPESET WGGNGIIHLN YSRTEQQRNH ELGLQKHHNH LYRSITQAEA


 


251
EKIAGIPLNT PYAEPLCGLF WQYGVWLNPP TFVRALLSHP LIGLHEDTPL


 


301
TDISHDGEKW IASTPNGTFT ATHIIYCTGA NSPYLPETNL ATLPLRQIRG


 


351
QTGLTPSTPF SEQLRCAVSG ESYISPSWHG LHCYGASFIP NSSHTGWNEA


 


401
EEASNRQALA HLNPALSESL FAANPNPQKH QGHAAIRCDS PDHLPLVGAL


 


451
GDIAAMQQTY AKLALDKNYR IDAPCPYLPN AYANTAHGTR GLATAPICAA


 


501
AVAAEILGLP HPLSKRLRHA LHPNRAIIRA IVRRKDLTP*






m212/n212 93.7% identity in 539 an overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 739>:










g214.seq




1
atgatacaaa agatatgtaa gctatttgtt ttaattgtaa tttttgcaac



 


51
ttctcccgct tttgcccttc aaagcgacag cagacggccc atccaaatcg


 


101
aagccgacca aggttcgctc gatcaagcca accaaaggac cacatttagc


 


151
ggcaatgtca tcatcagaca gggtacgctc aacatttccg cctcgtgtgt


 


201
caacgtcaca cgcggcaggc aaaggcggcg aatccgtgag ggcggaaggt


 


251
tcgcccgtcc gcttcagcca aacgttggac gggggcaaag ggacggtgcg


 


301
cggtcaggca aacaacgtta cctattcctc cgcaggaagc actgtcgttc


 


351
tgaccggcaa tgccaaagtg cagcgcggcg gcgacgttgc cgaaggtgcg


 


401
gtcattacct acaacaccaa aaccgaagtc tataccatca acggcagcac


 


451
gaaatcgggt gcgaaatccg cttccaaaac cggcagggtc agcgtcgtca


 


501
tccagccttc aagcacacaa aaaaccgaat aaccccgatg ccgtctgaaa


 


551
cggaaacgca gttcagacgg catttgccga ccgaaatgcc gagaagagat


 


601
tattga






This corresponds to the amino acid sequence <SEQ ID 740; ORF 214.ng>:










g214.pep




1
MIQKICKLFV LIVIFATSPA FALQSDSRRP IQIEADQGSL DQANQRTTFS



 


51
GNVIIRQGTL NISASCVNVT RGRQRRRIRE GGRFARPLQP NVGRGQRDGA


 


101
RSGKQRYLFL RRKHCRSDRQ CQSAARRRRC RRCGHYLQHQ NRSLYHQRQH


 


151
EIGCEIRFQN RQGQRRHPAF KHTKNRITPM PSETETQFRR HLPTEMPRRD


 


201
Y






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 741>:









m214.seq (partial)










1
ATGATACAAA AGATATGTAA GCTATTTGTT TTAATAGCAT TTTTTTCGGC



 


51
GTCCCCCGCT TTTGCCCTTC AAAGCGACAG CAGGCAGCCT ATTCAGATTG


 


101
AGGCCGACCA AGGTTCGCTC GATCAAGCCA ACCAAAGCAC CACATTCAGC


 


151
GGAAACGTCG TCATCAGACA GGGTACGCTC AATATTTCCG CCGCCCGCGT


 


201
CAATGTTACA CGCGGCGGCA AAGGCGGCGA ATCCGTGAGG GCGGAAGGTT


 


251
CGCCAGTCCG CTTCAGCCAG ACATTGGACG GCGGCAAAGG CACGGTGCGC


 


301
GGACAGGCAA ACAACGTTGC TTATTCATCT GCAGGCAGCA CCGTAGTCTT


 


351
AACCGGTAAT GCCAAAGTAC AGCGCGGCGG CGATGTCGCC GAAGGTGCGG


 


401
TGATTACATA CAACACCAAA ACCGAAGTCT ATACCATCAG CGGCAGCACA


 


451
AAATT...






This corresponds to the amino acid sequence <SEQ ID 742; ORF 214>:









m214.pep (partial)










1
MIQKICKLFV LIAFFSASPA FALQSDSRQP IQIEADQGSL DQANQSTTFS



 


51
GNVVIRQGTL NISAARVNVT RGRQRRRIRE GGRFASPLQP DIGRRQRHGA


 


101
RTGKQRCLFI CRQHRSLNR* CQSTARRRCR RRCGDYIQHQ NRSLYHQRQH


 


151
KI...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 214 shows 80.3% identity over a 152 aa overlap with a predicted ORF (ORF 214.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 743>:










a214.seq




1
ATGATACAAA AGATATGTAA GCTATTTGTT TTAATAGCAT TTTTTTCGGC



 


51
GTCCCCCGCT TTTGCCCTTC AAAGCGACAG CAGGCAGCCT ATTCAGATTG


 


101
AGGCCGACCA AGGTTCGCTC GATCAAGCCA ACCAAAGCAC CACATTCAGC


 


151
GGAAACGTCG TCATCAGACA GGGTACGCTC AATATTTCCG CCGCCCGCGT


 


201
CAATGTTACA CGCGGC.GGC AAAGGCGGCG AATCCGTGAG GGCGGAAGGT


 


251
TCGCCAGTCC GCTTCAGCCA GACATTGGAC GGCGGCAAAG GCACGGTGCG


 


301
CGGACAGGCA AACAACGTTG CTTATTCATC TGCAGGCAGC ACCGTAGTCT


 


351
TAACCGGTAA TGCCAAAGTA CAGCGCGGCG GCGATGTCGC CGAAGGTGCG


 


401
GTGATTACAT ACAACACCAA AACCGAAGTC TATACCATCA GCGGCAGCAC


 


451
AAAATCCGGC GCAAAATCCG CTTCCAAATC CGGCAGGGTC AGCGTCGTTA


 


501
TCCAGCCTTC GAGTACGCAA AAATCCGAAT AATCCCAATG CCGTCTGAAA


 


551
CATAAACCTG GTTCGGACGG CATTTGCCGA CCGAAATATT GAAGAGATAT


 


601
TTATGA






This corresponds to the amino acid sequence <SEQ ID 744; ORF 214.a>:










a214.pep




1
MIQKICKLFV LIAFFSASPA FALQSDSRQP IQIEADQGSL DQANQSTTFS



 


51
GNVVIRQGTL NISAARVNVT RGXQRRRIRE GGRFASPLQP DIGRRQRHGA


 


101
RTGKQRCLFI CRQHRSLNR* CQSTARRRCR RRCGDYIQHQ NRSLYHQRQH


 


151
KIRRKIRFQI RQGQRRYPAF EYAKIRIIPM PSET*TWFGR HLPTEILKRY


 


201
L*






m214/a214 99.3% identity in 152 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 745>:










g214-1.seq




1
ATGATACAAA AGATATGTAA GCTATTTGTT TTAATTGTAA TTTTTGCAAC



 


51
TTCTCCCGCT TTTGCCCTTC AAAGCGACAG CAGACGGCCC ATCCAAATCG


 


101
AAGCCGACCA AGGTTCGCTC GATCAAGCCA ACCAAAGTAC CACATTTAGC


 


151
GGCAATGTCA TCATCAGACA GGGTACGCTC AACATTTCCG CCTCGCGCGT


 


201
CAACGTCACA CGCGGCGGCA AAGGCGGCGA ATCCGTGAGG GCGGAAGGTT


 


251
CGCCCGTCCG CTTCAGCCAA ACGTTGGACG GGGGCAAAGG GACGGTGCGC


 


301
GGTCAGGCAA ACAACGTTAC CTATTCCTCC GCAGGAAGCA CCGTCGTTCT


 


351
GACCGGCAAT GCCAAAGTGC AGCGCGGCGG CGACGTTGCC GAAGGTGCGG


 


401
TCATTACCTA CAACACCAAA ACCGAAGTCT ATACCATCAA CGGCAGCACG


 


451
AAATCGGGTG CGAAATCCGC TTCCAAAACC GGCAGGGTCA GCGTCGTCAT


 


501
CCAGCCTTCA AGCACACAAA AAACCGAATA A






This corresponds to the amino acid sequence <SEQ ID 746; ORF 214-1.ng>:










g214-1.pep




1
MIQKICKLFV LIVIFATSPA FALQSDSRRP IQIEADQGSL DQANQSTTFS



 


51
GNVIIRQGTL NISASRVNVT RGGKGGESVR AEGSPVRFSQ TLDGGKGTVR


 


101
GQANNVTYSS AGSTVVLTGN AKVQRGGDVA EGAVITYNTK TEVYTINGST


 


151
KSGAKSASKT GRVSVVIQPS STQKTE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 747>:










m214-1.seq




1
ATGATACAAA AGATATGTAA GCTATTTGTT TTAATAGCAT TTTTTTCGGC



 


51
GTCCCCCGCT TTTGCCCTTC AAAGCGACAG CAGGCAGCCT ATTCAGATTG


 


101
AGGCCGACCA AGGTTCGCTC GATCAAGCCA ACCAAAGCAC CACATTCAGC


 


151
GGAAACGTCG TCATCAGACA GGGTACGCTC AATATTTCCG CCGCCCGCGT


 


201
CAATGTTACA CGCGGCGGCA AAGGCGGCGA ATCCGTGAGG GCGGAAGGTT


 


251
CGCCAGTCCG CTTCAGCCAG ACATTGGACG GCGGCAAAGG CACGGTGCGC


 


301
GGACAGGCAA ACAACGTTGC TTATTCATCT GCAGGCAGCA CCGTAGTCTT


 


351
AACCGGTAAT GCCAAAGTAC AGCGCGGCGG CGATGTCGCC GAAGGTGCGG


 


401
TGATTACATA CAACACCAAA ACCGAAGTCT ATACCATCAG CGGCAGCACA


 


451
AAATCCGGCG CAAAATCCGC TTCCAAATCC GGCAGGGTCA GCGTCGTTAT


 


501
CCAGCCTTCG AGTACGCAAA AATCCGAATA A






This corresponds to the amino acid sequence <SEQ ID 748; ORF 214-1>:










m214-1.pep




1
MIQKICKLFV LIAFFSASPA FALQSDSRQP IQIEADQGSL DQANQSTTFS



 


51
GNVVIRQGTL NISAARVNVT RGGKGGESVR AEGSPVRFSQ TLDGGKGTVR


 


101
GQANNVAYSS AGSTVVLTGN AKVQRGGDVA EGAVITYNTK TEVYTISGST


 


151
KSGAKSASKS GRVSVVIQPS STQKSE*






m214-1/g214-1 93.8% identity in 176 aa overlap





g214-1/p38685









sp|P38685|YHBN_ECOLI 17.3 KD PROTEIN IN MURA-RPON INTERGENIC REGION



PRECURSOR (ORF185)


>gi|551336 (U12684) orf185 [Escherichia coli] >gi|606139


(U18997) ORF_o185 [Escherichia coli]


>gi|1789592 (AE000399) orf, hypothetical protein [Escherichia coli]


Length = 185 Score = 97.1 bits (238), Expect = 6e−20


Identities = 57/126 (45%), Positives = 74/126 (58%), Gaps = 3/126 (2%)











Query:
19
PAFALQSDSRQPIQIEADQGSLDQANQSTTFSGNVVIRQGTLNISAARVNVTR--GGKGG
76





PAFA+  D+ QPI IE+DQ SLD      TF+GNV++ QGT+ I+A +V VTR  G +G



Sbjct:
24
PAFAVTGDTDQPIHIESDQQSLDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGK
83


 


Query:
77
ESVRAEGSPVRFSQTLDGGKGTVRGQANNVAYSSAGSTVVLTGNAKVQRGGDVAEGAVIT
136




E +   G P  F Q  D GK  V G A+ + Y  A   VVLTGNA +Q+     +G  IT



Sbjct:
84
EVIDGYGKPATFYQMQDNGK-PVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKIT
142


 


Query:
137
YNTKTE
142




Y  K +



Sbjct:
143
YLVKEQ
148






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 749>:










a214-1.seq




1
ATGATACAAA AGATATGTAA GCTATTTGTT TTAATAGCAT TTTTTTCGGC



 


51
GTCCCCCGCT TTTGCCCTTC AAAGCGACAG CAGGCAGCCT ATTCAGATTG


 


101
AGGCCGACCA AGGTTCGCTC GATCAAGCCA ACCAAAGCAC CACATTCAGC


 


151
GGAAACGTCG TCATCAGACA GGGTACGCTC AATATTTCCG CCGCCCGCGT


 


201
CAATGTTACA CGCGGCGGCA AAGGCGGCGA ATCCGTGAGG GCGGAAGGTT


 


251
CGCCAGTCCG CTTCAGCCAG ACATTGGACG GCGGCAAAGG CACGGTGCGC


 


301
GGACAGGCAA ACAACGTTGC TTATTCATCT GCAGGCAGCA CCGTAGTCTT


 


351
AACCGGTAAT GCCAAAGTAC AGCGCGGCGG CGATGTCGCC GAAGGTGCGG


 


401
TGATTACATA CAACACCAAA ACCGAAGTCT ATACCATCAG CGGCAGCACA


 


451
AAATCCGGCG CAAAATCCGC TTCCAAATCC GGCAGGGTCA GCGTCGTTAT


 


501
CCAGCCTTCG AGTACGCAAA AATCCGAATA A






This corresponds to the amino acid sequence <SEQ ID 750; ORF 214-1.a>:










a214-1.pep




1
MIQKICKLFV LIAFFSASPA FALQSDSRQP IQIEADQGSL DQANQSTTFS



 


51
GNVVIRQGTL NISAARVNVT RGGKGGESVR AEGSPVRFSQ TLDGGKGTVR


 


101
GQANNVAYSS AGSTVVLTGN AKVQRGGDVA EGAVITYNTK TEVYTISGST


 


151
KSGAKSASKS GRVSVVIQPS STQKSE*






a214-1/m214-1 100.0% identity in 176 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 751>:










g215.seq




1
atgaaagtaa gatggcggta cggaattgcg ttcccattga tattggcggt



 


51
tgccttgggc agcctgtcgg catggttggg ccgtatcagc gaagtcgaaa


 


101
tcgaggaagt caggctcaat cccgacgaac ctcaatacac aatggacggc


 


151
ttggacggaa ggcggtttga cgaacaggga tacttgaaag aacatttgag


 


201
cgcgaaaggt gcgaaacagt ttcccgaaaa cagcgacatc cattttgatt


 


251
cgccgcatct cgtgttcttc caagaaggca ggctgttgta cgaagtcggc


 


301
agcgatgaag ccgtttacca taccgaaaac aaacaggttc tttttaaaaa


 


351
caacgttgtg ctgaccaaaa ccgccgacgg caggcggcag gcgggtaaag


 


401
tcgaaaccga aaaactgcac gtcgataccg aatctcaata tgcccaaacc


 


451
gatacgcctg tcagtttcca atatggcgcg tcgcacggtc aggcgggcgg


 


501
tatgacctac aaccacaaaa caggcatgtt gaacttctca tctaaagtga


 


551
aagccgcgat ttatgataca aaagatatgt aa






This corresponds to the amino acid sequence <SEQ ID 752; ORF 215.ng>:










g215.pep




1
MKVRWRYGIA FPLILAVALG SLSAWLGRIS EVEIEEVRLN PDEPQYTMDG



 


51
LDGRRFDEQG YLKEHLSAKG AKQFPENSDI HFDSPHLVFF QEGRLLYEVG


 


101
SDEAVYHTEN KQVLFKNNVV LTKTADGRRQ AGKVETEKLH VDTESQYAQT


 


151
DTPVSFQYGA SHGQAGGMTY NHKTGMLNFS SKVKAAIYDT KDM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 753>:









m215.seq (partial)










1
..AGCCTGTCGG CATGGTTGGG TCGTATCAGC GAAGTCGAGA TTGAAGAAGT



 


51
  CAGGCTCAAT CCCGACGAAC CGCAATACAC AATGGACAGC TTGGACGGCA


 


101
  GGCGGTTTGA CGAACAGGGA TACTTGAAAG AACATTTGAG CGCGAAGGGC


 


151
  GCGAAACAGT TTCCGGAAAG CAGCGACATC CATTTTGATT CGCCGCATCT


 


201
  CGTGTTCTTC CAAGAAGGCA GGTTGTTGTA CGAAGTCGGC AGCGACGAAG


 


251
  CCGTTTACCA TACCGAAAAC AAACAGGTTC TTTTTAAAAA CAACGTTGTG


 


301
  CTGACCAAAA CCGCCGACGG CAAACGGCAG GCGGGTAAAG TTGAAGCCGA


 


351
  AAAGCTGCAC GTCGATACCG AATCTCAATA TGCCCAAACC GATACGCCTG


 


401
  CAGTTTCCA ATATGGTGCA TCGCACGGTC AGGCGGGCGG CATGACTTAC


 


451
  GACCACAwwA CAGGCATGTT GAACTTCTCA TCTAAAGTGA AAGCCACGAT


 


501
  TTATGATACA AAAGATATGT AA






This corresponds to the amino acid sequence <SEQ ID 754; ORF 215>:









m215.pep (partial)










1
..SLSAWLGRIS EVEIEEVRLN PDEPQYTMDS LDGRRFDEQG YLKEHLSAKG



 


51
  AKQFPESSDI HFDSPHLVFF QEGRLLYEVG SDEAVYHTEN KQVLFKNNVV


 


101
  LTKTADGKRQ AGKVEAEKLH VDTESQYAQT DTPVSFQYGA SHGQAGGMTY


 


151
  DHXTGMLNFS SKVKATIYDT KDM*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 215 shows 96.0% identity over a 173 aa overlap with a predicted ORF (ORF 215.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 755>:










a215.seq




1
ATGAAAGTAA GATGGCGGTA CGGAATTGCG TTCCCATTGA TATTGGCGGT



 


51
TGCCTTGGGC AGCCTGTCGG CATGGTTGGG ACGCATCAGC GAAGTCGAGA


 


101
TTGAAGAAGT CAGGCTCAAT CCCGACGAAC CGCAATACAC AATGGACGGA


 


151
TTGGATGGCA GGCGGTTTGA CGAACAGGGA TACTTGAAAG AACATTTGAG


 


201
TTCGAAGGGC GCGAAACAGT TTCCCGAAAG CAGCGACATT CATTTCGACT


 


251
CACCGCATCT CGTGTTCTTC CAAGAAGGCA GGTTGTTGTA CGAAGTCGGC


 


301
AGCGATGAAG CCGTTTACCA TACCGAAAAC AAACAGGTTC TTTTTAAAAA


 


351
CAACGTTGTG CTGACCAAAA CCGCCGACGG CAAACGGCAG GCGGGTAAAG


 


401
TTGAAGCCGA AAAGCTGCAC GTCGATACCG AATCTCAATA TGCCCAAACC


 


451
GATACGCCTG TCAGTTTCCA ATATGGTGCA TCGCACGGTC AGGCGGGCGG


 


501
CATGACTTAC GACCACAAAA CAGGCATGTT GAACTTCTCA TCTAAAGTGA


 


551
AAGCCACGAT TTATGATACA AAAGATATGT AA






This corresponds to the amino acid sequence <SEQ ID 756; ORF 215.a>:










a215.pep




1
MKVRWRYGIA FPLILAVALG SLSAWLGRIS EVEIEEVRLN PDEPQYTMDG



 


51
LDGRRFDEQG YLKEHLSSKG AKQFPESSDI HFDSPHLVFF QEGRLLYEVG


 


101
SDEAVYHTEN KQVLFKNNVV LTKTADGKRQ AGKVEAEKLH VDTESQYAQT


 


151
DTPVSFQYGA SHGQAGGMTY DHKTGMLNFS SKVKATIYDT KDM*






m215/a215 98.3% identity in 173 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 757>:









g216.seq (partial)










1
..atgatatcga tttcgagctc ggtacccagc gacgaaatca ccgccatcat



 


51
  ccccgcactc aaacgcaaag acattaccct cgtctgcatc accgcccgcc


 


101
  ccgattcaac catggcgcgc catgccgata tccacatcac cgcatcggtt


 


151
  tcgcaagaag cctgcccgtt ggggcttgcc ccgaccacca gcaccaccgc


 


201
  cgttatggct ttgggcgacg cgttggcggt cgtcctgctg cgcgcccgcg


 


251
  cgttcacgcc cgacgacttc gccttgatcc accctgccgg cagcctcggc


 


301
  aaacgcctgc ttttgcgcgt tgccgacatt atgcacaaag gcggcggcct


 


351
  gcccgccgtc cgactcggca cgcccttgaa aggagccatc gtcagcatga


 


401
  gcgagaaagg tttgggcatg tgggcgggaa cggacgggca aaggctgtct


 


451
  gaaaggcctt tttactga






This corresponds to the amino acid sequence <SEQ ID 758; ORF 216.ng>:









g216.pep (partial)










1
..MISISSSVPS DEITAIIPAL KRKDITLVCI TARPDSTMAR HADIHITASV



 


51
  SQEACPLGLA PTTSTTAVMA LGDALAVVLL RARAFTPDDF ALIHPAGSLG


 


101
  KRLLLRVADI MHKGGGLPAV RLGTPLKGAI VSMSEKGLGM WAGTDGQRLS


 


151
  ERPFY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 759>:










m216.seq




1
ATGGCAATGG CAGAAAACGG AAAATATCTC GACTGGGCAC GCGAAGTGTT


 


51
GCACGCCGAA GCGGAAGGCT TGCGCGAAAT TGCAGCGGAA TTGsACAAAA


 


101
ACTTCGTCCT TGCGGCAGAC GCGTTGTTGC ACTGCAAGGG CAGGGTCGTT


 


151
ATCACGGGCA TGGTCAAGTC GGGACATATC GGGCGCAAAA TGGCGGCAAC


 


201
TATGGCCTCG ACCGGCACGC CTGCGTTTTT CGTCCACCCT GCGGAAGCGG


 


251
CACACGgCGA TTTGGGTATG ATTGTGGACA rCGACGTGGT CGTCGCGATT


 


301
TCCAATTCCG GCGAAAGCGA CGAAATCGCC GCCATCATCC CCGCACTCAA


 


351
ACGCAAAGAC ATCACGCTTG TCTGCATCAC CGCCCGCCCC GATTCAACCA


 


401
TGGCGCGCCA TGCCGACATC CACATCACGG CGTCGGTTTC CAAAGAAGCC


 


451
TGCCCGCTGG GGCTTGCCCC GACCACCAGC ACCACCGCCG TCATGGCTTT


 


501
GGGCGATGCG TTGGCGGTCG TCCtGCTGCG CgcACGCGCG TTCACGCCCG


 


551
ACGATTTCGC CTTGAGCCAT CCTGCCGGCA GCCTCGGCAA ACGCCTACTT


 


601
TTGCGCGTTG CCGACATTAT GCACAAAGGC GGCGGCCTGC CTGCCGTCCG


 


651
ACTCGGCACG CCCTTGAAAG AAGCCATCGT CAGCATGAGT GAAAAAGGGC


 


701
TGGGCATGTT GGCGGTAACG GACGGGCAAG GCCGTCTGAA AGGCGTATTC


 


751
ACCGACGGCG ATTTGCGCCG CCTGTTTCAA GAATGCGACA ATTTTACCGG


 


801
TCTTTCGATA GACGAAGTCA TGCATACGCA TCCTAAAACC ATCTCCGCCG


 


851
AACGTCTCGC CACCGAAGCC CTGAAAGTCA TGCAGGCAAA CCATGTGAAC


 


901
GGGCTTCTGG TTACCGATGC AGATGGCGTG CTGATCGGCG CGCTGAATAT


 


951
GCACGACCTG CTGGCGGCAC GGATTGTATA G






This corresponds to the amino acid sequence <SEQ ID 760; ORF 216>:










m216.pep




1
MAMAENGKYL DWAREVLHAE AEGLREIAAE LXKNFVLAAD ALLHCKGRVV


 


51
ITGMVKSGHI GRKMAATMAS TGTPAFFVHP AEAAHGDLGM IVDXDVVVAI


 


101
SNSGESDEIA AIIPALKRKD ITLVCITARP DSTMARHADI HITASVSKEA


 


151
CPLGLAPTTS TTAVMALGDA LAVVLLRARA FTPDDFALSH PAGSLGKRLL


 


201
LRVADIMHKG GGLPAVRLGT PLKEAIVSMS EKGLGMLAVT DGQGRLKGVF


 


251
TDGDLRRLFQ ECDNFTGLSI DEVMHTHPKT ISAERLATEA LKVMQANHVN


 


301
GLLVTDADGV LIGALNMHDL LAARIV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 216 shows 91.8% identity over a 147 aa overlap with a predicted ORF (ORF 216.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitides <SEQ ID 761>:










a216.seq




1
ATGGCGATGG CAGGAAACGA AAAATATCTT GATTGGGCAC GCGAAGTGTT


 


51
GCACACCGAA GCGGAAGGCT TGCGCGAAAT TGCGGCGGAT TTGGACGAAA


 


101
ACTTCGCCCT TGCGGCGGAC GCGTTGTTGC ACTGCAAAGG CAGGGTCGTT


 


151
ATCACGGGCA TGGGCAAGTC GGGACATATC GGGCGCAAAA TGGCGGCAAC


 


201
CATGGCCTCG ACCGGCACGC CCGCGTTTTT CGTCCACCCT GCGGAAGCGG


 


251
CACACGGCGA TTTGGGCATG ATTGTGGACA ACGACGTGGT CGTCGCGATT


 


301
TCCAATTCCG GTGAAAGCGA CGAAATCGCC GCCATCATCC CCGCGCTCAA


 


351
ACGCAAAGAT ATCACGCTTG TCTGCATCAC CGCCCGCCCC GATTCAACCA


 


401
TGGCGCGCCA TGCCGACATC CACATCACGG CGTCGGTTTC CAAAGAAGCC


 


451
TGCCCGCTGG GGCTTGCCCC GACCACCAGC ACCACCGCCG TTATGGCTTT


 


501
GGGCGATGCG TTGGCGGTTG TCCTGCTGCG CGCCCGCGCG TTCACGCCCG


 


551
ACGACTTCGC CTTGAGCCAC CCTGCCGGCA GCCTCGGCAA ACGCCTACTT


 


601
TTGCGCGTTG CCGACATTAT GCACAAAGGC GGCGGCCTGC CTGCCGTCCG


 


651
ACTCGGCACG CCCTTGAAAG AAGCCATCGT CAGCATGAGT GAAAAAGGGC


 


701
TGGGCATGTT GGCGGTAACG GACGGGCAAG GCCGTCTGAA AGGCGTATTC


 


751
ACCGACGGCG ATTTGCGCCG CCTGTTTCAA GAATGCGACA ATTTTACCGG


 


801
TCTTTCGATA GACGAAGTCA TGCATACGCA TCCTAAAACC ATCTCCGCCG


 


851
AACGTCTCGC CACCGAAGCC CTGAAAGTCA TGCAGGCAAA CCATGTGAAC


 


901
GGGCTTCTGG TTACCGATGC AGATGGCGTG CTGATCGGCG CGCTGAATAT


 


951
GCACGACCTT TTGGCGGCGC GGATTGTATA G






This corresponds to the amino acid sequence <SEQ ID 762; ORF 216.a>:










a216.pep




1
MAMAGNEKYL DWAREVLHTE AEGLREIAAD LDENFALAAD ALLHCKGRVV


 


51
ITGMGKSGHI GRKMAATMAS TGTPAFFVHP AEAAHGDLGM IVDNDVVVAI


 


101
SNSGESDEIA AIIPALKRKD ITLVCITARP DSTMARHADI HITASVSKEA


 


151
CPLGLAPTTS TTAVMALGDA LAVVLLRARA FTPDDFALSH PAGSLGKRLL


 


201
LRVADIMHKG GGLPAVRLGT PLKEAIVSMS EKGLGMLAVT DGQGRLKGVF


 


251
TDGDLRRLFQ ECDNFTGLSI DEVMHTHPKT ISAERLATEA LKVMQANHVN


 


301
GLLVTDADGV LIGALNMHDL LAARIV*






m216/a216 97.2% identity in 326 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 763>:










g217.seq




1
atggcggatg acggtttgtt gcggcaactg tccgaaaaac ccagccaaag


 


51
tgctctcttc ctgccatttg acccattcgt tttcgaggtt ttggactgcc


 


101
ttttggtcat cgggcccggc ttgaaacaat gtttcaagca aatcccggca


 


151
acgcgccacc cattcgccga ccgtcgcagg ttgccgccat atccgggcaa


 


201
tatccgacag ggtttcgagg aaggcggcaa aacgtccgaa catggcggtt


 


251
tgattcacgt cggcatacca cgcgctgaca tcctgccaca tcgggttgcc


 


301
gccttcgggc agcatccagc ccaatatcat acggtctgcc gcctgcttcc


 


351
aggtaaacag ctgatccgtg ccgccgcgca tttctccgtc caatccccaa


 


401
tggacgttca aatcggcaac catatcgtgc aaaagcggca aatcgtcccc


 


451
ggtcagtccg aaacggcgca acacgggcgc ggtttccaaa agcgcgagca


 


501
ctttgccgac ttcaaaacgg ctttccagca agtcggacac gcactccaac


 


551
gcataaaaaa acggttgccg gcggctgatt ttcacgtccg aaacggaata


 


601
cggcaatgcc tgcgcgccgg gttgcgcctg tccgaacacg gcttccataa


 


651
aaggcgtata gggttcgata ttcggggtta a






This corresponds to the amino acid sequence <SEQ ID 764; ORF 217.ng>:










g217.pep..




1
MADDGLLRQL SEKPSQSALF LPFDPFVFEV LDCLLVIGPG LKQCFKQIPA


 


51
TRHPFADRRR LPPYPGNIRQ GFEEGGKTSE HGGLIHVGIP RADILPHRVA


 


101
AFGQHPAQYH TVCRLLPGKQ LIRAAAHFSV QSPMDVQIGN HIVQKRQIVP


 


151
GQSETAQHGR GFQKREHFAD FKTAFQQVGH ALQRIKKRLP AADFHVRNGI


 


201
RQCLRAGLRL SEHGFHKRRI GFDIRG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 765>:










m217.seq




1
ATGGCGGATG ACGGTGTGCG GCGGCAACTG TCCGGAAAAT TGCGCCAATT


 


51
CGGTTTCCGC CTrCCATTTG ACCCATTCGT TTTCAAGGTT TTGGACTGAC


 


101
TTTTGGTCAT CGGCTTCAGC TTGGAACAAT GTTTCAAGCA AATCCCGGCA


 


151
ACGCGCCACC CATTCGCCGA CCGTTGCGGG CTGCCGCCAT ATCCGTACAA


 


201
TATCCGTCAG GGTTTCGAGG AAGGCGGCAA AACGTCCGAA CATGGCGGTT


 


251
TGATTCACGT CGGCATACCA CGCGCTGACA TCCTGCCACA TCGGATTGCC


 


301
GCCTTTGGGC AGCATCCAGC CCAATATCAT GCGTTCTACC GCCTGCTTCC


 


351
AGGTGAACAG CTGATCCGTG CCGCCGCGCA TTTCTCCGTC CAAACCCCAG


 


401
TGGACGTTCA AATCGGCAAC CATGTCGTGC AAAAGCGGTA AATCGTCCTC


 


451
AGTCAGTCCG AAACGGCGCA ACACGGGCGC GGTTTCTAAA AGCACAAGCA


 


501
CTTTATCGAC TTCAAATCGG CTTTCCAACA AGTCGAACAG GCATGACAAA


 


551
GCATGAAACA GCGGTTGGCG GCGGCTGATT TTCACGTCTG ACACGGAATA


 


601
CGGCAATGCC TGCGCACCgG GctGCGCCTG TCCGAACACG GCTTCGATAA


 


651
AAGGCGTATA GGATTCGATA TTCGGGGTTA A






This corresponds to the amino acid sequence <SEQ ID 766; ORF 217>:










m217.pep




1
MADDGVRRQL SGKLRQFGFR LPFDPFVFKV LDXLLVIGFS LEQCFKQIPA


 


51
TRHPFADRCG LPPYPYNIRQ GFEEGGKTSE HGGLIHVGIP RADILPHRIA


 


101
AFGQHPAQYH AFYRLLPGEQ LIRAAAHFSV QTPVDVQIGN HVVQKRXIVL


 


151
SQSETAQHGR GFXKHKHFID FKSAFQQVEQ AXQSMKQRLA AADFHVXHGI


 


201
RQCLRTGLRL SEHGFDKRRI GFDIRG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 217 shows 80.5% identity over a 226 aa overlap with a predicted ORF (ORF 217.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 767>:










a217.seq




1
GTGGCGGATG ACGGTGTGCA GCGGCAACTG TCCGGAAAAT TGCGCCAATT


 


51
CGGTTTCCGC CTGCCATTTG ACCCATTCGT TTTCGAGGCT TTGGACTGCC


 


101
TTTTGGTCAT CGCCTTCGAC TTGGAACAAT GTTTCAAGCA AATCCCGGCA


 


151
ACGCGCCACC CATTCGTCAA CCGTCGCAGG TTGCCGCCAT ATCCGTACAA


 


201
TATCCGTCAG GGTTTCGAGG AAGGCGGCAA AACGTCCGAA CAGGGCGGTT


 


251
TGGTTCACGT CGGCATACCA CGCGCTGACC CCCTGCCACA TCGGATTGCC


 


301
GCCTTCGGGC AGCATCCAGC CCAATATCAT GCGTTCTACC GCCTGCTTCC


 


351
AGGTGAACAG CTGATCCGTG CCGCCGCGCA TTTCTCCGTC CAAACCCCAG


 


401
CGGACGTTCA AATCGGCAAC CATGTCGTGC AAAAGCGGCA AATCGTCCTC


 


451
AGTCAGTCCG AAATGGCGCA ACACGGGCGC GGTTTCTAAA AGCACAAGCA


 


501
CTTTATCGAC TTCAAATCGG CTTTCCAACA AGTCGAACAG GCATGACAAA


 


551
GCATGAAACA GCGGTTGTCG GCGGCTGATT TTCACATCCG AAACGGAATA


 


601
CGGCAATGCC TGCGCGCCGG GCTGCGCCTG TCCGAACACG GCTTCGATAA


 


651
AAGGCGTATA GGATTCGATA TTCGGGGTTA A






This corresponds to the amino acid sequence <SEQ ID 768; ORF 217.a>:










a217.pep




1
VADDGVQRQL SGKLRQFGFR LPFDPFVFEA LDCLLVIAFD LEQCFKQIPA


 


51
TRHPFVNRRR LPPYPYNIRQ GFEEGGKTSE QGGLVHVGIP RADPLPHRIA


 


101
AFGQHPAQYH AFYRLLPGEQ LIRAAAHFSV QTPADVQIGN HVVQKRQIVL


 


151
SQSEMAQHGR GF*KHKHFID FKSAFQQVEQ A*QSMKQRLS AADFHIRNGI


 


201
RQCLRAGLRL SEHGFDKRRI GFDIRG*






m217/a217 90.3% identity in 226 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 769>:










g218.seq




1
atggttgcgg tggatcctta tacggcaaaa gtggtcaaca ccatgccgcg


 


51
caatcagggt tggtatcaca ctatggatga aatccacggc gatatgatgc


 


101
tcggtgcggc aggcgattat cttttggaaa cggcagcttc actgaccatt


 


151
attatggttg tcagcggctt gtacctttgg tgggcgaaac agcgcggcat


 


201
taaagcgatg ctgctgccgc caaaaagcag ggcgcgttct tggtggcgga


 


251
atctgcacgg cgcgtttgga acttgggtgt cgttgatttt actgttgttc


 


301
tgcctgtcgg gtattgcttg ggcaggtatt tggggcggca aattcgtgca


 


351
ggcttggaat cagttcccgg ccggcaaatg gggtgtcgaa ccgaaccccg


 


401
tttcaatcgt gccgacccac ggcgaggtat tgaatgacgg caaggttaag


 


451
gaagtgccgt ggattttgga gcttatgcct atgcctgtct cagggacgac


 


501
tgtgggtgaa aacggcatta accccaccga gcccaataac attggaaacc


 


551
gtcgaccgtt tcgcgcggga aatcggtttc aaagggcgtt atcagttgaa


 


601
tttgcccaaa ggcgaggacg gggtatggac tttgtcgcag gattctatga


 


651
gttatga






This corresponds to the amino acid sequence <SEQ ID 770; ORF 218.ng>:










g218.pep




1
MVAVDPYTAK VVNTMPRNQG WYHTMDEIHG DMMLGAAGDY LLETAASLTI


 


51
IMVVSGLYLW WAKQRGIKAM LLPPKSRARS WWRNLHGAFG TWVSLILLLF


 


101
CLSGIAWAGI WGGKFVQAWN QFPAGKWGVE PNPVSIVPTH GEVLNDGKVK


 


151
EVPWILELMP MPVSGTTVGE NGINPTEPNN IGNRRPFRAG NRFQRALSVE


 


201
FAQRRGRGMD FVAGFYEL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 771>:










m218.seq




1
ATGGTCGCGG TCGATCCTTA TACGGCAAAA GTGGTCAGTA CCATGCCGCG


 


51
CAATCAGGGT TGGTATTACA CGATGGATGA AATCCACAGC GATATGATGC


 


101
TCGGTGCGGC AGGCGATTAT CTTTTGGAAA CGGCAGCTTC ACTGACCATT


 


151
ATTATGGTTG TCAGCGGCTT GTACCTTTGG TGGGTGAAAC GGCGCGGCAT


 


201
CAAGGCGATG CTGCTGCCGT CAAAAGGCAr GGCGCGTTCT TGGTGGCGGA


 


251
ATCTGCACGG CACGTTTGGA ACTTGGGTGT CGTTGATTTT GCTGTTGTTC


 


301
TGCCTGTCGG GTATTGCTTG GGCGGGTATT TGGGGCGGCA AGTTCGTACA


 


351
GGCTTGGAGT CAGTTCCCTG CCGGTAAATG GGGTGTCGAA CCGAACCCCG


 


401
TTTCAGTCGT GCCGACCCAC GGCGAGGTAT TGAATGACGG CAAGGTTAAG


 


451
GAAGTGCCGT GGGTTTTGGA GCTTACGCCT ATGCCTGTTT CAGGGACGaC


 


501
yGtgGGCAAA GACGGCATTA ACCCTGACGA GCCGATGACA TTGGAAACCG


 


551
TCGACCGCTT TGCGCGGnGA AATCGGTTTC AAAGGGCGTT ATCAGTTGAA


 


601
TTTGCCCAAA GGCGAGGACG GCGTATGGAC TTTGTCGCAG GATTCTATGA


 


651
GTTA






This corresponds to the amino acid sequence <SEQ ID 772; ORF 218>:










m218.pep




1
MVAVDPYTAK VVSTMPRNQG WYYTMDEIHS DMMLGAAGDY LLETAASLTI


 


51
IMVVSGLYLW WVKRRGIKAM LLPSKGXARS WWRNLHGTFG TWVSLILLLF


 


101
CLSGIAWAGI WGGKFVQAWS QFPAGKWGVE PNPVSVVPTH GEVLNDGKVK


 


151
EVPWVLELTP MPVSGTTVGK DGINPDEPMT LETVDRFARX NRFQRALSVE


 


201
FAQRRGRRMD FVAGFYEL






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 218 shows 87.2% identity over a 218 aa overlap with a predicted ORF (ORF 218.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 773>:










a218.seq




1
ATGGTCGCGG TCGATCCTTA TACGGCAAAA GTGGTCAGTA CCATGCCGCG



 


51
CAATCAGGGT TGGTATTACG CGATGGATGA AATCCACAGC GATATGATGC


 


101
TCGGTTCGAC AGGTGATTAT CTTTTGGAAA CGGCTGCATC GCTGACGATT


 


151
ATCATGATAA TCAGCGGTTT GTACCTTTGG TGGGTGAAAC GGCGCGGCAT


 


201
CAAGGCGATG CTGCTGCCGC CAAAAGGCAG GGCGCGTTCT TGGTGGCGGA


 


251
ATCTGCACGG CGCGTTTGGA ACTTGGGTGT CGTTGATTTT ACTGTTGTTC


 


301
TGCCTGTCGG GTATTGCTTG GGCAGGTATT TGGGGCGGCA AGTTCGTGCA


 


351
GGCTTGGAGT CAGTTCCCGG CAGGCAAATG GGGTGTCGAA CCGAACCCTG


 


401
TTTCAGTCGT GCCGACCCAC GGCGAGGTAT TGAATGACGG CAAGGTTAAG


 


451
GAAGTGCCGT GGGTTTTGGA GCTTACGCCT ATGCCTGTTT CAGGGACGAC


 


501
TGTGGGCAAA GACGGTATTA ACCCTGACGA GCCGATGACA TTGGAAACCG


 


551
TCGACCGTTT TGCGCGG.GA AATCGGTTTC AAAGGGCGTT ATCAGCTGAA


 


601
TTTGCCCAAA GGCGAGGACG GCGTATGGAC TTTGTCGCAG GATTCTATGA


 


651
GTTA






This corresponds to the amino acid sequence <SEQ ID 774; ORF 218.a>:










a218.pep




1
MVAVDPYTAK VVSTMPRNQG WYYAMDEIHS DMMLGSTGDY LLETAASLTI



 


51
IMIISGLYLW WVKRRGIKAM LLPPKGRARS WWRNLHGAFG TWVSLILLLF


 


101
CLSGIAWAGI WGGKFVQAWS QFPAGKWGVE PNPVSVVPTH GEVLNDGKVK


 


151
EVPWVLELTP MPVSGTTVGK DGINPDEPMT LETVDRFARX NRFQRALSAE


 


201
FAQRRGRRMD FVAGFYEL






m218/a218 95.9% identity in 218 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 775>:










g219.seq




1
atgacggcaa ggttaaggaa gtgccgtgga ttttggagct tatgcctatg



 


51
cctgtctcag ggacgactgt gggtgaaaac ggcattaacc ccaccgagcc


 


101
caataacatt ggaaaccgtc gaccgtttcg cgcgggaaat cggtttcaaa


 


151
gggcgttatc agttgaattt gcccaaaggc gaggacgggg tatggacttt


 


201
gtcgcaggat tctatgagtt atgacatgat cagcccgttt gccgaccgca


 


251
cggtacatat cgaccagtac agcggcgaga ttcttgccga catccgtttt


 


301
gacgattaca acccgttcgg caaatttatg gcggcaagca ttgcgctgca


 


351
tatggggact ttgggctggt ggagcgtgtt ggcgaacgtc gtgttctgcc


 


401
ttgccgtgat ttttatcggc atcagcggct gcgtgatgtg gtggaaacgc


 


451
cgtccgtccg gcgtggcggg cattgttcct ccggcgcaaa aaatcaaact


 


501
gcccgtctgg tgggcgatgg cattgccgct gctgttgatt gcactgcttt


 


551
tcccgaccgc gctgcttgcc attgccgtga tttggctgtt ggataccttg


 


601
ctgctgtcgc ggattcctgt gttgaggaaa tggtttaaat ga






This corresponds to the amino acid sequence <SEQ ID 776; ORF 219.ng>:










g219.pep




1
MTARLRKCRG FWSLCLCLSQ GRLWVKTALT PPSPITLETV DRFAREIGFK



 


51
GRYQLNLPKG EDGVWTLSQD SMSYDMISPF ADRTVHIDQY SGEILADIRF


 


101
DDYNPFGKFM AASIALHMGT LGWWSVLANV VFCLAVIFIG ISGCVMWWKR


 


151
RPSGVAGIVP PAQKIKLPVW WAMALPLLLI ALLFPTALLA IAVIWLLDTL


 


201
LLSRIPVLRK WFK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 777>:










m219.seq




1
ATGACGGCAA GGTTAAGGAA GTGCCGTGGG TTTTGGAGCT TACGCCTATG



 


51
CCTGTTTCAG GGACGaCyGt gGGCAAAGAC GGCATTAACC CTGACGAGCC


 


101
GATGACATTG GAAACCGTCG ACCGCTTTGC GCGGnGAAAT CGGTTTCAAA


 


151
GGGCGTTATC AGTTGAATTT GCCCAAAGGC GAGGACGGCG TATGGACTTT


 


201
GTCGCAGGAT TCTATGAGTT ACGACATGAT CAGCCCGTTT GCCGACCGCA


 


251
CGGTACATAT CGACCAGTAC AGCGGCAAAA TCCTTGCCGA CATCCGTTTT


 


301
GACGATTACA ACCCGTTCGG CAAATTTATG GCGGCAAGCA TTGCGCTGCA


 


351
TATGGGGACT CTGGGCTGGT GGAGCGTGTT GGCGAACGTC TTGTTCTGCC


 


401
TTGCCGTCAT TTTTATCGGT ATCAGCGGCT GCGTGATGTG GTGGAAACGC


 


451
CGTCCGACCG GAGCGGTGGG CATCGTTCCG CCGGCGCAGA AAGTCAAGCT


 


501
GCCGGTTTGG TGGATGATGG CATTGCCGCT ATTGGCAATC GCACTGCTCT


 


551
TCCCGACCTC ACTGCTTGCC ATTGCCGTGA TTTGGCTGTT GGATACGCTG


 


601
CTGTTGTCGC GGATTCCTGT TTTGAGGAGA TGGTTTAAAT GA






This corresponds to the amino acid sequence <SEQ ID 778; ORF 219>:










m219.pep




1
MTARLRKCRG FWSLRLCLFQ GRXWAKTALT LTSRXHWKPS TALRGEIGFK



 


51
GRYQLNLPKG EDGVWTLSQD SMSYDMISPF ADRTVHIDQY SGKILADIRF


 


101
DDYNPFGKFM AASIALHMGT LGWWSVLANV LFCLAVIFIG ISGCVMWWKR


 


151
RPTGAVGIVP PAQKVKLPVW WMMALPLLAI ALLFPTSLLA IAVIWLLDTL


 


201
LLSRIPVLRR WFK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 219 shows 86.9% identity over a 213 aa overlap with a predicted ORF (ORF 219.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 779>:










a219.seq




1
ATGACGGCAA GGTTAAGGAA GTGCCGTGGG TTTTGGAGCT TACGCCTATG



 


51
CCTGTTTCAG GGACGACTGT GGGCAAAGAC GGTATTAACC CTGACGAGCC


 


101
GATGACATTG GAAACCGTCG ACCGTTTTGC GCGG.GAAAT CGGTTTCAAA


 


151
GGGCGTTATC AGCTGAATTT GCCCAAAGGC GAGGACGGCG TATGGACTTT


 


201
GTCGCAGGAT TCTATGAGTT ACGACATGAT CAGCCCGTTT GCTGACCGCA


 


251
CGGTGCATAT CGACCAGTAC AGCGGCAAGA TTCTTGCCGA CATCCGTTTT


 


301
GACGATTACA ACCCGTTCGG CAAATTTATG GCGGCAAGCA TTGCGCTGCA


 


351
TATGGGGACT TTGGGCTGGT GGAGCGTGTT GGCGAACGTT TTGTTCTGCC


 


401
TTGCCGTGAT TTTTATCGGC ATCAGCGGCT GCGTGATGTG GTGGAAACGC


 


451
CGTCCGTCCG GCGCGGTGGG CATGGTTCCG CCGGCGCAAA AAATCAAGCT


 


501
GCCCGTCTGG TGGGCAATGG CGGTGCCGCT GCTGCTGATT GCATTGCTTT


 


551
TCCCGACCGC GTTGCTTGCC ATTGCCGTGA TTTGGCTGTT GGATACGCTG


 


601
CTGTTGTCGC GGATTCCTGT TTTGAGGAGA TGGTTTAAAT GA






This corresponds to the amino acid sequence <SEQ ID 780; ORF 219.a>:










a219.pep




1
MTARLRKCRG FWSLRLCLFQ GRLWAKTVLT LTSR*HWKPS TVLRXEIGFK



 


51
GRYQLNLPKG EDGVWTLSQD SMSYDMISPF ADRTVHIDQY SGKILADIRF


 


101
DDYNPFGKFM AASIALHMGT LGWWSVLANV LFCLAVIFIG ISGCVMWWKR


 


151
RPSGAVGMVP PAQKIKLPVW WAMAVPLLLI ALLFPTALLA IAVIWLLDTL


 


201
LLSRIPVLRR WFK*






m219/a219 94.8% identity in 213 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 781>:










g221.seq




1
atgcacgacc acggcgccat ggatcgccgc ctccccgctt tcggaagtct



 


51
gatgcggcga gccgtaaatc adatcgacgc tgacggattt gaaccctgcc


 


101
tcacgggcgg catcgatgac ttctttggtt tcttcgtagc tttggatgcg


 


151
gttgactgcc gcctgcactt tggggtcgaa atcctgaatg ccgacgctca


 


201
tgcggttgaa gccgagtctg ccgagcatga ggacggtgtc gcggctgact


 


251
ttgcgcgggt cgatttcgat ggaatattcg ccggacggta tcagttcgaa


 


301
atgtttgcgg atcatgcgga agacacgttc gatctgttcg tcgctcaaaa


 


351
aggtcggcgt gccgccgccg aagtgcagtt gggcaagctg gtgccgtccg


 


401
ttcagatgtg gagcgagcag ttccatttct ttttcaagat attcgatgta


 


451
ggtatcggcg cggcttttgt ctttggtgat gattttgttg cagccgcagt


 


501
agtagcagat ggtgttgcaa aacggaatgt gaatgtaaag ggaaagcggt


 


551
ttgtttaa






This corresponds to the amino acid sequence <SEQ ID 782; ORF 221.ng>:










g221.pep




1
MHDHGAMDRR LPAFGSLMRR AVNXIDADGF EPCLTGGIDD FFGFFVALDA



 


51
VDCRLHFGVE ILNADAHAVE AESAEHEDGV AADFARVDFD GIFAGRYQFE


 


101
MFADHAEDTF DLFVAQKGRR AAAEVQLGKL VPSVQMWSEQ FHFFFKIFDV


 


151
GIGAAFVFGD DFVAAAVVAD GVAKRNVNVK GKRFV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 783>:










m221.seq




1
ATGGyGGTTT TGATGcwcmg AAGTCTGGTG CGGCAGGCCG TAAATCAAAT



 


51
CGACGCTGAC GGATTTGAAC CCCGCTTCGC GCGCCGCATC GATGACTTCT


 


101
TTGGTTTCTT CGTAACTTTG GATGCGGTTG ACCGCCGCCT GCACTTTGGG


 


151
GTCGAAATCC TGAATGCCGA TGCTCATGCG GTTGAAGCCG AGTCTGCCGA


 


201
GCATGAGGAC GGTGTCGCGG CTGACTTTGC GCGGGTCGAT TTCGATGGAG


 


251
TATTCGCCGG TGGGGATTAA CTCGAAATGT TTGCGTATCA TGCGGAAGAC


 


301
ACGTTCGATC TGTTCGTCGC TCAAAAAGGt GCGTGCcCCG CCGAAGTGCA


 


351
GTTGGGCAAG CTGGTGCCGT CCGTTCAGAT GTGGAGCGAG CAGTTCCATT


 


401
TCTTTTTCAA GATATTCGAT GTAGGCATCG GCGCGGCTTT TGTCTTTGGT


 


451
GATGATTTTG TTGCAGCCGC AGTAGTAGCA GATGGTGTTG CAGAACGGAA


 


501
TGTGAATGTA AAGGGAAAGC GGTTTGTTTA A






This corresponds to the amino acid sequence <SEQ ID 784; ORF 221>:










m221.pep




1
MXVLMXRSLV RQAVNQIDAD GFEPRFARRI DDFFGFFVTL DAVDRRLHFG



 


51
VEILNADAHA VEAESAEHED GVAADFARVD FDGVFAGGDX LEMFAYHAED


 


101
TFDLFVAQKG ACPAEVQLGK LVPSVQMWSE QFHFFFKIFD VGIGAAFVFG


 


151
DDFVAAAVVA DGVAERNVNV KGKRFV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 221 shows 87.6% identity over a 170 aa overlap with a predicted ORF (ORF 221.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 785>:










a221.seq




1
ATGGTGGTTT TGATGCTCCG AAGTCTGGTG CGGCAGGCCG TAAATCAAAT



 


51
CGACGCTGAC GGATTTGAAC CCCGCTTCGC GCGCCGCATC GATGACTTCT


 


101
TTGGTTTCTT CGTAACTTTG GATGCGGTTG ACCGCCGCCT GCACTTTGGG


 


151
GTCGAAATCC TGAATGCCGA TGCTCATGCG GTTGAAGCCG AGTCTGCCGA


 


201
GCATGAGGAC GGTGTCGCGG CTGACTTTGC GCGGGTCGAT TTCGATGGAG


 


251
TATTCGCCGG TGGGGATTAA CTCGAAATGT TTGCGTATCA TGCGGAAGAC


 


301
ACGTTCGATT TGGTCGTCGC TCAAAAAGGT CGGCGTGCCG CCGCCGAAGT


 


351
GCAGTTGGGC AAGCTGGTGC CGTCCGTTCA GATGTGGAGC GAGCAGTTCC


 


401
ATTTCTTTTT CAAGAAATTC GATGTAGGCA TCGGCGCGGC TTTTGTCTTT


 


451
GGTGATGATT TTGTTGCAGC CGCAGTAGTA GCAGATGGTG TTGCAGAACG


 


501
GAATGTGAAT GTAAAGGGAA AGCGGTTTGT TTAA






This corresponds to the amino acid sequence <SEQ ID 786; ORF 221.a>:










a221.pep




1
MVVLMLRSLV RQAVNQIDAD GFEPRFARRI DDFFGFFVTL DAVDRRLHFG



 


51
VEILNADAHA VEAESAEHED GVAADFARVD FDGVFAGGD* LEMFAYHAED


 


101
TFDLVVAQKG RRAAAEVQLG KLVPSVQMWS EQFHFFFKKF DVGIGAAFVF


 


151
GDDFVAAAVV ADGVAERNVN VKGKRFV*






m221/a221 95.5% identity in 177 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 787>:










g223.seq




1
atggaattca ggcaccaggt agtggtagtt ggtgtcgaac catttggtca



 


51
tttcgatggc gaattggtct ttgttgccgc gcgccagttg gaagaattgt


 


101
tccaaaggca ggttttggct atcgaagccg aaacgggcgg gaatcgcgcc


 


151
cgtggatact tgcaggtcga ggatgtgatg gtagaaagtg aaatcacgta


 


201
cagcaacgta atcagcgtta ggagcagctt ggtgtttcca gtttttctcg


 


251
cgcaggtctt tggcaacgtc gagcagctct tgttcactga tctctttgcg


 


301
ccagtatttt tcttgggcga atttcaattc acggaaggcg ccgacacgcg


 


351
ggaagcctga






This corresponds to the amino acid sequence <SEQ ID 788; ORF 223.ng>:










g223.pep..




1
MEFRHQVVVV GVEPFGHFDG ELVFVAARQL EELFQRQVLA IEAETGGNRA


 


51
RGYLQVEDVM VESEITYSNV ISVRSSLVFP VFLAQVFGNV EQLLFTDLFA


 


101
PVFFLGEFQF TEGADTREA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 789>:










m223.seq




1
GTGGAATTCA GGCACCAAGT AGTGGTAGTT GGTGTCGAAC CATTTGGTCA


 


51
TTTCGATAGC GAATTGGTCT TTGTTACCGC GCGCCAGTTG GAAGAATTGT


 


101
TCCAAAGACA GGTTTTGGCT GTCGAAGCCG AAGCGGGCGG GAATCGCGCC


 


151
GGTGGCGACT TGCAGGTCGA GGATGTGGTC GTAGAAAGTG AAATCsCTAC


 


201
GGCAACGAAA TCGGCGTTGG CAGCGACCTG GTGTTTCCAG TTTTTCTCGC


 


251
GCAAGTCTTT AGCAACAGCC AGCAATTCTT GCTCGCTGAT TTCTTTGCGC


 


301
CAGTATTTTT CTTGTGCGAA TTTCAATTCG CGGAAGGCGC CGACACGCGG


 


351
GAAGCCTGA






This corresponds to the amino acid sequence <SEQ ID 790; ORF 223>:










m223.pep




1
VEFRHQVVVV GVEPFGHFDS ELVFVTARQL EELFQRQVLA VEAEAGGNRA


 


51
GGDLQVEDVV VESEIXYGNE IGVGSDLVFP VFLAQVFSNS QQFLLADFFA


 


101
PVFFLCEFQF AEGADTREA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 223 shows 80.7% identity over a 119 aa overlap with a predicted ORF (ORF 223.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 791>:










a223.seq




1
GTGGAATTCA GGCACCAAGT AGTGGTAGTT GGTGTCGAAC CATTTGGTCA


 


51
TTTCGATAGC GAATTGGTCT TTGTTACCGC GCGCCAGTTG GAAGAATTGT


 


101
TCCAAAGATA GGTTTTGGCT GTCGAAGCCG AAGCGGGCGG GAATCGCGCC


 


151
GGTGGCGACT TGCAGGTCGA GGATGTGGTC GTAGAAAGTG AAATCGCCTA


 


201
CGGCAACGTA ATCGGCGTTG GCAGCGGCCT GGTGTTTCCA GTTTTTCTCG


 


251
CGCAAGTCTT TAGCAACAGC CAGCAATTCT TGCTCGCTGA TTTCTTTGCG


 


301
CCAGTATTTT TCTTGTGCGA ATTTCAATTC GCGGAAGGCA CCGACACGCG


 


351
GGAAGCCTGA






This corresponds to the amino acid sequence <SEQ ID 792; ORF 223.a>:










a223.pep




1
VEFRHQVVVV GVEPFGHFDS ELVFVTARQL EELFQR*VLA VEAEAGGNRA


 


51
GGDLQVEDVV VESEIAYGNV IGVGSGLVFP VFLAQVFSNS QQFLLADFFA


 


101
PVFFLCEFQF AEGTDTREA*






m223/a223 95.8% identity in 119 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 793>:










g225.seq




1
atggattctt ttttcaaacc ggcagtttgg gcggttttgt ggctgatgtt


 


51
tgccgtccgc cccgcccttg ccgacgagtt gaccaacctg ctcagcagcc


 


101
gcgagcagat tctcagacag tttgccgaag acgaacagcc cgttttaccc


 


151
gtcaaccgag cccccgcccg gcgggcgggc aatgccgacg aactcatcgg


 


201
cggcgcgatg gggcttaacg aacagcccgt tgtacgcgtc aaccgagccn


 


251
ccgcccggcg ggcgggcaat gccgacaaac tcatcggcag cgcgatgcgg


 


301
cttttgggta ttgcctaccg ctacggcggc acatcggtgt ctaccggttt


 


351
tgactgcagc ggattcatgc agcacatctt caaacgcgcc atgggcatca


 


401
acctgccgcg cacgtcggcg gaacaggcgc ggatgggcgc acccgttgcc


 


451
cgaagcgaat tgcagcccgg ggatatggtg tttttccgca cgctcggcgg


 


501
cagccgcatt tcccatgtcg gactttatat cggcaacaac cgcttcatcc


 


551
acgcgccgcg cacggggaaa aatatcgaaa tcaccagcct gagccacaaa


 


601
tattggagcg gcaaatatgc gttcgcccgc cgggtcaaga aaaacgaccc


 


651
gtcacgcttt ctgaactga






This corresponds to the amino acid sequence <SEQ ID 794; ORF 225.ng>:










g225.pep




1
MDSFFKPAVW AVLWLMFAVR PALADELTNL LSSREQILRQ FAEDEQPVLP


 


51
VNRAPARRAG NADELIGGAM GLNEQPVVRV NRAXARRAGN ADKLIGSAMR


 


101
LLGIAYRYGG TSVSTGFDCS GFMQHIFKRA MGINLPRTSA EQARMGAPVA


 


151
RSELQPGDMV FFRTLGGSRI SHVGLYIGNN RFIHAPRTGK NIEITSLSHK


 


201
YWSGKYAFAR RVKKNDPSRF LN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 795>:









m225.seq (partial)










1
..TTTTCAAACC CGGCAGTTTG GGCGGTTTTG TGGCTGAwGT TTGCCGTCCG



 


51
  CCCCGCCCTT GCCGACGAGT TGACCAACCT GCTCAGCAGC CGCGAGCAGA


 


101
  TTCTCAGACA GTTTGCCGAA GACGAACAGC CCGTTTTACC CATCAACCGA


 


151
  GCCCCCGCCC GGCGGGCGGG CAATGCCGAC GAACTCATCG GCAGCGCGAT


 


201
  GGGGCTTAAC GAACAGCCCG TTTTACCCGT CAACCGAGTC CCCGCCCGGC


 


251
  GGGCGGGCAA TGCCGACGAA CTCATCGGCA ACGCGATGGG GCTTAACGAA


 


301
  CAGCCCGTTT TACCCGTCAA CCGAGCCCCC GCCCGGCGGG CGGGCAATGC


 


351
  CGACGAACTC ATCGGCAACG CGATGGGACT TTTGGGTATT GCCTACCGCT


 


401
  ACGGCGGCAC ATCGGTTTCT ACCGGTTTTG ACTGCAGCGG CTTCATGCAG


 


451
  CACATCTTCA AACGCGCCAT GGGCATCAAC CTGCCGCGCA CGTCGGCAGA


 


501
  ACAGGCACGG ATGGGTACGC CGGTTGCCCG AAGCGAATTG CAGCCCGGAG


 


551
  ATATGGTGTT TTTCCGCACG CTCGGCGGCA GCCGCATTTC CCATGTCGGA


 


601
  CTTTATATCG GCAACAACCG CTTCATCCAC GCGCCGCGCA CGGGGAAAAA


 


651
  TATCGAAATC ACCAGCCTGA GCCACAAATA TTGGAGCGGC AAATACGCGT


 


701
  TCGCCCGCCG GGTCAAGAAA AACGACCCGT CCCGCTTTCT GAACTGA






This corresponds to the amino acid sequence <SEQ ID 796; ORF 225>:









m225.pep (partial)










1
..FSNPAVWAVL WLXFAVRPAL ADELTNLLSS REQILRQFAE DEQPVLPINR



 


51
  APARRAGNAD ELIGSAMGLN EQPVLPVNRV PARRAGNADE LIGNAMGLNE


 


101
  QPVLPVNRAP ARRAGNADEL IGNAMGLLGI AYRYGGTSVS TGFDCSGFMQ


 


151
  HIFKRAMGIN LPRTSAEQAR MGTPVARSEL QPGDMVFFRT LGGSRISHVG


 


201
  LYIGNNRFIH APRTGKNIEI TSLSHKYWSG KYAFARRVKK NDPSRFLN*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 225 shows 83.5% identity over a 248 aa overlap with a predicted ORF (ORF 225.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 797>:










a225.seq




1
ATGGATTCTT TTTTCAAACC GGCAGTTTGG GCGGTTTTGT GGCTGATGTT


 


51
TGCCGTCCGC CCCGCCCTTG CCGACGAGTT GACCAACCTG CTCAGCAGCC


 


101
GCGAGCAGAT TCTCAGACAG TTTGCCGAAG ACGAACAGCC CGTTTTACCC


 


151
ATCAACCGAN CCCCCGCCCG GCGGGCGGGC AATGCCGACG AACTCATCGG


 


201
CAGCGCGATG GGGCTTAACG AACAGCCCGT TTTACCCGTC AACCGANTCC


 


251
CCGCCCGGCG GGCGGGCAAT GCCGACNAAC TCATCGGCAA CGCGATGGGG


 


301
CTTAACGAAC AGCCCGTTTT ACCCGTCAAC CGAGTCCCCG CCCGGCGGGC


 


351
GGGCAATGCC GACGAACTCA TCGGCAACGC GATGGGGCTT AACGAACAGC


 


401
CCGTTTTACC CGTCAACCGA GCCCCCGCCC GGCGGGCGGG CAATGCCGAC


 


451
GAACTCATCG GCAACGCGAT GGGACTTTTG GGTATTGCCT ACCGCTACGG


 


501
CGGCACATCG ATTTCTACCG GTTTTGACTG CAGCGGCTTC ATGCAGCACA


 


551
TCTTCAAACG CGCCATGGGC ATCAACCTGC CGCGCACGTC GGCAGAACAG


 


601
GCGCGGATGG GTACGCCGGT TGCCCGAAGC GAATTGCAGC CCGGGGATAT


 


651
GGTGTNTTTC CGCACGCTCG GCGGCAGCCG CATTTCCCAT GTCGGACTTT


 


701
ATATCGGCAA CAACCGCTTC ATCCACGCGC CGCGCACGGG GAAAAATATC


 


751
GAAATCACCA GCCTGAGCCA CAAATATTGG AGCGGCAAAT ACGCGTTCGC


 


801
CCGCCGGGTC AAGAAAAACG ACCCGTCCCG CTTTCTGAAC TGA






This corresponds to the amino acid sequence <SEQ ID 798; ORF 225.a>:










a225.pep




1
MDSFFKPAVW AVLWLMFAVR PALADELTNL LSSREQILRQ FAEDEQPVLP


 


51
INRXPARRAG NADELIGSAM GLNEQPVLPV NRXPARRAGN ADXLIGNAMG


 


101
LNEQPVLPVN RVPARRAGNA DELIGNAMGL NEQPVLPVNR APARRAGNAD


 


151
ELIGNAMGLL GIAYRYGGTS ISTGFDCSGF MQHIFKRAMG INLPRTSAEQ


 


201
ARMGTPVARS ELQPGDMVXF RTLGGSRISH VGLYIGNNRF IHAPRTGKNI


 


251
EITSLSHKYW SGKYAFARRV KKNDPSRFLN *






m225/a225 87.4% identity in 277 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 799>:










g225-1.seq




1
atggattctt ttttcaaacc ggcagtttgg gcggttttgt ggctgatgtt


 


51
tgccgtccgc cccgcccttg ccgacgagtt gaccaacctg ctcagcagcc


 


101
gcgagcagat tctcagacag tttgccgaag acgaacagcc cgttttaccc


 


151
gtcaaccgag cccccgcccg gcgggcgggc aatgccgacg aactcatcgg


 


201
cggcgcgatg gggcttaacg aacagcccgt tgtacgcgtc aaccgagccn


 


251
ccgcccggcg ggcgggcaat gccgacaaac tcatcggcag cgcgatgcgg


 


301
cttttgggta ttgcctaccg ctacggcggc acatcggtgt ctaccggttt


 


351
tgactgcagc ggattcatgc agcacatctt caaacgcgcc atgggcatca


 


401
acctgccgcg cacgtcggcg gaacaggcgc ggatgggcgc acccgttgcc


 


451
cgaagcgaat tgcagcccgg ggatatggtg tttttccgca cgctcggcgg


 


501
cagccgcatt tcccatgtcg gactttatat cggcaacaac cgcttcatcc


 


551
acgcgccgcg cacggggaaa aatatcgaaa tcaccagcct gagccacaaa


 


601
tattggagcg gcaaatatgc gttcgcccgc cgggtcaaga aaaacgaccc


 


651
gtcacgcttt ctgaactga






This corresponds to the amino acid sequence <SEQ ID 800; ORF 225-1.ng>:










g225-1.pep




1
MDSFFKPAVW AVLWLMFAVR PALADELTNL LSSREQILRQ FAEDEQPVLP


 


51
VNRAPARRAG NADELIGGAM GLNEQPVVRV NRAXARRAGN ADKLIGSAMR


 


101
LLGIAYRYGG TSVSTGFDCS GFMQHIFKRA MGINLPRTSA EQARMGAPVA


 


151
RSELQPGDMV FFRTLGGSRI SHVGLYIGNN RFIHAPRTGK NIEITSLSHK


 


201
YWSGKYAFAR RVKKNDPSRF LN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 801>:










m225-1.seq




1
ATGGATTCTT TTTTCAAACC GGCAGTTTGG GCGGTTTTGT GGCTGATGTT


 


51
TGCCGTCCGC CCCGCCCTTG CCGACGAGTT GACCAACyTG CTCAGCAGCC


 


101
GCGAGCAGAT TCTCAGACAG TTTGCCGAAG ACGAACAGCC CGTTTTACCC


 


151
ATCAACCGAG CCCCCGCCCG GCGGGCGGGC AATGCCGACG AACTCATCGG


 


201
CAGCGCGATG GGGCTTAACG AACAGCCCGT TTTACCCGTC AACCGAGTCC


 


251
CCGCCCGGCG GGCGGGCAAT GCCGACGAAC TCATCGGCAA CGCGATGGGG


 


301
CTTAACGAAC AGCCCGTTTT ACCCGTCAAC CGAGCCCCCG CCCGGCGGGC


 


351
GGGCAATGCC GACGAACTCA TCGGCAACGC GATGGGACTT TTGGGTATTG


 


401
CCTACCGCTA CGGCGGCACA TCGGTTTCTA CCGGTTTTGA CTGCAGCGGC


 


451
TTCATGCAGC ACATCTTCAA ACGCGCCATG GGCATCAACC TGCCGCGCAC


 


501
GTCGGCAGAA CAGGCACGGA TGGGTACGCC GGTTGCCCGA AGCGAATTGC


 


551
AGCCCGGAGA TATGGTGTTT TTCCGCACGC TCGGCGGCAG CCGCATTTCC


 


601
CATGTCGGAC TTTATATCGG CAACAACCGC TTCATCCACG CGCCGCGCAC


 


651
GGGGAAAAAT ATCGAAATCA CCAGCCTGAG CCACAAATAT TGGAGCGGCA


 


701
AATACGCGTT CGCCCGCCGG GTCAAGAAAA ACGACCCGTC CCGCTTTCTG


 


751
AACTGA






This corresponds to the amino acid sequence <SEQ ID 802; ORF 217>:










m225-1.pep




1
MDSFFKPAVW AVLWLMFAVR PALADELTNL LSSREQILRQ FAEDEQPVLP


 


51
INRAPARRAG NADELIGSAM GLNEQPVLPV NRVPARRAGN ADELIGNAMG


 


101
LNEQPVLPVN RAPARRAGNA DELIGNAMGL LGIAYRYGGT SVSTGFDCSG


 


151
FMQHIFKRAM GINLPRTSAE QARMGTPVAR SELQPGDMVF FRTLGGSRIS


 


201
HVGLYIGNNR FIHAPRTGKN IEITSLSHKY WSGKYAFARR VKKNDPSRFL


 


251
N*






m225-1/g225-1 84.9% identity in 251 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 803>:










a225-1.seq




1
ATGGATTCTT TTTTCAAACC GGCAGTTTGG GCGGTTTTGT GGCTGATGTT


 


51
TGCCGTCCGC CCCGCCCTTG CCGACGAGTT GACCAACCTG CTCAGCAGCC


 


101
GCGAGCAGAT TCTCAGACAG TTTGCCGAAG ACGAACAGCC CGTTTTACCC


 


151
ATCAACCGAN CCCCCGCCCG GCGGGCGGGC AATGCCGACG AACTCATCGG


 


201
CAGCGCGATG GGGCTTAACG AACAGCCCGT TTTACCCGTC AACCGANTCC


 


251
CCGCCCGGCG GGCGGGCAAT GCCGACNAAC TCATCGGCAA CGCGATGGGG


 


301
CTTAACGAAC AGCCCGTTTT ACCCGTCAAC CGAGTCCCCG CCCGGCGGGC


 


351
GGGCAATGCC GACGAACTCA TCGGCAACGC GATGGGGCTT AACGAACAGC


 


401
CCGTTTTACC CGTCAACCGA GCCCCCGCCC GGCGGGCGGG CAATGCCGAC


 


451
GAACTCATCG GCAACGCGAT GGGACTTTTG GGTATTGCCT ACCGCTACGG


 


501
CGGCACATCG ATTTCTACCG GTTTTGACTG CAGCGGCTTC ATGCAGCACA


 


551
TCTTCAAACG CGCCATGGGC ATCAACCTGC CGCGCACGTC GGCAGAACAG


 


601
GCGCGGATGG GTACGCCGGT TGCCCGAAGC GAATTGCAGC CCGGGGATAT


 


651
GGTGTNTTTC CGCACGCTCG GCGGCAGCCG CATTTCCCAT GTCGGACTTT


 


701
ATATCGGCAA CAACCGCTTC ATCCACGCGC CGCGCACGGG GAAAAATATC


 


751
GAAATCACCA GCCTGAGCCA CAAATATTGG AGCGGCAAAT ACGCGTTCGC


 


801
CCGCCGGGTC AAGAAAAACG ACCCGTCCCG CTTTCTGAAC TGA






This corresponds to the amino acid sequence <SEQ ID 804; ORF 225-1.a>:










a225-1.pep




1
MDSFFKPAVW AVLWLMFAVR PALADELTNL LSSREQILRQ FAEDEQPVLP


 


51
INRXPARRAG NADELIGSAM GLNEQPVLPV NRXPARRAGN ADXLIGNAMG


 


101
LNEQPVLPVN RVPARRAGNA DELIGNAMGL NEQPVLPVNR APARRAGNAD


 


151
ELIGNAMGLL GIAYRYGGTS ISTGFDCSGF MQHIFKRAMG INLPRTSAEQ


 


201
ARMGTPVARS ELQPGDMVXF RTLGGSRISH VGLYIGNNRF IHAPRTGKNI


 


251
EITSLSHKYW SGKYAFARRV KKNDPSRFLN *






a225-1/m225-1 88.6% identity in 280 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 805>:










g226.seq




1
ATGAGCGAAA TCCTCAGGCA GCCCAGCGTT CTGCTTTTCC TCACGCTTGC


 


51
CGTGTACGCG CTTGCGATTA TCGTGCGCAC GCGCACGGGC AATATCTTCT


 


101
GCAACCCCGT ACTCGTCAGC ACTATCGTGC TGATTGCCTA CCTGAAAATC


 


151
CTCGGTATCG ATTATGCGGT GTACCACAAC GCCGCGCAAT TCATTGATTT


 


201
TCGGCTGAAA cccGccgtCG TCGTGCTTGC CGTGCCGCTC TACCAAAACC


 


251
GCCGTAAAAT CTTCAACCAG TGGCTGCCCG TCATCGTTTC GCAGCTTGCG


 


301
GGCAGCGTTA cggGCATTGT tacggggATG TATTTTgccg cttggctcgg


 


351
gccggatacc caattctcct tcccgcctcg tcttcaatat ctgttattta


 


401
caccctctgg aatcccaatt cacaccctgt atgcgcgggt tctcccgcca


 


451
tttctgttgc ctccgcctct cctgccgcgc ctcggcccgc atacattgcg


 


501
ccggttcaca atacttccaa aaaaactacg gccgtttaag cccctcctcc


 


551
cagttgtggt cctttctcct Ccgggcctcg cccctcccct cttataa






This corresponds to the amino acid sequence <SEQ ID 806; ORF 226.ng>:










g226.pep




1
MSEILRQPSV LLFLTLAVYA LAIIVRTRTG NIFCNPVLVS TIVLIAYLKI


 


51
LGIDYAVYHN AAQFIDFRLK PAVVVLAVPL YQNRRKIFNQ WLPVIVSQLA


 


101
GSVTGIVTGM YFAAWLGPDT QFSFPPRLQY LLFTPSGIPI HTLYARVLPP


 


151
FLLPPPLLPR LGPHTLRRFT ILPKKLRPFK PLLPVVVLSP PGLAPPLL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 807>:










m226.seq




1
ATGAACGAAA TCCTCAGGCA GCCCAGCGTT CTGCTTTTCC TCACGCTTGC


 


51
CGTGTACGCG CTTGCGATTA TCGtGCGCAC GCGCACGGGC AATATCTTCT


 


101
GCAACCCCGT ACTCGTCAGC ACTATCGTGC TGATTGCCTA CCTGAAAATC


 


151
CTCGGTATCG ATTATGCGGT GTACCACAAC GCCGCGCAAT TCATTGATTT


 


201
TTGGCTGAAA CCCGCCGTCG TCGTGCTTGC CGTGCCGCTC TACCAAAACC


 


251
GCCGTAAAAT CTTCAACCAG TGGCTGCCCG TCATCGTTTC ACAGCTTGCG


 


301
GGCAGCGTTA CGGGCATTGT TACAGGGATG TATTTTGCCA AATGGCTGGG


 


351
CGCGGAACGC GAAGTCGTCC TCTCGCTCGC GTCCAAATCT GTTACCAACC


 


401
CCATCGCTAT TGAAATCACC CGCTCCATCG GCGGCATTCC CGCCATTACC


 


451
GCCGCCACCG TCATCATTGC CGGTCTGGTC GGACAGATTG CCGGTTACAA


 


501
AATGCTGAAG AACACGGTCG TCATGCCCTC GTCCGTGGGT ATGTCGCTCG


 


551
GCACGGCTTC GCACGCGATG GGGATTGCCG CCTCGCTCGA ACGCAGCCGC


 


601
CGTATGGCGG CATACGCGGG GCTGGGGCTG ACGTTCAACG GCGTACTGAC


 


651
CGCGCTGATT GCGCCGCTGC TCATCCCCGT TTTGGGATTT TGA






This corresponds to the amino acid sequence <SEQ ID 808; ORF 226>:










m226.pep




1
MNEILRQPSV LLFLTLAVYA LAIIVRTRTG NIFCNPVLVS TIVLIAYLKI


 


51
LGIDYAVYHN AAQFIDFWLK PAVVVLAVPL YQNRRKIFNQ WLPVIVSQLA


 


101
GSVTGIVTGM YFAKWLGAER EVVLSLASKS VTNPIAIEIT RSIGGIPAIT


 


151
AATVIIAGLV GQIAGYKMLK NTVVMPSSVG MSLGTASHAM GIAASLERSR


 


201
RMAAYAGLGL TFNGVLTALI APLLIPVLGF *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 226 shows 94.2% identity over a 121 aa overlap with a predicted ORF (ORF 226.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 809>:










a226.seq




1
ATGAACGAAA TCCTCAGGCA GCCGAGCATC CTGCTTTTCC TCACGCTTGC


 


51
CGTGTACGCG CTTGCGATTA TCGTGCGCAC GCGCACGGGT AATATCTTCT


 


101
GCAACCCCGT ACTCGTCAGC ACTATCGTGC TGATTGCCTA CCTGAAAATC


 


151
CTCGGTATCG ATTATGCGGT GTACCACAAC GCCGCGCAGT TTATCGATTT


 


201
CTGGCTCAAG CCCGCCGTCG TCGTGCTTGC CGTGCCGCTC TACCAAAACC


 


251
GCCGTAAAAT CTTCAACCAA TGGCTGCCCG TCATCGTTTC GCAGCTTGCG


 


301
GGCAGCGTTA CGGGCATTGT TACGGGGATG TATTTTGCCA AATGGCTGGG


 


351
CGCGGAACGC GAAGTCGTCC TCTCGCTCGC GTCCAAATCT GTTACCAATC


 


401
CTATCGCCAT CGAAATCACC CGCTCCATCG GCGGCATTCC CGCCATTACC


 


451
GCCGCCACCG TCATCATTGC CGGCCTGGTC GGACAGATTG CCGGTTACAA


 


501
AATGTTGAAA AACACGGTCG TTATGCCCTC ATCTGTCGGA ATGTCGCTCG


 


551
GCACGGCTTC GCACGCGATG GGCATTGCCG CCTCGCTCGA ACGCAGCCGC


 


601
CGCATGGCGG CATACGCGGG GCTGGGGCTG ACGTTCAACG GCGTACTGAC


 


651
CGCGCTGATT GCGCCGCTGC TTATCCCCGT TTTGGGATTT TGA






This corresponds to the amino acid sequence <SEQ ID 810; ORF 226.a>:










a226.pep




1
MNEILRQPSI LLFLTLAVYA LAIIVRTRTG NIFCNPVLVS TIVLIAYLKI


 


51
LGIDYAVYHN AAQFIDFWLK PAVVVLAVPL YQNRRKIFNQ WLPVIVSQLA


 


101
GSVTGIVTGM YFAKWLGAER EVVLSLASKS VTNPIAIEIT RSIGGIPAIT


 


151
AATVIIAGLV GQIAGYKMLK NTVVMPSSVG MSLGTASHAM GIAASLERSR


 


201
RMAAYAGLGL TFNGVLTALI APLLIPVLGF *






m226/a226 99.6% identity in 230 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 811>:










g227.seq




1
atgaacatca tccgcgcgct cctcatcatc ctcggctgcc tcgccgccgg


 


51
cgaaaccgcc gttttcctag caggcatcaa actgcccggc agcatcgtcg


 


101
gcatgggcgt gctgtttgcg cttttgcagg cgggttggct caaaacgtct


 


151
tggctgcaac agcttaccga cgcgctgatg gcaaacctga cgctgttcct


 


201
cgtgccgccc tgcgtggcgg tcatcagcta tttggatttg attgccgacg


 


251
attggttttc gatactggtt tccgcctccg ccagcacttt gtgcgtactg


 


301
ctggttacgg gcaaggttca ccgctggata cggagcatta tctga






This corresponds to the amino acid sequence <SEQ ID 812; ORF 227.ng>:










g227.pep




1
MNIIRALLII LGCLAAGETA VFLAGIKLPG SIVGMGVLFA LLQAGWLKTS


 


51
WLQQLTDALM ANLTLFLVPP CVAVISYLDL IADDWFSILV SASASTLCVL


 


101
LVTGKVHRWI RSII*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 813>:









m227.seq (partial)










1
..ACGTCTTkGC TGCAACAGCT TACCGACGCG CTGATGTCGA ACCTGACGCT



 


51
  GTtCCTCGTG CCgCC.TGCG TGGCGGTCAT CAGCTATTTG GATTTGATTG


 


101
  CCGACGATTG GTTTTCGATA CTGGTTTCCG CCTCCGCCAG cACTTTGTGC


 


151
  GTACTGCTGG TTACGGGCAA AGTCCACCGG TGGATACGGG GTATTATCCG


 


201
  ATGA






This corresponds to the amino acid sequence <SEQ ID 814; ORF 227>:









m227.pep (partial)









1
..TSXLQQLTDA LMSNLTLFLV PPCVAVISYL DLIADDWFSI LVSASASTLC


 


51
  VLLVTGKVHR WIRGIIR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 227 shows 95.5% identity over a 66 aa overlap with a predicted ORF (ORF 227.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 815>:










a227.seq




1
ATGAACATCA TCCGCGCGCT CCTCATCATC CTCGGCTGCC TCGCCACCGG


 


51
CGAAACCGCC GTTTTCCTAG CAGGCATCAA ACTGCCCGGC AGCATCGTCG


 


101
GCATGGGCGT ACTGTTTGCG CTTTTGCAGG CGGGTTGGGT CAAAACGTCT


 


151
TGGCTGCAAC AGCTTACCGA CGCGCTGATG GCGAATCTGA CGTTGTTTCT


 


201
CGTGCCGCCC TGCGTGGCGG TCATCAGCTA TTTGGATTTG ATTGCCGACG


 


251
ATTGGTTTTC GATACTGGTT TCCGCCTCCG CCAGCACTTT GTGCGTACTG


 


301
CTGGTTACAG GCAAGGTTCA CCGCTGGATA CGGAGCATTA TCTGA






This corresponds to the amino acid sequence <SEQ ID 816; ORF 227.a>:










a227.pep




1
MNIIRALLII LGCLATGETA VFLAGIKLPG SIVGMGVLFA LLQAGWVKTS


 


51
WLQQLTDALM ANLTLFLVPP CVAVISYLDL IADDWFSILV SASASTLCVL


 


101
LVTGKVHRWI RSII*






m227/a227 95.5% identity in 66 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 817>:










m228.seq




1
ATGAAAAAAT TATTGATTGC CGCAATGATG GCGGCTGCCT TGGCAGCTTG


 


51
TTCGCAAGAA GCCAAACAGG AGGTTAAGGA AGCGGTTCAA GCCGTTGAGT


 


101
CCGATGTTAA AGACACTGCG GCTTCTGCCG CCGAGTCTGC CGCTTCTGCC


 


151
GTCGAAGAAG CGAAAGACCA AGTCAAAGAT GCTGCGGCTG ATGCAAAGGC


 


201
AAGTGCCGAG GAAGCTGTAA CTGAAGCCAA AGAAGCTGTA ACTGAAGCAG


 


251
CTAAAGATAC TTTGAACAAA GCTGCCGACG CGACTCAGGA AGCGGCAGAC


 


301
AAAATGAAAG ATGCCGCCAA ATAA






This corresponds to the amino acid sequence <SEQ ID 818; ORF 228>:










m228.pep




1
MKKLLIAAMM AAALAACSQE AKQEVKEAVQ AVESDVKDTA ASAAESAASA


 


51
VEEAKDQVKD AAADAKASAE EAVTEAKEAV TEAAKDTLNK AADATQEAAD


 


101
KMKDAAK*






Computer analysis of this amino acid sequence gave the following results:

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 819>:










a228.seq




1
ATGAAAAAAT TATTGATTGC CGCAATGATG GCGGCTGCCT TGGCAGCTTG


 


51
TTCGCAAGAA GCCAAACAGG AGGTTAAGGA AGCGGTTCAA GCCGTTGAGT


 


101
CCGATGTTAA AGACACTGCG GCTTCTGCCG CCGAGTCTGC CGCTTCTGCC


 


151
GTCGAAGAAG CGAAAGACCA AGTCAAAGAT GCTGCGGCTG ATGCAAAGGC


 


201
AAGTGCCGAG GAAGCTGTAA CTGAAGCCAA AGAAGCTGTA ACTGAAGCAG


 


251
CTAAAGATAC TTTGAACAAA GCTGCCGACG CGACTCAGGA AGCGGCAGAC


 


301
AAAATGAAAG ATGCCGCCAA ATAA






This corresponds to the amino acid sequence <SEQ ID 820; ORF 228.a>:










a228.pep




1
MKKLLIAAMM AAALAACSQE AKQEVKEAVQ AVESDVKDTA ASAAESAASA


 


51
VEEAKDQVKD AAADAKASAE EAVTEAKEAV TEAAKDTLNK AADATQEAAD


 


101
KMKDAAK*






m228/a228 100.0% identity in 107 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 821>:










g229.seq




1
atggctgccg tatcgggcgg cggtgcggtc ttcctgataa tgcttccaca


 


51
tattgcccgc gttcagcgtc agccgccagc gttcgcccaa gcgtcgggag


 


101
aaatcggcat tgaagccgcc ggcgaaattg tatcggctgc cgcccaagag


 


151
gttttgcccg acaaacggca cggtgccgaa cgagcgcgtt accgaacggt


 


201
tttgatggcc gaacgacagg cgcaggttct gttcgctgaa atctttgtta


 


251
tcccaataat gcacgccgcg gctgatgccg ccgtagagga aatgatgccc


 


301
gcccgcattg atttcgcgcg acacgcccaa gccgtagcgc aaaccgtgtg


 


351
ccttttgcgg caggctgtcg gcggttttcg tccagcttct gcccgcaaat


 


401
tcaatcgttt tttcggacga agcgttgttt atagcggatt aacaaaaatc


 


451
aggacaaggc ggcgggccgc aggcagtacg gatggtacgg aaccggttcg


 


501
cccggtgctt ggacgcctta gggaaccgtt ccctttgagc cggggcgggg


 


551
caacccgtac cggtttttgt tcatccgcca tattgtgttg a






This corresponds to the amino acid sequence <SEQ ID 822; ORF 229.ng>:










g229.pep




1
MAAVSGGGAV FLIMLPHIAR VQRQPPAFAQ ASGEIGIEAA GEIVSAAAQE


 


51
VLPDKRHGAE RARYRTVLMA ERQAQVLFAE IFVIPIMHAA ADAAVEEMMP


 


101
ARIDFARHAQ AVAQTVCLLR QAVGGFRPAS ARKFNRFFGR SVVYSGLTKI


 


151
RTRRRAAGST DGTEPVRPVL GRLREPFPLS RGGATRTGFC SSAILC*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 823>:









m229.seq (partial)










1
..GCTCAAGCGT TGGGAGAAAT CGGCATTGAA GCCGCCGACG AAATTGTATC



 


51
  GGCTGCCGCC TAAGAGGTTT TGCTCGACAA ACGGCACGAT GCCGAACGAG


 


101
  CGCGTTACCG AACGGTTTTT ATAGCCGAAC GACAGGCGCA GGCTCTGTTC


 


151
  GCTGAAATCT TTGTTATCCC AATAATGCAC GCCGCCGCCG CTGATGCCGC


 


201
  CGTAGAGGAA ATGATGCCTG CCCGCATTGA TTTCGCGCGA CACGCCTAAG


 


251
  CCCTAGCGCA AACCGTGTGC CTTTTGCGGC AGGCTGTCGG CGGTTTTCGT


 


301
  CCAGCTTCTG CCCGCAAATT CAATCGTTTT TTCGGACGAA GCGTTGTTTA


 


351
  TAGCGGATTA ACAAAAATCA GGACAAGGCA ACGAAGCCGC AGACAGTACA


 


401
  AATAGTACGG AACCGATTCA CTTGGTGCTT CAGCACcTTA GAGAATCGTT


 


451
  CTCTTTTTTG TTCATCCGCT ATATTGTGTT GA






This corresponds to the amino acid sequence <SEQ ID 824; ORF 229>:









m229.pep (partial)










1
..AQALGEIGIE AADEIVSAAA XEVLLDKRHD AERARYRTVF IAERQAQALF



 


51
  AEIFVIPIMH AAAADAAVEE MMPARIDFAR HAXALAQTVC LLRQAVGGFR


 


101
  PASARKFNRF FGRSVVYSGL TKIRTRQRSA DSTNSTEPIH LVLQHLRESR


 


151
  SLFCSSAILC *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 229 shows 80.5% identity over a 169 aa overlap with a predicted ORF (ORF 229.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 825>:









a229.seq (partial)










1
ATGGCTGTCG TATCGGGCGG CGGTGCGGTC TTCCTGATAA CGCTTCCACA



 


51
TATTGCCCAC GTTCAGCGTC AGCCGCCA.. GTTCGCTCAA GCGTCGGGAG


 


101
AAATCGGCAT TGAAGCCGCC GACGAAATTG TATCGGCTGC CGCCTAAGAG


 


151
GTTTTGCTCG ATAAACGGCA CGATGCCGAA TGAGCGCGTT ACTGAACGGT


 


201
TTTTATAGCC GAGCGACAGG CGCAGGCTCT GTTCGCTGAA ATCTTTGTTA


 


251
TCCTAATAGT GCACGCCGCC GCCGCTGATG TCTCCGTAGA GGAAATGATG


 


301
CCCGCCCGCA TTGATTTCGC GCGACACGCC CAAGCCGTAG CGCAAACCGT


 


351
GTGCCTTTTG CGGCAGGCTG TCGGCGGTTT TCGTCCAGCT TCTGCCTGCA


 


401
AATTCAATCG TTTTTTCGGA CGAAGCGTTG TTTATAGCGG ATTAACAAAA


 


451
ATCAGGACAA GGCGACGAAG CGCAGACAGT ACAGATAGTA CGGAACCGAT


 


501
TCACTTGGTG CTTCAGCACC TTAGAGAATC GTCTCTTTGA GCTAAGGCGA


 


551
GGCAACGCCG TACTGGTTTT TGTTCATCCA CTATA






This corresponds to the amino acid sequence <SEQ ID 826; ORF 229.a>:









a229.pep (partial)









1
MAVVSGGGAV FLITLPHIAH VQRQPPXFAQ ASGEIGIEAA DEIVSAAA*E


 


51
VLLDKRHDAE *ARY*TVFIA ERQAQALFAE IFVILIVHAA AADVSVEEMM


 


101
PARIDFARHA QAVAQTVCLL RQAVGGFRPA SACKFNRFFG RSVVYSGLTK


 


151
IRTRRRSADS TDSTEPIHLV LQHLRESSL* AKARQRRTGF CSSTI






m229/a229 85.6% identity in 167 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 827>:










g230.seq




1
atgttccatt ccatcgaaaa atacagaaca cccgcccaag tcttattagg


 


51
cctgattgca ttaacttttg tcggcttcgg cgtcagcacg gtttcccatc


 


101
cgggcgccga ctacatcgtc caagtgggcg acgaaaaaat cagcgagcac


 


151
tcaatcaaca acgccatgca gaacgagcag gcggacggcg gcagcccttg


 


201
gcgcgacgcg gtgttccaat ccctgctgca acgcgcctac ctgaaacagg


 


251
gcgcgaagct gatgggcatt tcggtttctt ccgaacaaat caagcagatg


 


301
attgtggacg atcccaattt ccacgacgca aacggcaaat tcagtcacgc


 


351
gcttttgagt caatacctgt cgcaacgcca tatgtctgaa gaccagtttg


 


401
tcgaagaaat ccgcgatcag tttgccttgc agaatttggt aagcctcgtc


 


451
caaaacggcg tattggtcgg cgacgcgcag gcggaacagc tgatcaggct


 


501
gacgcaggtc aaccgcacca tccgttcgca cactttcaac cccgacgagt


 


551
tcatcgccca agtcaaagcg tctgaagccg atttgcagaa attttataat


 


601
gcgaacaaaa aagactatct gctgccgcag gcggtcaaat tggaatatgt


 


651
cgccttgaat ctgaaggatt ttgcagacaa gcagaccgtc agtgaaacgg


 


701
aagtgaaaaa tgcgtttgaa gagcgcgtgg cgcgtttgcc ggcacatgaa


 


751
gccaaacctt ctttcgagca ggaaaaagcc gccgtcgaaa acgaattgaa


 


801
aatgaaaaag gcggttgccg acttcaacaa ggcaaaagaa aagctgggcg


 


851
acgatgcgtt caatcatccc tcctcgcttg ccgaagccgc caaaaacagc


 


901
ggtttgaaag tggaaaccca agaaacttgg ctgagcaggc aggacgcaca


 


951
aatgtccggc atgcccgaaa acctaatcaa tgccgtattc agcgacgacg


 


1001
tattgaagaa aaaacacaat tccgaagtgc tgaccatcaa cagcgaaacc


 


1051
gcgtgggtcg tccgcgccaa agaagtccgc gaagaaaaaa acctactgtt


 


1101
tgaagaagcc aaagatgcgg tgcgtcaggc ctatatccgt accgaagccg


 


1151
ccaaactttt gaaaacaatg taa






This corresponds to the amino acid sequence <SEQ ID 828; ORF 230.ng>:










g230.pep




1
MFHSIEKYRT PAQVLLGLIA LTFVGFGVST VSHPGADYIV QVGDEKISEH


 


51
SINNAMQNEQ ADGGSPWRDA VFQSLLQRAY LKQGAKLMGI SVSSEQIKQM


 


101
IVDDPNFHDA NGKFSHALLS QYLSQRHMSE DQFVEEIRDQ FALQNLVSLV


 


151
QNGVLVGDAQ AEQLIRLTQV NRTIRSHTFN PDEFIAQVKA SEADLQKFYN


 


201
ANKKDYLLPQ AVKLEYVALN LKDFADKQTV SETEVKNAFE ERVARLPAHE


 


251
AKPSFEQEKA AVENELKMKK AVADFNKAKE KLGDDAFNHP SSLAEAAKNS


 


301
GLKVETQETW LSRQDAQMSG MPENLINAVF SDDVLKKKHN SEVLTINSET


 


351
AWVVRAKEVR EEKNLLFEEA KDAVRQAYIR TEAAKLLKTM *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 829>:









m230.seq (partial)










1
ATGTTCCATT CCATCGAAAA ATACAGAACG CCCGCCCAAG TCCTTTTGGG



 


51
CCTGATTGCA TTAACCTTCG TCGGCTTCGG GGTCAGCACG GTATCCCATC


 


101
CGGGTGCCGA CTACATCGTC CAAGTGGGCG ACGAAAAAaT CAGCGACCAC


 


151
TCCATCAACA ACGCCATACA GAACGAACAG GCGGACGGCG GCGGCCCTTC


 


201
GCc.GACGCG GTGTTCCAAT CCCTGCTGCA ACGCGCCTAC CTGAAACAGG


 


251
GCGCGAAGCT GATGGGCATT TCGGTTTCTT CCGAACAAAT CAAGCAAATT


 


301
ATCGTGGACG ATCCCAATTT CCACGACGCA AACGGCAAAT TCGACCACGC


 


351
GCTTTTAAAC CGCTACCTTT CCCAACGCCA TATGTCTGAA GACCAGTTTG


 


401
TCGAAGAAAT CCGCGATCAG TTTGCCTTGC AGAATTTGGT AAACCTCGTC


 


451
CAAAACGGCG TATTGGTCGG CGACGCGCAG GCGGAACAGC TGATCAGGCT


 


501
GACACAGGTC AACCGCACCA TCCGTTCGCA CACTTTCAAC CCCGACGAGT


 


551
TCATCGCCCA AGTCAAAGTG TCTGAAGCCG ATTTGCAGAA ATTTTATAAT


 


601
GCGAACAAAA AAGACTATCT GCTGCCGCAG gCGGTCAAAT TGGAATATGT


 


651
CGCCTTGAAT CTGAAGGATT TTGCAGACAA GCAGACCGTC AGTGAAACGg


 


701
AAGTGAAAAA TGCATTTGAA GAGCGCGTGG CGCGTTTGCC GGCAAATGAA


 


751
GCCAAACCTT CTTTCGAGCA GGAAAAAGCC GCCGTCGAAA ACGAATTGAA


 


801
AATGAAAAAG GCGGTTGCCG ACTTCAACAA GGCAAAAGAA AAATTGGGCG


 


851
ACGATGC.GT cAACCATCCT TCyTCGCTTG CCGAAGCCGC CAAAAACAGC


 


901
GGTTTGAAAG TCGAAACCCA AGAAACTTGG CTGAGTAGGC AGGACGCGCA


 


951
AATGTCCGGT ATGCCCGAAA ACCTGATCAA TGCCGTATTC AGCGACGACG


 


1001
TATTGAAGAA AAAACACAAT TCCGAAGTGC TGACCATCAA CAGCGAAACC


 


1051
GCGTGGGTCG TCCGCGCCAA AGAAGTCCGC GAAGAGAAAA CCCTGCCGTT


 


1101
TGCCGAAGCC AAAGACGCGG TACGTCAGGC TTATATCCGT ACCGAAGCCG


 


1151
CCAAACTT.. ...






This corresponds to the amino acid sequence <SEQ ID 830; ORF 230>:









m230.pep (partial)










1
MFHSIEKYRT PAQVLLGLIA LTFVGFGVST VSHPGADYIV QVGDEKISDH



 


51
SINNAIQNEQ ADGGGPSPDA VFQSLLQRAY LKQGAKLMGI SVSSEQIKQI


 


101
IVDDPNFHDA NGKFDHALLN RYLSQRHMSE DQFVEEIRDQ FALQNLVNLV


 


151
QNGVLVGDAQ AEQLIRLTQV NRTIRSHTFN PDEFIAQVKV SEADLQKFYN


 


201
ANKKDYLLPQ AVKLEYVALN LKDFADKQTV SETEVKNAFE ERVARLPANE


 


251
AKPSFEQEKA AVENELKMKK AVADFNKAKE KLGDDAVNHP SSLAEAAKNS


 


301
GLKVETQETW LSRQDAQMSG MPENLINAVF SDDVLKKKHN SEVLTINSET


 


351
AWVVRAKEVR EEKTLPFAEA KDAVRQAYIR TEAAKL....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 230 shows 95.9% identity over a 386 aa overlap with a predicted ORF (ORF 230.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 831>:









a230.seq (partial)










1
ATGTTCCATT CCATCGAAAA ATACAGAACG CCCGCCCAAG TCCTTTTGGG



 


51
CCTGATTGCA TTAACCTTCG TCGGCTTCGG GGTCAGCACG GTATCCCATC


 


101
CGGGTGCCGA CTACATCGTC CAAGTGGGCG ACGAAAAAAT CAGCGACCAC


 


151
TCCATCAACA ACGCCATACA GAACGAACAG GCGGACGGCG GCGGCCCTTC


 


201
GCGCGACGCG GTGTTCCAAT CCCTGCTACA ACGCGCCTAC CTGAAACAGG


 


251
GCGCGAAGCT GATGGGCATT TCGGTTTCTT CCGAACAAAT CAAGCAGATT


 


301
ATCGTGGACG ATCCCAATTT CCACGACGCA AACGGCAAAT TCGACCACGC


 


351
GCTTTTAAAC CGCTACCTTT CCCAACGTCA TATGTCTGAA GACCAGTTTG


 


401
TCGAAGAAAT CCGCGATCAG TTTGCCTTGC AGAATTTGGT AAACCTCGTC


 


451
CAAAACGGCG TATTGGTCGG CGACGCGCAG GCGGAACAGC TGATCAGGCT


 


501
GACGCAGGTC AACCGCACCA TCCGTTCGCA CACTTTCAAC CCCGACGAAT


 


551
TCATCGCCCA AGTCAAAGTG TCTGAAGCCG ATTTGCAGAA GTTTTATAAC


 


601
GCAAACAAAA AAGACTACCT GCTTCCCAAA GCGGTCAAAT TGGAATATGT


 


651
CGCCTTGAAT CTGAAAGACT TTGCAGACAA ACAGACCGTC AGCGAAACAG


 


701
AAGTGAAAAA TGCGTTTGAA GAGCGCGTGG CGCGTTTGCC GGCAAATGAA


 


751
GCCAAACCTT CTTTCGAGCA GGAAAAAGCC GCCGTCGAAA ACGAATTGAA


 


801
AATGAAAAAG GCGGTTGCCG ACTTCAATAA GGCAAAAGAA AAGCTGGGCG


 


851
ATGACGCGTT CAACCATCCT TCCTCGCTTG CCGAAGCCGC CAAAAACAGC


 


901
GGTTTGAAAG TCGAAACCCA AGAAACTTGG CTGAGCAGGC AGGATGCGCA


 


951
AATGTCCGGT ATGCCCGAAA ACCTGATCAA TGCCGTATTC AGCGACGACG


 


1001
TATTGAAGAA AAAACACAAT TCCGAAGTGC TGACCATCAA CAGCGAAACC


 


1051
GCGTGGGTCG TCCGCGCCAA AGAAGTCCGC GAAGAGAAAA CCCTGCCGTT


 


1101
TGCCGAAGCC AAAGACGCGG TACGTCAGGC TTATATCCGT ACCGAAGCCG


 


1151
CCAAACTT






This corresponds to the amino acid sequence <SEQ ID 832; ORF 230.a>:









a230.pep (partial)










1
MFHSIEKYRT PAQVLLGLIA LTFVGFGVST VSHPGADYIV QVGDEKISDH



 


51
SINNAIQNEQ ADGGGPSRDA VFQSLLQRAY LKQGAKLMGI SVSSEQIKQI


 


101
IVDDPNFHDA NGKFDHALLN RYLSQRHMSE DQFVEEIRDQ FALQNLVNLV


 


151
QNGVLVGDAQ AEQLIRLTQV NRTIRSHTFN PDEFIAQVKV SEADLQKFYN


 


201
ANKKDYLLPK AVKLEYVALN LKDFADKQTV SETEVKNAFE ERVARLPANE


 


251
AKPSFEQEKA AVENELKMKK AVADFNKAKE KLGDDAFNHP SSLAEAAKNS


 


301
GLKVETQETW LSRQDAQMSG MPENLINAVF SDDVLKKKHN SEVLTINSET


 


351
AWVVRAKEVR EEKTLPFAEA KDAVRQAYIR TEAAKL






m230/a230 99.2% identity in 386 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 833>:










g230-1.seq




1
ATGTTCCATT CCATCGAAAA ATACAGAACA CCCGCCCAAG TCTTATTAGG


 


51
CCTGATTGCA TTAACTTTTG TCGGCTTCGG CGTCAGCACG GTTTCCCATC


 


101
CGGGCGCCGA CTACATCGTC CAAGTGGGCG ACGAAAAAAT CAGCGAGCAC


 


151
TCAATCAACA ACGCCATGCA GAACGAGCAG GCGGACGGCG GCAGCCCTTG


 


201
GCGCGACGCG GTGTTCCAAT CCCTGCTGCA ACGCGCCTAC CTGAAACAGG


 


251
GCGCGAAGCT GATGGGCATT TCGGTTTCTT CCGAACAAAT CAAGCAGATG


 


301
ATTGTGGACG ATCCCAATTT CCACGACGCA AACGGCAAAT TCAGTCACGC


 


351
GCTTTTGAGT CAATACCTGT CGCAACGCCA TATGTCTGAA GACCAGTTTG


 


401
TCGAAGAAAT CCGCGATCAG TTTGCCTTGC AGAATTTGGT AAGCCTCGTC


 


451
CAAAACGGCG TATTGGTCGG CGACGCGCAG GCGGAACAGC TGATCAGGCT


 


501
GACGCAGGTC AACCGCACCA TCCGTTCGCA CACTTTCAAC CCCGACGAGT


 


551
TCATCGCCCA AGTCAAAGCG TCTGAAGCCG ATTTGCAGAA ATTTTATAAT


 


601
GCGAACAAAA AAGACTATCT GCTGCCGCAG GCGGTCAAAT TGGAATATGT


 


651
CGCCTTGAAT CTGAAGGATT TTGCAGACAA GCAGACCGTC AGTGAAACGG


 


701
AAGTGAAAAA TGCGTTTGAA GAGCGCGTGG CGCGTTTGCC GGCACATGAA


 


751
GCCAAACCTT CTTTCGAGCA GGAAAAAGCC GCCGTCGAAA ACGAATTGAA


 


801
AATGAAAAAG GCGGTTGCCG ACTTCAACAA GGCAAAAGAA AAGCTGGGCG


 


851
ACGATGCGTT CAATCATCCC TCCTCGCTTG CCGAAGCCGC CAAAAACAGC


 


901
GGTTTGAAAG TGGAAACCCA AGAAACTTGG CTGAGCAGGC AGGACGCACA


 


951
AATGTCCGGC ATGCCCGAAA ACCTAATCAA TGCCGTATTC AGCGACGACG


 


1001
TATTGAAGAA AAAACACAAT TCCGAAGTGC TGACCATCAA CAGCGAAACC


 


1051
GCGTGGGTCG TCCGCGCCAA AGAAGTCCGC GAAGAAAAAA ACCTACTGTT


 


1101
TGAAGAAGCC AAAGATGCGG TGCGTCAGGC CTATATCCGT ACCGAAGCCG


 


1151
CCAAACTTGC CGAAAACAAG GCAAAAGAAG TGCTTACCCA ACTGAACGGC


 


1201
GGCAAGGCAG TTGACGTGAA ATGGTCGGAA GTGTCCGTTT TGGGCGCGCA


 


1251
GCAGGCAAGG CAGTCCATGC CGCCCGAGGC TTATGCGGAA CTGCTGAAAG


 


1301
CAAAACCGGC AAACGGCAAA CCCGCCTATG TCAGACTGAC CGGTCTGCCG


 


1351
GCACCCGTGA TTGTCGAGGC GCAGGCAGTC ACGCCTCCGG AGGATATTGC


 


1401
CGCACAGCTT CCTCCTGCGA AACAGGCTTT GGCGCAACAG CAGTCTGCCA


 


1451
ATACTTTCGA CCTGCTGATC CGCTATTTCA ACGGAAAAAT CAAACAGACT


 


1501
AAAGGAGCAC AATCGGTTGA CAACGGCGAT GGTCAGTAA






This corresponds to the amino acid sequence <SEQ ID 834; ORF 230-1.ng>:










g230-1.pep




1
MFHSIEKYRT PAQVLLGLIA LTFVGFGVST VSHPGADYIV QVGDEKISEH


 


51
SINNAMQNEQ ADGGSPWRDA VFQSLLQRAY LKQGAKLMGI SVSSEQIKQM


 


101
IVDDPNFHDA NGKFSHALLS QYLSQRHMSE DQFVEEIRDQ FALQNLVSLV


 


151
QNGVLVGDAQ AEQLIRLTQV NRTIRSHTFN PDEFIAQVKA SEADLQKFYN


 


201
ANKKDYLLPQ AVKLEYVALN LKDFADKQTV SETEVKNAFE ERVARLPAHE


 


251
AKPSFEQEKA AVENELKMKK AVADFNKAKE KLGDDAFNHP SSLAEAAKNS


 


301
GLKVETQETW LSRQDAQMSG MPENLINAVF SDDVLKKKHN SEVLTINSET


 


351
AWVVRAKEVR EEKNLLFEEA KDAVRQAYIR TEAAKLAENK AKEVLTQLNG


 


401
GKAVDVKWSE VSVLGAQQAR QSMPPEAYAE LLKAKPANGK PAYVRLTGLP


 


451
APVIVEAQAV TPPEDIAAQL PPAKQALAQQ QSANTFDLLI RYFNGKIKQT


 


501
KGAQSVDNGD GQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 835>:










m230-1.seq




1
ATGTTCCATT CCATCGAAAA ATACAGAACG CCCGCCCAAG TCCTTTTGGG


 


51
CCTGATTGCA TTAACCTTCG TCGGCTTCGG GGTCAGCACG GTATCCCATC


 


101
CGGGTGCCGA CTACATCGTC CAAGTGGGCG ACGAAAAAAT CAGCGACCAC


 


151
TCCATCAACA ACGCCATACA GAACGAACAG GCGGACGGCG GCGGCCCTTC


 


201
GCGCGACGCG GTGTTCCAAT CCCTGCTGCA ACGCGCCTAC CTGAAACAGG


 


251
GCGCGAAGCT GATGGGCATT TCGGTTTCTT CCGAACAAAT CAAGCAAATT


 


301
ATCGTGGACG ATCCCAATTT CCACGACGCA AACGGCAAAT TCGACCACGC


 


351
GCTTTTAAAC CGCTACCTTT CCCAACGCCA TATGTCTGAA GACCAGTTTG


 


401
TCGAAGAAAT CCGCGATCAG TTTGCCTTGC AGAATTTGGT AAACCTCGTC


 


451
CAAAACGGCG TATTGGTCGG CGACGCGCAG GCGGAACAGC TGATCAGGCT


 


501
GACACAGGTC AACCGCACCA TCCGTTCGCA CACTTTCAAC CCCGACGAGT


 


551
TCATCGCCCA AGTCAAAGTG TCTGAAGCCG ATTTGCAGAA ATTTTATAAT


 


601
GCGAACAAAA AAGACTATCT GCTGCCGCAG GCGGTCAAAT TGGAATATGT


 


651
CGCCTTGAAT CTGAAGGATT TTGCAGACAA GCAGACCGTC AGTGAAACGG


 


701
AAGTGAAAAA TGCATTTGAA GAGCGCGTGG CGCGTTTGCC GGCAAATGAA


 


751
GCCAAACCTT CTTTCGAGCA GGAAAAAGCC GCCGTCGAAA ACGAATTGAA


 


801
AATGAAAAAG GCGGTTGCCG ACTTCAACAA GGCAAAAGAA AAATTGGGCG


 


851
ACGATGCGTT CAACCATCCT TCCTCGCTTG CCGAAGCCGC CAAAAACAGC


 


901
GGTTTGAAAG TCGAAACCCA AGAAACTTGG CTGAGTAGGC AGGACGCGCA


 


951
AATGTCCGGT ATGCCCGAAA ACCTGATCAA TGCCGTATTC AGCGACGACG


 


1001
TATTGAAGAA AAAACACAAT TCCGAAGTGC TGACCATCAA CAGCGAAACC


 


1051
GCGTGGGTCG TCCGCGCCAA AGAAGTCCGC GAAGAGAAAA CCCTGCCGTT


 


1101
TGCCGAAGCC AAAGACGCGG TACGTCAGGC TTATATCCGT ACCGAAGCCG


 


1151
CCAAACTTGC CGAAAACAAG GCAAAAGACG TGCTTACCCA ACTGAACGGC


 


1201
GGCAAGGCTG TTGACGTGAA ATGGTCGGAA GTGTCCGTTT TGGGCGCACA


 


1251
GCAGGCAAGG CAGTCCATGC CGCCCGAGGC TTATGCGGAA CTGCTGAAAG


 


1301
CAAAACCGGC AAACGGCAAA CCCGCCTACG TCAGGCTGAT CGGTCTGCCG


 


1351
GCACCCGTGA TTGTCGAAGT ACAGGCTGTA ACCCCGCCGG ATGATATCGC


 


1401
CGCACAGCTT CCGCTTGCAA AACAGGCTTT GGCGCAACAG CAGTCTGCCA


 


1451
ATACTTTCGA CTTGTTGATA CGTTATTTCA ACGGCAAAAT CAAACAGACC


 


1501
AAAGGAGCGC AATCGGTCGA CAACGGCGAC GGTCAGTAA






This corresponds to the amino acid sequence <SEQ ID 836; ORF 230-1>:










m230-1.pep




1
MFHSIEKYRT PAQVLLGLIA LTFVGFGVST VSHPGADYIV QVGDEKISDH


 


51
SINNAIQNEQ ADGGGPSRDA VFQSLLQRAY LKQGAKLMGI SVSSEQIKQI


 


101
IVDDPNFHDA NGKFDHALLN RYLSQRHMSE DQFVEEIRDQ FALQNLVNLV


 


151
QNGVLVGDAQ AEQLIRLTQV NRTIRSHTFN PDEFIAQVKV SEADLQKFYN


 


201
ANKKDYLLPQ AVKLEYVALN LKDFADKQTV SETEVKNAFE ERVARLPANE


 


251
AKPSFEQEKA AVENELKMKK AVADFNKAKE KLGDDAFNHP SSLAEAAKNS


 


301
GLKVETQETW LSRQDAQMSG MPENLINAVF SDDVLKKKHN SEVLTINSET


 


351
AWVVRAKEVR EEKTLPFAEA KDAVRQAYIR TEAAKLAENK AKDVLTQLNG


 


401
GKAVDVKWSE VSVLGAQQAR QSMPPEAYAE LLKAKPANGK PAYVRLIGLP


 


451
APVIVEVQAV TPPDDIAAQL PLAKQALAQQ QSANTFDLLI RYFNGKIKQT


 


501
KGAQSVDNGD GQ*






m230-1/g230-1 96.3% identity in 512 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 837>:










a230-1.seq




1
ATGTTCCATT CCATCGAAAA ATACAGAACG CCCGCCCAAG TCCTTTTGGG


 


51
CCTGATTGCA TTAACCTTCG TCGGCTTCGG GGTCAGCACG GTATCCCATC


 


101
CGGGTGCCGA CTACATCGTC CAAGTGGGCG ACGAAAAAAT CAGCGACCAC


 


151
TCCATCAACA ACGCCATACA GAACGAACAG GCGGACGGCG GCGGCCCTTC


 


201
GCGCGACGCG GTGTTCCAAT CCCTGCTACA ACGCGCCTAC CTGAAACAGG


 


251
GCGCGAAGCT GATGGGCATT TCGGTTTCTT CCGAACAAAT CAAGCAGATT


 


301
ATCGTGGACG ATCCCAATTT CCACGACGCA AACGGCAAAT TCGACCACGC


 


351
GCTTTTAAAC CGCTACCTTT CCCAACGTCA TATGTCTGAA GACCAGTTTG


 


401
TCGAAGAAAT CCGCGATCAG TTTGCCTTGC AGAATTTGGT AAACCTCGTC


 


451
CAAAACGGCG TATTGGTCGG CGACGCGCAG GCGGAACAGC TGATCAGGCT


 


501
GACGCAGGTC AACCGCACCA TCCGTTCGCA CACTTTCAAC CCCGACGAAT


 


551
TCATCGCCCA AGTCAAAGTG TCTGAAGCCG ATTTGCAGAA GTTTTATAAC


 


601
GCAAACAAAA AAGACTACCT GCTTCCCAAA GCGGTCAAAT TGGAATATGT


 


651
CGCCTTGAAT CTGAAAGACT TTGCAGACAA ACAGACCGTC AGCGAAACAG


 


701
AAGTGAAAAA TGCGTTTGAA GAGCGCGTGG CGCGTTTGCC GGCAAATGAA


 


751
GCCAAACCTT CTTTCGAGCA GGAAAAAGCC GCCGTCGAAA ACGAATTGAA


 


801
AATGAAAAAG GCGGTTGCCG ACTTCAATAA GGCAAAAGAA AAGCTGGGCG


 


851
ATGACGCGTT CAACCATCCT TCCTCGCTTG CCGAAGCCGC CAAAAACAGC


 


901
GGTTTGAAAG TCGAAACCCA AGAAACTTGG CTGAGCAGGC AGGATGCGCA


 


951
AATGTCCGGT ATGCCCGAAA ACCTGATCAA TGCCGTATTC AGCGACGACG


 


1001
TATTGAAGAA AAAACACAAT TCCGAAGTGC TGACCATCAA CAGCGAAACC


 


1051
GCGTGGGTCG TCCGCGCCAA AGAAGTCCGC GAAGAGAAAA CCCTGCCGTT


 


1101
TGCCGAAGCC AAAGACGCGG TACGTCAGGC TTATATCCGT ACCGAAGCCG


 


1151
CCAAACTTGC CGAAAACAAG GCAAAAGACG TGCTTACCCA ACTGAACGGC


 


1201
GGCAAGGCTG TTGACGTGAA ATGGTCGGAA GTGTCCGTTT TGGGCGCACA


 


1251
GCAGGCAAGG CAGTCCATGC CGCCCGAGGC TTATGCGGAA CTGCTGAAAG


 


1301
CAAAACCGGC AAACGGCAAA CCCGCCTACG TCAGGCTGAT CGGTCTGCCG


 


1351
GCACCCGTGA TTGTCGAAGT ACAGGCTGTA ACCCCGCCGG ATGATATCGC


 


1401
CGCACAGCTT CCGCTTGCAA AACAGGCTTT GGCGCAACAG CAGTCTGCCA


 


1451
ATACTTTCGA CTTGTTGATA CGTTATTTCA ACGGCAAAAT CAAACAGACC


 


1501
AAAGGAGCGC AATCGGTCGA CAACGGCGAC GGTCAGTAA






This corresponds to the amino acid sequence <SEQ ID 838; ORF 230-1.a>:










a230-1.pep




1
MFHSIEKYRT PAQVLLGLIA LTFVGFGVST VSHPGADYIV QVGDEKISDH


 


51
SINNAIQNEQ ADGGGPSRDA VFQSLLQRAY LKQGAKLMGI SVSSEQIKQI


 


101
IVDDPNFHDA NGKFDHALLN RYLSQRHMSE DQFVEEIRDQ FALQNLVNLV


 


151
QNGVLVGDAQ AEQLIRLTQV NRTIRSHTFN PDEFIAQVKV SEADLQKFYN


 


201
ANKKDYLLPK AVKLEYVALN LKDFADKQTV SETEVKNAFE ERVARLPANE


 


251
AKPSFEQEKA AVENELKMKK AVADFNKAKE KLGDDAFNHP SSLAEAAKNS


 


301
GLKVETQETW LSRQDAQMSG MPENLINAVF SDDVLKKKHN SEVLTINSET


 


351
AWVVRAKEVR EEKTLPFAEA KDAVRQAYIR TEAAKLAENK AKDVLTQLNG


 


401
GKAVDVKWSE VSVLGAQQAR QSMPPEAYAE LLKAKPANGK PAYVRLIGLP


 


451
APVIVEVQAV TPPDDIAAQL PLAKQALAQQ QSANTFDLLI RYFNGKIKQT


 


501
KGAQSVDNGD GQ*






a230-1/m230-1 99.8% identity in 512 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 839>:










g231.seq




1
atgtcaaaac gaaaatccat aaaccgtccg tatcaaaaac cggcggaact


 


51
gccgccgttg caaaataatc cgccatttta ccgtaaaaac cgccgcctga


 


101
acttttttat cgcggcagac ggcggttgcg cgtctccgca aaaatgcagg


 


151
gcgcgcggtt ttcagacggc atttgccgtt caaggccgtg cggtgtcttt


 


201
accaaatgcc caaccattcg cccacggaat ccatccaatc cttattgccc


 


251
ccgccgctcc tgcctgcccg gcggtacgcc cacggcgctt gcggattttt


 


301
agctttccac aatcctttgc gttccctttc cgcctgaatt tgagcgtcgg


 


351
catagtcggc aaaatccgcc ttatcctgct gttctttagc ataactttta


 


401
taatgccacg ccgccccgtc ctgcacctgc atcaggttca aatcggtttt


 


451
gccggcggat acctgcgcca cttcgcgctg atagcggtcg gtttcaaaca


 


501
cacgtacact gactttccta ccctccgccg ccgcgcgcag gttgtcgcgc


 


551
gaacgtgtac cgtaagcctg tttcatctcc ggtgcgtcga tatacgccat


 


601
ccgaatttta tgtttcgcgc cgtcgccgtc gatgacgtga agggtatcgc


 


651
cgtcatagac tttggacacc gtgcctgtgt agctgtggcc ggatttcgcc


 


701
gatgcccgtc ggcgaacggg cgcgtcgaaa cccacgtccc ctgcagtgcc


 


751
gagtacgtcg agtacggcaa ccgccgtccg caccgcctca ctgtcatatc


 


801
ccgtataacc caacgcgccc aaaagcgaca gggcgacggg aagccatttc


 


851
atgatttttt taatctgcat atttttcaaa tgccgatgcc gtctgaacat


 


901
ctctga






This corresponds to the amino acid sequence <SEQ ID 840; ORF 231.ng>:










g231.pep




1
MSKRKSINRP YQKPAELPPL QNNPPFYRKN RRLNFFIAAD GGCASPQKCR


 


51
ARGFQTAFAV QGRAVSLPNA QPFAHGIHPI LIAPAAPACP AVRPRRLRIF


 


101
SFPQSFAFPF RLNLSVGIVG KIRLILLFFS ITFIMPRRPV LHLHQVQIGF


 


151
AGGYLRHFAL IAVGFKHTYT DFPTLRRRAQ VVARTCTVSL FHLRCVDIRH


 


201
PNFMFRAVAV DDVKGIAVID FGHRACVAVA GFRRCPSANG RVETHVPCSA


 


251
EYVEYGNRRP HRLTVISRIT QRAQKRQGDG KPFHDFFNLH IFQMPMPSEH


 


301
L*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 841>:









m231.seq (partial)










1
ATGTCAAAAC GAAAATCCAT AAACCGTCCG TATCAAAAAC CGGCGGAACT



 


51
GCCGCCGTTG CAAAATAATC CGCCATTTTA CCGTAAAAAC CGCCGCCTGA


 


101
ACTTTTTTAT CGCGGCAGAC GGCGGTTGCG CGTCTCCGCA AAAATGCAGG


 


151
GCGCGCGGTT TTCAGACGGC ATTTGCCGTT CAAAGCCGTG CGGTGTCTTT


 


201
ACCAAATGCC CAACCATTCG GC....






This corresponds to the amino acid sequence <SEQ ID 842; ORF 231>:









m231.pep (partial)










1
MSKRKSINRP YQKPAELPPL QNNPPFYRKN RRLNFFIAAD GGCASPQKCR



 


51
ARGFQTAFAV QSRAVSLPNA QPFG.....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 231 shows 98.6% identity over a 73 aa overlap with a predicted ORF (ORF 231.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 843>:









a231.seq (partial)










1
ATGTCAAAAC GAAAATCCAT AAACCGTCCG TATCAAAAAC CGGCGGAACT



 


51
GCCGCCGTTG CAAAATAATC CGCCATTTTA CCGTAAAAAC CGCCGCCTGA


 


101
ACTTTTTTAT CGNGGCAGAC GGCGGTTGCG CGTCTCCGCA AAAATGCAGG


 


151
GCGCGCGGTT TTCAGACGGC ATTTGCCGTT CAAAGCCGTG CGGTGTCTTT


 


201
ACCAAATGCC CAACCATTCG CCCACGGCAT CCATCCAATC CTTATTGCCC


 


251
CCGCCGCTCC TGCCTGCCCG GCGGTACGCC CACGGCGCTT GCGGATTTTT


 


301
AGCTTTCCAC AATCCTTTGC GTTCCCTTTC CGCCTGAATT TGAGCGTCGG


 


351
CATAATCGGC AAAATCCGCC TTATCCTGCT GTTCTTTAGC ATAACTTTTA


 


401
TAATGCCACG CCGCCCCGTC CTGCACCTGC ATCAGGTTCA AATCGGTTTT


 


451
GCCGACAGAA ACCTGCGCCA CTTCGCGCTG GTAGCGGTCG GTGTCGAACA


 


501
CGCGGACGCT GACTTTCCTG CCTTCCGCCG CCGCGCGCAG GTTGTCGCGC


 


551
GAACGCGTGC CGTAAGCCTG TTTCATCTCC GGCGCGTCGA TATACGCCAT


 


601
CCGGATTTTG TGTTTCGCGC CGTCGCCGTC GATAACGTGA AGGGTGTCGC


 


651
CGTCATAGAC TTTGGACACC GTGCCTGTGT AGCGGTGGCC GGATTTCGCC


 


701
GATGCTCGGC GGCGGGCGGG CGCGTCGGAA CCCGCGTCCC CTGCCGCGCC


 


751
GAGTACGTCG AGTACGGCAA CCGCCGTCCG CACCGCCTCG CTGCCGTACC


 


801
CCGTATAACC CAACGCACCC AAAAGCGACA AGGCGACGGG AAGCCATTTC


 


851
ATGATTTTTT TAATCTGCAT ATTTTTCAAA TGCCGATGCC GTCTGAACAT


 


901
ATC






This corresponds to the amino acid sequence <SEQ ID 844; ORF 217.a>:









a231.pep (partial)










1
MSKRKSINRP YQKPAELPPL QNNPPFYRKN RRLNFFIXAD GGCASPQKCR



 


51
ARGFQTAFAV QSRAVSLPNA QPFAHGIHPI LIAPAAPACP AVRPRRLRIF


 


101
SFPQSFAFPF RLNLSVGIIG KIRLILLFFS ITFIMPRRPV LHLHQVQIGF


 


151
ADRNLRHFAL VAVGVEHADA DFPAFRRRAQ VVARTRAVSL FHLRRVDIRH


 


201
PDFVFRAVAV DNVKGVAVID FGHRACVAVA GFRRCSAAGG RVGTRVPCRA


 


251
EYVEYGNRRP HRLAAVPRIT QRTQKRQGDG KPFHDFFNLH IFQMPMPSEH


 


301
I






m231/a231 98.6% identity in 73 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 845>:










g231-1.seq




1
ATGTCAAAAC GAAAATCCAT AAACCGTCCG TATCAAAAAC CGGCGGAACT


 


51
GCCGCCGTTG CAAAATAATC CGCCATTTTA CCGTAAAAAC CGCCGcCTGA


 


101
ACTTTTTTAT CGCGGCAGAC GGCGGTTGCG CGTCTCCGCA AAAATGCAGG


 


151
GCGCGCGGTT TTCAGACGGC ATTTGCCGTT CAAGGCCGTG CGGTGTCTTT


 


201
ACCAAATGCC CAACCATTCG CCCACGGAAT CCATCCAATC CTTATTGCCC


 


251
CCGCCGCTCC TGCCTGCCCG GCGGTACGCC CACGGCGCTT GCGGATTTTT


 


301
AGCTTTCCAC AATCCTTTGC GTTCCCTTTC CGCCTGAATT TGAGCGTCGG


 


351
CATAGTCGGC AAAATCCGCC TTATCCTGCT GTTCTTTAGC ATAACTTTTA


 


401
TAATGCCACG CCGCCCCGTC CTGCACCTGC ATCAGGTTCA AATCGGTTTT


 


451
GCCGGCGGAT ACCTGCGCCA CTTCGCGCTG ATAGCGGTCG GTTTCAAACa


 


501
CaCgTaCaat gagtttcgtA ccctccGCCG ccgcgcgCAG GTTGtcgcGC


 


551
GAACgTGTAC CGTAagcgtg TTtcatctcc GGTGCgtcGA TATACGCCaT


 


601
cCgAATTTta tGTttcgcgc cgtcgcCgtc gATGACGTGA AGGGtatcGC


 


651
CgtcATAGAC TTTGGACACC Gtgcctgcgt AGctGTGGCC GGATttcgc






This corresponds to the amino acid sequence <SEQ ID 846; ORF 231-1.ng>:










g231-1.pep




1
MSKRKSINRP YQKPAELPPL QNNPPFYRKN RRLNFFIAAD GGCASPQKCR


 


51
ARGFQTAFAV QGRAVSLPNA QPFAHGIHPI LIAPAAPACP AVRPRRLRIF


 


101
SFPQSFAFPF RLNLSVGIVG KIRLILLFFS ITFIMPRRPV LHLHQVQIGF


 


151
AGGYLRHFAL IAVGFKHTYN EFRTLRRRAQ VVARTCTVSV FHLRCVDIRH


 


201
PNFMFRAVAV DDVKGIAVID FGHRACVAVA GFR






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 847>:










m231-1.seq




1
ATGTCAAAAC GAAAATCCAT AAACCGTCCG TATCAAAAAC CGGCGGAACT


 


51
GCCGCCGTTG CAAAATAATC CGCCATTTTA CCGTAAAAAC CGCCGCCTGA


 


101
ACTTTTTTAT CGCGGCAGAC GGCGGTTGCG CGTCTCCGCA AAAATGCAGG


 


151
GCGCGCGGTT TTCAGACGGC ATTTGCCGTT CAAAGCCGTG CGGTGTCTTT


 


201
ACCAAATGCC CAACCATTCG CCCACGGCAT CCATCCAATC CTTATTGCCC


 


251
CCGCCGCTCC TGCCTGCTCG GCGGTACGCC CACGGCGCTT GCGGATTTTT


 


301
AGCTTTCCAC AATCCTTTGC GTTCCCTTTC CGCCTGAATT TGAGCGTCGG


 


351
CATAATCGGC AAAATCCGCC TTATCCTGCT GTTCTTTAGC ATAACTTTTA


 


401
TAATGCCACG CCGCCCCGTC CTGCACCTGC ATCAGGTTCA AATCGGTTTT


 


451
GCCGACAGAA ACCTGCGCCA CTTCGCGCTG GTAGCGGTCG GTATCGAACA


 


501
CGCGCACGCT GACTTTCCTG CCTTCCGCCG CCGCGCGCAG GTTGTCGCGC


 


551
GAACGCGTGC CGTAAGCCTG TTTCATCTCC GGCGCGTCGA TATACGCCAT


 


601
CCGGATTTTG TGTTTCGCGC CGTCGCCGTC GATAACGTGA AGGGTGTCGC


 


651
CGTCATAGAC TTTGGACACC GTGCCTGTGT AGCGGTGGCC GGATTTCGCC


 


701
GATGCTCGGC GGCGGGCGGG CGCGTCGGAA CCCGCGTCCC CTGCCGCGCC


 


751
GAGTACGTCG AGTACGGCAA CCGCCGTCCG CACCGCCTCG CTGCCGTACC


 


801
CCGTATAACC CAACGCACCC AAAAGCGACA GGGCGACGGG AAGCCATTTC


 


851
ATGATTTTTT TAATCTGCAT ATTTTTCAAA TGCCGATGCC GTCTGAACAT


 


901
ATCGGAATCG GATTTCAGAC GGCATCTTAA






This corresponds to the amino acid sequence <SEQ ID 848; ORF 231-1>:










m231-1.pep




1
MSKRKSINRP YQKPAELPPL QNNPPFYRKN RRLNFFIAAD GGCASPQKCR


 


51
ARGFQTAFAV QSRAVSLPNA QPFAHGIHPI LIAPAAPACS AVRPRRLRIF


 


101
SFPQSFAFPF RLNLSVGIIG KIRLILLFFS ITFIMPRRPV LHLHQVQIGF


 


151
ADRNLRHFAL VAVGIEHAHA DFPAFRRRAQ VVARTRAVSL FHLRRVDIRH


 


201
PDFVFRAVAV DNVKGVAVID FGHRACVAVA GFRRCSAAGG RVGTRVPCRA


 


251
EYVEYGNRRP HRLAAVPRIT QRTQKRQGDG KPFHDFFNLH IFQMPMPSEH


 


301
IGIGFQTAS*






g231-1/m231-1 87.0% identity in 262 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 849>:










a231-1.seq




1
ATGTCAAAAC GAAAATCCAT AAACCGTCCG TATCAAAAAC CGGCGGAACT


 


51
GCCGCCGTTG CAAAATAATC CGCCATTTTA CCGTAAAAAC CGCCGCCTGA


 


101
ACTTTTTTAT CGCGGCAGAC GGCGGTTGCG CGTCTCCGCA AAAATGCAGG


 


151
GCGCGCGGTT TTCAGACGGC ATTTGCCGTT CAAAGCCGTG CGGTGTCTTT


 


201
ACCAAATGCC CAACCATTCG CCCACGGCAT CCATCCAATC CTTATTGCCC


 


251
CCGCCGCTCC TGCCTGCCCG GCGGTACGCC CACGGCGCTT GCGGATTTTT


 


301
AGCTTTCCAC AATCCTTTGC GTTCCCTTTC CGCCTGAATT TGAGCGTCGG


 


351
CATAATCGGC AAAATCCGCC TTATCCTGCT GTTCTTTAGC ATAACTTTTA


 


401
TAATGCCACG CCGCCCCGTC CTGCACCTGC ATCAGGTTCA AATCGGTTTT


 


451
GCCGACAGAA ACCTGCGCCA CTTCGCGCTG GTAGCGGTCG GTGTCGAACA


 


501
CGCGGACGCT GACTTTCCTG CCTTCCGCCG CCGCGCGCAG GTTGTCGCGC


 


551
GAACGCGTGC CGTAAGCCTG TTTCATCTCC GGCGCGTCGA TATACGCCAT


 


601
CCGGATTTTG TGTTTCGCGC CGTCGCCGTC GATAACGTGA AGGGTGTCGC


 


651
CGTCATAGAC TTTGGACACC GTGCCTGTGT AGCGGTGGCC GGATTTCGCC


 


701
GATGCTCGGC GGCGGGCGGG CGCGTCGGAA CCCGCGTCCC CTGCCGCGCC


 


751
GAGTACGTCG AGTACGGCAA CCGCCGTCCG CACCGCCTCG CTGCCGTACC


 


801
CCGTATAACC CAACGCACCC AAAAGCGACA AGGCGACGGG AAGCCATTTC


 


851
ATGATTTTTT TAATCTGCAT ATTTTTCAAA TGCCGATGCC GTCTGAACAT


 


901
ATCGGAATCG GATTTCAGAC GGCATCTTAA






This corresponds to the amino acid sequence <SEQ ID 850; ORF 231-1.a>:










a231-1.pep




1
MSKRKSINRP YQKPAELPPL QNNPPFYRKN RRLNFFIAAD GGCASPQKCR


 


51
ARGFQTAFAV QSRAVSLPNA QPFAHGIHPI LIAPAAPACP AVRPRRLRIF


 


101
SFPQSFAFPF RLNLSVGIIG KIRLILLFFS ITFIMPRRPV LHLHQVQIGF


 


151
ADRNLRHFAL VAVGVEHADA DFPAFRRRAQ VVARTRAVSL FHLRRVDIRH


 


201
PDFVFRAVAV DNVKGVAVID FGHRACVAVA GFRRCSAAGG RVGTRVPCRA


 


251
EYVEYGNRRP HRLAAVPRIT QRTQKRQGDG KPFHDFFNLH IFQMPMPSEH


 


301
IGIGFQTAS*






a231-1/m231-1 99.0% identity in 309 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 851>:










g232.seq




1
atgatgggca acagcctgat tgaatccggt acgtttgtcg ccatcctgtt


 


51
tggtcagatt ttgggaacgg cggttgccgg cgcgccgcct tatattgtcg


 


101
ggatactggt tttgctggtc gccgtcggag gaacggccgg cagcctgttt


 


151
atgccgtccg tacccgccaa ggctgccgat acccaaatcg agtggaatat


 


201
tgtccgtggt acaaaatccc tgctgcgtga aacggtgcgg cacaatcccg


 


251
tttttaccgc cattatcggc atctcgtggt tttggtttgt cggcgcggtt


 


301
tataccacgc aactgccgac ctttacccaa atccatttgg gcggcaacga


 


351
taatgttttt aacctgatgc ttgctttgtt ttccatcggt attgccgccg


 


401
gttcggtact gtgtgccaag ttcggcaggg aacggctgat gttggcttgg


 


451
gtaacggttg gtgcgttggg ttcgacggtt tgcggcctgg ttttggtgtg


 


501
gctgacgcac ggacaccgtt ttgaagggct gaacggcatt ttttggtttt


 


551
tatcgcaagg atgggcatac cccgtgatgg cggtgatgac gctgatcggc


 


601
tttttcggcg gatttttctc cgttccgctc tatacctggc tgcaaaccgc


 


651
cagcagcgag actttccgcg cccgcgccgt tgccgccaac aatatcgtta


 


701
acggcatctt tatggtttcc gccgccgttt tgagcgcggt attgctgttt


 


751
ttgtttgaca gcatttccct gctgtatctg attgtcgcct tgggcaatat


 


801
tccgttggcg gtatttttga ttaagcgcga aaggcggttt ttaggcgcgg


 


851
cggcaatcag gaaaaaacct tga






This corresponds to the amino acid sequence <SEQ ID 852; ORF 232.ng>:










g232.pep




1
MMGNSLIESG TFVAILFGQI LGTAVAGAPP YIVGILVLLV AVGGTAGSLF


 


51
MPSVPAKAAD TQIEWNIVRG TKSLLRETVR HNPVFTAIIG ISWFWFVGAV


 


101
YTTQLPTFTQ IHLGGNDNVF NLMLALFSIG IAAGSVLCAK FGRERLMLAW


 


151
VTVGALGSTV CGLVLVWLTH GHRFEGLNGI FWFLSQGWAY PVMAVMTLIG


 


201
FFGGFFSVPL YTWLQTASSE TFRARAVAAN NIVNGIFMVS AAVLSAVLLF


 


251
LFDSISLLYL IVALGNIPLA VFLIKRERRF LGAAAIRKKP *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 853>:










m232.seq




1
ATGATGGGCA ACAGCCTGAT TGAATCGGGT ACGTTTGTCG CCATCCTGTT


 


51
CGGTCAGATT TTGGGAACGG CGGTGGCAGG TGTACCGCCT TATATTGTCG


 


101
GGATACTGGT TTTGCTGGTC GCCGTCGGAG GCACGGTCGG CAGCCTGTTT


 


151
ATGCCGTCCG TACCCGCCAA GGCTGCCGAT ACACAAATTG AGTGGAATAT


 


201
TGTCCGTGGC ACAAAATCCC TGCTGCGTGA AACGGTGCGG CACAAGCCCG


 


251
TTTTTACCGC CATTATCGGT ATTTCGTGGT TTTGGTTTGT CGGCGCGGTT


 


301
TATACCACGC AACTGCCGAC CTTTACCCAA ATCCATCTGG GCGGCAACGA


 


351
CAATGTTTTC AACCTGATGC TTGCTCTGTT TTCCATCGGT ATTGCCGCCG


 


401
GTTCGGTACT GTGTGCCAAG TTCAGCAkGG AACGCCTGAT GTTGGCTTGG


 


451
GTAACGGTTG GTGCGTTGGG TTTGACGGTT TGCGGCTTGG TTTTGGTGTG


 


501
GCTGACGCAC GGACACCGTT TTGAAGGGCT GAACGGCATT TTTTrGTTTT


 


551
TATCGCAAGG ATGGGCATAT CCCGTGATGG CGGTGATGAC GCTGATCGGC


 


601
TTTTTCGGCG GATTTTTCTC CGTTCCGCTC TATACCt(g)TG CAAACCGCCa


 


651
TAGCGAGaTT TCCGCGCCCg GCCGTTGCCG CCAACAATAT CGTTAACGGT


 


701
ATTTTTATGG TTTCCGCTGC CGTTTTGAGC GCGGTGTTGC TGTTTTTGTT


 


751
TGACAGCATT TCCTTGTTGT ATCTGATTGT CGCTTTGGGC AATATTCCGT


 


801
TGTCGGTATT TTTGATTAAG CGCGAAAGGC GGTTTTTAGG CGCGGCGGCA


 


851
ATCAGGAAAA AACCTTGA






This corresponds to the amino acid sequence <SEQ ID 854; ORF 232>:










m232.pep




1
MMGNSLIESG TFVAILFGQI LGTAVAGVPP YIVGILVLLV AVGGTVGSLF


 


51
MPSVPAKAAD TQIEWNIVRG TKSLLRETVR HKPVFTAIIG ISWFWFVGAV


 


101
YTTQLPTFTQ IHLGGNDNVF NLMLALFSIG IAAGSVLCAK FSXERLMLAW


 


151
VTVGALGLTV CGLVLVWLTH GHRFEGLNGI FXFLSQGWAY PVMAVMTLIG


 


201
FFGGFFSVPL YTVQTAIARF PRPAVAANNI VNGIFMVSAA VLSAVLLFLF


 


251
DSISLLYLIV ALGNIPLSVF LIKRERRFLG AAAIRKKP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 232 shows 94.1% identity over a 290 aa overlap with a predicted ORF (ORF 232.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 855>:










a232.seq




1
ATGTACGCTA AAAAAGGCGG TTTGGGACTG GTTAAAAGCC GCCGTTTCGC


 


51
ACCTCTTTTC GCTACGCAGT TTCTCGGCGC GTTCAACGAC AATGTGTTCA


 


101
AAACCGCGCT GTTTGTGATG ATTGGGTTTT ACGGTTTGGG GCAAAACGGC


 


151
TTCCTGCCTG CCGGACAGAT GTTGAACTTG GGCGCGTTGC TGTTTATTTT


 


201
GCCGTATTTC CTGTTTTCCT CGCTGTCGGG GCAGTTGGGT AACAAATTCG


 


251
ACAAGGCCGT TTTGGCGCGT TGGGCCAAGG TGCTGGAAAT GATCATTATG


 


301
GCGGTGGCGG CATACGGGTT TTATATCCGG TCTGCCCCGC TGCTTTTGGC


 


351
GTGTCTGTTT TGCATGGGCG CGCAATCGAC GCTGTTCGGG CCGCTGAAAT


 


401
ACGCCATCCT GCCCGATTAT CTCGACGACA AAGAGTTGAT GATGGGCAAC


 


451
AGCCTGATTG AATCGGGTAC GTTTGTCGCC ATCCTGTTCG GTCAGATACT


 


501
GGGGACTGCG GTGGCAGGTG TACCGCCTTA TATTGTCGGG ATACTGGTTT


 


551
TGCTGGTCGC CGTAGGAGGC ACGGTCGGCA GCCTGTTTAT GCCGTCCGTA


 


601
CCCGCCAAGG CTGCCGATAC ACAAATTGAG TGGAATATTG TCCGGGGTAC


 


651
AAAATCCCTG CTGCGTGAAA CGGTGCGGCA CAAGCCCGTT TTTACCGCCA


 


701
TTATCGGTAT TTCGTGGTTT TGGTTTGTCG GCGCGGTTTA TACCACGCAA


 


751
CTGCCGACCT TTACCCAAAT CCATCTAGGC GGCAACGACA ATGTTTTCAA


 


801
CCTGATGCTT GCCCTGTTTT CCATCGGTAT TGCCGCCGGT TCGGTACTGT


 


851
GTGCCAAGTT CAGCAGGGAA CGGCTGAGGT TGGCTTGGGT AACGGTTGGT


 


901
GCGTTGGGTT TGACGGTTTG CGGCTTGGTT TTGGTGTGGC TGACGCACGG


 


951
ACACCGTTTT GAAGGGCTGA ACGGCATTTT TTGGTTTTTA TCGCAAGGAT


 


1001
GGGCATATCC CGTGATGGCG GTGATGACGC TGATCGGCTT TTTCGGCGGA


 


1051
TTTTTCTCCG TTCCGCTCTA TACCTGGCTG CAAACCGCCA GTAGCGAGAC


 


1101
TTTCCGCGCC CGCGCCGTTG CCGCCAACAA TATCGTTAAC GGTATTTTTA


 


1151
TGGTTTCCGC TGCCGTTTTG AGCGCGGTGT TGCTGTTTTT GTTTGACAGC


 


1201
ATTTCCTTGT TGTATCTGAT TGTCGCTTTG GGCAATATTC CGTTGTCGGT


 


1251
ATTTTTGATT AAGCGCGAAA GGCGGTTTTT AGGCGCGGCG GCAATCAGGA


 


1301
AAAAACCTTG A






This corresponds to the amino acid sequence <SEQ ID 856; ORF 232.a>:










a232.pep




1
MYAKKGGLGL VKSRRFAPLF ATQFLGAFND NVFKTALFVM IGFYGLGQNG


 


51
FLPAGQMLNL GALLFILPYF LFSSLSGQLG NKFDKAVLAR WAKVLEMIIM


 


101
AVAAYGFYIR SAPLLLACLF CMGAQSTLFG PLKYAILPDY LDDKELMMGN


 


151
SLIESGTFVA ILFGQILGTA VAGVPPYIVG ILVLLVAVGG TVGSLFMPSV


 


201
PAKAADTQIE WNIVRGTKSL LRETVRHKPV FTAIIGISWF WFVGAVYTTQ


 


251
LPTFTQIHLG GNDNVFNLML ALFSIGIAAG SVLCAKFSRE RLRLAWVTVG


 


301
ALGLTVCGLV LVWLTHGHRF EGLNGIFWFL SQGWAYPVMA VMTLIGFFGG


 


351
FFSVPLYTWL QTASSETFRA RAVAANNIVN GIFMVSAAVL SAVLLFLFDS


 


401
ISLLYLIVAL GNIPLSVFLI KRERRFLGAA AIRKKP*






m232/a232 95.9% identity in 290 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 857>:










g233.seq




1
atgaaacgca aaaatatcgc gctgattccc gccgccggca tcggggtgcg


 


51
tttcggtgcg gacaaaccca agcaatatgt cgaaatcgga agcaaaaccg


 


101
ttttagaaca tgtacttggg atttttgaac ggcatgaggc cgtcgatttg


 


151
accgtcgttg tcgtctcgcc cgaagacacg tttgccgata aggttcagac


 


201
ggcatttcca caggttcggg tgtggaaaaa cggtggacag acccgcgccg


 


251
aaactgtccg caacggtgtg gcaaaactgt tggaaaccgg tttggcggcg


 


301
gaaaccgaca atattctggt acacgatgcc gcccgctgct gcctgccgtc


 


351
tgaagctctg gcgcggttga tagaacaggc gggcaacgcc gccgaaggcg


 


401
ggattttggc agttcccgtt gccgatacgc tcaagcgcgc agaaagcgga


 


451
caaatcagtg caactgtcga ccgttcgggg ctttggcagg cgcaaacgcc


 


501
gcagcttttt caagcgggtt tgctgcaccg cgcattggct gcggaaaact


 


551
tgggcggcat taccgatgaa gcgtccgccg tggaaaaact gggtgtgcgt


 


601
ccgctactga tacagggcga cgcgcgcaat ttgaaactga cgcagccgca


 


651
ggacgcatac atcgtcaggc tgctgctcaa tgccgtctga






This corresponds to the amino acid sequence <SEQ ID 858; ORF 233.ng>:










g233.pep




1
MKRKNIALIP AAGIGVRFGA DKPKQYVEIG SKTVLEHVLG IFERHEAVDL


 


51
TVVVVSPEDT FADKVQTAFP QVRVWKNGGQ TRAETVRNGV AKLLETGLAA


 


101
ETDNILVHDA ARCCLPSEAL ARLIEQAGNA AEGGILAVPV ADTLKRAESG


 


151
QISATVDRSG LWQAQTPQLF QAGLLHRALA AENLGGITDE ASAVEKLGVR


 


201
PLLIQGDARN LKLTQPQDAY IVRLLLNAV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 859>:









m233.seq (partial)










1
ATGAAGCGCA AAAATATCGC GCTGATTCCC GCCGCCGGCA TCGGGGCGCG



 


51
TTTCGGTGCG GACAAACCCA AGCAATATGT CGAAATCGGA AGCAAAACCG


 


101
TTTTAGAACA TACGATTGGG ATTTTTGAAC GGCATGAGGC CGTCGATTTG


 


151
ACCGTCGTTG TCGTCTCGCC CGAAGACACG TTTGCCGATA AGGTTCAGAC


 


201
GGCATTTCCA CAGGTTCGGG TGTGGAAAAA CGGCGGACAG ACCCGCGCCG


 


251
AAACCGTCCG CAACGGTGTG GCAAAACTGT TGGAAACCGG TTTGGCGGCG


 


301
GAAACCGACA ATATTCTGGT ACACGATGCC GCGCGTTGCT GCCTGCCGTC


 


351
TGAAGCTTTG ACGCGGTTGA TAGAACAGGC GGGCAACGCC GCCGAAGGCG


 


401
GGATTTTGGC AATTCCCATT GCCGATACGC TCAAGTGCGC GGACGGTGGG


 


451
AACATT....






This corresponds to the amino acid sequence <SEQ ID 860; ORF 233>:









m233.pep (partial)










1
MKRKNIALIP AAGIGARFGA DKPKQYVEIG SKTVLEHTIG IFERHEAVDL



 


51
TVVVVSPEDT FADKVQTAFP QVRVWKNGGQ TRAETVRNGV AKLLETGLAA


 


101
ETDNILVHDA ARCCLPSEAL TRLIEQAGNA AEGGILAIPI ADTLKCADGG


 


151
NI....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 233 shows 93.4% identity over a 152 aa overlap with a predicted ORF (ORF 233.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 861>:










a233.seq




1
ATGAAGCGCA AAAATATCGC GCTGATTCCC GCCGCCGGCA TCGGGGCGCG


 


51
TTTCGGTGCG GACAAACCCA AGCAATATGT CGAAATCGGA AGCAAAACCG


 


101
TTTTAGAACA TACGATTGGG ATTTTTGAAC GGCATGAGGC CGTCGATTTG


 


151
ACCGTCGTTG TCGTCTCGCC CGAAGACACG TTTGCCGATA AGGTTCAGAC


 


201
GGCATTTCCA CAGGTTCGGG TGTGGAAAAA CGGCGGACAG ACCCGCGCCG


 


251
AAACTGTCCG CAACGGTGTG GCAAAATTGT TGGAAACCGG TTTGGCGGCG


 


301
GAAACCGACA ATATTCTGGT ACACGATGCC GCGCGTTGCT GCCTGCCGTC


 


351
TGAAGCTTTG ACGCGGTTGA TAGAACAGGC GGGCAACGCT GCCGAAGGTG


 


401
GGATTTTGGC AATTCCCGTT GCCGATACGC TCAAGTGCGC GGACGGTGGG


 


451
AACATTAGTG CAACCGTCGA GCGGACGAGC CTTTGGCAGG CGCAAACGCC


 


501
GCAGCTTTTC CGCGCCGGGC TGCTGCACCG CGCATTGGCT GCGGAAAACT


 


551
TGGACGGCAT TACCGATGAA GCGTCCGCCG TGGAAAAATT GGGCATCCGC


 


601
CCTTTGCTGG TGCAGGGCGA CGCGCGCAAT TTGAAACTGA CGCAGCCGCA


 


651
GGACGCATAC ATCGTCAGGC TGCTGCTCGA TGCCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 862; ORF 233.a>:










a233.pep




1
MKRKNIALIP AAGIGARFGA DKPKQYVEIG SKTVLEHTIG IFERHEAVDL


 


51
TVVVVSPEDT FADKVQTAFP QVRVWKNGGQ TRAETVRNGV AKLLETGLAA


 


101
ETDNILVHDA ARCCLPSEAL TRLIEQAGNA AEGGILAIPV ADTLKCADGG


 


151
NISATVERTS LWQAQTPQLF RAGLLHRALA AENLDGITDE ASAVEKLGIR


 


201
PLLVQGDARN LKLTQPQDAY IVRLLLDAV*






m233/a233 99.3% identity in 152 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 863>:










g234.seq




1
atgaaaaccg tttccgccgc catcgctttt gccgccgctg ccgtttcact


 


51
gaccggctgt gcgaccgagt cctcacgcag cctcgaggtt gcaaaagtcg


 


101
cctcctgcaa tacgcaatat cacggtgttc gcaccccgat ttccgtcgga


 


151
acattcgaca accgctccag cttccaaaaa ggcattttct ccgacagtga


 


201
agaccgtctg ggcagccagg caaaaaccat cctggtaaca cacctgcaac


 


251
aaaccaaccg cttcaacgta ctgaaccgca ccaaccttag cgcattgaaa


 


301
caggaatccg gcatttccgg caaagcgcag aacctgaaag gcgcagatta


 


351
tgtcgttacc ggcgatgtaa ccgaattcgg acgcagagat gtcggcgatc


 


401
atcagctctt cggcattttg ggtcgcggca aatcgcaaat cgcctatgca


 


451
aaagtggctc tgaatatcgt caacgtcaat acttccgaaa tcgtctattc


 


501
cacacagggc gcgggcgaat acgcactttc caaccgcgaa atcatcggtt


 


551
tcggcggcac ttccggctac gatgcgactt tgaacggcaa agttttagac


 


601
ttggcaatcc gcgaagccgt cgacaacttg gttcaggctg tcgacaacgg


 


651
cgcatggcaa tccaaccgtt aa






This corresponds to the amino acid sequence <SEQ ID 864; ORF 234.ng>:










g234.pep




1
MKTVSAAIAF AAAAVSLTGC ATESSRSLEV AKVASCNTQY HGVRTPISVG


 


51
TFDNRSSFQK GIFSDSEDRL GSQAKTILVT HLQQTNRFNV LNRTNLSALK


 


101
QESGISGKAQ NLKGADYVVT GDVTEFGRRD VGDHQLFGIL GRGKSQIAYA


 


151
KVALNIVNVN TSEIVYSTQG AGEYALSNRE IIGFGGTSGY DATLNGKVLD


 


201
LAIREAVDNL VQAVDNGAWQ SNR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 865>:









m234.seq (partial)










1
...GGCGCGGGCG AATACGCACT TTCCAACCGt GAAATCATCG GTTTCGGCGG



 


51
   CACTTCCGGC TACGATGCGA CTTTGAACGG CAAAGTTTTA GACTTGGCAA


 


101
   TCCGCGAAGC .gTCAACAGC CTGGTTCAGG CTGTTGACAA CGGCGCATGG


 


151
   CAACCCAACC GTTAA






This corresponds to the amino acid sequence <SEQ ID 866; ORF 234>:









m234.pep (partial)










1
..GAGEYALSNR EIIGFGGTSG YDATLNGKVL DLAIREAVNS LVQAVDNGAW



 


51
  QPNR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 234 shows 94.4% identity over a 54 aa overlap with a predicted ORF (ORF 234.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 867>:









a234.seq (partial)










1
AACCGCACCT ATTTGAACGC ATTAAAACAG GAATCCGGCA TTTCCGGCAA



 


51
AGCGCATAAC CTGAAAGGCG CAAATTATGT CGNNACCGGC GATGTAACCG


 


101
AATTCGGACG CANAGATGTC GGCGATCATC AGCTCTTCGG CATTTTGGGT


 


151
CGCGGCAAAT CGCAAATCGC CTATGCAAAA GTGGCTCTGA ATATCGTCAA


 


201
CGTCAATACT TCCGAAATCG TCTATTCCGC ACAGGGCGCG GGCGAATACG


 


251
CACTTTCCAA CCGTGAAATC ATCGGTTTCG GCGGCACTTC CGGCTACGAT


 


301
GCGACTTTGA ACGGCAAAGT TTTAGACTTG GCAATCCGCG AAGCCGTCAA


 


351
CAGCCTGGTT CAGGCTGTTG ACAACGGCGC ATGGCAACCC AACCGTTAA






This corresponds to the amino acid sequence <SEQ ID 868; ORF 234.a>:









a234.pep (partial)










1
NRTYLNALKQ ESGISGKAHN LKGANYVXTG DVTEFGRXDV GDHQLFGILG



 


51
RGKSQIAYAK VALNIVNVNT SEIVYSAQGA GEYALSNREI IGFGGTSGYD


 


101
ATLNGKVLDL AIREAVNSLV QAVDNGAWQP NR*






m234/a234 100.0% identity in 54 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 869>:










g235.seq




1
atgaaacctt tgattttagg gcttgccgcc gtgttggctc tgtctgcctg


 


51
ccaagttcga aaagctcccg acctcgacta cacgtcattc aaagaaagca


 


101
aaccggcttc aattttggtg gttccgccgc tgaacgagtc gcctgatgtc


 


151
aacggcactt gggggatgct ggcttcgacc gccgcgccga tttccgaagc


 


201
cggctattac gtctttcccg ccgcagtcgt ggaggaaacc ttcaaagaaa


 


251
acggcttgac caatgccgcc gatattcacg ccgtccggcc ggaaaaactg


 


301
catcaaattt tcggcaatga tgcggttttg tacattacgg ttaccgaata


 


351
cggcacttca tatcaaattt tagacagcgt gacgaccgta tccgccaaag


 


401
cacggctggt cgattcccgc aacgggaaag agttgtggtc gggttcggcc


 


451
agcatccgcg aaggcagcaa caacagcaac agcggcctgt tgggggcttt


 


501
ggtcggcgca gtggtcaatc agattgccaa cagcctgacc gaccgcggtt


 


551
atcaggtttc caaaaccgcc gcatacaacc tactgtcgcc ctattcccgc


 


601
aacggtatct tgaaaggtcc gagattcgtc gaagagcagc ccaaataa






This corresponds to the amino acid sequence <SEQ ID 870; ORF 235.ng>:










g235.pep




1
MKPLILGLAA VLALSACQVR KAPDLDYTSF KESKPASILV VPPLNESPDV


 


51
NGTWGMLAST AAPISEAGYY VFPAAVVEET FKENGLTNAA DIHAVRPEKL


 


101
HQIFGNDAVL YITVTEYGTS YQILDSVTTV SAKARLVDSR NGKELWSGSA


 


151
SIREGSNNSN SGLLGALVGA VVNQIANSLT DRGYQVSKTA AYNLLSPYSR


 


201
NGILKGPRFV EEQPK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 871>:










m235.seq




1
ATGAAACCTT TGATTTTAGG GCTTGCCGCC GTGTTGGCGC TGTCTGCCTG


 


51
CCAAGTTCAA AAAGCGCCCG ATTTCGACTA CACGTCATTC AAGGAAAGCA


 


101
AACCGGCTTC AATTTTGGTG GTTCCGCCGC TGAACGAATC GCCCGATGTC


 


151
AACGGAACAT GGGGTGTACT GGCTTCGACC GCCGCGCCGC TTTCCGAAGC


 


201
CGGCTATTAC GTCTTCCCCG CCGCAGTCGT GGAGGAAACC TTCAAACAAA


 


251
ACGGCTTGAC CAATGCCGCC GATATTCACG CCGTCCGGCC GGAAAAACTG


 


301
CATCAGATTT TCGGCAATGA TGCGGTTTTG TACATTACGG TTACCGAATA


 


351
CGGCACTTCA TATCAAATTT TAGACAGCGT GACGACCGTA TCCGCCAAAG


 


401
CACGGCTGGT CGATTCCCGC AACGGAAAAG AGTTGTGGTC GGGTTCGGCC


 


451
AGCATCCGCG AAGGCAGCAA CAACAGCAAC AGCGGCCTGT TGGGGGCTTT


 


501
GGTCAGCGCA GTGGTCAATC AGATTGCCAA CAGCCTGACC GACCGCGGTT


 


551
ATCAGGTTTC CAAAACCGCC GCATACAACC TGCTGTCGCC CTATTCTCAC


 


601
AACGGCATCT TGAAAGGTCC GAGATTCGTT GAAGAGCAGC CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 872; ORF 235>:










m235.pep




1
MKPLILGLAA VLALSACQVQ KAPDFDYTSF KESKPASILV VPPLNESPDV


 


51
NGTWGVLAST AAPLSEAGYY VFPAAVVEET FKQNGLTNAA DIHAVRPEKL


 


101
HQIFGNDAVL YITVTEYGTS YQILDSVTTV SAKARLVDSR NGKELWSGSA


 


151
SIREGSNNSN SGLLGALVSA VVNQIANSLT DRGYQVSKTA AYNLLSPYSH


 


201
NGILKGPRFV EEQPK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 235 shows 96.7% identity over a 215 aa overlap with a predicted ORF (ORF 235.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 873>:










a235.seq




1
ATGAAACCTT TGATTTTAGG GCTTGCCGCC GTGTTGGCGC TGTCTGCCTG


 


51
CCAAGTTCAA AAAGCGCCCG ATTTCGACTA CACGTCATTC AAGGAAAGCA


 


101
AACCGGCTTC AATTTTGGTG GTTCCGCCGC TGAACGAATC GCCCGATGTC


 


151
AACGGAACAT GGGGTGTACT GGCTTCGACC GCCGCGCCGC TTTCCGAAGC


 


201
CGGCTATTAC GTCTTCCCCG CCGCAGTCGT GGAGGAAACC TTCAAACAAA


 


251
ACGGCTTGAC CAATGCCGCC GATATTCACG CCGTCCGGCC GGAAAAACTG


 


301
CATCAGATTT TCGGCAATGA TGCGGTTTTG TACATTACGG TTACCGAATA


 


351
CGGCACTTCA TATCAAATTT TAGACAGCGT GACGACCGTA TCCGCCAAAG


 


401
CACGGCTGGT CGATTCCCGC AACGGAAAAG AGTTGTGGTC GGGTTCGGCC


 


451
AGCATCCGCG AAGGCAGCAA CAACAGCAAC AGCGGCCTGT TGGGGGCTTT


 


501
GGTCAGCGCA GTGGTCAATC AGATTGCCAA CAGCCTGACC GACCGCGGTT


 


551
ATCAGGTTTC TAAAACCGCC GCATACAACC TGCTGTCGCC CTATTCTCAC


 


601
AACGGCATCT TGAAAGGTCC GAGATTCGTC GAAGAGCAGC CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 874; ORF 235.a>:










a235.pep




1
MKPLILGLAA VLALSACQVQ KAPDFDYTSF KESKPASILV VPPLNESPDV


 


51
NGTWGVLAST AAPLSEAGYY VFPAAVVEET FKQNGLTNAA DIHAVRPEKL


 


101
HQIFGNDAVL YITVTEYGTS YQILDSVTTV SAKARLVDSR NGKELWSGSA


 


151
SIREGSNNSN SGLLGALVSA VVNQIANSLT DRGYQVSKTA AYNLLSPYSH


 


201
NGILKGPRFV EEQPK*






m235/a235 100.0% identity in 215 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 875>:










g236.seq




1
ATGGCGCGTT TCGCCTTCTC CGCCGACATT CTCCGCACAG CGTTTGCAGA


 


51
CGGTTTCATA ACCTGCAACC GCGCCCACAT CGCGGGTGTA ATGCCAGCAG


 


101
CGTTCGCATT TTTCGCCGTC GCTGGCTTTG GCGGCAACGG CAAGTTCATC


 


151
ACCGACTTTC ACTTCTGCTT TAGACACCAG CAGGGCAAAG CGCAATTCTT


 


201
CGCCCAAAGC ATTCAGATAG CCGGCCATTT CTTCCGGCGC GGTAATTTCG


 


251
GCTTCCGCCT GCAAggacga accgacagTT TTGTcggcGC GCAAAGGCTC


 


301
GAtagcggcg gTTACTGCTT CGCGCGCTTC GCGGATTGCC GTCCATTTTT


 


351
TCACCAGTTC GGCTTCGGCT TTTTCGTTGA TGGCCGGGAA CTCGTGCCAA


 


401
GTATGGAAGA GGACGCTGTC TTCTTCGCCG CCGCCGATGA TGTCCCACGC


 


451
TTCTTCGCCG GTGAAGCACA AAATCGGTGC AATCAAGAGA ACCAGGCTGC


 


501
GCGTGATGTG GTACAGGGCG GTTTGCGCGC TGCGGCGGGC GCGGCTGTCG


 


551
GCTTTGGTGG TGTAGAGGCG GTCTTTCAGG ATGTCGAGGT AGAACGCGCC


 


601
CAAGTCTTCC GAGCAGAAAG AAACAATGTC TTTCACGGCG AAGTGGAAGG


 


651
CATAGCGCGG ATAGTAACCG CCTGCCAAAC GCTCTTGCAG CCGCCGCGCC


 


701
AATACCAAGG CGTAGCGGTC GATTTCCACC ATATCCGCCT GTTGCACGGC


 


751
ATCTTCAATC GGATTAAAGT CGCTCAAATT GGCAAAcagG AAGCTCAAGG


 


801
TATTGCGGAT GCGGCGGTAG CTTTCGGTAA CGCGTTTGAG GATTTCTTTG


 


851
GAAatcgCCA ATtcgccgct gTAATCGGTG GATGCCGCCC ACAGGCGCAG


 


901
GATGTCCGCG CCGAATTCGT TATAGACTTC CTGCGGCGCG ACGACGTTGC


 


951
CGATGGATTT CGACATTTTG CGGCCGTTTT GGTCAACCAC GAAACCGTGG


 


1001
GTCAGCAGCT GTTTATACGG TGCGCGTCCC ATGGATGA






This corresponds to the amino acid sequence <SEQ ID 876; ORF 236.ng>:










g236.pep




1
MARFAFSADI LRTAFADGFI TCNRAHIAGV MPAAFAFFAV AGFGGNGKFI


 


51
TDFHFCFRHQ QGKAQFFAQS IQIAGHFFRR GNFGFRLQGR TDSFVGAQRL


 


101
DSGGYCFARF ADCRPFFHQF GFGFFVDGRE LVPSMEEDAV FFAAADDVPR


 


151
FFAGEAQNRC NQENQAARDV VQGGLRAAAG AAVGFGGVEA VFQDVEVERA


 


201
QVFRAERNNV FHGEVEGIAR IVTACQTLLQ PPRQYQGVAV DFHHIRLLHG


 


251
IFNRIKVAQI GKQEAQGIAD AAVAFGNAFE DFFGNRQFAA VIGGCRPQAQ


 


301
DVRAEFVIDF LRRDDVADGF RHFAAVLVNH ETVGQQLFIR CASHG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 877>:









m236.seq (partial)










1
..TTGCACGGAC GAACCGACGG TTTTGTCGGC GCGCAAAGGC TCGATGGCGG



 


51
  CGGTTACCGC TTCGCGGGCT TCGCGGATTG CCGTCCATTT TTTCACCAGT


 


101
  TCGGCTTCGG TTTTTTCGTT GATGGTCGGG AACTCGTGCC AAGTATGGAA


 


151
  GAGGACGCTG TCkTCTTCGC CGCCGCCGwT GAyGTCCCAC GCTTCTTCGC


 


201
  CGGTGAAGCA CAAAATCGGT GCAATCAAGA GAACCAAACT GCGTGTGATG


 


251
  TGATACAGGG CAGTTTGTGC GCTGCGGCGT GCATGGCTGT CTGCTTTGGT


 


301
  GGTGTAGAGG CGGTCTTTCA GGATGTCGAG GTAGAACGCA CCCAAGTCTT


 


351
  CCGAGCAGAA AGAAACArTG TCTTTTACGG CAAAGTGGaA kGCATAACGC


 


401
  GGATAGTAAT CGCCTGCCAG ACACTCTTGC AGCTGACGTG CCAATACCAC


 


451
  GGCGTAGCGG TCGATTTCCA CCATATCCGC CTGTTGCACG GCATCTTCAA


 


501
  TCGGATTAAA GTCGCTCAAG TTGGCAAACA AAAAGCTCAA GGTATTGCGG


 


551
  ATACGGCGGT AgCTTTCGGT TACGCGTTTG AGGATTTCTT TGGAAATCGC


 


601
  CAATTCGCCG CTGTAATCGG TAGATGCCGC CCACAGGCGC AGGATGTCTG


 


651
  CGCCGAATTC GTTATAAACC TCTTGCGGTG CAACGACGTT GCCGATGGAT


 


701
  TTCGACATTT TTTTGCCTTC GCCGTCGACA ACGAAACCAT GGGTCAGCAG


 


751
  CTGTTTATAC GGCGCGCGAC CCATTGA






This corresponds to the amino acid sequence <SEQ ID 878; ORF 236>:









m236.pep (partial)










1
..LHGRTDGFVG AQRLDGGGYR FAGFADCRPF FHQFGFGFFV DGRELVPSME



 


51
  EDAVXFAAAX DVPRFFAGEA QNRCNQENQT ACDVIQGSLC AAACMAVCFG


 


101
  GVEAVFQDVE VERTQVFRAE RNXVFYGKVE XITRIVIACQ TLLQLTCQYH


 


151
  GVAVDFHHIR LLHGIFNRIK VAQVGKQKAQ GIADTAVAFG YAFEDFFGNR


 


201
  QFAAVIGRCR PQAQDVCAEF VINLLRCNDV ADGFRHFFAF AVDNETMGQQ


 


251
  LFIRRATH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 236 shows 82.9% identity over a 258 aa overlap with a predicted ORF (ORF 236.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 879>:










a236.seq




1
ATGGCGCGTT TCGCCTTCTC CGCCGACATT CTCTGCACAG CGTTTGCAGA


 


51
CGGTTTCATG GCCTGCAACC GCGCCCACAT CGCGGGTGTA GTGCCAGCAG


 


101
CGTTCGCATT TTTCACCATC ACTGGCTTTA GCGGCAACGG CAAGTTCGCT


 


151
GCCTACTTTC ACTTCTGCTT TAGACACCAG CAAAGCAAAG CGCAATTCTT


 


201
CGCCCAAAGC ATTCAGATAG CCGGCCATTT CTTCCGGCGC GGTAATTTCG


 


251
GCTTCGGCTT GCAAGGACGA ACCGACGGTT TTGTCGGCGC GCAAAGGCTC


 


301
GATGGCGGCG GTTACCGCTT CGCGGGCTTC GCGGATTGCC GTCCATTTTT


 


351
TCACCAGTTC GGCTTCGGCT TTTTCGTTGA TGGTCGGGAA CTCGTGCCAA


 


401
GTATGGAAAA GCACGCTGTC TTCTGCGCCG CCGCCGATGA TGTCCCACGC


 


451
TTCTTCGCCG GTGAAGCACA AAATCGGTGC AATCAAGAGA ACCAGGCTGC


 


501
GCGTGATGTG GTACAGGGCG GTTTGCGCGC TGCGGCGGGC GCGGCTGTCG


 


551
GCTTTGGTGG TATAGAGGCG GTCTTTCAGG ATATCGAGGT AGAACGCGCC


 


601
CAAGTCTTCC GAGCAGAAAG AAACCATTTC TTTCACGGCA AAGTGGAAGG


 


651
CATAACGCGG ATAAAAATCA CCGGCAACGC GTTCTTGCAG CCGCCTTGCC


 


701
AACACCAAGG CATAGCGGTC GATTTCCACC ATATCCGCCT GTTGCACGGC


 


751
ATCTTCAATA GGATTGAAGT CGCTCAAGTT GGCAAACAAA AAGCTCAAGG


 


801
TATTGCGGAT ACGGCGGTAG CTTTCGGTTA CGCGCTTGAG GATTTCTTTG


 


851
GAAATCGCCA ATTCGCCGCT GTAATCGGTG GATGCCGCCC ACAGGCGCAG


 


901
GATGTCCGCG CCGAACTCGT TATACACTTC TTGCGGCGCG ACGACGTTGC


 


951
CGATGGATTT CGACATTTTG CGCCCGTTTT GATCCACCAC GAAACCATGG


 


1001
GTCAGCAGCT GTTTGTACGG CGCGCGACCC ATTGA






This corresponds to the amino acid sequence <SEQ ID 880; ORF 236.a>:










a236.pep




1
MARFAFSADI LCTAFADGFM ACNRAHIAGV VPAAFAFFTI TGFSGNGKFA


 


51
AYFHFCFRHQ QSKAQFFAQS IQIAGHFFRR GNFGFGLQGR TDGFVGAQRL


 


101
DGGGYRFAGF ADCRPFFHQF GFGFFVDGRE LVPSMEKHAV FCAAADDVPR


 


151
FFAGEAQNRC NQENQAARDV VQGGLRAAAG AAVGFGGIEA VFQDIEVERA


 


201
QVFRAERNHF FHGKVEGITR IKITGNAFLQ PPCQHQGIAV DFHHIRLLHG


 


251
IFNRIEVAQV GKQKAQGIAD TAVAFGYALE DFFGNRQFAA VIGGCRPQAQ


 


301
DVRAELVIHF LRRDDVADGF RHFAPVLIHH ETMGQQLFVR RATH*






m236/a236 81.0% identity in 258 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 881>:










g237.seq




1
atgcgggaca aggttggcgg taatatcgca ctccccgccc cacgaatatt


 


51
cgattctaac atcggcaagc tgcggaaaaa ctttaagcat atcttggcgg


 


101
acaagctcgg tcatacgcgc aggattgtcg ataaattcgt tatccttacc


 


151
gccgaaaagc agcctgccgt ccgcgctgag gcggtaataa tccaaaatat


 


201
ggcggttgtc gcatactgcc atattgttgc ggataagccc ttttgtgcgc


 


251
gcgcccaagg gttcggtggc aataataaag gtgctgacgg caatcgcctt


 


301
gcgttccaaa ggccggaata tcgggttcaa accgacataa gtattgacgg


 


351
catagaccac atttttacac tcgacgctgc cttcgggcgt gtaaaccagc


 


401
caaccgtttt gatacggttc gatgcgcgtc atcggggatt gctcgaaaat


 


451
ctgcgcgccg gcttcggcag cggcgctggc aacacccaac gtgtaattga


 


501
gcggatgaag atgcccggac aagggatcga actgtgcgcc ttggtacata


 


551
tcgctgtcaa gctgctgttt caactcggct ttatcccaaa gttgataatg


 


601
actcgcaccg taatgccgtt gggcgtgttc atgccactgc tgcaactctt


 


651
cccaatgctg cggacggacg gcaaccgtgg cataaccgcg ctgccaatcg


 


701
caatcgatgg catgtttgcg gacgcgttcg tccaccagtt cgaccgcctg


 


751
caaagactgt tgccaaaacc attgcgcctg ctccaagccg acctgttttt


 


801
caatttcccc cataccgcag gcgtagtcgc tgataacctg cccgccactc


 


851
ctgccggacg cgccgaagcc gatacgtgcg gcttccaaaa cgacggcttc


 


901
atgtccgtgt tccgccagcg gcaatgcggt acacaaaccg ctcaaaccgc


 


951
cgccgataat gcaggtttcg gctttcagac ggcattggag tttcggataa


 


1001
acagtatgcg gattaaccga actaaaataa taagaaggca gatattcttg


 


1051
aaaatcaggg cgaatcattg tgtttgcttt atcgggtata ttttcggacg


 


1101
gaatgataca gactgtcggg ccatatcgtc caaacagaaa atcggttga






This corresponds to the amino acid sequence <SEQ ID 882; ORF 237.ng>:










g237.pep




1
MRDKVGGNIA LPAPRIFDSN IGKLRKNFKH ILADKLGHTR RIVDKFVILT


 


51
AEKQPAVRAE AVIIQNMAVV AYCHIVADKP FCARAQGFGG NNKGADGNRL


 


101
AFQRPEYRVQ TDISIDGIDH IFTLDAAFGR VNQPTVLIRF DARHRGLLEN


 


151
LRAGFGSGAG NTQRVIERMK MPGQGIELCA LVHIAVKLLF QLGFIPKLIM


 


201
TRTVMPLGVF MPLLQLFPML RTDGNRGITA LPIAIDGMFA DAFVHQFDRL


 


251
QRLLPKPLRL LQADLFFNFP HTAGVVADNL PATPAGRAEA DTCGFQNDGF


 


301
MSVFRQRQCG TQTAQTAADN AGFGFQTALE FRINSMRINR TKIIRRQIFL


 


351
KIRANHCVCF IGYIFGRNDT DCRAISSKQK IG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 883>:










m237.seq




1
ATGCGGGACA AGGTTGGCGG TAATGTCGCA CTCCCCGCCC CACGAATATT


 


51
CGATTTTGAC ATCGGCAAGC TGCGGAAAAA CTTTAAGCAT ATCTTGGCGG


 


101
ACAAGCTCGG TCATaCGCTC AGGATTGTCG ATAAACTCGT TATCCTTACC


 


151
GCCGAAAAGC AGTCTGCCGT CCGCGCTGAG GCGGTAATAA TCCAAAATAT


 


201
GGCGGTTGTC GCATACTGCC ATATTGTTAC GGATAAGCCC TTTTGCGCGC


 


251
GCCCCCAAGG GTTCGGTCGC AATAATAAAG GTGCTGACAG CAATCGCCTT


 


301
GCGTTCCAAA GGCCGGAATA TCGGGTTCAA ACCTGCATAA GTATTGACAG


 


351
CATAGACCAC ATTTTTGCAC TCGACGCTGC CTTCGGGCGT GTAAACCAGC


 


401
CAACCGTTTT GATGCGGTTC GATGCACGTC ATCGGGGATT GCTCGAAAAT


 


451
CTGCGCACCG GCTTCGGCAG CGGCACGAGC GATGCCCAAA GTGTAAGTGA


 


501
GCGGATGCAG GTGTCCGGAT AAGGGGTCGA ATTGTGCCCC TTGGTACATA


 


551
TCGCTGTCAA GCTGCTGTTT CAACTCGGCT TTATCCCAAA GTTGATAATG


 


601
ACTCGCACCG TAATGCCGTT GGGCGTGTTC ATGCCACTGC TGCAACTCTT


 


651
CCCAATGCTG CGGACGGACG GCAACCGTGG CATAACCGCG CTGCCAATCA


 


701
CAATCGACGG CATGTTTGCG GACGCGTTCG TCCACCAGTT CGACCGCCTG


 


751
CAAAGACTGT TGCCAAAACC ATTGCGCCTG CTCCAAGCCG ACCTGTTTTT


 


801
CAATTTCCCC CATACCGCAG nCGTAATCGC TGATAACCTG CCCGCCACTC


 


851
CGTCCCGACG CGCCGAAACC GATACGCGCG GCTTCCAACA CAACCGTTTC


 


901
ATGTCCCTGC TCCGCCAAGG GCAATGCAGT GCACAAACCA CCCAATCCGC


 


951
CGCCGATGAT ACAGGTATCG GTTTTCAGAC GGCATTGAAG TTtCGGATAA


 


1001
ACAGTATGAG GATTAACCGA ACTGAAATAA TAAGAAGGCA GATATTCTTG


 


1051
AAAATCAGGG CGAATCATTG TGTTTGCTTT ATCAGGTGTA TTTTCGGACG


 


1101
GAATGATACA GGCTGTCGGG CCATATCGTC CAwACAGAAA ATCGGTTGA






This corresponds to the amino acid sequence <SEQ ID 884; ORF 237>:










m237.pep




1
MRDKVGGNVA LPAPRIFDFD IGKLRKNFKH ILADKLGHTL RIVDKLVILT


 


51
AEKQSAVRAE AVIIQNMAVV AYCHIVTDKP FCARPQGFGR NNKGADSNRL


 


101
AFQRPEYRVQ TCISIDSIDH IFALDAAFGR VNQPTVLMRF DARHRGLLEN


 


151
LRTGFGSGTS DAQSVSERMQ VSGXGVELCP LVHIAVKLLF QLGFIPKLIM


 


201
TRTVMPLGVF MPLLQLFPML RTDGNRGITA LPITIDGMFA DAFVHQFDRL


 


251
QRLLPKPLRL LQADLFFNFP HTAXVIADNL PATPSRRAET DTRGFQHNRF


 


301
MSLLRQGQCS AQTTQSAADD TGIGFQTALK FRINSMRINR TEIIRRQIFL


 


351
KIRANHCVCF IRCIFGRNDT GCRAISSXQK IG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 237 shows 86.1% identity over a 382 aa overlap with a predicted ORF (ORF 237.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 885>:










a237.seq




1
ATGCGGGACA AGGTTGGCGG TAATGTCGCA CTCCCCGCCC CACGAATATT


 


51
CGATTTTGAC ATCGGCAAGC TGCGGAAAAA CTTTAAGCAT ATCTTGGCGG


 


101
ACAAGCTCGG TCATACGCGC GGGATTGTCG ATAAACTCGT TATCCTTACC


 


151
GCCGAAAAGC AGTCTGCCGT CCGCGCTGAG GCGGTAATAA TCCAAAATAT


 


201
GACGGTTGTC GCATACTGCC ATATTGTTGC GGATAAGCCC TTTTGCACGC


 


251
GCGCCCAAGG GTTCTGTGGC AATAATAAAG GTGCTGACAG CAATCGCCTT


 


301
GCGCTCCAAA GGCTTGAATA TCGGATTCAA ACCGGCATAA GTATTGACGG


 


351
CGTACACCAG ATTTTTGCAT TCGACGCTGC CTTCGGGGGT GTAAACCAGC


 


401
CAACCGTTTT GATAAGGTTC AATGCGTATC ATGGGAGAAT GCTCAAAAAT


 


451
CTTCGTACCA GCTTCGGCAG CGGCGCGGGC GATGCCCAAC GTGTAATTGA


 


501
GCGGATGGAG ATGCCCGGAC AAGGGATCGA ACTGTGCGCC TTGGTACATA


 


551
TCGCTGTCAA GCTGCTGCTT CAGTTCAGTG TTATCCCAGA GTTGATAATG


 


601
AGTTGCACCG TAATATTTTT GGGCGTGCTC ATGCCATTGT TGCAATTCTT


 


651
CCCAATGCTG CGAACGGATG GCAACCGTGG CATAACCGCG CTGCCAATCG


 


701
CAATCAATGG CATGTTTGCG GACGCGTTCG TCCACCAGTT CGACCGCCTG


 


751
CAAAGACTGT TGCCAAAACC ATTGCGCTTG CTCCAAACCG ACCTGTTTTT


 


801
CAATTTCCTC CATACCGCAG GCGTAATCGC TGATAACCTG CCCGCCACTC


 


851
CGTCCCGACG CGCCGAAACC GATACGCGCG GCTTCCAACA CAACCGTTTC


 


901
ATGTCCCTGC TCCGCCAAGG GCAATGCAGT GCACAAACCA CTCAATCCGC


 


951
CGCCGATGAT ACAGGTATCG GTTTTCAGAC GGCATTGAAG TTTCGGATAA


 


1001
ACAGTATGAG GATTAACCGA ACTGAAATAA TAAGAAGGCA GATATTCTTG


 


1051
AAAATCAGGG CGAATCATTG TGTTTGCTTT ATCGGGTATA TTTTCGGACG


 


1101
GAATGATACA GGCTGTCGAG CCATATCGTC CAAACAGAAA ATCGGTTGA






This corresponds to the amino acid sequence <SEQ ID 886; ORF 237.a>:










a237.pep




1
MRDKVGGNVA LPAPRIFDFD IGKLRKNFKH ILADKLGHTR GIVDKLVILT


 


51
AEKQSAVRAE AVIIQNMTVV AYCHIVADKP FCTRAQGFCG NNKGADSNRL


 


101
ALQRLEYRIQ TGISIDGVHQ IFAFDAAFGG VNQPTVLIRF NAYHGRMLKN


 


151
LRTSFGSGAG DAQRVIERME MPGQGIELCA LVHIAVKLLL QFSVIPELIM


 


201
SCTVIFLGVL MPLLQFFPML RTDGNRGITA LPIAINGMFA DAFVHQFDRL


 


251
QRLLPKPLRL LQTDLFFNFL HTAGVIADNL PATPSRRAET DTRGFQHNRF


 


301
MSLLRQGQCS AQTTQSAADD TGIGFQTALK FRINSMRINR TEIIRRQIFL


 


351
KIRANHCVCF IGYIFGRNDT GCRAISSKQK IG*






m237/a237 85.6% identity in 382 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 887>:










g238.seq




1
atgaatttgc ctattcaaaa attcatgatg ctgttggcag cggcaatatc


 


51
gatgctgcat atccccatta gtcatgcgaa cggtttggat gcccgtttgc


 


101
gcgatgatat gcaggcaaaa cactacgaac cgggtggcaa ataccatctg


 


151
tttggtaatg ctcgcggcag tgttaaaaat cgggtttgcg ccgtccaaac


 


201
atttgatgca actgcggtcg gccccatact gcctattaca cacgaacgga


 


251
caggatttga aggtgttatc ggctatgaaa cccatttttc aggacacgga


 


301
cacgaagtac acagtccgtt cgataatcat gattcaaaaa gcacttctga


 


351
tttcagcggc ggcgtagacg gcggttttac cgtttaccaa cttcatcgga


 


401
cagggtcgga aatacatccc gcagacggat atgacgggcc tcaaggcggc


 


451
ggttatccgg aaccacaagg ggcaagggat atatacagct accatatcaa


 


501
aggaacttca accaaaacaa agataaacac tgttccgcaa gccccttttt


 


551
cagaccgctg gctaaaagaa aatgccggtg ccgcttccgg ttttctcagc


 


601
cgtgcggatg aagcaggaaa actgatatgg gaaaacgacc ccgataaaaa


 


651
ttggcgggct aaccgtatgg atgatattcg cggcatcgtc caaggtgcgg


 


701
ttaatccttt tttaacgggt tttcaagggg tagggattgg ggcaattaca


 


751
gacagtgcgg taagcccggt cacagataca gccgctcagc agactctaca


 


801
aggtattaat gatttaggaa atttaagtcc ggaagcacaa cttgccgccg


 


851
cgagcctatt acaggacagt gcctttgcgg taaaagacgg catcaattcc


 


901
gccagacaat gggctgatgc ccatccgaat ataacagcaa cagcccaaac


 


951
tgcccttgcc gtagcagagg ccgcaggtac ggtttggcgc ggtaaaaaag


 


1001
tagaacttaa cccgaccaaa tgggattggg ttaaaaatac cggctataaa


 


1051
aaacctgctg cccgccatat gcagactgta gatggggaga tggcaggggg


 


1101
gaatagaccg cctaaatcta taacgtcgga aggaaaagct aatgctgcaa


 


1151
cctatcctaa gttggttaat cagctaaatg agcaaaactt aaataacatt


 


1201
gcggctcaag atccaagatt gagtctagct attcatgagg gtaaaaaaaa


 


1251
ttttccaata ggaactgcaa cttatgaaga ggcagataga ctaggtaaaa


 


1301
tttgggttgg tgagggtgca agacaaacta gtggaggcgg atggttaagt


 


1351
agagatggca ctcgacaata tcggccacca acagaaaaaa aatcacaatt


 


1401
tgcaactaca ggtattcaag caaattttga aacttatact attgattcaa


 


1451
atgaaaaaag aaataaaatt aaaaatggac atttaaatat taggtaa






This corresponds to the amino acid sequence <SEQ ID 888; ORF 238.ng>:










g238.pep




1
MNLPIQKFMM LLAAAISMLH IPISHANGLD ARLRDDMQAK HYEPGGKYHL


 


51
FGNARGSVKN RVCAVQTFDA TAVGPILPIT HERTGFEGVI GYETHFSGHG


 


101
HEVHSPFDNH DSKSTSDFSG GVDGGFTVYQ LHRTGSEIHP ADGYDGPQGG


 


151
GYPEPQGARD IYSYHIKGTS TKTKINTVPQ APFSDRWLKE NAGAASGFLS


 


201
RADEAGKLIW ENDPDKNWRA NRMDDIRGIV QGAVNPFLTG FQGVGIGAIT


 


251
DSAVSPVTDT AAQQTLQGIN DLGNLSPEAQ LAAASLLQDS AFAVKDGINS


 


301
ARQWADAHPN ITATAQTALA VAEAAGTVWR GKKVELNPTK WDWVKNTGYK


 


351
KPAARHMQTV DGEMAGGNRP PKSITSEGKA NAATYPKLVN QLNEQNLNNI


 


401
AAQDPRLSLA IHEGKKNFPI GTATYEEADR LGKIWVGEGA RQTSGGGWLS


 


451
RDGTRQYRPP TEKKSQFATT GIQANFETYT IDSNEKRNKI KNGHLNIR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 889>:










m238.seq




1
ATGAATTTGC CTATTCAAAA ATTCATGATG CTGTTTGCAG CAGCAATATC


 


51
GTTGCTGCAA ATCCCCATTA GTCATGCGAA CGGTTTGGAT GCCCGTTTGC


 


101
GCGATGATAT GCAGGCAAAA CAcTACGAAC CGGGTGGTAA ATACCATCTG


 


151
TTTGGTAATG CTCGCGGCAG TGTTAAAAAG CGGGTTTACG CCGTCCAGAC


 


201
ATTTGATGCA ACTGCGGTCA GTCCTGTACT GCCTATTACA CACGAACGGA


 


251
CAGGGTTTGA AGGTGTTATC GGTTATGAAA CCCATTTTTC AGGGCACGGA


 


301
CATGAAGTAC ACAGTCCGTT CGATCATCAT GATTCAAAAA GCACTTCTGA


 


351
TTTCAGCGGC GGTGTAGACG GCGGTTTTAC TGTTTACCAA CTTCATCGAA


 


401
CAGGGTCGGA AATCCATCCG GAGGATGGAT ATGACGGGCC GCAAGGCAGC


 


451
GATTATCCGC CCCCCGGAGG AGCAAGGGAT ATATACAGCT ATTATGTCAA


 


501
AGGAACTTCA ACAAAAACAA AGACTAATAT TGTCCCTCAA GCCCCATTTT


 


551
CAGACCGTTG GCTAAAAGAA AATGCCGGTG CCGCCTCTGG TTTTTTCAGC


 


601
CGTGCGGATG AAGCAGGAAA ACTGATATGG GAAAGCGACC CCAATAAAAA


 


651
TTGGTGGGCT AACCGTATGG ATGATGTTCG CGGCATCGTC CAAGGTGCGG


 


701
TTAATCCTTT TTTAATGGGT TTTCAAGGAG TAGGGATTGG GGCAATTACA


 


751
GACAGTGCAG TAAGCCCGGT CACAGATACA GCCGCGCAGC AGACTCTACA


 


801
AGGTATTAAT GATTTAGGAA AATTAAGTCC GGAAGCACAA CTTGCTGCCG


 


851
CGAGCCTATT ACAGGACAGT GCTTTTGCGG TAAAAGACGG TATCAACTCT


 


901
GCCAAACAAT GGGCTGATGC CCATCCAAAT ATAACAGCTA CTGCCCAAAC


 


951
TGCCCTTTCC GCAGCAGAGG CCGCAGGTAC GGTTTGGAGA GGTAAAAAAG


 


1001
TAGAACTTAA CCCGACTAAA TGGGATTGGG TTAAAAATAC CGGTTATAAA


 


1051
AAACCTGCTG CCCGCCATAT GCAGACTTTA GATGGGGAGA TGGCAGGTGG


 


1101
GAATAAACCT ATTAAATCTT TACCAAACAG TGCCGCTGAA AAAAGAAAAC


 


1151
AAAATTTTGA GAAGTTTAAT AGTAACTGGA GTTCAGCAAG TTTTGATTCA


 


1201
GTGCACAAAA CACTAACTCC CAATGCACCT GGTATTTTAA GTCCTGATAA


 


1251
AGTTAAAACT CGATACACTA GTTTAGATGG AAAAATTACA ATTATAAAAG


 


1301
ATAACGAAAA CAACTATTTT AGAATCCATG ATAATTCACG AAAACAGTAT


 


1351
CTTGATTCAA ATGGTAATGC TGTGAAAACC GGTAATTTAC AAGGTAAGCA


 


1401
AGCAAAAGAT TATTTACAAC AACAAACTCA TATCAGGAAC TTAGACAAAT


 


1451
GA






This corresponds to the amino acid sequence <SEQ ID 890; ORF 238>:










m238.pep




1
MNLPIQKFMM LFAAAISLLQ IPISHANGLD ARLRDDMQAK HYEPGGKYHL


 


51
FGNARGSVKK RVYAVQTFDA TAVSPVLPIT HERTGFEGVI GYETHFSGHG


 


101
HEVHSPFDHH DSKSTSDFSG GVDGGFTVYQ LHRTGSEIHP EDGYDGPQGS


 


151
DYPPPGGARD IYSYYVKGTS TKTKTNIVPQ APFSDRWLKE NAGAASGFFS


 


201
RADEAGKLIW ESDPNKNWWA NRMDDVRGIV QGAVNPFLMG FQGVGIGAIT


 


251
DSAVSPVTDT AAQQTLQGIN DLGKLSPEAQ LAAASLLQDS AFAVKDGINS


 


301
AKQWADAHPN ITATAQTALS AAEAAGTVWR GKKVELNPTK WDWVKNTGYK


 


351
KPAARHMQTL DGEMAGGNKP IKSLPNSAAE KRKQNFEKFN SNWSSASFDS


 


401
VHKTLTPNAP GILSPDKVKT RYTSLDGKIT IIKDNENNYF RIHDNSRKQY


 


451
LDSNGNAVKT GNLQGKQAKD YLQQQTHIRN LDK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 238 shows 86.0% identity over a 401 aa overlap with a predicted ORF (ORF 238.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 891>:









a238.seq (partial)










1
ATGAATTTGC CTATTCAAAA ATTCATGATG CTGTTTGCAG CAGCAATATC



 


51
GTTGCTGCAA ATCCCCATTA GTCATGCGAA CGGTTTGGAT GCCCGTTTGC


 


101
GCGATGATAT GCAGGCAAAA CACTACGAAC CGGGTGGTAA ATACCATCTG


 


151
TTTGGTAATG CTCGCGGCAG TGTTAAAAAT CGGGTTTACG CCGTCCAAAC


 


201
ATTTGATGCA ACTGCGGTCG GCCCCATACT GCCTATTACA CACGAACGGA


 


251
CAGGATTTGA AGGCATTATC GGTTATGAAA CCCATTTTTC AGGACATGGA


 


301
CATGAAGTAC ACAGTCCGTT CGATAATCAT GATTCAAAAA GCACTTCTGA


 


351
TTTCAGCGGC GGCGTAGACG GTGGTTTTAC CGTTTACCAA CTTCATCGGA


 


401
CAGGGTCGGA AATCCATCCG GAGGATGGAT ATGACGGGCC GCAAGGCAGC


 


451
GATTATCCGC CCCCCGGAGG AGCAAGGGAT ATATACAGCT ACTATGTCAA


 


501
AGGAACTTCA ACAAAAACAA AGAGTAATAT TGTTCCCCGA GCCCCATTTT


 


551
CAGACCGCTG GCTAAAAGAA AATGCCGGTG CCGCCTCTGG TTTTTTCAGC


 


601
CGTGCTGATG AAGCAGGAAA ACTGATATGG GAAAGCGACC CCAATAAAAA


 


651
TTGGTGGGCT AACCGTATGG ATGATATTCG CGGCATCGTC CAAGGTGCGG


 


701
TTAATCCTTT TTTAATGGGT TTTCAAGGAG TAGGGATTGG GGCAATTACA


 


751
GACAGTGCAG TAAGCCCGGT CACAGATACA GCCGCGCAGC AGACTCTACA


 


801
AGGTATTAAT CATTTAGGAA ATTTAAGTCC CGAAGCACAA CTTGCGGCTG


 


851
CAACCGCATT ACAAGACAGT GCTTTTGCGG TAAAAGACGG TATCAATTCC


 


901
GCCAGACAAT GGGCTGATGC CCATCCGAAT ATAACTGCAA CAGCCCAAAC


 


951
TGCCCTTGCC GTAGCAGAGG CCGCAACTAC GGTTTGGGGC GGTAAAAAAG


 


1001
TAGAACTTAA CCCGACCAAA TGGGATTGGG TTAAAAATAC CGGCTATAAA


 


1051
ACACCTGCTG TTCGCACCAT GCATACTTTG GATGGGGAAA TGGCCGGTGG


 


1101
GAATAGACCG CCTAAATCTA TAACGTCCAA CAGCAAAGCA GATGCTTCCA


 


1151
CACAA






This corresponds to the amino acid sequence <SEQ ID 892; ORF 238.a>:









a238.pep (partial)










1
MNLPIQKFMM LFAAAISLLQ IPISHANGLD ARLRDDMQAK HYEPGGKYHL



 


51
FGNARGSVKN RVYAVQTFDA TAVGPILPIT HERTGFEGII GYETHFSGHG


 


101
HEVHSPFDNH DSKSTSDFSG GVDGGFTVYQ LHRTGSEIHP EDGYDGPQGS


 


151
DYPPPGGARD IYSYYVKGTS TKTKSNIVPR APFSDRWLKE NAGAASGFFS


 


201
RADEAGKLIW ESDPNKNWWA NRMDDIRGIV QGAVNPFLMG FQGVGIGAIT


 


251
DSAVSPVTDT AAQQTLQGIN HLGNLSPEAQ LAAATALQDS AFAVKDGINS


 


301
ARQWADAHPN ITATAQTALA VAEAATTVWG GKKVELNPTK WDWVKNTGYK


 


351
TPAVRTMHTL DGEMAGGNRP PKSITSNSKA DASTQ






m238/a238 91.9% identity in 385 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 893>:










g239.seq




1
atgttccacc ataaaggtat tgcccgaaac cggcggatgg aggttttgtt


 


51
tttctgccgc cgccctgatc gcttcgtgat tcgccaaacg cgcctgttgc


 


101
agcctcattt gcgcataatc ctgctccaag gcgatttcct gttttttcgc


 


151
cttgtccaaa gctgtgaagt tgagcctgta ctggttttgc tgcatcacaa


 


201
cggaaaaagc ggaaacgcac accgcaagca gcagaaagaa attcgatttg


 


251
ttcattgccg ttcagacgtt tttctctgtt attattccgg tatcggaccg


 


301
gcagtccgct ccgccacacg caaaactgcg ctcctcgccc tcgggttggc


 


351
ggcaatttcc gcttcacccg gctttaatgc cctgcccacg attttcaggg


 


401
gcggatcggg caaatccgct tctctgaccg ccgcccagct cggcaggggc


 


451
tcgtgttgcg aatatttttt gacaaactgc ttcacaatgc ggtcttccaa


 


501
cgaatggaaa gcaatgaccg ccaaacgccc gccctctttc agacggcaca


 


551
tgacctgcgg caataccgcc cctacttctt caagctcgcg gttaataaag


 


601
atgcggattg cctggaaggt gcgcgtcgca ggatcctgcc cccgctcgcg


 


651
agtacggacg ttttgtgcca cgatctgcgc cagcttgcgg gttgtatcga


 


701
ttggactttc cgcccgttgc gcgacaatgg cgcgcacaat ctggcggcta


 


751
aaccgctctt caccataa






This corresponds to the amino acid sequence <SEQ ID 894; ORF 239.ng>:










g239.pep




1
MFHHKGIARN RRMEVLFFCR RPDRFVIRQT RLLQPHLRII LLQGDFLFFR


 


51
LVQSCEVEPV LVLLHHNGKS GNAHRKQQKE IRFVHCRSDV FLCYYSGIGP


 


101
AVRSATRKTA LLALGLAAIS ASPGFNALPT IFRGGSGKSA SLTAAQLGRG


 


151
SCCEYFLTNC FTMRSSNEWK AMTAKRPPSF RRHMTCGNTA PTSSSSRLIK


 


201
MRIAWKVRVA GSCPRSRVRT FCATICASLR VVSIGLSARC ATMARTIWRL


 


251
NRSSP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 895>:










m239.seq




1
ATGCTCCACC ATAAAGGTmy kGCCCGAAAC CGGCkGATGG AGGTTTTGTT


 


51
TTTCTGCCGC CGCCCTGATC GCTTCGTGGT TCGCCAAACG CGCCTGTTGC


 


101
AGCCTCATTT GCGCATAATC CTGCTCCAAG GCGATTTCCT GTTTTTTCGC


 


151
CTTATCCAAA GCTGTGAAAT TGAGCCTGTA CTGGTTTTGC TGCATCACAA


 


201
CGGAAAAAGC GGAAACGCAC ACCGCAAGCA GCAGAAGGAA ATTCAATTTG


 


251
TTCATTGCCA TTCAGACGTT TTTCTCTGTG ATTGTTCCGG TATCGGACCG


 


301
GCAGTCCGCT CCGCCACACG CAAAACCGCA CTTCTCGCCC TCGGATTGGC


 


351
GGCAATTTCC GCCTCACCCG GCTTTAATGC CCTGCCCACG ATTTTCAGGG


 


401
GCAGCTCGGG CAAATCCGCT TCCCTGaCCG CCGCCCAGCG CGGCAGGGGC


 


451
GCGTGTTGCG AATATTTTTT GACAAACTGC TTCACAATGC GATCTTCCAA


 


501
CGAATGGAAA GCAATGACCG CCAAACGTCC GCCCTCTTTC AGACGACACA


 


551
TGACCTGCGG CAATACTGCC CCTACTTCTT CAAGCTCGCG GTTAATAAAG


 


601
ATGCGGACCG CCTGGAAGGT GCGCGTCGCA GGATCCTGCC CCCGCTCGCG


 


651
AGTACGGACG TTTTGTGCCA CGATCTGCGC CAGCTTGCGG GTTGTATCGA


 


701
TTGGACTTTC CGCCCGTTGC GCAACAATGG CGCGCGCAAT cCGGCGGCTa


 


751
AACCGCTCTT cACCATAA






This corresponds to the amino acid sequence <SEQ ID 896; ORF 239>:










m239.pep




1
MLHHKGXARN RXMEVLFFCR RPDRFVVRQT RLLQPHLRII LLQGDFLFFR


 


51
LIQSCEIEPV LVLLHHNGKS GNAHRKQQKE IQFVHCHSDV FLCDCSGIGP


 


101
AVRSATRKTA LLALGLAAIS ASPGFNALPT IFRGSSGKSA SLTAAQRGRG


 


151
ACCEYFLTNC FTMRSSNEWK AMTAKRPPSF RRHMTCGNTA PTSSSSRLIK


 


201
MRTAWKVRVA GSCPRSRVRT FCATICASLR VVSIGLSARC ATMARAIRRL


 


251
NRSSP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 239 shows 93.7% identity over a 255 aa overlap with a predicted ORF (ORF 239.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 897>:










a239.seq




1
ATGCTCCACC ATAAAGGTAT TGCCCGAAAC CGGCGGATGG AGGTTTTGTT


 


51
TTTCTGCCGC CGCCCTGATC GCTTCGTGGT TCGCCAAACG CGCCTGTTGC


 


101
AGCCTCATTT GCGCATAATC CTGCTCCAAG GCGATTTCCT GTTTTTTCGC


 


151
CTTATCCAAA GCTGTGAAGT TGAGCCTGTA CTGGTTTTGC TGCATCACAA


 


201
CGGAAAAAGC GGAAACGCAC ACCGCAAGCA GCAGAAGGAA ATTCAATTTG


 


251
TTCATTGCCA TTCAGACGTT TTTCTCTGTG ATTGTTCCGG TATCGGACCG


 


301
GCAGTCCGCT CCGCCACACG CAAAACCGCA CTTCTCGCCC TCGGATTGGC


 


351
GGCAATTTCC GCCTCACCCG GCTTTAATGC CCTGCCCGCG ATTTTCAGGG


 


401
GCGGCTCGGG CAAATCCGCT TCCCTGACCG CCGCCCAGCG CGGCAGGGGC


 


451
GCGTGTTGCG AATATTTTTT GACAAACTGC TTCACAATGC GGTCTTCCAA


 


501
CGAATGGAAA GCAATGACCG CCAAACGTCC GCCCTCTTTC AGACGACACA


 


551
TGACCTGCGG CAATACTGCC CCTACTTCTT CAAGCTCGCG GTTAATAAAG


 


601
ATGCGGATTG CCTGGAAGGT GCGCGTCGCA GGATCCTGCC CCCGCTCGCG


 


651
AGTACGGACG TTTTGTGCCA CGATCTGCGC CAGCTTGCGG GTTGTATCGA


 


701
TTGGACTTTC CGCCCGTTGC GCAACAATGG CGCGCGCAAT CTGGCGGCTA


 


751
AACCGCTCTT CACCATAA






This corresponds to the amino acid sequence <SEQ ID 898; ORF 239.a>:










a239.pep




1
MLHHKGIARN RRMEVLFFCR RPDRFVVRQT RLLQPHLRII LLQGDFLFFR


 


51
LIQSCEVEPV LVLLHHNGKS GNAHRKQQKE IQFVHCHSDV FLCDCSGIGP


 


101
AVRSATRKTA LLALGLAAIS ASPGFNALPA IFRGGSGKSA SLTAAQRGRG


 


151
ACCEYFLTNC FTMRSSNEWK AMTAKRPPSF RRHMTCGNTA PTSSSSRLIK


 


201
MRIAWKVRVA GSCPRSRVRT FCATICASLR VVSIGLSARC ATMARAIWRL


 


251
NRSSP*






m239/a239 97.3% identity in 255 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 899>:










g240.seq




1
atgatagaag tcatacattt cttcggcgcc gaaacgcgca gacagtttgc


 


51
ttgtgccgac gttggacgat ttctgcataa tgccgcgcac atccaaagag


 


101
gggtaaacat gggtatcatc gcgcacggga gacggtccga ttttataagg


 


151
ctgcgtattc agccgttcgt tcaaatcggt tttgcccgca tccaatgcct


 


201
tcgcaatcac gaacggtttg attgccgaac caggttcgat catatcggtt


 


251
acggcacggt tgcgccgctg ttcgctgtct gcccggccgg gtctgttggg


 


301
atcgtaggcg ggcgtattgg ccaaggcgag gatttccccc gtgcgggcat


 


351
ccaaaaccac caccgttccg gcttttgcct gatggtattc gaccgccttg


 


401
ttcaactctt cataggccaa ggtctgaatc ctctgatcga gggaaaggat


 


451
gatgtctttg ccgttttgcg gtgctttatt gcgcggggag tccaagctgt


 


501
ccacaatatt gccctgccgg tcccgcaaaa caacttccgc gccgtcttcg


 


551
ccatacaggc tgtcttcaag cgaaagttcc aaaccttcct gacctttgcc


 


601
gtcaatatcg gtaaatccga tgacgtgtgc aaacaggttg cccatcgggt


 


651
aatggcgttt taa






This corresponds to the amino acid sequence <SEQ ID 900; ORF 240.ng>:










g240.pep




1
MIEVIHFFGA ETRRQFACAD VGRFLHNAAH IQRGVNMGII AHGRRSDFIR


 


51
LRIQPFVQIG FARIQCLRNH ERFDCRTRFD HIGYGTVAPL FAVCPAGSVG


 


101
IVGGRIGQGE DFPRAGIQNH HRSGFCLMVF DRLVQLFIGQ GLNPLIEGKD


 


151
DVFAVLRCFI ARGVQAVHNI ALPVPQNNFR AVFAIQAVFK RKFQTFLTFA


 


201
VNIGKSDDVC KQVAHRVMAF *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 901>:










m240.seq




1
ATGATAGAAG TCATACATTT CTTCGGCACC GAAACGCGCA GACAGTTTGC


 


51
TTGTGCCGAC GTTGGACGAT TTCTGCATGA TGCCGCGCAC ATCCAAAGAG


 


101
GGGTAAACAT GGGTATCGCG CACGGGAGAC GGTCCGATTT TATAAGGCTG


 


151
CGTATTCAGC CGTTCGTTCA AATCGGTTTT GCCCGCATCC AATGCCTTCG


 


201
CAATCACAAA CGGTTTGATT GCCGAACCGG GTTCGATCAT ATCGGTTACG


 


251
GCACGGTTGC GCCGCTGTTC GCTGTCTGCC CGGCCGGGCC TGTTGGGATC


 


301
GTAGGCGGGC GTATTGGCCA AGGCGAGGAT TTCCCCCGTG CGGGCATCCA


 


351
ArACCACCAC CGTTCCGGCT TTTGCCTGAT GGTATTCGAC CGCCTTGTTC


 


401
AACTCTTCAT AGGCCAAGGT CTGAATCCTC TGATCGAGGG AAAGGATGAT


 


451
GTCTTTGCCG TTTTTCGGGG CTTTAkTGCG CGGGGAGTCC AAGCTGTCCA


 


501
CAATATTGCC CTGCCGGTCC CGCAAAACGA CTTCCGCGCC GTCTTCGCCA


 


551
TGCAAGCTGT CTTCAAGCGA AAGTTCCAAA CCTTCCTGAC CTTTGCCGTC


 


601
AATATCGGTA AATCCGATGA CGTGTGCAAA CAGGTTGCCC ATCGGGTAAT


 


651
GGCGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 902; ORF 240>:










m240.pep




1
MIEVIHFFGT ETRRQFACAD VGRFLHDAAH IQRGVNMGIA HGRRSDFIRL


 


51
RIQPFVQIGF ARIQCLRNHK RFDCRTGFDH IGYGTVAPLF AVCPAGPVGI


 


101
VGGRIGQGED FPRAGIQXHH RSGFCLMVFD RLVQLFIGQG LNPLIEGKDD


 


151
VFAVFRGFXA RGVQAVHNIA LPVPQNDFRA VFAMQAVFKR KFQTFLTFAV


 


201
NIGKSDDVCK QVAHRVMAF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 240 shows 94.5% identity over a 220 aa overlap with a predicted ORF (ORF 240.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 903>:










a240.seq




1
ATGATAGAAG TCATACATTT CTTCGGCACC GAAACGCGCA GACAGTTTGC


 


51
TTGTGCCGAC GTTGGACGAT TTCTGCATGA TGCCGCGCAC ATCCAAAGAG


 


101
GGGTAAACAT GGGTATCGCG CACGGGAGAC GGTCCGATTT TATAAGGCTG


 


151
CGTATTCAGC CGTTCGTTCA AATCGGTTTT GCCCGCATCC AATGCCTTCG


 


201
CAATCACAAA CGGTTTGATT GCCGAACCGG GTTCGATCAT ATCGGTTACG


 


251
GCACGGTTGC GCCGCTGTTC GCTGTCTGCC CGGCCGGGCC TGTTGGGATC


 


301
GTAGGCGGGC GTATTGGCCA AGGCGAGGAT TTCCCCCGTG CGGGCATCCA


 


351
AAACCACCAC CGTTCCGGCT TTTGCCTGAT GGTATTCGAC CGCCTTGTTC


 


401
AACTCTTCAT AGGCCAAGGT CTGAATCCTC TGATCGAGGG AAAGGATGAT


 


451
GTCTTTGCCG TTTTTCGGGG CTTTATTGCG CGGGGAGTCC AAGCTGTCCA


 


501
CAATATTGCC CTGCCGGTCC CGCAAAACGA CTTCCGCGCC GTCTTCGCCA


 


551
TGCAGGCTGT CTTCAAGCGA AAGTTCCAAA CCTTCCTGAC CTTTGCCGTC


 


601
AATATCGGTA AATCCGATGA CGTGTGCAAA CAGGTTGCCC ATCGGGTAAT


 


651
GGCGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 904; ORF 240.a>:










a240.pep




1
MIEVIHFFGT ETRRQFACAD VGRFLHDAAH IQRGVNMGIA HGRRSDFIRL


 


51
RIQPFVQIGF ARIQCLRNHK RFDCRTGFDH IGYGTVAPLF AVCPAGPVGI


 


101
VGGRIGQGED FPRAGIQNHH RSGFCLMVFD RLVQLFIGQG LNPLIEGKDD


 


151
VFAVFRGFIA RGVQAVHNIA LPVPQNDFRA VFAMQAVFKR KFQTFLTFAV


 


201
NIGKSDDVCK QVAHRVMAF*






m240/a240 99.1% identity in 219 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 905>:










g241.seq




1
ATGATAGAAG TCATACATTT CTTCGGCACC GAAACGCGCA GACAGTTTGC


 


51
TTGTGCCGAC GTTGGACGAT TTCTGCATGA TGCCGCGCAC ATCCAAAGAG


 


101
GGGTAAACAT GGGTATCGCG CACGGGAGAC GGTCCGATTT TATAAGGCTG


 


151
CGTATTCAGC CGTTCGTTCA AATCGGTTTT GCCCGCATCC AATGCCTTCG


 


201
CAATCACAAA CGGTTTGATT GCCGAACCGG GTTCGATCAT ATCGGTTACG


 


251
GCACGGTTGC GCCGCTGTTC GCTGTCTGCC CGGCCGGGCC TGTTGGGATC


 


301
GTAGGCGGGC GTATTGGCCA AGGCGAGGAT TTCCCCCGTG CGGGCATCCA


 


351
ArACCACCAC CGTTCCGGCT TTTGCCTGAT GGTATTCGAC CGCCTTGTTC


 


401
AACTCTTCAT AGGCCAAGGT CTGAATCCTC TGATCGAGGG AAAGGATGAT


 


451
GTCTTTGCCG TTTTTCGGGG CTTTAkTGCG CGGGGAGTCC AAGCTGTCCA


 


501
CAATATTGCC CTGCCGGTCC CGCAAAACGA CTTCCGCGCC GTCTTCGCCA


 


551
TGCAAGCTGT CTTCAAGCGA AAGTTCCAAA CCTTCCTGAC CTTTGCCGTC


 


601
AATATCGGTA AATCCGATGA CGTGTGCAAA CAGGTTGCCC ATCGGGTAAT


 


651
GGCGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 906; ORF 241.ng>:










g241.pep




1
MPTRPTRAAN PPTPTTWLQT AYCPRPPYRP PSVQTHTPHE PASSTCAAKS


 


51
ANRRENSHNA QPTYLLHPSN KMPSETEQTL FRRHQIPPSC RQSVVVMTVR


 


101
TVDMTVCDFL IGCIAHAFNR SFKADFHACQ RMVAVHHRLA VGNIGYTIDD


 


151
NIAGFRIVRF KHHTDLDFNR ERARIFNTDQ LRIMLTERIV GRKRHFDRIA


 


201
GILTVQRLFH QRENAVVTAV QIRNRFFGFI QKLIVGIIHL IMQRNHGIFC


 


251
NSHICPFRNS RLITGAF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 907>:










m241.seq (partial)











1
..CGGCAATCAG TGGTGGTGAT GACCGTGCGG GCCGTGGACA TGACCGTGTG



 


51
  CGATTTCCTC ATCGGATGCA TCGCGCACGC TTTCAACTGT AGCCTTAAAG


 


101
  CGGATTTTCA TGCCTGCCAA AGGATGGTTG CCGTCCACCA CCGCCTTGCC


 


151
  GTCGGCAACA TCGGTTACAC GATAGACGAC AACATCGCCG GTTTCAGGAT


 


201
  CGTCGGCTTC AAACATCATG CCGACTTCGA CTTCAACAGG GAACACGCCC


 


251
  GCATCTTCGA TACGGACCAA CTCCGGATCC TGCTCGCCGA ACGCATCGTC


 


301
  GGGCGACAGC GCCACATCGA CCGTATCGCC GGCATCCTTA CCGTGCAACG


 


351
  CCTCTTCCAC CAAAGGGAAA ATGCCGTCGT AACCGCCGTG CAGATACGCA


 


401
  ATCGGTTCTT CGGTTTTGTC CAAAAGCTGA TTGTTGGCAT CATACATCTC


 


451
  ATAATGCAGC GAAACCACGG AATTTTTCAC GATAGCCATA TTTGTCCTTT


 


501
  CAGGAACAGC AGATTAATTA CAGGCGCATT CTAA






This corresponds to the amino acid sequence <SEQ ID 908; ORF 241>:









m241.pep (partial)










1
..RQSVVVMTVR AVDMTVCDFL IGCIAHAFNC SLKADFHACQ RMVAVHHRLA



 


51
  VGNIGYTIDD NIAGFRIVGF KHHADFDFNR EHARIFDTDQ LRILLAERIV


 


101
  GRQRHIDRIA GILTVQRLFH QRENAVVTAV QIRNRFFGFV QKLIVGIIHL


 


151
  IMQRNHGIFH DSHICPFRNS RLITGAF*






Computer analysis or this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 241 shows 91.5% identity over a 177 aa overlap with a predicted ORF (ORF 241.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 909>:










a241.seq




1
ATGCCAACAC GTCCAACTCG CGCCGCAAAG CATCCAACCC CGCCAACCTG


 


51
GCTTCAGACG GCATACTGCC CTCGTCCGCC ATATCGTCCG CCGTCCGTGC


 


101
AAACGCATAC ACCGCATGAA CCGGCTTCCT CAACCTGCGC GGCAAAATCA


 


151
GCGAACCGAC GGGAAAATTT TCATAATGCC CAACCGACAT ACCTTCTCCA


 


201
TCCATCAAAC AAAATGCCGT CTGAAATGGA ACAAACCCTT TTCAGACGGC


 


251
ATCAGATACC TCCAAGCTGC CGGCAATCAG TGGTGGTGAT GACCGTGCGG


 


301
ACCGTGGACA TGACCGTGTG CGATTTCCTC ATCGGATGCA TCGCGCACAC


 


351
TTTCAACCGT AGCCTTAAAG CGGATTTTCA TGCCTGCCAA AGGATGGTTG


 


401
CCGTCCACCA CCGCCTTACC GTCGGCAACA TCGGTTACAC GATAGACGAC


 


451
AACATCGCCG GTTTCAGGAT CGTCGGCTTC AAACATCATG CCGACTTCGA


 


501
CTTCAACAGG GAACACGCCC GCATCTTCAA TACGGACCAA CTCCGGATCC


 


551
TGCTCGCCGA ACGCATCGTC GGGCGAAAGC GCCACATCGA CCGTATCGCC


 


601
GGCATCCTTA CCGTGCAACG CCTCTTCCAC CAAAGGGAAA ATGCCGTCGT


 


651
AACCGCCGTG CAGATACGCA ATCGGTTCTT CGGTTTTGTC CAAAAGCTGA


 


701
TTGTTGGCAT CATACATCTC ATAATGCAGC GAAACCACGG AATTCTTCAC


 


751
GATAGCCATA TTTGTCCTTT CAGGAACAGC AGATTAATTA CAGGCGCATT


 


801
CTAA






This corresponds to the amino acid sequence <SEQ ID 910; ORF 241.a>:










a241.pep




1
MPTRPTRAAK HPTPPTWLQT AYCPRPPYRP PSVQTHTPHE PASSTCAAKS


 


51
ANRRENFHNA QPTYLLHPSN KMPSEMEQTL FRRHQIPPSC RQSVVVMTVR


 


101
TVDMTVCDFL IGCIAHTFNR SLKADFHACQ RMVAVHHRLT VGNIGYTIDD


 


151
NIAGFRIVGF KHHADFDFNR EHARIFNTDQ LRILLAERIV GRKRHIDRIA


 


201
GILTVQRLFH QRENAVVTAV QIRNRFFGFV QKLIVGIIHL IMQRNHGILH


 


251
DSHICPFRNS RLITGAF*






m241/a241 96.0% identity in 177 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 911>:










g241-1.seq




1
ATGATAGAAG TCATACATTT CTTCGGCACC GAAACGCGCA GACAGTTTGC


 


51
TTGTGCCGAC GTTGGACGAT TTCTGCATGA TGCCGCGCAC ATCCAAAGAG


 


101
GGGTAAACAT GGGTATCGCG CACGGGAGAC GGTCCGATTT TATAAGGCTG


 


151
CGTATTCAGC CGTTCGTTCA AATCGGTTTT GCCCGCATCC AATGCCTTCG


 


201
CAATCACAAA CGGTTTGATT GCCGAACCGG GTTCGATCAT ATCGGTTACG


 


251
GCACGGTTGC GCCGCTGTTC GCTGTCTGCC CGGCCGGGCC TGTTGGGATC


 


301
GTAGGCGGGC GTATTGGCCA AGGCGAGGAT TTCCCCCGTG CGGGCATCCA


 


351
ArACCACCAC CGTTCCGGCT TTTGCCTGAT GGTATTCGAC CGCCTTGTTC


 


401
AACTCTTCAT AGGCCAAGGT CTGAATCCTC TGATCGAGGG AAAGGATGAT


 


451
GTCTTTGCCG TTTTTCGGGG CTTTAkTGCG CGGGGAGTCC AAGCTGTCCA


 


501
CAATATTGCC CTGCCGGTCC CGCAAAACGA CTTCCGCGCC GTCTTCGCCA


 


551
TGCAAGCTGT CTTCAAGCGA AAGTTCCAAA CCTTCCTGAC CTTTGCCGTC


 


601
AATATCGGTA AATCCGATGA CGTGTGCAAA CAGGTTGCCC ATCGGGTAAT


 


651
GGCGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 912; ORF 241-1.ng>:










g241-1.pep




1
MPTRPTRAAN PPTPTTWLQT AYCPRPPYRP PSVQTHTPHE PASSTCAAKS


 


51
ANRRENSHNA QPTYLLHPSN KMPSETEQTL FRRHQIPPSC RQSVVVMTVR


 


101
TVDMTVCDFL IGCIAHAFNR SFKADFHACQ RMVAVHHRLA VGNIGYTIDD


 


151
NIAGFRIVRF KHHTDLDFNR ERARIFNTDQ LRIMLTERIV GRKRHFDRIA


 


201
GILTVQRLFH QRENAVVTAV QIRNRFFGFI QKLIVGIIHL IMQRNHGIFC


 


251
NSHICPFRNS RLITGAF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 913>:










m241-1.seq




1
ATGCCAACAC GTCCAACTCG CGCTGCAAAC CCTCCAACCC CGCCAACCTG


 


51
GCTTCAGACG GCATACTGCC CTCGTCCGCC ATATCGTCCG CCGTCCGTGC


 


101
AAACGCGTAC ACCGCGTGAA CCGGCTTCCT CAACCTGCGC GGCAAAATCA


 


151
GCGAACCGAC GGGAAAATTC TCATAATGCC CAACCGACAT ACCTTCTCCA


 


201
TCCATCAAAC AAAATGCCGT CTGAAACGGA ACAAACCCTT TTCAGACGGC


 


251
ATCAGATACC TCCAAGCTGC CGGCAATCAG TGGTGGTGAT GACCGTGCGG


 


301
GCCGTGGACA TGACCGTGTG CGATTTCCTC ATCGGATGCA TCGCGCACGC


 


351
TTTCAACTGT AGCCTTAAAG CGGATTTTCA TGCCTGCCAA AGGATGGTTG


 


401
CCGTCCACCA CCGCCTTGCC GTCGGCAACA TCGGTTACAC GATAGACGAC


 


451
AACATCGCCG GTTTCAGGAT CGTCGGCTTC AAACATCATG CCGACTTCGA


 


501
CTTCAACAGG GAACACGCCC GCATCTTCGA TACGGACCAA CTCCGGATCC


 


551
TGCTCGCCGA ACGCATCGTC GGGCGACAGC GCCACATCGA CCGTATCGCC


 


601
GGCATCCTTA CCGTGCAACG CCTCTTCCAC CAAAGGGAAA ATGCCGTCGT


 


651
AACCGCCGTG CAGATACGCA ATCGGTTCTT CGGTTTTGTC CAAAAGCTGA


 


701
TTGTTGGCAT CATACATCTC ATAATGCAGC GAAACCACGG AATTTTTCAC


 


751
GATAGCCATA TTTGTCCTTT CAGGAACAGC AGATTAATTA CAGGCGCATT


 


801
CTAA






This corresponds to the amino acid sequence <SEQ ID 914; ORF 241-1>:










m241-1.pep




1
MPTRPTRAAN PPTPPTWLQT AYCPRPPYRP PSVQTRTPRE PASSTCAAKS


 


51
ANRRENSHNA QPTYLLHPSN KMPSETEQTL FRRHQIPPSC RQSVVVMTVR


 


101
AVDMTVCDFL IGCIAHAFNC SLKADFHACQ RMVAVHHRLA VGNIGYTIDD


 


151
NIAGFRIVGF KHHADFDFNR EHARIFDTDQ LRILLAERIV GRQRHIDRIA


 


201
GILTVQRLFH QRENAVVTAV QIRNRFFGFV QKLIVGIIHL IMQRNHGIFH


 


251
DSHICPFRNS RLITGAF*






m241-1/g241-1 93.3% identity in 267 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 915>:










a241-1.seq




1
ATGCCAACAC GTCCAACTCG CGCCGCAAAG CATCCAACCC CGCCAACCTG


 


51
GCTTCAGACG GCATACTGCC CTCGTCCGCC ATATCGTCCG CCGTCCGTGC


 


101
AAACGCATAC ACCGCATGAA CCGGCTTCCT CAACCTGCGC GGCAAAATCA


 


151
GCGAACCGAC GGGAAAATTT TCATAATGCC CAACCGACAT ACCTTCTCCA


 


201
TCCATCAAAC AAAATGCCGT CTGAAATGGA ACAAACCCTT TTCAGACGGC


 


251
ATCAGATACC TCCAAGCTGC CGGCAATCAG TGGTGGTGAT GACCGTGCGG


 


301
ACCGTGGACA TGACCGTGTG CGATTTCCTC ATCGGATGCA TCGCGCACAC


 


351
TTTCAACCGT AGCCTTAAAG CGGATTTTCA TGCCTGCCAA AGGATGGTTG


 


401
CCGTCCACCA CCGCCTTACC GTCGGCAACA TCGGTTACAC GATAGACGAC


 


451
AACATCGCCG GTTTCAGGAT CGTCGGCTTC AAACATCATG CCGACTTCGA


 


501
CTTCAACAGG GAACACGCCC GCATCTTCAA TACGGACCAA CTCCGGATCC


 


551
TGCTCGCCGA ACGCATCGTC GGGCGAAAGC GCCACATCGA CCGTATCGCC


 


601
GGCATCCTTA CCGTGCAACG CCTCTTCCAC CAAAGGGAAA ATGCCGTCGT


 


651
AACCGCCGTG CAGATACGCA ATCGGTTCTT CGGTTTTGTC CAAAAGCTGA


 


701
TTGTTGGCAT CATACATCTC ATAATGCAGC GAAACCACGG AATTCTTCAC


 


751
GATAGCCATA TTTGTCCTTT CAGGAACAGC AGATTAATTA CAGGCGCATT


 


801
CTAA






This corresponds to the amino acid sequence <SEQ ID 916; ORF 241-1.a>:










a241-1.pep




1
MPTRPTRAAK HPTPPTWLQT AYCPRPPYRP PSVQTHTPHE PASSTCAAKS


 


51
ANRRENFHNA QPTYLLHPSN KMPSEMEQTL FRRHQIPPSC RQSVVVMTVR


 


101
TVDMTVCDFL IGCIAHTFNR SLKADFHACQ RMVAVHHRLT VGNIGYTIDD


 


151
NIAGFRIVGF KHHADFDFNR EHARIFNTDQ LRILLAERIV GRKRHIDRIA


 


201
GILTVQRLFH QRENAVVTAV QIRNRFFGFV QKLIVGIIHL IMQRNHGILH


 


251
DSHICPFRNS RLITGAF*






m241-1/a241-1 95.1% identity in 267 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 917>:










g242.seq




1
atgatcggcg aacttgttgt tttgttcgtg atcgagcact tcaagcaacg


 


51
cgctggcggg atcgccccga aagtcgctgc ccaatttgtc gatttcgtcg


 


101
agcaggaaca acgggtttct tacgcctgct tttgccatat tctgcaaaat


 


151
cttgccgggc atagagccga tataggtacg gcggtgcccg cggatttcgc


 


201
tttcgtcgcg cacgccgccc aaggccatac ggacatattt ccgccccgtt


 


251
gctttggcga tggattcgcc caaagaggtt ttgcccacgc ccggagggcc


 


301
gaccaaacac agaatcggac ctttgagctt gtccatacgt ttttggacgg


 


351
cgaggtattc caaaatccgt tctttgactt tttccaggcc gtagtggtcg


 


401
gcatccagca ccagtccggc tttggcgatg tctttgctga cgcgggattt


 


451
tttcttccac ggcagtccga gcagggtgtc gatgtagttg cgtacgacgg


 


501
tggattcggc agacatcggc ggcatcattt tgagtttttt cagttcggac


 


551
aggcattttt cttccgcttc tttggtcata cccgcctttt tgatgcctgc


 


601
ctccaaggca tccagttcgc cgttttcgtc ttcttcgccc aattctttgt


 


651
gtatcgcttt aatctgttcg ttcagataat attcgcgttg ggatttttcc


 


701
atttggcgtt tgacgcgtcc gcgtatgcgt ttttcggcct gcataatgtc


 


751
gagttcggat tccagctttg ccagcaggaa ttccatccgt ttgccgattt


 


801
cgggaatctc caaaatctgt tggcgttgcg ccagtttcaa ctgcaaatgc


 


851
gctgcgaccg tatcggttag






This corresponds to the amino acid sequence <SEQ ID 918; ORF 242.ng>:










g242.pep




1
MIGELVVLFV IEHFKQRAGG IAPKVAAQFV DFVEQEQRVS YACFCHILQN


 


51
LAGHRADIGT AVPADFAFVA HAAQGHTDIF PPRCFGDGFA QRGFAHARRA


 


101
DQTQNRTFEL VHTFLDGEVF QNPFFDFFQA VVVGIQHQSG FGDVFADAGF


 


151
FLPRQSEQGV DVVAYDGGFG RHRRHHFEFF QFGQAFFFRF FGHTRLFDAC


 


201
LQGIQFAVFV FFAQFFVYRF NLFVQIIFAL GFFHLAFDAS AYAFFGLHNV


 


251
EFGFQLCQQE FHPFADFGNL QNLLALRQFQ LQMRCDRIG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 919>:










m242.seq




1
ATGATCGGCA AACTTGTTGT TTTGTTCGGG ATCGAGCACT TCGAGCAACG


 


51
CGCTGGCGGG ATCGCCTCGG AAGTCGTTAC CCAATTTGTC GATTTCGTCG


 


101
AGCAGGAACA AGGGGTTTTT CACGCCGGCT TTTGCCATAT TCTGCAAAAT


 


151
CTTACCGGGC ATAGAGCCGA TATAGGTGCG GCGGTGTCCC CTGATTTCGC


 


201
TTTCGTCGCG CACGCCGCCC AAAGCCATGC GGACATATTT CCGCCCCGTT


 


251
GCTTTGGCGA TGGATTCGCC CAAAGAGGTT TTGCCCACGC CCGGAGGGCC


 


301
GACCAGGCAC AGAATCGGGC CTTTGAGTTT GTCCATACGT TTTTGGACGG


 


351
CGAGGTATTC CAAAATCCGT TCTTTGACTT TTTCCAGGCC GTAGTGGTCG


 


401
GCATCCAGCA CCAGTCCGGC TTTGGCGATG TCTTTGCTGA CGCGGGATTT


 


451
TTTCTTCCAC GGCAGCTCGA GCAAAGTGTC GATGTAGTTG CGTACGACGG


 


501
TGGATTCCGC AGACATCGGT GGCATCATTT TGAGCTTTTT CAGTTCGGAC


 


551
AGGCATTTTT CTTCCGCTTC TTTGGTCATA CCCGCCTTTT TGATATCTGC


 


601
TTCCAAGGCA TCCAGTTCGC CGTTTTCGTC TTCTTCGCCC AGTTCTTTGT


 


651
GTATCGCTTT AATCTGTTCG TTCAGATAAT ATTCGCGCTG GGATTTTTCC


 


701
ATTTGGCGTT TGACGCGTCC GCGTATGCGT TTTTCGGCCT GCATAATGTC


 


751
GAGTTCGGAT TCCAGCTGTG CCAGCAGGAA TTCCATCCGT TTGCCGATTT


 


801
CGGGAATTTC CAAAATCTGT TGGCGTTGCG CCAGTTTCAA CTGCAAATGC


 


851
GCTGCGACCG TATCGGTTAG






This corresponds to the amino acid sequence <SEQ ID 920; ORF 242>:










m242.pep




1
MIGKLVVLFG IEHFEQRAGG IASEVVTQFV DFVEQEQGVF HAGFCHILQN


 


51
LTGHRADIGA AVSPDFAFVA HAAQSHADIF PPRCFGDGFA QRGFAHARRA


 


101
DQAQNRAFEF VHTFLDGEVF QNPFFDFFQA VVVGIQHQSG FGDVFADAGF


 


151
FLPRQLEQSV DVVAYDGGFR RHRWHHFELF QFGQAFFFRF FGHTRLFDIC


 


201
FQGIQFAVFV FFAQFFVYRF NLFVQIIFAL GFFHLAFDAS AYAFFGLHNV


 


251
EFGFQLCQQE FHPFADFGNF QNLLALRQFQ LQMRCDRIG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 242 shows 90.3% identity over a 289 aa overlap with a predicted ORF (ORF 242.ng) from N. gonorrhoeae: 

m242/g24290.3% identity in 289 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 921>:










a242.seq




1
ATGATCGGCG AACTTGTTGT TTTGCTCGGG ATCAAGCACT TCGAGCAACG


 


51
CGCTGGCGGG ATCGCCCCGG AAGTCGCTAN CCAATTTGTC GATTTCGTCG


 


101
AGCAGGAACA ATGGGTTTTT TACGCCGGCT TTTGCCATAT TCTGCAAAAT


 


151
CTTACCGGGC ATGGAGCCGA TATAGGTGCG GCGGTGTCCC CGGATTTCGC


 


201
TTTCGTCGCG CACGCCGCCC AAAGCCATGC GGACATATTT CCGCCCCGTT


 


251
GCTTTGGCGA TGGATTCGCC CAAAGAGGTT TTGCCCACGC CTGGAGGGCC


 


301
GACCAGGCAC AGAATCGGGC CTTTGAGTTT GTCCATACGT TTTTGGACGG


 


351
CGAGGTATTC CAAAATCCGT TCTTTGACTT TTTCCAGGCC GTAGTGGTCG


 


401
GTATCCAGCA CCAATCCGGC TTTGGCGATG TCTTTGCTGA CGCGGGATTT


 


451
TTTCTTCCAC GGCAGTTCGA GCAGGGTGTC GATGTAGTTG CGTACGACGG


 


501
TGGATTCGGC AGACATCGGC GGCATCATTT TGAGCTTTTT CAGTTCGGAC


 


551
AGGCATTTTT CTTCCGCTTC TTTGGTCATA CCCGCCTTTT TGATATCTGC


 


601
TTCCAAGGCA TCCAGTTCGC CGTTTTCGTC TTCTTCGCCC AGTTCTTTGT


 


651
GTATCGCTTT AATCTGTTCG TTCAGATAAT ATTCGCGCTG GGATTTTTCC


 


701
ATTTGGCGTT TGACGCGTCC GCGTATGCGT TTTTCGGCCT GCATAATGTC


 


751
GAGTTCGGAT TCCAGCTGTG CCAGCAGGAA TTCCATCCGT TTGCCGATTT


 


801
CGGGAATTTC CAAAATCTGT TGGCGTTGCG CCAGTTTCAA CTGCAAATGC


 


851
GCTGCGACCG TATCGGTTAG






This corresponds to the amino acid sequence <SEQ ID 922; ORF 242.a>:










a242.pep




1
MIGELVVLLG IKHFEQRAGG IAPEVAXQFV DFVEQEQWVF YAGFCHILQN


 


51
LTGHGADIGA AVSPDFAFVA HAAQSHADIF PPRCFGDGFA QRGFAHAWRA


 


101
DQAQNRAFEF VHTFLDGEVF QNPFFDFFQA VVVGIQHQSG FGDVFADAGF


 


151
FLPRQFEQGV DVVAYDGGFG RHRRHHFELF QFGQAFFFRF FGHTRLFDIC


 


201
FQGIQFAVFV FFAQFFVYRF NLFVQIIFAL GFFHLAFDAS AYAFFGLHNV


 


251
EFGFQLCQQE FHPFADFGNF QNLLALRQFQ LQMRCDRIG*






m242/a242 95.2% identity in 289 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 923>:










g243.seq




1
ATGGTaatcg tctGGTTGCc cgAGTTaccg CCGATGCCGG CGACGATGGG


 


51
CATCAGCGCG GCGAGTGCGA CGATTTTTTC gatactgcCT TCAAACGCGC


 


101
CGATGACGCG GCTGGCGAGG AAGGCGGTGC AGAGGTTGAC GGCGAGCCAC


 


151
ATCCAGCGGT TTTTGACGGA ATCCAAGACG GGGGCGAACA GGTCTTCCTC


 


201
TTCCTGCAAA CCTGCCATGT TCAACATATC CGCTTCGGAT TCTTCGCGGA


 


251
TCACGTCCAC CATCTCGTCG ATGGTAATCc tgCCGATGAG CTTTTTGTTT


 


301
TCATCAACGA CGGGCGCGGT AACCAAGTCG TAG






This corresponds to the amino acid sequence <SEQ ID 924; ORF 243.ng>:










g243.pep




1
MVIVWLPELP PMPATMGISA ASATIFSILP SNAPMTRLAR KAVQRLTASH


 


51
IQRFLTESKT GANRSSSSCK PAMFNISASD SSRITSTISS MVILPMSFLF


 


101
SSTTGAVTKS *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 925>:










m243.seq




1
ATGGTAATCG TCTGGTTGCC CGAGTTACCG CCTATGCCGG CGACGATGGG


 


51
CATCAGCGCG GyGAGTGCGA CGATTTTTTC GATGCTGCCT TCAAACGCGC


 


101
CGATAACACG GyTGGCGAGG AAGGCGGTGC AGAGGTTGAC GGCGAGCCAC


 


151
ATCCAGyGGT TTTTCACCGA ATCCCACACG GGGGCGAAyA GGTCTTCCTC


 


201
TTCCTGCAAA CCCGCCATAT TCAGCATATC CGCTTCCGAT TCTTCGCGGA


 


251
TCACGTCCAC CATCTCGTCG ATGGTAATCC TGCCGATGAG CTTTTTGTTT


 


301
TCATCGACGA CGGGCGCGGT AACCAAGTCG TAG






This corresponds to the amino acid sequence <SEQ ID 926; ORF 243>:










m243.pep




1
MVIVWLPELP PMPATMGISA XSATIFSMLP SNAPITRLAR KAVQRLTASH


 


51
IQXFFTESHT GANRSSSSCK PAIFSISASD SSRITSTISS MVILPMSFLF


 


101
SSTTGAVTKS *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 243 shows 92.7% identity over a 110 aa overlap with a predicted ORF (ORF 243.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 927>:










a243.seq




1
ATGGTAATCG TCTGGTTGCC CGAGTTACCG CCTATGCCGG CGACGATGGG


 


51
CATCAGCGCG GCGAGTGCGA CGATTTTTTC GATGCTGCCT TCAAACGCGC


 


101
CGATAACACG GCTGGCGAGG AAGGCGGTGC AGAGGTTGAC GGCGAGCCAC


 


151
ATCCAGCGGT TTTTGACGGA ATCCAAGACG GGGGCGAATA AGTCTTCCTC


 


201
TTCTTGCAAA CCCGCCATAT TCAACATATC CGCTTCGGAT TCTTCGCGGA


 


251
TCACGTCCAC CATTTCGTCA ACGGTCACCC TGCCGATGAG CTTTTTGTTT


 


301
TCATCGACGA CGGGCGCGGT AACCAAGTCA TAG






This corresponds to the amino acid sequence <SEQ ID 928; ORF 243.a>:










a243.pep




1
MVIVWLPELP PMPATMGISA ASATIFSMLP SNAPITRLAR KAVQRLTASH


 


51
IQRFLTESKT GANKSSSSCK PAIFNISASD SSRITSTISS TVTLPMSFLF


 


101
SSTTGAVTKS *






m243/a243 92.7% identity in 110 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 929>:










g244.seq




1
atgccgcctg aagcccggcc ggcgggttca gacggcattg ccgctttact


 


51
tcgatcggtt tatacgcaaa acgcgcttca ggaaataaat cagattattc


 


101
cccagacgcc ttcaggcttc cttccgtgcc accgtaacca tagccgggcg


 


151
caacacacgg tcggacaggg tataaccctt cttcatcaca ccaaccacgg


 


201
tattgggttc ctgctcactg gccaccgcct gcatcgcctg atggatattc


 


251
ggatcgagct tatcgcccgc tttaggattg atttccttga tttgcgtggc


 


301
atcaaacgcc ttctgcaact cattcaaagt catctgcaca cccattttca


 


351
gcgcatcgaa attaccgctc tgatccaaaa gcgccatttc cagataatcc


 


401
ttgaccggca acatttccac ggcaaacttc tgtccggcga acttgtgcgt


 


451
atcggcaatt tcctgctggt ggcggcggcg caggttttgc tcgtttgcca


 


501
aagcgcgcag ttgttcgtct ttcaactgcg cttccagctc ggcaatccgc


 


551
gcctgcaaat cctcataagc cggctcggcg gcagcctgtt cctgtacacc


 


601
gtccgcattt cctactgtct cgacggtttc caccgcctcc acattttcaa


 


651
ccgcttcttc actgttttgc tgctgtgtct gttcgctcat atcgtatccc


 


701
tcaaaacaaa ttggaaatca aaatccggtt attacccgag caagataagg


 


751
acattttcaa gaaacttcaa gcaaaggcag gaaatttcac atccgccgcc


 


801
gaatacccta ccgcaaaaac catataaacg gtaa






This corresponds to the amino acid sequence <SEQ ID 930; ORF 244.ng>:










g244.pep




1
MPPEARPAGS DGIAALLRSV YTQNALQEIN QIIPQTPSGF LPCHRNHSRA


 


51
QHTVGQGITL LHHTNHGIGF LLTGHRLHRL MDIRIELIAR FRIDFLDLRG


 


101
IKRLLQLIQS HLHTHFQRIE ITALIQKRHF QIILDRQHFH GKLLSGELVR


 


151
IGNFLLVAAA QVLLVCQSAQ LFVFQLRFQL GNPRLQILIS RLGGSLFLYT


 


201
VRISYCLDGF HRLHIFNRFF TVLLLCLFAH IVSLKTNWKS KSGYYPSKIR


 


251
TFSRNFKQRQ EISHPPPNTL PQKPYKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 931>:










m244.seq




1
ATGCCGTCTG AAGCCCGACA GGCGGGTTCA GACGGCATTG CCGCTTTACT


 


51
TCGATCGGTT TATACGCAAA ACGCGCTTCA GGAAATAAAT CAGATTATTC


 


101
CCCAGACGCC TTCAGGCTTC CTTCTGCGCC ACCGTAACCA TAGCCGGGCG


 


151
CAACACGCGG TCGGACAGCG TATAACCCTT CTTCATCACA CCCACCACGG


 


201
TATTCGGCTC CTGTTCGCTT GCCACCGCCT GCATCGCCTG ATGGATATTC


 


251
GGATCGAGCT TATCGCCCGC TTTAGGGTTG ATTTCCTTGA TTTGCGTAGC


 


301
ATCAAATGCT TTCTGCAACT CGTTCAAAGT CATCTGCACG CCCATTTTCA


 


351
GCGCATCGAA ATTGCCGCTC TGATCCAAAA GCGCCATTTC CAGATAATCC


 


401
TTGACCGGCA GCATTTCCAC GGCAAACTTC TGTCCGGCGA ACTTGTGCGT


 


451
ATCCGCAATT TyCTGCTGGT GGCGGCGGCG CAGGTTTTGC TCGTTTGCCA


 


501
AAGCGCGCTG CTCGTCTTTC AACTGCGTTT CCAGCTCGGC AATCCGCGCC


 


551
TGCAAATCCT CATAAGCCGG CTCTGCGGCA GCCTGTTCCT GCACACCGTC


 


601
CGCATTTCCT ACTGTTTCGA CGGTTTCCAC CGCCTCCACA TTTTCAACCG


 


651
CTTCTTCACT GTTTTGCTGC TGTGTCTGTT CGCTCATATC GTATCCCTTA


 


701
AAACAAATTG GAAATCAAAA TCCAGTTATT ACCCGCGCAA GATAAGGACA


 


751
TTTTCAAGAA ACTTCAAkCA AAAkCAGAGA ATTTCAAATT CATTTTCAAA


 


801
TCCCCTACCG AAAAAATAAT ATAGACGGTA A






This corresponds to the amino acid sequence <SEQ ID 932; ORF 244>:










m244.pep




1
MPSEARQAGS DGIAALLRSV YTQNALQEIN QIIPQTPSGF LLRHRNHSRA


 


51
QHAVGQRITL LHHTHHGIRL LFACHRLHRL MDIRIELIAR FRVDFLDLRS


 


101
IKCFLQLVQS HLHAHFQRIE IAALIQKRHF QIILDRQHFH GKLLSGELVR


 


151
IRNFLLVAAA QVLLVCQSAL LVFQLRFQLG NPRLQILISR LCGSLFLHTV


 


201
RISYCFDGFH RLHIFNRFFT VLLLCLFAHI VSLKTNWKSK SSYYPRKIRT


 


251
FSRNFXQXQR ISNSFSNPLP KKXYRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 244 shows 86.3% identity over a 277 aa overlap with a predicted ORF (ORF 244.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 933>:










a244.seq




1
ATGCCGTCTG AAGCCCGACA GGCGGGTTCA GACGGCATTG CCGCTTTACT


 


51
TCGATCGGTT TATACGCAAA ACGCGCTTCA GGAAATAAAT CAGATTATTC


 


101
CCCAGACGCC TTCAGGCTTC CTTCTGTGCC ACCGTAACCA TAGCCGGGCG


 


151
CAACACGCGG TCGGACAGCG TATAACCCTT CTTCATCACG CCCACCACGG


 


201
TATTGGGTTC CTGTTCGCTT GCCACCGCCT GCATCGCCTG ATGGATATTC


 


251
GGATCGAGCT TATCGCCCGC TTTAGGATTG ATTTCCTTGA TTTGCGTAGC


 


301
ATCAAATGCT TTCTGCAACT CGTTCAAAGT CATCTGCACG CCCATTTTCA


 


351
GCGCATCGAA ATTGCCGCTC TGATCCAAAA GCGCCATTTC CAGATAATCC


 


401
TTGACCGGCA GCATTTCCAC GGCAAACTTC TGTCCGGCGA ACTTGTGCGT


 


451
ATCCGCAATT TCCTGCTGGT GGCGGCGGCG CAGGTTTTGC TCGTTTGCCA


 


501
AAGCGCGCAG CTGCTCGTCT TTCAACTGCG CTTCCAGCTC GGCAATCCGC


 


551
GCCTGCAAAT CCTCATAAGC CGGCTCTGCG GCAGCCTGTT CCTGCACACC


 


601
GTCCGCATTT CCTACTGTCT CGACGGTTTC CACCGCCTCC ACATTTTCAA


 


651
CCGCTTCTTC ACTGTTTTGC TGCTGTGTCT GTTCGCTCAT ATCGTATCCC


 


701
TTAAAACAAA TTGGAAATCA AAATCCAGTT ATTACCCGCG CAAGATAAGG


 


751
ACATTTTCAA GAAACTTCAA GCAAAGGCAG AGAATTTCAA ATTCATTTTC


 


801
AAATCCCCTA CCGAAAAAAT AATATAGACG GTAA






This corresponds to the amino acid sequence <SEQ ID 934; ORF 244.a>:










a244.pep




1
MPSEARQAGS DGIAALLRSV YTQNALQEIN QIIPQTPSGF LLCHRNHSRA


 


51
QHAVGQRITL LHHAHHGIGF LFACHRLHRL MDIRIELIAR FRIDFLDLRS


 


101
IKCFLQLVQS HLHAHFQRIE IAALIQKRHF QIILDRQHFH GKLLSGELVR


 


151
IRNFLLVAAA QVLLVCQSAQ LLVFQLRFQL GNPRLQILIS RLCGSLFLHT


 


201
VRISYCLDGF HRLHIFNRFF TVLLLCLFAH IVSLKTNWKS KSSYYPRKIR


 


251
TFSRNFKQRQ RISNSFSNPL PKK*YRR*






m244/a244 96.8% identity in 277 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 935>:










g244-1.seq




1
atgccgcctg aagcccggcc ggcgggttca gacggcattg ccgctttact


 


51
tcgatcggtt tatacgcaaa acgcgcttca ggaaataaat cagattattc


 


101
cccagacgcc ttcaggcttc cttccgtgcc accgtaacca tagccgggcg


 


151
caacacacgg tcggacaggg tataaccctt cttcatcaca ccaaccacgg


 


201
tattgggttc ctgctcactg gccaccgcct gcatcgcctg atggatattc


 


251
ggatcgagct tatcgcccgc tttaggattg atttccttga tttgcgtggc


 


301
atcaaacgcc ttctgcaact cattcaaagt catctgcaca cccattttca


 


351
gcgcatcgaa attaccgctc tgatccaaaa gcgccatttc cagataatcc


 


401
ttgaccggca acatttccac ggcaaacttc tgtccggcga acttgtgcgt


 


451
atcggcaatt tcctgctggt ggcggcggcg caggttttgc tcgtttgcca


 


501
aagcgcgcag ttgttcgtct ttcaactgcg cttccagctc ggcaatccgc


 


551
gcctgcaaat cctcataagc cggctcggcg gcagcctgtt cctgtacacc


 


601
gtccgcattt cctactgtct cgacggtttc caccgcctcc acattttcaa


 


651
ccgcttcttc actgttttgc tgctgtgtct gttcgctcat atcgtatccc


 


701
tcaaaacaaa ttggaaatca aaatccggtt attacccgag caagataagg


 


751
acattttcaa gaaacttcaa gcaaaggcag gaaatttcac atccgccgcc


 


801
gaatacccta ccgcaaaaac catataaacg gtaa






This corresponds to the amino acid sequence <SEQ ID 936; ORF 244-1.ng>:










g244-1.pep




1
MPPEARPAGS DGIAALLRSV YTQNALQEIN QIIPQTPSGF LPCHRNHSRA


 


51
QHTVGQGITL LHHTNHGIGF LLTGHRLHRL MDIRIELIAR FRIDFLDLRG


 


101
IKRLLQLIQS HLHTHFQRIE ITALIQKRHF QIILDRQHFH GKLLSGELVR


 


151
IGNFLLVAAA QVLLVCQSAQ LFVFQLRFQL GNPRLQILIS RLGGSLFLYT


 


201
VRISYCLDGF HRLHIFNRFF TVLLLCLFAH IVSLKTNWKS KSGYYPSKIR


 


251
TFSRNFKQRQ EISHPPPNTL PQKPYKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 937>:










m244-1.seq




1
ATGCCGTCTG AAGCCCGACA GGCGGGTTCA GACGGCATTG CCGCTTTACT


 


51
TCGATCGGTT TATACGCAAA ACGCGCTTCA GGAAATAAAT CAGATTATTC


 


101
CCCAGACGCC TTCAGGCTTC CTTCTGCGCC ACCGTAACCA TAGCCGGGCG


 


151
CAACACGCGG TCGGACAGCG TATAACCCTT CTTCATCACA CCCACCACGG


 


201
TATTCGGCTC CTGTTCGCTT GCCACCGCCT GCATCGCCTG ATGGATATTC


 


251
GGATCGAGCT TATCGCCCGC TTTAGGGTTG ATTTCCTTGA TTTGCGTAGC


 


301
ATCAAATGCT TTCTGCAACT CGTTCAAAGT CATCTGCACG CCCATTTTCA


 


351
GCGCATCGAA ATTGCCGCTC TGATCCAAAA GCGCCATTTC CAGATAATCC


 


401
TTGACCGGCA GCATTTCCAC GGCAAACTTC TGTCCGGCGA ACTTGTGCGT


 


451
ATCCGCAATT TyCTGCTGGT GGCGGCGGCG CAGGTTTTGC TCGTTTGCCA


 


501
AAGCGCGCTG CTCGTCTTTC AACTGCGTTT CCAGCTCGGC AATCCGCGCC


 


551
TGCAAATCCT CATAAGCCGG CTCTGCGGCA GCCTGTTCCT GCACACCGTC


 


601
CGCATTTCCT ACTGTTTCGA CGGTTTCCAC CGCCTCCACA TTTTCAACCG


 


651
CTTCTTCACT GTTTTGCTGC TGTGTCTGTT CGCTCATATC GTATCCCTTA


 


701
AAACAAATTG GAAATCAAAA TCCAGTTATT ACCCGCGCAA GATAAGGACA


 


751
TTTTCAAGAA ACTTCAAkCA AAAkCAGAGA ATTTCAAATT CATTTTCAAA


 


801
TCCCCTACCG AAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 938; ORF 244-1>:










m244-1.pep




1
MPSEARQAGS DGIAALLRSV YTQNALQEIN QIIPQTPSGF LLRHRNHSRA


 


51
QHAVGQRITL LHHTHHGIRL LFACHRLHRL MDIRIELIAR FRVDFLDLRS


 


101
IKCFLQLVQS HLHAHFQRIE IAALIQKRHF QIILDRQHFH GKLLSGELVR


 


151
IRNFLLVAAA QVLLVCQSAL LVFQLRFQLG NPRLQILISR LCGSLFLHTV


 


201
RISYCFDGFH RLHIFNRFFT VLLLCLFAHI VSLKTNWKSK SSYYPRKIRT


 


251
FSRNFXQXQR ISNSFSNPLP KK*






m244-1/G244-1 86.3% identity in 277 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 939>:










a244-1.seq




1
ATGCCGTCTG AAGCCCGACA GGCGGGTTCA GACGGCATTG CCGCTTTACT


 


51
TCGATCGGTT TATACGCAAA ACGCGCTTCA GGAAATAAAT CAGATTATTC


 


101
CCCAGACGCC TTCAGGCTTC CTTCTGTGCC ACCGTAACCA TAGCCGGGCG


 


151
CAACACGCGG TCGGACAGCG TATAACCCTT CTTCATCACG CCCACCACGG


 


201
TATTGGGTTC CTGTTCGCTT GCCACCGCCT GCATCGCCTG ATGGATATTC


 


251
GGATCGAGCT TATCGCCCGC TTTAGGATTG ATTTCCTTGA TTTGCGTAGC


 


301
ATCAAATGCT TTCTGCAACT CGTTCAAAGT CATCTGCACG CCCATTTTCA


 


351
GCGCATCGAA ATTGCCGCTC TGATCCAAAA GCGCCATTTC CAGATAATCC


 


401
TTGACCGGCA GCATTTCCAC GGCAAACTTC TGTCCGGCGA ACTTGTGCGT


 


451
ATCCGCAATT TCCTGCTGGT GGCGGCGGCG CAGGTTTTGC TCGTTTGCCA


 


501
AAGCGCGCAG CTGCTCGTCT TTCAACTGCG CTTCCAGCTC GGCAATCCGC


 


551
GCCTGCAAAT CCTCATAAGC CGGCTCTGCG GCAGCCTGTT CCTGCACACC


 


601
GTCCGCATTT CCTACTGTCT CGACGGTTTC CACCGCCTCC ACATTTTCAA


 


651
CCGCTTCTTC ACTGTTTTGC TGCTGTGTCT GTTCGCTCAT ATCGTATCCC


 


701
TTAAAACAAA TTGGAAATCA AAATCCAGTT ATTACCCGCG CAAGATAAGG


 


751
ACATTTTCAA GAAACTTCAA GCAAAGGCAG AGAATTTCAA ATTCATTTTC


 


801
AAATCCCCTA CCGAAAAAAT AA






This corresponds to the amino acid sequence <SEQ ID 940; ORF 244-1.a>:










a244-1.pep




1
MPSEARQAGS DGIAALLRSV YTQNALQEIN QIIPQTPSGF LLCHRNHSRA


 


51
QHAVGQRITL LHHAHHGIGF LFACHRLHRL MDIRIELIAR FRIDFLDLRS


 


101
IKCFLQLVQS HLHAHFQRIE IAALIQKRHF QIILDRQHFH GKLLSGELVR


 


151
IRNFLLVAAA QVLLVCQSAQ LLVFQLRFQL GNPRLQILIS RLCGSLFLHT


 


201
VRISYCLDGF HRLHIFNRFF TVLLLCLFAH IVSLKTNWKS KSSYYPRKIR


 


251
TFSRNFKQRQ RISNSFSNPL PKK*






m244-1/a244-1 96.8% identity in 274 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 941>:










g246.seq




1
atgtacgggc ggaacggtag tactcaagcg gccgttgcct tcgttttcga


 


51
ccagacacag cgtgcccgtt tcggcaacgg cgaagtttac gccgctcaag


 


101
ccgacatcgg cagtgctgta aatatcgcgc agggctttgc gggcgaatcc


 


151
ggtcagttgg tccacgtcgt ctgtaagcgg tgtgccgagg ttttggtgga


 


201
acagttcgct gacctgttct ttggttttat ggattgcggg catcacgata


 


251
tgggtcggtt tttcgcctgc catttggacg ataaactcgc ccaagtcgct


 


301
ttccaccgcc ttaatgcctt ttgcttcaag ataatggttc agctcgattt


 


351
cttcgctgac catggatttg cctttgacca tcagcttgcc gtttttggct


 


401
gtgatgatgt cgtggataat ttggcaggct tcggcagggg tttccgccca


 


451
gtgtactttc acgcccaact tagtcaggtt ttcttccaac tgctccagca


 


501
gcgcgggtaa






This corresponds to the amino acid sequence <SEQ ID 942; ORF 246.ng>:










g246.pep




1
MYGRNGSTQA AVAFVFDQTQ RARFGNGEVY AAQADIGSAV NIAQGFAGES


 


51
GQLVHVVCKR CAEVLVEQFA DLFFGFMDCG HHDMGRFFAC HLDDKLAQVA


 


101
FHRLNAFCFK IMVQLDFFAD HGFAFDHQLA VFGCDDVVDN LAGFGRGFRP


 


151
VYFHAQLSQV FFQLLQQRG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 943>:









m246.seq (partial)










1
ATGCACGGGC GGTACGGTGG TACTCAAGCG ACCGTTgCTT CGTTTTCCAC



 


51
CAGACACAGC GTACCTGTTT CAGCAACGGC AAAGTTTACG CCACTCAAAC


 


101
CGACATCGGC AGTGCTGTAA ATATCGCGCA GTGCTTTACG GGCGAAGCCG


 


151
GTCAGTTGGT CTACATCGTC TGTCAGCGGC GTACCGAGGT TTTGGTGGAA


 


201
CAGTTCGCTA ACCTGTTCTT TGGTTTTGTG GATAGCAGGC ATCACGATAT


 


251
GGGTCGGTTT TTCGCCTGCC ATTTGGACGA TGAACTCGCC CAAGTCGCTT


 


301
TCTACCGCTT TAATGCyTTT TGCTTCAAGA TAATGrTTCA GCTCGATTTC


 


351
CTCGCTGACC ATCGATTTGC CTTTGACCAT CAGCTTGCCG TTTTTGGCTG


 


401
TGATGATGTC GTGGATAATT TGGCAGGCTT CGGTCGGGGT TTCTGCCCG...






This corresponds to the amino acid sequence <SEQ ID 944; ORF 246>:









m246.pep (partial)










1
MHGRYGGTQA TVAFVFHQTQ RTCFSNGKVY ATQTDIGSAV NIAQCFTGEA



 


51
GQLVYIVCQR RTEVLVEQFA NLFFGFVDSR HHDMGRFFAC HLDDELAQVA


 


101
FYRFNAFCFK IMXQLDFLAD HRFAFDHQLA VFGCDDVVDN LAGFGRGFCP...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 246 shows 80.0% identity over a 150 aa overlap with a predicted ORF (ORF 246.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 945>:









a246.seq (partial)










1
ATGCACGGGC GGAACGGTGG TACTCAAGCG ACCGTTGCCT TCGTTTTCCA



 


51
CCAGACACAG CGTACCTGTT TCAGCAACGG CGAAGTTCAC GCCACTCAAA


 


101
CCGACATCGG CAGTGCTGTA AATATCGCGC AGTGCTTTAC GGGCGAAGCC


 


151
GGTCAGTTGG TCTACGTCGT CCGTTAACGG TGTGCCGAGG TTTTGGTGGA


 


201
ACAGTTCGCT AACCTGTTCT TTGGTTTTAT GGATTGCGGG CATCACGATA


 


251
TGGGTCGGTT TTTCACCTGC CATTTGGACG ATGAACTCGC CCAAGTCGCT


 


301
TTCCACCGCT TTAATGCCTT TTGCTTCAAG ATAATGGTTC AGCTCGATTT


 


351
CCTCGCTGAC CATCGATTTG CCTTTGACCA TCAGCTTGCC GTTTTTGGCT


 


401
GTGATGATGT CGTGGATGAT TTCGCAGGCT TCGGCCGGTG TTTCCGCCCA


 


451
GTGTACTTTT ACGCCCAACT TGGTCAGGTT TTCTTCCAGC TGCTCCAGCA


 


501
G






This corresponds to the amino acid sequence <SEQ ID 946; ORF 246.a>:









a246.pep (partial)










1
MHGRNGGTQA TVAFVFHQTQ RTCFSNGEVH ATQTDIGSAV NIAQCFTGEA



 


51
GQLVYVVR*R CAEVLVEQFA NLFFGFMDCG HHDMGRFFTC HLDDELAQVA


 


101
FHRFNAFCFK IMVQLDFLAD HRFAFDHQLA VFGCDDVVDD FAGFGRCFRP


 


151
VYFYAQLGQV FFQLLQQ






m246/a246 88.0% identity in 150 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 947>:










g247.seq




1
atgaaacgta aaatgctaaa cgtaccaaag ggcggttatg atggtatgaa


 


51
gggttttacc attgttgaat ttctggttgc gggcctgctc agtataattg


 


101
tcctgatagc ggtcgtatcg agttacttta catcccggaa attaaatgat


 


151
gtggcaaacg agcgtcttgc cattcaacag gatttgcgga atgcggcaac


 


201
attaattgtc cgcgatgcaa gaatggcggg gagcttcggt tgtttcaata


 


251
tgtccgagca tactaaagac gatattgttg attcaagtaa tcaaactcaa


 


301
tctaaccttg caaaacccgg tgccaaacaa gaaaatcccc ttttttcctt


 


351
aaaaaggagc ggcatggata aacaactgat tcccgttgct gaatccatag


 


401
atattaaata tccgggtttt atccagcgcc ttaacgcatt ggttttccaa


 


451
tacggtatcg atgatcttga tgcgagtgct gagactgttg tagtcagcag


 


501
ctgttccaaa atagcaaaac cgggtaagaa aatatctacc ttgcaagaag


 


551
caaagagtgc attacagatt actaatgatg ataaacaaaa tggaaatatc


 


601
acccgtcaga aacatgtggt caatgcctat gcggtcggca ggtttggcaa


 


651
taatgaggaa agtttgttcc gcttccaatt ggatgataag ggcaagtggg


 


701
gtaatcctca gttgctcgtg aaaaaggtta aacgtatgga tgtgcggtat


 


751
atttatgttt ccggttgtcc tgaagatgaa gatgccggca aagaggaaaa


 


801
attcagatat acgaataaat tcgacaaatc caaaaatgct gttacgcctg


 


851
ccggggtgga ggttttattg gatagcggcc ttaatgccaa gattgccgct


 


901
tcttcagaca atagtattta tgcttaccgt atcaatgcga caatacgcgg


 


951
gggaaatgta tgcgcaaaca gaacactttg a






This corresponds to the amino acid sequence <SEQ ID 948; ORF 247.ng>:










g247.pep




1
MKRKMLNVPK GGYDGMKGFT IVEFLVAGLL SIIVLIAVVS SYFTSRKLND


 


51
VANERLAIQQ DLRNAATLIV RDARMAGSFG CFNMSEHTKD DIVDSSNQTQ


 


101
SNLAKPGAKQ ENPLFSLKRS GMDKQLIPVA ESIDIKYPGF IQRLNALVFQ


 


151
YGIDDLDASA ETVVVSSCSK IAKPGKKIST LQEAKSALQI TNDDKQNGNI


 


201
TRQKHVVNAY AVGRFGNNEE SLFRFQLDDK GKWGNPQLLV KKVKRMDVRY


 


251
IYVSGCPEDE DAGKEEKFRY TNKFDKSKNA VTPAGVEVLL DSGLNAKIAA


 


301
SSDNSIYAYR INATIRGGNV CANRTL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 949>:









m247.seq (partial)










1
ATsAGACGTA AAATGCTAAA CGTwsyArAA GGCAGTTATG ATGGTATGAA



 


51
AGGTTTTACC ATTATTGAAT TTTTGGTTGC GGGCCTGCTC AGTATGATTG


 


101
TCCTGATGGC GGTCGGATCG AGTTACTTCA CATCCCGGAA ATTAAATGAT


 


151
GCGGCAAACG AGCGTCTTGC CGCGCAACAG GATTTGCGGA ATGCGGCAAC


 


201
ATTGATTGTC CGCGATGCGA GAATGGCAGG CGGCTTCGGT TGTTTCAATA


 


251
TGTCCGAGCA TCCTGCAACT GATGTTATTC CCGATACGAC GCAACAAAAT


 


301
TCTCCTTTTT CCTTAAAAAG GAACGGTATA GATAAACTTA TTCCCATAGC


 


351
GGAATCTTCA AATATCAATT ATCAGAATTT TTTCCAGGTT GGTAGCGCAT


 


401
TGATTTTTCA ATACGGAATC GATGATGTTA ATGCAAGCAC CGCGACTACC


 


451
GTCGTCAGCA GCTGTGCCGC AATATCGAAA CCGGGCAAGC AAATCCCTAC


 


501
TTTAGAAGAT GCAAAAAAAG AATTGAAGAT TCCGGATCAG GATAAGGAGC


 


551
AAAATGGCAA TATAGCGCGT CAAAGGCATG TGGTCAATGC CTATGCGGTC


 


601
GGCAGGATTG CCGATGAGGA AAGTTTGTTC CGCTTCCAAT TGGATGATAA


 


651
GGGCAAGTGG GGTAATCCTC AGTTGC...






This corresponds to the amino acid sequence <SEQ ID 950; ORF 247>:









m247.pep (partial)










1
XRRKMLNVXX GSYDGMKGFT IIEFLVAGLL SMIVLMAVGS SYFTSRKLND



 


51
AANERLAAQQ DLRNAATLIV RDARMAGGFG CFNMSEHPAT DVIPDTTQQN


 


101
SPFSLKRNGI DKLIPIAESS NINYQNFFQV GSALIFQYGI DDVNASTATT


 


151
VVSSCAAISK PGKQIPTLED AKKELKIPDQ DKEQNGNIAR QRHVVNAYAV


 


201
GRIADEESLF RFQLDDKGKW GNPQL....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 247 shows 69.3% identity over a 238 aa overlap with a predicted ORF (ORF 247.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 951>:










a247.seq




1
ATGAGACGTA AAATGCTAAA CGTACCAAAA GGCAATTATG ATGGTATGAA


 


51
GGGTTTTACC ATTATTGAAT TTTTGGTTGC GGGCATGCTC AGTATGATTG


 


101
TCCTGATGGC GGTCGGATCG AGTTACTTCA CATCCCGGAA ATTAAATGAT


 


151
GCGGCAAACG AGCGTCTTTC CGCGCAACAG GATTTGCGGA ATGCGGCAAC


 


201
ATTGATTGTC CGCGATGCAA GAATGGCAGG GGGCTTCGGT TGTTTCAATA


 


251
TGTCCGAGCA TACTAAAAAT GATATTATTG TTGATCCAAG TAAGCAAACT


 


301
CAACATGTCC CTGTAAAACC CGGTGCCAAA CAAGAAAATC CCCTTTTTTC


 


351
TTTAGAGTGG GCTAATACTA ATAATACTAA TAATAATACA GCTAAATTGA


 


401
TTCCTATTGC TGAATCCACA GATATTAAAT ATCCGGGTTT TGCCCAGGCT


 


451
CGTCCGGCAT TGATTTTCCA ATACGGCATC GATGATCTTG ATGCGAGTGC


 


501
TGAGACTGTT GTAGTCAGCA GCTGTTCCAA AATAGCAAAA CCGGGTAAGA


 


551
AAATATCTAC CTTGCAAGAA GCAAAGAGTG CATTACAGAT TACTAATGAT


 


601
GATAAACAAA ATGGAAATAT CACCCGTCAA AGGCATGTGG TCAATGCCTA


 


651
TGCGGTCGGC AGGATTGCCG GTGAGGAAGG TTTGTTCCGC TTCCAATTGG


 


701
ATGATAAGGG CAAGTGGGGT AATCCTCAGT TGCTCGTGAA AAAGATTAGA


 


751
CATATGAAAG TGCGGTATAT CTATGTTTCC GACTGTCCTG AAGATGACGA


 


801
TGCCGGCAAA GAGGAAAAAT TCAAATATAC GGGTACATTC GACAGCTCCA


 


851
CAAATGCTGT TACGCCCGCC GGGGTGGAGG TTTTATTGAG TANCGGTACT


 


901
GATACCAAGA TTGCCGCTTC TTCAGACAAT CATATTTATG CTTACCGTAT


 


951
CGATGCGACA ATACGCGGGG GAAATGTATG CGCAAACAGA ACACTTTGA






This corresponds to the amino acid sequence <SEQ ID 952; ORF 247.a>:










a247.pep




1
MRRKMLNVPK GNYDGMKGFT IIEFLVAGML SMIVLMAVGS SYFTSRKLND


 


51
AANERLSAQQ DLRNAATLIV RDARMAGGFG CFNMSEHTKN DIIVDPSKQT


 


101
QHVPVKPGAK QENPLFSLEW ANTNNTNNNT AKLIPIAEST DIKYPGFAQA


 


151
RPALIFQYGI DDLDASAETV VVSSCSKIAK PGKKISTLQE AKSALQITND


 


201
DKQNGNITRQ RHVVNAYAVG RIAGEEGLFR FQLDDKGKWG NPQLLVKKIR


 


251
HMKVRYIYVS DCPEDDDAGK EEKFKYTGTF DSSTNAVTPA GVEVLLSXGT


 


301
DTKIAASSDN HIYAYRIDAT IRGGNVCANR TL*






m247/a247 70.9% identity in 244 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 953>:









g247-1.seq (partial) ..










1
CCCGGTGCCA AACAAGAAAA TCCCCTTTTT TCCTTAAAAA GGAGCGGCAT



 


51
GGATAAACAA CTGATTCCCG TTGCTGAATC CATAGATATT AAATATCCGG


 


101
GTTTTATCCA GCGCCTTAAC GCATTGGTTT TCCAATACGG TATCGATGAT


 


151
CTTGATGCGA GTGCTGAGAC TGTTGTAGTC AGCAGCTGTT CCAAAATAGC


 


201
AAAACCGGGT AAGAAAATAT CTACCTTGCA AGAAGCAAAG AGTGCATTAC


 


251
AGATTACTAA TGATGATAAA CAAAATGGAA ATATCACCCG TCAGAAACAT


 


301
GTGGTCAATG CCTATGCGGT CGGCAGGTTT GGCAATAATG AGGAAAGTTT


 


351
GTTCCGCTTC CAATTGGATG ATAAGGGCAA GTGGGGTAAT CCTCAGTTGC


 


401
TCGTGAAAAA GGTTAAACGT ATGGATGTGC GGTATATTTA TGTTTCCGGT


 


451
TGTCCTGAAG ATGAAGATGC CGGCAAAGAG GAAAAATTCA GATATACGAA


 


501
TAAATTCGAC AAATCCAAAA ATGCTGTTAC GCCTGCCGGG GTGGAGGTTT


 


551
TATTGGATAG CGGCCTTAAT GCCAAGATTG CCGCTTCTTC AGACAATAGT


 


601
ATTTATGCTT ACCGTATCAA TGCGACAATA CGCGGGGGAA ATGTATGCGC


 


651
AAACAGAACA CTTTGA






This corresponds to the amino acid sequence <SEQ ID 954; ORF 247-1.ng>:









g247-1.pep (partial) ..










1
PGAKQENPLF SLKRSGMDKQ LIPVAESIDI KYPGFIQRLN ALVFQYGIDD



 


51
LDASAETVVV SSCSKIAKPG KKISTLQEAK SALQITNDDK QNGNITRQKH


 


101
VVNAYAVGRF GNNEESLFRF QLDDKGKWGN PQLLVKKVKR MDVRYIYVSG


 


151
CPEDEDAGKE EKFRYTNKFD KSKNAVTPAG VEVLLDSGLN AKIAASSDNS


 


201
IYAYRINATI RGGNVCANRT L*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 955>:










m247-1.seq




1
ATGAGACGTA AAATGCTAAA CGTACCAAAA GGCAGTTATG ATGGTATGAA


 


51
AGGTTTTACC ATTATTGAAT TTTTGGTTGC GGGCCTGCTC AGTATGATTG


 


101
TCCTGATGGC GGTCGGATCG AGTTACTTCA CATCCCGGAA ATTAAATGAT


 


151
GCGGCAAACG AGCGTCTTGC CGCGCAACAG GATTTGCGGA ATGCGGCAAC


 


201
ATTGATTGTC CGCGATGCGA GAATGGCAGG CGGCTTCGGT TGTTTCAATA


 


251
TGTCCGAGCA TCCTGCAACT GATGTTATTC CCGATACGAC GCAACAAAAT


 


301
TCTCCTTTTT CCTTAAAAAG GAACGGTATA GATAAACTTA TTCCCATAGC


 


351
GGAATCTTCA AATATCAATT ATCAGAATTT TTTCCAGGTT GGTAGCGCAT


 


401
TGATTTTTCA ATACGGAATC GATGATGTTA ATGCAAGCAC CGCGACTACC


 


451
GTCGTCAGCA GCTGTGCCGC AATATCGAAA CCGGGCAAGC AAATCCCTAC


 


501
TTTAGAAGAT GCAAAAAAAG AATTGAAGAT TCCGGATCAG GATAAGGAGC


 


551
AAAATGGCAA TATAGCGCGT CAAAGGCATG TGGTCAATGC CTATGCGGTC


 


601
GGCAGGATTG CCGATGAGGA AGGTTTGTTC CGCTTCCAAT TGGATGATAA


 


651
GGGCAAGTGG GGTAATCCTC AGTTGCTCGT GAAAAAGGTT AGACATATGA


 


701
AAGTGCGGTA TATCTATGTT TCCGGCTGTC CTGAAGATGA CGATGCCGGC


 


751
AAAGAGGAAA CATTCAAATA TACGGATAAA TTCGACAGCG CCCAAAATGC


 


801
TGTTACGCCC GCCGGGGTGG AGGTTTTATT GAGTAGCGGT ACTGATACCA


 


851
AGATTGCCGC TTCTTCAGAC AATCATATTT ATGCTTACCG TATCGATGCG


 


901
ACAATACGCG GGGGAAATGT ATGCGCAAAC AGAACACTTT GA






This corresponds to the amino acid sequence <SEQ ID 956; ORF 247-1>:










m247-1.pep




1
MRRKMLNVPK GSYDGMKGFT IIEFLVAGLL SMIVLMAVGS SYFTSRKLND


 


51
AANERLAAQQ DLRNAATLIV RDARMAGGFG CFNMSEHPAT DVIPDTTQQN


 


101
SPFSLKRNGI DKLIPIAESS NINYQNFFQV GSALIFQYGI DDVNASTATT


 


151
VVSSCAAISK PGKQIPTLED AKKELKIPDQ DKEQNGNIAR QRHVVNAYAV


 


201
GRIADEEGLF RFQLDDKGKW GNPQLLVKKV RHMKVRYIYV SGCPEDDDAG


 


251
KEETFKYTDK FDSAQNAVTP AGVEVLLSSG TDTKIAASSD NHIYAYRIDA


 


301
TIRGGNVCAN RTL*






m247-1/g247-1 72.1% identity in 222 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 957>:









a247-1.seq (partial)










1
AATAATACAG CTAAATTGAT TCCTATTGCT GAATCCACAG ATATTAAATA



 


51
TCCGGGTTTT GCCCAGGCTC GTCCGGCATT GATTTTCCAA TACGGCATCG


 


101
ATGATCTTGA TGCGAGTGCT GAGACTGTTG TAGTCAGCAG CTGTTCCAAA


 


151
ATAGCAAAAC CGGGTAAGAA AATATCTACC TTGCAAGAAG CAAAGAGTGC


 


201
ATTACAGATT ACTAATGATG ATAAACAAAA TGGAAATATC ACCCGTCAAA


 


251
GGCATGTGGT CAATGCCTAT GCGGTCGGCA GGATTGCCGG TGAGGAAGGT


 


301
TTGTTCCGCT TCCAATTGGA TGATAAGGGC AAGTGGGGTA ATCCTCAGTT


 


351
GCTCGTGAAA AAGATTAGAC ATATGAAAGT GCGGTATATC TATGTTTCCG


 


401
ACTGTCCTGA AGATGACGAT GCCGGCAAAG AGGAAAAATT CAAATATACG


 


451
GGTACATTCG ACAGCTCCAC AAATGCTGTT ACGCCCGCCG GGGTGGAGGT


 


501
TTTATTGAGT AGCGGTACTG ATACCAAGAT TGCCGCTTCT TCAGACAATC


 


551
ATATTTATGC TTACCGTATC GATGCGACAA TACGCGGGGG AAATGTATGC


 


601
GCAAACAGAA CACTTTGA






This corresponds to the amino acid sequence <SEQ ID 958; ORF 247-1.a>:









a247-1.pep (partial) ..










1
NNTAKLIPIA ESTDIKYPGF AQARPALIFQ YGIDDLDASA ETVVVSSCSK



 


51
IAKPGKKIST LQEAKSALQI TNDDKQNGNI TRQRHVVNAY AVGRIAGEEG


 


101
LFRFQLDDKG KWGNPQLLVK KIRHMKVRYI YVSDCPEDDD AGKEEKFKYT


 


151
GTFDSSTNAV TPAGVEVLLS SGTDTKIAAS SDNHIYAYRI DATIRGGNVC


 


201
ANRTL*






m247-1/a247-1 80.6% identity in 206 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 959>:










g248.seq




1
atgcgcaaac agaacacttt gacaggaatc ccgacttctg acggacagag


 


51
ggggtccgca ctgtttatcg tgctgatggt gatgatagtc gtggcctttt


 


101
tggttgtaac tgccgcccag tcctacaata ccgaacagag gatcagtgcc


 


151
aacgaatcag acaggaaatt ggctttgtct ttagccgagg cggctttgcg


 


201
ggagggcgaa tttcaggttt tggatttgga atatgctgcg gacagtaagg


 


251
ttacgtttag cgaaaactgt gaaaaaggtc tgtgtaccgc agtgaatgtg


 


301
cggacaaata ataatggtag tgaagaggct tttggcaata tcgtggtgca


 


351
aggcaagccc gccgttgagg cggtgaaacg ttcttgccct gcaaagtctg


 


401
gcaaaaattc taccgacctg tgcattgaca ataaagggat ggaatataat


 


451
aaaggcgcgg caggcgtcag caaaatgccg cgctatatta tcgaatattt


 


501
aggcgtgaag aacggacaaa atgtttatcg ggttactgcc aaggcttggg


 


551
gtaagaatgc caataccgtg gtcgtccttc aatcttatgt aggcaataat


 


601
gatgagcaat aa






This corresponds to the amino acid sequence <SEQ ID 960; ORF 248.ng>:










g248.pep




1
MRKQNTLTGI PTSDGQRGSA LFIVLMVMIV VAFLVVTAAQ SYNTEQRISA


 


51
NESDRKLALS LAEAALREGE FQVLDLEYAA DSKVTFSENC EKGLCTAVNV


 


101
RTNNNGSEEA FGNIVVQGKP AVEAVKRSCP AKSGKNSTDL CIDNKGMEYN


 


151
KGAAGVSKMP RYIIEYLGVK NGQNVYRVTA KAWGKNANTV VVLQSYVGNN


 


201
DEQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 961>:









m248.seq (partial)










1
..GGGTTTGCAC TGTTAATCGT GCTGATGGTG ATrATCGTCG TGGCT.TywT



 


51
  gGwTGTAACT GCCGCGCAGT CTTACAATAC cGAGCAGCGk ATCAGTkCCA


 


101
  ACGAATCAGA CAGGAAATTG GCTwTGTCTT TGGCCGAGkC GkCTwTGCGG


 


151
  GAAGGCGAAC TTCAGGTTTT GGATTTGGAA TATGATACGG ACAGTAAGGT


 


201
  TACATTTAGC GAAAACTGTG GAAAAGGTCT GTsTGCCGCA GTGAATGTGC


 


251
  GGACAAATAA TGATAATGAA GAGGCTTTTG ACAATATCGT GGTGCAAGGC


 


301
  AAGCCCACCG TTGAGGCGGT GAAGCGTTCT TGCCCTGCAA ATTCTACCGA


 


351
  CCTGTGCATT GACAAGAAAG GGwTGGAATA TAAGAAAGGC ACGAGAAGCG


 


401
  TCAc.AAAAT GCCACGTTAT ATTATCGAAT ATTTGGGCGT GwAGAACGGA


 


451
  GAAAATGTTT ATCGGGTTAC TGCCAAGGCT TGGGGtAAGA ATGCCAATAC


 


501
  CGTGGTCGTC CTTCAATCTT ATGTAAGCAA TAATGATGAG TAA






This corresponds to the amino acid sequence <SEQ ID 962; ORF 248>:









m248.pep (partial)










1
..GFALLIVLMV XIVVAFXXVT AAQSYNTEQR ISXNESDRKL AXSLAEXXXR



 


51
  EGELQVLDLE YDTDSKVTFS ENCGKGLXAA VNVRTNNDNE EAFDNIVVQG


 


101
  KPTVEAVKRS CPANSTDLCI DKKGXEYKKG TRSVTKMPRY IIEYLGVXNG


 


151
  ENVYRVTAKA WGKNANTVVV LQSYVSNNDE *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 248 shows 81.1% identity over a 185 aa overlap with a predicted ORF (ORF 248.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 963>:










a248.seq




1
ATGCGCAAAC AGAACACTTT GACGGGAATC CCGACTTCTG ACGGACAGAG


 


51
GGGGTTTGCA CTGTTTATCG TGCTGATGGT GATGATCGTC GTGGCTTTTT


 


101
TGGTTGTAAC TGCCGCGCAG TCTTACAATA CCGAGCAGCG GATCAGTGCC


 


151
AACGAATCAG ACAGGAAATT GGCTTTGTCT TTGGCCGAGG CGGCTTTGCG


 


201
GGAAGGCGAA CTTCAGGTTT TGGATTTGGA ATATGATACG GACAGTAAGG


 


251
TTACATTTAG CGAAAACTGT GGAAAAGGTC TGTGTACCGC AGTGAATGTG


 


301
CGGACAAATA ATGATAATGA AGAGGCTTTT GACAATATCG TGGTGCAAGG


 


351
CAAGCCCACC GTTGAGGCGG TGAAGCGTTC TTGCACTGCA AAATCTACAG


 


401
GCCTGTGCAT TGACAATAAA GGGATGGAAT ATAAGAAAGG CACGCAAAGC


 


451
GTCAGCAAAA TGCCACGTTA TATTATCGAA TATTTGGGCG TGAAGAACGG


 


501
AGAAAATGTT TATCGGGTTA CTGCCAAGGC TTGGGGTAAG AATGCCAATA


 


551
CCGTGGTCGT CCTTCAATCT TATGTAAGCA ATAATGATGA GTAA






This corresponds to the amino acid sequence <SEQ ID 964; ORF 248.a>:










a248.pep




1
MRKQNTLTGI PTSDGQRGFA LFIVLMVMIV VAFLVVTAAQ SYNTEQRISA


 


51
NESDRKLALS LAEAALREGE LQVLDLEYDT DSKVTFSENC GKGLCTAVNV


 


101
RTNNDNEEAF DNIVVQGKPT VEAVKRSCTA KSTGLCIDNK GMEYKKGTQS


 


151
VSKMPRYIIE YLGVKNGENV YRVTAKAWGK NANTVVVLQS YVSNNDE*






m248/a248 89.4% identity in 180 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 965>:










m248-1.seq




1
ATGCGCAAAC AGAACACTTT GACGGGAATC CCGACTTCTG ACGGACAGAG


 


51
GGGGTTTGCA CTGTTTATCG TGCTGATGGT GATGATCGTC GTGGCTTTTT


 


101
TGGTTGTAAC TGCCGCGCAG TCTTACAATA CCGAGCAGCG GATCAGTGCC


 


151
AACGAATCAG ACAGGAAATT GGCTTTGTCT TTGGCCGAGG CGGCTTTGCG


 


201
GGAAGGCGAA CTTCAGGTTT TGGATTTGGA ATATGATACG GACAGTAAGG


 


251
TTACATTTAG CGAAAACTGT GGAAAAGGTC TGTGTGCCGC AGTGAATGTG


 


301
CGGACAAATA ATGATAATGA AGAGGCTTTT GACAATATCG TGGTGCAAGG


 


351
CAAGCCCACC GTTGAGGCGG TGAAGCGTTC TTGCCCTGCA AATTCTACCG


 


401
ACCTGTGCAT TGACAAGAAA GGGATGGAAT ATAAGAAAGG CACGAGAAGC


 


451
GTCAGCAAAA TGCCACGTTA TATTATCGAA TATTTGGGCG TGAAGAACGG


 


501
AGAAAATGTT TATCGGGTTA CTGCCAAGGC TTGGGGTAAG AATGCCAATA


 


551
CCGTGGTCGT CCTTCAATCT TATGTAAGCA ATAATGATGA GTAA






This corresponds to the amino acid sequence <SEQ ID 966; ORF 248-1>:










m248-1.pep




1
MRKQNTLTGI PTSDGQRGFA LFIVLMVMIV VAFLVVTAAQ SYNTEQRISA


 


51
NESDRKLALS LAEAALREGE LQVLDLEYDT DSKVTFSENC GKGLCAAVNV


 


101
RTNNDNEEAF DNIVVQGKPT VEAVKRSCPA NSTDLCIDKK GMEYKKGTRS


 


151
VSKMPRYIIE YLGVKNGENV YRVTAKAWGK NANTVVVLQS YVSNNDE*






m248-1/g248 89.1% identity in 202 aa overlap





m248-1/a248 97.0% identity in 197 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 967>:










g249.seq




1
atgaagaata atgattgctt gcgcctgaaa aatccccagt ccggtatggc


 


51
gttgatagaa gtcttggtcg ctatgctcgt tctgaccatc ggtattttgg


 


101
cattgctgtc cgtacagttg cggacagtcg cttccgtcag ggaggcggaa


 


151
acgcaaacca tcgtcagcca aatcacgcaa aacctgatgg aaggaatgtt


 


201
gatgaatccg accattgatt tggacagcaa caagaaaaac tatagtcttt


 


251
acatgggaaa acagacacta tcagctgtgg atggtgagtt tatgcttgat


 


301
gccgagaaaa gtaaggcgca gttggcagag gaacaattga agagatttag


 


351
tcatgagctg aaaaatgcct tgccggatgc ggtagctatt cattacgccg


 


401
tctgcaagga ttcgtcgggt gacgcgccga cattgtccga cagcggtgct


 


451
ttttcttcaa attgcgacaa taaggcaaac ggggatactt tgattaaagt


 


501
attgtgggta aatgattcgg caggggattc ggatatttcc cgtacgaatc


 


551
ttgaagtgag cggcgacaat atcgtatata cctatcaggc aagggtcgga


 


601
ggtcgtgaat ga






This corresponds to the amino acid sequence <SEQ ID 968; ORF 249.ng>:










g249.pep




1
MKNNDCLRLK NPQSGMALIE VLVAMLVLTI GILALLSVQL RTVASVREAE


 


51
TQTIVSQITQ NLMEGMLMNP TIDLDSNKKN YSLYMGKQTL SAVDGEFMLD


 


101
AEKSKAQLAE EQLKRFSHEL KNALPDAVAI HYAVCKDSSG DAPTLSDSGA


 


151
FSSNCDNKAN GDTLIKVLWV NDSAGDSDIS RTNLEVSGDN IVYTYQARVG


 


201
GRE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 969>:










m249.seq




1
ATGAAGAATA ATGATTGCTT CCGCCTGAAA GATTCCCAGT CCGGTATGGC


 


51
GCTGATAGAA GTCTTGGTTG CTATGCTCGT TCTGACCATC GGTATTTTGG


 


101
CACTATTGTC TGTACAGTTG CGGACAGTCN NNNNNNNNNN NNNNNNNNNN


 


151
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNTTGATGG AGGGAATGTT


 


201
GATGAATCCG ACCATTGATT CGGACAGCAA CAAGAAAAAC TATAATCTTT


 


251
ACATGGGAAA CCATACACTA TCAGCTGTGG ATGGCGATTT TGCGATTGAT


 


301
GCCATGAAAA CTAAGGGGCA ATTGGCAGAG GCACAATTGA AGAGATTTAG


 


351
TTATGAGCTG AAAAATGCCT TGCCGGATGC GGCAGCCATC CATTACGCCG


 


401
TCTGCAAGGA TTCGTCGGGT AACGCGCCGA CATTGTCCGG CAATGCTTTT


 


451
TCTTCAAATT GCGACAATAA GGCAAACGGG GATACTTTAA TTAAAGTATT


 


501
GTGGGTAAAT GATTCGGCAG GGGATTCGGA TATTTCCCGT ACGAATCTTG


 


551
AGGTGAGCGG CGACAATATC GTATATACTT ATCAGGCAAG GGTCGGAGGT


 


601
CGGGAATGA






This corresponds to the amino acid sequence <SEQ ID 970; ORF 249>:










m249.pep




1
MKNNDCFRLK DSQSGMALIE VLVAMLVLTI GILALLSVQL RTVXXXXXXX


 


51
XXXXXXXXXX XLMEGMLMNP TIDSDSNKKN YNLYMGNHTL SAVDGDFAID


 


101
AMKTKGQLAE AQLKRFSYEL KNALPDAAAI HYAVCKDSSG NAPTLSGNAF


 


151
SSNCDNKANG DTLIKVLWVN DSAGDSDISR TNLEVSGDNI VYTYQARVGG


 


201
RE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 249 shows 81.3% identity over a 203 aa overlap with a predicted ORF (ORF 249.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 971>:










a249.seq




1
ATGAAGAATA ATGATTGCTT CCGCCTGAAA AACCCCCAGT CCGGTATGGC


 


51
GCTGATAGAA GTCTTGGTCG CTATGCTCGT TCTGACCATC GGTATTTTGG


 


101
CACTATTGTC TGTTCAGTTG CGGACAGTCG CTTCCGTCAG GGAGGCAGAG


 


151
ACGCAAACCA TCGTCAGTCA AATCACGCAA AACCTGATGG AAGGAATGTT


 


201
GATGAATCCG ACCATTGATT CGGACAGCAA CAAGAAAAAC TATAATCTTT


 


251
ACATGGGAAA CCATCATGCA CTATCAGTTG TGGATGGCGA TTTTCAGGTT


 


301
GATGCCATAA AAACTAAGAC GCAGTTGGCA GAGGCACAAT TGAAGAGATT


 


351
TAGTTATGAG CTGAAAAATG CCTTGCCGGA TGCGGCAGCC ATCCATTACG


 


401
CCGTCTGCAA GGATTCGTCG GGTGTTGCGC CGACATTGTC CGCCGGCAGT


 


451
ACTTTTTCTT CAAATTGCGA TGGTAGTGCA AATGGGGATA CTTTGATTAA


 


501
AGTATTGTGG GTAAATGATT CGGCAGGGGA TTCGGATATC GCCCGTACGA


 


551
ATCTTGAGAC GAACGGCAAC AATATCGTAT ATACCTATCA GGCAAGGGTC


 


601
GGAGGTCGGG AATGA






This corresponds to the amino acid sequence <SEQ ID 972; ORF 249.a>:










a249.pep




1
MKNNDCFRLK NPQSGMALIE VLVAMLVLTI GILALLSVQL RTVASVREAE


 


51
TQTIVSQITQ NLMEGMLMNP TIDSDSNKKN YNLYMGNHHA LSVVDGDFQV


 


101
DAIKTKTQLA EAQLKRFSYE LKNALPDAAA IHYAVCKDSS GVAPTLSAGS


 


151
TFSSNCDGSA NGDTLIKVLW VNDSAGDSDI ARTNLETNGN NIVYTYQARV


 


201
GGRE*






m249/a249 81.9% identity in 204 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 973>:










m249-1.seq




1
ATGAAGAATA ATGATTGCTT CCGCCTGAAA GATTCCCAGT CCGGTATGGC


 


51
GCTGATAGAA GTCTTGGTTG CTATGCTCGT TCTGACCATC GGTATTTTGG


 


101
CACTATTGTC TGTACAGTTG CGGACAGTCG CTTCCGTCAG GGAGGCGGAG


 


151
ACACAAACCA TCGTCAGCCA AATCACGCAA AACCTGATGG AGGGAATGTT


 


201
GATGAATCCG ACCATTGATT CGGACAGCAA CAAGAAAAAC TATAATCTTT


 


251
ACATGGGAAA CCATACACTA TCAGCTGTGG ATGGCGATTT TGCGATTGAT


 


301
GCCATGAAAA CTAAGGGGCA ATTGGCAGAG GCACAATTGA AGAGATTTAG


 


351
TTATGAGCTG AAAAATGCCT TGCCGGATGC GGCAGCCATC CATTACGCCG


 


401
TCTGCAAGGA TTCGTCGGGT AACGCGCCGA CATTGTCCGG CAATGCTTTT


 


451
TCTTCAAATT GCGACAATAA GGCAAACGGG GATACTTTAA TTAAAGTATT


 


501
GTGGGTAAAT GATTCGGCAG GGGATTCGGA TATTTCCCGT ACGAATCTTG


 


551
AGGTGAGCGG CGACAATATC GTATATACTT ATCAGGCAAG GGTCGGAGGT


 


601
CGGGAATGA






This corresponds to the amino acid sequence <SEQ ID 974; ORF 249-1>:










m249-1.pep




1
MKNNDCFRLK DSQSGMALIE VLVAMLVLTI GILALLSVQL RTVASVREAE


 


51
TQTIVSQITQ NLMEGMLMNP TIDSDSNKKN YNLYMGNHTL SAVDGDFAID


 


101
AMKTKGQLAE AQLKRFSYEL KNALPDAAAI HYAVCKDSSG NAPTLSGNAF


 


151
SSNCDNKANG DTLIKVLWVN DSAGDSDISR TNLEVSGDNI VYTYQARVGG


 


201
RE*






m249-1/g249 90.1% identity in 203 aa overlap





a249/L36117









gi|643582 (L36117) prepilin leader sequence requires cleavage



to be active [Pseudomonas aeruginosa]


>gi|1161222 (L48934) involved in type 4 fimbrial biogenesis; contains


pre-pilin like leader sequence [Pseudomonas aeruginosa]


>gip|1246299 (L76605) reference L36117, L48934 [Pseudomonas aeruginosa]


Length = 185


Score = 50.4 bits (118), Expect = 9e−06


Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 26/183 (14%)











Query:
13
QSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTI
72





QSG ++IEVLVA+L+++IG+L ++++Q +T+    ++  +   + +  NL+E M  +P


Sbjct:
12
QSGFSMIEVLVALLLISIGVLGMIAMQGKTIQYTADSVERNKAAMLGSNLLESMRASPKA
71


 


Query:
73
DSDSNKKNYNLYMGNHHALSVVDGDFQVDAIKTKTQLAEA---QLKRFSYELKNALPDAA
129




  D   +     M          G     A  + T L +A   +L  ++ ++KN LP A


Sbjct:
72
LYDVKDQMATQSDFFKAKGSAFPTAPSSCTPLPDAIKDRLGCWAEQVKNELPGAG
126


 


Query:
130
AI---HYAVCKDSSGVAPTLSAGSTFSSNCDGSANGDTL-IKVLWVNDSAGDSDIARTNL
185




 +    Y +C+ S          +CDG   G  L I++ W        + A ++


Sbjct:
127
DLLKSDYYICRSSKPGDCDG--KGSMLEIRLAWRGKQGACVNAADSSA
172


 


Query:
186
ETN 188




+T+


Sbjct:
173
DTS 175






m249-1/a249 90.7% identity in 204 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 975>:










g250.seq




1
atgacgcaca cagcctctcc acgtgatgaa ttcatacgcg gcataaaaga


 


51
aagttcgccc atgctgattg ggcttttgcc ttgggcattg atactcggta


 


101
tgcagggcgg gcaaaaaggt atgggccggc tggaaatgct gctgatgacg


 


151
gggatgaact ttgccggcgg ctccgaattt gccacggtca acctgtgggc


 


201
ggaacctctg ccgatactgc ttatcgccac cataaccttt atgattaatt


 


251
cgcggcatat cctgatgggg ggcggcgctt gccacgcaca tgaaagaaat


 


301
accgctgaaa aaagccgcgc ccgcgctgtt ttttatgtgt ga






This corresponds to the amino acid sequence <SEQ ID 976; ORF 250.ng>:










g250.pep




1
MTHTASPRDE FIRGIKESSP MLIGLLPWAL ILGMQGGQKG MGRLEMLLMT


 


51
GMNFAGGSEF ATVNLWAEPL PILLIATITF MINSRHILMG GGACHAHERN


 


101
TAEKSRARAV FYV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 977>:










m250.seq




1
ATGCACACCT TCCCCGCATA ACGAATTTAT ACGCGGCATC AAAGAAAGTT


 


51
CGCCTATGCT GATTGGGCTG CTGCCTTGGG CATTAATACT CGGTATGCAG


 


101
GGCGGACAAA AAGGCATGAG CTGGCTGGAA ATGTTGTTGA TGACCAGTAT


 


151
GAACTTCGCC GGCGGCTCCG AGTTTGCCAC GGTCAACCTG TGGGCsGAAC


 


201
CTCTGCCGAT ACTGCTTATC GCCACCGTAA CCTTTATGAT TAATTCTCGG


 


251
CATATCCTGA T.GGGGGCGG CGCTTGCCCC GCACCTGAAA GGAaTACCGC


 


301
TGAAAAAAGC CGTGCCCGCA CTGTTTTTTA TGTGTGA






This corresponds to the amino acid sequence <SEQ ID 978; ORF 250>:










m250.pep




1
MHTPSPHNEF IRGIKESSPM LIGLLPWALI LGMQGGQKGM SWLEMLLMTS


 


51
MNFAGGSEFA TVNLWAEPLP ILLIATVTFM INSRHILMGG GACPAPERNT


 


101
AEKSRARTVF YV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 250 shows 91.0% identity over a 111 aa overlap with a predicted ORF (ORF 250.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 979>:










a250.seq




1
ATGACACACA TAAGCTCGCC CCGTAACGAA TTTATACGCG GCATCAAAGA


 


51
AAGTTCGCCC ATGCTGATCG GGCTTTTGCC TTGGGCATTA ATACTCGGTA


 


101
TGCAGGGTGG ACAAAAAGGC ATGAGCTGGC TGGAAATGTT GTTGATGACC


 


151
GGTATGAACT TCGCCGGCGG CTCCGAGTTT GCCACGGTCA ACCTGTGGGC


 


201
GGAACCTCTG CCGATACTGC TTATCGCCAC CGTAACCTTT ATGATTAATT


 


251
CTCGGCATAT CCTGATGGGG G.CGGCACTT GCCCCGCACC TGAAAGAAAT


 


301
ACCGCTGAAA AAAGCCGTGC CCGCACTGTT TTTTATGTGT GA






This corresponds to the amino acid sequence <SEQ ID 980; ORF 250.a>:










a250.pep




1
MTHISSPRNE FIRGIKESSP MLIGLLPWAL ILGMQGGQKG MSWLEMLLMT


 


51
GMNFAGGSEF ATVNLWAEPL PILLIATVTF MINSRHILMG XGTCPAPERN


 


101
TAEKSRARTV FYV*






m250/a250 94.6% identity in 111 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 981>:










g251.seq




1
atgcctgacc caatagggat tcttttcgct gccgtcgggg ttgatttttt


 


51
tgccgttgtt ttgagggggc gttttcaacg aataggcgcg gttggcatgt


 


101
tgataataat aatcctgatg gcggaggtcg gaaccaaaac ggtcgtaacc


 


151
gaggttgacg ctcaggttgt ggcggatttt ggcggtatcg aaggattttt


 


201
tgaatgccgc ctgcaagagc ctgtggcttt ccccgtaaat cacgcggtcg


 


251
gatttgtagt aggaagacgg cttgtcggca ctcgggcggc aatatttgtc


 


301
cgaaccgtcg gcggaacagt gcgtctgctg aaaatgattg tccaaaccga


 


351
tgccctgccg gtcgtaagag aggcgggcat aatccgccca agtgtcttta


 


401
tcggcattgg tatagacata ttccaaaccg tagcggcttt tggtgtgcgt


 


451
ctcgtcgtaa aacacgcccg taccgtattc cgcgcccacc tccgcaccgt


 


501
tttcaccgtt ggtaatcagc ccgctgtatt tgcggccgcc cgcgtatttg


 


551
ccgtagcctc ttatcgatcc gtatttttta ttttcatcaa aaaccgcctt


 


601
ggtcaggaat gccggaaccg tcatatcgcg cgtgtcgaaa gtttgctgcg


 


651
tgcgttcgag tatgccgccg atgtagtgcc gtttgttttc aaaacgaaaa


 


701
cccgggcgga acagccacga ccggctttcg tatga






This corresponds to the amino acid sequence <SEQ ID 982; ORF 251.ng>:










g251.pep




1
MPDPIGILFA AVGVDFFAVV LRGRFQRIGA VGMLIIIILM AEVGTKTVVT


 


51
EVDAQVVADF GGIEGFFECR LQEPVAFPVN HAVGFVVGRR LVGTRAAIFV


 


101
RTVGGTVRLL KMIVQTDALP VVREAGIIRP SVFIGIGIDI FQTVAAFGVR


 


151
LVVKHARTVF RAHLRTVFTV GNQPAVFAAA RVFAVASYRS VFFIFIKNRL


 


201
GQECRNRHIA RVESLLRAFE YAADVVPFVF KTKTRAEQPR PAFV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 983>:










m251.seq




1
ATGCGTGCTG CGGTAGTCGT AGCGCAAGCC CGCGCCGACA TCCGCCCACC


 


51
TGCCCAAACG GACATTGTCC CGAACTGCCG CGTAATAGCT TTTACCGTTG


 


101
ATGCTGCGCG GCGTGCAGTC CGTATAAGTA TTGTTGCCCA AGCGGCAGAT


 


151
TTGCCCCGTA ACGACATTTC CCCTGCCTAT GGTGACCCAA TAGGGGCTGG


 


201
TTTCACTGCC GTTGGGGCTG ATTTTTTTGC CGTTGTTTTG AGGGGGCGTG


 


251
TTCGACGAAT AGGCGCGGTT GGCATGTTGA TAATAATAAT CCTGATGGCG


 


301
GAGATTAGAG CCAAAGCGGT CAAACCCGAG ATTCACGCTC AGGTTGTGGC


 


351
GGATTTTGGC GGTATCGAAG GATTTTTTGA ATGCCGCCTG CAAGAGCCTG


 


401
TGGCTTTCCC CGTAAATCAC GCGATCGGAT TTGTAATAGG AAAACGGCTT


 


451
GTCGGCACTC GGGCGGCAAT ATTTGTCCGA ACCGTCGGCA GAACAGTGCG


 


501
TCTGCTGAAA ATGATTATCC AAACCGATGC CCTGCCGGTC GTAAGAGAGG


 


551
CGGGCATAAT CCGCCCAAGT GTCTTTATCG GCATTGGTAT AGACATATTC


 


601
CAAACCGTAG CGGCTTTTGG TGTGCGTCTC GTCGTAAAAC ACGCCCGTAC


 


651
CGTATTCCGC GCCCACCAGC GCACCGTTTT CGCCGTTGGT AAACAGTCCG


 


701
CCGTATTTGT GGTTGCCCGC GTATTTGCCG TTACCGGGCA AAGAACCCGC


 


751
CTGTTTTTTA TTTGCATCAA AAACCGCCTT GGTCAGGAAT GCCGGAACCG


 


801
TCATATCGCG CGTGTCGAAA GTTTGTTGCG TGTGTTCGAG TATGCCGCCG


 


851
ATGTAGTGCC GCTTATTCTC AAAACGAAAA CCCGGGCGGA ACAGCCACGA


 


901
CCGGCTTTCG TATGA






This corresponds to the amino acid sequence <SEQ ID 984; ORF 251>:










m251.pep




1
MRAAVVVAQA RADIRPPAQT DIVPNCRVIA FTVDAARRAV RISIVAQAAD


 


51
LPRNDISPAY GDPIGAGFTA VGADFFAVVL RGRVRRIGAV GMLIIIILMA


 


101
EIRAKAVKPE IHAQVVADFG GIEGFFECRL QEPVAFPVNH AIGFVIGKRL


 


151
VGTRAAIFVR TVGRTVRLLK MIIQTDALPV VREAGIIRPS VFIGIGIDIF


 


201
QTVAAFGVRL VVKHARTVFR AHQRTVFAVG KQSAVFVVAR VFAVTGQRTR


 


251
LFFICIKNRL GQECRNRHIA RVESLLRVFE YAADVVPLIL KTKTRAEQPR


 


301
PAFV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 251 shows 85.2% identity over a 243 aa overlap with a predicted ORF (ORF 251.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 985>:










a251.seq




1
ATGCGTGCTG CGGTAGTCGT AGCGCAACCC CGCGCCGACA TCCGCCCACC


 


51
TGCCCAAACG GACATTGTCC CGAACTGCCG CGTAATAGCT TTTGCCGTTG


 


101
ATGCTGCGCG GCGTGCAGTC CGTATAAGTA TTGTTGCCCA AGCGGCAGAT


 


151
TTGCCCCGTA ACCACATTTC CCCTGCCTAT GCTGACCCAA TAGGGTTGGT


 


201
CCTTGCCGCC GTTGGGGTTG GCGGTTTTAG GGGGCGTTTT CGACGAATAG


 


251
GCGCGGTTGG CATGTTGATA ATAATAATCC TGATGGCGGA GATTAGAGTC


 


301
AAAGCGGTCA AAACCGAGAT TCACGCTCAG GTTGTGGCGG ATTTTGGCGG


 


351
TATCGAAGGA TTTTTTGAAT GCCGCCTGCA AGAGCCTGTG GCTTTCCCCG


 


401
TAAATCACGC GGTCGGATTT GTAGTAGGAA AACGGCTTGT CGGCACTCGG


 


451
GCGGCAATAT TTGTCCGAAC CGTCGGCAGA ACAGTGCGTC TGCTGAAAAT


 


501
GATTGTCCAA ACCGATGCCC TGCCGGTCGT AAGAGAGGCG GGCATAATCC


 


551
ACCCAAGTGT CTTTATCGGC ATTGGTATAG ACATATTCCA AACCGTAGCG


 


601
GCTTTTGGTG TGCGTCTCGT CGTAAAACAC GCCCGTACCG TATTCCGCGC


 


651
CCACCAGCGC ACCGTTTTCG CCGTTGGTAA ACAGACCGCC GTATTTGTGG


 


701
TCGCCCGCGT ATTTGCCGTT GCCTCTTATC GGTCCGTATT TTCTATTTTC


 


751
ATCAAAAACC GCCTTGGTCA GGAATGCCGG AACCGTCATA TCGCGCGTGT


 


801
CGAAAGTTTG TTGCGTGTGT TCGAGTATGC CGCCGATGTA GTGCCGTTTG


 


851
TTTTCAAAAC GAAAACCCGG GCGGAACAGC CACGATCGGC TTTCGTATGA






This corresponds to the amino acid sequence <SEQ ID 986; ORF 251.a>:










a251.pep




1
MRAAVVVAQP RADIRPPAQT DIVPNCRVIA FAVDAARRAV RISIVAQAAD


 


51
LPRNHISPAY ADPIGLVLAA VGVGGFRGRF RRIGAVGMLI IIILMAEIRV


 


101
KAVKTEIHAQ VVADFGGIEG FFECRLQEPV AFPVNHAVGF VVGKRLVGTR


 


151
AAIFVRTVGR TVRLLKMIVQ TDALPVVREA GIIHPSVFIG IGIDIFQTVA


 


201
AFGVRLVVKH ARTVFRAHQR TVFAVGKQTA VFVVARVFAV ASYRSVFSIF


 


251
IKNRLGQECR NRHIARVESL LRVFEYAADV VPFVFKTKTR AEQPRSAFV*






m251/a251 88.5% identity in 304 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 987>:










g253.seq




1
atgatcgaca gggaccgtat gttgcgggac acgttggaac gtgtgcgtgc


 


51
ggggtcgttc tggttatggg tggtggtggc atcgatgatg tttaccgccg


 


101
gattttcagg cacttatctt ctgatggaca atcaggggct gaatttcttt


 


151
ttagttttgg cgggagtgtt gggcatgaat acgctgatgc tggcagtatg


 


201
gttggcaacg ttgttcctgc gcgtgaaagt gggacggttt ttcagcagtc


 


251
cggcgacgtg gtttcggggc aaaggccctg taaatcaggc ggtgttgcgg


 


301
ctgtatgcgg accagtggcg gcaaccttcg gtacgatgga aaataggcgc


 


351
aacggcgcac agcttgtggc tctgcacgct gctcggaatg ctggtgtcgg


 


401
tattgctgct gcttttggtg cggcaatata cgttcaactg ggaaagcacg


 


451
ctgttgagca atgccgcttc ggtacgcgcg gtggaaatgt tggcatggct


 


501
gccgtcgaaa ctcggtttcc ctgtccccga tgcgcgggcg gtcatcgaag


 


551
gtcgtctgaa cggcaatatt gccgatgcgc gggcttggtc ggggctgctg


 


601
gtcggcagta tcgtctgcta cggcatcctg ccgcgcctct tggcttgggt


 


651
agtgtgtaaa atccttttga aaacaagcga aaacggattg gatttggaaa


 


701
aaacctatta tcaggcggtc atccgccgct ggcagaacaa aatcaccgat


 


751
gcggatacgc gtcgggaaac cgtgtccgcc gtttcgccga aaatcgtctt


 


801
gaacgatgcg ccgaaatggg cgctcatgct ggagaccgag tggcaggacg


 


851
gccaatggtt cgagggcagg ctggcgcagg aatggctgga taagggcgtt


 


901
gccgccaatc gggaacaggt tgccgcgctg gagacagagc tgaagcagaa


 


951
accggcgcaa ctgcttatcg gcgtacgcgc ccaaactgtg ccggaccggg


 


1001
gcgtgctgcg gcagattgtg cggctttcgg aagcggcgca gggcggcgcg


 


1051
gtggtgcagc ttttggcgga acaggggctt tcagacgacc tttcggaaaa


 


1101
gctggaacat tggcgtaacg cgctgaccga atgcggcgcg gcgtggcttg


 


1151
agcctgacag ggtggcgcag gaaggccgtt tgaaagacca ataa






This corresponds to the amino acid sequence <SEQ ID 988; ORF 253.ng>:










g253.pep




1
MIDRDRMLRD TLERVRAGSF WLWVVVASMM FTAGFSGTYL LMDNQGLNFF


 


51
LVLAGVLGMN TLMLAVWLAT LFLRVKVGRF FSSPATWFRG KGPVNQAVLR


 


101
LYADQWRQPS VRWKIGATAH SLWLCTLLGM LVSVLLLLLV RQYTFNWEST


 


151
LLSNAASVRA VEMLAWLPSK LGFPVPDARA VIEGRLNGNI ADARAWSGLL


 


201
VGSIVCYGIL PRLLAWVVCK ILLKTSENGL DLEKTYYQAV IRRWQNKITD


 


251
ADTRRETVSA VSPKIVLNDA PKWALMLETE WQDGQWFEGR LAQEWLDKGV


 


301
AANREQVAAL ETELKQKPAQ LLIGVRAQTV PDRGVLRQIV RLSEAAQGGA


 


351
VVQLLAEQGL SDDLSEKLEH WRNALTECGA AWLEPDRVAQ EGRLKDQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 989>:










m253.seq




1
ATGATTGACA GGAACCGTAT GCTGCGGGAG ACGTTGGAAC GTGTGCGTGC


 


51
GGGGTCGTTC TGGTTGTGGG TGGTGGCGGC GACGTTTGCA TTTTTTACCG


 


101
GTTTTTCAGT CACTTATCTT CTAATGGACA ATCAGGGTCT GAATTTCTTT


 


151
TTGGTTTTGG CGGGCGTGTT GGGCATGAAT ACGCTGATGC TGGCAGTATG


 


201
GTTGGCAATG TTGTTCCTGC GTGTGAAAGT GGGGCGTTTT TTCAGCAGTC


 


251
CGGCGACGTG GTTTCGGGGC AAAGACCCTG TAAATCAGGC GGTGTTGCGG


 


301
CTGTATGCGG ACGAGTGGCG GCAACCTTCG GTACGTTGGA AAATAGGCGC


 


351
AACGTCGCAC AGCCTGTGGC TCTGCACGCT GCTCGGAATG CTGGTGTCGG


 


401
TATTGTTGCT GCTTTTGGTG CGGCAATATA CGTTCAACTG GGAAAGCACG


 


451
CTGTTGAGCA ATGCCGCTTC GGTACGCGCG GTGGAAATGT TGGCATGGCT


 


501
GCCGTCGAAA CTCGGTTTCC CTGTCCCCGA TGCGCGGGCG GTCATCGAAG


 


551
GCCGTCTGAA CGGCAATATT GCCGATGCGC GGGCTTGGTC GGGGCTGCTG


 


601
GTCGGCAGTA TCGCCTGCTA CGGCATCCTG CCGCGCCTGC TGGCTTGGGT


 


651
AGTGTGTAAA ATCCTTTTGA AAACAAGCGA AAACGGATTG GATTTGGAAA


 


701
AGCCCTATTA TCAGGCGGTC ATCCGCCGCT GGCAGAACAA AATCACCGAT


 


751
GCGGATACGC GTCGGGAAAC CGTGTCCGCC GTTTCACCGA AAATCATCTT


 


801
GAACGATGCG CCGAAATGGG CGGTCATGCT GGAGACCGAG TGGCAGGACG


 


851
GCGAATGGTT CGAGGGCAGG CTGGCGCAGG AATGGCTGGA TAAGGGCGTT


 


901
GCCACCAATC GGGAACAGGT TGCCGCGCTG GAGACAGAGC TGAAGCAGAA


 


951
ACCGGCGCAA CTGCTTATCG GCGTGCGCGC CCAAACTGTG CCGGACCGCG


 


1001
GCGTGTTGCG GCAGATTGTC CGACTCTCGG AAGCGGCGCA GGGCGGCGCG


 


1051
GTGGTGCAGC TTTTGGCGGA ACAGGGGCTT TCAGACGACC TTTCGGAAAA


 


1101
GCTGGAACAT TGGCGTAACG CGCTGGCCGA ATGCGGCGCG GCGTGGCTTG


 


1151
AGCCTGACAG GGCGGCGCAG GAAGGGCGTT TGAAAGACCA ATAA






This corresponds to the amino acid sequence <SEQ ID 990; ORF 253>:










m253.pep




1
MIDRNRMLRE TLERVRAGSF WLWVVAATFA FFTGFSVTYL LMDNQGLNFF


 


51
LVLAGVLGMN TLMLAVWLAM LFLRVKVGRF FSSPATWFRG KDPVNQAVLR


 


101
LYADEWRQPS VRWKIGATSH SLWLCTLLGM LVSVLLLLLV RQYTFNWEST


 


151
LLSNAASVRA VEMLAWLPSK LGFPVPDARA VIEGRLNGNI ADARAWSGLL


 


201
VGSIACYGIL PRLLAWVVCK ILLKTSENGL DLEKPYYQAV IRRWQNKITD


 


251
ADTRRETVSA VSPKIILNDA PKWAVMLETE WQDGEWFEGR LAQEWLDKGV


 


301
ATNREQVAAL ETELKQKPAQ LLIGVRAQTV PDRGVLRQIV RLSEAAQGGA


 


351
VVQLLAEQGL SDDLSEKLEH WRNALAECGA AWLEPDRAAQ EGRLKDQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 253 shows 94.7% identity over a 397 aa overlap with a predicted ORF (ORF 253.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 991>:










a253.seq




1
ATGATCGACA GGAACCGTAT GCTGCGGGAG ACGTTGGAAC GTGTGCGTGC


 


51
GGGGTCGTTC TGGTTGTGGG TGGCGGCGGC GACGTTTGCG TTTTTTACCG


 


101
GTTTTTCAGT TACTTATCTT CTAATGGACA ATCAGGGTCT GAATTTCTTT


 


151
TTGGTTTTGG CGGGCGTGTT GGGCATGAAT ACGCTGATGC TGGCAGTATG


 


201
GTTGGCAATG TTGTTCCTGC GCGTGAAAGT GGGGCGTTTT TTCAGCAGTC


 


251
CGGCGACGTG GTTTCGGGGC AAAGACCCTG TCAATCAGGC GGTGTTGCGG


 


301
CTGTATGCGG ACGAGTGGCG GCAACCTTCG GTACGTTGGA AAATAGGCGC


 


351
AACGTCGCAC AGCCTGTGGC TCTGCACGCT GCTCGGAATG CTGGTGTCGG


 


401
TATTGTTGCT GCTTTTGGTG CGGCAATATA CGTTCAACTG GGAAAGCACG


 


451
CTGTTGGGCG ATTCGTCTTC GGTACGGCTG GTGGAAATGT TGGCATGGCT


 


501
GCCTGCGAAA CTGGGTTTTC CCGTGCCTGA TGCGCGGGCG GTCATCGAAG


 


551
GTCGTCTGAA CGGCAATATT GCCGATGCGC GGGCTTGGTC GGGGCTGCTG


 


601
GTCGGCAGTA TCGCCTGCTA CGGCATCCTG CCGCGCCTCT TGGCTTGGGC


 


651
GGTATGCAAA ATCCTTTTGA AAACAAGCGA AAACGGCTTG GATTTGGAAA


 


701
AGCCCTATTA TCAGGCGGTC ATCCGCCGCT GGCAGAACAA AATCACCGAT


 


751
GCGGATACGC GTCGGGAAAC CGTGTCCGCC GTTTCGCCGA AAATCGTCTT


 


801
GAACGATGCG CCGAAATGGG CGGTCATGCT GGAGACCGAA TGGCAGGACG


 


851
GCGAATGGTT CGAGGGCAGG CTGGCGCAGG AATGGCTGGA TAAGGGCGTT


 


901
GCCGCCAATC GGGAACAGGT TGCCGCGCTG GAGACAGAGC TGAAGCAGAA


 


951
ACCGGCGCAA CTGCTTATCG GCGTGCGCGC CCAAACTGTG CCCGACCGCG


 


1001
GCGTGTTGCG GCAGATCGTC CGACTTTCGG AAGCGGCGCA GGGCGGCGCG


 


1051
GTGGTGCAGC TTTTGGCGGA ACAGGGGCTT TCAGACGACC TTTCGGAAAA


 


1101
GCTGGAACAT TGGCGTAACG CGCTGACCGA ATGCGGCGCG GCGTGGCTGG


 


1151
AACCCGACAG AGCGGCGCAG GAAGGCCGTC TGAAAACCAA CGACCGCACT


 


1201
TGA






This corresponds to the amino acid sequence <SEQ ID 992; ORF 253.a>:










a253.pep




1
MIDRNRMLRE TLERVRAGSF WLWVAAATFA FFTGFSVTYL LMDNQGLNFF


 


51
LVLAGVLGMN TLMLAVWLAM LFLRVKVGRF FSSPATWFRG KDPVNQAVLR


 


101
LYADEWRQPS VRWKIGATSH SLWLCTLLGM LVSVLLLLLV RQYTFNWEST


 


151
LLGDSSSVRL VEMLAWLPAK LGFPVPDARA VIEGRLNGNI ADARAWSGLL


 


201
VGSIACYGIL PRLLAWAVCK ILLKTSENGL DLEKPYYQAV IRRWQNKITD


 


251
ADTRRETVSA VSPKIVLNDA PKWAVMLETE WQDGEWFEGR LAQEWLDKGV


 


301
AANREQVAAL ETELKQKPAQ LLIGVRAQTV PDRGVLRQIV RLSEAAQGGA


 


351
VVQLLAEQGL SDDLSEKLEH WRNALTECGA AWLEPDRAAQ EGRLKTNDRT


 


401
*






m253/a253 97.2% identity in 395 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 993>:










g254.seq




1
atgtatgcag gcgaacgctt caatacttac agccatttga gcggtttgat


 


51
tctggcggcg gcaggtttga tgctgatgct gctgaaaacc ataggacacg


 


101
gggacggata ccgtatcttc agcgtatcgg tttacggcat cagccttctt


 


151
ctgctctatt tgagttcctc gctgtaccac ggaattgcag ccggaaaact


 


201
gaaaagcatt ttgaaaaaaa ccgaccactg catgatttat gtgctgattg


 


251
ccggaagcta cacaccgttt gcactggttt ctttgagaaa cgggccgggc


 


301
tggacggtat tttcactgtc ctggctgctg gcggctgcag gaatcgcaca


 


351
agaactcacc atcggacgga aaagcgaaaa acgtctgctg tctattgcga


 


401
tttatatcgt aatgggctgg atggtcttgg cggtaatgaa atccctgaca


 


451
gcctcactcc cgccggcagg actggcttgg ctggcggcag gcggtatgct


 


501
gtacagcgtc ggcatttact ggtttgtaaa cgatgaaaaa atccgacacg


 


551
ggcacggaat ctggcatctg ttcgtattgg gcggcagcat aacccaattt


 


601
gtcagcgtgt acggttatgt aatctga






This corresponds to the amino acid sequence <SEQ ID 994; ORF 254.ng>:










g254.pep




1
MYAGERFNTY SHLSGLILAA AGLMLMLLKT IGHGDGYRIF SVSVYGISLL


 


51
LLYLSSSLYH GIAAGKLKSI LKKTDHCMIY VLIAGSYTPF ALVSLRNGPG


 


101
WTVFSLSWLL AAAGIAQELT IGRKSEKRLL SIAIYIVMGW MVLAVMKSLT


 


151
ASLPPAGLAW LAAGGMLYSV GIYWFVNDEK IRHGHGIWHL FVLGGSITQF


 


201
VSVYGYVI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 995>:









m254.seq (partial)










1
..GTATCGGTTT ACGGCATCAG CCTTCTTCTG CTCTATTTGA GTTCCTGGCT



 


51
  GTACCACGGA ATTGCAGCCG GAAAACTGAA AAGCATTTTG AAAAAAACCG


 


101
  ACCACTGCAT GATTTATGTG CTGATTGCCG GAAGCTACAC ACCGTTTGCA


 


151
  CTGGTTTCTT TGAGAAACGG GCCGGGCTGG ACGGTATTTT CACTGTCCTG


 


201
  GCTGCTGGCG GCTGCAGGAA TCGCACAAGA ACTCACCATC GGACGGAAAA


 


251
  GCGAAAAACG TCTGCTGTCT ATTGTGATTT ATGTCGTCAT GGGTTGGATG


 


301
  GTCTTGGCGG TAATGAAATC CCTGACAGCC TCACTCCCGT CGGCAGGACT


 


351
  GGCTTGGCTG GCGGCAGGCG GTATGCTGTA CAGTGTCGGC ATTTACTGGT


 


401
  TTGTAAACGA TGAAAAAATC CGACACGGGC ACGGAATCTG GCATCTGTTC


 


451
  GTATTGGGCG GCAGCATCAC CCAATTTGTC AGCGTGTACG GTTACGTAAT


 


501
  CTGA






This corresponds to the amino acid sequence <SEQ ID 996; ORF 254>:









m254.pep (partial)










1
..VSVYGISLLL LYLSSWLYHG IAAGKLKSIL KKTDHCMIYV LIAGSYTPFA



 


51
  LVSLRNGPGW TVFSLSWLLA AAGIAQELTI GRKSEKRLLS IVIYVVMGWM


 


101
  VLAVMKSLTA SLPSAGLAWL AAGGMLYSVG IYWFVNDEKI RHGHGIWHLF


 


151
  VLGGSITQFV SVYGYVI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 254 shows 97.6% identity over a 167 aa overlap with a predicted ORF (ORF 254.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 997>:










a254.seq




1
ATGTATACAG GCGAACGCTT CAATACTTAC AGCCATTTGA GCGGTTTGAT


 


51
TCTGGCGGCG GCAGGTTTGG CGCTGATGCT GCTGAAAACC ATAGGACACG


 


101
GGGACGGCTA CCGTATCTTC AGCGTATCGG TTTACGGCAT CAGCCTTCTT


 


151
CTGCTCTATT TGAGTTCCTC GCTGTACCAC GGAATTGCAG CCGGAAAACT


 


201
GAAAAGCATT TTGAAAAAAA CCGACCACTG CATGATTTAT GTGCTGATTG


 


251
CCGGAAGCTA CACACCGTTT GCACTGGTTT CTTTGAGAAA CGGGCCGGGC


 


301
TGGACGGTAT TTTCACTGTC CTGGCTGCTG GCGGCTGCAG GAATCGCACA


 


351
AGAACTCACC ATTGGACGGA AAAGCGAAAA ACGACTGCTG TCTATTGCGA


 


401
TTTATATCGT AATGGGCTGG ATGGTCTTGG CGGTAATGAA ATCCCTGACA


 


451
GCCTCACTCC CGCCGGCAGG ACTGGCTTGG CTGGCGGCAG GCGGTATGCT


 


501
GTACAGCGTC GGCATTTACT GGTTTGTAAA CGATGAAAAA ATCCGACACG


 


551
GGCACGGAAT CTGGCATCTG TTCGTATTGG GCGGCAGCAT CACCCAATTT


 


601
GTCAGCGTGT ACGGTTACGT AATCTGA






This corresponds to the amino acid sequence <SEQ ID 998; ORF 254.a>:










a254.pep




1
MYTGERFNTY SHLSGLILAA AGLALMLLKT IGHGDGYRIF SVSVYGISLL


 


51
LLYLSSSLYH GIAAGKLKSI LKKTDHCMIY VLIAGSYTPF ALVSLRNGPG


 


101
WTVFSLSWLL AAAGIAQELT IGRKSEKRLL SIAIYIVMGW MVLAVMKSLT


 


151
ASLPPAGLAW LAAGGMLYSV GIYWFVNDEK IRHGHGIWHL FVLGGSITQF


 


201
VSVYGYVI*






m254/a254 97.6% identity in 167 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 999>:










g255.seq




1
atggttggac aggaagcctt gcggggtcag ttcgtcgccg tgttcgctgc


 


51
cgcgttgcgt tacgctgtca aaacctgcgc cgatttccac gcctttgacg


 


101
gcgttgatgc ccatcatcgc gtaggcgatt tcggcatcga ggcggtcgaa


 


151
aacgggttcg cccaaaccga cggggacgtt ggcggcttcg atatgcagtt


 


201
tcgcgccgac ggaatccaag gatttgcgca caccgtccat atagtgttcc


 


251
agttcggcga tttggctttg gttggcggca aaaaaaggat tttgggaaat


 


301
gtgttcgctg ccttcaaacc ggattttttt ttcgccgact tgggtaacgt


 


351
aggcggtgat ttccgtgccg aatttttctt tcagccattt tttggcaacg


 


401
gctccggcgg caacgcgggc tgcggtttcg cgggcggaac tcctgccgcc


 


451
gccccggtag tcgcgcgtac cgtatttgtg ccaataggta tagtcggcgt


 


501
gtccggggcg gaaggcggtg gcgatgtcgc cgtagtcttc gctgcgctgg


 


551
tcggtgttgc ggattag






This corresponds to the amino acid sequence <SEQ ID 1000; ORF 255.ng>:










g255.pep




1
MVGQEALRGQ FVAVFAAALR YAVKTCADFH AFDGVDAHHR VGDFGIEAVE


 


51
NGFAQTDGDV GGFDMQFRAD GIQGFAHTVH IVFQFGDLAL VGGKKRILGN


 


101
VFAAFKPDFF FADLGNVGGD FRAEFFFQPF FGNGSGGNAG CGFAGGTPAA


 


151
APVVARTVFV PIGIVGVSGA EGGGDVAVVF AALVGVAD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1001>:










m255.seq




1
GTGGTTGGAC AGGAAGCCTT GCGGGGTCAG TTCGTCGCCG TGTTCGCTGC


 


51
CGCGTTGCGT TACGCTGTCA AAACCTGCGC CGATTTCCAC GCCTTTGACG


 


101
GCGTTGATGC CCATCATCGC GTAGGCGATT TCGGCATCGA GGCGGTCAAA


 


151
AACAGGTTCG CCCAAGCCGA CAGGGACATT GGCTGCTTCG ATATGCAGCT


 


201
TCGCGCCGAC GGAATCCAAG GATTTGCGCA CGCTGTCCAT ATAGTTTTCC


 


251
AGCTCGGCAA TTTGGCTATG GTTGGCGGCA AAAAAAGGAT TTTGGGAAAT


 


301
GTGTTCGCAG CCTTCAAACC GGATTTCTTT TTCGCCGACT TGGGTAACGT


 


351
AGGCGGTGAT TTCCGTGCCG AATTTTTCTT TCAACCATTT TTTGGCAACG


 


401
GCTCCGGCAG CAACGCGGGC GGCGGTTTCA CGGGCGGAGC TCCTGCCGCC


 


451
GCCGCGGTAG TCGCGCGTGC CGTATTTGTG CCAATAGGTA TAGTCGGCGT


 


501
GGCCGGGGCG GAAGCTGGTG GCGATGTTGC CGTAGTCTTT GCTGCGCTGG


 


551
TCGGTATTGC GGATTAA






This corresponds to the amino acid sequence <SEQ ID 1002; ORF 255>:










m255.pep




1
VVGQEALRGQ FVAVFAAALR YAVKTCADFH AFDGVDAHHR VGDFGIEAVK


 


51
NRFAQADRDI GCFDMQLRAD GIQGFAHAVH IVFQLGNLAM VGGKKRILGN


 


101
VFAAFKPDFF FADLGNVGGD FRAEFFFQPF FGNGSGSNAG GGFTGGAPAA


 


151
AAVVARAVFV PIGIVGVAGA EAGGDVAVVF AALVGIAD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 255 shows 88.8% identity over a 188 aa overlap with a predicted ORF (ORF 255.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1003>:










a255.seq




1
GTGGTTGGAC AGGAAGCCTT GCGGGGTGAG TTCGTCGCCG TGTTCGCTGC


 


51
CGCGTTGCGT TACGCTGTCA AAACCTGCGC CGATTTCCAC GCCTTTGACG


 


101
GCGTTGATGC CCATCATGGC GTAGGCGATT TCGGCATCGA GGCGGTCGAA


 


151
TACGGGTTCG CCCAAGCCGA CGGGGACGTT GGCGGCTTCA ATATGCAGCT


 


201
TCGCGCCGAC GGAATCCAAG GATTTGCGCA CGCTGTCCAT ATAGTTTTCC


 


251
AGCTCGGCAA TTTGGCTATG GTTGGCGGCA AAAAAAGGAT TTTGGGAAAT


 


301
GTGTTCGCAG CCTTCAAACC GGATTTCTTT TTCGCCGACT TGGGTAACGT


 


351
AGGCGGTGAT TTCCGTGCCG AATTTTTCTT TCAACCATTT TTTGGCAACG


 


401
GCTCCGGCGG CAACGCGGGC GGCGGTTTCG CGGGCGGAAC TCCTGCCGCC


 


451
GCCCCGGTAG TCGCGCGTGC CGTATTTGTG CCAATAGGTA TAGTCGGCGT


 


501
GGCCGGGGCG GAAGCTGGTG GCGATGTTGC CGTAGTCTTT GCTGCGCTGG


 


551
TCGGTATTGC GGATTAA






This corresponds to the amino acid sequence <SEQ ID 1004; ORF 255.a>:










a255.pep




1
VVGQEALRGE FVAVFAAALR YAVKTCADFH AFDGVDAHHG VGDFGIEAVE


 


51
YGFAQADGDV GGFNMQLRAD GIQGFAHAVH IVFQLGNLAM VGGKKRILGN


 


101
VFAAFKPDFF FADLGNVGGD FRAEFFFQPF FGNGSGGNAG GGFAGGTPAA


 


151
APVVARAVFV PIGIVGVAGA EAGGDVAVVF AALVGIAD*






m255/a255 93.1% identity in 188 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1005>:










g256.seq




1
atgctcgcgg tacgcaatcg gggttggcac ggcgcagtcg tccatttccg


 


51
cagctgcggc ggcgtagcga acaccgcccc ggtgttctac cacttgggtg


 


101
ataccgccga aatcgccttt gctttggaca cgctcaccgc gcgttaccgt


 


151
gaaatatacg ccgtcggcgt atcgctgggc ggcaacgcgc cggcaaaata


 


201
tttgggcgaa cagggcaaaa aggcattgcc gcacgcctcg gccgccgtat


 


251
ccgcccccgt tgatgcagag gcggcaggca gccgcttcga cagcggcatc


 


301
acgcggctgc tctacacgcg ctacttcctc cgcacactga tacccaaagc


 


351
acgttcgctc caaggttttc agacggcatt tgccgcaggg tgcaaaacac


 


401
tgggcgagtt tgacgaccgt ttcaccgcac cgctgcacgg ctttgccgac


 


451
cggcacgact actaccgcca aacttcctgc aaaccgctgc tcaaacacgt


 


501
tgccaaaccg ctgctcctgc tcaatgccgc caacgacccc ttcctgccgc


 


551
ccgaagccct gccccgtgca gacgaagcgt ccgaagccgt taccctgttc


 


601
caacctgcac acggcgggca cgccggcttt gtcagcagca ccggcggcag


 


651
gctgcacctg caatggctgc cgcagaccgt cctgtcctat tttgacagct


 


701
tccgcacaaa caggcgttaa






This corresponds to the amino acid sequence <SEQ ID 1006; ORF 256.ng>:










g256.pep




1
MLAVRNRGWH GAVVHFRSCG GVANTAPVFY HLGDTAEIAF ALDTLTARYR


 


51
EIYAVGVSLG GNAPAKYLGE QGKKALPHAS AAVSAPVDAE AAGSRFDSGI


 


101
TRLLYTRYFL RTLIPKARSL QGFQTAFAAG CKTLGEFDDR FTAPLHGFAD


 


151
RHDYYRQTSC KPLLKHVAKP LLLLNAANDP FLPPEALPRA DEASEAVTLF


 


201
QPAHGGHAGF VSSTGGRLHL QWLPQTVLSY FDSFRTNRR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1007>:










m256.seq




1
ATGCTTGCGG TACGCGATCG GGGTTGGCAC GGCGTAGTCG TCCATTTCCG


 


51
CAGCTGCGGC GGCATTGCCA ACACCGCTCC GGTGTTCTAC CA.CTtGGCG


 


101
ATACCGCCGA AATCGCCTTT ACTTTGGACA CGTTCGCCGC GCGTTACCGT


 


151
GAAAtATACG CCGTCGGCGT ATCGCTGGGC GGCAACGCGC TGGCAAAATA


 


201
TTTGGGCGAA CAGGGCAAAA AGGCATTGCC GCAAGCCGCT GCCGTCATCT


 


251
CCGCCCCCGT CGATGCAGAG GCGGCAGGCA GACGCTTCGA CAGCGGCATC


 


301
ACGCGGCTGC TCTACACGCG CTACTTCCTC CGCACCCTGA TACCCAAAGC


 


351
AAAATCGCTC CAAGGTTTTC AGACGGCATT TGCCGCAGGG TGCAAAACAC


 


401
TGGGCGAGTT TGACGACCGC TTCACCGCAC CGCTGCACGG CTTTGCCGAC


 


451
CGGCACGACT ACTACCGCCA AACTTCCTGC AAACCGCTGC TCAAACACGT


 


501
TGCCAAACCG CTGCTCCTGC TCAATGCCGT CAACGACCCC TTCCTGCCGC


 


551
CCGAAGCCGT GCCCCGCGCA GACGAAGTAT CCGAAGCCGT TACCCTGTTC


 


601
CAGCCGGCAT ATGGTGGTCA TGTCGGCTTT GTCAGCAGCA CCGGCGGCAG


 


651
GCTGCACCTG CAATGGCTGC CGCAGACCGT CCTGTCCTAT TTCGACAGCT


 


701
TCCGCACAAA CAGGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1008; ORF 256>:










m256.pep




1
MLAVRDRGWH GVVVHFRSCG GIANTAPVFY XLGDTAEIAF TLDTFAARYR


 


51
EIYAVGVSLG GNALAKYLGE QGKKALPQAA AVISAPVDAE AAGRRFDSGI


 


101
TRLLYTRYFL RTLIPKAKSL QGFQTAFAAG CKTLGEFDDR FTAPLHGFAD


 


151
RHDYYRQTSC KPLLKHVAKP LLLLNAVNDP FLPPEALPRA DEVSEAVTLF


 


201
QPAYGGHVGF VSSTGGRLHL QWLPQTVLSY FDSFRTNRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 256 shows 92.9% identity over a 239 aa overlap with a predicted ORF (ORF 256.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1009>:










a256.seq




1
ATGCTCGCGG TACGCGATCG GGGTTGGAAC GGCGTAGTCG TCCATTTCCG


 


51
CAGCTGCGGC GGCGTAGCGA ACACCGCCCC GGTGTTCTAC CACTTGGGCG


 


101
ATACCGCCGA AATTGCCTTT ACTTTGGACA CGCTCGCCGC GCGTTACCGT


 


151
GAAATATACG CCGTCGGCGT ATCGCTGGGC GGCAACGCGC TGGCAAAATA


 


201
TTTGGGCGAA CAGGGCGAAA ACGCGCTGCC GCAAGCCGCC GCCGTCATCT


 


251
CCGAAGCCGT CGATGCAGAG GCGGCAGGCA ACCGCTTCGA CAGCGGCATC


 


301
ACACGGCTGC TCTACACGCG CTACTTCCTC CGCACACTGA TACCCAAAGC


 


351
ACGGTCGCTC CAAGGTTTTC AGACGGCATT TGCCGCAGGG TGCAAAACAC


 


401
TGGGCGAGTT TGACGACCGT TTCACCGCAC CGCTGCACGG CTTTGCCGAT


 


451
CGGCACGACT ACTACCGCCA AACTTCCTGC AAACCGCTGC TCAAACACGT


 


501
TGCCAAACCG CTGCTCCTGC TCAATGCCGT CAACGACCCC TTCCTGCCGC


 


551
CCGAAGCGCT GCCCCGCGCA GACGAAGTGT CCGAAGCCGT TACCCTGTTC


 


601
CAGCCGACAC ACGGTGGTCA TGTCGGCTTT GTCGGCAGCA CCGGCGGCAG


 


651
GCTGCACCTG CAATGGTTGC CGCAGACCGT CCTGTCCTAT TTCGACAGCT


 


701
TCCGCACAAA CAGGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1010; ORF 256.a>:










a256.pep




1
MLAVRDRGWN GVVVHFRSCG GVANTAPVFY HLGDTAEIAF TLDTLAARYR


 


51
EIYAVGVSLG GNALAKYLGE QGENALPQAA AVISAPVDAE AAGNRFDSGI


 


101
TRLLYTRYFL RTLIPKARSL QGFQTAFAAG CKTLGEFDDR FTAPLHGFAD


 


151
RHDYYRQTSC KPLLKHVAKP LLLLNAVNDP FLPPEALPRA DEVSEAVTLF


 


201
QPTHGGHVGF VGSTGGRLHL QWLPQTVLSY FDSFRTNRR*






m256/a256 95.4% identity in 239 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1011>:










g256-1.seq




1
ATGATTTTGA CACCGCCGGA CACGCCCTTT TTCCTCCGCA ACGGCAATGC


 


51
CGACACGATT GCCGCCAAAT TCCTGCAACA CCCCGCACCC GCATACCGCC


 


101
GCGAGATGCT TCCCGACAGC ACGGGTAAAA CCAAAACCGC CTACGACTTT


 


151
TCAGCAGGCG GCATTTCGCC CGATGCGCCG CTGGTCGTGC TGTTTCACGG


 


201
TTTGGAAGGA AGCAGCCGCA GCCATTACGC GGTCGAACTG ATGCTCGCGG


 


251
TACGCAATCG GGGTTGGCAC GGCGCAGTCG TCCATTTCCG CAGCTGCGGC


 


301
GGCGTAGCGA ACACCGCCCC GGTGTTCTAC CACTTGGGTG ATACCGCCGA


 


351
AATCGCCTTT GCTTTGGACA CGCTCACCGC GCGTTACCGT GAAATATACG


 


401
CCGTCGGCGT ATCGCTGGGC GGCAACGCGC CGGCAAAATA TTTGGGCGAA


 


451
CAGGGCAAAA AGGCATTGCC GCACGCCTCG GCCGCCGTAT CCGCCCCCGT


 


501
TGATGCAGAG GCGGCAGGCA GCCGCTTCGA CAGCGGCATC ACGCGGCTGC


 


551
TCTACACGCG CTACTTCCTC CGCACACTGA TACCCAAAGC ACGTTCGCTC


 


601
CAAGGTTTTC AGACGGCATT TGCCGCAGGG TGCAAAACAC TGGGCGAGTT


 


651
TGACGACCGT TTCACCGCAC CGCTGCACGG CTTTGCCGAC CGGCACGACT


 


701
ACTACCGCCA AACTTCCTGC AAACCGCTGC TCAAACACGT TGCCAAACCG


 


751
CTGCTCCTGC TCAATGCCGC CAACGACCCC TTCCTGCCGC CCGAAGCCCT


 


801
GCCCCGTGCA GACGAAGCGT CCGAAGCCGT TACCCTGTTC CAACCTGCAC


 


851
ACGGCGGGCA CGCCGGCTTT GTCAGCAGCA CCGGCGGCAG GCTGCACCTG


 


901
CAATGGCTGC CGCAGACCGT CCTGTCCTAT TTTGACAGCT TCCGCACAAA


 


951
CAGGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1012; ORF 256-1.ng>:










g256-1.pep




1
MILTPPDTPF FLRNGNADTI AAKFLQHPAP AYRREMLPDS TGKTKTAYDF


 


51
SAGGISPDAP LVVLFHGLEG SSRSHYAVEL MLAVRNRGWH GAVVHFRSCG


 


101
GVANTAPVFY HLGDTAEIAF ALDTLTARYR EIYAVGVSLG GNAPAKYLGE


 


151
QGKKALPHAS AAVSAPVDAE AAGSRFDSGI TRLLYTRYFL RTLIPKARSL


 


201
QGFQTAFAAG CKTLGEFDDR FTAPLHGFAD RHDYYRQTSC KPLLKHVAKP


 


251
LLLLNAANDP FLPPEALPRA DEASEAVTLF QPAHGGHAGF VSSTGGRLHL


 


301
QWLPQTVLSY FDSFRTNRR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1010>:










m256-1.seq




1
ATGATTTTAA CACCGCCGGA CACGCCCTTT TTCCTCCGCA ACGGCAATGC


 


51
CGACACGATT GCCGCCAAAT TCCTGCAACG CCCCGCGCCC GCATACCGCC


 


101
GAGAGCTGCT TCCCGACAGC ACGGGTAAAA CCAAAGTCGC CTACGACTTT


 


151
TCAGACGGCA TTTCGCCCGA TGCGCCGCTG GTCGTGCTGT TTCACGGTTT


 


201
GGAAGGAAGC AGCCGCAGCC ATTACGCGGT CGAACTGATG CTTGCGGTAC


 


251
GCGATCGGGG TTGGCACGGC GTAGTCGTCC ATTTCCGCAG CTGCGGCGGC


 


301
ATTGCCAACA CCGCTCCGGT GTTCTACCAC TTGGGCGATA CCGCCGAAAT


 


351
CGCCTTTACT TTGGACACGT TCGCCGCGCG TTACCGTGAA ATATACGCCG


 


401
TCGGCGTATC GCTGGGCGGC AACGCGCTGG CAAAATATTT GGGCGAACAG


 


451
GGCAAAAAGG CATTGCCGCA AGCCGCTGCC GTCATCTCCG CCCCCGTCGA


 


501
TGCAGAGGCG GCAGGCAGAC GCTTCGACAG CGGCATCACG CGGCTGCTCT


 


551
ACACGCGCTA CTTCCTCCGC ACCCTGATAC CCAAAGCAAA ATCGCTCCAA


 


601
GGTTTTCAGA CGGCATTTGC CGCAGGGTGC AAAACACTGG GCGAGTTTGA


 


651
CGACCGCTTC ACCGCACCGC TGCACGGCTT TGCCGACCGG CACGACTACT


 


701
ACCGCCAAAC TTCCTGCAAA CCGCTGCTCA AACACGTTGC CAAACCGCTG


 


751
CTCCTGCTCA ATGCCGTCAA CGACCCCTTC CTGCCGCCCG AAGCCCTGCC


 


801
CCGCGCAGAC GAAGTATCCG AAGCCGTTAC CCTGTTCCAG CCGGCATATG


 


851
GTGGTCATGT CGGCTTTGTC AGCAGCACCG GCGGCAGGCT GCACCTGCAA


 


901
TGGCTGCCGC AGACCGTCCT GTCCTATTTC GACAGCTTCC GCACAAACAG


 


951
GCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1014; ORF 256-1>:










m256-1.pep




1
MILTPPDTPF FLRNGNADTI AAKFLQRPAP AYRRELLPDS TGKTKVAYDF


 


51
SDGISPDAPL VVLFHGLEGS SRSHYAVELM LAVRDRGWHG VVVHFRSCGG


 


101
IANTAPVFYH LGDTAEIAFT LDTFAARYRE IYAVGVSLGG NALAKYLGEQ


 


151
GKKALPQAAA VISAPVDAEA AGRRFDSGIT RLLYTRYFLR TLIPKAKSLQ


 


201
GFQTAFAAGC KTLGEFDDRF TAPLHGFADR HDYYRQTSCK PLLKHVAKPL


 


251
LLLNAVNDPF LPPEALPRAD EVSEAVTLFQ PAYGGHVGFV SSTGGRLHLQ


 


301
WLPQTVLSYF DSFRTNRR*






m256-1/g256-1 93.1% identity in 319 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1015>:










a256-1.seq




1
ATGATTTTGA CACCGCCGGA CACACCCTTT TTCCTCCGCA ACGGCAATGC


 


51
CGACACGATT GCCGCCAAAT TCCTGCAACG CTCCGCACCT GCATACCGCC


 


101
GCGAGCTGCT TCCCGACAGC ACGGGTAAAA CCAAAACCGC CTACGACTTT


 


151
TCAGACGGCA TTTCGCCCGA TGCGCCGCTG GTCGTGCTGT TTCACGGTTT


 


201
GGAGGGCGGC AGTGGCAGCC ATTACGCGGT CGAACTGATG CTCGCGGTAC


 


251
GCGATCGGGG TTGGAACGGC GTAGTCGTCC ATTTCCGCAG CTGCGGCGGC


 


301
GTAGCGAACA CCGCCCCGGT GTTCTACCAC TTGGGCGATA CCGCCGAAAT


 


351
TGCCTTTACT TTGGACACGC TCGCCGCGCG TTACCGTGAA ATATACGCCG


 


401
TCGGCGTATC GCTGGGCGGC AACGCGCTGG CAAAATATTT GGGCGAACAG


 


451
GGCGAAAACG CGCTGCCGCA AGCCGCCGCC GTCATCTCCG CACCCGTCGA


 


501
TGCAGAGGCG GCAGGCAACC GCTTCGACAG CGGCATCACA CGGCTGCTCT


 


551
ACACGCGCTA CTTCCTCCGC ACACTGATAC CCAAAGCACG GTCGCTCCAA


 


601
GGTTTTCAGA CGGCATTTGC CGCAGGGTGC AAAACACTGG GCGAGTTTGA


 


651
CGACCGTTTC ACCGCACCGC TGCACGGCTT TGCCGATCGG CACGACTACT


 


701
ACCGCCAAAC TTCCTGCAAA CCGCTGCTCA AACACGTTGC CAAACCGCTG


 


751
CTCCTGCTCA ATGCCGTCAA CGACCCCTTC CTGCCGCCCG AAGCGCTGCC


 


801
CCGCGCAGAC GAAGTGTCCG AAGCCGTTAC CCTGTTCCAG CCGACACACG


 


851
GTGGTCATGT CGGCTTTGTC GGCAGCACCG GCGGCAGGCT GCACCTGCAA


 


901
TGGTTGCCGC AGACCGTCCT GTCCTATTTC GACAGCTTCC GCACAAACAG


 


951
GCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1016; ORF 256-1.a>:










a256-1.pep




1
MILTPPDTPF FLRNGNADTI AAKFLQRSAP AYRRELLPDS TGKTKTAYDF


 


51
SDGISPDAPL VVLFHGLEGG SGSHYAVELM LAVRDRGWNG VVVHFRSCGG


 


101
VANTAPVFYH LGDTAEIAFT LDTLAARYRE IYAVGVSLGG NALAKYLGEQ


 


151
GENALPQAAA VISAPVDAEA AGNRFDSGIT RLLYTRYFLR TLIPKARSLQ


 


201
GFQTAFAAGC KTLGEFDDRF TAPLHGFADR HDYYRQTSCK PLLKHVAKPL


 


251
LLLNAVNDPF LPPEALPRAD EVSEAVTLFQ PTHGGHVGFV GSTGGRLHLQ


 


301
WLPQTVLSYF DSFRTNRR*






a256-1/m256-1 95.6% identity in 318 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1017>:










g257.seq




1
atgggcaggc atttcgggcg cagacgtttt ctgacggctg ccgccgttgc


 


51
tgtggccggt gcggcggttt cttttttgcc gaatcctttt gccgccggcg


 


101
gcgaaaaacg caacatggat aaaaaacgcg atgaaaatgt gtttttctgg


 


151
aaaggtgtcg cgctgggttc cggcgcggag ctgcgcctgt tcggcgtgga


 


201
cgacagacag gcggcggatt tggtcaataa ggttttggcg gaagtggcgc


 


251
gtttggaaaa aatgttcagc ctttaccgtg aagacagcct gatcagccgt


 


301
ctgaaccgcg acggttatct gacttcgcct ccggcggatt ttttggaact


 


351
gttgagcctg gccgcgatat tcacgcgctg a






This corresponds to the amino acid sequence <SEQ ID 1018; ORF 257.ng>:










g257.pep




1
MGRHFGRRRF LTAAAVAVAG AAVSFLPNPF AAGGEKRNMD KKRDENVFFW


 


51
KGVALGSGAE LRLFGVDDRQ AADLVNKVLA EVARLEKMFS LYREDSLISR


 


101
LNRDGYLTSP PADFLELLSL AAIFTR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1019>:










m257.seq




1
ATGGGCAGGC ATTTCGGGCG .CAGCGTTTT CTGACGGTTG CCGCCGTTGC


 


51
GGCGGGGaC. GCGGcGGTTT CTTTCCTGCC GAATCCTTTT GCCGCCGATG


 


101
ATGAAAAACG CAAcGGGGAT GAAAAACGCA ATGAAAATGT GTTTTTCTGG


 


151
AAAGGTGTCG CACTGGGTTC CGGTGCGGa. CTCCGTCTGT TCGGTGTGGA


 


201
CGACAGGCGT GCGGCGGATT TGGTCAACAA GGTTTTGGCG GAAGTGGCGC


 


251
GTTTGGAAAA ATTGTTCAGC CTTTACCGTG AAGACAGCCT GATCAGCCGC


 


301
CTGAACAGGG ACGGTTATCT GACTTCGCCG TCGGCGGATT TTTTGGAACT


 


351
GkTGAGCCTG GCCGCGATAT TCACGCkCTG A






This corresponds to the amino acid sequence <SEQ ID 1020; ORF 257>:










m257.pep




1
MGRHFGXQRF LTVAAVAAGX AAVSFLPNPF AADDEKRNGD EKRNENVFFW


 


51
KGVALGSGAX LRLFGVDDRR AADLVNKVLA EVARLEKLFS LYREDSLISR


 


101
LNRDGYLTSP SADFLELXSL AAIFTX*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 257 shows 88.0% identity over a 125 aa overlap with a predicted ORF (ORF 257.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1021>:










a257.seq




1
ATGGGCAGGC ATTTCGGGCG CAGGCGTTTT TTGACAGTTG CCGCCGTTGC


 


51
GGCGGCGGGC GCGGCGGTTT CTTTCCTGCC GAATCCTTTT GCCGCCGATG


 


101
ATGAAAAACG CAATAAAGAT GAAAAACGCA ATGAAAATGT GTTTTTCTGG


 


151
AAAGGTGTCG CACTGGGTTC CGGTGCGGAG CTCCGTCTGT TCGGTGTGGA


 


201
CGACAGGCGT GCGGCGGATT TGGTCAACAA GGTTTTGGCG GAAGTGGCGC


 


251
GTTTGGAAAA AATGTTCAGC CTTTACCGTG AAGACAGCCT GATCAGCCGT


 


301
CTGAACCGTG ACGGTTATTT GACTTCGCCG CCGGCGGATT TTTTGGAACT


 


351
GTTGAGCCTG GCCGTGATAT TCACGCGCTG A






This corresponds to the amino acid sequence <SEQ ID 1022; ORF 257.a>:










a257.pep




1
MGRHFGRRRF LTVAAVAAAG AAVSFLPNPF AADDEKRNKD EKRNENVFFW


 


51
KGVALGSGAE LRLFGVDDRR AADLVNKVLA EVARLEKMFS LYREDSLISR


 


101
LNRDGYLTSP PADFLELLSL AVIFTR*






m257/a257 92.0% identity in 125 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1023>:










g258.seq




1
atgcgccgct tcctaccgat cgcagccata tgcgccgtcg tcctgctgta


 


51
cggattgacg gcggcgaccg gcagcaccag ttcgctggcg gattatttct


 


101
ggtggatagt ctcgttcagc gcaatgctgc tgctggtgtt gtccgccgtt


 


151
ttggcacgtt atgtcatatt gctgttgaaa gacaggcgca acggcgtgtt


 


201
cggttcgcag attgccaaac gcctttccgg gatgttcacg ctggtcgccg


 


251
tactgcccgg cttgttcctg ttcggcattt ccgcgcagtt tatcaacggc


 


301
acgattaatt cgtggttcgg caacgacacc cacgaagccc tcgaacgcag


 


351
ccttaatttg agcaagtccg cactggattt ggcggcagac aatgccgtca


 


401
gcaacgccgt tcccgtacag atagacctca tcggcaccgc ctccctgtcg


 


451
ggcaatatgg gcagtgtgct ggaacactac gccggcagcg gttttgccca


 


501
gcttgccctg tacaatgccg caagcgggaa aatcgaaaaa agcatcaatc


 


551
cgcaccaatt cgaccagccg cttcccgaca aagaacattg ggaacagatt


 


601
cagcagaccg gttcggttcg gagtttggaa agcataggcg gcgtattgta


 


651
cgcgcaggga tggttgtcgg caggtacgca caacgggcgc gattacgcgc


 


701
tgttcttccg ccagccgatt cccgaaaatg tggcacagga tgccgttctg


 


751
attgaaaagg cgcgggcgaa atatgccgaa ttgagttaca gcaaaaaagg


 


801
tttgcagacc ttttttctgg taaccctgct gattgcctcg ctgctgtcga


 


851
tttttcttgc gctggtaatg gcactgtatt ttgcccgccg tttcgtcgaa


 


901
cccattctgt cgcttgccga gggcgcaaag gcggtggcgc agggtgattt


 


951
cagccagacg cgccccgtat tgcgcaacga cgagttcgga cgtttgacca


 


1001
agctgttcaa ccatatgacc gagcagcttt ccatcgccaa agaagcagac


 


1051
gaacgcaacc gccggcgcga ggaagccgcc cgtcactacc tcgagtgcgt


 


1101
gttggatggg ttgactaccg gtgtggtggt ctcntacccc ctctcttgtt


 


1151
gccgtaccgc ggtgttttcc acttgtcatt cctcccctct ttcttatttc


 


1201
taa






This corresponds to the amino acid sequence <SEQ ID 1024; ORF 258.ng>:










g258.pep




1
MRRFLPIAAI CAVVLLYGLT AATGSTSSLA DYFWWIVSFS AMLLLVLSAV


 


51
LARYVILLLK DRRNGVFGSQ IAKRLSGMFT LVAVLPGLFL FGISAQFING


 


101
TINSWFGNDT HEALERSLNL SKSALDLAAD NAVSNAVPVQ IDLIGTASLS


 


151
GNMGSVLEHY AGSGFAQLAL YNAASGKIEK SINPHQFDQP LPDKEHWEQI


 


201
QQTGSVRSLE SIGGVLYAQG WLSAGTHNGR DYALFFRQPI PENVAQDAVL


 


251
IEKARAKYAE LSYSKKGLQT FFLVTLLIAS LLSIFLALVM ALYFARRFVE


 


301
PILSLAEGAK AVAQGDFSQT RPVLRNDEFG RLTKLFNHMT EQLSIAKEAD


 


351
ERNRRREEAA RHYLECVLDG LTTGVVVSYP LSCCRTAVFS TCHSSPLSYF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1025>:










m258.seq




1
ATGCGCCGTT TTCTACCGAT CGCAGCCATA TGCGCCGTCG TCCTGTTGTA


 


51
CGGACTGACG GCGGCAACCG GCAGCACCAG TTCGCTGGCG GATTATTTCT


 


101
GGTGGATTGT TGCGTTCAGC GCAATGCTGC TGCTGGTGTT GTCCGCCGTT


 


151
TTGGCACGTT ATGTCATATT GCTGTTGAAA GACAGGCGCG ACGGCGTATT


 


201
CGGTTCGCAG ATTGCCAAAC GCCTTTCTGG GATGTTTACG CTGGTTGCCG


 


251
TACTGCCCGG CGTGTTTCTG TTCGGCGTTT CCGCACAGTT CATCAACGGC


 


301
ACGATTAATT CGTGGTTCGG CAACGATACC CACGAGGCGC TTGAACGCAG


 


351
CCTCAATTTG AGCAAGTCCG CATTGAATTT GGCGGCAGAC AACGCCCTCG


 


401
GCAACGCCGT CCCCGTGCAG ATAGACCTCA TCGGCGCGGC TTCCCTGCCC


 


451
GGGGATATGG GCAGGGTGCT GGAACATTAC GCCGGCAGCG GTTTTGCCCA


 


501
GCTTGCCCTG TACAATGCCG CAAGCGGCAA AATCGAAAAA AGCATCAACC


 


551
CGCACAAGCT CGATCAGCCG TTTCCAGGTA AGGCGCGTTG GGAAAAAATC


 


601
CAACGGGCGG GTTCGGTCAG GGATTTGGAA AGCATAGGCG GCGTATTGTA


 


651
CGCGCAGGGC TGGCTGTCGG CGGGTACGCA CAACGGGCGC GATTACGCCT


 


701
TGTTTTTCCG TCAGCCGGTT CCCAAAGGCG TGGCAGAGGA TGCCGTCTTA


 


751
ATCGAAAAGG CAAGGGCGAA ATATGCTGAG TTGAGTTACA GCAAAAAAGG


 


801
TTTGCAGACC TTTTTCCTGG CAACCCTGCT GATTGCCTCG CTGCTGTCGA


 


851
TTTTTCTTGC ACTGGTCATG GCACTGTATT TCGCCCGCCG TTTCGTCGAA


 


901
CCCGTCCTAT CGCTTGCCGA GGGGGCGAAG GCGGTGGCGC AAGGCGATTT


 


951
CAGCCAGACG CGCCCCGTGT TGCGCAACGA CGAGTTCGGA CGCTTGACCA


 


1001
AGTTGTTCAA CCACATGACC GAGCAGCTTT CCATCGCCAA AGAAGCAGAC


 


1051
GAGCGCAACC GCCGGCGCGA GGAAGCCGCC AGGCATTATC TTGAATGCGT


 


1101
GTTGGAGGGG CTGACCACGG GCGTGGTGGT GTTTGACGAA CAAGGCTGTC


 


1151
TGAAAACsTT CAACAAAGCG GCGGAACAGA TTyTGGGGAT GCCGCTTACC


 


1201
CCCcTGTGGG GCAGCAGCCG GCACGGTTGG CACGGCGTTT CGGCGCAGCA


 


1251
GTCCCTGCTT GCCGAAGTGT TTGCCGCCAT CGGCGCGGCG GCAGGTACGG


 


1301
ACAAACCGGT CCATGTGAAA TATGCCGCGC CGGACGATGC CAAAATCCTG


 


1351
CTGGGCAAGG CAACCGTCCT GCCCGAAGAC AACGGCAACg GCGTGGTAAT


 


1401
GGTGATTGAC GACATCACCG TTTTGATACA CGCGCAAAAA GAAGCCGCGT


 


1451
GGGGCGAAgT GGCGaAgCGG CTGGCACACG AAATCCGCAA TCCGCTCACG


 


1501
CCCATCCAGC TTTCCGCCGA ACgGsTGGCG TkGAAATTGG GCGGGAAGCT


 


1551
GGATGAGCAG GATGCGCAAA TCCTGACGCG TTCGACCGAC ACCATCGTCA


 


1601
AACAGGTGGC GGCATTGAAG GAAATGGTCG AAGCATTCCG CAATTATGCG


 


1651
CGTTCCCCTT CGCTCAAATT GGAAAATCAG GATTTGAACG CCTTAATCGG


 


1701
CGATGTGTTG GCATTGTATG AAGCCGGTCC GTGCCGGTTT GCGGCGGACT


 


1751
TGCCGGCGAA CCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1026; ORF 258>:










m258.pep




1
MRRFLPIAAI CAVVLLYGLT AATGSTSSLA DYFWWIVAFS AMLLLVLSAV


 


51
LARYVILLLK DRRDGVFGSQ IAKRLSGMFT LVAVLPGVFL FGVSAQFING


 


101
TINSWFGNDT HEALERSLNL SKSALNLAAD NALGNAVPVQ IDLIGAASLP


 


151
GDMGRVLEHY AGSGFAQLAL YNAASGKIEK SINPHKLDQP FPGKARWEKI


 


201
QRAGSVRDLE SIGGVLYAQG WLSAGTHNGR DYALFFRQPV PKGVAEDAVL


 


251
IEKARAKYAE LSYSKKGLQT FFLATLLIAS LLSIFLALVM ALYFARRFVE


 


301
PVLSLAEGAK AVAQGDFSQT RPVLRNDEFG RLTKLFNHMT EQLSIAKEAD


 


351
ERNRRREEAA RHYLECVLEG LTTGVVVFDE QGCLKTFNKA AEQILGMPLT


 


401
PLWGSSRHGW HGVSAQQSLL AEVFAAIGAA AGTDKPVHVK YAAPDDAKIL


 


451
LGKATVLPED NGNGVVMVID DITVLIHAQK EAAWGEVAKR LAHEIRNPLT


 


501
PIQLSAERXA XKLGGKLDEQ DAQILTRSTD TIVKQVAALK EMVEAFRNYA


 


551
RSPSLKLENQ DLNALIGDVL ALYEAGPCRF AADLPANR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 258 shows 90.9% identity over a 386 aa overlap with a predicted ORF (ORF 258.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1027>:










a258.seq




1
ATGCGCCGTT TTCTACCGAT CGCAGCCATA TGCGCCGTCG TCCTGTTGTA


 


51
CGGACTGACG GCGGCAACCG GCAGCACCAG TTCGCTGGCG GATTATTTCT


 


101
GGTGGATTGT TGCGTTCAGC GCAATGCTGC TGCTGGTGTT GTCCGCCGTT


 


151
TTGGCACGTT ATGTCATATT GCTGTTGAAA GACAGGCGCG ACGGCGTATT


 


201
CGGTTCGCAG ATTGCCAAAC GCCTTTCCGG GATGTTTACG CTGGTTGCCG


 


251
TACTGCCCGG CGTGTTTCTG TTCGGCGTTT CCGCACAGTT TATCAACGGC


 


301
ACGATTAATT CGTGGTTCGG CAACGATACC CACGAGGCGC TTGAACGCAG


 


351
CCTCAATTTG AGCAAGTCCG CATTGAATCT GGCGGCAGAC AACGCCCTTG


 


401
GCAACGCCAT CCCCGTGCAG ATAGACCTCA TCGGCGCGGC TTCCCTGCCC


 


451
GGGGATATGG GCAGGGTGCT GGAACATTAC GCCGGCAGCG GTTTTGCCCA


 


501
GCTTGCCCTG TACAATGCCG CAAGCGGCAA AATCGAAAAA AGCATCAACC


 


551
CGCACAAGCT CGATCAGCCG TTTCCAGGTA AGGCGCGTTG GGAAAAAATC


 


601
CAACAGGCGG GTTCGGTCAG GGATTTGGAA AGCATAGGCG GCGTATTGTA


 


651
CGCGCAGGGC TGGCTGTCGG CAGGTACGCA CAACGGGCGC GATTACGCCT


 


701
TGTTTTTCCG TCAGCCGGTT CCCAAAGGCG TGGCAGAGGA TGCCGTCTTA


 


751
ATCGAAAAGG CAAGGGCGAA ATATGCTGAG TTGAGTTACA GCAAAAAAGG


 


801
TTTGCAGACC TTTTTCCTGG CAACCCTGCT GATTGCCTCG CTGCTGTCGA


 


851
TTTTTCTTGC ACTGGTCATG GCACTGTATT TCGCCCGCCG TTTCGTCGAA


 


901
CCCGTCCTAT CGCTTGCCGA GGGGGCGAAG GCGGTGGCGC AAGGCGATTT


 


951
CAGCCAGACG CGCCCCGTGT TGCGCAACGA CGAGTTCGGA CGCTTGACCA


 


1001
AGTTGTTCAA CCACATGACC GAGCAGCTTT CCATCGCCAA AGAAGCAGAC


 


1051
GAGCGCAACC GCCGGCGCGA GGAAGCCGCC AGACATTATC TCGAATGCGT


 


1101
GTTGGAGGGG CTGACCACGG GCGTGGTGGT GTTTGACGAA CAAGGCTGTC


 


1151
TGAAAACCTT CAACAAAGCG GCGGAACAGA TTTTGGGGAT GCCGCTTACC


 


1201
CCCCTGTGGG GCAGCAGCCG GCACGGTTGG CACGGCGTTT CGGCGCAGCA


 


1251
GTCCCTGCTT GCCGAAGTGT TTGCCGCCAT CGGCGCGGCG GCAGGTACGG


 


1301
ACAAACCGGT CCATGTGAAA TATGCCGCGC CGGACGATGC CAAAATCCTG


 


1351
CTGGGCAAGG CAACCGTCCT GCCCGAAGAC AACGGCAACG GCGTGGTAAT


 


1401
GGTGATTGAC GACATCACCG TTTTGATACA CGCGCAAAAA GAAGCCGCGT


 


1451
GGGGCGAAGT GGCAAAACGG CTGGCACACG AAATCCGCAA TCCGCTCACG


 


1501
CCCATCCAGC TTTCTGCCGA ACGGCTGGCG TGGAAATTGG GCGGGAAGCT


 


1551
GGACGAGCAG GACGCGCAAA TCCTGACACG TTCGACCGAC ACCATCATCA


 


1601
AACAAGTGGC GGCATTAAAA GAAATGGTCG AGGCATTCCG CAATTACGCG


 


1651
CGTTCCCCTT CGCTCAAATT GGAAAATCAG GATTTGAACG CCTTAATCGG


 


1701
CGATGTGTTG GCATTGTACG AAGCTGGTCC GTGCCGGTTT GCGGCGGAAC


 


1751
TTGCCGGCGA ACCGCTGATG ATGGCGGCGG ATACGACCGC CATGCGGCAG


 


1801
GTGCTGCACA ATATTTTCAA AAATGCCGCC GAAGCGGCGG AAGAAGCCGA


 


1851
TGTGCCCGAA GTCAGGGTAA AATCGGAAGC GGGGCAGGAC GGACGGATTG


 


1901
TCCTGACAGT TTGCGACAAC GGCAAGGGGT TCGGCAGGGA AATGCTGCAC


 


1951
AATGCCTTCG AGCCGTATGT AACGGACAAA CCGGCTGGAA CGGGATTGGG


 


2001
ACTGCCCGTG GTGAAAAAAA TCATTGAAGA ACACGGCGGC CGCATCAGCC


 


2051
TGAGCAATCA GGATGCGGGC GGCGCGTGTG TCAGAATCAT CTTGCCAAAA


 


2101
ACGGTAGAAA CTTATGCGTA G






This corresponds to the amino acid sequence <SEQ ID 1028; ORF 258.a>:










a258.pep




1
MRRFLPIAAI CAVVLLYGLT AATGSTSSLA DYFWWIVAFS AMLLLVLSAV


 


51
LARYVILLLK DRRDGVFGSQ IAKRLSGMFT LVAVLPGVFL FGVSAQFING


 


101
TINSWFGNDT HEALERSLNL SKSALNLAAD NALGNAIPVQ IDLIGAASLP


 


151
GDMGRVLEHY AGSGFAQLAL YNAASGKIEK SINPHKLDQP FPGKARWEKI


 


201
QQAGSVRDLE SIGGVLYAQG WLSAGTHNGR DYALFFRQPV PKGVAEDAVL


 


251
IEKARAKYAE LSYSKKGLQT FFLATLLIAS LLSIFLALVM ALYFARRFVE


 


301
PVLSLAEGAK AVAQGDFSQT RPVLRNDEFG RLTKLFNHMT EQLSIAKEAD


 


351
ERNRRREEAA RHYLECVLEG LTTGVVVFDE QGCLKTFNKA AEQILGMPLT


 


401
PLWGSSRHGW HGVSAQQSLL AEVFAAIGAA AGTDKPVHVK YAAPDDAKIL


 


451
LGKATVLPED NGNGVVMVID DITVLIHAQK EAAWGEVAKR LAHEIRNPLT


 


501
PIQLSAERLA WKLGGKLDEQ DAQILTRSTD TIIKQVAALK EMVEAFRNYA


 


551
RSPSLKLENQ DLNALIGDVL ALYEAGPCRF AAELAGEPLM MAADTTAMRQ


 


601
VLHNIFKNAA EAAEEADVPE VRVKSEAGQD GRIVLTVCDN GKGFGREMLH


 


651
NAFEPYVTDK PAGTGLGLPV VKKIIEEHGG RISLSNQDAG GACVRIILPK


 


701
TVETYA*






m258/a258 99.0% identity in 584 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1029>:










g259.seq




1
atgatgatgc acgcttctgt ccaaagtcgt ttcgcaccga tactttatgt


 


51
tttgattttc tttgccggtt ttttgaccgc gcaaatctgg ttcaatcaga


 


101
aagcctatac tgaagagctg cctccgcttc tgtccgcatt gtccgccgtc


 


151
gcgctggtgt ggctggcgtg ggcgttcgtg tcggtgcgtt caaaggctaa


 


201
ggcagaaaag ttctaccgcg aaaaaatgat acagaacgaa agcatacacc


 


251
ccgtcctgca cgcttctttg caacacttgg aacacaagcc gcaaatgctc


 


301
gccctgctgg tcaaaaacca cggcaaaggc atggcggaac aggtcaggtt


 


351
caaggcggaa gtgctgcccg acgacgaaga cgcgcgcacg attgccgccg


 


401
agttggcaaa aatggatatg ttcgcattgg ggacggacgc ggtcgcctcg


 


451
ggcgaaacct atgggcgcgt gttcgccgat attttcgagt tgtcggcggc


 


501
tttggaaagg cgcgcgttca aagggatact gaaactgacg gcggaatata


 


551
aaaaacatct tcggcgatgc ctgccgttcg gaaacggcgt tggatttggg


 


601
cgcgctcaat caggcgttga gggaaatctc gaaaacgccg gaaaagccta


 


651
a






This corresponds to the amino acid sequence <SEQ ID 1030; ORF 259.ng>:










g259.pep




1
MMMHASVQSR FAPILYVLIF FAGFLTAQIW FNQKAYTEEL PPLLSALSAV


 


51
ALVWLAWAFV SVRSKAKAEK FYREKMIQNE SIHPVLHASL QHLEHKPQML


 


101
ALLVKNHGKG MAEQVRFKAE VLPDDEDART IAAELAKMDM FALGTDAVAS


 


151
GETYGRVFAD IFELSAALER RAFKGILKLT AEYKKHLRRC LPFGNGVGFG


 


201
RAQSGVEGNL ENAGKA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1031>:









m259.seq (partial)










1
ATGATGATGC ACGCTTCTGT CCAAAGCCGT TTCGCACCGA TACTTTATGT



 


51
TTTGATTTTC TTTGCCGGTT TTTTGACCGC GCAAATCTGG TTCAATCAGA


 


101
AAGCCTATAC TGAAGAGCTG CCTCCGCTTC TGTCCGCATT GTCCGCCGTC


 


151
GCGCTGGTGT GGCTGGCGTG GGCGTTCGTG TCGGCGCGTT CAAAGGCCAA


 


201
GGCGGAAAAG TTCTACCGCG AAAAAATGAT ACAGAACGAA AGCATACACC


 


251
CCGTCsTGCA CGCCTCTTTG CAACACTTGG AACACAAGCC GCAAATACTC


 


301
GCCCTGCTGG TCAAAAACCA CGGCAAAGGG ATGGCGGAAC AGGTCAGGTT


 


351
CAAGGCGGAA GTGCTGCCCG ACGACGAAGA CGCGCGCACG ATTGCCGCCG


 


401
AGTTGGCAAA AATGGATATG TTCGCATTGG GGACkGACGC GGTCGCCTCG


 


451
GGCGAAACCT ATGGACGCGT GTTCGCCGAT ATTTTCGAGT TGTCGGmGGC


 


501
TTTGGAAGGG CGCGCGTTCA AAGGAATGTT GAAACTGACG GCGGAATATA


 


551
AA.AACATCT TCGGmGATGC CTGCCGTTCG GAAACGGCGT TGGAGTTGGG


 


601
CGCACTCAAT CAGGCGTTGC AGGAGATTTC AAAAACATCC GG..






This corresponds to the amino acid sequence <SEQ ID 1032; ORF 259>:









m259.pep (partial)










1
MMMHASVQSR FAPILYVLIF FAGFLTAQIW FNQKAYTEEL PPLLSALSAV



 


51
ALVWLAWAFV SARSKAKAEK FYREKMIQNE SIHPVXHASL QHLEHKPQIL


 


101
ALLVKNHGKG MAEQVRFKAE VLPDDEDART IAAELAKMDM FALGTDAVAS


 


151
GETYGRVFAD IFELSXALEG RAFKGMLKLT AEYKXHLRRC LPFGNGVGVG


 


201
RTQSGVAGDF KNIR..






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 259 shows 94.3% identity over a 212 aa overlap with a predicted ORF (ORF 259.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1033>:









a259.seq (partial)










1
ATGATGATGC ACGCTTCTGT CCAAAGCCGT TTCGCACCGA TACTTTATGT



 


51
TTTGATTTTC TTTGCCGGTT TTTTGACCGC GCAAATCTGG TTCAATCAGA


 


101
AAGCCTATAC TGAAGAGCTG CCTCCGCTTC TGTCCGCATT GTCCGCCGTC


 


151
GCGCTGGTGT GGCTGGCGTG GGCGTTCGTG TCGGCGCGTT CAAAGGCTAA


 


201
GGCGGAAAAG TTCTACCGCG AAAAAATGAT ACAGAACGAA AGCATACACC


 


251
CCGTCCTGCA CGCTTCTTTG CAACACTTGG AACACAAGCC GCAAATGCTC


 


301
GCCCTGCTGG TCAAAAACCA CGGCAAAGGG ATGGCGGAAC AGGTCAGGTT


 


351
CAAGGCGGAA GTGCTGCCCG ACGACGAAGA CGCGCGCACG ATTGCCGCCG


 


401
AGTTGGCAAA AATGGATATG TTTGCATTGG GGACGGACGC GGTCGCCTCG


 


451
GGCGAAACCT ATGGACGCGT GTTCGCCGAT ATTTTCGAGT TGTCGGCGGC


 


501
TTTGGAAGGG CGCGCGTTCA AAGGAATGTT GAAACTGACG GCGGAATATA


 


551
AAAA.CATCT TCGGCGATGC CTGCCGTTCG GAAACGGCGT TGGAGTTGGG


 


601
CGCGCTCAAT CAGGCGTTGC AGGAGATTTC AAAAACATCG GAAAAGTCCA


 


651
A






This corresponds to the amino acid sequence <SEQ ID 1034; ORF 259.a>:









a259.pep (partial)










1
MMMHASVQSR FAPILYVLIF FAGFLTAQIW FNQKAYTEEL PPLLSALSAV



 


51
ALVWLAWAFV SARSKAKAEK FYREKMIQNE SIHPVLHASL QHLEHKPQML


 


101
ALLVKNHGKG MAEQVRFKAE VLPDDEDART IAAELAKMDM FALGTDAVAS


 


151
GETYGRVFAD IFELSAALEG RAFKGMLKLT AEYKXHLRRC LPFGNGVGVG


 


201
RAQSGVAGDF KNIGKVQ






m259/a259 98.1% identity in 213 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1035>:










g259-1.seq




1
ATGATGATGC ACGCTTCTGT CCAAAGTCGT TTCGCACCGA TACTTTATGT


 


51
TTTGATTTTC TTTGCCGGTT TTTTGACCGC GCAAATCTGG TTCAATCAGA


 


101
AAGCCTATAC TGAAGAGCTG CCTCCGCTTC TGTCCGCATT GTCCGCCGTC


 


151
GCGCTGGTGT GGCTGGCGTG GGCGTTCGTG TCGGTGCGTT CAAAGGCTAA


 


201
GGCAGAAAAG TTCTACCGCG AAAAAATGAT ACAGAACGAA AGCATACACC


 


251
CCGTCCTGCA CGCTTCTTTG CAACACTTGG AACACAAGCC GCAAATGCTC


 


301
GCCCTGCTGG TCAAAAACCA CGGCAAAGGC ATGGCGGAAC AGGTCAGGTT


 


351
CAAGGCGGAA GTGCTGCCCG ACGACGAAGA CGCGCGCACG ATTGCCGCCG


 


401
AGTTGGCAAA AATGGATATG TTCGCATTGG GGACGGACGC GGTCGCCTCG


 


451
GGCGAAACCT ATGGGCGCGT GTTCGCCGAT ATTTTCGAGT TGTCGGCGGC


 


501
TTTGGAA






This corresponds to the amino acid sequence <SEQ ID 1036; ORF 259-1.ng>:










g259-1.pep




1
MMMHASVQSR FAPILYVLIF FAGFLTAQIW FNQKAYTEEL PPLLSALSAV


 


51
ALVWLAWAFV SVRSKAKAEK FYREKMIQNE SIHPVLHASL QHLEHKPQML


 


101
ALLVKNHGKG MAEQVRFKAE VLPDDEDART IAAELAKMDM FALGTDAVAS


 


151
GETYGRVFAD IFELSAALE






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1037>:










m259-1.seq




1
ATGATGATGC ACGCTTCTGT CCAAAGCCGT TTCGCACCGA TACTTTATGT


 


51
TTTGATTTTC TTTGCCGGTT TTTTGACCGC GCAAATCTGG TTCAATCAGA


 


101
AAGCCTATAC TGAAGAGCTG CCTCCGCTTC TGTCCGCATT GTCCGCCGTC


 


151
GCGCTGGTGT GGCTGGCGTG GGCGTTCGTG TCGGCGCGTT CAAAGGCCAA


 


201
GGCGGAAAAG TTCTACCGCG AAAAAATGAT ACAGAACGAA AGCATACACC


 


251
CCGTCCTGCA CGCCTCTTTG CAACACTTGG AACACAAGCC GCAAATACTC


 


301
GCCCTGCTGG TCAAAAACCA CGGCAAAGGG ATGGCGGAAC AGGTCAGGTT


 


351
CAAGGCGGAA GTGCTGCCCG ACGACGAAGA CGCGCGCACG ATTGCCGCCG


 


401
AGTTGGCAAA AATGGATATG TTCGCATTGG GGACGGACGC GGTCGCCTCG


 


451
GGCGAAACCT ATGGACGCGT GTTCGCCGAT ATTTTCGAGT TGTCGGCGGC


 


501
TTTGGAAGGG CGCGCGTTCA AAGGAATGTT GAAACTGACG GCGGAATATA


 


551
AAAACATCTT CGGCGATGCC TGCCGTTCGG AAACGGCGTT GGAGTTGGGC


 


601
GCACTCAATC AGGCGTTGCA GGAGATTTCA AAAACATCGG AAAAGTCCAA


 


651
ACGGATATTT TATTGA






This corresponds to the amino acid sequence <SEQ ID 1038; ORF 259-1>:










m259-1.pep




1
MMMHASVQSR FAPILYVLIF FAGFLTAQIW FNQKAYTEEL PPLLSALSAV


 


51
ALVWLAWAFV SARSKAKAEK FYREKMIQNE SIHPVLHASL QHLEHKPQIL


 


101
ALLVKNHGKG MAEQVRFKAE VLPDDEDART IAAELAKMDM FALGTDAVAS


 


151
GETYGRVFAD IFELSAALEG RAFKGMLKLT AEYKNIFGDA CRSETALELG


 


201
ALNQALQEIS KTSEKSKRIF Y*






g259-1/m259-1 98.8% identity in 169 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1039>:










a259-1.seq




1
ATGATGATGC ACGCTTCTGT CCAAAGCCGT TTCGCACCGA TACTTTATGT


 


51
TTTGATTTTC TTTGCCGGTT TTTTGACCGC GCAAATCTGG TTCAATCAGA


 


101
AAGCCTATAC TGAAGAGCTG CCTCCGCTTC TGTCCGCATT GTCCGCCGTC


 


151
GCGCTGGTGT GGCTGGCGTG GGCGTTCGTG TCGGCGCGTT CAAAGGCTAA


 


201
GGCGGAAAAG TTCTACCGCG AAAAAATGAT ACAGAACGAA AGCATACACC


 


251
CCGTCCTGCA CGCTTCTTTG CAACACTTGG AACACAAGCC GCAAATGCTC


 


301
GCCCTGCTGG TCAAAAACCA CGGCAAAGGG ATGGCGGAAC AGGTCAGGTT


 


351
CAAGGCGGAA GTGCTGCCCG ACGACGAAGA CGCGCGCACG ATTGCCGCCG


 


401
AGTTGGCAAA AATGGATATG TTTGCATTGG GGACGGACGC GGTCGCCTCG


 


451
GGCGAAACCT ATGGACGCGT GTTCGCCGAT ATTTTCGAGT TGTCGGCGGC


 


501
TTTGGAAGGG CGCGCGTTCA AAGGAATGTT GAAACTGACG GCGGAATATA


 


551
AAAACATCTT CGGCGATGCC TGCCGTTCGG AAACGGCGTT GGAGTTGGGC


 


601
GCGCTCAATC AGGCGTTGCA GGAGATTTCA AAAACATCGG AAAAGTCCAA


 


651
ACGGATATTT TATTGA






This corresponds to the amino acid sequence <SEQ ID 1040; ORF 259-1.a>:










a259-1.pep




1
MMMHASVQSR FAPILYVLIF FAGFLTAQIW FNQKAYTEEL PPLLSALSAV


 


51
ALVWLAWAFV SARSKAKAEK FYREKMIQNE SIHPVLHASL QHLEHKPQML


 


101
ALLVKNHGKG MAEQVRFKAE VLPDDEDART IAAELAKMDM FALGTDAVAS


 


151
GETYGRVFAD IFELSAALEG RAFKGMLKLT AEYKNIFGDA CRSETALELG


 


201
ALNQALQEIS KTSEKSKRIF Y*






a259-1/m259-1 99.5% identity in 221 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1041>:










g260.seq




1
atgggtgcgg gtgtagtatt cgttgtcttt cagccgttct tcagcctgtt


 


51
tcgagcgttg ttcgagggcg gagtcggtat agtcgaggga gcgcacgatg


 


101
ccgctgaatg cgacttcttg tccgaggaat ttacccgtat ccggatcggt


 


151
gatgttttta ttgattcggt aggtcagata acggcccggt tctttcaggc


 


201
ctttggtgta aaccctggcg cctttggtgt acagcagcct gccttccggg


 


251
cccgagagca ggcgcggcgc ggcagcggtt tctttgcggg aaacgatttg


 


301
cgggtgctgc ataaagacgc ggtagaagtt gacatcgatg gcgggaatac


 


351
cgtatccgga cacttcctta tccggactga ttttgacgac ggggatgccg


 


401
tctgtctgtt ccaagccgag gcgcggttcg ccgccaacgt agcgcaacac


 


451
caatacctgg cccggataaa tcaggtcggg attgtggatt tgatcccggt


 


501
tcgcgcccca caggggggga ccattgccac gggctgtaca ggtatttgcc


 


551
cgaaataccc cacagggtgt cgccctgttt ga






This corresponds to the amino acid sequence <SEQ ID 1042; ORF 260.ng>:










g260.pep




1
MGAGVVFVVF QPFFSLFRAL FEGGVGIVEG AHDAAECDFL SEEFTRIRIG


 


51
DVFIDSVGQI TARFFQAFGV NPGAFGVQQP AFRAREQARR GSGFFAGNDL


 


101
RVLHKDAVEV DIDGGNTVSG HFLIRTDFDD GDAVCLFQAE ARFAANVAQH


 


151
QYLARINQVG IVDLIPVRAP QGGTIATGCT GICPKYPTGC RPV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1043>:










m260.seq




1
ATGGGTGCGG GTATGGTATT CGTTGTCTTT CGGCCGTTCT CCAGCCTGTT



 


51
TCGAGCGTTG TTCGAGGACA GAGTCGGTAT AGTCGAGGGA GCGCACGATG


 


101
CCGCTGAATG CGACTTCCTG CCCGAGGAAT TTACCCGTAT CCGGATCGGT


 


151
GATGTTTTTA TTGATTCGGT AGGTCAGGTA GCGGCCCGGC TCTTTCAGGC


 


201
CTTTGGTGTA AACCCTGGTG CCTTTGGTGT ACAGCAGCCT GCCTTCCGGG


 


251
CCCGAGwrCA sGCGCGGyGC GGCAGCGGTT TCTTTGCGGG AAACGATTTG


 


301
CGGATGCCGC ATAAAGATGC GGTAGAAGTT GACATCGATG GCGGGAATAC


 


351
CGTATCCGGA CACTTCCTTA TCCGGACTCA TTTTGACGAC GGGGATGCCG


 


401
TCTGTCTGTT CCAAGCCGAG GCGCGGTTCG CCGTCAACGT GGCGCAACAC


 


451
CAATACCTGG TCCGGATAAA TCAGGTCGGG ATTGTGGATT TGATCCCGGT


 


501
TCGCGTyCCA CAG






This corresponds to the amino acid sequence <SEQ ID 1044; ORF 260>:










m260.pep




1
MGAGMVFVVF RPFSSLFRAL FEDRVGIVEG AHDAAECDFL PEEFTRIRIG



 


51
DVFIDSVGQV AARLFQAFGV NPGAFGVQQP AFRARXXARX GSGFFAGNDL


 


101
RMPHKDAVEV DIDGGNTVSG HFLIRTHFDD GDAVCLFQAE ARFAVNVAQH


 


151
QYLVRINQVG IVDLIPVRVP Q






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 260 shows 89.5% identity over a 171 aa overlap with a predicted ORF (ORF 260.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1045>:










a260.seq




1
ATGGGTGCGG GTATGGTATT CGTTGTCTTT CGGCCGTTCT CCAGCCTGTT



 


51
TCGAGCGTTG TTCGAGGACA GAGTCGGTAT AGTCGAGGGA GCGCACGATG


 


101
CCGCTGAATG CGACTTCCTG CCCGAGGAAT TTACCCGTAT CCGGATCGGT


 


151
GATGTTTTTA TTGATTCGGT AGGTCAGGTA GCGGCCCGGC TCTTTCAGGC


 


201
CTTTGGTGTA AACCCTGGTG CCTTTGGTGT ACAGCAGCCT GCCTTCCGGG


 


251
CCCGAGAGCA GGCGCGGCGC GGCAGCGGTT TCTTTGCGGG AAACGATTTG


 


301
CGGGTGCCGC ATAAAGATGC GGTAGAAGTT GACATCGATG GCGGGAATAC


 


351
CGTATCCGGA CACTTCCTTA TCCGGACTCA TTTTGACGAC GGGGATGCCG


 


401
TCTGTCTGTT CCAAGCCGAG GCGCGGTTCG CCGTCAACGT GGCGCAACAC


 


451
CAATACCTGG TCCAGATAAA TCAGGTCGGG ATTGTGGATT TGATCCCGGT


 


501
TCGCGTCCCA CAGGCGGCC. CCATTGCCAC GGGCTGTACA GGTATTTGCC


 


551
CGAAATGCCC CACAGGGTGT CGCCCTGTTT GA






This corresponds to the amino acid sequence <SEQ ID 1046; ORF 260.a>:










a260.pep




1
MGAGMVFVVF RPFSSLFRAL FEDRVGIVEG AHDAAECDFL PEEFTRIRIG



 


51
DVFIDSVGQV AARLFQAFGV NPGAFGVQQP AFRAREQARR GSGFFAGNDL


 


101
RVPHKDAVEV DIDGGNTVSG HFLIRTHFDD GDAVCLFQAE ARFAVNVAQH


 


151
QYLVQINQVG IVDLIPVRVP QAAXIATGCT GICPKCPTGC RPV*






m260/a260 97.1% identity in 171 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1047>:










g261.seq




1
atggagcttg ggcatatcgt attccttgtg ctttgcgcgc gttcagacgg



 


51
cctttttact ttccagacat tccgccagcc cgcgttcgcg caagatacag


 


101
ctcgggcatt cgcggcagcc gccgacgata cccttgtagc aggtgtgggt


 


151
ctgttcgcgg atgtagtcca acacgcccat ttcgtccgcc aacgcccacg


 


201
tttgcgcctt ggtcaggtac atcagcggcg tgtggatttg aaaatcgtag


 


251
tccatcgcca gattaagggt aacgttcatg gatttgacga acacgccgcg


 


301
gcagtcggga tagcccgaaa aatcggtttc gcacacgccc gcgatgatgt


 


351
gccggatacc ctgccctttg gcaaaaatgg cggcgtaaag caggaaaagc


 


401
gcgttacgcc cgtccacaaa ggtattggga acgccgttgt cggcggtttc


 


451
gatggcggcg gtttcgatgg cggcggtttc gtccatcagg gcgttgtgcg


 


501
taatctgccg catcaggctc aaatcgagta cggtttgact gacacccaaa


 


551
tcctgcgcga tccactctgc gcgttccagc tcgacggcat ggcgttgccc


 


601
gtatcggaag gtgatggctt ggacgttttc gcgcccgtag gtttggattg


 


651
cctgaatcag gcaggtggtc gaatcctgac cgcccgagaa gatgaccaag


 


701
gctttttggt ttga






This corresponds to the amino acid sequence <SEQ ID 1048; ORF 261.ng>:










g261.pep




1
MELGHIVFLV LCARSDGLFT FQTFRQPAFA QDTARAFAAA ADDTLVAGVG



 


51
LFADVVQHAH FVRQRPRLRL GQVHQRRVDL KIVVHRQIKG NVHGFDEHAA


 


101
AVGIARKIGF AHARDDVPDT LPFGKNGGVK QEKRVTPVHK GIGNAVVGGF


 


151
DGGGFDGGGF VHQGVVRNLP HQAQIEYGLT DTQILRDPLC AFQLDGMALP


 


201
VSEGDGLDVF APVGLDCLNQ AGGRILTARE DDQGFLV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1049>:










m261.seq




1
ATGGAGCTTG GGCATATCGT ATTCCTTATG GTTTGCGCGT GTTCAGACGG



 


51
CCTTTTTACT TTCCAGATAT TCCGCCAGCC cGcGTTCGCG CAAGATACAG


 


101
CTCGGGCATT CGCGgCAGCC GCCGACGATG CCGTTATAGC AGGTGTGGGT


 


151
TTGCTCGCGG ATATAGTCCA GCACGCCCAT TTCGTCCGCC AACGCCCACG


 


201
TTTGCGCCTT GGTCAGATAC ATCAGCGGCG TGTGGATTTG AAAATCATAG


 


251
TCCATCGCCA AATTAAGGGT AACGTTCATC GATTTGACAA ACACGTCGCG


 


301
GCAGTCGGGA TAGCCGGAGA AGTCGGTTTC GCACACGCCC GCGATGATGT


 


351
GCCGTATCCC CTGCCCTTTG GCGTAAATCG CGGCATAGAG CAGGAAAAGC


 


401
gCGTTGCGGC CGTCTACAAA GGTATTCGGA ACGCCGTTTT CGGCAGTTTC


 


451
GATGGCGGCG GTGTCGTCCA TCAGGGCATT GTGCGTAATC TGCCGCATCA


 


501
GgCTcAAGTC GAGTACGGTT TGTTTGACGC CCAAATCCTG CGCAATCCAG


 


551
CGGGCACGTT CCAGCTCGAC GGCATGGCGT TGCCCGTATT GGAAAGTAAT


 


601
GGCTTGGACG TTTTCGCGCC CGTAGGTTTG GATTGCCTGA ATCAGGCAGG


 


651
TGGTCGAATC CTGACCGCCC GAAAAGATGA CCAAGGCTTG TTGGTTTGA






This corresponds to the amino acid sequence <SEQ ID 1050; ORF 261>:










m261.pep




1
MELGHIVFLM VCACSDGLFT FQIFRQPAFA QDTARAFAAA ADDAVIAGVG



 


51
LLADIVQHAH FVRQRPRLRL GQIHQRRVDL KIIVHRQIKG NVHRFDKHVA


 


101
AVGIAGEVGF AHARDDVPYP LPFGVNRGIE QEKRVAAVYK GIRNAVFGSF


 


151
DGGGVVHQGI VRNLPHQAQV EYGLFDAQIL RNPAGTFQLD GMALPVLESN


 


201
GLDVFAPVGL DCLNQAGGRI LTARKDDQGL LV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 261 shows 79.7% identity over a 237 aa overlap with a predicted ORF (ORF 261.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1051>:










a261.seq




1
ATGGAGCTTG GGCATATCGT ATTCCTTATG GTTTGCGCGT GTTCAGACGG



 


51
CCTTTTTACT TTCCAGATAT TCCGCCAGCC CGCGTTCGCG CAAGATACAG


 


101
CTCGGGCATT CGCGGCAGCC GCCGACGATG CCGTTATAGC AGGTGTGGGT


 


151
TTGCTCGCGG ATATAGTCCA GCGCGCCCAT TTCGTCCGCC AACGCCCAAG


 


201
TTTGCGCCTT GGTCAGATAC ATCAGCGGCG TGTGGATTTG AAAATCATAG


 


251
TCCATCGCCA GATTAAGGGT AACGTTCATG GATTTGACAA ACACGTCACG


 


301
GCAGTCGGGA TAGCCGGAGA AGTCGGTTTC GCACACGCCC GCGATGATGT


 


351
GCCGTATCCC CTGCCCTTTG GCGTAAATCG CGGCATAGAG CAGGAAAAGC


 


401
GCGTTGCGGC CGTCTACAAA GGTATTCGGA ACGCCGTTTT CGGCAGTTTC


 


451
GATGGCGGCG GTGTCGTCCA TCAGGGCATT GTGCGTAATC TGCCGCATCA


 


501
GGCTCAAGTC GAGTACGGTT TGTTTGACGC CCAAATCCTG CGCAATCCAG


 


551
CGGGCACGTT CCAGCTCGAC GGCATGGCGT TGCCCGTATT GGAAAGTAAT


 


601
GGCTTGGACG TTTTCGCGCC CGTAGGTTTG GATTGCCTGA ATCAGGCAGG


 


651
TGGTCGAATC CTGACCGCCC GAAAAGATGA CCAAGGCTTT TTGGTTTGA






This corresponds to the amino acid sequence <SEQ ID 1052; ORF 261.a>:










a261.pep




1
MELGHIVFLM VCACSDGLFT FQIFRQPAFA QDTARAFAAA ADDAVIAGVG



 


51
LLADIVQRAH FVRQRPSLRL GQIHQRRVDL KIIVHRQIKG NVHGFDKHVT


 


101
AVGIAGEVGF AHARDDVPYP LPFGVNRGIE QEKRVAAVYK GIRNAVFGSF


 


151
DGGGVVHQGI VRNLPHQAQV EYGLFDAQIL RNPAGTFQLD GMALPVLESN


 


201
GLDVFAPVGL DCLNQAGGRI LTARKDDQGF LV*






m261/a261 97.8% identity in 232 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1053>:










g263.seq




1
atggcacgtt taaccgtaca caccctcgaa accgcccccg aagccgccaa



 


51
accgcgcgta gaggccgtac ccaaaaacaa cggctttatc cccaacctca


 


101
tcggcgtatt ggcaaacgcc cccgaagctt tggcgtttta ccaagaagtc


 


151
ggcaagctca acgccgccaa cagcctgacc gccggcgaag tcgaagtgat


 


201
ccggatcatc gccgtccgca ccaaccaatg cagcttctgc gtggcagggc


 


251
acaccaaact cgcaaccctg aaaaaactcc tgtccgagca atccctcaat


 


301
gccgcccgcg ctttggcggc aggtaaatct gacgatgcca aactcggcgc


 


351
gcttgccgcc ttcacccaag ccgtaatggc gaaaaaaggc gcagtatccg


 


401
acgacgaact caacgccttc ctcgaagcgg gctacaaccg gcagcaggca


 


451
gtcgaagtcg taatgggcgt agccttggca actttgtgca actacgccaa


 


501
caacctcgcc caaaccgaaa tcaaccccaa attgcaggca tacgcctaa






This corresponds to the amino acid sequence <SEQ ID 1054; ORF 263.ng>:










g263.pep




1
MARLTVHTLE TAPEAAKPRV EAVPKNNGFI PNLIGVLANA PEALAFYQEV



 


51
GKLNAANSLT AGEVEVIRII AVRTNQCSFC VAGHTKLATL KKLLSEQSLN


 


101
AARALAAGKS DDAKLGALAA FTQAVMAKKG AVSDDELNAF LEAGYNRQQA


 


151
VEVVMGVALA TLCNYANNLA QTEINPKLQA YA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1055>:









m263.seq (partial)










1
..GCAGCAGGCG AATTTGACGA TGCCAAACTC GGCGCGCTCG CCGCCTTCAC



 


51
  CCAAGCCGTA ATGGCGAAAA AAGGCGCGGT ATCCGACGAG GAACTCAAAG


 


101
  CATTTTTCGA TGCGGGCTAC AACCAGCAGC AGGCAGTCGA AGTCGTGATG


 


151
  GGCGT.AsyC TgGCAACCCT GTGCAACTAC GTCAACAACC TCGGACAAAC


 


201
  CGAAATCAAC CCCGAATTGC AGGCTTACGC CTGA






This corresponds to the amino acid sequence <SEQ ID 1056; ORF 263>:









m263.pep (partial)










1
..GCAGCAGGCG AATTTGACGA TGCCAAACTC GGCGCGCTCG CCGCCTTCAC



 


51
  CCAAGCCGTA ATGGCGAAAA AAGGCGCGGT ATCCGACGAG GAACTCAAAG


 


101
  CATTTTTCGA TGCGGGCTAC AACCAGCAGC AGGCAGTCGA AGTCGTGATG


 


151
  GGCGT.AsyC TgGCAACCCT GTGCAACTAC GTCAACAACC TCGGACAAAC


 


201
  CGAAATCAAC CCCGAATTGC AGGCTTACGC CTGA






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 263 shows 85.7% identity over a 77 aa overlap with a predicted ORF (ORF 263.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1057>:










a263.seq




1
ATGGCACGTT TAACCGTACA CACCCTCGAA ACCGCCCCCG AAGCCGCCAA



 


51
AGCGCGCGTC GAGGCGGTAC TTCAAAACAA CGGCTTTATC CCCAACCTTA


 


101
TCGGCGTATT ATCAAACGCC CCCGAAGCCT TGGCGTTTTA CCAAGAAGTC


 


151
GGCAAGCTCA ACGCCGCCAA CAGCCTGACC GCCGGCGAAG TCGAAGTAAT


 


201
CCAGATTATT GCCGCCCGCA CCAACCAATG CGGCTTCTGC GTGGCAGGGC


 


251
ACACCAAACT CGCAACCCTG AAAAAACTCC TTTCCGAACA ATCCGTCAAA


 


301
GCCGCGCGCG CTTTGGCGGC AGGCGAATTT GACGATGCTA AACTCGGCGC


 


351
GCTCGCCGCC TTTACCCAAG CCGTAATGGC AAAAAAAGGC GCGGTATCCG


 


401
ACGAGGAACT CAAAGCATTT TTTGATGCGG GCTACAACCA GCAGCAGGCA


 


451
GTCGAAGTCG TGATGGGCGT AGCCTTGGCA ACTTTGTGCA ACTACGTCAA


 


501
CAACCTCGGA CAAACCGAAA TCAACCCCGA ATTGCAGGCT TACGCCTGA






This corresponds to the amino acid sequence <SEQ ID 1058; ORF 263.a>:










a263.pep




1
MARLTVHTLE TAPEAAKARV EAVLQNNGFI PNLIGVLSNA PEALAFYQEV


 


51
GKLNAANSLT AGEVEVIQII AARTNQCGFC VAGHTKLATL KKLLSEQSVK


 


101
AARALAAGEF DDAKLGALAA FTQAVMAKKG AVSDEELKAF FDAGYNQQQA


 


151
VEVVMGVALA TLCNYVNNLG QTEINPELQA YA*






m263/a263 97.4% identity in 77 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1059>:










g264.seq




1
ttgactttaa cccgaaaaac ccttttcctc ctcaccgccg cgttcggcac


 


51
acactccctt cagacggcat ccgccgacgc agtggtcaag ccggaaaaac


 


101
tgcacgcctc cgccaaccgc agctacaaag tcgccgaatt cacgcaaacc


 


151
ggcaacgcct cgtggtacgg cggcaggttt cacgggcgca aaacttccgg


 


201
cggagaccgc tacgatatga acgcctttac cgccgcccac aaaaccctgc


 


251
ccatccccag ccatgtgcgc gtaaccaaca ccaaaaacgg caaaagcgtc


 


301
atcgtccgcg tcaacgaccg cggccccttc cacggcaacc gcatcatcga


 


351
cgtatccaaa gccgccgcgc aaaaattggg ctttgtcagc caagggacgg


 


401
cacacgtcaa aatcgaacaa atcgtcccgg gccaatccgc accggttgcc


 


451
gaaaacaaag acatctttat cgacttgaaa tctttcggta cggaacacga


 


501
agcacaagcc tatctgaacc aagccgccca aaatttcgcc gcttcgtcat


 


551
caagcccgaa cctctcggtt gaaaaacgcc gttacgaata cgttgtcaaa


 


601
atgggcccgt ttgcctcgca ggaacgcgcc gccgaagccg aagcgcaggc


 


651
acgcggtatg gttcgggcgg tactgacctc cggttga






This corresponds to the amino acid sequence <SEQ ID 1060; ORF 264.ng>:










g264.pep




1
LTLTRKTLFL LTAAFGTHSL QTASADAVVK PEKLHASANR SYKVAEFTQT


 


51
GNASWYGGRF HGRKTSGGDR YDMNAFTAAH KTLPIPSHVR VTNTKNGKSV


 


101
IVRVNDRGPF HGNRIIDVSK AAAQKLGFVS QGTAHVKIEQ IVPGQSAPVA


 


151
ENKDIFIDLK SFGTEHEAQA YLNQAAQNFA ASSSSPNLSV EKRRYEYVVK


 


201
MGPFASQERA AEAEAQARGM VRAVLTSG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1061>:










m264.seq




1
TTGACTTTAA CCCGAAAAAC CCTTTTCCTT CTCACCGCCG CATTCGGCAC


 


51
ACACTCCCTT CAGACGGCAT CCGCCGACGC AGTGGTCAAG GCAGAAAAAC


 


101
TGCACGCCTC CGCCAACCGC AGCTACAAAG TCGCCGGAAA ACGCTACACG


 


151
CCGAAAAACC AAGTCGCCGA ATTCACGCAA ACCGGCAACG CCTCGTGGTA


 


201
CGGCGGCAGG TTTCACGGGC GCAAAACTTC CGGCGGAGAA CGATACGATA


 


251
TGAACGCCTT TACCGCCGCC CACAAAACCC TGCCCATCCC CAGCTATGTG


 


301
CGCGTAACCA ATACCAAAAA CGGCAAAAGC GTCATCGTCC GCGTCAACGA


 


351
CCGCGGCCCC TTCCACGGCA ACCGCATCAT CGACGTATCC AAAGCCGCCG


 


401
CGCAAAAATT GGGCTTTGTC AACCAAGGGA CGGCACACGT CAAAATCGAA


 


451
CAAATCGTCC CGGGCCAATC CGCACCGGTT GCCGAAAACA AAGACATCTT


 


501
TATCGACTTG AAATCTTTCG GTACGGAACA CGAAGCACAA GCCTATCTGA


 


551
ACCAAGCCGC CCAAAACTTC GCCGTTTCGT CATCGGGTAC GAACCTCTCG


 


601
GTTGAAAAAC GCCGTTACGA ATACGTCGTC AAAATGGGAC CGTTTACCTC


 


651
GCAGGAACGC GCCGCCGAAG CCGAAGCTCA GGCGCGCGGT ATGGTTCGGG


 


701
CGGTATTGAC CGCCGGCTGA






This corresponds to the amino acid sequence <SEQ ID 1062; ORF 264>:










m264.pep




1
LTLTRKTLFL LTAAFGTHSL QTASADAVVK AEKLHASANR SYKVAGKRYT


 


51
PKNQVAEFTQ TGNASWYGGR FHGRKTSGGE RYDMNAFTAA HKTLPIPSYV


 


101
RVTNTKNGKS VIVRVNDRGP FHGNRIIDVS KAAAQKLGFV NQGTAHVKIE


 


151
QIVPGQSAPV AENKDIFIDL KSFGTEHEAQ AYLNQAAQNF AVSSSGTNLS


 


201
VEKRRYEYVV KMGPFTSQER AAEAEAQARG MVRAVLTAG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 264 shows 91.6% identity over a 239 aa overlap with a predicted ORF (ORF 264.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1063>:










a264.seq




1
TTGACTTTAA CCCGAAAAAC CCTTTTCCTC CTCACCGCCG CATTCGGCAT


 


51
ACATTCCTTT CAGACGGCAT CCGCCGACGC AGTGGTCAGG GCAGAAAAAC


 


101
TGCACGCCTC CGCCAACCGC AGCTACAAAG TCGCCGGAAA ACGCTACACG


 


151
CCGAAAAACC AAGTCGCCGA ATTCACGCAA ACCGGCAACG CCTCGTGGTA


 


201
CGGCGGCAGG TTTCACGGGC GCAAAACTTC CGGCGGAGAA CGATACGATA


 


251
TGAACGCCTT TACCGCCGCC CACAAAACCC TGCCCATCCC CAGCTATGTG


 


301
CGCGTAACCA ATACCAAAAA CGGCAAAAGC GTCATCGTCC GCGTCAACGA


 


351
CCGCGGCCCC TTCCACGGCA ACCGCATCAT CGACGTATCC AAAGCCGCCG


 


401
CGCAAAAATT GGGCTTTGTC AACCAAGGGA CGGCGCACGT CAAAATCGAA


 


451
CAAATCGTCC CGGGCCAATC CGCACCGGTT GCCGAAAACA AAGACATCTT


 


501
CATCGACTTG AAATCTTTCG GTACGGAACA CGAAGCACAA GCCTATCTGA


 


551
ACCAAGCCGC CCAAAACCTG GCTTCATCGG CATCAAACCC GAACCTCTCG


 


601
GTTGAAAAAC GCCGTTACGA ATACGTCGTC AAAATGGGAC CGTTTGCCTC


 


651
GCAGGAACGC GCCGCCGAGG CCGAAGCTCA GGCGCGCGGT ATGGTTCGGG


 


701
CGGTATTAAC CGCCGGTTGA






This corresponds to the amino acid sequence <SEQ ID 1064; ORF 264.a>:










a264.pep




1
LTLTRKTLFL LTAAFGIHSF QTASADAVVR AEKLHASANR SYKVAGKRYT


 


51
PKNQVAEFTQ TGNASWYGGR FHGRKTSGGE RYDMNAFTAA HKTLPIPSYV


 


101
RVTNTKNGKS VIVRVNDRGP FHGNRIIDVS KAAAQKLGFV NQGTAHVKIE


 


151
QIVPGQSAPV AENKDIFIDL KSFGTEHEAQ AYLNQAAQNL ASSASNPNLS


 


201
VEKRRYEYVV KMGPFASQER AAEAEAQARG MVRAVLTAG*






m264/a264 96.2% identity in 239 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1065>:










m265.seq




1
ATGTCGGTGA TTTTGCCGCC GACACGCGCC AACGCTGCTT TTTCGGCTTG


 


51
GGCGCGGCTG ATGATTTTGT CTTGTTTGTT GTGTTGGTGT GCGGCGTGTC


 


101
CGTGGTCGTC ATCGCCGTGT CCGTCGTGGT GGGCGAGCGC GGGGGCGGAA


 


151
ATGCTCAGCA GTGCGGTTGC GGCGGAGGTC AAGAGAAGGT GTTTGATGTT


 


201
CATAT.TTTT GCCTTTGTAA ATCGTGGGTT GGAAAATGTG GATATTAATA


 


251
AGGTATCAAA TAACCGTCAG CCGGCGGTCA ATACCGCCCG AACCATACCG


 


301
CGCGCCTGAG CTTCGGCTTC GGCGGCGCGT TCCTGCGAGG TAAACGGTCC


 


351
CATTTTGACG ACGTATTCGT AA






This corresponds to the amino acid sequence <SEQ ID 1066; ORF 265>:










m265.pep




1
MSVILPPTRA NAAFSAWARL MILSCLLCWC AACPWSSSPC PSWWASAGAE


 


51
MLSSAVAAEV KRRCLMFIXF AFVNRGLENV DINKVSNNRQ PAVNTARTIP


 


101
RAXASASAAR SCEVNGPILT TYS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 265 shows 88.6% identity over a 123 aa overlap with a predicted ORF (ORF 265.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1067>:










a265.seq




1
ATGTCGGTGA TTTTGCCGCC GACACGCGCC AACGCTGCTT TTTCGGCTTG


 


51
GGCGCGGCTG ATGATTTTGT CTTGTTTGCT GTGTTGGTGT GCGGCGTGTC


 


101
CGTGGTCGTC ATCGCCGTGT CCGTCGTGGT GGGCGAGTGC GGGGGCGGAA


 


151
ATGCCCATCA GTGCGGTTGC GGCGGCGGTC AAGAGAAGGC GTTTGAAGTT


 


201
CATTTTTGCT CCTGCGAAGT ATCTGGT... .....GGTGT TTGAAGGACG


 


251
TAAAGGCGGG ACATCAACCG GCGGTTAATA CCGCCCGAAC CATACCGCGC


 


301
GCCTGAGCTT CGGCCTCGGC GGCGCGTTCC TGCGAGGCAA ACGGTCCCAT


 


351
TTTGACGACG TATTCGTAA






This corresponds to the amino acid sequence <SEQ ID 1068; ORF 265.a>:










a265.pep




1
MSVILPPTRA NAAFSAWARL MILSCLLCWC AACPWSSSPC PSWWASAGAE


 


51
MPISAVAAAV KRRRLKFIFA PAKYLX..XC LKDVKAGHQP AVNTARTIPR


 


101
A*ASASAARS CEANGPILTT YS*






m265/a265 79.7% identity in 123 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1069>:










g266.seq




1
agttcagacg gcatcgccgc cgacaatgcc caaacagaaa gcccatcatg


 


51
accgcatcca tgtacatcct tttggtcttg gcactcatct ttgccaacgc


 


101
ccccttcctc acgaccagac tgttcggcgt ggccgcgctc aagcgcaaac


 


151
atttcggaca ccacctgatc gagctggcgg caggtttcgc gctgaccgcc


 


201
tctcttgcct acatcctcga atcccgtgcg ggagcggtac acaatcaggg


 


251
ttgggagttt tacgccaccg tcgtctgcct gtacctcatt ttcgccttcc


 


301
cgtgtttcgt gcggcggtat ttttggcaca cgcgcaacag ggaataa






This corresponds to the amino acid sequence <SEQ ID 1070; ORF 266.ng>:










g266.pep




1
MQFRRHRRRQ CPNRKPIMTA SMYILLVLAL IFANAPFLTT RLFGVAALKR


 


51
KHFGHHLIEL AAGFALTASL AYILESRAGA VHNQGWEFYA TVVCLYLIFA


 


101
FPCFVRRYFW HTRNRE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1071>:










m266.seq




1
ATGCCGTTCC GCAACGCGtT cAGACGGCAT CGCCGCCGAC AACGCCTAAA


 


51
CAGAAAGCCC ACCATGACCG CATCCATGTA CATCCTTTTG GTCTTGGCAC


 


101
TCATCTTTGC CAACGCCCCC TTCCTCACGA CCAGACTGTT CGGCGTGGCC


 


151
rCACTCAAGC GCAAACATTT CGGACACCAC ATGATCGAGC TGGCGGCAGG


 


201
TTTCGCGCTG ACCGCCGTTC TTGCCTACAT CCTsGAATCC CGTGCAGGAT


 


251
CGGTACACGA TCAGGGTTGG GAGTTTTATG CCACAGTCGT CTGCCTGTAC


 


301
CTGATTTTTG CGTTTCCATG TTTTGTGTGG CGGTATTTTT GGCACACGCG


 


351
CAACAGGGAA TAG






This corresponds to the amino acid sequence <SEQ ID 1072; ORF 266>:










m266.pep




1
MPFRNAFRRH RRRQRLNRKP TMTASMYILL VLALIFANAP FLTTRLFGVA


 


51
XLKRKHFGHH MIELAAGFAL TAVLAYILES RAGSVHDQGW EFYATVVCLY


 


101
LIFAFPCFVW RYFWHTRNRE *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 266 shows 92.1% identity over a 114 aa overlap with a predicted ORF (ORF 266.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1073>:










a266.seq




1
ATGCCGTTCC GCAATGCGTT CAGACGGCAT CGCCGCCGAC AATGCCCAAA


 


51
CAGAAAGCCC GCCATGACCG CATCCATGTA CATCCTTTTG CTGCTTGCCT


 


101
TGATTTTTGC CAACGCCCCC TTCCTCACGA CCAAGCTGTT CGGCATCGTA


 


151
CCGCTCAAGC GCAAACATTT CGGACACCAC CTGATCGAGC TGGCGGCAGG


 


201
TTTCGCGCTG ACCGCCGTTC TTGCCTACAT CCTCGAATCC CGTGCGGGAG


 


251
CGGTACACGA TCAGGGTTGG GAGTTTTACG CCACCGTCGT CTGCCTGTAC


 


301
CTGATTTTTG CGTTTCCCTG TTTCGTGTGG CGGTATTTTT GGCACACGCG


 


351
CAACAGGGAA TAG






This corresponds to the amino acid sequence <SEQ ID 1074; ORF 266.a>:










a266.pep




1
MPFRNAFRRH RRRQCPNRKP AMTASMYILL LLALIFANAP FLTTKLFGIV


 


51
PLKRKHFGHH LIELAAGFAL TAVLAYILES RAGAVHDQGW EFYATVVCLY


 


101
LIFAFPCFVW RYFWHTRNRE *






m266/a266 91.7% identity in 120 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1075>:










g267.seq




1
atgcaagtcg ccttttttct cgccgtggta ttcaaaaata tgggtttcca


 


51
caatcgcatc ggtcgggcag gcctcttcgc agaaaccgca gaagatgcac


 


101
ttggtcaggt cgatgtcgta acgcttggtg cggcgggtgc cgtcttcgcg


 


151
ttcttccgat tcgatgttga tcgccattgc cggacacacc gcctcgcaca


 


201
atttacacgc gatgcagcgt tcctctccgt tcggaaaacg gcgttgcgcg


 


251
tgcagaccgc ggaaacgcac ggattgcggc gttttctctt cgggaaaata


 


301
aattgtgtct ttgcgggcaa aaaagttttt gagcgttacg cccatgcctt


 


351
tgaccagttc gccaagcaga aaggttttta ctaa






This corresponds to the amino acid sequence <SEQ ID 1076; ORF 267.ng>:










g267.pep




1
MQVAFFLAVV FKNMGFHNRI GRAGLFAETA EDALGQVDVV TLGAAGAVFA


 


51
FFRFDVDRHC RTHRLAQFTR DAAFLSVRKT ALRVQTAETH GLRRFLFGKI


 


101
NCVFAGKKVF ERYAHAFDQF AKQKGFY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1077>:










m267.seq




1
GTGCAAGTCG CCTTTTTTCT CGCCGTGGTA TTCAAAAATA TGGGTTTCCA


 


51
CAATCGCATC AGTCGGGCAT GCCTCTTCGC AGAAACCGCA GAAGATGCAC


 


101
TTGGTCAGGT CGATGTCGTA ACGCTTGGTG CGGCGCGTAC CGTCTTCACG


 


151
TTCTTCCGAT TCGATGTTAA TCGCCATTGC CGGACACACT GCCTCACACA


 


201
ACTTACACGC GATACACCGC TCTTCGCCGT TCGGATACCG CcGCTGCGCG


 


251
TGCAGACCGC GGAAACGCAC GGATTGCGGC GTTTTCTCTT CGGGGAAATA


 


301
AATTGTGTCT TTGCGGGCGA AAAAGTTTTT GAGCGTTACG CCCATACCTT


 


351
TTACCAATTC GCCAAGCAGA AAGGTTTTTA CTAA






This corresponds to the amino acid sequence <SEQ ID 1078; ORF 267>:










m267.pep




1
VQVAFFLAVV FKNMGFHNRI SRACLFAETA EDALGQVDVV TLGAARTVFT


 


51
FFRFDVNRHC RTHCLTQLTR DTPLFAVRIP PLRVQTAETH GLRRFLFGEI


 


101
NCVFAGEKVF ERYAHTFYQF AKQKGFY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 267 shows 82.7% identity over a 127 aa overlap with a predicted ORF (ORF 267.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1079>:










a267.seq




1
GTGCAAGTCG CCTTTTTTCT CGCCGTGGTA TTCAAAAATA TGGGTTTCCA


 


51
CAATCGCATC GGTCGGGCAG GCTTCTTCGC AGAAACCGCA GAAGATGCAC


 


101
TTGGTCAGGT CGATGTCGTA ACGCTTGGTG CGGCGCGTGC CGTCTTCGCG


 


151
TTCTTCCGAT TCGATGTTGA TCGCCATTGC GGGGCAAACG GCTTCACACA


 


201
ATTTACACGC GATGCAGCGT TCCTCGCCGT TTGGATAACG GCGTTGCGCG


 


251
TGCAGACCGC GGAAACGCAC GGATTGCGGC GTTTTCTCTT CGGGAAAATA


 


301
AATCGTGTCT TTGCGGGCAA AAAAGTTTTT GAGCGTTACG CCCATACCTT


 


351
TTACCAATTC GCCAAGCAGA AAGGTTTTTA CTAA






This corresponds to the amino acid sequence <SEQ ID 1080; ORF 267.a>:










a267.pep




1
VQVAFFLAVV FKNMGFHNRI GRAGFFAETA EDALGQVDVV TLGAARAVFA


 


51
FFRFDVDRHC GANGFTQFTR DAAFLAVWIT ALRVQTAETH GLRRFLFGKI


 


101
NRVFAGKKVF ERYAHTFYQF AKQKGFY*






m267/a267 82.7% identity in 127 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1081>:










G268.seq




1
atgaaaaaaa atttacccgc actggcattg gcaagtatgc tgattttgtc


 


51
gggctgcgac cgtttgggaa taggcaaccc gttttccgga aaggaaattt


 


101
cctgcggaag cgaagagact aaagagattt tggtcaaact ggtccgcgac


 


151
aatgtcgaag gtgaaaccgt caaaactttt gacgacgacg cattcaaaga


 


201
ccaagcattt gccgatatcg gcatatcgca tatccgcaga atggtcgaac


 


251
gtttgggcat aaccgtcgat gaagtccgaa ctaccgagaa aaccgacacg


 


301
tccagcaaac tcaaatgtga agccgcgtta aaactggacg tgcccgacga


 


351
tgttgtcgat tatgccgtcg ccgccaacca atctataggc aacagccata


 


401
agaaaacgcc cgactttttt gaaccctact accgcaaaga aggcgcgtat


 


451
tatgtcaaaa ctatttctta cagcgtccag ccgacagacg acaaaagcaa


 


501
aatctttgcc gaactcagtc aggcacacga tatcatccat ccgctcagcg


 


551
agctggtgtc tatggcactg attaaagagc cgttggacaa agcgaaacaa


 


601
aggaacgaaa aacttgaagc ggcagaagcc accgcgcagg aagcgaggga


 


651
ggcagaagaa gcggcggcgc aggaggcatt gggtcgggag caggaagccg


 


701
cccgcgtatc cgaatgggaa gaacgctaca agctgtcgcg cagcgagttc


 


751
gagcagtttt ggaaaggatt gcctcaaact gtacagaata agctgcaagc


 


801
ctcgcagaaa acatggaaaa gcggtatgga caagatctgt gccaacaatg


 


851
cgaaagccga aggtgaaacg ccaaacggca taaaagtcag tgagttggcg


 


901
tgtaaaacgg cagaaaccga agcacgcttg gaagagctgc acaaccgtaa


 


951
aaaagccctt atcgacgaaa tggtcaggga agaggacaag aaagaactgc


 


1001
caaagcggct ctga






This corresponds to the amino acid sequence <SEQ ID 1082; ORF 268.ng>:










m268.pep




1
MKKNLPALAL ASMLILSGCD RLGIGNPFSG KEISCGSEET KEILVKLVRD


 


51
NVEGETVKTF DDDAFKDQAF ADIGISHIRR MVERLGITVD EVRTTEKTDT


 


101
SSKLKCEAAL KLDVPDDVVD YAVAANQSIG NSHKKTPDFF EPYYRKEGAY


 


151
YVKTISYSVQ PTDDKSKIFA ELSQAHDIIH PLSELVSMAL IKEPLDKAKQ


 


201
RNEKLEAAEA TAQEAREAEE AAAQEALGRE QEAARVSEWE ERYKLSRSEF


 


251
EQFWKGLPQT VQNKLQASQK TWKSGMDKIC ANNAKAEGET PNGIKVSELA


 


301
CKTAETEARL EELHNRKKAL IDEMVREEDK KELPKRL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1083>:









m268.seq (partial)










1
..ATGGCACTGA TTAAAGAGCC GTTGGACAAA GTGAAACAAA GGAACGAAGA



 


51
  ACTTGAAGCG GCAGAAGAAG CGGCGGCGCA GGAGGCATTG GGTCGGGAGC


 


101
  AGGAAGCCGC CCGCGTATCC GAATGGGAAG AACGCTACAA GCTGTCGCGC


 


151
  AG.CAGTTCG AGCAGTTCTG GAAAGGATTG CCTCAAACCG TACAGAATAA


 


201
  GCTGCAACCn TCACAGAAAA CATGGAAAAG CGGGATGGAT AAAATCTGTG


 


251
  CCAACAATGC GAAAGCTGAA GGTAAAACGC CAAACGGCAT AAAATTCAGC


 


301
  GAACTGGCAT GCAAAACGGC GAAAACCGAA GCACGCTTGG AAGAGCTGCA


 


351
  CAACCGTAAA AAAGCCCTTA TCGACGAAAT GGyCAGGGAA GCGGACAmGA


 


401
  AAGAACTGTC AAAGCGGCTs TGA






This corresponds to the amino acid sequence <SEQ ID 1084; ORF 268>:









m268.pep (partial)










1
..MALIKEPLDK VKQRNEELEA AEEAAAQEAL GREQEAARVS EWEERYKLSR



 


51
  XQFEQFWKGL PQTVQNKLQP SQKTWKSGMD KICANNAKAE GKTPNGIKFS


 


101
  ELACKTAKTE ARLEELHNRK KALIDEMXRE ADXKELSKRL *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 268 shows 86.0% identity over a 150 aa overlap with a predicted ORF (ORF 268.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1085>:










a268.seq




1
ATGGCACTGA TTAAAGAGCC GTTGGACAAA GCGAAACAAA GGAACGAAGA


 


51
ACTTGAAGCG GCAGAAGAAG CGGCGGCGCA GGAGGCATTG GGTCGGGAGC


 


101
AGGAAGTCGA CCGCGTATCC GAATGGGAAG AACGCTACAA GCTGTCGCGC


 


151
AGCGAGTTCG AGCAGTTCTG GAAAGGATTG CCTCAAACCG TACAGAATAA


 


201
GCTGCAAGCC TCACAGAAAA CATGGAAAAG CGGGATGGAT AAAATCTGTG


 


251
CCAACAATGC GAAAGCTGAA GGTGAAACGC CAAACGGCAT AAAATTCAGC


 


301
GAACTGGCAT GCAAAACGGC GGAAACCGAA GCACGCTTGG AAGAGCTGCA


 


351
CAACCGTAAA AAAGCCCTTC TCGACGAAAT GGCCAGGGAA GCGGACAAGA


 


401
AAGAACTGCC AAAGCGGCTC TGA






This corresponds to the amino acid sequence <SEQ ID 1086; ORF 268.a>:










a268.pep




1
MALIKEPLDK AKQRNEELEA AEEAAAQEAL GREQEVDRVS EWEERYKLSR


 


51
SEFEQFWKGL PQTVQNKLQA SQKTWKSGMD KICANNAKAE GETPNGIKFS


 


101
ELACKTAETE ARLEELHNRK KALLDEMARE ADKKELPKRL *






m268/a268 91.4% identity in 140 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1087>:










m268-1.seq




1
GTGCAATCCC GATATGATGG TTTGCATAAA TTTAAACATA TATGTTCCGC


 


51
AGCTATGGCA CTGATTAAAG AGCCGTTGGA CAAAGTGAAA CAAAGGAACG


 


101
AAGAACTTGA AGCGGCAGAA GAAGCGGCGG CGCAGGAGGC ATTGGGTCGG


 


151
GAGCAGGAAG CCGCCCGCGT ATCCGAATGG GAAGAACGCT ACAAGCTGTC


 


201
GCGCAGCGAG TTCGAGCAGT TCTGGAAAGG ATTGCCTCAA ACCGTACAGA


 


251
ATAAGCTGCA AGCCTCACAG AAAACATGGA AAAGCGGGAT GGATAAAATC


 


301
TGTGCCAACA ATGCGAAAGC TGAAGGTAAA ACGCCAAACG GCATAAAATT


 


351
CAGCGAACTG GCATGCAAAA CGGCGAAAAC CGAAGCACGC TTGGAAGAGC


 


401
TGCACAACCG TAAAAAAGCC CTTATCGACG AAATGGCCAG GGAAGCGGAC


 


451
AAGAAAGAAC TGTCAAAGCG GCTCTGA






This corresponds to the amino acid sequence <SEQ ID 1088; ORF 268-1>:










m268-1.pep




1
VQSRYDGLHK FKHICSAAMA LIKEPLDKVK QRNEELEAAE EAAAQEALGR


 


51
EQEAARVSEW EERYKLSRSE FEQFWKGLPQ TVQNKLQASQ KTWKSGMDKI


 


101
CANNAKAEGK TPNGIKFSEL ACKTAKTEAR LEELHNRKKA LIDEMAREAD


 


151
KKELSKRL*






m268-1/g268 82.3% identity in 164 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1089>:










a268-1.seq




1
GTGCAATCCC GATATGATGG TTTGCATAAA TTTAAACATA TATGTTCCGC


 


51
AGCTATGGCA CTGATTAAAG AGCCGTTGGA CAAAGCGAAA CAAAGGAACG


 


101
AAGAACTTGA AGCGGCAGAA GAAGCGGCGG CGCAGGAGGC ATTGGGTCGG


 


151
GAGCAGGAAG TCGACCGCGT ATCCGAATGG GAAGAACGCT ACAAGCTGTC


 


201
GCGCAGCGAG TTCGAGCAGT TCTGGAAAGG ATTGCCTCAA ACCGTACAGA


 


251
ATAAGCTGCA AGCCTCACAG AAAACATGGA AAAGCGGGAT GGATAAAATC


 


301
TGTGCCAACA ATGCGAAAGC TGAAGGTGAA ACGCCAAACG GCATAAAATT


 


351
CAGCGAACTG GCATGCAAAA CGGCGGAAAC CGAAGCACGC TTGGAAGAGC


 


401
TGCACAACCG TAAAAAAGCC CTTCTCGACG AAATGGCCAG GGAAGCGGAC


 


451
AAGAAAGAAC TGCCAAAGCG GCTCTGA






This corresponds to the amino acid sequence <SEQ ID 1090; ORF 268-1.a>:










a268-1.pep




1
VQSRYDGLHK FKHICSAAMA LIKEPLDKAK QRNEELEAAE EAAAQEALGR


 


51
EQEVDRVSEW EERYKLSRSE FEQFWKGLPQ TVQNKLQASQ KTWKSGMDKI


 


101
CANNAKAEGE TPNGIKFSEL ACKTAETEAR LEELHNRKKA LLDEMAREAD


 


151
KKELPKRL*






a268-1/m268-1 95.6% identity in 158 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1091>:










g269.seq




1
atggtttggc gtgtgaattg cgcggcaacg gcggcgctga ttttttcgtc


 


51
cagcccttgg atttgggcgg tggtgtgggt gtggtcgcgg tcggcttttt


 


101
cctgcaaacc ttgcgccagc cttgacgcgt ccagtgcgcc ggcgttggcg


 


151
gtttcgccgt gggactttat ccggaacacg gcttcgccca aggtgtcggc


 


201
ggctttgatg cacagtttta aaaccagggc tttggggcgg ttttctgcgc


 


251
cgcccgttgc cattttgctg tccaatcgcg gggttaaaaa accgttgtcg


 


301
tttaagtcgc cgtccgtcca agtcgatacg agcgcgcttc tttgcctttc


 


351
attgcggtct tcgtaa






This corresponds to the amino acid sequence <SEQ ID 1092; ORF 269.ng>:










g269.pep




1
MVWRVNCAAT AALIFSSSPW IWAVVWVWSR SAFSCKPCAS LDASSAPALA


 


51
VSPWDFIRNT ASPKVSAALM HSFKTRALGR FSAPPVAILL SNRGVKKPLS


 


101
FKSPSVQVDT SALLCLSLRS S*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1093>:










m269.seq




1
ATGGTTTGGC GTGTGAATTG CGCGGCAACG GCGGTGCTGA TTTTTTCGTC


 


51
CAGCCCTTGG ATTTGGGCGG CGGTGTGGGT GTGGTCTCGG TCGGCTTTGT


 


101
CTTGCAAACC TTGCGCCaCG TGCCCGCGTC CAGCGCCTGC GTTGATGGTT


 


151
TCGCCGTGGG ACTTTATCCA AAACACGGCT TCGCCCAAGG TGTCGGCGGC


 


201
TTTGATGCAC AGTTTTAAAA CCAGGGCTTT GGGGCGGTTT TCGTCGCCGC


 


251
CTGTCGCCAT TTTGCTGTCC GAGCGCGGGG TTAAAAAGCC GTTGTCGTTT


 


301
AAATTTTCGT CCGTCCAAGT CGATACGAGC GCGCTTCTCT GCCTTTCGTT


 


351
GCGGTCTTCG TAA






This corresponds to the amino acid sequence <SEQ ID 1094; ORF 269>:










m269.pep




1
MVWRVNCAAT AVLIFSSSPW IWAAVWVWSR SALSCKPCAT CPRPAPALMV


 


51
SPWDFIQNTA SPKVSAALMH SFKTRALGRF SSPPVAILLS ERGVKKPLSF


 


101
KFSSVQVDTS ALLCLSLRSS *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 269 shows 87.6% identity over a 121 aa overlap with a predicted ORF (ORF 269.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1095>:










a269.seq




1
ATGGTTTGGC GTGTGAATTG CGCGGCAACG GCGGTGCTGA TTTTTTCGTC


 


51
CAGCCCTTGG ATTTGGGCGG CGGTGTGGGT GTGGGCGCGG TCTGCTTTGT


 


101
CTTGGAGGTT TTGCGCCAGC GTGCCCGCGT CCAGCGCGCC GGCGTTGACG


 


151
GTTTCGCCGT GGGACTTTAT CCAGAACACG GCTTCGCCCA AGGTGTCGGC


 


201
GGCTTTGATG CACAGTTTTA AAACCAGGGC TTTGGGGCGG TTTTCGTCGC


 


251
CGCCTGTCGC CATTTTGCTG TCCGGGCGCG GGGTTAAAAA GCCGTTGTCG


 


301
TTTAAATTTT CGTCCGTCCA AGTCGATACG AGCGCGCTTC TCTGCCTTTC


 


351
GTTGTGGTCT TCGTAA






This corresponds to the amino acid sequence <SEQ ID 1096; ORF 269.a>:










a269.pep




1
MVWRVNCAAT AVLIFSSSPW IWAAVWVWAR SALSWRFCAS VPASSAPALT


 


51
VSPWDFIQNT ASPKVSAALM HSFKTRALGR FSSPPVAILL SGRGVKKPLS


 


101
FKFSSVQVDT SALLCLSLWS S*






m269/a269 90.1% identity in 121 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1097>:










g270.seq




1
atgaataaaa accgcaaatt actgcttgcc gcactgctgc tgactgcctt


 


51
tgccgccttc aagctcgttt tgttgcaatg gtggcaggcg cagcagccgc


 


101
aagccgtggc ggcgcaatgc gatttgaccg agggttgcac gctgccggac


 


151
ggaagccgtg tccgcgccgc cgccgtttca accaaaaaac cgtttgatat


 


201
ttatatcgaa cacgcgcccg ccggcacgga acaggtcagc atcagcttca


 


251
gtatgaaaaa tatggatatg ggtttcaacc gctatatgtt cgagcggcaa


 


301
ccgtcgggga cttggcaggc agcacgcatc cgcctgcccg tctgtgtcga


 


351
aggcaggcgc gattttacgg cggacattac aatcggcagc cggacatttc


 


401
agacggcatt taccgccgaa taa






This corresponds to the amino acid sequence <SEQ ID 1098; ORF 270.ng>:










g270.pep




1
MNKNRKLLLA ALLLTAFAAF KLVLLQWWQA QQPQAVAAQC DLTEGCTLPD


 


51
GSRVRAAAVS TKKPFDIYIE HAPAGTEQVS ISFSMKNMDM GFNRYMFERQ


 


101
PSGTWQAARI RLPVCVEGRR DFTADITIGS RTFQTAFTAE *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1099>:










m270.seq




1
ATGAATAAAA ACCGTAAATT ACTGCTTGCC GCACTGCTGC TGATTGCCTT


 


51
TGCCGCCGTC AAGCTCGTTT TGTTGCAATG GTGGCAGGCG Ca.CAGCCGC


 


101
AAGCTGTGGC GGCGCAATGC GATTTGACCG AGGGTTGCAC GCTGCCGGAC


 


151
GGAAGCCGCG TCCGCGCCGC CGCcGTTTCA ACCAAAAAAC CGTTTGATAT


 


201
TTATATCGAA CACGCGCCCG CCGGCACGGA ACAGGTCAGC ATCAGCTTCA


 


251
GTATGAAAAA TATGGATATG GGTTTCaACC GCTATATGTT CGAGCGGCAA


 


301
cCGTCGGGGA CTTGGCAGGC AGTACGCATC CGCCTGCCCA TCTGTGTCGA


 


351
AGGCAGGCGC GATTTTACGG CGGACATTAC AATCGGCAGT CGGACATTTC


 


401
AGACGGCATT TACCGCCGAA TAA






This corresponds to the amino acid sequence <SEQ ID 1100; ORF 270>:










m270.pep




1
MNKNRKLLLA ALLLIAFAAV KLVLLQWWQA XQPQAVAAQC DLTEGCTLPD


 


51
GSRVRAAAVS TKKPFDIYIE HAPAGTEQVS ISFSMKNMDM GFNRYMFERQ


 


101
PSGTWQAVRI RLPICVEGRR DFTADITIGS RTFQTAFTAE *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 270 shows 96.4% identity over a 140 aa overlap with a predicted ORF (ORF 270.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1101>:










a270.seq




1
ATGAATAAAA ACCGTAAATT ACTGCTTGCC GCACTGCTGC TGATTGCCTT


 


51
TGCCGCCGTC AAGCTCGTTT TGTTGCAATG GTGGCAGGCG CAGCAGCCGC


 


101
AAGCTGTGGC GGCGCAATGC GATTTGACCG AGGGTTGCAC GCTGCCGGAC


 


151
GGAAGCCGCG TCCGCGCCGC CGCCGTTTCA ACCAAAAAAC CGTTTGATAT


 


201
TTATATCGAA CACGCGCCCG CCGGCACGGA ACAGGTCAGC ATCAGCTTCA


 


251
GTATGAAAAA TATGGATATG GGTTTCAACC GCTATATGTT CGAGCGGCAA


 


301
CCGTCGGGGA CTTGGCAGGC AGTACGCATC CGCCTGCCCA TCTGTGTCGA


 


351
AGGCAGGCGC GATTTTACGG CGGACATTAC AATCGGCAGC CGGACATTTC


 


401
AGACGGCATT TACCGCCGAA TAA






This corresponds to the amino acid sequence <SEQ ID 1102; ORF 270.a>:










a270.pep




1
MNKNRKLLLA ALLLIAFAAV KLVLLQWWQA QQPQAVAAQC DLTEGCTLPD


 


51
GSRVRAAAVS TKKPFDIYIE HAPAGTEQVS ISFSMKNMDM GFNRYMFERQ


 


101
PSGTWQAVRI RLPICVEGRR DFTADITIGS RTFQTAFTAE *






m270/a270 99.3% identity in 140 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1103>:










g271.seq




1
atgttcagtt cgcggatggc gaggatttgg gcgacggggg taacgttgtg


 


51
tatggtcagt ccgtgtccgg cgttgacgac caagcccaaa tcgccggcga


 


101
aatgcgcgcc gttttggatg cgctcgaact gcctgatttg ttcggcgtgg


 


151
ctttgtgcgt cggcatatgc gccggtgtgc agctcgacaa cgggcgcgcc


 


201
gacatcacgg gcggcttgga tttgcctgtc gtcggcatcg ataaacaagg


 


251
acacgcgtat gcccgcgtcg gtcaggattt tggcgaattc ggcgattttt


 


301
tcctgttgcg ccaatacgtc caaaccgcct tcggtcgtga tttcctgccg


 


351
tttttcaggc acgatgcaca cgtcttccgg catcacttta agcgcgtttt


 


401
cgagcatttc ttccgtcaac gccatttcaa ggttcaggcg cgtgcggatg


 


451
gcgtttttga cggcaaatac atccgcgtct ttgatgtggc ggcggtcttc


 


501
gcgcaggtgc atggtaatca ggtctgcacc gtgcgtttcg gcaaccagtg


 


551
ccgcctccac ggggctggga taa






This corresponds to the amino acid sequence <SEQ ID 1104; ORF 271.ng>:










g271.pep




1
MFSSRMARIW ATGVTLCMVS PCPALTTKPK SPAKCAPFWM RSNCLICSAW


 


51
LCASAYAPVC SSTTGAPTSR AAWICLSSAS INKDTRMPAS VRILANSAIF


 


101
SCCANTSKPP SVVISCRFSG TMHTSSGITL SAFSSISSVN AISRFRRVRM


 


151
AFLTANTSAS LMWRRSSRRC MVIRSAPCVS ATSAASTGLG *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1105>:










m271.seq




1
AwGTTCAGTT CGCGGATGGC GAGGATTTGG GCGATGGGGG TAACGTTGTG


 


51
TATGGTCAGT CCGTGTCCGG CGTTGACGAC CAAGCCCAAA TCGCCGGCGA


 


101
AATGCGCGCC GTTTTGGATG CGCTCGAACT GCCTGATTTG TTCGGCGTGG


 


151
CTGCGCGCGT CGGCATACGC GCCTGTGTGC AGCTCGACAA CGGGCGCGCC


 


201
GACATCACGG GCGGCTTGGA TTTGCCTGTC GTCGGCATCG ATAAACAAAG


 


251
ACACGCGTAT GCCTGCGTCG GTCAGGATTT TGGTGAACCC GGCGATTTTT


 


301
TCCTGTTGCG CCAATACGTC CAAACCGCCT TCGGTCGTGA TTTCCTGACG


 


351
TTTTTCAGGC ACGATGCACA CGTCTTCCGG CATCACTTTC AAAGCGTTTT


 


401
CCAACATTTC TTCCGTCAAC GCCATTTCAA GGTTCAGGCG CGTGCGGATG


 


451
GCGTTTTTGA CGGCAAACAC GTCCGCGTCT TTGATGTGGC GGCGGTCTTC


 


501
GCGCAGGTGC ATGGTAATCA AATCCGCACC GTGCGTTTCG GCAACCAGTG


 


551
CCGCCTCCAC GGGGCTGGGA TAA






This corresponds to the amino acid sequence <SEQ ID 1106; ORF 271>:










m271.pep




1
XFSSRMARIW AMGVTLCMVS PCPALTTKPK SPAKCAPFWM RSNCLICSAW


 


51
LRASAYAPVC SSTTGAPTSR AAWICLSSAS INKDTRMPAS VRILVNPAIF


 


101
SCCANTSKPP SVVISXRFSG TMHTSSGITF KAFSNISSVN AISRFRRVRM


 


151
AFLTANTSAS LMWRRSSRRC MVIKSAPCVS ATSAASTGLG *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 271 shows 95.2% identity over a 189 aa overlap with a predicted ORF (ORF 271.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1107>:










a271.seq




1
ATGTTCAGTT CGCGGATGGC GAGGATTTGG GCGATGGGGG TAACGTTGTG


 


51
TATGGTCAGT CCGTGTCCGG CGTTGACGAC CAAGCCCAAA TCGCTGGCAA


 


101
AATGCGCGCC GTTTTGGATG CGCTCGAACT GCCTGATTTG TTCGGCGTGG


 


151
CTGCGCGCGT CGGCATACGC GCCTGTGTGC AGCTCGACAA CGGGCGCGCC


 


201
GACATCACGG GCGGCTTGGA TTTGCCTGTC GTCGGCATCG ATAAACAAGG


 


251
ACACGCGTAT GCCCGCGTCG GTCAGGATTT TGGTGAATTC GGCAATTTTG


 


301
TCTTGTTGCG CCAATACGTC CAAGCCGCCT TCGGTCGTGA TTTCCTGACG


 


351
TTTTTCCGGC ACGATGCACA CGTCTTCCGG CATCACTTTA AGCGCGTTTT


 


401
CGAGCATTTC TTCCGTCAAC GCCATTTCAA GGTTCAGGCG CGTGCGGATG


 


451
GCGTTTTTGA CAGCAAACAC GTCCGCGTCT TTGATGTGGC GGCGGTCTTC


 


501
GCGCAGGTGC ATGGTAATCA GGTCGGCACC GTGCGTTTCG GCAACCAGTG


 


551
CCGCCTCCAC GGGGCTGGGA TAA






This corresponds to the amino acid sequence <SEQ ID 1108; ORF 271.a>:










a271.pep




1
MFSSRMARIW AMGVTLCMVS PCPALTTKPK SLAKCAPFWM RSNCLICSAW


 


51
LRASAYAPVC SSTTGAPTSR AAWICLSSAS INKDTRMPAS VRILVNSAIL


 


101
SCCANTSKPP SVVIS*RFSG TMHTSSGITL SAFSSISSVN AISRFRRVRM


 


151
AFLTANTSAS LMWRRSSRRC MVIRSAPCVS ATSAASTGLG *






m271/a271 96.3% identity in 189 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1109>:










g272.seq




1
atgactgcaa aggaagaact gttcgcatgg ctgcgccata tgaacaaaaa


 


51
caaaggttcc gacctgtttg tgacgaccca tttcccgccc gctatgaagc


 


101
tggacggcaa aatcacccgc atcacggacg aaccgctgac ggcggaaaaa


 


151
tgtatggaaa tcgccttttc gattatgagt gcgaagcagg cggaagaatt


 


201
ttcatcgacc aacgagtgca atttcgccat cagcctgccg gacaccagcc


 


251
gcttccgcgt caatgcgatg atacagcgcg gtgcgacggc gttggtattc


 


301
cgcgcgatta ccagcaagat tcccaagttt gaaagcctga acctgccgcc


 


351
ggccttgaag gatgttgcgc tgaaaaaacg cgggctggtt atttttgtcg


 


401
gcggcaccgg ctcgggcaaa tcgacttcgc tcgcctcgct tatcgactac


 


451
cgcaatgaaa attcgttcgg acacatcatc accatcgaag atccgatcga


 


501
gtttgtccac gaacacaaaa actgcatcat tacccagcgc gaggtcggcg


 


551
tggacacgga aaactggatg gcggcgttga aaaatacgct gcgtcaggcg


 


601
ccggatgtga tccttatcgg cgaaatccgc gaccgtgaaa caatggacta


 


651
cgccatcgcc tttgccgaaa cggggcattt gtgtatggcg acgctgcacg


 


701
ccaacagcac caatcaggcg ctcgaccgca tcatcaactt cttccccgag


 


751
gagcggcgcg aacaattgct gacggatttg tcgctcaacc ttcaggcgtt


 


801
tatttcgcaa cgcctcgttc cgcgagacgg cggcaagggc agggtggcgg


 


851
cagtcgaggt gctgctcaat tcgcccctga tttcggagtt gattcacaac


 


901
ggcaacatcc atgaaatcaa agaagtgatg aaaaaatcca ctaccctggg


 


951
tatgcagacc ttcgaccaac acctttacca attgtatgaa aaaggcgaga


 


1001
tttccttgca ggatgccttg aaaaatgccg attccgcaca tgatttgcgt


 


1051
ttggcggtac agttgcgcag ccgcagggca caaagttccg accccgattt


 


1101
ggaactgctc tga






This corresponds to the amino acid sequence <SEQ ID 1110; ORF 272.ng>:










g272.pep




1
MTAKEELFAW LRHMNKNKGS DLFVTTHFPP AMKLDGKITR ITDEPLTAEK


 


51
CMEIAFSIMS AKQAEEFSST NECNFAISLP DTSRFRVNAM IQRGATALVF


 


101
RAITSKIPKF ESLNLPPALK DVALKKRGLV IFVGGTGSGK STSLASLIDY


 


151
RNENSFGHII TIEDPIEFVH EHKNCIITQR EVGVDTENWM AALKNTLRQA


 


201
PDVILIGEIR DRETMDYAIA FAETGHLCMA TLHANSTNQA LDRIINFFPE


 


251
ERREQLLTDL SLNLQAFISQ RLVPRDGGKG RVAAVEVLLN SPLISELIHN


 


301
GNIHEIKEVM KKSTTLGMQT FDQHLYQLYE KGEISLQDAL KNADSAHDLR


 


351
LAVQLRSRRA QSSDPDLELL *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1111>:










m272.seq




1
ATGACCGCAA AGGAAGAACT GTTCGCATGG CTGCGCCATA TGAwCCAAAA


 


51
CAAAGGTTCC GACCTGTTCG TGACAACCCA TTTCCCGCCC GCAATGAAGC


 


101
TGGACGGCAA AATCACCCGC ATCACGGACG AACCGCTGAC GGCGGAAAAA


 


151
TGTATGGAAA TCGCCTTTTC GATTATGAGT GCGAAGCAGG CGGAAGAATT


 


201
TTCATCGACC AACGAGTGCA ACTTCGCCAT CAGCCTGCCG GACACCAGCC


 


251
GCTTCCGCGT CAATGCGATG ATACAGCgCG GCGCGACGGC GTTGGTATTC


 


301
CGTACGATTA CCAGCAAGAT TCCCAAGTTT GAAAGCCTGA ACCTGCCGCC


 


351
AGTCTTGAAG GATGTCGCGC TGAAAAAACG CGGGCTGGTT ATTTTTGTCG


 


401
GCGGCACCGG CTCGGGTAAA TCGACTTCGC TTGCCTCGCT TATCGACTAC


 


451
CGCAATGAAA ATTCGTTCGG ACACATCATC ACCATCGAAG ACCCGATCGA


 


501
GTTTGTCCAC GAACACAAAA ACTGCATCAT CACCCAGCGC GAGGTCGGCG


 


551
TGGATACGGA AAACTGGATG GcGGCGTTGA AAAACACGCT GCGTCAGGCG


 


601
CCTGATGTCA TCCTTATCGG CGAAATCCGT GACCGCGAAA CAATGGACTA


 


651
CGCCATTGCC TTTGCCGAAA CGGGGCATTT GTGTATGGCG ACGCTGCACG


 


701
CCAACAGCAC CAATCAGGCA CTCGACCGCA TCATCAACTT TTTCCCCGAG


 


751
GAGCGGCGCG AACAATTGCT GACGGATTTG TCGCTCAACC TTCAGGCGTT


 


801
TATTTCGCAA CGCCTCGTTC CGCGAGACGG CGGCAAGGGC AGGGTGGCGG


 


851
CAGTCGAGGT GCTGCTCAAT TCGCCCCtGA TTTCGGAGTT GATTCACAAC


 


901
GGCAACATCC ATGAAATCAA AGAAGTGATG AAAAAATCCA CTACCCTGGG


 


951
TATGCAGACC TTCGATCAAC ACCTTTACCA ATTGTATGAA AAAGGCGATA


 


1001
TTTCCCTGCA AGAAGCATTG AAAAATGCCG ATTCCGCACA CGATTTGCGT


 


1051
TTGGCGGTAC AGTTGCGCAG CCGCCGCGCG CAaAGTTyCA GCCCCGATTT


 


1101
GGnACTGCTC TGA






This corresponds to the amino acid sequence <SEQ ID 1112; ORF 272>:










m272.pep




1
MTAKEELFAW LRHMXQNKGS DLFVTTHFPP AMKLDGKITR ITDEPLTAEK


 


51
CMEIAFSIMS AKQAEEFSST NECNFAISLP DTSRFRVNAM IQRGATALVF


 


101
RTITSKIPKF ESLNLPPVLK DVALKKRGLV IFVGGTGSGK STSLASLIDY


 


151
RNENSFGHII TIEDPIEFVH EHKNCIITQR EVGVDTENWM AALKNTLRQA


 


201
PDVILIGEIR DRETMDYAIA FAETGHLCMA TLHANSTNQA LDRIINFFPE


 


251
ERREQLLTDL SLNLQAFISQ RLVPRDGGKG RVAAVEVLLN SPLISELIHN


 


301
GNIHEIKEVM KKSTTLGMQT FDQHLYQLYE KGDISLQEAL KNADSAHDLR


 


351
LAVQLRSRRA QSXSPDLXLL *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 272 shows 97.6% identity over a 370 aa overlap with a predicted ORF (ORF 272.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1113>:










a272.seq




1
ATGACCGCAA AGGAAGAACT GTTCGCATGG CTGCGCCATA TGAACAAAAA


 


51
CAAAGGTTCC GACCTGTTCG TGACGACCCA TTTCCCGCCC GCAATGAAGC


 


101
TGGACGGCAA AATCACCCGC ATCACGGACG AACCGCTGAC GGCGGAAAAA


 


151
TGTATGGAAA TCGCCTTTTC GATTATGAGT GCGAAGCAGG CGGAAGAATT


 


201
TTCATCGACC AACGAGTGCA ACTTCGCCAT CAGTCTGCCG GACACCAGCC


 


251
GCTTCCGCGT CAATGCGATG ATACAGCGCG GTGCGACGGC GTTGGTATTC


 


301
CGTGCGATTA CCAGCAAGAT TCCCAAGTTT GAAAGCCTGA ACCTGCCGCC


 


351
GGTCTTGAAG GATGTCGCGC TGAAAAAACG CGGGCTGGTT ATTTTTGTCG


 


401
GCGGCACCGG CTCGGGCAAA TCGACTTCGC TTGCCTCGCT TATCGACTAC


 


451
CGCAATGAAA ATTCGTTCGG ACACATCATC ACCATCGAAG ACCCGATCGA


 


501
GTTTGTCCAC GAACACAAAA ACTGCATCAT CACCCAGCGC GAGGTCGGCG


 


551
TGGATACGGA AAACTGGATG GCGGCGTTGA AAAACACGCT GCGTCAGGCA


 


601
CCGGATGTGA TTCTGATCGG CGAAATCCGC GACCGCGAAA CAATGGACTA


 


651
CGCCATTGCT TTTGCCGAAA CGGGGCATTT GTGTATGGCG ACGCTGCACG


 


701
CCAACAGCAC CAATCAGGCA CTCGACCGCA TCATCAACTT TTTCCCCGAG


 


751
GAGCGGCGCG AACAATTGCT GACGGATTTG TCGCTCAACC TTCAGGCATT


 


801
TATTTCGCAA CGCCTCGTTC CGCGAGACGG CGGCAAGGGC AGGGTGGCGG


 


851
CAGTCGAGGT GCTGCTCAAT TCGCCCCTGA TTTCGGAGTT GATTCACAAC


 


901
GGCAATATCC ATGAAATCAA AGAAGTGATG AAAAAATCCA CTACCCTGGG


 


951
TATGCAGACT TTCGACCAAC ACCTTTACCA ATTGTATGAA AAAGGCGAGA


 


1001
TTTCCTTGCA GGATGCCTTG AAAAATGCCG ATTCCGCACA CGATTTGCGT


 


1051
TTGGCGGTAC AGTTGCGCAG CCGCCAGGCG CAAAGTTCCG GTCCCGATTT


 


1101
GGAACTGCTC TGA






This corresponds to the amino acid sequence <SEQ ID 1114; ORF 272.a>:










a272.pep




1
MTAKEELFAW LRHMNKNKGS DLFVTTHFPP AMKLDGKITR ITDEPLTAEK


 


51
CMEIAFSIMS AKQAEEFSST NECNFAISLP DTSRFRVNAM IQRGATALVF


 


101
RAITSKIPKF ESLNLPPVLK DVALKKRGLV IFVGGTGSGK STSLASLIDY


 


151
RNENSFGHII TIEDPIEFVH EHKNCIITQR EVGVDTENWM AALKNTLRQA


 


201
PDVILIGEIR DRETMDYAIA FAETGHLCMA TLHANSTNQA LDRIINFFPE


 


251
ERREQLLTDL SLNLQAFISQ RLVPRDGGKG RVAAVEVLLN SPLISELIHN


 


301
GNIHEIKEVM KKSTTLGMQT FDQHLYQLYE KGEISLQDAL KNADSAHDLR


 


351
LAVQLRSRQA QSSGPDLELL *






m272/a272 97.6% identity in 370 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1115>:










g273.seq




1
atgagtcttc aggcggtatt tatatacccc ccaagccgta ccgcacaata


 


51
caacgaaaat caggaaaacg gcggtaaagc tcataaacag ggacaaagcg


 


101
gcaaacacac cgaccgccgt caggatatag gcgtattcga ggccggaact


 


151
ccattcaccg ttttcctgcc gtttcttgtc gcttttgaaa taaaggatga


 


201
tgccggcaag cagcgcggca gccgcgcccg acattggcat tgtgttcatt


 


251
gttgttcctt aacggttaaa aacccgcccg gccgtgcaac cgttttaagg


 


301
cgggaaattg caaaatttgt ttgcgggcgc gtgccgctga aatcaaggcg


 


351
gtttgagaag tgtttccnac gcgcccgccc tatgtgccga aatattattt


 


401
gtcgctcacc tgcaaaatcg ccaagaacgc gctttgcgga atttccacgt


 


451
tgcccacttg tttcatacgg cgtttgcctg ctttttgttt ttcaagcagt


 


501
tttttcttac gcgtaa






This corresponds to the amino acid sequence <SEQ ID 1116; ORF 273.ng>:










g273.pep




1
MSLQAVFIYP PSRTAQYNEN QENGGKAHKQ GQSGKHTDRR QDIGVFEAGT


 


51
PFTVFLPFLV AFEIKDDAGK QRGSRARHWH CVHCCSLTVK NPPGRATVLR


 


101
REIAKFVCGR VPLKSRRFEK CFXRARPMCR NIICRSPAKS PRTRFAEFPR


 


151
CPLVSYGVCL LFVFQAVFSY A*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1117>:










m273.seq




1
ATGAGTCTTC AGGCGGTATT TATATACCCm CCAAGCCGTA CCGCACAATA


 


51
CAACGAAAAT CAGGAAAACG GCGGTAAAGC TCAyAAACAG GGACAAAGCG


 


101
GCAAACACGC CGACCGCTGT CAGGATATAG GCGTATTCAA GGCCGGAACT


 


151
CCATTCCCCG TTTTCCTGCC GCTTCTTGTC GCTTTTGAAA TAAAGGATGA


 


201
TGCCGGCAAG CAGCGCGGCA GCCGCGCCCG ACATTAGCAT TGTGTTCATT


 


251
GTTGTTCCTT AATGCTTAAA AACCCGCCTG TCCGTGCAAC CGTTTTAAGG


 


301
CGGCAAATTG CAAAATTTGT TTGCGGGCGC GTGCCCCTGA AATCAGGGCG


 


351
GTTTGAGGGG TGTTCCCGAC GCGCCGCCCT GTGTGCCGGA GTTATTTGTC


 


401
GCTCACCTGC AAAATCGCCA AGAACGCGCT TTGCGGAATT TCCACATTGC


 


451
CCACTTGTTT CATACGGCGT TTACCTGCCT TTTGTkTwTC AAGCAGTTTT


 


501
TTCTTACGCG TAA






This corresponds to the amino acid sequence <SEQ ID 1118; ORF 273>:










m273.pep




1
MSLQAVFIYP PSRTAQYNEN QENGGKAHKQ GQSGKHADRC QDIGVFKAGT



 


51
PFPVFLPLLV AFEIKDDAGK QRGSRARH*H CVHCCSLMLK NPPVRATVLR


 


101
RQIAKFVCGR VPLKSGRFEG CSRRAALCAG VICRSPAKSP RTRFAEFPHC


 


151
PLVSYGVYLP FVXQAVFSYA *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 273 shows 86.0% identity over a 171 aa overlap with a predicted ORF (ORF 273.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1119>:










a273.seq




1
ATGAGTCTTC AGGCGGTATT TGTATACCCC CCAAGCCGTA CCGCACAATA



 


51
CAACGAAAAT CAGGAAAACG GCGGTAAAGC TCATAAACAG GGACAAAGCG


 


101
GCAAACACGC CGACCGCCGT CAGGATATAG GCGTATTCCA GACCGGAACT


 


151
CCATTCACCG TTTTCCTGCC GCTTTTTGTC GCTTTTGAAA TAAAGGATGA


 


201
TGCCGGCAAG CAGCGCGGCA GCCGCGCCCG ACATTAGCAT AATGTTCATT


 


251
GTTGTTCCTT AACGGTTAAA AACCCGCCCG TCCGTGCAAC CGTTTTTAAG


 


301
AGGCGGTAAA TCACAAAGTT TGTTGGCGGA CGTGCTCTCT TACAATCAGG


 


351
GCGGTTTAAG GGGCATGATG CACTGCCCCG TGTGCCGGAT ATTATTTGTC


 


401
GCTCACCTGC AAAATTGCCA AGAACGCGCT TTGCGGGATT TCCACATTGC


 


451
CCACTTGTTT CATACGGCGT TTGCCTGCTT TTTGTTTTTC AAGCAGTTTT


 


501
TTCTTACGCG TAA






This corresponds to the amino acid sequence <SEQ ID 1120; ORF 273.a>:










a273.pep




1
MSLQAVFVYP PSRTAQYNEN QENGGKAHKQ GQSGKHADRR QDIGVFQTGT



 


51
PFTVFLPLFV AFEIKDDAGK QRGSRARH*H NVHCCSLTVK NPPVRATVFK


 


101
RR*ITKFVGG RALLQSGRFK GHDALPRVPD IICRSPAKLP RTRFAGFPHC


 


151
PLVSYGVCLL FVFQAVFSYA *






m273/a273 80.1% identity in 171 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1121>:










g274.seq




1
ATGGCGGGGC CGATTTTTGT CGTCatCGCC AgcgTCGCTA TGTTTTTTGT



 


51
CGCGCAGCAG CACGCGACAG ATTTGGTTAC GGACGATTAT TATAAGGATG


 


101
GCAAGCATAT CGACATCCAG CTTCATCGGG ATGAAGAAGC CGTCAGACGG


 


151
CATATCGGGG TGCAGGTCCT CATTTCTCCC GATATGAATG CGGCAAAAGT


 


201
GTTTGTCGGc ggCgagtTTG ACGGCAAACA GCCTTTGAAC CTGCTGCTGA


 


251
TGCACCCGAC CCGCAAGGCG GACGATCAAA CCGTCGCCCT CAAGCCCGTC


 


301
GGCAGCGCGC AGAACGGCAG GGCGGAATAT GAGGCGGTgt tcaaAACCCT


 


351
TCCGCCGGCC AACCACTGGT ATGTGCGCGT GGAggacgCG GCAGGCGTGT


 


401
GGCGCGTCGA GAACAAATGG ATTACCAGCC AGGGCAATGC GGTCGATTTG


 


451
ACCCCGATGG ACAAACTTTT CAATAATGCA GGAAGCAAAT AA






This corresponds to the amino acid sequence <SEQ ID 1122; ORF 274.ng>:










g274.pep




1
MAGPIFVVIA SVAMFFVAQQ HATDLVTDDY YKDGKHIDIQ LHRDEEAVRR



 


51
HIGVQVLISP DMNAAKVFVG GEFDGKQPLN LLLMHPTRKA DDQTVALKPV


 


101
GSAQNGRAEY EAVFKTLPPA NHWYVRVEDA AGVWRVENKW ITSQGNAVDL


 


151
TPMDKLFNNA GSK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1123>:










m274.seq




1
ATGGCGGGGC CGATTTTTGT CGTCATCGCC AGCGTCGCTA TGTTTTTTGT



 


51
CGCGCAGCAG CACGCGACAG ATTTGGTTAC GGACGATTAT TATAAAGACG


 


101
GCAAACATAT CGACATCCAG CTTCATCGGG ATGAAGAAGC CGTCAGACGG


 


151
CATATCGGGG TGCAGGTTCT CATTTCCCCC GATATGAATG CGGCAAAAGT


 


201
GTTTGTCGGC GGCGAGTTTG ACGGCAAACA GCCTTTGAAC CTGCTGCTGA


 


251
TGCACCCGAC CCGCAAGGCG GACGATCAAA CCGTCGCCCT CAAGCCCGTC


 


301
GGCAGCGCGC AGAACGGCAG GGCGGAATAT GAGGCGGTGT TCAAAACCCT


 


351
TTCGCCGACC AACCACTGGT ATGTGCGCGT GGAGGACGCG GCAGGCGTGT


 


401
GGCGCGTCGA GAACAAATGG ATTACCAGCC AAGGCAATGC GGTCGATTTG


 


451
ACCCCGATGG ACAAGCTTTT CAATAATACT GAAAGCAAAT AA






This corresponds to the amino acid sequence <SEQ ID 1124; ORF 274>:










m274.pep




1
MAGPIFVVIA SVAMFFVAQQ HATDLVTDDY YKDGKHIDIQ LHRDEEAVRR



 


51
HIGVQVLISP DMNAAKVFVG GEFDGKQPLN LLLMHPTRKA DDQTVALKPV


 


101
GSAQNGRAEY EAVFKTLSPT NHWYVRVEDA AGVWRVENKW ITSQGNAVDL


 


151
TPMDKLFNNT ESK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 274 shows 97.5% identity over a 163 aa overlap with a predicted ORF (ORF 274.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1125>:










a274.seq




1
ATGGCGGGGC CGATTTTTGT CGTCATCGCC AGCGTCGCTA TGTTTTTTGT



 


51
CGCGCAGCAG CACGCGACAG ATTTGGTTAC GGACGATTAT TATAAAGACG


 


101
GCAAGCATAT CGACATCCAG CTTCATCGGG ATGAAGAAGC CGTCAGACGG


 


151
CATATCGGGG TGCAGGTTCT CATTTCCCCC GATATGAATG CGGCAAAAGT


 


201
GTTTGTCGGC GGCGAGTTTG ACGGCAAACA GCCTTTGAAC CTGCTGCTGA


 


251
TGCACCCGAC CCGCAAGGCG GACGATCAAA CCGTCGCCCT CAAGCCCGTC


 


301
GGCAGCGCGC AGAACGGCAG GGCGGAATAT GAGGCGGTGT TCAAAACCCT


 


351
TTCGCCGACC AACCACTGGT ATGTGCGCGT GGAGGACGCG GCAGGCGTGT


 


401
GGCGCGTCGA GAACAAATGG ATTACCAGCC AAGGCAATGC GGTCGATTTG


 


451
ACCCCGATGG ACAAACTTTT CAATAATACT GAAAGCAAAT AA






This corresponds to the amino acid sequence <SEQ ID 1126; ORF 274.a>:










a274.pep




1
MAGPIFVVIA SVAMFFVAQQ HATDLVTDDY YKDGKHIDIQ LHRDEEAVRR



 


51
HIGVQVLISP DMNAAKVFVG GEFDGKQPLN LLLMHPTRKA DDQTVALKPV


 


101
GSAQNGRAEY EAVFKTLSPT NHWYVRVEDA AGVWRVENKW ITSQGNAVDL


 


151
TPMDKLFNNT ESK*






m274/a274 100.0% identity in 163 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1127>:










g276.seq




1
atgattttgc cgccatccat gacgatgatg cggtcggcgg attcgacggt



 


51
ggtcaggcgg tgggcgacga tgatgccggt gcggttttcc atcaggcgtt


 


101
cgagcgcttg ttggacgagg cgttcggatt cgttgtccaa tgcgctggtg


 


151
gcttcgtcca ataataatat cggcgcgtct ttcaaaatgg cgcgggcgat


 


201
ggcgacgcgt tgccgctgtc cgccggataa gttgctgccg ttcgatccga


 


251
tgggctggtg cagtccgagc ggggatgcgt cgatcaggct ttgcaggttg


 


301
gcggcttgga gggcggacag gacttcggct tcgcccgcgt cgggacggct


 


351
gtatcggacg ttttcaaaca gggtgtcgtc aaacaggaat acgtcttggg


 


401
agacgagggc gaattgggcg cgcaggcagt cgagtttgat gtcggcgatg


 


451
tcgataccgt ctatgcagat gttgccggca gacggttcga caaagcgggg


 


501
cagaaggttg acgacggtgg atttgccgct gccggaacgt ccgaccaggg


 


551
cgacgcgttc gccttgtctg atgtcgaggt tgaagttgtc gagggctttg


 


601
atgccgtctg aacggtattc gacatcgacg ttgcggaagc tgatgcgccc


 


651
ttcgacacgc tgcggcgcga gcgtgccttt gtcctgttcg ggcggggtgt


 


701
cgagaaatgc acatacgccg tcggcggcga ggaacatcgt ctgcataggg


 


751
atgctgatgt tggcaaggct tttgatgggg gcgtacattt gcagcatcgc


 


801
gacgatgaat gccataaatt cgccgatggt ggtgtag






This corresponds to the amino acid sequence <SEQ ID 1128; ORF 276.ng>:










g276.pep




1
MILPPSMTMM RSADSTVVRR WATMMPVRFS IRRSSACWTR RSDSLSNALV



 


51
ASSNNNIGAS FKMARAMATR CRCPPDKLLP FDPMGWCSPS GDASIRLCRL


 


101
AAWRADRTSA SPASGRLYRT FSNRVSSNRN TSWETRANWA RRQSSLMSAM


 


151
SIPSMQMLPA DGSTKRGRRL TTVDLPLPER PTRATRSPCL MSRLKLSRAL


 


201
MPSERYSTST LRKLMRPSTR CGASVPLSCS GGVSRNAHTP SAARNIVCIG


 


251
MLMLARLLMG AYICSIATMN AINSPMVV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1129>:










m276.seq




1
ATGATTTTGC CGTCGTCCAT CACGATGATG CGGTCGGCCC CTTCGATGGT



 


51
GGTCAGGCGG TGGGCGACGA TGATGCCGGT GCGGTTTTCC ATCAGGCGTT


 


101
CGAGCGCCTG TTGGACGAGG CGTTCGGATT CGTTGTCTAA TGCGCTGGTG


 


151
GCTTCGTCCA ATAATAATAT CGGCGCGTCT TTCAAAATGG CGCGGGCAAT


 


201
GGCGACGCGT TGCCGCTGTC CGCCGGATAA GTTGCTGCCG TTCGATCCGA


 


251
TGGGCTGGTG CAGTCCGAGC GGGGAGCTGT CAATCAGGCT TTGCAGGTTG


 


301
GCGGTTTGGA GGGCGAACAG GACTTCGGCT TCGCCCGCGT CGGGACGGCT


 


351
GTATCGGACG TTTTCAAACA GGGTGTCGTC AAACAGGAAT ACGTCTTGGG


 


401
AGACGAGGGC GAATTGGGCG CGCAGGCAGT CGAGTTTGAT GTCGGCGATG


 


451
TCGATACCGT CTATGCAGAT GTTGCCGGCA GACGGTTCGA CAAAGCGGGG


 


501
CAGCAGGTTG ACGACGGTGG ATTTGCCGCT GCCGGAACGT CCGACCAGGG


 


551
CGACGCGTTC GCCTTGTCTG ATGTCGAGGT TGAAGTTGTC GAGGGCTTTG


 


601
ATGCCGTCTG AACGGTATTC GACATCGACG TTGCGGAAGC TGATGCGCCC


 


651
TTCGACACGC TGCGGTGCGA GCGTGCCCTT GTCCTGTTCG GGCGGGGTGT


 


701
CGAGAAATGC ACATACACCG TCGGCGGCGA GGAACATCGT CTGCATAGGG


 


751
ATGCTGATGT TGGCAAGGCT TTTGATGGGG GCGTACATTT GCAGCATCGC


 


801
GACGATGAAT GCCATAAATT CGCCGATGGT GGTGTAG






This corresponds to the amino acid sequence <SEQ ID 1130; ORF 276>:










m276.pep




1
MILPSSITMM RSAPSMVVRR WATMMPVRFS IRRSSACWTR RSDSLSNALV



 


51
ASSNNNIGAS FKMARAMATR CRCPPDKLLP FDPMGWCSPS GELSIRLCRL


 


101
AVWRANRTSA SPASGRLYRT FSNRVSSNRN TSWETRANWA RRQSSLMSAM


 


151
SIPSMQMLPA DGSTKRGSRL TTVDLPLPER PTRATRSPCL MSRLKLSRAL


 


201
MPSERYSTST LRKLMRPSTR CGASVPLSCS GGVSRNAHTP SAARNIVCIG


 


251
MLMLARLLMG AYICSIATMN AINSPMVV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 276 shows 96.8% identity over a 278 aa overlap with a predicted ORF (ORF 276.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1131>:










a276.seq




1
ATGATTTTGC CGTCGTCCAT TACGATGATG CGGTCGGCCC CTTCGATGGT



 


51
GGTCAGGCGG TGGGCGACGA TGATGCCGGT GCGGTTTTCC ATCAGGCGTT


 


101
CGAGCGCCTG TTGGACGAGG CGTTCGGATT CGTTGTCCAA TGCGCTGGTG


 


151
GCTTCGTCCA ATAATAATAT CGGCGCGTCT TTCAAAATGG CGCGGGCAAT


 


201
GGCAACGCGT TGCCGCTGTC CGCCGGATAA GTTGCTGCCG TTCGATCCGA


 


251
TGGGCTGGTG CAGTCCGAGC GGTGATGCGT CGATCAGGCT TTGCAGGTTA


 


301
GCGGCTTGGA GGGCGGATAG GACTTCGGCT TCGCCCGCGT CGGGACGGCT


 


351
ATATCGGACG TTTTCAAACA GGGTGTCGTC AAACAGGAAT ACGTCTTGGG


 


401
AGACGAGGGC AAATTGGGCG CGCAGGCAGT CGAGTTTGAT GTCGGCGATG


 


451
TCGATACCGT CTATGCAGAT GTTGCCGGCA GACGGTTCGA CAAAGCGGGG


 


501
CAGCAGGTTG ACGACGGTGG ATTTGCCGCT GCCGGAACGT CCGACCAGGG


 


551
CGACGCGTTC GCCTTGTCTG ATGTCGAGGT TGAAGCCGTC GAGGGCTTTG


 


601
ATGCCGTCCG AACGGTATTC GACATCGACG TTGCGGAAGC TGATGCGCCC


 


651
TTCGACACGC TGCGGTGCGA GCGTGCCTTT GTCCTGTTCG GGCGGGGTGT


 


701
CGAGAAATGC ACATACGCCG TCGGCGGCGA GGAACATCGT CTGCATAGGG


 


751
ATGCTAATGT TGGCAAGGCT TTTGATGGGG GCGTACATTT GCAGCATCGC


 


801
GACGATGAAT GCCATAAATT CGCCGATGGT GGTGTAG






This corresponds to the amino acid sequence <SEQ ID 1132; ORF 276.a>:










a276.pep




1
MILPSSITMM RSAPSMVVRR WATMMPVRFS IRRSSACWTR RSDSLSNALV



 


51
ASSNNNIGAS FKMARAMATR CRCPPDKLLP FDPMGWCSPS GDASIRLCRL


 


101
AAWRADRTSA SPASGRLYRT FSNRVSSNRN TSWETRANWA RRQSSLMSAM


 


151
SIPSMQMLPA DGSTKRGSRL TTVDLPLPER PTRATRSPCL MSRLKPSRAL


 


201
MPSERYSTST LRKLMRPSTR CGASVPLSCS GGVSRNAHTP SAARNIVCIG


 


251
MLMLARLLMG AYICSIATMN AINSPMVV*






m276/a276 98.2% identity in 278 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1133>:









g277.seq (partial)










1
..atggtacacg tcgccgtagc ttacggtatt gccgtccggc gtttttgccc



 


51
  aaacgaggtc atagacgttt tccacgcctt gcaggtacat cgccaagcgt


 


101
  tcgatgccgt aggtaatttc gccgagtacg ggcgtgcaat cgataccgcc


 


151
  gacttgttgg aaataggtaa actgggttac ttccatgccg ttgagccaga


 


201
  cttcccagcc caaaccccac gcaccgaggg tggggttttc ccagtcgtct


 


251
  tcgacaaagc ggatgtcgtg gactttggga tcgatgccca attcgcgcag


 


301
  ggagtcgaga tagaggtctt ggatattggc gggggcgggt ttgagggcga


 


351
  cttggaattg gtaatagtgt tgcaggcggt tggggttgtc gccgtagcgg


 


401
  ccgtctttgg ggcggcggct gggttggacg taggcggcaa accaaggctc


 


451
  ggggccgagc gcgcgcaggc aggtggcggg atgggatgtg ccggcaccga


 


501
  cttccatgtc gaagggttgg atgacggtgc agcctttgtc tgcccagaag


 


551
  gtttgcagtt tgaagatgat ttgttggaag gtaagcatgg cttattgttc


 


601
  gataaaataa aggttttatt ttactgtttc catagccgct tgaatagatt


 


651
  tatctcgaag acagcctga






This corresponds to the amino acid sequence <SEQ ID 1134; ORF 277.ng>:









g277.pep (partial)










1
..MVHVAVAYGI AVRRFCPNEV IDVFHALQVH RQAFDAVGNF AEYGRAIDTA



 


51
  DLLEIGKLGY FHAVEPDFPA QTPRTEGGVF PVVFDKADVV DFGIDAQFAQ


 


101
  GVEIEVLDIG GGGFEGDLEL VIVLQAVGVV AVAAVFGAAA GLDVGGKPRL


 


151
  GAERAQAGGG MGCAGTDFHV EGLDDGAAFV CPEGLQFEDD LLEGKHGLLF


 


201
  DKIKVLFYCF HSRLNRFISK TA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1135>:










m277.seq




1
ATGCCCCGCT TTGAGGACAA GCTCGTAGGC AGGCAGGGCG AGGGCGGCGT


 


51
TTTCTTCGGC AAGCAGGCGT TTGGCTTGCG CTTCGTAGTC GTTGAACTGG


 


101
CGCAGCAGCC AGTCGGCATC GCTGTATTCG AAGTTGTAGG TGGATTGCTC


 


151
GACTTCGTTT TGGTGGTACA CGTCGCCGTA GGTGACGGTG TTGCCGTCGA


 


201
GCGTTTTTGC CCAAACGAGG TCGTAGACGT TTTCTACACC TTGCAAGTAC


 


251
ATCGCCAAGC GTTCGATGCC GTAGGTGATT TCGCCGAGTA CGGGCGTGCA


 


301
GTCGATGCCG CCGACTTGTT GGAAATAGGT AAACTGGGTT ACTTCCATGC


 


351
CGTTGAGCCA GACTTCCCAG CCCAAACCCC ACGCGCCGAG GGTGGGGTTT


 


401
TCCCAGTCGT CTTCGACAAA GCGGATGTCG TGGACTTTGG GATCGATGCC


 


451
CAATTCGCGC AGAGAGTCGA GATAGAGGTC TTGGATATTG GCGGGAGCGG


 


501
GCTTGAGGGC GACTTGGAAT TGGTAATAGT GTTGCAGGCG GTTGGGGTTG


 


551
TCGCCGTAGC GGCCGTCTTT GGGGCGGCGG CTGGGTTGGA CGTAGGCGGC


 


601
AAACCAAGGC TCGGGGCCGA GTGCGCGCAG GCAGGTGGCG GGATGGGATG


 


651
TGCCGGCACC GACTTCCATG TCGAAGGGTT GGATGACGGT GCAGCCTTTG


 


701
TCTGCCCAGA ATGTTTGCAG TTTGAAGATG ATTTGTTGGA AGGTAAGCAT


 


751
GGCTTATGA






This corresponds to the amino acid sequence <SEQ ID 1136; ORF 277>:










m277.pep




1
MPRFEDKLVG RQGEGGVFFG KQAFGLRFVV VELAQQPVGI AVFEVVGGLL


 


51
DFVLVVHVAV GDGVAVERFC PNEVVDVFYT LQVHRQAFDA VGDFAEYGRA


 


101
VDAADLLEIG KLGYFHAVEP DFPAQTPRAE GGVFPVVFDK ADVVDFGIDA


 


151
QFAQRVEIEV LDIGGSGLEG DLELVIVLQA VGVVAVAAVF GAAAGLDVGG


 


201
KPRLGAECAQ AGGGMGCAGT DFHVEGLDDG AAFVCPECLQ FEDDLLEGKH


 


251
GL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 277 shows 90.0% identity over a 221 aa overlap with a predicted ORF (ORF 277.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1137>:










a277.seq




1
ATGCCCCGCT TTGAGGACAA GCTCGTAGGC AGGCAGGGCG AGGGCGGCGT


 


51
TTTCTTCGGC AAGCAGGCGT TTGGCTTGCG CTTCGTAGTC GTTGAACTGG


 


101
CGCAGCAGCC AATCGGCATC GCTGTATTCG AAGTTGTAGG TGGATTGTTC


 


151
GACTTCGTTT TGGTGGTACA CGTCGCCGTA AGTTACTGTA TTACCGTCCA


 


201
GCGTTTTTGC CCAAACGAGG TCATAGACGT TTTCCACGCC TTGCAGGTAC


 


251
ATCGCCAAGC GTTCGATGCC GTAGGTGATT TCGCCGAGTA CGGGGGTGCA


 


301
GTCGATGCCG CCGACTTGTT GGAAATAGGT GAACTGGGTT ACTTCCATAC


 


351
CGTTGAGCCA GACTTCCCAG CCCAAACCCC ACGCGCCGAG GGTGGGGTTT


 


401
TCCCAGTCGT CTTCGACAAA GCGGATGTCG TGCACTTTGG GGTCGATGCC


 


451
CAATTCGCGC AGGGAGTCGA GATAGAGGTC TTGGATATTG GCGGGAGCGG


 


501
GCTTGAGGGC GACTTGGAAT TGGTAATAGT GTTGCAGGCG GTTGGGGTTG


 


551
TCGCCGTAGC GACCGTCTTT GGGGCGGCGG CTGGGTTGGA CGTAGGCGGC


 


601
AAACCAAGGC TCGGGGCCGA GTGCGCGCAG ACAGGTGGCG GGATGGGATG


 


651
TGCCGGCACC GACTTCCATG TCGAAGGGTT GGATGACGGT GCAGCCTTTG


 


701
TCTGCCCAGA ATGTTTGCAG TTTGAAGATG ATTTGTTGGA AGGTAAGCAT


 


751
GGCTTATGA






This corresponds to the amino acid sequence <SEQ ID 1138; ORF 277.a>:










a277.pep




1
MPRFEDKLVG RQGEGGVFFG KQAFGLRFVV VELAQQPIGI AVFEVVGGLF


 


51
DFVLVVHVAV SYCITVQRFC PNEVIDVFHA LQVHRQAFDA VGDFAEYGGA


 


101
VDAADLLEIG ELGYFHTVEP DFPAQTPRAE GGVFPVVFDK ADVVHFGVDA


 


151
QFAQGVEIEV LDIGGSGLEG DLELVIVLQA VGVVAVATVF GAAAGLDVGG


 


201
KPRLGAECAQ TGGGMGCAGT DFHVEGLDDG AAFVCPECLQ FEDDLLEGKH


 


251
GL*






m277/a277 92.5% identity in 252 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1139>:









g278.seq (partial)










1
ttgcgtgcaa tcacgcccgg tgcgattttt tcgacagggg cggtcaaagt



 


51
tgtattaatc ggacctttgc cgtcgatagg ccgacccaat gcatcgacga


 


101
cgcgtccgac caattcgcgt ccgaccggca cttctaaaat acggccggta


 


151
caggtaaccg tgtcgccttc tttaatatgt tcgtactcgc ccaacactac


 


201
ggcaccgacg gagtcgcgct ccaggttcat cgccaagcct aaagtgttac


 


251
ccgggaattc gagcatctca ccttgcattg catctgacaa accatggatg


 


301
cgaacgatac cgtcagttac cgaaatcacc gtaccacggg tactcacttc


 


351
ggcatttaca gacagatttt cgatcttggc tttaatcaga tcgctaattt


 


401
cagcaggatt aagctgcatg aaaactctcc taattcgtca tagtcgtgta


 


451
caaagcactc agtttgcctt gtacagacaa atccaaaacc tgatcaccca


 


501
cttcaacttt ta...






This corresponds to the amino acid sequence <SEQ ID 1140; ORF 278.ng>:









g278.pep (partial)










1
LRAITPGAIF STGAVKVVLI GPLPSIGRPN ASTTRPTNSR PTGTSKIRPV



 


51
QVTVSPSLIC SYSPNTTAPT ESRSRFIAKP KVLPGNSSIS PCIASDKPWM


 


101
RTIPSVTEIT VPRVLTSAFT DRFSILALIR SLISAGLSCM KTLLIRHSRV


 


151
QSTQFALYRQ IQNLITHFNF....






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1141>:










m278.seq..




1
TTGCGCGCAA TCACGCCCGG TGCGATTTTT TCGATAGGGG CGGTCAAAGT


 


51
TGTATTAATC GGGCCTTTGC CGTCGATAGG CCGACCCAAT GCATCAACGA


 


101
CGCGTCCGAC CAGTTCGCGT CCGACCGGCA CTTCCAAGAT ACGACCGGTA


 


151
CAGGTAACCG TGTCGCCTTC TTTAATGTGT TCGTACTCGC CCAACACTAC


 


201
GGCGCCGACG GAGTCGCGCT CCAGGTTCAT CGCCAAGCCG AAAGTGTTAC


 


251
CCGGGAATTC GAGCATCTCA CCTTGCATTG CATCTGACAA ACCATGGATG


 


301
CGAACGATAC CGTCAGTTAC CGAAATTACC GTACCACAGG TACGCACTTC


 


351
GGCATTTACA GACAGATTTT CGATCTTGGC TTTAATCAAA TCGCTAATTT


 


401
CAGCAGGATT AAGCTGCATG AAAACTCTCC TAATTCGTCA TAGTCGTGTA


 


451
CAAGGCACTC AATTTGCCTT GTACAGACAA ATCCAAAACC TGATCACCCA


 


501
CTTCAACTTT TATGCCGCCA ATCAGCTCCG GTTCGATTTC GACAGAGATT


 


551
TTCAGCTCGC TGTCGAAACG CTTATTCAGC ATTTGCACCA ACTCGCCGAC


 


601
CTGTTTGTCG GTCAACGGAT AGGCACTGTA AATGACGGCA GATTTGATAT


 


651
GGTTGAATGA






This corresponds to the amino acid sequence <SEQ ID 1142; ORF 278>:










m278.pep




1
LRAITPGAIF SIGAVKVVLI GPLPSIGRPN ASTTRPTSSR PTGTSKIRPV


 


51
QVTVSPSLMC SYSPNTTAPT ESRSRFIAKP KVLPGNSSIS PCIASDKPWM


 


101
RTIPSVTEIT VPQVRTSAFT DRFSILALIK SLISAGLSCM KTLLIRHSRV


 


151
QGTQFALYRQ IQNLITHFNF YAANQLRFDF DRDFQLAVET LIQHLHQLAD


 


201
LFVGQRIGTV NDGRFDMVE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 278 shows 95.9% identity over a 170 aa overlap with a predicted ORF (ORF 278.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1143>:










a278.seq




1
TTGCGCGCAA TCACGCCCGG TGCGATTTTT TCGATAGGGG CGGTCAAAGT


 


51
TGTATTAATC GGGCCTTTGC CGTCGATAGG CCGACCCAAT GCATCAACGA


 


101
CGCGTCCGAC CAGTTCGCGT CCGACCGGCA CTTCCAAGAT ACGACCGGTA


 


151
CAGGTAACCG TGTCGCCTTC TTTAATATGT TCGTGCTCGC CCAACACTAC


 


201
GGCGCCGACG GAGTCGCGCT CCAGGTTCAT CGCCAAGCCG AAAGTGTTAC


 


251
CCGGGAATTC GAGCATCTCA CCTTGCATTG CATCTGACAA ACCATGGATG


 


301
CGAACGATAC CGTCAGTTAC CGAAATCACC GTACCACGGG TACGCACTTC


 


351
GGCATTTACA GACAGATTTT CGATCTTGGC TTTAATCAAA TCGCTAATTT


 


401
CAGCAGGATT AAGCTGCATG AAAACTCTCC TAATTCGTCA TAGTCGTGTA


 


451
CAAGGCACTC AATTTGCCTT GTACAGACAA ATCCAAAACC TGATCACCCA


 


501
CTTCAACTTT TATGCCGCCA ATCAGCTCCG GTTCGATTTC GACAGAGATT


 


551
TTCAGCTCGC TGTCGAAACG CTTATTCAGC ATTTGCGCCA ACTCGCCGAC


 


601
CTGTTTGTCG GTCAACGGAT AGGCACTGTA AATGACGGCA GATTTGATAT


 


651
GGTTGAATGA






This corresponds to the amino acid sequence <SEQ ID 1144; ORF 278.a>:










a278.pep




1
LRAITPGAIF SIGAVKVVLI GPLPSIGRPN ASTTRPTSSR PTGTSKIRPV


 


51
QVTVSPSLIC SCSPNTTAPT ESRSRFIAKP KVLPGNSSIS PCIASDKPWM


 


101
RTIPSVTEIT VPRVRTSAFT DRFSILALIK SLISAGLSCM KTLLIRHSRV


 


151
QGTQFALYRQ IQNLITHFNF YAANQLRFDF DRDFQLAVET LIQHLRQLAD


 


201
LFVGQRIGTV NDGRFDMVE*






m278/a278 98.2% identity in 219 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1145>:










g279.seq




1
atgacgcgga tttgcggctg cttgatttca acggttttga gtgtttcggc


 


51
aagtttgtcg gcggcgggtt tcatcaggct gcaatgggaa ggaacggata


 


101
ccggcagcgg cagggcgcgt ttggctccgg cttctttggc ggcagccatg


 


151
gtgcgtccga cggcggcggc gttgcctgca atcacgactt gtccgggcga


 


201
gttgaagttg acggcttcga ccacttcgcc ctgtgcggat tcggcacaaa


 


251
tctgcctgac ctgttcatct tccaaaccca aaatggccgc cattgcgcct


 


301
acgccttgcg gtacggcgga ctgcatcagt tcggcgcgca ggcggacgag


 


351
tttgacggca tcggcaaaat ccaatgcttc ggcggcgaca agcgcggtgt


 


401
attcgccgag gctgtgtccg gcaacggcgg caggcgtttt gccgcccact


 


451
tccaaatag






This corresponds to the amino acid sequence <SEQ ID 1146; ORF 279.ng>:










g279.pep




1
MTRICGCLIS TVLSVSASLS AAGFIRLQWE GTDTGSGRAR LAPASLAAAM


 


51
VRPTAAALPA ITTCPGELKL TASTTSPCAD SAQICLTCSS SKPKMAAIAP


 


101
TPCGTADCIS SARRRTSLTA SAKSNASAAT SAVYSPRLCP ATAAGVLPPT


 


151
SK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1147>:










m279.seq




1
ATAACGCGGA TTTGCGGCTG CTTGATTTCA ACGGTTTTCA GGGCTTCGGC


 


51
AAGTTTGTCG GCGGCGGGTT TCATCAGGCT GCAATGGGAA GGTACGGACA


 


101
CGGGCAGCGG CAGGGCGCGT TTGGCACCGG CTTCTTTGGC GGCAGCCATG


 


151
GCGCGTCCGA CGGCGGCGGC GTTGCCTGCA ATCACGATTT GTCCGGGTGA


 


201
GTTGAAGTTG ACGGCTTCGA CCACTTCGCT TTGGGCGGCT TCGGCACAAA


 


251
TGGCTTTAAC CTGCTCATCT TCCAAGCCGA GAATCGCCGC CATTGCGCCC


 


301
ACGCCTTGCG GTACGGCGGA CTGCATCAGT TCGGCGCGCA GGCGCACGAG


 


351
TTTGACCGCG TCGGCAAAAT TCAATGCGCC GGCGGCAACG AGTGCGGTGT


 


401
ATTCGCCGAG GCTGTGTCCG GCAACGGCGG CAGGCGTTTT GCCGCCCGCT


 


451
TCTAAATAG






This corresponds to the amino acid sequence <SEQ ID 1148; ORF 279>:










m279.pep




1
ITRICGCLIS TVFRASASLS AAGFIRLQWE GTDTGSGRAR LAPASLAAAM


 


51
ARPTAAALPA ITICPGELKL TASTTSLWAA SAQMALTCSS SKPRIAAIAP


 


101
TPCGTADCIS SARRRTSLTA SAKFNAPAAT SAVYSPRLCP ATAAGVLPPA


 


151
SK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 279 shows 89.5% identity over a 152 aa overlap with a predicted ORF (ORF 279.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1149>:










a279.seq




1
ATGACNCNGA TTTGCGGCTG CTTGATTTCA ACGGTTTNNA GGGCTTCGGC


 


51
GAGTTTGTCG GCGGCGGGTT TCATGAGGCT GCAATGGGAA GGTACNGACA


 


101
CNGGCAGCGG CAGGGCGCGT TTGGCGCCGG CTTCTTTGGC GGCAAGCATA


 


151
GCGCGCTCGA CGGCGGCGGC ATTGCCTGCA ATCACGACTT GTCCGGGCGA


 


201
GTTGAAGTTG ACGGCTTCAA CCACTTCATC CTGTGCGGAT TCGGCGCAAA


 


251
TTTGTTTTAC CTGTTCATCT TCCAAGCCGA GAATCGCCGC CATTGCGCCC


 


301
ACGCCTTGCG GTACGGCGGA CTGCATCAGT TCGGCGCGCA NGCGCACGAG


 


351
TTTGACCGCG TCGGCAAAAT CCAATGCGCC GGCGGCAACN AGTGCGGTGT


 


401
ATTCGCCGAN GCTGTGTCCG GCAACGGCGG CAGGCGTTTT GCCGCCCGCT


 


451
TCCGAATAG






This corresponds to the amino acid sequence <SEQ ID 1150; ORF 279.a>:










a279.pep




1
MTXICGCLIS TVXRASASLS AAGFMRLQWE GTDTGSGRAR LAPASLAASI


 


51
ARSTAAALPA ITTCPGELKL TASTTSSCAD SAQICFTCSS SKPRIAAIAP


 


101
TPCGTADCIS SARXRTSLTA SAKSNAPAAT SAVYSPXLCP ATAAGVLPPA


 


151
SE*






m279/a279 88.2% identity in 152 aa overlap





Expression of ORF 279
The primer described in Table 1 for ORF 279 was used to locate and clone ORF 279. ORF 279 was cloned in pET and pGex vectors and expressed in E. coli as above-described. The products of protein expression and purification were analyzed by SDS-PAGE. FIG. 2A shows the results of affinity purification and FIG. 2B shows the expression in E. coli. Purified GST-fusion protein was used to immunize mice whose sera were used for ELISA (positive result), FACS analysis (FIG. 2C), western blot (FIG. 2D). These experiments confirm that 279 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 279 are provided in FIG. 6. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 279 and the amino acid sequence encoded thereby is provided herein.
The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1151>:









g280.seq




1
atgaaacacc tcaaacttac ccttattgcc gcattgctgg ccaccgccgc


 


51
aactgccgca ccccttccgg ttgtaaccag tttcagcatt ttaggcgacg


 


101
tagccaaaca aatcggcggt gagcgcgtag ccgtacaaag cctcgtcgga


 


151
gccaaccaag atactcatgc ctatcacatg accagtggcg acattaaaaa


 


201
aatccgcagt gcaaaactcg tcctgctcaa cggcttggga cttgaagccg


 


251
ccgacatcca acgcgccgtc aaacagagca aagtatccta tgccgaagcg


 


301
accaaaggca tccaacccct caaagccgaa gaagaaggcg gacaccatca


 


351
cgaccaccat cacgaccacg atcatgacca cgaaggacac caccacgacc


 


401
acggcgaata tgacccccac gtctggaacg accctgttct tatgtccgac


 


451
tatgcccaaa acgtcgctga aaccctgata aaggccgatc ccgaaggcaa


 


501
agtttattat caacaacgct tgggcaacta ccaaatgcag cttaaaaaac


 


551
tgcacagcga cgcacaagcc gcatttaatg ccgtccctgc cgccaaacgc


 


601
aaagtcctga ccgggcacga cgcattttcc tacatgggca accgctacaa


 


651
catcagcttc atcgccccgc aaggcgtgag cagcgaagcc gagccgtccg


 


701
ccaaacaagt cgccgccatc atccggcaaa tcaaacgcga aggcatcaaa


 


751
gccgtattta ccgaaaatat caaagacacc cgcatggttg accgcatcgc


 


801
caaagaaacc ggcgtcaacg tcagcggcaa actgtattcc gacgcactcg


 


851
gcaacgcgcc cgcagacacc tacatcggca tgtaccgcca caacgtcgaa


 


901
gccttgacca acgcgatgaa gcaataa






This corresponds to the amino acid sequence <SEQ ID 1152; ORF 280.ng>:










g280.pep




1
MKHLKLTLIA ALLATAATAA PLPVVTSFSI LGDVAKQIGG ERVAVQSLVG


 


51
ANQDTHAYHM TSGDIKKIRS AKLVLLNGLG LEAADIQRAV KQSKVSYAEA


 


101
TKGIQPLKAE EEGGHHHDHH HDHDHDHEGH HHDHGEYDPH VWNDPVLMSD


 


151
YAQNVAETLI KADPEGKVYY QQRLGNYQMQ LKKLHSDAQA AFNAVPAAKR


 


201
KVLTGHDAFS YMGNRYNISF IAPQGVSSEA EPSAKQVAAI IRQIKREGIK


 


251
AVFTENIKDT RMVDRIAKET GVNVSGKLYS DALGNAPADT YIGMYRHNVE


 


301
ALTNAMKQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1153>:










m280.seq




1
ATGAAACACC TCAAACTCAC CCTTATTGCC GCATTGCTGA CCGCCTCCGC


 


51
AACTGCCGCC CCCCTGCCGG TTGTAACCAG CTTCAGCATT TTAGGCGACG


 


101
TAGCCAAACA AATCGGCGGA GAGCGCGTAT CCATACAAAG TTTGGTCGGA


 


151
GCCAACCAAG ATACGCACGC CTATCATATG ACCAGTGGCG ACATTAAAAA


 


201
AATCCGCAGT GCAAAACTCG TCCTGCTCAA CGGCTTAGGA CTTGAAGCTG


 


251
CCGATGTGCA ACGCGCCGTC AAACAAAGCA AAGTATCCTA TACCGAAGCG


 


301
ACCAAAGGCA TCCAACCCCT CAAAGCCGAA GAAGAAGGCG GACACCATCA


 


351
CGACCACGAT CATGACCACG AAGGACACCA CCATGACCAC GGCGAATATG


 


401
ACCCGCACGT CTGGAACGAC CCCGTCCTTA TGTCCGCCTA TGCCCAAAAC


 


451
GTTGCCAAAG CCCTGATAAA GGCCGATCCC GAAGGCAAAG TTTATTATCA


 


501
ACAACGCTTG GGCAACTACC AAATGCAGCT CAAAAAACTG CACAGCGACG


 


551
CACAAGCCGC ATTTAATGCC GTCCCTGCTG CCAAACGCAA AGTCCTGACC


 


601
GGGCACGATG CCTTTTCCTA TATGGGCAAA CGTTACCATA TCGAATTCAT


 


651
CGCCCCGCAA GGCGTGAGCA GCGAAGCCGA GCCTTCGGCC AAACAAGTCG


 


701
CCGCCATCAT CCGACAAATC AAACGCGAAG GCATCAAAGC CGTCTTTACC


 


751
GAAAACATCA AGGACACCCG TATGGTTGAC CGTATCGCCA AAGAAACCGG


 


801
TGTCAACGTC AGCGGCAAAC TGTATTCCGA CGCACTCGGC AACGCGCCCG


 


851
CAGACACCTA CATCGGAATG TACCGCCACA ACATCAAAGC CTTGACCAAC


 


901
GCGATGAAGC AATAA






This corresponds to the amino acid sequence <SEQ ID 1154; ORF 280>:










m280.pep




1
MKHLKLTLIA ALLTASATAA PLPVVTSFSI LGDVAKQIGG ERVSIQSLVG


 


51
ANQDTHAYHM TSGDIKKIRS AKLVLLNGLG LEAADVQRAV KQSKVSYTEA


 


101
TKGIQPLKAE EEGGHHHDHD HDHEGHHHDH GEYDPHVWND PVLMSAYAQN


 


151
VAKALIKADP EGKVYYQQRL GNYQMQLKKL HSDAQAAFNA VPAAKRKVLT


 


201
GHDAFSYMGK RYHIEFIAPQ GVSSEAEPSA KQVAAIIRQI KREGIKAVFT


 


251
ENIKDTRMVD RIAKETGVNV SGKLYSDALG NAPADTYIGM YRHNIKALTN


 


301
AMKQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 280 shows 93.8% identity over a 308 aa overlap with a predicted ORF (ORF 280.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1155>:










a280.seq




1
ATGAAACACC CCAAACTCAC CCTTATCGCC GCATTGCTGA CCACTGCCGC


 


51
AACTGCCGCC CCCCTGCCGG TTGTAACCAG CTTCAGCATT TTAGGCGACG


 


101
TAGCCAAACA AATCGGCGGA GAGCGCGTAT CCATACAAAG TTTGGTCGGA


 


151
GCCAACCAAG ATACGCACGC CTATCATATG ACCAGCGGCG ACATTAAAAA


 


201
AATCCGCAGT GCAAAACTCG TCCTGATTAA CGGCTTAGGA CTTGAAGCTG


 


251
CCGACATCCA ACGTGCCGTC AAACAGAGCA AAGTATCCTA TGCCGAAGCG


 


301
ACCAAAGGCA TCCAACCCCT CAAAGCCGAA GAAGAAGGCG GACACCATCA


 


351
CGACCACGAT CATGACCACG ACCATGACCA CGAAGGACAC CACCACGACC


 


401
ACGGCGAATA TGACCCCCAC GTCTGGAACG ACCCCGTCCT TATGTCCGCC


 


451
TATGCCCAAA ACGTCGCCGA AGCCCTGATA AAGGCCGACC CCGAAGGCAA


 


501
AGTTTATTAT CAACAACGCT TGGGCAACTA CCAAATGCAG CTCAAAAAAC


 


551
TGCACAGTGA CGCACAAGCC GCATTTAATG CCGTCCCTGC CGCCAAACGC


 


601
AAAGTCCTGA CCGGGCACGA TGCCTTTTCC TATATGGGCA AACGTTACCA


 


651
TATCGAATTC ATCGCCCCAC AAGGTGTGAG CAGCGAAGCC GAGCCTTCAG


 


701
CCAAACAAGT CGCCGCCATC ATCCGACAAA TCAAACGCGA AGGCATCAAA


 


751
GCCGTATTTA CCGAAAATAT CAAAGACACC CGCATGGTTG ACCGCATCGC


 


801
CAAAGAAACC GGTGTCAACG TCAGCGGCAA ACTGTATTCC GACGCACTCG


 


851
GCAACGCACC CGCAGACACC TACATCGGCA TGTACCGCCA CAACATCAAA


 


901
GCCTTAACCA ACGCGATGAA GCAATAA






This corresponds to the amino acid sequence <SEQ ID 1156; ORF 280.a>:










a280.pep




1
MKHPKLTLIA ALLTTAATAA PLPVVTSFSI LGDVAKQIGG ERVSIQSLVG


 


51
ANQDTHAYHM TSGDIKKIRS AKLVLINGLG LEAADIQRAV KQSKVSYAEA


 


101
TKGIQPLKAE EEGGHHHDHD HDHDHDHEGH HHDHGEYDPH VWNDPVLMSA


 


151
YAQNVAEALI KADPEGKVYY QQRLGNYQMQ LKKLHSDAQA AFNAVPAAKR


 


201
KVLTGHDAFS YMGKRYHIEF IAPQGVSSEA EPSAKQVAAI IRQIKREGIK


 


251
AVFTENIKDT RMVDRIAKET GVNVSGKLYS DALGNAPADT YIGMYRHNIK


 


301
ALTNAMKQ*






m280/a280 96.4% identity in 308 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1157>:










g281.seq




1
atgcactacg ccctcgcatc cgtcttctgc ctgtccctca gcgccgcacc


 


51
cgtcggcgta ttcctcgtca tgcgccgtat gagcctgata ggcgacgcat


 


101
tgagccacgc cgtcctgccc ggtgccgccg tcggctacat gtttgccggc


 


151
ttgagcctgc ccgctatggg tgtgggcggg tttgccgccg gtatgctgat


 


201
ggcgctgctt gccggactcg tcagccgctt taccaccctg aaagaagatg


 


251
ccaactttgc cgccttttac ctgagcagcc tcgccatcgg cgtaatcctc


 


301
atcagcaaaa acggcagcag cgtcgattta ctccacctcc ttttcggatc


 


351
tgtgcttgcc gtcgatattc ccgcactgca actcatcgcc gccgtctccg


 


401
gcctcacgct cattaccctt gccgtcatct accgccccct ggtgctagaa


 


451
agcatagacc cccttttcct caagtccgtc aacggcaaag gcgggctttg


 


501
gcacgtcatt ttcctcatcc tcgtcgttat gaacctcgta tccggcttcc


 


551
aagctctcgg catcctgatg tcggtcggaa ttatgatgct gcccgccatt


 


601
accgcccgtt tatgggcaag aaatatgggg acgctcattc tgttgtccgt


 


651
cctcatcgcc cttttttgcg gtttgatcgg gctgctcatt tcctaccaca


 


701
tcgaaatccc ttccggcccc gccatcatcc tctgttgcag cgtcctttat


 


751
cttttttccg tcatactcgg caaagaaggc ggcatcttgc ccaaatggtt


 


801
caaaaaccac cgccaccaca ccacctga






This corresponds to the amino acid sequence <SEQ ID 1158; ORF 281.ng>:










g281.pep




1
MHYALASVFC LSLSAAPVGV FLVMRRMSLI GDALSHAVLP GAAVGYMFAG


 


51
LSLPAMGVGG FAAGMLMALL AGLVSRFTTL KEDANFAAFY LSSLAIGVIL


 


101
ISKNGSSVDL LHLLFGSVLA VDIPALQLIA AVSGLTLITL AVIYRPLVLE


 


151
SIDPLFLKSV NGKGGLWHVI FLILVVMNLV SGFQALGILM SVGIMMLPAI


 


201
TARLWARNMG TLILLSVLIA LFCGLIGLLI SYHIEIPSGP AIILCCSVLY


 


251
LFSVILGKEG GILPKWFKNH RHHTT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1159>:









m281.seq (partial)










1
ATGCGCTACG CCCTCGCATC CGTCTTCTGC CTGTCCCTCA GTGCCGCACC



 


51
CGTCGGCGTA TTCCTCGTCA TGCGCCGTAT GAGCCTGATA GGCGACGCAT


 


101
TGAGCCACGC CGTCCTGCCC GGTGCCGCCG TCGGCTACAT GTTTGCCGGC


 


151
TTGAGCCTGC CCGCCATGGG TTTGGGCGGC GTAGCCGCAG GCATGCTGAT


 


201
GGCACTGCTT GCCGGACTCG TCAGCCGCTT CACCACCCTG AAAGAAGATG


 


251
CCAACTTTGC CGCCTTTTAT CTCAGCAGCC TCGCCATCGG CGTAGTCCTC


 


301
GTCAGCAAAA ACGGGAGCAG CGTCGATTTG CTCCACCTCC TTTTCGGCTC


 


351
TGTACTTGCC GTCGATATTC CTGCCCTGCA GCTCATCGCC GCCGTCTCCA


 


401
GCCTCACGCT CATTACCCTT GCCGTCATCT ACCGCCCGCT CGTACTCGAA


 


451
AGCATCGACC CCCTGTTTCT CAAATCCGTC GGCGGCAAAG GCGGGCTTTG


 


501
GCACGTCCTC TTTCTCGTCC TGGTCGTCAT GAACCTCGTA TCCGGCTTTC


 


551
AAGCCCTCGG CACACTCATG TCCGTCGGAC TCATGATGCT GCCAGCCATT


 


601
ACCGCCCGCC TGTGGGCGAA GCATATGGGC GCACTCATCC TCCTATCCGT


 


651
TCTGACAGCC CTGCTGTGCG GCTTGAGCGG ACTGCTCATT TCCTACCACA


 


701
TCGAAATTCC TTCCGGTCCC GCCATCATCC TCTGTTGCAG CGTCCTTTAT


 


751
CTCTTTTCCG TCATACTCGG CAAAGAAGGC GGCATTCTGA CC..






This corresponds to the amino acid sequence <SEQ ID 1160; ORF 281>:









m281.pep (partial)










1
MRYALASVFC LSLSAAPVGV FLVMRRMSLI GDALSHAVLP GAAVGYMFAG



 


51
LSLPAMGLGG VAAGMLMALL AGLVSRFTTL KEDANFAAFY LSSLAIGVVL


 


101
VSKNGSSVDL LHLLFGSVLA VDIPALQLIA AVSSLTLITL AVIYRPLVLE


 


151
SIDPLFLKSV GGKGGLWHVL FLVLVVMNLV SGFQALGTLM SVGLMMLPAI


 


201
TARLWAKHMG ALILLSVLTA LLCGLSGLLI SYHIEIPSGP AIILCCSVLY


 


251
LFSVILGKEG GILT..






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 281 shows 93.5% identity over a 263 aa overlap with a predicted ORF (ORF 281.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1161>:










a281.seq




1
ATGCGCTACG CCCTCGCATC CGTCTTCTGC CTGTCCCTCA GTGCCGCACC


 


51
CGTCGGCGTA TTCCTCGTCA TGCGCCGTAT GAGCCTGATA GGCGACGCAT


 


101
TGAGCCACGC CGTCCTGCCC GGTGCCGCCG TCGGCTACAT GTTTGCCGGC


 


151
TTAAGCCTGC CCGCCATGGG TTTGGGCGGC GTAGCCGCAG GTATGCTGAT


 


201
GGCACTGCTT GCCGGACTCG TCAGCCGCTT CACCACCCTG AAAGAAGATG


 


251
CCAACTTTGC CGCCTTTTAT CTCAGCAGCC TCGCCATCGG TGTAGTCCTC


 


301
GTCAGCAAAA ACGGCAGCAG CGTCGATTTG CTCCACCTCC TTTTCGGCTC


 


351
CGTACTTGCC GTCGATATTC CTGCCCTGCA ACTCATCGCC GCCGTATCCA


 


401
CCCTCACACT GCTTACCCTT GCCGTCATCT ACCGCCCGCT CGTACTCGAA


 


451
AGCATCGACC CCCTGTTTCT CAAATCTGTC GGCGGCAAAG GCGGGCTTTG


 


501
GCACGTCCTC TTTCTCGTCC TGGTCGTCAT GAACCTCGTA TCCGGCTTTC


 


551
AAGCCCTCGG CACACTCATG TCCGTCGGAC TTATGATGCT GCCAGCCATT


 


601
ACCGCCCGCC TATGGGCGAA GCACATGGGC GCACTCATCC TCCTATCCGT


 


651
TCTGACAGCC CTGCTGTGCG GCTTGAGCGG ACTGCTCATT TCCTACCACA


 


701
TCGAAATTCC TTCCGGTCCC GCCATCATCC TCTGTTGCAG CGTCCTTTAT


 


751
CTCTTTTCCG TCATACTCGG CAAAGAAGGC GGCATTCTGA CCAAATGGCT


 


801
CAAAAACCAC CGCCACCACA CCACCTGA






This corresponds to the amino acid sequence <SEQ ID 1162; ORF 281.a>:










a281.pep




1
MRYALASVFC LSLSAAPVGV FLVMRRMSLI GDALSHAVLP GAAVGYMFAG


 


51
LSLPAMGLGG VAAGMLMALL AGLVSRFTTL KEDANFAAFY LSSLAIGVVL


 


101
VSKNGSSVDL LHLLFGSVLA VDIPALQLIA AVSTLTLLTL AVIYRPLVLE


 


151
SIDPLFLKSV GGKGGLWHVL FLVLVVMNLV SGFQALGTLM SVGLMMLPAI


 


201
TARLWAKHMG ALILLSVLTA LLCGLSGLLI SYHIEIPSGP AIILCCSVLY


 


251
LFSVILGKEG GILTKWLKNH RHHTT*






m281/a281 99.2% identity in 264 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1163>:










g282.seq




1
atgggattgg gtatggaaat cggcaagctg attgtggctc ttttggtgct


 


51
gatcaatccg tttagcgcgt tgtcgcttta ccttgacctg accaacggac


 


101
acagcacgaa ggagcgcagg aaggtcgcgc ggacggccgc cgtcgccgtg


 


151
tttgccgtga ttgcggtatt tgcgctgatc ggcggtgcgc tattgaaggt


 


201
tttgggcatc agcgtcggtt cgtttcaggt cggcggcggg attttggtgc


 


251
tgctgatcgc catttcgatg atgaacggca acgacaatcc cgccaagcag


 


301
aatctcggcg cgcagccgga aacggggcaa gcgcgccccg cccgcaatgc


 


351
aggggcgatt gccgtcgtgc ccatcgccat accgatcacc atcggtccgg


 


401
gcggtatttc gactgtgatt atttatgctt cggcagccaa aacgtacagc


 


451
gatatcgcgc tgattatcgc ggccggtttg gtggtcagtg cgatttgtta


 


501
tgccatttta atcgttgccg ggaaggtcag ccgcctgctg ggcgcgacgg


 


551
ggctgacgat tttaaaccgc attatgggta tgatgctggc ggcggtatcg


 


601
gtggagatta ttgtgtcggg actgaaaacg atattcccgc aactggcagg


 


651
ttga






This corresponds to the amino acid sequence <SEQ ID 1164; ORF 282.ng>:










g282.pep




1
MGLGMEIGKL IVALLVLINP FSALSLYLDL TNGHSTKERR KVARTAAVAV


 


51
FAVIAVFALI GGALLKVLGI SVGSFQVGGG ILVLLIAISM MNGNDNPAKQ


 


101
NLGAQPETGQ ARPARNAGAI AVVPIAIPIT IGPGGISTVI IYASAAKTYS


 


151
DIALIIAAGL VVSAICYAIL IVAGKVSRLL GATGLTILNR IMGMMLAAVS


 


201
VEIIVSGLKT IFPQLAG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1165>:










m282.seq




1
ATGGGATTGG GCATGGAAAT CGGCAAGCTG ATTGTGGCTT TTTTGGTGCT


 


51
GATTAATCCG TTTAGCGCGT TGTCGCTTTA CCTTGACCTG ACCAACGGGC


 


101
ACAGCACGAA GGAGCGCAGG AAGGTCGCGC GGACGGCCGC CGTTGCCGTG


 


151
TTTGCCGTGA TTGCGGTATT TGCGCTGATC GGCGGTACGC TGCTGAAGGT


 


201
TTTGGGCATC AGCGTCGGTT CGTTTCAGGT CGGCGGCGGG ATTTTGGTGC


 


251
TGCTGATCGC CATTTCGATG ATGAACGGCA ACGACAATCC CGCCAAGCAG


 


301
AATCTCGGCG CGCAGCCGGA AACGGGGCAG GCGCGCCCCG CCCGCAATGC


 


351
CGGAGCGATT GCCGTCGTGC CCATCGCCAT ACCGATCACC ATCGGCCCGG


 


401
GCGGTATTTC GACCGTGATT ATTTACGCTT CGGCGGCTAA AACATACGGC


 


451
GACATCGCGT TGATTATCGC GGCCGGTTTG GTGGTCAGTG CGATTTGTTA


 


501
TGCCATTTTA ATCGTTGCCG GGAAGGTCAG CCGCCTGCTG GGCGCGACGG


 


551
GGCTGACGAT TTTAAACCGC ATTATGGGTA TGATGCTGGC GGCGGTATCG


 


601
GTGGAGATTA TTGTGTCGGG ACTGAAAACG ATATTCCCGC AACTGGCAGG


 


651
TTGA






This corresponds to the amino acid sequence <SEQ ID 1166; ORF 282.ng>:










m282.pep




1
MGLGMEIGKL IVAFLVLINP FSALSLYLDL TNGHSTKERR KVARTAAVAV


 


51
FAVIAVFALI GGTLLKVLGI SVGSFQVGGG ILVLLIAISM MNGNDNPAKQ


 


101
NLGAQPETGQ ARPARNAGAI AVVPIAIPIT IGPGGISTVI IYASAAKTYG


 


151
DIALIIAAGL VVSAICYAIL IVAGKVSRLL GATGLTILNR IMGMMLAAVS


 


201
VEIIVSGLKT IFPQLAG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 282 shows 98.6% identity over a 217 aa overlap with a predicted ORF (ORF 282.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1167>:










a282.seq




1
ATGGGATTGG GCATGGAAAT CGGCAAGCTG ATTGTGGCTT TTTTGGTGCT


 


51
GATTAATCCG TTTAGCGCGT TGTCGCTTTA CCTTGACCTG ACCAACGGGC


 


101
ACAGCACGAA GGAGCGCAGG AAGGTCGCGC GGACGGCCGC CGTTGCCGTG


 


151
TTTGCCGTGA TTGCGGTATT TGCGCTGATC GGCGGTACGC TGCTGAAGGT


 


201
TTTGGGCATC AGCGTCGGTT CGTTTCAGGT CGGCGGCGGA ATTTTGGTGT


 


251
TGCTGATTGC CATTTCGATG ATGAACGGCA ACGACAATCC CGCCAAGCAG


 


301
AATCTCGGCG CGCAGCCGGA AACGGGGCAG GTGCGCCCCG CCCGCAATGC


 


351
CGGAGCGATT GCCGTCGTGC CCATCGCCAT ACCGATCACC ATCGGCCCGG


 


401
GCGGTATTTC GACCGTGATT ATTTACGCTT CGGCGGCTAA AACATACGGC


 


451
GACATCGCGT TGATTATCGC GGCCGGTTTG GTGGTCAGTG CGATTTGTTA


 


501
TGCCATTTTA ATCGTTGCCG GGAAGGTCAG CCGCCTGCTG GGTGCGACGG


 


551
GGCTGACGAT TTTAAACCGT ATCATGGGTA TGATGCTGGC GGCGGTATCG


 


601
GTGGAGATTA TTGTGTCGGG ACTGAAAATG ATATTCCCGC AACTGGCAGG


 


651
TTGA






This corresponds to the amino acid sequence <SEQ ID 1168; ORF 282.a>:










a282.pep




1
MGLGMEIGKL IVAFLVLINP FSALSLYLDL TNGHSTKERR KVARTAAVAV


 


51
FAVIAVFALI GGTLLKVLGI SVGSFQVGGG ILVLLIAISM MNGNDNPAKQ


 


101
NLGAQPETGQ VRPARNAGAI AVVPIAIPIT IGPGGISTVI IYASAAKTYG


 


151
DIALIIAAGL VVSAICYAIL IVAGKVSRLL GATGLTILNR IMGMMLAAVS


 


201
VEIIVSGLKM IFPQLAG*






m282/a282 99.1% identity in 217 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1169>:










g283.seq




1
atgaactttg ctttatccgt catcacattt accctcgcct ctttcctgcc


 


51
cgtcccgcct gccggaaccg ccgtctttac ttggaaagac ggcggcggca


 


101
acagctattc ggatgtgccg aaacagcttc atcccgacca gagccaaatc


 


151
ctcaacctgc ggacgctcca aaccaaaccg gcggtcaagc ccaaacctgc


 


201
cgtcgatacg aatgcggaca gtgcgaagga aaacgaaaag gatatcgccg


 


251
agaaaaacgg gcagcttgag gaagaaaaga aaaaaattgc cgaaaccgaa


 


301
cggcagaaca aagaagaaaa ctgccggatt tcaaaaatga acctgaaggc


 


351
ggtgggaaac tcaaatgcga aaaacaagga tgatttgatc cgtaaataca


 


401
ataacgccgt aaacaaatac tgccgttaa






This corresponds to the amino acid sequence <SEQ ID 1170; ORF 283.ng>:










g283.pep




1
MNFALSVITF TLASFLPVPP AGTAVFTWKD GGGNSYSDVP KQLHPDQSQI


 


51
LNLRTLQTKP AVKPKPAVDT NADSAKENEK DIAEKNGQLE EEKKKIAETE


 


101
RQNKEENCRI SKMNLKAVGN SNAKNKDDLI RKYNNAVNKY CR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1171>:










m283.seq




1
ATGAACTTTG CTTTATCCGT CATTATGTTG ACCCTCGCCT CTTTCCTGCC


 


51
CGTCCCGCCT GCCGGAGCCG CCGTCTTTAC TTGGAAGGAC GGCGGCGGCA


 


101
ACAGCTATTC GGATGTACCG AAACAGCTTC ATCCCGACCA AAGCCAAATC


 


151
TTAAACCTGC GGACGCGCCA AACCAAACCG GCGGTCAAAC CCGCCCAAGC


 


201
CGACGCAGGG AAGCGCACAG ACGGCGCGGC ACAGGAAAAC AATCCCGACA


 


251
CTGCCGAGAA AAACCGGCAG CTTGAGGAAG AAAAGAAAAG AATTGCCGAA


 


301
ACCGAACGGC AGAACAAAGA AGAAAACTGC CGGATTTCAA AAATGAACCT


 


351
GAAGGCGGTG GGAAATTCAA ATGCAAAAAA CAAGGATGAT TTGATTCGGA


 


401
AATACAATAA CGCCGTAAAC AAATACTGCC GTTAA






This corresponds to the amino acid sequence <SEQ ID 1172; ORF 283>:










m283.pep




1
MNFALSVIML TLASFLPVPP AGAAVFTWKD GGGNSYSDVP KQLHPDQSQI


 


51
LNLRTRQTKP AVKPAQADAG KRTDGAAQEN NPDTAEKNRQ LEEEKKRIAE


 


101
TERQNKEENC RISKMNLKAV GNSNAKNKDD LIRKYNNAVN KYCR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m283/g283 86.1% identity in 144 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1173>:










a283.seq




1
ATGAACTTTG CTTTATCCGT CATTATGTTG ACCCTCGCCT CTTTCCTGCC


 


51
CGTCCCGCCT GCCGGAGCCG CCGTCTTTAC TTGGAAGGAC GGCGGCGGCA


 


101
ACAGCTATTC GGATGTACCG AAACAGCTTC ATCCCGACCA AAGCCAAATC


 


151
TTAAACCTGC GGACGCGCCA AACCAAACCG GCGGTCAAAC CCGCCCAAGC


 


201
CGACGCAGGG AAGCGCACAG ACGGCGCGGC ACAGGAAAAC AATCCCGACA


 


251
CTGCCGAGAA AAACCGGCAG CTTGAGGAAG AAAAGAAAAG AATTGCCGAA


 


301
ACCGAACGGC AGAACAAAGA AGAAAACTGC CGGATTTCAA AAATGAACCT


 


351
GAAAGCGGTG GGAAATTCAA ATGCAAAAAA CAAGGATGAT TTGATTCGGA


 


401
AATACAATAA CGCCGTAAAC AAATACTGCC GTTAA






This corresponds to the amino acid sequence <SEQ ID 1174; ORF 283.a>:










a283.pep




1
MNFALSVIML TLASFLPVPP AGAAVFTWKD GGGNSYSDVP KQLHPDQSQI


 


51
LNLRTRQTKP AVKPAQADAG KRTDGAAQEN NPDTAEKNRQ LEEEKKRIAE


 


101
TERQNKEENC RISKMNLKAV GNSNAKNKDD LIRKYNNAVN KYCR*






m283/a283 100.0% identity in 144 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1175>:










g284.seq.




1
atgccgtctg aaactcgaaa tcggtttcag acggcattgg tttacgcggc


 


51
aggttggggc ttagcggtct ttgtaacggc attcgctttt gcctgcaaaa


 


101
gagtcgccgg ctttgcgttt gcctttgaag ccttcgccgg tttttttgaa


 


151
actgtctttc ttaaagcctt ctttcttgaa accttcgccg cgcgttttgc


 


201
cgccgaagcc ttctttgccc ggtttatgat cgccgcgccg gccgccggat


 


251
ttcctatcgc cccagccgcc tttgcctttc ggcttgccgc ctgcggattt


 


301
gcgtttgcgg gccggctcca tgccttcgat ggtcagttcg ggcagtttgc


 


351
ggttaatgta tttttcgatt ttgtggactt tgacgtattc gttcacttcg


 


401
gcaaacgtaa tcgcaatacc cgtgcggcct gcgcggccgg tgcgcccgat


 


451
gcggtggacg tagtcttccg cctgtttcgg caggtcgtag tttatgacgt


 


501
gggtaatggt cggtacgtca ataccgcgtg cggcaacgtc ggtggcaacc


 


551
aaaattttgc agcggccttt acgcaaatcc gtcagcgtgc ggttgcgcca


 


601
gccctgcggc atatcgccgt gcaggcagtt ggcggcgaaa cctttttcgt


 


651
acaattcatc cgcgatgact tcggtcatcg ctttggtgga cgtgaaaatc


 


701
acacattggt cgatgttggc atcgcgcagg atgtggtcga gcaggcggtt


 


751
tttgtggcgc atatcgtcgc agtacaacaa ctgctcttcg attttgcctt


 


801
ggccgtccac gcgttcgact tcgataattt cagagtcttt ggtcagtttg


 


851
cgcgccagtt tgccgactgc gccgtcccaa gtggcggaga acaataa






This corresponds to the amino acid sequence <SEQ ID 1176; ORF 284.ng>:










g284.pep




1
MPSETRNRFQ TALVYAAGWG LAVFVTAFAF ACKRVAGFAF AFEAFAGFFE


 


51
TVFLKAFFLE TFAARFAAEA FFARFMIAAP AAGFPIAPAA FAFRLAACGF


 


101
AFAGRLHAFD GQFGQFAVNV FFDFVDFDVF VHFGKRNRNT RAACAAGAPD


 


151
AVDVVFRLFR QVVVYDVGNG RYVNTACGNV GGNQNFAAAF TQIRQRAVAP


 


201
ALRHIAVQAV GGETFFVQFI RDDFGHRFGG RENHTLVDVG IAQDVVEQAV


 


251
FVAHIVAVQQ LLFDFALAVH AFDFDNFRVF GQFARQFADC AVPSGGEQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1177>:










m284.seq..




1
ATGCCGTCTG AAACTCGAAA TCGGTTTCAG ACGGCATTGG TTTATGCGGC


 


51
AGGTTGGGGC TTAGCGGTCT TTGTAACGGC GTTCGCCTTT GCCTGCAAAA


 


101
GAATCGCCGG CTTTGCGTTT GCCTTTGAAG CCTTCGCCGG TTTTTTTGAA


 


151
ACCGTCTCTC TTAAAGCCTT CTTTCTTGAA ACCTTCGCCG CGCGTTTTGC


 


201
CGCCGAAGCC TTCTTTGCTC GGTTTATGAT CGCCGCGCCA ACCGCCGGAT


 


251
TTACGATCGC CCCAGCCGCC TTTGCCTTTC GGCTTGCCGC CTGCGGATTT


 


301
GCGTTTGCGG GTCGGTTCCA TGCCTTCGAT GGTCAGTTCG GGCAGTTTTC


 


351
GGTTAATGTA TTTTTCGATT TTGTGGACTT TGACGTATTC GTTCACTTCG


 


401
GCAAACGTAA TCGCAATACC CGTGCGGCCT GCGCGGCCGG TGCGCCCGAT


 


451
GCGGTGGACG TAGTCTTCCG CCTGTTTCGG CAGGTCGTAG TTGATAACGT


 


501
GGGTAATGGT CGGTACGTCG ATACCGCGTG CGGCAACATC GGTGGCAACC


 


551
AAAATTTTGC AGCGGCCTTT ACGCAAATCC ATCAGCGTGC GGTTGCGCCA


 


601
GCCTTGCGGC ATATCGCCGT GCAGGCAGTT TGCGGCGAAA CCTTTTTCGT


 


651
ACAGTTCATC CGCAATGACT TCGGTCATGG CTTTGGTGGA CGTGAAAATC


 


701
ACGCATTGAT CGATATTGGC ATCGCGCAAG ATATGATCGA GCAGGCGGTT


 


751
TTTGTGGCGC ATATCGTCGC AGTACAGCAG TTGTTCTTCG ATTTTGCCTT


 


801
GATCGTCCAC GCGTTCGACT TCGATGATTT CAGGGTCTTT GGTCAGTTTG


 


851
CGCGCCAGTT TGCCGACCGC GCCGTCCCAA GTGGCGGAGA ACAACAAAGT


 


901
CTGACGGTCG CTCGGCGTTG CTTCCACGAT GGTTTCGATG TCGTCGATAA


 


951
AGCCCATATC CAACATACGG TCGGCTTCGT CCAAAATCAG CACTTCCAAA


 


1001
CGTTCAAAAT CAACTTTGCC GCTTTGCATC AGGTCCATCA GACGGCCCGG


 


1051
CGTGGCGACA ATCAGATCGA CCGGTTTGCT CAGGGCACGG GTTTGGTAGC


 


1101
CGAAAGACGC GCCGCCGACG ATGCTGACGG TGCGGAACCA ACGCATATTT


 


1151
TTGGCATACG CCAGCGCGTT TTTCTCGACT TGAGCCGCCA GTTCGCGGGT


 


1201
CGGGGTCAAC ACCAAAGCAC GCGGGCCTTT GCCCGGTTTT TCGCTGCGTT


 


1251
TGGTCAGTTT TTGCAAAGTC GGTAA






This corresponds to the amino acid sequence <SEQ ID 1178; ORF 284>:










m284.pep




1
MPSETRNRFQ TALVYAAGWG LAVFVTAFAF ACKRIAGFAF AFEAFAGFFE


 


51
TVSLKAFFLE TFAARFAAEA FFARFMIAAP TAGFTIAPAA FAFRLAACGF


 


101
AFAGRFHAFD GQFGQFSVNV FFDFVDFDVF VHFGKRNRNT RAACAAGAPD


 


151
AVDVVFRLFR QVVVDNVGNG RYVDTACGNI GGNQNFAAAF TQIHQRAVAP


 


201
ALRHIAVQAV CGETFFVQFI RNDFGHGFGG RENHALIDIG IAQDMIEQAV


 


251
FVAHIVAVQQ LFFDFALIVH AFDFDDFRVF GQFARQFADR AVPSGGEQQS


 


301
LTVARRCFHD GFDVVDKAHI QHTVGFVQNQ HFQTFKINFA ALHQVHQTAR


 


351
RGDNQIDRFA QGTGLVAERR AADDADGAEP THIFGIRQRV FLDLSRQFAG


 


401
RGQHQSTRAF ARFFAAFGQF LQSR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m284/g284 92.3% identity in 298 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1179>:










a284.seq




1
ATGCCGTCTG AAACTCGAAA TCGGTTTCAG ACGGCATTGG TTTATGCGGC


 


51
AGGTTGGGGC TTAGCGGTCT TTGTAACGGC GTTCGCCTTT GCCTGCAAAA


 


101
GAATCGCCGG CTTTGCGTTT GCCTTTGAAG CCTTCGCCGG TTTTTTTGAA


 


151
ACCGTCTCTC TTAAAGCCTT CTTTCTTGAA ACCTTCGCCG CGCGTTTTGC


 


201
CGCCGAAGCC TTCTTTGCTC GGTTTATGAT CGCCGCGCCA ACCGCCGGAT


 


251
TTACGATCGC CCCAGCCGCC TTTGCCTTTC GGCTTGCCGC CTGCGGATTT


 


301
GCGTTTGCGG GTCGGTTCCA TGCCTTCGAT GGTCAGTTCG GGCAGTTTTC


 


351
GGTTAATGTA TTTTTCGATT TTGTGGACTT TGACGTATTC GTTCACTTCG


 


401
GCAAACGTAA TCGCAATACC CGTGCGGCCT GCGCGGCCGG TGCGCCCGAT


 


451
GCGGTGGACG TAGTCTTCCG CCTGTTTCGG CAGGTCGTAG TTGATAACGT


 


501
GGGTAATGGT CGGTACGTCG ATACCGCGTG CGGCAACGTC GGTGGCAACC


 


551
AAAATTTTGC AGCGGCCTTT GCGCAAATCC ATCAGCGTGC GGTTGCGCCA


 


601
GCCTTGCGGC ATATCGCCGT GCAGGCAGTT GGCGGCGAAA CCTTTTTCGT


 


651
ACAATTCATC CGCGATGACT TCGGTCATGG CTTTGGTGGA CGTGAAAATC


 


701
ACGCATTGAT CGATGTCGGC ATCGCGCAAG ATATGATCGA GCAGGCGGTT


 


751
TTTGTGGCGC ATATCGTCGC AGTACAGCAG TTGTTCTTCG ATTTTGCCTT


 


801
GGTCGTCCAC GCGTTCGACT TCGATGATTT CAGGGTCTTT GGTCAGTTTG


 


851
CGCGCCAGTT TGCCGACCGC GCCGTCCCAA GTGGCGGAGA ACAACAAAGT


 


901
CTGACGGTCT TCCGGCGTGG CTTCGACGAT GGTTTCGATG TCGTCGATAA


 


951
AGCCCATATC CAACATACGG TCGGCTTCGT CCAAAATCAG CACTTCCAAG


 


1001
CGGGCGAAAT CGACTTTGCC GCTTTGCATC AAGTCCATCA GACGGCCCGG


 


1051
CGTGGCGACA ATCAGATCGA CCGGTTTGCT CAGGGCGCGG GTTTGGTAGC


 


1101
CGAACGATGC ACCACCGACG ATGCTGACGG TACGGAACCA ACGCATATTT


 


1151
TTGGCATACG CCAGCGCGTT TTTCTCGACT TGAGCCGCCA ATTCGCGGGT


 


1201
CGGCGTCAAC ACCAACGCGC GCGGGCCTTT GCCCGGTTTT TCGCTGCGTT


 


1251
TGGTCAGTCG CTGCAAAGTC GGTAA






This corresponds to the amino acid sequence <SEQ ID 1180; ORF 284.a>:










a284.pep




1
MPSETRNRFQ TALVYAAGWG LAVFVTAFAF ACKRIAGFAF AFEAFAGFFE


 


51
TVSLKAFFLE TFAARFAAEA FFARFMIAAP TAGFTIAPAA FAFRLAACGF


 


101
AFAGRFHAFD GQFGQFSVNV FFDFVDFDVF VHFGKRNRNT RAACAAGAPD


 


151
AVDVVFRLFR QVVVDNVGNG RYVDTACGNV GGNQNFAAAF AQIHQRAVAP


 


201
ALRHIAVQAV GGETFFVQFI RDDFGHGFGG RENHALIDVG IAQDMIEQAV


 


251
FVAHIVAVQQ LFFDFALVVH AFDFDDFRVF GQFARQFADR AVPSGGEQQS


 


301
LTVFRRGFDD GFDVVDKAHI QHTVGFVQNQ HFQAGEIDFA ALHQVHQTAR


 


351
RGDNQIDRFA QGAGLVAERC TTDDADGTEP THIFGIRQRV FLDLSRQFAG


 


401
RRQHQRARAF ARFFAAFGQS LQSR*






m284/a284 94.8% identity in 424 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1181>:










g285.seq




1
atgaccgata ccacaccgac agataccgat ccgaccgaaa acggcacgcg


 


51
caaaatgccg tctgaacacc gccccgcccc gccggcaaaa aaacgccgcc


 


101
cgctgctgaa gctgtcggcg gcactgctgt ctgtcctgat tttggcagta


 


151
tgtttcctcg gctggatcgc cggtacggaa gcaggtttgc gcttcgggct


 


201
gtaccaaatc ccgtcctggt tcggcgtaaa catttcctcc caaaacctca


 


251
aaggcacact gctcgacggc ttcgacggcg acaactggtc gatagaaacc


 


301
gagggggcag accttaaaat cagccgcttc cgcttcgcgt ggaaaccgtc


 


351
cgaactgatg cgccgcagcc tgcacatcac cgacatctcc gccggcgaca


 


401
tcgccatcgt aaccaaaccg actccgccta aagaagaacg cccgcctcaa


 


451
ggcctgcccg acagcataga cctgcccgcc gctgtctatc tcgaccgctt


 


501
cgagacgggc aaaatcagca tgggcaaaac ctttgacaaa caaaccgtct


 


551
atctcgaacg cctcaacgcg gcataccgtt acgaccgtaa agggcaccgc


 


601
ctcgacctga aggccgccga cacgccgtgg agcagttcgt cggggtcagc


 


651
ctcggtcggc ttgaaaaaac cgtttgccct cgataccgcc atttacacca


 


701
aaggcggatt cgaaggcgaa accatacaca gtacggcgcg gctgagcggc


 


751
agcctgaagg atgtgcgcgc cgaactgacg atcgacggcg gcaatatccg


 


801
cctctcggga aaatccgtca tccacccgtt tgccgaatca ttggataaaa


 


851
cattggaaga agtactggtc aaaggattca acatcaatcc gtccgccttc


 


901
gtgccttccc tgcccgatgc cgggctgaat ttcgacctga ccgccatccc


 


951
gtcgttttca gacggcatcg cgctggaagg ctcgctcgat ttggaaaaca


 


1001
ccaaagccgg ctttgccgac cgcaacggca tccccgtccg tcaggttttg


 


1051
ggcggctttg tcatccggca ggacggcacg gtgcatatcg gcaatacgtc


 


1101
cgccgccctg ctcggacggg gcggcatcag gctgtcgggc aaaatcgaca


 


1151
ccgaaaaaga catccttgat ttaaatatag gcatcaactc cgtcggcgcg


 


1201
gaagacgtgc tgcaaaccgc gttcaaaggc aggttggacg gcagcatcgg


 


1251
catcggcggc acgaccgcct cgcccaaaat ctcttggcaa ctcggcaccg


 


1301
gcacggcacg cacggacggc agcctcccca tcgcaagcga ccccgcaaac


 


1351
gaacagcgga aactggtgtt cgacaccgtc aacatctccg ccggggaagg


 


1401
cagcctgacc gcgcaaggct atctcgagct gtttaaagac cgcctgctca


 


1451
agctggacat ccgttcccgc gcattcgacc cttcgcgcat cgatccgcaa


 


1501
tttccggcag gcaatatcaa cggttcgatt catcttgccg gtgaactggc


 


1551
aaaagagaaa tttacgggca aaatgcgttt tttgcccggt acgttcaacg


 


1601
gcgtgccgat tgccggcagc gccgacattg tttacgagtc ccgccacctt


 


1651
ccgcgcgccg ccgtcgattt gcggttgggg cggaacatcg tcaaaacaga


 


1701
cggcggcttc ggcaaaaaag gcgaccggct taacctcaat atcaccgcac


 


1751
ccgatttatc ccgtttcggt ttcggactcg cggggtcttt aaatgtacgc


 


1801
ggacaccttt ccggcgattt ggacggcggc atccgaacct ttgaaaccga


 


1851
cctttccggc acggcgcgca acttacacat cggcaaagcg gcagacatcc


 


1901
gttcgctcga ttttaccctc aaaggctcac ccggcacaag ccgcccgatg


 


1951
cgcgccgata tcaagggcgg ccgcctttcc ctgtcgggcg gcgcggcggt


 


2001
tgtcgatacc gccggcctga cgctggaagg tacgggcgcg cagcaccgca


 


2051
tccgcacaca cgccgccatg acgctggacg gcaaaccgtt caaactcgat


 


2101
ttggacgctt caggcggcat caacagggaa cttacccgat ggaaaggcag


 


2151
catcggcatc ctcgacatcg gcggcgcatt caacctcaag ctgcaaaacc


 


2201
gtatgacgct cgaagccggt gcggaacacg tggcggcaag tgcggcaaat


 


2251
tggcaggcaa tgggcggcag cctcaacctg caacactttt cttgggacag


 


2301
gaaaaccggc atatcggcaa aaggcggcgc acgcggcctg cacatcgccg


 


2351
agttgcacaa tttcttcaaa ccgcccttcg aacacaatct ggttttaaac


 


2401
ggcgactggg atgtcgccta cgggcacaac gcgcgcggct acctcaatat


 


2451
cagccggcaa agcggcgatg ccgtattgcc cggcgggcag gctttgggtt


 


2501
tgaacgcatt ttccctgaaa acgcgctttc aaaacgaccg catcggaatc


 


2551
ctgcttgacg gcggcgcgcg tttcggacgg attaacgccg atttgggcat


 


2601
cggcaacgcc ttcggcggca atatggcaaa tacaccgctc ggcggcagga


 


2651
ttacagcctc ccttcccgac ttgggcgcat tgaagccctt tctgcccgcc


 


2701
gccgcgcaaa acattaccgg cagcctgaat gcctccgcgc aaatcggcgg


 


2751
acgggtaggc tctccgtccg tcaatgccgc cgtcaacggt agcagcaact


 


2801
acgggaaaat caacggcaat atcaccgtcg ggcaaagccg ctccttcgat


 


2851
accgcacctt tgggcggcag gctcaacctg accgttgccg atgccgaagc


 


2901
attccgcaac ttcctaccgg tcggacaaac cgtcaaaggc agcctgaatg


 


2951
ccgccgtaac cctcggcggc agcatcgccg acccgcactt gggcggcagt


 


3001
atcaacggcg acaagctcta ttaccgcaac caaacccaag gcatcatctt


 


3051
ggacaacggc tcgctgcgtt cgcatattgc aggcaggaaa tgggtaatcg


 


3101
acagcctgaa attccggcac gaagggacgg cggaactctc cggcacggtc


 


3151
agcatggaaa acagcgtgcc cgatgtcgat atcggcgcgg tgttcgacaa


 


3201
ataccgcatc ctgtcccgcc ccaaccgccg cctgacggtt tccggcaaca


 


3251
cccgcctgcg ctattcgccg caaaaaggca tatccgttac cggtatgatt


 


3301
aaaactgatc aggggctgtt cggttcgcaa aaatcctcga tgccgtccgt


 


3351
cggcgacgat gtcgtcgtat tgggcgaagt caagaaagag gcggcggcat


 


3401
cgctccccgt caatatgaac ctgactttag acctcaatga cggcatccgc


 


3451
ttctccggct acggcgcgga cgttaccata ggcggcaaac tgaccctgac


 


3501
cgcgcaaccg ggcggaaatg tgcgtggggt gggcacggtc cgcgtcatca


 


3551
aagggcgtta caaagcatac gggcaggatt tagacattac caaaggcaca


 


3601
gtctcctttg tcggcccgct caacgacccc aacctgaaca tccgcgccga


 


3651
acgccgcctt tcccccgtcg gtgcgggcgt ggaaatattg ggcagcctca


 


3701
acagcccgcg cattacgctg acggcaaacg aaccgatgag tgaaaaagac


 


3751
aagctctcct ggctcatcct caaccgtgcc ggcagcggca gcagcggcga


 


3801
caatgccgcc ctgtccgcag ccgcaggcgc gctgcttgcc gggcaaatca


 


3851
acgaccgcat cgggctggtg gatgatttgg gctttaccag caagcgcagc


 


3901
cgcaacgcgc aaaccggcga actcaacccc gccgaacagg tgctgaccgt


 


3951
cggcaaacaa ctgaccggca aactctacat cggctacgaa tacggcatct


 


4001
ccagcgcgga acagtccgtc aaactgattt accggctgac ccgcgccata


 


4051
caggcggttg cccgtatcgg cagccgttcg tcgggcggcg agctgacata


 


4101
caccatacgt ttcgaccgcc tcttcggttc ggacaaaaaa gactccgcag


 


4151
gaaacggcaa agggaaataa






This corresponds to the amino acid sequence <SEQ ID 1182; ORF 284.ng>:










g285.pep




1
MTDTTPTDTD PTENGTRKMP SEHRPAPPAK KRRPLLKLSA ALLSVLILAV


 


51
CFLGWIAGTE AGLRFGLYQI PSWFGVNISS QNLKGTLLDG FDGDNWSIET


 


101
EGADLKISRF RFAWKPSELM RRSLHITDIS AGDIAIVTKP TPPKEERPPQ


 


151
GLPDSIDLPA AVYLDRFETG KISMGKTFDK QTVYLERLNA AYRYDRKGHR


 


201
LDLKAADTPW SSSSGSASVG LKKPFALDTA IYTKGGFEGE TIHSTARLSG


 


251
SLKDVRAELT IDGGNIRLSG KSVIHPFAES LDKTLEEVLV KGFNINPSAF


 


301
VPSLPDAGLN FDLTAIPSFS DGIALEGSLD LENTKAGFAD RNGIPVRQVL


 


351
GGFVIRQDGT VHIGNTSAAL LGRGGIRLSG KIDTEKDILD LNIGINSVGA


 


401
EDVLQTAFKG RLDGSIGIGG TTASPKISWQ LGTGTARTDG SLPIASDPAN


 


451
EQRKLVFDTV NISAGEGSLT AQGYLELFKD RLLKLDIRSR AFDPSRIDPQ


 


501
FPAGNINGSI HLAGELAKEK FTGKMRFLPG TFNGVPIAGS ADIVYESRHL


 


551
PRAAVDLRLG RNIVKTDGGF GKKGDRLNLN ITAPDLSRFG FGLAGSLNVR


 


601
GHLSGDLDGG IRTFETDLSG TARNLHIGKA ADIRSLDFTL KGSPGTSRPM


 


651
RADIKGGRLS LSGGAAVVDT AGLTLEGTGA QHRIRTHAAM TLDGKPFKLD


 


701
LDASGGINRE LTRWKGSIGI LDIGGAFNLK LQNRMTLEAG AEHVAASAAN


 


751
WQAMGGSLNL QHFSWDRKTG ISAKGGARGL HIAELHNFFK PPFEHNLVLN


 


801
GDWDVAYGHN ARGYLNISRQ SGDAVLPGGQ ALGLNAFSLK TRFQNDRIGI


 


851
LLDGGARFGR INADLGIGNA FGGNMANTPL GGRITASLPD LGALKPFLPA


 


901
AAQNITGSLN ASAQIGGRVG SPSVNAAVNG SSNYGKINGN ITVGQSRSFD


 


951
TAPLGGRLNL TVADAEAFRN FLPVGQTVKG SLNAAVTLGG SIADPHLGGS


 


1001
INGDKLYYRN QTQGIILDNG SLRSHIAGRK WVIDSLKFRH EGTAELSGTV


 


1051
SMENSVPDVD IGAVFDKYRI LSRPNRRLTV SGNTRLRYSP QKGISVTGMI


 


1101
KTDQGLFGSQ KSSMPSVGDD VVVLGEVKKE AAASLPVNMN LTLDLNDGIR


 


1151
FSGYGADVTI GGKLTLTAQP GGNVRGVGTV RVIKGRYKAY GQDLDITKGT


 


1201
VSFVGPLNDP NLNIRAERRL SPVGAGVEIL GSLNSPRITL TANEPMSEKD


 


1251
KLSWLILNRA GSGSSGDNAA LSAAAGALLA GQINDRIGLV DDLGFTSKRS


 


1301
RNAQTGELNP AEQVLTVGKQ LTGKLYIGYE YGISSAEQSV KLIYRLTRAI


 


1351
QAVARIGSRS SGGELTYTIR FDRLFGSDKK DSAGNGKGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1183>:










m285.seq




1
ATGACCGATA CCGCACCGAC AGATACCGAT CCGACCGAAA ACGGCACGCG


 


51
CAAAATGCCG TCTGAACACC GCCCTACCCC GCCGGCAAAA AAACGCCGCC


 


101
CGTTGCTGAA GCTGTCGGCG GCACTGCTGT CTGTCCTGAT TTTGGCAGTA


 


151
TGTTTCCTCG GCTGGCTCGC CGGTACGGAA GCAGGTTTGC GCTTCGGGCT


 


201
GTACCAAATC CCGTCTTGGT TCGGCGTAAA CATTTCCTCC CAAAACCTCA


 


251
AAGGCACGCT GCTCGACGGC TTCGACGGCG ACAACTGGTC GATAGAAACC


 


301
GAGGGGGCAG ACCTTAAAAT CAGCCGCTTC CGCTTCGCGT GGAAACCGTC


 


351
CGAACTGATG CGCCGCAGCC TGCACATTAC CGAAATTTCC GCCGGCGACA


 


401
TCGCCATCGT TACCAAACCG ACTCCGCCTA AAGAAGAACG CCCGCCGCTC


 


451
AGCCTTCCCG ACAGCATAGA CCTGCCTGCC GCCGTCTATC TCGACCGCTT


 


501
CGAGACGGGC AAAATCAGCA TGGGCAAAGC CTTTGACAAA CAAACCGTCT


 


551
ATCTCGAACG GCTGGATGCT TCATACCGTT ACGACCGCAA AGGACACCGC


 


601
CTTGACCTGA AGGCCGCCGA CACGCCGTGG AGCAGTTCGT CGGGGGCGGC


 


651
CTCGGTCGGC TTGAAAAAAC CGTTTGCCCT CGATACCGCC ATTTACACCA


 


701
AAGGCGGACT CGAAGGCAAA ACCATACACA GTACGGCTCG GCTGAGCGGC


 


751
AGCCTGAAGG ATGTGCGCGC CGAACTGGCG ATCGACGGCG GCAATATCCG


 


801
CCTCTCGGGA AAATCCGTCA TCCACCCGTT TGCCGAATCA TTGGATAAAA


 


851
CATTGGAAGA AGTACTGGTC AAAGGGTTCA ACATCAATCC GGCCGCCTTC


 


901
GTGCCTTCCC TGCCCGATGC CGGACTGAAT TTCGACCTGA CCGCCATCCC


 


951
GTCGTTTTCA GACGGCATCG CGCTGGAAGG TTCGCTCGAT TTGGAAAACA


 


1001
CCAAAGCCGG CTTTGCCGAC CGCAACGGCA TCCCCGTCCG TCAGGTTTTA


 


1051
GGCGGCTTTG TCATCCGGCA GGACGGCACG GTGCATATCG GCAATACGTC


 


1101
CGCCGCCCTG CTCGGACGGG GCGGCATCAG GCTGTCGGGC AAAATCGACA


 


1151
CCGAAAAAGA CATCCTCGAT TTAAATATAG GCATCAACTC CGTCGGCGCG


 


1201
GAAGACGTAC TGCAAACCGC GTTCAAAGGC AGGTTGGACG GCAGCATCGG


 


1251
CATCGGTGGC ACGACCGCCT CGCCCAAAAT CTCTTGGCAA CTCGGCATCG


 


1301
GCACGGCGCG CACGGACGGC AGCCTCGCCA TTGCAAGCGA CCCAGCAAAC


 


1351
GGACAGCGGA AACTGGTGCT CGACACCGTC AACATCGCCG CCGGGCAAGG


 


1401
CAGCCTGACC GCGCAAGGCT ATCTCGAGCT GTTTAAAGAC CGCCTGCTCA


 


1451
AGCTGGACAT CCGTTCCCGC GCATTCGACC CTTCGCGCAT CGATCCGCAA


 


1501
CTTCCGGCAG GCAATATCAA CGGCTCAATA AACCTTGCCG GCGAACTGGC


 


1551
AAAAGAGAAA TTCACAGGCA AAATGCGGTT TTTACCCGGC ACGTTCAACG


 


1601
GCGTACCGAT TGCCGGCAGT GCCGACATTG TTTACGAGTC CCGCCACCTT


 


1651
CCGCGTGCCG CCGTCGATTT GCGGCTGGGG CGGAACATTA TTAAAACAGA


 


1701
CGGCGGCTTC GGCAAAAAAG GCGACCGGCT TAACCTCAAT ATCACCGCAC


 


1751
CCGATTTATC CCGTTTCGGT TTCGGACTCG CGGGGTCTTT AAATGTACGC


 


1801
GGACACCTTT CCGGTGATTT GGACGGCGGC ATCCGAACCT TTGAAACCGA


 


1851
CCTTTCCGGC GCGGCGCGCA ACCTGCACAT CGGCAAGGCG GCAGACATCC


 


1901
GTTCGCTCGA TTTCACGCTC AAAGGTTCGC CCGACACAAG CCGCCCGATA


 


1951
CGCGCCGACA TCAAAGGCAG CCGCCTTTCG CTGTCGGGCG GAGCGGCGGT


 


2001
TGTCGATACC GCCGACCTGA TGCTGGACGG CACGGGCGTG CAGCACCGCA


 


2051
TCCGCACACA CGCCGCCATG ACGCTGGATG GCAAACCGTT CAAATTCGAT


 


2101
TTGGACGCTT CAGGCGGCAT CAACAGGGAA CTTACCCGAT GGAAAGGCAG


 


2151
CATCGGCATC CTCGACATCG GCGGCGCATT CAACCTCAAG CTGCAAAACC


 


2201
GTATGACGCT CGAAGCCGGT GCGGAACGCG TGGCGGCAAG TGCGGCAAAT


 


2251
TGGCAGGCAA TGGGCGGCAG CCTCAACCTG CAACACTTTT CTTGGGATAA


 


2301
AAAAACCGGC ATATCGGCAA AAGGCGGCGC ACACGGTCTG CATATCGCCG


 


2351
AGTTGCACAA TTTCTTCAAA CCGCCCTTCG AACACAATCT GGTTTTAAAC


 


2401
GGCGACTGGG ATGTCGCCTA CGGGCGCAAC GCGCGCGGCT ACCTCAATAT


 


2451
CAGCCGGCAA AGCGGCGATG CCGTATTGCC CGGCGGGCAG GCTTTGGGTT


 


2501
TGAACGCATT TTCCCTGAAA ACGCGCTTTC AAAACGACCG CATCGGAATC


 


2551
CTGCTTGACG GCGGCGCGCG TTTCGGGCGG ATTAACGCCG ATTTGGGCAT


 


2601
CGCCAACGCC TTCGGCGGCA ATATGGCAAA TGCACCGCTC GGCGGCAGGA


 


2651
TTACCGCCTC CCTTCCCGAC TTGGGCGCAT TGAAGCCCTT TCTGCCCGCC


 


2701
GCCGCGCAAA ACATTACCGG CAGCCTGAAT GCCGCCGCGC AAATCGGCGG


 


2751
ACGGGTAGGC TCTCCGTCCG TCAATGCCGC CGTCAACGGC AGCAGCAACT


 


2801
ACGGGAAAAT CAACGGCAAC ATCACCGTCG GGCAAAGCCG CTCTTTCGAT


 


2851
ACCGCGCCTT TGGGCGGCAG GCTCAACCTG ACCGTTGCCG ATGCCGAAGT


 


2901
ATTCCGCAAC TTCCTACCGG TCGGACAAAC CGTCAAAGGC AGCCTGAATG


 


2951
CCGCCGTAAC CCTCGGCGGC AGCATCGCCG ATCCGCACTT GGGCGGCAGC


 


3001
ATCAACGGCG ACAAACTCTA TTACCGCAAC CAAACCCAAG GCATCATCTT


 


3051
GGACAACGGC TCGCTGCGTT CGCATATCGC GGGCAGGAAA TGGGTAATCG


 


3101
ACAGCCTGAA ATTCCGGCAC GAAGGGACGG CGGAACTCTC CGGTACGGTC


 


3151
GGTATGGAAA ACAGCGGACC CGATGTCGAT ATCGGCGCGG TGTTCGACAA


 


3201
ATACCGCATC CTGTCCCGCC CCAACCGCCG CCTGACGGTT TCCGGCAACA


 


3251
CCCGCCTGCG CTATTCGCCG CAAAAAGGCA TATCCGTTAC CGGGATGATT


 


3301
AAAACGGATC AGGGGCTGTT CGGTTCGCAA AAATCCTCGA TGCCGTCCGT


 


3351
CGGCGACGAT GTCGTCGTAT TAGGCGAAGT CAAAAAAGAG GCGGCGGCAC


 


3401
CGCTCCCCGT CAATATGAAC CTGACTTTAG ACCTCAATGA CGGCATCCGC


 


3451
TTCGCCGGCT ACGGCGCGGA CGTTACCATA GGCGGCAAAC TGACCCTGAC


 


3501
CGCCCAATCG GGCGGAAGCG TACGGGGCGT GGGCACGGTC CGCGTCATCA


 


3551
AAGGGCGTTA TAAGGCATAC GGGCAGGATT TGGACATTAC CAAAGGCACG


 


3601
GTCTCCTTTG TCGGCCCGCT CAACGATCCC AACCTCAACA TCCGCGCCGA


 


3651
ACGCCGCCTT TCCCCCGTCG GTGCGGGCGT GGAAATATTG GGCAGCCTCA


 


3701
ACAGCCCGCG CATTACGCTG ACGGCAAACG AACCGATGAG TGAAAAAGAC


 


3751
AAGCTCTCTT GGCTCATCCT CAACCGCGCC GGCAGCGGCA GCAGCGGCGA


 


3801
CAATGCCGCC CTGTCTGCAG CCGCAGGTGC GCTGCTTGCC GGGCAAATCA


 


3851
ACGACCGCAT CGGGCTGGTG GATGATTTGG GCTTTACCAG CAAGCGCAGC


 


3901
CGCAACGCGC AAACCGGCGA ACTCAACCCC GCCGAACAGG TGCTGACCGT


 


3951
CGGCAAACAA CTGACCGGCA AACTCTACAT CGGCTACGAA TACAGCATCT


 


4001
CCAGCGCGGA ACAGTCCGTC AAACTGATTT ACCGGCTGAC CCGCGCCATA


 


4051
CAGGCGGTTG CCCGTATCGG CAGCCGTTCG TCGGGCGGCG AGCTGACATA


 


4101
CACCATACGT TTCGACCGCT TCTCCGGTTC GGACAAAAAA GACTCCGCCG


 


4151
GAAACGGCAA AGGAAAATAA






This corresponds to the amino acid sequence <SEQ ID 1184; ORF 285>:










m285.pep




1
MTDTAPTDTD PTENGTRKMP SEHRPTPPAK KRRPLLKLSA ALLSVLILAV


 


51
CFLGWLAGTE AGLRFGLYQI PSWFGVNISS QNLKGTLLDG FDGDNWSIET


 


101
EGADLKISRF RFAWKPSELM RRSLHITEIS AGDIAIVTKP TPPKEERPPL


 


151
SLPDSIDLPA AVYLDRFETG KISMGKAFDK QTVYLERLDA SYRYDRKGHR


 


201
LDLKAADTPW SSSSGAASVG LKKPFALDTA IYTKGGLEGK TIHSTARLSG


 


251
SLKDVRAELA IDGGNIRLSG KSVIHPFAES LDKTLEEVLV KGFNINPAAF


 


301
VPSLPDAGLN FDLTAIPSFS DGIALEGSLD LENTKAGFAD RNGIPVRQVL


 


351
GGFVIRQDGT VHIGNTSAAL LGRGGIRLSG KIDTEKDILD LNIGINSVGA


 


401
EDVLQTAFKG RLDGSIGIGG TTASPKISWQ LGIGTARTDG SLAIASDPAN


 


451
GQRKLVLDTV NIAAGQGSLT AQGYLELFKD RLLKLDIRSR AFDPSRIDPQ


 


501
LPAGNINGSI NLAGELAKEK FTGKMRFLPG TFNGVPIAGS ADIVYESRHL


 


551
PRAAVDLRLG RNIIKTDGGF GKKGDRLNLN ITAPDLSRFG FGLAGSLNVR


 


601
GHLSGDLDGG IRTFETDLSG AARNLHIGKA ADIRSLDFTL KGSPDTSRPI


 


651
RADIKGSRLS LSGGAAVVDT ADLMLDGTGV QHRIRTHAAM TLDGKPFKFD


 


701
LDASGGINRE LTRWKGSIGI LDIGGAFNLK LQNRMTLEAG AERVAASAAN


 


751
WQAMGGSLNL QHFSWDKKTG ISAKGGAHGL HIAELHNFFK PPFEHNLVLN


 


801
GDWDVAYGRN ARGYLNISRQ SGDAVLPGGQ ALGLNAFSLK TRFQNDRIGI


 


851
LLDGGARFGR INADLGIANA FGGNMANAPL GGRITASLPD LGALKPFLPA


 


901
AAQNITGSLN AAAQIGGRVG SPSVNAAVNG SSNYGKINGN ITVGQSRSFD


 


951
TAPLGGRLNL TVADAEVFRN FLPVGQTVKG SLNAAVTLGG SIADPHLGGS


 


1001
INGDKLYYRN QTQGIILDNG SLRSHIAGRK WVIDSLKFRH EGTAELSGTV


 


1051
GMENSGPDVD IGAVFDKYRI LSRPNRRLTV SGNTRLRYSP QKGISVTGMI


 


1101
KTDQGLFGSQ KSSMPSVGDD VVVLGEVKKE AAAPLPVNMN LTLDLNDGIR


 


1151
FAGYGADVTI GGKLTLTAQS GGSVRGVGTV RVIKGRYKAY GQDLDITKGT


 


1201
VSFVGPLNDP NLNIRAERRL SPVGAGVEIL GSLNSPRITL TANEPMSEKD


 


1251
KLSWLILNRA GSGSSGDNAA LSAAAGALLA GQINDRIGLV DDLGFTSKRS


 


1301
RNAQTGELNP AEQVLTVGKQ LTGKLYIGYE YSISSAEQSV KLIYRLTRAI


 


1351
QAVARIGSRS SGGELTYTIR FDRFSGSDKK DSAGNGKGK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m285/g285 96.5% identity in 1389 aa overlap







The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1185>:










a285.seq




1
ATGACCGATA CCGCACCGAC AGATACCGAT CCGACCGAAA ACGGCACGCG


 


51
CAAAATGCCG TCTGAACACC GCCCTACCCC GCCGGCAAAA AAACGCCGCC


 


101
CGCTGCTGAA GCTGTCGGCG GCACTGCTGT CTGTTCTGAT TTTGGCAGTA


 


151
TGTTTCCTCG GCTGGCTCGC CGGCACGGAA GCGGGTTTGC GCTTCGGGCT


 


201
GTACCAAATC CCGTCTTGGT TCGGCGTAAA CATTTCCTCC CAAAACCTCA


 


251
AAGGCACGCT GCTCGACGGC TTCGACGGCG ACAACTGGTC GATAGAAACC


 


301
GAGGGGGCAG ACCTTAAAAT CAGCCGCTTC CGCTTCGCGT GGAAACCGTC


 


351
CGAACTGATG CGCCGCAGCC TGCACATTAC CGAAATTTCC GCCGGCGACA


 


401
TCGCCATCGT TACCAAACCG ACTCCGCCTA AAGAAGAACG CCCGCCGCTC


 


451
AGCCTTCCCG ACAGCATAGA CCTGCCTGCC GCCGTCTATC TCGACCGCTT


 


501
CGAGACGGGC AAAATCAGCA TGGGCAAAGC CTTTGACAAA CAAACCGTCT


 


551
ATCTCGAACG GCTGGATGCT TCATACCGTT ACGACCGCAA AGGACACCGC


 


601
CTCGACCTGA AGGCTGCCGA CACGCCGTGG AGCAGTTCGT CGGGGTCAGC


 


651
CTCGGTCGGC TTGAAAAAAC CGTTTGCCCT CGATACCGCC ATTTACACCA


 


701
AAGGCGGACT CGAAGGCAAA ACCATACACA GTACGGCTCG GCTGAGCGGC


 


751
AGCCTGAAGG ATGTGCGCGC CGAACTGGCG ATCGACGGCG GCAATATCCG


 


801
CCTCTCGGGA AAATCCGTCA TCCACCCGTT TGCCGAATCA TTGGATAAAA


 


851
CATTGGAAGA AGTACTGGTC AAAGGGTTCA ACATCAATCC GTCCGCCTTC


 


901
GTGCCTTCCC TGCCCGATGC CGGGCTGAAT TTCGACCTGA CCGCCATCCC


 


951
GTCGTTTTCA GACGGCATCG CGCTGGAAGG CTCGCTCGAT TTGGAAAACA


 


1001
CCAAAGCCGG CTTTGCCGAC CGCAACGGCA TCCCCGTCCG TCAGGTTTTA


 


1051
GGCAGCTTTG TCATCCGGCA GGACGGCACG GTGCATATCG GCAATACGTC


 


1101
CGTCGCCCTG CTCGGACGGG GCGGCATCAG GCTGTCGGGC AAAATCGACA


 


1151
CCGAAAAAGA CATCCTCGAT TTAAATATAG GCATCAACTC CGTCGGCGCG


 


1201
GAAGACGTAC TGCAAACCGC GTTCAAAGGC AGGTTGGACG GCAGCATCGG


 


1251
CATCGGTGGC ACGACCGCCT CGCCCAAAAT CTCTTGGCAA CTCGGCATCG


 


1301
GCACGGCGCG CACGGACGGC AGCCTCGCCA TTGCAAGCGA CCCCGCAAAC


 


1351
GGACAGCGGA AACTGGTGCT CGACACCGTC AACATCGCCG CCGGGCAAGG


 


1401
CAGCCTGACC GCGCAAGGCT ATCTCGAGCT GTTTAAAGAC CGCCTGCTCA


 


1451
AGCTGGACAT CCGTTCCCGC GCATTCGACC CTTCGCGCAT CGATCCGCAA


 


1501
CTTCCGGCAG GCAATATCAA CGGCTCAATA AACCTTGCCG GCGAACTGGC


 


1551
AAAAGAGAAA TTCACAGGCA AAATGCGGTT TTTACCCGGC ACGTTCAACG


 


1601
GCGTACCGAT TGCCGGCAGT GCCGACATTG TTTACGAGTC CCGCCACCTT


 


1651
CCGCGTGCCG CCGTCGATTT GCGGCTGGGG CGGAACATTA TTAAAACAGA


 


1701
CGGCGGCTTC GGCAAAAAAG GCGACCGGCT TAACCTCAAT ATCACCGCAC


 


1751
CCGATTTATC CCGTTTCGGT TTCGGACTCG CGGGGTCTTT AAATGTACGC


 


1801
GGACACCTTT CCGGCGATTT GGACGGTGGC ATCCGAACCT TTGAAACCGA


 


1851
CCTTTCCGGC GCGGCGCGCA ACCTGCACAT CGGCAAGGCG GCAGACATCC


 


1901
GTTCGCTCGA TTTCACGCTC AAAGGTTCGC CCGACACAAG CCGCCCGATA


 


1951
CGCGCCGACA TCAAAGGCAG CCGCCTTTCG CTGTCGGGCG GAGCGGAGGT


 


2001
TGTCGATACC GCCGACCTGA TGCTGGACGG CACGGGCGTG CAGCACCGCA


 


2051
TCCGCACACA CGCCGCCATG ACGCTGGATG GCAAACCGTT CAAATTCGAT


 


2101
TTGGACGCTT CAGGCGGCAT CAACAGGGAA CTTACCCGAT GGAAAGGCAG


 


2151
CATCGGCATC CTCGACATCG GCGGCGCATT CAACCTCAAG CTGCAAAACC


 


2201
GTATGACGCT CGAAGCCGGT GCGGAACGCG TGGCGGCAAG TGCGGCAAAT


 


2251
TGGCAGGCAA TGGGCGGCAG CCTCAACCTG CAACACTTTT CTTGGGATAA


 


2301
AAAAACCGGC ATATCGGCAA AAGGCGGCGC ACACGGTCTG CATATCGCCG


 


2351
AGTTGCACAA TTTCTTCAAA CCGCCCTTCG AACACAATCT GGTTTTAAAC


 


2401
GGCGACTGGG ATGTCGCCTA CGGGCGAAAC GCGCGCGGCT ACCTCAATAT


 


2451
CAGCCGGCAA AGCGGCGATG CCGTATTGCC CGGCGGGCAG GCTTTGGGTT


 


2501
TGAACGCATT TTCCCTGAAA ACGCGCTTTC AAAACGACCG TATCGGAATC


 


2551
CTGCTTGACG GCGGCGCGCG TTTCGGGCGG ATTAACGCCG ATTTGGACAT


 


2601
CGGCAACGCC TTCGGCGGCA ATATGGCAAA TGCACCGCTC GGCGGCAGGA


 


2651
TTACCGCCTC CCTTCCCGAC TTGGGCACAT TGAAGCCCTT TCTGCCCGCC


 


2701
GCCGCGCAAA ACATTACCGG CAGCCTGAAT GCCGCCGCGC AAATCGGCGG


 


2751
ACGGGTCGGC TCTCCGTCCG TCAATGCCGC CGTCAACGGC AGCAGCAACT


 


2801
ACGGGAAAAT CAACGGCAAC ATCACCGTCG GGCAAAGCCG CTCTTTCGAT


 


2851
ACCGCGCCTT TGGGCGGCAG GCTCAACCTG ACCGTTGCCG ATGCCGAAGT


 


2901
ATTCCGCAAC TTCCTACCGG TCGGACAAAC CGTCAAAGGC AGCCTGAATG


 


2951
CCGCCGTAAC CCTCGGCGGC AGCATCGCCG ATCCGCACTT GGGCGGCAGC


 


3001
ATCAACGGCG ACAAACTCTA TTACCGCAAC CAAACCCAAG GCATCATCTT


 


3051
GGACAACGGC TCGCTGCGTT CGCATATCGC GGGCAGGAAA TGGGTAATCG


 


3101
ACAGCCTGAA ATTCCGGCAC GAAGGGACGG CGGAACTCTC CGGTACGGTC


 


3151
GGTATGGAAA ACAGCGGACC CGATGTCGAT ATCGGCGCGG TGTTCGACAA


 


3201
ATACCGCATC CTGTCCCGCC CCAACCGCCG CCTGACGGTT TCCGGCAACA


 


3251
CCCGCCTGCG CTATTCGCCG CAAAAAGGCA TATCCGTTAC CGGGATGATT


 


3301
AAAACGGATC AGGGGCTGTT CGGTTCGCAA AAATCCTCGA TGCCGTCCGT


 


3351
CGGCGACGAT GTCGTCGTAT TAGGCGAAGT CAAAAAAGAG GCGGCGGCAC


 


3401
CGCTCCCCGT CAATATGAAC CTGACTTTAG ACCTCAATGA CGGCATCCGC


 


3451
TTCGCCGGCT ACGGCGCGGA CGTTACCATA GGCGGCAAAC TGACCCTGAC


 


3501
CGCCCAATCG GGCGGAAGCG TGCGGGGCGT GGGCACGGTC CGCGTCATCA


 


3551
AAGGGCGTTA TAAGGCATAC GGGCAGGATT TGGACATTAC CAAAGGCACG


 


3601
GTCTCCTTTG TCGGCCCGCT CAACGACCCC AACCTCAACA TCCGCGCCGA


 


3651
ACGCCGCCTT TCCCCCGTCG GTGCGGGCGT GGAAATATTG GGCAGCCTCA


 


3701
ACAGTCCGCG CATTACGCTG ACGGCAAACG AACCGATGAG TGAAAAAGAC


 


3751
AAGCTCTCCT GGCTCATCCT CAACCGCGCC GGCAGTGGCA GCAGCGGCGA


 


3801
CAATGCCGCC CTGTCCGCAG CCGCCGGCGC GCTGCTTGCC GGGCAAATCA


 


3851
ACGACCGCAT CGGGCTGGTG GATGATTTGG GCTTTACCAG CAAGCGCAGC


 


3901
CGCAACGCGC AAACCGGCGA ACTCAACCCC GCCGAACAGG TGCTGACCGT


 


3951
CGGCAAACAA CTGACCGGCA AACTCTACAT CGGCTACGAA TACAGCATCT


 


4001
CCAGCGCGGA ACAGTCCGTC AAACTGATTT ACCGGCTGAC CCGCGCCATA


 


4051
CAGGCGGTTG CCCGTATCGG CAGCCGTTCG TCGGGCGGCG AGCTGACATA


 


4101
CACCATACGT TTCGACCGCT TCTCCGGTTC GGACAAAAAA GACTCCGCCG


 


4151
GAAACAGCAA AGGAAAATAA






This corresponds to the amino acid sequence <SEQ ID 1186; ORF 285.a>:










a285.pep




1
MTDTAPTDTD PTENGTRKMP SEHRPTPPAK KRRPLLKLSA ALLSVLILAV


 


51
CFLGWLAGTE AGLRFGLYQI PSWFGVNISS QNLKGTLLDG FDGDNWSIET


 


101
EGADLKISRF RFAWKPSELM RRSLHITEIS AGDIAIVTKP TPPKEERPPL


 


151
SLPDSIDLPA AVYLDRFETG KISMGKAFDK QTVYLERLDA SYRYDRKGHR


 


201
LDLKAADTPW SSSSGSASVG LKKPFALDTA IYTKGGLEGK TIHSTARLSG


 


251
SLKDVRAELA IDGGNIRLSG KSVIHPFAES LDKTLEEVLV KGFNINPSAF


 


301
VPSLPDAGLN FDLTAIPSFS DGIALEGSLD LENTKAGFAD RNGIPVRQVL


 


351
GSFVIRQDGT VHIGNTSVAL LGRGGIRLSG KIDTEKDILD LNIGINSVGA


 


401
EDVLQTAFKG RLDGSIGIGG TTASPKISWQ LGIGTARTDG SLAIASDPAN


 


451
GQRKLVLDTV NIAAGQGSLT AQGYLELFKD RLLKLDIRSR AFDPSRIDPQ


 


501
LPAGNINGSI NLAGELAKEK FTGKMRFLPG TFNGVPIAGS ADIVYESRHL


 


551
PRAAVDLRLG RNIIKTDGGF GKKGDRLNLN ITAPDLSRFG FGLAGSLNVR


 


601
GHLSGDLDGG IRTFETDLSG AARNLHIGKA ADIRSLDFTL KGSPDTSRPI


 


651
RADIKGSRLS LSGGAEVVDT ADLMLDGTGV QHRIRTHAAM TLDGKPFKFD


 


701
LDASGGINRE LTRWKGSIGI LDIGGAFNLK LQNRMTLEAG AERVAASAAN


 


751
WQAMGGSLNL QHFSWDKKTG ISAKGGAHGL HIAELHNFFK PPFEHNLVLN


 


801
GDWDVAYGRN ARGYLNISRQ SGDAVLPGGQ ALGLNAFSLK TRFQNDRIGI


 


851
LLDGGARFGR INADLDIGNA FGGNMANAPL GGRITASLPD LGTLKPFLPA


 


901
AAQNITGSLN AAAQIGGRVG SPSVNAAVNG SSNYGKINGN ITVGQSRSFD


 


951
TAPLGGRLNL TVADAEVFRN FLPVGQTVKG SLNAAVTLGG SIADPHLGGS


 


1001
INGDKLYYRN QTQGIILDNG SLRSHIAGRK WVIDSLKFRH EGTAELSGTV


 


1051
GMENSGPDVD IGAVFDKYRI LSRPNRRLTV SGNTRLRYSP QKGISVTGMI


 


1101
KTDQGLFGSQ KSSMPSVGDD VVVLGEVKKE AAAPLPVNMN LTLDLNDGIR


 


1151
FAGYGADVTI GGKLTLTAQS GGSVRGVGTV RVIKGRYKAY GQDLDITKGT


 


1201
VSFVGPLNDP NLNIRAERRL SPVGAGVEIL GSLNSPRITL TANEPMSEKD


 


1251
KLSWLILNRA GSGSSGDNAA LSAAAGALLA GQINDRIGLV DDLGFTSKRS


 


1301
RNAQTGELNP AEQVLTVGKQ LTGKLYIGYE YSISSAEQSV KLIYRLTRAI


 


1351
QAVARIGSRS SGGELTYTIR FDRFSGSDKK DSAGNSKGK*






m285/a285 99.4% identity in 1389 aa overlap










The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1187>:










g285-1.seq




1
CTGAAGCTGT CGGCGGCACT GCTGTCTGTC CTGATTTTGG CAGTATGTTT


 


51
CCTCGGCTGG ATCGCCGGTA CGGAAGCAGG TTTGCGCTTC GGGCTGTACC


 


101
AAATCCCGTC CTGGTTCGGC GTAAACATTT CCTCCCAAAA CCTCAAAGGC


 


151
ACACTGCTCG ACGGCTTCGA CGGCGACAAC TGGTCGATAG AAACCGAGGG


 


201
GGCAGACCTT AAAATCAGCC GCTTCCGCTT CGCGTGGAAA CCGTCCGAAC


 


251
TGATGCGCCG CAGCCTGCAC ATCACCGACA TCTCCGCCGG CGACATCGCC


 


301
ATCGTAACCA AACCGACTCC GCCTAAAGAA GAACGCCCGC CTCAAGGCCT


 


351
GCCCGACAGC ATAGACCTGC CCGCCGCCGT CTATCTCGAC CGCTTCGAGA


 


401
CGGGCAAAAT CAGCATGGGC AAAACCTTTG ACAAACAAAC CGTCTATCTC


 


451
GAACGCCTCA ACGCGGCATA CCGTTACGAC CGTAAAGGGC ACCGCCTCGA


 


501
CCTGAAGGCC GCCGACACGC CGTGGAGCAG TTCGTCGGGG TCAGCCTCGG


 


551
TCGGCTTGAA AAAACCGTTT GCCCTCGATA CCGCCATTTA CACCAAAGGC


 


601
GGATTCGAAG GCGAAACCAT ACACAGTACG GCGCGGCTGA GCGGCAGCCT


 


651
GAAGGATGTG CGCGCCGAAC TGACGATCGA CGGCGGCAAT ATCCGCCTCT


 


701
CGGGAAAATC CGTCATCCAC CCGTTTGCCG AATCATTGGA TAAAACATTG


 


751
GAAGAAGTAC TGGTCAAAGG ATTCAACATC AATCCGTCCG CCTTCGTGCC


 


801
TTCCCTGCCC GATGCCGGGC TGAATTTCGA CCTGACCGCC ATCCCGTCGT


 


851
TTTCAGACGG CATCGCGCTG GAAGGCTCGC TCGATTTGGA AAACACCAAA


 


901
GCCGGCTTTG CCGACCGCAA CGGCATCCCC GTCCGTCAGG TTTTGGGCGG


 


951
CTTTGTCATC CGGCAGGACG GCACGGTGCA TATCGGCAAT ACGTCCGCCG


 


1001
CCCTGCTCGG ACGGGGCGGC ATCAGGCTGT CGGGCAAAAT CGACACCGAA


 


1051
AAAGACATCC TTGATTTAAA TATAGGCATC AACTCCGTCG GCGCGGAAGA


 


1101
CGTGCTGCAA ACCGCGTTCA AAGGCAGGTT GGACGGCAGC ATCGGCATCG


 


1151
GCGGCACGAC CGCCTCGCCC AAAATCTCTT GGCAACTCGG CACCGGCACG


 


1201
GCACGCACGG ACGGCAGCCt cgcCATCGCA AGCGAcCCCG CAAACGAACA


 


1251
GCGGAAACTG GTGTTCGACA CCGTCAACAT CTCCGCCGGG GAAGGCAGCC


 


1301
TGACCGCGCA AGGCTATCTC GAGCTGTTTA AAGACCGCCT GCTCAAGCTG


 


1351
GACATCCGTT CCCGCGCATT CGACCCTTCG CGCATCGATC CGCAATTTCC


 


1401
GGCAGGCgat atCAACGGTT CGATTCATCT TGCCGGTGAA CTGGCAAAAG


 


1451
AGAAATTTAC GGGCAAAATG CGTTTTTTGC CCGGTACGTT CAACGGCGTG


 


1501
CCGATTGCCG GCAGCGCCGA CATTGTTTAC GAGTCCCGCC ACCTTCCGCG


 


1551
CGCCGCCGTC GATTTGCGGT TGGGGCGGAA CATCGTCAAA ACAGACGGCG


 


1601
GCTTCGGCAA AAAAGGCGAC CGGCTTAACC TCAATATCAC CGCACCCGAT


 


1651
TTATCCCGTT TCGGTTTCGG ACTCGCGGGG TCTTTAAATG TACGCGGACA


 


1701
CCTTTCCGGC GATTTGGACG GCGGCATCCG AACCTTTGAA ACCGACCTTT


 


1751
CCGGCACGGC GCGCAACTTA CACATCGGCA AAGCGGCAGA CATCCGTTCG


 


1801
CTCGATTTTA CCCTCAAAGG CTCACCCGGC ACAAGCCGCC CGATGCGCGC


 


1851
CGATATCAAG GGCGGCCGCC TTTCCCTGTC GGGCGGCGCG GCGGTTGTCG


 


1901
ATACCGCCGG CCTGACGCTG GAAGGTACGG GCGCGCAGCA CCGCATCCGC


 


1951
ACACACGCCG CCATGACGCT GGACGGCAAA CCGTTCAAAC TCGATTTGGA


 


2001
CGCTTCAGGC GGCATCAACA GGGAACTTAC CCGATGGAAA GGCAGCATCG


 


2051
GCATCCTCGA CATCGGCGGC GCATTCAACC TCAAGCTGCA AAACCGTATG


 


2101
ACGCTCGAAG CCGGTGCGGA ACACGTGGCG GCAAGTGCGG CAAATTGGCA


 


2151
GGCAATGGGC GGCAGCCTCA ACCTGCAACA CTTTTCTTGG GACAGGAAAA


 


2201
CCGGCATATC GGCAAAAGGC GGCGCACGCG GCCTGCACAT CGCCGAGTTG


 


2251
CACAATTTCT TCAAACCGCC CTTCGAACAC AATCTGGTTT TAAACGGCGA


 


2301
CTGGGATGTC GCCTACGGGC ACAACGCGCG CGGCTACCTC AATATCAGCC


 


2351
GGCAAAGCGG CGATGCCGTA TTGCCCGGCG GGCAGGCTTT GGGTTTGAAC


 


2401
GCATTTTCCC TGAAAACGCG CTTTCAAAAC GACCGCATCG GAATCCTGCT


 


2451
TGACGGCGGC GCGCGTTTCG GACGGATTAA CGCCGATTTG GGCATCGGCA


 


2501
ACGCCTTCGG CGGCAATATG GCAAATACAC CGCTCGGCGG CAGGATTACA


 


2551
GCCTCCCTTC CCGACTTGGG CGCATTGAAG CCCTTTCTGC CCGCCGCCGC


 


2601
GCAAAACATT ACCGGCAGCC TGAATGCCTC CGCGCAAATC GGCGGACGGG


 


2651
TAGGCTCTCC GTCCGTCAAT GCCGCCGTCA ACGGTAGCAG CAACTACGGG


 


2701
AAAATCAACG GCAATATCAC CGTCGGGCAA AGCCGCTCCT TCGATACCGC


 


2751
ACCTTTGGGC GGCAGGCTCA ACCTGACCGT TGCCGATGCC GAAGCATTCC


 


2801
GCAACTTCCT ACCGGTCGGA CAAACCGTCA AAGGCAGCCT GAATGCCGCC


 


2851
GTAACCCTCG GCGGCAGCAT CGCCGACCCG CACTTGGGCG GCAGTATCAA


 


2901
CGGCGACAAG CTCTATTACC GCAACCAAAC CCAAGGCATC ATCTTGGACA


 


2951
ACGGCTCGCT GCGTTCGCAT ATTGCAGGCA GGAAATGGGT AATCGACAGC


 


3001
CTGAAATTCC GGCACGAAGG GACGGCGGAA CTCTCCGGCA CGGTCAGCAT


 


3051
GGAAAACAGC GTGCCCGATG TCGATATCGG CGCGGTGTTC GACAAATACC


 


3101
GCATCCTGTC CCGCCCCAAC CGCCGCCTGA CGGTTTCCGG CAACACCCGC


 


3151
CTGCGCTATT CGCCGCAAAA AGGCATATCC GTTACCGGTA TGATTAAAAC


 


3201
TGATCAGGGG CTGTTCGGTT CGCAAAAATC CTCGATGCCG TCCGTCGGCG


 


3251
ACGATGTCGT CGTATTGGGC GAAGTCAAGA AAGAGGCGGC GGCATCGCTC


 


3301
CCCGTCAATA TGAACCTGAC TTTAGACCTC AATGACGGCA TCCGCTTCTC


 


3351
CGGCTACGGC GCGGACGTTA CCATAGGCGG CAAACTGACC CTGACCGCGC


 


3401
AACCGGGCGG AAATGTGCGT GGGGTGGGCA CGGTCCGCGT CATCAAAGGG


 


3451
CGTTACAAAG CATACGGGCA GGATTTAGAC ATTACCAAAG GCACAGTCTC


 


3501
CTTTGTCGGC CCGCTCAACG ACCCCAACCT GAACATCCGC GCCGAACGCC


 


3551
GCCTTTCCCC CGTCGGTGCG GGCGTGGAAA TATTGGGCAG CCTCAACAGC


 


3601
CCGCGCATTA CGCTGACGGC AAACGAACCG ATGAGTGAAA AAGACAAGCT


 


3651
CTCCTGGCTC ATCCTCAACC GTGCCGGCAG CGGCAGCAGC GGCGACAATG


 


3701
CCGCCCTGTC CGCAGCCGCA GGCGCGCTGC TTGCCGGGCA AATCAACGAC


 


3751
CGCATCGGGC TGGTGGATGA TTTGGGCTTT ACCAGCAAGC GCAGCCGCAA


 


3801
CGCGCAAACC GGCGAACTCA ACCCCGCCGA ACAGGTGCTG ACCGTCGGCA


 


3851
AACAACTGAC CGGCAAACTC TACATCGGCT ACGAATACGG CATCTCCAGC


 


3901
GCGGAACAGT CCGTCAAACT GATTTACCGG CTGACCCGCG CCATACAGGC


 


3951
GGTTGCCCGT ATCGGCAGCC GTTCGTCGGG CGGCGAGCTG ACATACACCA


 


4001
TACGTTTCGA CCGCCTCTTC GGTTCGGACA AAAAAGACTC CGCAGGAAAC


 


4051
GGCAAAGGGA AATAA






This corresponds to the amino acid sequence <SEQ ID 1188; ORF 285-1.ng>:










g285-1.pep




1
LKLSAALLSV LILAVCFLGW IAGTEAGLRF GLYQIPSWFG VNISSQNLKG


 


51
TLLDGFDGDN WSIETEGADL KISRFRFAWK PSELMRRSLH ITDISAGDIA


 


101
IVTKPTPPKE ERPPQGLPDS IDLPAAVYLD RFETGKISMG KTFDKQTVYL


 


151
ERLNAAYRYD RKGHRLDLKA ADTPWSSSSG SASVGLKKPF ALDTAIYTKG


 


201
GFEGETIHST ARLSGSLKDV RAELTIDGGN IRLSGKSVIH PFAESLDKTL


 


251
EEVLVKGFNI NPSAFVPSLP DAGLNFDLTA IPSFSDGIAL EGSLDLENTK


 


301
AGFADRNGIP VRQVLGGFVI RQDGTVHIGN TSAALLGRGG IRLSGKIDTE


 


351
KDILDLNIGI NSVGAEDVLQ TAFKGRLDGS IGIGGTTASP KISWQLGTGT


 


401
ARTDGSLAIA SDPANEQRKL VFDTVNISAG EGSLTAQGYL ELFKDRLLKL


 


451
DIRSRAFDPS RIDPQFPAGD INGSIHLAGE LAKEKFTGKM RFLPGTFNGV


 


501
PIAGSADIVY ESRHLPRAAV DLRLGRNIVK TDGGFGKKGD RLNLNITAPD


 


551
LSRFGFGLAG SLNVRGHLSG DLDGGIRTFE TDLSGTARNL HIGKAADIRS


 


601
LDFTLKGSPG TSRPMRADIK GGRLSLSGGA AVVDTAGLTL EGTGAQHRIR


 


651
THAAMTLDGK PFKLDLDASG GINRELTRWK GSIGILDIGG AFNLKLQNRM


 


701
TLEAGAEHVA ASAANWQAMG GSLNLQHFSW DRKTGISAKG GARGLHIAEL


 


751
HNFFKPPFEH NLVLNGDWDV AYGHNARGYL NISRQSGDAV LPGGQALGLN


 


801
AFSLKTRFQN DRIGILLDGG ARFGRINADL GIGNAFGGNM ANTPLGGRIT


 


851
ASLPDLGALK PFLPAAAQNI TGSLNASAQI GGRVGSPSVN AAVNGSSNYG


 


901
KINGNITVGQ SRSFDTAPLG GRLNLTVADA EAFRNFLPVG QTVKGSLNAA


 


951
VTLGGSIADP HLGGSINGDK LYYRNQTQGI ILDNGSLRSH IAGRKWVIDS


 


1001
LKFRHEGTAE LSGTVSMENS VPDVDIGAVF DKYRILSRPN RRLTVSGNTR


 


1051
LRYSPQKGIS VTGMIKTDQG LFGSQKSSMP SVGDDVVVLG EVKKEAAASL


 


1101
PVNMNLTLDL NDGIRFSGYG ADVTIGGKLT LTAQPGGNVR GVGTVRVIKG


 


1151
RYKAYGQDLD ITKGTVSFVG PLNDPNLNIR AERRLSPVGA GVEILGSLNS


 


1201
PRITLTANEP MSEKDKLSWL ILNRAGSGSS GDNAALSAAA GALLAGQIND


 


1251
RIGLVDDLGF TSKRSRNAQT GELNPAEQVL TVGKQLTGKL YIGYEYGISS


 


1301
AEQSVKLIYR LTRAIQAVAR IGSRSSGGEL TYTIRFDRLF GSDKKDSAGN


 


1351
GKGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1189>:










m285-1.seq




1
CTGAAGCTGT CGGCGGCACT GCTGTCTGTC CTGATTTTGG CAGTATGTTT


 


51
CCTCGGCTGG CTCGCCGGTA CGGAAGCAGG TTTGCGCTTC GGGCTGTACC


 


101
AAATCCCGTC TTGGTTCGGC GTAAACATTT CCTCCCAAAA CCTCAAAGGC


 


151
ACGCTGCTCG ACGGCTTCGA CGGCGACAAC TGGTCGATAG AAACCGAGGG


 


201
GGCAGACCTT AAAATCAGCC GCTTCCGCTT CGCGTGGAAA CCGTCCGAAC


 


251
TGATGCGCCG CAGCCTGCAC ATTACCGAAA TTTCCGCCGG CGACATCGCC


 


301
ATCGTTACCA AACCGACTCC GCCTAAAGAA GAACGCCCGC CGCTCAGCCT


 


351
TCCCGACAGC ATAGACCTGC CTGCCGCCGT CTATCTCGAC CGCTTCGAGA


 


401
CGGGCAAAAT CAGCATGGGC AAAGCCTTTG ACAAACAAAC CGTCTATCTC


 


451
GAACGGCTGG ATGCTTCATA CCGTTACGAC CGCAAAGGAC ACCGCCTTGA


 


501
CCTGAAGGCC GCCGACACGC CGTGGAGCAG TTCGTCGGGG GCGGCCTCGG


 


551
TCGGCTTGAA AAAACCGTTT GCCCTCGATA CCGCCATTTA CACCAAAGGC


 


601
GGACTCGAAG GCAAAACCAT ACACAGTACG GCTCGGCTGA GCGGCAGCCT


 


651
GAAGGATGTG CGCGCCGAAC TGGCGATCGA CGGCGGCAAT ATCCGCCTCT


 


701
CGGGAAAATC CGTCATCCAC CCGTTTGCCG AATCATTGGA TAAAACATTG


 


751
GAAGAAGTAC TGGTCAAAGG GTTCAACATC AATCCGGCCG CCTTCGTGCC


 


801
TTCCCTGCCC GATGCCGGAC TGAATTTCGA CCTGACCGCC ATCCCGTCGT


 


851
TTTCAGACGG CATCGCGCTG GAAGGTTCGC TCGATTTGGA AAACACCAAA


 


901
GCCGGCTTTG CCGACCGCAA CGGCATCCCC GTCCGTCAGG TTTTAGGCGG


 


951
CTTTGTCATC CGGCAGGACG GCACGGTGCA TATCGGCAAT ACGTCCGCCG


 


1001
CCCTGCTCGG ACGGGGCGGC ATCAGGCTGT CGGGCAAAAT CGACACCGAA


 


1051
AAAGACATCC TCGATTTAAA TATAGGCATC AACTCCGTCG GCGCGGAAGA


 


1101
CGTACTGCAA ACCGCGTTCA AAGGCAGGTT GGACGGCAGC ATCGGCATCG


 


1151
GTGGCACGAC CGCCTCGCCC AAAATCTCTT GGCAACTCGG CATCGGCACG


 


1201
GCGCGCACGG ACGGCAGCCT CGCCATTGCA AGCGACCCAG CAAACGGACA


 


1251
GCGGAAACTG GTGCTCGACA CCGTCAACAT CGCCGCCGGG CAAGGCAGCC


 


1301
TGACCGCGCA AGGCTATCTC GAGCTGTTTA AAGACCGCCT GCTCAAGCTG


 


1351
GACATCCGTT CCCGCGCATT CGACCCTTCG CGCATCGATC CGCAACTTCC


 


1401
GGCAGGCAAT ATCAACGGCT CAATAAACCT TGCCGGCGAA CTGGCAAAAG


 


1451
AGAAATTCAC AGGCAAAATG CGGTTTTTAC CCGGCACGTT CAACGGCGTA


 


1501
CCGATTGCCG GCAGTGCCGA CATTGTTTAC GAGTCCCGCC ACCTTCCGCG


 


1551
TGCCGCCGTC GATTTGCGGC TGGGGCGGAA CATTATTAAA ACAGACGGCG


 


1601
GCTTCGGCAA AAAAGGCGAC CGGCTTAACC TCAATATCAC CGCACCCGAT


 


1651
TTATCCCGTT TCGGTTTCGG ACTCGCGGGG TCTTTAAATG TACGCGGACA


 


1701
CCTTTCCGGT GATTTGGACG GCGGCATCCG AACCTTTGAA ACCGACCTTT


 


1751
CCGGCGCGGC GCGCAACCTG CACATCGGCA AGGCGGCAGA CATCCGTTCG


 


1801
CTCGATTTCA CGCTCAAAGG TTCGCCCGAC ACAAGCCGCC CGATACGCGC


 


1851
CGACATCAAA GGCAGCCGCC TTTCGCTGTC GGGCGGAGCG GCGGTTGTCG


 


1901
ATACCGCCGA CCTGATGCTG GACGGCACGG GCGTGCAGCA CCGCATCCGC


 


1951
ACACACGCCG CCATGACGCT GGATGGCAAA CCGTTCAAAT TCGATTTGGA


 


2001
CGCTTCAGGC GGCATCAACA GGGAACTTAC CCGATGGAAA GGCAGCATCG


 


2051
GCATCCTCGA CATCGGCGGC GCATTCAACC TCAAGCTGCA AAACCGTATG


 


2101
ACGCTCGAAG CCGGTGCGGA ACGCGTGGCG GCAAGTGCGG CAAATTGGCA


 


2151
GGCAATGGGC GGCAGCCTCA ACCTGCAACA CTTTTCTTGG GATAAAAAAA


 


2201
CCGGCATATC GGCAAAAGGC GGCGCACACG GTCTGCATAT CGCCGAGTTG


 


2251
CACAATTTCT TCAAACCGCC CTTCGAACAC AATCTGGTTT TAAACGGCGA


 


2301
CTGGGATGTC GCCTACGGGC GCAACGCGCG CGGCTACCTC AATATCAGCC


 


2351
GGCAAAGCGG CGATGCCGTA TTGCCCGGCG GGCAGGCTTT GGGTTTGAAC


 


2401
GCATTTTCCC TGAAAACGCG CTTTCAAAAC GACCGCATCG GAATCCTGCT


 


2451
TGACGGCGGC GCGCGTTTCG GGCGGATTAA CGCCGATTTG GGCATCGCCA


 


2501
ACGCCTTCGG CGGCAATATG GCAAATGCAC CGCTCGGCGG CAGGATTACC


 


2551
GCCTCCCTTC CCGACTTGGG CGCATTGAAG CCCTTTCTGC CCGCCGCCGC


 


2601
GCAAAACATT ACCGGCAGCC TGAATGCCGC CGCGCAAATC GGCGGACGGG


 


2651
TAGGCTCTCC GTCCGTCAAT GCCGCCGTCA ACGGCAGCAG CAACTACGGG


 


2701
AAAATCAACG GCAACATCAC CGTCGGGCAA AGCCGCTCTT TCGATACCGC


 


2751
GCCTTTGGGC GGCAGGCTCA ACCTGACCGT TGCCGATGCC GAAGTATTCC


 


2801
GCAACTTCCT ACCGGTCGGA CAAACCGTCA AAGGCAGCCT GAATGCCGCC


 


2851
GTAACCCTCG GCGGCAGCAT CGCCGATCCG CACTTGGGCG GCAGCATCAA


 


2901
CGGCGACAAA CTCTATTACC GCAACCAAAC CCAAGGCATC ATCTTGGACA


 


2951
ACGGCTCGCT GCGTTCGCAT ATCGCGGGCA GGAAATGGGT AATCGACAGC


 


3001
CTGAAATTCC GGCACGAAGG GACGGCGGAA CTCTCCGGTA CGGTCGGTAT


 


3051
GGAAAACAGC GGACCCGATG TCGATATCGG CGCGGTGTTC GACAAATACC


 


3101
GCATCCTGTC CCGCCCCAAC CGCCGCCTGA CGGTTTCCGG CAACACCCGC


 


3151
CTGCGCTATT CGCCGCAAAA AGGCATATCC GTTACCGGGA TGATTAAAAC


 


3201
GGATCAGGGG CTGTTCGGTT CGCAAAAATC CTCGATGCCG TCCGTCGGCG


 


3251
ACGATGTCGT CGTATTAGGC GAAGTCAAAA AAGAGGCGGC GGCACCGCTC


 


3301
CCCGTCAATA TGAACCTGAC TTTAGACCTC AATGACGGCA TCCGCTTCGC


 


3351
CGGCTACGGC GCGGACGTTA CCATAGGCGG CAAACTGACC CTGACCGCCC


 


3401
AATCGGGCGG AAGCGTACGG GGCGTGGGCA CGGTCCGCGT CATCAAAGGG


 


3451
CGTTATAAGG CATACGGGCA GGATTTGGAC ATTACCAAAG GCACGGTCTC


 


3501
CTTTGTCGGC CCGCTCAACG ATCCCAACCT CAACATCCGC GCCGAACGCC


 


3551
GCCTTTCCCC CGTCGGTGCG GGCGTGGAAA TATTGGGCAG CCTCAACAGC


 


3601
CCGCGCATTA CGCTGACGGC AAACGAACCG ATGAGTGAAA AAGACAAGCT


 


3651
CTCTTGGCTC ATCCTCAACC GCGCCGGCAG CGGCAGCAGC GGCGACAATG


 


3701
CCGCCCTGTC TGCAGCCGCA GGTGCGCTGC TTGCCGGGCA AATCAACGAC


 


3751
CGCATCGGGC TGGTGGATGA TTTGGGCTTT ACCAGCAAGC GCAGCCGCAA


 


3801
CGCGCAAACC GGCGAACTCA ACCCCGCCGA ACAGGTGCTG ACCGTCGGCA


 


3851
AACAACTGAC CGGCAAACTC TACATCGGCT ACGAATACAG CATCTCCAGC


 


3901
GCGGAACAGT CCGTCAAACT GATTTACCGG CTGACCCGCG CCATACAGGC


 


3951
GGTTGCCCGT ATCGGCAGCC GTTCGTCGGG CGGCGAGCTG ACATACACCA


 


4001
TACGTTTCGA CCGCTTCTCC GGTTCGGACA AAAAAGACTC CGCCGGAAAC


 


4051
GGCAAAGGAA AATAA






This corresponds to the amino acid sequence <SEQ ID 1190; ORF 285-1>:










m285-1.pep




1
LKLSAALLSV LILAVCFLGW LAGTEAGLRF GLYQIPSWFG VNISSQNLKG


 


51
TLLDGFDGDN WSIETEGADL KISRFRFAWK PSELMRRSLH ITEISAGDIA


 


101
IVTKPTPPKE ERPPLSLPDS IDLPAAVYLD RFETGKISMG KAFDKQTVYL


 


151
ERLDASYRYD RKGHRLDLKA ADTPWSSSSG AASVGLKKPF ALDTAIYTKG


 


201
GLEGKTIHST ARLSGSLKDV RAELAIDGGN IRLSGKSVIH PFAESLDKTL


 


251
EEVLVKGFNI NPAAFVPSLP DAGLNFDLTA IPSFSDGIAL EGSLDLENTK


 


301
AGFADRNGIP VRQVLGGFVI RQDGTVHIGN TSAALLGRGG IRLSGKIDTE


 


351
KDILDLNIGI NSVGAEDVLQ TAFKGRLDGS IGIGGTTASP KISWQLGIGT


 


401
ARTDGSLAIA SDPANGQRKL VLDTVNIAAG QGSLTAQGYL ELFKDRLLKL


 


451
DIRSRAFDPS RIDPQLPAGN INGSINLAGE LAKEKFTGKM RFLPGTFNGV


 


501
PIAGSADIVY ESRHLPRAAV DLRLGRNIIK TDGGFGKKGD RLNLNITAPD


 


551
LSRFGFGLAG SLNVRGHLSG DLDGGIRTFE TDLSGAARNL HIGKAADIRS


 


601
LDFTLKGSPD TSRPIRADIK GSRLSLSGGA AVVDTADLML DGTGVQHRIR


 


651
THAAMTLDGK PFKFDLDASG GINRELTRWK GSIGILDIGG AFNLKLQNRM


 


701
TLEAGAERVA ASAANWQAMG GSLNLQHFSW DKKTGISAKG GAHGLHIAEL


 


751
HNFFKPPFEH NLVLNGDWDV AYGRNARGYL NISRQSGDAV LPGGQALGLN


 


801
AFSLKTRFQN DRIGILLDGG ARFGRINADL GIANAFGGNM ANAPLGGRIT


 


851
ASLPDLGALK PFLPAAAQNI TGSLNAAAQI GGRVGSPSVN AAVNGSSNYG


 


901
KINGNITVGQ SRSFDTAPLG GRLNLTVADA EVFRNFLPVG QTVKGSLNAA


 


951
VTLGGSIADP HLGGSINGDK LYYRNQTQGI ILDNGSLRSH IAGRKWVIDS


 


1001
LKFRHEGTAE LSGTVGMENS GPDVDIGAVF DKYRILSRPN RRLTVSGNTR


 


1051
LRYSPQKGIS VTGMIKTDQG LFGSQKSSMP SVGDDVVVLG EVKKEAAAPL


 


1101
PVNMNLTLDL NDGIRFAGYG ADVTIGGKLT LTAQSGGSVR GVGTVRVIKG


 


1151
RYKAYGQDLD ITKGTVSFVG PLNDPNLNIR AERRLSPVGA GVEILGSLNS


 


1201
PRITLTANEP MSEKDKLSWL ILNRAGSGSS GDNAALSAAA GALLAGQIND


 


1251
RIGLVDDLGF TSKRSRNAQT GELNPAEQVL TVGKQLTGKL YIGYEYSISS


 


1301
AEQSVKLIYR LTRAIQAVAR IGSRSSGGEL TYTIRFDRFS GSDKKDSAGN


 


1351
GKGK*









g285-1/m285-1 96.5% identity in 1354 aa overlap








The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1191>:










a285-1.seq




1
CTGAAGCTGT CGGCGGCACT GCTGTCTGTT CTGATTTTGG CAGTATGTTT


 


51
CCTCGGCTGG CTCGCCGGCA CGGAAGCGGG TTTGCGCTTC GGGCTGTACC


 


101
AAATCCCGTC TTGGTTCGGC GTAAACATTT CCTCCCAAAA CCTCAAAGGC


 


151
ACGCTGCTCG ACGGCTTCGA CGGCGACAAC TGGTCGATAG AAACCGAGGG


 


201
GGCAGACCTT AAAATCAGCC GCTTCCGCTT CGCGTGGAAA CCGTCCGAAC


 


251
TGATGCGCCG CAGCCTGCAC ATTACCGAAA TTTCCGCCGG CGACATCGCC


 


301
ATCGTTACCA AACCGACTCC GCCTAAAGAA GAACGCCCGC CGCTCAGCCT


 


351
TCCCGACAGC ATAGACCTGC CTGCCGCCGT CTATCTCGAC CGCTTCGAGA


 


401
CGGGCAAAAT CAGCATGGGC AAAGCCTTTG ACAAACAAAC CGTCTATCTC


 


451
GAACGGCTGG ATGCTTCATA CCGTTACGAC CGCAAAGGAC ACCGCCTCGA


 


501
CCTGAAGGCT GCCGACACGC CGTGGAGCAG TTCGTCGGGG TCAGCCTCGG


 


551
TCGGCTTGAA AAAACCGTTT GCCCTCGATA CCGCCATTTA CACCAAAGGC


 


601
GGACTCGAAG GCAAAACCAT ACACAGTACG GCTCGGCTGA GCGGCAGCCT


 


651
GAAGGATGTG CGCGCCGAAC TGGCGATCGA CGGCGGCAAT ATCCGCCTCT


 


701
CGGGAAAATC CGTCATCCAC CCGTTTGCCG AATCATTGGA TAAAACATTG


 


751
GAAGAAGTAC TGGTCAAAGG GTTCAACATC AATCCGTCCG CCTTCGTGCC


 


801
TTCCCTGCCC GATGCCGGGC TGAATTTCGA CCTGACCGCC ATCCCGTCGT


 


851
TTTCAGACGG CATCGCGCTG GAAGGCTCGC TCGATTTGGA AAACACCAAA


 


901
GCCGGCTTTG CCGACCGCAA CGGCATCCCC GTCCGTCAGG TTTTAGGCAG


 


951
CTTTGTCATC CGGCAGGACG GCACGGTGCA TATCGGCAAT ACGTCCGTCG


 


1001
CCCTGCTCGG ACGGGGCGGC ATCAGGCTGT CGGGCAAAAT CGACACCGAA


 


1051
AAAGACATCC TCGATTTAAA TATAGGCATC AACTCCGTCG GCGCGGAAGA


 


1101
CGTACTGCAA ACCGCGTTCA AAGGCAGGTT GGACGGCAGC ATCGGCATCG


 


1151
GTGGCACGAC CGCCTCGCCC AAAATCTCTT GGCAACTCGG CATCGGCACG


 


1201
GCGCGCACGG ACGGCAGCCT CGCCATTGCA AGCGACCCCG CAAACGGACA


 


1251
GCGGAAACTG GTGCTCGACA CCGTCAACAT CGCCGCCGGG CAAGGCAGCC


 


1301
TGACCGCGCA AGGCTATCTC GAGCTGTTTA AAGACCGCCT GCTCAAGCTG


 


1351
GACATCCGTT CCCGCGCATT CGACCCTTCG CGCATCGATC CGCAACTTCC


 


1401
GGCAGGCAAT ATCAACGGCT CAATAAACCT TGCCGGCGAA CTGGCAAAAG


 


1451
AGAAATTCAC AGGCAAAATG CGGTTTTTAC CCGGCACGTT CAACGGCGTA


 


1501
CCGATTGCCG GCAGTGCCGA CATTGTTTAC GAGTCCCGCC ACCTTCCGCG


 


1551
TGCCGCCGTC GATTTGCGGC TGGGGCGGAA CATTATTAAA ACAGACGGCG


 


1601
GCTTCGGCAA AAAAGGCGAC CGGCTTAACC TCAATATCAC CGCACCCGAT


 


1651
TTATCCCGTT TCGGTTTCGG ACTCGCGGGG TCTTTAAATG TACGCGGACA


 


1701
CCTTTCCGGC GATTTGGACG GTGGCATCCG AACCTTTGAA ACCGACCTTT


 


1751
CCGGCGCGGC GCGCAACCTG CACATCGGCA AGGCGGCAGA CATCCGTTCG


 


1801
CTCGATTTCA CGCTCAAAGG TTCGCCCGAC ACAAGCCGCC CGATACGCGC


 


1851
CGACATCAAA GGCAGCCGCC TTTCGCTGTC GGGCGGAGCG GAGGTTGTCG


 


1901
ATACCGCCGA CCTGATGCTG GACGGCACGG GCGTGCAGCA CCGCATCCGC


 


1951
ACACACGCCG CCATGACGCT GGATGGCAAA CCGTTCAAAT TCGATTTGGA


 


2001
CGCTTCAGGC GGCATCAACA GGGAACTTAC CCGATGGAAA GGCAGCATCG


 


2051
GCATCCTCGA CATCGGCGGC GCATTCAACC TCAAGCTGCA AAACCGTATG


 


2101
ACGCTCGAAG CCGGTGCGGA ACGCGTGGCG GCAAGTGCGG CAAATTGGCA


 


2151
GGCAATGGGC GGCAGCCTCA ACCTGCAACA CTTTTCTTGG GATAAAAAAA


 


2201
CCGGCATATC GGCAAAAGGC GGCGCACACG GTCTGCATAT CGCCGAGTTG


 


2251
CACAATTTCT TCAAACCGCC CTTCGAACAC AATCTGGTTT TAAACGGCGA


 


2301
CTGGGATGTC GCCTACGGGC GAAACGCGCG CGGCTACCTC AATATCAGCC


 


2351
GGCAAAGCGG CGATGCCGTA TTGCCCGGCG GGCAGGCTTT GGGTTTGAAC


 


2401
GCATTTTCCC TGAAAACGCG CTTTCAAAAC GACCGTATCG GAATCCTGCT


 


2451
TGACGGCGGC GCGCGTTTCG GGCGGATTAA CGCCGATTTG GACATCGGCA


 


2501
ACGCCTTCGG CGGCAATATG GCAAATGCAC CGCTCGGCGG CAGGATTACC


 


2551
GCCTCCCTTC CCGACTTGGG CACATTGAAG CCCTTTCTGC CCGCCGCCGC


 


2601
GCAAAACATT ACCGGCAGCC TGAATGCCGC CGCGCAAATC GGCGGACGGG


 


2651
TCGGCTCTCC GTCCGTCAAT GCCGCCGTCA ACGGCAGCAG CAACTACGGG


 


2701
AAAATCAACG GCAACATCAC CGTCGGGCAA AGCCGCTCTT TCGATACCGC


 


2751
GCCTTTGGGC GGCAGGCTCA ACCTGACCGT TGCCGATGCC GAAGTATTCC


 


2801
GCAACTTCCT ACCGGTCGGA CAAACCGTCA AAGGCAGCCT GAATGCCGCC


 


2851
GTAACCCTCG GCGGCAGCAT CGCCGATCCG CACTTGGGCG GCAGCATCAA


 


2901
CGGCGACAAA CTCTATTACC GCAACCAAAC CCAAGGCATC ATCTTGGACA


 


2951
ACGGCTCGCT GCGTTCGCAT ATCGCGGGCA GGAAATGGGT AATCGACAGC


 


3001
CTGAAATTCC GGCACGAAGG GACGGCGGAA CTCTCCGGTA CGGTCGGTAT


 


3051
GGAAAACAGC GGACCCGATG TCGATATCGG CGCGGTGTTC GACAAATACC


 


3101
GCATCCTGTC CCGCCCCAAC CGCCGCCTGA CGGTTTCCGG CAACACCCGC


 


3151
CTGCGCTATT CGCCGCAAAA AGGCATATCC GTTACCGGGA TGATTAAAAC


 


3201
GGATCAGGGG CTGTTCGGTT CGCAAAAATC CTCGATGCCG TCCGTCGGCG


 


3251
ACGATGTCGT CGTATTAGGC GAAGTCAAAA AAGAGGCGGC GGCACCGCTC


 


3301
CCCGTCAATA TGAACCTGAC TTTAGACCTC AATGACGGCA TCCGCTTCGC


 


3351
CGGCTACGGC GCGGACGTTA CCATAGGCGG CAAACTGACC CTGACCGCCC


 


3401
AATCGGGCGG AAGCGTGCGG GGCGTGGGCA CGGTCCGCGT CATCAAAGGG


 


3451
CGTTATAAGG CATACGGGCA GGATTTGGAC ATTACCAAAG GCACGGTCTC


 


3501
CTTTGTCGGC CCGCTCAACG ACCCCAACCT CAACATCCGC GCCGAACGCC


 


3551
GCCTTTCCCC CGTCGGTGCG GGCGTGGAAA TATTGGGCAG CCTCAACAGT


 


3601
CCGCGCATTA CGCTGACGGC AAACGAACCG ATGAGTGAAA AAGACAAGCT


 


3651
CTCCTGGCTC ATCCTCAACC GCGCCGGCAG TGGCAGCAGC GGCGACAATG


 


3701
CCGCCCTGTC CGCAGCCGCC GGCGCGCTGC TTGCCGGGCA AATCAACGAC


 


3751
CGCATCGGGC TGGTGGATGA TTTGGGCTTT ACCAGCAAGC GCAGCCGCAA


 


3801
CGCGCAAACC GGCGAACTCA ACCCCGCCGA ACAGGTGCTG ACCGTCGGCA


 


3851
AACAACTGAC CGGCAAACTC TACATCGGCT ACGAATACAG CATCTCCAGC


 


3901
GCGGAACAGT CCGTCAAACT GATTTACCGG CTGACCCGCG CCATACAGGC


 


3951
GGTTGCCCGT ATCGGCAGCC GTTCGTCGGG CGGCGAGCTG ACATACACCA


 


4001
TACGTTTCGA CCGCTTCTCC GGTTCGGACA AAAAAGACTC CGCCGGAAAC


 


4051
AGCAAAGGAA AATAA






This corresponds to the amino acid sequence <SEQ ID 1192; ORF 285-1.a>:










a285-1.pep




1
LKLSAALLSV LILAVCFLGW LAGTEAGLRF GLYQIPSWFG VNISSQNLKG


 


51
TLLDGFDGDN WSIETEGADL KISRFRFAWK PSELMRRSLH ITEISAGDIA


 


101
IVTKPTPPKE ERPPLSLPDS IDLPAAVYLD RFETGKISMG KAFDKQTVYL


 


151
ERLDASYRYD RKGHRLDLKA ADTPWSSSSG SASVGLKKPF ALDTAIYTKG


 


201
GLEGKTIHST ARLSGSLKDV RAELAIDGGN IRLSGKSVIH PFAESLDKTL


 


251
EEVLVKGFNI NPSAFVPSLP DAGLNFDLTA IPSFSDGIAL EGSLDLENTK


 


301
AGFADRNGIP VRQVLGSFVI RQDGTVHIGN TSVALLGRGG IRLSGKIDTE


 


351
KDILDLNIGI NSVGAEDVLQ TAFKGRLDGS IGIGGTTASP KISWQLGIGT


 


401
ARTDGSLAIA SDPANGQRKL VLDTVNIAAG QGSLTAQGYL ELFKDRLLKL


 


451
DIRSRAFDPS RIDPQLPAGN INGSINLAGE LAKEKFTGKM RFLPGTFNGV


 


501
PIAGSADIVY ESRHLPRAAV DLRLGRNIIK TDGGFGKKGD RLNLNITAPD


 


551
LSRFGFGLAG SLNVRGHLSG DLDGGIRTFE TDLSGAARNL HIGKAADIRS


 


601
LDFTLKGSPD TSRPIRADIK GSRLSLSGGA EVVDTADLML DGTGVQHRIR


 


651
THAAMTLDGK PFKFDLDASG GINRELTRWK GSIGILDIGG AFNLKLQNRM


 


701
TLEAGAERVA ASAANWQAMG GSLNLQHFSW DKKTGISAKG GAHGLHIAEL


 


751
HNFFKPPFEH NLVLNGDWDV AYGRNARGYL NISRQSGDAV LPGGQALGLN


 


801
AFSLKTRFQN DRIGILLDGG ARFGRINADL DIGNAFGGNM ANAPLGGRIT


 


851
ASLPDLGTLK PFLPAAAQNI TGSLNAAAQI GGRVGSPSVN AAVNGSSNYG


 


901
KINGNITVGQ SRSFDTAPLG GRLNLTVADA EVFRNFLPVG QTVKGSLNAA


 


951
VTLGGSIADP HLGGSINGDK LYYRNQTQGI ILDNGSLRSH IAGRKWVIDS


 


1001
LKFRHEGTAE LSGTVGMENS GPDVDIGAVF DKYRILSRPN RRLTVSGNTR


 


1051
LRYSPQKGIS VTGMIKTDQG LFGSQKSSMP SVGDDVVVLG EVKKEAAAPL


 


1101
PVNMNLTLDL NDGIRFAGYG ADVTIGGKLT LTAQSGGSVR GVGTVRVIKG


 


1151
RYKAYGQDLD ITKGTVSFVG PLNDPNLNIR AERRLSPVGA GVEILGSLNS


 


1201
PRITLTANEP MSEKDKLSWL ILNRAGSGSS GDNAALSAAA GALLAGQIND


 


1251
RIGLVDDLGF TSKRSRNAQT GELNPAEQVL TVGKQLTGKL YIGYEYSISS


 


1301
AEQSVKLIYR LTRAIQAVAR IGSRSSGGEL TYTIRFDRFS GSDKKDSAGN


 


1351
SKGK*






a285-1/m285-1 99.3% identity in 1354 aa overlap








The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1193>:










g286.seq




1
atgcagaaca ccggtaccat gatgatcaaa ccgaccgccc tgctcctgcc


 


51
ggctttattt ttctttccgc acgcatacgc gcctgccgcc gacctttccg


 


101
aaaacaaggc ggcgggtttc gcattgttca aaagcaaaag ccccgacacc


 


151
gaatcagtca aattaaaacc caaattcccc gtccgcatcg acacgcagga


 


201
cagtgaaatc aaagatatgg tcgaagaaca cctgccgctc atcacgcagc


 


251
agcaggaaga ggttttggat aaggaacaga cgggattcct tgccgaagaa


 


301
gcaccggaca acgttaaaac aatgctccgc agcaaaggct atttcagcag


 


351
caaggtcagc ctgacggaaa aagacggagc ttatacggtg cacatcacac


 


401
cgggcccgcg caccaaaatc gccaacgtcg gcgtcgccat cctcggcgac


 


451
atcctttcag acggcaacct cgccgaatac taccgcaacg cgctggaaaa


 


501
ctggcagcag ccggtaggca gcgatttcga tcaggacagt tgggaaaaca


 


551
gcaaaacttc cgtcctcggc gcggtaacgc gcaaaggcta cccgcttgcc


 


601
aagctcggca acacccgggc ggccgtcaac cccgataccg ccaccgccga


 


651
tttgaacgtc gtcgtggaca gcggccgccc cattgccttc ggcgactttg


 


701
aaatcaccgg cacacagcgt taccccgaac aaaccgtctc cggcctggcg


 


751
cgcttccaac cgggcacgcc ctacgacctc gacctgctgc tcgacttcca


 


801
acaggcgctc gaacaaaacg ggcattattc cggcgcgtcc gtacaagccg


 


851
acttcgaccg cctcccaagg ggaccgcgtc cccgtcaaag tcagcgtaac


 


901
cgaggtcaaa cgccacaaac tcgaaaccgg catccgcctc gattcggaat


 


951
acggtttggg cggcaaaatc gcctacgact attacaacct cttcaacaaa


 


1001
ggctatatcg gctcggtcgt ctgggatatg gacaaatacg aaaccacgct


 


1051
tgccgccggc atcagccagc cgcgcaacta tcggggcaac tactggacaa


 


1101
gcaacgtttc ctacaaccgt tcgaccaccc aaaacctcga aaaacgcgcc


 


1151
ttctccggcg gcatctggta tgtgcgcgac cgcgcgggca tcgatgccag


 


1201
gctgggggcg gaatttctcg cagaaggccg gaaaatcccc ggctcggatg


 


1251
tcgatttggg caacagccac gccacgatgc tgaccgcctc ttggaaacgc


 


1301
cagctgctca acaacgtgct gcaccccgaa aacggccatt acctcgacgg


 


1351
caaaatcggg acgactttgg gcacattcct gtcctccacc gcgctaatcc


 


1401
gcacctctgc ccgcgcaggt tatttcttca cgcccgaaaa caaaaaactc


 


1451
ggcacgttca tcatacgcgg acaagcgggt tacaccgttg cacgcgacaa


 


1501
tgccgatgtc ccctcggggc tgatgttccg cagcggcggc gcgtcttccg


 


1551
tgcgcggtta cgaacttga






This corresponds to the amino acid sequence <SEQ ID 1194; ORF 286.ng>:










g286.pep




1
MQNTGTMMIK PTALLLPALF FFPHAYAPAA DLSENKAAGF ALFKSKSPDT


 


51
ESVKLKPKFP VRIDTQDSEI KDMVEEHLPL ITQQQEEVLD KEQTGFLAEE


 


101
APDNVKTMLR SKGYFSSKVS LTEKDGAYTV HITPGPRTKI ANVGVAILGD


 


151
ILSDGNLAEY YRNALENWQQ PVGSDFDQDS WENSKTSVLG AVTRKGYPLA


 


201
KLGNTRAAVN PDTATADLNV VVDSGRPIAF GDFEITGTQR YPEQTVSGLA


 


251
RFQPGTPYDL DLLLDFQQAL EQNGHYSGAS VQADFDRLPR GPRPRQSQRN


 


301
RGQTPQTRNR HPPRFGIRFG RQNRLRLLQP LQQRLYRLGR LGYGQIRNHA


 


351
CRRHQPAAQL SGQLLDKQRF LQPFDHPKPR KTRLLRRHLV CARPRGHRCQ


 


401
AGGGISRRRP ENPRLGCRFG QQPRHDADRL LETPAAQQRA APRKRPLPRR


 


451
QNRDDFGHIP VLHRANPHLC PRRLFLHARK QKTRHVHHTR TSGLHRCTRQ


 


501
CRCPLGADVP QRRRVFRARL RT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1195>:










m286.seq




1
ATGCACGACA CCCGTACCAT GATGATCAAA CCGACCGCCC TGCTCCTGCC


 


51
GGCTTTATTT TTCTTTCCGC ACGCATACGC GCCTGCCGCC GACCTTTCCG


 


101
AAAACAAGGC GGCGGGTTTC GCATTGTTCA AAAACAAAAG CCCCGACACC


 


151
GAATCAGTCA AATTAAAACC CAAATTCCCC GTCCTCATCG ACACGCAGGA


 


201
CAGTGAAATC AAAGATATGG TCGAAGAACA CCTGCCGCTC ATCACGCAGC


 


251
AGCAGGAAGA AGTATTGGAC AAGGAACAGA CGGGCTTCCT CGCCGAAGAA


 


301
GCGCCGGACA ACGTTAAAAC GATGCTCCGC AGCAAAGGCT ATTTCAGCAG


 


351
CAAAGTCAGC CTGACGGAAA AAGACGGAGC TTATACGGTA CACATCACAC


 


401
CGGGCCCGCG CACCAAAATC GCCAACGTCG GCGTCGCCAT CCTCGGCGAC


 


451
ATCCTTTCAG ACGGCAACCT CGCCGAATAC TACCGCAACG CGCTGGAAAA


 


501
CTGGCAGCAG CCGGTAGGCA GCGATTTCGA TCAGGACAGT TGGGAAAACA


 


551
GCAAAACTTC CGTCCTCGGC GCGGTAACGC GCAAAGCCTA CCCGCTTGCC


 


601
AAGCTCGGCA ATACGCAGGC GGCCGTCAAC CCCGATACCG CCACCGCCGA


 


651
TTTGAACGTC GTCGTGGACA GCGGCCGCCC CATCGCCTTC GGCGACTTTG


 


701
AAATCACCGG CACACAGCGT TACCCCGAAC AAATCGTCTC CGGCCTTGCG


 


751
CGTTTCCAGC CCGGTATGCC GTACGACCTC GACCTGCTGC TCGACTTCCA


 


801
ACAGGCGCTC GAACAAAACG GGCATTATTC CGGCGCGTCC GTACAAGCCG


 


851
ACTTCGACCG CCTCCAAGGC GACCGCGTCC CCGTCAAAGT CAGCGTAACC


 


901
GAGGTCAAAC GCCACAAACT CGAAACCGGC ATCCGCCTCG ATTCGGAATA


 


951
CGGTTTGGGC GGCAAAATCG CCTACGACTA TTACAACCTC TTCAACAAAG


 


1001
GCTATATCGG TTCGGTCGTC TGGGATATGG ACAAATACGA AACCACGCTT


 


1051
GCCGCCGGCA TCAGCCAGCC GCGCAACTAT CGGGGCAACT ACTGGACAAG


 


1101
CAACGTTTCC TACAACCGTT CGACCACCCA AAACCTCGAA AAACGCGCCT


 


1151
TCTCCGGCGG CGTCTGGTAT GTGCGCGACC GCGCGGGCAT CGATGCCAGG


 


1201
CTGGGGGCGG AATTTCTCGC AGAAGGCCGG AAAATCCCCG GCTCGGCTGT


 


1251
CGATTTGGGC AACAGCCACG CCACGATGCT GACCGCCTCT TGGAAACGCC


 


1301
AGCTGCTCAA CAACGTGCTG CATCCCGAAA ACGGCCATTA CCTCGACGGC


 


1351
AAAATCGGTA CGACTTTGGG CACATTCCTG TCCTCCACCG CGCTGATCCG


 


1401
CACCTCTGCC CGTGCAGGTT ATTTCTTCAC GCCCGAAAAC AAAAAACTCG


 


1451
GCACGTTCAT CATACGCGGA CAAGCGGGTT ACACCGTTGC CCGCGACAAT


 


1501
GCCGACGTTC CTTCAGGGCT GATGTTCCGC AGCGGCGGCG CGTCTTCCGT


 


1551
GCGCGGTTAC GAACTCGACA GCATCGGACT TGCCGGCCCG AACGGATCGG


 


1601
TCCTGCCCGA ACGCGCCCTC CTGGTGGGCA GCCTGGAATA CCAACTGCCG


 


1651
TTTACGCGCA CCCTTTCCGG CGCGGTGTTC CACGATATGG GCGATGCCGC


 


1701
CGCCAATTTC AAACGTATGA AGCTGAAACA CGGTTCGGGA CTGGGCGTGC


 


1751
GCTGGTTCAG CCCGCTTGCG CCGTTTTCCT TCGACATCGC CTACGGGCAC


 


1801
AGCGATAAGA AAATCCGCTG GCACATCAGC TTGGGAACGC GCTTCTAA






This corresponds to the amino acid sequence <SEQ ID 1196; ORF 286>:










m286.pep




1
MHDTRTMMIK PTALLLPALF FFPHAYAPAA DLSENKAAGF ALFKNKSPDT


 


51
ESVKLKPKFP VLIDTQDSEI KDMVEEHLPL ITQQQEEVLD KEQTGFLAEE


 


101
APDNVKTMLR SKGYFSSKVS LTEKDGAYTV HITPGPRTKI ANVGVAILGD


 


151
ILSDGNLAEY YRNALENWQQ PVGSDFDQDS WENSKTSVLG AVTRKAYPLA


 


201
KLGNTQAAVN PDTATADLNV VVDSGRPIAF GDFEITGTQR YPEQIVSGLA


 


251
RFQPGMPYDL DLLLDFQQAL EQNGHYSGAS VQADFDRLQG DRVPVKVSVT


 


301
EVKRHKLETG IRLDSEYGLG GKIAYDYYNL FNKGYIGSVV WDMDKYETTL


 


351
AAGISQPRNY RGNYWTSNVS YNRSTTQNLE KRAFSGGVWY VRDRAGIDAR


 


401
LGAEFLAEGR KIPGSAVDLG NSHATMLTAS WKRQLLNNVL HPENGHYLDG


 


451
KIGTTLGTFL SSTALIRTSA RAGYFFTPEN KKLGTFIIRG QAGYTVARDN


 


501
ADVPSGLMFR SGGASSVRGY ELDSIGLAGP NGSVLPERAL LVGSLEYQLP


 


551
FTRTLSGAVF HDMGDAAANF KRMKLKHGSG LGVRWFSPLA PFSFDIAYGH


 


601
SDKKIRWHIS LGTRF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m286/g286 95.9% identity in 293 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1197>:










a286.seq




1
ATGCACGACA CCCGTACCAT GATGATTAAA CCGACCGCCC TGCTCCTGCC


 


51
GGCTTTATTT TTCTTTCCGC ACGCATACGC GCCTGCCGCC GACCTTTCCG


 


101
AAAACAAGGC GGCGGGTTTC GCATTGTTCA AAAACAAAAG CCCCGACACC


 


151
GAATCAGTTA AATTAAAACC CAAATTCCCC GTCCGCATCG ACACGCAGGA


 


201
TAGTGAAATC AAAGATATGG TCGAAGAACA CCTGCCGCTC ATCACGCAGC


 


251
AGCAGGAAGA AGTATTGGAC AAGGAACAGA CGGGCTTCCT CGCCGAAGAA


 


301
GCACCGGACA ACGTTAAAAC AATGCTCCGC AGCAAAGGCT ATTTCAGCAG


 


351
CAAAGTCAGC CTGACGGAAA AAGACGGAGC TTATACGGTA CACATCACAC


 


401
CGGGCCCGCG CACCAAAATC GCCAACGTCG GCGTCGCCAT CCTCGGCGAC


 


451
ATCCTTTCAG ACGGCAACCT CGCCGAATAC TACCGCAACG CGCTGGAAAA


 


501
CTGGCAGCAG CCGGTAGGCA GTGATTTCGA TCAGGACAGT TGGGAAAACA


 


551
GCAAAACTTC CGTCCTCGGC GCGGTAACGC GCAAAGCCTA CCCGCTTGCC


 


601
AAGCTCGGCA ACACCCGGGC GGCCGTCAAC CCCGATACCG CCACCGCCGA


 


651
TTTGAACGTC GTCGTGGACA GCGGCCGCCC CATCGCCTTC GGCGACTTTG


 


701
AAATTACCGG CACGCAGCGT TACCCCGAAC AAATCGTCTC CGGCTTGGCG


 


751
CGCTTCCAAC CGGGCACGCC CTACGACCTC GACCTGCTGC TCGACTTCCA


 


801
ACAGGCGCTC GAACAAAACG GGCATTATTC CGGCGCGTCC GTACAAGCCG


 


851
ACTTCGACCG CCTCCAAGGC GACCGCGTCC CCGTCAAAGT CAGCGTAACC


 


901
GAGGTCAAAC GCCACAAGCT CGAAACCGGC ATCCGCCTCG ATTCGGAATA


 


951
CGGTTTGGGC GGCAAAATCG CCTACGACTA TTACAACCTC TTCAACAAAG


 


1001
GCTATATCGG TTCGGTCGTC TGGGATATGG ACAAATACGA AACCACGCTT


 


1051
GCCGCCGGCA TCAGCCAGCC GCGCAACTAT CGGGGCAACT ACTGGACAAG


 


1101
CAACGTTTCC TACAACCGTT CGACCACCCA AAACCTCGAA AAACGCGCCT


 


1151
TCTCCGGCGG CATCTGGTAT GTGCGCGACC GCGCGGGCAT CGATGCCAGG


 


1201
CTGGGGGCGG AGTTTCTCGC AGAAGGCCGG AAAATCCCCG GCTCGGATAT


 


1251
CGATTTGGGC AACAGCCACG CCACGATGCT GACCGCCTCT TGGAAACGCC


 


1301
AGCTGCTCAA CAACGTGCTG CATCCCGAAA ACGGCCATTA CCTCGACGGC


 


1351
AAAATCGGTA CGACTTTGGG CGCATTCCTG TCCTCCACCG CGCTGATCCG


 


1401
CACCTCTGCC CGCGCAGGTT ATTTCTTCAC GCCCGAAAAC AAAAAACTCG


 


1451
GCACGTTCAT CATACGCGGA CAAGCGGGTT ACACCGTTGC CCGCGACAAT


 


1501
GCCAACGTTC CTTCAGGGCT GATGTTCCGC AGCGGCGGCG CGTCTTCCGT


 


1551
GCGCGGTTAC GAACTCGACA GCATCGGGCT TGCCGGCCCG AACGGATCGG


 


1601
TCCTGCCCGA ACGCGCCCTC TTGGTGGGCA GCCTGGAATA CCAACTGCCG


 


1651
TTTACGCGCA CCCTTTCCGG CGCGGTGTTC CACGATATGG GCGACGCCGC


 


1701
CGCCAATTTC AAACGTATGA AGCTGAAACA CGGTTCGGGA CTGGGCGTGC


 


1751
GCTGGTTCAG CCCGCTCGCG CCGTTTTCCT TCGACATCGC CTACGGGCAC


 


1801
AGCGACAAGA AAATCCGCTG GCACATCAGC TTGGGAACGC GCTTCTAA






This corresponds to the amino acid sequence <SEQ ID 1198; ORF 286.a>:










a286.pep




1
MHDTRTMMIK PTALLLPALF FFPHAYAPAA DLSENKAAGF ALFKNKSPDT


 


51
ESVKLKPKFP VRIDTQDSEI KDMVEEHLPL ITQQQEEVLD KEQTGFLAEE


 


101
APDNVKTMLR SKGYFSSKVS LTEKDGAYTV HITPGPRTKI ANVGVAILGD


 


151
ILSDGNLAEY YRNALENWQQ PVGSDFDQDS WENSKTSVLG AVTRKAYPLA


 


201
KLGNTRAAVN PDTATADLNV VVDSGRPIAF GDFEITGTQR YPEQIVSGLA


 


251
RFQPGTPYDL DLLLDFQQAL EQNGHYSGAS VQADFDRLQG DRVPVKVSVT


 


301
EVKRHKLETG IRLDSEYGLG GKIAYDYYNL FNKGYIGSVV WDMDKYETTL


 


351
AAGISQPRNY RGNYWTSNVS YNRSTTQNLE KRAFSGGIWY VRDRAGIDAR


 


401
LGAEFLAEGR KIPGSDIDLG NSHATMLTAS WKRQLLNNVL HPENGHYLDG


 


451
KIGTTLGAFL SSTALIRTSA RAGYFFTPEN KKLGTFIIRG QAGYTVARDN


 


501
ANVPSGLMFR SGGASSVRGY ELDSIGLAGP NGSVLPERAL LVGSLEYQLP


 


551
FTRTLSGAVF HDMGDAAANF KRMKLKHGSG LGVRWFSPLA PFSFDIAYGH


 


601
SDKKIRWHIS LGTRF*






m286/a286 98.7% identity in 615 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1199>:










g287.seq




1
atgtttaaac gcagtgtgat tgcaatggct tgtatttttc ccctttcagc


 


51
ctgtgggggc ggcggtggcg gatcgcccga tgtcaagtcg gcggacacgc


 


101
cgtcaaaacc ggccgccccc gttgttgctg aaaatgccgg ggaaggggtg


 


151
ctgccgaaag aaaagaaaga tgaggaggca gcgggcggtg cgccgcaagc


 


201
cgatacgcag gacgcaaccg ccggagaagg cagccaagat atggcggcag


 


251
tttcggcaga aaatacaggc aatggcggtg cggcaacaac ggacaacccc


 


301
aaaaatgaag acgcgggggc gcaaaatgat atgccgcaaa atgccgccga


 


351
atccgcaaat caaacaggga acaaccaacc cgccggttct tcagattccg


 


401
cccccgcgtc aaaccctgcc cctgcgaatg gcggtagcga ttttggaagg


 


451
acgaacgtgg gcaattctgt tgtgattgac ggaccgtcgc aaaatataac


 


501
gttgacccac tgtaaaggcg attcttgtaa tggtgataat ttattggatg


 


551
aagaagcacc gtcaaaatca gaatttgaaa aattaagtga tgaagaaaaa


 


601
attaagcgat ataaaaaaga cgagcaacgg gagaattttg tcggtttggt


 


651
tgctgacagg gtaaaaaagg atggaactaa caaatatatc atcttctata


 


701
cggacaaacc acctactcgt tctgcacggt cgaggaggtc gcttccggcc


 


751
gagattccgc tgattcccgt caatcaggcc gatacgctga ttgtggatgg


 


801
ggaagcggtc agcctgacgg ggcattccgg caatatcttc gcgcccgaag


 


851
ggaattaccg gtatctgact tacggggcgg aaaaattgcc cggcggatcg


 


901
tatgccctcc gtgtgcaagg cgaaccggca aaaggcgaaa tgcttgttgg


 


951
cacggccgtg tacaacggcg aagtgctgca tttccatatg gaaaacggcc


 


1001
gtccgtaccc gtccggaggc aggtttgccg caaaagtcga tttcggcagc


 


1051
aaatctgtgg acggcattat cgacagcggc gatgatttgc atatgggtac


 


1101
gcaaaaattc aaagccgcca tcgatggaaa cggctttaag gggacttgga


 


1151
cggaaaatgg cggcggggat gtttccggaa ggttttacgg cccggccggc


 


1201
gaggaagtgg cgggaaaata cagctatcgc ccgacagatg ctgaaaaggg


 


1251
cggattcggc gtgtttgccg gcaaaaaaga tcgggattga






This corresponds to the amino acid sequence <SEQ ID 1200; ORF 287.ng>:










g287.pep




1
MFKRSVIAMA CIFPLSACGG GGGGSPDVKS ADTPSKPAAP VVAENAGEGV


 


51
LPKEKKDEEA AGGAPQADTQ DATAGEGSQD MAAVSAENTG NGGAATTDNP


 


101
KNEDAGAQND MPQNAAESAN QTGNNQPAGS SDSAPASNPA PANGGSDFGR


 


151
TNVGNSVVID GPSQNITLTH CKGDSCNGDN LLDEEAPSKS EFEKLSDEEK


 


201
IKRYKKDEQR ENFVGLVADR VKKDGTNKYI IFYTDKPPTR SARSRRSLPA


 


251
EIPLIPVNQA DTLIVDGEAV SLTGHSGNIF APEGNYRYLT YGAEKLPGGS


 


301
YALRVQGEPA KGEMLVGTAV YNGEVLHFHM ENGRPYPSGG RFAAKVDFGS


 


351
KSVDGIIDSG DDLHMGTQKF KAAIDGNGFK GTWTENGGGD VSGRFYGPAG


 


401
EEVAGKYSYR PTDAEKGGFG VFAGKKDRD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1201>:










m287.seq




1
ATGTTTAAAC GCAGCGTAAT CGCAATGGCT TGTATTTTTG CCCTTTCAGC


 


51
CTGCGGGGGC GGCGGTGGCG GATCGCCCGA TGTCAAGTCG GCGGACACGC


 


101
TGTCAAAACC TGCCGCCCCT GTTGTTTCTG AAAAAGAGAC AGAGGCAAAG


 


151
GAAGATGCGC CACAGGCAGG TTCTCAAGGA CAGGGCGCGC CATCCGCACA


 


201
AGGCAGTCAA GATATGGCGG CGGTTTCGGA AGAAAATACA GGCAATGGCG


 


251
GTGCGGTAAC AGCGGATAAT CCCAAAAATG AAGACGAGGT GGCACAAAAT


 


301
GATATGCCGC AAAATGCCGC CGGTACAGAT AGTTCGACAC CGAATCACAC


 


351
CCCGGATCCG AATATGCTTG CCGGAAATAT GGAAAATCAA GCAACGGATG


 


401
CCGGGGAATC GTCTCAGCCG GCAAACCAAC CGGATATGGC AAATGCGGCG


 


451
GACGGAATGC AGGGGGACGA TCCGTCGGCA GGCGGGCAAA ATGCCGGCAA


 


501
TACGGCTGCC CAAGGTGCAA ATCAAGCCGG AAACAATCAA GCCGCCGGTT


 


551
CTTCAGATCC CATCCCCGCG TCAAACCCTG CACCTGCGAA TGGCGGTAGC


 


601
AATTTTGGAA GGGTTGATTT GGCTAATGGC GTTTTGATTG ACGGGCCGTC


 


651
GCAAAATATA ACGTTGACCC ACTGTAAAGG CGATTCTTGT AGTGGCAATA


 


701
ATTTCTTGGA TGAAGAAGTA CAGCTAAAAT CAGAATTTGA AAAATTAAGT


 


751
GATGCAGACA AAATAAGTAA TTACAAGAAA GATGGGAAGA ATGATAAATT


 


801
TGTCGGTTTG GTTGCCGATA GTGTGCAGAT GAAGGGAATC AATCAATATA


 


851
TTATCTTTTA TAAACCTAAA CCCACTTCAT TTGCGCGATT TAGGCGTTCT


 


901
GCACGGTCGA GGCGGTCGCT TCCGGCCGAG ATGCCGCTGA TTCCCGTCAA


 


951
TCAGGCGGAT ACGCTGATTG TCGATGGGGA AGCGGTCAGC CTGACGGGGC


 


1001
ATTCCGGCAA TATCTTCGCG CCCGAAGGGA ATTACCGGTA TCTGACTTAC


 


1051
GGGGCGGAAA AATTGCCCGG CGGATCGTAT GCCCTTCGTG TTCAAGGCGA


 


1101
ACCGGCAAAA GGCGAAATGC TTGCGGGCGC GGCCGTGTAC AACGGCGAAG


 


1151
TACTGCATTT CCATACGGAA AACGGCCGTC CGTACCCGAC CAGGGGCAGG


 


1201
TTTGCCGCAA AAGTCGATTT CGGCAGCAAA TCTGTGGACG GCATTATCGA


 


1251
CAGCGGCGAT GATTTGCATA TGGGTACGCA AAAATTCAAA GCCGCCATCG


 


1301
ATGGAAACGG CTTTAAGGGG ACTTGGACGG AAAATGGCAG CGGGGATGTT


 


1351
TCCGGAAAGT TTTACGGCCC GGCCGGCGAG GAAGTGGCGG GAAAATACAG


 


1401
CTATCGCCCG ACAGATGCGG AAAAGGGCGG ATTCGGCGTG TTTGCCGGCA


 


1451
AAAAAGAGCA GGATTGA






This corresponds to the amino acid sequence <SEQ ID 1202; ORF 287>:










m287.pep




1
MFKRSVIAMA CIFALSACGG GGGGSPDVKS ADTLSKPAAP VVSEKETEAK


 


51
EDAPQAGSQG QGAPSAQGSQ DMAAVSEENT GNGGAVTADN PKNEDEVAQN


 


101
DMPQNAAGTD SSTPNHTPDP NMLAGNMENQ ATDAGESSQP ANQPDMANAA


 


151
DGMQGDDPSA GGQNAGNTAA QGANQAGNNQ AAGSSDPIPA SNPAPANGGS


 


201
NFGRVDLANG VLIDGPSQNI TLTHCKGDSC SGNNFLDEEV QLKSEFEKLS


 


251
DADKISNYKK DGKNDKFVGL VADSVQMKGI NQYIIFYKPK PTSFARFRRS


 


301
ARSRRSLPAE MPLIPVNQAD TLIVDGEAVS LTGHSGNIFA PEGNYRYLTY


 


351
GAEKLPGGSY ALRVQGEPAK GEMLAGAAVY NGEVLHFHTE NGRPYPTRGR


 


401
FAAKVDFGSK SVDGIIDSGD DLHMGTQKFK AAIDGNGFKG TWTENGSGDV


 


451
SGKFYGPAGE EVAGKYSYRP TDAEKGGFGV FAGKKEQD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m287/g287 70.1% identity in 499 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1203>:










a287.seq




1
ATGTTTAAAC GCAGTGTGAT TGCAATGGCT TGTATTGTTG CCCTTTCAGC


 


51
CTGTGGGGGC GGCGGTGGCG GATCGCCCGA TGTTAAGTCG GCGGACACGC


 


101
TGTCAAAACC TGCCGCCCCT GTTGTTACTG AAGATGTCGG GGAAGAGGTG


 


151
CTGCCGAAAG AAAAGAAAGA TGAGGAGGCG GTGAGTGGTG CGCCGCAAGC


 


201
CGATACGCAG GACGCAACCG CCGGAAAAGG CGGTCAAGAT ATGGCGGCAG


 


251
TTTCGGCAGA AAATACAGGC AATGGCGGTG CGGCAACAAC GGATAATCCC


 


301
GAAAATAAAG ACGAGGGACC GCAAAATGAT ATGCCGCAAA ATGCCGCCGA


 


351
TACAGATAGT TCGACACCGA ATCACACCCC TGCACCGAAT ATGCCAACCA


 


401
GAGATATGGG AAACCAAGCA CCGGATGCCG GGGAATCGGC ACAACCGGCA


 


451
AACCAACCGG ATATGGCAAA TGCGGCGGAC GGAATGCAGG GGGACGATCC


 


501
GTCGGCAGGG GAAAATGCCG GCAATACGGC AGATCAAGCT GCAAATCAAG


 


551
CTGAAAACAA TCAAGTCGGC GGCTCTCAAA ATCCTGCCTC TTCAACCAAT


 


601
CCTAACGCCA CGAATGGCGG CAGCGATTTT GGAAGGATAA ATGTAGCTAA


 


651
TGGCATCAAG CTTGACAGCG GTTCGGAAAA TGTAACGTTG ACACATTGTA


 


701
AAGACAAAGT ATGCGATAGA GATTTCTTAG ATGAAGAAGC ACCACCAAAA


 


751
TCAGAATTTG AAAAATTAAG TGATGAAGAA AAAATTAATA AATATAAAAA


 


801
AGACGAGCAA CGAGAGAATT TTGTCGGTTT GGTTGCTGAC AGGGTAGAAA


 


851
AGAATGGAAC TAACAAATAT GTCATCATTT ATAAAGACAA GTCCGCTTCA


 


901
TCTTCATCTG CGCGATTCAG GCGTTCTGCA CGGTCGAGGC GGTCGCTTCC


 


951
GGCCGAGATG CCGCTGATTC CCGTCAATCA GGCGGATACG CTGATTGTCG


 


1001
ATGGGGAAGC GGTCAGCCTG ACGGGGCATT CCGGCAATAT CTTCGCGCCC


 


1051
GAAGGGAATT ACCGGTATCT GACTTACGGG GCGGAAAAAT TGTCCGGCGG


 


1101
ATCGTATGCC CTCAGTGTGC AAGGCGAACC GGCAAAAGGC GAAATGCTTG


 


1151
CGGGCACGGC CGTGTACAAC GGCGAAGTGC TGCATTTCCA TATGGAAAAC


 


1201
GGCCGTCCGT CCCCGTCCGG AGGCAGGTTT GCCGCAAAAG TCGATTTCGG


 


1251
CAGCAAATCT GTGGACGGCA TTATCGACAG CGGCGATGAT TTGCATATGG


 


1301
GTACGCAAAA ATTCAAAGCC GTTATCGATG GAAACGGCTT TAAGGGGACT


 


1351
TGGACGGAAA ATGGCGGCGG GGATGTTTCC GGAAGGTTTT ACGGCCCGGC


 


1401
CGGCGAAGAA GTGGCGGGAA AATACAGCTA TCGCCCGACA GATGCGGAAA


 


1451
AGGGCGGATT CGGCGTGTTT GCCGGCAAAA AAGAGCAGGA TTGA






This corresponds to the amino acid sequence <SEQ ID 1204; ORF 287.a>:










a287.pep




1
MFKRSVIAMA CIVALSACGG GGGGSPDVKS ADTLSKPAAP VVTEDVGEEV


 


51
LPKEKKDEEA VSGAPQADTQ DATAGKGGQD MAAVSAENTG NGGAATTDNP


 


101
ENKDEGPQND MPQNAADTDS STPNHTPAPN MPTRDMGNQA PDAGESAQPA


 


151
NQPDMANAAD GMQGDDPSAG ENAGNTADQA ANQAENNQVG GSQNPASSTN


 


201
PNATNGGSDF GRINVANGIK LDSGSENVTL THCKDKVCDR DFLDEEAPPK


 


251
SEFEKLSDEE KINKYKKDEQ RENFVGLVAD RVEKNGTNKY VIIYKDKSAS


 


301
SSSARFRRSA RSRRSLPAEM PLIPVNQADT LIVDGEAVSL TGHSGNIFAP


 


351
EGNYRYLTYG AEKLSGGSYA LSVQGEPAKG EMLAGTAVYN GEVLHFHMEN


 


401
GRPSPSGGRF AAKVDFGSKS VDGIIDSGDD LHMGTQKFKA VIDGNGFKGT


 


451
WTENGGGDVS GRFYGPAGEE VAGKYSYRPT DAEKGGFGVF AGKKEQD*






m287/a287 77.2% identity in 501 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1205>:










g288.seq




1
atgcacaccg gacaggcggt aagccgggtt ctgtctcgga cagtcattcc


 


51
tctaggcata ccgttgccgg tatgctcaag caacctaccc gaacgctcgg


 


101
cgggcagcgt cattgcgttc tgtttggtct tgctccgaat ggggtttggc


 


151
ctgccgcata ttgttaccaa atgcgcggtg cgcccttacc gcaccttttc


 


201
acccttgcct gtgctgccaa agcagccatc ggcggttttg ctttctgttc


 


251
cactttccgt cgcgttaccg cgcccggccg ttaaccggca ttctaccctg


 


301
cggagcccgg actttcctcc ccgtatgcct tacgcgatac gcggcgactg


 


351
tctgcccgtc ccgtgtgcgg cgcggattat aacacgaaac gcaaaaatgc


 


401
cgtctgaaac ggtacaggtt tcagacggca tacagcctaa actacacacc


 


451
ctgtttcagg ctggcttcga tgaagccgtc caagtcgccg tccaatacgg


 


501
ctttgtggtt gccgacttcg tagcctgtac gcaagtcttt gatgcgtga






This corresponds to the amino acid sequence <SEQ ID 1206; ORF 288.ng>:










g288.pep




1
MHTGQAVSRV LSRTVIPLGI PLPVCSSNLP ERSAGSVIAF CLVLLRMGFG


 


51
LPHIVTKCAV RPYRTFSPLP VLPKQPSAVL LSVPLSVALP RPAVNRHSTL


 


101
RSPDFPPRMP YAIRGDCLPV PCAARIITRN AKMPSETVQV SDGIQPKLHT


 


151
LFQAGFDEAV QVAVQYGFVV ADFVACTQVF DA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1207>:










m288.seq




1
ATGCACACCG GACAGGCGGT AAGCCGGGTT CTGTCTCGGA CAGTCATTCC


 


51
TCTAGGCATA CCGTTACCGG TATGCTCAAG CAACCTACCC GAACGCTCGG


 


101
CGGGCAGCGT CATTGCGTTC TGTTTGGTCT TGCTCCGAAT GGGGTTTGGC


 


151
CTGCCGCATA TTGTTACCAA ATGCGCGGTG CGCCCTTACC GCACCTTTTC


 


201
ACCCTTACCT GTGCTGCCAA AGCAGCCATC GGCGGTTTTG CTTTCTGTTC


 


251
CACTTTCCGT CGCGTTACCG CGCCCGGCCG TTAACCGGCA TTCTACCCTG


 


301
CGGAGCCCGG ACTTTCCTCC CCGTATGCCT TACGCGATAC GCGGCGACTG


 


351
TCTGCCCGTC CCGTGTGCGG CGCGGATTAT AACACGAAAC ACAAAAATGC


 


401
CGTCTGAAAC GGTACAGGTT TCAGACGGCA TACAGCCTAA ACTACACGCC


 


451
CTGTTTCAGG CTGGCTTCGA TGAAGCCGTC CAAGTCGCCA TCCAATACGG


 


501
CTTTGGTGTT GCCGACTTCG TAGCCTGTAC GCAAGTCTTT GATACGTGA






This corresponds to the amino acid sequence <SEQ ID 1208; ORF 288>:










m288.pep




1
MHTGQAVSRV LSRTVIPLGI PLPVCSSNLP ERSAGSVIAF CLVLLRMGFG


 


51
LPHIVTKCAV RPYRTFSPLP VLPKQPSAVL LSVPLSVALP RPAVNRHSTL


 


101
RSPDFPPRMP YAIRGDCLPV PCAARIITRN TKMPSETVQV SDGIQPKLHA


 


151
LFQAGFDEAV QVAIQYGFGV ADFVACTQVF DT*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m288/g288 97.8% identity in 181 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1209>:










a288.seq




1
ATGCACACCG GACAGGCGGT AAGCCGGGTT CTGTCTCGGA CAGTCATTCC


 


51
TCTAGGCATA CCGTTGCCGG TATGCTCAAG CAACCTACCC GAACGCTCGG


 


101
CGGGCAGCGT CATTGCGTTC TGTTTGGTCT TGCTCCGAAT GGGGTTTGGC


 


151
CTGCCGCATA TTGTTACCAA ATGCGCGGTG CGCCCTTACC GCACCTTTTC


 


201
ACCCTTGCCT GTGCTGCCAA AGCAGCCATC GGCGGTTTTG CTTTCTGTTC


 


251
CACTTTCCGT CGCGTTACCG CGCCCGGCCG TTAACCGGCA TTCTACCCTG


 


301
CGGAGCCCGG ACTTTCCTCC CCGTATGCCT TACGCGATAC GCGGCGACTG


 


351
TCTGCCCGTC CCGTGTGCGG CGCGGATTAT AACACGAAAC GCAAAAATGC


 


401
CGTCTGAAAC GGTACAGGTT TCAGACGGCA TACAGCCTAA ACTACACGCC


 


451
CTGTTTCAGG CTGGCTTCGA TAAAGCCGTC CAAGTCGCCG TCCAATACGG


 


501
CTTTGGTGTT GCCGACTTCG TAGCCTGTGC GCAAGTCTTT AATGCGTGA






This corresponds to the amino acid sequence <SEQ ID 1210; ORF 288.a>:










a288.pep




1
MHTGQAVSRV LSRTVIPLGI PLPVCSSNLP ERSAGSVIAF CLVLLRMGFG


 


51
LPHIVTKCAV RPYRTFSPLP VLPKQPSAVL LSVPLSVALP RPAVNRHSTL


 


101
RSPDFPPRMP YAIRGDCLPV PCAARIITRN AKMPSETVQV SDGIQPKLHA


 


151
LFQAGFDKAV QVAVQYGFGV ADFVACAQVF NA*






m288/a288 97.2% identity in 181 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1211>:










g290.seq




1
atggcaaaaa tgatgaaatg ggcggctgtt gcggcggtcg cggcggcagc


 


51
ggtttggggc ggatggtctt atctgaagcc cgaaccgcag gctgcttata


 


101
ttacggaagc ggtcaggcgc ggcgatatca gccggacggt ttccgcgacg


 


151
ggcgagattt cgccgtccaa cctggtatcg gtcggcgcgc aggcttcggg


 


201
gcagattaaa aagctttatg tcaaactcgg gcaacaggtc aaaaagggcg


 


251
atttgattgc ggaaatcaat tcgaccacgc agaccaacac gatcgatatg


 


301
gaaaaatcca aattggaaac gtatcaggcg aagctggtgt ccgcacagat


 


351
tgcattgggc agcgcggaaa aaaaatataa gcgtcaggcg gcgttgtgga


 


401
aggatgatgc gacctctaaa gaagatttgg aaagcgcgca ggatgcgctt


 


451
gccgccgcca aagccaatgt tgccgagttg aaggctttaa tcagacagag


 


501
caaaatttcc atcaataccg ccgagtcgga tttgggctac acgcgcatta


 


551
ccgcgacgat ggacggcacg gtggtggcga ttcccgtgga agaggggcag


 


601
actgtgaacg cggcgcagtc tacgccgacg attgtccaat tggcgaatct


 


651
ggatatgatg ttgaacaaaa tgcagattgc cgagggcgat attaccaagg


 


701
tgaaggcggg gcaggatatt tcgtttacga ttttgtccga accggatacg


 


751
ccgattaagg cgaagctcga cagcgtcgac cccgggctga ccacgatgtc


 


801
gtcgggcggc tacaacagca gtacggatac ggcttccaat gcggtctatt


 


851
attatgcccg ttcgtttgtg ccgaatccgg acggcaaact cgccacgggg


 


901
atgacgacgc agaatacggt tgaaatcgac ggtgtgaaaa atgtgttgct


 


951
tattccgtcg ctgaccgtga aaaatcgcgg cggcaaggcg ttcgtacgcg


 


1001
tgttgggtgc ggacggcaag gcagtggaac gcgaaatccg gaccggtatg


 


1051
aaagacagta tgaataccga agtgaaaagc gggttgaaag agggggacaa


 


1101
agtggtcatc tccgaaataa ccgccgccga gcagcaggaa agcggcgaac


 


1151
gcgccctagg cggcccgccg cgccgataa






This corresponds to the amino acid sequence <SEQ ID 1212; ORF 290.ng>:










g290.pep




1
MAKMMKWAAV AAVAAAAVWG GWSYLKPEPQ AAYITEAVRR GDISRTVSAT


 


51
GEISPSNLVS VGAQASGQIK KLYVKLGQQV KKGDLIAEIN STTQTNTIDM


 


101
EKSKLETYQA KLVSAQIALG SAEKKYKRQA ALWKDDATSK EDLESAQDAL


 


151
AAAKANVAEL KALIRQSKIS INTAESDLGY TRITATMDGT VVAIPVEEGQ


 


201
TVNAAQSTPT IVQLANLDMM LNKMQIAEGD ITKVKAGQDI SFTILSEPDT


 


251
PIKAKLDSVD PGLTTMSSGG YNSSTDTASN AVYYYARSFV PNPDGKLATG


 


301
MTTQNTVEID GVKNVLLIPS LTVKNRGGKA FVRVLGADGK AVEREIRTGM


 


351
KDSMNTEVKS GLKEGDKVVI SEITAAEQQE SGERALGGPP RR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1213>:









m290.seq (partial)










1
..GTATCGGTCG GCGCGCAGGC ATCGGGGCAG ATTAAGATAC TTTATGTCAA



 


51
  ACTCGGGCAA CAGGTTAAAA AGGGCGATTT GATTGCGGAA ATCAATTCGA


 


101
  CCTCGCAGAC CAATACGCTC AATACGGAAA AATCCAAGTT GGAAACGTAT


 


151
  CAGGCGAAGC TGGTGTCGGC ACAGATTGCA TTGGGCAGCG CGGAGAAGAA


 


201
  ATATAAGCGT CAGGCGGCGT TATGGAAGGA AAACGCGACT TCCAAAGAGG


 


251
  ATTTGGAAAG CGCGCAGGAT GCGTTTGCCG CCGCCAAAGC CAATGTTGCC


 


301
  GAGCTGAAGG CTTTAATCAG ACAGAGCAAA ATTTCCATCA ATACCGCCGA


 


351
  GTCGGAATTG GGCTACACGC GCATTACCGC AACGATGGAC GGCACGGTGG


 


401
  TGGCGATTCT CGTGGAAGAG GGGCAGACTG TGAACGCGGC GCAGTCTACG


 


451
  CCGACGATTG TCCAATTGGC GAATCTGGAT ATGATGTTGA ACAAAATGCA


 


501
  GATTGCCGAG GGCGATATTA CCAAGGTGAA GGCGGGGCAG GATATTTCGT


 


551
  TTACGATTTT GTCCGAACCG GATACGCCGA TTAAGGCGAA GCTCGACAGC


 


601
  GTCGACCCCG GGCTGACCAC GATGTCGTCG GGCGGTTACA ACAGCAGTAC


 


651
  GGATACGGCT TCCAATGCGG TCTACTATTA TGCCCGTTCG TTTGTGCCGA


 


701
  ATCCGGACGG CAAACTCGCC ACGGGGATGA CGACGCAGAA TACGGTTGAA


 


751
  ATCGACGGCG TGAAAAATGT GCTGATTATT CCGTCGCTGA CCGTGAAAAA


 


801
  TCGCGGCGGC AAGGCGTTTG TGCGCGTGTT GGGTGCGGAC GGCAAGGCGG


 


851
  CGGAACGCGA AATCCGGACC GGTATGAGAG ACAGTATGAA TACCGAAGTA


 


901
  AAAAGCGGGT TGAAAGAGGG GGACAAAGTG GTCATCTCCG AAATAACCGC


 


951
  CGCCGAGCAA CAGGAAAGCG GCGAACGCGC CCTAGGCGGC CCGCCGCGCC


 


1001
  GATAA






This corresponds to the amino acid sequence <SEQ ID 1214; ORF 290>:









m290.pep (partial)










1
..VSVGAQASGQ IKILYVKLGQ QVKKGDLIAE INSTSQTNTL NTEKSKLETY



 


51
  QAKLVSAQIA LGSAEKKYKR QAALWKENAT SKEDLESAQD AFAAAKANVA


 


101
  ELKALIRQSK ISINTAESEL GYTRITATMD GTVVAILVEE GQTVNAAQST


 


151
  PTIVQLANLD MMLNKMQIAE GDITKVKAGQ DISFTILSEP DTPIKAKLDS


 


201
  VDPGLTTMSS GGYNSSTDTA SNAVYYYARS FVPNPDGKLA TGMTTQNTVE


 


251
  IDGVKNVLII PSLTVKNRGG KAFVRVLGAD GKAAEREIRT GMRDSMNTEV


 


301
  KSGLKEGDKV VISEITAAEQ QESGERALGG PPRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m290/g290 96.1% identity in 334 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1215>:










a290.seq




1
ATGGCAAAAA TGATGAAATG GGCGGCTGTT GCGGCGGTCG CGGCGGCAGC


 


51
GGTTTGGGGC GGATGGTCTT ATCTGAAGCC CGAGCCGCAG GCTGCTTATA


 


101
TTACGGAAAC GGTCAGGCGC GGCGACATCA GCCGGACGGT TTCTGCAACA


 


151
GGGGAGATTT CGCCGTCCAA CCTGGTATCG GTCGGCGCGC AGGCATCGGG


 


201
GCAGATTAAG AAACTTTATG TCAAACTCGG GCAACAGGTT AAAAAGGGCG


 


251
ATTTGATTGC GGAAATCAAT TCGACCTCGC AGACCAATAC GCTCAATACG


 


301
GAAAAATCCA AATTGGAAAC GTATCAGGCG AAGCTGGTGT CGGCACAGAT


 


351
TGCATTGGGC AGCGCGGAGA AGAAATATAA GCGTCAGGCG GCGTTGTGGA


 


401
AGGATGATGC GACCGCTAAA GAAGATTTGG AAAGCGCACA GGATGCGCTT


 


451
GCCGCCGCCA AAGCCAATGT TGCCGAGCTG AAGGCTCTAA TCAGACAGAG


 


501
CAAAATTTCC ATCAATACCG CCGAGTCGGA ATTGGGCTAC ACGCGCATTA


 


551
CCGCAACGAT GGACGGCACG GTGGTGGCGA TTCTCGTGGA AGAGGGGCAG


 


601
ACTGTGAACG CGGCGCAGTC TACGCCGACG ATTGTCCAAT TGGCGAATCT


 


651
GGATATGATG TTGAACAAAA TGCAGATTGC CGAGGGCGAT ATTACCAAGG


 


701
TGAAGGCGGG GCAGGATATT TCGTTTACGA TTTTGTCCGA ACCGGATACG


 


751
CCGATTAAGG CGAAGCTCGA CAGCGTCGAC CCCGGGCTGA CCACGATGTC


 


801
GTCGGGCGGC TACAACAGCA GTACGGATAC GGCTTCCAAT GCGGTCTACT


 


851
ATTATGCCCG TTCGTTTGTG CCGAATCCGG ACGGCAAACT CGCCACGGGG


 


901
ATGACGACGC AGAATACGGT TGAAATCGAC GGTGTGAAAA ATGTGCTGAT


 


951
TATTCCGTCG CTGACCGTGA AAAATCGCGG CGGCAGGGCG TTTGTGCGCG


 


1001
TGTTGGGTGC AGACGGCAAG GCGGCGGAAC GCGAAATCCG GACCGGTATG


 


1051
AGAGACAGTA TGAATACCGA AGTAAAAAGC GGGTTGAAAG AGGGGGACAA


 


1101
AGTGGTCATC TCCGAAATAA CCGCCGCCGA GCAGCAGGAA AGCGGCGAAC


 


1151
GCGCCCTAGG CGGCCCGCCG CGCCGATAA






This corresponds to the amino acid sequence <SEQ ID 1216; ORF 290.a>:










a290.pep




1
MAKMMKWAAV AAVAAAAVWG GWSYLKPEPQ AAYITETVRR GDISRTVSAT


 


51
GEISPSNLVS VGAQASGQIK KLYVKLGQQV KKGDLIAEIN STSQTNTLNT


 


101
EKSKLETYQA KLVSAQIALG SAEKKYKRQA ALWKDDATAK EDLESAQDAL


 


151
AAAKANVAEL KALIRQSKIS INTAESELGY TRITATMDGT VVAILVEEGQ


 


201
TVNAAQSTPT IVQLANLDMM LNKMQIAEGD ITKVKAGQDI SFTILSEPDT


 


251
PIKAKLDSVD PGLTTMSSGG YNSSTDTASN AVYYYARSFV PNPDGKLATG


 


301
MTTQNTVEID GVKNVLIIPS LTVKNRGGRA FVRVLGADGK AAEREIRTGM


 


351
RDSMNTEVKS GLKEGDKVVI SEITAAEQQE SGERALGGPP RR*






m290/a290 98.2% identity in 334 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1217>:










g292.seq




1
atgaaaacca agttaatcaa aatcttgacc ccctttaccg tcctgccgct


 


51
gctggcttgc gggcaaacgc ccgtttccaa tgccaacgcc gaatccgccg


 


101
tcaaagccga atccgccggc aaatccgttg ccgcttcttt gaaagcgcgt


 


151
ttggaaaaaa cctattccgc ccaagatttg aaagtgttga gcgtcagcga


 


201
aacaccggtc aaaggcattt acgaagtcgt cgtcagcggc aggcagatta


 


251
tctacaccga tgccgaaggc ggctatatgt tcgtcggcga actcatcaac


 


301
atcgacacgc gcaaaaacct gaccgaagaa cgcgccgccg atttgaacaa


 


351
aatcgacttc gcctccctgc ctttggacaa agccatcaaa gaagtacgcg


 


401
gcaacggcaa gctgaaagtc gccgtcttct ccgaccccga ttgtccgttc


 


451
tgcaaacgct tggaacatga gtttgaaaaa atgaccgacg tgacggttta


 


501
cagctttatg atgcccattg ccggcctgca cccagatgcc gcgcgcaagg


 


551
cgcaaatctt atggtgtcag cccgaccgtg ccaaagcgtg gacggattgg


 


601
atgcgtaaag gcaaattccc ggtcggcggc agcatctgcg acaatcccgt


 


651
cgcggaaacc acttccttgg gcgaacagtt cggcttcaac ggcacgccga


 


701
cccttcgtct tccccaacgg gcgcacccaa agcggttaca gcccgatgcc


 


751
ccaactggag gaaatcatcc gcaaaaacca gcagtaaacc cgcaatga






This corresponds to the amino acid sequence <SEQ ID 1218; ORF 292.ng>:










g292.pep




1
MKTKLIKILT PFTVLPLLAC GQTPVSNANA ESAVKAESAG KSVAASLKAR


 


51
LEKTYSAQDL KVLSVSETPV KGIYEVVVSG RQIIYTDAEG GYMFVGELIN


 


101
IDTRKNLTEE RAADLNKIDF ASLPLDKAIK EVRGNGKLKV AVFSDPDCPF


 


151
CKRLEHEFEK MTDVTVYSFM MPIAGLHPDA ARKAQILWCQ PDRAKAWTDW


 


201
MRKGKFPVGG SICDNPVAET TSLGEQFGFN GTPTLRLPQR AHPKRLQPDA


 


251
PTGGNHPQKP AVNPQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1219>:










m292.seq




1
ATGAAAACCA AGTTAATCAA AATCTTGACC CCCTTTACCG TCCTCCCGCT


 


51
GCTGGCTTGC GGGCAAACGC CCGTTTCCAA TGCCAACGCC GAACCCGCCG


 


101
TCAAAGCCGA GTCCGCCGGC AAATCCGTTG CCGCCTCTTT GAAAGCGCGT


 


151
TTGGAAAAAA CCTATTCCGC CCAAGATTTG AAAGTGTTGA GCGTCAGCGA


 


201
AACACCGGTC AAAGGCATTT ACGAAGTCGT CGTCAGCGGC AGGCAGATTA


 


251
TCTACACCGA TGCCGAAGGC GGCTATATGT TCGTCGGCGA ACTCATCAAC


 


301
ATCGACACGC GCAAAAACCT GACCGAAGAA CGCGCCGCCG ATTTGAACAA


 


351
AATCGACTTC GCCTCCCTGC CTTTGGACAA AGCCATCAAA GAAGTGCGCG


 


401
GCAACGGCAA GCTGAAAGTC GCCGTCTTCT CCGACCCCGA TTGTCCGTTC


 


451
TGCAAACGCT TGGAACACGA GTTTGAAAAA ATGACCGACG TGACGGTTTA


 


501
CAGCTTTATG ATGCCCATTG CCGGCCTGCA CCCCGATGCC GCGCGCAAGG


 


551
CGCAAATCTT ATGGTGTCAG CCCGACCGCG CCAAAGCGTG GACGGATTGG


 


601
ATGCGTAAAG GCAAATTCCC GGTCGGCGGC AGCATCTGCG ACAATCCCGT


 


651
CGCGGAAACC ACTTCCTTGG GCGAACAATT CGGCTTCAAC GGCACGCCGA


 


701
CCCTCGTCTT CCCCAACGGG CGCAGCCAAA GCGGCTACAG CCCGATGCCC


 


751
CAACTGGAGG AAATCATCCG CAAAAATCAA TAA






This corresponds to the amino acid sequence <SEQ ID 1220; ORF 292>:










m292.pep




1
MKTKLIKILT PFTVLPLLAC GQTPVSNANA EPAVKAESAG KSVAASLKAR


 


51
LEKTYSAQDL KVLSVSETPV KGIYEVVVSG RQIIYTDAEG GYMFVGELIN


 


101
IDTRKNLTEE RAADLNKIDF ASLPLDKAIK EVRGNGKLKV AVFSDPDCPF


 


151
CKRLEHEFEK MTDVTVYSFM MPIAGLHPDA ARKAQILWCQ PDRAKAWTDW


 


201
MRKGKFPVGG SICDNPVAET TSLGEQFGFN GTPTLVFPNG RSQSGYSPMP


 


251
QLEEIIRKNQ *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m292/g292 98.7% identity in 238 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1221>:










a292.seq




1
ATGAAAACCA AGTTAATCAA AATCTTGACC CCCTTTACCG TCCTCCCGCT


 


51
GCTGGCTTGC GGGCAAACGC CCGTTTCCAA TGCCAACGCC GAACCCGCCG


 


101
TCAAAGCCGA GTCCGCCGGC AAATCCGTTG CCGCCTCTTT GAAAGCGCGT


 


151
TTGGAAAAAA CCTATTCCGC CCAAGATTTG AAAGTGTTGA GCGTCAGCGA


 


201
AACACCGGTC AAAGGCATTT ACGAAGTCGT CGTCAGCGGC AGGCAGATTA


 


251
TCTACACCGA TGCCGAAGGC GGCTATATGT TCGTCGGCGA ACTCATCAAC


 


301
ATCGACACGC GCAAAAACCT GACCGAAGAA CGCGCCGCCG ATTTGAACAA


 


351
AATCGACTTC GCCTCCCTGC CTTTGGACAA AGCCATCAAA GAAGTGCGCG


 


401
GCAACGGCAA GCTGAAAGTC GCCGTCTTCT CCGACCCCGA TTGTCCGTTC


 


451
TGCAAACGCT TGGAACACGA GTTTGAAAAA ATGACCGACG TGACGGTTTA


 


501
CAGCTTTATG ATGCCCATTG CCGGCCTGCA CCCCGATGCC GCGCGCAAGG


 


551
CGCAAATCTT ATGGTGTCAG CCCGACCGCG CCAAAGCGTG GACGGATTGG


 


601
ATGCGTAAAG GCAAATTCCC GGTCGGCGGC AGCATCTGCG ACAATCCCGT


 


651
CGCGGAAACC ACTTCCTTGG GCGAACAATT CGGCTTCAAC GGCACGCCGA


 


701
CCCTCGTCTT CCCCAACGGG CGCAGCCAAA GCGGCTACAG CCCGATGCCC


 


751
CAACTGGAGG AAATCATCCG CAAAAATCAA TAA






This corresponds to the amino acid sequence <SEQ ID 1222; ORF 292.a>:










a292.pep




1
MKTKLIKILT PFTVLPLLAC GQTPVSNANA EPAVKAESAG KSVAASLKAR


 


51
LEKTYSAQDL KVLSVSETPV KGIYEVVVSG RQIIYTDAEG GYMFVGELIN


 


101
IDTRKNLTEE RAADLNKIDF ASLPLDKAIK EVRGNGKLKV AVFSDPDCPF


 


151
CKRLEHEFEK MTDVTVYSFM MPIAGLHPDA ARKAQILWCQ PDRAKAWTDW


 


201
MRKGKFPVGG SICDNPVAET TSLGEQFGFN GTPTLVFPNG RSQSGYSPMP


 


251
QLEEIIRKNQ *






m292/a292 100.0% identity in 260 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1223>:









g294.seq (partial)










1
atgcgtatta cctgtgcgcc gatgtcgctt ttgtcggcgg cagtctggtc



 


51
ggttcgggct gtcagaacat catcgaaccg ctttcctgcg gcgttacgac


 


101
gatattcggc ttttcgacct acaatttttc cgaagcctgc cggcacgcct


 


151
tggcatcggg tgcggcggtt caagtcgaat cggcggacgc gtggcgtgaa


 


201
gccgttgaaa aaaccttatc tggcgagggg ggcggaatgc agatgcaggc


 


251
gcgcgtggac ggctttatcg cacaacatcg cggagcgggc gcgagaatcg


 


301
ccgaggcggt gcgggaagcg gtatgcggac atcgggggcg atagtgatac


 


351
aatccgtatc cgagttttcc ggttggagca tcgtatgagt atttatgccg


 


401
tcgcgcacat catccacctg tattgcgcca ccgcctttgt cggcggcgtg


 


451
ttttttgaag tgctggtttt gtccgtcctg catacgggac gggtgtcgcg


 


501
cgaggcgcgg cgcgaagtgg aaaaggcaat gtcttaccgc gccgtcaggg


 


551
tgatgccgtt tgcggtcgga ctgctgttcg ccaggggaac tctagagtcg


 


601
actgcagcag catgccctc.. .






This corresponds to the amino acid sequence <SEQ ID 1224; ORF 294.ng>:









g294.pep (partial)










1
MRITCAPMSL LSAAVWSVRA VRTSSNRFPA ALRRYSAFRP TIFPKPAGTP



 


51
WHRVRRFKSN RRTRGVKPLK KPYLARGAEC RCRRAWTALS HNIAERARES


 


101
PRRCGKRYAD IGGDSDTIRI RVFRLEHRMS IYAVAHIIHL YCATAFVGGV


 


151
FFEVLVLSVL HTGRVSREAR REVEKAMSYR AVRVMPFAVG LLFARGTLES


 


201
TAAACP....






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1225>:










m294.seq




1
ATGCGTATTA CCTGTGCGCC GATGTCGCTT TTGTCGGCGG CAGTCTGGTC


 


51
GATTCGGGTT GTCAGAACAT CATCGAACCG CTTTCCTGCG GCGTTCCGAC


 


101
GATATTCGGC TTTTCAACCT ACAATTTTTC CGAAGCCTGC CGACACGCCT


 


151
TGGCATCGGG TGCGGCGGTT CAAGTCGAAT CGGCGGATGC GTGGCGGGAA


 


201
GCCGTTGAAA AAACCTTATC GTCCGAGGGG GGGGGGATGC AGATGCAGGC


 


251
GCGCGTGGAC GGCTTTATCG CACAACATCG CGGAGCGGGC GCGAGAATCG


 


301
CCGAGGCGGT GCGGGAAGCG GTATGCGGAT ATCGGGGGCG ATAGTGATAC


 


351
AATCCGTATC CGAGTTTTCC GTTTGGAGCA TCGTATGAGT ATTTATGCCG


 


401
TCGCGCACAT CGTTCATCTG TATTGCGCTA TTGCCTTTGT CGGCGGCGTG


 


451
TTTTTTGAAG TGCTGGTTTT GTCCGTCCTG CATACGGGAC GGGTGTCGCG


 


501
CGAGGCGCGG CGCGAAGTGG AAAAGGCAAT GTCTTACCGC GCCGTCAGGG


 


551
TGATGCCGTT TGTGGTCGGA CTGCTGTTCG CCAGCGGCAT CGTGATGGCG


 


601
GCAAACCGCT ATCTTTCTAT ATTGGGCGAA CCGTTTGCCA CTTCCTTCGG


 


651
TACGATGCTG ACGCTGAAAA TCCTGTTGGC GTTCAGCGTA TTGGCGCACT


 


701
TCGCCATCGC CGTCGTCAAA ATGGCGCGTT CCACACTGAC GGTCGGTTGG


 


751
TCGAAATACA TACACGCCGT CGTCTTTACC CATATGcTGC TGATTGTCTT


 


801
TTTGGCAAAA GCGATGTTTT ATATCAGCTG GTAA






This corresponds to the amino acid sequence <SEQ ID 1226; ORF 294>:










m294.pep




1
MRITCAPMSL LSAAVWSIRV VRTSSNRFPA AFRRYSAFQP TIFPKPADTP


 


51
WHRVRRFKSN RRMRGGKPLK KPYRPRGGGC RCRRAWTALS HNIAERARES


 


101
PRRCGKRYAD IGGDSDTIRI RVFRLEHRMS IYAVAHIVHL YCAIAFVGGV


 


151
FFEVLVLSVL HTGRVSREAR REVEKAMSYR AVRVMPFVVG LLFASGIVMA


 


201
ANRYLSILGE PFATSFGTML TLKILLAFSV LAHFAIAVVK MARSTLTVGW


 


251
SKYIHAVVFT HMLLIVFLAK AMFYISW*






g294/m294 92.3% identity in 196 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1227>:










a294.seq




1
ATGCGTATTA CCTGTGCGCC GATGTCGCTT TTGTCGGCGG CAGTCTGGTC


 


51
GATTCGGGCT GTCAGAACAT CATCGAACCG CTTTCCTGCG GCGTTCCGAC


 


101
GATATTCGGC TTTTCGACCT ACAATTTTTC CGAAGCCTGC CGGCACGCCT


 


151
TGGCATCGGG TGCGGCGGTT CAAGTCGAAT CGGCGGACGC GTGGCGGGAA


 


201
GCCGTTGAAA AAAACTTATC GTCCGAGGAG GGCGGAATGC AGATGCAGGC


 


251
GCGCGCGGAC GGCTTTATCG CACAACATCG CGGAGCGGGC GCGAGAATCG


 


301
CCGAGGCGGT ACGGGAAGCG GTATGCGGAC ATCGGGGACG ATAGTGATAC


 


351
AATCCGTATC CGAGTTTTCC GGTTGGAGTA CCGTATGAGT ATTTATGCCG


 


401
TCGCGCACAT CGTCCACCTG TATTGCGCCA TCGCCTTTGT CGGCGGCGTG


 


451
TTTTTTGAAG TGCTGGTTTT GTCCGTCCTG CATACGGGAC GGGTGTCGTG


 


501
CGAGGCGCGG CGCGAAGTGG AAAAGGCAAT GTCTTACCGC GCCGTCAGGG


 


551
TGATGCCGTT TGTGGTCGGA CTGCTGTTCG CCAGCGGCAT CGTGATGGCG


 


601
GCAAACCGCT ATCTTTCTAT ATTGGGCGAA CCGTTTGCCA CTTCCTTCGG


 


651
TACGATGCTG ACGCTGAAAA TCCTGTTGGC GTTCAGCGTG TTGGCGCACT


 


701
TCGCCATCGC CGTCGTCAAA ATGGCGCGTT CCACACTGAC CGTCGGCTGG


 


751
TCGAAATACA TACACACCGT CGTCTTTACC CATATGCTGC TGATTGTCTT


 


801
TTTGGCAAAA GCGATGTTTT ATATCAGCTG GTAA






This corresponds to the amino acid sequence <SEQ ID 1228; ORF 294.a>:










a294.pep




1
MRITCAPMSL LSAAVWSIRA VRTSSNRFPA AFRRYSAFRP TIFPKPAGTP


 


51
WHRVRRFKSN RRTRGGKPLK KTYRPRRAEC RCRRARTALS HNIAERARES


 


101
PRRYGKRYAD IGDDSDTIRI RVFRLEYRMS IYAVAHIVHL YCAIAFVGGV


 


151
FFEVLVLSVL HTGRVSCEAR REVEKAMSYR AVRVMPFVVG LLFASGIVMA


 


201
ANRYLSILGE PFATSFGTML TLKILLAFSV LAHFAIAVVK MARSTLTVGW


 


251
SKYIHTVVFT HMLLIVFLAK AMFYISW*






m294/a294 94.9% identity in 277 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1229>:










g295.seq




1
atgctcggga tggcgcggca cgacggccag cagggcatcg ccgcgatatt


 


51
gttgccacgc cgccagcagt ttttccgcct cgtcttcgcc ccgataaacg


 


101
cgcgtgctgc cgcacacggc aaccggccgg cctccgatgc gtttttcaaa


 


151
ctgccccgcc agcgttttca tgtcttcaga cggcatcagg tcgtatttgg


 


201
tattgccgca cacctgcacg gatgccgcgc ccaatttcgc caaccgcgcc


 


251
gcatccgcct ccgtctgcgc cagacagccc gtcagcgaag cggctgcggg


 


301
acggatcagg cggcggactt tcagataacc gttcagcgat ttttccgaca


 


351
gccgcgcatt cgccaaaaac agcggcacac ccgctcgccg gcattccttc


 


401
atcagattgg gccagatttc ggtttccatc aaaatgccga acatcgggcg


 


451
gtgttcgcgc aaaaactgcc gtacccacgt ttttttgtca tacggaagat


 


501
agcggcattg cgcatcggga aacagaactt gcgcggtttc ccgtcccgtc


 


551
ggggtcatct gcgtcatcag cagcggcgca tcgggaaaac gccgccgcaa


 


601
ctcgcgtatc aagggctggg cggcacgcgt ttctccgacc gaaacggcgt


 


651
gtatccaaac cgcgccggta acgggattcg gatgcggctt gccgaaacgc


 


701
tcgtccctat gcgcccggta tgccggggca cttccggagc gtttgtccaa


 


751
ataacgccgt atccatatcg gcgcaagcag ccacaataca tcataaagcc


 


801
attggaacat ctttctattt cctgcaaaac aaatgccgtc cgaacggttc


 


851
ggacggcatt tcggcaacgg aatcaaatat cgtag






This corresponds to the amino acid sequence <SEQ ID 1230; ORF 295.ng>:










g295.pep




1
MLGMARHDGQ QGIAAILLPR RQQFFRLVFA PINARAAAHG NRPASDAFFK


 


51
LPRQRFHVFR RHQVVFGIAA HLHGCRAQFR QPRRIRLRLR QTARQRSGCG


 


101
TDQAADFQIT VQRFFRQPRI RQKQRHTRSP AFLHQIGPDF GFHQNAEHRA


 


151
VFAQKLPYPR FFVIRKIAAL RIGKQNLRGF PSRRGHLRHQ QRRIGKTPPQ


 


201
LAYQGLGGTR FSDRNGVYPN RAGNGIRMRL AETLVPMRPV CRGTSGAFVQ


 


251
ITPYPYRRKQ PQYIIKPLEH LSISCKTNAV RTVRTAFRQR NQIS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1231>:










m295.seq




1
ATGCTCGGGA TGGCGCGGCA CGACGACCAG CAGCGCATCG CCGCGATATT


 


51
GTTGCCACGC CGCCAGCAGT TTTTCCGCCT CGTCTTCACC CCGATAAACG


 


101
CGCGTGCTGC CGCACACGGC AACCGGCCGG CCTCCGATGC GTTTTTCAAA


 


151
CTGCCCCGCC AGCGTTTTCA TCTGTTCCGA CGGTATGATG TCGTATTTGG


 


201
TATTGCCGCA CACCTGCACG GATGCCGCGC CCAATTTCGC CAACCGCGCC


 


251
GCATCCGCCT CTGTCTGCGC CAGACACCCC GTCAGCGAAG CGGCGGCAGG


 


301
ACGGATCAGG CGGCGGACTT TCAGATAACC GTTCAACGAT TTTTCCGACA


 


351
GCCGCGCATT CGCCAAAAAC AGCGGCACAC CCGCGCGCCG GCATTCCCTC


 


401
ATCAGGTTGG GCCAGATTTC GGTTTCCATC AAAATGCCGA ACATCGGGCG


 


451
GTGTTCGCGC AAAAACTGCC GTACCCACGT TTTTTTGTCA TACGGAAGAT


 


501
AGCGGCATTG CGCATCGGGA AACAGAACTT GCGCGGTTTC CCGCCCCGTC


 


551
GGGGTCATCT GCGTCATCAG CAGCGGCGCA TCGGGAAAAC GCCGCCGCAA


 


601
CTCGCGTATC AAGGACTGGG CGGCACGCGT TTCTCCGACC GAAACGGCGT


 


651
GTATCCAAAC CGCGCCGGTA ACGGGATTCG GATACGGCTT GCCGAAACGC


 


701
TCGTCCCGAT GCGCCCGATA TGCCGGGGCA CTTCCGGAGC GTTTGTCCAA


 


751
ATAACGCCGT ATCCATATCG GCGCAAGCAG CCACAATACA TCATAAAGCC


 


801
ATTGGAACAT CTTTCTATTT CCTGCAAAAC AAATGCCGTC TGAACGGTTC


 


851
AGACGGCATT TCGGCAACGG AATCAAATAT CGTAG






This corresponds to the amino acid sequence <SEQ ID 1232; ORF 295>:










m295.pep




1
MLGMARHDDQ QRIAAILLPR RQQFFRLVFT PINARAAAHG NRPASDAFFK


 


51
LPRQRFHLFR RYDVVFGIAA HLHGCRAQFR QPRRIRLCLR QTPRQRSGGR


 


101
TDQAADFQIT VQRFFRQPRI RQKQRHTRAP AFPHQVGPDF GFHQNAEHRA


 


151
VFAQKLPYPR FFVIRKIAAL RIGKQNLRGF PPRRGHLRHQ QRRIGKTPPQ


 


201
LAYQGLGGTR FSDRNGVYPN RAGNGIRIRL AETLVPMRPI CRGTSGAFVQ


 


251
ITPYPYRRKQ PQYIIKPLEH LSISCKTNAV XTVQTAFRQR NQIS*






m295/g295 93.9% identity in 294 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1233>:










a295.seq




1
ATGCTCGGGA TGGCGCGGCA CGACGACCAG CAGGGCATCG CCGCGATATT


 


51
GTTGCCACGC CGCCAGCAGT TTTTCCGCCT CGTCTTCACC CCGATAAACG


 


101
CGCGTGCTGC CGCACACGGC AACCTGCCGG TCTCCGATGC GTTTTTCAAA


 


151
CTGCCCCGCC AGCGTTTTCA TCTGTTCCGA CGGCATCAGG TCGTATTTGG


 


201
TATTGCCGCA CACCTGCACG GATGCCGCGC CCAATTTCGC CAACCGCGCC


 


251
GCATCCGCCT CCGTCTGTGC CAGACAGCCC GTCAGCGAAG CGGCGGCAGG


 


301
ACGGATCAGG CTGCGGACTT TCAGATAACC GTTTAGCGAT TTTTCCGACA


 


351
GCCGCGCATT CGCCAAAAAC AGCGGCACAC CCGTGCGCCG GCATTCCTTC


 


401
ATCAGATTGG GCCAGATTTC GGTTTCCATC AAAATGCCGA ACATCGGGCG


 


451
GTGTTCGCGC AAAAACTGCC GTACCCACGT TTTTTTGTCA TACGGAAGAT


 


501
AGCGGCATTG TGCATCAGGA AACAGAACTT GCGCGGTTTC CCGTCCCGTC


 


551
GGGGTCATCT GCGTCATCAG CAGCGGCGCA TCGGGAAAAC GCTGCCGCAA


 


601
CTCGCGTATC AAAGGTTGGG CGGCACGCGT TTCCCCGACC GAAACGGCGT


 


651
GTATCCAAAC CGCGCCGGTA ACGGGATTCG GATACGGCTT GCCGAAACGC


 


701
TCGCCCCGAT GCGCCCGATA TGCAGGGGCA CTTCCGGAGC GTTTGTCCAA


 


751
ATAACGCCGT ATCCATATCG GCGCAAGCAG CCACAATACA TCATAAAGCC


 


801
ATTGGAACAT CTTTCTATTT CCTGCAAAAC AAATGCCGTC CGAACGGTTC


 


851
GGACGGCATT TCGGCAACGG AATCAAATAT CGTAG






This corresponds to the amino acid sequence <SEQ ID 1234; ORF 295.a>:










a295.pep




1
MLGMARHDDQ QGIAAILLPR RQQFFRLVFT PINARAAAHG NLPVSDAFFK


 


51
LPRQRFHLFR RHQVVFGIAA HLHGCRAQFR QPRRIRLRLC QTARQRSGGR


 


101
TDQAADFQIT V*RFFRQPRI RQKQRHTRAP AFLHQIGPDF GFHQNAEHRA


 


151
VFAQKLPYPR FFVIRKIAAL CIRKQNLRGF PSRRGHLRHQ QRRIGKTLPQ


 


201
LAYQRLGGTR FPDRNGVYPN RAGNGIRIRL AETLAPMRPI CRGTSGAFVQ


 


251
ITPYPYRRKQ PQYIIKPLEH LSISCKTNAV RTVRTAFRQR NQIS*






m295/a295 93.2% identity in 294 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1235>:










g297.seq




1
ATGGCTGTCT TCCCACTTTC GGCAAAACAT CGGAAATACG CGCTGCGCGC


 


51
GCTTGCCGTT TCGATTATTC TGGTGtcgGC GGCATACATT GCttcgacag


 


101
aggggaccga gcgcgtcaga ccgcAGCGCG TggaacaaAA ACTGCCGCCG


 


151
CTGTCtTGGg gcggcaacgg CGTtcagacg gcaTATTGGG TGCAGGAGGC


 


201
GGTGCagccg ggggactcgC TGGCGGACGT GCTGGCGCGT TCGGGTATGG


 


251
CGCGGGacga gattgCCcga ATcacGGAAA aataTggcgG CGAAGCCGAT


 


301
TTGCGgcatt tGCGTGCCGA CCAGTCGGTT CATGTTTTGG TCGGCGGCGA


 


351
CGGCAGTGCG CGCGAAGTGC AGTTTTttaC CGACGAAGAC GGCGAGCGCA


 


401
aTctGGTCGC TTTGGAAAAA AAAGGCGGCA TATGGCGGCG GTCGGCTTCT


 


451
GATGCGGATA TGAAGGTTTT GCCGACACTG CGTTCGGTCG TGGTCAAAAC


 


501
GTCGGCGCGC GGTTCGCTGG CGCGGGCGGA AGTGCCCGTC GAAATCCGCG


 


551
AATCCTTAAG CGGGATTTTT GCCGGCCGCT TCAGCCTTGA CGGTTTGAAG


 


601
GAAGGCGATG CCGTGCGCCT GCTTTACGAC AGCCTGTATT TCCACGGGCA


 


651
GCAGGTGGCG GCGGGCGATA TTTTGGCGGC GGAAGTTGTC AAGGGCGGCA


 


701
CAACCCATCA GGCGTTCTAT TACCGTTCGG ACAAGGAAGG CGGAGGGGGC


 


751
GGCAATTATT ACGATGAAGA CGGCAGGGTG TTGCAGGAAA AAGGCGGCTT


 


801
CAACATCgaG CCGCTGGTCT ATACGCGCAT TTCTTCGCCG TTCGGCTACC


 


851
GTATGCACCC CATCCTGCAC ACATGGCGGC TGCACACGGG CATCGATTAT


 


901
GCCGCACCGC AGGGAACGCC GGTCAGGGCT TCCGCCGACG GCGTGATTAC


 


951
CTTTAAAGGC CGGAAGGGCG GATACGGCAA CGCGGTGATG ATACGCCACG


 


1001
CCAACGGTGT GGAAACGCTG TACGCGCACT TGAGCGCGTT TTCGCAGGCA


 


1051
CAAGGCAATG TGCGCGGCGG CGAGGTCATC GGTTTTGTCG GTTCGACAGG


 


1101
GCGTTCGACC GGGCCGCACC TGCATTACGA GGCGCGCATC AACGGGCAGC


 


1151
CCGTCAATCC TGTTTCGGTC GCATTGCCGA CACCCGAATT GACGCAGGCG


 


1201
GACAAGGCGG CGTTTGCCGC GCAGAAACAG AAGGCGGACG CGCTGCTTGC


 


1251
GCGCTTGCGC GGCATACCGG TTACCGTGTC GCAATCGGAT TGA






This corresponds to the amino acid sequence <SEQ ID 1236; ORF 297.ng>:










g297.pep




1
MAVFPLSAKH RKYALRALAV SIILVSAAYI ASTEGTERVR PQRVEQKLPP


 


51
LSWGGNGVQT AYWVQEAVQP GDSLADVLAR SGMARDEIAR ITEKYGGEAD


 


101
LRHLRADQSV HVLVGGDGSA REVQFFTDED GERNLVALEK KGGIWRRSAS


 


151
DADMKVLPTL RSVVVKTSAR GSLARAEVPV EIRESLSGIF AGRFSLDGLK


 


201
EGDAVRLLYD SLYFHGQQVA AGDILAAEVV KGGTTHQAFY YRSDKEGGGG


 


251
GNYYDEDGRV LQEKGGFNIE PLVYTRISSP FGYRMHPILH TWRLHTGIDY


 


301
AAPQGTPVRA SADGVITFKG RKGGYGNAVM IRHANGVETL YAHLSAFSQA


 


351
QGNVRGGEVI GFVGSTGRST GPHLHYEARI NGQPVNPVSV ALPTPELTQA


 


401
DKAAFAAQKQ KADALLARLR GIPVTVSQSD *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1237>:










m297.seq




1
ATGGCTGTCT TCCCACTTTC GGCAAAACAT CGGAAATACG CGCTGCGTGC


 


51
GCTTGCCGTT TCGATTATTT TGGTGTCGGC GGCATACATT GCTTCGACAG


 


101
AGAGGACGGA GCGCGTCAGA CCGCAGCGCG TGGAACAAAA TCTGCCGCCG


 


151
CTGTCTTGGG GCGGCAGCGG CGTTCAGACG GCATATTGGG TGCAGGAGGC


 


201
GGTGCAGCCG GGCGACTCGC TGGCGGACGT GCTGGCGCGT TCGGGTATGG


 


251
CGCGGGACGA GATTGCCCGA ATCACGGAAA AATATGGCGG CGAAGCCGAT


 


301
TTGCGGCATT TGCGTGCCGA CCAGTCGGTT CATGTTTTGG TCGGCGGCGA


 


351
CGGCGGCGCG CGCGAAGTGC AGTTTTTTAC CGACGAAGAC GGCGAGCGCA


 


401
ATCTGGTCGC TTTGGAAAAG AAAGGCGGCA TATGGCGGCG GTCGGCTTCT


 


451
GAGGCGGATA TGAAGGTTTT GCCGACGCTG CGTTCGGTCG TGGTCAAAAC


 


501
GTCGGCGCGC GGTTCGCTGG CGCGGGCGGA AGTGCCCGTC GAAATCCGCG


 


551
AATCCTTAAG CGGGATTTTC GCCGGCCGCT TCAGCCTTGA CGGTTTGAAG


 


601
GAAGGCGATG CCGTGCGCCT GATGTACGAC AGCCTGTATT TCCACGGGCA


 


651
GCAGGTGGCG GCGGGCGATA TTTTGGCGGC TGAAGTCGTT AAGGGCGGCA


 


701
CAAGGCATCA GGCGTTCTAT TACCGTTCGG ACAAGGAAGG CGGAGGGGGC


 


751
GGCAATTATT ATGATGAAGA CGGCAAGGTG TTGCAGGAAA AAGGCGGCTT


 


801
CAACATCGAG CCGCTGGTCT ATACGCGCAT TTCTTCGCCG TTCGGCTACC


 


851
GTATGCACCC CATCCTGCAC ACATGGCGGC TGCACACGGG CATCGATTAT


 


901
GCCGCACCGC AGGGAACGCC GGTCAGGGCT TCCGCCGACG GCGTGATTAC


 


951
CTTTAAAGGC CGGAAGGGCG GATACGGCAA CGCGGTGATG ATACGCCACG


 


1001
CCAACGGTGT GGAAACGCTG TACGCGCACT TGAGCGCGTT TTCGCAGGCG


 


1051
GAAGGCAATG TGCGCGGCGG CGAGGTCATC GGTTTTGTCG GTTCGACCGG


 


1101
GCGTTCGACC GGGCCGCACC TGCATTACGA GGCGCGCATC AACGGGCAGC


 


1151
CCGTCAATCC TGTTTCGGTC GCATTGCCGA CACCGGAATT GACGCAGGCG


 


1201
GACAAGGCGG CGTTTGCCGC GCAGAAACAG AAGGCGGACG CGCTGCTTGC


 


1251
GCGCTTGCGC GGCATACCGG TTACCGTGTC GCAATCGGAT TGA






This corresponds to the amino acid sequence <SEQ ID 1238; ORF 297>:










m297.pep




1
MAVFPLSAKH RKYALRALAV SIILVSAAYI ASTERTERVR PQRVEQNLPP


 


51
LSWGGSGVQT AYWVQEAVQP GDSLADVLAR SGMARDEIAR ITEKYGGEAD


 


101
LRHLRADQSV HVLVGGDGGA REVQFFTDED GERNLVALEK KGGIWRRSAS


 


151
EADMKVLPTL RSVVVKTSAR GSLARAEVPV EIRESLSGIF AGRFSLDGLK


 


201
EGDAVRLMYD SLYFHGQQVA AGDILAAEVV KGGTRHQAFY YRSDKEGGGG


 


251
GNYYDEDGKV LQEKGGFNIE PLVYTRISSP FGYRMHPILH TWRLHTGIDY


 


301
AAPQGTPVRA SADGVITFKG RKGGYGNAVM IRHANGVETL YAHLSAFSQA


 


351
EGNVRGGEVI GFVGSTGRST GPHLHYEARI NGQPVNPVSV ALPTPELTQA


 


401
DKAAFAAQKQ KADALLARLR GIPVTVSQSD *






m297/g297 97.9% identity in 430 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1239>:










a297.seq




1
ATGGCTGTCT TCCCACTTTC GGCAAAACAT CGGAAATACG CGCTGCGCGC


 


51
GCTTGCCGTT TCGATTATTT TGGTGTCGGC GGCATACATT GCTTCGACAG


 


101
AGAGGACGGA GCGCGTCAGA CCGCAGCGCG TGGAACAAAA ACTGCCGCCG


 


151
CTGTCTTGGG GCGGCAGCGG TGTTCAGACG GCATATTGGG TGCAGGAGGC


 


201
GGTGCAGCCA GGCGACTCGC TGGCGGACGT GCTGGCGCGT TCGGGTATGG


 


251
CGCGGGACGA AATTGCCCGA ATAACGGAAA AATATGGCGG CGAAGCCGAT


 


301
TTGCGGCATT TGCGTGCCGA CCAGTCGGTT CATGTTTTGG TCGGCGGCGA


 


351
CGGCGGCGCG CGCGAAGTGC AGTTTTTTAC CGACGAAGAC GGCGAGCGCA


 


401
ATCTGGTCGC TTTGGAAAAA AAAGGCGGCA TATGGCGGCG GTCGGCTTCT


 


451
GAGGCGGATA TGAAGGTTTT GCCGACGCTG CGTTCGGTCG TGGTCAAAAC


 


501
GTCGGCGCGC GGTTCGCTGG CGCGGGCGGA AGTGCCCGTC GAAATTCGCG


 


551
AATCCTTAAG CGGGATTTTC GCCGGCCGCT TCAGCCTTGA TGGTTTGAAG


 


601
GAAGGCGATG CCGTGCGCCT GATTTACGAC AGCCTGTATT TCCACGGGCA


 


651
GCAGGTGGCG GCGGGCGATA TTCTGGCGGC GGAAGTCGTT AAGGGCGGCA


 


701
CAAGGCATCA GGCGTTCTAT TACCGTTCGG ACAAGGAAGG AGGAGGGGGC


 


751
GGCAATTATT ACGATGAAGA CGGCAGGGTG TTGCAGGAAA AAGGCGGCTT


 


801
CAACATCGAG CCACTGGTCT ATACGCGCAT TTCTTCGCCG TTCGGCTACC


 


851
GTATGCACCC CATCCTGCAC ACTTGGCGGC TGCACACGGG CATCGATTAT


 


901
GCCGCACCGC AGGGAACGCC GGTCAGGGCT TCCGCCGACG GCGTGATTAC


 


951
CTTTAAAGGC CGGAAGGGTG GCTACGGCAA CGCGGTGATG ATACGCCACG


 


1001
CCAACGGTGT GGAAACGCTG TATGCGCACT TGAGCGCGTT TTCTCAGGCA


 


1051
GAAGGCAATG TGCGCGGCGG CGAGGTCATC GGTTTTGTCG GTTCGACCGG


 


1101
GCGTTCGACG GGGCCGCACC TGCATTACGA GGCGCGCATC AATGGGCAGC


 


1151
CCGTCAATCC TGTTTCGGTC GCATTGCCGA CACCCGAATT GACGCAGGCG


 


1201
GACAAGGCGG CGTTTGCCGC GCAGAAACAG AAGGCGGACG CGCTGCTTGC


 


1251
GCGCTTGCGC GGCATACCGG TTACCGTGTC GCAATCGGAT TGA






This corresponds to the amino acid sequence <SEQ ID 1240; ORF 297.a>:










a297.pep




1
MAVFPLSAKH RKYALRALAV SIILVSAAYI ASTERTERVR PQRVEQKLPP


 


51
LSWGGSGVQT AYWVQEAVQP GDSLADVLAR SGMARDEIAR ITEKYGGEAD


 


101
LRHLRADQSV HVLVGGDGGA REVQFFTDED GERNLVALEK KGGIWRRSAS


 


151
EADMKVLPTL RSVVVKTSAR GSLARAEVPV EIRESLSGIF AGRFSLDGLK


 


201
EGDAVRLIYD SLYFHGQQVA AGDILAAEVV KGGTRHQAFY YRSDKEGGGG


 


251
GNYYDEDGRV LQEKGGFNIE PLVYTRISSP FGYRMHPILH TWRLHTGIDY


 


301
AAPQGTPVRA SADGVITFKG RKGGYGNAVM IRHANGVETL YAHLSAFSQA


 


351
EGNVRGGEVI GFVGSTGRST GPHLHYEARI NGQPVNPVSV ALPTPELTQA


 


401
DKAAFAAQKQ KADALLARLR GIPVTVSQSD *






m297/a297 99.3% identity in 430 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1241>:










g298.seq




1
ATGAAAAACT TTCTTTCCCT TTTCGCCTCC ATACTGATGT CTGCCCTGAT


 


51
TGCCGTGTGG TTCAGCCAAA ACCCCATCAA CGCCTACTGG CAGCAGACCT


 


101
ACCACCGCAA CAGCCCGCTC GAACCGCTTG CCGCCTACGG ATGGTGGCGG


 


151
AGCGGAGCGG CGTTGCAAGA AAACGCCTAC GCCCTTTCAG ACGGCATCAA


 


201
AACCTTCCTG TCCGGCGAAA cgccccccac ggCTCAAGAC GGCGGTTCGG


 


251
CAGATATGCC GCCTGAAGCC GCCGCATCCG AAGCCGCCCC GCCGGCCGGC


 


301
GGAACAGAAT GGAAACAAGG CACCGAAGCC GCCGCCGTCC GCAGCGGCGA


 


351
CAAAGTCTTT TTCGCCGGAG ATTCGCTGAT GCAGGGCGTT GCGCCTTTCG


 


401
TGCAAAAAAG CCTGAAACAG CAATACGGCA TCGAATCCGC CAACCTCAGC


 


451
AAACAAAGCA CGGGGCTTTC CTATCCCTCA TTCTTCGACT GGCCGAAAAC


 


501
GATTGAAGAA ACCTTGAAAA AACATCCCGA AATCAGCGTA CTCGCCGTCT


 


551
TCCTCGGCCC GAACGACCCG TGGGATTTCC CCGTCGGCAA ACGCTACCTC


 


601
AAATTCGCTT CCGACGAATG GGCGCAAGAA TACCTGAAAC GCGTCGACCG


 


651
CATCCTTGAA GCCGCACACA CGCACCGCGT CCAAGTCGTC TGGCTCGGCA


 


701
TCCCCTACAT GAAAAAAGTC AAGCTCGACG GTCAGATGCG CTACCTCGAC


 


751
AAACTGCTTT CGGAACACTT GAAAGGCAAA ATCATCCTGA TTCCCACCGC


 


801
GCAAACACTG AGCGGCGGGA AAGgccGCTA CACCGATTCC GTCAACGTCA


 


851
ACGGCAAACC CGTCCGCTAC CGCAGTAAGG ACGGCATACA CTTTACCGCC


 


901
GAAGGACAAA AACTGCTGGC GGAAAAAATA ATGGAAAAAA TCGTTTTTGA


 


951
ACCGAGTACG CAACCATCAA GTACACAGCC ATGA






This corresponds to the amino acid sequence <SEQ ID 1242; ORF 298.ng>:










g298.pep




1
MKNFLSLFAS ILMSALIAVW FSQNPINAYW QQTYHRNSPL EPLAAYGWWR


 


51
SGAALQENAY ALSDGIKTFL SGETPPTAQD GGSADMPPEA AASEAAPPAG


 


101
GTEWKQGTEA AAVRSGDKVF FAGDSLMQGV APFVQKSLKQ QYGIESANLS


 


151
KQSTGLSYPS FFDWPKTIEE TLKKHPEISV LAVFLGPNDP WDFPVGKRYL


 


201
KFASDEWAQE YLKRVDRILE AAHTHRVQVV WLGIPYMKKV KLDGQMRYLD


 


251
KLLSEHLKGK IILIPTAQTL SGGKGRYTDS VNVNGKPVRY RSKDGIHFTA


 


301
EGQKLLAEKI MEKIVFEPST QPSSTQP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1243>:










m298.seq




1
ATGAAAAACT TTCTTTCCCT TTTCTCCTCC ATACTGATGT CTGCCCTGAT


 


51
TGCCGTGTGG TTCAGCCAAA ACCCCATCAA CGCCTACTGG CAGCAGACCT


 


101
ACCACCGCAA CAGCCCGCTC GAACCGCTTG CCGCCTACGG ATGGTGGCGG


 


151
AGCGGTGCGG CGTTGCAAGA AAACGCCTAC GCCCTTTCAG ACGGCATCAA


 


201
AGCCTTCCTG TCCGGCGAAA CGCCGCCGAC GGCTCAAGAC GGCGGTTCGG


 


251
CAGATATGCC GTCTGAAGCC GCCGCATCCG AAGCCGTCCC TCAAACCGGT


 


301
GAAACAGAAT GGAAACAAGA CACCGAAGCC GCCGCCGTCC GCAGCGGCGA


 


351
CAAAGTCTTT TTTGTCGGCG ACTCGCTGAT GCAGGGCGTT GCCCCCTTCG


 


401
TGCAAAAAAG CCTGAAACAG CAATACGGCA TCGAATCCGT CAACCTCAGC


 


451
AAACAAAGCA CGGGGCTGTC CTACCCCTCA TTCTTCGACT GGCCGAAAAC


 


501
GATTGAAGAA ACCCTGCAAA AACATCCCGA AATCAGCGTA CTCGCCGTCT


 


551
TCCTCGGACC GAACGACCCG TGGGATTTCC CCGTCGGCAA ACTCTATCTC


 


601
AAATTCGCTT CCGACGAATG GGCGCAAGAA TACCTGAAAC GTGTCGACCG


 


651
CATCCTTGAA GCCGCACACA CGCACCGCGT CCAAGTCGTC TGGCTCGGCA


 


701
TCCCCTACAT GAAAAAAGCC AAGCTCGACG GACAGATGCG CTACCTAGAC


 


751
AAACTGCTTT CGGAACATTT GAAAGGCAAA ATCATCCTGA TTCCCACCAC


 


801
GCACACCCTG AGCGGCGGGA AAGACCGCTA CACCGACTCC GTCAACGTCA


 


851
ACGGCAAACC CGTCCGCTAC CGCAGCAAGG ACGGCATACA CTTTACCGCC


 


901
GAAGGACAAA AACTGCTGGC GGCAAAAATA ATGGAAAAAA TCGTTTTTGA


 


951
ACCAAGTACG CAACCATCAA GTACACAGCC ATGA






This corresponds to the amino acid sequence <SEQ ID 1244; ORF 298>:










m298.pep




1
MKNFLSLFSS ILMSALIAVW FSQNPINAYW QQTYHRNSPL EPLAAYGWWR


 


51
SGAALQENAY ALSDGIKAFL SGETPPTAQD GGSADMPSEA AASEAVPQTG


 


101
ETEWKQDTEA AAVRSGDKVF FVGDSLMQGV APFVQKSLKQ QYGIESVNLS


 


151
KQSTGLSYPS FFDWPKTIEE TLQKHPEISV LAVFLGPNDP WDFPVGKLYL


 


201
KFASDEWAQE YLKRVDRILE AAHTHRVQVV WLGIPYMKKA KLDGQMRYLD


 


251
KLLSEHLKGK IILIPTTHTL SGGKDRYTDS VNVNGKPVRY RSKDGIHFTA


 


301
EGQKLLAAKI MEKIVFEPST QPSSTQP*






m298/g298 94.8% identity in 327 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1245>:










a298.seq




1
ATGAAAAACT TTCTTTCCCT TTTCGCCTCC ATACTGATGT CTGCCCTGAT


 


51
TGCCGTGTGG TTCAGCCAAA ACCCCATCAA CGCCTACTGG CAGCAGACCT


 


101
ACCACCGCAA CAGCCCGCTC GAACCGCTTG CCGCCTACGG ATGGTGGCGG


 


151
AGCGGTGCGG CATTGCAAGA AAACGCCTAC GCCCTTTCAG ACGGCATCAA


 


201
AGCCTTCCTG TCCGGCGAAA CGCCGCCGAC GGCTCAAGAC GGCGGTTCGG


 


251
CAGATATGCC GTCTGAAGCC GCCGCACCCG AAACCGCCCC TCAAACTGGC


 


301
GAAACAGAAT GGAAACAAAA CACCGAAGCC GCCGCCGTCC GAACAGGGGA


 


351
CAAAGTCTTT TTCGCCGGCG ACTCGCTGAT GCAGGGCGTT GCACCCTTCG


 


401
TGCAAAAAAG CCTGAAACAG CAATACGGCA TCGAATCCGT CAACCTCAGC


 


451
AAACAAAGCA CGGGGCTGTC CTACCCCTCA TTCTTCGACT GGCCGAAAAC


 


501
GATTGAAGAA ACCCTGAAAA AACATCCCGA AATCAGCGTG CTCGCCGTCT


 


551
TCCTCGGTCC GAACGACCCG TGGGATTTCC CCGTTGGCAA ACGCTACCTC


 


601
AAATTCGCTT CCGACGAATG GGCGCAAGAA TACCTGAAAC GCGTCGACCG


 


651
CATCCTTGAA GCCGCACACA CGCACTACGT CCAAGTCGTC TGGCTCGGCA


 


701
TCCCCTACAT GAAAAAAGCC AAGCTCGACG GACAGATGCG CTACCTAGAC


 


751
AAACTGCTTT CGGAATATTT GAAAGGCAAA ATCATCCTGA TTCCCACCGC


 


801
GCACACCCTG AGCGGCGGGA AAGACCGCTA CACCGACTCC GTCAACGTCA


 


851
ACGGCAAACC CGTCCGCTAC CGCAGCAAGG ACGGCATACA CTTTACCGCC


 


901
GAAGGACAAA AACTGCTGGC GGCAAAAATA ATGGAAAAAA TCGTTTTTGA


 


951
ACCAAGTACG CAACCATCAA GTACACAGCC ATGA






This corresponds to the amino acid sequence <SEQ ID 1246; ORF 298.a>:










a298.pep




1
MKNFLSLFAS ILMSALIAVW FSQNPINAYW QQTYHRNSPL EPLAAYGWWR


 


51
SGAALQENAY ALSDGIKAFL SGETPPTAQD GGSADMPSEA AAPETAPQTG


 


101
ETEWKQNTEA AAVRTGDKVF FAGDSLMQGV APFVQKSLKQ QYGIESVNLS


 


151
KQSTGLSYPS FFDWPKTIEE TLKKHPEISV LAVFLGPNDP WDFPVGKRYL


 


201
KFASDEWAQE YLKRVDRILE AAHTHYVQVV WLGIPYMKKA KLDGQMRYLD


 


251
KLLSEYLKGK IILIPTAHTL SGGKDRYTDS VNVNGKPVRY RSKDGIHFTA


 


301
EGQKLLAAKI MEKIVFEPST QPSSTQP*






m298/a298 96.3% identity in 327 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1247>:










g299.seq




1
ATGAACCCCA AACACTTCAT CGCATTTTCC GCCCTGTTCG CCGCCACGCA


 


51
GGCAGAAGCC CTGCCCGTCG CCTCCGTCAG CCCCGACACC GTTACCGTTT


 


101
CCCCGTCCGC CCCCTACACC GATACAAACG GGCTGCTGAC CGACTACGGC


 


151
AACGCCGCCG CCTCGCCTTG GATGAAAAAA CTCCGATCCG TCGCACAAGG


 


201
CAGCGGCGAG GCCTTCCGCA TCCTGCAAAT CGGCGACTCG CATACCGCCG


 


251
GCGACTTCTT TACCGACGCC CTGCGCAAAC GCCTGCAAAA AACATGGGGC


 


301
GACGGCGGCA TAGGCTGGGT TTACCCCGCC AACGTCAAAG GGCAGCGCAT


 


351
GGCGGCCGTC CGTCACAGCG GCAACTGGCA AAGCTTCACC AGCAGGAACA


 


401
ATACCGGAGA TTTCCCGCTC GGCGGCATCC TCGCCCAAAC CGGCAGCGGC


 


451
GGCGGCATGA CCCTGACCGC GTCTGACGGC AAAACCGGCA AACAGCGCGT


 


501
TTCCCTGTTT GCCAAACCGC TGCTCGCCGA ACAAACCCTG ACCGTCAACG


 


551
GCAACACCGT CTCCGCCAAC GGCGGCGGCT GGCAGGTACT GGATACGGGC


 


601
GCGGCACTGC CCCTGGCCAT ACAGACCGAA ATGCCGTGGG ACATCGGCTT


 


651
CATCAACATC GAAAATCCCG CCGGCGGCAT TACCGTTTCC GCGATGGGCA


 


701
TCAACGGCGC ACAATTGACC CAGTGGTCGA AATGGCGTGC CGACCGTATG


 


751
AACGACCTTG CCCAAACCGG CGCCGATTTG GTTATCCTTT CCTACGGCAC


 


801
CAACGAAGCC TTCAACAACA ACATCGACAT TGCCGATACC GAACAAAAAT


 


851
GGCTGGATAC CGTCCGCCAA ATCCGCGACA GCCTGCCCGC CGCCGGCATC


 


901
CTCATCATCG GCGCGCCCGA ATCCCTGAAA AACACGCTCG GCGTATGCGG


 


951
CACGCGCCCC GTCCTCCTGA CCGAAGTCCA ACAGATGCAG CGGCGCGTCG


 


1001
CCCGTCAGGG GCAGACGATG TTTTGGTCTT GGCAAAACGC AATGGGCGGC


 


1051
ATATGCAGCA TGAAAAACTG GCTCAACCAA GGATGGGCCG CCAAAGACGG


 


1101
CGTACACTTC TCCGCCCAAG GCTACCGGCG CGCGGCGGAA ATGCTTGCCG


 


1151
ACAGCCTCGA AGAACTCGTC CGCGCCGCCG CAATCAGGCA ATAA






This corresponds to the amino acid sequence <SEQ ID 1248; ORF 299.ng>:










g299.pep




1
MNPKHFIAFS ALFAATQAEA LPVASVSPDT VTVSPSAPYT DTNGLLTDYG


 


51
NAAASPWMKK LRSVAQGSGE AFRILQIGDS HTAGDFFTDA LRKRLQKTWG


 


101
DGGIGWVYPA NVKGQRMAAV RHSGNWQSFT SRNNTGDFPL GGILAQTGSG


 


151
GGMTLTASDG KTGKQRVSLF AKPLLAEQTL TVNGNTVSAN GGGWQVLDTG


 


201
AALPLAIQTE MPWDIGFINI ENPAGGITVS AMGINGAQLT QWSKWRADRM


 


251
NDLAQTGADL VILSYGTNEA FNNNIDIADT EQKWLDTVRQ IRDSLPAAGI


 


301
LIIGAPESLK NTLGVCGTRP VLLTEVQQMQ RRVARQGQTM FWSWQNAMGG


 


351
ICSMKNWLNQ GWAAKDGVHF SAQGYRRAAE MLADSLEELV RAAAIRQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1249>:










m299.seq




1
ATGAACCCCA AACACCTCAT CGCATTTTCC GCCCTATTCG CCGCCACGCA


 


51
GGCAGAAGCC CTACCTGTCG CCTCCGTCAG CCTCGACACC GTTACCGTTT


 


101
CCCCGTCCGC CCCCTACACC GATACAAACG GGCTGCTGAC CGACTACGGC


 


151
AACGCCTCCG CCTCGCCTTG GATGAAAAAA CTCCAATCCG TCGCACAAGG


 


201
CAGCGGCGAG ACCTTCCGTA TCCTGCAAAT CGGCGACTCG CATACCGCCG


 


251
GCGACTTCTT TACCGACAGC CTGCGCAAAC GCCTGCAAAA AACTTGGGGC


 


301
GACGGCGGCA TAGGCTGGGT TTACCCCGCC AACGTCAAAG GGCAGCGCAT


 


351
GGCGGCCGTC CGGCACAACG GTAACTGGCA AAGCCTCACC AGCAGGAACA


 


401
ACACCGGAGA CTTCCCGCTC GGCGGCATCC TCGCCCACAC CGGCAGCGGC


 


451
GGCAGCATGA CCCTGACCGC ATCGGACGGC ATAGCAAGCA AGCAGCGCGT


 


501
TTCCCTGTTT GCCAAACCCC TGCTTGCCGA ACAAACCCTG ACCGTCAACG


 


551
GCAACACCGT CTCCGCCAAC GGCGGCGGCT GGCAGGTACT GGATACGGGC


 


601
GCGGCACTGC CCCTGACCAT ACACACCGAA ATGCCGTGGG ACATCGGCTT


 


651
CATCAACATC GAAAATCCCG CCGGCGGCAT TACCGTTTCC GCGATGGGCA


 


701
TCAACGGCGC ACAATTAACC CAGTGGTCGA AATGGCGTGC CGACCGTATG


 


751
AACGACCTCG CCCAAACCGG CGCCGATTTG GTTATCCTTT CCTACGGCAC


 


801
CAACGAAGCT TTCAACAACA ACATCGACAT TGCCGACACC GAACAAAAAT


 


851
GGCTGGATAC CGTCCGCCAA ATCCGCGACA GCCTGCCTGC CGCCGGCATC


 


901
CTCATCATCG GCGCACCCGA ATCCCTGAAA AACACGCTCG GCGTATGCGG


 


951
CACACGCCCC GTCCGCCTGA CCGAAGTCCA ACAGATGCAG CGGCGCGTCG


 


1001
CCCGTCAGGG GCAGACGATG TTCTGGTCTT GGCAAAACGC CATGGGCGGC


 


1051
ATATGCAGCA TGAAAAACTG GCTCAACCAA GGATGGGCCG CCAAAGACGG


 


1101
CGTACACTTC TCCGCCAAAG GCTACCGGCG CGCGGCGGAA ATGCTCGCCG


 


1151
ACAGCCTCGA AGAACTCGTC CGCTCCGCTG CAATCAGGCA ATAA






This corresponds to the amino acid sequence <SEQ ID 1250; ORF 299>:










m299.pep




1
MNPKHLIAFS ALFAATQAEA LPVASVSLDT VTVSPSAPYT DTNGLLTDYG


 


51
NASASPWMKK LQSVAQGSGE TFRILQIGDS HTAGDFFTDS LRKRLQKTWG


 


101
DGGIGWVYPA NVKGQRMAAV RHNGNWQSLT SRNNTGDFPL GGILAHTGSG


 


151
GSMTLTASDG IASKQRVSLF AKPLLAEQTL TVNGNTVSAN GGGWQVLDTG


 


201
AALPLTIHTE MPWDIGFINI ENPAGGITVS AMGINGAQLT QWSKWRADRM


 


251
NDLAQTGADL VILSYGTNEA FNNNIDIADT EQKWLDTVRQ IRDSLPAAGI


 


301
LIIGAPESLK NTLGVCGTRP VRLTEVQQMQ RRVARQGQTM FWSWQNAMGG


 


351
ICSMKNWLNQ GWAAKDGVHF SAKGYRRAAE MLADSLEELV RSAAIRQ*






m299/g299 95.5% identity in 397 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1251>:










a299.seq




1
ATGAACCCCA AACACCTCAT CGCATTTTCC GCCCTATTCG CCGCCACGCA


 


51
GGCAGAAGCC CTACCTGTCG CCTCAGTCAG CCTCGACACC GTTACCGTTT


 


101
CCCCGTCCGC CCCCTACACC GATACAAACG GGCTGCTGAC CGACTACGGC


 


151
AACGCCTCCG CCTCGCCTTG GATGAAAAAA CTCCAATCCG TCGCACAAGG


 


201
CAGCGGCGAG ACCTTCCGTA TCCTGCAAAT CGGCGACTCG CATACCGCCG


 


251
GCGACTTCTT TACCGACAGC CTGCGCAAAC GCCTACAAAA AACTTGGGGC


 


301
GACGGCGGCA TAGGCTGGGT TTACCCCGCC AACGTCAAAG GGCAGCGCAT


 


351
GGCGGCCGTC CGGCACAACG GTAACTGGCA AAGCCTCACC AGCAGGAACA


 


401
ACACCGGAGA CTTCCCGCTC GGCGGCATCC TCGCCCACAC CGGCAGCGGC


 


451
GGCAGCATGA CCCTGACCGC ATCGGACGGC ATAGCAAGCA AGCAGCGCGT


 


501
TTCCCTGTTT GCCAAACCCC TGCTTGCCGA ACAAACCCTG ACCGTCAACG


 


551
GCAACACCGT CTCCGCCAAC GGCGGCGGCT GGCAGGTACT GGATACGGGC


 


601
GCGGCACTGC CCCTGACCAT ACACACCGAA ATGCCGTGGG ACATCGGCTT


 


651
CATCAACATC GAAAATCCCG CCGGCGGCAT TACCGTTTCC GCGATGGGCA


 


701
TCAACGGCGC ACAATTAACC CAGTGGTCGA AATGGCGTGC CGACCGTATG


 


751
AACGACCTTG CCCAAACCGG CGCCGATCTA GTCATCCTTG CCTACGGTAC


 


801
CAACGAAGCC TTCGGCGACA ACATCGACAT TGCCGATACC GAACAGAAAT


 


851
GGCTGGATAC CGTCCGCCAA ATCCGCGACA GCCTACCTGC CGCCGGCATC


 


901
CTCATCATCG GCGCGCCCGA ATCCCTGAAA AACACGCTCG GCGTATGCGG


 


951
CACACGCCCC GTCCGCCTGA CCGAAGTCCA ACAGATGCAG CGGCGCATCG


 


1001
CCCGTCAGGG GCAGACGATG TTCTGGTCTT GGCAAAACGC GATGGGCGGC


 


1051
GTTTGCAGCA TGAAAAACTG GCTCAACCAC GGATGGGCCG CCAAAGACGG


 


1101
CGTACACTTT TCCGCCAAAG GCTACCAACG GTCGGCGGAA ATGCTCGCCG


 


1151
ACAGCCTCGA AGAACTCGTC CGCTCCGCTG CAATCAGGCA ATAA






This corresponds to the amino acid sequence <SEQ ID 1252; ORF 299.a>:










a299.pep




1
MNPKHLIAFS ALFAATQAEA LPVASVSLDT VTVSPSAPYT DTNGLLTDYG


 


51
NASASPWMKK LQSVAQGSGE TFRILQIGDS HTAGDFFTDS LRKRLQKTWG


 


101
DGGIGWVYPA NVKGQRMAAV RHNGNWQSLT SRNNTGDFPL GGILAHTGSG


 


151
GSMTLTASDG IASKQRVSLF AKPLLAEQTL TVNGNTVSAN GGGWQVLDTG


 


201
AALPLTIHTE MPWDIGFINI ENPAGGITVS AMGINGAQLT QWSKWRADRM


 


251
NDLAQTGADL VILAYGTNEA FGDNIDIADT EQKWLDTVRQ IRDSLPAAGI


 


301
LIIGAPESLK NTLGVCGTRP VRLTEVQQMQ RRIARQGQTM FWSWQNAMGG


 


351
VCSMKNWLNH GWAAKDGVHF SAKGYQRSAE MLADSLEELV RSAAIRQ*






m299/a299 98.0% identity in 397 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1253>:










g302.seq




1
ATGCACTCAA TATATTTTTT TAAGGAGAAG CAGATGAGTC AAACCGACGC


 


51
GCGTCGTAGC GGACGATTTT TACGCACAGT CGAATGGCTG GGCAATATGT


 


101
TGCCGCACCC GGTTACGCTT TTTATTATTT TCATTGTGTT ATTGCTGATT


 


151
GCCTCTGCCG TCGGTGCGTA TTTCGGACTA TCCGTCCCCG ATCCGCGTCC


 


201
TGTTGGGGCG AAAGGACGTG CCGATGACGG TTTGATTCAC GTTGTCAGCC


 


251
TGCTCGATGC CGACGGTTTG ATCAAAATCC TGACGCATAC CGTTAAAAAT


 


301
TTCACCGGTT TCGCGCCGTT GGGAACGGTG TTGGTTTCTT TATTGGGCGT


 


351
GGGGATTGCG GAAAAATCGG GCTTGATTTC CGCATTAATG CGCTTATTGC


 


401
TCACAAAATC CCCACGCAAA CTCACTACTT TTATGGTTGT TTTTACAGGG


 


451
ATTTTATCCA ATACGGCTTC TGAATTGGGC TATGTCGTCC TAATCCCTTT


 


501
GTCCGCCGTC ATCTTTCATT CGCTCGGCCG CCATCCGCTT GCCGGTTTGG


 


551
CTGCGGCTTT CGCCGGCGTT TCGGGCGGTT ATTCGGCCAA TCTGTTCTTA


 


601
GGCACAATCG ATCCGCTCTT GGCAGGCATC ACCCAACAGG CGGCGCAAAT


 


651
CATCCATCCC GACTACGTCG TAGGCCCTGA AGCCAACTGG TTTTTTATGG


 


701
CAGCCAGTAC GTTTGTGATT GCTTTGATTG GTTATTTTGT TACTGAAAAA


 


751
ATCGTCGAAC CGCAATTGGG CCCTTATCAA TCAGATTTGT CACAAGAAGA


 


801
AAAAGACATT CGGCATTCCA ATGAAATCAC GCCTTTGGAA TATAAAGGAT


 


851
TAATTTGGGC AGGCGTGGTG TTTGTTGCCT TATCCGCCCT ATTGGCTTGG


 


901
AGCATCGTCC CTGCCGACGG TATTTTGCGT CATCCTGAAA CAGGATTGGT


 


951
TGCCGGTTCG CCGTTTTTAA AATCGATTGT TGTTTTTATT TTCTTGTTGT


 


1001
TTGCGCTGCC GGGCATTGTT TATGGCCGGA TAACCCGAAG TTTGCGCGGC


 


1051
GAACGGGAAG TCGTTAATGC GATGGCCGAA TCGATGAGTA CTTTGGGACT


 


1101
TTATTTGGTC ATCATCTTTT TTGCCGCACA GTTTGTCGCA TTTTTTAATT


 


1151
GGACGAATAT TGGGCAATAT ATTGCCGTTA AAGGGGCGGT GTTCTTAAAA


 


1201
GAAGTCGGCT TGGGCGGCAG TGTGTTGTTT ATCGGTTTTA TTTTAATTTG


 


1251
TGCTTTTATC AATCTGATGA TAGGCTCCGC CTCCGCGCAA TGGGCGGTAA


 


1301
CTGCGCCGAT TTTCGTCCCT ATGCTGATGT TGGCCGGCTA CGCGCCCCAA


 


1351
GTCATTCAAG CCGCTTACCG CATCGGTGAT TCCGTTACCA ATATTATTAC


 


1401
GCCGATGATG AGTTATTTCG GGCTGATTAT GGCGACGGTA ATCAAATACA


 


1451
AAAAAGATGC GGGCGTAGGC ACGCTGATTT CTATGATGTT GCCGTATTCC


 


1501
GCTTTCTTCT TAATTGCATG GATCGCCTTA TTCTGCATTT GGGTATTTGT


 


1551
TTTGGGTCTG CCCGTCGGTC CCGGCACACC CACATTCTAT CCGGTGCCTT


 


1601
AA






This corresponds to the amino acid sequence <SEQ ID 1254; ORF 302.ng>:










g302.pep




1
MHSIYFFKEK QMSQTDARRS GRFLRTVEWL GNMLPHPVTL FIIFIVLLLI


 


51
ASAVGAYFGL SVPDPRPVGA KGRADDGLIH VVSLLDADGL IKILTHTVKN


 


101
FTGFAPLGTV LVSLLGVGIA EKSGLISALM RLLLTKSPRK LTTFMVVFTG


 


151
ILSNTASELG YVVLIPLSAV IFHSLGRHPL AGLAAAFAGV SGGYSANLFL


 


201
GTIDPLLAGI TQQAAQIIHP DYVVGPEANW FFMAASTFVI ALIGYFVTEK


 


251
IVEPQLGPYQ SDLSQEEKDI RHSNEITPLE YKGLIWAGVV FVALSALLAW


 


301
SIVPADGILR HPETGLVAGS PFLKSIVVFI FLLFALPGIV YGRITRSLRG


 


351
EREVVNAMAE SMSTLGLYLV IIFFAAQFVA FFNWTNIGQY IAVKGAVFLK


 


401
EVGLGGSVLF IGFILICAFI NLMIGSASAQ WAVTAPIFVP MLMLAGYAPQ


 


451
VIQAAYRIGD SVTNIITPMM SYFGLIMATV IKYKKDAGVG TLISMMLPYS


 


501
AFFLIAWIAL FCIWVFVLGL PVGPGTPTFY PVP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1255>:










m302.seq




1
ATGCACTCAA TATATTTTTT TAAGGAGAAG CAGATGAGTC AAACCGATAC


 


51
GCAACGGGAC GGACGATTTT TACGCACAGT CGAATGGCTG GGCAATATGT


 


101
TGCCGCATCC GGTTACGCTT TTTATTATTT TCATTGTGTT ATTGCTGATT


 


151
GCCTCTGCCG TCGGTGCGTA TTTCGGACTA TCCGTCCCCG ATCCGCGCCC


 


201
TGTTGGTGCG AAAGGACGTG CCGATGACGG TTTGATTTAC ATTGTCAGCC


 


251
TGCTCAATGC CGACGGTTTT ATCAAAATCC TGACGCATAC CGTTAAAAAT


 


301
TTCACCGGTT TCGCGCCGTT GGGAACGGTG TTGGTTTCTT TATTGGGCGT


 


351
GGGGATTGCG GAAAAATCGG GCTTGATTTC CGCATTAATG CGCTTATTGC


 


401
TCACAAAATC GCCACGCAAA CTCACTACTT TTATGGTTGT TTTTACAGGG


 


451
ATTTTATCTA ATACCGCTTC TGAATTGGGC TATGTCGTCC TAATCCCTTT


 


501
GTCCGCCATC ATCTTTCATT CCCTCGGCCG CCATCCGCTT GCCGGTCTGG


 


551
CTGCGGCTTT CGCCGGCGTT TCGGGCGGTT ATTCGGCCAA TCTGTTCTTA


 


601
AGCACAATCG ATCCGCTCTT GGCATGCATC ACCCATCAGG CGGCGGTCGT


 


651
AGGCCCTGAA GCCAACTGGT TTTTTATGGT AGCCAGTACG TTTGTGATTG


 


701
CTTTGATTGG TTATTTTGTT ACTGAAAAAA TCGTCGAACC GCAATTGGGC


 


751
CCTTATCAAT CAGATTTGTC ACAAGAAGAA AAAGACATTC GGCATTCCAA


 


801
TGAAATCACG CCTTTGGAAT ATAAAGGATT AATTTGGGCT GGCGTGGTGT


 


851
TTGTTGCCTT ATCCGCCCTA TTGGCTTGGA GCATCGTCCC TGCCGACGGT


 


901
ATTTTGCGTC ATCCTGAAAC AGGATTGGTT TCCGGTTCGC CGTTTTTAAA


 


951
ATCGATTGTT GTTTTTATTT TCTTGTTGTT TGCACTGyCG GGCmTTGTTT


 


1001
ATGGmCGGGT AACAGGAAGT TTGCGCGGCG AACAGGAAGT CGTTAATGCG


 


1051
ATGGCCGAAT CGATGAGTAC TCTGGsGCTT TmTTTGswCA kcATCTTTTT


 


1101
TGCCGCACAG TTTGTCGCAT TTTTTAATTG GACGAATATT GGGCAATATA


 


1151
TTGCCGTTAA AGGGGCGACG TTCTTAAAAG AAGTCGGCTT GGGCGGCAGC


 


1201
GTGTTGTTTA TCGGTTTTAT TTTAATTTGT GCTTTTATCA ATCTGATGAT


 


1251
AGGCTCCGCC TCCGCGCAAT GGGCGGTAAC TGCGCCGATT TTCGTCCCTA


 


1301
TGCTGATGTT GGCCGGCTAC GCGCCCGAAG TCATTCAAGC CGCTTACCGC


 


1351
ATCGGTGATT CCGTTACCAA TATTATTACG CCGATGATGA GTTATTTCGG


 


1401
GCTGATTATG GCGACGGTGA TCAAATACAA AAAAGATGCG GGCGTGGGTA


 


1451
CGCTGATTTC TATGATGTTG CCGTATTCCG CTTTCTTCTT GATTGCGTGG


 


1501
ATTGCCTTAT TCTGCATTTG GGTATTTGTT TTGGGCCTGC CCGTCGGTCC


 


1551
CGGCGCGCCC ACATTCTATC CCGCACCTTA A






This corresponds to the amino acid sequence <SEQ ID 1256; ORF 302>:










m302.pep




1
MHSIYFFKEK QMSQTDTQRD GRFLRTVEWL GNMLPHPVTL FIIFIVLLLI


 


51
ASAVGAYFGL SVPDPRPVGA KGRADDGLIY IVSLLNADGF IKILTHTVKN


 


101
FTGFAPLGTV LVSLLGVGIA EKSGLISALM RLLLTKSPRK LTTFMVVFTG


 


151
ILSNTASELG YVVLIPLSAI IFHSLGRHPL AGLAAAFAGV SGGYSANLFL


 


201
STIDPLLACI THQAAVVGPE ANWFFMVAST FVIALIGYFV TEKIVEPQLG


 


251
PYQSDLSQEE KDIRHSNEIT PLEYKGLIWA GVVFVALSAL LAWSIVPADG


 


301
ILRHPETGLV SGSPFLKSIV VFIFLLFALX GXVYGRVTRS LRGEQEVVNA


 


351
MAESMSTLXL XLXXIFFAAQ FVAFFNWTNI GQYIAVKGAT FLKEVGLGGS


 


401
VLFIGFILIC AFINLMIGSA SAQWAVTAPI FVPMLMLAGY APEVIQAAYR


 


451
IGDSVTNIIT PMMSYFGLIM ATVIKYKKDA GVGTLISMML PYSAFFLIAW


 


501
IALFCIWVFV LGLPVGPGAP TFYPAP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 302 shows 94.0% identity over a 533 aa overlap with a predicted ORF (ORF 302.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1257>:










a302.seq




1
ATGCACTCAA TATATTTTTT TAAGGAGAAG CAGATGAGTC AAACCGATAC


 


51
GCAACGGGAC GGACGATTTT TACGCACAGT CGAATGGCTG GGCAATATGT


 


101
TGCCGCACCC GGTTACGCTT TTTATTATTT TCATTGTGTT ATTGCTGATT


 


151
GCCTCTGCCG CCGGTGCGTA TTTCGGACTA TCCGTCCCCG ATCCGCGCCC


 


201
TGTTGGTGCG AAAGGACGTG CCGATGACGG TTTGATTCAC GTTGTCAGCC


 


251
TGCTCGATGC TGACGGTTTG ATCAAAATCC TGACGCATAC CGTTAAAAAT


 


301
TTCACCGGTT TCGCGCCGTT GGGAACGGTG TTGGTTTCTT TATTGGGCGT


 


351
GGGGATTGCG GAAAAATCGG GCTTGATTTC CGCATTAATG CGCTTATTGC


 


401
TCACAAAATC TCCACGCAAA CTCACTACTT TTATGGTTGT TTTTACAGGG


 


451
ATTTTATCTA ATACCGCTTC TGAATTGGGC TATGTCGTCC TAATCCCTTT


 


501
GTCCGCCATC ATCTTTCATT CCCTCGGCCG CCATCCGCTT GCCGGTCTGG


 


551
CTGCGGCTTT CGCCGGCGTT TCGGGCGGTT ATTCGGCCAA TCTGTTCTTA


 


601
GGCACAATCG ATCCGCTCTT GGCAGGCATC ACCCAACAGG CGGCGCAAAT


 


651
CATCCATCCC GACTACGTCG TAGGCCCTGA AGCCAACTGG TTTTTTATGG


 


701
TAGCCAGTAC GTTTGTGATT GCTTTGATTG GTTATTTTGT TACTGAAAAA


 


751
ATCGTCGAAC CGCAATTGGG CCCTTATCAA TCAGATTTGT CACAAGAAGA


 


801
AAAAGACATT CGACATTCCA ATGAAATCAC GCCTTTGGAA TATAAAGGAT


 


851
TAATTTGGGC TGGCGTGGTG TTTGTTGCCT TATCCGCCCT ATTGGCTTGG


 


901
AGCATCGTCC CTGCCGACGG TATTTTGCGT CATCCTGAAA CAGGATTGGT


 


951
TTCCGGTTCG CCGTTTTTAA AATCAATTGT TGTTTTTATT TTCTTGTTGT


 


1001
TTGCACTGCC GGGCATTGTT TATGGCCGGG TAACCCGAAG TTTGCGCGGC


 


1051
GAACAGGAAG TCGTTAATGC GATGGCCGAA TCGATGAGTA CTCTGGGGCT


 


1101
TTATTTGGTC ATCATCTTTT TTGCCGCACA GTTTGTCGCA TTTTTTAATT


 


1151
GGACGAATAT TGGGCAATAT ATTGCCGTTA AAGGGGCGAC GTTCTTAAAA


 


1201
GAAGTCGGCT TGGGCGGCAG CGTGTTGTTT ATCGGTTTTA TTTTAATTTG


 


1251
TGCTTTTATC AATCTGATGA TAGGCTCCGC CTCCGCGCAA TGGGCGGTAA


 


1301
CTGCGCCGAT TTTCGTCCCT ATGCTGATGT TGGCCGGCTA CGCGCCCGAA


 


1351
GTCATTCAAG CCGCTTACCG CATCGGTGAT TCCGTTACCA ATATTATTAC


 


1401
GCCGATGATG AGTTATTTCG GGCTGATTAT GGCGACGGTG ATCAAATACA


 


1451
AAAAAGATGC GGGCGTGGGT ACGCTGATTT CTATGATGTT GCCGTATTCC


 


1501
GCTTTCTTCT TGATTGCGTG GATTGCCTTA TTCTGCATTT GGGTATTTGT


 


1551
TTTGGGCCTG CCCGTCGGTC CCGGCGCGCC CACATTCTAT CCCGCACCTT


 


1601
AA






This corresponds to the amino acid sequence <SEQ ID 1258; ORF 302.a>:










a302.pep




1
MHSIYFFKEK QMSQTDTQRD GRFLRTVEWL GNMLPHPVTL FIIFIVLLLI


 


51
ASAAGAYFGL SVPDPRPVGA KGRADDGLIH VVSLLDADGL IKILTHTVKN


 


101
FTGFAPLGTV LVSLLGVGIA EKSGLISALM RLLLTKSPRK LTTFMVVFTG


 


151
ILSNTASELG YVVLIPLSAI IFHSLGRHPL AGLAAAFAGV SGGYSANLFL


 


201
GTIDPLLAGI TQQAAQIIHP DYVVGPEANW FFMVASTFVI ALIGYFVTEK


 


251
IVEPQLGPYQ SDLSQEEKDI RHSNEITPLE YKGLIWAGVV FVALSALLAW


 


301
SIVPADGILR HPETGLVSGS PFLKSIVVFI FLLFALPGIV YGRVTRSLRG


 


351
EQEVVNAMAE SMSTLGLYLV IIFFAAQFVA FFNWTNIGQY IAVKGATFLK


 


401
EVGLGGSVLF IGFILICAFI NLMIGSASAQ WAVTAPIFVP MLMLAGYAPE


 


451
VIQAAYRIGD SVTNIITPMM SYFGLIMATV IKYKKDAGVG TLISMMLPYS


 


501
AFFLIAWIAL FCIWVFVLGL PVGPGAPTFY PAP*






m302/a302 96.1% identity in 533 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1259>:










g305.seq




1
ATGGATTTTT TGATTGTCCT GAAAGCCCTG ATGATGGGCT TGGTAGAAGG


 


51
TTTTACCGAA TTTTTACCGA TTTCCAGCAC CGGACATTTG ATTGTGTTCG


 


101
GCAATCTGAT TGGTTTTCAC AGCAATCACA AGGTTTTTGA AATTGCCATC


 


151
CAGCTCGGTG CGGTTTTGGC GGTAGTGTTT GAATACCGGC AGCGTTTCAG


 


201
CAATGTGTTG CATGGCGTGG GAAAAGACCG GAAAGCCAAC CGTTTCGTCC


 


251
TCAATCTTGC CATTGCTTTT ATACCTGCCG CCGTGATGGG GCTGTTGTTC


 


301
GACAAACAAA TCAAAGAGTA TCTGTTTAAC CCCTTGAGTG TTGCAGTCAT


 


351
GCTGGTTTTG GGCGGTTTTT TTATTTTGTG GGTGGAGAAA CGCCAAAGCC


 


401
GAGCAGAGCC TAAAATTGCC GATGTTGATG CATTGCGTCC GATTGATGCG


 


451
TTGATGATCG GTGTTGCCCA AGTGTTTGCA CTGGTTCCGG GTACGTCCCG


 


501
TTCGGGCAGT ACGGTTATGG GCGGGATGCT TTGGGGAATC GAGCGGAAAA


 


551
CGGCAACGGA GTTTTCATTT TTCTTGGCCG TTCCGATGAT GGTTGCAGCA


 


601
ACGGCTTATG ATGTCCTGAA ACATTACCGA TTTTTCACCC TGCATGATGT


 


651
CGGTTTGATT TTGATAGGCT TTATTGCCGC TTTTGTTTCC GGTTTGGTAG


 


701
CGGTTAAAGC ACTGCTGAAG TTTGTTTCCA AGAAAAACTA TATCCCGTTT


 


751
GCCTATTACC GCATTGTTTT CGGCATTGTC ATCATAATAT TGTGGTTGTC


 


801
GGGCTGGATA AGTTGGGAAT GA






This corresponds to the amino acid sequence <SEQ ID 1260; ORF 305.ng>:










g305.pep




1
MDFLIVLKAL MMGLVEGFTE FLPISSTGHL IVFGNLIGFH SNHKVFEIAI


 


51
QLGAVLAVVF EYRQRFSNVL HGVGKDRKAN RFVLNLAIAF IPAAVMGLLF


 


101
DKQIKEYLFN PLSVAVMLVL GGFFILWVEK RQSRAEPKIA DVDALRPIDA


 


151
LMIGVAQVFA LVPGTSRSGS TVMGGMLWGI ERKTATEFSF FLAVPMMVAA


 


201
TAYDVLKHYR FFTLHDVGLI LIGFIAAFVS GLVAVKALLK FVSKKNYIPF


 


251
AYYRIVFGIV IIILWLSGWI SWE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1261>:









m305.seq (partial)










1
AtGGATTTTC TGATTGTCCT GAAAGCCCTG ATGATGGGCT TGGTAGAAGG



 


51
TTTTACCGAA TTTTTACCGA TTTCCAGCAC CGGACATTTG ATTGTGTTCG


 


101
GCAATCTGAT TGGTTTTCAC AGCAATCACA AGGTTTTTGA AATTGCCATC


 


151
CAGCTCGGTG CAGTTTTGGC GGTAGTGTTT GAATACCGGC AACGTTTCAG


 


201
CAATGTGTTG CACGGCTTGG GAAAAGACCG GAAAGCCAAC CGCTTCGTCC


 


251
TTAATCTTGC CATTGCTTTT ATACCTGCCG CCGTGATGGG GCTGTTGTTC


 


301
GGCAwACAAA TCAAAGAGyA TCTGTTTAAC CCCTTGAGTG TTGCAGTCAT


 


351
GCTGGTTyTG GrCGGTTTTT yTATTTTGTG GGTGGAGAAA CGCCAAAGCC


 


401
GAGCAGAGCC TAAAATTGCC GATGTTGATG CATTGCGTCC GATTGATGCC


 


451
TTGATGATCG GCGTTGCCCA AGTGTTTGCA CTGGTTCCGG GTACGTCCCG


 


501
TTCGGGCAGT ACGATTATGG GCGGGATGCT TTGGGGCATC GAACGGAAAA


 


551
CTGCGACAGA ATTCTCGTTT TTCTTGGCTG TGCCGATGAT GGTTGCCGCA


 


601
ACGGCTTATG ATGTCCTGAA ACATTACCGA TTTTTCACCC TGCATGATGT


 


651
CGGTTTGATT CTGATAGGCT TTATTGCTGC CTTTGTTTCA GGCTTGGTAG


 


701
CGGTAAAAGC GTTGCTGAGG TTTGTTTCGG GTAC...






This corresponds to the amino acid sequence <SEQ ID 1262; ORF 305>:









m305.pep (partial)










1
MDFLIVLKAL MMGLVEGFTE FLPISSTGHL IVFGNLIGFH SNHKVFEIAI



 


51
QLGAVLAVVF EYRQRFSNVL HGLGKDRKAN RFVLNLAIAF IPAAVMGLLF


 


101
GXQIKEXLFN PLSVAVMLVL XGFXILWVEK RQSRAEPKIA DVDALRPIDA


 


151
LMIGVAQVFA LVPGTSRSGS TIMGGMLWGI ERKTATEFSF FLAVPMMVAA


 


201
TAYDVLKHYR FFTLHDVGLI LIGFIAAFVS GLVAVKALLR FVSG...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 305 shows 96.7% identity over a 243 aa overlap with a predicted ORF (ORF 305.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1263>:










a305.seq




1
ATGGATTTTC TGATTGTCCT GAAAGCCCTG ATGATGGGCT TGGTAGAAGG


 


51
TTTTACCGAA TTTTTACCGA TTTCCAGCAC CGGACATTTG ATTGTGTTCG


 


101
GCAATCTGAT TGATTTTCAC AGCAATCACA AGGTTTTTGA AATTACCATC


 


151
CAGCTCGGTG CGGTTTTGGC GGTAGTGTTT GAATACCGGC AGCGTTTCAG


 


201
CAATGTGTTG CATGGCGTGG GAAAAGACCG GAAAGCCAAC CGTTTCGTCC


 


251
TTAATCTTGC CATTGCTTTT ATACCTGCCG CCGTGATGGG GCTGTTGTTC


 


301
GGCAAACAAA TCAAAGAGTA TCTGTTTAAC CCCTTGAGTG TTGCAGTCAT


 


351
GCTGGTTTTG GGCGGTTTTT TTATTTTGTG GGTGGAGAAA CGCCAAAGCC


 


401
GAGCAGAGCC TAAAATTGTC GATGTTGATG CATTGCGTCC GATTGATGCG


 


451
TTGATGATCG GCGTTGCCCA AGTGTTTGCA CTGGTTCCAG GTACGTCCCG


 


501
TTCGGGCAGT ACGATTATGG GCGGGATGCT TTGGGGAATC GAGCGGAAAA


 


551
CGGCAACGGA GTTTTCATTT TTCTTGGCCG TTCCGATGAT GGTTGCAGCA


 


601
ACGGCTTATG ATGTCCTGAA GCATTACCGG TTTTTCACCC TGCATGATGT


 


651
CGGTTTGATT TTGATTGGCT TTGTTGCTGC CTTTGTTTCA GGCTTGGTGG


 


701
CGGTCAAAGC GTTGCTGAGG TTTGTTTCCA AGAAAAATTA TATTCCTTTT


 


751
GCCTATTACC GCATTGTTTT TGGTATTGCC ATCATTATAT TGTGGCTGTC


 


801
AGGCTGGATA AGTTGGGAAT GA






This corresponds to the amino acid sequence <SEQ ID 1264; ORF 305.a>:










a305.pep




1
MDFLIVLKAL MMGLVEGFTE FLPISSTGHL IVFGNLIDFH SNHKVFEITI


 


51
QLGAVLAVVF EYRQRFSNVL HGVGKDRKAN RFVLNLAIAF IPAAVMGLLF


 


101
GKQIKEYLFN PLSVAVMLVL GGFFILWVEK RQSRAEPKIV DVDALRPIDA


 


151
LMIGVAQVFA LVPGTSRSGS TIMGGMLWGI ERKTATEFSF FLAVPMMVAA


 


201
TAYDVLKHYR FFTLHDVGLI LIGFVAAFVS GLVAVKALLR FVSKKNYIPF


 


251
AYYRIVFGIA IIILWLSGWI SWE*






m305/a305 96.3% identity in 243 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1265>:










g306.seq




1
ATGTTTATGA ACAAATTTTC CCAATCCGGA AAAGGTCTGT CCGGTTTCTT


 


51
CTTCGGTTTG ATACTGGCAA CGGTCATTAT TGCCGGTATT TTGCTTTATC


 


101
TGAACCAGGG CGGTCAAAAT GCGTTCAAAA TCCCGGCTCC GTCGAAGCAG


 


151
CCTGCAGAAA CGGAAATCCT GAAACTGAAA AACCAGCCTA AGGAAGACAT


 


201
CCAACCTGAA CCGGCCGATC AAAACGCCTT GTCCGAACCG GATGTTGCGA


 


251
AAGAGGCAGA GCAGTCGGAT GCGGAAAAAG CTGCCGACAA GCAGCCCGTT


 


301
GCCGACAAAG CCGACGAGGT TGAAGAAAAG GCGGGCGAGC CGGAACGGGA


 


351
AGAGCCGGAC GGACAGGCAG TGCGCAAGAA AGCACTGACT GAAGAGCGTG


 


401
AACAAACCGT CAGGGAAAAA GCGCAGAAGA AAGATGCCGA AACGGTTAAA


 


451
AAAAAAGCGG TAAAACCGTC TAAAGAAACA GAGAAAAAAG CTTCAAAAGA


 


501
AGAGAAAAAG GCGGCGAAAG AAAAAGTTGC ACCCAAACCG ACCCCGGAAC


 


551
AAATCCTCAA CAGCCGCAGT ATCGAAAAAG CGCGTAGTGC CGCTGCCAAA


 


601
GAAGTGCAGA AAATGAAAAA CTTTGGGCAA GGCGGAAGCC AACGCATTAT


 


651
CTGCAAATGG GCGCGTATGC CGAACCCCGG AGCGCGGAAG GGCAGCGTGC


 


701
CAAACTGGCA ATCTTGGGCA TATCTTCCGA AGTGGTCGGC TATCAGGCGG


 


751
GACATAAAAC GCTTTACCGC GTGCAAAGCG GCAATATGTC CGCCGATGCG


 


801
GTGA






This corresponds to the amino acid sequence <SEQ ID 1266; ORF 306.ng>:










g306.pep




1
MFMNKFSQSG KGLSGFFFGL ILATVIIAGI LLYLNQGGQN AFKIPAPSKQ


 


51
PAETEILKLK NQPKEDIQPE PADQNALSEP DVAKEAEQSD AEKAADKQPV


 


101
ADKADEVEEK AGEPEREEPD GQAVRKKALT EEREQTVREK AQKKDAETVK


 


151
KKAVKPSKET EKKASKEEKK AAKEKVAPKP TPEQILNSRS IEKARSAAAK


 


201
EVQKMKNFGQ GGSQRIICKW ARMPNPGARK GSVPNWQSWA YLPKWSAIRR


 


251
DIKRFTACKA AICPPMR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1267>:









m306.seq (partial)










1
..GGTTTGTTCT TCGGTTTGAT ACTGGCGACG GTCATTATTG CCGGTATTTT



 


51
  GTTTTATCTG AACCAGAGCG GTCAAAATGC GTTCAAAATC CCGGCTTCGT


 


101
  CGAAGCAGCC TGCAGAAACG GAAATCCTGA AACCGmAwAA CCAGCyTAAG


 


151
  GAAGACATCC AACCTGAwCC GGCCGATCAA AACGCCTTGT CCGAACCGGA


 


201
  TGCTGCGACA GAGGCAGAGC AGTCGGATGC GGAAAAwGCT GCCGACAAGC


 


251
  AGCCCGTTGC CGATAAAGCC GACGAGGTTG AAGAAAAGGC GGGCGAGCCG


 


301
  GAACGGGAAG AGCCGGACGG ACAGGCAGTG CGTAAGAAAG CGCTGACGGA


 


351
  AGAGCGTGAA CAAACCGTCA GGGAAAAAGC GCAGAAGAAA GATGCCGAAA


 


401
  CGGTTAAAAw ACAAGCGGTA AAACCGTCTA AAGAAACAGA GAAAAAAGCT


 


451
  TCAAAAGAAG AGAAAAAGGC GGCGAAGGAA AAAGTTGCAC CCAAACCAAC


 


501
  CCCGGAACAA ATCCTCAACA GCGGCAGCAT CGAAAAAGCG CGCAGTGCCG


 


551
  CCGCCAAAGA AGTGCAGAAA ATGAAAACGC CGACAAGGCG GAAGCAACGC


 


601
  ATTATCTGCA AATGGGCGCG TATGCCGACC GTCAGAGCGC GGAAGGGCAG


 


651
  CGTGCCAAAC TGGCAATCTT GGGCATATCT TCCAAGGTGG TCGGTTATCA


 


701
  GGCGGGACAT AAAACGCTTT ACCGGGTGCA AAGCGGCAAT ATGTCTGCCG


 


751
  ATGCGGTGA






This corresponds to the amino acid sequence <SEQ ID 1268; ORF 306>:









m306.pep (partial)










1
..GLFFGLILAT VIIAGILFYL NQSGQNAFKI PASSKQPAET EILKPXNQXK



 


51
  EDIQPXPADQ NALSEPDAAT EAEQSDAEXA ADKQPVADKA DEVEEKAGEP


 


101
  EREEPDGQAV RKKALTEERE QTVREKAQKK DAETVKXQAV KPSKETEKKA


 


151
  SKEEKKAAKE KVAPKPTPEQ ILNSGSIEKA RSAAAKEVQK MKTPTRRKQR


 


201
  IICKWARMPT VRARKGSVPN WQSWAYLPRW SVIRRDIKRF TGCKAAICLP


 


251
  MR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 306 shows 88.9% identity over a 253 aa overlap with a predicted ORF (ORF 306.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1269>:










a306.seq




1
ATGTTTATGA ACAAATTTTC CCAATCCGGA AAAGGTCTGT CCGGTTTTTT


 


51
CTTCGGTTTG ATACTGGCGA CGGTCATTAT TGCCGGTATT TTGTTTTATC


 


101
TGAACCAGAG CGGTCAAAAT GCGTTCAAAA TCCCGGTTCC GTCGAAGCAG


 


151
CCTGCAGAAA CGGAAATCCT GAAACCGAAA AACCAGCCTA AGGAAGACAT


 


201
CCAACCTGAA CCGGCCGATC AAAACGCCTT GTCCGAACCG GATGCTGCGA


 


251
AAGAGGCAGA GCAGTCGGAT GCGGAAAAAG CTGCCGACAA GCAGCCCGTT


 


301
GCCGACAAAG CCGACGAGGT TGAGGAAAAG GCGGACGAGC CGGAGCGGGA


 


351
AAAGTCGGAC GGACAGGCAG TGCGCAAGAA AGCACTGACG GAAGAGCGTG


 


401
AACAAACCGT CGGGGAAAAA GCGCAGAAGA AAGATGCCGA AACGGTTAAA


 


451
AAACAAGCGG TAAAACCATC TAAAGAAACA GAGAAAAAAG CTTCAAAAGA


 


501
AGAGAAAAAG GCGGAGAAGG AAAAAGTTGC ACCCAAACCG ACCCCGGAAC


 


551
AAATCCTCAA CAGCGGCAGC ATCGAAAAAG CGCGCAGTGC CGCTGCCAAA


 


601
GAAGTGCAGA AAATGAAAAC GCCGACAAGG CGGAAGCAAC GCATTATCTG


 


651
CAAATGGGCG CGTATGCCGA CCGCCGGAGC GCGGAAGGGC AGCGTGCCAA


 


701
ACTGGCAATC TTGGGCATAT CTTCCAAGGT GGTCGGTTAT CAGGCGGGAC


 


751
ATAAAACGCT TTACCGGGTG CAAAGCGGCA ATATGTCTGC CGATGCGGTG


 


801
A






This corresponds to the amino acid sequence <SEQ ID 1270; ORF 306.a>:










a306.pep




1
MFMNKFSQSG KGLSGFFFGL ILATVIIAGI LFYLNQSGQN AFKIPVPSKQ


 


51
PAETEILKPK NQPKEDIQPE PADQNALSEP DAAKEAEQSD AEKAADKQPV


 


101
ADKADEVEEK ADEPEREKSD GQAVRKKALT EEREQTVGEK AQKKDAETVK


 


151
KQAVKPSKET EKKASKEEKK AEKEKVAPKP TPEQILNSGS IEKARSAAAK


 


201
EVQKMKTPTR RKQRIICKWA RMPTAGARKG SVPNWQSWAY LPRWSVIRRD


 


251
IKRFTGCKAA ICLPMR*






m306/a306 93.7% identity in 252 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1271>:










g307.seq




1
atgaaaacct tcttcaaaac cctttcgacc gcgtcactcg cgctcatcct


 


51
cgcagcctgc ggcggtcaaa aagacagcgc gcccgcagcc tctgccgccg


 


101
ccccttctgc cgataacggc gcggcgaaaa aagaaatcgt cttcggcacg


 


151
accgtgggcg acttcggcga tatggtcaaa gaacaaatcc aagccgagct


 


201
ggagaaaaaa ggctacaccg tcaaattggt cgaatttacc gactatgtgc


 


251
gcccgaatct ggcattggcg gagggcgagt tggacatcaa cgtcttccaa


 


301
cacaaaccct atcttgacga tttcaaaaaa gaacacaacc tggacatcac


 


351
cgaagccttc caagtgccga ccgcgccttt gggactgtat ccgggcaaac


 


401
tgaaatcgct ggaagaagtc aaagacggca gcaccgtatc cgcgcccaac


 


451
gacccgtcca acttcgcacg cgccttggtg atgctgaacg aactgggttg


 


501
gatcaaactc aaagacggca tcaatccgct gaccgcatcc aaagccgaca


 


551
tcgcggaaaa cctgaaaaac atcaaaatcg tcgagcttga agccgcacaa


 


601
ctgccgcgca gccgcgccga cgtggatttt gccgtcgtca acggcaacta


 


651
cgccataagc agcggcatga agctgaccga agccctgttc caagagccga


 


701
gctttgccta tgtcaactgg tctgccgtca aaaccgccga caaagacagc


 


751
caatggctta aagacgtaac cgaggcctat aactccgacg cgttcaaagc


 


801
ctacgcgcac aaacgcttcg agggctacaa ataccctgcc gcatggaatg


 


851
aaggcgcagc caaataa






This corresponds to the amino acid sequence <SEQ ID 1272; ORF 307.ng>:










g307.pep




1
MKTFFKTLST ASLALILAAC GGQKDSAPAA SAAAPSADNG AAKKEIVFGT


 


51
TVGDFGDMVK EQIQAELEKK GYTVKLVEFT DYVRPNLALA EGELDINVFQ


 


101
HKPYLDDFKK EHNLDITEAF QVPTAPLGLY PGKLKSLEEV KDGSTVSAPN


 


151
DPSNFARALV MLNELGWIKL KDGINPLTAS KADIAENLKN IKIVELEAAQ


 


201
LPRSRADVDF AVVNGNYAIS SGMKLTEALF QEPSFAYVNW SAVKTADKDS


 


251
QWLKDVTEAY NSDAFKAYAH KRFEGYKYPA AWNEGAAK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1273>:









m307.seq (partial)










1
..CAATGGCTTA AAGACGTAAC CGAGGCCTAT AACTCCGACG CGTTCAAAGC



 


51
  CTACGCGCAC AAACGCTTCG AGGGCTACAA ATCCCCTGCC GCATGGAATG


 


101
  AAGGCGCAGC CAAATAA






This corresponds to the amino acid sequence <SEQ ID 1274; ORF 307>:








m307.pep (partial)








1
..QWLKDVTEAY NSDAFKAYAH KRFEGYKSPA AWNEGAAK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 307 shows 97.4% identity over a 38 aa overlap with a predicted ORF (ORF 307.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1275>:










a307.seq




1
ATGAAAACCT TCTTCAAAAC CCTTTCCGCC GCCGCACTCG CGCTCATCCT


 


51
CGCCGCCTGC GGCGGTCAAA AAGATAGCGC GCCCGCCGCA TCCGCTTCTG


 


101
CCGCCGCCGA CAACGGCGCG GCGAAAAAAG NAATCGTCTT CGGCACGACC


 


151
GTCGGCGACT TCGGCGATAT GGTCAAAGAA CAAATCCAAC CCGAGCTGGA


 


201
GAAAAAAGGC TACACCGTCA AACTGGTCGA GTTTACCGAC TATGTGCGCC


 


251
CGAATCTGGC ATTGGCTGAG GGCGAGTNGG ACATCAACGT CTTCCAACAC


 


301
AAACCCTATC TTGACGACTT CAAAAAAGAA CACAATCTGG ACATCACCGA


 


351
AGTCTTCCAA GTGCCGACCG CGCCTTTGGG ACTGTACCCG GGCAAGCTGA


 


401
AATCGCTGGA AGAAGTCAAA GACGGCAGCA CCGTATCCGC GCCCAACGAC


 


451
CCGTCCAACT TCGCCCGCGT CTTGGTGATG CTCGACGAAC TGGGTTGGAT


 


501
CAAACTCAAA GANGGCATCA ATCCGCTGAC CGCATCCAAA GCGGACATTG


 


551
CCGAAAACCT GAAAAACATC AAAATCGTCG AGCTTGAAGC CGCGCAACTG


 


601
CCGCGTAGCC GCGCCGACGT GGATTTTGNC GTCGTCAACG GCAANTACGC


 


651
CATAAGCAGC GGCATGAAGC TGACCGAAGC CCTGTTCCAA GAACCGAGCT


 


701
TTGCCTATGT CAACTGGTCT GCCGTCAAAA CCGCCGACAA AGACAGCCAA


 


751
TGGCTTAAAG ACGTAACCGA GGCCTATAAC TCCGACGCGT TCAAAGCCTA


 


801
CGCGCACAAA CGCTTCGAGG GCTACAAATC CCCTGCCGCA TGGAATGAAG


 


851
GCGCAGCCAA ATAA






This corresponds to the amino acid sequence <SEQ ID 1276; ORF 307.a>:










a307.pep




1
MKTFFKTLSA AALALILAAC GGQKDSAPAA SASAAADNGA AKKXIVFGTT


 


51
VGDFGDMVKE QIQPELEKKG YTVKLVEFTD YVRPNLALAE GEXDINVFQH


 


101
KPYLDDFKKE HNLDITEVFQ VPTAPLGLYP GKLKSLEEVK DGSTVSAPND


 


151
PSNFARVLVM LDELGWIKLK XGINPLTASK ADIAENLKNI KIVELEAAQL


 


201
PRSRADVDFX VVNGXYAISS GMKLTEALFQ EPSFAYVNWS AVKTADKDSQ


 


251
WLKDVTEAYN SDAFKAYAHK RFEGYKSPAA WNEGAAK*






m307/a307 100.0% identity in 38 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1277>:










g308.seq




1
ATGTTAAATC GGGTATTTTA TCGGATATTG GGTGTTGCCG ACAATTTGTA


 


51
TCCGTGTTTA TCGGATTTCT GTTTTTTCAC TATAATAGCC GGTTTGCCGT


 


101
TGCAGGCGGT TTTATGGGAA AGGCGGATGA TGGTACGGCG TTTGATAATC


 


151
GGCATCAGCG GGGCGAGCGG TTTCCAATAC GGCGTGAAGG CTTTGGAACT


 


201
TTTGCGCGCG CAAGATGTCG AAACGCACCT TGTGGTATCG AAAGGCGCGG


 


251
AGATGGCGCG CGCTTCGGAA ACGGATTATA CGAAAGACGA AGTATATGCC


 


301
TTGGCTGATT TCGTCCATCC GATCGGCAAT ATCGGGGCGT GCATTGCCAG


 


351
CGGTACGTTT AAAACGGACG GGATGCTGGT CGCACCCTGT TCGATGCGGA


 


401
CGCTTGCCTC TGTCGCGCAC GGCTTCGGCG ACAACCTCTT GACGCGTGCG


 


451
GCGGATGTGG TTTTGAAGGA AAGGCGGCGG CTGGTGCTGA TGGTGCGCGA


 


501
AACGCCGCTG AACCTTGCCC ATTTGGACAA TATGAAGCGG GTAACGGAAA


 


551
TGGGCGGCGT GGTGTTTCCC CCTGTTCCTG CGATGTACCG CAAGCCGCAG


 


601
ACGGCGGACG ACATAGTGGC GCACAGTATC GCACACACGC TGTCGCTGTT


 


651
CGGAATCGAT ACGCCGGATT TGGCGGAATG GCAGGGAATG GCGGATTAA






This corresponds to the amino acid sequence <SEQ ID 1278; ORF 308.ng>:










g308.pep




1
MLNRVFYRIL GVADNLYPCL SDFCFFTIIA GLPLQAVLWE RRMMVRRLII


 


51
GISGASGFQY GVKALELLRA QDVETHLVVS KGAEMARASE TDYTKDEVYA


 


101
LADFVHPIGN IGACIASGTF KTDGMLVAPC SMRTLASVAH GFGDNLLTRA


 


151
ADVVLKERRR LVLMVRETPL NLAHLDNMKR VTEMGGVVFP PVPAMYRKPQ


 


201
TADDIVAHSI AHTLSLFGID TPDLAEWQGM AD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1279>:









m308.seq (partial)










1
ATGTTAAATC GGGTATTTTA TCGGATATTG GGTGTTGCCG ACAATTTGTA



 


51
TCCGCGTTTA TCGGATTTCT GTTTTTTCAC TATAATAGCC GGTTTGCCGT


 


101
TGCAGGCGGT TTTATGGGAA AGGCGGATGA TGGTACGGCG TTTGATAATC


 


151
GGCATCAGCG GGGCGAGCGG TTTCCAATAC GGCGTGAAGG CTTTGGAACT


 


201
TTTGCGCGCG CAAGATGTCG AAACGCACCT TGTGGTATCG AAAGGTGCGG


 


251
AGATGGCGCG CGCTTCGGAA ACGGCTTATG CGAGAGACGA GGTATATGCC


 


301
TTGGCGGACT TCGTGCATCC GATCGGCAAT ATCGGGGCGT GCATTGCCAG


 


351
CGGTACGTTT AAAACGGATG GGATGCTGGT CGCCCCCTGT TCGATGCGGA


 


401
CGCTTGCCTC TGTCGCGCAC GGCTTCGGCG ACAATCTGcT GACGCgTGCG


 


451
GCGGATGTGG TTTTGAAGGA AAGGCGGCGG CTGGTGCTGA TGGTGCGCGA


 


501
AACGCCGCTG AACCTTGCCC ATTTGGACAA TATGAAGCGG GwAACGGAAA


 


551
TGGGCGGCGT GGTGTTTCCC CCTGTTCCTG CGATGTACCG CAAACCGCAG


 


601
ACGGCGGACG ACATAGTGGC GCACAGTGTT GCACACGCtT TGTCGCTGTT


 


651
CGGAATCGAT ACGCCGGATT CGGCGGAATG GCArGGAATG gcG...






This corresponds to the amino acid sequence <SEQ ID 1280; ORF 308>:









m308.pep (partial)









1
MLNRVFYRIL GVADNLYPRL SDFCFFTIIA GLPLQAVLWE RRMMVRRLII


 


51
GISGASGFQY GVKALELLRA QDVETHLVVS KGAEMARASE TAYARDEVYA


 


101
LADFVHPIGN IGACIASGTF KTDGMLVAPC SMRTLASVAH GFGDNLLTRA


 


151
ADVVLKERRR LVLMVRETPL NLAHLDNMKR XTEMGGVVFP PVPAMYRKPQ


 


201
TADDIVAHSV AHALSLFGID TPDSAEWQGM A..






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 308 shows 96.5% identity over a 231 aa overlap with a predicted ORF (ORF 308.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1281>:










a308.seq




1
ATGTTAAATC GGATATTTTA TCGGATATTG GGTGTTGCCG ACAATTTGTA


 


51
TCCGTATTTA TCGGATTTCT GTTTTTTCAC TATAATAGCC GGTTTGCCGT


 


101
TGCAGGCGGT TTTATGGGAA AGGCGGATGA TGGTACGGCG TTTGATAATC


 


151
GGCATCAGTG GGGCGAGCGG TTTCCAATAC GGCGTGAAGG CTTTGGANCT


 


201
TTTACGCGCG CAAGATATCG AAACGCACCT TGTGGTATCG AAAGGTGCGG


 


251
AGATGGCGCG CGCTTCGGAA ACGGNTTATG CGAGAGACGA NGTATATGCC


 


301
TTGGCGGACT TNGTGCATCC GATCGGCAAT ATCGGGGCGT GCATTGCCAG


 


351
CGGTACGTTT AAAACGGACG GGATGCTGGT CGCCCCCTGT TCGATGCGGA


 


401
CGCTTGCCTC GGTCGTGCAC GGCTTCGGCG ACAACCTCTT GACGCGTGCG


 


451
GCGGATGTGG TTTTGAAGGA AAGGCGGCGG CTGGTGCTGA TGGTGCGCGA


 


501
AACGCCGCTG AACCTTGCCC ATTTGGACAA TATGAANCGG GTAACGGAAA


 


551
TGGGCGGCGT GGTGTTTCCC CCTGTTCCTG CGATGTACCG CAAACCGCAG


 


601
ACGGCGGACG ACATAGTGGC GCACAGTGTT GCACACGCTT TGTCGCTGTT


 


651
CGGAATCGAT ACGCCGGATT CGGCGGAATG GCAGGGAATG GCGGATTAA






This corresponds to the amino acid sequence <SEQ ID 1282; ORF 308.a>:










a308.pep




1
MLNRIFYRIL GVADNLYPYL SDFCFFTIIA GLPLQAVLWE RRMMVRRLII


 


51
GISGASGFQY GVKALXLLRA QDIETHLVVS KGAEMARASE TXYARDXVYA


 


101
LADXVHPIGN IGACIASGTF KTDGMLVAPC SMRTLASVVH GFGDNLLTRA


 


151
ADVVLKERRR LVLMVRETPL NLAHLDNMXR VTEMGGVVFP PVPAMYRKPQ


 


201
TADDIVAHSV AHALSLFGID TPDSAEWQGM AD*






m308/a308 95.7% identity in 231 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1283>:










g308-1.seq




1
ATGTTAAATC GGGTATTTTA TCGGATATTG GGTGTTGCCG ACAATTTGTA


 


51
TCCGTGTTTA TCGGATTTCT GTTTTTTCAC TATAATAGCC GGTTTGCCGT


 


101
TGCAGGCGGT TTTATGGGAA AGGCGGATGA TGGTACGGCG TTTGATAATC


 


151
GGCATCAGCG GGGCGAGCGG TTTCCAATAC GGCGTGAAGG CTTTGGAACT


 


201
TTTGCGCGCG CAAGATGTCG AAACGCACCT TGTGGTATCG AAAGGCGCGG


 


251
AGATGGCGCG CGCTTCGGAA ACGGATTATA CGAAAGACGA AGTATATGCC


 


301
TTGGCTGATT TCGTCCATCC GATCGGCAAT ATCGGGGCGT GCATTGCCAG


 


351
CGGTACGTTT AAAACGGACG GGATGCTGGT CGCACCCTGT TCGATGCGGA


 


401
CGCTTGCCTC TGTCGCGCAC GGCTTCGGCG ACAACCTCTT GACGCGTGCG


 


451
GCGGATGTGG TTTTGAAGGA AAGGCGGCGG CTGGTGCTGA TGGTGCGCGA


 


501
AACGCCGCTG AACCTTGCCC ATTTGGACAA TATGAAGCGG GTAACGGAAA


 


551
TGGGCGGCGT GGTGTTTCCC CCTGTTCCTG CGATGTACCG CAAGCCGCAG


 


601
ACGGCGGACG ACATAGTGGC GCACAGTATC GCACACACGC TGTCGCTGTT


 


651
CGGAATCGAT ACGCCGGATT TGGCGGAATG GCAGGGAATG GCGGATTAA






This corresponds to the amino acid sequence <SEQ ID 1284; ORF 308-1.ng>:










g308-1.pep




1
MLNRVFYRIL GVADNLYPCL SDFCFFTIIA GLPLQAVLWE RRMMVRRLII


 


51
GISGASGFQY GVKALELLRA QDVETHLVVS KGAEMARASE TDYTKDEVYA


 


101
LADFVHPIGN IGACIASGTF KTDGMLVAPC SMRTLASVAH GFGDNLLTRA


 


151
ADVVLKERRR LVLMVRETPL NLAHLDNMKR VTEMGGVVFP PVPAMYRKPQ


 


201
TADDIVAHSI AHTLSLFGID TPDLAEWQGM AD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1285>:










m308-1.seq




1
ATGTTAAATC GGGTATTTTA TCGGATATTG GGTGTTGCCG ACAATTTGTA


 


51
TCCGCGTTTA TCGGATTTCT GTTTTTTCAC TATAATAGCC GGTTTGCCGT


 


101
TGCAGGCGGT TTTATGGGAA AGGCGGATGA TGGTACGGCG TTTGATAATC


 


151
GGCATCAGCG GGGCGAGCGG TTTCCAATAC GGCGTGAAGG CTTTGGAACT


 


201
TTTGCGCGCG CAAGATGTCG AAACGCACCT TGTGGTATCG AAAGGTGCGG


 


251
AGATGGCGCG CGCTTCGGAA ACGGCTTATG CGAGAGACGA GGTATATGCC


 


301
TTGGCGGACT TCGTGCATCC GATCGGCAAT ATCGGGGCGT GCATTGCCAG


 


351
CGGTACGTTT AAAACGGATG GGATGCTGGT CGCCCCCTGT TCGATGCGGA


 


401
CGCTTGCCTC TGTCGCGCAC GGCTTCGGCG ACAATCTGCT GACGCGTGCG


 


451
GCGGATGTGG TTTTGAAGGA AAGGCGGCGG CTGGTGCTGA TGGTGCGCGA


 


501
AACGCCGCTG AACCTTGCCC ATTTGGACAA TATGAAGCGG GTAACGGAAA


 


551
TGGGCGGCGT GGTGTTTCCC CCTGTTCCTG CGATGTACCG CAAACCGCAG


 


601
ACGGCGGACG ACATAGTGGC GCACAGTGTT GCACACGCTT TGTCGCTGTT


 


651
CGGAATCGAT ACGCCGGATT CGGCGGAATG GCAGGGAATG GCGGATTAA






This corresponds to the amino acid sequence <SEQ ID 1286; ORF 308-1>:










m308-1.pep




1
MLNRVFYRIL GVADNLYPRL SDFCFFTIIA GLPLQAVLWE RRMMVRRLII


 


51
GISGASGFQY GVKALELLRA QDVETHLVVS KGAEMARASE TAYARDEVYA


 


101
LADFVHPIGN IGACIASGTF KTDGMLVAPC SMRTLASVAH GFGDNLLTRA


 


151
ADVVLKERRR LVLMVRETPL NLAHLDNMKR VTEMGGVVFP PVPAMYRKPQ


 


201
TADDIVAHSV AHALSLFGID TPDSAEWQGM AD*






m308-1/g308-1 97.0% identity in 232 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1287>:










a308-1.seq




1
ATGTTAAATC GGATATTTTA TCGGATATTG GGTGTTGCCG ACAATTTGTA


 


51
TCCGTATTTA TCGGATTTCT GTTTTTTCAC TATAATAGCC GGTTTGCCGT


 


101
TGCAGGCGGT TTTATGGGAA AGGCGGATGA TGGTACGGCG TTTGATAATC


 


151
GGCATCAGTG GGGCGAGCGG TTTCCAATAC GGCGTGAAGG CTTTGGANCT


 


201
TTTACGCGCG CAAGATATCG AAACGCACCT TGTGGTATCG AAAGGTGCGG


 


251
AGATGGCGCG CGCTTCGGAA ACGGNTTATG CGAGAGACGA NGTATATGCC


 


301
TTGGCGGACT TNGTGCATCC GATCGGCAAT ATCGGGGCGT GCATTGCCAG


 


351
CGGTACGTTT AAAACGGACG GGATGCTGGT CGCCCCCTGT TCGATGCGGA


 


401
CGCTTGCCTC GGTCGTGCAC GGCTTCGGCG ACAACCTCTT GACGCGTGCG


 


451
GCGGATGTGG TTTTGAAGGA AAGGCGGCGG CTGGTGCTGA TGGTGCGCGA


 


501
AACGCCGCTG AACCTTGCCC ATTTGGACAA TATGAANCGG GTAACGGAAA


 


551
TGGGCGGCGT GGTGTTTCCC CCTGTTCCTG CGATGTACCG CAAACCGCAG


 


601
ACGGCGGACG ACATAGTGGC GCACAGTGTT GCACACGCTT TGTCGCTGTT


 


651
CGGAATCGAT ACGCCGGATT CGGCGGAATG GCAGGGAATG GCGGATTAA






This corresponds to the amino acid sequence <SEQ ID 1288; ORF 308-1.a>:










a308-1.pep




1
MLNRIFYRIL GVADNLYPYL SDFCFFTIIA GLPLQAVLWE RRMMVRRLII


 


51
GISGASGFQY GVKALXLLRA QDIETHLVVS KGAEMARASE TXYARDXVYA


 


101
LADXVHPIGN IGACIASGTF KTDGMLVAPC SMRTLASVVH GFGDNLLTRA


 


151
ADVVLKERRR LVLMVRETPL NLAHLDNMXR VTEMGGVVFP PVPAMYRKPQ


 


201
TADDIVAHSV AHALSLFGID TPDSAEWQGM AD*






a308-1/m308-1 96.1% identity in 232 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1289>:










g311.seq




1
atgttcagtt tcggctgggc gtttgaccgc ccgcagtatg agttgggttc


 


51
gctgtcgcct gttgcggcac ttgcgtgccg gcgcgctttg gggtgtttgg


 


101
gtttggaaac gcaaatcaag tggccaaacg atttggtcgt cggacgcgac


 


151
aaattgggcg gcattctgat tgaaacagtc agggcgggcg gtaaaacggt


 


201
tgccgtggtc ggtatcggca tcaatttcgt gctgcccaag gaagtggaaa


 


251
acgccgcttc cgtgcagtcg ctgtttcaga cggcatcgcg gcggggcaat


 


301
gccgatgccg ccgtattgct ggaaacattg cttgcggaac tgggcgcggt


 


351
gttggaacaa tatgcggaag aagggttcgc gccattttta aatgagtatg


 


401
aaacggccaa ccgcgaccac ggcaaggcgg tattgctgtt gcgcgacggc


 


451
gaaaccgtgt gcgaaggcac ggttaaaggc gtggacggac gaggcgttct


 


501
gcacttggaa acggcagaag gcgaacagac ggtcgtcagc ggcgaaatca


 


551
gcctgcggcc cgacaacagg tcggtttccg tgccgaagcg gccggattcg


 


601
gaacgttttt tgctgttgga aggcgggaac agccggctca agtgggcgtg


 


651
ggtggaaaac ggcacgttcg caaccgtggg cagcgcgccg taccgcgatt


 


701
tgtcgccttt gggcgcggag tgggcggaaa aggcggatgg aaatgtccgc


 


751
atcgtcggtt gcgccgtgtg cggagaatcc aaaaaggcac aagtgaagga


 


801
acagctcgcc cgaaaaatcg agtggctgcc gtcttccgca caggctttgg


 


851
gcatacgcaa ccactaccgc caccccgaag aacacggttc cgaccgttgg


 


901
ttcaacgcct tgggcagccg ccgcttcagc cgcaacgcct gcgtcgtcgt


 


951
cagttgcggc acggcggtaa cggttgacgc gctcaccgat gacggacatt


 


1001
atctcggcgg aaccatcatg cccggcttcc acctgatgaa agaatcgctc


 


1051
gccgtccgaa ccgccaacct caaccgcccc gccggcaaac gttacccttt


 


1101
cccgaccaca acgggcaacg ccgtcgcaag cggcatgatg gacgcggttt


 


1151
gcggctcgat aatgatgatg cacggccgtt tgaaagaaaa aaacggcgcg


 


1201
ggcaagcctg tcgatgtcat cattaccggc ggcggcgcgg cgaaagtcgc


 


1251
cgaagccctg ccgcctgcat ttttggcgga aaataccgtg cgcgtggcgg


 


1301
acaacctcgt catccacggg ctgctgaacc tgattgccgc cgaaggcggg


 


1351
gaatcggaac acgcttaa






This corresponds to the amino acid sequence <SEQ ID 1290; ORF 311.ng>:










g311.pep




1
MFSFGWAFDR PQYELGSLSP VAALACRRAL GCLGLETQIK WPNDLVVGRD


 


51
KLGGILIETV RAGGKTVAVV GIGINFVLPK EVENAASVQS LFQTASRRGN


 


101
ADAAVLLETL LAELGAVLEQ YAEEGFAPFL NEYETANRDH GKAVLLLRDG


 


151
ETVCEGTVKG VDGRGVLHLE TAEGEQTVVS GEISLRPDNR SVSVPKRPDS


 


201
ERFLLLEGGN SRLKWAWVEN GTFATVGSAP YRDLSPLGAE WAEKADGNVR


 


251
IVGCAVCGES KKAQVKEQLA RKIEWLPSSA QALGIRNHYR HPEEHGSDRW


 


301
FNALGSRRFS RNACVVVSCG TAVTVDALTD DGHYLGGTIM PGFHLMKESL


 


351
AVRTANLNRP AGKRYPFPTT TGNAVASGMM DAVCGSIMMM HGRLKEKNGA


 


401
GKPVDVIITG GGAAKVAEAL PPAFLAENTV RVADNLVIHG LLNLIAAEGG


 


451
ESEHA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1291>:









m311.seq (partial)










1
ATGTTCAGTT TTGGCTGGGT GTTTGACCGG CCGCAGTATG AGTTGGGTTC



 


51
GCTGTCGCCT GTTGCGGCAG TGGCGTGTCG GCGCGCCTTG TCGCGTTTAG


 


101
GTTTGGATGT GCArATTAAG TGGCCCAATG ATTTGGTTGT CGGACGCGAC


 


151
AAATTGGGCG GCATTCTGAT TGAAACGGTC AGGACGGGCG GCAAAACGGT


 


201
TGCCGTGGTC GGTATCGGCA TCAATTTTGT CCTGCCCAAn GAAGTAGAAA


 


251
ATGCCGCTTC CGTGCAATCG CTGTTTCAGA CGGCATCGCG GCGGGGCAAT


 


301
GCCGATGCCG CCGTGCTGCT nnnnnnnnnn nnnnnnnnnn nnnnGGAAAT


 


351
CAGCCTGCGG TCCGACnACA GGCCGGTTTC CGTGnCGAAG CGGCGGGATT


 


401
CGGAACGTTT TCTGCTGTTG GACGGCGGCA ACAGCCGGCT CAAGTGGgCG


 


451
TGGGTGGAAA ACGGCACGTT CGCAACCGTC GGTAGCGCGC CGTACCgCGA


 


501
TTTGTCGCCT TTGGGCGCGG AGTGGGCGGA AAAGGCGGAT GGAAATGTCC


 


551
GCATCGTCGG TTGCGCTGTG TGCGGAGAAT TCAAAAAGGC ACAAGTGCAG


 


601
GAACAGCTCG CCCGAAAAAT CGAGTGGCTG CCGTCTTCCG CACAGGCTTT


 


651
GTTTGGCATA CGCAACCACT ACCGCCACCC CGAAGAACAC GGTTCCGACC


 


701
GCTGGTTCAA CGCCTTGGGC AGCCGCCGCT TCAGCCGCAA CGCyTGCGTC


 


751
GTCGTCAGTT GCGGCACGGC GGTAACGGTT GACGCGCTCA CCGATGACGG


 


801
ACATTATCTC GGrgGAACCA TCATGCCCGG TTTCCACCTG ATGAAAGAAT


 


851
CGCTCGCCGT CCGAACCGCC AACCTCAACC GGCACGCCGG TAAGCGTTAT


 


901
CCTTTCCCGA CCACAACGGG CAATGCCGTC GCCAGCGGCA TGATGGATGC


 


951
GGTTTGCGGC TCGGTTATGA TGATGCACGG GCGTTTGAAA GAAAAAACCG


 


1001
GGGCGGGCAA GCCTGTCGAT GTCATCATTA CCGGCGGCGG CGCGGCAAAA


 


1051
GTTGCCGAAG CCCTGCCGCC TGCATTTTTG GCGGAAAATA CCGTGCGCGT


 


1101
GGCGGACAAC CTCGTCATTT ACGGGTTGTT GAACATGATT GCCGCCGAAG


 


1151
GCAGGGAATA TGAACAT....






This corresponds to the amino acid sequence <SEQ ID 1292; ORF 311>:









m311.pep (partial)










1
MFSFGWVFDR PQYELGSLSP VAAVACRRAL SRLGLDVQIK WPNDLVVGRD



 


51
KLGGILIETV RTGGKTVAVV GIGINFVLPX EVENAASVQS LFQTASRRGN


 


101
ADAAVLLXXX XXXXXEISLR SDXRPVSVXK RRDSERFLLL DGGNSRLKWA


 


151
WVENGTFATV GSAPYRDLSP LGAEWAEKAD GNVRIVGCAV CGEFKKAQVQ


 


201
EQLARKIEWL PSSAQALFGI RNHYRHPEEH GSDRWFNALG SRRFSRNACV


 


251
VVSCGTAVTV DALTDDGHYL GGTIMPGFHL MKESLAVRTA NLNRHAGKRY


 


301
PFPTTTGNAV ASGMMDAVCG SVMMMHGRLK EKTGAGKPVD VIITGGGAAK


 


351
VAEALPPAFL AENTVRVADN LVIYGLLNMI AAEGREYEH....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 311 shows 78.5% identity over a 455 aa overlap with a predicted ORF (ORF 311.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitides <SEQ ID 1293>:










a311.seq




1
ATGTTCAGTT TTGGCTGGGT GTTTGACCGG CCGCAGTATG AGTTGGGTTC


 


51
GCTGTCGCCT GTTGCGGCAG TGGCGTGCCG GCGCGCCTTG TCGCGTTTGG


 


101
GTTTGAAAAC GCAAATCAAG TGGCCAAACG ATTTGGTCGT CGGACGCGAC


 


151
AAATTGGGCG GCATTCTGAT TGAAACGGTC AGGACGGGCG GCAAAACGGT


 


201
TGCCGTGGTC GGTATCGGCA TCAATTTCGT GCTGCCCAAG GAAGTGGAAA


 


251
ACGCCGCTTC CGTGCAATCG CTGTTTCAGA CGGCATCGCG GCGGGGAAAT


 


301
GCCGATGCCG CCGTGTTGCT GGAAACGCTG TTGGCGGAAC TTGATGCGGT


 


351
GTTGTTGCAA TATGCGCGGG ACGGATTTGC GCCTTTTGTG GCGGAATATC


 


401
AGGCTGCCAA CCGCGACCAC GGCAAGGCGG TATTGCTGTT GCGCGACGGC


 


451
GAAACCGTGT TCGAAGGCAC GGTTAAAGGC GTGGACGGAC AAGGCGTTCT


 


501
GCACTTGGAA ACGGCAGAGG GCAAACAGAC GGTCGTCAGC GGCGAAATCA


 


551
GCCTGCGGTC CGACGACAGG CCGGTTTCCG TGCCGAAGCG GCGGGATTCG


 


601
GAACGTTTTC TGCTGTTGGA CGGCGGCAAC AGCCGGCTCA AGTGGGCGTG


 


651
GGTGGAAAAC GGCACGTTCG CAACCGTCGG TAGCGCGCCG TACCGCGATT


 


701
TGTCGCCTTT GGGCGCGGAG TGGGCGGAAA AGGTGGATGG AAATGTCCGC


 


751
ATCGTCGGTT GCGCCGTGTG CGGAGAATTC AAAAAGGCAC AAGTGCAGGA


 


801
ACAGCTCGCC CGAAAAATCG AGTGGCTGCC GTCTTCCGCA CAGGCTTTGG


 


851
GCATACGCAA CCACTACCGC CACCCCGAAG AACACGGTTC CGACCGCTGG


 


901
TTCAACGCCT TGGGCAGCCG CCGCTTCAGC CGCAACGCCT GCGTCGTCGT


 


951
CAGTTGCGGC ACGGCGGTAA CGGTTGACGC GCTCACCGAT GACGGACATT


 


1001
ATCTCGGGGG AACCATCATG CCCGGTTTCC ACCTGATGAA AGAATCGCTC


 


1051
GCCGTCCGAA CCGCCAACCT CAACCGGCAC GCCGGTAAGC GTTATCCTTT


 


1101
CCCGACCACA ACGGGCAATG CCGTCGCCAG CGGCATGATG GATGCGGTTT


 


1151
GCGGCTCGGT TATGATGATG CACGGGCGTT TGAAAGAAAA AACCGGGGCG


 


1201
GGCAAGCCTG TCGATGTCAT CATTACCGGC GGCGGCGCGG CAAAAGTTGC


 


1251
CGAAGCCCTG CCGCCTGCAT TTTTGGCGGA AAATACCGTG CGCGTGGCGG


 


1301
ACAACCTCGT CATTCACGGG CTGCTGAACC TGATTGCCGC CGAAGGCGGG


 


1351
GAATCGGAAC ATACTTAA






This corresponds to the amino acid sequence <SEQ ID 1294; ORF 311.a>:










a311.pep




1
MFSFGWVFDR PQYELGSLSP VAAVACRRAL SRLGLKTQIK WPNDLVVGRD


 


51
KLGGILIETV RTGGKTVAVV GIGINFVLPK EVENAASVQS LFQTASRRGN


 


101
ADAAVLLETL LAELDAVLLQ YARDGFAPFV AEYQAANRDH GKAVLLLRDG


 


151
ETVFEGTVKG VDGQGVLHLE TAEGKQTVVS GEISLRSDDR PVSVPKRRDS


 


201
ERFLLLDGGN SRLKWAWVEN GTFATVGSAP YRDLSPLGAE WAEKVDGNVR


 


251
IVGCAVCGEF KKAQVQEQLA RKIEWLPSSA QALGIRNHYR HPEEHGSDRW


 


301
FNALGSRRFS RNACVVVSCG TAVTVDALTD DGHYLGGTIM PGFHLMKESL


 


351
AVRTANLNRH AGKRYPFPTT TGNAVASGMM DAVCGSVMMM HGRLKEKTGA


 


401
GKPVDVIITG GGAAKVAEAL PPAFLAENTV RVADNLVIHG LLNLIAAEGG


 


451
ESEHT*






m311/a311 81.3% identity in 455 an overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1295>:










g311-1.seq




1
ATGACGGTTT TGAAGCCTTC GCATTGGCGG GTGTTGGCGG AGCTTGCCGA


 


51
CGGTTTGCCG CAACACGTAT CGCAATTGGC GCGTGAGGCG GACATGAAGC


 


101
CGCAGCAGCT CAACGGTTTT TGGCAGCAGA TGCCGGCGCA TATACGCGGG


 


151
CTGTTGCGCC AACACGACGG CTATTGGCGG CTGGTGCGCC CCTTGGCGGT


 


201
TTTCGATGCC GAAGGTTTGC GCGATCTGGG GGAAAGGTCG GGTTTTCAGA


 


251
CGGCATTGAA GCACGAGTGC GCGTCCAGCA ACGACGAGAT ACTGGAATTG


 


301
GCGCGGATTG CGCCGGACAA GGCGCACAAA ACCATATGCG TGACCCACCT


 


351
GCAAAGTAAG GGCAGGGGGC GGCAGGGGCG GAAGTGGTCG CACCGTTTGG


 


401
GCGAGTGCCT GATGTTCAGT TTCGGCTGGG CGTTTGACCG GCCGCAGTAT


 


451
GAGTTGGGTT CGCTGTCGCC TGTTGCGGCA CTTGCGTGCC GGCGCGCTTT


 


501
GGGGTGTTTG GGTTTGGAAA CGCAAATCAA GTGGCCAAAC GATTTGGTCG


 


551
TCGGACGCGA CAAATTGGGC GGCATTCTGA TTGAAACAGT CAGGGCGGGC


 


601
GGTAAAACGG TTGCCGTGGT CGGTATCGGC ATCAATTTCG TGCTGCCCAA


 


651
GGAAGTGGAA AACGCCGCTT CCGTGCAGTC GCTGTTTCAG ACGGCATCGC


 


701
GGCGGGGCAA TGCCGATGCC GCCGTATTGC TGGAAACATT GCTTGCGGAA


 


751
CTGGGCGCGG TGTTGGAACA ATATGCGGAA GAAGGGTTCG CGCCATTTTT


 


801
AAATGAGTAT GAAACGGCCA ACCGCGACCA CGGCAAGGCG GTATTGCTGT


 


851
TGCGCGACGG CGAAACCGTG TGCGAAGGCA CGGTTAAAGG CGTGGACGGA


 


901
CGAGGCGTTC TGCACTTGGA AACGGCAGaa ggCGAACAGa cggtcGtcag


 


951
cggcGaaaTC AGccTGCGGc CCGacaacag gtcggtttcc GTgccgaagc


 


1001
gGccggatTC GgaacgttTT tTGCTgttgg aaggcgggaa cagccggctc


 


1051
aAGTGGgcgt gGGTggAAAA Cggcacgttc gcaaccgtgg gcAGCGCgCC


 


1101
gtaCCGCGAT TTGTCGCCTT TGGGCGCGGA GTGGGCGGAA AAGGCGGATG


 


1151
GAAATGTCCG CATCGTCGGT TGCGCCGTGT GCGGAGAATC CAAAAAGGCA


 


1201
CAAGTGAAGG AACAGCTCGC CCGAAAAATC GAGTGGCTGC CGTCTTCCGC


 


1251
ACAGGCTTTG GGCATACGCA ACCACTACCG CCACCCCGAA GAACACGGTT


 


1301
CCGACCGTTG GTTCAACGCC TTGGGCAGCC GCCGCTTCAG CCGCAACGCC


 


1351
TGCGTCGTCG TCAGTTGCGG CACGGCGGTA ACGGTTGACG CGCTCACCGA


 


1401
TGACGGACAT TATCTCGGCG GAACCATCAT GCCCGGCTTC CACCTGATGA


 


1451
AAGAATCGCT CGCCGTCCGA ACCGCCAACC TCAACCGCCC CGCCGGCAAA


 


1501
CGTTACCCTT TCCCGACCAC AACGGGCAAC GCCGTCGCAA GCGGCATGAT


 


1551
GGACGCGGTT TGCGGCTCGA TAATGATGAT GCACGGCCGT TTGAAAGAAA


 


1601
AAAACGGCGC GGGCAAGCCT GTCGATGTCA TCATTACCGG CGGCGGCGCG


 


1651
GCGAAAGTCG CCGAAGCCCT GCCGCCTGCA TTTTTGGCGG AAAATACCGT


 


1701
GCGCGTGGCG GACAACCTCG TCATCCACGG GCTGCTGAAC CTGATTGCCG


 


1751
CCGAAGGCGG GGAATCGGAA CACGCTTAA






This corresponds to the amino acid sequence <SEQ ID 1294; ORF 311-1.ng>:










g311-1.pep




1
MTVLKPSHWR VLAELADGLP QHVSQLAREA DMKPQQLNGF WQQMPAHIRG


 


51
LLRQHDGYWR LVRPLAVFDA EGLRDLGERS GFQTALKHEC ASSNDEILEL


 


101
ARIAPDKAHK TICVTHLQSK GRGRQGRKWS HRLGECLMFS FGWAFDRPQY


 


151
ELGSLSPVAA LACRRALGCL GLETQIKWPN DLVVGRDKLG GILIETVRAG


 


201
GKTVAVVGIG INFVLPKEVE NAASVQSLFQ TASRRGNADA AVLLETLLAE


 


251
LGAVLEQYAE EGFAPFLNEY ETANRDHGKA VLLLRDGETV CEGTVKGVDG


 


301
RGVLHLETAE GEQTVVSGEI SLRPDNRSVS VPKRPDSERF LLLEGGNSRL


 


351
KWAWVENGTF ATVGSAPYRD LSPLGAEWAE KADGNVRIVG CAVCGESKKA


 


401
QVKEQLARKI EWLPSSAQAL GIRNHYRHPE EHGSDRWFNA LGSRRFSRNA


 


451
CVVVSCGTAV TVDALTDDGH YLGGTIMPGF HLMKESLAVR TANLNRPAGK


 


501
RYPFPTTTGN AVASGMMDAV CGSIMMMHGR LKEKNGAGKP VDVIITGGGA


 


551
AKVAEALPPA FLAENTVRVA DNLVIHGLLN LIAAEGGESE HA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1297>:










m311-1.seq




1
ATGACGGTTT TGAAGCTTTC GCACTGGCGG GTGTTGGCGG AGCTTGCCGA


 


51
CGGTTTGCCG CAACACGTCT CGCAACTGGC GCGTATGGCG GATATGAAGC


 


101
CGCAGCAGCT CAACGGTTTT TGGCAGCAGA TGCCGGCGCA CATACGCGGG


 


151
CTGTTGCGCC AACACGACGG CTATTGGCGG CTGGTGCGCC CATTGGCGGT


 


201
TTTCGATGCC GAAGGTTTGC GCGAGCTGGG GGAAAGGTCG GGTTTTCAGA


 


251
CGGCATTGAA GCACGAGTGC GCGTCCAGCA ACGACGAGAT ACTGGAATTG


 


301
GCGCGGATTG CGCCGGACAA GGCGCACAAA ACCATATGCG TGACCCACCT


 


351
GCAAAGTAAG GGCAGGGGGC GGCAGGGGCG GAAGTGGTCG CACCGTTTGG


 


401
GCGAGTGTCT GATGTTCAGT TTTGGCTGGG TGTTTGACCG GCCGCAGTAT


 


451
GAGTTGGGTT CGCTGTCGCC TGTTGCGGCA GTGGCGTGTC GGCGCGCCTT


 


501
GTCGCGTTTA GGTTTGGATG TGCAGATTAA GTGGCCCAAT GATTTGGTTG


 


551
TCGGACGCGA CAAATTGGGC GGCATTCTGA TTGAAACGGT CAGGACGGGC


 


601
GGCAAAACGG TTGCCGTGGT CGGTATCGGC ATCAATTTTG TCCTGCCCAA


 


651
GGAAGTAGAA AATGCCGCTT CCGTGCAATC GCTGTTTCAG ACGGCATCGC


 


701
GGCGGGGCAA TGCCGATGCC GCCGTGCTGC TGGAAACGCT GTTGGTGGAA


 


751
CTGGACGCGG TGTTGTTGCA ATATGCGCGG GACGGATTTG CGCCTTTTGT


 


801
GGCGGAATAT CAGGCTGCCA ACCGCGACCA CGGCAAGGCG GTATTGCTGT


 


851
TGCGCGACGG CGAAACCGTG TTCGAAGGCA CGGTTAAAGG CGTGGACGGA


 


901
CAAGGCGTTT TGCACTTGGA AACGGCAGAG GGCAAACAGA CGGTCGTCAG


 


951
CGGCGAAATC AGCCTGCGGT CCGACGACAG GCCGGTTTCC GTGCCGAAGC


 


1001
GGCGGGATTC GGAACGTTTT CTGCTGTTGG ACGGCGGCAA CAGCCGGCTC


 


1051
AAGTGGGCGT GGGTGGAAAA CGGCACGTTC GCAACCGTCG GTAGCGCGCC


 


1101
GTACCGCGAT TTGTCGCCTT TGGGCGCGGA GTGGGCGGAA AAGGCGGATG


 


1151
GAAATGTCCG CATCGTCGGT TGCGCTGTGT GCGGAGAATT CAAAAAGGCA


 


1201
CAAGTGCAGG AACAGCTCGC CCGAAAAATC GAGTGGCTGC CGTCTTCCGC


 


1251
ACAGGCTTTG GGCATACGCA ACCACTACCG CCACCCCGAA GAACACGGTT


 


1301
CCGACCGCTG GTTCAACGCC TTGGGCAGCC GCCGCTTCAG CCGCAACGCC


 


1351
TGCGTCGTCG TCAGTTGCGG CACGGCGGTA ACGGTTGACG CGCTCACCGA


 


1401
TGACGGACAT TATCTCGGGG GAACCATCAT GCCCGGTTTC CACCTGATGA


 


1451
AAGAATCGCT CGCCGTCCGA ACCGCCAACC TCAACCGGCA CGCCGGTAAG


 


1501
CGTTATCCTT TCCCGACCAC AACGGGCAAT GCCGTCGCCA GCGGCATGAT


 


1551
GGATGCGGTT TGCGGCTCGG TTATGATGAT GCACGGGCGT TTGAAAGAAA


 


1601
AAACCGGGGC GGGCAAGCCT GTCGATGTCA TCATTACCGG CGGCGGCGCG


 


1651
GCAAAAGTTG CCGAAGCCCT GCCGCCTGCA TTTTTGGCGG AAAATACCGT


 


1701
GCGCGTGGCG GACAACCTCG TCATTTACGG GTTGTTGAAC ATGATTGCCG


 


1751
CCGAAGGCAG GGAATATGAA CATATTTAA






This corresponds to the amino acid sequence <SEQ ID 1298; ORF 311-1>:










m311-1.pep




1
MTVLKLSHWR VLAELADGLP QHVSQLARMA DMKPQQLNGF WQQMPAHIRG


 


51
LLRQHDGYWR LVRPLAVFDA EGLRELGERS GFQTALKHEC ASSNDEILEL


 


101
ARIAPDKAHK TICVTHLQSK GRGRQGRKWS HRLGECLMFS FGWVFDRPQY


 


151
ELGSLSPVAA VACRRALSRL GLDVQIKWPN DLVVGRDKLG GILIETVRTG


 


201
GKTVAVVGIG INFVLPKEVE NAASVQSLFQ TASRRGNADA AVLLETLLVE


 


251
LDAVLLQYAR DGFAPFVAEY QAANRDHGKA VLLLRDGETV FEGTVKGVDG


 


301
QGVLHLETAE GKQTVVSGEI SLRSDDRPVS VPKRRDSERF LLLDGGNSRL


 


351
KWAWVENGTF ATVGSAPYRD LSPLGAEWAE KADGNVRIVG CAVCGEFKKA


 


401
QVQEQLARKI EWLPSSAQAL GIRNHYRHPE EHGSDRWFNA LGSRRFSRNA


 


451
CVVVSCGTAV TVDALTDDGH YLGGTIMPGF HLMKESLAVR TANLNRHAGK


 


501
RYPFPTTTGN AVASGMMDAV CGSVMMMHGR LKEKTGAGKP VDVIITGGGA


 


551
AKVAEALPPA FLAENTVRVA DNLVIYGLLN MIAAEGREYE HI*






m311-1/g311-1 93.9% identity in 591 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1299>:










a311-1.seq




1
ATGACGGTTT TGAAGCCTTC GCACTGGCGG GTGTTGGCGG AGCTTGCCGA


 


51
CGGTTTGCCG CAACACGTCT CGCAACTGGC GCGTATGGCG GATATGAAGC


 


101
CGCAGCAGCT CAACGGTTTT TGGCAGCAGA TGCCGGCGCA CATACGCGGG


 


151
CTGTTGCGCC AACACGACGG CTATTGGCGG CTGGTGCGCC CATTGGCGGT


 


201
TTTCGATGCC GAAGGTTTGC GCGAGCTGGG GGAAAGGTCG GGTTTTCAGA


 


251
CGGCATTGAA GCACGAGTGC GCGTCCAGCA ACGACGAGAT ACTGGAATTG


 


301
GCGCGGATTG CGCCGGACAA GGCGCACAAA ACCATATGTG TGACCCACCT


 


351
GCAAAGTAAG GGCAGGGGGC GGCAGGGGCG GAAGTGGTCG CACCGTTTGG


 


401
GCGAGTGTCT GATGTTCAGT TTTGGCTGGG TGTTTGACCG GCCGCAGTAT


 


451
GAGTTGGGTT CGCTGTCGCC TGTTGCGGCA GTGGCGTGCC GGCGCGCCTT


 


501
GTCGCGTTTG GGTTTGAAAA CGCAAATCAA GTGGCCAAAC GATTTGGTCG


 


551
TCGGACGCGA CAAATTGGGC GGCATTCTGA TTGAAACGGT CAGGACGGGC


 


601
GGCAAAACGG TTGCCGTGGT CGGTATCGGC ATCAATTTCG TGCTGCCCAA


 


651
GGAAGTGGAA AACGCCGCTT CCGTGCAATC GCTGTTTCAG ACGGCATCGC


 


701
GGCGGGGAAA TGCCGATGCC GCCGTGTTGC TGGAAACGCT GTTGGCGGAA


 


751
CTTGATGCGG TGTTGTTGCA ATATGCGCGG GACGGATTTG CGCCTTTTGT


 


801
GGCGGAATAT CAGGCTGCCA ACCGCGACCA CGGCAAGGCG GTATTGCTGT


 


851
TGCGCGACGG CGAAACCGTG TTCGAAGGCA CGGTTAAAGG CGTGGACGGA


 


901
CAAGGCGTTC TGCACTTGGA AACGGCAGAG GGCAAACAGA CGGTCGTCAG


 


951
CGGCGAAATC AGCCTGCGGT CCGACGACAG GCCGGTTTCC GTGCCGAAGC


 


1001
GGCGGGATTC GGAACGTTTT CTGCTGTTGG ACGGCGGCAA CAGCCGGCTC


 


1051
AAGTGGGCGT GGGTGGAAAA CGGCACGTTC GCAACCGTCG GTAGCGCGCC


 


1101
GTACCGCGAT TTGTCGCCTT TGGGCGCGGA GTGGGCGGAA AAGGTGGATG


 


1151
GAAATGTCCG CATCGTCGGT TGCGCCGTGT GCGGAGAATT CAAAAAGGCA


 


1201
CAAGTGCAGG AACAGCTCGC CCGAAAAATC GAGTGGCTGC CGTCTTCCGC


 


1251
ACAGGCTTTG GGCATACGCA ACCACTACCG CCACCCCGAA GAACACGGTT


 


1301
CCGACCGCTG GTTCAACGCC TTGGGCAGCC GCCGCTTCAG CCGCAACGCC


 


1351
TGCGTCGTCG TCAGTTGCGG CACGGCGGTA ACGGTTGACG CGCTCACCGA


 


1401
TGACGGACAT TATCTCGGGG GAACCATCAT GCCCGGTTTC CACCTGATGA


 


1451
AAGAATCGCT CGCCGTCCGA ACCGCCAACC TCAACCGGCA CGCCGGTAAG


 


1501
CGTTATCCTT TCCCGACCAC AACGGGCAAT GCCGTCGCCA GCGGCATGAT


 


1551
GGATGCGGTT TGCGGCTCGG TTATGATGAT GCACGGGCGT TTGAAAGAAA


 


1601
AAACCGGGGC GGGCAAGCCT GTCGATGTCA TCATTACCGG CGGCGGCGCG


 


1651
GCAAAAGTTG CCGAAGCCCT GCCGCCTGCA TTTTTGGCGG AAAATACCGT


 


1701
GCGCGTGGCG GACAACCTCG TCATTCACGG GCTGCTGAAC CTGATTGCCG


 


1751
CCGAAGGCGG GGAATCGGAA CATACTTAA






This corresponds to the amino acid sequence <SEQ ID 1300; ORF 311-1.a>:










a311-1.pep




1
MTVLKPSHWR VLAELADGLP QHVSQLARMA DMKPQQLNGF WQQMPAHIRG


 


51
LLRQHDGYWR LVRPLAVFDA EGLRELGERS GFQTALKHEC ASSNDEILEL


 


101
ARIAPDKAHK TICVTHLQSK GRGRQGRKWS HRLGECLMFS FGWVFDRPQY


 


151
ELGSLSPVAA VACRRALSRL GLKTQIKWPN DLVVGRDKLG GILIETVRTG


 


201
GKTVAVVGIG INFVLPKEVE NAASVQSLFQ TASRRGNADA AVLLETLLAE


 


251
LDAVLLQYAR DGFAPFVAEY QAANRDHGKA VLLLRDGETV FEGTVKGVDG


 


301
QGVLHLETAE GKQTVVSGEI SLRSDDRPVS VPKRRDSERF LLLDGGNSRL


 


351
KWAWVENGTF ATVGSAPYRD LSPLGAEWAE KVDGNVRIVG CAVCGEFKKA


 


401
QVQEQLARKI EWLPSSAQAL GIRNHYRHPE EHGSDRWFNA LGSRRFSRNA


 


451
CVVVSCGTAV TVDALTDDGH YLGGTIMPGF HLMKESLAVR TANLNRHAGK


 


501
RYPFPTTTGN AVASGMMDAV CGSVMMMHGR LKEKTGAGKP VDVIITGGGA


 


551
AKVAEALPPA FLAENTVRVA DNLVIHGLLN LIAAEGGESE HT*






a311-1/m311-1 98.5% identity in 591 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1301>:










g312.seq




1
atgaGtatCc aatCcGgcga AATTTtagaa accgtCAAAA TGGTTGCCGA


 


51
ccggaATttt gAtgtccgCA CCATTAccat cggcaTTgaT ttgcacgact


 


101
gcatcagcac cgacatcgac gtgttaAACC AAAACATtta caaCAaaaTc


 


151
accacggtcg gcaaagactT GGTGGCAacg Gcgaaacacc tTTccgcCAA


 


201
ATACGGCGTG CCGATTGTGA ATCAGCGCAT TTCCGTTACG CCGAttgccc


 


251
AaatcGCGGC GGcgaccaAa gccgaCAGTT AtgtcAGCgt ggcgcAGact


 


301
tTGGACAAGG CAGCCAAAGC CATCGGCGTG TCCTTTATCG GcggCTTTTC


 


351
CGCGCTGGTG CAAAAAGGTA TGTCGCCTTC GGATGAGGTG TTGATCCGTT


 


401
CCGTTCCCGA AGCGATGAAA ACTACCGATA TCGTGTGCAG CTCCATCAAT


 


451
ATCGGCAGCA CGCGTGCCGG TATCAATATG GATGCGGTCA AGCTGGCAGG


 


501
CGAAACCATC AAACGCACGG CTGAAATCAC ACCCGAAGGT TTCGGCTGCG


 


551
CCAAAATCGT CGTGTTCTGC AACGCGGTGG AAGACAATCC GTTTATGGCG


 


601
GGTGCGTTCC ACGGCTCGGG CGAAGCGGAT GCTGTGATTA ATGTCGGCGT


 


651
ATCCGGTCCA GGCGTGGTCA AAGCCGCGCT GGAAAATTCG GACGCGGTCA


 


701
GCCTGACCGA GGTCGCCGAA GTCGTGAAGA AAACCGCTTT CAAAATCACC


 


751
CGCGTGGGCG AACTCATCGG TCGCGAAGCC TCAAAAATGC TGAATATCCC


 


801
GTTCGGCATT CTCGATTTGT CGCTGGCACC GACCGCCGTC GTCGGCGACT


 


851
CGGTGGCGCG CATTCTTGAA GAAATGGGCT TGAGCGTCTG CGGTACGCAC


 


901
GGCACAACAG CAGCTTTGGC ATTGCTGAAC GATGCCGTGA AAAAGGGCGG


 


951
CATGATGGCT TCCAGCGCGG TCGGCGGTTT GAGCGGCGCG TTTATCCCCG


 


1001
TTTCCGAAGA CGAAGGTATG ATTGCCGCCG CCGAGGCAGG CGTGTTGACG


 


1051
CTGGACAAAC TCGAAGCCAT GACCGCCGTC TGCTCCGTTG GTTTGGACAT


 


1101
GATTGCCGTT CCCGGCGACA CGCCCGCGCA CACCATTTCC GGCATCATCG


 


1151
CCGACGAAGC CGCCATCGGC ATGATCAACA GCAAAACCAC CGCCGTGCGC


 


1201
ATTATTCCGG TAACGGGCAA AACCGTCGGC GACAGCGTCG AGTTCGGCGG


 


1251
TCTGTTGGGC TACGCGCCTG TAATGCCGGC AAAAGAAGGT TCGTGCGAAG


 


1301
TGTTCGTCAA CCGGGGCGGC AGGATTCCCG CACCGGTTCA ATCGATGAAA


 


1351
AACTGA






This corresponds to the amino acid sequence <SEQ ID 1302; ORF 312.ng>:










g312.pep




1
MSIQSGEILE TVKMVADRNF DVRTITIGID LHDCISTDID VLNQNIYNKI


 


51
TTVGKDLVAT AKHLSAKYGV PIVNQRISVT PIAQIAAATK ADSYVSVAQT


 


101
LDKAAKAIGV SFIGGFSALV QKGMSPSDEV LIRSVPEAMK TTDIVCSSIN


 


151
IGSTRAGINM DAVKLAGETI KRTAEITPEG FGCAKIVVFC NAVEDNPFMA


 


201
GAFHGSGEAD AVINVGVSGP GVVKAALENS DAVSLTEVAE VVKKTAFKIT


 


251
RVGELIGREA SKMLNIPFGI LDLSLAPTPA VGDSVARILE EMGLSVCGTH


 


301
GTTAALALLN DAVKKGGMMA SSAVGGLSGA FIPVSEDEGM IAAAEAGVLT


 


351
LDKLEAMTAV CSVGLDMIAV PGDTPAHTIS GIIADEAAIG MINSKTTAVR


 


401
IIPVTGKTVG DSVEFGGLLG YAPVMPAKEG SCEVFVNRGG RIPAPVQSMK


 


451
N*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1303>:










m312.seq




1
ATGAGTATCC AATCCGGCGA AATTTTAGAA ACCGTCAAAA TGGTTGCCGA


 


51
CCAGAATTTT GATGTCCGCA CCATTACCAT CGGCATTGAT TTGCACGACT


 


101
GCATCAGCAG CGATATCAAT GTGTTGAACC AAAATATTTA CAATAAAATT


 


151
ACCACAGTCG GCAAAGACTT GGTCACTACG GCAAAATATC TGTCTGCCAA


 


201
ATACGGCGTA CCGATTGTGA ATCAGCGCAT TTCCGTTACG CCGATTGCCC


 


251
AAATCGCGGC GGCCACCCAT GCTGATTCTT ACGTCAGCGT GGCGCAAACT


 


301
TTGGATAAAG CTGCCAAAGC CATCGGTGTG TCTTTTATCG GCGGTTTTTC


 


351
CGCGTTGGTG CAAAAAGGGA TGTCGCcTTC GGATGAGGTG TTAATCCGCT


 


401
CCATTCCCGA AGCGATGAAG ACTACCGATA TTGTGTGCwG CTCCATCAAT


 


451
ATCGGCAGTA CGCGTGCCGG TATCAATATG GATGCGGTCA AGCTGGCGGG


 


501
CGAAACcGTc AAACGCACGG CGGAAATCAC GCCCGAAGGT TTCGGCTGCG


 


551
CTAAAATTGT CGTGTTCTGC AACGCGGTGG AAGACAACCC GTTTwTGGCG


 


601
GGCGCGTTTC ATGGTTCGGG CGATGCCGTT ATCAATGTCG GCGTATCCGG


 


651
CCCAGGTGTC GTAAAAGCCG CGTTGGAAAA TTCAGATGCA ACGACATTGA


 


701
CCGAAGTTGC GGAAGTAGTG AAGAAAACTG CTTTCAAAAT TACCCGCGTG


 


751
GGCGAACTCA TCGGCCGCGA AGCcTCAAAA ATGCTGAATA TCCCGTTTGG


 


801
TATTCTCGAC TTGTCGCCGA CCCCGCCCGT CGGCGACTCA GTGGCACGCA


 


851
TTCTTGAAGA AATGGGCTTG AGCGTCTGCG GTACGCACGG CACAACAGCA


 


901
GCTTTGGCAT TGCTGAACGA TGCCGTGAAA AAAGGCGGCA TGATGGCTTC


 


951
CAGCGCGGTC GGGGGTTTGA GTGGCGCGTT TATCCCCGTT TCCGAAGACG


 


1001
AAGGTATGAT yGmCgCcGCC GAAGCAGGCG TGCTGACGCT GGACAAACTC


 


1051
GAAGCCATGA CCGCCGTTTG TTCGGTCGGC TTGGATATGA TTGCCGTTCC


 


1101
CGGCGACACG CCCGCGCACA CCATTTCCGG CATCATTGCC GACGAAGCCG


 


1151
CCATCGGCAt GATCAACAGC AAAACCACTG CCGTGCGCAT TATTCCGGTA


 


1201
ACCGGTAAAA CCGTCGGCGA CAcGGTCGAG TTCGGCGGCT TGTTGGgCTA


 


1251
CGCGCCTGTG ATGCCGGTCA AAGAAGGTTC GTGCGAAGTA TTCGTCAACC


 


1301
GAGGCGGCAG AATTCCGGCT CCGGTTCAAT CGATGAAAAA CTGA






This corresponds to the amino acid sequence <SEQ ID 1304; ORF 312>:










m312.pep




1
MSIQSGEILE TVKMVADQNF DVRTITIGID LHDCISSDIN VLNQNIYNKI


 


51
TTVGKDLVTT AKYLSAKYGV PIVNQRISVT PIAQIAAATH ADSYVSVAQT


 


101
LDKAAKAIGV SFIGGFSALV QKGMSPSDEV LIRSIPEAMK TTDIVCXSIN


 


151
IGSTRAGINM DAVKLAGETV KRTAEITPEG FGCAKIVVFC NAVEDNPFXA


 


201
GAFHGSGDAV INVGVSGPGV VKAALENSDA TTLTEVAEVV KKTAFKITRV


 


251
GELIGREASK MLNIPFGILD LSPTPPVGDS VARILEEMGL SVCGTHGTTA


 


301
ALALLNDAVK KGGMMASSAV GGLSGAFIPV SEDEGMIXAA EAGVLTLDKL


 


351
EAMTAVCSVG LDMIAVPGDT PAHTISGIIA DEAAIGMINS KTTAVRIIPV


 


401
TGKTVGDTVE FGGLLGYAPV MPVKEGSCEV FVNRGGRIPA PVQSMKN*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 312 shows 95.6% identity over a 451 aa overlap with a predicted ORF (ORF 312.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1305>:










a312.seq




1
ATGAGTATCC AATCCGGCGA AATTTTAGAA ACCGTCAAAA TGGTTGCCGA


 


51
CCAGAATTTC GATGTCCGCA CCATTACCAT CGGCATTGAT TTGCACGACT


 


101
GCATCAGCAC CGACATCGAC GTGTTGAACC AAAATATTTA CAACAAAATT


 


151
ACCACGGTCG GCAAAGACTT GGTGGCGACA GCAAAATATC TGTCTGCCAA


 


201
ATACGGCGTG CCGATTGTGA ATCAGCGCAT TTCTGTCACG CCGATTGCCC


 


251
AAATCGCGGC GGCCACCCAT GCTGATTCTT ACGTCAGCGT GGCGCAAACT


 


301
TTGGATAAGG CTGCCAAAGC CATCGGCGTG TCTTTTATTG GCGGCTTTTC


 


351
CGCGCTGGTG CAAAAAGGTA TGTCGCCTTC TGACGAGGTG TTAATCCGTT


 


401
CCATTCCCGA AGCGATGAAG ACTACTGATA TCGTGTGCAG CTCCATCAAT


 


451
ATCGGCAGTA CGCGCGCCGG TATCAATATG GACGCGGTCA GACTGGCGGG


 


501
CGAAACCATC AAACGCACGG CTGAAATCAC ACTAGAAGGT TTCGGCTGCG


 


551
CCAAAATCGT CGTGTTCTGC AACGCGGTGG AAGACAACCC GTTTATGGCG


 


601
GGCGCGTTTC ACGGCTCAGG CGAAGCGGAT GCTGTGATTA ATGTCGGCGT


 


651
ATCCGGCCCG GGTGTCGTAA AAGCCGCGTT GGAAAATTCG GATGCAACGA


 


701
CATTGACCGA AGTTGCCGAA GTTGTGAAGA AAACCGCCTT CAAAATTACC


 


751
CGCGTGGGCG AACTCATCGG CCGCGAAGCC TCAAAAATGC TGAATATCCC


 


801
GTTTGGTATT CTCGACTTGT CGCTGGCACC GACCCCTGCC GTCGGCGACT


 


851
CGGTGGCGCG CATTCTTGAA GAAATGGGTT TGAGCGTCTG CGGTACGCAC


 


901
GGCACAACAG CAGCTTTGGC ATTGCTGAAC GATGCCGTGA AAAAGGGCGG


 


951
CATGATGGCT TCGAGCGCGG TTGGCGGTTT GAGTGGCGCG TTTATCCCCG


 


1001
TTTCCGAAGA CGAAGGTATG ATTGCCGCCG CCGAAGCAGG CGTGCTGACG


 


1051
TTGGATAAAC TCGAAGCGAT GACCGCCGTT TGTTCGGTCG GCTTGGATAT


 


1101
GATTGCCGTT CCCGGCGACA CACCCGCGCA CACCATTTCC GGCATCATTG


 


1151
CCGACGAAGC CGCCATCGGC ATGATCAACA GCAAAACCAC TGCCGTGCGC


 


1201
ATTATTCCGG TAACCGGTAA AACCGTCGGC GACAGCGTCG AGTTCGGCGG


 


1251
CCTGTTGGGC TACGCGCCTG TAATGCCGGT AAAAGAAGGC TCATGCGAAG


 


1301
TGTTCGTCAA CCGGGGCGGC AGGATTCCCG CACCGGTTCA ATCGATGAAA


 


1351
AACTGA






This corresponds to the amino acid sequence <SEQ ID 1306; ORF 312.a>:










a312.pep




1
MSIQSGEILE TVKMVADQNF DVRTITIGID LHDCISTDID VLNQNIYNKI


 


51
TTVGKDLVAT AKYLSAKYGV PIVNQRISVT PIAQIAAATH ADSYVSVAQT


 


101
LDKAAKAIGV SFIGGFSALV QKGMSPSDEV LIRSIPEAMK TTDIVCSSIN


 


151
IGSTRAGINM DAVRLAGETI KRTAEITLEG FGCAKIVVFC NAVEDNPFMA


 


201
GAFHGSGEAD AVINVGVSGP GVVKAALENS DATTLTEVAE VVKKTAFKIT


 


251
RVGELIGREA SKMLNIPFGI LDLSLAPTPA VGDSVARILE EMGLSVCGTH


 


301
GTTAALALLN DAVKKGGMMA SSAVGGLSGA FIPVSEDEGM IAAAEAGVLT


 


351
LDKLEAMTAV CSVGLDMIAV PGDTPAHTIS GIIADEAAIG MINSKTTAVR


 


401
IIPVTGKTVG DSVEFGGLLG YAPVMPVKEG SCEVFVNRGG RIPAPVQSMK


 


451
N*






m312/a312 96.7% identity in 451 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1307>:










g313.seq




1
atggacgacc cgcgcaccta cggatcgggc aatcccggcg cgaccaatgt


 


51
tttacgcagc ggcaaaaaaa aggcggccgc gctgacgctc ttgggcgatg


 


101
ccgccaaagg tttggttgcc gttttgcttg cacgcgtgct tcaagaaccg


 


151
ctcggtttat ccgacagcgc aatcgccgcc gtcgcactcg ccgcgctggt


 


201
cgggcatatg tggccggtgt ttttcggatt taagggcggc aaaggcgtgg


 


251
caacggcatt gggcgtgctt ctggcactct ctcctgcaac tgccttggtc


 


301
tgcgcgttga tttggcttgt gatggcattc ggcttcaaag tatcctccct


 


351
tgccgcgctg gtcgccacaa ccgccgcccc ccttgccgca ctgtttttta


 


401
tgccgcatac ttcttggatt ttcgcaaccc tcgcaatcgc catattggtg


 


451
ttgctccgcc ataagagcaa catcctcaac ctgattaaag gcaaagaaag


 


501
caaaatcggc gaaaaacgct ga






This corresponds to the amino acid sequence <SEQ ID 1308; ORF 313.ng>:










g313.pep




1
MDDPRTYGSG NPGATNVLRS GKKKAAALTL LGDAAKGLVA VLLARVLQEP


 


51
LGLSDSAIAA VALAALVGHM WPVFFGFKGG KGVATALGVL LALSPATALV


 


101
CALIWLVMAF GFKVSSLAAL VATTAAPLAA LFFMPHTSWI FATLAIAILV


 


151
LLRHKSNILN LIKGKESKIG EKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1309>:










m313.seq




1
ATGGACGACC CGCGCACCTA CGGATCGGGC AATCCGGGGG CAACCAATGT


 


51
TTTACGCAGC GGCAAAAAAA AGGCGGCCGC GCTGACGCTC TTGGGCGATG


 


101
CCGCCAAAGG TTTAGTTGCC GTTTTGCTTG CACGCGTGCT TCAAGAACCG


 


151
CTCGGTTTAT CCGACAGCGC AATCGCGGCC GTCGCACTCG CCGCGCTGGT


 


201
CGGGCATATG TGGCCGGTGT TTTTCGGATT TAAAGGCGGC AAAGGCGTGG


 


251
CAACGGCATT GGGCGTGCTT CTGGCACTCT CTCCCGCAAC TGCCTTGGTC


 


301
TGCGCGTTGA TTTGGCTTGT TATGGCATTC GGCTTCAAGG TGTCCTCCCT


 


351
TGCCGCATTA ACCGCCACAA TCGCCGCACC GGTCGCCGCA TCCTTCTTTA


 


401
TGCCGCACGT CTCGTGGGTT TGGGCGACCG TCGCCATTGC TTTGCTGGTG


 


451
TTGTTCCGCC ACAAAAGTAA TATCGTCAAG CTGCTCGAAG GCAGAGAAAG


 


501
CAAAATCGGC GGCAGCCGCT GA






This corresponds to the amino acid sequence <SEQ ID 1310; ORF 313>:










m313.pep




1
MDDPRTYGSG NPGATNVLRS GKKKAAALTL LGDAAKGLVA VLLARVLQEP


 


51
LGLSDSAIAA VALAALVGHM WPVFFGFKGG KGVATALGVL LALSPATALV


 


101
CALIWLVMAF GFKVSSLAAL TATIAAPVAA SFFMPHVSWV WATVAIALLV


 


151
LFRHKSNIVK LLEGRESKIG GSR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 313 shows 90.2% identity over a 173 aa overlap with a predicted ORF (ORF 313.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1311>:










a313.seq




1
ATGGACGACC CGCGCACCTA CGGATCGGGC AATCCGGGGG CAACCAATGT


 


51
TTTACGCAGC GGCAAAAAAA AGGCGGCCGC GCTGACGCTC TTGGGCGATG


 


101
CCGCCAAAGG TTTGGTTGCC GTTTTGCTTG CACGCGTGCT TCAAGAACCG


 


151
CTCGGTTTAT CCGACAGCGC AATCGCGGCC GTCGCACTCG CCGCGCTGGT


 


201
CGGGCATATG TGGCCGGTGT TTTTCGGATT TAAAGGCGGC AAAGGCGTGG


 


251
CAACGGCATT GGGCGTGCTT CTGGCACTCT CTCCCACAAC TGCCTTGGTC


 


301
TGCGCGTTGA TTTGGCTTGT GATGGCATTC GGCTTCAAGG TGTCCTCCCT


 


351
TGCCGCATTA ACCGCCACAA TCGCCGCCCC CCTTGCCGCA CTGTTTTTTA


 


401
TGCCGCATAC TTCTTGGATT TTCGCAACCC TCGCAATCGC CATATTGGTG


 


451
TTGCTCCGCC ATAAGAGCAA CATCCTCAAC CTGATTAAAG GCAAAGAAAG


 


501
CAAAATCGGC GAAAAACGCT GA






This corresponds to the amino acid sequence <SEQ ID 1312; ORF 313.a>:










a313.pep




1
MDDPRTYGSG NPGATNVLRS GKKKAAALTL LGDAAKGLVA VLLARVLQEP


 


51
LGLSDSAIAA VALAALVGHM WPVFFGFKGG KGVATALGVL LALSPTTALV


 


101
CALIWLVMAF GFKVSSLAAL TATIAAPLAA LFFMPHTSWI FATLAIAILV


 


151
LLRHKSNILN LIKGKESKIG EKR*






m313/a313 90.8% identity in 173 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1313>:










g401.seq




1
atgaaattac aacaattggc tgaagaaaaa atcggcgttc tgattgtgtt


 


51
cacgctgctt gtagtcagtg tcggtctgtt gattgaagtt gtgcccttgg


 


101
cctttaccaa ggcggcaaca cagccggcgc cgggcgtgaa gccttacaat


 


151
gccctgcagg ttgccggacg cgatatttac atccgtgagg gctgttacaa


 


201
ctgccactct caaatgattc gtccgttccg tgcggaaacc gagcgttacg


 


251
gtcattactc tgttgccgga gagtcggttt acgaccatcc gttccaatgg


 


301
ggttccaaac gtaccggtcc tgatttggca cgtgtgggcg gccgctattc


 


351
cgacgaatgg caccgcatcc acctgctgaa tccccgtgat gtcgtgcctg


 


401
agtccaatat gccggcattc ccgtggcttg cacgcaataa agtcgatgtc


 


451
gatgcaaccg ttgccaacat gaaggctttg cgtaaagtag gtactcctta


 


501
cagtgatgag gaaattgcga aagcgcctga ggctttggca aacaaatccg


 


551
agctggatgc tgtagtcgcc tatctgcaag gattgggtct ggctttgaaa


 


601
aacgtaaggt aa






This corresponds to the amino acid sequence <SEQ ID 1314; ORF 401.ng>:










g401.pep




1
MKLQQLAEEK IGVLIVFTLL VVSVGLLIEV VPLAFTKAAT QPAPGVKPYN


 


51
ALQVAGRDIY IREGCYNCHS QMIRPFRAET ERYGHYSVAG ESVYDHPFQW


 


101
GSKRTGPDLA RVGGRYSDEW HRIHLLNPRD VVPESNMPAF PWLARNKVDV


 


151
DATVANMKAL RKVGTPYSDE EIAKAPEALA NKSELDAVVA YLQGLGLALK


 


201
NVR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1315>:










m401.seq




1
ATGAAATTAC AaCAATTGGC TGAAGAAAAA ATCGGCGTTC TGATTGTGTT


 


51
CACGCTGCTT GTAGTCAGTG TCGGTCTGTT GATTGAAGTT GTGCCCTTGG


 


101
CCTTTACCAA GGCGGCAACA CAGCCGGCGC CGGGCGTGAA GCCTTACAAT


 


151
GCCCTGCAGG TTGCCGGACG CGATATTTAC ATCCGTGAGG GCTGTTACAA


 


201
CTGCCACTCG CAAATGATTC GTCCGTTCCG TGCGGAAACC GAGCGTTACG


 


251
GTCATTACTC TGTTGCCGGA GAGTCGGTTT ACGACCATCC GTTCCAATGG


 


301
GGTTCCAAAC GTACCGGTCC TGATTTGGCA CGTGTGGGCG GTCGCTATTC


 


351
CGACGAATGG CACCGTATCC ACCTGCTGAA TCCCCGTGAT GTCGTGCCTG


 


401
AGTCCAATAT GCCGGCATTC CCGTGGCTTG CACGCAATAA AGTCGATGTC


 


451
GATGCAACCG TTGCCAACAT GAAGGCTTTG CGTAAAGTAG GTACTCCTTA


 


501
CAGTGATGAG GAAATTGCGA AAGCACCTGA GGCTTTGGCA AACAAATCCG


 


551
AGCTGGATGC TGTAGTCGCC TATCTGCAAG GATTGGGTCT GGCTTTGAAA


 


601
AACGTAAGGT AA






This corresponds to the amino acid sequence <SEQ ID 1316; ORF 401>:










m401.pep




1
MKLQQLAEEK IGVLIVFTLL VVSVGLLIEV VPLAFTKAAT QPAPGVKPYN


 


51
ALQVAGRDIY IREGCYNCHS QMIRPFRAET ERYGHYSVAG ESVYDHPFQW


 


101
GSKRTGPDLA RVGGRYSDEW HRIHLLNPRD VVPESNMPAF PWLARNKVDV


 


151
DATVANMKAL RKVGTPYSDE EIAKAPEALA NKSELDAVVA YLQGLGLALK


 


201
NVR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 401 shows 100.0% identity over a 203 aa overlap with a predicted ORF (ORF 401.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1317>:










a401.seq




1
ATGAAATTAC AACAATTGGC TGAAGAAAAA ATCGGCGTTC TGATTGTGTT


 


51
CACGCTGCTT GTAGTCAGTG TCGGTCTGTT GATTGAAGTT GTGCCCTTGG


 


101
CCTTTACCAA GGCGGCAACA CAGCCGGCGT CGGGCGTGAA GCCTTACAAT


 


151
GCCCTGCAGG TTGCCGGACG CGATATTTAC ATCCGTGAGG GCTGTTACAA


 


201
CTGCCACTCG CAAATGATTC GTCCGTTCCG TGCGGAAACC GAGCGTTACG


 


251
GTCATTACTC TGTTGCCGGA GAGTCGGTTT ACGACCATCC GTTCCAATGG


 


301
GGTTCCAAAC GTACCGGTCC TGATTTGGCA CGTGTGGGCG GTCGCTATTC


 


351
CGACGAATGG CACCGTATCC ACCTGCTGAA TCCCCGTGAT GTCGTGCCTG


 


401
AGTCCAATAT GCCGGCATTC CCGTGGCTTG CACGCAATAA AGTCGATGTC


 


451
GATGCAACCG TTGCCAACAT GAAGGCTTTG CGTAAAGTAG GTACTCCTTA


 


501
CAGTGATGAG GAAATTGCGA AAGCGCCTGA GGCTTTGGCA AACAAATCCG


 


551
AGCTGGATGC TGTAGTCGCC TATCTGCAAG GATTGGGTCT GGCTTTGAAA


 


601
AACGTAAGGT AA






This corresponds to the amino acid sequence <SEQ ID 1318; ORF 401.a>:










a401.pep




1
MKLQQLAEEK IGVLIVFTLL VVSVGLLIEV VPLAFTKAAT QPASGVKPYN


 


51
ALQVAGRDIY IREGCYNCHS QMIRPFRAET ERYGHYSVAG ESVYDHPFQW


 


101
GSKRTGPDLA RVGGRYSDEW HRIHLLNPRD VVPESNMPAF PWLARNKVDV


 


151
DATVANMKAL RKVGTPYSDE EIAKAPEALA NKSELDAVVA YLQGLGLALK


 


201
NVR*






m401/a401 99.5% identity in 203 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1319>:










g402.seq




1
ATGGATATGG TGAACACTAA Accgaatact agtgtgatta atatgctttc


 


51
tttccttacc ggatTATTGA GCTTGGGTat agaagtCtTg tGGGTAAGGA


 


101
TGttttcgTT CGCagcAcag tccgtgcctc aggCATTTTC atttattctt


 


151
gcctGttttc tgACCGgtat cgccgtcggc gCgTATTTTG GCAAACGGAT


 


201
TTGCCGCAGC CGCTTTGTTG ATATTCCctT TATCGGGCAG TgcttcttgT


 


251
GGGCGGGTAT TgccgaTttt ttgatTTTGG GTGCTGCGTG GTTGTTGACG


 


301
GGTTTTTccg gtttcGTCCA CCACGCCGGT AtttTCATTA CCCTgtctgc


 


351
CGtcGTCAGG GGGTTGATTT TCCCACTTGT ACACCATgtg GGTACGGATG


 


401
GCAACAAATC CGGACGACAG GTTTCCAATG TTTATTTCGC CAACGTTGCC


 


451
GGCAGTGCAT TGGGTCCGGT CCTTATCGGC TTTGTGATAC TTGATttgtt


 


501
gTCCACCCAA CAGATTtacc tgctcatCTG TTTGATTTCT GCTGCtgtcc


 


551
cTTTGTTTTg tacaCTGtTC CAAAAAAGTC TCCGACTGAA TGCAGTGTCG


 


601
GTAGCAGTTT CCCTAATGTT CGGCATCCTC ATGTTCCTAC TGCCGGATTC


 


651
TGTCTTTCAA AATATTGCTG GCCGTCCGGA TAGGTTGATT GAAAACAAAC


 


701
ACGGCATTGT TGCGGTTTAC CATAGAGATG GTGATAAGGT TGTTTATGGG


 


751
GCGAATGTAT ACGACGGCGC ATACAATACC GATATATTCA ATAGTGTCAA


 


801
CGGCATCGAA CGTGCCTATC TGCTACCCTC CCTGAAGTCC GGCATACGCC


 


851
GCATTTTCGT CGTTGGATTG AGTACAGGTT CGTGGGCGCG CGTCTTGTCT


 


901
GCCATTCCGG AAATGCAGTC GATGATCGTT GCGGAAATCA ATCCGGCATA


 


951
CCGTAGCCTT ATCGCGGAcg agccgcAAAT CGCACCGCTT TTGCAGGACA


 


1001
AACGTGTTGA AATTGTATTG GATGACGGTA GGAAATGGCT GCGTCGCCAT


 


1051
CCTGATGAAA AATTCGACCT GATTTTGATG AATTCGACTT GGTACTGGCG


 


1101
TGCCTATTCC ACTAACCTGT TGAGTGCGGA ATTTTTAAAA CAGGTGCAAA


 


1151
GCCACCTTAC CCCGGATGGT ATTGTAATGT TTAATACCAC GCACAGCCCG


 


1201
CATgctTTTG CTACCGCCGT ACACAGTATT CCCTATGCAT ACCGCTACGG


 


1251
GCATATGGTA GTCGGCTCGG CAACCCCGGT AGTTTTCcct AATAAAGAAC


 


1301
TGCTCaagca aCGCCTTTcc cgGTTGATTT GGCCGGAAAG CGGCAGgcac


 


1351
gtATTTGACA GCAGCACCGT GGATGCTGCA GCACAAAAGG TTGtctctCG


 


1401
TATGCTGATT CGGATGACGG AAcctTCGGC TGGGGCGGAA GTCATTACTG


 


1451
ACGATAATAT GATTGTAGAA TACAAATACG GCAGAGGGAT TTAA






This corresponds to the amino acid sequence <SEQ ID 1320; ORF 402.ng>:










g402.pep




1
MDMVNTKPNT SVINMLSFLT GLLSLGIEVL WVRMFSFAAQ SVPQAFSFIL


 


51
ACFLTGIAVG AYFGKRICRS RFVDIPFIGQ CFLWAGIADF LILGAAWLLT


 


101
GFSGFVHHAG IFITLSAVVR GLIFPLVHHV GTDGNKSGRQ VSNVYFANVA


 


151
GSALGPVLIG FVILDLLSTQ QIYLLICLIS AAVPLFCTLF QKSLRLNAVS


 


201
VAVSLMFGIL MFLLPDSVFQ NIAGRPDRLI ENKHGIVAVY HRDGDKVVYG


 


251
ANVYDGAYNT DIFNSVNGIE RAYLLPSLKS GIRRIFVVGL STGSWARVLS


 


301
AIPEMQSMIV AEINPAYRSL IADEPQIAPL LQDKRVEIVL DDGRKWLRRH


 


351
PDEKFDLILM NSTWYWRAYS TNLLSAEFLK QVQSHLTPDG IVMFNTTHSP


 


401
HAFATAVHSI PYAYRYGHMV VGSATPVVFP NKELLKQRLS RLIWPESGRH


 


451
VFDSSTVDAA AQKVVSRMLI RMTEPSAGAE VITDDNMIVE YKYGRGI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1321>:










m402.seq




1
ATGGATATAG TGAACACTAA ACCGAATACT AGTTTGATTT ATATGCnTTC


 


51
TTTCCTTAGC GGCTTATTGA GCTTGGGTAT AGAAGTCTTG TGGGTGAGGA


 


101
TGTTTTCGTT CGCAGCACAG TCCGTGCCTC AGGCATTTTC ATTTACCCTT


 


151
GCCTGTTTTC TGACCGGTAT CGCCGTCGGC GCGTATTTTG GCAAACGGAT


 


201
TTGCCGCAGC CGCTTTGTTG ATATTCCCTT TATCGGGCAG TGCTTCTTGT


 


251
GGGCGGGTAT TGCCGACTTT TTGATTTTGG GTGCTGCGTG GTTGTTGACG


 


301
GGTTTTTCCG GCTTCGTCCA CCACGCCGGT ATCTTCATTA CCCTGTCTGC


 


351
CGTCGTCAsA sGGTTGATTT TCCCGCTCGT ACACCATGTG GGTACGGATG


 


401
GCAACAAATC CGGACGACAG GTTTCCAATG TTTATTTCGC CAmCGTTGCC


 


451
GGCAGTGCAT TGGGTCCGGT CCTTATCGGC TTTGTGATAC TTGATTTCTT


 


501
GTCCACCCAA CAGATTTACC TGCTCATCTG TwTGATTTCT GCTGCTGTCC


 


551
CTTTGTTTTG TACACTGTTC CAAAAAAGTC TCCGACTGAA TGCAGTGTCG


 


601
GTAGCAGTTT CCCTAATGTT CGGCATCCTC ATGTTCyTAC TGCCGGATTC


 


651
TGTCTTTCAA AATATTGCTG ACCGTCCGGA TAgGCTGATT GAAAACAAAC


 


701
ACGGCATTGT TGCGGTTTAC CATAGAGATG GTGATAAGGT TGTTTATGGG


 


751
GCGAATGTAT ACGACGGCGC ATACAATACC GATGTATTCA ATAGTGTCAA


 


801
CGGCATCGAA CGTGCCTATC TGCTACCCTC CCTGAAGTCT GGCATACGCC


 


851
GCATTTTCGT CGTTGGACTG AGTACAGGTT CGTGGGCGCG CGTCTTGTCT


 


901
GCCATTCCGG AAATGCAGTC GATGATCGTT GCGGAAATCA ATCCGGCATA


 


951
CCGTAGCCTT ATCGCGGACG AGCCGCAAAT CGCCCCGCTT TTGCAGGACA


 


1001
AACGTGTTGA AATTGTATTG GATGACGGTA GGAAATGGCT GCGTCGCCAT


 


1051
CCTGATGAAA AATTCGACCT GATTTTGATG AATACGACTT GGTACTGGCG


 


1101
TGCCTATTCC ACCAACCTGT TGAGTGCGGA ATTTTTAAAA CAGGTGCAAA


 


1151
GCCACCTTAC CCCGGATGGT ATTGTAATGT TTAATACCAC GCACAGCCCG


 


1201
CATGCTTTTG CTACCGCCGT ACACAGTATT CCCTATGCAT ACCGCTATGG


 


1251
GCATATGGTA GTCGGCTCGG CAACCCCGGT AGTTTTCCCT AATAAAGAAC


 


1301
TGCTCAAGCA ACGTCTCTCC CGGTTGATTT GGCCGGAAAG CGGCAGGCAC


 


1351
GTATTTGACA GCAGCACCGT GGATGCTGCA GCACAAAAGG TTGTCTCTCG


 


1401
TATGCTGATT CAGATGACGG aAcCTTCGGC TGGGGCGGAA GTTATTACCG


 


1451
ACGATAATAT GATTGTAGAA TACAAATACG GCAGAGGGAT TTAA






This corresponds to the amino acid sequence <SEQ ID 1322; ORF 402>:










m402.pep




1
MDIVNTKPNT SLIYMXSFLS GLLSLGIEVL WVRMFSFAAQ SVPQAFSFTL


 


51
ACFLTGIAVG AYFGKRICRS RFVDIPFIGQ CFLWAGIADF LILGAAWLLT


 


101
GFSGFVHHAG IFITLSAVVX XLIFPLVHHV GTDGNKSGRQ VSNVYFAXVA


 


151
GSALGPVLIG FVILDFLSTQ QIYLLICXIS AAVPLFCTLF QKSLRLNAVS


 


201
VAVSLMFGIL MFLLPDSVFQ NIADRPDRLI ENKHGIVAVY HRDGDKVVYG


 


251
ANVYDGAYNT DVFNSVNGIE RAYLLPSLKS GIRRIFVVGL STGSWARVLS


 


301
AIPEMQSMIV AEINPAYRSL IADEPQIAPL LQDKRVEIVL DDGRKWLRRH


 


351
PDEKFDLILM NTTWYWRAYS TNLLSAEFLK QVQSHLTPDG IVMFNTTHSP


 


401
HAFATAVHSI PYAYRYGHMV VGSATPVVFP NKELLKQRLS RLIWPESGRH


 


451
VFDSSTVDAA AQKVVSRMLI QMTEPSAGAE VITDDNMIVE YKYGRGI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 402 shows 97.0% identity over a 497 aa overlap with a predicted ORF (ORF 402.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1323>:










a402.seq




1
ATGGATATAG TGAACACTAA ACCGAATACT AGTTTGATTT ATATGCTTTC


 


51
TTTCCTTAGC GGCTTATTGA GCTTGGGTAT AGAAGTCTTG TGGGTAAGGA


 


101
TGTTTTCGTT CGCAGCACAG TCCGTGCCTC AGGCATTTTC ATTTACTCTT


 


151
GCCTGTTTTC TGACCGGTAT CGCCGTCGGC GCGTATTTTG GCAAACGGAT


 


201
TTGCCGCAGC CGCTTTGTTG ATATTCCCTT TATCGGGCAG TGCTTCTTGT


 


251
GGGCGGGTAT TGCCGACTTT TTGATTTTGG GTGCTGCGTG GTTGTTGACG


 


301
GGTTTTTCCG GCTTCGTCCA CCACGCCGGT ATCTTCATTA CCCTGTCTGC


 


351
CGTCGTCAGA GGGTTGATTT TCCCGCTCGT ACACCATGTG GGTACGGATG


 


401
GCAACAAATC CGGACGACAG GTTTCCAATG TTTATTTCGC CAACGTTGCC


 


451
GGCAGTGCAT TGGGTCCGGT CCTTATCGGC TTTGTGATAC TTGATTTCTT


 


501
GTCCACCCAA CAGATTTACC TGCTCATCTG TTTGATTTCT GCTGCTGTCC


 


551
CTTTGTTTTG TACACTGTTC CAAAAAAGTC TCCGACTGAA TGCAGTGTCG


 


601
GTAGCAGTTT CCCTAATGTT CGGCATCCTC ATGTTCCTAC TGCCGGATTC


 


651
TGTCTTTCAA AATATTGCTG ACCGTCCGGA TAGGCTGATT GAAAACAAAC


 


701
ACGGCATTGT TGCGGTTTAC CATAGAGATG GTGATAAGGT TGTTTATGGG


 


751
GCGAATGTAT ACGACGGCGC ATACAATACC GATGTATTCA ATAGTGTCAA


 


801
CGGCATCGAA CGTGCCTATC TGCTACCCTC CCTGAAGTCT GGCATACGCC


 


851
GCATTTTCGT CGTTGGATTG AGTACAGGTT CGTGGGCGCG CGTCTTGTCT


 


901
GCCATTCCGG AAATGCAGTC GATGATCGTT GCGGAAATCA ATCCGGCATA


 


951
CCGTAGCCTT ATCGCGGACG AGCCGCAAAT CGCCCCGCTT TTGCAGGACA


 


1001
AACGTGTTGA AATTGTATTG GATGACGGTA GGAAATGGCT GCGTCGCCAT


 


1051
CCTGATGAAA AATTCGACCT GATTTTGATG AATACGACTT GGTACTGGCG


 


1101
TGCCTATTCC ACCAACCTGT TGAGTGCGGA ATTTTTAAAA CAGGTGCAAA


 


1151
GCCACCTTAC CCCGGATGGT ATTGTAATGT TTAATACCAC GCACAGCCCG


 


1201
CATGCTTTTG CTACCGCCGT ACACAGTATT CCCTATGCAT ACCGCTATGG


 


1251
GCATATGGTA GTCGGCTCGG CAACCCCGGT AGTTTTCCCT AATAAAGAAC


 


1301
TGCTCAAGCA ACGTCTCTCC CGGTTGATTT GGCCGGAAAG CGGCAGGCAC


 


1351
GTATTTGACA GCAGCACCGT GGATGCTGCA GCACAAAAGG TTGTCTCTCG


 


1401
TATGCTGATT CAGATGACGG AACCTTCGGC TGGTGCGGAA GTCATTACCG


 


1451
ACGATAATAT GATTGTAGAA TACAAATACG GCAGAGGGAT TTAA






This corresponds to the amino acid sequence <SEQ ID 1324; ORF 402.a>:










a402.pep




1
MDIVNTKPNT SLIYMLSFLS GLLSLGIEVL WVRMFSFAAQ SVPQAFSFTL


 


51
ACFLTGIAVG AYFGKRICRS RFVDIPFIGQ CFLWAGIADF LILGAAWLLT


 


101
GFSGFVHHAG IFITLSAVVR GLIFPLVHHV GTDGNKSGRQ VSNVYFANVA


 


151
GSALGPVLIG FVILDFLSTQ QIYLLICLIS AAVPLFCTLF QKSLRLNAVS


 


201
VAVSLMFGIL MFLLPDSVFQ NIADRPDRLI ENKHGIVAVY HRDGDKVVYG


 


251
ANVYDGAYNT DVFNSVNGIE RAYLLPSLKS GIRRIFVVGL STGSWARVLS


 


301
AIPEMQSMIV AEINPAYRSL IADEPQIAPL LQDKRVEIVL DDGRKWLRRH


 


351
PDEKFDLILM NTTWYWRAYS TNLLSAEFLK QVQSHLTPDG IVMFNTTHSP


 


401
HAFATAVHSI PYAYRYGHMV VGSATPVVFP NKELLKQRLS RLIWPESGRH


 


451
VFDSSTVDAA AQKVVSRMLI QMTEPSAGAE VITDDNMIVE YKYGRGI*






m402/a402 99.0% identity in 497 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1325>:










g406.seq




1
ATGCGGGCAC GGCTGCTGAT ACCTATTCTT TTTTCAGTTT TTATTTTATC


 


51
CGCCTGCGGG ACACTGACAG GTATTCCATC GCATGGCGGA GGCAAACGCT


 


101
TCGCGGTCGA ACAAGAACTT GTGGCCGCTT CTGCCAGAGC TGCCGTTAAA


 


151
GACATGGATT TACAGGCATT ACACGGACGA AAAGTTGCAT TGTACATTGC


 


201
AACTATGGGC GACCAAGGTT CAGGCAGTTT GACAGGGGGT CGCTACTCCA


 


251
TTGATGCACT GATTCGCGGC GAATACATAA ACAGCCCTGC CGTCCGCACC


 


301
GATTACACCT ATCCGCGTTA CGAAACCACC GCTGAAACAA CATCAGGCGG


 


351
TTTGACGGGT TTAACCACTT CTTTATCTAC ACTTAATGCC CCTGCACTCT


 


401
CGCGCACCCA ATCAGACGGT AGCGGAAGTA GGAGCAGTCT GGGCTTAAAT


 


451
ATTGGCGGGA TGGGGGATTA TCGAAATGAA ACCTTGACGA CCAACCCGCG


 


501
CGACACTGCC TTTCTTTCCC ACTTGGTGCA GACCGTATTT TTCCTGCGCG


 


551
GCATAGACGT TGTTTCTCCT GCCAATGCCG ATACAGATGT GTTTATTAAC


 


601
ATCGACGTAT TCGGAACGAT ACGCAACAGA ACCGAAATGC ACCTATACAA


 


651
TGCCGAAACA CTGAAAGCCC AAACAAAACT GGAATATTTC GCAGTAGACA


 


701
GAACCAATAA AAAATTGCTC ATCAAACCCA AAACCAATGC GTTTGAAGCT


 


751
GCCTATAAAG AAAATTACGC ATTGTGGATG GGGCCGTATA AAGTAAGCAA


 


801
AGGAATCAAA CCGACGGAAG GATTGATGGT CGATTTCTCC GATATCCAAC


 


851
CATACGGCAA TCATACGGGT AACTCCGCCC CATCCGTAGA GGCTGATAAC


 


901
AGTCATGAGG GGTATGGATA CAGCGATGAA GCAGTGCGAC AACATAGACA


 


951
AGGGCAACCT TGA






This corresponds to the amino acid sequence <SEQ ID 1326; ORF 406>:










g406.pep




1
MRARLLIPIL FSVFILSACG TLTGIPSHGG GKRFAVEQEL VAASARAAVK


 


51
DMDLQALHGR KVALYIATMG DQGSGSLTGG RYSIDALIRG EYINSPAVRT


 


101
DYTYPRYETT AETTSGGLTG LTTSLSTLNA PALSRTQSDG SGSRSSLGLN


 


151
IGGMGDYRNE TLTTNPRDTA FLSHLVQTVF FLRGIDVVSP ANADTDVFIN


 


201
IDVFGTIRNR TEMHLYNAET LKAQTKLEYF AVDRTNKKLL IKPKTNAFEA


 


251
AYKENYALWM GPYKVSKGIK PTEGLMVDFS DIQPYGNHTG NSAPSVEADN


 


301
SHEGYGYSDE AVRQHRQGQP *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1327>:










m406.seq




1
ATGCAAGCAC GGCTGCTGAT ACCTATTCTT TTTTCAGTTT TTATTTTATC


 


51
CGCCTGCGGG ACACTGACAG GTATTCCATC GCATGGCGGA GGTAAACGCT


 


101
TTGCGGTCGA ACAAGAACTT GTGGCCGCTT CTGCCAGAGC TGCCGTTAAA


 


151
GACATGGATT TACAGGCATT ACACGGACGA AAAGTTGCAT TGTACATTGC


 


201
CACTATGGGC GACCAAGGTT CAGGCAGTTT GACAGGGGGT CGCTACTCCA


 


251
TTGATGCACT GATTCGTGGC GAATACATAA ACAGCCCTGC CGTCCGTACC


 


301
GATTACACCT ATCCACGTTA CGAAACCACC GCTGAAACAA CATCAGGCGG


 


351
TTTGACAGGT TTAACCACTT CTTTATCTAC ACTTAATGCC CCTGCACTCT


 


401
CTCGCACCCA ATCAGACGGT AGCGGAAGTA AAAGCAGTCT GGGCTTAAAT


 


451
ATTGGCGGGA TGGGGGATTA TCGAAATGAA ACCTTGACGA CTAACCCGCG


 


501
CGACACTGCC TTTCTTTCCC ACTTGGTACA GACCGTATTT TTCCTGCGCG


 


551
GCATAGACGT TGTTTCTCCT GCCAATGCCG ATACAGATGT GTTTATTAAC


 


601
ATCGACGTAT TCGGAACGAT ACGCAACAGA ACCGAAATGC ACCTATACAA


 


651
TGCCGAAACA CTGAAAGCCC AAACAAAACT GGAATATTTC GCAGTAGACA


 


701
GAACCAATAA AAAATTGCTC ATCAAACCAA AAACCAATGC GTTTGAAGCT


 


751
GCCTATAAAG AAAATTACGC ATTGTGGATG GGGCCGTATA AAGTAAGCAA


 


801
AGGAATTAAA CCGACGGAAG GATTAATGGT CGATTTCTCC GATATCCGAC


 


851
CATACGGCAA TCATACGGGT AACTCCGCCC CATCCGTAGA GGCTGATAAC


 


901
AGTCATGAGG GGTATGGATA CAGCGATGAA GTAGTGCGAC AACATAGACA


 


951
AGGACAACCT TGA






This corresponds to the amino acid sequence <SEQ ID 1328; ORF 406>:










m406.pep




1
MQARLLIPIL FSVFILSACG TLTGIPSHGG GKRFAVEQEL VAASARAAVK


 


51
DMDLQALHGR KVALYIATMG DQGSGSLTGG RYSIDALIRG EYINSPAVRT


 


101
DYTYPRYETT AETTSGGLTG LTTSLSTLNA PALSRTQSDG SGSKSSLGLN


 


151
IGGMGDYRNE TLTTNPRDTA FLSHLVQTVF FLRGIDVVSP ANADTDVFIN


 


201
IDVFGTIRNR TEMHLYNAET LKAQTKLEYF AVDRTNKKLL IKPKTNAFEA


 


251
AYKENYALWM GPYKVSKGIK PTEGLMVDFS DIRPYGNHTG NSAPSVEADN


 


301
SHEGYGYSDE VVRQHRQGQP *






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB ORF 406 shows 98.8% identity over a 320 aa overlap with a predicted ORF (ORF406.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1329>:










a406.seq




1
ATGCAAGCAC GGCTGCTGAT ACCTATTCTT TTTTCAGTTT TTATTTTATC


 


51
CGCCTGCGGG ACACTGACAG GTATTCCATC GCATGGCGGA GGTAAACGCT


 


101
TCGCGGTCGA ACAAGAACTT GTGGCCGCTT CTGCCAGAGC TGCCGTTAAA


 


151
GACATGGATT TACAGGCATT ACACGGACGA AAAGTTGCAT TGTACATTGC


 


201
AACTATGGGC GACCAAGGTT CAGGCAGTTT GACAGGGGGT CGCTACTCCA


 


251
TTGATGCACT GATTCGTGGC GAATACATAA ACAGCCCTGC CGTCCGTACC


 


301
GATTACACCT ATCCACGTTA CGAAACCACC GCTGAAACAA CATCAGGCGG


 


351
TTTGACAGGT TTAACCACTT CTTTATCTAC ACTTAATGCC CCTGCACTCT


 


401
CGCGCACCCA ATCAGACGGT AGCGGAAGTA AAAGCAGTCT GGGCTTAAAT


 


451
ATTGGCGGGA TGGGGGATTA TCGAAATGAA ACCTTGACGA CTAACCCGCG


 


501
CGACACTGCC TTTCTTTCCC ACTTGGTACA GACCGTATTT TTCCTGCGCG


 


551
GCATAGACGT TGTTTCTCCT GCCAATGCCG ATACGGATGT GTTTATTAAC


 


601
ATCGACGTAT TCGGAACGAT ACGCAACAGA ACCGAAATGC ACCTATACAA


 


651
TGCCGAAACA CTGAAAGCCC AAACAAAACT GGAATATTTC GCAGTAGACA


 


701
GAACCAATAA AAAATTGCTC ATCAAACCAA AAACCAATGC GTTTGAAGCT


 


751
GCCTATAAAG AAAATTACGC ATTGTGGATG GGACCGTATA AAGTAAGCAA


 


801
AGGAATTAAA CCGACAGAAG GATTAATGGT CGATTTCTCC GATATCCAAC


 


851
CATACGGCAA TCATATGGGT AACTCTGCCC CATCCGTAGA GGCTGATAAC


 


901
AGTCATGAGG GGTATGGATA CAGCGATGAA GCAGTGCGAC GACATAGACA


 


951
AGGGCAACCT TGA






This corresponds to the amino acid sequence <SEQ ID 1330; ORF 406.a>:










a406.pep




1
MQARLLIPIL FSVFILSACG TLTGIPSHGG GKRFAVEQEL VAASARAAVK


 


51
DMDLQALHGR KVALYIATMG DQGSGSLTGG RYSIDALIRG EYINSPAVRT


 


101
DYTYPRYETT AETTSGGLTG LTTSLSTLNA PALSRTQSDG SGSKSSLGLN


 


151
IGGMGDYRNE TLTTNPRDTA FLSHLVQTVF FLRGIDVVSP ANADTDVFIN


 


201
IDVFGTIRNR TEMHLYNAET LKAQTKLEYF AVDRTNKKLL IKPKTNAFEA


 


251
AYKENYALWM GPYKVSKGIK PTEGLMVDFS DIQPYGNHMG NSAPSVEADN


 


301
SHEGYGYSDE AVRRHRQGQP *






m406/a406 98.8% identity in 320 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1331>:










g501.seq




1
atggtcggac ggaccttgac cgcagatacc gacatatttg ttctgcttgc,


 


51
ggcaggcgga gatggcaaga tgcagcatca ctttgacggc agggttgcgt


 


101
tcgtcaaacg attcggacac caagccgctg tctcggtcga ggccgagggt


 


151
cagctgggtc atgtcgttcg agccgatgga gaagccgtcg aagtattgca


 


201
ggaattgttc cgccaatacc gcgttgctcg gcagctcgca catcataatc


 


251
aggcgcaggc cgtttttgcc gcgttccaag ccgttttctt tcaatgcctt


 


301
aaccactgct tcggcttcgc ccaaagtgcg gacgaacgga atcatgattt


 


351
cgacgttggt cagacccatt tcgtcacgaa cgcgtttcaa ggctttgcat


 


401
tccaaggcga aacagtcttt gaagctctcg gcaacataac gcgccgcacc


 


451
acggaagccc aacatcgggt tttcttcatg cggttcgtat acgctgccgc


 


501
cgaccaggtt ggcgtattcg ttggatttga agtcggacat acggacgatg


 


551
gttttacgcg gataaaccga tgcggcaagc gttgccacgc cttcggcgat


 


601
tttatcgacg tagaagtcga caggggatgc gtaaccggcg atgcggcgga


 


651
taatttccgc tttcagttcg tcgtcttgtt tgtcaaattc caacaaggct


 


701
ttcgggtgga tgccgatttg gcggttgatg ataaattcca tacgcgccaa


 


751
gccgatgcct tcgctgggca gattggcgaa gctgaatgcg agttcgggat


 


801
tgccgacgtt catcatgact ttgacgggtg cttttggcat attgtccaag


 


851
gcgacatcgg taatttgtac gtccagcagg ccggcataga taaagccggt


 


901
atcgccttcg gcacaggata cggtaacttc ctgaccgttt tccaagagtt


 


951
cggtcgcatt gccgcagccg acgacggcag gaatacccag ttcgcgcgcg


 


1001
atgatggcgg cgtggcaggt gcgtccgccg cggttggtca cgatggcgga


 


1051
agcacgtttc atcacgggtt cccaatccgg atcggtcatg tcggtaacca


 


1101
gtacgtcgcc ggcttcgacg gaatccatct cggaagcatc tttaatcagg


 


1151
cgcaccttgc cctgaccgac tttttgaccg atggcacgac cttcgcacaa


 


1201
gacggttttt tcgccgttga tggcgtagcg gcgcaggttg cggctgcctt


 


1251
cttcttggga tttgacggtt tcggggcggg cttgcaggat gtagagtttg


 


1301
ccgtccaggc cgtcgcgtcc ccattcgata tccatcgggc ggccgtagtg


 


1351
tttttcgatg gtcagcgcgt agtgtgccaa ctcggtgatt tcttcgtcgg


 


1401
taatggagaa gcggttgcgg tcttcttcgg ggacttcgac gttggttacc


 


1451
gatttgccgg cttcggcttt gtcggtgaaa atcattttga tgtgtttcga


 


1501
acccatggtc ttgcgcagga tggcgggttt gcctgctttg agcgtgggtt


 


1551
tgaacacata aaattcgtcc gggttgaccg cgccttgtac gacgttttcg


 


1601
cccagaccgt aagaggaggt aacaaagacg acttggttgt agccggattc


 


1651
ggtgtcgagg gtgaacatca cacctga






This corresponds to the amino acid sequence <SEQ ID 1332; ORF 501.ng>:










g501.pep




1
MVGRTLTADT DIFVLLAAGG DGKMQHHFDG RVAFVKRFGH QAAVSVEAEG


 


51
QLGHVVRADG EAVEVLQELF RQYRVARQLA HHNQAQAVFA AFQAVFFQCL


 


101
NHCFGFAQSA DERNHDFDVG QTHFVTNAFQ GFAFQGETVF EALGNITRRT


 


151
TEAQHRVFFM RFVYAAADQV GVFVGFEVGH TDDGFTRINR CGKRCHAFGD


 


201
FIDVEVDRGC VTGDAADNFR FQFVVLFVKF QQGFRVDADL AVDDKFHTRQ


 


251
ADAFAGQIGE AECEFGIADV HHDFDGCFWH IVQGDIGNLY VQQAGIDKAG


 


301
IAFGTGYGNF LTVFQEFGRI AAADDGRNTQ FARDDGGVAG ASAAVGHDGG


 


351
STFHHGFPIR IGHVGNQYVA GFDGIHLGSI FNQAHLALTD FLTDGTTFAQ


 


401
DGFFAVDGVA AQVAAAFFLG FDGFGAGLQD VEFAVQAVAS PFDIHRAAVV


 


451
FFDGQRVVCQ LGDFFVGNGE AVAVFFGDFD VGYRFAGFGF VGENHFDVFR


 


501
THGLAQDGGF ACFERGFEHI KFVRVDRALY DVFAQTVRGG NKDDLVVAGF


 


551
GVEGEHHT*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1333>:










m501.seq




1
atggtcggac sggccttgac cgcagatgcc gacatatttg ttctgcttgc


 


51
ggcaggcgga gatggcaagg tgcagcatca ctttgacggc agggttgcgt


 


101
tcgtcaaacg attcggatac caagccgctg tcgcggtcga gaccgagggt


 


151
cagttgggtc atgtcgttcg agccgatgga gaagccgtcg aagtattgca


 


201
ggaattgttc cgccaatacc gcgttgctcg gcagctcgca catcataatc


 


251
aggcgcaggc cgtttttgcc gcgttccaag ccgttttctt tcagggcttt


 


301
gacaacggmt tcggcttcgc ccaaagtgcg gacgaacgga atcatgattt


 


351
caacgttggy caaccccatt tcatcgcgga cgcgtttcaa ggctttgcat


 


401
tccaaggcga aacagtcttt gaagttgtcg gcgacataac gcgccgcacc


 


451
acggaagccc aacatcgggt tttcttcatg cggttcgtat acgttgccgc


 


501
cgaccaggtt ggcgtattcg ttggatttga agtcggacat acggacgatg


 


551
gttttacgcg gataaaccga tgcggccaat gtcgccacgc cttcggcgat


 


601
tttatcgacg tagaagtcga caggggacgc gtaaccggcg atacggcggg


 


651
taatttccgc ttttaattcg tcgtcttgtt tgtcaaattc caacaargct


 


701
ttggggtgga taccgatttg gcggttgatg ataaattcca tacgcgccaa


 


751
gccgatgcct tcgctgggca ggttggcgaa gctgaatgcg agttcgggat


 


801
tgccgacgtt catcatgact tttacaggtg ctttaggcat attgtctaag


 


851
gcgacatcgg taatctgtac gtccaacaga ccggcataga taaagccggt


 


901
atcgccttcg gcacaggata cggtaacttc ttgaccgttt ttcagcaatt


 


951
cggttgcatt gccgcagccg acaacggcag gaatgcccaa ttcacgcgcg


 


1001
atgatggcgg cgtggcaggt acggccgccg cggttggtaa cgatggcaga


 


1051
agcacgtttc atcacgggtt cccaatccgg atcggtcatg tcggtaacga


 


1101
gtacgtcgcc ggcttcgacg gaatccatct cggaagcatc tttaatcagg


 


1151
cgcaccttgc cctgaccgac tttctgaccg atggcgcggc cttcgcataa


 


1201
tacggttttg tcgccgttga tggcgaagcg gcgcaggttg cggttgccct


 


1251
cttcttggga ttttacggtt tcgggacggg cttgcaggat gtagagtttg


 


1301
ccgtccaagc cgtcgcgtcc ccattcgata tccatcgggc ggccgtagtg


 


1351
tttttcgatg gtcagtgcgt aatgcgccaa ctcagtaatt tcttcgtcgg


 


1401
taatggagaa gcggttgcgg tcttcctcgg ggacatcgac gttggttacg


 


1451
gatttaccgg cttctgcttt gtcggtaaaa atcattttga tgtgttttga


 


1501
acccatggtt ttacgcagga tggcgggctt gcccgytttg agcgtgggtt


 


1551
tgaacacatr aaattcgtcc gggttgaccg caccttgtac gacgttttcg


 


1601
cccagaccgt aagaggaggt aacaaagacg acytgatcgt akccggattc


 


1651
ggtgtcgagg gtgaacatca cacctga






This corresponds to the amino acid sequence <SEQ ID 1334; ORF 501>:










m501.pep




1
MVGXALTADA DIFVLLAAGG DGKVQHHFDG RVAFVKRFGY QAAVAVETEG


 


51
QLGHVVRADG EAVEVLQELF RQYRVARQLA HHNQAQAVFA AFQAVFFQGF


 


101
DNGFGFAQSA DERNHDFNVG QPHFIADAFQ GFAFQGETVF EVVGDITRRT


 


151
TEAQHRVFFM RFVYVAADQV GVFVGFEVGH TDDGFTRINR CGQCRHAFGD


 


201
FIDVEVDRGR VTGDTAGNFR FXFVVLFVKF QQXFGVDTDL AVDDKFHTRQ


 


251
ADAFAGQVGE AECEFGIADV HHDFYRCFRH IVXGDIGNLY VQQTGIDKAG


 


301
IAFGTGYGNF LTVFQQFGCI AAADNGRNAQ FTRDDGGVAG TAAAVGNDGR


 


351
STFHHGFPIR IGHVGNEYVA GFDGIHLGSI FNQAHLALTD FLTDGAAFAX


 


401
YGFVAVDGEA AQVAVALFLG FYGFGTGLQD VEFAVQAVAS PFDIHRAAVV


 


451
FFDGQCVMRQ LSNFFVGNGE AVAVFLGDID VGYGFTGFCF VGKNHFDVFX


 


501
THGFTQDGGL ARFERGFEHX KFVRVDRTLY DVFAQTVRGG NKDDLIVXGF


 


551
GVEGEHHT*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 501 shows 86.2% identity over a 558 aa overlap with a predicted ORF (ORF 501.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1335>:









a501.seq (partial)










1
ATGGTCGGAC GGGCCTTGAC CGCAGATGCC GACATATTTG TTCTGCTTGC



 


51
GGCAGGCGGA GATGGCAAGG TGCAGCATCA CTTTGACGGC AGGGTTGCGT


 


101
TCGTCAAACG ATTCGGATAC CAAGCCGCTG TCGCGGTCGA GACCGAGGGT


 


151
CAGTTGGGTC ATGTCGTTCG AGCCGATGGA GAAGCCGTCG AAGTATTGCA


 


201
GGAATTGTTC CGCCAATACC GCGTTGCTCG GCAGCTCGCA CATCATAATC


 


251
AGGCGCAGGC CGTTTTTGCC GCGTTCCAAG CCGTTTTCTT TCAGGGCTTT


 


301
GACAACGGCT TCGGCTTCGC CCAAAGTGCG GACGAACGGA ATCATGATTT


 


351
CAACGTTGGT CAACCCCATT TCATCGCGGA CGCGTTTCAA GGCTTTGCAT


 


401
TCCAAGGCGA AACAGTCTTT GAAGTTGTCG GCGACATAAC GCGCCGCACC


 


451
ACGGAAGCCC AACATCGGGT TTTCTTCATG CGGTTCGTAT ACGTTGCCGC


 


501
CGACCAGGTT GGCGTATTCG TTGGATTTGA AGTCGGACAT ACGGACGATG


 


551
GTTTTACGCG GATAAACCGA TGCGGCCAAT GTCGCCACGC CTTCGGCGAT


 


601
TTTATCGACG TAGAAGTCGA CAGGGGACGC GTAACCGGCG ATACGGCGGG


 


651
TAATTTCCGC TTTTAATTCG TCGTCTTGTT TGTCAAATTC CAACAAGGCT


 


701
TTGGGGTGGA TACCGATTTG GCGGTTGATG ATAAATTCCA TACGCGCCAA


 


751
GCCGATGCCT TCGCTGGGCA GGTTGGCGAA GCTGAATGCG AGTTCGGGAT


 


801
TGCCGACGTT CATCATGACT TTTACAGGTG CTTTAGGCAT GTTGTCCAAA


 


851
GCAACATCGG TAATTTGTAC GTCCAGCAGG CCGGAGTAGA TGAAGCCGGT


 


901
ATCGCCTTCG GCACAGGATA CGGTAACTTC TTGACCGTTT TTCAGCAATT


 


951
CGGTTGCATT GCCGCAGCCG ACAACGGCAG GAATACCCAG TTCGCGCGCG


 


1001
ATGATGGCGG CGTGGCAGGT ACGTCCGCCC CTGTTGGTCA CGATGGCGGA


 


1051
AGCGCGTTTC ATCACCGGTT CCCAATCTGG GTCGGTCATG TCGGTAACCA


 


1101
GTACGTCGCC GGCTTCGACG GAATCCATCT CGGAAGCATC TTTAATCAGG


 


1151
CGTACCTTGC CCTGACCGAC TTTCTGACCG ATGGCGCGGC CTTCGCACAA


 


1201
GACGGTTTTT TCGCCGTTGA TAGAAAAGCG GCGCAGGTTG CGGCTGCCTT


 


1251
CTTCCTGGGA TTTGACGGTT TCGGGACGGG CTTGCAGGAT GTAGAGTTTG


 


1301
CCGTCCAAGC CGTCGCGTCC CCATTCGATG TCCATCGGGC GGCCGTAGTG


 


1351
TTTTTCGATG GTCAGTGCGT AATGCGCCAA CTCGGTGATT TCTTCGTCGG


 


1401
TAATGGAGAA GCGGTTGCGG TCTTCTTCGG GGACATCGAC GTTGGTTACC


 


1451
GATTTGCCGG CTTCTGCTTT GTCGGTAAAA ATCATTTTGA TGTGTTTTGA


 


1501
GCCCATGGTT TTGCGCAGGA TGGCAGGTTT GCCTGCTTTC AGCGTGGGTT


 


1551
TGAACACATA GAATTCGTCG GGATTGACTG CGCCTTGTAC GACGTTTTCG


 


1601
CCCAGACCGT AGGATGAAGT GACAAAGACG ACTTGGTCGT AACCGGATTC


 


1651
GGTATCGAGG GTGAACATCA C






This corresponds to the amino acid sequence <SEQ ID 1336; ORF 501.a>:










a501.pep




1
MVGRALTADA DIFVLLAAGG DGKVQHHFDG RVAFVKRFGY QAAVAVETEG


 


51
QLGHVVRADG EAVEVLQELF RQYRVARQLA HHNQAQAVFA AFQAVFFQGF


 


101
DNGFGFAQSA DERNHDFNVG QPHFIADAFQ GFAFQGETVF EVVGDITRRT


 


151
TEAQHRVFFM RFVYVAADQV GVFVGFEVGH TDDGFTRINR CGQCRHAFGD


 


201
FIDVEVDRGR VTGDTAGNFR F*FVVLFVKF QQGFGVDTDL AVDDKFHTRQ


 


251
ADAFAGQVGE AECEFGIADV HHDFYRCFRH VVQSNIGNLY VQQAGVDEAG


 


301
IAFGTGYGNF LTVFQQFGCI AAADNGRNTQ FARDDGGVAG TSAPVGHDGG


 


351
SAFHHRFPIW VGHVGNQYVA GFDGIHLGSI FNQAYLALTD FLTDGAAFAQ


 


401
DGFFAVDRKA AQVAAAFFLG FDGFGTGLQD VEFAVQAVAS PFDVHRAAVV


 


451
FFDGQCVMRQ LGDFFVGNGE AVAVFFGDID VGYRFAGFCF VGKNHFDVF*


 


501
AHGFAQDGRF ACFQRGFEHI EFVGIDCALY DVFAQTVG*S DKDDLVVTGF


 


551
GIEGEHH






m501/a501 90.3% identity in 557 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1337>:










g502.seq




1
atgatgaaac cgcacaacct gttccaattc ctcgccgttt gctccctgac


 


51
cgtcgccgtc gcttccgcac aggcgggcgc ggtggacgcg ctcaagcaat


 


101
tcaacaacga tgccgacggt atcagcggca gcttcaccca aaccgtccaa


 


151
agcaaaaaga aaacccaaac cgcgcacggc acgttcaaaa tcctgcgccc


 


201
gggcctcttc aaatgggaat acactttgcc ctacagacag actattgtcg


 


251
gcgacggtca aaccgtttgg ctctacgatg ttgatttggc acaagtgacc


 


301
aagtcgtccc aagaccaggc catcggcggc agccccgccg ccatcctgtc


 


351
gaacaaaacc gccctcgaaa gcagttacac gctgaaagag gacggttcgt


 


401
ccaacggcat cgattatgtg cggggcaacg cccaaacgca acaacgccgg


 


451
ctaccaatac atccgcatcg gcttcaaagg cggcaacctc gccgccatgc


 


501
agcttaa






This corresponds to the amino acid sequence <SEQ ID 1338; ORF 502.ng>:










g502.pep




1
MMKPHNLFQF LAVCSLTVAV ASAQAGAVDA LKQFNNDADG ISGSFTQTVQ


 


51
SKKKTQTAHG TFKILRPGLF KWEYTLPYRQ TIVGDGQTVW LYDVDLAQVT


 


101
KSSQDQAIGG SPAAILSNKT ALESSYTLKE DGSSNGIDYV RGNAQTQQRR


 


151
LPIHPHRLQR RQPRRHAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1339>:










m502.seq




1
atgatgaaac cgcacaacct gttccaattc ctcgccgttt gctccctgac


 


51
cgtcgccgtc gcttccgcac aggcgggcgc ggtagacgcg cttaagcaat


 


101
tcaacaacga tgccgacggt atcagcggca gcttcaccca amccgtccaa


 


151
wgcaaaaaga aaacccaaac cgcgcacggc acgttcaaaa tcctgcgacc


 


201
gggccttttc aaatgggaat acaccaaact t.acaggcaa accatcgtcg


 


251
gcgacggtca aacygtttgg ctmtacgatg tygatctggc acaagtgacc


 


301
aagtcgtccc aagaccaggc cataggcgsc agccccgccg ccatcctgtc


 


351
gaacaaarcc gccctcgaaa gcagctacac gctgaaagag gacggttcgt


 


401
ccaacggcat cgattatgtg ggcaacgccc aaacgcaaca acgccggcta


 


451
ccaatacatc cgcatcggct tcaaaggcgg caacctcgcc gccatgcagc


 


501
tyaa






This corresponds to the amino acid sequence <SEQ ID 1340; ORF 502.ng>:










m502.pep




1
MMKPHNLFQF LAVCSLTVAV ASAQAGAVDA LKQFNNDADG ISGSFTQXVQ


 


51
XKKKTQTAHG TFKILRPGLF KWEYTKLYRQ TIVGDGQTVW LYDVDLAQVT


 


101
KSSQDQAIGX SPAAILSNKX ALESSYTLKE DGSSNGIDYV GNAQTQQRRL


 


151
PIHPHRLQRR QPRRHAAX






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 502 shows 95.8% identity over a 168 aa overlap with a predicted ORF (ORF 502.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1341>:










a502.seq




1
ATGATGAAAC CGCACAACCT GTTCCAATTC CTCGCCGTTT GCTCCCTGAC


 


51
CGTCTCCGTC GCTTCCGCAC AGGCGGGCGC GGTGGACGCG CTCAAGCAAT


 


101
TCAACAACGA TGCCGACGGT ATCAGCGGCA GCTTCACCCA AACCGTCCAA


 


151
AGCAAAAAGA AAACCCAAAC CGCGCACGGC ACGTTCAAAA TCCTGCGCCC


 


201
GGGCCTCTTT AAATGGGAAT ACACTTCGCC TTACAAACAG ACTATTGTCG


 


251
GCGACGGTCA AACCGTTTGG CTCTACGATG TCGATTTGGC ACAAGTGACC


 


301
AAGTCGTCCC AAGACCAGGC CATAGGCGGC AGCCCCGCCG CCATCCTGTC


 


351
GAACAAAACC GCCCTCGAAA GCAGCTACAC GCTGAAAGAG GACGGTTCGT


 


401
CCAACGGCAT CGATTATGTG GGCAACGCCC AAACGCAACA ACGCCGGCTA


 


451
CCAATACATC CGCATCGGCT TCAAAGGCGG CAACCTCGCC GCCATGCAGC


 


501
TTAA






This corresponds to the amino acid sequence <SEQ ID 1342; 502 217.a>:










a502.pep




1
MMKPHNLFQF LAVCSLTVSV ASAQAGAVDA LKQFNNDADG ISGSFTQTVQ


 


51
SKKKTQTAHG TFKILRPGLF KWEYTSPYKQ TIVGDGQTVW LYDVDLAQVT


 


101
KSSQDQAIGG SPAAILSNKT ALESSYTLKE DGSSNGIDYV GNAQTQQRRL


 


151
PIHPHRLQRR QPRRHAA*






m502/a502 95.2% identity in 167 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1343>:










g502-1.seq




1
ATGatGAAAc cgcaCaacct gttccaaTTc CTCGCCGTTT GCTCCCTGAC


 


51
CGTCGCCGTC GCTTCCGCAC AGGCGGGCGC GGTGGACGCG CTCAAGCAAT


 


101
TCAACAACGA TGCCGACGGT ATCAGCGGCA GCTTCACCCA AACCGTCCAA


 


151
AGCAAAAAGA AAACCCAAAC CGCGCACGGC ACGTTCAAAA TCCTGCGCCC


 


201
GGGCCTCTTC AAATGGGAAT ACACTTTGCC CTACAGACAG ACTATTGTCG


 


251
GCGACGGTCA AACCGTTTGG CTCTACGATG TTGATTTGGC ACAAGTGACC


 


301
AAGTCGTCCC AAGACCAGGC CATCGGCGGC AGCCCCGCCG CCATCCTGTC


 


351
GAACAAAACC GCCCTCGAAA GCAGTTACAC GCTGAAAGAG GACGGTTCGT


 


401
CCAACGGCAT CGATTATGTG CGGGCAACGC CCAAACGCAA CAACGCCGGC


 


451
TACCAATACA TCCGCATCGG CTTCAAAGGC GGCAACCTCG CCGCCATGCA


 


501
GCTTAAAGAC AGCTTCGGCA ACCAAACCTC CATCAGTTTC GGCGGTTTGA


 


551
ATACCAATCC CCAACTCTCG CGCGGCGCGT TCAAGTTTAC CCCGCCCAAA


 


601
GGCGTGGACG TGTTGAGCAA CTGA






This corresponds to the amino acid sequence <SEQ ID 1344; ORF 502-1.ng>:










g502-1.pep




1
MMKPHNLFQF LAVCSLTVAV ASAQAGAVDA LKQFNNDADG ISGSFTQTVQ


 


51
SKKKTQTAHG TFKILRPGLF KWEYTLPYRQ TIVGDGQTVW LYDVDLAQVT


 


101
KSSQDQAIGG SPAAILSNKT ALESSYTLKE DGSSNGIDYV RATPKRNNAG


 


151
YQYIRIGFKG GNLAAMQLKD SFGNQTSISF GGLNTNPQLS RGAFKFTPPK


 


201
GVDVLSN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1345>:










m502-1.seq




1
ATGATGAAAC CGCACAACCT GTTCCAATTC CTCGCCGTTT GCTCCCTGAC


 


51
CGTCGCCGTC GCTTCCGCAC AGGCGGGCGC GGTAGACGCG CTTAAGCAAT


 


101
TCAACAACGA TGCCGACGGT ATCAGCGGCA GCTTCACCCA AACCGTCCAA


 


151
AGCAAAAAGA AAACCCAAAC CGCGCACGGC ACGTTCAAAA TCCTGCGACC


 


201
GGGCCTTTTC AAATGGGAAT ACACCAAACC TTACAGGCAA ACCATCGTCG


 


251
GCGACGGTCA AACCGTTTGG CTCTACGATG TTGATCTGGC ACAAGTGACC


 


301
AAGTCGTCCC AAGACCAGGC CATAGGCGGC AGCCCCGCCG CCATCCTGTC


 


351
GAACAAAACC GCCCTCGAAA GCAGCTACAC GCTGAAAGAG GACGGTTCGT


 


401
CCAACGGCAT CGATTATGTG CTGGCAACGC CCAAACGCAA CAACGCCGGC


 


451
TACCAATACA TCCGCATCGG CTTCAAAGGC GGCAACCTCG CCGCCATGCA


 


501
GCTTAAAGAC AGCTTCGGCA ACCAAACCTC CATCAGTTTC GGCGGTTTGA


 


551
ATACCAATCC CCAACTCTCG CGCGGCGCGT TCAAGTTTAC CCCGCCCAAA


 


601
GGCGTGGACG TGTTGAGCAA CTGA






This corresponds to the amino acid sequence <SEQ ID 1346; ORF 502-1>:










m502-1.pep




1
MMKPHNLFQF LAVCSLTVAV ASAQAGAVDA LKQFNNDADG ISGSFTQTVQ


 


51
SKKKTQTAHG TFKILRPGLF KWEYTKPYRQ TIVGDGQTVW LYDVDLAQVT


 


101
KSSQDQAIGG SPAAILSNKT ALESSYTLKE DGSSNGIDYV LATPKRNNAG


 


151
YQYIRIGFKG GNLAAMQLKD SFGNQTSISF GGLNTNPQLS RGAFKFTPPK


 


201
GVDVLSN*






m502-1/g502-1 99.0% identity in 207 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1347>:










a502-1.seq




1
ATGATGAAAC CGCACAACCT GTTCCAATTC CTCGCCGTTT GCTCCCTGAC


 


51
CGTCTCCGTC GCTTCCGCAC AGGCGGGCGC GGTGGACGCG CTCAAGCAAT


 


101
TCAACAACGA TGCCGACGGT ATCAGCGGCA GCTTCACCCA AACCGTCCAA


 


151
AGCAAAAAGA AAACCCAAAC CGCGCACGGC ACGTTCAAAA TCCTGCGCCC


 


201
GGGCCTCTTT AAATGGGAAT ACACTTCGCC TTACAAACAG ACTATTGTCG


 


251
GCGACGGTCA AACCGTTTGG CTCTACGATG TCGATTTGGC ACAAGTGACC


 


301
AAGTCGTCCC AAGACCAGGC CATAGGCGGC AGCCCCGCCG CCATCCTGTC


 


351
GAACAAAACC GCCCTCGAAA GCAGCTACAC GCTGAAAGAG GACGGTTCGT


 


401
CCAACGGCAT CGATTATGTG CTGGCAACGC CCAAACGCAA CAACGCCGGC


 


451
TACCAATACA TCCGCATCGG CTTCAAAGGC GGCAACCTCG CCGCCATGCA


 


501
GCTTAAAGAC AGCTTCGGCA ATCAAACCTC CATCAGTTTC GGCGGTTTGA


 


551
ATACCAATCC CCAACTCTCG CGCGGCGCGT TCAAGTTTAC CCCGCCCAAA


 


601
GGCGTGGACG TGTTGAGCAA CTGA






This corresponds to the amino acid sequence <SEQ ID 1348; ORF 502-1.a>:










a502-1.pep




1
MMKPHNLFQF LAVCSLTVSV ASAQAGAVDA LKQFNNDADG ISGSFTQTVQ


 


51
SKKKTQTAHG TFKILRPGLF KWEYTSPYKQ TIVGDGQTVW LYDVDLAQVT


 


101
KSSQDQAIGG SPAAILSNKT ALESSYTLKE DGSSNGIDYV LATPKRNNAG


 


151
YQYIRIGFKG GNLAAMQLKD SFGNQTSISF GGLNTNPQLS RGAFKFTPPK


 


201
GVDVLSN*






a502-1/m502-1 98.6% identity in 207 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1349>:










g503.seq




1
atgtccgcgc cgtcggcatc ggtaatcatt ttgttccatg ccgcttcgat


 


51
ttcggcatcg agctgttcgg ggaagggcgt gtccaaaatc cattggcgga


 


101
tttctttgcc gacgcgtgcc agttcggaaa cgtcttcgac atccaatttt


 


151
gccagagcgg cggaaatgcg ttcgttcaga ccgttgtgtg cgagaaatgc


 


201
gcggtag






This corresponds to the amino acid sequence <SEQ ID 1350; ORF 503.ng>:










g503.pep




1
MSAPSASVII LFHAASISAS SCSGKGVSKI HWRISLPTRA SSETSSTSNF


 


51
ARAAEMRSFR PLCARNAR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1351>:










m503.seq




1
atgtccgcac cgccggcatc ggcaaccatt ttgttccatg ccgcttcgat


 


51
ttcggcatcg agctgttcgg ggaaaggcgt atccaaaatc cattggcgga


 


101
tttctttgcc gacgcgtgcc agttcggcaa cgtcttcgac atccaatttt


 


151
gccagtgcgg cggaaatgcg ttcgctcaga ccgttgtgtg cgaggaatgc


 


201
gcggtag






This corresponds to the amino acid sequence <SEQ ID 1352; ORF 503>:










m503.pep




1
MSAPPASATI LFHAASISAS SCSGKGVSKI HWRISLPTRA SSATSSTSNF


 


51
ASAAEMRSLR PLCARNAR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 503 shows 91.2% identity over a 68 aa overlap with a predicted ORF (ORF 503.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1353>:










a503.seq




1
ATGTCCGCGC CGCCGGCATC GGCAACCATT TTGTTCCATG CCGCTTCGAT


 


51
TTCGGCATCG AGCTGTTCGG GGAAGGGCGT GTCCAAAATC CATTGGCGGA


 


101
TTTCTTTGCC GACGCGTGCC AGTTCGGCAA CGTCTTCGAC ATCTAATTTT


 


151
GCCAGTGCGG CGGAAATGCG TTCGCTCAGA CCGTTGTGTG CGAGGAATGC


 


201
GCGGTAG






This corresponds to the amino acid sequence <SEQ ID 1354; ORF 503.a>:










a503.pep




1
MSAPPASATI LFHAASISAS SCSGKGVSKI HWRISLPTRA SSATSSTSNF


 


51
ASAAEMRSLR PLCARNAR*






m503/a503 100.0% identity in 68 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1355>:










g503-1.seq




1
ATGGCGCGGT CGTTGTACAG GGAGGCGAAA ACGTGGCGCA TCGCTTTTTT


 


51
AACGTTATCC AAGCCATTGA TATTCAGGAA GGTTTCCTGT TGGCCGGCAA


 


101
ATGATGCGTC GGGCAGGTCT TCGGCGGTTG CGGAAGAGCG TACGGCAACG


 


151
GAAATGTCCG CGCCGTCGGC ATCGGTAATC ATTTTGTTCC ATGCCGCTTC


 


201
GATTTCGGCA TCGAGCTGTT CGGGGAAGGG CGTGTCCAAA ATCCATTGGC


 


251
GGATTTCTTT GCCGACGCGT GCCAGTTCGG AAACGTCTTC GACATCCAAT


 


301
TTTGCCAGAG CGGCGGAAAT GCGTTCGTTC AGACCGTTGT GTGCGAGAAA


 


351
TGCGCGGTAG






This corresponds to the amino acid sequence <SEQ ID 1356; ORF 214.ng>:










g503-1.pep




1
MARSLYREAK TWRIAFLTLS KPLIFRKVSC WPANDASGRS SAVAEERTAT


 


51
EMSAPSASVI ILFHAASISA SSCSGKGVSK IHWRISLPTR ASSETSSTSN


 


101
FARAAEMRSF RPLCARNAR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1357>:










m503-1.seq




1
ATGGCACGGT CGTTATACAG GGAAGCGAAT ACATGGTGCA TCGCTTCTTT


 


51
AACGTTATCC AAGCCGTTGA TGTTCAAGAA GGTTTCCTGT TGTCCAGCGA


 


101
ATGATGCGTC CGGCAGGTCT TCGGCAGTTG CGGAAGAACG TACGGCAACG


 


151
GAAATGTCCG CACCGCCGGC ATCGGCAACC ATTTTGTTCC ATGCCGCTTC


 


201
GATTTCGGCA TCGAGCTGTT CGGGGAAAGG CGTATCCAAA ATCCATTGGC


 


251
GGATTTCTTT GCCGACGCGT GCCAGTTCGG CAACGTCTTC GACATCCAAT


 


301
TTTGCCAGTG CGGCGGAAAT GCGTTCGCTC AGACCGTTGT GTGCGAGGAA


 


351
TGCGCGGTAG






This corresponds to the amino acid sequence <SEQ ID 1358; ORF 503-1>:










m503-1.pep




1
MARSLYREAN TWCIASLTLS KPLMFKKVSC CPANDASGRS SAVAEERTAT


 


51
EMSAPPASAT ILFHAASISA SSCSGKGVSK IHWRISLPTR ASSATSSTSN


 


101
FASAAEMRSL RPLCARNAR*






g503-1/m503-1 89.9% identity in 119 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1359>:










a503-1.seq




1
ATGGCGCGGT CGTTGTACAG GGAGGCGAAT ACATGGCGCA TCGCTTCTTT


 


51
AACGTTTTCC AAGCCGTTGA TATTCAGGAA GGTTTCCTGT TGGCCGGCAA


 


101
ATGATGCGTC GGGCAGGTCT TCGGCGGTTG CGGAAGAGCG TACGGCAACG


 


151
GAAATGTCCG CGCCGCCGGC ATCGGCAACC ATTTTGTTCC ATGCCGCTTC


 


201
GATTTCGGCA TCGAGCTGTT CGGGGAAGGG CGTGTCCAAA ATCCATTGGC


 


251
GGATTTCTTT GCCGACGCGT GCCAGTTCGG CAACGTCTTC GACATCTAAT


 


301
TTTGCCAGTG CGGCGGAAAT GCGTTCGCTC AGACCGTTGT GTGCGAGGAA


 


351
TGCGCGGTAG






This corresponds to the amino acid sequence <SEQ ID 1360; ORF 503-1.a>:










a503-1.pep




1
MARSLYREAN TWRIASLTFS KPLIFRKVSC WPANDASGRS SAVAEERTAT


 


51
EMSAPPASAT ILFHAASISA SSCSGKGVSK IHWRISLPTR ASSATSSTSN


 


101
FASAAEMRSL RPLCARNAR*






a503-1/m503-1 95.8% identity in 119 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1361>:










g504.seq




1
atgttggttc aggacttgcc ttttgaagtc aaactgaaaa aattccatat


 


51
cgatttttac aatacgggta tgccgcgcga ttttgccagc gatattgaag


 


101
taacggacaa ggcaaccggt gagaaactcg agcgcaccat ccgcgtgaac


 


151
catcctttga ccttgcacgg catcacgatt tatcaggcga gttttgccga


 


201
cggcggttcg gatttgacat tcaaggcgtg gaatttgagg gatgcttcgc


 


251
gcgaacctgt cgtgttgaag gcaacctcca tacaccagtt tccgttggaa


 


301
atcggcaaac acaaatatcg tcttgagttc gatcagttca cttctatgaa


 


351
tgtggaggac atgagcgagg gtgcggaacg ggaaaaaagc ctgaaatcca


 


401
ctctgaacga tgtccgcgcc gttactcagg aaggtaaaaa atacaccaat


 


451
atcggccctt ccatcgtgta ccgcatccgt gatgcggcag ggcaggcggt


 


501
cgaatataaa aactatatgc tgccgatttt gcaggacaaa gattattttt


 


551
ggctgaccgg cacgcgcagc ggcttgcagc agcaataccg ctggctgcgt


 


601
atccccttgg acaagcagtt gaaagcggac acctttatgg cattgcgtga


 


651
gtttttgaaa gatggggaag ggcgcaaacg tctggttgcc gacgcaacca


 


701
aagacgcacc tgccgaaatc cgcgaacaat tcatgctggc tgcggaaaac


 


751
acgctgaata tctttgcgca aaaaggctat ttgggattgg acgaatttat


 


801
tacgtccaat atcccgaaag ggcagcagga taagatgcag ggctatttct


 


851
acgaaatgct ttacggcgtg atgaacgctg ctttggatga aaccatacgc


 


901
cggtacggct tgcccgaatg gcagcaggat gaagcgcgga accgtttcct


 


951
gctgcacagt atggatgcct atacggggct gacggaatat cccgcgccta


 


1001
tgctgctcca gcttgacggg ttttccgagg tgcgttcctc aggtttgcag


 


1051
atgacccgtt cgccgggtgc gcttttggtc tatctcggct cggtattgtt


 


1101
ggttttgggt acagtattta tgttttatgt gcccaaaaaa cgggcgtggg


 


1151
tattgttttc aaacdgcaaa atccgttttg ctatgtcttc ggcccgcagc


 


1201
gaacgggatt tgcagaagga atttccaaaa cacgtcgaga gcctgcaacg


 


1251
gctcggcaag gacttgaatc atgactga






This corresponds to the amino acid sequence <SEQ ID 1362; ORF 504.ng>:










g504.pep




1
MLVQDLPFEV KLKKFHIDFY NTGMPRDFAS DIEVTDKATG EKLERTIRVN


 


51
HPLTLHGITI YQASFADGGS DLTFKAWNLR DASREPVVLK ATSIHQFPLE


 


101
IGKHKYRLEF DQFTSMNVED MSEGAEREKS LKSTLNDVRA VTQEGKKYTN


 


151
IGPSIVYRIR DAAGQAVEYK NYMLPILQDK DYFWLTGTRS GLQQQYRWLR


 


201
IPLDKQLKAD TFMALREFLK DGEGRKRLVA DATKDAPAEI REQFMLAAEN


 


251
TLNIFAQKGY LGLDEFITSN IPKGQQDKMQ GYFYEMLYGV MNAALDETIR


 


301
RYGLPEWQQD EARNRFLLHS MDAYTGLTEY PAPMLLQLDG FSEVRSSGLQ


 


351
MTRSPGALLV YLGSVLLVLG TVFMFYVPKK RAWVLFSNKI RFAMSSARSE


 


401
RDLQKEFPKH VESLQRLGKD LNHD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1363>:










m504.seq..




1
atattggttc aggacttgcc ttttgaagtc aaactgaaaa aattccatat


 


51
cgatttttac aatacgggta tgccgcgtga tttcgccagc gatattgaag


 


101
tgacggacaa ggcaaccggt gagaaactcg agcgcaccat ccgcgtgaac


 


151
catcctttga ccttgcacgg catcacgatt tatcaggcga gttttgccga


 


201
cggcggttcg gatttgacat tcaaggcgtg gaatttgggt gatgcttcgc


 


251
gcgagcctgt cgtgttgaag gcaacatcca tacaccagtt tccgttggaa


 


301
attggcaaac acaaatatcg tcttgagttc gatcagttca cttctatgaa


 


351
tgtggaggac atgagcgagg gcgcggaacg ggaaaaaagc ctgaaatcca


 


401
cgctgmmcga tgtccgcgcc gttactcagg aaggtaaaaa atacaccaat


 


451
atcggccctt ccattgttta ccgtatccgt gatgcggcag ggcaggcggt


 


501
cgaatataaa aactatatgc tgccggtttt gcaggaacag gattattttt


 


551
ggattaccgg cacgcgcagc ggcttgcagc agcaataccg ctggctgcgt


 


601
atccccttgg acaagcagtt gaaagcggac acctttatgg cattgcgtga


 


651
gtttttgaaa gatggggaag ggcgcaaacg tctggttgcc gacgcaacca


 


701
aaggcgcacc tgccgaaatc cgcgaacaat tcatgctggc tgcggaaaac


 


751
acgctgaaca tctttgcaca aaaaggctat ttgggattgg acgaatttat


 


801
tacgtccaat atcccgaaag agcagcagga taagatgcag ggctatttct


 


851
acgaaatgct ttacggcgtg atgaacgctg ctttggatga aaccatacgc


 


901
cggtacggct tgcccgaatg gcagcaggat gaagcgcgga atcgtttcct


 


951
gctgcacagt atggatgcgt acacgggttt gaccgaatat cccgcgccta


 


1001
tgctgctgca acttgatggg ttttccgagg tgcgttcgtc gggtttgcag


 


1051
atgacccgtt ccccgggtgc gcttttggtc tatctcggct cggtgctgtt


 


1101
ggtattgggt acggtattga tgttttatgt gcgcgaaaaa cgggcgtggg


 


1151
tattgttttc agacggcaaa atccgttttg ccatgtcttc ggcccgcagc


 


1201
gaacgggatt tgcagaagga atttccaaaa cacgtcgaga gtctgcaacg


 


1251
gctcggcaag gacttgaatc atga






This corresponds to the amino acid sequence <SEQ ID 1364; ORF 504>:










m504.pep..




1
ILVQDLPFEV KLKKFHIDFY NTGMPRDFAS DIEVTDKATG EKLERTIRVN


 


51
HPLTLHGITI YQASFADGGS DLTFKAWNLG DASREPVVLK ATSIHQFPLE


 


101
IGKHKYRLEF DQFTSMNVED MSEGAEREKS LKSTLXDVRA VTQEGKKYTN


 


151
IGPSIVYRIR DAAGQAVEYK NYMLPVLQEQ DYFWITGTRS GLQQQYRWLR


 


201
IPLDKQLKAD TFMALREFLK DGEGRKRLVA DATKGAPAEI REQFMLAAEN


 


251
TLNIFAQKGY LGLDEFITSN IPKEQQDKMQ GYFYEMLYGV MNAALDETIR


 


301
RYGLPEWQQD EARNRFLLHS MDAYTGLTEY PAPMLLQLDG FSEVRSSGLQ


 


351
MTRSPGALLV YLGSVLLVLG TVLMFYVREK RAWVLFSDGK IRFAMSSARS


 


401
ERDLQKEFPK HVESLQRLGK DLNHD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 504 shows 96.7% identity over a 425 aa overlap with a predicted ORF (ORF 504.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1365>:










a504.seq




1
ATATTGGTTC AGGACTTGCC TTTTGAAGTC AAACTGAAAA AATTCCATAT


 


51
CGATTTTTAC AATACGGGTA TGCCGCGCGA TTTTGCCAGT GATATTGAAG


 


101
TAACGGATAA GGCAACCGGT GAGAAACTCG AGCGCACCAT CCGCGTGAAC


 


151
CATCCTTTGA CCTTGCACGG CATCACGATT TATCAGGCGA GTTTTGCCGA


 


201
CGGCGGTTCG GATTTGACAT TCAAGGCGTG GAATTTGGGT GATGCTTCGC


 


251
GCGAGCCTGT CGTGTTGAAG GCAACATCCA TACACCAGTT TCCGTTGGAA


 


301
ATTGGCAAAC ACAAATATCG TCTTGAGTTC GATCAGTTTA CTTCTATGAA


 


351
TGTGGAGGAC ATGAGCGAGG GCGCGGAACG GGAAAAAAGC CTGAAATCCA


 


401
CGCTGAACGA TGTCCGCGCC GTTACTCAGG AAGGTAAAAA ATACACCAAT


 


451
ATCGGCCCTT CCATTGTTTA CCGTATCCGT GATGCGGCAG GGCAGGCGGT


 


501
CGAATATAAA AACTATATGC TGCCGGTTTT GCAGGAACAG GATTATTTTT


 


551
GGATTACCGG CACGCGCAGC GGCTTGCAGC AGCAATACCG CTGGCTGCGT


 


601
ATCCCCTTGG ACAAGCAGTT GAAAGCGGAC ACCTTTATGG CATTGCGTGA


 


651
GTTTTTGAAA GATGGGGAAG GGCGCAAACG TCTGGTTGCC GACGCAACCA


 


701
AAGGCGCACC TGCCGAAATC CGCGAACAAT TCATGCTGGC TGCGGAAAAC


 


751
ACGCTGAACA TCTTTGCACA AAAAGGCTAT TTGGGATTGG ACGAATTTAT


 


801
TACGTCCAAT ATCCCGAAAG AGCAGCAGGA TAAGATGCAG GGCTATTTCT


 


851
ACGAAATGCT TTACGGCGTG ATGAACGCTG CTTTGGATGA AACCATACGC


 


901
CGGTACGGCT TGCCCGAATG GCAGCAGGAT GAAGCGCGGA ATCGTTTCCT


 


951
GCTGCACAGT ATGGATGCGT ACACGGGTTT GACCGAATAT CCCGCGCCTA


 


1001
TGCTGCTGCA ACTTGATGGG TTTTCCGAGG TGCGTTCGTC GGGTTTGCAG


 


1051
ATGACCCGTT CCCCGGGTGC GCTTTTGGTC TATCTCGGCT CGGTGCTGTT


 


1101
GGTATTGGGT ACGGTATTGA TGTTTTATGT GCGCGAAAAA CGGGCGTGGG


 


1151
TATTGTTTTC AGACGGCAAA ATCCGTTTTG CCATGTCTTC GGCTTGCAGC


 


1201
GAACGGGATT TGCAGAAGGA ATTTCCAAAA CACGTCGAGA GTCTGCAACG


 


1251
GCTCGGCAAG GACTTGAATC ATGACTGA






This corresponds to the amino acid sequence <SEQ ID 1366; ORF 504.a>:










a504.pep




1
ILVQDLPFEV KLKKFHIDFY NTGMPRDFAS DIEVTDKATG EKLERTIRVN


 


51
HPLTLHGITI YQASFADGGS DLTFKAWNLG DASREPVVLK ATSIHQFPLE


 


101
IGKHKYRLEF DQFTSMNVED MSEGAEREKS LKSTLNDVRA VTQEGKKYTN


 


151
IGPSIVYRIR DAAGQAVEYK NYMLPVLQEQ DYFWITGTRS GLQQQYRWLR


 


201
IPLDKQLKAD TFMALREFLK DGEGRKRLVA DATKGAPAEI REQFMLAAEN


 


251
TLNIFAQKGY LGLDEFITSN IPKEQQDKMQ GYFYEMLYGV MNAALDETIR


 


301
RYGLPEWQQD EARNRFLLHS MDAYTGLTEY PAPMLLQLDG FSEVRSSGLQ


 


351
MTRSPGALLV YLGSVLLVLG TVLMFYVREK RAWVLFSDGK IRFAMSSARS


 


401
ERDLQKEFPK HVESLQRLGK DLNHD*






m504/a504 99.8% identity in 425 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1367>:










g505.seq




1
atgtttcgtt tacaattcag gctgtttccc cctttgcgaa ccgccatgca


 


51
catcctgttg accgccctgc tcaaatgcct ctccctgctg tcgctttcct


 


101
gtctgcacac gctgggaaac cggctcggac atctggcgtt ttacctttta


 


151
aaggaagacc gcgcgcgcat cgtcgccaat atgcggcagg cgggtttgaa


 


201
ccccgacacg cagacggtca aagccgtttt tgcggaaacg gcaaaatgcg


 


251
gtttggaact tgcccccgcg tttttcaaaa aaccggaaga catcgaaaca


 


301
atgttcaaag cggtacacgg ctgggaacac gtgcagcagg ctttggacaa


 


351
gggcgaaggg ctgctgttca tcacgccgca catcggcagc tacgatttgg


 


401
gcggacgcta catcagccag cagcttccgt tccacctgac cgccatgtac


 


451
aagccgccga aaatcaaagc gatagacaaa atcatgcagg cgggcagggt


 


501
gcgcggcaaa ggcaaaaccg cgcccaccgg catacaaggg gtcaaacaaa


 


551
tcatcaaggc cctgcgcgcg ggcgaggcaa ccatcatcct gcccgaccac


 


601
gtcccttctc cgcaggaagg cggcggcgtg tgggcggatt ttttcggcaa


 


651
acctgcatac accatgacac tggcggcaaa attggcacac gtcaaaggcg


 


701
tgaaaaccct gtttttctgc tgcgaacgcc tgcccgacgg acaaggcttc


 


751
gtgttgcaca tccgccccgt ccaaggggaa ttgaacggca acaaagccca


 


801
cgatgccgcc gtgttcaacc gcaataccga atattggata cgccgttttc


 


851
cgacgcagta tctgtttatg tacaaccgct ataaaacgcc gtaa






This corresponds to the amino acid sequence <SEQ ID 1368; ORF 505.ng>:










g505.pep




1
MFRLQFRLFP PLRTAMHILL TALLKCLSLL SLSCLHTLGN RLGHLAFYLL


 


51
KEDRARIVAN MRQAGLNPDT QTVKAVFAET AKCGLELAPA FFKKPEDIET


 


101
MFKAVHGWEH VQQALDKGEG LLFITPHIGS YDLGGRYISQ QLPFHLTAMY


 


151
KPPKIKAIDK IMQAGRVRGK GKTAPTGIQG VKQIIKALRA GEATIILPDH


 


201
VPSPQEGGGV WADFFGKPAY TMTLAAKLAH VKGVKTLFFC CERLPDGQGF


 


251
VLHIRPVQGE LNGNKAHDAA VFNRNTEYWI RRFPTQYLFM YNRYKTP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1369>:









m505.seq (partial)










1
GGCATGTTTC GTTTACAATT CAGGCTGTTT CCCCCTTTGC GAACCGCCAT



 


51
GCACATCCTG TTGACCGCCC TGCTCAAATG CCTCTCCCTG CTGCCGCTTT


 


101
CCTGTCTGCA CACGCTGGGA AACCGGCTCG GACATCTGGC GTTTTACCTT


 


151
TTAAAGGAAG ACCGCGCGCG CATCGTCGCC AATATGCGGC AGGCGGGTTT


 


201
GAACCCCGAC CCCAAAACGG TCAAAGCCGT TTTTGCGGAA ACGGCAAAAG


 


251
GCGGTTTGGA ACTTGCCCCC GCGTTTTTCA GAAAACCGGA AGACATAGAA


 


301
ACAATGTTCA AAGCGGTACA CGGCTGGGAA CATGTGCAGC AGGCTTTGGA


 


351
CAAACACGAA GGGCTGCTAT TCATCACGCC GCACATCGGC AGCTACGATT


 


401
TGGGCGGACG CTACATCAGC CAGCAGCTTC CGTTCCCGCT GACCGCCATG


 


451
TACAAACCGC CGAAAATCAA AGCGATAGAC AAAATCATGC AGGCGGGCAG


 


501
GGTTCGCGGC AAAGGAAAAA CCGCGCCTAC CAGCATACAA GGGGTCAAAC


 


551
AAATCATCAA AGCCCTGCGT TCGGGCGAgC AACCATCGTC CTGCCCGACC


 


601
ACGTCCCCTC CCCTCAAGAA GGCGGGGAAG GCGTATGGGT GGATTTCTTC


 


651
GGCAAACCTG CCTATACCAT GACGCTGGCG GCAArATTGG CACACGTCAA


 


701
AGGCGTGAAA ACCCTGTTTT TCTGCTGCGA ACGCCTGCCT GGCGGACAAG


 


751
GTTTCGATTT GCACATCCGC CCCGTCCAAG GGGAATTGAA CGGCGACAAA


 


801
GCCCATGATG CCGCCGTGTT CAACCGCAAT GCCGAATATT GGATACGCCG


 


851
TTTTCCGACG CAtATC....






This corresponds to the amino acid sequence <SEQ ID 1370; ORF 505>:









m505.pep (partial)










1
MFRLQFRLFP PLRTAMHILL TALLKCLSLL PLSCLHTLGN RLGHLAFYLL



 


51
KEDRARIVAN MRQAGLNPDP KTVKAVFAET AKGGLELAPA FFRKPEDIET


 


101
MFKAVHGWEH VQQALDKHEG LLFITPHIGS YDLGGRYISQ QLPFPLTAMY


 


151
KPPKIKAIDK IMQAGRVRGK GKTAPTSIQG VKQIIKALRS GEATIVLPDH


 


201
VPSPQEGGEG VWVDFFGKPA YTMTLAAXLA HVKGVKTLFF CCERLPGGQG


 


251
FDLHIRPVQG ELNGDKAHDA AVFNRNAEYW IRRFPTHI...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 505 shows 93.7% identity over a 287 aa overlap with a predicted ORF (ORF 505.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1371>:










a505.seq




1
ATGTTTCGTT TACAATTCAG GCTGTTTCCC CCTTTGCGAA CCGCCATGCA


 


51
CATCCTGTTG ACCGCCCTGC TCAAATGCCT CTCCCTGCTG CCGCTTTCCT


 


101
GTCTGCACAC GCTGGGAAAC CGGCTCGGAC ATCTGGCGTT TTACCTTTTA


 


151
AAGGAAGACC GCGCGCGCAT CGTCGCCAAT ATGCGTCAGG CAGGCATGAA


 


201
TCCCGACCCC AAAACGGTCA AAGCCGTTTT TGCGGAAACG GCAAAAGGCG


 


251
GTTTGGAACT TGCCCCCGCG TTTTTCAGAA AACCGGAAGA CATAGAAACA


 


301
ATGTTCAAAG CGGTACACGG CTGGGAACAT GTGCAGCAGG CTTTGGACAA


 


351
ACACGAAGGG CTGCTATTCA TCACGCCGCA CATCGGCAGC TACGATTTGG


 


401
GCGGACGCTA CATCAGCCAG CAGCTTCCGT TCCCGCTGAC CGCCATGTAC


 


451
AAACCGCCGA AAATCAAAGC GATAGACAAA ATCATGCAGG CGGGCAGGGT


 


501
TCGCGGCAAA GGAAAAACCG CGCCTACCAG CATACAAGGG GTCAAACAAA


 


551
TCATCAAAGC CCTGCGTTCG GGCGAAGCAA CCATCGTCCT GCCCGACCAC


 


601
GTCCCCTCCC CTCAAGAAGG CGGGGAAGGC GTATGGGTGG ATTTCTTCGG


 


651
CAAACCTGCC TATACCATGA CGCTGGCGGC AAAATTGGCA CACGTCAAAG


 


701
GCGTGAAAAC CCTGTTTTTC TGCTGCGAAC GCCTGCCTGG CGGACAAGGT


 


751
TTCGATTTGC ACATCCGCCC CGTCCAAGGG GAATTGAACG GCGACAAAGC


 


801
CCATGATGCC GCCGTGTTCA ACCGCAATGC CGAATATTGG ATACGCCGTT


 


851
TTCCGACGCA GTATCTGTTT ATGTACAACC GCTACAAAAT GCCGTAA






This corresponds to the amino acid sequence <SEQ ID 1372; ORF 505.a>:










a505.pep




1
MFRLQFRLFP PLRTAMHILL TALLKCLSLL PLSCLHTLGN RLGHLAFYLL


 


51
KEDRARIVAN MRQAGMNPDP KTVKAVFAET AKGGLELAPA FFRKPEDIET


 


101
MFKAVHGWEH VQQALDKHEG LLFITPHIGS YDLGGRYISQ QLPFPLTAMY


 


151
KPPKIKAIDK IMQAGRVRGK GKTAPTSIQG VKQIIKALRS GEATIVLPDH


 


201
VPSPQEGGEG VWVDFFGKPA YTMTLAAKLA HVKGVKTLFF CCERLPGGQG


 


251
FDLHIRPVQG ELNGDKAHDA AVFNRNAEYW IRRFPTQYLF MYNRYKMP*






m505/a505 99.0% identity in 287 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1373>:










m505-1.seq




1
ATGTTTCGTT TACAATTCAG GCTGTTTCCC CCTTTGCGAA CCGCCATGCA


 


51
CATCCTGTTG ACCGCCCTGC TCAAATGCCT CTCCCTGCTG CCGCTTTCCT


 


101
GTCTGCACAC GCTGGGAAAC CGGCTCGGAC ATCTGGCGTT TTACCTTTTA


 


151
AAGGAAGACC GCGCGCGCAT CGTCGCCAAT ATGCGGCAGG CGGGTTTGAA


 


201
CCCCGACCCC AAAACGGTCA AAGCCGTTTT TGCGGAAACG GCAAAAGGCG


 


251
GTTTGGAACT TGCCCCCGCG TTTTTCAGAA AACCGGAAGA CATAGAAACA


 


301
ATGTTCAAAG CGGTACACGG CTGGGAACAT GTGCAGCAGG CTTTGGACAA


 


351
ACACGAAGGG CTGCTATTCA TCACGCCGCA CATCGGCAGC TACGATTTGG


 


401
GCGGACGCTA CATCAGCCAG CAGCTTCCGT TCCCGCTGAC CGCCATGTAC


 


451
AAACCGCCGA AAATCAAAGC GATAGACAAA ATCATGCAGG CGGGCAGGGT


 


501
TCGCGGCAAA GGAAAAACCG CGCCTACCAG CATACAAGGG GTCAAACAAA


 


551
TCATCAAAGC CCTGCGTTCG GGCGAAGCAA CCATCGTCCT GCCCGACCAC


 


601
GTCCCCTCCC CTCAAGAAGG CGGGGAAGGC GTATGGGTGG ATTTCTTCGG


 


651
CAAACCTGCC TATACCATGA CGCTGGCGGC AAAATTGGCA CACGTCAAAG


 


701
GCGTGAAAAC CCTGTTTTTC TGCTGCGAAC GCCTGCCTGG CGGACAAGGT


 


751
TTCGATTTGC ACATCCGCCC CGTCCAAGGG GAATTGAACG GCGACAAAGC


 


801
CCATGATGCC GCCGTGTTCA ACCGCAATGC CGAATATTGG ATACGCCGTT


 


851
TTCCGACGCA GTATCTGTTT ATGTACAACC GCTACAAAAT GCCGTAA






This corresponds to the amino acid sequence <SEQ ID 1374; ORF 505-1>:










m505-1.pep




1
MFRLQFRLFP PLRTAMHILL TALLKCLSLL PLSCLHTLGN RLGHLAFYLL


 


51
KEDRARIVAN MRQAGLNPDP KTVKAVFAET AKGGLELAPA FFRKPEDIET


 


101
MFKAVHGWEH VQQALDKHEG LLFITPHIGS YDLGGRYISQ QLPFPLTAMY


 


151
KPPKIKAIDK IMQAGRVRGK GKTAPTSIQG VKQIIKALRS GEATIVLPDH


 


201
VPSPQEGGEG VWVDFFGKPA YTMTLAAKLA HVKGVKTLFF CCERLPGGQG


 


251
FDLHIRPVQG ELNGDKAHDA AVFNRNAEYW IRRFPTQYLF MYNRYKMP*






m505-1/g505 94.3% identity in 298 aa overlap





m505-1/a505 99.7% identity in 298 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1375>:










g506.seq




1
ATGGCGGTAT TTGATGAAGT CGGGCGCATC GCCCATGGCT GCGGCGGTGT


 


51
TGTCAAACAA AGCCTGTTTC TGCGCGTCGT TCATCAGGTT GAACAAGGCG


 


101
CGCGGTTGGC TGAAGTAGTC GTCATCGTCT TGGCGGTAGT CCCAGTGTGC


 


151
CGCGTCGCCG TTGATTTTCA AAGGCGGTTC GGCGAAGTCG GGTTGTTGCT


 


201
GCCATTGGCC GAAGCTGTTG GGTTCGTAGT GCGGCAGGCT GCCGTAGTTG


 


251
CCGTCGGCGC GGCCTTGTCC GTCGCGCTGG TTGCTGTGAA CAGGGCAACG


 


301
CGGACGATTG ACGGGGATTT GGCGGAAGTT CACACCCAAG CGGTAACGTT


 


351
GCGCGTCGGC GTAATTGAAC AAACGGGCTT GCAACATTTT ATCCGGGCTC


 


401
GCGCCGATAC CGGGAACGAG GTTGCTCGGT GCGAAGGCGG ATTGTTCCAC


 


451
ATCGGCGAAG AAGTTTTCGG GATTGCGGTT CAACTCGAAT TTGCCGACTT


 


501
CAATCAGCGG ATAGTCTTTT TTCGGCCAAA CTTTGGTCAA GTCAAACGGA


 


551
TGATAAGGCA CTTTTTCGGC ATCGGCTTCA GGCATGACTT GGATGTACAT


 


601
CGTCCATTTC GGGAACTCGC CGCGCTCGAT GGCTTCGTAC AGGTCGCGCT


 


651
GATGGCTTTC GCGGTCGTCG GCGATGATTT TTGCAGCTTC TTCGTTGGTC


 


701
AGGTTTTTAA TCCCTTGCTG GCTGCGGAAA TGGAATTTCA CCCAAAAACG


 


751
TTCGCCCGCT TCGTTCCAGA AGCTGTAGGT ATGCGAACCG AAGCCGTGCA


 


801
TATGGCGGTA GCTGGCGGGA ATACCGCGGT CGCTCATCAC GATGGTAACT


 


851
TGGTGCAGGG CTTCGGGCAG CAGCGTCCAG AAGTCCCAGT TGTTTGTGGC


 


901
GGAACGCATA TTGGTGCGCG GATCGCGTTT GACGGCTTTG TTCAGGTCGG


 


951
GGAATTTGCG CGGGTCGCGC AGGAAGAACA CGGGCGTGTT GTTGCCGACC


 


1001
ACATCCCAGT TGCCTTCTTC GGTATAGAAT TTCAACGCAA AACCGCGGAT


 


1051
GTCGCGTTCC GCATCGGCTG CGCCGCGCTC GCCTGCCACG GTGGTGAAAC


 


1101
GGGCGAACAT CTCGGTTTTT TTGCCGACTT CGCTGAAAAT TTTGGCGCGG


 


1151
GTGTATTTGG TGATGTCGTG TGTTACGGTA AACGTACCGA ACGCGCCCGA


 


1201
ACCTTTGGCG TGCATACGGC GTTCGGGGAT GACTTCGCGC ACGAAGTCGG


 


1251
CGAGTTTTTC ATTCAGCCAC AAATCTTGCG TCAGCAGGGG GCCGCGCGGG


 


1301
CCGGCGGTCA GGCTGTTTTG ATTGTCGGCA ACGGGCGCGC CGTTGTTCAT


 


1351
GGTCAGATGG GTTACGGGGC ATTTGGAGGT AGTCATCGCT CTTGTTCCTT


 


1401
TTCTCAGGTT GGTCAAATGG GGGGCAAACG GCTTACAGTA CGATTTGGCG


 


1451
GAAAGCGTAT TCGTAACCGG TTTCTTGATT GTAATAAATT TCTTGAATCG


 


1501
ACATTTTATT TTCCTTTTGC AAAAACTATG GATGCGATTA TACGCCAAGA


 


1551
TTTTCGTTAT TAA






This corresponds to the amino acid sequence <SEQ ID 1376; ORF 506.ng>:










g506.pep




1
MAVFDEVGRI AHGCGGVVKQ SLFLRVVHQV EQGARLAEVV VIVLAVVPVC


 


51
RVAVDFQRRF GEVGLLLPLA EAVGFVVRQA AVVAVGAALS VALVAVNRAT


 


101
RTIDGDLAEV HTQAVTLRVG VIEQTGLQHF IRARADTGNE VARCEGGLFH


 


151
IGEEVFGIAV QLEFAHFNQR IVFFRPNFGQ VKRMIRHFFG IGFRHDLDVH


 


201
RPFRELAALD GFVQVALMAF AVVGDDFCSF FVGQVFNPLL AAEMEFHPKT


 


251
FARFVPEAVG MRTEAVHMAV AGGNTAVAHH DGNLVQGFGQ QRPEVPVVCG


 


301
GTHIGARIAF DGFVQVGEFA RVAQEEHGRV VADHIPVAFF GIEFQRKTAD


 


351
VAFRIGCAAL ACHGGETGEH LGFFADFAEN FGAGVFGDVV CYGKRTERAR


 


401
TFGVHTAFGD DFAHEVGEFF IQPQILRQQG AARAGGQAVL IVGNGRAVVH


 


451
GQMGYGAFGG SHRSCSFSQV GQMGGKRLTV RFGGKRIRNR FLDCNKFLES


 


501
TFYFPFAKTM DAIIRQDFRY *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1377>:










m506.seq




1
ATGGCGGTAT TTGATGAAGT CGGGCGCGTC GCCCATTGCG GCGGCGGTGT


 


51
TGCCGAACAA TGCCTGTTTC TGCGCGTCGT TCATCAGGTT GAACAGGGCG


 


101
CGCGGTTGGC TGAAATAGTC GTCATCGTCT TGGCGGTAGT CCCAGTGTGC


 


151
CGCGTCGCCG TTGATTTTCA AAGGCGGTTC GGCGAAtCGg GGTTGTTGCT


 


201
GCCATTGGCC GAAGCTGTyG GGTTCGTAGT GCGGCAGGCT GCCGyAGTTG


 


251
CCGTCGGCGC GGCCTTGCCC GTyGCGsTgr TTgCTGTgAA CAsGGCAACG


 


301
CGGACGATTG ACGGGAATTT GGCGGAAGTT TACGCCCAAA CGGTAGCGTT


 


351
GTGCGTCGGC GTAATTGAAC AAACGCGCTT GCAGCATTTT ATCTsGGCTG


 


401
GCGCCGACAC CGGGAACGAG GTTGCTCGGT GCGAAGGCGG ATTGTTCCAC


 


451
ATCGGCGAAG AAGTTTTCGG GATTGCGGTT CTCAAACGGA TGATAAGGTA


 


501
CTTTTTCCGC GTCTGCTTCA GGCATGACTT GGATGTACAT CGTCCATTTC


 


551
GGAAACTCGC CGCGTTCGAT GGCTTCsTAT AAGTCGCGCT GATGGCTTTC


 


601
GCGGTCGTCG GCGATGATTT TGGCGGCTTC TTCGTTGGTC AGGTTTTTAA


 


651
TGCCTTGTTG GGTGCGGAAA TGGAATTTCA CCCAAAAACG CTCGCCTGCT


 


701
TCGTTCCAGA AGCTGTAGGT ATGCGAACCG AAGCCGTGCA TATGGCGGTA


 


751
GCCGGCGGGG ATGCCGCGGT CGCTCATCAC GATGGTAACT TGGTGCAGTG


 


801
CTTCGGGCAG CAGCGTCCAG AAGTCCCAGT TGTTTGTGGC AGAGCGCATA


 


851
TTGGTGCGCG GGTCGCGTTT GACGGCTTTG TTCAGGTCGG GGAACTTACG


 


901
CGGGTCGCGC AGGAAGAACA CGGGCGTGTT GTTGCCGACC ACATCCCAGT


 


951
TGCCTTCTTC GGTATAAAAT TTCAAGGCAA AACCGCGGAT GTCGCGTTCT


 


1001
GCATCGGCTG CGCCGCGTTC GCCTGCCACG GTGGTGAAAC GGGCGAACAT


 


1051
CTCGGTTTTT TTGCCGACTT CGCTGAAGAT TCCTTTGGCG TGCATACGGC


 


1101
GTTCGGGGAT GACTTCGCGC ACGAAGTCGG CGAGTTTTTC AGTCATCGCT


 


1151
CTTGTTCCTT TTCTCAGGTT GGTCAAATGG GGGTAAACGG CTTACAGTAC


 


1201
GATTTGGCGG AAAGCGTATT CGTAACCGGT TTCTTGATTG CAATAAATTT


 


1251
CTTGAATCGA CATTTTATTT CCCTTTTGTA AAAACTATGG ATGCGACTAT


 


1301
ACGCCAAGAT TTTCGCTATT AA






This corresponds to the amino acid sequence <SEQ ID 1378; ORF 506>:










m506.pep




1
MAVFDEVGRV AHCGGGVAEQ CLFLRVVHQV EQGARLAEIV VIVLAVVPVC


 


51
RVAVDFQRRF GESGLLLPLA EAVGFVVRQA AXVAVGAALP VAXXAVNXAT


 


101
RTIDGNLAEV YAQTVALCVG VIEQTRLQHF IXAGADTGNE VARCEGGLFH


 


151
IGEEVFGIAV QLEFAHFNQR IVFFRPNFGQ VKRMIRYFFR VCFRHDLDVH


 


201
RPFRKLAAFD GFXXVALMAF AVVGDDFGGF FVGQVFNALL GAEMEFHPKT


 


251
LACFVPEAVG MRTEAVHMAV AGGDAAVAHH DGNLVQCFGQ QRPEVPVVCG


 


301
RAHIGARVAF DGFVQVGELT RVAQEEHGRV VADHIPVAFF GIKFQGKTAD


 


351
VAFCIGCAAF ACHGGETGEH LGFFADFAED FGAGVFGDVV RYGKRTERAR


 


401
TFGVHTAFGD DFAHEVGEFF IQPQILRQQR AARTGGQAVL IVGNRRAVVH


 


451
GQMGYRAFGG SHRSCSFSQV GQMGGKRLTV RFGGKRIRNR FLDCNKFLES


 


501
TFYFPFVKTM DATIRQDFRY *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 506 shows 89.2% identity over a 520 aa overlap with a predicted ORF (ORF 506.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1379>:










a506.seq




1
ATGGCGGTAT TTGATGAAGT CGGGCGCGTC GCCCATTGCG GCGGCGGTGT


 


51
TGCCGAACAA TGCCTGTTTC TGCGCGTCGT TCATCAGGTT GAACAGGGCG


 


101
CGCGGTTGGC TGAAATAGTC GTCATCGTCT TGGCGGTAGT CCCAGTGCGC


 


151
CGCGTCGCCG TTGATTTTCA AAGGCGGTTC GGCGAAGTCG GGCTGCTGCT


 


201
GCCATTGGCC GAAGCTGTTG GGTTCGTAGT GCGGCAGGCT GCCGTAGTTG


 


251
CCGTCGGCGC GTCCTTGTCC GTCGCGCTGG TTGCTGTGAA CAGGGCAACG


 


301
CGGACGGTTG ACAGGGATTT GGCGGAAGTT CACGCCCAAG CGGTAGCGTT


 


351
GCGCGTCGGC GTAATTGAAC AAACGCGCCT GCAACATTTT ATCTGGGCTG


 


401
GCGCCGACAC CGGGAACGAG GTTGCTCGGT GCGAAGGCGG ATTGTTCCAC


 


451
ATCGGCGAAG AAGTTTTCGG GATTGCGGTT CAACTCGAAT TCGCCCACTT


 


501
CAATCAGCGG ATAGTCTTTT TTCGGCCAAA CTTTGGTCAA GTCAAACGGA


 


551
TGATACGGCA CTTTTTCCGC ATCGGCTTCA GGCATGACTT GGATGTACAT


 


601
CGTCCATTTC GGAAACTCGC CGCGCTCGAT GGCTTCGTAC AGGTCGCGCT


 


651
GATGGCTTTC ACGGTCGTCG GCGATGATTT TGGCGGCTTC TTCGTTGGTC


 


701
AGGTTTTTAA TGCCTTGTTG GGTGCGGAAA TGGAATTTCA CCCAAAAACG


 


751
CTCGCCTGCT TCGTTCCAGA AGCTGTAGGT ATGCGAACCG AAGCCGTGCA


 


801
TATGGCGGTA GCCGGCGGGG ATGCCGCGGT CGCTCATCAC GATGGTAACT


 


851
TGGTGCAGTG CTTCGGGCAG CAGCGTCCAG AAGTCCCAGT TGTTTGTGGC


 


901
AGAGCGCATA TTGGTGCGCG GGTCGCGTTT GACGGCTTTG TTCAGGTCGG


 


951
GGAACTTACG CGGGTCGCGC AGGAAGAACA CGGGCGTGTT GTTGCCGACC


 


1001
ACATCCCAGT TGCCTTCTTC GGTATAGAAC TTCAACGCAA AACCGCGGAT


 


1051
GTCGCGTTCT GCATCGGCTG CGCCGCGTTC GCCTGCCACG GTGGTGAAAC


 


1101
GGGCGAACAT CTCGGTTTTT TTGCCGACTT CGCTGAAGAT TTTGGCGCGG


 


1151
GTGTATTTGG TGATGTCGTG CGTTACGGTA AACGTACCGA ACGCGCCCGA


 


1201
ACCTTTGGCG TGCATACGGC GTTCGGGGAT GACTTCGCGC ACGAAGTCGG


 


1251
CGAGTTTTTC ATTCAGCCAC AAATCCTGCG CCAGCAGAGG GCCGCGAGGA


 


1301
CCGGCGGTCA GGCTGTTTTG ATTGTCGGCA ACAGGCGCGC CGTTGTTCAT


 


1351
GGTCAGATGG GTTACAGGGC ATTTGGAGGT ANTCATCGCT CTTGTTCCTT


 


1401
TTCTCAGGTT GGTCAAAT.G GGGGTAAACG GCTTACAGTA CGATTTGGCG


 


1451
GAAAGCGTAT TCGTAACCGG TTTCTTGATT GCAATAAATT TCTTGAATCG


 


1501
ACATTTTATT TCCCTTTTGT AAAAACTATG GATGCGACTA TACGCCAAGA


 


1551
TTTTCGCTAT TAA






This corresponds to the amino acid sequence <SEQ ID 1380; ORF 506.a>:










a506.pep




1
MAVFDEVGRV AHCGGGVAEQ CLFLRVVHQV EQGARLAEIV VIVLAVVPVR


 


51
RVAVDFQRRF GEVGLLLPLA EAVGFVVRQA AVVAVGASLS VALVAVNRAT


 


101
RTVDRDLAEV HAQAVALRVG VIEQTRLQHF IWAGADTGNE VARCEGGLFH


 


151
IGEEVFGIAV QLEFAHFNQR IVFFRPNFGQ VKRMIRHFFR IGFRHDLDVH


 


201
RPFRKLAALD GFVQVALMAF TVVGDDFGGF FVGQVFNALL GAEMEFHPKT


 


251
LACFVPEAVG MRTEAVHMAV AGGDAAVAHH DGNLVQCFGQ QRPEVPVVCG


 


301
RAHIGARVAF DGFVQVGELT RVAQEEHGRV VADHIPVAFF GIELQRKTAD


 


351
VAFCIGCAAF ACHGGETGEH LGFFADFAED FGAGVFGDVV RYGKRTERAR


 


401
TFGVHTAFGD DFAHEVGEFF IQPQILRQQR AARTGGQAVL IVGNRRAVVH


 


451
GQMGYRAFGG XHRSCSFSQV GQXGGKRLTV RFGGKRIRNR FLDCNKFLES


 


501
TFYFPFVKTM DATIRQDFRY *






m506/a506 94.8% identity in 520 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1381>:










g507.seq




1
ATGCTCTTGC CGGCTTTGCA ACAAGGCGGC GGCTTCCTGA GCGGCGGCGG


 


51
TTTCGGCCTC GTCGGGCAGG TTCAGGGCTT GGTTTTCCTG CTTCAGACGG


 


101
CCTTTGCGCT CTTCGTGCTT GGCAACGGTT TGTTCGGCAT GGGCAAGCTG


 


151
CTGCTGCTTC AACGCCAGTT CGCGGCGGAT GCGGTTTGCC TCGTCCTGCT


 


201
GGGTTTGGAA GGCAGCGTTG AGCGTGGCTT GGACTTCTTC CAATTCGGGC


 


251
AGACGCTCTT CGTGTTCGGC AACCTGCATC GCCCATTCCG CCAATTCGGT


 


301
TTGCTTTTCT TCGACCTGCA ACTCGTTTTC CTCAAGCTGC ACGCGGATTT


 


351
GCTGCTGCTC CTGCCGGATG CGTTGCAACT GCGCCTGCGC TGCCTGCTTG


 


401
TCGCGTTCGA TGCGTTGGTG CAGGTTTTGC CGGTGGCGGA TTTGTTCTTC


 


451
CAAACGGGCA ATCTGCTCGC GCAACACGCC GCGTTTGTTG CTCAATTCGT


 


501
GTACTGCCTG CTGCTGCGAC TGTTCGGCAG TCTGCAAGGC GTGTACTTCG


 


551
TTATTTAA






This corresponds to the amino acid sequence <SEQ ID 1382; ORF 507.ng>:










g507.pep




1
MLLPALQQGG GFLSGGGFGL VGQVQGLVFL LQTAFALFVL GNGLFGMGKL


 


51
LLLQRQFAAD AVCLVLLGLE GSVERGLDFF QFGQTLFVFG NLHRPFRQFG


 


101
LLFFDLQLVF LKLHADLLLL LPDALQLRLR CLLVAFDALV QVLPVADLFF


 


151
QTGNLLAQHA AFVACFVYCL LLRLFGSLQG VYFVI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1383>:










m507.seq




1
ATGCTCTTGC TGACTTTGCA ACAAGGCGGC TGCTTCCTGC GCGGCGGCGG


 


51
TTTCGGCTTC GTCGGGCAGG TTTAAGGCTT GGTTTTCCTG TTTCAGACGA


 


101
CCTTTGCGCT CTTCGTGCTT GGCAATCGTT TGTTCGGCAT GGGCAAGCTG


 


151
CTGCTGCTTC AACGCCAGTT CGCGGCGGAT GCGGTTTGCC TCGTCCTGCT


 


201
GGGTTTGGAA GGCGGCGTTG AGCGTGGCTT GGGCTTCTTC CAATTCGGGC


 


251
AGACGCTCCT CGTGTTCGGC AACCTGCATC GCCCATTCCG CCAGCTCGGT


 


301
TTGTTTTTCT TCGACCTGCA ACTCGTTTTC TTCAAGCTGC ACGCGGATTT


 


351
GCTGCTGCTC TTGATGAATG CGTTGTAACT GCGCCTGCGC TGCCTGCTTG


 


401
TCGCGTTCGA TGCGTTGGTG CAGGTTTTGC TGATGGCGGA TTTGTTCTTC


 


451
CAAACGGGCA ATCTGCTCGC GCAACACGCC GCGCTTGTTG CTCAATTCAT


 


501
GCACTGCCTG CTGCTGCGAC TGTTCGGCAG TCTGCAAGGC GTGTACTTCG


 


551
TCGTTTAA






This corresponds to the amino acid sequence <SEQ ID 1384; ORF 507>:










m507.pep




1
MLLLTLQQGG CFLRGGGFGF VGQVXGLVFL FQTTFALFVL GNRLFGMGKL


 


51
LLLQRQFAAD AVCLVLLGLE GGVERGLGFF QFGQTLLVFG NLHRPFRQLG


 


101
LFFFDLQLVF FKLHADLLLL LMNALXLRLR CLLVAFDALV QVLLMADLFF


 


151
QTGNLLAQHA ALVAQFMHCL LLRLFGSLQG VYFVV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 507 shows 87.0% identity over a 185 aa overlap with a predicted ORF (ORF 507.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1385>:










a507.seq




1
ATGCTCTTGC TGGCTTTGCA ACAAGGCGGC AGCTTCCTGC GCGGCGGCGG


 


51
TTTCGGCTTC GTCAGGCAGA TTCAGGGCTT GGTTTTCCTG TTTCAGACGA


 


101
CCTTTGCGCT CTTCGTGCTT GGCAACGGTT TGTTCGGCAT GGGCAAGCTG


 


151
CTGCTGCTTC AACGCCAGTT CGCGGCGGAT GCGGTTTGCC TCGTCCTGCT


 


201
GGGTTTGGAA GGCGGCATTG AGTGTGGCTT GGGTTTCTTC CAATTCGGGC


 


251
AGACGCTCTT CGTGTTCGGC AACCTGCATC GCCCATTCCG CCAATTCGGT


 


301
TTGCTTTTCT TCCGCCTGCA ACTCGTTTTC TTCAAGCTGC ACGCGGATTT


 


351
GCTGCTGCTC CTGATGGATG CGCTGCATCT GCGCCTGCGC CGCCTGCTTG


 


401
TCGCGTTCGA TGCGTTGGTG CAGGTTTTGC TGATGGCGGA TTTGTTCTTC


 


451
CAAACGGGCA ATCTGTTCGC GCAACACGCC GCGTTTGTTG CCCAATTCGT


 


501
GCACCGCCTG CTGCTGCGAC TGTTCGGCAG TCTGCAAGGC GTGTACTTCG


 


551
TCGTTTAA






This corresponds to the amino acid sequence <SEQ ID 1386; ORF 507.a>:










a507.pep




1
MLLLALQQGG SFLRGGGFGF VRQIQGLVFL FQTTFALFVL GNGLFGMGKL


 


51
LLLQRQFAAD AVCLVLLGLE GGIECGLGFF QFGQTLFVFG NLHRPFRQFG


 


101
LLFFRLQLVF FKLHADLLLL LMDALHLRLR RLLVAFDALV QVLLMADLFF


 


151
QTGNLFAQHA AFVAQFVHRL LLRLFGSLQG VYFVV*






m507/a507 89.7% identity in 185 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1387>:










g508.seq




1
ATGGTAGCGT TTGGCGTTGA TCAGGGCCTC CTGCTGCTGC AACAGGGCGG


 


51
TTTGGGTGGC GGCCTGAAGC TGCGGCAGCT TGGTTTGCAG GGTTTGTACG


 


101
CGGGCGTATT GCTCCCTGCC CTGTTCCTGA ATCTGCGCGA GTTTTTCCTG


 


151
CACGGCGATG TATTCTTCGT CCAGCGTGTG TACGGTTTCG GTCAACTCGT


 


201
CGAGCTTGAT GTGCTGCTCG TCGTTTTGGA ACTCGGTTTC ATAGGCGAGG


 


251
GCAAGCTCTT GCCGGCGTTC CTGCCAGTCC AGGGTTTGCT GTTCGAGCCG


 


301
GGCGATTTGC TGCCGGTAGT TTTGTTTTTG CGGGTTGAGT TTGTGGACGG


 


351
CGACTTCGGC AAGCCCGTAT TGGCGGTTGG CTTCCAACAG GGCAAGCTGC


 


401
GCCTGTTTCA GACGGCCTTG CTGCTCTTGG CGGCTGTGCG CGGTGGTTTG


 


451
CTGCTGGTGT TCGAGTTCGG CGGCGGCTTC CTGCAAAGTA GCGATGTCGT


 


501
CTGA






This corresponds to the amino acid sequence <SEQ ID 1388; ORF 508.ng>:










g508.pep




1
MVAFGVDQGL LLLQQGGLGG GLKLRQLGLQ GLYAGVLLPA LFLNLREFFL


 


51
HGDVFFVQRV YGFGQLVELD VLLVVLELGF IGEGKLLPAF LPVQGLLFEP


 


101
GDLLPVVLFL RVEFVDGDFG KPVLAVGFQQ GKLRLFQTAL LLLAAVRGGL


 


151
LLVFEFGGGF LQSSDVV






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1389>:










m508.seq




1
ATGGTAGCGT TTGGCGTTGA TCAGGGCTTC CTGCTGCTGC AACAAGGCGG


 


51
TTTGGGTGGC GGCCTGAAGC TGCGGCAGCT TGGTTTGCAG GGTTTGCACT


 


101
TTAGCGTATT GCTCCCTGCC CTGTTCCTGA ATCTGCGCGA GTTTCTCTTG


 


151
CACAACAATA TATTCTTCGT CCAAGGTCTG TACGGCTTCG CTTAATTCTT


 


201
CAAGCTTGAT GTGCTGCTCG TCGTTTTGGA ACTCGGTTTC ATAGGCGAGG


 


251
GCAAGCTCTT GCTGGCGTTC CTGCCAGTCG AGGGTTTGCT GTTCAAGCTG


 


301
GGCGATTTGC TGCCGGTAGT TTTGTTTTTG CTGGTTGAGT TTGTGGACGG


 


351
CGACTTCGGC AAGCCCGTAT TGGCGGTTGG CTTCCAACAG GGCAAGCTGC


 


401
GCCTGTTTCA GACGGCCTTG CTGCTCTTGG CGGCTGTGCG CGGTGGTTTG


 


451
CTGCTGGTGT TCGAGTTCGG CGGCGGCTTC CTGCAAGGTA ACGATGTCGT


 


501
CTGA






This corresponds to the amino acid sequence <SEQ ID 1390; ORF 508.ng>:










m508.pep




1
MVAFGVDQGF LLLQQGGLGG GLKLRQLGLQ GLHFSVLLPA LFLNLREFLL


 


51
HNNIFFVQGL YGFAXFFKLD VLLVVLELGF IGEGKLLLAF LPVEGLLFKL


 


101
GDLLPVVLFL LVEFVDGDFG KPVLAVGFQQ GKLRLFQTAL LLLAAVRGGL


 


151
LLVFEFGGGF LQGNDVV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 508 shows 86.8% identity over a 167 aa overlap with a predicted ORF (ORF 508.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1391>:










a508.seq




1
ATGGTAGCGT TTGGCGTTGA TCAGGGCTTC CTGCTGCTGC AACAGGGCGG


 


51
TTTGGGTGGC GGCCTGAAGC TGCGGCAGCT TGGTTTGCAG GGTTTGTACG


 


101
CGGGCGTATT GTTCCCTACC CTGCTCCTGA ATCTGCGCGA GTTTCTCCTG


 


151
TACGACAATA TATTCTTCGT CCAAACTCTG TACGGCTTCG CTCAACTCTT


 


201
CGAGCTTGAT GTGCTGCTCG TCGTTTTGGA ACTCGGTTTC ATAGGCGAGG


 


251
GCAAGCTCTT GCTGGCGTTC CTGCCAATCG AAGGTTTGTT GTTCAAGCTG


 


301
GGCAATTTGC TGTTGGTAGT TTTGTTTTTG CTGGTTGAGC TTGTGGACGG


 


351
CGACTTCGGC AAGCCCGTAT TGGCGGTTGG CTTCCAACAG GGCAAGCTGC


 


401
GCCTGTTTCA GACGACCTTG CTGCTCTTGG CGGCTGTGCG CGGCGGTTTG


 


451
CTGCTGGTGT TCGAGTTCGG CGGCGGCTTC CTGCAAAATG GCGATGTCGT


 


501
CTGA






This corresponds to the amino acid sequence <SEQ ID 1392; ORF 508.a>:










a508.pep




1
MVAFGVDQGF LLLQQGGLGG GLKLRQLGLQ GLYAGVLFPT LLLNLREFLL


 


51
YDNIFFVQTL YGFAQLFELD VLLVVLELGF IGEGKLLLAF LPIEGLLFKL


 


101
GNLLLVVLFL LVELVDGDFG KPVLAVGFQQ GKLRLFQTTL LLLAAVRGGL


 


151
LLVFEFGGGF LQNGDVV*






m508/a508 88.6% identity in 167 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1393>:










g509.seq




1
atggtcgctg tatgtgatga acgggctgta cagcggacgt tggtggccca


 


51
attcgcgcaa caaggcggct tgtttttgct cttcgttcag gctgttgtag


 


101
tcttccaagc ctgcgtgttg gaaaagctcg gcaaccacat cggcgtgttt


 


151
gcctgcgtgt tggcgcaggt cgagcggcat catgtggaag ccgaacacgg


 


201
acacggaacg gatgaggtct gccaaacggc cttcggcaag caggcggctg


 


251
ccgttgtcga taagggaacg ttgcaatttt ttcaaatcat cgagaaattt


 


301
ttgggccgaa gcataaggct cgagaaagcc gaatttgcag cccatgccca


 


351
aaccgagcga gcgcgctttg cccatagcgc gcgccataat gtaggcaatg


 


401
gcgcggcggt aaggttcttc ggtgcgggcg atttcttcgt caggcgagag


 


451
ggctgccagt gccattacgt cgtcgttgac tttgacgcgg cggatggaaa


 


501
gcggcagttc gcggtaaagt ttgtcgagtt cgctgcggta aaaacggaac


 


551
acggcatcgg cgtggcggcg gaaggcaaag cgcagggttt cgccagaaac


 


601
aaacggattg ccgtcgcggt cgccgccgat ccagccgccg attttaagga


 


651
tattcggaac gcggacatcg ggataggccg tctgaaagtc gtgttccatc


 


701
ttgcggtaga gtttgggcag ggcttcaaaa aagctcatcg ggaagatgga


 


751
cacgccgttg ttgatttcgt cgttgacgct gagtttgtgg cggcgcgttt


 


801
cgctggtctg ccacaagccc agaagcacgg tgtcgatttc gcggcgcagc


 


851
cgtgccagcg cgtcggcatt ggtgcagcgt tcgcgttgcg gcagcagcgc


 


901
gcggatgcgg cggttgaaat tcaaaacggt ttggcgttgc acttcggtcg


 


951
ggtgcgcggt caaaacggcg gtaacggacg tattgtccaa ctgccgctgc


 


1001
accgatttgc cgtcggcttt ccccgctttg agcctgcgga cggtttccgt


 


1051
caggctgcct tctgctgcgt tgtggccggc atcttcgtgg atttggcggc


 


1101
ggcgttcgtg gtgcacgtct tcggcgatat tcagaatctg ggcgaacagc


 


1151
ccgcaggcaa gcgtcagatc gtaggtctgc cgttcgtcca attgcggcaa


 


1201
tactttttca atcaatgccg cgctgtcgtc ggaagtggac aagagtttga


 


1251
ccgtttcgac aaccaacggc gaggcttctt cgtgcaggag gttgaacagg


 


1301
gactgtttca aaaattccgc gtccgccgcc aaagccgcgt ccttcggatt


 


1351
gttcaggata tgcagttgca tgattttcct ctcattgccg taaatactgt


 


1401
aaatgtacct caaatgccgc atccgtgcca aaccgttcac actttaacca


 


1451
ctcatgtccc gaaatgccgt ctgaagttga acgccgcccg acggcggcgt


 


1501
tacaatcgcc cgcaactgtt tttttccgaa catcatcatg accgcgaccg


 


1551
aacacgacaa cgacgacgca ctcctgctgc ggtacagccg ccacatcctc


 


1601
ttggacgaaa tcggcatcga agggcagcag aagctttccg ccgcgcatat


 


1651
tttggtcgtc ggctgcggcg gattgggcgc cgccgcccct gccctatctc


 


1701
gccgcctcgg gggtcggcac gctga






This corresponds to the amino acid sequence <SEQ ID 1394; ORF 509.ng>:










g509.pep




1
MVAVCDERAV QRTLVAQFAQ QGGLFLLFVQ AVVVFQACVL EKLGNHIGVF


 


51
ACVLAQVERH HVEAEHGHGT DEVCQTAFGK QAAAVVDKGT LQFFQIIEKF


 


101
LGRSIRLEKA EFAAHAQTER ARFAHSARHN VGNGAAVRFF GAGDFFVRRE


 


151
GCQCHYVVVD FDAADGKRQF AVKFVEFAAV KTEHGIGVAA EGKAQGFARN


 


201
KRIAVAVAAD PAADFKDIRN ADIGIGRLKV VFHLAVEFGQ GFKKAHREDG


 


251
HAVVDFVVDA EFVAARFAGL PQAQKHGVDF AAQPCQRVGI GAAFALRQQR


 


301
ADAAVEIQNG LALHFGRVRG QNGGNGRIVQ LPLHRFAVGF PRFEPADGFR


 


351
QAAFCCVVAG IFVDLAAAFV VHVFGDIQNL GEQPAGKRQI VGLPFVQLRQ


 


401
YFFNQCRAVV GSGQEFDRFD NQRRGFFVQE VEQGLFQKFR VRRQSRVLRI


 


451
VQDMQLHDFP LIAVNTVNVP QMPHPCQTVH TLTTHVPKCR LKLNAARRRR


 


501
YNRPQLFFSE HHHDRDRTRQ RRRTPAAVQP PHPLGRNRHR RAAEAFRRAY


 


551
FGRRLRRIGR RRPCPISPPR GSAR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1395>:










m509.seq




1
ATGGTCGCTG TATGTGATAA ACGGGCTGTA CAGAGGACGT TGATGGCTCA


 


51
ATTCGCGCAA CAGGGCGGTT TGTTTTTGCT CTTCGTTCAG GCGGTTGTAG


 


101
TCTTCCAAGC CTGCGTGTTG GAAAAGCTCG GCAACCACAT CGGCGTGTTT


 


151
GCCTGCGTGT TGGCGCAAGT CGAGCGGCAT CATGTGAAAG CCGAACACGG


 


201
ATACGGAACG GATGAGGTCT GCCAAACGGC CTTCGGCAAG CAGACGGCTG


 


251
CCGTTGTCGA TAAGGGAACG TTGCAATTTT TTCAAATCAT CCAGAAACTC


 


301
TTGTGCCGAA GCATAAGGCT CGAGAAAGCC GAATTTGCAG CCCATACCCA


 


351
AACCGAGCGC GCGCGCTTTG CCCATAGCGC GCGCCATAAT GTAGGCGATG


 


401
GCGCGGCGGT AGGGTTCTTC GGCGCGGGCG ATTTCTTCGT CGGGCGATTT


 


451
GTCGGACAAC GCCGTTACAT CGCCGTTGAC TTTGACGCGG CGGATGGAGA


 


501
GCGGCAGTTC GCGGTAGAGT TTGTCGAGTT CGCCGCGATA GAAGCGGAAC


 


551
ACGGCATCGG CGTGGCGGCG GAAGGCAAAG CGCAGGGTTT CGGCAGAAAC


 


601
AAACGGATTG CCGTCGCGGT CGCCGCCGAT CCAGCCGCCG ATTTTGAGGA


 


651
TGTCCGGAAC GCGGACGCCG GGATAGGCCG TCTGAAAGTC GTGTTCCATC


 


701
TTGCGGTAGA GCTTGGGCAG GGCTTCGAAA AAGCTCATCG GGAAGATGGA


 


751
CACGCCGTTG TTGATTTCGT CGTTGACGCT GAGTTTGTGG CGGCGCGTTT


 


801
CGCTGGTCTG CCACAAGCCC AGCAGGATAG TGTCGATTtC GCgGCGCAGC


 


851
CGTGCCAGCG CGTCGGCATT GGTGCAGCGT TCgCGTTGCG GCAACAGTGC


 


901
GCGGATGCGG CGGTTGAAGC TTAAGACGGT TTGGCGTTGC ACTTCGGTCG


 


951
GGTGCGCGGT CAAAACGGCG GTAACGGACG TATTGTCCAA CTGCCGCTGC


 


1001
ACCGATTTGC CGTCGGCTTT CCCCGCTTTG AGCCTGCGGA CGGTTTCCGT


 


1051
CAGGCTGCCT TCCGCGCCGC CGCGTCCGGC TTCTTCGTGG ATTTGGCGGC


 


1101
GGCGTTCGTG GTGCACGTCT TCGGCGATGT TCAAAATCTG GGCGAACAGG


 


1151
CCGCAGGCCA AGGTTAAATC GTGGGTTTGT TGTTCGTCCA ATTGCGGCAA


 


1201
TACTTTTTCA ATCAATGCCG CGCTGTCGTC GGAAGTGGAC AAGAGTTTGA


 


1251
CTGTTTCGAC AACCAACGGC GAGGCTTCTT CGTGCAGGAG GTTGAACAGG


 


1301
GATTGTTTCA GAAATTCCGC GTCCGCCGCC AAAGCCGCGT CCTTTGGATT


 


1351
GTTCAGAATA TGCAGTTGCA TGATTTTTCT CTCTCGTCTG CCGTAAATAT


 


1401
TGTAAATGTA CCCCAAATGC CGCATCCGTG CCAAACCGTT CACACTTTAA


 


1451
CCGCCCGTGT CCCGAAATGC CGTCTGAAGT TGAACGCCGC CCGACGGCAG


 


1501
CGTTACAATC GCCCGCAACT GTTTTtTTCC GAACATCATC ATGACCACGA


 


1551
CCGAACACGA CAACGACGAT GCATTCCTGC TGCGGTACAG CCGCCACATC


 


1601
CTCTTGGACG AAATCGGCAT CGAAGGGCAG CAGAAACTTT CCGCCGCGCA


 


1651
TATTTTGGTC GTCGGCTGCG GCGGTTTGGG TGCCGCCGCA CT.GCCCTAC


 


1701
CTTGCCGCTT CGGGTGTCGG CACGCTGA






This corresponds to the amino acid sequence <SEQ ID 1396; ORF 509>:










m509.pep




1
MVAVCDKRAV QRTLMAQFAQ QGGLFLLFVQ AVVVFQACVL EKLGNHIGVF


 


51
ACVLAQVERH HVKAEHGYGT DEVCQTAFGK QTAAVVDKGT LQFFQIIQKL


 


101
LCRSIRLEKA EFAAHTQTER ARFAHSARHN VGDGAAVGFF GAGDFFVGRF


 


151
VGQRRYIAVD FDAADGERQF AVEFVEFAAI EAEHGIGVAA EGKAQGFGRN


 


201
KRIAVAVAAD PAADFEDVRN ADAGIGRLKV VFHLAVELGQ GFEKAHREDG


 


251
HAVVDFVVDA EFVAARFAGL PQAQQDSVDF AAQPCQRVGI GAAFALRQQC


 


301
ADAAVEAXDG LALHFGRVRG QNGGNGRIVQ LPLHRFAVGF PRFEPADGFR


 


351
QAAFRAAASG FFVDLAAAFV VHVFGDVQNL GEQAAGQGXI VGLLFVQLRQ


 


401
YFFNQCRAVV GSGQEFDCFD NQRRGFFVQE VEQGLFQKFR VRRQSRVLWI


 


451
VQNMQLHDFS LSSAVNIVNV PQMPHPCQTV HTLTARVPKC RLKLNAARRQ


 


501
RYNRPQLFFS EHHHDHDRTR QRRCIPAAVQ PPHPLGRNRH RRAAETFRRA


 


551
YFGRRLRRFG CRRTXPTLPL RVSAR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 509 shows 87.8% identity over a 575 aa overlap with a predicted ORF (ORF 509.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1397>:










a509.seq




1
ATGGTCGCTG TATGTGATGA ACGGACTGTA CAGTGGACGT TGATGGCTCA


 


51
ATTCGCGCAA CAGGGCGGCT TGTTTTTGCT CTTCGTTGAG GCTGTTGTAG


 


101
TCTTCCAAGC CTGCGTGTTG GAAAAGCTCG GCAACCACAT CGGCGTGTTT


 


151
GCCTGCGTGT TGGCGCAGGT CGAGCGGCAT CATGTGGAAG CCGAACACGG


 


201
ATACGGAACG GATGAGGTCT GCCAAACGGC CTTCGGCAAG CAGGCGGCTG


 


251
CCGTTGTCGA TAAGGGAATG TTGCAATTTT TTCAAATCAT CGAGAAATTC


 


301
TTGTGCCGAA GCATAAGGCT CGAGAAAGCC GAATTTGCAG CCCATACCCA


 


351
AACCGAGCGC GCGCGCTTTG CCCATAGCGC GCGCCATAAT GTAGGCAATG


 


401
GCGCGACGGT AGGGTTCTTC GGCGCGGGCG GTTTCTTCGT CGGGCGATTT


 


451
GTCGGACAAC GCCATCACAT CGCCGTTGAC TTTGACGCGG CGGATGGAGA


 


501
GCGGCAGTTC GCGGTAGAGT TTGTCGAGTT CGCCACGGTA AAAACGGAAC


 


551
ACGGCATCGG CGTGGCGGCG GAAGGCAAAA CGCAAGGTTT CGGCAGAAAC


 


601
GAACGGATTG CCGTCGCGGT CGCCGCCGAT CCAGCCGCCG ATTTTGAGGA


 


651
TGTCCGGAAC GCGGACATCG GGATAGGCCG TCTGAAAGTC GTGTTCCATC


 


701
TTGCGGTAGA GCTTGGGCAG GGCTTCAAAA AAGCTCATCG GAAAGATGGA


 


751
CACGCCGTTG TTGATTTCGT CGTTGACGCT GAGTTTGTGG CGGCGCGTTT


 


801
CGCTGGTCTG CCACAAGCCC AGCAGGATAG TGTCGATTTC GCGGCGCAGC


 


851
CGTGCCAGCG CGTCGGCATT GGTACAGCGT TCGCGTTGCG GCAGCAGCGC


 


901
GCGGATGCGG CGGTTGAAAT TCAAGACGGT CTGGCGTTGC ACTTCGGTCG


 


951
GGTGCGCGGT CAAAACGGCG GTAACGGACG TATTGTCCAA CTGCCGCTGC


 


1001
ACCGATTTGC CGTCGGCTTT CCCCGCTTTG AGCCTGCGGA CGGTTTCCGT


 


1051
CAGGCTGCCT TCCGCGCCGC CGCGTCCGGC TTCTTCGTGG ATTTGGCGGC


 


1101
GGCGTTCGTG GTGCACGTCT TCGGCGATGT TCAAAATCTG GGCGAACAGG


 


1151
CCGCAGGCCA AGGTTAAATC GTGGGTTTGT TGTTCGTCCA ATTGCGGCAA


 


1201
TACTTTTTCA ATCAATGCCG CGCTGTCGTC GGAAGTGGAC AAGAGTTTGA


 


1251
CCGTTTCGAC AACCAACGGC GAGGCTTCTT CGTGCAGGAG GTTGAACAGG


 


1301
GATTGTTTCA GAAATTCCGC GTCCGCCGCC AAAGCCGCGT CCTTTGGATT


 


1351
GTTCAGAATA TGCAGTTGCA TGATTTTTCT CTCATTGCCG TAAATACTGT


 


1401
AAATGTACCT CAAATGCCGC ATCCGTGCCA AACCGTTCAC ACTTTAACCG


 


1451
CCCGTGTCCC GAAATGCCGT CTGAAGTTGA ACGCCGCCCG ACGGCAGCGT


 


1501
TACAATCGCC CACAACTGTT TTT.TCCGAA CATCATCATG ACCACGACCG


 


1551
AACACGACAA CGACGATGCA TTCCTGCTGC GGTACAGCCG CCACATCCTC


 


1601
TTGGACGAAA TTGGCATCGA AGGGCAGCAG AAACTTTCCG CCGCGCATAT


 


1651
TTTGGTCGTC GGCTGCGGCG GTTTGGGTGC CGCCGCCGAT GCCCTATCTC


 


1701
GCCGCTTCCG GCATCGGCAC GCTGA






This corresponds to the amino acid sequence <SEQ ID 1398; ORF 509.a>:










a509.pep




1
MVAVCDERTV QWTLMAQFAQ QGGLFLLFVE AVVVFQACVL EKLGNHIGVF


 


51
ACVLAQVERH HVEAEHGYGT DEVCQTAFGK QAAAVVDKGM LQFFQIIEKF


 


101
LCRSIRLEKA EFAAHTQTER ARFAHSARHN VGNGATVGFF GAGGFFVGRF


 


151
VGQRHHIAVD FDAADGERQF AVEFVEFATV KTEHGIGVAA EGKTQGFGRN


 


201
ERIAVAVAAD PAADFEDVRN ADIGIGRLKV VFHLAVELGQ GFKKAHRKDG


 


251
HAVVDFVVDA EFVAARFAGL PQAQQDSVDF AAQPCQRVGI GTAFALRQQR


 


301
ADAAVEIQDG LALHFGRVRG QNGGNGRIVQ LPLHRFAVGF PRFEPADGFR


 


351
QAAFRAAASG FFVDLAAAFV VHVFGDVQNL GEQAAGQG*I VGLLFVQLRQ


 


401
YFFNQCRAVV GSGQEFDRFD NQRRGFFVQE VEQGLFQKFR VRRQSRVLWI


 


451
VQNMQLHDFS LIAVNTVNVP QMPHPCQTVH TLTARVPKCR LKLNAARRQR


 


501
YNRPQLFXSE HHHDHDRTRQ RRCIPAAVQP PHPLGRNWHR RAAETFRRAY


 


551
FGRRLRRFGC RXPCPISPLP ASAR*






m509/a509 93.0% identity in 575 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1399>:










g510.seq




1
atgccttcgc ggacaccgca gggaaaaagg ggttattcct gccccaagcg


 


51
ggatagtgcc ttttggcagg cgttgtccat atcggttatt ttacgcgcaa


 


101
aatcgccgat tgccaaatcg ccgccgttca gggaggtttt caataggtcg


 


151
tggacgacgt tgagcgcggc cataatgacg attttttcgc tgtccgcgac


 


201
gcggccgcct tcgcggatgg cttcggcttt gccgttgagc attccgactg


 


251
cctgcaacag tgtgtctttt tcttctgccg gcgtgttgac agtcagccgg


 


301
ggcgtgcatg acttcgatgt agacttgttc gatgttcatc ctttaatcct


 


351
tattgctgcg tttcctgccg ttgggggagg cgcgctgcca gtgcgctga






This corresponds to the amino acid sequence <SEQ ID 1400; ORF 510.ng>:










g510.pep




1
MPSRTPQGKR GYSCPKRDSA FWQALSISVI LRAKSPIAKS PPFREVFNRS


 


51
WTTLSAAIMT IFSLSATRPP SRMASALPLS IPTACNSVSF SSAGVLTVSR


 


101
GVHDFDVDLF DVHPLILIAA FPAVGGGALP VR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1401>:










m510.seq




1
ATGCCTTCGC GGACACCGCA GGGnAAAAGG GGTTATTCCT GCGCCAAGCG


 


51
GGATAGTGCT TTTTGGCAGG CGTTGTCCAT ATCGGCTATT TTACGCGCAA


 


101
AATCGCCGAT TGCCAAATCG CCGCCGTTCA GGGAGGTTTT CAACAGGTCG


 


151
TGGACGACGT TGAGCGCGGC CATAATGACG ATTTTTTCGC TGTCCGCGAC


 


201
GCGTCCGCCT TCGCGGATGG CTTCGGCTTT GCCGTTGAGC ATTCCGACTG


 


251
CCTGCAACAG TGTGTCTTTT TCTTCTGCCG GCGTGTTGAC GGTCAGCCGG


 


301
GGCGTGCAwG ACTTCsAtGT GGACTTGTTC GATGTTCATC CTTTAATCCT


 


351
TATTGCTGCG TTTCCTGCCA TTGGGGGAGG CGCGCTGCCA GTGCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1402; ORF 510>:










m510.pep




1
MPSRTPQGKR GYSCAKRDSA FWQALSISAI LRAKSPIAKS PPFREVFNRS


 


51
WTTLSAAIMT IFSLSATRPP SRMASALPLS IPTACNSVSF SSAGVLTVSR


 


101
GVXDFXVDLF DVHPLILIAA FPAIGGGALP VR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 510 shows 96.2% identity over a 132 aa overlap with a predicted ORF (ORF 510.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1403>:










a510.seq




1
ATGCCTTCGC GGACACCGCA GGGAAAAAGG GGTTATTCCT GCGCCAAGCG


 


51
GGATAGTGCT TTTTGGCAGG CGTTGTCCAT ATCGGCTATT TTACGCGCAA


 


101
AATCGCCGAT TGCCAAATCG CCGCCGTTCA GGGAGGTTTT CAACAGGTCG


 


151
TGGACGACGT TGAGCGCGGC CATAATGACG ATTTTTTCGC TGTCCGCGAC


 


201
GCGTCCGCCT TCGCGGATGG CTTCGGCTTT GCCGTTGAGC ATTCCGACTG


 


251
CCTGCAACAG TGTGTCTTTT TCTTCTGCCG GCGTGTTGAC GGTCAGCCGG


 


301
G.CGTGCATG ACTTCGATGT GGACTTGTTC GATGTTCATC CTTTAATCCT


 


351
TATTGCTGCG TTTCCTGCCG TTGGGGGAGG CGCGCTGCCA GTGCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1404; ORF 510.a>:










a510.pep




1
MPSRTPQGKR GYSCAKRDSA FWQALSISAI LRAKSPIAKS PPFREVFNRS


 


51
WTTLSAAIMT IFSLSATRPP SRMASALPLS IPTACNSVSF SSAGVLTVSR


 


101
XVHDFDVDLF DVHPLILIAA FPAVGGGALP VR*






m510/a510 97.0% identity in 132 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1405>:










g512.seq




1
atgaaagtgc ttgttttagg tgcgggtgtt gccggcgtat cctccgtgtg


 


51
gtatctggca gaggccggac atgaagtaac ggtcatcgac cgcaccgagg


 


101
gtgtggcgat ggaaaccagt tttgccaatg caggccagct ttcttacggc


 


151
tataccacgc cttgggctgc acccggtatt ccgaccaaag cactgaaacg


 


201
gctgtttaaa agccatccgc ctttactgtt ccgccctgac ggcggcctgt


 


251
atcaaatcga atggctgtgg cggatgctgc aaaactgcac ggcaacgcgc


 


301
tatcaaatca ataaagagcg catggtcagg atttccgaat acagccgtga


 


351
aatgttccgc cgttttgaag cgcaaaccga catgaatttt gagggacgca


 


401
aaaaagggac gttgcagatt ttccgccaaa ccgaagaagt cgaagcggca


 


451
aaacaagaca ttgccgtttt ggaacgctac ggcgtgccgt accgccgtct


 


501
gaagcccgaa gaatgcgcag aattcgagcc tgcgctggca cgcgttaccg


 


551
ccaaaattgt cggcggtctg cacctgcctg cggatgcgac cggcgactgc


 


601
cgcctcttca ccgaaaacct gtacaaattg tgtcaagaga agggggtacg


 


651
gttctacttc aaccaaacca tcagccgcat cgaccacaac gggctgcgca


 


701
tcaaagccgt tgaaacgaaa cagggcggtt tgaaacagat gccgttgtct


 


751
gcgcgctcgg ctgcttcagc aggactgtgt tggcgcagtt ggatctcaat


 


801
ctgcccattt atcccgtcaa aggctattcc ttga






This corresponds to the amino acid sequence <SEQ ID 1406; ORF 512.ng>:










g512.pep




1
MKVLVLGAGV AGVSSVWYLA EAGHEVTVID RTEGVAMETS FANAGQLSYG


 


51
YTTPWAAPGI PTKALKRLFK SHPPLLFRPD GGLYQIEWLW RMLQNCTATR


 


101
YQINKERMVR ISEYSREMFR RFEAQTDMNF EGRKKGTLQI FRQTEEVEAA


 


151
KQDIAVLERY GVPYRRLKPE ECAEFEPALA RVTAKIVGGL HLPADATGDC


 


201
RLFTENLYKL CQEKGVRFYF NQTISRIDHN GLRIKAVETK QGGLKQMPLS


 


251
ARSAASAGLC WRSWISICPF IPSKAIP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1407>:









m512.seq (partial)










1
..GTTTTGGAAC GCTACGGCGT GCCGTACCGC CGTCTGAAAC CCGAAGAATG



 


51
  TGCAGAATTT GAGCCTGCGC TGGCACGCGT TACCGCCAAA ATTGCCGGCG


 


101
  GCCTGCACCT GCCTGCAGAT GCGACCGGCG ACTggCGCCT CTTCACTGAA


 


151
  AACCTATACA AATTGTGTCA GGAAAAGGGC GTACGGTTTC ATTTCAACCA


 


201
  AAACATCAGC CGCATCGACC ACAACGGGCT GCGCATCAAA ACCGTTGAAA


 


251
  CCAAACAGGG CGGTTTGAAG CAGATGCCGT TGTCTGCGCG CTCGGTTGCT


 


301
  TCAGCAGGAC GGTTTTGGCG CAGTTGGATC TCAATCTGCC CATTTATCCC


 


351
  GTCAAAGGCT ATTCCTTGA






This corresponds to the amino acid sequence <SEQ ID 1408; ORF 512>:









m512.pep (partial)










1
..VLERYGVPYR RLKPEECAEF EPALARVTAK IAGGLHLPAD ATGDWRLFTE



 


51
  NLYKLCQEKG VRFHFNQNIS RIDHNGLRIK TVETKQGGLK QMPLSARSVA


 


101
  SAGRFWRSWI SICPFIPSKA IP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 512 shows 93.4% identity over a 122 aa overlap with a predicted ORF (ORF 512.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1409>:










a512.seq




1
ATGAAAGTGC TTGTTTTAGG TGCTGGTGTT GCCGGCGTAT CTTCCGCGTG


 


51
GTATCTGGCA GAGGCAGGAC ATGAAGTAAC GGTCATCGAC CGCGCCGAGG


 


101
GCGTGGCGAT GGAAACCAGT TTTGCCAACG CAGGCCAGCT TTCTTACGGC


 


151
TATACCACGC CTTGGGCTGC ACCCGGTATT CCGACCAAAG CACTGAAATG


 


201
GCTGTTTAAA AGCCATCCGC CTTTGCTGTT TCGCCCCGAC GGCAGCCTGT


 


251
ATCAAATCGA ATGGCTGTGG CAGATGCTGC AACACTGCAC GGCAGCGCGC


 


301
TATCAAATCA ATAAAGAGCG CATGGTCAGG ATGTCCGAAT ACAGCCGTGA


 


351
AATGTTCCGC CGTTTTGAAG CGCAAACCGG CATGAATTTT GAGGGACGCA


 


401
AAAAAGGGAC GTTGCAGATT TTCCGCCAAA CCAAAGAAGT CGAAGCGGCA


 


451
AAACAAGACA TTGCCGTTTT GGAACGCTAC GGCGTGCCGT ACCGCCGTCT


 


501
GAAGCCCGAA GAATGCGCAG AATTCGAGCC TGCGCTGGCA CGCGTTACCG


 


551
CCAAAATTGC CGGCGGCCTG CACCTGCCCG CAGACGCGAC CGGCGACTGC


 


601
CGCCTCTTCA CTGAAAACCT GTACAAATTG TGTCAGGAAA AGGGCGTACG


 


651
GTTTCATTTC AACCAAACCA TCAGCCGCAT CGACCACAAC GGGCTGCGCA


 


701
TCAAAACCGT TGAAACGAAA CAGGGCGGTT TGAAGCAGAT GCCGTTGTCT


 


751
GCGCGCTCGG CTGCTTCAGC AGGACGGTTT TGGCGCAAGT GGATCTCAAT


 


801
CTGCCGATTT ATCCCGTCAA AGGCTATTCC TTGA






This corresponds to the amino acid sequence <SEQ ID 1410; ORF 512.a>:










a512.pep




1
MKVLVLGAGV AGVSSAWYLA EAGHEVTVID RAEGVAMETS FANAGQLSYG


 


51
YTTPWAAPGI PTKALKWLFK SHPPLLFRPD GSLYQIEWLW QMLQHCTAAR


 


101
YQINKERMVR MSEYSREMFR RFEAQTGMNF EGRKKGTLQI FRQTKEVEAA


 


151
KQDIAVLERY GVPYRRLKPE ECAEFEPALA RVTAKIAGGL HLPADATGDC


 


201
RLFTENLYKL CQEKGVRFHF NQTISRIDHN GLRIKTVETK QGGLKQMPLS


 


251
ARSAASAGRF WRKWISICRF IPSKAIP*






m512/a512 95.9% identity in 122 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1411>:










g513.seq




1
ATGGGTTCCG CGCCGAACGC CGCCGCCGCC GCCGAAGTGA AACACCCTGT


 


51
TTCGCAAGGT ATGATTCAAA TGCTGGGCGT GTTTGTCGAT ACCATCATCG


 


101
TTTGTTCTTG CACCGCCTTC ATCATCTTGA TTTACCAACA GCCTTATGGC


 


151
GATTTGAGCG GTGCGGCGCT GAcgcAGGCG GCGATTGTCA GCCAAGTGGG


 


201
GCAATGGGGC GCGGGTTTCC TCGCCGTCAT CCTGTTTATG TTTGCCTTTT


 


251
CCACCGTTAT CGGCAACTAT GCCTATGCCG AGTCCAACGT CCAATTCATC


 


301
AAAAGCCATT GGCTGATTAC CGCCGTTTTC CGTATGCTGG TTTTGGCGTG


 


351
GGTCTATTTC GGCGCGGTTG CCAATGTGCC TTTGGTCTGG GATATGGCGG


 


401
ATATGGCGAT GGGCATCATG GCGTGGATCA ACCTCGTCGC CATCCTGCTG


 


451
CTCTCGCCat TGGCGTTTAT GCTGCTGCGC GATTACACCG CCAAGCTGAA


 


501
AATGGGCAAA GACCCCGAGT TCAAACTTTc cgAACATCCG GGCCTGAAAC


 


551
GCCGCATCAA ATCCGATGTT TGGTAA






This corresponds to the amino acid sequence <SEQ ID 1412; ORF 513.ng>:










g513.pep




1
MGSAPNAAAA AEVKHPVSQG MIQMLGVFVD TIIVCSCTAF IILIYQQPYG


 


51
DLSGAALTQA AIVSQVGQWG AGFLAVILFM FAFSTVIGNY AYAESNVQFI


 


101
KSHWLITAVF RMLVLAWVYF GAVANVPLVW DMADMAMGIM AWINLVAILL


 


151
LSPLAFMLLR DYTAKLKMGK DPEFKLSEHP GLKRRIKSDV W*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1413>:










m513.seq




1
ATGGGTTCCG CGCCGAACGC CGCCGCCGCC GCCGAAGTGA AACACCCTGT


 


51
TTCGCAAGGT ATGATTCAAA TGCTGGGCGT GTTTGTCGAT ACCATCATCG


 


101
TTTGTTCTTG CACCGCCTTC ATCATCTTGA TTTACCAACA GCCTTATGGC


 


151
GATTTGAGCG GTGCGGCGCT GAcgcAGGCG GCGATTGTCA GCCAAGTGGG


 


201
GCAATGGGGC GCGGGTTTCC TCGCCGTCAT CCTGTTTATG TTTGCCTTTT


 


251
CCACCGTTAT CGGCAACTAT GCCTATGCCG AGTCCAACGT CCAATTCATC


 


301
AAAAGCCATT GGCTGATTAC CGCCGTTTTC CGTATGCTGG TTTTGGCGTG


 


351
GGTCTATTTC GGCGCGGTTG CCAATGTGCC TTTGGTCTGG GATATGGCGG


 


401
ATATGGCGAT GGGCATCATG GCGTGGATCA ACCTCGTCGC CATCCTGCTG


 


451
CTCTCGCCat TGGCGTTTAT GCTGCTGCGC GATTACACCG CCAAGCTGAA


 


501
AATGGGCAAA GACCCCGAGT TCAAACTTTc cgAACATCCG GGCCTGAAAC


 


551
GCCGCATCAA ATCCGATGTT TGGTAA






This corresponds to the amino acid sequence <SEQ ID 1414; ORF 513>:










m513.pep




1
MGSAPNAAAA AEVKHPVSQG MIQMLGVFVD TIIVCSCTAF IILIYQQPYG


 


51
DLSGAALTQA AIVSQVGQWG AGFLAVILFM FAFSTVIGNY AYAESNVQFI


 


101
KSHWLITAVF RMLVLAWVYF GAVANVPLVW DMADMAMGIM AWINLVAILL


 


151
LSPLAFMLLR DYTAKLKMGK DPEFKLSEHP GLKRRIKSDV W*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 513 shows 99.5% identity over a 191 aa overlap with a predicted ORF (ORF 513.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1415>:










a513.seq




1
ATGAACGAGA ACTTTACCGA ATGGCTGCAC GGCTGGGTCG GCGCCATCAA


 


51
CGATCCGATG TGGTCATACT TGGTTTATNT GCTTTTGGGT ACGGGGCTTT


 


101
TCTTCACCGT AACCACGGGC TTTGTCCAAT TCCGCCTGTT CGGGCGCAGC


 


151
ATCAAAGAAA TGCTCGGCGG CCGCAAACAG GGGGACGACC CTCACGGCAT


 


201
CACGCCGTTT CAGGCATTTG TAACCGGCCT TGCCAGCCGC GTGGGCGTGG


 


251
GCAATATCGC GGGCGTGGCC ATCGCCATCA AAGTCGGCGG ACCGGGCGCG


 


301
GTGTTTTGGA TGTGGGTAAC CGCCTTAATC GGTATGAGTT CGGCGTTTGT


 


351
CGAATCTTCG CTGGCGCAGC TCTTTAAAGT CCGCGACTAC GACAACCACC


 


401
ATTTCCGGGG CGGCCCTGCC TACTACATCA CTCAAGGGCT GGGGCAGAAA


 


451
TGGCTGGGCG TGTTGTTCGC CCTGAGCCTG ATTTTCTGTT TCGGCTTTGT


 


501
GTTTGAAGCG GTTCAGACCA ATACCATTGC CGATACCGTC AAAGCGGCGT


 


551
GGGGTTGGGA GCCTCATTAT GTCGGCGTCG CCCTGGTGAT TTTAACCGCG


 


601
CCGATTATCT TCGGCGGCAT CAGGCGCATA TCTAAAGCGG CGGAAATCGT


 


651
CGTCCCCCTG ATGGCGGTTT TGTACCTCTT TATCGCGCTT TTCATCATTT


 


701
TGACCAATAT TCCGATGATT CCGGACGTGT TCGGTCAGAT TTTTTCGGGC


 


751
GCGTTCAAAT TCGACGCGGC AGCAGGCGGC TTACTCGGCG GTCTGATTTC


 


801
GCAAACGATG ATGATGGGCA TCAAACGCGG CCTGTATTCC AACGAGGCGG


 


851
GTATGGGTTC CGCGCCGAAC GCCGCCGCCG CCGCCGAAGT GAAACACCCT


 


901
GTTTCGCAAG GTATGATTCA AATGCTGGGC GTGTTTGTCG ATACCATCAT


 


951
CGTTTGTTCT TGCACCGCCT TCATCATCTT GATTTACCAA CAGCCTTACG


 


1001
GCGATTTGAG CGGTGCGGCG CTGACGCAGG CGGCGATTGT CAGCCAAGTG


 


1051
GGGCAATGGG GCGCGGGCTT CCTCGCCGTC ATCCTGTTTA TGTTTGCCTT


 


1101
TTCCACCGTT ATCGGCAACT ATGCCTATGC CGAGTCCAAC GTCCAATTCA


 


1151
TCAAAAGCCA TTGGCTGATT ACCGCCGTTT TCCGTATGCT GGTTTTGGCG


 


1201
TGGGTCTATT TCGGCGCGGT TGCCAATGTG CCTTTGGTCT GGGATATGGC


 


1251
GGATATGGCG ATGGGCATTA TGGCGTGGAT CAACCTTGTC GCCATCCTGC


 


1301
TGCTCTCGCC CTTGGCGTTT ATGCTGCTGC GCGATTACAC CGCCAAGCTG


 


1351
AAAATGGGCA AAGACCCCGA GTTCAAACTT TCCGAACATC CGGGCCTGAA


 


1401
ACGCCGTATC AAATCCGACG TTTGGTAA






This corresponds to the amino acid sequence <SEQ ID 1416; ORF 513.a>:










a513.pep




1
MNENFTEWLH GWVGAINDPM WSYLVYXLLG TGLFFTVTTG FVQFRLFGRS


 


51
IKEMLGGRKQ GDDPHGITPF QAFVTGLASR VGVGNIAGVA IAIKVGGPGA


 


101
VFWMWVTALI GMSSAFVESS LAQLFKVRDY DNHHFRGGPA YYITQGLGQK


 


151
WLGVLFALSL IFCFGFVFEA VQTNTIADTV KAAWGWEPHY VGVALVILTA


 


201
PIIFGGIRRI SKAAEIVVPL MAVLYLFIAL FIILTNIPMI PDVFGQIFSG


 


251
AFKFDAAAGG LLGGLISQTM MMGIKRGLYS NEAGMGSAPN AAAAAEVKHP


 


301
VSQGMIQMLG VFVDTIIVCS CTAFIILIYQ QPYGDLSGAA LTQAAIVSQV


 


351
GQWGAGFLAV ILFMFAFSTV IGNYAYAESN VQFIKSHWLI TAVFRMLVLA


 


401
WVYFGAVANV PLVWDMADMA MGIMAWINLV AILLLSPLAF MLLRDYTAKL


 


451
KMGKDPEFKL SEHPGLKRRI KSDVW*






m513/a513 100.0% identity in 191 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1417>:










g515.seq




1
atggttcaaa tacaggttgt gcgcgccgcc ggcgttgccc gtggtctgca


 


51
ttccgagttt gcgcgcgctg taactgccga ggaaatagcc ttcgacaatg


 


101
ccgttttgaa tcacgaagcg cggcgcggtg gcaacacctt ccgcatcaaa


 


151
atagctgctg cggaaagagc gggggatgtg cggttcttcg cgcaggttga


 


201
ggaaatcggg caggactttt ttgccgatgc tgtcgatcag gaaactgctt


 


251
tggcggtaga gcgcgccgcc ggagagtgtg ccgacgaggt gtccgatcag


 


301
cccgcccgaa acggtggtat cgaagaggac ggggtagctg cctgtcggga


 


351
tgctgcggct gccgagtcgg cgcaaagtgc ggcgggcggc ggtttgaccg


 


401
atggtttcgg ggctgtccat atccggatgg cggcaggcgg aatcgtacca


 


451
gtagtcgcgc tgcattccgt tttcgtcggc ggcgacgacg ctgcaggaaa


 


501
tgctgtggtg cgtgctttgc cggtgtgcgg caaaaccgtg ggtgttgccg


 


551
taaacgtatt ggtactgtcc ggtttgcacc gccgcgcctt cggagttttc


 


601
gatgcggctg tccgtgtcca acgctgcctg ttcgcattgt tttgccaagc


 


651
cgacggcggc ttccgtatcc aaatcccatt cgtggtaaag gtcggggtcg


 


701
ccgatgtgtt gcgccatcaa ctcggggtcg gcaagtccgg cgcaaccgtc


 


751
ttcggcggtg tggcgggcga tgtcggcggc ggcgcggacg gtgtcgcgca


 


801
gggcttgttc ggagaagtcg gcggtgccgg cgcggccttt gcgtttgccg


 


851
acgtaaacgg taatgtccag cgatttgtcc tgctggaact cgatttgttc


 


901
gatttcgccc aagcgcacgc tgacgctttg tccgagcgat tcgctgaagt


 


951
cggcttcggc ggcggtcgcg cccgctgctt ttgccaagtc gagcgtgcgg


 


1001
cggcagaggt cgaggagttc ggaagcggtg tggttgaaca gcataacaat


 


1051
ctttcttggt ggagcgttgt ggcattttaa






This corresponds to the amino acid sequence <SEQ ID 1418; ORF 515.ng>:










g515.pep




1
MVQIQVVRAA GVARGLHSEF ARAVTAEEIA FDNAVLNHEA RRGGNTFRIK


 


51
IAAAERAGDV RFFAQVEEIG QDFFADAVDQ ETALAVERAA GECADEVSDQ


 


101
PARNGGIEED GVAACRDAAA AESAQSAAGG GLTDGFGAVH IRMAAGGIVP


 


151
VVALHSVFVG GDDAAGNAVV RALPVCGKTV GVAVNVLVLS GLHRRAFGVF


 


201
DAAVRVQRCL FALFCQADGG FRIQIPFVVK VGVADVLRHQ LGVGKSGATV


 


251
FGGVAGDVGG GADGVAQGLF GEVGGAGAAF AFADVNGNVQ RFVLLELDLF


 


301
DFAQAHADAL SERFAEVGFG GGRARCFCQV ERAAAEVEEF GSGVVEQHNN


 


351
LSWWSVVAF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1419>:










m515.seq
(partial)



1
..GGAAAGAGCG GGGGATGTGC GTTCTTCGCG CAGGTTGAGG AAATCGGGCA


 


51
  GGACTTTTCT GCCGATGCTG TCGATCAGGA AACTGCTTTG GCGGTAGAGC


 


101
  GCGCCGCCGG AGAGTGCGCC GACGAGGTGT CCGATAAGAC CGCCCGAAAC


 


151
  GGTGGTATCG AAGAGGACGG GGTAGCTGCC TGTCGGGATG CTGCGGCTGC


 


201
  CGAGTCGGCG CAAAGTGCGG CGGGCGGCGG TTTGACCGAT GGTTTCGGGG


 


251
  CTGTCCATAT CCGGATGGCG GCAGGCGGAA TCGTACCAGT AGTCGCGCTG


 


301
  CATGCCGTTT TCGTCGGCGG CAACGACGCT GCAGGAAATG CTGTGGTGCG


 


351
  TGCCTTGCCG GTGTGCGGCA AAACCGTGGG TGTTGCCGTA AACGTATTGG


 


401
  TAATGGCCGG TTTGCACCGC CGCGCCTTCG GAGTTTTCGA TGCGCTCATC


 


451
  CTCGTTCAGG GCGGCTTGTT CGCATTGTTT TGCCAAGCCG ACGGCGGCTk


 


501
  CCGTATCCAA ATCCCATTCG TGGTAAAGGT CGGGGTCGCC GATGTGTTTT


 


551
  GCCATCAGAC AGGCATCGGC AAGTCCGGCG CAACCGTCTT CGGCGGTGTG


 


601
  GCGGGCGATG TCGATGGCGG CTTTGACGGT GTCTTGCAGG GCTTTTTCGG


 


651
  AGAAGTCGGC AGTACTGGCG CGGCCTTTGC GTTTGCCGAC GTAAACGGTA


 


701
  ATGTCCAGCG ACTTGTCCTG CTGGAACTCG ATTTGTTsGA TTTsGCCCAG


 


751
  CCGCACGCTG ACGCTTTGTC CCAATGATTC GCTGAAATCG GCTTCGGCGG


 


801
  CGGTTGCGCC CGTCGCTTTT GCCAAGTCGA GCGTGCGGCG GCAGAGGTCG


 


851
  AGGAGTTCGG AAGCGGTGTG GTTgAACAGC ATAGAAATCT TTCTTGATGA


 


901
  TGCTTTGCGG CATTTTAA






This corresponds to the amino acid sequence <SEQ ID 1420; ORF 515>:










m515.pep
 (partial)



1
..GKSGGCAFFA QVEEIGQDFS ADAVDQETAL AVERAAGECA DEVSDKTARN


 


51
  GGIEEDGVAA CRDAAAAESA QSAAGGGLTD GFGAVHIRMA AGGIVPVVAL


 


101
  HAVFVGGNDA AGNAVVRALP VCGKTVGVAV NVLVMAGLHR RAFGVFDALI


 


151
  LVQGGLFALF CQADGGXRIQ IPFVVKVGVA DVFCHQTGIG KSGATVFGGV


 


201
  AGDVDGGFDG VLQGFFGEVG STGAAFAFAD VNGNVQRLVL LELDLXDXAQ


 


251
  PHADALSQXF AEIGFGGGCA RRFCQVERAA AEVEEFGSGV VEQHRNLSXX


 


301
  CFAAF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 515 shows 85.9% identity over a 304 aa overlap with a predicted ORF (ORF 515.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1421>:










a515.seq




1
ATGGTTCAAA TAAAGGTTGT GCGCGCCGCC GGCGTTGCCC GTGGTCTGCA


 


51
TTCCGAGTTT GCGCGCGCTG TAACTGCTGA GGAAATAGCC TTCGACAATG


 


101
CCGTTTTGAA TCACGAAGCG CGGTGCGGTG GCAACGCCTT CCGCATCAAA


 


151
ATAGCTGCTG CGGAAAGAGC GGGGGATGTG CGGTTCTTCG CGCAGGTTGA


 


201
GGAAATCGGG CAGGACTTTT TTGCCGATGC TGTCGATCAG GAAACTGCTT


 


251
TGGCGGTAGA GCGCTCCGCC GGAGAGTGCG CCGACGAGGT GTCCGATAAG


 


301
ACCGCCCGAA ACGGTGGTAT CGAAGAGGAC GGGGTAGTTG CCTGTCGGGA


 


351
TGCTGCGGCT GCCGAGTCGG CGCAAAGTGC GGCGGGCGGC GGTTTGACCG


 


401
ATGGTTTCGG GGCTGTCCAT ATCCGGATGG CGGCAGGCGG AATCGTACCA


 


451
GTAGTCGCGC TGCATGCCGT TTTCGTCGGC GGCAACGACG CTGCAGGAAA


 


501
TGCTGTGGTG CGTGCTTTGC CGGTGTGCGG CAAAACCGTA GGTGTTGCCG


 


551
TAAACGTATT GGTAATGGCC GGTTTGCACC GCCGCGCCTT CGGAGTTTTC


 


601
GATGCGCTCA TCCTCGTTCA GGGCGGCTTG TTCGCATTGT TTTGCCAAGC


 


651
CGACGGCGGC TTCCGTATCC AAATCCCATT CGTGGTAAAG GTCGGGGTCG


 


701
CCGATGTGTT GCGCCATCAA CTCGGGGTCG GCAAGTCCGG CGCAACCGTC


 


751
TTCGGCGGTG TGGCGGGCGA TGTCNNNNGC GGCGCGGACG GTGTCGCGCA


 


801
GGGCTTGTTC GGAGAAATCG GCGGTGCCGG CGCGGCCTTT GCGTTTGCCG


 


851
ACGTAAACGG TAATGTCCAG CGACTTGTCC TGCTGAAACT CGATTTGTTC


 


901
GATTTCGCCC AGCCGCACGC TGACGCTTTG TCCCAATGAT TCGCTGAAAT


 


951
CGGCTTCGGC GGCGGTTGCG CCCGTCGCTT TTGCCAAGTC GAGCGTGCGG


 


1001
CGGCAGAGGT CGAGGAGTTC GGAAGCGGTG TGGTTGAACA GCATAGAAAT


 


1051
CTTTCTTGAT GATGCTTTGC GGCATTTTAA






This corresponds to the amino acid sequence <SEQ ID 1422; ORF 515.a>:










a515.pep




1
MVQIKVVRAA GVARGLHSEF ARAVTAEEIA FDNAVLNHEA RCGGNAFRIK


 


51
IAAAERAGDV RFFAQVEEIG QDFFADAVDQ ETALAVERSA GECADEVSDK


 


101
TARNGGIEED GVVACRDAAA AESAQSAAGG GLTDGFGAVH IRMAAGGIVP


 


151
VVALHAVFVG GNDAAGNAVV RALPVCGKTV GVAVNVLVMA GLHRRAFGVF


 


201
DALILVQGGL FALFCQADGG FRIQIPFVVK VGVADVLRHQ LGVGKSGATV


 


251
FGGVAGDVXX GADGVAQGLF GEIGGAGAAF AFADVNGNVQ RLVLLKLDLF


 


301
DFAQPHADAL SQ*FAEIGFG GGCARRFCQV ERAAAEVEEF GSGVVEQHRN


 


351
LS**CFAAF*






m515/a515 92.1% identity in 304 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1423>:










g515-1.seq




1
ATGGTTCAAA TACAGGTTGT GCGCGCCGCC GGCGTTGCCC GTGGTCTGCA


 


51
TTCCGAGTTT GCGCGCGCTG TAACTGCCGA GGAAATAGCC TTCGACAATG


 


101
CCGTTTTGAA TCACGAAGCG CGGCGCGGTG GCAACACCTT CCGCATCAAA


 


151
ATAGCTGCTG CGGAAAGAGC GGGGGATGTG CGGTTCTTCG CGCAGGTTGA


 


201
GGAAATCGGG CAGGACTTTT TTGCCGATGC TGTCGATCAG GAAACTGCTT


 


251
TGGCGGTAGA GCGCGCCGCC GGAGAGTGTG CCGACGAGGT GTCCGATCAG


 


301
CCCGCCCGAA ACGGTGGTAT CGAAGAGGAC GGGGTAGCTG CCTGTCGGGA


 


351
TGCTGCGGCT GCCGAGTCGG CGCAAAGTGC GGCGGGCGGC GGTTTGACCG


 


401
ATGGTTTCGG GGCTGTCCAT ATCCGGATGG CGGCAGGCGG AATCGTACCA


 


451
GTAGTCGCGC TGCATTCCGT TTTCGTCGGC GGCAACGACG CTGCAGGAAA


 


501
TGCTGTGGTG CGTGCTTTGC CGGTGTGCGG CAAAACCGTG GGTGTTGCCG


 


551
TAAACGTATT GGTAGTGTCC GGTTTGCACC GCCGCGCCTT CGGAGTTTTC


 


601
GATGCGGCTG TCCGTGTCCA ACGCTGCCTG TTCGCATTGT TTTGCCAAGC


 


651
CGACGGCGGC TTCCGTATCC AAATCCCATT CGTGGTAAAG GTCGGGGTCG


 


701
CCGATGTGTT GCGCCATCAA CTCGGGGTCG GCAAGTCCGG CGCAACCGTC


 


751
TTCGGCGGTG TGGCGGGCGA TGTCGGCGGC GGCGCGGACG GTGTCGCGCA


 


801
GGGCTTGTTC GGAGAAGTCG GCGGTGCCGG CGCGGCCTTT GCGTTTGCCG


 


851
ACGTAAACGG TAATGTCCAG CGATTTGTCC TGCTGGAACT CGATTTGTTC


 


901
GATTTCGCCC AAGCGCACGC TGACGCTTTG TCCGAGCGAT TCGCTGAAGT


 


951
CGGCTTCGGC GGCGGTCGCG CCCGCTGCTT TTGCCAAGTC GAGCGTGCGG


 


1001
CGGCAGAGGT CGAGGAGTTC GGAAGCGGTG TGGTTGAACA GCATAACAAT


 


1051
CTTTCTTGGT GGAGCGTTGT GGCATTTTAA






This corresponds to the amino acid sequence <SEQ ID 1424; ORF 515-1.ng>:










g515-1.pep




1
MVQIQVVRAA GVARGLHSEF ARAVTAEEIA FDNAVLNHEA RRGGNTFRIK


 


51
IAAAERAGDV RFFAQVEEIG QDFFADAVDQ ETALAVERAA GECADEVSDQ


 


101
PARNGGIEED GVAACRDAAA AESAQSAAGG GLTDGFGAVH IRMAAGGIVP


 


151
VVALHSVFVG GNDAAGNAVV RALPVCGKTV GVAVNVLVVS GLHRRAFGVF


 


201
DAAVRVQRCL FALFCQADGG FRIQIPFVVK VGVADVLRHQ LGVGKSGATV


 


251
FGGVAGDVGG GADGVAQGLF GEVGGAGAAF AFADVNGNVQ RFVLLELDLF


 


301
DFAQAHADAL SERFAEVGFG GGRARCFCQV ERAAAEVEEF GSGVVEQHNN


 


351
LSWWSVVAF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1425>:










m515-1.seq




1
ATGGTTCAAA TACAGGTTGT GCGCGCCGCC GGCGTTGCCC GTGGTCTGCA


 


51
TACCGAGTTT GCGCGCGCTG TAACTGCTGA GGAAATAGCC TTCGACAATG


 


101
CCGTTTTGAA TCACGAAGCG CGGTGCGGTG GCAACGCCTT CCGCATCAAA


 


151
ATAGCTGCTG CGGAAAGAGC GGGGGATGTG CGGTTCTTCG CGCAGGTTGA


 


201
GGAAATCGGG CAGGACTTTT TTGCCGATGC TGTCGATCAG GAAACTGCTT


 


251
TGGCGGTAGA GCGCGCCGCC GGAGAGTGCG CCGACGAGGT GTCCGATAAG


 


301
ACCGCCCGAA ACGGTGGTAT CGAAGAGGAC GGGGTAGCTG CCTGTCGGGA


 


351
TGCTGCGGCT GCCGAGTCGG CGCAAAGTGC GGCGGGCGGC GGTTTGACCG


 


401
ATGGTTTCGG GGCTGTCCAT ATCCGGATGG CGGCAGGCGG AATCGTACCA


 


451
GTAGTCGCGC TGCATGCCGT TTTCGTCGGC GGCAACGACG CTGCAGGAAA


 


501
TGCTGTGGTG CGTGCCTTGC CGGTGTGCGG CAAAACCGTG GGTGTTGCCG


 


551
TAAACGTATT GGTAATGGCC GGTTTGCACC GCCGCGCCTT CGGAGTTTTC


 


601
GATGCGCTCA TCCTCGTTCA GGGCGGCTTG TTCGCATTGT TTTGCCAAGC


 


651
CGACGGCGGC TTCCGTATCC AAATCCCATT CGTGGTAAAG GTCGGGGTCG


 


701
CCGATGTGTT TTGCCATCAG ACAGGCATCG GCAAGTCCGG CGCAACCGTC


 


751
TTCGGCGGTG TGGCGGGCGA TGTCGATGGC GGCTTTGACG GTGTCTTGCA


 


801
GGGCTTTTTC GGAGAAGTCG GCAGTACTGG CGCGGCCTTT GCGTTTGCCG


 


851
ACGTAAACGG TAATGTCCAG CGACTTGTCC TGCTGGAACT CGATTTGTTC


 


901
GATTTCGCCC AGCCGCACGC TGACGCTTTG TCCCAATGA






This corresponds to the amino acid sequence <SEQ ID 1426; ORF 515-1>:










m515-1.pep




1
MVQIQVVRAA GVARGLHTEF ARAVTAEEIA FDNAVLNHEA RCGGNAFRIK


 


51
IAAAERAGDV RFFAQVEEIG QDFFADAVDQ ETALAVERAA GECADEVSDK


 


101
TARNGGIEED GVAACRDAAA AESAQSAAGG GLTDGFGAVH IRMAAGGIVP


 


151
VVALHAVFVG GNDAAGNAVV RALPVCGKTV GVAVNVLVMA GLHRRAFGVF


 


201
DALILVQGGL FALFCQADGG FRIQIPFVVK VGVADVFCHQ TGIGKSGATV


 


251
FGGVAGDVDG GFDGVLQGFF GEVGSTGAAF AFADVNGNVQ RLVLLELDLF


 


301
DFAQPHADAL SQ*






m515-1/g515-1 91.7% identity in 312 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1427>:










a515-1.seq




1
ATGGTTCAAA TAAAGGTTGT GCGCGCCGCC GGCGTTGCCC GTGGTCTGCA


 


51
TTCCGAGTTT GCGCGCGCTG TAACTGCTGA GGAAATAGCC TTCGACAATG


 


101
CCGTTTTGAA TCACGAAGCG CGGTGCGGTG GCAACGCCTT CCGCATCAAA


 


151
ATAGCTGCTG CGGAAAGAGC GGGGGATGTG CGGTTCTTCG CGCAGGTTGA


 


201
GGAAATCGGG CAGGACTTTT TTGCCGATGC TGTCGATCAG GAAACTGCTT


 


251
TGGCGGTAGA GCGCTCCGCC GGAGAGTGCG CCGACGAGGT GTCCGATAAG


 


301
ACCGCCCGAA ACGGTGGTAT CGAAGAGGAC GGGGTAGTTG CCTGTCGGGA


 


351
TGCTGCGGCT GCCGAGTCGG CGCAAAGTGC GGCGGGCGGC GGTTTGACCG


 


401
ATGGTTTCGG GGCTGTCCAT ATCCGGATGG CGGCAGGCGG AATCGTACCA


 


451
GTAGTCGCGC TGCATGCCGT TTTCGTCGGC GGCAACGACG CTGCAGGAAA


 


501
TGCTGTGGTG CGTGCTTTGC CGGTGTGCGG CAAAACCGTA GGTGTTGCCG


 


551
TAAACGTATT GGTAATGGCC GGTTTGCACC GCCGCGCCTT CGGAGTTTTC


 


601
GATGCGCTCA TCCTCGTTCA GGGCGGCTTG TTCGCATTGT TTTGCCAAGC


 


651
CGACGGCGGC TTCCGTATCC AAATCCCATT CGTGGTAAAG GTCGGGGTCG


 


701
CCGATGTGTT GCGCCATCAA CTCGGGGTCG GCAAGTCCGG CGCAACCGTC


 


751
TTCGGCGGTG TGGCGGGCGA TGTCGGCGGC GGCGCGGACG GTGTCGCGCA


 


801
GGGCTTGTTC GGAGAAATCG GCGGTGCCGG CGCGGCCTTT GCGTTTGCCG


 


851
ACGTAAACGG TAATGTCCAG CGACTTGTCC TGCTGAAACT CGATTTGTTC


 


901
GATTTCGCCC AGCCGCACGC TGACGCTTTG TCCCAATGA






This corresponds to the amino acid sequence <SEQ ID 1428; ORF 515-1.a>:










a515-1.pep




1
MVQIKVVRAA GVARGLHSEF ARAVTAEEIA FDNAVLNHEA RCGGNAFRIK


 


51
IAAAERAGDV RFFAQVEEIG QDFFADAVDQ ETALAVERSA GECADEVSDK


 


101
TARNGGIEED GVVACRDAAA AESAQSAAGG GLTDGFGAVH IRMAAGGIVP


 


151
VVALHAVFVG GNDAAGNAVV RALPVCGKTV GVAVNVLVMA GLHRRAFGVF


 


201
DALILVQGGL FALFCQADGG FRIQIPFVVK VGVADVLRHQ LGVGKSGATV


 


251
FGGVAGDVGG GADGVAQGLF GEIGGAGAAF AFADVNGNVQ RLVLLKLDLF


 


301
DFAQPHADAL SQ*






m515-1/a515-1 94.9% identity in 312 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1429>:










g516.seq




1
atgttgttcc gtaaaacgac cgccgccgtt ttggcggcaa ccttgatact


 


51
gaacggctgt acgatgatgt tgcgggggat gaacaacccg gtcagccaaa


 


101
caatcacccg caaacacgtt gacaaagacc aaatccgcgc cttcggtgtg


 


151
gttgccgaag acaatgccca attggaaaag ggcagcctgg tgatgatggg


 


201
cgggaaatac tggttcgccg tcaatcccga agattcggcg aagctgacgg


 


251
gccttttgaa ggccgggttg gacaagccct tccaaatagt tgaggatacc


 


301
ccgagctatg cccgccacca agccctgccg gtcaaattcg aagcgcccgg


 


351
cagccagaat ttcagtaccg gaggtctttg cctgcgctat gataccggca


 


401
gacctgacga catcgccaag ctgaaacagc ttgagtttaa agcggtcaaa


 


451
ctcgacaatc ggaccattta cacgcgctgc gtatccgcca aaggcaaata


 


501
ctacgccacg ccgcaaaaac tgaacgccga ttatcatttt gagcaaagtg


 


551
tgcccgccga tatttattat acggttactg aaaaacatac cgacaaatcc


 


601
aagctgtttg gaaatatctt atatacgccc cccttgttga tattggatgc


 


651
ggcggccgcg gtgctggtct tgcctatggc tctgattgca gccgcgaatt


 


701
cctcagacaa atga






This corresponds to the amino acid sequence <SEQ ID 1430; ORF 516.ng>:










g516.pep




1
MLFRKTTAAV LAATLILNGC TMMLRGMNNP VSQTITRKHV DKDQIRAFGV


 


51
VAEDNAQLEK GSLVMMGGKY WFAVNPEDSA KLTGLLKAGL DKPFQIVEDT


 


101
PSYARHQALP VKFEAPGSQN FSTGGLCLRY DTGRPDDIAK LKQLEFKAVK


 


151
LDNRTIYTRC VSAKGKYYAT PQKLNADYHF EQSVPADIYY TVTEKHTDKS


 


201
KLFGNILYTP PLLILDAAAA VLVLPMALIA AANSSDK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1431>:










m516.seq




1
ATGTTGTTCC GTAAAACGAC CGCCGCCGTT TTGGCGGCAA CCTTGATGCT


 


51
GAACGGCTGT ACGTTGATGT TGTGGGGAAT GAACAACCCG GTCAGCGAAA


 


101
CAATCACCCG CAAACACGTT GACAAAGACC AAATCCGCGC CTTCGGTGTG


 


151
GTTGCCGAAG ACAATGCCCA ATTGGAAAAG GGCAGCCTGG TGATGATGGG


 


201
CGGAAAATAC TGGTTCGTCG TCAATCCCGA AGATTCGGCG AAGCTGACGG


 


251
GCATTTTGAA GGCAGGGCTG GACAAACCCT TCCAAATAGT TGAGGATACC


 


301
CCGAGCTATG CTCGCCACCA AGCCCTGCCG GTCAAACTCG AATCGCCTGG


 


351
CAGCCAGAAT TTCAGTACCG AAGGCCTTTG CCTGCGCTAC GATACCGACA


 


401
AGCCTGCCGA CATCGCCAAG CTGAAACAGC TCGGGTTTGA AGCGGTCAAA


 


451
CTCGACAATC GGACCATTTA CACGCGCTGC GTATCCGCCA AAGGCAAATA


 


501
CTACGCCACA CCGCAAAAAC TGAACGCCGA TTACCATTTT GAGCAAAGTG


 


551
TGCCTGCCGA TATTTATTAC ACGGTTACTG AAGAACATAC CGACAAATCC


 


601
AAGCTGTTTG CAAATATCTT ATATACGCCC CCCTTTTTGA TACTGGATGC


 


651
GGCGGGCGCG GTACTGGCCT TGCCTGCGGC GGCTCTGGGT GCGGTCGTGG


 


701
ATGCCGCCCG CAAATGA






This corresponds to the amino acid sequence <SEQ ID 1432; ORF 516>:










m516.pep




1
MLFRKTTAAV LAATLMLNGC TLMLWGMNNP VSETITRKHV DKDQIRAFGV


 


51
VAEDNAQLEK GSLVMMGGKY WFVVNPEDSA KLTGILKAGL DKPFQIVEDT


 


101
PSYARHQALP VKLESPGSQN FSTEGLCLRY DTDKPADIAK LKQLGFEAVK


 


151
LDNRTIYTRC VSAKGKYYAT PQKLNADYHF EQSVPADIYY TVTEEHTDKS


 


201
KLFANILYTP PFLILDAAGA VLALPAAALG AVVDAARK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 516 shows 90.0% identity over a 231 aa overlap with a predicted ORF (ORF 516.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1433>:










a516.seq




1
ATGTTGTTCC GTAAAACGAC CGCCGCCGTT TTGGCGGCAA CCTTGATGTT


 


51
GAACGGCTGT ACGGTAATGA TGTGGGGTAT GAACAGCCCG TTCAGCGAAA


 


101
CGACCGCCCG CAAACACGTT GACAAGGACC AAATCCGCGC CTTCGGTGTG


 


151
GTTGCCGAAG ACAATGCCCA ATTGGAAAAG GGCAGCCTGG TGATGATGGG


 


201
CGGGAAATAC TGGTTCGTCG TCAATCCTGA AGATTCGGCG AAGCTGACGG


 


251
GCATTTTGAA GGCCGGGTTG GACAAGCAGT TTCAAATGGT TGAGCCCAAC


 


301
CCGCGCTTTG CCTACCAAGC CCTGCCGGTC AAACTCGAAT CGCCCGCCAG


 


351
CCAGAATTTC AGTACCGAAG GCCTTTGCCT GCGCTACGAT ACCGACAGAC


 


401
CTGCCGACAT CGCCAAGCTG AAACAGCTTG AGTTTGAAGC GGTCGAACTC


 


451
GACAATCGGA CCATTTACAC GCGCTGCGTC TCCGCCAAAG GCAAATACTA


 


501
CGCCACACCG CAAAAACTGA ACGCCGATTA TCATTTTGAG CAAAGTGTGC


 


551
CTGCCGATAT TTATTACACG GTTACGAAAA AACATACCGA CAAATCCAAG


 


601
TTGTTTGAAA ATATTGCATA TACGCCCACC ACGTTGATAC TGGATGCGGT


 


651
GGGCGCGGTG CTGGCCTTGC CTGTCGCGGC GTTGATTGCA GCCACGAATT


 


701
CCTCAGACAA ATGA






This corresponds to the amino acid sequence <SEQ ID 1434; ORF 516.a>:










a516.pep




1
MLFRKTTAAV LAATLMLNGC TVMMWGMNSP FSETTARKHV DKDQIRAFGV


 


51
VAEDNAQLEK GSLVMMGGKY WFVVNPEDSA KLTGILKAGL DKQFQMVEPN


 


101
PRFAYQALPV KLESPASQNF STEGLCLRYD TDRPADIAKL KQLEFEAVEL


 


151
DNRTIYTRCV SAKGKYYATP QKLNADYHFE QSVPADIYYT VTKKHTDKSK


 


201
LFENIAYTPT TLILDAVGAV LALPVAALIA ATNSSDK*






m516/a516 86.1% identity in 238 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1435>:










g517.seq




1
atgcatcggg tttcagacgg cattggagtg tcagtcgtgt tctgccgatt


 


51
cgtaggcttc gacgattttt tgcaccagag gatgccggac aacgtcttcg


 


101
ccggtgaagg tatggaaata cagtcctgcc acgccgtgca gtttctcacg


 


151
tgcgtctttc aatcccgatt tgatgttttt gggcaggtcg atttggctgg


 


201
tgtcgccggt aatgacggct ttcgcgccga agccgatgcg ggtcaggaac


 


251
attttcattt gttcgggcgt ggtgttttgc gcttcgtcga ggatgatgta


 


301
tgcgccgttg agcgtcctgc cgcgcatata ggcgagcggg gcgatttcaa


 


351
tcaggccttt ttcaatcagc ttggttacac ggtcaaagcc catcaggtca


 


401
tagagggcat cataaagcgg acggaggtag gggtcgactt tttgggtcag


 


451
gtctccgggc aggaagccca gtttctcacc ggcttcgacg gcaggccgaa


 


501
ctaa






This corresponds to the amino acid sequence <SEQ ID 1436; ORF 517.ng>:










g517.pep




1
MHRVSDGIGV SVVFCRFVGF DDFLHQRMPD NVFAGEGMEI QSCHAVQFLT


 


51
CVFQSRFDVF GQVDLAGVAG NDGFRAEADA GQEHFHLFGR GVLRFVEDDV


 


101
CAVERPAAHI GERGDFNQAF FNQLGYTVKA HQVIEGIIKR TEVGVDFLGQ


 


151
VSGQEAQFLT GFDGRPN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1437>:










m517.seq




1
ATGCATCGGG TTTCAGACGG CATTGGAATG TCAGTCGTGT TCTGCCGATT


 


51
CGTAGGCTTC GACGATTTTT TGCACCAAAG GATGCCGGAC AACGTCTTCG


 


101
CCGGTAAAGG TGTGGAAATA CAGCCCTTCC ACGTTGTGCA GTTTCTCACG


 


151
CGCATCTTTT AATCCCGATT TGATGTTTTT GGGCAGGTCG ATTTGGCTGG


 


201
TGTCGCCGGT AATGACGGCT TTCGCGCCGA AGCCGATGCG GGTCAGGAAC


 


251
ATTTTCATTT GTTCGGGCGT GGTGTTTTGC GCTTCGTCGA GGATGATGTA


 


301
TGCGCCGTTG AGCGTCCTGC CGCGCATATA GGCGAGCGGG GCGATTTCAA


 


351
TCAGGCCTTT TTCAATCAGC TTGGTTACAC GGTCAAAGCC CATCAGGTCA


 


401
TAGAGGGCAT CATAAAGCGG ACGAAGGTAG GGATCGACTT TCTGGGTCAG


 


451
GTCTCCGGGC AGGAAGCCCA GTTTCTCGCC GGCTTCGACG GCTGgGCGCA


 


501
CTAA






This corresponds to the amino acid sequence <SEQ ID 1438; ORF 517>:










m517.pep




1
MHRVSDGIGM SVVFCRFVGF DDFLHQRMPD NVFAGKGVEI QPFHVVQFLT


 


51
RIFXSRFDVF GQVDLAGVAG NDGFRAEADA GQEHFHLFGR GVLRFVEDDV


 


101
CAVERPAAHI GERGDFNQAF FNQLGYTVKA HQVIEGIIKR TKVGIDFLGQ


 


151
VSGQEAQFLA GFDGWAH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 517 shows 92.7% identity over a 164 aa overlap with a predicted ORF (ORF 517.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1439>:










a517.seq




1
ATGCATCGGG TTTCAGACGG CATTGGAATG TCAGTCGTGT TCTGCCGATT


 


51
CGTAGGCTTC GACGATTTTT TGCACCAAAG GATGCCGGAC AACGTCTTCG


 


101
CCGGTAAAGG TGTGGAAATA CAGCCCTTCC ACGCCGTGCA GTTTCTCACG


 


151
CGCATCTTTT AATCCCGATT TGATGTTTTT GGGCAGGTCG ATTTGGCTGG


 


201
TGTCGCCGGT AATGACGGCT TTCGCGCCGA AGCCGATGCG GGTCAGGAAC


 


251
ATTTTCATTT GTTCGGGCGT GGTGTTTTGC GCTTCGTCGA GGATGATGTA


 


301
TGCGCCGTTG AGCGTCCTGC CGCGCATATA GGCGAGCGGG GCAATCTCAA


 


351
TCAGACCTTT TTCAATCAGC TTGGTGACAC GGTCGAAGCC CATCAGGTCA


 


401
TAGAGGGCAT CATAAAGCGG ACGAAGGTAG GGATCGACTT TCTGGGTCAG


 


451
GTCACCGGGC AGAAAACCCA GTTTCTCGCC GGCTTCGACG GCAGGCCGCA


 


501
CTAA






This corresponds to the amino acid sequence <SEQ ID 1440; ORF 517.a>:










a517.pep




1
MHRVSDGIGM SVVFCRFVGF DDFLHQRMPD NVFAGKGVEI QPFHAVQFLT


 


51
RIF*SRFDVF GQVDLAGVAG NDGFRAEADA GQEHFHLFGR GVLRFVEDDV


 


101
CAVERPAAHI GERGNLNQTF FNQLGDTVEA HQVIEGIIKR TKVGIDFLGQ


 


151
VTGQKTQFLA GFDGRPH*






m517/a517 93.4% identity in 167 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1441>:










g518.seq




1
atgacgtttt cggcggcaaa gctcaacatt tcggcactga tgttgtgtct


 


51
ttcggcagga atgaccgttt tactttccgc ttttttactg ctccgaccgg


 


101
aaggcagcat cttattcaac cattttttca gcataaatat tctgacccga


 


151
agagcggcat ctccacgggc aaccgtgttc agactgcatc aggcggtacg


 


201
attccacaag atgccgaaaa ccataagcaa aatgcgtaga aactacgccg


 


251
tccgaatcac gccgcctcct cgggcggcaa cgcttcatta taacagattg


 


301
ccccttaaaa aatcagaccc tgcttttgtg gcggagtctg aaatttga






This corresponds to the amino acid sequence <SEQ ID 1442; ORF 518.ng>:










g518.pep




1
MTFSAAKLNI SALMLCLSAG MTVLLSAFLL LRPEGSILFN HFFSINILTR


 


51
RAASPRATVF RLHQAVRFHK MPKTISKMRR NYAVRITPPP RAATLHYNRL


 


101
PLKKSDPAFV AESEI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1443>:










m518.seq




1
ATGACGTTTT CGGCGGCAAA GCTCAACATT TCGGCACGGA TGTTGTGTCT


 


51
TTCGGCAGGA ATGACCGTTT TACTTTCCGC TTTTTTACTG CTCCGACCGG


 


101
AAGGCAGCAT CTTATTCAAC CATTTTTTCA GCATAAATAT TCTGACCCGA


 


151
AGAGCGGCAT CTCCACAGGC AACCGTGTTC AGACGGCATC AGGCGCGGTT


 


201
TGCAAGATGC CGTACCATAA ACAAAAGGCG TAGAAACTAC GCCGTCCGAA


 


251
TCACGCCGCC CTCGCG.GCG GCAACGCGTC ATTATAACAG ATTGCCCTCC


 


301
GCGGCAGGCT TAGTGCGGCG GGAGCGCCGC CGTTGCGCAG TAATATTGTC


 


351
TAACGGGAGG AAAAAATCAG ACCCTGCTTT TGTGGCAGAG TCTGAAATTT


 


401
GA






This corresponds to the amino acid sequence <SEQ ID 1444; ORF 518>:










m518.pep




1
MTFSAAKLNI SARMLCLSAG MTVLLSAFLL LRPEGSILFN HFFSINILTR


 


51
RAASPQATVF RRHQARFARC RTINKRRRNY AVRITPPSXA ATRHYNRLPS


 


101
AAGLVRRERR RCAVILSNGR KKSDPAFVAE SEI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 518 shows 74.1% identity over a 135 aa overlap with a predicted ORF (ORF 518.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1445>:










a518.seq




1
ATGACGTTTT CGGCGGCAAA GCTCAACATT TCGGCACGGA TGTTGTGTCT


 


51
TTCGGCAGGA ATGACCGTTT TACTTTCCGC TTTTTTACTG CTCCGACCGG


 


101
AAGGCAGCAT CTTATTCAAC CATTTTTTCA GCATAAATAT TCTAACCCGA


 


151
AGAGCGGCAT CTCCACGGGC AACCGTGTTC AGACGGCATC AGGCGGTACG


 


201
ATTCCGCAAG ATGCCGACCA TAAACAAAAG GCGTAGAAAC TACGCCGTCC


 


251
GAATCACGCC GTCCTCG.CG GCGGCAACGC GTCATTATAA CAGATTGCCC


 


301
TCC....... .......... .......... .......... ..........


 


351
.......... ...AAAAAAT CAGACCCTGC TTTTGTGGCA GAGTCTGAAA


 


401
TTTGA






This corresponds to the amino acid sequence <SEQ ID 1446; ORF 518.a>:










a518.pep




1
MTFSAAKLNI SARMLCLSAG MTVLLSAFLL LRPEGSILFN HFFSINILTR


 


51
RAASPRATVF RRHQAVRFRK MPTINKRRRN YAVRITPSSX AATRHYNRLP


 


101
S......... .......... .KKSDPAFVA ESEI*






m518/a518 79.9% identity in 134 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1447>:










g519.seq




1
atggaatttt tcattatctt gttggcagcc gtcgccgttt tcggcttcaa


 


51
atcctttgtc gtcatccccc agcaggaagt ccacgttgtc gaaaggctcg


 


101
ggcgtttcca tcgcgccctg acggccggtt tgaatatttt gattcccttt


 


151
atcgaccgcg tcgcctaccg ccattcgctg aaagaaatcc ctttagacgt


 


201
acccagccag gtctgcatca cgcgcgataa tacgcaattg actgttgacg


 


251
gcatcatcta tttccaagta accgatccca aactcgcctc atacggttcg


 


301
agcaactaca ttatggcaat tacccagctt gcccaaacga cgctgcgttc


 


351
cgttatcggg cgtatggagt tggacaaaac gtttgaagaa cgcgacgaaa


 


401
tcaacagtac cgtcgtctcc gccctcgatg aagccgccgg ggcttggggt


 


451
gtgaaagtcc tccgttacga aatcaaggat ttggttccgc cgcaagaaat


 


501
ccttcgcgca atgcaggcac aaattaccgc cgaacgcgaa aaacgcgccc


 


551
gtattgccga atccgaaggc cgtaaaatcg aacaaatcaa ccttgccagt


 


601
ggtcagcgtg aagccgaaat ccaacaatcc gaaggcgagg ctcaggctgc


 


651
ggtcaatgcg tccaatgccg agaaaatcgc ccgcatcaac cgcgccaaag


 


701
gcgaagcgga atccctgcgc cttgttgccg aagccaatgc cgaagccaac


 


751
cgtcaaattg ccgccgccct tcaaacccaa agcggggcgg atgcggtcaa


 


801
tctgaagatt gcgggacaat acgttaccgc gttcaaaaat cttgccaaag


 


851
aagacaatac gcggattaag cccgccaagg ttgccgaaat cgggaaccct


 


901
aattttcggc ggcatgaaaa attttcgcca gaagcaaaaa cggccaaata


 


951
a






This corresponds to the amino acid sequence <SEQ ID 1448; ORF 519.ng>:










g519.pep




1
MEFFIILLAA VAVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRA MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAN


 


251
RQIAAALQTQ SGADAVNLKI AGQYVTAFKN LAKEDNTRIK PAKVAEIGNP


 


301
NFRRHEKFSP EAKTAK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1449>:









m519.seq (partial)










1
..TCCGTTATCG GGCGTATGGA GTTGGACAAA ACGTTTGAAG AACGCGACGA



 


51
  AATCAACAGT ACTGTTGTTG CGGCTTTGGA CGAGGCGGCC GGGgCTTgGG


 


101
  GTGTGAAGGT TTTGCGTTAT GAGATTAAAG ACTTGGTTCC GCCGCAAGAA


 


151
  ATCCTTCGCT CAATGCAGGC GCAAATTACT GCCGAACGCG AAAAACGCGC


 


201
  CCGTATCGCC GAATCCGAAG GTCGTAAAAT CGAACAAATC AACCTTGCCA


 


251
  GTGGTCAGCG CGAAGCCGAA ATCCAACAAT CCGAAGGCGA GGCTCAGGCT


 


301
  GCGGTCAATG CGTCAAATGC CGAGAAAATC GCCCGCATCA ACCGCGCCAA


 


351
  AGGTGAAGCG GAATCCTTGC GCCTTGTTGC CGAAGCCAAT GCCGAAGCCA


 


401
  TCCGTCAAAT TGCCGCCGCC CTTCAAACCC AAGGCGGTGC GGATGCGGTC


 


451
  AATCTGAAGA TTGCGGAACA ATACGTCGCT GCGTTCAACA ATCTTGCCAA


 


501
  AGAAAGCAAT ACGCTGATTA TGCCCGCCAA TGTTGCCGAC ATCGGCAGCC


 


551
  TGATTTCTGC CGGTATGAAA ATTATCGACA GCAGCAAAAC CGCCAAaTAA






This corresponds to the amino acid sequence <SEQ ID 1450; ORF 519>:









m519.pep (partial)










1
..SVIGRMELDK TFEERDEINS TVVAALDEAA GAWGVKVLRY EIKDLVPPQE



 


51
  ILRSMQAQIT AEREKRARIA ESEGRKIEQI NLASGQREAE IQQSEGEAQA


 


101
  AVNASNAEKI ARINRAKGEA ESLRLVAEAN AEAIRQIAAA LQTQGGADAV


 


151
  NLKIAEQYVA AFNNLAKESN TLIMPANVAD IGSLISAGMK IIDSSKTAK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 519 shows 87.5% identity over a 200 aa overlap with a predicted ORF (ORF 519.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1451>:










a519.seq




1
ATGGAATTTT TCATTATCTT GCTGGCAGCC GTCGTTGTTT TCGGCTTCAA


 


51
ATCCTTTGTT GTCATCCCAC AGCAGGAAGT CCACGTTGTC GAAAGGCTCG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGCCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGACAA TACGCAGCTG ACTGTTGACG


 


251
GTATCATCTA TTTCCAAGTA ACCGACCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCGAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAAT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGCAC CGTCGTCTCC GCCCTCGATG AAGCCGCCGG AGCTTGGGGT


 


451
GTGAAGGTTT TGCGTTATGA GATTAAAGAC TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCTCA ATGCAGGCGC AAATTACTGC TGAACGCGAA AAACGCGCCC


 


551
GTATCGCCGA ATCCGAAGGT CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGCG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCAAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GTGAAGCGGA ATCCTTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGTGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTCGCCGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GTATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 1452; ORF 519.a>:










a519.pep




1
MEFFIILLAA VVVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRS MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






m519/a519 99.5% identity in 199 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1453>:










g519-1.seq




1
ATGGAATTTT TCATTATCTT GTTGGCAGCC GTCGCCGTTT TCGGCTTCAA


 


51
ATCCTTTGTC GTCATCCCCC AGCAGGAAGT CCACGTTGTC GAAAGGCTCG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGCCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGATAA TACGCAATTG ACTGTTGACG


 


251
GCATCATCTA TTTCCAAGTA ACCGATCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCAAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAGT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGTAC CGTCGTCTCC GCCCTCGATG AAGCCGCCGG GGCTTGGGGT


 


451
GTGAAAGTCC TCCGTTACGA AATCAAGGAT TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCGCA ATGCAGGCAC AAATTACCGC CGAACGCGAA AAACGCGCCC


 


551
GTATTGCCGA ATCCGAAGGC CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGTG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCCAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GCGAAGCGGA ATCCCTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGGGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTAGCCGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GCATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 1454; ORF 519-1.ng>:










g519-1.pep




1
MEFFIILLAA VAVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRA MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1455>:










m519-1.seq




1
ATGGAATTTT TCATTATCTT GTTGGTAGCC GTCGCCGTTT TCGGTTTCAA


 


51
ATCCTTTGTT GTCATCCCAC AACAGGAAGT CCACGTTGTC GAAAGGCTGG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGcCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGACAA TACGCAGCTG ACTGTTGACG


 


251
GCATCATCTA TTTCCAAGTA ACCGACCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCGAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAGT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGTAC TGTTGTTGCG GCTTTGGACG AGGCGGCCGG GGCTTGGGGT


 


451
GTGAAGGTTT TGCGTTATGA GATTAAAGAC TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCTCA ATGCAGGCGC AAATTACTGC CGAACGCGAA AAACGCGCCC


 


551
GTATCGCCGA ATCCGAAGGT CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGCG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCAAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GTGAAGCGGA ATCCTTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGTGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTCGCTGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GTATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 1456; ORF 519-1>:










m519-1.




1
MEFFIILLVA VAVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVA ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRS MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






m519-1/g519-1 99.0% identity in 315 aa overlap





The following partial DNA sequence was identified in N. meningitides <SEQ ID 1457>:










a519-1.seq




1
ATGGAATTTT TCATTATCTT GCTGGCAGCC GTCGTTGTTT TCGGCTTCAA


 


51
ATCCTTTGTT GTCATCCCAC AGCAGGAAGT CCACGTTGTC GAAAGGCTCG


 


101
GGCGTTTCCA TCGCGCCCTG ACGGCCGGTT TGAATATTTT GATTCCCTTT


 


151
ATCGACCGCG TCGCCTACCG CCATTCGCTG AAAGAAATCC CTTTAGACGT


 


201
ACCCAGCCAG GTCTGCATCA CGCGCGACAA TACGCAGCTG ACTGTTGACG


 


251
GTATCATCTA TTTCCAAGTA ACCGACCCCA AACTCGCCTC ATACGGTTCG


 


301
AGCAACTACA TTATGGCGAT TACCCAGCTT GCCCAAACGA CGCTGCGTTC


 


351
CGTTATCGGG CGTATGGAAT TGGACAAAAC GTTTGAAGAA CGCGACGAAA


 


401
TCAACAGCAC CGTCGTCTCC GCCCTCGATG AAGCCGCCGG AGCTTGGGGT


 


451
GTGAAGGTTT TGCGTTATGA GATTAAAGAC TTGGTTCCGC CGCAAGAAAT


 


501
CCTTCGCTCA ATGCAGGCGC AAATTACTGC TGAACGCGAA AAACGCGCCC


 


551
GTATCGCCGA ATCCGAAGGT CGTAAAATCG AACAAATCAA CCTTGCCAGT


 


601
GGTCAGCGCG AAGCCGAAAT CCAACAATCC GAAGGCGAGG CTCAGGCTGC


 


651
GGTCAATGCG TCAAATGCCG AGAAAATCGC CCGCATCAAC CGCGCCAAAG


 


701
GTGAAGCGGA ATCCTTGCGC CTTGTTGCCG AAGCCAATGC CGAAGCCATC


 


751
CGTCAAATTG CCGCCGCCCT TCAAACCCAA GGCGGTGCGG ATGCGGTCAA


 


801
TCTGAAGATT GCGGAACAAT ACGTCGCCGC GTTCAACAAT CTTGCCAAAG


 


851
AAAGCAATAC GCTGATTATG CCCGCCAATG TTGCCGACAT CGGCAGCCTG


 


901
ATTTCTGCCG GTATGAAAAT TATCGACAGC AGCAAAACCG CCAAATAA






This corresponds to the amino acid sequence <SEQ ID 1458; ORF 519-1.a>:










a519-1.pep.




1
MEFFIILLAA VVVFGFKSFV VIPQQEVHVV ERLGRFHRAL TAGLNILIPF


 


51
IDRVAYRHSL KEIPLDVPSQ VCITRDNTQL TVDGIIYFQV TDPKLASYGS


 


101
SNYIMAITQL AQTTLRSVIG RMELDKTFEE RDEINSTVVS ALDEAAGAWG


 


151
VKVLRYEIKD LVPPQEILRS MQAQITAERE KRARIAESEG RKIEQINLAS


 


201
GQREAEIQQS EGEAQAAVNA SNAEKIARIN RAKGEAESLR LVAEANAEAI


 


251
RQIAAALQTQ GGADAVNLKI AEQYVAAFNN LAKESNTLIM PANVADIGSL


 


301
ISAGMKIIDS SKTAK*






m519-1/a519-1 99.0% identity in 315 aa overlap





Expression of ORF 519
The primer described in Table 1 for ORF 519 was used to locate and clone ORF 519. ORF 519 was cloned in pET and pGex vectors and expressed in E. coli as above described. The products of protein expression and purification were analyzed by SDS-PAGE. FIG. 4A shows the results of affinity purification, and FIG. 4B shows the expression in E. coli. Purified Nis-fusion protein was used to immunize mice whose sera were used for ELISA (positive result), FACS analysis (FIG. 4C), western blot (FIG. 1E), and a bactericidal assay (FIG. 4D). These experiments confirm that 519 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 519 are provided in FIG. 8. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 519 and the amino acid sequence encoded thereby as provided herein.
The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1459>:









g520.seq




1
atgcctgcgc ttctttcaat acgtcgggca aacgcgctgc ctttttcgcg


 


51
catttcggaa aggatgaagt tgctggtgcc gttaataatg ccggcgatgg


 


101
atttaatcct gtttgccgcc aaaccttcgc gcacggcttt gatgattggg


 


151
ataccgcccg ctactgccgc ttcaaattgg acgatgacgt tttgtttttc


 


201
cgccagcggg aagatttcgt tgccgtattc ggcgagcagt tttttgttgg


 


251
cggtaacgat gtgtttgccg ttttcaatgg ctttcaacac cgcttctttg


 


301
gcaatgcccg tgccgccgaa caattcgacc aagacatcga cgtctttacg


 


351
cgcgaacagt tcgaacggat cttttgacaa gggcgggcga cgggccgatt


 


401
ttggcgggct ttttcttcgc ttaagtcgca catggcagaa atacggattt


 


451
cgcgccccaa gcggcgggaa atttcctctg cgttgtcccg caacacggca


 


501
gccgcaccgc cgccgaccgt acctaagcct aaaagaccga tgtttactgg


 


551
cttcattgtg tctccttgta agccgactga aatgtaaata ttga






This corresponds to the amino acid sequence <SEQ ID 1460; ORF 520.ng>:










g520.pep




1
MPALLSIRRA NALPFSRISE RMKLLVPLIM PAMDLILFAA KPSRTALMIG


 


51
IPPATAASNW TMTFCFSASG KISLPYSASS FLLAVTMCLP FSMAFNTASL


 


101
AMPVPPNNST KTSTSLRANS SNGSFDKGGR RADFGGLFLR LSRTWQKYGF


 


151
RAPSGGKFPL RCPATRQPHR RRPYLSLKDR CLLASLCLLV SRLKCKY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1461>:










m520.seq




1
ATGCCTGCGC TTCTTTCAGT ACATCG.GCA AACGCGCTGC CTTTTTCGCG


 


51
CATTTCGGrk AGGATGAAGT TGCTGGTGCC GTTAATAATG CCGGCGATGG


 


101
ATTTAATCCT GTTTGCCGCC AAACCTTCGC GCAGGGCTTT GATGATTGGG


 


151
ATACCGCCCG CTACTGCCGC TTCAAATTGG ACGATGACGT TTTGTTTTTC


 


201
CGCCAGCGGG AAGATTTCGT TGCCGTATTC GGCGAGCAGT TTTTTGTTGG


 


251
CGGTAACGAT GTGTTTGCCG TTTTCAATGG CTTTCAACAC CGCATCTTTG


 


301
GCAATGCCGG TACCGCCGaA CAATTCGACG ACGACATCGA CGTCTTCACG


 


351
TGCGACCAGT TCGAACGGAT CTTTGACAAA GGCTGc.CGG ACGGGCAGGT


 


401
TTGTCGGGCT TTTTCTTCAC TCAAATCGCA CACGGCAGAA ATACGGATTT


 


451
CGCGCCCCAA GCGACGGGAA ATTTCCTCCG CGTTGTCsCG CAACACGGCA


 


501
GCCGTACCGC CGCCGACCGT ACCCAAACCT AAAAGACCGA TGTTTACTGG


 


551
CTTCATTGTG TCTCCTTGTA AGCCGACTGA AATGTAAATA TTGA






This corresponds to the amino acid sequence <SEQ ID 1462; ORF 520>:










m520.pep




1
MPALLSVHXA NALPFSRISX RMKLLVPLIM PAMDLILFAA KPSRRALMIG


 


51
IPPATAASNW TMTFCFSASG KISLPYSASS FLLAVTMCLP FSMAFNTASL


 


101
AMPVPPNNST TTSTSSRATS SNGSLTKAXR TGRFVGLFLH SNRTRQKYGF


 


151
RAPSDGKFPP RCXATRQPYR RRPYPNLKDR CLLASLCLLV SRLKCKY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 520 shows 87.3% identity over a 197 aa overlap with a predicted ORF (ORF 520.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1463>:










a520.seq




1
ATGCCTGCGC TTCTTTCAGT ACATCGG.CA AACGCGCTGC CTTTTTCGCG


 


51
CATTTCGGAG AGGATGAAGT TGCTGGTGCC GTTAATAATG CCGGCGATGG


 


101
ATTTAATCCT GTTTGCCGCC AAACCTTCGC GCAGGGCTTT GATGATTGGG


 


151
ATACCGCCCG CTACTGCCGC TTCAAATTGG ACGATGACGT TTTGTTTTTC


 


201
CGCCAGCGGG AAGATTTCGT TGCCGTATTC GGCGAGCAGT TTTTTGTTGG


 


251
CGGTAACGAT GTGTTTGCCG TTTTCAATGG CTTTCAACAC CGCATCTTTG


 


301
GCAATGCCGG TACCGCCGAA CAATTCGACG ACGACATCGA CGTCTTCACG


 


351
TGCGACCAGT TCGAACGGAT CTTTGACAAA GGCTG..CGG ACGGGCAGGT


 


401
TTGTCGGGCT TTTTCTTCAC TCAAATCGCA CACGGCAGAA ATACGGATTT


 


451
CGCGCCCCAA GCGACGGGAA ATTTCCTCCG CGTTGTCCCG CAACACGGCA


 


501
GCCGTACCGC CGCCGACCGT ACCCAAACCT AAAAGACCGA TGTTTACTGG


 


551
CTTCATTGTG TCTCCTTGTA AGCCGACTGA AATGTAAATA TTGA






This corresponds to the amino acid sequence <SEQ ID 1464; ORF 520.a>:










a520.pep




1
MPALLSVHRX NALPFSRISE RMKLLVPLIM PAMDLILFAA KPSRRALMIG


 


51
IPPATAASNW TMTFCFSASG KISLPYSASS FLLAVTMCLP FSMAFNTASL


 


101
AMPVPPNNST TTSTSSRATS SNGSLTKAXR TGRFVGLFLH SNRTRQKYGF


 


151
RAPSDGKFPP RCPATRQPYR RRPYPNLKDR CLLASLCLLV SRLKCKY*






m520/a520 98.0% identity in 197 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1465>:










g520-1.seq




1
ATGAAGTTGC TGGTGCCGTT AATAATGCCG GCGATGGATT TAATCCTGTT


 


51
TGCCGCCAAA CCTTCGCGCA GGGCTTTGAT GATTGGGATA CCGCCCGCTA


 


101
CTGCCGCTTC AAATTGGACG ATGACGTTTT GTTTTTCCGC CAGCGGGAAG


 


151
ATTTCGTTGC CGTATTCGGC GAGCAGTTTT TTGTTGGCGG TAACGATGTG


 


201
TTTGCCGTTT TCAATGGCTT TCAACACCGC TTCTTTGGCA ATGCCCGTGC


 


251
CGccgAACAA TTCGACGACG ACATCGACGT CTTTACGCGC GACCAGTtCG


 


301
AACGGATCTT TGACAAAGGC GGCGGACGGG CAGATTTGGC GGGCTTTTTC


 


351
TTCGCTTAAG TCGCACATGG CAGAAATACG GATTTCGCGC CCCAAGCGGC


 


401
GGGAAATTTC CTCTGCGTTG TCCCGCAACA CGGCAGCCGC ACCGCCGCCG


 


451
ACCgTACCTA AGCCTAAAAG ACCGATGTTT ACTGGCTTCA TTGTGTCTCC


 


501
TTGTAAGCCG ACTGAAATGT AA






This corresponds to the amino acid sequence <SEQ ID 1466; ORF 520-1.ng>:










g520-1.pep




1
MKLLVPLIMP AMDLILFAAK PSRRALMIGI PPATAASNWT MTFCFSASGK


 


51
ISLPYSASSF LLAVTMCLPF SMAFNTASLA MPVPPNNSTT TSTSLRATSS


 


101
NGSLTKAADG QIWRAFSSLK SHMAEIRISR PKRREISSAL SRNTAAAPPP


 


151
TVPKPKRPMF TGFIVSPCKP TEM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1467>:










m520-1.seq




1
ATGAAGTTGC TGGTGCCGTT AATAATGCCG GCGATGGATT TAATCCTGTT


 


51
TGCCGCCAAA CCTTCGCGCA GGGCTTTGAT GATTGGGATA CCGCCCGCTA


 


101
CTGCCGCTTC AAATTGGACG ATGACGTTTT GTTTTTCCGC CAGCGGGAAG


 


151
ATTTCGTTGC CGTATTCGGC GAGCAGTTTT TTGTTGGCGG TAACGATGTG


 


201
TTTGCCGTTT TCAATGGCTT TCAACACCGC ATCTTTGGCA ATGCCGGTAC


 


251
CGCCGAACAA TTCGACGACG ACATCGACGT CTTCACGTGC GACCAGTTCG


 


301
AACGGATCTT TGACAAAGGC TGCGGACGGG CAGGTTTGTC GGGCTTTTTC


 


351
TTCACTCAAA TCGCACACGG CAGAAATACG GATTTCGCGC CCCAAGCGAC


 


401
GGGAAATTTC CTCCGCGTTG TCCCGCAACA CGGCAGCCGT ACCGCCGCCG


 


451
ACCGTACCCA AACCTAAAAG ACCGATGTTT ACTGGCTTCA TTGTGTCTCC


 


501
TTGTAAGCCG ACTGAAATGT AA






This corresponds to the amino acid sequence <SEQ ID 1468; ORF 520-1>:










m520-1.pep




1
MKLLVPLIMP AMDLILFAAK PSRRALMIGI PPATAASNWT MTFCFSASGK


 


51
ISLPYSASSF LLAVTMCLPF SMAFNTASLA MPVPPNNSTT TSTSSRATSS


 


101
NGSLTKAADG QVCRAFSSLK SHTAEIRISR PKRREISSAL SRNTAAVPPP


 


151
TVPKPKRPMF TGFIVSPCKP TEM*






g520-1/m520-1 97.1% identity in 173 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1469>:










a520-1.seq




1
ATGAAGTTGC TGGTGCCGTT AATAATGCCG GCGATGGATT TAATCCTGTT


 


51
TGCCGCCAAA CCTTCGCGCA GGGCTTTGAT GATTGGGATA CCGCCCGCTA


 


101
CTGCCGCTTC AAATTGGACG ATGACGTTTT GTTTTTCCGC CAGCGGGAAG


 


151
ATTTCGTTGC CGTATTCGGC GAGCAGTTTT TTGTTGGCGG TAACGATGTG


 


201
TTTGCCGTTT TCAATGGCTT TCAACACCGC ATCTTTGGCA ATGCCGGTAC


 


251
CGCCGAACAA TTCGACGACG ACATCGACGT CTTCACGTGC GACCAGTTCG


 


301
AACGGATCTT TGACAAAGGC TGCGGACGGG CAGGTTTGTC GGGCTTTTTC


 


351
TTCACTCAAA TCGCACACGG CAGAAATACG GATTTCGCGC CCCAAGCGAC


 


401
GGGAAATTTC CTCCGCGTTG TCCCGCAACA CGGCAGCCGT ACCGCCGCCG


 


451
ACCGTACCCA AACCTAAAAG ACCGATGTTT ACTGGCTTCA TTGTGTCTCC


 


501
TTGTAAGCCG ACTGAAATGT AA






This corresponds to the amino acid sequence <SEQ ID 1470; ORF 520-1.a>:










a520-1.pep




1
MKLLVPLIMP AMDLILFAAK PSRRALMIGI PPATAASNWT MTFCFSASGK


 


51
ISLPYSASSF LLAVTMCLPF SMAFNTASLA MPVPPNNSTT TSTSSRATSS


 


101
NGSLTKAADG QVCRAFSSLK SHTAEIRISR PKRREISSAL SRNTAAVPPP


 


151
TVPKPKRPMF TGFIVSPCKP TEM*






m520-1/a520-1 100.0% identity in 173 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1471>:










g521.seq




1
ATGAAATCAA AACTCCCCTT AATCCTAATC AACCTTTCCC TGATTTCAAG


 


51
CCCATTGGGT GCGAATGCGG CCAAAATCTA TACCTGCACA ATCAACGGAG


 


101
AAACCGTTTA CACCACCAAG CCGTCTAAAA GCTGCCACTC AACCGATTTG


 


151
CCCCCAATCG GCAACTACAG CAGCGAACGC TATATCCTGC CCCAAACTCC


 


201
CGAACCGGCA CCATCACCGT CAAACGGCGG ACAGGCTGTC AAATATAAAG


 


251
CCCCGGTCAA AACAGTATCC AAGCCGGCAA AATCCAATAC GCCGCCTCAA


 


301
CAAGCACCTG TAAATAACAG CAGACGCTCC ATTCTcgaag caGaattaag


 


351
cAatgaacgc aaagccctGa ctGaAGCCCA AAAAATGTTA TCACAagcac


 


401
gtCtGGCAAA AGGCGgcaAC AtcaaCCatc aaaAaatcaa cgcattgtaa


 


451
AGCAATGTTt tggacAGACA GCAAAATaTC Caagcactgc aaaGAgAATt


 


501
GGGACGTATG TAA






This corresponds to the amino acid sequence <SEQ ID 1472; ORF 521.ng>:










g521n.pep




1
MKSKLPLILI NLSLISSPLG ANAAKIYTCT INGETVYTTK PSKSCHSTDL


 


51
PPIGNYSSER YILPQTPEPA PSPSNGGQAV KYKAPVKTVS KPAKSNTPPQ


 


101
QAPVNNSRRS ILEAELSNER KALTEAQKML SQARLAKGGN INHQKINAL*


 


151
SNVLDRQQNI QALQRELGRM *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1473>:










m521.seq




1
ATGAAATCAA AACTCCTCTT AATCCTAATC AACTTTTCCC TGATTTCAAG


 


51
CCCATTGGGT GCGAATGCGG CCAAAATCTA sACCTGCACA ATCAACGGAG


 


101
AAACCGTTTA CACCAsCAAG CCGTCCAAAA GCTGCCACTC AACCGATTTG


 


151
CCCCCAATCG GCAACTACAG CAGCGAACGC TATATCCCGC CCCAAACGCC


 


201
CGAACCGGTA TCATCACCGT CAAACGGCGG ACwGGTTGTC AAATATAAAG


 


251
CCCCGGTCAA AACAGTATCC AAGCCGGCAA AATCCArTAC GCCGCCGCCG


 


301
CAACAAGCAC CCTCAAACAA CAGCAGACGC TCCATTCTCG AAACAGAATT


 


351
GAGCAACGAA CGCAAAGCAT TGGTTGAAGC CCAAAAAATG TTATCACAAG


 


401
CACGTCTGGC AAAGGGCGGC AACATCAACC ATCAAGAAAT AAATGCATTA


 


451
CAAAGCAATG TATTGGACAG GCAGCAAAAT ATTCAAGCCC TGCAAAGGGA


 


501
ACTGGGGCGT ATGTAA






This corresponds to the amino acid sequence <SEQ ID 1474; ORF 521>:










m521.pep




1
MKSKLLLILI NFSLISSPLG ANAAKIXTCT INGETVYTXK PSKSCHSTDL


 


51
PPIGNYSSER YIPPQTPEPV SSPSNGGXVV KYKAPVKTVS KPAKSXTPPP


 


101
QQAPSNNSRR SILETELSNE RKALVEAQKM LSQARLAKGG NINHQEINAL


 


151
QSNVLDRQQN IQALQRELGR M*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 521 shows 90.6% identity over a 171 aa overlap with a predicted ORF (ORF 521.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1475>:










a521.seq




1
ATGAAATCAA AACTCCCCTT AATCCTAATC AACTTTTCCC TGATTTCAAG


 


51
CCCATTGGGT GCGAATGCGG CCAAAATCTA CACCTGCACA ATCAACGGAG


 


101
AAACCGTTTA CACCACCAAG CCGTCCAAAA GCTGCCTCTC AACCGATTTG


 


151
CCCCCAATCG GCAACTACAG CAGCGAACGC TATATCCCGC CCCAAACATC


 


201
CGAACCGACA CCATCACCGT CAAACGGCGG ACAGGCTGTC AAATATAAAG


 


251
CCCCGGTCAA AACAGTATCC AAGCCGGCAA AATCCAATAC GCCGCCGCCG


 


301
CAACAAGCAC CCTCAAACAA CAGCAGACGC TCCATTCTCG AAACAGAATT


 


351
GAGCAACGAA CGCAAAGCAT TGGTTGAAGC CCAAAAAATG TTATCACAAG


 


401
CACGTCTGGC AAAAGGCGGC AACATCAACC ATCAAGAAAT CAACGCATTG


 


451
CAAAGCAATG TATTGGACAG GCAGCAAAAT ATCCAAGCAC TGCAAAGAGA


 


501
ATTGGGACGT ATGTAA






This corresponds to the amino acid sequence <SEQ ID 1476; ORF 521.a>:










a521.pep




1
MKSKLPLILI NFSLISSPLG ANAAKIYTCT INGETVYTTK PSKSCLSTDL


 


51
PPIGNYSSER YIPPQTSEPT PSPSNGGQAV KYKAPVKTVS KPAKSNTPPP


 


101
QQAPSNNSRR SILETELSNE RKALVEAQKM LSQARLAKGG NINHQEINAL


 


151
QSVLDRQQN IQALQRELGR M*






m521/a521 94.2% identity in 171 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1477>:










g522.seq




1
atgactgagc cgaaacacga aacgccgacg gaagagcagg ttgccgcgcg


 


51
caaaaaagca aaagccaaaa tccgcaccat ccgcatttgg gcgtgggtca


 


101
ttttggcgtt gctcgcttca accgccctgc tctcccaatg cgcgatgtcc


 


151
aaaccgcagg caaaacagaa aattgtcgag tcttgcatga aaaatattcc


 


201
gtttgctgaa aaatggcaga acgatttgaa agcgcgcggc ttggatgcgg


 


251
acaatacccg tctcgccgtc gactactgca aatgtatgtg ggagcagcct


 


301
ttggacggat tgagcgagaa acagatcagc tccttcggca aactcggtgc


 


351
acaagaacag cttgacctgc tcggcggcgc aaacgcgttt gaaactcgag


 


401
acaaacaatg tgtcgcggat ttgaaagccg attga






This corresponds to the amino acid sequence <SEQ ID 1478; ORF 522.ng>:










g522.pep




1
MTEPKHETPT EEQVAARKKA KAKIRTIRIW AWVILALLAS TALLSQCAMS


 


51
KPQAKQKIVE SCMKNIPFAE KWQNDLKARG LDADNTRLAV DYCKCMWEQP


 


101
LDGLSEKQIS SFGKLGAQEQ LDLLGGANAF ETRDKQCVAD LKAD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1479>:










m522.seq




1
ATGACTGAGC CGAAACACGA AATGCTGACG AAAGAGCAGG TTGCCGCGCG


 


51
CAAAAAAGCA AAAGCCAAAA TCCGCACCAT CCGCATTTGG GCGTGGGTCA


 


101
TTTTGGCGTT GCTCGCTTTA ACCGCCCTGC TCTCCCAATG CGCGATGTCC


 


151
AAACCGCAGG CAAAACAGAA AATTGTCGAG TCTTGCGTGA AGAATATTCC


 


201
GTTTGCCGAA AAATGGCAAA ACGATTTGCG GGCCCGCGGT TTAGATTCAA


 


251
ACAATACCCG CCTCGCCGTC GACTACTGCA AATGTATGTG GGAGCAGCCT


 


301
TTGGACAGAT TGAGCGAGAA ACAGATTAGA TCCTTCGGCA AACTCGGCGC


 


351
ACAAGAACAG CTTGACCTGC TCGGCGGCGC AAATGCCTTT GAAGCACGTG


 


401
ACAAGCAGTG TGTTGCCGAT TTGAAATCAG AATAA






This corresponds to the amino acid sequence <SEQ ID 1480; ORF 522>:










m522.pep




1
MTEPKHEMLT KEQVAARKKA KAKIRTIRIW AWVILALLAL TALLSQCAMS


 


51
KPQAKQKIVE SCVKNIPFAE KWQNDLRARG LDSNNTRLAV DYCKCMWEQP


 


101
LDRLSEKQIR SFGKLGAQEQ LDLLGGANAF EARDKQCVAD LKSE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 522 shows 91.0% identity over a 144 aa overlap with a predicted ORF (ORF 522.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1481>:










a522.seq




1
ATGACTGAGC CGAAACACGA AATGCCGACG GAAGAGCAGG TTGCCGCGCG


 


51
CAAAAAAGCA AAAGCCAAAA TCCGCACCAT CCGCATTTGG GCATGGGTCA


 


101
TTTTGGCGTT GCTCGCTTCA ACCGCCCTGC TCTCCCAATG CGCGATGTCC


 


151
AAACCGCAGG CAAAACAGAA AATTGTCGAG TCTTGCGTGA AGAATATTCC


 


201
GTTTGCCGAA AAATGGCAAA ACGATTTGCG GGCCCGCGGT TTAGATTCAA


 


251
ACAATACCCG CCTTACCGTC GACTACTGCA AATGTATGTG GGAGCAGCCT


 


301
TTGGACAGAT TGAGCGAGAA ACAGATTAGT TCCTTCGGCA AACTCGGCGC


 


351
ACAAGAACAG CTTGACCTGC TCGGCGGCGC AAATGCCTTT GAAACGCGAG


 


401
ACAAGCAGTG TGTTGCCGAT TTGAAATCAG AATAA






This corresponds to the amino acid sequence <SEQ ID 1482; ORF 522.a>:










a522.pep




1
MTEPKHEMPT EEQVAARKKA KAKIRTIRIW AWVILALLAS TALLSQCAMS


 


51
KPQAKQKIVE SCVKNIPFAE KWQNDLRARG LDSNNTRLTV DYCKCMWEQP


 


101
LDRLSEKQIS SFGKLGAQEQ LDLLGGANAF ETRDKQCVAD LKSE*






m522/a522 95.8% identity in 144 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1483>:










g523.seq




1
atgactgtat ggtttgttgc cgctgttgcc gtcttaatca tcgaattatt


 


51
gacgggaacg gtttatcttt tggttgtcag cgcggctttg gcgggttcgg


 


101
gcattgccta cgggctgact ggcagcacgc ctgccgccgt cttgaccgcc


 


151
gcactgcttt ccgcgctggg catttggttc gtacatgcca aaaccgccgt


 


201
gggaaaagtt gaaacggatt catatcagga tttggatacc ggaaaatatg


 


251
ccgaaatcct ccgatacaca ggcggcaacc gttacgaagt tttttatcgc


 


301
ggtacgcact ggcaggcgca aaatacgggg caggaagtgt ttgaaccggg


 


351
aacgcgcgcc ctcatcgtcc gcaaagaagg taaccttctt atcatcgcaa


 


401
acccttaa






This corresponds to the amino acid sequence <SEQ ID 1484; ORF 523.ng>:










g523.pep




1
MTVWFVAAVA VLIIELLTGT VYLLVVSAAL AGSGIAYGLT GSTPAAVLTA


 


51
ALLSALGIWF VHAKTAVGKV ETDSYQDLDT GKYAEILRYT GGNRYEVFYR


 


101
GTHWQAQNTG QEVFEPGTRA LIVRKEGNLL IIANP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1485>:









m523.seq (partial)










1
..GCCGTCTTAA TCATCGAATT ATTGACGGGA ACGGTTTATC TTTTGGTTGT



 


51
  nAGCGCGGCT TTGGCGGGTT CGGGCATTGC TTACGGGCTG ACCGGCAGTA


 


101
  CGCCTGCCGC CGTCTTGACC GnCGCTCTGC TTTCCGCGCT GGGTATTTnG


 


151
  TTCGTACACG CCAAAACCGC CGTTAGAAAA GTTGAAACGG ATTCATATCA


 


201
  GGATTTGGAT GCCGGACAAT ATGTCGAAAT CCTCCGACAC ACAGGCGGCA


 


251
  ACCGTTACGA AGTTTTtTAT CGCGGTACGc ACTGGCAGGC TCAAAATACG


 


301
  GGGCAAGAAG AGCTTGAACC AGGAACTCGC GCCCTCATTG TCCGCAAGGA


 


351
  AGGCAACCTT CTTATTATCA CACACCCTTA A






This corresponds to the amino acid sequence <SEQ ID 1486; ORF 523>:









m523.pep (partial)










1
..AVLIIELLTG TVYLLVVSAA LAGSGIAYGL TGSTPAAVLT XALLSALGIX



 


51
  FVHAKTAVRK VETDSYQDLD AGQYVEILRH TGGNRYEVFY RGTHWQAQNT


 


101
  GQEELEPGTR ALIVRKEGNL LIITHP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF523 shows 91.3% identity over a 126 aa overlap with a predicted ORF (ORF 523.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1487>:










a523.seq




1
ATGACTGTAT GGTTTGTTGC CGCTGTTGCC GTCTTAATCA TCGAATTATT


 


51
GACGGGAACG GTTTATCTTT TGGTTGTCAG CGCGGCTTTG GCGGGTTCGG


 


101
GCATTGCTTA CGGGCTGACC GGCAGCACGC CTGCCGCCGT CTTGACCGCC


 


151
GCTCTGCTTT CCGCGCTGGG TATTTGGTTC GTACACGCCA AAACCGCCGT


 


201
GGGAAAAGTT GAAACGGATT CATATCAGGA TTTGGATGCC GGGCAATATG


 


251
CCGAAATCCT CCGGCACGCA GGCGGCAACC GTTACGAAGT TTTTTATCGC


 


301
GGTACGCACT GGCAGGCTCA AAATACGGGG CAAGAAGAGC TTGAACCAGG


 


351
AACGCGCGCC CTAATCGTCC GCAAGGAAGG CAACCTTCTT ATCATCGCAA


 


401
AACCTTAA






This corresponds to the amino acid sequence <SEQ ID 1488; ORF 523.a>:










a523.pep




1
MTVWFVAAVA VLIIELLTGT VYLLVVSAAL AGSGIAYGLT GSTPAAVLTA


 


51
ALLSALGIWF VHAKTAVGKV ETDSYQDLDA GQYAEILRHA GGNRYEVFYR


 


101
GTHWQAQNTG QEELEPGTRA LIVRKEGNLL IIAKP*






m523/a523 94.4% identity in 126 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1489>:










g525.seq




1
atgaagtacg tccggttatt tttcctcggc acggcactcg ccggcactca


 


51
agcggcggct gccgaaatgg ttcaaatcga aggcggcagc taccgcccgc


 


101
tttatctgaa aaaagatacc ggcctgatta aagtcaaacc gttcaaactg


 


151
gataaatatc ccgttaccaa tgccgagttt gccgaatttg tcaacagcca


 


201
cccccaatgg caaaaaggca ggatcggttc caaacaggca gaacccgctt


 


251
acctgaagca ttggatgaaa aacggcagcc gcagctatgc gccgaaggcg


 


301
ggcgaattga aacagccggt taccaatatt tcctggtttg ccgccaacgc


 


351
ctattgcgcc gcacaaggca aacgcctgcc gaccatcgac gaatgggaat


 


401
ttgccggact tgcttccgcc acgcagaaaa aacggctcaa acgaacccgg


 


451
ctacaaccgc actattctcg attggtatgc cgacggcgga cggaaaggcc


 


501
tgcacgatgt cggcaaagca ccgcccgaac tactggggtg tttatgatat


 


551
gcacgggctg a






This corresponds to the amino acid sequence <SEQ ID 1490; ORF 525.ng>:










g525.pep




1
MKYVRLFFLG TALAGTQAAA AEMVQIEGGS YRPLYLKKDT GLIKVKPFKL


 


51
DKYPVTNAEF AEFVNSHPQW QKGRIGSKQA EPAYLKHWMK NGSRSYAPKA


 


101
GELKQPVTNI SWFAANAYCA AQGKRLPTID EWEFAGLASA TQKKRLKRTR


 


151
LQPHYSRLVC RRRTERPARC RQSTARTTGV FMICTG *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1491>:










m525.seq




1
ATGAAGTATG TCCGGTTATT TTwCCTCGGC GCGGCACTCG cCrrCACTCA


 


51
ArCGGCGGCT GcCGAAATGG TTCAAATCGA AGGCGGCAgC TACCGCCCrC


 


101
TTTATCTGAA AAAAGATACC GGCCTGATTA AAGTCAAACC GTTCAAACTG


 


151
GATAAATATC CCGTTACCAA TGCCGAGTTT GCCGAATTTG TCAACAGCCA


 


201
CCCCCAATGG CAAAAAGGCA GGATCGGTTC CAAACAGGCA GAACCCGCTT


 


251
ACCTGAAGCA TTGGATGAAA AACGGCAGCC GCAGCTATGc GCCGAAGgCG


 


301
GgCGAATTAA AACAACCGGT AACCAATGTT TCCTGGwTTG CCGCCAAcGC


 


351
CTAtTGCGCC GCACAAGGCA AACGCCTGCC GACCATTGAC GAATGGGAAT


 


401
TTGCCGGACT TGCTTCCGCC ACGCAGAAAA A.CGGCTCAA ACGAACCCGG


 


451
CTACAACCGC ACTATTCTCG ATTGGTATGC CGACGGCGGA CGGAAAGGCC


 


501
TGCACGATGT CGGCA.AAGG CCGCCCGAAC TACTGGGGCG TTTATGATAT


 


551
GCACGGGCTG A






This corresponds to the amino acid sequence <SEQ ID 1492; ORF 525>:










m525.pep




1
MKYVRLFXLG AALAXTQXAA AEMVQIEGGS YRPLYLKKDT GLIKVKPFKL


 


51
DKYPVTNAEF AEFVNSHPQW QKGRIGSKQA EPAYLKHWMK NGSRSYAPKA


 


101
GELKQPVTNV SWXAANAYCA AQGKRLPTID EWEFAGLASA TQKXRLKRTR


 


151
LQPHYSRLVC RRRTERPARC RXKAARTTGA FMICTG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 525 shows 94.1% identity over a 186 aa overlap with a predicted ORF (ORF 525.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1493>:










a525.seq




1
ATGAAGTTTA CCCGGTTACT CTTTCTCTGT GCGGCACTCG CCGGCACTCA


 


51
AGCGGCAGCT GCCGAAATGG TTCAAATCGA AGGCGGCAGC TACCGCCCGC


 


101
TTTATCTGAA AAAAGATACC GGCCTGATTA AAGTCAAACC GTTCAAACTG


 


151
GATAAATATC CCGTTACCAA TGCCGAGTTT GCCGAATTTG TCAACAGCCA


 


201
CCCCCAATGG CAAAAAGGCA GGATCGGTTC CAAACAGGCA GAACCCGCTT


 


251
ACCTGAAGCA TTGGATGAAA AACGGCAGCC GCAGCTATGC GCCGAAGGCG


 


301
GGCGATTTAA AACAACCGGT AACCAATGTT TCCTGGTTCG CCGCCAACGC


 


351
CTATTGCGCC GCACAAGGCA AACGCCTGCC GACCATTGAC GAATGGGAAT


 


401
TTGCCGGACT TGCCTCCGCC ACGCAG.AAA AACGGCTCAA ACGAACCCGG


 


451
CTACAACCGC ACTATTCTCG ACTGGTATGC GGATGGCGAC CGGAAAGACC


 


501
TGCACGATGT CGGCAAAG.G TCGCCCGAAC TACTGGGGCG TTTATGATAT


 


551
GCACGGTCTG A






This corresponds to the amino acid sequence <SEQ ID 1494; ORF 525.a>:










a525.pep




1
MKFTRLLFLC AALAGTQAAA AEMVQIEGGS YRPLYLKKDT GLIKVKPFKL


 


51
DKYPVTNAEF AEFVNSHPQW QKGRIGSKQA EPAYLKHWMK NGSRSYAPKA


 


101
GDLKQPVTNV SWFAANAYCA AQGKRLPTID EWEFAGLASA TQXKRLKRTR


 


151
LQPHYSRLVC GWRPERPARC RQXVARTTGA FMICTV*






m525/a525 90.8% identity in 185 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1495>:










g525-1.seq




1
ATGAAGTACG TCCGGTTATT TTTCCTCGGC ACGGCACTCG CCGGCACTCA


 


51
AGCGGCGGCT GCCGAAATGG TTCAAATCGA AGGCGGCAGC TACCGCCCGC


 


101
TTTATCTGAA AAAAGATACC GGCCTGATTA AAGTCAAACC GTTCAAACTG


 


151
GATAAATATC CCGTTACCAA TGCCGAGTTT GCCGAATTTG TCAACAGCCA


 


201
CCCCCAATGG CAAAAAGGCA GGATCGGTTC CAAACAGGCA GAACCCGCTT


 


251
ACCTGAAGCA TTGGATGAAA AACGGCAGCC GCAGCTATGC GCCGAAGGCG


 


301
GGCGAATTGA AACAGCCGGT TACCAATATT TCCTGGTTTG CCGCCAACGC


 


351
CTATTGCGCC GCACAAGGCA AACGCCTGCC GACCATCGAC GAATGGGAAT


 


401
TTGCCGGACT TGCTTCCGCC ACGCAGAAAA ACGGCTCAAA CGAACCCGGC


 


451
TACAACCGCA CTATTCTCGA TTGGTATGCC GACGGCGGAC GGAAAGGCCT


 


501
GCACGATGTC GGCAAAGACC GCCCGAACTA CTGGGGTGTT TATGATATGC


 


551
ACGGGCTGAT TTGGGAATGG ACGGAAGATT TCAACAGCAG CCTGCTTTCT


 


601
TCCGGCAATG CCAACGCGCA AATGTTTTGC AGCGGCGCAT CTGTCGGGGC


 


651
GAGCGACTCG TCCAACTATG CCGCCTTCCT CCGCTACGGC ATCCGCACCA


 


701
GCCTGCAATC CAAATACGTC CTGCACAACT TGGGCTTCCG CTGCGCAAGC


 


751
CGATAA






This corresponds to the amino acid sequence <SEQ ID 1496; ORF 525-1.ng>:










g525-1.pep




1
MKYVRLFFLG TALAGTQAAA AEMVQIEGGS YRPLYLKKDT GLIKVKPFKL


 


51
DKYPVTNAEF AEFVNSHPQW QKGRIGSKQA EPAYLKHWMK NGSRSYAPKA


 


101
GELKQPVTNI SWFAANAYCA AQGKRLPTID EWEFAGLASA TQKNGSNEPG


 


151
YNRTILDWYA DGGRKGLHDV GKDRPNYWGV YDMHGLIWEW TEDFNSSLLS


 


201
SGNANAQMFC SGASVGASDS SNYAAFLRYG IRTSLQSKYV LHNLGFRCAS


 


251
R*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1497>:










m525-1.seq




1
ATGAAGTATG TCCGGTTATT TTTCCTCGGC GCGGCACTCG CCGGCACTCA


 


51
AGCGGCGGCT GCCGAAATGG TTCAAATCGA AGGCGGCAGC TACCGCCCGC


 


101
TTTATCTGAA AAAAGATACC GGCCTGATTA AAGTCAAACC GTTCAAACTG


 


151
GATAAATATC CCGTTACCAA TGCCGAGTTT GCCGAATTTG TCAACAGCCA


 


201
CCCCCAATGG CAAAAAGGCA GGATCGGTTC CAAACAGGCA GAACCCGCTT


 


251
ACCTGAAGCA TTGGATGAAA AACGGCAGCC GCAGCTATGC GCCGAAGGCG


 


301
GGCGAATTAA AACAACCGGT AACCAATGTT TCCTGGTTTG CCGCCAACGC


 


351
CTATTGCGCC GCACAAGGCA AACGCCTGCC GACCATTGAC GAATGGGAAT


 


401
TTGCCGGACT TGCTTCCGCC ACGCAGAAAA ACGGCTCAAA CGAACCCGGC


 


451
TACAACCGCA CTATTCTCGA TTGGTATGCC GACGGCGGAC GGAAAGGCCT


 


501
GCACGATGTC GGCAAAGGCC GCCCGAACTA CTGGGGCGTT TATGATATGC


 


551
ACGGGCTGAT TTGGGAATGG ACGGAAGATT TCAACAGCAG CCTGCTTTCT


 


601
TCCGGCAATG CCAACGCGCA AATGTTTTGC AGCGGCGCGT CTATCGGGTC


 


651
GAGCGACTCG TCCAACTATG CCGCCTTCCT CCGCTACGGC ATCCGTACCA


 


701
GCCTGCAATC CAAATATGTC TTGCACAACT TGGGCTTCCG TTGCACAAGC


 


751
CGATAA






This corresponds to the amino acid sequence <SEQ ID 1498; ORF 525-1>:










m525-1.pep




1
MKYVRLFFLG AALAGTQAAA AEMVQIEGGS YRPLYLKKDT GLIKVKPFKL


 


51
DKYPVTNAEF AEFVNSHPQW QKGRIGSKQA EPAYLKHWMK NGSRSYAPKA


 


101
GELKQPVTNV SWFAANAYCA AQGKRLPTID EWEFAGLASA TQKNGSNEPG


 


151
YNRTILDWYA DGGRKGLHDV GKGRPNYWGV YDMHGLIWEW TEDFNSSLLS


 


201
SGNANAQMFC SGASIGSSDS SNYAAFLRYG IRTSLQSKYV LHNLGFRCTS


 


251
R*






m525-1/g525-1 97.6% identity in 251 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1499>:










a525-1.seq




1
ATGAAGTTTA CCCGGTTACT CTTTCTCTGT GCGGCACTCG CCGGCACTCA


 


51
AGCGGCAGCT GCCGAAATGG TTCAAATCGA AGGCGGCAGC TACCGCCCGC


 


101
TTTATCTGAA AAAAGATACC GGCCTGATTA AAGTCAAACC GTTCAAACTG


 


151
GATAAATATC CCGTTACCAA TGCCGAGTTT GCCGAATTTG TCAACAGCCA


 


201
CCCCCAATGG CAAAAAGGCA GGATCGGTTC CAAACAGGCA GAACCCGCTT


 


251
ACCTGAAGCA TTGGATGAAA AACGGCAGCC GCAGCTATGC GCCGAAGGCG


 


301
GGCGATTTAA AACAACCGGT AACCAATGTT TCCTGGTTCG CCGCCAACGC


 


351
CTATTGCGCC GCACAAGGCA AACGCCTGCC GACCATTGAC GAATGGGAAT


 


401
TTGCCGGACT TGCCTCCGCC ACGCAGAAAA ACGGCTCAAA CGAACCCGGC


 


451
TACAACCGCA CTATTCTCGA CTGGTATGCG GATGGCGACC GGAAAGACCT


 


501
GCACGATGTC GGCAAAGGTC GCCCGAACTA CTGGGGCGTT TATGATATGC


 


551
ACGGTCTGAT TTGGGAATGG ACGGAAGATT TCAACAGCAG CCTGCTTTCT


 


601
TCCGGCAATG CCAACGCGCA AATGTTTTGC AGCGGCGCGT CTATCGGGTC


 


651
GAGCGACTCG TCCAACTATG CCGCCTTCCT CCGCTACGGC ATCCGCACCA


 


701
GCCTGCAATC CAAATATGTC TTGCACAACT TGGGCTTCCG TTGCACAAGC


 


751
CGATAA






This corresponds to the amino acid sequence <SEQ ID 1500; ORF 525-1.a>:










a525-1.pep




1
MKFTRLLFLC AALAGTQAAA AEMVQIEGGS YRPLYLKKDT GLIKVKPFKL


 


51
DKYPVTNAEF AEFVNSHPQW QKGRIGSKQA EPAYLKHWMK NGSRSYAPKA


 


101
GDLKQPVTNV SWFAANAYCA AQGKRLPTID EWEFAGLASA TQKNGSNEPG


 


151
YNRTILDWYA DGDRKDLHDV GKGRPNYWGV YDMHGLIWEW TEDFNSSLLS


 


201
SGNANAQMFC SGASIGSSDS SNYAAFLRYG IRTSLQSKYV LHNLGFRCTS


 


251
R*






m525-1/a525-1 97.2% identity in 251 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1501>:










g527.seq




1
atggttttac cagtctcctt ttttcagcct gtccagttgg cggcggtcgc


 


51
gcttggtcgg tctgccgtcg ggatgggcgg aagtgatgcg gctgaattgg


 


101
tcgagctgtt tgcactcttc cctcaatgct gccgttttcg cgtcttcttc


 


151
atacagaagc cgcgcctcgg gtgccgggcg gcgttggtgg ttcaaacctt


 


201
taaccttgat tttatgggga agggaattga gcgtcaggtc gataatatcg


 


251
ccgatgtcta tggttttact gtttttgact ttcgagccgt ttacttgaac


 


301
cctacccagt tcgatatgct tttgcgcaag ggaacgggtc ttgaaaaaac


 


351
gtgccgccca aagccatttg tccagccgca tggcggaaga atcgtgcttg


 


401
tctttcatac gattttgttt gaaataattg aatttgtttc gagtttagca


 


451
taa






This corresponds to the amino acid sequence <SEQ ID 1502; ORF 527.ng>:










g527.pep




1
MVLPVSFFQP VQLAAVALGR SAVGMGGSDA AELVELFALF PQCCRFRVFF


 


51
IQKPRLGCRA ALVVQTFNLD FMGKGIERQV DNIADVYGFT VFDFRAVYLN


 


101
PTQFDMLLRK GTGLEKTCRP KPFVQPHGGR IVLVFHTILF EIIEFVSSLA


 


151
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1503>:










m527.seq




1
ATGGTTTTAC CAGTCTCCTT TTTTCAGCCT GTCCAGTTGG CGGCGGTCGC


 


51
GCTTGGTCGG TCTGCCGTCG GGATAGGCGG AAGTGATGCG GCTGAATTGG


 


101
TCGAGCTGTT TGCGCTCTTC CCTCAATGTT GCCGTTwTCG CGTCCTCTTC


 


151
ATACAGAAGC CGCGCyTCGG ATGCCGGGCG GCGTTGGTGG TTCAAACCTT


 


201
TAACCkTGAT TTTATAGGGA AGGG.AATTk AgCkTCaGTy GrTwATaTCG


 


251
CsGATGTmTA TGGTTTTACT GTTTTTGACC TTCGAGCCGT TTACTTGAAC


 


301
CCTACCCAGT TCGATGTGCT TTTGCGCAAG GGAACGGGTC TTGAAAAAAC


 


351
GTGCCGCCCA AAGCCATTTG TCCAGCCGCA TGGCGGAAGA ATCGTGCTTG


 


401
TCTTTCATAC GATTTTGTTT GAAATAATTG AATTTGTTTC GAGTTTAGCA


 


451
TAA






This corresponds to the amino acid sequence <SEQ ID 1504; ORF 527>:










m527pep




1
MVLPVSFFQP VQLAAVALGR SAVGIGGSDA AELVELFALF PQCCRXRVLF


 


51
IQKPRXGCRA ALVVQTFNXD FIGKXNXASV XXIADVYGFT VFDLRAVYLN


 


101
PTQFDVLLRK GTGLEKTCRP KPFVQPHGGR IVLVFHTILF EIIEFVSSLA


 


151
*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 527 shows 90.0% identity over a 150 aa overlap with a predicted ORF (ORF 527.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1505>:










a527.seq




1
ATGGTTTTAC CAGTCTCCTT TTTTCAGCCT GTCCAGTTGG CGGCGGTCGC


 


51
GCTTGGTCGG TCTGCCGTCG GGATAGGCGG AAGTGATGCG GCTGAATTGG


 


101
TCGAGCTGTT TGCGCTCTTC CCTCAATGTT GCCGTTTTCG CGTCCTCTTC


 


151
ATACAGAAGC CGCGCCTCGG ATGCCGGGCG GCGTTGGTGG TTCAAACCTT


 


201
TAACCTTGAT TTTATAGGGA AGGGAATTGA GCGTCAGGTC GATAATATCG


 


251
CCGATGTCTA TGGTTTTACT GTTTTTGACC TTCGAGCCGT TTACTTGAAC


 


301
CCTACCCAGT TCGATGTGCT TTTGCGCAAG GGAACGGGTC TTGAAAAAAC


 


351
GTGCCGCCCA AAGCCATTTG TCCAGCCGCA TGGCGGAAGA ATCGTGCTTG


 


401
TCTTTCATAC GATTTTGTTT GAAATAATTG AATTTGTTTC GAGTTTAGCA


 


451
TAA






This corresponds to the amino acid sequence <SEQ ID 1506; ORF 527.a>:










a527.pep




1
MVLPVSFFQP VQLAAVALGR SAVGIGGSDA AELVELFALF PQCCRFRVLF


 


51
IQKPRLGCRA ALVVQTFNLD FIGKGIERQV DNIADVYGFT VFDLRAVYLN


 


101
PTQFDVLLRK GTGLEKTCRP KPFVQPHGGR IVLVFHTILF EIIEFVSSLA


 


151
*






m527/a527 93.3% identity in 150 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1507>:










g528.seq




1
atggaaattc gggtaataaa atatacggca acggctgcgt tgtttgcatt


 


51
tacggttgca ggctgccggc tggcggggtg gtatgagtgt ttgtccttgt


 


101
ccggctggtg taagccgaga aaacctgccg ccatcgattt ttgggatatt


 


151
ggcggcgaga gtccgctgtc tttagaggac tacgagatac cgctttcaga


 


201
cggcaatcgt tccgtcaggg caaacgaata tgaatccgcg caaaaatctt


 


251
acttttatag gaaaataggg aagtttgaag cctgcgggtt ggattggcgt


 


301
acgcgtgacg gcaaaccttt ggttgagagg ttcaaacagg aaggtttcga


 


351
ctgtttggaa aagcaggggt tgcggcgcaa cggcctgtcc gagcgcgtcc


 


401
gatggtaa






This corresponds to the amino acid sequence <SEQ ID 1508; ORF 528.ng>:










g528.pep




1
MEIRVIKYTA TAALFAFTVA GCRLAGWYEC LSLSGWCKPR KPAAIDFWDI


 


51
GGESPLSLED YEIPLSDGNR SVRANEYESA QKSYFYRKIG KFEACGLDWR


 


101
TRDGKPLVER FKQEGFDCLE KQGLRRNGLS ERVRW*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1509>:









m528.seq (partial)










1
ATGGAAATTC GGGCAATAAA ATATACGGCA ATGGCTGCGT TGCTTGCATT



 


51
TACGGTTGCA GGCTGCCGGC TGGCGGGGTG GTATGAGTGT TCGTCCCTCA


 


101
CCGGCTGGTG TAAGCCGAGA AAACCGGCTG CCATCGATTT TTGGGATATT


 


151
GGCGGCGAGA GTCCGCCGTC TTTAGGGGAC TACGAGATAC CGCTTTCAGA


 


201
CGGCAATAGT TCCGTCAGGG CAAACGAATA TGAATCCGCA CAACAATCTT


 


251
ACTTTTACAG GAAAATAGGG AAGTTTGAAG C.TGCGGGCT GGATTGGCGT


 


301
ACGCGTGACG GCAAACCTTT GATTGAGACG TTCAAACAGG GAGGATTTGA


 


351
CTGCTTGGAA AAG....






This corresponds to the amino acid sequence <SEQ ID 1510; ORF 528>:










m528.pep
(partial)



1
MEIRAIKYTA MAALLAFTVA GCRLAGWYEC SSLTGWCKPR KPAAIDFWDI


 


51
GGESPPSLGD YEIPLSDGNS SVRANEYESA QQSYFYRKIG KFEXCGLDWR


 


101
TRDGKPLIET FKQGGFDCLE K....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 528 shows 89.3% identity over a 121 aa overlap with a predicted ORF (ORF 528.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1511>:










a528.seq




1
ATGGAAATTC GGGCAATAAA ATATACGGCA ATGGCTGCGT TGCTTGCATT


 


51
TACGGTTGCA GGCTGCCGGT TGGCAGGTTG GTATGAGTGT TCGTCCCTGT


 


101
CCGGCTGGTG TAAGCCGAGA AAACCTGCCG CCATCGATTT TTGGGATATT


 


151
GGCGGCGAGA GTCCTCCGTC TTTAGAGGAC TACGAGATAC CGCTTTCAGA


 


201
CGGCAATCGT TCCGTCAGGG CAAACGAATA TGAATCCGCA CAACAATCTT


 


251
ACTTTTACAG GAAAATAGGG AAGTTTGAAG CCTGCGGGTT GGATTGGCGT


 


301
ACGCGTGACG GCAAACCTTT GATTGAGACG TTCAAACAGG AAGGTTTTGA


 


351
TTGTTTGAAA AAGCAGGGGT TGCGGCGCAA CGGTCTGTCC GAGCGCGTCC


 


401
GATGGTAA






This corresponds to the amino acid sequence <SEQ ID 1512; ORF 528.a>:










a528.pep




1
MEIRAIKYTA MAALLAFTVA GCRLAGWYEC SSLSGWCKPR KPAAIDFWDI


 


51
GGESPPSLED YEIPLSDGNR SVRANEYESA QQSYFYRKIG KFEACGLDWR


 


101
TRDGKPLIET FKQEGFDCLK KQGLRRNGLS ERVRW*






m528/a528 95.0% identity in 121 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1513>:










g528-1.seq




1
ATGGAAATTC GGGTAATAAA ATATACGGCA ACGGCTGCGT TGTTTGCATT


 


51
TACGGTTGCA GGCTGCCGGC TGGCGGGGTG GTATGAGTGT TCGTCCTTGT


 


101
CCGGCTGGTG TAAGCCGAGA AAACCTGCCG CCATCGATTT TTGGGATATT


 


151
GGCGGCGAGA GTCCGCTGTC TTTAGAGGAC TACGAGATAC CGCTTTCAGA


 


201
CGGCAATCGT TCCGTCAGGG CAAACGAATA TGAATCCGCG CAAAAATCTT


 


251
ACTTTTATAG GAAAATAGGG AAGTTTGAAG CCTGCGGGTT GGATTGGCGT


 


301
ACGCGTGACG GCAAACCTTT GGTTGAGAGG TTCAAACAGG AAGGTTTCGA


 


351
CTGTTTGGAA AAGCAGGGGT TGCGGCGCAA CGGCCTGTCC GAGCGCGTCC


 


401
GATGGTAA






This corresponds to the amino acid sequence <SEQ ID 1514; ORF 528-1.ng>:










g528-1.pep




1
MEIRVIKYTA TAALFAFTVA GCRLAGWYEC SSLSGWCKPR KPAAIDFWDI


 


51
GGESPLSLED YEIPLSDGNR SVRANEYESA QKSYFYRKIG KFEACGLDWR


 


101
TRDGKPLVER FKQEGFDCLE KQGLRRNGLS ERVRW*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1515>:










m528-1.seq




1
ATGGAAATTC GGGCAATAAA ATATACGGCA ATGGCTGCGT TGCTTGCATT


 


51
TACGGTTGCA GGCTGCCGGC TGGCGGGGTG GTATGAGTGT TCGTCCCTCA


 


101
CCGGCTGGTG TAAGCCGAGA AAACCGGCTG CCATCGATTT TTGGGATATT


 


151
GGCGGCGAGA GTCCGCCGTC TTTAGGGGAC TACGAGATAC CGCTTTCAGA


 


201
CGGCAATCGT TCCGTCAGGG CAAACGAATA TGAATCCGCA CAACAATCTT


 


251
ACTTTTACAG GAAAATAGGG AAGTTTGAAG CCTGCGGGCT GGATTGGCGT


 


301
ACGCGTGACG GCAAACCTTT GATTGAGACG TTCAAACAGG GAGGATTTGA


 


351
CTGCTTGGAA AAGCAGGGGT TGCGGCGCAA CGGTCTGTCC GAGCGCGTCC


 


401
GATGGTAA






This corresponds to the amino acid sequence <SEQ ID 1516; ORF 528-1>:










m528-1.pep..




1
MEIRAIKYTA MAALLAFTVA GCRLAGWYEC SSLTGWCKPR KPAAIDFWDI


 


51
GGESPPSLGD YEIPLSDGNR SVRANEYESA QQSYFYRKIG KFEACGLDWR


 


101
TRDGKPLIET FKQGGFDCLE KQGLRRNGLS ERVRW*






g528-1/m528-1 92.6% identity in 135 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1517>:










a528-1.seq




1
ATGGAAATTC GGGCAATAAA ATATACGGCA ATGGCTGCGT TGCTTGCATT


 


51
TACGGTTGCA GGCTGCCGGT TGGCAGGTTG GTATGAGTGT TCGTCCCTGT


 


101
CCGGCTGGTG TAAGCCGAGA AAACCTGCCG CCATCGATTT TTGGGATATT


 


151
GGCGGCGAGA GTCCTCCGTC TTTAGAGGAC TACGAGATAC CGCTTTCAGA


 


201
CGGCAATCGT TCCGTCAGGG CAAACGAATA TGAATCCGCA CAACAATCTT


 


251
ACTTTTACAG GAAAATAGGG AAGTTTGAAG CCTGCGGGTT GGATTGGCGT


 


301
ACGCGTGACG GCAAACCTTT GATTGAGACG TTCAAACAGG AAGGTTTTGA


 


351
TTGTTTGAAA AAGCAGGGGT TGCGGCGCAA CGGTCTGTCC GAGCGCGTCC


 


401
GATGGTAA






This corresponds to the amino acid sequence <SEQ ID 1518; ORF 528-1.a>:










a528-1.pep




1
MEIRAIKYTA MAALLAFTVA GCRLAGWYEC SSLSGWCKPR KPAAIDFWDI


 


51
GGESPPSLED YEIPLSDGNR SVRANEYESA QQSYFYRKIG KFEACGLDWR


 


101
TRDGKPLIET FKQEGFDCLK KQGLRRNGLS ERVRW*






a528-1/m528-1 97.0% identity in 135 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1519>:










g529.seq
(partial)



1
atgacccata tcaaacccgt cattgccgcg ctcgcactca tcgggcttgc


 


51
cgcctgctcc ggcagcaaaa ccgaacagcc caagctcgac taccaaagcc


 


101
ggtcgcaccg cctgatcaaa ctcgaagtcc cgcctgattt gaacaacccc


 


151
gaccaaggca acctctaccg cctgcctgcc ggttcgggag ccgtccgcgc


 


201
cggggatttg gaaaaacgcc gcacacccgc cgtccaacag ccagcggatg


 


251
ccggaagtat tgaaaagcgt caaaggcgtc cgcttcgagc ggcgacggca


 


301
gccaacgcct ggcttgtcgt tgacggcaaa tcccccgccg aaatctccgc


 


351
cgctttctg.






This corresponds to the amino acid sequence <SEQ ID 1520; ORF 529.ng>:










g529.pep
(partial)



1
MTHIKPVIAA LALIGLAACS GSKTEQPKLD YQSRSHRLIK LEVPPDLNNP


 


51
DQGNLYRLPA GSGAVRAGDL EKRRTPAVQQ PADAGSIEKR QRRPLRAATA


 


101
ANAWLVVDGK SPAEISAAF..






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1521>:










m529.seq




1
ATGACCCATA TCAAACCCGT CATTGCCGCG CTCGCACTCA TCGGGCTTGC


 


51
CGCCTGCTCC GGCAGCAAAA CCGAACAGCC CAAGCTCGAC TACCAAAGCC


 


101
GGTCGCACCG CCTGATCAAA CTTGAAGTCC CACCTGATTT GAAAAACGCC


 


151
GACCAAGGCA ACCTCTACCG CCTGCCTGCC GGTTCGGGCG CCGTCCGCGC


 


201
CAGCGATTTG GAAAAACGCC GCACACCCGC CGTCCAACAG CCTGCCGATG


 


251
CCGAAGTATT GAAAAGCGTC AAAGGTGTCC GCCTCGAGCG CGACGGCAGC


 


301
CAACGCTGGC TCGTTGTCGA CGGCAAGTCT CCTGCCGAAA TCTGGCCGCT


 


351
CCTGAAAGCC TTTTGGCAGG AAAACGGCTT CGACATCAAA TCCGAAGAAC


 


401
CCGCCATCGG ACAAATGGAA ACCGAGTGGG CGGAAAACCG CGCCAAAATC


 


451
CCCCAAGACA GCTTGCGCCG CCTCTTCGAC AAAGTCGGCT TGGGCGGCAT


 


501
CTACTCCACC GGCGAGCGCG ACAAATTCAT CGTCCGTATC GAACAGGGCA


 


551
AAAACGGCGT TTCCGACATC TTCTTCGCCC ACAAAGCCAT GAAAGAAGTG


 


601
TACGGCGGCA AAGACAAAGA CACGACCGTA TGGCAGCCCT CCCCGTCCGA


 


651
TCCCAACCTC GAAGCCGCTT TCCTGACGCG CTTTATGCAA TATTTGGGCG


 


701
TTGACGGACA GCAGGCGGAA AACGCATCGG CAAAAAAACC TACCCTTCCC


 


751
GCCGCCAACG AAATGGCGCG TATCGAAGGC AAAAGCCTGA TTGTCTTTGG


 


801
CGACTACGGC AGAAACTGGC GGCGCACCGT GCTCGCCCTC GACCGCATCG


 


851
GGCTGACCGT CGTCGGTCAA AACACCGAAC GCCACGCCTT CCTGGTTCAA


 


901
AAAGCCCCGA ACGAAAGCAA TGCAGTTACC GAACAAAAAC CCGGCCTGTT


 


951
CAAACGCCTG CTGGGCAAAG GCAAAGCGGA GAAACCTGCC GAACAGCCGG


 


1001
AACTGATTGT CTATGCAGAA CCTGTCGCCA ACGGCTCGCG CATCGTCCTG


 


1051
CTCAACAAAG ACGGCAGCGC ATATGCCGGC AAAGACGCAT CCGCATTATT


 


1101
GGGCAAACTC CATTCCGAAC TGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1522; ORF 529>:










m529.pep




1
MTHIKPVIAA LALIGLAACS GSKTEQPKLD YQSRSHRLIK LEVPPDLNNP


 


51
DQGNLYRLPA GSGAVRASDL EKRRTPAVQQ PADAEVLKSV KGVRLERDGS


 


101
QRWLVVDGKS PAEIWPLLKA FWQENGFDIK SEEPAIGQME TEWAENRAKI


 


151
PQDSLRRLFD KVGLGGIYST GERDKFIVRI EQGKNGVSDI FFAHKAMKEV


 


201
YGGKDKDTTV WQPSPSDPNL EAAFLTRFMQ YLGVDGQQAE NASAKKPTLP


 


251
AANEMARIEG KSLIVFGDYG RNWRRTVLAL DRIGLTVVGQ NTERHAFLVQ


 


301
KAPNESNAVT EQKPGLFKRL LGKGKAEKPA EQPELIVYAE PVANGSRIVL


 


351
LNKDGSAYAG KDASALLGKL HSELR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 529 shows 83.5% identity over a 115 aa overlap with a predicted ORF (ORF 529.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1523>:










a529.seq




1
ATGACCCATA TCAAACCCGT CATTGCCGCG CTCGCACTCA TCGGGCTTGC


 


51
CGCCTGCTCC GGCAGCAAAA CCGAACAGCC CAAGCTCGAC TACCAAAGCC


 


101
GGTCGCACCG CCTGATCAAA CTCGAAGTCC CACCTGATTT GAAAAACGCC


 


151
GACCAAGGCA ACCTCTACCG CCTGCCTGCC GGTTCGGGCG CCGTCCGCGC


 


201
CAGCGATTTG GAAAAACGCC GCACACCCGC CGTCCAACAG CCTGCCGATG


 


251
CCGAAGTATT GAAAAGCGTC AAAGGTGTCC GCCTCGAGCG CGACGGCAGC


 


301
CAACGCTGGC TCGTTGTCGA CGGCAAGTCT CATGCCGAAA TCTGGCCGCT


 


351
CCTGAAAGCC TTTTGGCAGG AAAACGGCTT CGACATCAAA TCCGAAGAAC


 


401
CCGCCATCGG ACAAATGGAA ACCGAGTGGG CGGAAAACCG TGCCAAAATC


 


451
CCCCAAGACA GCTTGCGCCG CCTATTCGAC ACAGTCGGTT TGGGCGGCAT


 


501
CTACTCCACC GGCGAGCGCG ACAAATTCAT CGTCCGTATC GAACAGGGCA


 


551
AAAACGGCGT TTCCGACATC TTCTTCGCCC ACAAAGCCAT GAAAGAAGTG


 


601
TACGGCGGCA AAGACAAAGA CACGACCGTA TGGCAGCCCT CCCCGTCCGA


 


651
TCCCAACCTC GAAGCCGCTT TCCTGACGCG CTTTATGCAA TATTTGGGCG


 


701
TTGACGGACA GCAGGCGGAA AACGCATCGG CAAAAAAACC TACCCTTCCC


 


751
GCCGCCAACG AAATGGCGCG TATCGAAGGC AAAAGCCTGA TTGTCTTTGG


 


801
CGACTACGGC AGAAACTGGC GGCGCACCGC GCTCGCCCTC GACCGCATCG


 


851
GGCTGACCGT CGTCGGTCAA AACACCGAAC GCCACGCTTT CCTGGTTCAA


 


901
AAAGCCCCGA ACGAAAGCAA TGCAGTTACC GAACAAAAAC CCGGCCTGTT


 


951
CAAACGCCTG CTGGGCAAAG GCAAAGCGGA GAAACCTGCC GAACAGCCGG


 


1001
AACTGATTGT CTATGCCGAG CCTGTCGCCA ACGGCTCGCG CATCGTCCTG


 


1051
CTCAACAAAG ACGGCAGCGC ATATGCCGGC AAAGACGCAT CCGCATTATT


 


1101
GGGCAAACTC CATTCCGAAC TGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1524; ORF 529.a>:










a529.pep




1
MTHIKPVIAA LALIGLAACS GSKTEQPKLD YQSRSHRLIK LEVPPDLNNP


 


51
DQGNLYRLPA GSGAVRASDL EKRRTPAVQQ PADAEVLKSV KGVRLERDGS


 


101
QRWLVVDGKS HAEIWPLLKA FWQENGFDIK SEEPAIGQME TEWAENRAKI


 


151
PQDSLRRLFD TVGLGGIYST GERDKFIVRI EQGKNGVSDI FFAHKAMKEV


 


201
YGGKDKDTTV WQPSPSDPNL EAAFLTRFMQ YLGVDGQQAE NASAKKPTLP


 


251
AANEMARIEG KSLIVFGDYG RNWRRTALAL DRIGLTVVGQ NTERHAFLVQ


 


301
KAPNESNAVT EQKPGLFKRL LGKGKAEKPA EQPELIVYAE PVANGSRIVL


 


351
LNKDGSAYAG KDASALLGKL HSELR*






m529/a529 99.2% identity in 375 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1525>:










g530.seq




1
atgagtgcga gcgcggcaat gacgggtttg atatgggtca tcgtgtcatc


 


51
ctgtgtgatg gatattaaag tgtttgtcat gttatgccgt ccgaacggtt


 


101
cagacggcat ggctatattt aaagttgtcc tgaggctttc agggcggcgc


 


151
ggacttttgc ctgtccgcct tccgtcagcg gaacgagcgg caggcgcacg


 


201
tgcggtccgc atccgcccaa ggcggatacc gcccatttcg gtgcggcggg


 


251
actgggttcg cagaacatgg tgtcgtaaat cggaatcagc cggtcgttga






This corresponds to the amino acid sequence <SEQ ID 1526; ORF 530.ng>:










g530.pep




1
MSASAAMTGL IWVIVSSCVM DIKVFVMLCR PNGSDGMAIF KVVLRLSGRR


 


51
GLLPVRLPSA ERAAGARAVR IRPRRIPPIS VRRDWVRRTW CRKSESAGR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1527>:










m530.seq




1
wTGAGTGCGA GCGCGGCAAT GACGGGTyTG ATATGGGTCA TCGTGTCATC


 


51
sTGTGTGATG GATATTAAAG TGTyTGTTGC GwTATGCCGT CCGAACGGTT


 


101
CGGACGGCAT GGmTATATTT AAAGTTGTCC TGAGGCTTTC AGGGCGGCGC


 


151
GGACTkTTGC wTGTCCGTTT yCCGTCAGCG GAACGAGCGG CAGGCGGACG


 


201
TGCGGTTCGC ATCTGCCCAg GGCGGATACC GCCCATTTCG GTGCGGCGGG


 


251
GCTGGGTTCG CAGAACATGG TGTCGTAAAT CGGAATCAGT CGGTCGTTGA






This corresponds to the amino acid sequence <SEQ ID 1528; ORF 530>:










m530.pep




1
XSASAAMTGL IWVIVSSCVM DIKVXVAXCR PNGSDGMXIF KVVLRLSGRR


 


51
GLLXVRFPSA ERAAGGRAVR ICPGRIPPIS VRRGWVRRTW CRKSESVGR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 530 shows 88.8% identity over a 98 aa overlap with a predicted ORF (ORF 530.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1529>:










a530.seq




1
ATGAGTGCGA GCGCGGCAAT GACGGGTTTG ATATGGGTCA TCGTGTCATC


 


51
CTGTGTGATG GATATTAAAG TGTTTGTTGC GTTATGCCGT CCGAACGGTT


 


101
CGGACGGCAT GGCTATATTT AAAGTTGTCC TGAGGCTTTC AGGGCGGCGC


 


151
GGACTTTTGC CTGTCCGCCT TCCGTCAGCG GAACGAGCGG CAGGCGGACG


 


201
TGCGGTTCGC ATCTGCCCAG GGCGGATACC GCCCATTTCG GTGCGGCGGG


 


251
GCTGGGTTCG CAGAACATGG TGTCGTAAAT CGGAATCAGC CGGTCGTTGA






This corresponds to the amino acid sequence <SEQ ID 1530; ORF 530.a>:










a530.pep




1
MSASAAMTGL IWVIVSSCVM DIKVFVALCR PNGSDGMAIF KVVLRLSGRR


 


51
GLLPVRLPSA ERAAGGRAVR ICPGRIPPIS VRRGWVRRTW CRKSESAGR*






m530/a530 93.9% identity in 98 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1531>:










g531.seq




1
ATGACCGCCC TACTCGTCAT CCTCGCCCTC GCCCTGATAG CCGTCGGCAC


 


51
GGCAGGCATC GTCTATCCCG CCCTGCCCGG CTTGGCATTG ATGTTTGCCG


 


101
GAACATGGCT GCTTGCCTAT GCCGGCGGCT ATCAAATCTA CGGCGCAGGC


 


151
ATCTTGTGGA CGGTCGGACT CATCAGCCTT GGCGGCATAC TGGCGGACTA


 


201
TATGGCAGGC ATGTTGGGGG TAAAATACAC TGGGGCAGGC AAACTCGCCG


 


251
TCCGAGGTGC ATTGGCCGGC AGCATCATCG GCATATTTTT CTCCCTTCCC


 


301
GGACTAATAC TCGGCCCCTT TATCGGCGCG GCGGCAGGCG AACTGATCGA


 


351
TCGGCGCAAT ATGCTTCAGG CAGGTAAAGC GGGCTTGGGT ACGCTGTTGG


 


401
GGCTTGTCGT CGGCACGGCG TTCAAAATCG GCTGCGCCGT ATCCATCTTG


 


451
TTTATCCTGT TGGTGAAATA CATCGCATAC CTGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 1532; ORF 531.ng>:










g531.pep




1
MTALLVILAL ALIAVGTAGI VYPALPGLAL MFAGTWLLAY AGGYQIYGAG


 


51
ILWTVGLISL GGILADYMAG MLGVKYTGAG KLAVRGALAG SIIGIFFSLP


 


101
GLILGPFIGA AAGELIDRRN MLQAGKAGLG TLLGLVVGTA FKIGCAVSIL


 


151
FILLVKYIAY LF






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1533>:










m531.seq




1
ATGACCGTAC TGACCGTCAT CCTCGCCCTC GCCCTGATAG CCGTCGGCAC


 


51
GGCGGGCATC GTTTaCCCCG CCCTGCCCGG ATTGGCATTG ATGTTTGCCG


 


101
GAACATGGCT GCTTGCCTAT GCCGGCGGCT ACCAAATCTA CGGCGCGGGC


 


151
GTTTTGTGGA CGGTCGGACT CATCAGCCTT GCCGGCATAC TGGCGGACTA


 


201
TGTGGCAGGC ATATGGGGGA CAAAATATAC CGGAGCGGGC AAGCTCGCCG


 


251
TTCGCGGCGC ATTGGCCGGC AGCATCATCG GCATATTTTT CTCCCTTCCC


 


301
GGACTAATAC TCGGTCCCTT TATCGGCGCG GCGGCAGGCG AACTGATCGA


 


351
ACGGCGCAAT ATGCTTCAGG CAGGTAAAGC GGGCTTGGGT ACGCTGTTGG


 


401
GGCTTGTCGT CGGCACGGCG TTCAAAATCG GCTGCGCnGT ATCCATCTTG


 


451
TTTATCCTGT TGGTGAaATA CATCGCCTAC CTGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 1534; ORF 531>:










m531.pep




1
MTVLTVILAL ALIAVGTAGI VYPALPGLAL MFAGTWLLAY AGGYQIYGAG


 


51
VLWTVGLISL AGILADYVAG IWGTKYTGAG KLAVRGALAG SIIGIFFSLP


 


101
GLILGPFIGA AAGELIERRN MLQAGKAGLG TLLGLVVGTA FKIGCAVSIL


 


151
FILLVKYIAY LF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 531 shows 94.4% identity over a 162 aa overlap with a predicted ORF (ORF 531.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1535>:










a531.seq




1
ATGACCGCCT TGCTCGTCAT CCTCGCCCTC GCCCTGATAG CCGCCGGTAC


 


51
GGCGGGCATC GTTTACCCCG CCCTGCCCGG ATTGGCATTG ATGTTTGCCG


 


101
GAACCTGGCT GCTCGCCTAC TCCGGCGGCT ACCAAATCTA CGGCGCGGGC


 


151
GTTTTGTGGA CGGTCGGACT CATCAGCCTT GCCGGCATAC TGGCGGACTA


 


201
TGTGGCAGGC ATATGGGGGA CAAAATATAC CGGAGCGGGC AAGCTCGCCG


 


251
TTCGCGGCGC ATTGGCCGGC AGCATCATCG GCATATTTTT CTCCCTTCCC


 


301
GGACTAATAC TCGGTCCCTT TATCGGCGCG GCGGCAGGCG AACTGATCGA


 


351
ACGGCGCAAT ATGCTTCAGG CAGGTAAAGC GGGCTTGGGT ACGCTGTTGG


 


401
GGCTTATCGT CGGTACGGCG TTCAAAATCG GCTGCGCCGT ATCCATCTTG


 


451
TTTATCCTGT TGGTGAAATA CATCGCCTAC CTGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 1536; ORF 531.a>:










a531.pep




1
MTALLVILAL ALIAAGTAGI VYPALPGLAL MFAGTWLLAY SGGYQIYGAG


 


51
VLWTVGLISL AGILADYVAG IWGTKYTGAG KLAVRGALAG SIIGIFFSLP


 


101
GLILGPFIGA AAGELIERRN MLQAGKAGLG TLLGLIVGTA FKIGCAVSIL


 


151
FILLVKYIAY LF*






m531/a531 96.9% identity in 162 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1537>:









g532.seq (partial)










1
atggctgaaa caatgaaaaa acaggcggat tcgcctgatt tggtgtacgg



 


51
tttggaagac aggccgccgt tcggtaatgc gctcttgagc gcggttaccc


 


101
atcttttggc gattttcgtg ccgatgatta cgcccgcgct gattgtgggc


 


151
ggcgcgctgg aattgccggt ggagatgacg gcgtatctgg tgtcgatggc


 


201
gatggttgcg tcgggtgtcg gcacttattt gcaggtcaac cgcttcgggt


 


251
cggtcggctc ggggatgctg tccatccagc gttaccgtca tgattgcgct


 


301
cggcgcgggg atgaaagagg gcggtttgag ...






This corresponds to the amino acid sequence <SEQ ID 1538; ORF 532.ng>:









g532.pep (partial)










1
MAETMKKQAD SPDLVYGLED RPPFGNALLS AVTHLLAIFV PMITPALIVG



 


51
GALELPVEMT AYLVSMAMVA SGVGTYLQVN RFGSVGSGML SIQRYRHDCA


 


101
RRGDERGRFE ...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1539>:










m532.seq




1
ATGAGCGGTC AGTTGGGCAA AGGTGCGGAT GCGCCTGATT TGGTGTACGG


 


51
TTTGGAAGAC AGGCCGCCGT TCGGTAATGC GCTCTTGAGC GCGGTTACCC


 


101
ATCTTTTGGC GATTTTTGTG CCGATGATTA CGCCCGCGCT GATTGTGGGC


 


151
GGCGCGCTGG AATTGCCGGT GGAGATGACG GCGTATCTCG TGTCGATGGC


 


201
GATGGTTGCG TCGGGTGTCG GCACTTATTT GCAGGTCAAC CGCTTCGGGC


 


251
CGGTCGGTTC GGGGATGCTG TCCATCCAGT CGGTGAATTT TTCGTTCGTT


 


301
ACCGTGATGA TTGCGCTGGG CGCGGGGATG AAAGAGGGCG GTTTGACTAA


 


351
GGATGCGATG ATTTCGACGC TCTTGGGCGT ATCGTTTGTC GGCGCGTTTT


 


401
TGGTGTGTTT CTCGGCGTGG CTTCTGCCGT ATTTGAAAAA AGTGATTACG


 


451
CCGACGGTCA GCGGCGTGGT CGTGATGCTC ATTGGTTTGA GTTTGGTACA


 


501
CGTCGGCATT ACCGATTTCG GCGGCGGCTT CGGCGCGAAG GCGGACGGCA


 


551
CGTTCGGCTC GATGGAAAAC TTGGGGCTGG CATCGCTGGT GTTGCTGATT


 


601
GTGTTGGTGT TCAACTGCAT GAAAAACCCG CTGTTGCGCA TGAGCGGCAT


 


651
TGCGGTCGGG CTGATTGCCG GCTATATCGT CGCGCTGTTT TTGGGCAAGG


 


701
TGGATTTTTC CGCGCTGCAA AACCTGCCGC TGGTTACGCT GCCCGTACCG


 


751
TTTAAATACG GTTTTGCTTT CGACTGGCAC GCGTTTATTG TGGCGGGCGC


 


801
GATTTTCTTG TTGAGCGTGT TTGAGGCGGT CGGCGATTTA ACCGCGACGG


 


851
CAATGGTGTC CGACCAGCCG ATTGAAGGCG AGGAATACAC CAAACGCCTG


 


901
CGCGGCGGCG TGTTGGCTGA CGGCTTGGTG TCGGTGATTG CGACGGCTTT


 


951
GGGTTCGCTG CCGCTGACGA CGTTTGCGCA AAACAACGGC GTGATTCAGA


 


1001
TGACCGGCGT GGCTTCGCGC CATGTGGGCA AATATATTGC CGTGATTTTG


 


1051
GTGCTGTTGG GTCTGTTCCC CGTTGTCGGT CGCGCGTTTA CGACGATTCC


 


1101
GAGTCCGGTG TTGGGCGGCG CGATGGTTTT GATGTTCGGC TTAATTGCGA


 


1151
TTGCGGGCGT GCGGATTTTG GTCAGTCACG GCATCCGCAG GCGCGAAGCG


 


1201
GTGATTGCGG CAACGTCGGT CGGTTTGGGC TTGGGTGTCG CGTTTGAGCC


 


1251
GGAAGTGTTT AAAAACCTGC CCGTCTTGTT CCAAAACTCT ATTTCCGCCG


 


1301
GCGGCATTAC GGCAGTCTTG CTGAATTTGG TCTTGCCCGA AGATAAAACC


 


1351
GAGGCGGCGG TCAAGTTTGA TACCGACCAC TTGGAACACT GA






This corresponds to the amino acid sequence <SEQ ID 1540; ORF 532>:










m532.pep




1
MSGQLGKGAD APDLVYGLED RPPFGNALLS AVTHLLAIFV PMITPALIVG


 


51
GALELPVEMT AYLVSMAMVA SGVGTYLQVN RFGPVGSGML SIQSVNFSFV


 


101
TVMIALGAGM KEGGLTKDAM ISTLLGVSFV GAFLVCFSAW LLPYLKKVIT


 


151
PTVSGVVVML IGLSLVHVGI TDFGGGFGAK ADGTFGSMEN LGLASLVLLI


 


201
VLVFNCMKNP LLRMSGIAVG LIAGYIVALF LGKVDFSALQ NLPLVTLPVP


 


251
FKYGFAFDWH AFIVAGAIFL LSVFEAVGDL TATAMVSDQP IEGEEYTKRL


 


301
RGGVLADGLV SVIATALGSL PLTTFAQNNG VIQMTGVASR HVGKYIAVIL


 


351
VLLGLFPVVG RAFTTIPSPV LGGAMVLMFG LIAIAGVRIL VSHGIRRREA


 


401
VIAATSVGLG LGVAFEPEVF KNLPVLFQNS ISAGGITAVL LNLVLPEDKT


 


451
EAAVKFDTDH LEH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF532 shows 91.4% identity over a 93 aa overlap with a predicted ORF (ORF 532.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1541>:










a532.seq




1
ATGAGCGGTC AGTTGGGCAA AGGTGCGGAT GCGCCTGATT TGGTGTACGG


 


51
TTTGGAGGAT AGGCCGCCGT TCGGTAATGC GCTCTTGAGC GCGGTTACCC


 


101
ATCTTTTGGC GATTTTTGTG CCGATGATTA CGCCCGCGCT GATTGTGGGC


 


151
GGCGCGCTGG AATTGCCGGT GGAGATGACG GCGTATCTCG TGTCGATGGC


 


201
GATGGTTGCG TCGGGTGTCG GCACTTATTT GCAGGTCAAC CGCTTCGGGC


 


251
CGGTCGGTTC GGGGATGCTG TCCATCCAGT CGGTGAATTT CTCGTTCGTT


 


301
ACCGTCATGA TTGCGCTCGG CGCGGGGATG AAAGAGGGCG GTTTGACTAA


 


351
GGATGCGATG ATTTCGACGC TCTTGGGCGT ATCGTTTGTC GGCGCGTTTT


 


401
TGGTGTGTTT TTCGGCGTGG CTTCTGCCGT ATTTGAAAAA AGTGATTACG


 


451
CCGACGGTCA GCGGTGTGGT GGTGATGCTG ATCGGCTTGA GTTTGGTACA


 


501
CGTCGGTATT ACCGATTTCG GCGGCGGCTT CGGCGCAAAG GCGGACGGCA


 


551
CGTTCGGCTC GATGGAAAAC TTGGGGCTGG CATCGCTGGT GCTGCTGATT


 


601
GTGCTGGTGT TCAATTGCAT GAAAAACCCG CTGCTGCGGA TGAGCGGCAT


 


651
TGCGGTCGGT CTGATTGCCG GCTATATCGT CGCGCTGTTT TTGGGCAAGG


 


701
TGGATTTTTC GGCACTGCAA AACCTGCCGC TGGTTACGCT GCCCGTACCG


 


751
TTTAAATATG GTTTTGCTTT TGACTGGCAC GCATTTATTG TGGCGGGTGC


 


801
GATTTTCTTG TTGAGCGTGT TTGAGGCGGT CGGCGATTTG ACGGCGACGG


 


851
CAATGGTGTC CGACCAGCCG ATTGAAGGCG AGGAATACAC CAAACGCTTG


 


901
CGCGGCGGCG TGTTGGCGGA CGGCTTGGTG TCGGTGATTG CGACGGCTTT


 


951
GGGTTCGCTG CCGCTGACGA CGTTTGCACA AAACAACGGC GTGATTCAGA


 


1001
TGACCGGCGT GGCTTCGCGC CATGTGGGCA AATATATTGC CGTGATTTTG


 


1051
GTGCTGTTGG GTCTGTTCCC CGTTGTCGGA CGCGCGTTTA CGACGATTCC


 


1101
GAGTCCGGTG TTGGGCGGCG CGATGGTTTT GATGTTCGGC TTGATTGCGA


 


1151
TTGCGGGCGT GCGGATTTTG GTCAGCCACG GCATCCGCAG GCGCGAAGCG


 


1201
GTAATTGCGG CAACGTCGGT CGGTTTGGGC TTGGGTGTCG CGTTTGAGCC


 


1251
GGAAGTGTTT AAAAACCTGC CCGTCTTGTT CCAAAACTCT ATTTCCGCCG


 


1301
GCGGCATTAC GGCAGTCTTG CTGAATTTGG TCTTGCCCGA AGATAAAACC


 


1351
GAGGCGGCGG TCAAGTTTGA TACCGACCAC TTGGAACACT GA






This corresponds to the amino acid sequence <SEQ ID 1542; ORF 532.a>:










a532.pep




1
MSGQLGKGAD APDLVYGLED RPPFGNALLS AVTHLLAIFV PMITPALIVG


 


51
GALELPVEMT AYLVSMAMVA SGVGTYLQVN RFGPVGSGML SIQSVNFSFV


 


101
TVMIALGAGM KEGGLTKDAM ISTLLGVSFV GAFLVCFSAW LLPYLKKVIT


 


151
PTVSGVVVML IGLSLVHVGI TDFGGGFGAK ADGTFGSMEN LGLASLVLLI


 


201
VLVFNCMKNP LLRMSGIAVG LIAGYIVALF LGKVDFSALQ NLPLVTLPVP


 


251
FKYGFAFDWH AFIVAGAIFL LSVFEAVGDL TATAMVSDQP IEGEEYTKRL


 


301
RGGVLADGLV SVIATALGSL PLTTFAQNNG VIQMTGVASR HVGKYIAVIL


 


351
VLLGLFPVVG RAFTTIPSPV LGGAMVLMFG LIAIAGVRIL VSHGIRRREA


 


401
VIAATSVGLG LGVAFEPEVF KNLPVLFQNS ISAGGITAVL LNLVLPEDKT


 


451
EAAVKFDTDH LEH*






m532/a532 100.0% identity in 463 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1543>:










g535.seq




1
atgccctttc ccgttttcag acaantattt gcttngtcct tgctacggtt


 


51
ttttgccgta ggtcggattc tcgaatccga catttccaac agcggttttt


 


101
cggaaacgat aaacgcgtca aatgtttttt ttgtcggata cgaatatccg


 


151
gcctgcattt caaatttaca tcgcttccaa tttcgcaaac ttggtatcca


 


201
gttctttcac gccctgtttg ccgaagttga tggtcagtcg ggcggattcg


 


251
cctttgtctg cggcatcgat aatcacgccg gtgccgaatt tggcgtgacg


 


301
gacgttttgt ccgatgcgga agcctgcgta ggtttgcggc tgtttgaagt


 


351
catcgatgat tttgtcccgt tgtacggtgg tttggcgcgt gttgccgtag


 


401
ctgtcgaagg cgggtttttt gacggacagg tagtgcaata cttctggcgg


 


451
gatttcttcg acgaagcggg atgcgatgcc gaattgggtt tgtccgtgca


 


501
gcatgcgttg ctgtgccatg gtgatgtaga ggcgtttgcg ggcgcgggtg


 


551
atggcgacgt acatgaggcg gcgttcttct tcgaggccgc cgcgctcggc


 


601
aaggctcatt tcgctgggga aacgcccctc ttccataccg gtgaggaaga


 


651
cggcgttgaa ttccaagcct ttggcggcgt ggacggtcat cagttggacg


 


701
gctttttcgc ctgcccctgc ttggttttcg ccggattcga gggcggcgtt


 


751
gctcaagaag gcgaggatgg ggaaggcggg atcgtctga






This corresponds to the amino acid sequence <SEQ ID 1544; ORF 535.ng>:










g535.pep




1
MPFPVFRQXF AXSLLRFFAV GRILESDISN SGFSETINAS NVFFVGYEYP


 


51
ACISNLHRFQ FRKLGIQFFH ALFAEVDGQS GGFAFVCGID NHAGAEFGVT


 


101
DVLSDAEACV GLRLFEVIDD FVPLYGGLAR VAVAVEGGFF DGQVVQYFWR


 


151
DFFDEAGCDA ELGLSVQHAL LCHGDVEAFA GAGDGDVHEA AFFFEAAALG


 


201
KAHFAGETPL FHTGEEDGVE FQAFGGVDGH QLDGFFACPC LVFAGFEGGV


 


251
AQEGEDGEGG IV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1545>:










m535.seq




1
aTGCCCTTtC CCGTTTTCAG ACGGCCTTTT GCTTTGTCCT TACTtACGTT


 


51
TTTTGCCGTA AGTCAGATTC TTGTATCCGA CATTTCCAAC AGCGGTGTTT


 


101
CGGAAACAAT AGACGCGTCA AATGTTTTTG TCGGATACGA ATATCCGACC


 


151
TACATTTCAA ATTTACATCT CTTCCAATTT CGCAAACTTG GTGTCCAACT


 


201
CTTTCACGCC CTGTTTGCCG AAATTGATGG TCAGTCGGGC GGATTCGCCT


 


251
TTATCTGCGG CATCGATAAT CACGCCGGTG CCGAATTTGG CGTGGCGGAC


 


301
GTTTTGTCCG ATACGGAAAC CTGCGTAGGT TTGGGGCTGT TTGTAGTCGT


 


351
CGATGATTTT ATCTTTGGAT GCGGCGGTTT GGCGCGTGTT GCCGTAACTG


 


401
TCGTAGGCAG GCTTTTTGAC GGACAGGTAG TGCAATACTT CGGGTGGGAT


 


451
CTCTTCGACG AAGCGGGAGA CGATGCCGAA TTGGGTTTGT CCGTGCAGCA


 


501
TGCGTTGTTG CGCCATGGTG ATGTAGAGGC GTTTGCGGGC GCGGGTGATG


 


551
GCGACGTACA TGAGGCGGCG TTCTTCTTCG AGGCCGCCGC GTTCGGCAAG


 


601
GCTCATTTCG CTGGGGAAGC GGCCTTCTTC CATGCCGGTG AGGAAGACGG


 


651
CGTTAAATTC CAAGCCTTTG GCGGCGTGGA CGGTCATGAG TTGGACGGCC


 


701
TTTTCGCCTG CGCCTGCCTG GTTTTCACCG GATTCGAGGG CGGCATTGCT


 


751
TAGGAAGGCG AGAATGGGGA AGGCGGGGTC GTCTGA






This corresponds to the amino acid sequence <SEQ ID 1546; ORF 535>:










m535.pep




1
MPFPVFRRPF ALSLLTFFAV SQILVSDISN SGVSETIDAS NVFVGYEYPT


 


51
YISNLHLFQF RKLGVQLFHA LFAEIDGQSG GFAFICGIDN HAGAEFGVAD


 


101
VLSDTETCVG LGLFVVVDDF IFGCGGLARV AVTVVGRLFD GQVVQYFGWD


 


151
LFDEAGDDAE LGLSVQHALL RHGDVEAFAG AGDGDVHEAA FFFEAAAFGK


 


201
AHFAGEAAFF HAGEEDGVKF QAFGGVDGHE LDGLFACACL VFTGFEGGIA


 


251
XEGENGEGGV V*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 535 shows 80.9% identity over a 262 aa overlap with a predicted ORF (ORF 535.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1547>:









a535.seq (partial)










1
TTCAGACGGC CTTTTGCCTT GTCCTTGCTA CAGTTTTTTG CCATAGGTCG



 


51
GATTCTCGAA TCCGACATTT CCAACAGCGG TTTTTCGGAA ACGATAGACG


 


101
CGTCAAATAT TTTTGTCGGA TACGAGTATC CAGCCTGCAT TTCAAATTTA


 


151
CATCGCTTCC AATTTCGCAA ACTTGGTGTC CAACTCTTTC ACGCCCTGTT


 


201
TGCCGAAATT GATGGTCAGT CGGGCGGATT CGCCTTTATC TGCGGCATCG


 


251
ATAATCACGC CGGTGCCGAA TTTGGCGTGG CGGACGTTTT GTCCGATACG


 


301
GAAACCTGCG TAGGTTTGGG GCTGTTTGTA GTCGTCGATG ATTTTGTCTT


 


351
TGGGCGCGGC GGTTTGGCGC GTGTTGCCAT AGCGGTCGTA GGCGGGTTTT


 


401
TTGACGGACA GGTAGTGCAA TACTTCGGGC GGGATTTCTT CGACGAAGCG


 


451
GGAGACGATG CCGAATTGGG TTTGTCCGTG CAGCATGCGT TGTTGCGCCA


 


501
TGGTGATGTA GAGGCGTTTG CGGGCGCGGG TGATGGCGAC GTACATCAGG


 


551
CGGCGTTCTT CTTCGAGGCC GCCGCGTTCG GCAAGGCTCA TTTCGCTGGG


 


601
GAAGCGGCCT TCTTCCATGC CGGTGAGGAA TACGGCGTTA AATTCCAAGC


 


651
CTTTGGCGGC GTGCACGGTC ATGAGTTGTA CGGCTTTTTC GCCCGCGCCT


 


701
GCTTGGTTTT CGCCGGATTC GAGAGCAGCA TTGCTTAGGA AAGCGAGGAT


 


751
GGGGAAGGCG GGGTCGTCTG A






This corresponds to the amino acid sequence <SEQ ID 1548; ORF 535.a>:









a535.pep (partial)










1
FRRPFALSLL QFFAIGRILE SDISNSGFSE TIDASNIFVG YEYPACISNL



 


51
HRFQFRKLGV QLFHALFAEI DGQSGGFAFI CGIDNHAGAE FGVADVLSDT


 


101
ETCVGLGLFV VVDDFVFGRG GLARVAIAVV GGFFDGQVVQ YFGRDFFDEA


 


151
GDDAELGLSV QHALLRHGDV EAFAGAGDGD VHQAAFFFEA AAFGKAHFAG


 


201
EAAFFHAGEE YGVKFQAFGG VHGHELYGFF ARACLVFAGF ESSIA*ESED


 


251
GEGGVV*






m535/a535 88.7% identity in 256 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1549>:










g537.seq




1
atgaaatccc tttttatttg gctgcttcta ttgggctcgg cggcaggcgt


 


51
tttctaccat acccaaaacc aatccctgcc cgcgggcgaa cttgtctatc


 


101
cgtccgcacc gcaaatcagg gacggcggcg atgcgctgca ctacctcaac


 


151
cgcatccgca cacaaatcgg tttgcacgcg ctggcacacg cgccggtttt


 


201
ggaaaattcc gcccgcaggc acgcacgcta tctcacgctc aatcccgaag


 


251
acggacacgg cgaacaccat cccgacaatc cgcactacac cgcacaaaag


 


301
ctgaccgaac gcacacgcct tgccgggtat ctctacaacg gcgtgcatga


 


351
aaacatcagc acggaagagg aagccgccga atcgtccgac agcgacatcc


 


401
gcacgcagca acgccaagtg gacgctttga tgagcgcaat ctaccaccgc


 


451
ctttcgctgc ttgaccgcca taccgacgaa gcaggtgcgg catttgtgcg


 


501
cgaaaacggc aaaaccgtcc tcgtattcaa tcagggcaac ggcagcttcg


 


551
agcgcgcctg tgcaaaagga aggcggcagc cggaagcagg acggaaatat


 


601
taccgcaacg cttgccacaa cggtgcggcc gtttatgctg acgaagccat


 


651
gcccgtaacg gaattgcttt ataccgccta tccggttggc ggcggcgcgc


 


701
tgccttattt ttacggggaa cgtcccgacc ccgtgccgga atatgaaatc


 


751
acaggcaatc ctgccagcat tgatttttcc gaggcggcag gcaaaattgc


 


801
gatgaaaagt ttcaagctgt atcagggtaa aaacgaaatc cgccccgtca


 


851
gggttttaac cgccggcaac gaccctaacg gcaggctgac cgcgcaccaa


 


901
ttcgcccttt tcccgctcaa acctttggaa tacggcacgc tttatacggc


 


951
ggtattcgac tatgtccgca acggacggca cgcgcaggcg aaatggcagt


 


1001
ttagaacccg aaaacccgat tacccttatt ttgaggtaaa cggcggcgag


 


1051
acacttgcgg ttagaaaagg cgaaaaatat ttcatccact ggcgcggacg


 


1101
ctggtgtctg gaagcgtgta cccgttatac ctaccggcgg cagttcggca


 


1151
acagcctgtc catactccgg cacgaagcgg gcggcattgt cttcagcgtc


 


1201
agcggaatgg cgggaagccg catcaggctt actccggaag acagcccgga


 


1251
acgcggtgta accctttatt tgcaggattg a






This corresponds to the amino acid sequence <SEQ ID 1550; ORF 537.ng>:










g537.pep




1
MKSLFIWLLL LGSAAGVFYH TQNQSLPAGE LVYPSAPQIR DGGDALHYLN


 


51
RIRTQIGLHA LAHAPVLENS ARRHARYLTL NPEDGHGEHH PDNPHYTAQK


 


101
LTERTRLAGY LYNGVHENIS TEEEAAESSD SDIRTQQRQV DALMSAIYHR


 


151
LSLLDRHTDE AGAAFVRENG KTVLVFNQGN GSFERACAKG RRQPEAGRKY


 


201
YRNACHNGAA VYADEAMPVT ELLYTAYPVG GGALPYFYGE RPDPVPEYEI


 


251
TGNPASIDFS EAAGKIAMKS FKLYQGKNEI RPVRVLTAGN DPNGRLTAHQ


 


301
FALFPLKPLE YGTLYTAVFD YVRNGRHAQA KWQFRTRKPD YPYFEVNGGE


 


351
TLAVRKGEKY FIHWRGRWCL EACTRYTYRR QFGNSLSILR HEAGGIVFSV


 


401
SGMAGSRIRL TPEDSPERGV TLYLQD *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1551>:









m537.seq (partial)










1
ATGAAATCCC TTTTTATTCG GCTGCTCCTG TTGGGTTCGG CGGCAGGCGT



 


51
TTTCTACCAT ACCCAAAmCC AATCCCTGCC CGCGGGCGAA CTTGTCTATC


 


101
CGTCCGCACC GCAAATCAGG GACGGCGGCG ATGCGCTGCA CTACCTCAAC


 


151
CGCATCCGAG CCCAAATCGG TTTGCACAAG CTGGCACACG CGCCGGTTTT


 


201
GGAAAACTCC GCCCGCAgGC ACGCAAGCTA CCTCACGCTC AATCCCGAAG


 


251
ACGGACACGG CGAACACCAT CCCGACAATC CGCACTACAC CGCACAAAAG


 


301
CTGACCGAAC GCACACGCCT TGCCGGGTAT CTCTACAACG GCGTGCATGA


 


351
AAACATCAGC ACGGAAGAAG AAGCCGCCGA ATCGTCCGAC AGCGACATCC


 


401
GCACGCAGCA ACGCCAAGTG GACGGATTAA TGAGCGCAAT CTACCACCGC


 


451
CTTTCCCTAC TTGACCGCCA TACGGATGAG TCAGGAGCGG CATT...






This corresponds to the amino acid sequence <SEQ ID 1552; ORF 537>:









m537.pep (partial)










1
MKSLFIRLLL LGSAAGVFYH TQXQSLPAGE LVYPSAPQIR DGGDALHYLN



 


51
RIRAQIGLHK LAHAPVLENS ARRHASYLTL NPEDGHGEHH PDNPHYTAQK


 


101
LTERTRLAGY LYNGVHENIS TEEEAAESSD SDIRTQQRQV DGLMSAIYHR


 


151
LSLLDRHTDE SGAA...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 537 shows 95.7% identity over a 164 aa overlap with a predicted ORF (ORF 537.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1553>:










a537.seq




1
ATGAAATCCC TTTTTATTCG GCTGCTCCTG TTGGGTTCGG CGGCCGGCGT


 


51
TTTCTATCAT ACCCAAAACC AATCCCTGCC CGCGGGCGAA CTTGTCTATC


 


101
CGTCCGCACC GCAAATCAGG GACGGCGGCG ATGCGCTGCA CTACCTCAAC


 


151
CGCATCCGCG CCCAAATCGG TTTGCACAAG CTGGCACACG CGCCGGTTTT


 


201
GGAAAATTCC GCCCGCAGGC ACGCACGCTA TCTCACGCTC AATCCCGAAG


 


251
ACGGACACGG CGAACACCAT CCCGACAATC CGCACTACAC CGCACAAAAG


 


301
CTGACCGAAC GCACACGCCT TGCCGGGTAT CTCTACAACG GCGTGCATGA


 


351
AAACATCAGC ACGGAAGAGG AAGCCGCCGA ATCGTCCGAC AGCGACATCC


 


401
GCACGCAGCA ACGCCAAGTG GACGGATTAA TGAGCGCAAT CTACCACCGC


 


451
CTTTCCCTAC TTGACCGCCA TACGGATGAG GCAGGAGCGG CATTTGTGCG


 


501
CGAAAACGGT AAAACCGTTC TCGTATTCAA TCAGGGCAAC GGCAGGTTTG


 


551
AGCGGCATTG CGCCCAAGGC AGAAATCAGC CGGAAGCAGG ACGGAAATAT


 


601
TACCGCAACG CCTGCCATAA CGGTGCGGTC GTGTACACCG ACGAAGCCAT


 


651
GCCCGCACAG GAGCTGCTCT ATACAGCCTA TCCCGTCGGC AACGGCGCAC


 


701
TGCCTTATTT CCACGGCGAG CGTCCAGACC CCGTGCCGGA ATATGAAATC


 


751
ACGGGCAATC CTGCCAGCAT TGATTTTTCC GAGGCGGCAG GCAAAATTAC


 


801
GATGAAAAGT TTCAAGCTGT ATCAGGGTAA AAACGAAATC CGCCCCGTCA


 


851
GGGTTTTAAC CGCCGGCAAC GACCCCAACG GCAGGCTGAC CGCGTACCAA


 


901
TTCGCGCTTT TCCCGCTCAA GCCTTTGGAA TACGGTACGC TTTATACGGC


 


951
GGTATTCGAC TATGTCCGCA ACGGACGGCG CGCGCAGGCG AAATGGCAGT


 


1001
TTAGAACCCG AAAACCCGAT TACCCTTATT TTGAGGTAAA CGGCGGCGAG


 


1051
ACACTTGCGG TTAGAAAAGG CGAAAAATAT TTCATCCACT GGCGCGGACG


 


1101
CTGGTGTTTG GAAGCGTGTA CCCGTTATAC CTACCGGCAG CGACCCGGCA


 


1151
GCCGCCTGTC CATAGGAAGG CACAAGGCGG GCGGCATCGT CTTCAGCGTT


 


1201
GACGGAATGG CGGGCAGCCG CATCACGCTT GCACCGGAAG GAGAAACGGA


 


1251
ACGAGGCGTA ACCCTTTATT TACAGGATTG A






This corresponds to the amino acid sequence <SEQ ID 1554; ORF 537.a>:










a537.pep




1
MKSLFIRLLL LGSAAGVFYH TQNQSLPAGE LVYPSAPQIR DGGDALHYLN


 


51
RIRAQIGLHK LAHAPVLENS ARRHARYLTL NPEDGHGEHH PDNPHYTAQK


 


101
LTERTRLAGY LYNGVHENIS TEEEAAESSD SDIRTQQRQV DGLMSAIYHR


 


151
LSLLDRHTDE AGAAFVRENG KTVLVFNQGN GRFERHCAQG RNQPEAGRKY


 


201
YRNACHNGAV VYTDEAMPAQ ELLYTAYPVG NGALPYFHGE RPDPVPEYEI


 


251
TGNPASIDFS EAAGKITMKS FKLYQGKNEI RPVRVLTAGN DPNGRLTAYQ


 


301
FALFPLKPLE YGTLYTAVFD YVRNGRRAQA KWQFRTRKPD YPYFEVNGGE


 


351
TLAVRKGEKY FIHWRGRWCL EACTRYTYRQ RPGSRLSIGR HKAGGIVFSV


 


401
DGMAGSRITL APEGETERGV TLYLQD*






m537/a537 98.2% identity in 164 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1555>:










g538.seq




1
atgtcaggta gaacaggacg gaacagtgcc actcaggcgc aaccggaacg


 


51
cgtcatgctg gtgggcgtaa tgttggataa agatgatacg ggcagcaatg


 


101
ccgcccgtct gaacggtttt cagacggcat tggcggaagc cgtcgagctg


 


151
gtcaaagcgg cgggcggcga ttccgtacgc gtggagactg ccaaacgcga


 


201
ccgcccgcac actgcgctgt ttgtcggcac gggcaaggcg gcggagctgt


 


251
cggaagcagt tgccgcagac ggcattgatt tggtcgtatt caaccacgaa


 


301
cttactccca cgcaggaacg caatttggaa aaaatcctcc aatgccgcgt


 


351
attggacaga gtggggctga ttctggcgat tttcgcccgc cgcgcccgca


 


401
cgcaggaagg caggctgcaa gtcgagttgg cgcaattgag ccatttggcg


 


451
ggacgcttga tacgcggtta cggacatttg caaagccagc gcggcggtat


 


501
cggcatgaaa gggccgggcg aaaccaaact ggaaaccgac cgccgattaa


 


551
ccgcccatcg gatcaacgcc ttgaaaaaac agcttgccaa cctcaaaaaa


 


601
cagcgcgccc tgcgccgcaa gtcccgcgag tcgggcagaa tcaaaacgtt


 


651
tgcgctggtc ggctatacca atgtcggcaa atccagcctg ttcaaccggc


 


701
tgaccaagtc gggcatatat gcgaaagacc agcttttcgc cactctcgac


 


751
acgacggcgc ggcggctgta catcagtccc gcatgcagca ttatcctgac


 


801
cgataccgtc ggattcgtca gcgatctgcc gcacaaactg atttccgcct


 


851
tttccgccac cttggaagaa accgtgcaag ccgatgtgct gctgcacgtc


 


901
gtcgatgctg ccgcccggaa cagcgggcag cagattgaag acgtggaaaa


 


951
cgtactgcaa gaaatccatg cccacgatat tccgtgcatc aaggtgtaca


 


1001
acaaaaccga cctgctgccg tctgaagaac aaaacacggg catatggcgc


 


1051
gacgctgcgg gaaaaattgc cgccgtccgc atttccgttg ctgaaaatac






This corresponds to the amino acid sequence <SEQ ID 1556; ORF 538.ng>:










g538.pep




1
MSGRTGRNSA TQAQPERVML VGVMLDKDDT GSNAARLNGF QTALAEAVEL


 


51
VKAAGGDSVR VETAKRDRPH TALFVGTGKA AELSEAVAAD GIDLVVFNHE


 


101
LTPTQERNLE KILQCRVLDR VGLILAIFAR RARTQEGRLQ VELAQLSHLA


 


151
GRLIRGYGHL QSQRGGIGMK GPGETKLETD RRLTAHRINA LKKQLANLKK


 


201
QRALRRKSRE SGRIKTFALV GYTNVGKSSL FNRLTKSGIY AKDQLFATLD


 


251
TTARRLYISP ACSIILTDTV GFVSDLPHKL ISAFSATLEE TVQADVLLHV


 


301
VDAAARNSGQ QIEDVENVLQ EIHAHDIPCI KVYNKTDLLP SEEQNTGIWR


 


351
DAAGKIAAVR ISVAENTGID ALREAIAEYC AAAPNTDETE MP*






The following partial DNA sequence was identified in N. meningitis <SEQ ID 1557>:










m538.seq




1
ATGACAGGCA GAACAGGCGG CAACGGCAGT ACCCAAGCGC AACCCGAACG


 


51
CGTCATGCTG GTGGGCGTAA TGTTGGACAA AGATGGTACG GGCAGTAGTG


 


101
CCGCCCGTCT GAACGGTTTT CAGACGGCAT TGGCGGAAGC TGTCGAGCTG


 


151
GTCAAAGCGG CGGGCGGCGA TTCCGTGCGC GTGGAGACTG CCAAACGCGA


 


201
CCGTCCGCAC ACCGCGCTGT TTGTCGGCAC GGGCAAGGCG GCGGAGCTGT


 


251
CAGAAGCAGT TGCCGCAGAC GGCATCGATT TGGTCGTATT CAACCACGAA


 


301
CTCACGCCCA CGCAGGAACG CAACCTTGAA AAAGAACTsA AATGCCGCGT


 


351
ATTGGACAGG GTAGGGCTGA TTCTGGCGAT TTTCGCTCGC CGCGCCCGCA


 


401
CGCAGGAAGG CAGGCTGCAA GTCGAGTTGG CGCAATTGAG CCATTTGGCG


 


451
GGACGCTTGA TACGCGGTTA CGGCCATCTG CAGAGCCAGC GCGGCGGTAT


 


501
CGGCATGAAA GGCCCCGGCG AAACCAAACT GGAAACCGAC CGCCGATTGA


 


551
TCGCCCATCG GATCAATGCC TTGATAAAAC AGCTTGCCAA CCTCAAAAAA


 


601
CAGCGCGCCC TGCGCCGCAA GTCnCGCGAA TCGGGCACAA TCAAAACGTT


 


651
TGCGCTGGTC GGCTATACAA ATGTCGGAAA ATCCAGCCTG TTCAACCGGC


 


701
TGACAAAGTC GGGCATATAT GCAAAGGACA AGCTTAGTCC CGAATGCAGC


 


751
ATTATCCTGA CCGATACCGT CGGATTCGTn AGCGATCTGC CGCAcAAACT


 


801
GATTTCCGCC TTTTCgCC.A CGCTGGAAGA AACCGCGCAA GCCGATGTGC


 


851
TGCTGCACGT CGTCGATGCC GCCGCTCCGA ACAGCGGACA GCAGATTGAA


 


901
GACGTGGAAA ACGTACTGCA AGAAATCCAT GCCGGCGATA TTCCGTGCAT


 


951
cAAGGTGTAC AACAAAACCG ACCTGCTGCC GTCTGAAGAA CAAAACACGG


 


1001
GCATATGGCG CGACGCTGCG GGAAAAATTG CCGCCGTCCG CATTTCCGTT


 


1051
GCTGAAAATA CCGGTATAGA CGCACTGCGC GAAGCcATTG CCGAGTCTTG


 


1101
TGCCGCCGCA CCAAACACAG ACGAAACCGA AATGCCATGA






This corresponds to the amino acid sequence <SEQ ID 1558; ORF 538>:










m538.pep




1
MTGRTGGNGS TQAQPERVML VGVMLDKDGT GSSAARLNGF QTALAEAVEL


 


51
VKAAGGDSVR VETAKRDRPH TALFVGTGKA AELSEAVAAD GIDLVVFNHE


 


101
LTPTQERNLE KELKCRVLDR VGLILAIFAR RARTQEGRLQ VELAQLSHLA


 


151
GRLIRGYGHL QSQRGGIGMK GPGETKLETD RRLIAHRINA LIKQLANLKK


 


201
QRALRRKSRE SGTIKTFALV GYTNVGKSSL FNRLTKSGIY AKDKLSPECS


 


251
IILTDTVGFV SDLPHKLISA FSXTLEETAQ ADVLLHVVDA AAPNSGQQIE


 


301
DVENVLQEIH AGDIPCIKVY NKTDLLPSEE QNTGIWRDAA GKIAAVRISV


 


351
AENTGIDALR EAIAESCAAA PNTDETEMP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 538 shows 92.1% identity over a 392 aa overlap with a predicted ORF (ORF 538.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1559>:










a538.seq




1
ATGACAGGCA GAACAGGCCG CAACGGCAGT ACCCAAGCGC AACCCGAACG


 


51
CGTCATGCTG GTGGGCGTAA TGTTGGACAA AGATGGTACG GGCAGCAGTG


 


101
CCACCCGTCT GAACGGTTTT CAGACGGCAT TGGCGGAAGC TGTCGAGCTG


 


151
GTCAAAGCGG CGGGCGGCGA TTCCGTGCGC GTGGAGACTG CCAAACGCGA


 


201
CCGTCCGCAC ACCGCGCTGT TTGTCGGCAC GGGCAAGGCG GCGGAGCTGT


 


251
CGGAAGCAGT TGCCGCAGAC GGCATCGATT TGGTCGTATT CAACCACGAA


 


301
CTTACGCCCA CGCAGGAACG CAATTTGGAA AAAATCCTCC AATGCCGCGT


 


351
ATTGGACAGA GTGGGGCTGA TTCTGGCGAT TTTCGCCCGC CGCGCCCGCA


 


401
CGCAGGAAGG CAGGCTGCAA GTCGAGTTGG CACAATTGAG CCATTTGGCG


 


451
GGACGCTTGA TACGCGGTTA CGGCCATCTG CAGAGCCAGC GCGGCGGTAT


 


501
CGGCATGAAA GGCCCCGGCG AAACCAAACT GGAAACCGAC CGCCGATTGA


 


551
TCGCCCATCG GATCAATGCC TTGAAAAAAC AGCTTGCCAA CCTCAAAAAA


 


601
CAGCGCGCCC TGCGCCGCAA GTCCCGCGAA TCGGGCACAA TCAAAACGTT


 


651
TGCGCTGGTC GGCTATACCA ATGTCGGCAA ATCCAGTCTG TTCAACCGGC


 


701
TGACCAAGTC GGGCATATAT GCGAAAGACC AGCTTTTCGC CACACTCGAC


 


751
ACGACGGCGC GGCGGCTGTA CATCAGTCCC GAATGCAGCA TTATCCTGAC


 


801
CGATACCGTC GGATTCGTCA GCGATCTGCC GCACAAACTG ATTTCCGCCT


 


851
TTTCCGCCAC GCTGGAAGAA ACCGCGCAAG CCGATGTGCT GCTGCACGTC


 


901
GTCGATGCCG CCGCTCCGAA CAGCGGACAG CAGATTGAAG ACGTGGAAAA


 


951
CGTACTGCAA GAAATCCATG CCGGCGATAT TCCGTGCATC AAGGTGTACA


 


1001
ACAAAACCGA CCTGCTGCCG TCTGAAGAAC AAAACACGGG CATATGGCGC


 


1051
GACGCTGCGG GAAAAATTGC CGCCGTCCGC ATTTCCGTTG CTGAAAATAC


 


1101
CGGTATAGAC GCACTGCGCG AAGCCATTGC CGAGTATTGT GCCGCCGCAC


 


1151
CAAACACAGA CGAAACCGAA ATGCCATGA






This corresponds to the amino acid sequence <SEQ ID 1560; ORF 538.a>:










a538.pep




1
MTGRTGRNGS TQAQPERVML VGVMLDKDGT GSSATRLNGF QTALAEAVEL


 


51
VKAAGGDSVR VETAKRDRPH TALFVGTGKA AELSEAVAAD GIDLVVFNHE


 


101
LTPTQERNLE KILQCRVLDR VGLILAIFAR RARTQEGRLQ VELAQLSHLA


 


151
GRLIRGYGHL QSQRGGIGMK GPGETKLETD RRLIAHRINA LKKQLANLKK


 


201
QRALRRKSRE SGTIKTFALV GYTNVGKSSL FNRLTKSGIY AKDQLFATLD


 


251
TTARRLYISP ECSIILTDTV GFVSDLPHKL ISAFSATLEE TAQADVLLHV


 


301
VDAAAPNSGQ QIEDVENVLQ EIHAGDIPCI KVYNKTDLLP SEEQNTGIWR


 


351
DAAGKIAAVR ISVAENTGID ALREAIAEYC AAAPNTDETE MP*






m538/a538 94.6% identity in 392 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1561>:










g539.seq




1
atggaggatc tgcaggaaat cgggttcgat gtcgccgccg taaaggtagg


 


51
tcggcagcgc gaacatcatc gtctgcatca tacccagtcc ggcaacggca


 


101
aggcggacga tgtattgttt gcgttctttt tggttggcgg cttcgatttt


 


151
ttgcgcgtca tagggtgcgg cggtgtagcc tgtctgccgg attttcaaca


 


201
gaatgtcgga gaggcggatt ttgccgtcgt cccagacgac gcggcagcgg


 


251
tgcgtgctgt aattgaggtc gatgcggacg atgccgtctg tgcgcaaaag


 


301
ctgctgttcg atcagccaga cgcaggcggc gcaggtaatg ccgctgagca


 


351
tcagcactgc ttcgtgcgtg ccattatggg tttccacaaa gtcggattgg


 


401
acttcgggca ggtcgtacag gcggatttgg tcgaggattt cttggggcgg


 


451
cagttcggtt tttttcgcgt cggcggtgcg tcgtttgtaa taactgccca


 


501
agccggaatc gatgatgctt tgtgcgactg cctgacagcc gacgcagcag


 


551
gtttcgcggt cttcgccttc gtagcggacg gtcagatgca ggttttcggg


 


601
aacgtccagc ccgcagtgga aacaggtttt tttcatggca tttcggtttc


 


651
gtctgtgttt ggtgcggcgg cacaatactc ggcaatggct tcgcgcagtg


 


701
cgtctatacc ggtattttca gcaacggaaa tgcggacggc ggcaattttt


 


751
cccgcagcgt cgcgccatat gcccgtgttt tgttcttcag acggcagcag


 


801
gtcggttttg ttgtacacct tgatgcacgg aatatcgtgg gcatggattt


 


851
cttgcagtac gttttccacg tcttcaatct gctgcccgct gttccgggcg


 


901
gcagcatcga cgacgtgcag cagcacatcg gcttgcacgg tttcttccaa


 


951
ggtggcggaa aaggcggaaa tcagtttgtg cggcagatcg ctgacgaatc


 


1001
cgacggtatc ggtcaggata atgctgcatg cgggactgat gtacagccgc


 


1051
cgcgccgtcg tgtcgagagt ggcgaaaagc tggtctttcg catatatgcc


 


1101
cgacttggtc agccggttga acaggctgga tttgccgaca ttggtatag






This corresponds to the amino acid sequence <SEQ ID 1562; ORF 539.ng>:










g539.pep




1
MEDLQEIGFD VAAVKVGRQR EHHRLHHTQS GNGKADDVLF AFFLVGGFDF


 


51
LRVIGCGGVA CLPDFQQNVG EADFAVVPDD AAAVRAVIEV DADDAVCAQK


 


101
LLFDQPDAGG AGNAAEHQHC FVRAIMGFHK VGLDFGQVVQ ADLVEDFLGR


 


151
QFGFFRVGGA SFVITAQAGI DDALCDCLTA DAAGFAVFAF VADGQMQVFG


 


201
NVQPAVETGF FHGISVSSVF GAAAQYSAMA SRSASIPVFS ATEMRTAAIF


 


251
PAASRHMPVF CSSDGSRSVL LYTLMHGISW AWISCSTFST SSICCPLFRA


 


301
AASTTCSSTS ACTVSSKVAE KAEISLCGRS LTNPTVSVRI MLHAGLMYSR


 


351
RAVVSRVAKS WSFAYMPDLV SRLNRLDLPT LV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1563>:









m539.seq (partial)










1
ATGGAGGATT TGCAGGAAAT CGGGTTCGAT GTCGCCGCCG TAAAGGTAGG



 


51
TCGGCAGCGC GAACATCATC GTCTGCATCA TCCCCAGCCC GGCAACGGCG


 


101
AGGCGGACGA TGTATTGTTT GCGTTCTTTT TGGTTGGCGG CTTCGATTTT


 


151
TTGCGCGTCA TAGGGTGCGG CGGTGTAGCC TATCTGCCTG ATTTTCAACA


 


201
GAATGTCGGA AAGGCGGATT TTGCCGTCGT CCCAGACGAc GCGGCaGCgG


 


251
TGCGTGCTGT AATTGAGGTC GATGCGGACG ATGCCGTCTG TACGCAAAAG


 


301
CTGCTGTTCG ATCAGCCAGA CGCAGGCGGC GCAGGTGATG CCGCCGAGCA


 


351
TTAAAACCGC CTCGCGCGTG CCGCCGTGGG TTTCCACAAA GTCGGACTGG


 


401
ACTTCGGGCA GGTCGTACAG GCGGATTTGG TCGAGGATTT CTTGGGGCGG


 


451
CAgCTCGGTT TTTTGCGCGT CGGCGGTGCG TTGTTTGTAA TAACTGCCCA


 


501
AGCCCGCGTC AATAATGCTT TGTGCGACCG CCTGACAGCC GGCGCaCAgG


 


551
GTTTCGCGGT CTTCGTTTTC GTAACGGACA GTCAGGTGGA GGTGTTCGGG


 


601
AACATCCAGA CCGCAGTGGA AACAGGTTTT TTTCATGGCA TTTCGGTTTC


 


651
GTCTGTGTTT GGTGCGGCGG CACAAGACTC GGCAATgGCT TCGCGCAGTG


 


701
CGTCTATACC GGTATTTTCA GCAACGGAAA TGCGGACGGC GGCAATTTTT


 


751
CCCGCAGCGT CGCGCCATAT GTCTGTGTTT TGTTCTTCAG ACGGCAGCAG


 


801
GTCGGTTTTG TTGTACACCT TgATGCACGG AATATCGCCG GCATGGATTT


 


851
CTTGCAGTAC GTTTTCCACG TCTTCAATCT GCTGTCCGCT GTTCGGAGCG


 


901
GCGGCATCGA CGACGTGCAG CAGCACATCG GCTTGCGCGG TTTCTTCCAG


 


951
CGTGGcG.AA AAGGCGGAAA TCAGTTTgTG CGGCAGATCG CTnACGAATC


 


1001
CGACGGTATC GGTCAGGATA ATGCTGCATT CGGGAC...






This corresponds to the amino acid sequence <SEQ ID 1564; ORF 539>:









m539.pep (partial)










1
MEDLQEIGFD VAAVKVGRQR EHHRLHHPQP GNGEADDVLF AFFLVGGFDF



 


51
LRVIGCGGVA YLPDFQQNVG KADFAVVPDD AAAVRAVIEV DADDAVCTQK


 


101
LLFDQPDAGG AGDAAEH*NR LARAAVGFHK VGLDFGQVVQ ADLVEDFLGR


 


151
QLGFLRVGGA LFVITAQARV NNALCDRLTA GAQGFAVFVF VTDSQVEVFG


 


201
NIQTAVETGF FHGISVSSVF GAAAQDSAMA SRSASIPVFS ATEMRTAAIF


 


251
PAASRHMPVF CSSDGSRSVL LYTLMHGISP AWISCSTFST SSICCPLFGA


 


301
AASTTCSSTS ACAVSSSVAX KAEISLCGRS LTNPTVSVRI MLHSG....






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 539 shows 89% identity over a 345 aa overlap with a predicted ORF (ORF 539.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1565>:










a539.seq




1
ATGGAGGATT TGCAGGAAAT CGGGTTCGAT GTCGCCGCCG TAAAGGTAGG


 


51
TCGGCAGCGC GAACATCATC GTCTGCATCA TCCCCAGCCC GGCAACGGCG


 


101
AGGCGGACGA TGTATTGTTT GCGTTCTTTT TGGTTGGCGG CTTCGATTTT


 


151
TTGCGCGTCA TAGGGTGCGG CGGTGTAGCC TATCTGCCTG ATTTTCAACA


 


201
GAATGTCGGA AAGGCGGATT TTGCCGTCGT CCCAGACGAC GCGGCAGCGG


 


251
TGCGTGCTGT AATTGAGGTC GATGCGGACG ATGCCGTCTG TACGCAAAAG


 


301
CTGCTGTTCG ATCAGCCAGA CGCAGGCGGC GCAGGTGATG CCGCCGAGCA


 


351
TTAAAACCGC CTCGCGCGTG CCGCCGTGGG TTTCCACAAA GTCGGACTGG


 


401
ACTTCGGGCA GGTCGTACAG GCGGATTTGG TCGAGGATTT CTTGGGGCGG


 


451
CAGCTCGGTT TTTTGCGCGT CGGCGGTGCG TTGTTTGTAA TAACTGCCCA


 


501
AGCCCGCGTC AATAATGCTT TGTGCGACTG CCTGACAACC GGCGCAGCAG


 


551
GTTTCGCGGT CTTCGTTTTC GTAACGGACG GTCAGATGCA GGTTTTCGGG


 


601
AACGTCCAGC CCGCAGTGGA AACAGGTTTT TTTCATGGCA TTTCGGTTTC


 


651
GTCTGTGTTT GGTGCGGCGG CACAATACTC GGCAATGGCT TCGCGCAGTG


 


701
CGTCTATACC GGTATTTTCA GCAACGGAAA TGCGGACGGC GGCAATTTTT


 


751
CCCGCAGCGT CGCGCCATAT GCCCGTGTTT TGTTCTTCAG ACGGCAGCAG


 


801
GTCGGTTTTG TTGTACACCT TGATGCACGG AATATCGCCG GCATGGATTT


 


851
CTTGCAGTAC GTTTTCCACG TCTTCAATCT GCTGTCCGCT GTTCGGAGCG


 


901
GCGGCATCGA CGACGTGCAG CAGCACATCG GCTTGCGCGG TTTCTTCCAG


 


951
CGTGGCGGAA AAGGCGGAAA TCAGTTTGTG CGGCAGATCG CTGACGAATC


 


1001
CGACGGTATC GGTCAGGATA ATGCTGCATT CGGGACTGAT GTACAGCCGC


 


1051
CGCGCCGTCG TGTCGAGTGT GGCGAAAAGC TGGTCTTTCG CATATATGCC


 


1101
CGACTTGGTC AGCCGGTTGA ACAGACTGGA TTTGCCGACA TTGGTATAG






This corresponds to the amino acid sequence <SEQ ID 1566; ORF 539.a>:










a539.pep




1
MEDLQEIGFD VAAVKVGRQR EHHRLHHPQP GNGEADDVLF AFFLVGGFDF


 


51
LRVIGCGGVA YLPDFQQNVG KADFAVVPDD AAAVRAVIEV DADDAVCTQK


 


101
LLFDQPDAGG AGDAAEH*NR LARAAVGFHK VGLDFGQVVQ ADLVEDFLGR


 


151
QLGFLRVGGA LFVITAQARV NNALCDCLTT GAAGFAVFVF VTDGQMQVFG


 


201
NVQPAVETGF FHGISVSSVF GAAAQYSAMA SRSASIPVFS ATEMRTAAIF


 


251
PAASRHMPVF CSSDGSRSVL LYTLMHGISP AWISCSTFST SSICCPLFGA


 


301
AASTTCSSTS ACAVSSSVAE KAEISLCGRS LTNPTVSVRI MLHSGLMYSR


 


351
RAVVSSVAKS WSFAYMPDLV SRLNRLDLPT LV*






m539/a539 97.1% identity in 345 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1567>:










g540.seq




1
atgccgccct cccgacgcgg caacggggtg ttttatcaaa acggcaaact


 


51
tgccaatgcg gtttccgctt gccgattgcc aaaccggcaa acctttcccg


 


101
tgccggtgcc gaacccgatg ccgtctgaac cttcagacgg catcgggtgt


 


151
ttatttgtcc actcggacgg gtgcaggttc gtattgtgtc gattcgtcgc


 


201
cgtaatacag cacgccgagt ttgacgggga tgcgtccctg cgatttgcgg


 


251
tgggcgttgg aatcgcgcaa ggaatacgcg cagccgcagt attcctgctg


 


301
gtagaagttt tcgcgtttgc tgatttcaat catacgcgcg ccgccgccgc


 


351
ctttgcgcca gttgaagtcc caataggcca catcatcgta aggcgcggcg


 


401
gcacggtgtc cgcagtcgtt gatttgcgcc atatttttcc agcgtga






This corresponds to the amino acid sequence <SEQ ID 1568; ORF 540.ng>:










g540.pep




1
MPPSRRGNGV FYQNGKLANA VSACRLPNRQ TFPVPVPNPM PSEPSDGIGC


 


51
LFVHSDGCRF VLCRFVAVIQ HAEFDGDASL RFAVGVGIAQ GIRAAAVFLL


 


101
VEVFAFADFN HTRAAAAFAP VEVPIGHIIV RRGGTVSAVV DLRHIFPA *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1569>:









m540.seq (partial)










1
..CCGAACCCGA TGCCGTCTGA ACCTTCAGAC GGCATCGGGT GTTTATTTGT



 


51
  CCACCCGGAT GGGGGCAGGT TCGTATTGTG TCGATTCGTC GCCGTAATAC


 


101
  AGCACGCCGA GTTTGATGGG GATTCTGCCC TGTGATTTGC GGTGGGCATT


 


151
  GGAATCCCTC AGGGAATAGG CACAACCGCA ATATTCCTGC TGGTAGAAGT


 


201
  TTTCACGTTT GCTGATTTCA ATCATGCGCG CGCTGCCGCC GCCTTTGCGC


 


251
  CAGTTGAAAT CCCAATACAC CACATCATCG TAAGGCGCGG CGGCGCGGTG


 


301
  TCCGCAGTCG TTGATTTGCG CCATATTTTT CCAGCGTGA






This corresponds to the amino acid sequence <SEQ ID 1570; ORF 540>:









m540.pep (partial)










1
..PNPMPSEPSD GIGCLFVHPD GGRFVLCRFV AVIQHAEFDG DSAL*FAVGI



 


51
  GIPQGIGTTA IFLLVEVFTF ADFNHARAAA AFAPVEIPIH HIIVRRGGAV


 


101
  SAVVDLRHIF PA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 540 shows 85.7% identity over a 112 aa overlap with a predicted ORF (ORF 540.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1571>:










a540.seq




1
ATGCCGTCCT CCCGACGCGG CAACGGGGTG TTTTATCAAA ACGGCAAACT


 


51
TGCCAATGCG GTTTCCGATT GCAGATTGCC AAACCGGCAA ACCTTTCCCG


 


101
TGCCGATGCC GAACCCGATG CCGTCTGAAC CTTCAGACGG CATCGGGTGT


 


151
TTATTTGTCC ACCCGGATGG GTGCAGGTTC GTATTGTGTC GATTCGTCGC


 


201
CGTAATACAG CACGCCGAGT TTGATGGGGA TTCTGCCCTG TGATTTGCGG


 


251
TGGGCGTTGG AATCCCTCAG GGAATAGGCA CAACCGCAAT ATTCCTGCTG


 


301
GTAGAAGTTT TCACGTTTGC TGATTTCAAT CATACGCGCG CTGCCGCCGC


 


351
CTTTGCGCCA GTTGAAATCC CAATACACCA CATCATCGTA AGGCGCGGCG


 


401
GCGCGGCGGC CGCAGTCGTT AATCTGGTTC ATGTTTTTCC A






This corresponds to the amino acid sequence <SEQ ID 1572; ORF 540.a>:









a540.pep (partial)










1
MPSSRRGNGV FYQNGKLANA VSDCRLPNRQ TFPVPMPNPM PSEPSDGIGC



 


51
LFVHPDGCRF VLCRFVAVIQ HAEFDGDSAL *FAVGVGIPQ GIGTTAIFLL


 


101
VEFTFADFN HTRAAAAFAP VEIPIHHIIV RRGGAAAAVV NLVHVFP






m540/a540 92.8% identity in 111 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1573>:










g542.seq




1
atgccgaaat ggtcgcgcat acggcgttgc agcgtccttt cgctgatgtt


 


51
cagcgcggct gtcagccggt tgacttggtg tgcgccgccg tcgaacgcgg


 


101
cattcagggt gcggctgaag tcttcagacg gcatagcgtc tgcttccgcc


 


151
gtttgccccg ccgccggctc gatgccgtct gaaaccgtgt cccacaaatc


 


201
cgacagcagc cgcaacacgt ccgcctcgcg gcgcaatgtt tcgcccaaat


 


251
gcccctttgg gacggtttgc aggcaggatg ccgccaagcc gcgcaggttt


 


301
gggggcaaat cccatatcct gaccggttcg cggtaa






This corresponds to the amino acid sequence <SEQ ID 1574; ORF 542.ng>:










g542.pep




1
MPKWSRIRRC SVLSLMFSAA VSRLTWCAPP SNAAFRVRLK SSDGIASASA


 


51
VCPAAGSMPS ETVSHKSDSS RNTSASRRNV SPKCPFGTVC RQDAAKPRRF


 


101
GGKSHILTGS R*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1575>:










m542.seq




1
ATGCCGAAAT GGTCGCGCAT ACGGCGTTGC AGCGTCCTTT CACTGATGTT


 


51
CAGCGCGTCT GTCAGCCGGT TGACTTGGTG TGCGCCGTCG GCAAACGCGG


 


101
CATTTAGGGT GCGGCTGAAG TCTTCAGACG GCATAGCGTC TGCTTCCGCC


 


151
GTTTGCCCCG CCGCCGGCCC GATGCCGTCT GAAACCGTGT CCCACAAGTC


 


201
CGACAGCAGC CGCAACACGT CCGCCTCGCG .CGCAATGTT TCGCCCAAAT


 


251
GCCCCTTTGG GACGGCTTTC AGGCAGGATG CCGCCAAGCC GCGCAGGTTC


 


301
GGGGGCAAAT CCCATATCCT GACCGGTTCG CGGTAA






This corresponds to the amino acid sequence <SEQ ID 1576; ORF 542>:










m542.pep




1
MPKWSRIRRC SVLSLMFSAS VSRLTWCAPS ANAAFRVRLK SSDGIASASA


 


51
VCPAAGPMPS ETVSHKSDSS RNTSASRAMF RPNAPLGRNV SPKCPFGTAF


 


101
RQDAAKPRRF GGKSHILTGS R*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 542 shows 93.7% identity over a 111 aa overlap with a predicted ORF (ORF 542.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1577>:










a542.seq




1
ATGCCGAAAT GGTCGCGCAT ACGGCGTTGC AGCGTCCTTT CGCTGATGTT


 


51
CAGCGTGTCT GCCAGCCGGT TGACTTGATG TGCGCCGCCG GCAAACGCGG


 


101
CATTCAGGAT GCGGCTGAAG TCTTCAGACG GCATAGCGTC TGCTTCCGCC


 


151
GTTTGCCCCG CCGCCGGCCC GATGCCGTCT GAAACCGTGT CCCACAAGTC


 


201
CGACAGCAGC CGCAACACGT CCGCCTCGCG GCGCAATGTT TCGCCCAAAT


 


251
GCCCCTTTGG GACGGCTTTC AGGCAGGATG CCGCCAAGCC GCGCAGGTTC


 


301
GGGGGCAAAT CCCATATCCT GACCGGTTCG CGGTAA






This corresponds to the amino acid sequence <SEQ ID 1578; ORF 542.a>:










a542.pep




1
MPKWSRIRRC SVLSLMFSVS ASRLT*CAPP ANAAFRMRLK SSDGIASASA


 


51
VCPAAGPMPS ETVSHKSDSS RNTSASRRNV SPKCPFGTAF RQDAAKPRRF


 


101
GGKSHILTGS R*






m542/a542 94.6% identity in 111 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1579>:










g543.seq




1
atggtttgtc ggttatttgc cgccgttttt ggctttcaac tcggcaatca


 


51
gcccgtcgat gcctttggct ttgatgattt cgccgaattg gttgcggtac


 


101
acggtaacca ggctcgtgcc ttcgatggcg acgttgtagg tacggtattt


 


151
gccgccgctt tggtaggtgg taaagtccat attgacgggc ttctgaccgg


 


201
ggatgccgac ttcggcacgg acgacgattt ccttgccgcc cttattgacg


 


251
atgggattgt ctttgacgtt gacggtcgcg tttttgaatt tcagcatcgt


 


301
gccggaatag gtgcggatca gcagggtttg aaattctttg gccaacgctt


 


351
gtttttgcgc gtcggacgcg gtacgccaag ggttgccgac cgccaatgcg


 


401
gtcatacgtt ggaaatcgaa atagggaacc gcataggctt cggcttttgg


 


451
gcgtgcagaa gccgcgtcgc cgcttttgag gatggtcaaa acctgtgtgg


 


501
cgttttggcg gatttgtccc actgcgtcgg ccggggaggc aaatgccatg


 


551
ccgatgctca aaataccgat gcccaatgcg ctgatgaagg aggatttttt


 


601
cacgatgtct ttcctgaaaa tggatgtgta tgtttattct gcggcttttt


 


651
ccgcattgcc gccctcagcg tttttctcgg cgaagctggt catgaattta


 


701
ccgatcaggt tttccagaac cattgcagaa ctggttacgg agatggtgtc


 


751
gccggcagca aggttttccg tatcgccgcc ctgctgcagc ccgatgtact


 


801
gttcgcccaa aagtcccgaa gtcaggattt gcgcggaaac gtcactgctg


 


851
aactgatact tgccgtccaa atcaaggcgc accctcgcct gataggattt


 


901
cgggtcaagc ccgatagcgc cgacgcgccc gaccaatacg cctgcggatt


 


951
tgacgggggc attgaccttc aaaccgccga tgtcgccgaa atcggcataa


 


1001
acggcgtaag ttttgtccga accgccgaac gccgcgccgc ccgccacgcg


 


1051
gaaagcgaga aaggcaaccg ccgccgcgcc gatcaagacg aacagtccga


 


1101
cccaaaattc caatatgttc tttttcatta a






This corresponds to the amino acid sequence <SEQ ID 1580; ORF 543.ng>:










g543.pep




1
MVCRLFAAVF GFQLGNQPVD AFGFDDFAEL VAVHGNQARA FDGDVVGTVF


 


51
AAALVGGKVH IDGLLTGDAD FGTDDDFLAA LIDDGIVFDV DGRVFEFQHR


 


101
AGIGADQQGL KFFGQRLFLR VGRGTPRVAD RQCGHTLEIE IGNRIGFGFW


 


151
ACRSRVAAFE DGQNLCGVLA DLSHCVGRGG KCHADAQNTD AQCADEGGFF


 


201
HDVFPENGCV CLFCGFFRIA ALSVFLGEAG HEFTDQVFQN HCRTGYGDGV


 


251
AGSKVFRIAA LLQPDVLFAQ KSRSQDLRGN VTAELILAVQ IKAHPRLIGF


 


301
RVKPDSADAP DQYACGFDGG IDLQTADVAE IGINGVSFVR TAERRAARHA


 


351
ESEKGNRRRA DQDEQSDPKF QYVLFH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1581>:










m543.seq




1
ATGGTTTGTC GGTTATTTGC CGCCGTTTTT GGCTTTCAAC TCGGCAATCA


 


51
GTCCGTCCAC GCCTTTCGCT TTGATAATTT CGCCGAATTG GTTGCGGTAC


 


101
ACGGTAACCA GGCTCGCGCC TTCGATGGCG ACGTTGTAGG TACGGTATTT


 


151
ACCGCCGCTT TGGTAGGTGG TGAAGTCCAT GTTGACGGGT TTTTGCCCGG


 


201
GTACGCCGAC TTCGGCGCGG ACGATGATTT CTTTGCCGCC TTTATTGACG


 


251
ATGGGATTGT CTTTGACGTT GACGTTGGCG TTTTTTAATT TCAGCATCGT


 


301
GCCGGAATAG GTGCGGATCA GCAGGGTTTG AAATTCTTTG GCCAACGCTT


 


351
GTTTTTGCGC GTCGGACGCG GTGCGCCAAG GGTTGCCGAC CGCCAATGCG


 


401
GTCATACGTT GGAAATCGAA ATAGGGAATC GCATAGGCTT CGGCTTTTTG


 


451
GCGAGCGGTG TTGGCATCGC CGTTTTTTAA GATGCTCAAT ACTTGAGTGG


 


501
CGTTTTGACG GATTTGGCTT ACCGCGTCGG CAGGGGCGGC AAATGCCATG


 


551
CCGATGCTCA AAATACCGAT GCCCAATGCG CTGATGAGGG AGGATTTTTT


 


601
CATGATTAAG TGTCCTAGTT TGAATATGAT GGCATACGTT TATTCGGCGG


 


651
CTTTTTCCGC ATTGCCGCCG TCGGCATTTT TCTCGGCAAA ACTCGTCATG


 


701
AATTTGCCGA TAAGGTTTTC CAGAACCATT GCAGAACTGG TTACGGAGAT


 


751
GGTGTCGCCG GCAGCAAGGT TTTCCGTGTC GCCGCCCTGC TGCAGCCCGA


 


801
TGTACTGCTC GCCCAAAAGT CCCGAAGTCA GGATTTGCGC GGAAACGTCG


 


851
CTGCTGAACT GATACTTGCC GTCCAAATCG AGGCGCACCC TCGCCTGATA


 


901
GGATTTCGGG TCAAGTCCGA TAGCGCCGAC GCGCCCGACC AATACGCCTG


 


951
CGGATTTGAC GGGGGCATTG ACCTTCAAAC CGCCGATGTC GCCGAAATCG


 


1001
GCATAAACGG CGTAAGTTTT GTCCGAACCG CCGAACGCCG CACCGCCGGC


 


1051
CACGCGGAAA GCGAGAAAGG CAACCGCCGC CGCGCCAATC AGGACGAACA


 


1101
GTCCGACCCA AAATTCCAAT ATGTTCTTCT TCATTAA






This corresponds to the amino acid sequence <SEQ ID 1582; ORF 543>:










m543.pep




1
MVCRLFAAVF GFQLGNQSVH AFRFDNFAEL VAVHGNQARA FDGDVVGTVF


 


51
TAALVGGEVH VDGFLPGYAD FGADDDFFAA FIDDGIVFDV DVGVFXFQHR


 


101
AGIGADQQGL KFFGQRLFLR VGRGAPRVAD RQCGHTLEIE IGNRIGFGFL


 


151
ASGVGIAVFX DAQYLSGVLT DLAYRVGRGG KCHADAQNTD AQCADEGGFF


 


201
HDXVSXFEYD GIRLFGGFFR IAAVGIFLGK TRHEFADKVF QNHCRTGYGD


 


251
GVAGSKVFRV AALLQPDVLL AQKSRSQDLR GNVAAELILA VQIEAHPRLI


 


301
GFRVKSDSAD APDQYACGFD GGIDLQTADV AEIGINGVSF VRTAERRTAG


 


351
HAESEKGNRR RANQDEQSDP KFQYVLLH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 543 shows 84.2% identity over a 379 aa overlap with a predicted ORF (ORF 543.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1583>:










a543.seq




1
ATGGCTTATG GATTACTTGC TGCCGTTTNT AGCCTTCAAC TCGNCAATCA


 


51
GTCCGTCCAC GCCTTTCGCT TTGATAATTT CGCCGAATTG GTTGCGGTAC


 


101
ACGGTAACCA GGCTCGCGCC TTCGATGGCG ACGTTGTAGG TACGGTATTT


 


151
ACCGCCGCTT TGGTAGGTGG TGAAGTCCAT GTTGACGGGT TTTTGCCCGG


 


201
NNACGCCGAC TTCGGCGCGG ACGATGATTT CTTTGCCGCC TTTATTGACG


 


251
ATNGGATTGT CTTTGACGTT GACGTTGGCG TTTTTTAATT TCAGCATCGT


 


301
GCCGGAATAG GTGCGGATCA GCAGGGTTTG AAATTCTTTG GCCAACGCTT


 


351
GTTTTTGCGC GTCGGACGCG GTGCGCCAAG GGTTGCCGAC CGCCAATGCG


 


401
GTCATACGTT GGAAATCGAA ATAGGGAATC GCATAGGCTT CGGCTTTTTG


 


451
GCGGGCGGTG TTGGCATCAC CGCTTTTTAA GATGCTCAAT ACTTGAGTGG


 


501
CGTTTTGACG GATTTGGTTT ACCGCGTCGG CAGGGGCGGC AAATGCCATG


 


551
CCGATGCTCA AAATACCGAT GCCCAATGCG CTGATGAAGG AGGATTTTTT


 


601
CATGATTAAG TGTCCTAGTT TGAATATGAT GGCATACGTT TATTCGGCGG


 


651
CTTTTTCCGC ATTGCCGCCG TCGGCATTTT TCTCGGCAAA ACTCGTCATG


 


701
AATTTGCCGA TAAGGTTTTC CAGAACCATT GCAGAACTGG TTACGGAGAT


 


751
GGTGTCGCCG GCAGCAAGGT TTTCCGTGTC GCCGCCCTGC TGCAGCCCGA


 


801
TGTACTGCTC GCCCAAAAGT CCCGAAGTCA GGATTTGCGC GGAAACGTCG


 


851
CTGCTGAACT GATACTTGCC GTCCAAATCG AGGCGCACCC TCGCCTGATA


 


901
GGATTTCGGG TCAAGTCCGA TAGCGCCGAC GCGCCCGACC AATACGCCTG


 


951
CGGATTTGAC GGGGGCATTG ACCTTCAAAC CGCCGATGTC GCCGAAATCG


 


1001
GCATAAACGG CGTAAGTTTT GTCCGAACCG CCGAACGCCG CACCGCCGGC


 


1051
CACGCGGAAA GCGAGAAAGG CAACCGCCGC CGCGCCAATC AGGACGAACA


 


1101
GTCCGACCCA AAATTCCAAT ATGTTCTTTT TCATTAA






This corresponds to the amino acid sequence <SEQ ID 1584; ORF 543.a>:










a543.pep




1
MAYGLLAAVX SLQLXNQSVH AFRFDNFAEL VAVHGNQARA FDGDVVGTVF


 


51
TAALVGGEVH VDGFLPGXAD FGADDDFFAA FIDDXIVFDV DVGVF*FQHR


 


101
AGIGADQQGL KFFGQRLFLR VGRGAPRVAD RQCGHTLEIE IGNRIGFGFL


 


151
AGGVGITAF* DAQYLSGVLT DLVYRVGRGG KCHADAQNTD AQCADEGGFF


 


201
HD*VS*FEYD GIRLFGGFFR IAAVGIFLGK TRHEFADKVF QNHCRTGYGD


 


251
GVAGSKVFRV AALLQPDVLL AQKSRSQDLR GNVAAELILA VQIEAHPRLI


 


301
GFRVKSDSAD APDQYACGFD GGIDLQTADV AEIGINGVSF VRTAERRTAG


 


351
HAESEKGNRR RANQDEQSDP KFQYVLFH*






m543/a543 96.0% identity in 378 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1585>:










g544.seq




1
atgaaaaaaa tactcaccgc cgccgccgtc gcactgatcg gcatcctcct


 


51
cgccaccgtc ctcatccccg acagtaaaac cgcgcccgcc ttctccctgc


 


101
ccgacctgca cggaaaaacc gtttccaacg ccgacctgca aggcaaagtc


 


151
accctgatta atttttggtt tccctcctgt ccgggttgtg tgagcgaaat


 


201
gcccaaagtc accaaaacgg caaacgacta caaaaataaa gatttccaag


 


251
tcctcgccgt tgcccagccc atcgatccga tagaaagcgt ccgccaatac


 


301
gtcaaagact acggactgcc gtttaccgtc atttatgatg cggacaaagc


 


351
cgtcggacag gcattcggca cacaggttta tccgacttcc gtccttatcg


 


401
gcaaaaaagg cgaaatcctc aaaacttatg tcggcgaacc cgatttcggc


 


451
aaactctacc aagaaatcga taccgcgctg gcgcaatag






This corresponds to the amino acid sequence <SEQ ID 1586; ORF 544.ng>:










g544.pep




1
MKKILTAAAV ALIGILLATV LIPDSKTAPA FSLPDLHGKT VSNADLQGKV


 


51
TLINFWFPSC PGCVSEMPKV TKTANDYKNK DFQVLAVAQP IDPIESVRQY


 


101
VKDYGLPFTV IYDADKAVGQ AFGTQVYPTS VLIGKKGEIL KTYVGEPDFG


 


151
KLYQEIDTAL AQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1587>:










m544.seq




1
ATGAwAAAAA TACTCACCGC CGCCGTCGTC GCACTGATCG GCATCCTCCT


 


51
TGCCATCGTC CTCmTCCCCG ACAGCAAAAC CGCGCCCGCC TTCTCCmTGC


 


101
CCGACCTGCA CGGAAAAACC GTTTCCAACG CCGACCTGCA AGGCAAAGTA


 


151
ACCCTGATTA ATTTTTGGTT TCCCTCCTGT CCGGGTTGTG TGAGCGAwAT


 


201
GCCCAAAATC ATTAAAACGG CAAATGACTA TAAAAwCAAA AACTTCCAAG


 


251
TACTTGCCGT CGCCCAGCCC ATCGATCCGA TAGAAAGCGT CCGCCAATAT


 


301
GTCAAAGACT ACGGTTTGCC GTTTACCGTC ATGTATGATG CGGACAAAGC


 


351
TGTCGGACAG GCGTTCGGCA CACAGGTTTA TCCGACTTCC GTCCTTATCG


 


401
GCAAATAAGG CGAAATCTTC AAAACCTACG TCGGCGAACC CGATTTCGGC


 


451
AAACTCTACC AAGAAATCGA TACGCGCGTG GCGCAATAG






This corresponds to the amino acid sequence <SEQ ID 1588; ORF 544>:










m544.pep




1
MXKILTAAVV ALIGILLAIV LXPDSKTAPA FSXPDLHGKT VSNADLQGKV


 


51
TLINFWFPSC PGCVSXMPKI IKTANDYKXK NFQVLAVAQP IDPIESVRQY


 


101
VKDYGLPFTV MYDADKAVGQ AFGTQVYPTS VLIGK*GEIF KTYVGEPDFG


 


151
KLYQEIDTRV AQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 544 shows 90.7% identity over a 162 aa overlap with a predicted ORF (ORF 544.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1589>:










a544.seq




1
ATGAAAAAAA TACTCACCGC CGCCGTCGTC GCACTGATCG GCATCCTCCT


 


51
TGCCATCGTC CTCATCCCCG ACAGCAAAAC CGCGCCCGCT TTCTCCCTGT


 


101
CCGANCTGCA CGGAAAAANC GTTTNCAACG CCGACCTGCA AGGCNAAGTT


 


151
ANCCTGATTA ANTTTTGGTT TCCCTCCTGT CCGGGTTGTG TGAGCGAAAT


 


201
GNCCANAATC ATTAAAACGG CAAATGACTA TAAAAACAAA AACTTCCAAG


 


251
TCCTTGCCGT CGCCCAGCCC ATCGATCCGA TAGAAAGCGT CCGCCAATAT


 


301
GTCAAAGACT ACGGTTTGCC GTTTACCGTC ATGTATGATG CGGACAAAGC


 


351
TGTCGGACAG GCGTTCGGCA CACAGGTTTA TCCGACTTCC GTCCTTATCG


 


401
GCAAAAAAGG CGAAATCCTC AAAACTTATG TCGGCGAACC CGATTTCGGC


 


451
AAACTCTACC AAGAAATCGA TACCGCGCTG GCACAATAG






This corresponds to the amino acid sequence <SEQ ID 1590; ORF 544.a>:










a544.pep




1
MKKILTAAVV ALIGILLAIV LIPDSKTAPA FSLSXLHGKX VXNADLQGXV


 


51
XLIXFWFPSC PGCVSEMXXI IKTANDYKNK NFQVLAVAQP IDPIESVRQY


 


101
VKDYGLPFTV MYDADKAVGQ AFGTQVYPTS VLIGKKGEIL KTYVGEPDFG


 


151
KLYQEIDTAL AQ*






m544/a544 88.9% identity in 162 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1591>:










g547.seq




1
atgttcgtag ataacggatt taataaaacg gtagcgagtt ttgcccaaat


 


51
cgtcgaaact ttcgacgtat tcttctttag gaacgattgc gcctttttta


 


101
cgcagatgaa acagcggtgc ggttgggtct gctcgttggt atatctcgtt


 


151
gatatattta caagatgcgg cttcgagatt ccgaaccgct cctttaaaga


 


201
gcttgggctt ttgatacaga taagtctgtc ggaacgtttt aggactaatg


 


251
ccgaagtcga gatggatgcc cattacttcc ccttactcag aaaatattta


 


301
aaatttataa tgttacatat agttacaaat attagagttt tttgtgtgtg


 


351
cgtcaaggaa ttgttgacaa ttttagttaa aaatttgtct ccaaacggaa


 


401
aaaagcggtt tgttttttgt tgttaa






This corresponds to the amino acid sequence <SEQ ID 1592; ORF 547.ng>:










g547.pep




1
MFVDNGFNKT VASFAQIVET FDVFFFRNDC AFFTQMKQRC GWVCSLVYLV


 


51
DIFTRCGFEI PNRSFKELGL LIQISLSERF RTNAEVEMDA HYFPLLRKYL


 


101
KFIMLHIVTN IRVFCVCVKE LLTILVKNLS PNGKKRFVFC C*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1593>:










m547.seq




1
ATGTTCGTAG ATAACGGATT TAATAAAACG GTAGCGAGTT TTGCCCAAAT


 


51
CGTCGAAACT TTCGACGTAT TCTTCTTTAG GAACGATTGC GCCTTTTTTA


 


101
CGCAGATGAA ACAGCGGTGC GGTTGGGTCT GCTCGTTGGT ATATCTCGTT


 


151
GATATCTTTC CAAGATGCGG ATTCGAGATT CCGAACCGCT CCTTTAAAGA


 


201
GCTTGGGCTT TTGATACAGA TAAGTCTGTC GGAACGTTTT AGGACTAATG


 


251
CCGAAGTCGA GATGGATGCT CATTACTTCC CCTTACTCAG AAAATATTTA


 


301
AAATTTATAA TGTTACATAT ATTTACAAAT ATTAAAGTTT TTTwTTGTGT


 


351
GTGCGTCAAG GAATTGTTGA CAATTTTAGT TAAAAATTTG TCTCCAAACG


 


401
GAAAAAAGCG GTTTGTTTTT TGTTGTTAA






This corresponds to the amino acid sequence <SEQ ID 1594; ORF 547>:










m547.pep




1
MFVDNGFNKT VASFAQIVET FDVFFFRNDC AFFTQMKQRC GWVCSLVYLV


 


51
DIFPRCGFEI PNRSFKELGL LIQISLSERF RTNAEVEMDA HYFPLLRKYL


 


101
KFIMLHIFTN IKVFXCVCVK ELLTILVKNL SPNGKKRFVF CC*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 547 shows 97.2% identity over a 142 aa overlap with a predicted ORF (ORF 547.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1595>:










a547.seq




1
ATGTTCGTAG ATAACGGATT TAATAAAACG GTAGCGAGTT TTGCCCAAAT


 


51
CGTCGAAACT TTCGACGTAT TCTTCTTTAG GAACAATTGC ACCTTTTTTA


 


101
CGCAGATGAA ACAGCGGTGC GGTTGGGTCT GCTCGTTGGT ATATCTCGTT


 


151
GATATCTTTC CAAGATGCGG CTTCGAGATT CCGAACCGCT CCTTTAAAGA


 


201
GCTTGGGCTT TTGATACAGA TAAGTCTGTC GGAACGTTTT AGGACTAATG


 


251
CCGAAGTCGA GATAGATGCT CATTACTTCC CCTTACTCAG AAAATATTTA


 


301
AAATTTATAA TGTTACATAT ATTTACAAAT ATTAAAGTTT TTTT.TGTGT


 


351
GTGCGTCAAG GAATTGTTGA CAATTTTAGT T






This corresponds to the amino acid sequence <SEQ ID 1596; ORF 547.a>:










a547.pep




1
MFVDNGFNKT VASFAQIVET FDVFFFRNNC TFFTQMKQRC GWVCSLVYLV


 


51
DIFPRCGFEI PNRSFKELGL LIQISLSERF RTNAEVEIDA HYFPLLRKYL


 


101
KFIMLHIFTN IKVFXCVCVK ELLTILV






m547/a547 97.6% identity in 127 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1597>:










g548.seq




1
atgttttccg taccgcgttc ctttttgccg ggcgttttcg tacttgccgc


 


51
gcttgccgcc tgcaaacctc aagacaacag tgcggcgcaa gccgcttctt


 


101
caagtgcatc cgcgccggct gcggaaaatg cggcaaagcc gcaaacgcgc


 


151
ggtacggata tgcgtaagga agacatcggc ggcgatttca cactgaccga


 


201
cggcgaaggc aagcctttca gcctgagcga tttgaaaggc aaggtcgtga


 


251
ttctgtcttt cggctttacg cactgtcccg atgtctgccc gacagggctt


 


301
ttgacgtaca gcgacacttt gaagcagttg ggcgggcagg ctaaggacgt


 


351
gaaagtggtg ttcgtcagca tcgatccgga acgcgacacg cctgaaatca


 


401
tcggcaagta tgccaaacag ttcaatccgg actttatcgg tctgacggca


 


451
acgggcggcc aaaacctgcc ggtcatcaag cagcaatacc gcgtggtttc


 


501
tgccaaaatc aatcaaaaag acgacagcga aaactatttg gtcgaccact


 


551
cttccggtgc gtatcttatc gataaaaacg gtgaggttgc cattttctcg


 


601
ccttacggaa gcgagccgga aacgattgct gccgatgtaa ggaccctgct


 


651
ctga






This corresponds to the amino acid sequence <SEQ ID 1598; ORF 548.ng>:










g548.pep




1
MFSVPRSFLP GVFVLAALAA CKPQDNSAAQ AASSSASAPA AENAAKPQTR


 


51
GTDMRKEDIG GDFTLTDGEG KPFSLSDLKG KVVILSFGFT HCPDVCPTGL


 


101
LTYSDTLKQL GGQAKDVKVV FVSIDPERDT PEIIGKYAKQ FNPDFIGLTA


 


151
TGGQNLPVIK QQYRVVSAKI NQKDDSENYL VDHSSGAYLI DKNGEVAIFS


 


201
PYGSEPETIA ADVRTLL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1599>:










m548.seq




1
ATGTTTTCCG TACCGCGTTC CTTTTTGCCG GGCGTTTTCG TACTTGCCGC


 


51
GCTTGCCGCC TGCAAACCTC AAGACAACAG TGCGGCGCAA GTCGCTTCTT


 


101
CAAGTGCATC CGCGTCGGCT GCGGAAAATG CGGCAAAGCA AnACACGCGC


 


151
GGTACGGATA TGCGTAAGGA AGACATCGGC GGCGATTTCA CGCTGACCGA


 


201
CGGCGAAGGC AAGCCTTTCA ACCTGAGCGA TTTGAAAGGC AAGGTCGTGA


 


251
TTCTGTCTTT CGGCTTTACG CACTGTCCCG ATGTCTGCCC GACAGAGCTT


 


301
TTGACGTACA GCGACACGTT GAAGCAGTTG GGCGGGCAGG CTAAGGACGT


 


351
GAAAGTGGTG TTCGTCAGCA TCGATCCGGA ACGCGACACG CCTGAAATCA


 


401
TCGGCAAGTA TGCCAAACAG TTCAATCCGG ACTTTATCGs TCTGACGGCA


 


451
ACGGGCGGCC AAAACCTGCC GGTCATCAAG CAGCAATACc GCGTGGTTTC


 


501
TGCCAAAGTC AATCAAAAmG ACGACAGCGA AAACTATTTG GTCGACCACT


 


551
CTTCCGGTGC GTATCTCATC GACAAAAACG GTGAGGTTGC CATTTTCTCG


 


601
CCTTACGGAA GCGAGCCGGA AACGATTGCT GCCGATGTAA GGACCCTGCT


 


651
CTGA






This corresponds to the amino acid sequence <SEQ ID 1600; ORF 548>:










m548.pep




1
MFSVPRSFLP GVFVLAALAA CKPQDNSAAQ VASSSASASA AENAAKQXTR


 


51
GTDMRKEDIG GDFTLTDGEG KPFNLSDLKG KVVILSFGFT HCPDVCPTEL


 


101
LTYSDTLKQL GGQAKDVKVV FVSIDPERDT PEIIGKYAKQ FNPDFIXLTA


 


151
TGGQNLPVIK QQYRVVSAKV NQXDDSENYL VDHSSGAYLI DKNGEVAIFS


 


201
PYGSEPETIA ADVRTLL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 548 shows 95.9% identity over a 217 aa overlap with a predicted ORF (ORF 548.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1601>:










a548.seq




1
ATGTTTTCCG TACCGCGTTC CTTTTTGCCG GGCGTTTTCG TACTTGCCGC


 


51
GCTTGCCGCC TGCAAACCTC AAGACAACAG TGCGGCGCAA GTCGCTTCTT


 


101
CAAGTGCATC CGCGTCGGCT GCGGAAAATG CGGCAAAGCC GCAAACGCGC


 


151
GGTACGGATA TGCGTAAGGA AGACATCGGC GGCGATTTCA CGCTGACCGA


 


201
CGGCGAAGGC AAGCCTTTCA ACCTGAGCGA TTTGAAAGGC AAGGTCGTGA


 


251
TTCTGTCTTT CGGCTTTACG CACTGTCCCG ATGTCTGCCC GACAGAGCTT


 


301
TTGACGTACA GCGACACGTT GAAGCAGTTG GGCGGGCAGG CTAAGGACGT


 


351
GAAAGTGGTG TTCGTCAGCA TCGATCCGGA ACGCGACACG CCTGAAATCA


 


401
TCGGCAAGTA TGCCAAACAG TTCAATCCGG ACTTTATCGG TCTGACGGCA


 


451
ACGGGCGACC AAAACCTGCC GGTCATCAAG CAGCAATACC GCGTGGTTTC


 


501
TGCCAAAGTC AATCAAAAAG ACGACAGCGA AAACTATTTG GTCGACCACT


 


551
CTTCCGGTGC GTATCTCATC GACAAAAACG GTGAGGTTGC CATTTTCTCG


 


601
CCTTACGGAA GCGAGCCGGA AACGATTGCT GCCGATGTAA GGACCCTGCT


 


651
CTGA






This corresponds to the amino acid sequence <SEQ ID 1602; ORF 548.a>:










a548.pep




1
MFSVPRSFLP GVFVLAALAA CKPQDNSAAQ VASSSASASA AENAAKPQTR


 


51
GTDMRKEDIG GDFTLTDGEG KPFNLSDLKG KVVILSFGFT HCPDVCPTEL


 


101
LTYSDTLKQL GGQAKDVKVV FVSIDPERDT PEIIGKYAKQ FNPDFIGLTA


 


151
TGDQNLPVIK QQYRVVSAKV NQKDDSENYL VDHSSGAYLI DKNGEVAIFS


 


201
PYGSEPETIA ADVRTLL*






m548/a548 97.7% identity in 217 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1603>:










g550.seq




1
atgataacgg acaggtttca tctctttcat tttccagtat ctttcattta


 


51
tcaatctgac aacaaaatgc cgcctgaaaa cagttcagac ggcattttaa


 


101
ccacaaacgg cttacagctt ccattcgccc aacttggcag cgtaagcttc


 


151
caaatctgca atcggacggg ttgccacgcc gctttccatc gctgctttgg


 


201
cggcagccgt agcgacgcga ggcagcaggc gggaatcgaa cggagtagga


 


251
atcaggtatt ccgcgccgaa ttcgaatttc ttaccgtaag cggcaaccac


 


301
ttcttcggtt acttcttcca tcgccaaatc tgccaaagca tacacgcagg


 


351
cgcgtttcat ttcttcgttg atggtggttg cgccgacatc caacgcgccc


 


401
cggaagatga acgggaagca caatacgttg ttcacttggt tcgggaagtc


 


451
ggagcggccg gtaccgataa ccacgtccgg acgggtttct ttcgccagcg


 


501
gcggcaggat ttccggattc gggttggcca tggcgaacac gatgggtttt


 


551
tcgttcatcg tgttcaacat ttcaggcgtc agcaggtttg cgccggagag


 


601
gcccaagaag atgtctttgc ctttaaccgc atcggcaagt acgcgccggc


 


651
cgttgtcttc aacggcgtag aattttttgg attcgtccat gcggtctttg


 


701
tcttcgcggg tttggtaaat cacgcctttg gagttgcaaa cggttacgtt


 


751
ttcacgtttc aagcccaaat ccagcagttg gttcaggcag gcaatcgcgg


 


801
cggcacctgc gccggagcac accaaagtcg cttcttcgat tttacggccg


 


851
gtataacgca gggcgttcaa tacggcggcg gcggtaatga tggccgtgcc


 


901
gtgctggtca tcatgaaata cggggatttt gcagcgtttg cgtaa






This corresponds to the amino acid sequence <SEQ ID 1604; ORF 550.ng>:










g550.pep




1
MITDRFHLFH FPVSFIYQSD NKMPPENSSD GILTTNGLQL PFAQLGSVSF


 


51
QICNRTGCHA AFHRCFGGSR SDARQQAGIE RSRNQVFRAE FEFLTVSGNH


 


101
FFGYFFHRQI CQSIHAGAFH FFVDGGCADI QRAPEDEREA QYVVHLVREV


 


151
GAAGTDNHVR TGFFRQRRQD FRIRVGHGEH DGFFVHRVQH FRRQQVCAGE


 


201
AQEDVFAFNR IGKYAPAVVF NGVEFFGFVH AVFVFAGLVN HAFGVANGYV


 


251
FTFQAQIQQL VQAGNRGGTC AGAHQSRFFD FTAGITQGVQ YGGGGNDGRA


 


301
VLVIMKYGDF AAFA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1605>:









m550.seq (partial)










1
..GACGGCATCG GCAAGCACGC GCTGGCCGTT GTCTTCAATG GCGTAGAACT



 


51
  GTTTGGACTC GTCCATACGG TCTTTGTCTT CGCGGGTTTG GTAAATCACG


 


101
  CCTTTGGAGT CGCAAACGGT CACGTTTTCG CGTTTCAAGC CCAAATCCAG


 


151
  CAATTGGwTC AAGCAGGCAA TCGCGGCCGC ACCTGCGCCG GAACACACCA


 


201
  AAGTCGCTTC TTCGATTTTA CGGCCGGTAA AACGCAkGGC GTTCAATACG


 


251
  GCGGCGGCGG TAATGATGGC CGTGCCGTGC TGGTCGTCGT GGAATACGGG


 


301
  GATTTTGCAG CGTTTGCGTA A






This corresponds to the amino acid sequence <SEQ ID 1606; ORF 550>:









m550.pep (partial)










1
..DGIGKHALAV VFNGVELFGL VHTVFVFAGL VNHAFGVANG HVFAFQAQIQ



 


51
  QLXQAGNRGR TCAGTHQSRF FDFTAGKTXG VQYGGGGNDG RAVLVVVEYG


 


101
  DFAAFA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 550 shows ——————% identity over a —————— aa overlap with a predicted ORF (ORF 550.ng) from N. gonorrhoeae:





The following partial DNA sentience was identified in N. meningitides <SEQ ID 1607>:










a550.seq




1
CTATATCAAT CTGACAGCAA AATGCCGCCT GAAAACAGTT CAGACGGCAT


 


51
TTTAACCGCA AACGGCTTAC AGCTTCCATT CGCTCAGCTT GGCAGCGTAA


 


101
GCTTCCAAAT CTGCAATCGG ACGGGTTGCC ACGCCGCTTT CCATCGCTGC


 


151
TTTGGCGGCA GCCGTAGCAA CGCGCGGCAG CAGGCGGGAA TCGAACGGAG


 


201
TCGGAATCAG GTATTCCGCG CCGAATTCAA ATTTCTTACC GTAAGCGGCA


 


251
ACCACTTCTT CGGTTACCTC TTCCATCGCC AAATCCGCCA AAGCATACAC


 


301
GCAGGCGCGT TTCATTTCTT CGTTGATGGT CGTCGCGCCG ACATCCAACG


 


351
CACCGCGGAA GATGAACGGG AAGCACAATA CATTGTTCAC TTGGTTCGGG


 


401
AAGTCGGAGC GGCCGGTACC GATAACCACG TCCGGACGGG TTTCTTTCGC


 


451
CAGCGGCGGC AGGATTTCCG GATTCGGGTT GGCCATAGCG AACACGATGG


 


501
GTTTTTCGTT CATGGTGTTC AGTATTTCAG GCGTCAGCAG GTTCGCGCCG


 


551
GAGAGGCCCA AGAAGATGTC TTTGCCTTTG ACGGCATCGG CAAGCACGCG


 


601
CTGGCCGTTG TCTTCAATGG CGTAGAACTG TTTGGACTCG TCCATACGGT


 


651
CTTTGTCTTC GCGGGTTTGG TAAATCACGC CTTTGGAGTC GCAAACGGTC


 


701
ACGTTTTCGC GTTTCAAGCC CAAATCCAGC AATTGGTTCA AGCAGGCAAT


 


751
CGCGGCCGCA CCTGCGCCGG AACACACCAA AGTCGCTTCT TCGATTTTAC


 


801
GGCCGGTAAA ACGCAGGGCG TTCAATACGG CAGCGGCGGT AATGATGGCC


 


851
GTGCCGTGCT GGTCGTCGTG GAATACGGGG ATTTTGCAGC GTTTGCGTAA






This corresponds to the amino acid sequence <SEQ ID 1608; ORF 550.a>:










a550.pep




1
LYQSDSKMPP ENSSDGILTA NGLQLPFAQL GSVSFQICNR TGCHAAFHRC


 


51
FGGSRSNARQ QAGIERSRNQ VFRAEFKFLT VSGNHFFGYL FHRQIRQSIH


 


101
AGAFHFFVDG RRADIQRTAE DEREAQYIVH LVREVGAAGT DNHVRTGFFR


 


151
QRRQDFRIRV GHSEHDGFFV HGVQYFRRQQ VRAGEAQEDV FAFDGIGKHA


 


201
LAVVFNGVEL FGLVHTVFVF AGLVNHAFGV ANGHVFAFQA QIQQLVQAGN


 


251
RGRTCAGTHQ SRFFDFTAGK TQGVQYGSGG NDGRAVLVVV EYGDFAAFA*






m550/a550 97.2% identity in 106 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1609>:










g552.seq




1
atgaagctga aaaccttgtt attgcccttc gccgcactgg cattgtgtgc


 


51
caacgcattt gccgccccgc ccggcgacgc gtcgttggca cgttggctgg


 


101
atacgcagaa tttcgaccgg gatatagaaa aaaatatgat tgaaggcttt


 


151
aatgccggat ttaaaccgta tgcggacaaa gcccttgccg aaatgccgga


 


201
agcgaaaaaa gatcaggcgg cagaagcctt taatcgttat cgtgagaatg


 


251
ttttgaaaga tttgattacg cccgaagtga aacaggctgt ccgcaatacc


 


301
ttattgaaga atgcccgtga aatatacacg caagaagaaa ttgacggcat


 


351
gattgccttt tacggttcgc ctgtcggtca gtccgtcgtt gccaaaaatc


 


401
cgcgcttaat caagaaatcg atgagtgaaa tagcggtatc ttggactgca


 


451
ttgtcaggga aaatcgcgcg acatcatctg cccgagttta cggaagagtt


 


501
acggcgcatc atctgcggcg gtatagtgga ttaa






This corresponds to the amino acid sequence <SEQ ID 1610; ORF552.ng>:










g552.pep




1
MKLKTLLLPF AALALCANAF AAPPGDASLA RWLDTQNFDR DIEKNMIEGF


 


51
NAGFKPYADK ALAEMPEAKK DQAAEAFNRY RENVLKDLIT PEVKQAVRNT


 


101
LLKNAREIYT QEEIDGMIAF YGSPVGQSVV AKNPRLIKKS MSEIAVSWTA


 


151
LSGKIARHHL PEFTEELRRI ICGGIVD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1611>:









m552.seq (partial)










1
..ATTAAACTGA AAACCTTGTT ATTGCCCTTC GCCACGCTGG CATTGTGCAC



 


51
  CAATGCTTTT GCCGCCCCGC CCAGCGACGC GTCGTTGGCG CGTTGGCTGG


 


101
  ATACGCAGAA TTTTGACCGG GATATAGAAA AAAATATGAT TGAGGGCTTT


 


151
  AATGCCGGAT TTAAACCGTA TGCGGACAAA GCCCTTGCCG AAATGCCGGA


 


201
  AGCGAAAAAA GATCAGGCGG CAGAAGCCTT TAACCGTTAT CGTGAGAATG


 


251
  TTTTGAAAGA TTTGATTACG CCCGAAGTGA AACAGGCTGT CCGCAATACT


 


301
  TTATTGAAGA ATGCCCGTGA GATATACACG CAAGAAGAAA TTGACGGCAT


 


351
  GATTGCCTTT TACGGTTCGC CTGTCGGTCA GTCCGTCGTT GCCAAAAATC


 


401
  CGCGCTTAAT CAAGAAATCG ATGAGTGAAA TAGCGGTATC TTGGACTGCA


 


451
  TTGTCAGGGA AAATCGCGCA ACATCATCTG CCCGAGTTTA CGGAAGAGTT


 


501
  GCGGCGCATC ATCTGCGGCG GTAAAAATCC CGATGCGGGC TGTAAACAAG


 


551
  CCGGACAGGT TGGGAAAAGG CATCAGAAAT AA






This corresponds to the amino acid sequence <SEQ ID 1612; ORF 552>:









m552.pep (partial)










1
..IKLKTLLLPF ATLALCTNAF AAPPSDASLA RWLDTQNFDR DIEKNMIEGF



 


51
  NAGFKPYADK ALAEMPEAKK DQAAEAFNRY RENVLKDLIT PEVKQAVRNT


 


101
  LLKNAREIYT QEEIDGMIAF YGSPVGQSVV AKNPRLIKKS MSEIAVSWTA


 


151
  LSGKIAQHHL PEFTEELRRI ICGGKNPDAG CKQAGQVGKR HQK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 552 shows 97.1% identity over a 174 aa overlap with a predicted ORF (ORF 552.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1613>:










a552.seq




1
ATTAAACTGA AAACCTTGTT ATTGCCCTTC GCCACGCTGG CATTGTGCAC


 


51
CAATGCTTTT GCCGCCCCGC CCAGCGACGC GTCGTTGGCG CGTTGGCTGG


 


101
ATACGCAGAA TTTTGACCGG GATATAGAAA AAAATATGAT TGAGGGCTTT


 


151
AATGCCGGAT TTAAACCGTA TGCGGACAAA GCCCTTGCCG AAATGCCGGA


 


201
AGCGAAAAAA GATCAGGCGG CAGAAGCCTT TAACCGTTAT CGTGAGAATG


 


251
TTTTGAAAGA TTTGATTACG CCCGAAGTGA AACAGGCTGT CCGCAATACT


 


301
TTATTGAAGA ATGCCCGTGA GATATACACG CAAGAAGAAA TTGACGGCAT


 


351
GATTGCCTTT TACGGTTCGC CTGTCGGTCA GTCCGTCGTT GCCAAAAATC


 


401
CGCGCTTAAT CAAGAAATCG ATGAGTGAAA TAGCGGTATC TTGGACTGCA


 


451
TTGTCAGGGA AAATCGCGCA ACATCATCTG CCCGAGTTTA CGGAAGAGTT


 


501
GCGGCGCATC ATCTGCGGCG GTAAAAATCC CGATGCGGGC TGTAAACAAG


 


551
CCGGACAGGT TGGGAAAAGG CATCAGAAAT AA






This corresponds to the amino acid sequence <SEQ ID 1614; ORF 552.a>:










a552.pep




1
IKLKTLLLPF ATLALCTNAF AAPPSDASLA RWLDTQNFDR DIEKNMIEGF


 


51
NAGFKPYADK ALAEMPEAKK DQAAEAFNRY RENVLKDLIT PEVKQAVRNT


 


101
LLKNAREIYT QEEIDGMIAF YGSPVGQSVV AKNPRLIKKS MSEIAVSWTA


 


151
LSGKIAQHHL PEFTEELRRI ICGGKNPDAG CKQAGQVGKR HQK*






m552/a552 100.0% identity in 193 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1615>:










m552-1.seq




1
TTGAATATTA AACTGAAAAC CTTGTTATTG CCCTTCGCCA CGCTGGCATT


 


51
GTGCACCAAT GCTTTTGCCG CCCCGCCCAG CGACGCGTCG TTGGCGCGTT


 


101
GGCTGGATAC GCAGAATTTT GACCGGGATA TAGAAAAAAA TATGATTGAG


 


151
GGCTTTAATG CCGGATTTAA ACCGTATGCG GACAAAGCCC TTGCCGAAAT


 


201
GCCGGAAGCG AAAAAAGATC AGGCGGCAGA AGCCTTTAAC CGTTATCGTG


 


251
AGAATGTTTT GAAAGATTTG ATTACGCCCG AAGTGAAACA GGCTGTCCGC


 


301
AATACTTTAT TGAAGAATGC CCGTGAGATA TACACGCAAG AAGAAATTGA


 


351
CGGCATGATT GCCTTTTACG GTTCGCCTGT CGGTCAGTCC GTCGTTGCCA


 


401
AAAATCCGCG CTTAATCAAG AAATCGATGA GTGAAATAGC GGTATCTTGG


 


451
ACTGCATTGT CAGGGAAAAT CGCGCAACAT CATCTGCCCG AGTTTACGGA


 


501
AGAGTTGCGG CGCATCATCT GCGGCGGTAA AAATCCCGAT GCGGGCTGTA


 


551
AACAAGCCGG ACAGGTTGGG AAAAGGCATC AGAAATAA






This corresponds to the amino acid sequence <SEQ ID 1616; ORF 552-1>:










m552-1.pep




1
LNIKLKTLLL PFATLALCTN AFAAPPSDAS LARWLDTQNF DRDIEKNMIE


 


51
GFNAGFKPYA DKALAEMPEA KKDQAAEAFN RYRENVLKDL ITPEVKQAVR


 


101
NTLLKNAREI YTQEEIDGMI AFYGSPVGQS VVAKNPRLIK KSMSEIAVSW


 


151
TALSGKIAQH HLPEFTEELR RIICGGKNPD AGCKQAGQVG KRHQK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1617>:










a552-1.seq




1
TTGAATATTA AACTGAAAAC CTTGTTATTG CCCTTCGCCA CGCTGGCATT


 


51
GTGCACCAAT GCTTTTGCCG CCCCGCCCAG CGACGCGTCG TTGGCGCGTT


 


101
GGCTGGATAC GCAGAATTTT GACCGGGATA TAGAAAAAAA TATGATTGAG


 


151
GGCTTTAATG CCGGATTTAA ACCGTATGCG GACAAAGCCC TTGCCGAAAT


 


201
GCCGGAAGCG AAAAAAGATC AGGCGGCAGA AGCCTTTAAC CGTTATCGTG


 


251
AGAATGTTTT GAAAGATTTG ATTACGCCCG AAGTGAAACA GGCTGTCCGC


 


301
AATACTTTAT TGAAGAATGC CCGTGAGATA TACACGCAAG AAGAAATTGA


 


351
CGGCATGATT GCCTTTTACG GTTCGCCTGT CGGTCAGTCC GTCGTTGCCA


 


401
AAAATCCGCG CTTAATCAAG AAATCGATGA GTGAAATAGC GGTATCTTGG


 


451
ACTGCATTGT CAGGGAAAAT CGCGCAACAT CATCTGCCCG AGTTTACGGA


 


501
AGAGTTGCGG CGCATCATCT GCGGCGGTAA AAATCCCGAT GCGGGCTGTA


 


551
AACAAGCCGG ACAGGTTGGG AAAAGGCATC AGAAATAA






This corresponds to the amino acid sequence <SEQ ID 1618; ORF 552-1.a>:










a552-1.pep




1
LNIKLKTLLL PFATLALCTN AFAAPPSDAS LARWLDTQNF DRDIEKNMIE


 


51
GFNAGFKPYA DKALAEMPEA KKDQAAEAFN RYRENVLKDL ITPEVKQAVR


 


101
NTLLKNAREI YTQEEIDGMI AFYGSPVGQS VVAKNPRLIK KSMSEIAVSW


 


151
TALSGKIAQH HLPEFTEELR RIICGGKNPD AGCKQAGQVG KRHQK*






a552-1/m552-1 100.0% identity in 195 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1619>:










g553.seq




1
atggattatc tgcaaaacct gtctttgggc ttgacaaaaa agctgcccgt


 


51
tatactgcaa acagaagtag cggagtgtgg cttggcatgt ctagcggctg


 


101
tggccggatt ttatggtttc tatacggatt tgcgcgcact gcgttcaaaa


 


151
tactgtctgt cacttaaggg tgagaatttg gcagatattg ttcgttttgc


 


201
tgatgatatg gggctgacgg gacgggcgtt gaggctggat ttagacgaat


 


251
tgggcagttt gcgcctgccc tgtattctac attgggattt gaatcatttt


 


301
gtggtgctgg aatcggtatc ttcggacggg gctgccgtca tggatccggc


 


351
ttcgggacga cgcaaagtca agacggagga aatatcgcgc aagtttacgg


 


401
gaattgcttt ggaactgtgg ccaaacacgc gtttcgaggc aggggaagaa


 


451
aagcaggaaa tccgcatcct acccatgttg cgcgggattt ctgggctggg


 


501
gcggacattg tttcagcttt tggctttggc agcagcaatg gaagtgtttg


 


551
cttttttaca aaacgtcagc ttcaagatcg gacgtggtga atcgcttgcg


 


601
ttaatcggac gatcgggctg cggtaaatcg acacttttgg atattttaag


 


651
cggcaatcta cctcccgaat caggcaaagt catgataaat gggcacgaca


 


701
tttacagctt accgccacct tttattccgc aatttgagtg cgatggtcaa


 


751
ggcaggacga tgttttatag tggattaaat ttaaaccggt ag






This corresponds to the amino acid sequence <SEQ ID 1620; ORF 553.ng>:










g553.pep




1
MDYLQNLSLG LTKKLPVILQ TEVAECGLAC LAAVAGFYGF YTDLRALRSK


 


51
YCLSLKGENL ADIVRFADDM GLTGRALRLD LDELGSLRLP CILHWDLNHF


 


101
VVLESVSSDG AAVMDPASGR RKVKTEEISR KFTGIALELW PNTRFEAGEE


 


151
KQEIRILPML RGISGLGRTL FQLLALAAAM EVFAFLQNVS FKIGRGESLA


 


201
LIGRSGCGKS TLLDILSGNL PPESGKVMIN GHDIYSLPPP FIPQFECDGQ


 


251
GRTMFYSGLN LNR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1621>:









m553.seq (partial)










1
ATGGATTATT TATCAAGACT GTCCTTTGGA TTTAACAAAA AGCTACCTGT



 


51
CATTCTGCAA ACAGAAGTTG CTGAATGTGG TTTAGCATGC CTGACATCCA


 


101
TCTTGTCCTA TTATGGCTTT CACACTGATT TAAGAACGTT ACGCCAAAAA


 


151
TACACCCTGT CATTAAAGGG CGCAAATCTT GCAGACATCA TGAGATTTGG


 


201
CAATGAAATG AATTTAACGC CACGAGCTTT GCGTTTAGAG TTAGATGAGC


 


251
TGTCAAATTT ACAACTACCC TGCATTCTCC ATTGGAACTT AAACCATTTT


 


301
GTTGTACTTT GTTCCATTTC CAAAGACAGT ATCGTCATTA TGGACCCTGC


 


351
TGTCGGTATG CGAAAAATCA AAATGGACGA AGTTTCACAA AAATTCACAG


 


401
GGATTGCCCT AGAATTATTC CCCAATACCC ATTTTGAAGA GAAAAAAGAA


 


451
ACAAAGAAAA TCAAAATATT ATCTCTATTA AGGGGGGG.T CAGGCTTAAA


 


501
ACGCTCTTTA ATTCAAATGC TTATATTAGC TATTTCTTTG GAAGTCTTTG


 


551
CATTG...






This corresponds to the amino acid sequence <SEQ ID 1622; ORF 553>:









m553.pep (partial)










1
MDYLSRLSFG FNKKLPVILQ TEVAECGLAC LTSILSYYGF HTDLRTLRQK



 


51
YTLSLKGANL ADIMRFGNEM NLTPRALRLE LDELSNLQLP CILHWNLNHF


 


101
VVLCSISKDS IVIMDPAVGM RKIKMDEVSQ KFTGIALELF PNTHFEEKKE


 


151
TKKIKILSLL RGXSGLKRSL IQMLILAISL EVFAL...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 553 shows 65.5% identity over a 185 aa overlap with a predicted ORF (ORF 553.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1623>:










a553.seq




1
ATGCCCCATC TGCAAAACCT GTCTTTGGGC TTAAAGAAAA AGCTGCCTGT


 


51
TATCCTGCAA ACAGAAATAT CAGAATGCGG CTTGGCATGT CTGGCGGCTG


 


101
TGGCGGGATT TCATGGTTTC CATACGAATT TACGCGCACT GCGTTCAAAA


 


151
TAC






This corresponds to the amino acid sequence <SEQ ID 1624; ORF 553.a>:










a553.pep




1
MPHLQNLSLG LKKKLPVILQ TEISECGLAC LAAVAGFHGF HTNLRALRSK


 


51
Y






m553/a553 62.7% identity in 51 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1625>:










g554.seq..




1
atgacagcac ataaaatcct gcccgtcctt cttcccatca tcttaggcgt


 


51
ttctcacgca acggctgcat cgcccgcgcc caacagaccg acggtacacg


 


101
ccgcccccac gctccaaaca cccgaaaccc tcacggcggc acacatcgtt


 


151
atcgaccttc aaagcaggca gactttatcc gccaaaaaca ccaatacccc


 


201
tgtcgaaccg gcggcactaa cccaactgat gaccgcatat ttggttttca


 


251
aaaacatgaa atcgggaaat atccaatctg aagaaaactt aaaaataccc


 


301
gaatccgcat gggcttcaga aggaagcaga atgtttgtac gtcccggcga


 


351
tacggtcagc accgacaaac tcttaaaagg catgattgcc ctatgcgcaa


 


401
acgatgccgc cctaaccctt gccgaccggc tgggcaacgg ctcgattgaa


 


451
aattttgtgc aacaaatgaa caaagaagcc cgacgcttgg gcatgaagaa


 


501
caccgtattc aaaaacccga caggcttggg tagagaagga caggtttcca


 


551
ccgccaaaga cctctccctg ctgtctgaag cattgatgcg cgactttccg


 


601
gaatattacc cgctgttttc catcaaatcg ttcaagtttg aaaacataga


 


651
acaaaacaac cgcaatatcc ttttatatag ggacaacaat gtaaacggcc


 


701
tgaaagccgg gcacacagaa agcggcggct acaaccttgc cgtgtcatac


 


751
tccggcaacg gcaggcacat ccttgtcatc acactaggtt cggaatcggc


 


801
ggaaacccgc gcatcggaca acagcaagct gctgaaccgg gcattgcagg


 


851
ccttcgatac gcccaaaata tatccgaaag gcaaaaccgt tgcccaaatc


 


901
caaatttccg gaggcagcaa aaaaaccgtc cgcgcaggct tcctcaaaga


 


951
agcctacatc actctgccac ataaagaagc gaaaatggca gaacagattt


 


1001
tggaaaccat acagccgatt cccgccccgg taaaaaaagg gcagatttta


 


1051
ggaaaaatca aaatcaggca aaacggacat accattgccg aaaaagaaat


 


1101
cgtcgcactg gaaaacgtag aaaaaagaag ccggtggcaa aggctttgga


 


1151
cgcgtctgac agggcagtaa






This corresponds to the amino acid sequence <SEQ ID 1626; ORF 554.ng>:










g554.pep..




1
MTAHKILPVL LPIILGVSHA TAASPAPNRP TVHAAPTLQT PETLTAAHIV


 


51
IDLQSRQTLS AKNTNTPVEP AALTQLMTAY LVFKNMKSGN IQSEENLKIP


 


101
ESAWASEGSR MFVRPGDTVS TDKLLKGMIA LCANDAALTL ADRLGNGSIE


 


151
NFVQQMNKEA RRLGMKNTVF KNPTGLGREG QVSTAKDLSL LSEALMRDFP


 


201
EYYPLFSIKS FKFENIEQNN RNILLYRDNN VNGLKAGHTE SGGYNLAVSY


 


251
SGNGRHILVI TLGSESAETR ASDNSKLLNR ALQAFDTPKI YPKGKTVAQI


 


301
QISGGSKKTV RAGFLKEAYI TLPHKEAKMA EQILETIQPI PAPVKKGQIL


 


351
GKIKIRQNGH TIAEKEIVAL ENVEKRSRWQ RLWTRLTGQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1627>:










m554.seq..




1
ATGACAGCAC ATAAAATCCT GCCCGTCCTG CTTTCCATCA TCTTAGGCGT


 


51
TTCTCACGCA ACGGCTGCAT CGCCCGCGCC CAACAGACCG ACGGTACACG


 


101
CCGCCCCCAC GTTCCAAACA CCCGAAACCC TCACAGCGGC ACACATCGTT


 


151
ATCGACCTTC AAAGCAAACA GATTTTATCC GCCAAAAACA TCAATACCCC


 


201
TGTTGAACCG GCGGCACTAA CCCAACTGAT GACCGCATAT CTGGTTTTCA


 


251
AAAACATGAA ATCGGGCAAT ATCCAATCTG AAGAAAACTT AAAAATACCC


 


301
GAATCCGCAT GGGCTTCAGA AGGAAGCAGA ATGTTTGTAC GTCCCGGCGA


 


351
TACGGTCAGC ACCGACAAAC TCTTAAAAGG CATGATTGCA CTATCCGCAA


 


401
ACGATGCCGC CCTAACCCTT GCCGGCCGGC TGGGCAACGG CTCGATTGAA


 


451
AATTTTGTGC AACAAATGAA CAAAGAAGCC CGACGCTTGG GCATGAAGAA


 


501
CACTGTATTC AAAAACCCGA CAGGCTTGAG TAGAGAAGGA CAGGTTTCCA


 


551
CCGCCAAAGA CGTCGCACTG CTGTCTGAAG CATTGATGCG CGACTTTCCG


 


601
GAATATTACC CGCTGTTTTC CATCAAATCT TTCAAATTCA AAAATATAGA


 


651
ACAAAACAAC CGCAATATCC TTTTATATAG GGACAACAAT GTAAACGGTC


 


701
TGAAAGCCGG ACACACAGAA AGCGGCGGCT ACAACCTTGC CGTGTCATAC


 


751
TCCGGCAACG GCAGGCACAT CCTTGTCATC ACATTGGGTT CGGAATCGGC


 


801
GGAAACACGC GCATCAGACA ACAGCAAGCT GCTGAACTGG GCATTGCAGG


 


851
CCTTCGATAC GCCCAAAATA TATCCGAAAG GCAAAACCGT TGCCCAAATC


 


901
CAAATTTCCG GAGGCAGCAA AAAAACCGTC CGCGCAGGCT TCCTCAAAGA


 


951
AGCCTACATC ACTCTGCCAC ATAAGGAAGC GAAAATGGCA GAACAAATTC


 


1001
TAGAAACCAT ACAGCCGATT CCCGCCCCAG TAAAAAAAGG GCAAATTTTA


 


1051
GGAAAAATCA AAATCAGACA AAACGGATAC ACCATTGCCG AAAAAGAAAT


 


1101
CGTCGCACTG GAAAATGTAA AAAAAAGAAG CCGGTGGCAA AGGCTTTGGG


 


1151
CGTGTCTGAC AGGGCAGTAA






This corresponds to the amino acid sequence <SEQ ID 1628; ORF 554>:










m554.pep..




1
MTAHKILPVL LSIILGVSHA TAASPAPNRP TVHAAPTFQT PETLTAAHIV


 


51
IDLQSKQILS AKNINTPVEP AALTQLMTAY LVFKNMKSGN IQSEENLKIP


 


101
ESAWASEGSR MFVRPGDTVS TDKLLKGMIA LSANDAALTL AGRLGNGSIE


 


151
NFVQQMNKEA RRLGMKNTVF KNPTGLSREG QVSTAKDLAL LSEALMRDFP


 


201
EYYPLFSIKS FKFKNIEQNN RNILLYRDNN VNGLKAGHTE SGGYNLAVSY


 


251
SGNGRHILVI TLGSESAETR ASDNSKLLNW ALQAFDTPKI YPKGKTVAQI


 


301
QISGGSKKTV RAGFLKEAYI TLPHKEAKMA EQILETIQPI PAPVKKGQIL


 


351
GKIKIRQNGY TIAEKEIVAL ENVKKRSRWQ RLWACLTGQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 554 shows 96.1% identity over a 389 aa overlap with a predicted ORF (ORF 554.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1629>:










a554.seq




1
ATGACAGCAC ATAAAATCCT GCCCGTCCTG CTTTCCATCA TCTTAGGCGT


 


51
TTCTCACGCA ACGGCTGCAT CGCCCGCGCC CAACAGACCG ACGGCACACG


 


101
CCGCCCCCAC GTTCCAAACA CCCGAAACCC TCACAGCGGC ACACATCGTT


 


151
ATCGACCTTC AAAGCAAACA GATTTTATCC GCCAAAAACA TCAATACCCC


 


201
TGTCGAACCG GCGGCACTAA CCCAACTGAT GACCGCATAT CTGGTTTTCA


 


251
AAAACATGAA ATCGGGAAAT ATCCGATCTG AAGAAAACTT AAAAATACCC


 


301
GAATCCGCAT GGGCTTCAGA AGGAAGCAGA ATGTTTGTAC GTCCCGGCGA


 


351
TACGGTCAGC ACCGACAAAC TCTTAAAAGG CATGATTGCA CTATCCGCAA


 


401
ACGATGCCGC CCTAACCCTT GCCGGCCGGC TGGGCAACGG CTCGATTGAA


 


451
AATTTTGTGC AACAAATGAA CAAAGAAGCC CGACGCTTGG GCATGAAGAA


 


501
CACTGTATTC AAAAATCCGA CAGGCTTGAG TAGAGAAGGA CAGGTTTCCA


 


551
CCGCCAAAGA CCTCGCCCAG CTGTCTGAAG CATTGATGCG CGACTTTCCG


 


601
GAATATTACC CGCTGTTTTC CATCAAATCT TTCAAATTCA AAAATATAGA


 


651
GCAAAACAAC CGCAATATCC TTTTATATAG GGACAACAAT GTAAACGGTC


 


701
TGAAAGCCGG ACACACAGAA AGCGGCGGCT ACAACCTTGC CGTGTCATAC


 


751
TCCGGCAACG GCAGGCACAT CCTTGTCATC ACATTGGGTT CGGAATCGGC


 


801
GGAAACACGC GCATCAGACA ACAGCAAGCT GCTGAACTGG GCATTGCAAG


 


851
CCTTCGATAC GCCCAAAATA TATCCGAAAG GCAAAACCGT TGCCCAAATC


 


901
CAAATTTCCG GAGGCAGCAA AAAAACCGTC CGCGCAGGCT TCCTCAAAGA


 


951
AGCCTACATC ACTCTGCCAC ATAAGGAAGC GAAAATGGCA GAACAAATTC


 


1001
TAGAAACCAT ACAGCCGATT CCCGCCCCAG TAAAAAAAGG GCAAATTTTA


 


1051
GGAAAAATCA AAATCAGACA AAACGGATAC ACCATTGCCG AAAAAGAAAT


 


1101
CGTCGCACTG GAAAATGTAA AAAAAAGAAG CCGGTGGCAA AGGCTTTGGG


 


1151
CGTGTCTGAC AGGGCAGTAA






This corresponds to the amino acid sequence <SEQ ID 1630; ORF 554.a>:










a554.pep




1
MTAHKILPVL LSIILGVSHA TAASPAPNRP TAHAAPTFQT PETLTAAHIV


 


51
IDLQSKQILS AKNINTPVEP AALTQLMTAY LVFKNMKSGN IRSEENLKIP


 


101
ESAWASEGSR MFVRPGDTVS TDKLLKGMIA LSANDAALTL AGRLGNGSIE


 


151
NFVQQMNKEA RRLGMKNTVF KNPTGLSREG QVSTAKDLAQ LSEALMRDFP


 


201
EYYPLFSIKS FKFKNIEQNN RNILLYRDNN VNGLKAGHTE SGGYNLAVSY


 


251
SGNGRHILVI TLGSESAETR ASDNSKLLNW ALQAFDTPKI YPKGKTVAQI


 


301
QISGGSKKTV RAGFLKEAYI TLPHKEAKMA EQILETIQPI PAPVKKGQIL


 


351
GKIKIRQNGY TIAEKEIVAL ENVKKRSRWQ RLWACLTGQ*






m554/a554 99.2% identity in 389 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1631>:










g556.seq..




1
atggacaata agaccaaact gcgcttgggc ggcctgattt tactgaccac


 


51
cgccgtttta agcctcatta tcgtattgat tgtcgattcc tggccgcttg


 


101
ccatcctgct tgccgccgtc atcgtcgccg ccgctgcggg cggctttgtt


 


151
tggacatccc gccgacagca acgccagttt atcgaacgtc tgaaaaaatt


 


201
cgacatcgat cccgaaaaag gcagaatcaa cgaggcaaac ctgcgccgta


 


251
tgtaccacag cggcggacaa caccagaaag atgcgattac cctgatctgc


 


301
ctgtcgcaaa aatgttcggt ggacgaggcg cacgctatgt tcaaaaaacg


 


351
cccgacacgt caggaaatca atcaaatggc ggcaaaacag tcgcgcggtc


 


401
agaaacgtcc gcaccgttaa






This corresponds to the amino acid sequence <SEQ ID 1632; ORF 556.ng>:










g556.pep.




1
MDNKTKLRLG GLILLTTAVL SLIIVLIVDS WPLAILLAAV IVAAAAGGFV


 


51
WTSRRQQRQF IERLKKFDID PEKGRINEAN LRRMYHSGGQ HQKDAITLIC


 


101
LSQKCSVDEA HAMFKKRPTR QEINQMAAKQ SRGQKRPHR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1633>:










m556.seq..




1
ATGGACAATA AGACCAAACT GCGCTTGGGC GGCCTGATTT TACTGACCAC


 


51
CGCCGTTTTA AGCCTCATTA TCGTATTGAT TGTCGATTCC TGGCCGCTTG


 


101
CCATCCTGCT TGCAGCCGTC ATTGTCGCTG CCGCTGCGGG CGGTTTTGTT


 


151
TGGACATCCC GCCGACAGCA ACGCCAGTTT ATCGAACGCC TGAAAAAATT


 


201
CGACATCGAT CCCGAAAAAG GCAGAATCAA CGAGGCAAAC CTGCGCCGTA


 


251
TGTACCACAG CGGCGGACAA CACCAGAAAG ATGCGATTAC CCTGATCTGC


 


301
CTGTCGCAAA AATGTTCGGT GGACGAGGCG CACGCTATGT TCAAAAAACG


 


351
CCCGACACGT CAGGAAATCA ATCAAATGGC GGCAAAACAG TCGCGCGGTC


 


401
AGAAACGTCC GCACCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1634; ORF 556>:










m556.pep..




1
MDNKTKLRLG GLILLTTAVL SLIIVLIVDS WPLAILLAAV IVAAAAGGFV


 


51
WTSRRQQRQF IERLKKFDID PEKGRINEAN LRRMYHSGGQ HQKDAITLIC


 


101
LSQKCSVDEA HAMFKKRPTR QEINQMAAKQ SRGQKRPHR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 556 shows 100.0% identity over a 139 aa overlap with a predicted ORF (ORF 556.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1635>:










a556.seq




1
ATGGACAATA AGACCAAACT GCGCTTGGGC GGCCTGATTT TACTGACCAC


 


51
CGCCGTTTTA AGCCTCATTA TCGTATTGAT TGTCGATTCC TGGCCGCTTG


 


101
CCATCCTGCT TGCCGCCGTC ATCGTCGCCG CCGCTGCGGG CGGCTTTGTT


 


151
TGGACATCCC GCCGACAGCA ACGCCAGTTT ATCGAACGTC TGAAAAAATT


 


201
CGACATCGAT CCCGAAAAAG GCAGAATCAA CGAGGCAAAC CTGCGCCGTA


 


251
TGTACCACAG CGGCGGACAA CACCAAAAAG ATGCGATTAC CCTGATCTGC


 


301
CTGTCGCAAA AATGTTCGGT GGACGAGGCG CACGCTATGT TCAAAAAACG


 


351
CCCGACACGT CAGGAAATCA ATCAAATGGC GGCAAAACAG TCGCGCGGTC


 


401
AGAAACGTCC GCACCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1636; ORF 556.a>:










a556.pep




1
MDNKTKLRLG GLILLTTAVL SLIIVLIVDS WPLAILLAAV IVAAAAGGFV


 


51
WTSRRQQRQF IERLKKFDID PEKGRINEAN LRRMYHSGGQ HQKDAITLIC


 


101
LSQKCSVDEA HAMFKKRPTR QEINQMAAKQ SRGQKRPHR*






m556/a556 100.0% identity in 139 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1637>:










g557.seq




1
atgaacaaaa tattccttac tgccgcagcc ttggtgctgg gcgcgtgcgg


 


51
tttccacctg aaaggtgcag acggcatttc tccgccgctg acctaccgga


 


101
gctggcacat cgaaggcgga caggcattgc aatttccttt ggaaaccgcg


 


151
ctgtatcagg cttcgggcag ggtggacgat gctgccggcg cgcagatgac


 


201
cctgcgtata gacagcgttt cccaaaacaa ggaaacctat accgttaccc


 


251
gtgcggcagt catcaacgaa tatcttttga tattgacggt tgaagcgcag


 


301
gtattgaaac gcggcgagcc ggtcggcaaa ccgatgaccg tgtccgtccg


 


351
ccgcattttg gattatgccg acaacgaaat tttgggcaaa caggaagaag


 


401
aagaaaccct gtgggcggaa atgcggcagg atgttgccga acagattgtc


 


451
cgccgcctga cctttctgaa ggcggaatga






This corresponds to the amino acid sequence <SEQ ID 1638; ORF 557.ng>:










g557.pep..




1
MNKIFLTAAA LVLGACGFHL KGADGISPPL TYRSWHIEGG QALQFPLETA


 


51
LYQASGRVDD AAGAQMTLRI DSVSQNKETY TVTRAAVINE YLLILTVEAQ


 


101
VLKRGEPVGK PMTVSVRRIL DYADNEILGK QEEEETLWAE MRQDVAEQIV


 


151
RRLTFLKAE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1639>:










m557.seq..




1
ATGAACAAAC TGTTTCTTAC TGCCGCAGTG CTGATGCTGG GCGCGTGCGG


 


51
TTTCCACCTG AAAGGTGCAG ACGGCATTTC TCCGCCGCTG ACCTACCGGA


 


101
GCTGGCACAT CGAAGGCGGA CAGGCATTGC GGTTTCCTTT GGAAACCGCG


 


151
CTGTATCAGG CTTCGGGCAG GGTGGACGAT GCTGCCGGCG CGCAGATGAC


 


201
CCTGCGTATA GACAGCGTTT CCCAAAACAA GGAAACCTAC ACCGTTACCC


 


251
GTGCGGCAGT CATCAACGAA TATCTTTTGA TATTGACGGT TGAAGCGCAG


 


301
GTATTGAAAC GCGGCGAGCC GGTCGGTAAA CCGATGACCG TGTCCGTCCG


 


351
CCGCGTCCTT GCTTATGCCG ACAACGAGAT CTTGGGCAAA CAGGAAGAGG


 


401
AAGCGGCATT GTGGGCGGAA ATGCGGCAGG ATGCCGCCGA ACAGATTGTC


 


451
CGCCGCCTGA CCTTTCTGAA GGCGGAATGA






This corresponds to the amino acid sequence <SEQ ID 1640; ORF 557>:










m557.pep..




1
MNKLFLTAAV LMLGACGFHL KGADGISPPL TYRSWHIEGG QALRFPLETA


 


51
LYQASGRVDD AAGAQMTLRI DSVSQNKETY TVTRAAVINE YLLILTVEAQ


 


101
VLKRGEPVGK PMTVSVRRVL AYADNEILGK QEEEAALWAE MRQDAAEQIV


 


151
RRLTFLKAE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 557 shows 94.3% identity over a 159 aa overlap with a predicted ORF (ORF 557.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1641>:










a557.seq




1
ATGAACAAAC TGTTTCTTAC TGCCGCAGTG CTGATGCTGG GCGCGTGCGG


 


51
TTTCCACCTG AAAGGTGCAG ACGGCATTTC TCCGCCGCTG ACCTACCGGA


 


101
GCTGGCACAT CGAAGGCGGA CAGGCATTGC AGTTTCCTTT GGAAACCGCG


 


151
CTGTATCAGG CTTCGGGTAG GGTGGACGAT GCTGCCGGCG CGCAGATGAC


 


201
CCTGCGTATA GACAGCGTTT CCCAAAACAA GGAAACCTAC ACCGTTACCC


 


251
GTGCGGCAGT CATCAACGAA TATCTTTTGA TATTGACGGT TGAAGCGCAG


 


301
GTATTGAAAC GCGGCGAGCC GGTCGGCAAA CCGATGACCG TGTCCGTCCG


 


351
CCGCGTCCTT GCTTATGCCG ACAACGAGAT CTTGGGCAAA CAGGAAGAGG


 


401
AAGCGGCATT GTGGGCGGAA ATGCGGCAGG ATGCCGCCGA ACAGATTGTC


 


451
CGCCGCCTGA CCTTTCTGAA GGCGGAATGA






This corresponds to the amino acid sequence <SEQ ID 1642; ORF 557.a>:










a557.pep




1
MNKLFLTAAV LMLGACGFHL KGADGISPPL TYRSWHIEGG QALQFPLETA


 


51
LYQASGRVDD AAGAQMTLRI DSVSQNKETY TVTRAAVINE YLLILTVEAQ


 


101
VLKRGEPVGK PMTVSVRRVL AYADNEILGK QEEEAALWAE MRQDAAEQIV


 


151
RRLTFLKAE*






m557/a557 99.4% identity in 159 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1643>:










g558.seq..




1
ATGGATGCTT GTTTTTTCGT CATTCCCGCA CAGGCGGGAA TTCGGAGATT


 


51
CGGGATTGTT TTCAAACGTT CGGGTCGGAT TCTTGCCGGT GCGGGAATGA


 


101
TGCCCTTATA TACTTTCTCC GAGCTTTATA TGCTTCAACA GGGGACGGCA


 


151
CATCAAGCAC CGCACTGCGT GTTGCCCGAA CGAGGCTGCC CTCCGATTAG


 


201
ATTCTATCGC TATAAACAGA CGGGTTTCAA CCGAAAAGGA ATGGGGATAA


 


251
AGTCCATTTC CGACACCTCT CGGGCGATGC CGTCTGAAAA CCAATCTCCA


 


301
CTTTCAGACG GCATTGTTTA G






This corresponds to the amino acid sequence <SEQ ID 1644; ORF 558.ng>:










g558.pep..




1
MDACFFVIPA QAGIRRFGIV FKRSGRILAG AGMMPLYTFS ELYMLQQGTA


 


51
HQAPHCVLPE RGCPPIRFYR YKQTGFNRKG MGIKSISDTS RAMPSENQSP


 


101
LSDGIV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1645>:










m558.seq..




1
ATGAATGCTT GTTTTTTCGT CATTCCCACA CAGGCGGGAA TTCGGAGATT


 


51
CGGGATTGTT TTCAAACGTT CGGGTCGGAT TCTTGCCGGT GCAGGAATGA


 


101
TGCCCTTATA TACTTTCTCC GAGCTTTATA TGTTTCAACA GGGGACGGCA


 


151
CATCAAGCAC CGCACTGCGT GTTGCCCGAA CGAGACTACC CTCCGATTAG


 


201
ATTCTATCGC CATAAACAGA CGGGTTTCAA CCGAAAAGGA ATGGGGATAA


 


251
AGTCCATTTC CGACATCTsT CGGGCGATGC CGTCTGAAAA CCAATCTCCA


 


301
CTTTCAGACG GCATTGTTTA G






This corresponds to the amino acid sequence <SEQ ID 1646; ORF 558>:










m558.pep..




1
MNACFFVIPT QAGIRRFGIV FKRSGRILAG AGMMPLYTFS ELYMFQQGTA


 


51
HQAPHCVLPE RDYPPIRFYR HKQTGFNRKG MGIKSISDIX RAMPSENQSP


 


101
LSDGIV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 558 shows 92.5% identity over a 106 aa overlap with a predicted ORF (ORF 558.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1647>:










a558.seq




1
ATGAATGCTT GTTTTTTCGT CATTCCCACA CAGGCGGGAA TTCGGAGATT


 


51
CGGGATTGTT TTCAAACGTT CGGGTCGGAT TCTTGCCGGT GCGGGAATGA


 


101
TGCCCTTATA TATAGTGGAT TAAATTTAAA TCAGGACAAG GCGACGAAGC


 


151
CGCAGACAGT ACAAATAGTA CGGCAAGGCG AGGCAACGCC GTACTGGTTT


 


201
AAATTTAATC CACTATACTT TCTCCGAGCT TTATATGTTT CAACAGAGGA


 


251
CGGCACATCA AGCACCGCAC TGCGTGTTGC CCGAACGAGA CTGCCCTCCG


 


301
ATTAGATTCT ATCGCTATAA ACAGACGGGT TTCAACCGAA AAGGAATGGG


 


351
AATGAAGTCC GTTTCCGACA CCTCTCGGGC GATGCCGTCT GAAAACCAAT


 


401
CTCCACTTTC AGACGGCATT GTTTAG






This corresponds to the amino acid sequence <SEQ ID 1648; ORF 558.a>:










a558.pep




1
MNACFFVIPT QAGIRRFGIV FKRSGRILAG AGMMPLYIVD *I*IRTRRRS


 


51
RRQYK*YGKA RQRRTGLNLI HYTFSELYMF QQRTAHQAPH CVLPERDCPP


 


101
IRFYRYKQTG FNRKGMGMKS VSDTSRAMPS ENQSPLSDGI V*






m558/a558 70.2% identity in 141 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1649>:










g560.seq




1
atgctcatca tccgcaacct gatttactgg ctgatactct gttccagcct


 


51
gattttcctc tttcccttta tgctgctcgc ctcgcctttc cgggacgggg


 


101
cgcacaagat ggcgcgggtc tgggtcggca tcctcaactg gtcgctcaaa


 


151
cacatcgtcg ggctcaaata ccgcatcatc ggcgcggaac acattccgga


 


201
ccgcccctcc gtcatctgcg ccaaacacca aagcggctgg gaaacgctcg


 


251
cgctccaaga gatttttccg ccgcaggttt acgttgccaa gcgcgagttg


 


301
ttcaaaatcc cctttttcgg ctggggcttg aaactggtca aaaccatagg


 


351
catagaccgc aacaaccgcc gcgaagccaa cgaacagctc ataaaacagg


 


401
gtttggcgcg caaaaacgaa ggttattgga ttaccatttt ccccgaaggc


 


451
acgcgccttg cgcccggaaa acgcggcaaa tacaaactcg gcggcgcgcg


 


501
catggcgaaa atgtttgaga tggacatcgt ccccgtcgcc ctcaacagcg


 


551
gcgaattttg gccgaaaaat tcctttctga aatatccggg ggaaatcacc


 


601
gtcatcatct gtccgaccat cccgcacgca agcggcagcg aagccgaatt


 


651
gatggaaaaa tgcgaacacc tcattgaaac gcaacaaccg cttatttccg


 


701
gcgcaggccc gtttgccgcc gaaatgccgt ctgaaaccgc atga






This corresponds to the amino acid sequence <SEQ ID 1650; ORF 560.ng>:










g560.pep..




1
MLIIRNLIYW LILCSSLIFL FPFMLLASPF RDGAHKMARV WVGILNWSLK


 


51
HIVGLKYRII GAEHIPDRPS VICAKHQSGW ETLALQEIFP PQVYVAKREL


 


101
FKIPFFGWGL KLVKTIGIDR NNRREANEQL IKQGLARKNE GYWITIFPEG


 


151
TRLAPGKRGK YKLGGARMAK MFEMDIVPVA LNSGEFWPKN SFLKYPGEIT


 


201
VIICPTIPHA SGSEAELMEK CEHLIETQQP LISGAGPFAA EMPSET*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1651>:










m560.seq




1
ATGCTCATCA TCCGCAACCT GATTTACTGG CTGATACTCT GTTCCACCCT


 


51
GATTTTCCTC TTTCCCTTTA TGCTGCTCGC CTCGCCTTTC CGGGACGGGG


 


101
CGCACAAGAT GGCGCGGGTC TGGGTCGGCA TTCTCAACTG GTCGCTCAAA


 


151
CACATCGTCG GGCTCAAATA CCGCATCATC GGCGCGGAAA ACATCCCCGA


 


201
CCGCCCCGCC GTCATCTGCG CCAAACACCA AAGCGGCTGG GAAACGCTCG


 


251
CCCTTCAGGA CATTTTTCCG CCGCAGGTTT ACGTTGCCAA ACGCGAGTTG


 


301
TTCAAAATCC CCTTTTTCGG CTGGGGCTTG AAACTGGTCA AAACCATAGG


 


351
CATAGACCGC AACAACCGCC GCGAAGCCAA CGAGCAGCTC ATAAAACAGG


 


401
GGTTGGTGCG CAAAAACGAA GGCTATTGGA TTACCATTTT CCCCGAAGGC


 


451
ACGCGCCTTG CGCCCGGAAA ACGCGGCAAA TACAAACTCG GCGGCGCGCG


 


501
CATGGCGAAA ATGTTTGAGA TGGACATCGT CCCCGTCGCC CTCAACAGCG


 


551
GCGAATTTTG GCCGAAAAAC TCCTTTCTGA AATATCCGGG GGAAATCACC


 


601
GTCGTCATCT GTCCGACCAT CCCGCACGCA AGCGGCAGCG AAGCCGAATT


 


651
GATGGAAAAA TGCGAACATC TCATCGAAAC GCAACAACCG CTTATTTCCG


 


701
GCGCAGGCCC GTTTGCCGCC AAAATGCCGT CTGAAACCGC ATGA






This corresponds to the amino acid sequence <SEQ ID 1652; ORF 560>:










m560.pep




1
MLIIRNLIYW LILCSTLIFL FPFMLLASPF RDGAHKMARV WVGILNWSLK


 


51
HIVGLKYRII GAENIPDRPA VICAKHQSGW ETLALQDIFP PQVYVAKREL


 


101
FKIPFFGWGL KLVKTIGIDR NNRREANEQL IKQGLVRKNE GYWITIFPEG


 


151
TRLAPGKRGK YKLGGARMAK MFEMDIVPVA LNSGEFWPKN SFLKYPGEIT


 


201
VVICPTIPHA SGSEAELMEK CEHLIETQQP LISGAGPFAA KMPSETA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 560 shows 97.2% identity over a 246 aa overlap with a predicted ORF (ORF 560.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1653>:










a560.seq




1
ATGCTCATCA TCCGCAACCT GATTTACTGG CTGATACTCT GTTCCACCCT


 


51
GATTTTCCTC TTTCCCTTTA TGCTGCTCGC CTCGCCTTTC CGAGACGGGG


 


101
CGCACAAGAT GGCGCGGGTC TGGGTCAAAA TCCTCAACCT CTCGCTCAAA


 


151
CACATCGTCG GGCTCAAATA CCGCATCATC GGCGCGGAAA ACATCCCCGA


 


201
CCGCCCCGCC GTCATCTGCG CCAAACACCA AAGCGGCTGG GAAACGCTCG


 


251
CCCTTCAGGA CATTTTTCCG CCGCAGGTTT ACGTTGCCAA ACGCGAGTTG


 


301
TTCAAAATCC CCTTTTTCGG CTGGGGCTTG AAACTGGTCA AAACCATAGG


 


351
CATAGACCGC AACAACCGCC GCGAAGCCAA CGAGCAGCTC ATAAAACAGG


 


401
GGTTGGCGCG CAAAAACGAA GGCTATTGGA TTACCATTTT CCCCGAAGGC


 


451
ACACGCCTTG CGCCCGGAAA ACGCGGCAAA TACAAACTCG GCGGCGCGCG


 


501
CATGGCGAAA ATGTTTGAGA TGGACATCGT CCCCGTCGCC CTCAACAGCG


 


551
GCGAATTTTG GCCGAAAAAC TCCTTTCTGA AATATCCGGG GGAAATCACC


 


601
GTCGTCATCT GTCCGACCAT CCCGCACGCA AGCGGCAGCG AAGCCGAATT


 


651
GATGGGAAAA TGCGAACACC TCATCGAAAC GCAGCAGCCG CTCATTTCCG


 


701
GCGCAGGCCC GTTTGCCGCC AAAATGCCGT CTGAAACCGC ATGA






This corresponds to the amino acid sequence <SEQ ID 1654; ORF 560.a>:










a560.pep




1
MLIIRNLIYW LILCSTLIFL FPFMLLASPF RDGAHKMARV WVKILNLSLK


 


51
HIVGLKYRII GAENIPDRPA VICAKHQSGW ETLALQDIFP PQVYVAKREL


 


101
FKIPFFGWGL KLVKTIGIDR NNRREANEQL IKQGLARKNE GYWITIFPEG


 


151
TRLAPGKRGK YKLGGARMAK MFEMDIVPVA LNSGEFWPKN SFLKYPGEIT


 


201
VVICPTIPHA SGSEAELMGK CEHLIETQQP LISGAGPFAA KMPSETA*






m560/a560 98.4% identity in 247 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1655>:










m561.seq.




1
ATGATACTGC CAGCCCGTTT TTCAGACGGC ATCAGCCTTT CCCTGCGCCT


 


51
GAAACTCCTG ACCGGACTGT GGGTCGGGTT GGCGGCATTG TCTGTCGTTT


 


101
TGACACTGCT GCTCTCTTTG CGTCTGGAAA ACGCGGCCTC CGTCATCGAA


 


151
GAGGCGGGCA ACTTGAGAAT GCAGGCATAC CGTCTGGCAT ACATGGCGGG


 


201
TGAAGGCTCG CCCCGTGCGC AAATTGACAA TCAGGTTGCC GAATTTGAAA


 


251
AAAGTTTAAA ACGCATTGCC CAAAGCGATG CCATCCATCC GCTGATTCCT


 


301
TCGGACACCC CTCTTGCTTA TGATTTGATA CAATCCATGC TGATTATAGA


 


351
TTGGCAGGCA CACATCCTCC CCCCGCTCCA GTCCTACCGG CGACCGACTC


 


401
AGGTCGATCT CTACCGCTTT GCCGGAAACA TCGAACTGTT TTTGCAGGCA


 


451
TTGGAAAATG CCAACGAAAA AAACACATGG TGGCTCAGGC GTTTTCAATG


 


501
GGCAATTATG TTGATGACGC TGGTGTCGTC TGTACTGATG CTGTTTTGGC


 


551
ACCAGATTTG GGTTATCCGG CCGCTGCAGG CGTTAAGGGA AGGTGCGGAA


 


601
CGCATCGGAC GGAGGTGTTT CGATATTCCG GTTCCCGAAG GCGGTACGCC


 


651
GGAATTCAAA CAGGTCGGGC GTTGTTTCAA TCAAATGGGC GGCAGGTTGA


 


701
AAATTTTATA TGATGATTTG GAAGGACAAG TCGCCGAGCA GACACGCAGT


 


751
CTCGAAAAAC AAAATCAAAA CCTGACCCTG CTGTACCAAA CTACACGGGA


 


801
CCTGCACCAA TCCTACATAC CGCAACAGGC TGCAGAACAT TTTCTAAACC


 


851
GTATCCTGCC CGCCGTAGGA GCAGATTCCG GCAGAGTTTG TTTGGACGGC


 


901
GGATCCGATG TTTATGTTTC CATTCATCAT GCGGATTGCG GCACAGCAGC


 


951
TTCGGATTTG GGGAAGTACC ATGAGGAAAT CTTCCCCATT GAGTACCAGA


 


1001
ACGAAACATT GGGCAGGCTG TTGCTCAGCT TTCCAAACGG CATTTCTCTT


 


1051
GATGAAGACG ACCGCATCCT GCTTCAAACA CTAGGCAGGC AATTGGGCGT


 


1101
ATCGCTTGCC GGCGCAAAAC AGGAGGAAGA AAAACGCCTG CTTGCAGTAT


 


1151
TGCAGGAACG CAACCTGATT GCGCAAGGAT TACATGACAG CATCGCACAA


 


1201
GCATTAACGT TCCTAAACCT ACAGGTACAG ATGCTGGAAA CCGCCTTTGC


 


1251
CGAAAACAAA CGGGAGGAAG CCGCAGAAAA CATCAGCTTT ATCAAAACAG


 


1301
GCGTGCAGGA ATGTTATGAA GATGTCCGCG AACTGCTGCT CAACTTCCGT


 


1351
ACCAAAATCA GCAATAAAGA ATTTCCCGAA GCCGTTGCCG ACCTATTCGC


 


1401
CCGCTTTACG CAACAAACCG GGATAACGGT CGAAACCGCC TGGGAAAACG


 


1451
GTTCGTTCCT GCCGCCTCAG GAAGCGCAGC TCCAAATGAT TTTTATCCTG


 


1501
CAGGAAAGCC TGTCCAACAT CCGCAAACAC GCCCGCGCCA CCCATGTAAA


 


1551
ATTCACCCTT TCCGAACACG GCGGACGCTT TACCATGACC ATCCAAGACA


 


1601
ACGGACAAGG TTTCGACACG GAGAAAATAG GAGAACCCAC GGGCAGCCAT


 


1651
GTCGGACTGC ACATCATGCA GGAGCGTGCC AAACGCATCC ATGCCGTTTT


 


1701
AGAAATCCGT TCCCAAGCTC AACAGGGAAC CACCGTCTCA TTGACGGTTG


 


1751
CATCTGAAGA AAGCTTGAAA TGA






This corresponds to the amino acid sequence <SEQ ID 1656; ORF 561>:










m561.pep




1
MILPARFSDG ISLSLRLKLL TGLWVGLAAL SVVLTLLLSL RLENAASVIE


 


51
EAGNLRMQAY RLAYMAGEGS PRAQIDNQVA EFEKSLKRIA QSDAIHPLIP


 


101
SDTPLAYDLI QSMLIIDWQA HILPPLQSYR RPTQVDLYRF AGNIELFLQA


 


151
LENANEKNTW WLRRFQWAIM LMTLVSSVLM LFWHQIWVIR PLQALREGAE


 


201
RIGRRCFDIP VPEGGTPEFK QVGRCFNQMG GRLKILYDDL EGQVAEQTRS


 


251
LEKQNQNLTL LYQTTRDLHQ SYIPQQAAEH FLNRILPAVG ADSGRVCLDG


 


301
GSDVYVSIHH ADCGTAASDL GKYHEEIFPI EYQNETLGRL LLSFPNGISL


 


351
DEDDRILLQT LGRQLGVSLA GAKQEEEKRL LAVLQERNLI AQGLHDSIAQ


 


401
ALTFLNLQVQ MLETAFAENK REEAAENISF IKTGVQECYE DVRELLLNFR


 


451
TKISNKEFPE AVADLFARFT QQTGITVETA WENGSFLPPQ EAQLQMIFIL


 


501
QESLSNIRKH ARATHVKFTL SEHGGRFTMT IQDNGQGFDT EKIGEPTGSH


 


551
VGLHIMQERA KRIHAVLEIR SQAQQGTTVS LTVASEESLK *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m561/g561 89.7% identity in 223 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1657>:










a561.seq




1
ATGATACTGC CAGCCCGTTT TTCAGACGGC ATCAGCCTTT CCCTGCGCCT


 


51
GAAACTCCTG ACCGGACTGT GGGTCGGGTT GGCGGCATTG TCTGTCGTTT


 


101
TGACACTGCT GCTCTCTTTG CGTCTGGAAA ACGCGGCCTC CGTCATCGAA


 


151
GAGGCGGGCA ACTTGAGAAT GCAGGCATAC CGTCTGGCAT ACATGGCGGG


 


201
TGAAGGCTCG CCCCGTGCGC AAATTGACAA TCAGGTTGCC GAATTTGAAA


 


251
AAAGTTTAAA ACGCATTGCC CAAAGCGATG CCATCCATCC GCTGATTCCT


 


301
TCGGACACCC CTCTTGCTTA TGATTTGATA CAATCCATGC TGATTATAGA


 


351
TTGGCAGGCA CACATCCTCC CCCCGCTCCA GTCCTACCGG CGACCGACTC


 


401
AGGTCGATCT CTACCGCTTT GCCGGAAACA TCGAACTGTT TTTGCAGGCA


 


451
TTGGAAAATG CCAACGAAAA AAACACATGG TGGCTCAGGC GTTTTCAATG


 


501
GGCAATTATG TTGATGACGC TGGTGTCGTC TGTACTGATG CTGTTTTGGC


 


551
ACCAGATTTG GGTTATCCGG CCGCTGCAGG CGTTAAGGGA AGGTGCGGAA


 


601
CGCATCGGAC GGAGGTGTTT CGATATTCCG GTTCCCGAAG GCGGTACGCC


 


651
GGAATTCAAA CAGGTCGGGC GTTGTTTCAA TCAAATGGGC GGCAGGTTGA


 


701
AAATTTTATA TGATGATTTG GAAGGACAAG TCGCCGAGCA GACACGCAGT


 


751
CTCGAAAAAC AAAATCAAAA CCTGACCCTG CTGTACCAAA CTACACGGGA


 


801
TCTGCACCAA TCCTACATAC CGCAACAGGC TGCAGAACAT TTTCTAAACC


 


851
GTATCCTGCC CGCCGTAGGA GCAGATTCCG GCAGAGTTTG TTTGGACGGC


 


901
GGATCCGATG TTTATGTTTC CATTCATCAT GCGGATTGCG GCACAGCAGC


 


951
TTCGGATTTG GGGAAGTACC ATGAGGAAAT CTTCCCCATT GAGTACCAGA


 


1001
ACGAAACATT GGGCAGGCTG TTGCTCAGCT TTCCAAACGG CATTTCTCTT


 


1051
GATGAAGACG ACCGCATCCT GCTTCAAACA CTAGGCAGGC AATTGGGCGT


 


1101
ATCGCTTGCC GGCGCAAAAC AGGAGGAAGA AAAACGCCTG CTTGCAGTAT


 


1151
TGCAGGAACG CAACCTGATT GCGCAAGGAT TACATGACAG CATCGCACAA


 


1201
GCATTAACGT TCCTAAACCT ACAGGTACAG ATGCTGGAAA CCGCCTTTGC


 


1251
CGAAAACAAA CGGGAGGAAG CCGCAGAAAA CATCGGCTTC ATCAAAACAG


 


1301
GCGTGCAGGA ATGTTATGAA GATGTCCGCG AACTGCTGCT CAACTTCCGT


 


1351
ACCAAAATCA GTAATAAAGA ATTTCCCGAA GCCGTTGCCG ACCTATTCTC


 


1401
GCGCTTTACG CAACAGACCG GCACGACTGT CGAAACCGCT TGGGAAAACG


 


1451
GCACGCACCT GCCTACACAG GACGAGCAGC TCCAAATGAT TTTCATCCTG


 


1501
CAAGAAAGCT TGTCCAACAT CCGAAAACAT GCCCACGCCA CCCATATCAA


 


1551
ATTCAGACTG CTCAAACAGG ATGGAAGTTT TACAATGACC ATTCAAGACA


 


1601
ACGGACAGGG TTTTGACACG GAAAACATTG GAGAACCATC GGGCAGCCAT


 


1651
GTCGGACTGC ATATCATGCA GGAGCGTGCC AAACGCATCC ATGCCGTTTT


 


1701
AGAAATCCGT TCCCAAGCTC AACAGGGAAC CACCGTCTCA TTGACGGTTG


 


1751
CATCTGAAGA AAGCTTGAAA TGA






This corresponds to the amino acid sequence <SEQ ID 1658; ORF 561.a>:










a561.pep




1
MILPARFSDG ISLSLRLKLL TGLWVGLAAL SVVLTLLLSL RLENAASVIE


 


51
EAGNLRMQAY RLAYMAGEGS PRAQIDNQVA EFEKSLKRIA QSDAIHPLIP


 


101
SDTPLAYDLI QSMLIIDWQA HILPPLQSYR RPTQVDLYRF AGNIELFLQA


 


151
LENANEKNTW WLRRFQWAIM LMTLVSSVLM LFWHQIWVIR PLQALREGAE


 


201
RIGRRCFDIP VPEGGTPEFK QVGRCFNQMG GRLKILYDDL EGQVAEQTRS


 


251
LEKQNQNLTL LYQTTRDLHQ SYIPQQAAEH FLNRILPAVG ADSGRVCLDG


 


301
GSDVYVSIHH ADCGTAASDL GKYHEEIFPI EYQNETLGRL LLSFPNGISL


 


351
DEDDRILLQT LGRQLGVSLA GAKQEEEKRL LAVLQERNLI AQGLHDSIAQ


 


401
ALTFLNLQVQ MLETAFAENK REEAAENIGF IKTGVQECYE DVRELLLNFR


 


451
TKISNKEFPE AVADLFSRFT QQTGTTVETA WENGTHLPTQ DEQLQMIFIL


 


501
QESLSNIRKH AHATHIKFRL LKQDGSFTMT IQDNGQGFDT ENIGEPSGSH


 


551
VGLHIMQERA KRIHAVLEIR SQAQQGTTVS LTVASEESLK *






m561/a561 96.9% identity in 590 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1659>:










g562.seq..




1
atggcaagcc cgtcgagtct gcctttcaat tcgggcaaga ccaaaccgac


 


51
ggcttttgcc gcgccggttt tggtcggaat catgttttcc acgccgctgc


 


101
gggcgcggcg caggtctttg tggcgcacgt cggtaacggt ttggtcgttg


 


151
gtcagtgcgt ggatggtggt cattgcgcct ttgacgatgc cgacgctttc


 


201
gctcaacact ttggcaaccg gcgagaggca gttggtggtg caggaagcgt


 


251
tggaaacgac ggtcatgtcg gcggtcagga cgctgtcgtt cacgccgtac


 


301
acgacggttg catcgacatc gtcgccgccc ggtgcggaaa tgaggacttt


 


351
tttcgcgccg ctttcgaggt ggattttggc tttttctttg ctggtgaacg


 


401
cgccggtgca ttccatgacc aaatcgacac cgagttcttt ccacggcagt


 


451
tcggcagggt tgcgggtcga gaagaagggg attttgtcgc cgttgacgat


 


501
gaggttgccg ccgtcgtggg atacgtcggc ttcaaagcgt ccgtgtacgg


 


551
tgtcgaattt ggtcagatgg gcgttggttt caaggctgcc gctggcgttg


 


601
acggcgacga tttggagttg gtcttga






This corresponds to the amino acid sequence <SEQ ID 1660; ORF 562.ng>:










g562.pep




1
MASPSSLPFN SGKTKPTAFA APVLVGIMFS TPLRARRRSL WRTSVTVWSL


 


51
VSAWMVVIAP LTMPTLSLNT LATGERQLVV QEALETTVMS AVRTLSFTPY


 


101
TTVASTSSPP GAEMRTFFAP LSRWILAFSL LVNAPVHSMT KSTPSSFHGS


 


151
SAGLRVEKKG ILSPLTMRLP PSWDTSASKR PCTVSNLVRW ALVSRLPLAL


 


201
TATIWSWS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1661>:










m562.seq




1
ATGGCAAGCC CGTCGAGCCT GCCTTTCAAT TCGGGCAGTA CCAAACCGAC


 


51
GGCTTTTGCC GCGCCGGTTT TGGTCGGAAT CATGTTTTCC ACGCCGCTGC


 


101
GGGCGCGGCG CAGGTCTTTG TGGCGCACGT CGGTAACGGT TTGGTCGTTG


 


151
GTCAGCGCGT GGATGGTGGT CATCGCGCCT TTGACGATGC CGACGCTTTC


 


201
GCTCAACACT TTGGCAACCG GCGAGAGGCA GTTGGTGGTG CAGGAAGCGT


 


251
TGGAAACGAC GGTCATGTCG GCGGTCAGGA CGCTGTCGTT CACGCCGTAC


 


301
ACGACGGTTG CATCGACATC GTCGCCGCCC GGTGCGGAAA TGAGGACTTT


 


351
TTTCGCGCCG CTTTCGAGGT GGATTTTGGC TTTTTCTTTG CTGGTGAACG


 


401
CGCCGGTGCA TTCCATGACC AAATCGACAC CGAGTTCTTT CCACGGCAGT


 


451
TCGGCAGGGT TGCGGGTCGA GAAGAAGGGG ATTTTGTCGC CGTTGACGAT


 


501
GAGGTTGCCG CCGTCGTGGG ATACGTCGGC TTCAAAGCGT CCGTGCACGG


 


551
TGTCGAATTT GGTCAGATGG GCGTTGGTTT CAAGGCTGCC GCTGGCGTTG


 


601
ACGGCGACGA GTTGGAGTTG GTCTTGA






This corresponds to the amino acid sequence <SEQ ID 1662; ORF 562>:










m562.pep




1
MASPSSLPFN SGSTKPTAFA APVLVGIMFS TPLRARRRSL WRTSVTVWSL


 


51
VSAWMVVIAP LTMPTLSLNT LATGERQLVV QEALETTVMS AVRTLSFTPY


 


101
TTVASTSSPP GAEMRTFFAP LSRWILAFSL LVNAPVHSMT KSTPSSFHGS


 


151
SAGLRVEKKG ILSPLTMRLP PSWDTSASKR PCTVSNLVRW ALVSRLPLAL


 


201
TATSWSWS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m562/a562 99.0% identity in 208 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1663>:










a562.seq




1
ATGGCAAGCC CGTCGAGTTT GTCTTTCAAT TCGGGCAGTA CCAAACCGAC


 


51
GGCTTTTGCC GCGCCAGTTT TGGTCGGAAT CATGTTTTCC ACGCCGCTGC


 


101
GGGCGCGGCG CAGGTCTTTG TGGCGCACGT CGGTAACGGT TTGGTCGTTG


 


151
GTCAGCGCGT GGATGGTGGT CATCGCGCCT TTGACGATGC CGACGCTTTC


 


201
GCTCAACACT TTGGCAACCG GCGAGAGGCA GTTGGTGGTG CAGGAAGCGT


 


251
TGGAAACGAC GGTCATGTCG GCGGTCAGGA TGCTGTCGTT CACGCCGTAC


 


301
ACGACGGTTG CATCGACATC GTCGCCGCCC GGTGCGGAAA TGAGGACTTT


 


351
TTTCGCGCCG CTTTCCAGAT GAACTTTGGC TTTTTCTTTG CTGGTGAACG


 


401
CGCCGGTGCA TTCCATGACC AAATCGACAC CGAGTTCTTT CCACGGCAGT


 


451
TCGGCAGGGT TGCGGGTCNA GAAGAANGGG ATTTTGTCGC CGTTGACGAT


 


501
GAGGTTGCCG CCGTCGTGGG ATACGTCGGC TTCAAAGCGT CCGTGCACGG


 


551
TGTCGAATTT GGTGAGGTGG GCGTTGGTTT CAAGGCTGCC GCTGGCGTTG


 


601
ACGGCGACGA TTTGGAGTTG GTCTTGA






This corresponds to the amino acid sequence <SEQ ID 1664; ORF 562.a>:










a562.pep




1
MASPSSLSFN SGSTKPTAFA APVLVGIMFS TPLRARRRSL WRTSVTVWSL


 


51
VSAWMVVIAP LTMPTLSLNT LATGERQLVV QEALETTVMS AVRMLSFTPY


 


101
TTVASTSSPP GAEMRTFFAP LSR*TLAFSL LVNAPVHSMT KSTPSSFHGS


 


151
SAGLRVXKXG ILSPLTMRLP PSWDTSASKR PCTVSNLVRW ALVSRLPLAL


 


201
TATIWSWS*






m562/a562 96.6% identity in 208 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1665>:










g563.seq




1
ATGAACAAAA CCCTCTATCG TGTGATTTTC AACCGCAAAC GCGGTGCTGT


 


51
GGTAGCTGTT GCCGAAACCA CCAAGCGCGA AGGTAAAAGC TGTGCCGATA


 


101
GTGGTTCGGG CAGCGTTTAT GTGAAATCCG TTTCTTTCAT TCCTACTCAT


 


151
TCCAAAGCCT TTTGTTTTTC TGCATTAGGC TTTTCTTTAT GTTTGGCTTT


 


201
GGGTACGGTC AATATTGCTT TTGCTGACGG CATTATTACT GATAAAGCTG


 


251
CTCCTAAAAC CCAACAAGCC ACGATTCTGC AAACAGGTAA CGGCATACCG


 


301
CAAGTCAATA TTCAAACCcc tACTTCGGCa ggGGTTTCTG TTAATCAATA


 


351
TGCCCAGTTT GATGTGGGTA ATcgcGGGGC GATTTTAAAC AACAGTCGCA


 


401
GCAACACCCA AACACAGCTA GGCGGTTGGA TTCAAGGCAA TCCTTGGTTG


 


451
ACAAGGGGCG AAGCACGTGT GGTTGTAAAC CAAATCAACA GCAGCCATCC


 


501
TTCACAACTG AATGGCTATA TTGAAGTGGG TGGACGACGT GCAGAAGTCG


 


551
TTATTGCCAA TCCGGCAGGG ATTGCAGTCA ATGGTGGTGG TTTTATCAAT


 


601
GCTTCCCGTG CCACTTTGAC GACAGGCCAA CCGCAATATC AAGCAGGAGA


 


651
CTTTAGCGGC TTTAAGATAA GGCAAGGCAA TGCTGTAATC GCCGGACACG


 


701
GTTTGGATGC CCGTGATACC GATTTCACAC GTATTCTTTT GTATGCCAAC


 


751
AAAATCACCT TGATCAGTAC GGCCGAACAA GCAGGCATTC GTAATCAAGG


 


801
GCAGTTGTTT GCTTCTTCCG GTAATGTGGC GATTGATGCA AATGGCCGTT


 


851
TGGTCAATAG TGGCACGATG GCTGCCGCCA ATGTGCAAGA TATGAATAAT


 


901
ACAGCGGAAC ACAAAGTCAA TATCCGCAGT CAAGCCTTTG AAAACAGCGG


 


951
TACGGCGGTA TCGCAACAAG GCACTCAAAT TCACAGTCAA TCGATTCAAA


 


1001
ACACTGGCAA ATTATTGTCG GCAGGAACAG AGGATTTAGC CGTTTCAGGC


 


1051
AGCCTGAACA ATCAAAATGG CGAAATAGCG ACCAATCAAC AACTGATTAT


 


1101
TCACGATGGT CAGCAATCTA CCGTTGTCAT TGATAATACG AATGGCACGA


 


1151
TACAATCAGG CCGTGATGTT GCCATTCAGG CAAAATCGTT ATCCAACAAC


 


1201
GGCACACTTG CCGCTGATAA TAAACTGGAT ATTGCGTTAC AAGATGATTT


 


1251
TTATGTAGAA CGCAAGATCG TGGCGGGCAA TGAATTGTCG CTCAGTACAC


 


1301
GAGGCAGCCT GAAAAATTCA CATACCTTGC AAGCAGGAAA ACGCATTCGG


 


1351
ATTAAAGCAA ATAACCTTGA TAATGCAGTA CAAGGCAACA TTCAATCCGG


 


1401
CGGTACGACA GACATTGGCA CGCAGCACAA TTTAACCAAT AGAGGCTTGA


 


1451
TTGACGGACA ACAAACCAAA ATCCAAGCCG GGCAAATGAA TAATATCGGT


 


1501
ACAGGTCGGA TTTATGGCGA CAATATCGCT ATTGCGGCTA CCCGCTTAGA


 


1551
CAATCAAGAT GAAAACGGTA CAGGTGCCGC CATTGCGGCA CGCGAAAACC


 


1601
TGAATTTAGG CATTGAACAA TTAAATAACC GTGAAAACAG TCTGATTTAC


 


1651
AGCGGTAACG ATATGGCGGT TGGCGGCGCA TTAGATACCA ATGACCAAGC


 


1701
CACAGGCAAA GCCCAAAGGA TACACAATGC CGGCGCAATC ATTGAAGCTG


 


1751
CAGGCAAAAT GCGTTTAGGT GTAGAAAAGC TGCACAATAC CAATGAGCAT


 


1801
TTGAAAACGC AGTTGGTAGA AACAGGGCGC GAGCGTATTG TTGATTACGA


 


1851
AGCATTTGGA CGACACGAAT TATTGCGAGA AGGCACGCAA CATGAATTAG


 


1901
GCTGGTTTGT CTACAACAAT GAATCAGACC ACTTACGCAC CCCTGATGGA


 


1951
GTGGCGCATG AAAATTGGCA TAAATACGAT TATGAAAAAG TAACGCAAGA


 


2001
AACTCAAGTA ACCGGAACTG CGCCTGCTAA AATCATTGCA GGTAGCGATT


 


2051
TGATTATTGA TAGCAAAGCA GTCTTCAACA GCGACAGCCG AATCATTGCC


 


2101
GGCGGCCAAT TGCTTGTGCA AACAGAAAAA GACGGTTTGC ATAACGAGCA


 


2151
AACCTTTGGC GAGAAGAAAG TCTTCAGCGA AAATGGTAAG TTGCACAACT


 


2201
ACTGGCGTGC GCGTCGTAAA GGACATGATG AAACAGGGCA TCGTGAACAA


 


2251
AATTATACTT TGCCGGAGGA AATCACACGC GACATTTCAC TGGGTTCATT


 


2301
TGCCTATGAA TCGCATAGCA AAGCATTAAG CCGTCATGCG CCCAGCCAAG


 


2351
GCACTGAGTT GCCACAAAGT AACCGGGATA ATATCCGTAC TGCGAAAAGC


 


2401
AACGGTATTT CGCTACCCTA TACGCCCAAT TCTTTTACCC CATTACCCGG


 


2451
CAGCAGCTTA TACATTATCA ATCCTGCCAA TAAAGGCTAT CTTGTTGAAA


 


2501
CCGATCCACG CTTTGCCAAC TACCGTCAAT GGTTGGGTAG TGACTATATG


 


2551
CTGGGCAGCC TCAAACTAGA CCCAAACAAT TTACATAAAC GTTTGGGTGA


 


2601
TGGTTATTAC GAGCAACGTT TAATCAATGA ACAAATCGCA GAGCTGACAG


 


2651
GGCATCGTCG TTTAGACGGT TATCAAAACG ACGAAGAACA ATTTAAAGCC


 


2701
TTAATGGATA ATGGCGCGAC TGCGGCACGT TCGATGAATC TCAGCGTTGG


 


2751
CATTGCATTA AGTGCCGAGC AAGCAGCGCA ACTGACCAGC GATATTGTTT


 


2801
GGTTGGTACA AAAAGAAGTT AAACTTCCTG ATGGCGGCAC ACAAACCGTA


 


2851
TTGATGCCAC AGGTTTATGT ACGCGTTAAA AATGGCGGCA TAGACGGTAA


 


2901
AGGTGCATTG TTGTCAGGCA GCAATACACA AATCAATGTT TCAGGCAGCC


 


2951
TGAAAAACTC AGGCACGATT GCAGGGCGCA ATGCGCTTAT TATCAATACC


 


3001
GATACGCTAG ACAATATCGG TGGGCGTATT CATGCGCAAA AATCAGCGGT


 


3051
TACGGCCACA CAAGACATCA ATAATATTGG CGGCATTCTT TCTGCCGAAC


 


3101
AGACATTATT GCTCAATGCG GGTAACAACA TCAACAACCA AAGCACGGCC


 


3151
AAGAGCAGTC AAAATGCACA AGGTAGCAGC ACCTACCTAG ACCGAATGGC


 


3201
AGGTATTTAT ATCACAGGCA AAGAAAAAGG TGTTTTAGCA GCGCAGGCAG


 


3251
GCAAAGACAT CAACATCATT GCCGGTCAAA TCAGCAATCA ATCAGATCAA


 


3301
GGGCAAACCC GGCTGCAGGC AGGACGCGAC ATTAACCTGG ATACGGTACA


 


3351
AACCGGCAAA TATCAAGAAA TCCATTTTGA TGCCGATAAC CATACCATCC


 


3401
GAGGTTCAAC GAACGAAGTC GGCAGCAGCA TTCAAACAAA AGGCGATGTT


 


3451
ACCCtatTGT CAGGGAATAA TCTCAATGCC AAAGCTGCCG AAGTCGGCAG


 


3501
CGCAAAAGGC ACACTTGCCG TGTATGCTAA AAATGACATT ACTATCAGCT


 


3551
CAGGCATCCA TGCCGGCCAA GTTGATGATG CGTCCAAACA TACAGGCAGA


 


3601
AGCGGCGGCG GTAATAAATT AGTCATTACC GATAAAGCCC AAAGTCATCA


 


3651
CGAAACTGCT CAAAGCAGCA CCTTTGAAGG CAAGCAAGTT GTATTGCAGG


 


3701
CAGGAAACGA TGCCAACATC CTTGGCAGTA ATGTTATTTC CGATAATGGC


 


3751
ACCCGGATTC AAGCAGGCAA TCATGTTCGC ATTGGTACAA CCCAAACTCA


 


3801
AAGCCAAAGC GAAACCTATC ATCAAACCCA AAAATCAGGA TTGATGAGTG


 


3851
CAGGTATCGG CTTCACTATT GGCAGCAAGA CAAACACACA AGAAAACCAA


 


3901
TCCCAAAGCA ACGAACATAC AGGCAGTACC GTAGGCAGCC TGAAAGGCGA


 


3951
TACCACCATT GTTGCAAGCA AACACTACGA ACAAACCGGC AGCAACGTTT


 


4001
CCAGCCCTGA GGGCAACAAC CTTATCAGCA CGCAAAGTAT GGATATTGGC


 


4051
GCAGCACAAA ACCAATTAAA CAGCAAAACC ACCCAAACCT ACGAACAAAA


 


4101
AGGCTTAACG GTGGGCATTC AGTTCGCCCG TTACCGATTT GGCACAACAA


 


4151
GCGATTGCCG TAGCACACAA AGCAGCAAAC AAGTCGGACA AAGCAAAAAC


 


4201
GACCGCGTTA ATGCCATGGC GGCTGCCAAT GCAGGTTGGC AGGCCTATCA


 


4251
AACAGGCAAA GGCGCACAAA ACTTAGCCAA TGGTACAACC AATGCCAAAC


 


4301
AAGTCAGCAT CTCCATAACC TACGGCGAAC AGCAAAACCG ACAAACCACC


 


4351
CAAGTTCAAG CCAATCAAGC CCAAGCGAGT CAAATTCAAG CAGGCGGCAA


 


4401
AACTACCCTT TATTGCCGAA GGTGCGGCGA ACAATCCAAT ATCAACATCA


 


4451
CAGGCTCAGG TGTTTCAGGC AGAGCAGGAA CCGGCCTGAT TGCCGATAAG


 


4501
CAAATCCATC TGCAATCAGC CGAGCAAAGC AATACCGAAC GCAGCCAAAA


 


4551
CAAATCAGCA GGCTGGAACG CAGGTGCTGC CGTATCATTC GGACAAGGAG


 


4601
GCTGGTCATT AGGCGTTGCC GCAGGCGGCA ATGTCGGCAA AGGCTACGGC


 


4651
TATGGCGATA GCGTAACCCA CCGCCATAGC CATATTGGCG ACAAAGGCAG


 


4701
CCAAACCCTT ATCCAAAGTG GTGGCGATAC CATCATCAAA GGCGCGCAAG


 


4751
TACGCGGCAA AGGCGTACAA GTCAATGCCA AAAACCTAAG CATTCAAAGT


 


4801
GTACAAGATA GAGAAACTTA TCAAAGCAAA CAACAAAACG CCGGTGCACA


 


4851
AGTTACCGTA GGTTATGGCT TCAGTGCCAG TGGCGATTAC AGCCAAAGCA


 


4901
AAATCCGAGC CGACCATGCT TCGGTAACCG AGCAAAGCGG TATTTATGCC


 


4951
GGAGAAGACG GCTATCAAAT CAAGGTCGGA AACCATACAG GCCTCAAAGG


 


5001
CGGCATCATC ACCAGCAGCC AAAGCGCAAA AGACAAGGGT AAAAACCGAT


 


5051
TCAGCACAGG CACACTCGCC GGCAGTGATA TTCAAAATTA CAGCCAATAC


 


5101
GAAGGAAAAA GTTTTGGATT GGGTGCCAGC GTTGCCGTAA GCGGCAAAAC


 


5151
ACTGGGACAG GGCGCAAAAA ATAAACCTCA AGACAAACAC CTGACAAGCA


 


5201
TAGCCGATAA AAACGGCGCA AGTTCATCAG TAGGGTACGG CAGCGACAGC


 


5251
GACAGTCAAA GCAGCATCAC AAAAAGCGGC ATCAATACCC CCAAAAACAT


 


5301
TCAAATCACA GACGAAGCCG CACAAATCAG GCTGACAGGC AAAATAGCGG


 


5351
CACAAACCAA AGCCGATATT GATACAAACG TAACCACAGA CACCGCCGAA


 


5401
CGACATTCGG GCAGCCTGAA AAACATATTT GACAAAGATA GAGTGCAAAG


 


5451
TGAACTGGAT TTACAAAgaA CCGTCAGCCA AGATTTTAGT AAAAATGTTC


 


5501
AACAAACCAA TACCGAGATT AACCAACATT TAGACAAACT CAAAGCAGAC


 


5551
AAAGAAGCAG CCGAAACAGC AGCAGCCGAG GCATTAGCCA ATGGCGATAT


 


5601
GGAAACTGCC AAACGCAAAG CCCATGAAGC TCAAGATGCG GCAGCAAAAG


 


5651
CAGATAATTG GCAACAAGGC AAAGTCATTC TCAACATGTT AGCCTCAGGT


 


5701
TTAGCTGAGC CGACCCAAAG CGGAGCgggc ATCGCTGCGG CTACCGCATC


 


5751
GCCagaCGTA TCGTATGCGA TTGGACAGCA CTTTAAagaT TTAGCCGGTC


 


5801
AAAACGCGAA TGGCAAACTA ACCGCCAGTC AagaAACCGC TCACGTTCTT


 


5851
GCCCACGCGG TATTAGGAGC AGCGGTTGCC GCAGCATGAG GCAACAATGC


 


5901
CCCGGCAGGA GCATTGGGTG CGGGCGGGTc ggAagcggCC GCCCCAATCA


 


5951
TCGGCAAATG GCTGTACGGC AAAGGAGAcg gcggcagccT GAATgcggag


 


6001
gaaaAAGaga CCGTTTCGGC GATTACAAGG ATGCTGggta cGgctGCCGG


 


6051
AGCAGCTGAG GGAAACTCGT CCGCCGATGC TGTGTGGGGT TGTTTTcaaa


 


6101
cggctTCaga TTTCGCTTCC TCTTTTTCAT ATCCTATAAA CATGTGA






This corresponds to the amino acid sequence <SEQ ID 1666; ORF 563.ng>:










g563.pep..




1
MNKTLYRVIF NRKRGAVVAV AETTKREGKS CADSGSGSVY VKSVSFIPTH


 


51
SKAFCFSALG FSLCLALGTV NIAFADGIIT DKAAPKTQQA TILQTGNGIP


 


101
QVNIQTPTSA GVSVNQYAQF DVGNRGAILN NSRSNTQTQL GGWIQGNPWL


 


151
TRGEARVVVN QINSSHPSQL NGYIEVGGRR AEVVIANPAG IAVNGGGFIN


 


201
ASRATLTTGQ PQYQAGDFSG FKIRQGNAVI AGHGLDARDT DFTRILLYAN


 


251
KITLISTAEQ AGIRNQGQLF ASSGNVAIDA NGRLVNSGTM AAANVQDMNN


 


301
TAEHKVNIRS QAFENSGTAV SQQGTQIHSQ SIQNTGKLLS AGTEDLAVSG


 


351
SLNNQNGEIA TNQQLIIHDG QQSTVVIDNT NGTIQSGRDV AIQAKSLSNN


 


401
GTLAADNKLD IALQDDFYVE RKIVAGNELS LSTRGSLKNS HTLQAGKRIR


 


451
IKANNLDNAV QGNIQSGGTT DIGTQHNLTN RGLIDGQQTK IQAGQMNNIG


 


501
TGRIYGDNIA IAATRLDNQD ENGTGAAIAA RENLNLGIEQ LNNRENSLIY


 


551
SGNDMAVGGA LDTNDQATGK AQRIHNAGAI IEAAGKMRLG VEKLHNTNEH


 


601
LKTQLVETGR ERIVDYEAFG RHELLREGTQ HELGWFVYNN ESDHLRTPDG


 


651
VAHENWHKYD YEKVTQETQV TGTAPAKIIA GSDLIIDSKA VFNSDSRIIA


 


701
GGQLLVQTEK DGLHNEQTFG EKKVFSENGK LHNYWRARRK GHDETGHREQ


 


751
NYTLPEEITR DISLGSFAYE SHSKALSRHA PSQGTELPQS NRDNIRTAKS


 


801
NGISLPYTPN SFTPLPGSSL YIINPANKGY LVETDPRFAN YRQWLGSDYM


 


851
LGSLKLDPNN LHKRLGDGYY EQRLINEQIA ELTGHRRLDG YQNDEEQFKA


 


901
LMDNGATAAR SMNLSVGIAL SAEQAAQLTS DIVWLVQKEV KLPDGGTQTV


 


951
LMPQVYVRVK NGGIDGKGAL LSGSNTQINV SGSLKNSGTI AGRNALIINT


 


1001
DTLDNIGGRI HAQKSAVTAT QDINNIGGIL SAEQTLLLNA GNNINNQSTA


 


1051
KSSQNAQGSS TYLDRMAGIY ITGKEKGVLA AQAGKDINII AGQISNQSDQ


 


1101
GQTRLQAGRD INLDTVQTGK YQEIHFDADN HTIRGSTNEV GSSIQTKGDV


 


1151
TLLSGNNLNA KAAEVGSAKG TLAVYAKNDI TISSGIHAGQ VDDASKHTGR


 


1201
SGGGNKLVIT DKAQSHHETA QSSTFEGKQV VLQAGNDANI LGSNVISDNG


 


1251
TRIQAGNHVR IGTTQTQSQS ETYHQTQKSG LMSAGIGFTI GSKTNTQENQ


 


1301
SQSNEHTGST VGSLKGDTTI VASKHYEQTG SNVSSPEGNN LISTQSMDIG


 


1351
AAQNQLNSKT TQTYEQKGLT VGIQFARYRF GTTSDCRSTQ SSKQVGQSKN


 


1401
DRVNAMAAAN AGWQAYQTGK GAQNLANGTT NAKQVSISIT YGEQQNRQTT


 


1451
QVQANQAQAS QIQAGGKTTL YCRRCGEQSN INITGSGVSG RAGTGLIADK


 


1501
QIHLQSAEQS NTERSQNKSA GWNAGAAVSF GQGGWSLGVA AGGNVGKGYG


 


1551
YGDSVTHRHS HIGDKGSQTL IQSGGDTIIK GAQVRGKGVQ VNAKNLSIQS


 


1601
VQDRETYQSK QQNAGAQVTV GYGFSASGDY SQSKIRADHA SVTEQSGIYA


 


1651
GEDGYQIKVG NHTGLKGGII TSSQSAKDKG KNRFSTGTLA GSDIQNYSQY


 


1701
EGKSFGLGAS VAVSGKTLGQ GAKNKPQDKH LTSIADKNGA SSSVGYGSDS


 


1751
DSQSSITKSG INTPKNIQIT DEAAQIRLTG KIAAQTKADI DTNVTTDTAE


 


1801
RHSGSLKNIF DKDRVQSELD LQRTVSQDFS KNVQQTNTEI NQHLDKLKAD


 


1851
KEAAETAAAE ALANGDMETA KRKAHEAQDA AAKADNWQQG KVILNMLASG


 


1901
LAEPTQSGAG IAAATASPDV SYAIGQHFKD LAGQNANGKL TASQETAHVL


 


1951
AHAVLGAAVA AAXGNNAPAG ALGAGGSEAA APIIGKWLYG KGDGGSLNAE


 


2001
EKETVSAITR MLGTAAGAAE GNSSADAVWG CFQTASDFAS SFSYPINM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1667>:










m563.seq..




1
ATGAATAAAA CTCTCTATCG TGTAATTTTC AACCGCAAAC GTGGGGCTGT


 


51
GGTAGCCGTT GCTGAAACTA CCAAGCGCGA AGGTAAAAGC TGTGCCGATA


 


101
GTGATTCAGG CAGCGCTCAT GTGAAATCTG TTCCTTTTGG TACTACTCAT


 


151
GCACCTGTTT GTCGTTCAAA TATCTTTTCT TTTTCTTTAT TGGGCTTTTC


 


201
TTTATGTTTG GCTGTAGGTA CGGCCAATAT TGCTTTTGCT GATGGCATTA


 


251
TTGCTGATAA AGCTGCTCCT AAAACTCAAC AAGCCACGAT TCTGCAAACA


 


301
GGTAACGGCA TACCGCAAGT CAATATTCAA ACCCCTACTT CGGCAGGGGT


 


351
TTCTGTTAAT CAATACGCCC AGTTTGATGT GGGTAATCGC GGGGCGATTT


 


401
TAAACAACAG CCGCAGCAAC ACCCAAACAC AGCTAGGCGG TTGGATTCAA


 


451
GGTAATCCTT GGTTGGCAAG GGGCGAAGCA CGTGTGGTTG TAAACCAAAT


 


501
CAACAGCAGC CATTCTTCAC AAATGAATGG CTATATTGAA GTGGGCGGAC


 


551
GACGTGCAGA AGTCGTTATT GCCAATCCGG CAGGGATTGC AGTCAATGGT


 


601
GGTGGTTTTA TCAATGCTTC CCGTGCCACT TTGACGACAG GCCAACCGCA


 


651
ATATCAAGCA GGAGACCTTA GCGGCTTTAA GATAAGGCAA GGCAATGTTG


 


701
TAATCGCCGG ACACGGTTTG GATGCCCGTG ATACCGATTT CACACGTATT


 


751
CTCAGTTATC ATTCCAAAAT TGATGCACCC GTATGGGGAC AAGATGTTCG


 


801
TGTCGTCGCG GGACAAAACG ATGTGGTCGC AACAGGTAAT GCACATTCGC


 


851
CTATTCTCAA TAATGCTGCT GCCAATACGT CAAACAATAC AGCCAACAAC


 


901
GGCACACATA TCCCTTTATT TGCGATTGAT ACAGGCAAAT TAGGAGGTAT


 


951
GTATGCCAAC AAAATCACCT TGATCAGTAC GGCCGAGCAA GCAGGCATTC


 


1001
GTAATCAAGG GCAGTTGTTT GCTTCTTCCG GTAATGTGGC GATTGATGCA


 


1051
AATGGCCGTT TAGTCAATAG TGGCACGATG GCTGCCGCCA ATGCGAAAGA


 


1101
TACGGATAAT ACAGCGGAAC ACAAAGTCAA TATCCGCAGT CAGGGCGTTG


 


1151
AAAACAGCGG TACGGCGGTA TCGCAACAAG GCACTCAAAT TCACAGTCAG


 


1201
TCGATTCAAA ACACTGGCAC ATTATTGTCC TCAGGCGAAA TATTGATTCA


 


1251
CAATTCGGGC AGCCTGAAAA ATGAAACATC AGGCACCATT GAAGCCGCTC


 


1301
GTTTGGCTAT TGATACCGAC ACACTTAATA ATCAAGGCAA ACTCTCTCAA


 


1351
ACAGGTTCAC AAAAACTCCA TATTGATGCA CAAGGCAAAA TGGATAACCG


 


1401
TGGCCGCATG GGTTTACAAG ATACCGCACC AACCGCGTCA AATGGTTCAA


 


1451
GCAATCAAAC CGGCAATAGT TACAATGCAT CTTTCCATTC ATCCACTACC


 


1501
ACACCAACAA CGGCAACAGG TACGGGTACT GCAACCGTTT CTATATCAAA


 


1551
CATAACTGCG CCTACCTTTG CTGATGGGAC AATTCGCACT CATGGTGCAC


 


1601
TGGATAATTC AGGCAGTATT ATTGCCAATG GTCAAACAGA TGTTAGTGCG


 


1651
CAACAAGGTT TAAATAATGC AGGACAAATA GACATTCATC AGTTAAATGC


 


1701
AAAAGGTTCG GCGTTTGACA ATCACAATGG AACAATTATC AGTGATGCGG


 


1751
TCCACATTCA AGCCGGCAGC CTGAATAATC AAAATGGCAA CATCACAACA


 


1801
CGCCAACAGT TAGAGATTGA AACCGATCAA CTGGATAACG CTCATGGCAA


 


1851
GTTATTATCA GCAGAAATAG CGGATTTAGC CGTTTCAGGC AGCCTGAACA


 


1901
ATCAAAATGG CGAAATAGCG ACCAATCAAC AACTGATTAT TCACGATGGT


 


1951
CAGCAATCTA CCGCTGTCAT TGATAATACG AATGGCACGA TACAATCAGG


 


2001
CCGTGATGTT GCTATTCAGG CAAAATCGTT ATCCAACAAC GGCACACTTG


 


2051
CCGCTGATAA TAAACTGGAT ATTGCGTTAC AAGATGATTT TTATGTAGAA


 


2101
CGCAATATCG TGGCGGGCAA TGAATTGTCG CTCAGTACAC GAGGCAGCCT


 


2151
GAAAAATTCA CATACTTTGC AAGCAGGAAA ACGCATTCGG ATTAAAGCAA


 


2201
ATAACCTTGA TAATGCAGCA CAAGGCAACA TTCAATCCGG CGGTACGACA


 


2251
GACATTGGCA CGCAGCACAA TTTAACCAAT AGAGGCTTGA TTGACGGACA


 


2301
ACAAACCAAA ATCCAAGCCG GGCAAATGAA TAATATCGGT ACAGGTCGGA


 


2351
TTTATGGCGA CAATATCGCT ATTGCGGCTA CCCGCTTAGA CAATCAAGAT


 


2401
GAAAACGGTA CAGGTGCCGC CATTGCGGCA CGTGAAAACC TGAATTTAGG


 


2451
CATCGGACAA TTAAACAACC GTGAAAACAG TCTGATTTAC AGCGGTAACG


 


2501
ATATGGCGGT TGGCGGCGCA TTAGATACCA ATGGCCAAGC CACAGGCAAA


 


2551
GCCCAAAGGA TACACAATGC CGGCGCAACC ATTGAAGCTG CAGGCAAAAT


 


2601
GCGTTTAGGT GTAGAAAAGC TGCACAATAC CAATGAGCAT TTGAAAACGC


 


2651
AGTTGGTAGA AACAGGGCGC GAGCATATTG TTGATTACGA AGCATTTGGA


 


2701
CGACACGAAT TATTGCGAGA AGGCACGCAA CATGAATTAG GCTGGTCTGT


 


2751
CTATAACGAT GAATCAGACC ACTTACGCAC CCCTGATGGA GCGGCGCATG


 


2801
AAAATTGGCA TAAATACGAT TATGAAAAAG TCACCCAAAA AACCCAAGTT


 


2851
ACCCAAACTG CGCCAGCCAA AATCATTTCA GGTAATGATT TAACCATTGA


 


2901
TGGTAAAGAA GTATTTAATA CCGATAGCCA AATCATTGCT GGTGGCAATC


 


2951
TCATTGTACA AACAGAAAAA GACGGTTTGC ATAACGAGCA AACCTTTGGC


 


3001
GAAAAGAAAG TATTCAGTGA AAATGGCAAA TTACACAGCT ATTGGCGTGA


 


3051
GAAACATAAA GGACGAGACT CAACGGGACA TAGCGAACAA AATTACACTT


 


3101
TGCCGGAGGA AATCACACGC AACATTTCAC TGGGTTCATT TGCCTATGAA


 


3151
TCGCATCGCA AAGCATTAAG CCATCATGCG CCCAGCCAAG GCACTGAGTT


 


3201
GCCGCAAAGC AACGGTATTT CGCTACCCTA TACGTCCAAT TCTTTTACCC


 


3251
CATTACCCAG CAGCAGCTTA TACATTATCA ATCCTGTCAA TAAAGGCTAT


 


3301
CTTGTTGAAA CCGATCCACG CTTTGCCAAC TACCGTCAAT GGTTGGGTAG


 


3351
TGACTATATG CTGGACAGCC TCAAACTAGA CCCAAACAAT TTACATAAAC


 


3401
GTTTGGGTGA TGGTTATTAC GAGCAACGTT TAATCAATGA ACAAATCGCA


 


3451
GAGCTGACAG GGCATCGTCG TTTAGACGGT TATCAAAACG ACGAAGAACA


 


3501
ATTTAAAGCC TTAATGGATA ATGGCGCGAC TGCGGCACGT TCGATGAATC


 


3551
TCAGCGTTGG CATTGCATTA AGTGCCGAGC AAGTAGCGCA ACTGACCAGC


 


3601
GATATTGTTT GGTTGGTACA AAAAGAAGTT AAGCTTCCTG ATGGCGGCAC


 


3651
ACAAACCGTA TTGGTGCCAC AGGTTTATGT ACGCGTTAAA AATGGCGACA


 


3701
TAGACGGTAA AGGTGCATTG TTGTCAGGCA GCAATACACA AATCAATGTT


 


3751
TCAGGCAGCC TGAAAAACTC AGGCACGATT GCAGGGCGCA ATGCGCTTAT


 


3801
TATCAATACC GATACGCTAG ACAATATCGG TGGGCGTATT CATGCGCAAA


 


3851
AATCAGCGGT TACGGCCACA CAAGACATCA ATAATATTGG CGGCATGCTT


 


3901
TCTGCCGAAC AGACATTATT GCTCAACGCA GGCAACAACA TCAACAGCCA


 


3951
AAGCACCACC GCCAGCAGTC AAAATACACA AGGCAGCAGC ACCTACCTAG


 


4001
ACCGAATGGC AGGTATTTAT ATCACAGGCA AAGAAAAAGG TGTTTTAGCA


 


4051
GCGCAGGCAG GAAAAGACAT CAACATCATT GCCGGTCAAA TCAGCAATCA


 


4101
ATCAGAGCAA GGGCAAACCC GGCTGCAAGC AGGGCGCGAC ATTAACCTAG


 


4151
ATACGGTACA AACCAGCAAA CATCAAGCAA CCCATTTTGA TGCCGATAAC


 


4201
CATGTTATTC GCGGTTCAAC GAACGAAGTC GGCAGCAGCA TTCAAACAAA


 


4251
AGGCGATGTT ACCCTATTGT CAGGGAATAA CCTCAATGCC AAAGCTGCCG


 


4301
AAGTCAGCAG CGCAAACGGT ACACTCGCTG TGTCTGCCAA AAATGACATC


 


4351
AACATCAGCG CAGGCATCAA CACGACCCAT GTTGATGATG CGTCCAAACA


 


4401
CACAGGCAGA AGCGGTGGTG GCAATAAATT AGTCATTACC GATAAAGCCC


 


4451
AAAGTCATCA CGAAACCGCC CAAAGCAGCA CCTTTGAAGG CAAGCAAGTT


 


4501
GTATTGCAGG CAGGAAACGA TGCCAACATC CTTGGCAGCA ATGTTATTTC


 


4551
CGATAATGGC ACCCAGATTC AAGCAGGCAA TCATGTTCGC ATTGGTACAA


 


4601
CCCAAACTCA AAGCCAAAGC GAAACCTATC ATCAAACCCA GAAATCAGGA


 


4651
TTGATGAGTG CAGGTATCGG CTTCACTATT GGCAGCAAGA CAAACACACA


 


4701
AGAAAACCAA TCCCAAAGCA ACGAACATAC AGGCAGTACC GTAGGCAGCT


 


4751
TGAAAGGCGA TACCACCATT GTTGCAGGCA AACACTACGA ACAAATCGGC


 


4801
AGTACCGTTT CCAGCCCGGA AGGCAACAAT ACCATCTATG CCCAAAGCAT


 


4851
AGACATTCAA GCGGCACACA ACAAATTAAA CAGTAATACC ACCCAAACCT


 


4901
ATGAACAAAA AGGCCTAACG GTGGCATTCA GTTCGCCCGT TACCGATTTG


 


4951
GCACAACAAG CGATTGCCGT AGCACAAAGC AGCAAACAAG TCGGACAAAG


 


5001
CAAAAACGAC CGCGTTAATG CCATGGCGGC TGCCAATGCA GGCTGGCAAG


 


5051
CCTATCAAAC AGGTAAGAGT GCACAAAACT TAGCCAATGG TACAACCAAT


 


5101
GCCAAACAAG TCAGCATCTC CATAACCTAC GGCGAACAGC AAAACCGACA


 


5151
AACCACCCAA GTTCAAGCCA ATCAAGCCCA AGCGAGTCAA ATTCAAGCAG


 


5201
GTGGTAAAAC CACATTAATC GCCACAGGCG CAGCAGAACA ATCCAATATC


 


5251
AACATCGCAG GCTCAGATGT TGCCGGCAAA GCAGGCACAA TCCTGATTGC


 


5301
CGATAACGAC ATCACACTCC AATCAGCCGA GCAAAGCAAT ACCGAACGCG


 


5351
GCCAAAACAA ATCGGCAGGC TGGAACGCAG GTGCTGCCGT ATCATTCGGA


 


5401
CAAGGAGGCT GGTCATTAGG CGTTACCGCA GGCGGCAATG TCGGCAAAGG


 


5451
CTACGGCAAT GGCGACAGCA TCACCCACCG CCATAGCCAT ATCGGCGACA


 


5501
AAGGCAGCCA AACCCTTATC CAAAGCGGTG GCGACACTAC CATCAAAGGC


 


5551
GCGCAAGTAC GCGGCAAAGG CGTACAAGTC AATGCCAAAA ACCTAAGTAT


 


5601
TCAAAGCGTA CAAGATAGAG AAACCTATCA AAGCAAACAA CAAAACGCCA


 


5651
GTGCACAAGT TACCGTAGGT TATGGCTTCA GTGCCGGTGG CGATTACAGC


 


5701
CAAAGCAAAA TCCGAGCCGA CCATGTTTCA GTAACCGAGC AAAGCGGTAT


 


5751
TTATGCCGGA GAAGACGGCT ATCAAATCAA GGTCGGAAAC CATACAGACC


 


5801
TCAAAGGCGG CATCATCACC AGTACCCAAA GCGCAGAAGA CAAGGGTAAA


 


5851
AACCGCTTTC AGACGGCCAC CCTCACCCAT AGCGACATCA AAAACCACAG


 


5901
CCAATACAAA GGCGAAAGTT TTGGATTGGG CGCAAGTGCG TCCATAAGCG


 


5951
GCAAAACACT GGGACAGGGC GCACAAAATA AACCTCAAAA CAAACACCTG


 


6001
ACAAGCGTAG CCGATAAAAA CAGCGCAAGT TCATCAGTGG GTTATGGCAG


 


6051
CGACAGCGAC AGTCAAAGCA GCATCACAAA AAGCGGCATC AACACCCGCA


 


6101
ACATTCAAAT CACCGACGAA GCCGCACAAA TCCGGCTGAC AGGCAAAACA


 


6151
GCGGCACAAA CCAAAGCCGA TATTGATACA AACGTAACCA CAGACACCGC


 


6201
CGAACGACAT TCGGGCAGCT TGAAGAACAC CTTCAACAAA GAAGCGGTGC


 


6251
AAAGTGAACT GGATTTACAA AGAACCGTCA GCCAAGATTT TAGTAAAAAT


 


6301
GTTCAACAAG CCAATACCGA GATTAACCAA CATTTAGACA AACTCAAAGC


 


6351
AGACAAAGAA GCAGCCGAAA CAGCAGCAGC CGAGGCATTA GCCAATGGCG


 


6401
ATATGGAAAC TGCCAAACGC AAAGCCCATG AAGCTCAAGA TGCGGCAGCA


 


6451
AAAGCAGATA ATTGGCAACA AGGCAAAGTC ATTCTCAACA TGTTAGCCTC


 


6501
AGGTTTAGCT GCGCCGACCC AAAGCGGAGC GGGCATCGCT GCGGCTACCG


 


6551
CATCGCCAGC CGTATCGTAT GCGATTGGAC AGCACTTTAA AGATTTAGCC


 


6601
GGTCAAAACG CGAATGGTAA ACTAACCGCC AGTCAAGAAA CCGCACACGT


 


6651
TCTTGCCCAC GCGGTATTAG GAGCAGCGGT TGCCGCAGTA GGAGACAACA


 


6701
ATGCTCTAGC AGGAGCATTG AGTGCGGGCG GGTCGGAAGC GGCTGCGCCT


 


6751
TACATCAGCA AATGGTTATA CGGCAAAGAA AAAGGAAGCG ACTTAACGGC


 


6801
GGAAGAGAAA GAGACTGTAA CAGCGATTAC AAATGTATTG GGTACGGCTA


 


6851
CGGGTGCGGC AGTCGGCAAC AGCGCAACAG ATGCAGCGCA AGGCAGCCTG


 


6901
AATGCGCAAA GTGCGGTGGA GAATAATGAT ACTGTAGAGC AAGTGAAATT


 


6951
TGCTCTTAGG CACCCTAGAA TTGCTATTGC AATTGGATCT GTACATAAAG


 


7001
ATCCTGGCTC TACATTAGAG CCTAATATTT CAACAATTGC TTCAACTTTT


 


7051
CAATTAAATT TATTTCCTAA TAGTGAATTT GGTGGTGAAG GTGGAGTTGG


 


7101
CAATGCATTC AGGCACGTTT TATGGCAAGC AACCATCACA CGAGAATTTG


 


7151
GCAAAGATAT TGCTGTTAAA GTAGGAAATA GTCATGAAAG TGGGGAAAAA


 


7201
ATTAATTATT CTATAAGACG TAATCTTTCA TTAGATAAAG CAGATGAAAT


 


7251
GATTGATCAA CTAAATAACG AAATAGGAAG AGAAATAGCA TTAAATACCA


 


7301
ATAGGTTAAA CACAAAAGAG TTAGTTGGAT TAATTCTGGA AACTTATAAA


 


7351
AATAATGGTT TTTATCAAGC AGAAAGAAAC AGTAATGGAA ATTATGATGT


 


7401
TGTAAGAAAA AGATTATCTG AAAAAGATTA CCAGAATACA AGCAATATAT


 


7451
TGATTCACTT AGATAATACT GGTGCCGGAT TTAAAATTCA GCAGAGGAGA


 


7501
AAACAAATCA GAGCACAAAT TTCAGCCAGA CAATGGAGAA GATAA






This corresponds to the amino acid sequence <SEQ ID 1668; ORF 563>:










m563.pep..




1
MNKTLYRVIF NRKRGAVVAV AETTKREGKS CADSDSGSAH VKSVPFGTTH


 


51
APVCRSNIFS FSLLGFSLCL AVGTANIAFA DGIIADKAAP KTQQATILQT


 


101
GNGIPQVNIQ TPTSAGVSVN QYAQFDVGNR GAILNNSRSN TQTQLGGWIQ


 


151
GNPWLARGEA RVVVNQINSS HSSQMNGYIE VGGRRAEVVI ANPAGIAVNG


 


201
GGFINASRAT LTTGQPQYQA GDLSGFKIRQ GNVVIAGHGL DARDTDFTRI


 


251
LSYHSKIDAP VWGQDVRVVA GQNDVVATGN AHSPILNNAA ANTSNNTANN


 


301
GTHIPLFAID TGKLGGMYAN KITLISTAEQ AGIRNQGQLF ASSGNVAIDA


 


351
NGRLVNSGTM AAANAKDTDN TAEHKVNIRS QGVENSGTAV SQQGTQIHSQ


 


401
SIQNTGTLLS SGEILIHNSG SLKNETSGTI EAARLAIDTD TLNNQGKLSQ


 


451
TGSQKLHIDA QGKMDNRGRM GLQDTAPTAS NGSSNQTGNS YNASFHSSTT


 


501
TPTTATGTGT ATVSISNITA PTFADGTIRT HGALDNSGSI IANGQTDVSA


 


551
QQGLNNAGQI DIHQLNAKGS AFDNHNGTII SDAVHIQAGS LNNQNGNITT


 


601
RQQLEIETDQ LDNAHGKLLS AEIADLAVSG SLNNQNGEIA TNQQLIIHDG


 


651
QQSTAVIDNT NGTIQSGRDV AIQAKSLSNN GTLAADNKLD IALQDDFYVE


 


701
RNIVAGNELS LSTRGSLKNS HTLQAGKRIR IKANNLDNAA QGNIQSGGTT


 


751
DIGTQHNLTN RGLIDGQQTK IQAGQMNNIG TGRIYGDNIA IAATRLDNQD


 


801
ENGTGAAIAA RENLNLGIGQ LNNRENSLIY SGNDMAVGGA LDTNGQATGK


 


851
AQRIHNAGAT IEAAGKMRLG VEKLHNTNEH LKTQLVETGR EHIVDYEAFG


 


901
RHELLREGTQ HELGWSVYND ESDHLRTPDG AAHENWHKYD YEKVTQKTQV


 


951
TQTAPAKIIS GNDLTIDGKE VFNTDSQIIA GGNLIVQTEK DGLHNEQTFG


 


1001
EKKVFSENGK LHSYWREKHK GRDSTGHSEQ NYTLPEEITR NISLGSFAYE


 


1051
SHRKALSHHA PSQGTELPQS NGISLPYTSN SFTPLPSSSL YIINPVNKGY


 


1101
LVETDPRFAN YRQWLGSDYM LDSLKLDPNN LHKRLGDGYY EQRLINEQIA


 


1151
ELTGHRRLDG YQNDEEQFKA LMDNGATAAR SMNLSVGIAL SAEQVAQLTS


 


1201
DIVWLVQKEV KLPDGGTQTV LVPQVYVRVK NGDIDGKGAL LSGSNTQINV


 


1251
SGSLKNSGTI AGRNALIINT DTLDNIGGRI HAQKSAVTAT QDINNIGGML


 


1301
SAEQTLLLNA GNNINSQSTT ASSQNTQGSS TYLDRMAGIY ITGKEKGVLA


 


1351
AQAGKDINII AGQISNQSEQ GQTRLQAGRD INLDTVQTSK HQATHFDADN


 


1401
HVIRGSTNEV GSSIQTKGDV TLLSGNNLNA KAAEVSSANG TLAVSAKNDI


 


1451
NISAGINTTH VDDASKHTGR SGGGNKLVIT DKAQSHHETA QSSTFEGKQV


 


1501
VLQAGNDANI LGSNVISDNG TQIQAGNHVR IGTTQTQSQS ETYHQTQKSG


 


1551
LMSAGIGFTI GSKTNTQENQ SQSNEHTGST VGSLKGDTTI VAGKHYEQIG


 


1601
STVSSPEGNN TIYAQSIDIQ AAHNKLNSNT TQTYEQKGLT VAFSSPVTDL


 


1651
AQQAIAVAQS SKQVGQSKND RVNAMAAANA GWQAYQTGKS AQNLANGTTN


 


1701
AKQVSISITY GEQQNRQTTQ VQANQAQASQ IQAGGKTTLI ATGAAEQSNI


 


1751
NIAGSDVAGK AGTILIADND ITLQSAEQSN TERGQNKSAG WNAGAAVSFG


 


1801
QGGWSLGVTA GGNVGKGYGN GDSITHRHSH IGDKGSQTLI QSGGDTTIKG


 


1851
AQVRGKGVQV NAKNLSIQSV QDRETYQSKQ QNASAQVTVG YGFSAGGDYS


 


1901
QSKIRADHVS VTEQSGIYAG EDGYQIKVGN HTDLKGGIIT STQSAEDKGK


 


1951
NRFQTATLTH SDIKNHSQYK GESFGLGASA SISGKTLGQG AQNKPQNKHL


 


2001
TSVADKNSAS SSVGYGSDSD SQSSITKSGI NTRNIQITDE AAQIRLTGKT


 


2051
AAQTKADIDT NVTTDTAERH SGSLKNTFNK EAVQSELDLQ RTVSQDFSKN


 


2101
VQQANTEINQ HLDKLKADKE AAETAAAEAL ANGDMETAKR KAHEAQDAAA


 


2151
KADNWQQGKV ILNMLASGLA APTQSGAGIA AATASPAVSY AIGQHFKDLA


 


2201
GQNANGKLTA SQETAHVLAH AVLGAAVAAV GDNNALAGAL SAGGSEAAAP


 


2251
YISKWLYGKE KGSDLTAEEK ETVTAITNVL GTATGAAVGN SATDAAQGSL


 


2301
NAQSAVENND TVEQVKFALR HPRIAIAIGS VHKDPGSTLE PNISTIASTF


 


2351
QLNLFPNSEF GGEGGVGNAF RHVLWQATIT REFGKDIAVK VGNSHESGEK


 


2401
INYSIRRNLS LDKADEMIDQ LNNEIGREIA LNTNRLNTKE LVGLILETYK


 


2451
NNGFYQAERN SNGNYDVVRK RLSEKDYQNT SNILIHLDNT GAGFKIQQRR


 


2501
KQIRAQISAR QWRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 563 shows 79.1% identity over a 2316 aa overlap with a predicted ORF (ORF 563.ng) from N. gonorrhoeae:











The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1669>:










m564.seq




1
ATGAACCGCA CCCTGTACAA AGTTGTATTT AACAAACATC GAAACTGCAT


 


51
GATAGCCGTT GCTGAAAATG CCAAACGCGA GGGCAAAAAC ACAGCCGACA


 


101
CCCAAGCTGT AGGTATTTTG CCAAATGATA TTGCGGGCTT TGCGGGTTTT


 


151
ATCCATTCTA TCTCTGTTAT CTCATTCTCC CTTTCATTAC TGCTCGGTTC


 


201
TGCCCTTATC CTGACTTCTT CTTCTGCTAC TGCCCAAGGT ATCGTTGCCG


 


251
ACAAATCCGC ACCTGCACAG CAACAGCCTA CCATCCTGCA AACAGGTAAC


 


301
GGCATACCGC AAGTCAATAT TCAAACCCCT ACTTCGGCAG GGGTTTCTGT


 


351
TAATCAATAC GCCCAGTTTG ATGTGGGTAA TCGCGGGGCG ATTTTAAACA


 


401
ACAGTCGCAG CAACACCCAA ACACAGCTAG GCGGTTGGAT TCAAGGCAAT


 


451
CCTTGGTTGG CAAGGGGCGA AGCACGTGTG GTTGTAAACC AAATCAACAG


 


501
CAGCCATTCT TCACAACTGA ATGGCTATAT TGAAGTGGGC GGACGACGTG


 


551
CAGAAGTCGT TATTGCCAAT CCGGCAGGGA TTGCAGTCAA TGGTGGTGGT


 


601
TTTATCAATG CTTCCCGTGC CACTTTGACG ACAGCCCAAC CGCAATATCA


 


651
AGCAGGAGAC CTTAGCGGCT TTAAGATAAG GCAAGGCAAT GTTGTAATCG


 


701
CCGGACACGG TTTGGATGCA CGTGATACCG ATTACACACG TATTCTCAGT


 


751
TATCATTCCA AAATTGATGC ACCCGTATGG GGACAAGATG TTCGTGTCGT


 


801
CGCGGGACAA AACGATGTGG CCGCAACAGG TGATGCACAT TCGCCTATTC


 


851
TCAATAATGC TGCTGCCAAT ACGTCAAACA ATACAGCCAA CAACGGCACA


 


901
CATATCCCTT TATTTGCGAT TGATACAGGC AAATTAGGAG GTATGTATGC


 


951
CAACAAAATC ACCTTGATCA GTACGGTCGA GCAAGCAGGC ATTCGTAATC


 


1001
AAGGGCAATG GTTTGCCTCA GCCGGCAATG TGGCAGTGAA TGCTGAGGGT


 


1051
AAACTGGTCA ACACGGGCAT GATTGCAGCG ACGGGAGAAA ATCATGCGGT


 


1101
TTCACTTCAT GCCGGCAATG TTCATAATAG CGGTACGGTT GCCTCACAGG


 


1151
ATGATGCCAA TATTCACAGC CAGACGCTGG ACAATTCAGG TACGGTCTTA


 


1201
TCCTCAGGTC GATTGACTGT TCGTAATTTA GGCCGTCTGA AAAACCAAAA


 


1251
CAACGGTACG ATCCAGGCTG CCCGCTTAGA TATGTCAACA GGTGGTTTGG


 


1301
ATAACACAGG TAATATTACT CAAACAGGTT CACAAGCATT GGATTTGGTA


 


1351
TCTGCCGGCA AATTCGATAA CAGTGGCAAG ATTGGTGTAA GTGACGTTCC


 


1401
ACAGACCGGT TTGAATCCCA ATCCATCAGT CATACCACAG ATTCCGAGTA


 


1451
CTGCAACAGG TTCAGGCAGC AGCACTGTCT CGGTATCTAA GCCTGGTTCA


 


1501
AACAATCCCG TTTCACCTAC AGCACCTGCA AAAAACTACG CCGTAGGACG


 


1551
CATTCAAACA ACAGGAGCAT TTGACAATGC AGGATCAATT AATGCGGGTG


 


1601
GGCAAATTGA CATTGCCGCC CAAAACGGTT TGGGAAATTC GGGTAGTCTG


 


1651
AATGCGGCTA AACTACGAGT ATCAGGCGAT TCATTTAACA ATACGGTAAA


 


1701
AGGCAAACTC CAGGCACACG ATCTGGCTGT TAACACTCAA ACTGCTAAAA


 


1751
ACAGCGGTCA CTTATTAACT CAAACCGGCA AGATTGATAA CCGTGAACTG


 


1801
CATAATGCCG GAGAAATTGC CGCCAACAAT CTGACACTCA TTCATTCGGG


 


1851
CCGCTTGAGC AATGATAAAA AAGGCAATAT TCGAGCTGCA CATTTACAGC


 


1901
TTGATACCGC CGGTTTACAT AATGCAGGTA ACATTCTTGC CGATAGTGGA


 


1951
ACCGTTACCA CCAAGAATAA TCTTCGCAAT ACAGGAAAAG TTTCTGTTGC


 


2001
ACGACTGAAT ACCGAAGGTC AGACTCTAGA TAATACGCGC GGACGTATAG


 


2051
AGGCTGAAAC GGTTAACATC CAAAGTCAGC AACTGACTAA CCAAAGCGGC


 


2101
CATATTACTG CTACCGAACA ACTGACTATC AATAGTCGAA ATGTAGACAA


 


2151
CCAAAACGGC AAACTCCTAT CTGCAAACCA AGCACAATTA GCTGTTTCAG


 


2201
ACGGCCTATA CAACCAACAT GGTGAAATTG CCACCAACCG GCAGTTGTCT


 


2251
ATTCACGATA AAAATCAAAA CACTTTGGCG TTAAACAATG CGGATGGCAC


 


2301
GATTCAATCT GCCGGTAATG TATCGCTACA AGCCAAATCA CTCGCCAACA


 


2351
ATGGCACATT AACAGCCGGT AACAAACTGG ATATTGCTTT GACGGACGAT


 


2401
TTCGTCGTAG AGCGCGACCT CACTGCAGGC AAACAATTAA ATCTAAGCAT


 


2451
AAAAGGCCGT CTGAAAAATA CCCATACCCT ACAAGCAGGC CATACGCTCA


 


2501
AACTCAATGC CGGCAATATA GATAACCAAG TTACAGGCAA AATTATTGGT


 


2551
GGAGAACAAA CGGACATCAC ATCCGAACAG CATGTTGACA ACAGGGGCTT


 


2601
GATCAACAGC GACGGTTTGA CCCACATCGG TGCAGGTCAA ACCCTGACCA


 


2651
ACACCGGGAC AGGCAAAATC TATGGCAACC ATATTGCCCT GGACGCGCAA


 


2701
ATACTGCTTA ACCGGGAAGA AACGACGGAA GGCAGTACCA AAGCGGGGGC


 


2751
AATAGCTGCA AGGAAACGTT TGGATATTGG AGCGAAAGAG ATTCATAACC


 


2801
AAGAAGGTGC CCTACTATCC AGCGAAGGTA TTTTTGCCGT AgGTAATCGA


 


2851
CTGGATGAAC AACATCATGC GGCAGGCATG GCCGATACCT TTGTTAATGG


 


2901
CAGTGCCGGT TTGGAAGTAC AAGGTGATGC ATTGATGTCC GTTCGGAATA


 


2951
TGCAGAATAT CAATAATCAC TTTAAAACAG AGACATACTT AGCCAAAGCG


 


3001
GAAAAGCAAG TCCGCGACTA CACCGTACTG GGGCAAAATA CCTACTATCA


 


3051
GGCGGGAAAA GACGGTTTAT TCGACAACTC GCAAGGACAA AAAGACCAAA


 


3101
CTACTGCTAC GTTCCATTTA AAAAATGGTT CTCGTATTGA GGCCAACCAA


 


3151
TGGCATGTCC GAGACTACCA CATCGAGACT TATAAAGAAC GCATCATCGA


 


3201
AAACCGGCCG GCACACATTA CTGTGGGCGG TGATTTGACT GCCTCAGGTC


 


3251
AAAATTGGCT GAACAAAGAC AGCCGGATTG TAGTAGGCGG GCGTATTATC


 


3301
ACTGATGATT TAAACCAGAA AGAAATTACC AATCAAAGTA CAACAGGCAA


 


3351
AGGTCGCACA GATGCTGTCG GCACACAGTG GGATTCAGTT ACAAAAAAAG


 


3401
GATGGTACAG CGGTAGAAAA AGACAACGCC GTACTGAAAG AAACCATACT


 


3451
CCTTACCATG ATACCCAACT ATTTACCCAC GACTTCGACA CGCCTGTATC


 


3501
CGTCATCCAA CAGAATGCCG CCTCCCCTTC CTTTCAACCC GCCGCATCTG


 


3551
CAATCAAACT GATTGACGGA GTATCCACGG CAGCCGTCAA TGGTCAGCGC


 


3601
ATCCATACCG GTAATGTGGT CTCGTTAAAT AACGCTACTG TTACTCTGCC


 


3651
TAACAGCAGC CTCTATACCA CCCATCCTGA CAATAAAGGC TGGTTGGTTG


 


3701
AAACCGATCC TCAATTTGCA GACTACCGCC GCTGGTTGGG CAGCGACTAC


 


3751
ATGTTGCAAC AACTGCAATT GGACACCAAT CATCTACACA AACGGCTTGG


 


3801
CGACGGCTAC TACGAACAAA AACTTGTTAA TGAACAAATC CATCAGTTAA


 


3851
CAGGCTACCG CCGACTCGAC GGCTACAGGA GTGATGAAGA ACAATTCAAA


 


3901
GCTCTGATGG ACAACGGCCT TACTGCTGCC AAAACATTCG GTCTCACCCC


 


3951
AGGTATCGCC TTGAGTGCAG AGCAAGTTGC CCGCTTAACT TCAGATATCG


 


4001
TTTGGATGGA AAATCAAACC GTCACCCTGT CTGACGGTTC GACTCAAACC


 


4051
GTACTGGTTC CTAAAGTCTA TGCCCTGGCG CGCAAAGGTG ATCTCAATAC


 


4101
CTCCGGTGGC CTGATTAGTG CCGAACAAGT CTTACTTAAA CTGCAAAACG


 


4151
GCAACCTGAC TAACAGCGGT ACCATTGCGG GGCGACAGGC CGTACTCATC


 


4201
CAGGCACGGA ATATTAACAG CAACGGTAAC ATTCAAGCCG ACCAAATCGG


 


4251
CTTAAAAGCT GAAAAAAGTA TCAATATCGA CGGCGGGCAG GTACAAGCAG


 


4301
GCAGACTGCT GACTGCCCAA GCGCAAAATA TCAACCTTAA CGGTACAACC


 


4351
CAAACTTCCG GTAATGAACG TAACGGCAAT ACCGCCATCG ATCGTATGGC


 


4401
CGGCATTAAC GTGGTCGGAA GCCATACTGA ACAAGTAGAT AACAGAACTT


 


4451
CAGACGGCAT CCTATCCCTG CATGCCAGCA ACGATATCAA CCTCAATGCG


 


4501
GCCACCGTCT CTAACCAAGT TAAAGACGGC ACTACCCAAA TTACCGCCGG


 


4551
CAATAATCTC AACCTCGGCA CCATCCGTAC CGAACATCGC GAAGCCTATG


 


4601
GTACATTAGA TGACGAGAAC CATCGCCATG TCCGCCAAAG TACCGAAGTC


 


4651
GGCAGCAGTA TCCGCACGCA AAACGGCGCA CTGCTTAGAG CCGGTAACGA


 


4701
CTTAAAAATC CGCCAAGGCG AACTGGAGGC CGAAGAAGGC AAAACCGTCC


 


4751
TTGCCGCAGG ACGTGATGTC ACTATCAGCG AAGGACGCCA AATAACCGAA


 


4801
CTGGATACCT CGGTAAGCGG AAAAAGCAAA GGCATCCTTT CCAGTACCAA


 


4851
AACACACGAC CGCTACCGCT TCAGTCATGA TGAAGCAGTC GGCAGCAACA


 


4901
TCGGCGGCGG CAAAATGATT GTTGCAGCCG GGCAGGATAT CAATGTACGC


 


4951
GGCAGCAACC TTATTTCTGA TAAGGGCATT GTTTTAAAAG CAGGACACGA


 


5001
CATCGATATT TCTACTGCCC ATAATCGCTA TACCGGCAAT GAATACCACG


 


5051
AGAGCAAAAA ATCAGGCGTC ATGGGTACTG GCGGATTGGG CTTTACTATC


 


5101
GGTAACCGGA AAACTACCGA TGACACTGAT CGTACCAATA TTGTCCATAC


 


5151
AGGCAGCATT ATAGGCAGCC TGAATGGAGA CACCGTTACA GTTGCAGGAA


 


5201
ACCGCTACCG ACAAACCGGC AGTACCGTCT CCAGCCCCGA GGGGCGCAAT


 


5251
ACCGTCACAG CCAAAAGCAT AGATGTAGAG TTCGCAAACA ACCGGTATGC


 


5301
CACTGACTAC GCCCATACCC AGGAACAAAA AGGCCTTACC GTCGCCCTCA


 


5351
ATGTCCCGGT TGTCCAAGCT GCACAAAACT TCATACAAGC AGCCCAAAAT


 


5401
GTGGGCAAAA GTAAAAATAA ACGCGTTAAT GCCATGGCTG CAGCCAATGC


 


5451
TGCATGGCAG AGTTATCAAG CAAAACAACA AATGCAACAA TTTGCTCCAA


 


5501
GCAGCAGTGC GGGACAAGGT CAAAACAACA ATCAAAGCCC CAGTATCAGT


 


5551
GTGTCCATTA CCTACGGCGA ACAGAAAAGT CGTAACGAGC AAAAAAGACA


 


5601
TTACACCGAA GCGGCAGCAA GTCAAATTAT CGGCAAAGGG CAAACCACAC


 


5651
TTGCGGCAAC AGGAAGTGGG GAGCAGTCCA ATATCAATAT TACAGGTTCC


 


5701
GATGTCATCG GCCATGCAGG TACTGCCCTC ATTGCCGACA ACCATATCAG


 


5751
ACTCCAATCT GCCAAACAGG ACGGCAGCGA GCAAAGCAAA AACAAAAGCA


 


5801
GTGGTTGGAA TGCAGGCGTA GCCGTCAAAA TAGGCAACGG CATCAGGTTT


 


5851
GGAATTACCG CCGGAGGAAA TATCGGTAAA GGTAAAGAGC AAGGGGGAAG


 


5901
TACTACCCAC CGCCACACCC ATGTCGGCAG CACAACCGGC AAAACTACCA


 


5951
TCCGAAGCGG CGGGGATACC ACCCTCAAAG GTGTGCAGCT CATCGGCAAA


 


6001
GGCATACAGG CAGATACGCG CAACCTGCAT ATAGAAAGTG TTCAAGATAC


 


6051
TGAAACCTAT CAGAGCAAAC AGCAAAACGG CAATGTCCAA GTTACTGTCG


 


6101
GTTACGGATT CAGTGCAAGC GGCAGTTACC GCCAAAGCAA AGTCAAAGCA


 


6151
GACCATGCCT CCGTAACCGG GCAAAGCGGT ATTTATGCCG GAGAAGACGG


 


6201
CTATCAAATC AAAGTCAGAG ACAACACAGA CCTCAAGGGC GGTATCATCA


 


6251
CGTCTAGCCA AAGCGCAGAA GATAAGGGCA AAAACCTTTT TCAGACGGCC


 


6301
ACCCTTACTG CCAGCGACAT TCAAAACCAC AGCCGCTACG AAGGCAGAAG


 


6351
CTTCGGCATA GGCGGCAGTT TCGACCTGAA CGGCGGCTGG GACGGCACGG


 


6401
TTACCGACAA ACAAGGCAGG CCTACCGACA GGATAAGCCC GGCAGCCGGC


 


6451
TACGGCAGCG ACGGAGACAG CAAAAACAGC ACCACCCGCA GCGGCGTCAA


 


6501
CACCCACAAC ATACACATCA CCGACGAAGC GGGACAACTT GCCCGAACAG


 


6551
GCAGGACTGC AAAAGAAACC GAAGCGCGTA TCTACACCGG CATCGACACC


 


6601
GAAACTGCGG ATCAACACTC AGGCCATCTG AAAAACAGCT TCGACAAAGA


 


6651
CGCGGTCGCC AAAGAGATCA ACCTGCAAAG GGAAGTAACG AAGGAGTTCG


 


6701
GCAGAAACGC CGCCCAAGCC GTAGCGGCCG TTGCCGACAA ACTCGGCAAT


 


6751
ACCCAAAGTT ACGAACGGTA TCAGGAAGCC CGAACCCTGC TGGAGGCCGA


 


6801
ACTGCAAAAC ACGGACAGCG AAGCCGAAAA AGCCGCCTTC CGCGCATCCC


 


6851
TCGGCCAAGT AAACGCCTAT CTTGCCGAAA ACCAAAGCCG CTACGACACC


 


6901
TGGAAAGAAG GCGGCATAGG CAGGAGCATA CTGCACGGGG CGGCAGGCGG


 


6951
ACTGACGACC GGCAGCCTCG GCGGCATACT GGCCGGCGGC GGCACTTCCC


 


7001
TTGCCGCACC GTATTTGGAC AAAGCGGCGG AAAACCTCGG TCCGGCGGGC


 


7051
AAAGCGGCGG TCAACGCACT GGGCGGTGCG GCCATCGGCT ATGCAACTGG


 


7101
TGGTAGTGGT GGTGCTGTGG TGGGTGCGAA TGTAGATTGG AACAATAGGC


 


7151
AGCTGCATCC GAAAGAAATG GCGTTGGCCG ACAAATATGC CGAAGCCCTC


 


7201
AAGCGCGAAG TTGAAAAACG CGAAGGCAGA AAAATCAGCA GCCAAGAAGC


 


7251
GGCAATGAGA ATCCGCAGGC AGATACTGCG TTGGGTGGAC AAAGGTTCCC


 


7301
AAGACGGCTA TACCGACCAA AGCGTCATAT CCCTTATCGG AATGAAAGGC


 


7351
GAAGACAAAG CCTTGGGTTA TACTTGGGAC TACCGCGACT ACGGCGCAAG


 


7401
AAATCCGCAA ACCTACAACG ATCCGAAGCT GTTTGAGGAA TACCGCCGAC


 


7451
AGGACAAACC CGAATACCGC AACCTGACCT GGCTGCACAG CGGGACGAAA


 


7501
GACACCAAAA TCAGGCAGGG AGAGCGGAAA AACGAAGAGT TTGCACTGAA


 


7551
CGTTGCCGAA GGACTGACGA GCCTTGTCAA CCCCAATCCG AGGATAAAAG


 


7601
TCCCGATTCT TGCAGGCATC CGCAACCTGA AAAACATCAA GCCGACAGTT


 


7651
ACCGGCAGCG ATCCCTTATT GGCGGGTGCG GGGAATATCC GTATCCCTGC


 


7701
AAACGGCAAT GTTGCGAAGG GGGACAGGAT TCCGGATACG GCATTGGCTA


 


7751
GCAAGGGAAT CAAACATAAA GATCGTAAAG ATCAACTGGA GAAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 1670; ORF 564>:










m564.pep




1
MNRTLYKVVF NKHRNCMIAV AENAKREGKN TADTQAVGIL PNDIAGFAGF


 


51
IHSISVISFS LSLLLGSALI LTSSSATAQG IVADKSAPAQ QQPTILQTGN


 


101
GIPQVNIQTP TSAGVSVNQY AQFDVGNRGA ILNNSRSNTQ TQLGGWIQGN


 


151
PWLARGEARV VVNQINSSHS SQLNGYIEVG GRRAEVVIAN PAGIAVNGGG


 


201
FINASRATLT TAQPQYQAGD LSGFKIRQGN VVIAGHGLDA RDTDYTRILS


 


251
YHSKIDAPVW GQDVRVVAGQ NDVAATGDAH SPILNNAAAN TSNNTANNGT


 


301
HIPLFAIDTG KLGGMYANKI TLISTVEQAG IRNQGQWFAS AGNVAVNAEG


 


351
KLVNTGMIAA TGENHAVSLH ARNVHNSGTV ASQDDANIHS QTLDNSGTVL


 


401
SSGRLTVRNL GRLKNQNNGT IQAARLDMST GGLDNTGNIT QTGSQALDLV


 


451
SAGKFDNSGK IGVSDVPQTG LNPNPSVIPQ IPSTATGSGS STVSVSKPGS


 


501
NNPVSPTAPA KNYAVGRIQT TGAFDNAGSI NAGGQIDIAA QNGLGNSGSL


 


551
NAAKLRVSGD SFNNTVKGKL QAHDLAVNTQ TAKNSGHLLT QTGKIDNREL


 


601
HNAGEIAANN LTLIHSGRLS NDKKGNIRAA HLQLDTAGLH NAGNILADSG


 


651
TVTTKNNLRN TGKVSVARLN TEGQTLDNTR GRIEAETVNI QSQQLTNQSG


 


701
HITATEQLTI NSRNVDNQNG KLLSANQAQL AVSDGLYNQH GEIATNRQLS


 


751
IHDKNQNTLA LNNADGTIQS AGNVSLQAKS LANNGTLTAG NKLDIALTDD


 


801
FVVERDLTAG KQLNLSIKGR LKNTHTLQAG HTLKLNAGNI DNQVTGKIIG


 


851
GEQTDITSEQ HVDNRGLINS DGLTHIGAGQ TLTNTGTGKI YGNHIALDAQ


 


901
ILLNREETTE GSTKAGAIAA RKRLDIGAKE IHNQEGALLS SEGIFAVGNR


 


951
LDEQHHAAGM ADTFVNGSAG LEVQGDALMS VRNMQNINNH FKTETYLAKA


 


1001
EKQVRDYTVL GQNTYYQAGK DGLFDNSQGQ KDQTTATFHL KNGSRIEANQ


 


1051
WHVRDYHIET YKERIIENRP AHITVGGDLT ASGQNWLNKD SRIVVGGRII


 


1101
TDDLNQKEIT NQSTTGKGRT DAVGTQWDSV TKKGWYSGRK RQRRTERNHT


 


1151
PYHDTQLFTH DFDTPVSVIQ QNAASPSFQP AASAIKLIDG VSTAAVNGQR


 


1201
IHTGNVVSLN NATVTLPNSS LYTTHPDNKG WLVETDPQFA DYRRWLGSDY


 


1251
MLQQLQLDTN HLHKRLGDGY YEQKLVNEQI HQLTGYRRLD GYRSDEEQFK


 


1301
ALMDNGLTAA KTFGLTPGIA LSAEQVARLT SDIVWMENQT VTLSDGSTQT


 


1351
VLVPKVYALA RKGDLNTSGG LISAEQVLLK LQNGNLTNSG TIAGRQAVLI


 


1401
QARNINSNGN IQADQIGLKA EKSINIDGGQ VQAGRLLTAQ AQNINLNGTT


 


1451
QTSGNERNGN TAIDRMAGIN VVGSHTEQVD NRTSDGILSL HASNDINLNA


 


1501
ATVSNQVKDG TTQITAGNNL NLGTIRTEHR EAYGTLDDEN HRHVRQSTEV


 


1551
GSSIRTQNGA LLRAGNDLKI RQGELEAEEG KTVLAAGRDV TISEGRQITE


 


1601
LDTSVSGKSK GILSSTKTHD RYRFSHDEAV GSNIGGGKMI VAAGQDINVR


 


1651
GSNLISDKGI VLKAGHDIDI STAHNRYTGN EYHESKKSGV MGTGGLGFTI


 


1701
GNRKTTDDTD RTNIVHTGSI IGSLNGDTVT VAGNRYRQTG STVSSPEGRN


 


1751
TVTAKSIDVE FANNRYATDY AHTQEQKGLT VALNVPVVQA AQNFIQAAQN


 


1801
VGKSKNKRVN AMAAANAAWQ SYQATQQMQQ FAPSSSAGQG QNNNQSPSIS


 


1851
VSITYGEQKS RNEQKRHYTE AAASQIIGKG QTTLAATGSG EQSNINITGS


 


1901
DVIGHAGTAL IADNHIRLQS AKQDGSEQSK NKSSGWNAGV AVKIGNGIRF


 


1951
GITAGGNIGK GKEQGGSTTH RHTHVGSTTG KTTIRSGGDT TLKGVQLIGK


 


2001
GIQADTRNLH IESVQDTETY QSKQQNGNVQ VTVGYGFSAS GSYRQSKVKA


 


2051
DHASVTGQSG IYAGEDGYQI KVRDNTDLKG GIITSSQSAE DKGKNLFQTA


 


2101
TLTASDIQNH SRYEGRSFGI GGSFDLNGGW DGTVTDKQGR PTDRISPAAG


 


2151
YGSDGDSKNS TTRSGVNTHN IHITDEAGQL ARTGRTAKET EARIYTGIDT


 


2201
ETADQHSGHL KNSFDKDAVA KEINLQREVT KEFGRNAAQA VAAVADKLGN


 


2251
TQSYERYQEA RTLLEAELQN TDSEAEKAAF RASLGQVNAY LAENQSRYDT


 


2301
WKEGGIGRSI LHGAAGGLTT GSLGGILAGG GTSLAAPYLD KAAENLGPAG


 


2351
KAAVNALGGA AIGYATGGSG GAVVGANVDW NNRQLHPKEM ALADKYAEAL


 


2401
KREVEKREGR KISSQEAAMR IRRQILRWVD KGSQDGYTDQ SVISLIGMKG


 


2451
EDKALGYTWD YRDYGARNPQ TYNDPKLFEE YRRQDKPEYR NLTWLHSGTK


 


2501
DTKIRQGERK NEEFALNVAE GLTSLVNPNP RIKVPILAGI RNLKNIKPTV


 


2551
TGSDPLLAGA GNIRIPANGN VAKGDRIPDT ALASKGIKHK DRKDQLEKK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae














The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1671>:










g565.seq




1
atggacagca cattgtctaa aacgtgttgc gtttcgtgca tattgttgag


 


51
cgtaaccacc accattttcg cccgtcccag accggcggct tccaatactt


 


101
ccctgcgttt cgcatcgccg aacgacaccg gctcgcctgc acttctggct


 


151
acctgcacgc gtgcgatgtc caagtcgagc gcgaaatacg gaatatcctc


 


201
tttgggcgaa gacgcgtccg accgtctgcc cgcccctgcc gaagccgaca


 


251
atcagcacat gatcagactt gctcatcgct tccaccaaca tgctgtgcag


 


301
atcgagcgac ttcatgtccc agcttga






This corresponds to the amino acid sequence <SEQ ID 1672; ORF 565.ng>:










g565.pep




1
MDSTLSKTCC VSCILLSVTT TIFARPRPAA SNTSLRFASP NDTGSPALLA


 


51
TCTRAMSKSS AKYGISSLGE DASDRLPAPA EADNQHMIRL AHRFHQHAVQ


 


101
IERLHVPA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1673>:










m565.seq




1
ATGGACAGCA CATTGTCTAA AACGTGTTGC GTTTCGTGCA TATTGTTGAG


 


51
CGTAACCACC ACCATTTTCG CCCGTCCCAG ACCGGCGGCT TCCAATACTT


 


101
CCCTGCGTTT CGCATCGCCG AACGACACCG GTTCGCCCGC ACTTCTGGCA


 


151
ACCTGCACCC GCGCAATGTC CAAGTCGAGC GCGAAATACG GAATATCCTC


 


201
TTGGGCAAGG ACGCGTCCGA CCGTCTGCCC GCCCCTGCCG AAGCCGACAA


 


251
TCAGCACATG GTCGGACTTG CTCATGGTTT CTACCAGCAT ACTGTGCAGA


 


301
TCGAGCGACT TCATGTCCCA GCTTGACTTG ACCAAACGCC CGACCAGCGC


 


351
ATCGCTGCCG CCCAAGAGGA AGGGCGCGAT AATCATCGAC AGCAGAACCG


 


401
CCGCCGTCGC CGCCTGTTCC CATTCTGGCG AAACCATATC AAGCTGCCCG


 


451
GCAATGGCCA GCATCACGAA GCCGAACTCG CCGCCCTGCG CGAGATACAA


 


501
AGCCGTTTTG AGGCTGTCGC CGACCGAATG TTTCATTTTG AAGGCAATGG


 


551
CAAACACAAC CAGTGCCTTC AACACCAGCA GCATTGCCAA CAGCATCAAT


 


601
ACCTGCCGCC AGCCGCCGAT CAATGCCTGA






This corresponds to the amino acid sequence <SEQ ID 1674; ORF 565>:










m565.pep




1
MDSTLSKTCC VSCILLSVTT TIFARPRPAA SNTSLRFASP NDTGSPALLA


 


51
TCTRAMSKSS AKYGISSWAR TRPTVCPPLP KPTISTWSDL LMVSTSILCR


 


101
SSDFMSQLDL TKRPTSASLP PKRKGAIIID SRTAAVAACS HSGETISSCP


 


151
AMASITKPNS PPCARYKAVL RLSPTECFIL KAMANTTSAF NTSSIANSIN


 


201
TCRQPPINA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m565/g565 100.0% identity in 67 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1675>:










a565.seq




1
ATGGACAGCA CATTGTCTAA AACGTGTTGC GTTTCGTGCA TATTGTTGAG


 


51
CGTAACCACC ACCATTTTCG CCCGTCCCAG ACCGGCGGCT TCCAATACTT


 


101
CCCTGCGTTT CGCATCGCCG AACGACACCG GTTCGCCCGC ACTTCTGGCA


 


151
ACCTGCACCC GCGCAATGTC CAAGTCGAGC GCGAAATACG GAATATCCTC


 


201
TTGGGCAAGG ACGCGTCCGA CCGTCTGCCC GCCCCTGCCG AAGCCGACAA


 


251
TCAGCACATG GTCGGACTTG CTCATGGTTT CTACCAGCAT ACTGTGCAGA


 


301
TCGAGCGACT TCATGTCCCA GCTTGACTTG ACCAAACGCC CGACCAGTGC


 


351
ATCGCTGCCG CCCAAGAGGA AGGGCGCGAT AATCATCGAC AGCAGAACCG


 


401
CCGCCGTCGC CGCCTGTTCC CATTCTAGCG AAACCATATC AAGCTGCCCG


 


451
GCAATGGCCA GCATCACGAA GCCGAACTCG CCGCCCTGCG CGAGATACAA


 


501
AGCCGTTTTG AGGCTGTCGC CGACCGAATG TTTCATTTTG AAGGCAATGG


 


551
CAAACACAAC CAGTGCCTTC AACACCAGCA GCATTGCCAA CAGCATCAAT


 


601
ACCTGCCGCC AGCCGCCGAT TAATGCCTGA






This corresponds to the amino acid sequence <SEQ ID 1676; ORF 565.a>:










a565.pep




1
MDSTLSKTCC VSCILLSVTT TIFARPRPAA SNTSLRFASP NDTGSPALLA


 


51
TCTRAMSKSS AKYGISSWAR TRPTVCPPLP KPTISTWSDL LMVSTSILCR


 


101
SSDFMSQLDL TKRPTSASLP PKRKGAIIID SRTAAVAACS HSSETISSCP


 


151
AMASITKPNS PPCARYKAVL RLSPTECFIL KAMANTTSAF NTSSIANSIN


 


201
TCRQPPINA*






m565/a565 99.5% identity in 209 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1677>:










g566.seq..




1
atgccgtctg aacaatatct tttcagacgg cattttgtat gggggttaac


 


51
ggttgttcag cccgagtacg tcctgcatat cgtacaaacc cgttttgccg


 


101
tttacccaaa ctgcggcgcg gacggcaccg gcggcaaagg tcatgcggct


 


151
gccggctttg tgggtgattt ccacgcgttc gccgtcggtg gcgaagaggg


 


201
cggtgtggtc gccgactatg tcgcctgcgc ggacggtggc aaagccgatg


 


251
gtggaaggat cgcgcggacc agtgtggcct tcgcggccgt aaacggcgca


 


301
ttgtttgagg tcgcggccga gcgcgccggc gatgacttcg cccattcgta


 


351
a






This corresponds to the amino acid sequence <SEQ ID 1678; ORF 566.ng>:










g566.pep..




1
MPSEQYLFRR HFVWGLTVVQ PEYVLHIVQT RFAVYPNCGA DGTGGKGHAA


 


51
AGFVGDFHAF AVGGEEGGVV ADYVACADGG KADGGRIART SVAFAAVNGA


 


101
LFEVAAERAG DDFAHS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1679>:










m566.seq..




1
ATGCCGTCTG AACAATATCT TTTCAGACGG CATTTTGTAT GGGGGTTAAC


 


51
GGTTGTTCAG CCCGAGTACG TCCTGCATAT CGTACAAACC CGTTTTGCCG


 


101
TTGACCCAAA CTGCGGCGCG GACGGCACCG GCGGCAAAGG TCATGCGGCT


 


151
GCTGGCCTTG TGGGTGATTT CCACGCGCTC GCCGTCGGTG GCGAAGAGGG


 


201
CGGTGTGGTC GCCGACGATG TCGCCTGCGC GGACGGTGGC AAAGCCGATG


 


251
GTCGACGGAT CGCGCGGACC GGTGTGGCCT TCGCGGCCGT AAACGGCGCA


 


301
TTGTTTGAGG TCTCTGCCGA GCGCGCCGGC GATGACTTCG CCCATGCGTA


 


351
A






This corresponds to the amino acid sequence <SEQ ID 1680; ORF 566>:










m566.pep..




1
MPSEQYLFRR HFVWGLTVVQ PEYVLHIVQT RFAVDPNCGA DGTGGKGHAA


 


51
AGLVGDFHAL AVGGEEGGVV ADDVACADGG KADGRRIART GVAFAAVNGA


 


101
LFEVSAERAG DDFAHA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m566/g566 93.1% identity in 116 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1681>:










a566.seq




1
ATGCCGTCTG AACAATATCT TTTCAGACGG CATTTTGTAT GGGGGTTAAC


 


51
GGTTGTTCAG CCCGAGTACG TCCTGCATAT CGTACAAACC CGTTTTACCG


 


101
TTTACCCAAA CTGCGGCGCG GACGGCGCCG GCGGCAAAGG TCATGCGGCT


 


151
GCTTGCCTTG TGGGTGATTT CCACGCGCTC GCCGTCGGTG GCGAAGAGGG


 


201
CGGTGTGGTC GCCGACGATG TCGCCCGCGC GGACGGTGGC AAAGCCGATG


 


251
GTGGACGGAT CGCGCGGGCC GGTGTGGCCT TCGCGGCCGT AAACGGCGCA


 


301
TTGTTTGAGG TCTCTGCCGA GCGCGCCGGC GATGACTTCG CCCATGCGTA


 


351
A






This corresponds to the amino acid sequence <SEQ ID 1682; ORF 566.a>:










a566.pep




1
MPSEQYLFRR HFVWGLTVVQ PEYVLHIVQT RFTVYPNCGA DGAGGKGHAA


 


51
ACLVGDFHAL AVGGEEGGVV ADDVARADGG KADGGRIARA GVAFAAVNGA


 


101
LFEVSAERAG DDFAHA*






m566/a566 94.0% identity in 116 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1683>:










g567.seq..




1
atgcgacgac gggcagcggc atcgacaagg cgggtttgca gtccggcgtt


 


51
tatcaggtct tattgggcga tgcggacgtg cagtcggcgg cggtacgcag


 


101
caaagagggc ggatacggcg tgttgggtgc gaacgcgcgc gcttgccggc


 


151
gcggaaatcg agctggtgca ggaaatcgcc cgggaagtgc gtttgaaaaa


 


201
cgcgctcaag gcagtggcgg aagattacga ctttatcctg atcgactgtc


 


251
cgccttcgct gacgctgttg acgcttaacg gcttggtggc ggcgggcggc


 


301
gtgattgtgc cgatgttgtg cgaatattac gcgctggaag ggatttccga


 


351
tttgattgcg accgtgcgca aaatccgtca ggcggtcaat cccgatttgg


 


401
acatcacggg catcgtgcgt acgatgtacg acagccgcag caggctggtt


 


451
gccgaagtca gcgaacagtt gcgcagccat ttcggggatt tgctttttga


 


501
aaccgccatc ccgcgcaata tccgccttgc ggaagcgccg agccacggta


 


551
tgccggtgat ggcttacgac gcgcaggcaa agggtgccaa ggcgtatctt


 


601
gccttggcgg acgaactggc ggcgagggtg tcggggaaat ag






This corresponds to the amino acid sequence <SEQ ID 1684; ORF 567.ng>:










g567.pep




1
MRRRAAASTR RVCSPAFIRS YWAMRTCSRR RYAAKRADTA CWVRTRALAG


 


51
AEIELVQEIA REVRLKNALK AVAEDYDFIL IDCPPSLTLL TLNGLVAAGG


 


101
VIVPMLCEYY ALEGISDLIA TVRKIRQAVN PDLDITGIVR TMYDSRSRLV


 


151
AEVSEQLRSH FGDLLFETAI PRNIRLAEAP SHGMPVMAYD AQAKGAKAYL


 


201
ALADELAARV SGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1685>:










m567.seq..




1
ATGAGTGCGA ACATCCTTGC CATCGCCAAT CAGAAGGGCG GTGTGGGCAA


 


51
AACGACGACG ACGGTAAATT TGGCGGCTTC GCTGGCATCG CGCGGCAAAC


 


101
GCGTGCTGGT GGTCGATTTG GATCCGCAGG GCAATGCGAC GACGGGCAGC


 


151
GGCATCGACA AGGCGGGTTT GCAGTCCGGC GTTTATCAGG TCTTATTGGG


 


201
CGATGCGGAC GTGCAGTCGG CGGCGGTACG CAGCAAAGAG GGCGGATACG


 


251
CTGTGTTGGG TGCGAACCGC GCGCTGGCCG GCGCGGAAAT CGAACTGGTG


 


301
CAGGAAATCG CCCGGGAAGT GCGTTTGAAA AACGCGCTCA AGGCAGTGGA


 


351
AGAAGATTAC GACTTTATCC TGATCGACTG CCCGCCTTCG CTGACGCTGT


 


401
TGACGCTTAA CGGGCTGGTG GCGGCGGGCG GCGTGATTGT GCCGATGTTG


 


451
TGCGAATATT ACGCGCTGGA AGGGATTTCC GATTTGATTG CGACCGTGCG


 


501
CAAAATCCGT CAGGCGGTCA ATCCCGATTT GGACATCACG GGCATCGTGC


 


551
GCACGATGTA CGACAGCCGC AGCAGGCTGG TTGCCGAAGT CAGCGAACAG


 


601
TTGCGCAGCC ATTTCGGGGA TTTGCTTTTT GAAACCGTCA TCCCGCGCAA


 


651
TATCCGCCTT GCGGAAGCGC CGAGCCACGG TATGCCGGTG ATGGCTTACG


 


701
ACGCGCAGGC AAAGGGTACC AAGGCGTATC TTGCCTTGGC GGACGAGCTG


 


751
GCGGCGAGGG TGTCGGGGAA ATAG






This corresponds to the amino acid sequence <SEQ ID 1686; ORF 567>:










m567.pep..




1
MSANILAIAN QKGGVGKTTT TVNLAASLAS RGKRVLVVDL DPQGNATTGS


 


51
GIDKAGLQSG VYQVLLGDAD VQSAAVRSKE GGYAVLGANR ALAGAEIELV


 


101
QEIAREVRLK NALKAVEEDY DFILIDCPPS LTLLTLNGLV AAGGVIVPML


 


151
CEYYALEGIS DLIATVRKIR QAVNPDLDIT GIVRTMYDSR SRLVAEVSEQ


 


201
LRSHFGDLLF ETVIPRNIRL AEAPSHGMPV MAYDAQAKGT KAYLALADEL


 


251
AARVSGK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m567/g567 98.2% identity in 168 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1687>:










a567.seq




1
ATGAGTGCGA ACATCCTTGC CATCGCCAAT CAGAAGGGCG GTGTGGGCAA


 


51
AACGACGACG ACGGTAAATT TGGCGGCTTC GCTGGCATCG CGCGGCAAAC


 


101
GCGTGCTGGT GGTCGATTTG GATCCGCAGG GCAATGCGAC GACGGGCAGC


 


151
GGCATCGACA AGGCGAGTTT GCAGTCCGGC GTTTATCAGG TCTTATTGGG


 


201
CGATGCGGAC GTGAAATCGG CGGCGGTACG CAGCAAAGAG GGCGGATACG


 


251
GCGTGTTGGG TGCGAACCGC GCGCTGGCCG GCGCGGAAAT CGAGCTGGTG


 


301
CAGGAAATCG CCCGGGAAGT GCGTTTGAAA AACGCGCTCA AGGCAGTGGC


 


351
GGAAGATTAC GACTTTATCC TGATCGACTG CCCGCCTTCG CTGACGCTGT


 


401
TGACGCTTAA CGGCTTGGTG GCGGCAGGCG GCGTGATTGT GCCGATGTTG


 


451
TGCGAATATT ACGCGCTGGA AGGGATTTCC GATTTGATTG CGACCGTGCG


 


501
CAAAATCCGT CAGGCGGTCA ATCCCGATTT GGATATCACG GGCATCGTGC


 


551
GTACGATGTA CGACAGCCGC AGCAGGCTAG TTGCCGAAGT CAGCGAACAG


 


601
TTGCGCAGCC ATTTCGGGGA TTTGCTGTTT GAAACCGTCA TCCCGCGCAA


 


651
TATCCGCCTT GCGGAAGCGC CGAGCCACGG TATGCCGGTG ATGGCTTATG


 


701
ATGCGCAGGC AAAGGGTGCC AAGGCGTATC TTGCCTTGGC GGACGAGCTG


 


751
ATGGCGAGGG TGTCGGGGAA ATAG






This corresponds to the amino acid sequence <SEQ ID 1688; ORF 567.a>:










a567.pep




1
MSANILAIAN QKGGVGKTTT TVNLAASLAS RGKRVLVVDL DPQGNATTGS


 


51
GIDKASLQSG VYQVLLGDAD VKSAAVRSKE GGYGVLGANR ALAGAEIELV


 


101
QEIAREVRLK NALKAVAEDY DFILIDCPPS LTLLTLNGLV AAGGVIVPML


 


151
CEYYALEGIS DLIATVRKIR QAVNPDLDIT GIVRTMYDSR SRLVAEVSEQ


 


201
LRSHFGDLLF ETVIPRNIRL AEAPSHGMPV MAYDAQAKGA KAYLALADEL


 


251
MARVSGK*






m567/a567 97.7% identity in 257 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1689>:










g568.seq




1
atgctcaggg tcagaccggt attatttgcc gtcaaggctt ccgcctcttc


 


51
gataccttgc agaatctgcc gattaaagcg ttcgcggctg cccaatattt


 


101
tcaggcgcat attgttttcg tgcaggcggc gtacctgttt ttgcaaagcc


 


151
tgtaaaaaca gccccatcag gaacgaaact tcgtcttcgg ggcgacgcca


 


201
gttttcggtt gaaaaggcaa acacggtcag atattgcacg cccagtttgg


 


251
cgcaatgctt caccatattt tccaacgcgt ccaagccgcg tttgtgtccc


 


301
attatacgcg ggagaaaacg ttttttcgcc caacggccgt tgccgtccat


 


351
aattacggcg atgtgcctcg ggatggcggt gtgttccaaa atggtctgcg


 


401
tgctgctctt catatctgcc tttcgcggtt cggcgttcaa atgccgtctg


 


451
aacgccgcgc cgtga






This corresponds to the amino acid sequence <SEQ ID 1690; ORF 568.ng>:










g568.pep




1
MLRVRPVLFA VKASASSIPC RICRLKRSRL PNIFRRILFS CRRRTCFCKA


 


51
CKNSPIRNET SSSGRRQFSV EKANTVRYCT PSLAQCFTIF SNASKPRLCP


 


101
IIRGRKRFFA QRPLPSIITA MCLGMAVCSK MVCVLLFISA FRGSAFKCRL


 


151
NAAP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1691>:










m568.seq




1
ATGCTCAGGG TCAGGCCGGT ATTGTTTGCC GTCAACGCTT CCGCCTCTTC


 


51
GATGCCTTGC AGAATCTGCC GGTTGAAGCG TTCGCGGCTG CCCAATATCT


 


101
TCAGGCGCAT ATTGTTTTCG TGCAGGCGGC GTACCTGTTT TTGCAAAGCC


 


151
TGTAAAAACA GCCCCATCAG GAACGAAACT TCGTCTTCGG GGCGGCGCCA


 


201
GTTTTCGGTT GAAAAGGCAA ACACGGTCAG ATATTGCACA CCCAGTTTGG


 


251
CGCAATGCTT CACCATATTT TCCAATGCGT CCAAACCGCG TTTGTGTCCC


 


301
ATTATGCGCG GGAGGAAACG TTTTTTCGCC CAACGGCCGT TGCCGTCCAT


 


351
AATCACGGCG ATATGCTTGG GAATGGCGGT GTGTTCCAAA ACGGCCTGCG


 


401
TGCTGCTTTT CATGTCTGCC TTTCGCGGTT CGGCATTCAA ATGCCGTCTG


 


451
AACGCCGAAC CGTGCAGGTT AAATTGCCAT CAAATCTTCT TCTTTGGCAG


 


501
TCAGGAGTTT GTCGGCTTCG GTAATGTATT TGTCGGTCAG TTTTTGAACC


 


551
GCTTCTTCGC CGCGACGTGC CTCGTCTTCG GAAATTTCTT TGTCTTTGAG


 


601
GAGTTTTTTG ATGTGGTCGT TGGCATCGCG GCGCACGTTG CGGATAGAGA


 


651
CGCGGCCTTC TTCCGCTTCG CCGCGTACGA CTTTAATCAG GTCTTTGCGG


 


701
CGTTCCTCGG TCAGCATGGG CATCGGCACG CGGATCAGGT CGCCGACAGC


 


751
TGCCGGGTTC AGTCCCAAGT TTGA






This corresponds to the amino acid sequence <SEQ ID 1692; ORF 568>:










m568.pep..




1
MLRVRPVLFA VNASASSMPC RICRLKRSRL PNIFRRILFS CRRRTCFCKA


 


51
CKNSPIRNET SSSGRRQFSV EKANTVRYCT PSLAQCFTIF SNASKPRLCP


 


101
IMRGRKRFFA QRPLPSIITA ICLGMAVCSK TACVLLFMSA FRGSAFKCRL


 


151
NAEPCRLNCH QIFFFGSQEF VGFGNVFVGQ FLNRFFAATC LVFGNFFVFE


 


201
EFFDVVVGIA AHVADRDAAF FRFAAYDFNQ VFAAFLGQHG HRHADQVADS


 


251
CRVQSQV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m568/g568 94.8% identity in 154 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1693>:










a568.seq




1
ATGCTCAGGG TCAGGCCGGT ATTGTTTGCC GTCAAGGCTT CCGCCTCTTC


 


51
GATGCCCTTC AGGATTTGAC GGTTGAAGCG TTCGCGGCTG CCCAGTATTT


 


101
TCAGGCGCAT ATTGTTTTCG TGCAGGCGGC GTACCTGTTT TTGCAAAGCC


 


151
TGTAAAAACA GCCCCATCAG GAACGAAACT TCGTCTTCGG GGCGGCGCCA


 


201
GTTTTCGGTT GAAAAGGCAA ACACGGTCAG ATATTGCACA CCCAGTTTGG


 


251
CGCAATGCTT CACCATATTT TCCAATGCGT CCAAACCGCG TTTGTGTCCC


 


301
ATTATGCGCG GGAGGAAACG TTTTTTCGCC CAACGGCCGT TGCCGTCCAT


 


351
AATCACGGCG ATATGCTTGG GAATGGCGGT GTGTTCCAAA ACGGCCTGCG


 


401
TGCTGCTTTT CATGTCTGCC TTTCGCGGTT CGGCATTCAA ATGCCGTCTG


 


451
AACGCCGAAC CGTGCAGGTT AAATTGCCAT CAAATCTTCT TCTTTGGCAG


 


501
TCAGGAGTTT GTCGGCTTCG GTAATGTATT TGTCGGTCAG TTTTTGAACC


 


551
GCTTCTTCGC CGCGACGTGC CTCGTCTTCG GAAATTTCTT TGTCTTTGAG


 


601
GAGTTTTTTG ATGTGGTCGT TGGCATCGCG GCGCACGTTG CGGATGGAGA


 


651
CGCGGCCTTC TTCCGCTTCG CCGCGTACGA CTTTAATCAG GTCTTTGCGG


 


701
CGTTCCTCGG TCAGCATGGG CATCGGCACG CGGATCAGGT CGCCGACAGC


 


751
TGCCGGGTTC AGTCCCAAGT TTGA






This corresponds to the amino acid sequence <SEQ ID 1694; ORF 568.a>:










a568.pep




1
MLRVRPVLFA VKASASSMPF RI*RLKRSRL PSIFRRILFS CRRRTCFCKA


 


51
CKNSPIRNET SSSGRRQFSV EKANTVRYCT PSLAQCFTIF SNASKPRLCP


 


101
IMRGRKRFFA QRPLPSIITA ICLGMAVCSK TACVLLFMSA FRGSAFKCRL


 


151
NAEPCRLNCH QIFFFGSQEF VGFGNVFVGQ FLNRFFAATC LVFGNFFVFE


 


201
EFFDVVVGIA AHVADGDAAF FRFAAYDFNQ VFAAFLGQHG HRHADQVADS


 


251
CRVQSQV*






m568/a568 98.1% identity in 257 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1695>:










g569.seq..




1
atgctgaaac aacgggtaat aaccgctatg tggctgctgc cgctgatgct


 


51
gggcatgctg ttttacgcgc cgcaatggct gtgggctgca ttttgcgggc


 


101
tgattgccct gaccgccttg tgggagtatg cccgtatggc cggtttgtgc


 


151
aaaaccgaaa ccaaccatta cctcgccgca accttggttt tcggcgtagt


 


201
tgcctatgcg ggcggctgga tgctgcctaa tttggtttgg tatgttgttt


 


251
tggcattttg gctcgccgtt atgcctttgt ggttgagatt caaatggagg


 


301
ctcaacggcg gttggcaggt ttatgccgtc ggctggcttt tgctcatgcc


 


351
gttttggttc gcgctcgtat ccctggcgcc cgcatcccga tga






This corresponds to the amino acid sequence <SEQ ID 1696; ORF 569.ng>:










g569.pep




1
MLKQRVITAM WLLPLMLGML FYAPQWLWAA FCGLIALTAL WEYARMAGLC


 


51
KTETNHYLAA TLVFGVVAYA GGWMLPNLVW YVVLAFWLAV MPLWLRFKWR


 


101
LNGGWQVYAV GWLLLMPFWF ALVSLAPASR *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1697>:










m569.seq..




1
ATGCTGAAAC AACGGGTAAT AACCGCCATG TGGCTGCTGC CGCTGATGCT


 


51
GGGCATGCTG TTTTACGCGC CGCAATGGTT GTGGGCTGCA TTTTGCGGAC


 


101
TGATTGCCCT GATTGCCTTG TGGGAATATG CCCGTATGGG CGGTTTGTGC


 


151
AAAATTAAAA CCAACCATTA CCTCGCCGCA ACCTTGGTTT TCGGCGTGGT


 


201
TGCCTATGCG GGCGGCTGGA TGCTGCCTAA TTTGGTTTGG TATGTTGTTT


 


251
TGGCATTTTG GCTCGCCGTT ATGCCTTTAT GGTTGAGATT CAAATGGAGG


 


301
CTCAACGGCG GTTGGCAGGT TTATGCCGTC GGCTGGCTTC TGGTCATGCC


 


351
GTTTTGGTTC GCGCTCGTAT CCCTGCGCCC GCATCCCGAT GATGCCCTGC


 


401
CGCTGCTCGC CGTGATGGGT TTGGTGTGGG TTGCCGATAT TTGCGCGTAT


 


451
TTCAGCGGCA AGGCGTTCGG CAAACACAAA ATCGCGCCGG CAATCAGCCC


 


501
CGGCAAAAGC TGGGAAGGTG CAATCGGCGG CGCGGTTTGC GTGGCAGTGT


 


551
ACATGACCGC CGTACGAAGT GCCGGCTGGC TGGCATTCGA TACAGGCTGG


 


601
TTCGATACCG TGTTAATCGG TTTGGTGCTG ACCGTTGTCA GCGTATGCGG


 


651
CGACCTTTTG GAAAGCTGGC TCAAGCGCGC GGCAGGCATC AAAGACAGCA


 


701
GCAAGCTGCT GCCCGGACAC GGCGGCGTGT TCGACCGTAC CGACAGCCTG


 


751
ATTGCCGTTA TCAGCGTCTA TGCAGCGATG ATGTCGGTTT TAAATTGA






This corresponds to the amino acid sequence <SEQ ID 1698; ORF 569>:










m569.pep..




1
MLKQRVITAM WLLPLMLGML FYAPQWLWAA FCGLIALIAL WEYARMGGLC


 


51
KIKTNHYLAA TLVFGVVAYA GGWMLPNLVW YVVLAFWLAV MPLWLRFKWR


 


101
LNGGWQVYAV GWLLVMPFWF ALVSLRPHPD DALPLLAVMG LVWVADICAY


 


151
FSGKAFGKHK IAPAISPGKS WEGAIGGAVC VAVYMTAVRS AGWLAFDTGW


 


201
FDTVLIGLVL TVVSVCGDLL ESWLKRAAGI KDSSKLLPGH GGVFDRTDSL


 


251
IAVISVYAAM MSVLN*






m569/g569 95.3% identity in 127 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1699>:










a569.seq




1
ATGCTGAAAC AACGGGTGAT AACCGCCATG TGGCTGCTGC CGCTGATGCT


 


51
GGGCATGCTG TTTTACGCGC CGCAATGGTT GTGGGCTGCA TTTTGCGGAC


 


101
TGATTGCCCT GATTGCCTTG TGGGAATATG CCCGTATGGG CGGTTTGTGC


 


151
AAAATTAAAA CCAACCATTA CCTCGCCGCA ACCTTGGTTT TCGGCGTGGT


 


201
TGCCTATGCG GGCGGCTGGA TGCTGCCTAA TTTGGTTTGG TATGTTGTTT


 


251
TGGCATTTTG GCTCGCCGTT ATGCCTTTAT GGTTGAGATT CAAATGGAGG


 


301
CTCAACGGCG GTTGGCAGGT TTATGCCGTC GGCTGGCTTC TGGTCATGCC


 


351
GTTTTGGTTC GCGCTCGTAT CCCTGCGCCC GCATCCCGAT GATGCCCTGC


 


401
CGCTGCTCGC CGTGATGGGT TTGGTGTGGG TTGCCGATAT TTGCGCGTAT


 


451
TTCAGCGGCA AGGCGTTCGG CAAACACAAA ATCGCACCGG CAATCAGCCC


 


501
CGGCAAAAGC TGGGAAGGTG CAATCGGCGG CGCGGTTTGC GTGGCCGTGT


 


551
ACATGACCGC CGTACGAAGT GCCGGCTGGC TGGCATTCGA TACAGGCTGG


 


601
TTCGATACCG TGTTAATCGG TTTGGTGTTG ACCGTTGTCA GCGTATGCGG


 


651
CGACCTTTTG GAAAGCTGGC TCAAGCGCGC GGCAGGCATC AAAGACAGCA


 


701
GCAACCTGCT GCCCGGACAC GGCGGCGTGT TCGACCGCAC CGACAGCCTG


 


751
ATTGCCGTTA TCAGCGTCTA TGCAGCGATG ATGTCGGTTT TAAATTGA






This corresponds to the amino acid sequence <SEQ ID 1700; ORF 569.a>:










a569.pep




1
MLKQRVITAM WLLPLMLGML FYAPQWLWAA FCGLIALIAL WEYARMGGLC


 


51
KIKTNHYLAA TLVFGVVAYA GGWMLPNLVW YVVLAFWLAV MPLWLRFKWR


 


101
LNGGWQVYAV GWLLVMPFWF ALVSLRPHPD DALPLLAVMG LVWVADICAY


 


151
FSGKAFGKHK IAPAISPGKS WEGAIGGAVC VAVYMTAVRS AGWLAFDTGW


 


201
FDTVLIGLVL TVVSVCGDLL ESWLKRAAGI KDSSNLLPGH GGVFDRTDSL


 


251
IAVISVYAAM MSVLN*






m569/a569 99.6% identity in 265 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1701>:










g570.seq..




1
atgatccgtt tgacccgcgc gtttgccgcc gccctgatcg gtttatgctg


 


51
caccacaggc gcgcacgccg acaccttcca aaaaatcggc tttatcaaca


 


101
ccgagcgcat ctacctcgaa tccaagcagg cgcgcaacat ccaaaaaacg


 


151
ctggacggcg aattttccgc ccgtcaggac gaattgcaaa aactgcaacg


 


201
cgaaggcttg gatttggaaa ggcagctcgc cggcggcaaa cttaaggacg


 


251
caaaaaaggc gcaagccgaa gaaaaatggc gcgggctggt cgaagcgttc


 


301
cgcaaaaaac aggcgcagtt tgaagaagac tacaacctcc gccgcaacga


 


351
agagtttgcc tccctccagc aaaacgccaa ccgcgtcatc gtcaaaatcg


 


401
ccaaacagga aggttacgat gtcattttgc aggacgtgat ttacgtcaac


 


451
acccaatacg acgttaccga cagcgtcatt aaagaaatga acgcccgctg


 


501
a






This corresponds to the amino acid sequence <SEQ ID 1702; ORF 570.ng>:










g570.pep..




1
MIRLTRAFAA ALIGLCCTTG AHADTFQKIG FINTERIYLE SKQARNIQKT


 


51
LDGEFSARQD ELQKLQREGL DLERQLAGGK LKDAKKAQAE EKWRGLVEAF


 


101
RKKQAQFEED YNLRRNEEFA SLQQNANRVI VKIAKQEGYD VILQDVIYVN


 


151
TQYDVTDSVI KEMNAR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1703>:










m570.seq..




1
ATGACCCGTT TGACCCGCGC GTTTGCCGCG GCTCTGATCG GTTTGTGCTG


 


51
CACCGCAGGC GCGCACGCCG ACACCTTCCA AAAAATCGGC TTTATCAACA


 


101
CCGAGCGCAT CTACCTCGAA TCCAAGCAGG CGCGCAAGAT TCAAAAAACG


 


151
CTGGACAGCG AATTTTCCGC TCGTCAGGAC GAATTGCAAA AACTGCAACG


 


201
CGAAGGTCTG GATTTGGAAA GGCAGCTTGC CGAAGGCAAA CTCAGAAACG


 


251
CAAAAAAGGC GCAAGCCGAA GAAAAATGGC GCGGGCTGGT CGCAGCGTTC


 


301
CGCAAAAAAC AGGCGCAGTT TGAAGAAGAC TACAACCTCC GCCGCAACGA


 


351
AGAGTTTGCC TCCCTCCAGC AAAACGCCAA CCGCGTCATC GTCAAAATCG


 


401
CCAAACAGGA AGGTTACGAT GTCATTTTGC AGAACGTGAT TTACGTCAAC


 


451
ACCCAATACG ACGTTACCGA CAGCGTCATT AAAGAAATGA ACGCCCGCTG


 


501
A






This corresponds to the amino acid sequence <SEQ ID 1704; ORF 570>:










m570.pep




1
MTRLTRAFAA ALIGLCCTAG AHADTFQKIG FINTERIYLE SKQARKIQKT


 


51
LDSEFSARQD ELQKLQREGL DLERQLAEGK LRNAKKAQAE EKWRGLVAAF


 


101
RKKQAQFEED YNLRRNEEFA SLQQNANRVI VKIAKQEGYD VILQNVIYVN


 


151
TQYDVTDSVI KEMNAR*






m570/g570 94.6% identity in 166 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1705>:










a570.seq




1
ATGACCCGTT TGACCCGCGC GTTTGCCGCG GCTCTGATCG GTTTGTGCTG


 


51
CACCGCAGGC GCGCACGCCG ACACCTTCCA AAAAATCGGC TTTATCAACA


 


101
CCGAGCGCAT CTACCTCGAA TCCAAGCAGG CGCGCAAGAT TCAAAAAACG


 


151
CTGGACAGCG AATTTTCCGC CCGCCAGGAC GAATTGCAAA AACTGCAACG


 


201
CGAAGGTCTG GATTTGGAAA GGCAGCTTGC CGAAGGCAAA CTCAAAGACG


 


251
CAAAAAAGGC GCAAGCCGAA GAAAAATGGT GCGGGCTGGT CGCAGCGTTC


 


301
CGCAAAAAAC AGGCGCAGTT TGAAGAAGAC TACAACCTCC GCCGCAACGA


 


351
AGAGTTTGCC TCCCTCCAGC AAAACGCCAA CCGCGTCATC GTCAAAATCG


 


401
CCAAACAGGA AGGTTACGAT GTCATTTTGC AGGACGTGAT TTACGTCAAC


 


451
ACCCAATACG ACGTTACCGA CAGCGTCATT AAAGAAATGA ACGCCCGCTG


 


501
A






This corresponds to the amino acid sequence <SEQ ID 1706; ORF 570.a>:










a570.pep




1
MTRLTRAFAA ALIGLCCTAG AHADTFQKIG FINTERIYLE SKQARKIQKT


 


51
LDSEFSARQD ELQKLQREGL DLERQLAEGK LKDAKKAQAE EKWCGLVAAF


 


101
RKKQAQFEED YNLRRNEEFA SLQQNANRVI VKIAKQEGYD VILQDVIYVN


 


151
TQYDVTDSVI KEMNAR*






m570/a570 97.6% identity in 166 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1707>:









g571.seq (partial)










1
atgcgcgttt tccgagtaaa ccgatttgtt gttaccgttt tcggcggcgg



 


51
tataggttct gccgtcccac acgctgcctg cgtcggcaaa caggctcagg


 


101
cggacggtgc gtgcgtcttt cgcaccgggc atcgggaaga gcagctcggc


 


151
ggagacgttg gcttttttgt tgccgccgta gctgattttt tcgccgtatt


 


201
cgtcatacac tttcgggccg agcgtgccgc tttcgtagcc gcgcaccgaa


 


251
cccaggccgc cgccgtagaa gttttcaaag aaggggattt ctttggttct


 


301
gccgtagccg cccgcaatgc cgacttcgcc gccgagcatc agcgtgaagg


 


351
ttttgct...






This corresponds to the amino acid sequence <SEQ ID 1708; ORF 571.ng>:









g571.pep (partial)










1
MRVFRVNRFV VTVFGGGIGS AVPHAACVGK QAQADGACVF RTGHREEQLG



 


51
GDVGFFVAAV ADFFAVFVIH FRAERAAFVA AHRTQAAAVE VFKEGDFFGS


 


101
AVAARNADFA AEHQREGFA...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1709>:










m571.seq




1
ATGGGTATTG CCGGCGCCGT AAATGTTTTG AACCCTGCCG CCGGTCGCGG


 


51
AACTGCTGTT GTCGTCGTAG GTTTTGCCGT CCCACACGCT GCCTGCGTCG


 


101
GCAAACAGGC TCAGGCGGAC GGTGCGCGCG TCTTTCGCGC CGGGCATCGG


 


151
GAAGAGCAGC TCGGCGGAGA CGTTGGCTTT TTTGTTGCCG CCGTAGCTGA


 


201
TTTTTTCGCC GTATTCGTCA TAGACTTTCG GACCGAGCGT GCCGCTTTCG


 


251
TATCCGCGCA CCGAACCCAG GCCGCCGCCG TAGAAGTTTT CAAAGAAGGG


 


301
GATTTCTTTG GTTCTGCCGT AGCCGCCCGC AATGCCGACT TCGCCGCCGA


 


351
GCATCAGCGT GAAGGTTTTG CTCAGGGGGA AGAACCAGGT TTGGTTGTGG


 


401
GTGGCGGAGT AGTATTGCAG TTTGCTGCCA GGCAGGGCGA TTTCGGCGTT


 


451
CACGCCCGTC AGGTAGCCGC GCGTCGGCCA TAA






This corresponds to the amino acid sequence <SEQ ID 1710; ORF 571>:










m571.pep




1
MGIAGAVNVL NPAAGRGTAV VVVGFAVPHA ACVGKQAQAD GARVFRAGHR


 


51
EEQLGGDVGF FVAAVADFFA VFVIDFRTER AAFVSAHRTQ AAAVEVFKEG


 


101
DFFGSAVAAR NADFAAEHQR EGFAQGEEPG LVVGGGVVLQ FAARQGDFGV


 


151
HARQVAARRP *






m571/g571 93.1% identity in 102 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1711>:










a571.seq




1
ATGGGTATTG CCGGCGCCGT AAATGTTTTG AACCCTGCCG CCGGTCGCGG


 


51
AACTGCTGTT GTCGTCGTAG GTTTTGCCGT CCCACACGCT GCCTGCGTCG


 


101
GCAAACAGGC TCAGGCGGAC GGTGCGCGCG TCTTTCGCGC CGGGCATCGG


 


151
GAAGAGCAGC TCGGCGGAGA CGTTGGCTTT TTTGTTGCCG CCGTAGCTGA


 


201
TTTTTTCGCC GTATTCGTCA TACACTTTCG GACCGAGCGT GCCGCTTTCG


 


251
TATCCGCGCA CCGAACCCAG GCCGCCGCCG TAGAAGTTTT CAAAGAAGGG


 


301
GATTTCTTTG GTTCTGCCGT AGCCGCCCGC AATGCCGACT TCGCCGCCGA


 


351
GCATCAGCGT GAAGGTTTTG CTTAAGGGGA AGAACCAGGT TTGGTTGTGG


 


401
GTGGCGGAGT AGTATTGCAG TTTGCTGCCG GGCAGGGCGA TTTCGGCGTT


 


451
CACGCCCGTC AGGTAGCCGC GCGTCGGCCA TAA






This corresponds to the amino acid sequence <SEQ ID 1712; ORF 571.a>:










a571.pep




1
MGIAGAVNVL NPAAGRGTAV VVVGFAVPHA ACVGKQAQAD GARVFRAGHR


 


51
EEQLGGDVGF FVAAVADFFA VFVIHFRTER AAFVSAHRTQ AAAVEVFKEG


 


101
DFFGSAVAAR NADFAAEHQR EGFA*GEEPG LVVGGGVVLQ FAAGQGDFGV


 


151
HARQVAARRP *






m571/a571 98.1% identity in 160 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1713>:










g572.seq..




1
atgtgcgcca tcgtcggggc ggcggggctg ccttccgcgc tcgcagcggc


 


51
gcaaaaaggc aaaaccattt atctggcaaa caaagaaacg ctggtggttt


 


101
ccggcgcgtt gtttatggaa accgcccgcg caaacggcgc ggcagtgttg


 


151
cccgtcgaca gcgaacacaa cgccattttc caagttttgc cgcgcgatta


 


201
cacagaccgt ctgaacgaac acggcatcga ttcgattatc ctgaccgctt


 


251
ccggcggccc gtttttaaca accgatttaa gcacgttcga cagcattacg


 


301
cccgagcagg cggtcaaaca ccccaattgg cgtatggggc gcaaaatctc


 


351
cgtcgattca gccactatgg caaacaaggg cttggaactg attgaagcgc


 


401
attggctgtt caactgtccg cccgacaaac tcgaagtcgt catccatccc


 


451
caatccgtga tacacagtat ggtgcgctac cgcgacggct ccgtgctggc


 


501
gcaactgggc aatcccgata tgcgaacgcc catcgcctat tgtttgggct


 


551
tgcccgagcg catcgattcg ggtgtcggca aactcgattt cggcgcattg


 


601
tccgcgctga ccttccaaaa gcccgacttc ggccgcttcc cctgcctgaa


 


651
gttcgcctat gaaaccataa acgcaggcgg agccgcgccc tgcgtattga


 


701
acgccgccaa cgaaaccgcc gtcgccgcct ttttggacgg acagattaag


 


751
tttaccgaca ttgccaaaac cgtcgcccac tgtcttgcac aagacttttc


 


801
aaacggcatg ggcgatatag aaggactgtt ggcgcaagat gcccggacac


 


851
gcgcacaagc gcgggcattt atcggcacac tgcgctga






This corresponds to the amino acid sequence <SEQ ID 1714; ORF 572.ng>:










g572.pep..




1
MCAIVGAAGL PSALAAAQKG KTIYLANKET LVVSGALFME TARANGAAVL


 


51
PVDSEHNAIF QVLPRDYTDR LNEHGIDSII LTASGGPFLT TDLSTFDSIT


 


101
PEQAVKHPNW RMGRKISVDS ATMANKGLEL IEAHWLFNCP PDKLEVVIHP


 


151
QSVIHSMVRY RDGSVLAQLG NPDMRTPIAY CLGLPERIDS GVGKLDFGAL


 


201
SALTFQKPDF GRFPCLKFAY ETINAGGAAP CVLNAANETA VAAFLDGQIK






The following partial DNA sequence was identified in N. meningitides <SEQ ID 1715>:










m572.seq..




1
ATGTGCGCCA TCGTCGGGGC GGTGGGGCTG CCTTCCGCGC TCGCAGCGGC


 


51
GCAAAAAGGC AAAACCATTT ATCTGGCAAA CAAAGAAACG CTGGTGGTTT


 


101
CCGGCGCGTT GTTTATGGAA ACCGCCCGTG CAAACGGCGC GGCAGTGCTG


 


151
CCCGTCGACA GCGAACACAA CGCCGTTTTC CAAGTTTTGC CGCGCGATTA


 


201
CGCCGGCCGT CTGAACGAAC ACGGCATCGC TTCGATTATC CTGACCGCTT


 


251
CCGGCGGCCC GTTTCTGACC GCCGATTTAA ACACGTTCGA CCGCATTACG


 


301
CCCGCCCAAG CGGTCAAACA CCCCAATTGG CGTATGGGAC GCAAAATCTC


 


351
CGTCGATTCC GCCACCATGA TGAACAAAGG TTTGGAGCTG ATTGAAGCGC


 


401
ATTGGCTGTT CAACTGTCCG CCCGACAAAC TCGAAGTCGT CATCCATCCG


 


451
CAATCCGTGA TACACAGCAT GGTGCGCTAC CGCGACGGCT CCGTGCTGGC


 


501
GCAACTGGGC AATCCCGATA TGCGAACGCC CATCGCTTAT TGTTTGGGTT


 


551
TGCCCGAGCG CATCGATTCG GGTGTCGGCG ACCTGGATTT CGACGCATTG


 


601
TCCGCGCTGA CCTTCCAAAA GCCCGACTTT GACCGCTTCC CCTGCCTGAG


 


651
GCTCGCCTAT GAAGCCATGA ACGCAGGCGG AGCCGCGCCC TGCGTATTGA


 


701
ACGCCGCCAA CGAAGCCGCC GTCGCCGCCT TTTTGGACGG ACAGATTAAG


 


751
TTTACCGACA TTGCCAAAAC CGTCGCCCAC TGTCTTGCAC AAGACTTTTC


 


801
AGACGGCATA GGCGATATAG GGGGGCTCTT GGCGCAAGAT GCCCGGACAC


 


851
GCGCACAAGC GCGAGCATTT ATCGGCACAC TGCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1716; ORF 572>:










m572.pep..




1
MCAIVGAVGL PSALAAAQKG KTIYLANKET LVVSGALFME TARANGAAVL


 


51
PVDSEHNAVF QVLPRDYAGR LNEHGIASII LTASGGPFLT ADLNTFDRIT


 


101
PAQAVKHPNW RMGRKISVDS ATMMNKGLEL IEAHWLFNCP PDKLEVVIHP


 


151
QSVIHSMVRY RDGSVLAQLG NPDMRTPIAY CLGLPERIDS GVGDLDFDAL


 


201
SALTFQKPDF DRFPCLRLAY EAMNAGGAAP CVLNAANEAA VAAFLDGQIK


 


251
FTDIAKTVAH CLAQDFSDGI GDIGGLLAQD ARTRAQARAF IGTLR*






m572/g572 92.9% identity in 295 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1717>:










a572.seq




1
ATGTGCGCCA TCGTCGGGGC GGTGGGGCTG CCTTCCGCGC TCGCAGCGGC


 


51
GCAAAAAGGC AAAACCATTT ATCTGGCGAA CAAAGAGACG CTGGTGGTTT


 


101
CCGGCGCGTT GTTTATGGAA ACCGCCCGTG CAAACGGCGC GGCAGTGCTG


 


151
CCCGTCGACA GCGAACACAA CGCCGTTTTC CAAGTTTTGC CGCGCGATTA


 


201
CACAGGTCGC CTGAACGAAC ACGGCATCGC TTCGATTATC CTGACCGCTT


 


251
CCGGCGGCCC GTTTCTGACC GCCGATTTAA ACACGTTCGA CAGCATTACG


 


301
CCCGACCAAG CGGTCAAACA CCCCAATTGG CGTATGGGAC GCAAAATCTC


 


351
CGTCGATTCC GCCACCATGA TGAACAAAGG TTTGGAGCTG ATTGAAGCGC


 


401
ATTGGCTGTT CAACTGTCCG CCCGACAAAC TCGAAGTCGT CATCCATCCG


 


451
CAATCTGTGA TACACAGCAT GGTGCGCTAC CGCGACGGCT CCGTGTTGGC


 


501
GCAACTGGGC AATCCCGATA TGCGAACGCC TATCGCTTAT TGTTTGGGTT


 


551
TGCCCGAGCG CATCGATTCG GGTGTCGGCG ACCTGGATTT CGACGCATTG


 


601
TCCGCGCTGA CCTTCCAAAA GCCCGACTTT GACCGCTTCC CCTGCCTGAA


 


651
GCTCGCCTAT GAAGCCATGA ACGCAGGCGG AGCCGCGCCC TGCGTATTGA


 


701
ACGCCGCCAA CGAAGCCGCC GTCGCCGCCT TTTTGGACGG ACAGATTAAG


 


751
TTTACCGACA TTGCCAAAAC CGTCGCCCAT TGTCTTTCAC AAGACTTTTC


 


801
AGACGGCATA GGCGACATAG GGGGGCTCTT GGCGCAAGAT GCCCGGACAC


 


851
GCGCACAAGC GCGGGCATTT ATCGGCACAC TGCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1718; ORF 572.a>:










a572.pep




1
MCAIVGAVGL PSALAAAQKG KTIYLANKET LVVSGALFME TARANGAAVL


 


51
PVDSEHNAVF QVLPRDYTGR LNEHGIASII LTASGGPFLT ADLNTFDSIT


 


101
PDQAVKHPNW RMGRKISVDS ATMMNKGLEL IEAHWLFNCP PDKLEVVIHP


 


151
QSVIHSMVRY RDGSVLAQLG NPDMRTPIAY CLGLPERIDS GVGDLDFDAL


 


201
SALTFQKPDF DRFPCLKLAY EAMNAGGAAP CVLNAANEAA VAAFLDGQIK


 


251
FTDIAKTVAH CLSQDFSDGI GDIGGLLAQD ARTRAQARAF IGTLR*






m572/a572 98.3% identity in 295 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1719>:










g573.seq..




1
atgccctgtt tgtgccgcct taatcgcaat atcggcagtt tccaaatcac


 


51
gaatctcacc gaccataatg atgtccgggt cctgacgcag gaaagacttc


 


101
aaagcagcgg caaaagtcag accctgctta tcattgacgt taacctgatt


 


151
gatgcccggc aggttaatct cggcagggtc ttccgccgtt gcaatattta


 


201
ccgactccgt attcaaaata ttcaaacagg tatagagcga caccgtctta


 


251
cccgaacccg tcggaccggt taccagcacc atcccgtaag gacggtgaat


 


301
cgcttccaac aacaattttt tctggaacgg ctcaaaaccg agctggtcga


 


351
tgttcaaaga cgcggcatcg gaattcaaaa tccgcatcac gaccttttcg


 


401
ccaaacagcg tcggcaatgt gctgacacgg aaatcgacag gcttgccgcc


 


451
cttttgaaag gtcagctgca tcctaccgtc ctgcggtatc cgtttttcgg


 


501
aaatgtccaa acgcgacatt accttaatcc gggaagcaag ctgccccctt


 


551
accgcaatgg gcggctgaac cacctcgcgg agctgcccgt ccacacggaa


 


601
acggatacgc gcattgtgtt cgtaaaactc gaaatggatg tcggatgccc


 


651
cgctacgcaa ggcatccgac aaagttttat ggataaacct cggaacaggg


 


701
ccgtcttctg cctcctcgtc gtcgatatac agggtgtggc tttcctcttc


 


751
ctcttgcccc tccccaagct cctgaagcag cgatgtcgaa cgcgaaccca


 


801
cccaatcgag caaacccgcc aactggtcat cctcgacaat gaccaactca


 


851
accgcaatcc ctgcggcaga aaccgttttc tgaatttgcg gcatctgggt


 


901
cggatcggaa accgcaaaaa atactttgtc gcccccacgg aaaaccggca


 


951
cacagtggaa ctccaccatc tgctcctccg tcaacacccc catcagcacc


 


1001
ctgtggcgcg gataatgacg caaatcaaga atcgaataac tgaacaccct


 


1051
cgcaatcaat gccgcaagcg acttgggcga aatgacaccg tctga






This corresponds to the amino acid sequence <SEQ ID 1720; ORF 573.ng>:










g573.pep..




1
MPCLCRLNRN IGSFQITNLT DHNDVRVLTQ ERLQSSGKSQ TLLIIDVNLI


 


51
DARQVNLGRV FRRCNIYRLR IQNIQTGIER HRLTRTRRTG YQHHPVRTVN


 


101
RFQQQFFLER LKTELVDVQR RGIGIQNPHH DLFAKQRRQC ADTEIDRLAA


 


151
LLKGQLHPTV LRYPFFGNVQ TRHYLNPGSK LPPYRNGRLN HLAELPVHTE


 


201
TDTRIVFVKL EMDVGCPATQ GIRQSFMDKP RNRAVFCLLV VDIQGVAFLF


 


251
LLPLPKLLKQ RCRTRTHPIE QTRQLVILDN DQLNRNPCGR NRFLNLRHLG


 


301
RIGNRKKYFV APTENRHTVE LHHLLLRQHP HQHPVARIMT QIKNRITEHP


 


351
RNQCRKRLGR NDTV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1721>:










m573.seq..




1
ATGCCCTGTT TGTGCCGCCT TAATCGCAAT ATCGGCAGTT TCCAAATCAC


 


51
GAATCTCACC GACCATAATG ATGTCCGGGT CCTGACGCAG GAAAGACTTC


 


101
AAAGCAGCGG CAAAAGTCAG GCCCTGCTTA TCATTGACGT TAACCTGATT


 


151
GATGCCCGGC AGGTTAATCT CGGCAGGGTC TTCCGCCGTT GCAATATTTA


 


201
CCGACTCCGT ATTCAAAATA TTCAAACAGG TATAGAGCGA CACCGTCTTA


 


251
CCCGAACCCG TCGGACCGGT TACCAGCACC ATCCCGTAGG GACGGTGAAT


 


301
CGCTACCAAC aCaw.TTTTT TCTGAAACGG CTCAAAACCG AGCTGGTCGA


 


351
TGTTCAAAGA CGCGGCATCG GAATTCAAAA TCCGCATCAC GACCTTTTCG


 


401
CCAAACAGCG TCGGCAATGT GCTGACACGG AAATCGACAG GCTTGCCGCC


 


451
CTTTTGAAAG GTCAGCTGCA TCCTGCCGTC CTGCGGTATC CGTTTTTCGG


 


501
AAATGTCCAA ACGCGACATT ACCTTAATCC GTGAAGCAAG CTGCCCCCTT


 


551
ACCGCAATGG GCGGCTGAAC CACCTCGCGG AGCTGCCCGT CCACACGGAA


 


601
ACGGATACGG GCATTGTGTT CGTAAAACTC GAAATGGATG TCCGATGCCC


 


651
CGCTGCGCAA GGCATCCGAC AAAGTCTTAT GGATAAACCT CGGAACAGGG


 


701
CCGTCTTCTG CCTCCTCGTT GTCGATATAC AGGGTGTGGC TTTCCTCTTC


 


751
CTCCTGCCCC TCCCCAAGCT CCTGAAGCAG CGATGTCGAA CGCGAACCCA


 


801
CCCAATCGAG CAAACCCGCC AACTGGTCAT CCTCGACAAT GACCAACTCA


 


851
ACCTCAATCC CTGCGGCAGA AACGGTTTTC TGAATTTGCG GCATCTGTGT


 


901
CGGATCGGAA ACCGCAAAAA ATACTTTGTC GCCCCGACGG AAAACCGGCA


 


951
CACAGTGGAA CTCCACCATC TGCTCCTCCG TCAACACCCC CATCAGCACC


 


1001
CTGTGGCGCG GATAATGACG CAAATCAAGA ATCGAATAAC TGAACACCCT


 


1051
CGCAATCAAT GCCGCAAGCG ACTTGGGCGA AATGACACCG TCTGA






This corresponds to the amino acid sequence <SEQ ID 1722; ORF 573>:










m573.pep..




1
MPCLCRLNRN IGSFQITNLT DHNDVRVLTQ ERLQSSGKSQ ALLIIDVNLI


 


51
DARQVNLGRV FRRCNIYRLR IQNIQTGIER HRLTRTRRTG YQHHPVGTVN


 


101
RYQHXFFLKR LKTELVDVQR RGIGIQNPHH DLFAKQRRQC ADTEIDRLAA


 


151
LLKGQLHPAV LRYPFFGNVQ TRHYLNP*SK LPPYRNGRLN HLAELPVHTE


 


201
TDTGIVFVKL EMDVRCPAAQ GIRQSLMDKP RNRAVFCLLV VDIQGVAFLF


 


251
LLPLPKLLKQ RCRTRTHPIE QTRQLVILDN DQLNLNPCGR NGFLNLRHLC


 


301
RIGNRKKYFV APTENRHTVE LHHLLLRQHP HQHPVARIMT QIKNRITEHP


 


351
RNQCRKRLGR NDTV*






m573/g573 95.9% identity in 364 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1723>:

a573.seq

    
    
        1 ATGCCCTGTT TGTGCCGCCT TAATCGCAAT ATCGGCAGTT TCCAAATCAC
        51 GAATCTCACC GACCATAATG ATGTCCGGGT CCTGACGCAG GAAAGACTTC
    
    











a573.seq




1
ATGCCCTGTT TGTGCCGCCT TAATCGCAAT ATCGGCAGTT TCCAAATCAC


 


51
GAATCTCACC GACCATAATG ATGTCCGGGT CCTGACGCAG GAAAGACTTC


 


101
AAAGCAGCGG CAAAAGTCAG ACCCTGCTTA TCATTGACGT TAACCTGATT


 


151
GATGCCCGGC AGGTTAATCT CGGCAGGGTC TTCCGCCGTT GCAATATTTA


 


201
CCGACTCCGT ATTCAAAATA TTCAAACAGG TATAGAGCGA CACCGTCTTA


 


251
CCCGAACCCG TCGGACCGGT TACCAGCACC ATCCCGTAGG GACGGTGAAT


 


301
CGCTTCCAAC AACAATTTTT TCTGAAACGG CTCAAAACCG AGCTGGTCGA


 


351
TGTTCAAAGA CGCGGCATCG GAATTCAAAA TCCGCATCAC GACCTTTTCG


 


401
CCAAACAGCG TCGGCAATGT GCTGACACGG AAATCGACAG GCTTGCCGCC


 


451
CTTTTGAAAG GTCAGCTGCA TCCTGCCGTC CTGCGGTATC CGTTTTTCGG


 


501
AAATGTCCAA ACGCGACATT ACCTTAATCC GGGAAGCAAG CTGCCCCCTT


 


551
ACCGCAATGG GCGGCTGAAC CACCTCGCGG AGCTGCCCGT CCACACGGAA


 


601
ACGGATACGG GCATTGTGTT CGTAAAACTC GAAATGGATG TCCGATGCCC


 


651
CGCTGCGCAA GGCATCCGAC AAAGTCTTAT GGATAAACCT CGGAACAGGG


 


701
CCGTCTTCTG CCTCCTCGTT GTCGATATAC AGGGTGTGGC TTTCCTCTTC


 


751
CTCCTGCCCC TCCCCAAGCT CCTGAAGCAG CGATGTCGAA CGCGAACCCA


 


801
CCCAATCGAG CAAACCCGCC AACTGGTCAT CCTCGACAAT GACCAACTCA


 


851
ACCTCAATCC CTGCGGCAGA AACGGTTTTC TGAATTTGCG GCATCTGTGT


 


901
CGGATCGGAA ACCGCAAAAA ATACTTTGTC GCCCCGACGG AAAACCGGCA


 


951
CACAGTGGAA CTCCACCATC TGCTCCTCCG TCAACACCCC CATCAGCACC


 


1001
CTGTGGCGCG GATAATGACG CAAATCAAGA ATCGAATAAC TGAACACCCT


 


1051
CGCAATCAAT GCCGCAAGCG ACTTGGGCGA AATGACACCG TCTGA






This corresponds to the amino acid sequence <SEQ ID 1724; ORF 573.a>:










a573.pep




1
MPCLCRLNRN IGSFQITNLT DHNDVRVLTQ ERLQSSGKSQ TLLIIDVNLI


 


51
DARQVNLGRV FRRCNIYRLR IQNIQTGIER HRLTRTRRTG YQHHPVGTVN


 


101
RFQQQFFLKR LKTELVDVQR RGIGIQNPHH DLFAKQRRQC ADTEIDRLAA


 


151
LLKGQLHPAV LRYPFFGNVQ TRHYLNPGSK LPPYRNGRLN HLAELPVHTE


 


201
TDTGIVFVKL EMDVRCPAAQ GIRQSLMDKP RNRAVFCLLV VDIQGVAFLF


 


251
LLPLPKLLKQ RCRTRTHPIE QTRQLVILDN DQLNLNPCGR NGFLNLRHLC


 


301
RIGNRKKYFV APTENRHTVE LHHLLLRQHP HQHPVARIMT QIKNRITEHP


 


351
RNQCRKRLGR NDTV*






m573/a573 98.6% identity in 364 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1725>:










g574.seq




1
atgctgccga atctgccaaa cagccttaag aaagccgata tggacaacga


 


51
attgtggatt atcctgctgc cgattatcct tttgcccgtc ttcttcacga


 


101
tgggctggtt tgccgcccgc gtggatatga aaaccgtatt gaagcaggca


 


151
aaaagcatcc cttcgggatt ttataaaagc ctggacgctt tggtcgaccg


 


201
caacagcggg cgcgcggcaa gggagttggc ggaagtcgtc gacggccggc


 


251
cgcaatcgta tgatttgaac cttaccctcg gcaaacttta ccgtcagcgc


 


301
ggcgaaaacg acaaagccat caacatacac cggacaatgc tcgattctcc


 


351
cgatacggtc ggcgaaaagc gcgcgcgcgt cctgtttgaa ttggcgcaaa


 


401
actaccaaag cgcgggtttg gtcgatcgtg ccgaacagat ttttttgggg


 


451
ctgcaagacg gtgaaatggc gcgtgaagcc agacagcacc tgctcaatat


 


501
ctaccagcag gacagggatt gggaaaaagc ggttgaaacc gcccaacttc


 


551
ttagtcacga cgaacagaca tatcagtttg agattgcaca gttttattgc


 


601
gaacttgccc aagccgcgct gttcaagtcc aatttcgatg ccgcgcgttt


 


651
caatgtcggc aaggcactcg aagccaacaa aaaatgcacc cgcgccaaca


 


701
tgattttggg cgacattgaa caccgacaag gcaatttccc tgccgccgtc


 


751
gaagcctatg ccgccatcga gcagcaaaac catgcatact tgagcatggt


 


801
cggcgagaag ctttacgaag cctatgccgc gcagggaaaa cctgaagaag


 


851
gcttgaaccg tctgacagga tatatgcaga cgtttcccga acttgacctg


 


901
atcaatgtcg tgtacgagaa atccctgctg cttaagggcg agaaagaagc


 


951
cgcgcaaacc gccgtcgagc ttgtccgccg caagcccgac cttaacggcg


 


1001
tgtaccgcct gctcggtttg aaactcagcg atttggatcc ggcttggaaa


 


1051
gccgatgccg acatgatgcg ttcggttatc ggacggcagc tccagcgcag


 


1101
cgtgatgtac cgttgccgca actgccactt caaatcccaa gtctttttct


 


1151
ggcactgtcc cgcctgcaac aaatggcaga cgtttacgcc gaataaaatc


 


1201
gaagtttaa






This corresponds to the amino acid sequence <SEQ ID 1726; ORF 574.ng>:










g574.pep..




1
MLPNLPNSLK KADMDNELWI ILLPIILLPV FFTMGWFAAR VDMKTVLKQA


 


51
KSIPSGFYKS LDALVDRNSG RAARELAEVV DGRPQSYDLN LTLGKLYRQR


 


101
GENDKAINIH RTMLDSPDTV GEKRARVLFE LAQNYQSAGL VDRAEQIFLG


 


151
LQDGEMAREA RQHLLNIYQQ DRDWEKAVET AQLLSHDEQT YQFEIAQFYC


 


201
ELAQAALFKS NFDAARFNVG KALEANKKCT RANMILGDIE HRQGNFPAAV


 


251
EAYAAIEQQN HAYLSMVGEK LYEAYAAQGK PEEGLNRLTG YMQTFPELDL


 


301
INVVYEKSLL LKGEKEAAQT AVELVRRKPD LNGVYRLLGL KLSDLDPAWK


 


351
ADADMMRSVI GRQLQRSVMY RCRNCHFKSQ VFFWHCPACN KWQTFTPNKI


 


401
EV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1727>:










m574.seq..




1
ATGCGCCCGA ATCTACCAAA CAGCCTTAAG AAAGCCGATA TGGACAACGA


 


51
ATTGTGGATT ATCCTGCTGC CGATTATCCT TTTGCCCGTC TTCTTCGCGA


 


101
TGGGCTGGTT TGCCGCCCGC GTGGATATGA AAACCGTATT GAAGCAGGCA


 


151
AAAAGCATCC CTTCGGGATT TTATAAAAGC TTGGACGCTT TGGTCGACCG


 


201
CAACAGCGGG CGCGCGGCAA GGGAGTTGGC GGAAGTCGTC GACGGCCGGC


 


251
CGCAATCGTA TGATTTGAAC CTCACCCTCG GCAAACTTTA CCGCCAGCGT


 


301
GGCGAAAACG ACAAAGCCAT CAACATACAC CGGACAATGC TCGATTCTCC


 


351
CGATACGGTC GGCGAAAAGC GCGCGCGCGT CCTGTTTGAA TTGGCGCAAA


 


401
ACTACCAAAG TGCGGGGTTG GTCGATCGTG CCGAACAGAT TTTTTTGGGG


 


451
CTGCAAGACG GTAAAATGGC GCGTGAAGCC AGACAGCACC TGCTCAATAT


 


501
CTACCAACAG GACAGGGATT GGGAAAAAGC GGTTGAAACC GCCCGGCTGC


 


551
TCAGCCATGA CGATCAGACC TATCAGTTTG AAATCGCCCA GTTTTATTGC


 


601
GAACTTGCCC AAGCCGCGCT GTTCAAGTCC AATTTCGATG TCGCGCGTTT


 


651
CAATGTCGGC AAGGCACTCG AAGCCAACAA AAAATGCACC CGCGCCAACA


 


701
TGATTTTGGG CGACATCGAA CACCGACAAG GCAATTTCCC TGCCGCCGTC


 


751
GAAGCCTATG CCGCCATCGA GCAGCAAAAC CATGCATACT TGAGCATGGT


 


801
CGGCGAGAAG CTTTACGAAG CCTATGCCGC GCAGGGAAAA CCTGAAGAAG


 


851
GCTTGAACCG TCTGACAGGA TATATGCAGA CGTTTCCCGA ACTTGACCTG


 


901
ATCAATGTCG TGTACGAGAA ATCCCTGCTG CTTAAGTGCG AGAAAGAAGC


 


951
CGCGCAAACC GCCGTCGAGC TTGTCCGCCG CAAGCCCGAC CTTAACGGCG


 


1001
TGTACCGCCT GCTCGGTTTG AAACTCAGCG ATATGAATCC GGCTTGGAAA


 


1051
GCCGATGCCG ACATGATGCG TTCGGTTATC GGACGGCAGC TACAGCGCAG


 


1101
CGTGATGTAC CGTTGCCGCA ACTGCCACTT CAAATCCCAA GTCTTTTTCT


 


1151
GGCACTGCCC CGCCTGCAAC AAATGGCAGA CGTTTACCCC GAATAAAATC


 


1201
GAAGTTTAA






This corresponds to the amino acid sequence <SEQ ID 1728; ORF 574>:










m574.pep..




1
MRPNLPNSLK KADMDNELWI ILLPIILLPV FFAMGWFAAR VDMKTVLKQA


 


51
KSIPSGFYKS LDALVDRNSG RAARELAEVV DGRPQSYDLN LTLGKLYRQR


 


101
GENDKAINIH RTMLDSPDTV GEKRARVLFE LAQNYQSAGL VDRAEQIFLG


 


151
LQDGKMAREA RQHLLNIYQQ DRDWEKAVET ARLLSHDDQT YQFEIAQFYC


 


201
ELAQAALFKS NFDVARFNVG KALEANKKCT RANMILGDIE HRQGNFPAAV


 


251
EAYAAIEQQN HAYLSMVGEK LYEAYAAQGK PEEGLNRLTG YMQTFPELDL


 


301
INVVYEKSLL LKCEKEAAQT AVELVRRKPD LNGVYRLLGL KLSDMNPAWK


 


351
ADADMMRSVI GRQLQRSVMY RCRNCHFKSQ VFFWHCPACN KWQTFTPNKI


 


401
EV*






m573/g573 97.8% identity in 402 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1729>:










a574.seq




1
ATGCGCCCGA ATCTGCCAAA CAGCCTTGAG AAAGCCGATA TGGACAATGA


 


51
ATTGTGGATT ATCCTGCTGC CGATTATCCT TTTGCCCGTT TTCTTCGCGA


 


101
TGGGCTGGTT TGCCGCCCGC GTGGATATGA AGACTGTATT AAAGCAGGCA


 


151
AAAAGCATAC CGTCGGGATT TTATAAAAGT CTGGATGCCT TGGTTGACCG


 


201
CAACAGCGGG CGCGCGGCAA GGGAGTTGGC GGAAGTCGTC GACGGCCGGC


 


251
CGCAATCGTA TGATTTGAAC CTCACCCTCG GCAAACTTTA CCGCCAGCGT


 


301
GGCGAAAACG ACAAAGCCAT CAATATGCAC CAAACATTGC TTGACTCTCC


 


351
CGATACAACC GGAGCCAAGC GCGCGCGCGT CCTGTTTGAA TTGGCGCAAA


 


401
ACTACCAAAG TGCGGGGTTG GTCGATCGTG CCGAACAGAT TTTTTTGGGG


 


451
CTGCAAGACG GTGAAATGGC GCGTGAAGCC AGACAGCACC TGCTCAATAT


 


501
CTACCAACAG GACAGGGATT GGGAAAAAGC GGTTGAAACC GCCCGGCTGC


 


551
TCAGCCATGA CGATCAGACC TATCAGTTTG AAATCGCCCA GTTTTATTGC


 


601
GAACTTGCCC AAGCCGCGCT GTTCAAGTCC AATTTCGATG CCGCGCGTTT


 


651
CAATGTCGGC AAGGCACTCG AAGCCAACAA AAAATGCACC CGCGCCAACA


 


701
TGATTTTGGG CGACATCGAA CACCGACAAG GCAATTTCCC TGCCGCCGTC


 


751
GAAGCCTATG CCGCCATCGA GCAGCAAAAC CATGCATACT TGAGTATGGT


 


801
CGGCGAGAAG CTTTACGAAG CCTATGCCGC GCAGGGAAAA CCTGAAGAAG


 


851
GCTTGAACCG TCTGACAGGA TATATGCAGA CGTTTCCCGA ACTTGACCTG


 


901
ATCAATGTCG TGTACGAGAA ATCCCTGCTG CTTAAGTGCG AGAAAGAAGC


 


951
CGCGCAAACC GCCGTCGAGC TTGTCCGCCG CAAGCCCGAC CTCAACGGCG


 


1001
TGTACCGCCT GCTTGGTTTG AAACTCAGCG ATTTGGATCC GGCTTGGAAA


 


1051
GCCGATGCCG ATATGATGCG TTCGGTTATC GGACGGCAGC TACAGCGCAG


 


1101
CGTGATGTAC CGGTGCCGAA ACTGCCACTT CAAATCACAA GTCTTTTTCT


 


1151
GGCATTGTCC TGCCTGCAAC AAATGGCAGA CGTTTACGCC AAACAAAATC


 


1201
GAAGTTTAA






This corresponds to the amino acid sequence <SEQ ID 1730; ORF 574.a>:










a574.pep




1
MRPNLPNSLE KADMDNELWI ILLPIILLPV FFAMGWFAAR VDMKTVLKQA


 


51
KSIPSGFYKS LDALVDRNSG RAARELAEVV DGRPQSYDLN LTLGKLYRQR


 


101
GENDKAINMH QTLLDSPDTT GAKRARVLFE LAQNYQSAGL VDRAEQIFLG


 


151
LQDGEMAREA RQHLLNIYQQ DRDWEKAVET ARLLSHDDQT YQFEIAQFYC


 


201
ELAQAALFKS NFDAARFNVG KALEANKKCT RANMILGDIE HRQGNFPAAV


 


251
EAYAAIEQQN HAYLSMVGEK LYEAYAAQGK PEEGLNRLTG YMQTFPELDL


 


301
INVVYEKSLL LKCEKEAAQT AVELVRRKPD LNGVYRLLGL KLSDLDPAWK


 


351
ADADMMRSVI GRQLQRSVMY RCRNCHFKSQ VFFWHCPACN KWQTFTPNKI


 


401
EV*






m574/a574 97.5% identity in 402 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1731>:









g575.seq (partial)










1
..atgccgtgcc tccgccggca agcagcaagg tgtacgaacc gccgaacaga



 


51
  ccgtcaaaca gtccgctttc ggtttcttct tcggcagaaa cctgttcgac


 


101
  aggttcggca acgggttcgg cggcaacttc actggctgtt tccgcaacag


 


151
  gttcggaaac ggtgttaccg gtttcgtcgg tcggcgtgtc gatggcagaa


 


201
  gcggcggctt cttggggggg cggattcggc agcggtttcc gatgcggcag


 


251
  tatttgcagc gggtacaggt ccgggttggc gttctgtcgc cgaagccgga


 


301
  gtttcggaca ctgcgggttt gggttcgggt cgaacggccg gtttttccgc


 


351
  ttttgcttcg ggcgcggcaa cttttgcttc aggtttttca accggttttt


 


401
  cgacaggttt ctctatcggt ttctccacag ttgcctgttt ggacggttca


 


451
  gacggcatgg atgcagtttc ggctttgggt ttcgccgttt gcggtttggg


 


501
  ttgttccgct ttgatttttt tgggtgctgc cgctttgatc ctgttcagat


 


551
  tcggaatgtg a*






This corresponds to the amino acid sequence <SEQ ID 1732; ORF 575.ng>:









g575.pep (partial)










1
..MPCLRRQAAR CTNRRTDRQT VRFRFLLRQK PVRQVRQRVR RQLHWLFPQQ



 


51
  VRKRCYRFRR SACRWQKRRL LGGADSAAVS DAAVFAAGTG PGWRSVAEAG


 


101
  VSDTAGLGSG RTAGFSAFAS GAATFASGFS TGFSTGFSIG FSTVACLDGS


 


151
  DGMDAVSALG FAVCGLGCSA LIFLGAAALI LFRFGM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1733>:










m575.seq..




1
ATGGTTTCGG GCGAGGAAGC CTTCAGGAAG CCTGCCAGTC CGGAGGGTGA


 


51
GGCAGGTTTT GCGGAAGCTG TTTCTTCTGT GCCGATATGG TTGTTTGAGG


 


101
GCAGGTTGTC GGAGAAATCG GTATCGACGG TTTCCGGTTT GTTTTCGGCA


 


151
GTTTGGGCGA CAGATTCCGG TTCGGGCGTG TCGATGACGA TTTCGACAGG


 


201
GTTGTACGGG TTGAAGGTCT CGGGCTCGTA CACGCTGTCT GTGGATTCGA


 


251
TGGCGTTCCA ATCGGCATCC GCGCGTTTTT GGGTTTCTTC ATCCTGCGTA


 


301
AGTGCGCCGG ATAAAATGCC GTTTTGCGCG GCTGCCAGGC TGTCGAAATC


 


351
CAAGTCGATG CGGTTGGAAG GCGTATCGGT TTCGACATCG AACGTTTGTT


 


401
TTGCCGATAA CTCTTCTTCA GATTCCCCAT CTAAGGCAAG TGTGTCGTTT


 


451
ACATCGTTTT TCGGAGCGGG TTCGGGCGTT GCCGGAGTTT CGACTTCGGC


 


501
AAAGGTGATT TCTATGCCGT CGTCTGCCGC GTCGTCAAGG TCAGGCTCTT


 


551
CCTCAGGGAC GGATTCTTCG GTACGGCGCG CGCGTTTGGA TTGGGCAAGG


 


601
CGCAAAAGCA GCAGCAGGGC GATTAATGCC GCGCCTCCGC CGGCAAGCAG


 


651
CAAGGTGTAC GAACCGCCGA ACAGACCGTC AAACAGTCCG CTTTCGGTTT


 


701
CTTCTTCGGC AGAAACCTGT TCGACAGGTT CGGAAACGGC GTTACCGGTT


 


751
TCGTCGGTCG GCGTGTCGAT GGCAGAAGCG GCGGCTTCTT GGGGGGCGGA


 


801
TTCGGCAGCG GTTTCCGATG CGGCAGTATT TGCAGCGGGT ACAGGTTCGG


 


851
GTCGAACGGC CGGTTTTTCC GCTTTTGCTT CGGGCGCGGC AACTTTTGCT


 


901
TCAGGTTTTT CAACCGGTTT CTCTACCGTT GCCTGTTTGG ACGGTTCGGA


 


951
CGGCATGGAT GCGGTTTCGG CTTTGGGTTT CGCCGTTTGC GGTTTGGGTT


 


1001
GTTCCGCTTT GATCCTGTTC AGATTCGGAA TGTGA






This corresponds to the amino acid sequence <SEQ ID 1734; ORF 575>:










m575.pep




1
MVSGEEAFRK PASPEGEAGF AEAVSSVPIW LFEGRLSEKS VSTVSGLFSA



 


51
VWATDSGSGV SMTISTGLYG LKVSGSYTLS VDSMAFQSAS ARFWVSSSCV


 


101
SAPDKMPFCA AARLSKSKSM RLEGVSVSTS NVCFADNSSS DSPSKASVSF


 


151
TSFFGAGSGV AGVSTSAKVI SMPSSAASSR SGSSSGTDSS VRRARLDWAR


 


201
RKSSSRAINA APPPASSKVY EPPNRPSNSP LSVSSSAETC STGSETALPV


 


251
SSVGVSMAEA AASWGADSAA VSDAAVFAAG TGSGRTAGFS AFASGAATFA


 


301
SGFSTGFSTV ACLDGSDGMD AVSALGFAVC GLGCSALILF RFGM*






m575/g575 70.2% identity in 114 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1735>:










a575.seq




1
ATGGTTTCGG GCGAGGAAGC CTTCAGGAAG CCTGCCAGTC CGGAGGGTGA



 


51
GGCAGGTTTT GCGGAAGCTG TTTCTTCTGT GCCGATATGG TTGTTTGAGG


 


101
GCAGGTTGTC GGAGAAATCG GTATCGACGG TTTCCGGTTT GTTTTCGGCA


 


151
GTTTGGGCGA CAGATTCCGG TTCGGGCGTG TCGATGACGA TTTCGACAGG


 


201
GTTGTACGGG TTGAAGGTCT CGGGCTCGTA CACGCTGTCT GTGGATTCGA


 


251
TGGCGTTCCA ATCGGCATCC GCGCGTTTTT GGGTTTCTTC ATCCTGCGTA


 


301
AGTGCGCCGG ATAAAATGCC GTTTTGCGCG GCTGCCAGGC TGTCGAAATC


 


351
CAAGTCGATG CGGTTGGAAG GCGTATCGGT TTCGACATCG AACGTTTGTT


 


401
TTGCCGACAA CTCTTCTTCA GATTCCCCAT CTAAGGCAAG TGTGTCGTTT


 


451
ACATCGTTTT TCGGAGCGGG TTCGGGCGTT GCCGGAGTTT CGACTTCGGC


 


501
AAAGGTGATT TCTATGCCGT CGTCTGCCGC GTCGTCAAGG TCAGGCTCTT


 


551
CCTCAGGGAC GGATTCTTCG GTACGGCGCG CGCGTTTGGA TTGGGCAAGG


 


601
CGCAAAAGCA GCAGCAGGGC GATCAATGCC GCGCCTCCGC CGGCAAGCAG


 


651
CAAGGTGTAC GAACCGCCGA ACAGTCCGCT TTCGGTTTCT TCTTCGGCAG


 


701
AAACCTGTTC GACAGGTTCG GAAACGGCGT TACCGGTTTC GTCGGTCGGC


 


751
GTGTCGATGG CAGAAGCGGC GGCTTCTTGG GGGGCGGATT CGGCAGCGGT


 


801
TTCCGATGCG GCAGTATTTG CAGCGGGTAC AGGTTCGGGT CGAACGGCCG


 


851
GTTTTTCCGC TTTTGCTTCG GGCGCGGCAA CTTTTGCTTC AGGTTTTTCA


 


901
ACCGGTTTCT CTACCGTTGC CTGTTTGGAC GGTTCGGACG GCATGGATGC


 


951
GGTTTCGGCT TTGGGTTTCG CCGTTTGCGG TTTGGGTTGT TCCGCTTTGA


 


1001
TCCTGTTCAG ATTCGGAATG TGA






This corresponds to the amino acid sequence <SEQ ID 1736; ORF 575.a>:










a575.pep




1
MVSGEEAFRK PASPEGEAGF AEAVSSVPIW LFEGRLSEKS VSTVSGLFSA



 


51
VWATDSGSGV SMTISTGLYG LKVSGSYTLS VDSMAFQSAS ARFWVSSSCV


 


101
SAPDKMPFCA AARLSKSKSM RLEGVSVSTS NVCFADNSSS DSPSKASVSF


 


151
TSFFGAGSGV AGVSTSAKVI SMPSSAASSR SGSSSGTDSS VRRARLDWAR


 


201
RKSSSRAINA APPPASSKVY EPPNSPLSVS SSAETCSTGS ETALPVSSVG


 


251
VSMAEAAASW GADSAAVSDA AVFAAGTGSG RTAGFSAFAS GAATFASGFS


 


301
TGFSTVACLD GSDGMDAVSA LGFAVCGLGC SALILFRFGM *






m575/a575 98.8% identity in 344 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1737>:









g576.seq.. (partial)










1
..atgggcgtgg acatcggacg ctccctgaaa caaatgaagg aacagggcgc



 


51
  ggaaatcgat ttgaaagtct ttaccgatgc catgcaggca gtgtatgacg


 


101
  gcaaagaaat caaaatgacc gaagagcagg cccaggaagt gatgatgaaa


 


151
  ttcctgcagg agcagcaggc taaagccgta gaaaaacaca aggcggatgc


 


201
  gaaggccaac aaagaaaaag gcgaagcctt cctgaaggaa aatgccgccg


 


251
  aagacggcgt gaagaccact gcttccggtc tgcagtacaa aatcaccaaa


 


301
  cagggtgaag gcaaacagcc gacaaaagac gacatcgtta ccgtggaata


 


351
  cgaaggccgc ctgattgacg gtaccgtatt cgacagcagc aaagccaacg


 


401
  gcggcccggc caccttccct ttgagccaag tgattccggg ttggaccgaa


 


451
  ggcgtacggc ttctgaaaga aggcggcgaa gccacgttct acatcccgtc


 


501
  caaccttgcc taccgcgaac agggtgcggg cgaaaaaatc ggtccgaacg


 


551
  ccactttggt atttgacgtg aaactggtca aaatcggcgc acccgaaaac


 


601
  gcgcccgcca agcagccgga tcaagtcgac atcaaaaaag taaattaa






This corresponds to the amino acid sequence <SEQ ID 1738; ORF 576.ng>:









g576.pep.. (partial)










1
..MGVDIGRSLK QMKEQGAEID LKVFTDAMQA VYDGKEIKMT EEQAQEVMMK



 


51
  FLQEQQAKAV EKHKADAKAN KEKGEAFLKE NAAEDGVKTT ASGLQYKITK


 


101
  QGEGKQPTKD DIVTVEYEGR LIDGTVFDSS KANGGPATFP LSQVIPGWTE


 


151
  GVRLLKEGGE ATFYIPSNLA YREQGAGEKI GPNATLVFDV KLVKIGAPEN


 


201
  APAKQPDQVD IKKVN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1739>:









m576.seq.. (partial)










1
..ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA



 


51
  GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


101
  CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


151
  GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


201
  AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


251
  TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


301
  CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


351
  CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


401
  TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


451
  GTGATTCCGG GTTGGACCGA AGgCGTACAG CTTCTGAAAG AAGGCGGCGA


 


501
  AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


551
  GCGACAAAAT CGGTCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


601
  AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


651
  CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 1740; ORF 576>:









m576.pep.. (partial)










1
..MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ



 


51
  AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


101
  LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


151
  VIPGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


201
  KIGAPENAPA KQPAQVDIKK VN*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m576/g576 97.2% identity in 215 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1741>:










a576.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC



 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTTCCGCG CAGGGCGACA CCTCTTCGAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


401
TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


451
CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


601
GTGATTCTGG GTTGGACCGA AGGCGTACAG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGACAAAAT CGGCCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 1742; ORF 576.a>:










a576.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASSA QGDTSSIGST



 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


201
VILGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPAQVDIKK VN*






m576/a576 99.5% identity in 222 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1743>:










g576-1.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC



 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTGCCGCG CAGGGCGACA CCTCTTCAAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC AATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
ACAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGATG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCCCAGGAAG TGATGATGAA ATTCCTGCAG GAGCAGCAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGATG CGAAGGCCAA CAAAGAAAAA GGCGAAGCCT


 


401
TCCTGAAGGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGT


 


451
CTGCAGTACA AAATCACCAA ACAGGGTGAA GGCAAACAGC CGACAAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACCGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG CCACCTTCCC TTTGAGCCAA


 


601
GTGATTCCGG GTTGGACCGA AGGCGTACGG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGAAAAAAT CGGTCCGAAC GCCACTTTGG TATTTGACGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG ATCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 1744; ORF 576-1.ng>:










g576-1.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASAA QGDTSSIGST



 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTDAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPATFPLSQ


 


201
VIPGWTEGVR LLKEGGEATF YIPSNLAYRE QGAGEKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPDQVDIKK VN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1745>:










m576-1.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC



 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTTCCGCG CAGGGCGACA CCTCTTCGAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


401
TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


451
CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


601
GTGATTCCGG GTTGGACCGA AGGCGTACAG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGACAAAAT CGGTCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 1746; ORF 576-1>:










m576-1.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASSA QGDTSSIGST



 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


201
VIPGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPAQVDIKK VN*






g576-1/m576-1 97.8% identity in 272 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1747>:










a576-1.seq




1
ATGAACACCA TTTTCAAAAT CAGCGCACTG ACCCTTTCCG CCGCTTTGGC



 


51
ACTTTCCGCC TGCGGCAAAA AAGAAGCCGC CCCCGCATCT GCATCCGAAC


 


101
CTGCCGCCGC TTCTTCCGCG CAGGGCGACA CCTCTTCGAT CGGCAGCACG


 


151
ATGCAGCAGG CAAGCTATGC GATGGGCGTG GACATCGGAC GCTCCCTGAA


 


201
GCAAATGAAG GAACAGGGCG CGGAAATCGA TTTGAAAGTC TTTACCGAAG


 


251
CCATGCAGGC AGTGTATGAC GGCAAAGAAA TCAAAATGAC CGAAGAGCAG


 


301
GCTCAGGAAG TCATGATGAA ATTCCTTCAG GAACAACAGG CTAAAGCCGT


 


351
AGAAAAACAC AAGGCGGACG CGAAGGCCAA TAAAGAAAAA GGCGAAGCCT


 


401
TTCTGAAAGA AAATGCCGCC AAAGACGGCG TGAAGACCAC TGCTTCCGGC


 


451
CTGCAATACA AAATCACCAA ACAGGGCGAA GGCAAACAGC CGACCAAAGA


 


501
CGACATCGTT ACCGTGGAAT ACGAAGGCCG CCTGATTGAC GGTACGGTAT


 


551
TCGACAGCAG CAAAGCCAAC GGCGGCCCGG TCACCTTCCC TTTGAGCCAA


 


601
GTGATTCTGG GTTGGACCGA AGGCGTACAG CTTCTGAAAG AAGGCGGCGA


 


651
AGCCACGTTC TACATCCCGT CCAACCTTGC CTACCGCGAA CAGGGTGCGG


 


701
GCGACAAAAT CGGCCCGAAC GCCACTTTGG TATTTGATGT GAAACTGGTC


 


751
AAAATCGGCG CACCCGAAAA CGCGCCCGCC AAGCAGCCGG CTCAAGTCGA


 


801
CATCAAAAAA GTAAATTAA






This corresponds to the amino acid sequence <SEQ ID 1748; ORF 576-1.a>:










a576-1.pep




1
MNTIFKISAL TLSAALALSA CGKKEAAPAS ASEPAAASSA QGDTSSIGST



 


51
MQQASYAMGV DIGRSLKQMK EQGAEIDLKV FTEAMQAVYD GKEIKMTEEQ


 


101
AQEVMMKFLQ EQQAKAVEKH KADAKANKEK GEAFLKENAA KDGVKTTASG


 


151
LQYKITKQGE GKQPTKDDIV TVEYEGRLID GTVFDSSKAN GGPVTFPLSQ


 


201
VILGWTEGVQ LLKEGGEATF YIPSNLAYRE QGAGDKIGPN ATLVFDVKLV


 


251
KIGAPENAPA KQPAQVDIKK VN*






a576-1/m576-1 99.6% identity in 272 aa overlap





Expression of ORF 576
The primer described in Table 1 for ORF 576 was used to locate and clone ORF 576. ORF 576 was cloned in pET and pGex vectors and expressed in E. coli as above described. The products of protein expression and purification were analyzed by SDS-PAGE. FIG. 3A shows the results of affinity purification and FIG. 3B shows the expression in E. coli. Purified His-fusion protein was used to immunize mice, whose sera were used for ELISA (positive result), FACS analysis (FIG. 3C), western blot (FIG. 3D). These experiments confirm that ORF 576 is a surface-exposed protein and that it is a useful immunogen. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 576 are provided in FIG. 7. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 576 and the amino acid sequence encoded thereby is provided in Example 1.
The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1749>:









g577.seq..




1
atggaaagga gcggtgtatt tggtaaaatt gtcggcaatc gcatactccg


 


51
tatgccgtcc gaacacgctg ccgcattcta tccgaaaccg tgcaaatcgt


 


101
ttaaactaac gcaatcttgg ttcagagtgc gaagctgtcc gtgcggcgtt


 


151
tttatttacg gagcaaacat gaaacttatc tataccgtca tcaaaatcat


 


201
tatcctgctg ctcttcctgc tgcttgccgt cattaatatg gatgccgtta


 


251
ccttttccta tcttccgggg cagagtgtca atctgccgct gattgtcgta


 


301
ttgttcggcg cgtttgtcgt cggcatcgtg ttcggaatgt ttgccctgtt


 


351
cgggcggctg ctgtccttgc gcggcgaaaa cagccgcctg cgtgcggaag


 


401
tgaagaaaag tgcgcgcttg agcggacaga aattgactgc accgccgata


 


451
caaaatgctg ccgaatctgc caaacagcct taa






This corresponds to the amino acid sequence <SEQ ID 1750; ORF 577.ng>:










g577.pep




1
MERSGVFGKI VGNRILRMPS EHAAAFYPKP CKSFKLTQSW FRVRSCPCGV


 


51
FIYGANMKLI YTVIKIIILL LFLLLAVINM DAVTFSYLPG QSVNLPLIVV


 


101
LFGAFVVGIV FGMFALFGRL LSLRGENSRL RAEVKKSARL SGQKLTAPPI


 


151
QNAAESAKQP *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1751>:










m577.seq..




1
ATGGAAAGGA ACGGTGTATT TGGTAAAATT GTCGGCAATC GCATACTCCG


 


51
TATGTCGTCC GAACACGCTG CCGCATCCTA TCCGAAACCG TGCAAATCGT


 


101
TTAAACTAGC GCAATCTTGG TTCAGAGTGC GAAGCTGTCT GGGCGGCGTT


 


151
TTTATTTACG GAGCAAACAT GAAACTTATC TATACCGTCA TCAAAATCAT


 


201
TATCCTGCTG CTCTTCCTGC TGCTTGCCGT CATTAATACG GATGCCGTTA


 


251
CCTTTTCCTA CCTGCCGGGG CAAAAATTCG ATTTGCCGCT GATTGTCGTA


 


301
TTGTTCGGCG CATTTGTAGT CGGTATTATT TTTGGAATGT TTGCCTTGTT


 


351
CGGACGGTTG TTGTCGTTAC GTGGCGAGAA CGGCAGGTTG CGTGCCGAAG


 


401
TAAAGAAAAA TGCGCGTTTG ACGGGGAAGG AGCTGACCGC ACCACCGGCG


 


451
CAAAATGCGC CCGAATCTAC CAAACAGCCT TAA






This corresponds to the amino acid sequence <SEQ ID 1752; ORF 577>:










m577.pep..




1
MERNGVFGKI VGNRILRMSS EHAAASYPKP CKSFKLAQSW FRVRSCLGGV


 


51
FIYGANMKLI YTVIKIIILL LFLLLAVINT DAVTFSYLPG QKFDLPLIVV


 


101
LFGAFVVGII FGMFALFGRL LSLRGENGRL RAEVKKNARL TGKELTAPPA


 


151
QNAPESTKQP *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m577/g577 88.1% identity in 160 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1753>:










a577.seq




1
ATGGAAAGGA ACGGTGTATT TGGTAAAATT GTCGGCAATC GCATACTCCG


 


51
TATGTCGTCC GAACACGCTG CCGCATCCTA TCCGAAACCG TGCAAATCGT


 


101
TTAAACTAGC GCAATCTTGG TTCAGAGTGC GAAGCTGTCC GGGCGGCGTT


 


151
TTTATTTACG GAGCAAACAT GAAACTTATC TATACCGTCA TCAAAATCAT


 


201
TATCCTGCTG CTCTTCCTGC TGCTTGCTGT CATTAATACG GATGCCGTTA


 


251
CCTTTTCCTA CCTGCCGGGG CAAAAATTCG ATTTGCCGCT GATTGTCGTA


 


301
TTGTTCGGCG CGTTTGTCGT CGGCATCGTG TTCGGAATGT TTGCCTTGTT


 


351
CGGACGGTTG TTGTCGTTAC GTGGCGAGAA CGGCAGGTTG CGTGCCGAAG


 


401
TAAAGAAAAA TGCGCGTTTG ACGGGGAAGG AGCTGACCGC ACCACCGGCG


 


451
CAAAATGCGC CCGAATCTGC CAAACAGCCT TGA






This corresponds to the amino acid sequence <SEQ ID 1754; ORF 577.a>:










a577.pep




1
MERNGVFGKI VGNRILRMSS EHAAASYPKP CKSFKLAQSW FRVRSCPGGV


 


51
FIYGANMKLI YTVIKIIILL LFLLLAVINT DAVTFSYLPG QKFDLPLIVV


 


101
LFGAFVVGIV FGMFALFGRL LSLRGENGRL RAEVKKNARL TGKELTAPPA


 


151
QNAPESAKQP *






m577/a577 98.1% identity in 160 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1755>:










g578.seq..




1
atgggaaagc tcgacatcgg gatattgttt gccgatttct tcaaagattt


 


51
cgcgccacag ttcggtggtt tccaaaacgt tggctttgcc tacggagcag


 


101
acttttttgc tgcgtttttg ggcggattgg aaggccacgt gggcgatgcg


 


151
gcggatttcg ctttcgctgt atttcatggt gttgtagcct tcgtgttcgc


 


201
cgttttccaa aacacggatg ccgcgcggtt cgccgaaata aatatcgccg


 


251
gtaagttcgc gcacaatcaa aatatccaaa ccggcaacga tttcaggctt


 


301
gagcgtggag gcgttggcta a






This corresponds to the amino acid sequence <SEQ ID 1756; ORF 578.ng>:










g578.pep




1
MGKLDIGILF ADFFKDFAPQ FGGFQNVGFA YGADFFAAFL GGLEGHVGDA


 


51
ADFAFAVFHG VVAFVFAVFQ NTDAARFAEI NIAGKFAHNQ NIQTGNDFRL


 


101
ERGGVG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1757>:










m578.seq..




1
ATGGGAAAGC TCGACATCAG GGTACTCTTT GCCGATTTCT TCAAAGATTT


 


51
CGCGCCACAA TTCGGTGGTT TCCAAAACGT TGGCTTTGCC TACGGAACAG


 


101
ACTTTTTTGC TGCGTTTTTG GGCGGATTGG AAGGCAACAT GGGCAATACG


 


151
GCGGATTTCG CTTTCGCTGT ATTTCATGGT GTTGTAGCCT TCGCGTTCGC


 


201
CGTTTTCCAG AACGCGGATG CCGCGCGGTT CGCCGAAATA GATGTCGCCG


 


251
GTGAGTTCGC GCACAATCAA AATATCCAAA CCGGCAACGA TTTCAGGCTT






This corresponds to the amino acid sequence <SEQ ID 1758; ORF 578>:










m578.pep..




1
MGKLDIRVLF ADFFKDFAPQ FGGFQNVGFA YGTDFFAAFL GGLEGNMGNT


 


51
ADFAFAVFHG VVAFAFAVFQ NADAARFAEI DVAGEFAHNQ NIQTGNDFRL


 


101
QRGGVG*






m578/g578 87.7% identity in 106 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1759>:










a578.seq




1
ATGGGAAAGC TCGACATCAG GGTATTCTTT GCCGATTTCT TCAAAGATTT


 


51
CGCGCCACAA TTCGGTGGTT TCCAAAACGT TGGCTTTGCC TACGGAGCAG


 


101
ACTTTTTTGC TGCGTTTTTG GGCGGATTGG AAGGCGACGT GGGCAATACG


 


151
GCGGATTTCG CTTTCGCTGT ATTTCATGGT GTTGTAGCCT TCGCGTTCGC


 


201
CGTTTTCCAG AACACGGATG CCGCGCGGTT CGCCGAAATA AATATCGCCG


 


251
GTGAGTTCGC GCACAATCAA AATATCCAAA CCCGCAACGA TTTCAGACTT


 


301
GAGCGTGGAG GCGTTGGCTA G






This corresponds to the amino acid sequence <SEQ ID 1760; ORF 578.a>:










a578.pep




1
MGKLDIRVFF ADFFKDFAPQ FGGFQNVGFA YGADFFAAFL GGLEGDVGNT


 


51
ADFAFAVFHG VVAFAFAVFQ NTDAARFAEI NIAGEFAHNQ NIQTRNDFRL


 


101
ERGGVG*






m578/a578 91.5% identity in 106 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1761>:

g579.seq.









g579.seq..




1
ATGAGGGCGG CGATGACGCG CGCGCAGGTC GATGCCACGC TGATTAGTTT


 


51
TTTGTGTAAT GTTGCCAATA TCGGCTTATT GATTTTGGTG ATTATTGCCG


 


101
CATTGGGACG GTTGGGCGTT TCCACAACAT CCGTAACCGC CTTAATCGGC


 


151
GGCGCGGGTT TGGCGGTGGC GTTGTCCTTA AAAGACCAGC TGTCCAATTT


 


201
TGCCGCCGGC GCGCTGATTA TCCTGTTCCG CCCGTTCAAA GTCGGCGACT


 


251
TTATCCGTGT CGGCGGTTTT GAAGGATATG TCCGGGAAAT CAAAATGGTG


 


301
CAGACTTCTT TGCGGACGAC CGACAACGAA GAAGTCGTGC TGCCCAACAG


 


351
CGTGGTGATG GGCAACAGCA TCGTCAACCG TTCCAGCCTG CCGCTTTGCC


 


401
GCGCCCAAGT GATAGTCGGC GTCGATTACA ACTGCGATTT GAAAGTGGCG


 


451
AAAGAGGCGG TGTTGAAAGC CGCCGCCGAA CACCCCTTGA GCGTTCAAAA


 


501
CGAAGAGCGG CAGCCCGCCG CCTACATCAC CGCCTTGGGC GACAATGCCA


 


551
TCGAAATCAC ATTATGGGCT TGGGCAAACG AAGCAGACCG CTGGACGCTG


 


601
CAATGCGACT TGAACGAACA AGTGGTCGAA AACCTCCGCA AAGTCAATAT


 


651
CAACATCCCG TTCCCGCAAC GCGACATACA CATCATCAAT TCTTAA






This corresponds to the amino acid sequence <SEQ ID 1762: ORF 579 ng>.










g579.pep..




1
MRAAMTRAQV DATLISFLCN VANIGLLILV IIAALGRLGV STTSVTALIG


 


51
GAGLAVALSL KDQLSNFAAG ALIILFRPFK VGDFIRVGGF EGYVREIKMV


 


101
QTSLRTTDNE EVVLPNSVVM GNSIVNRSSL PLCRAQVIVG VDYNCDLKVA


 


151
KEAVLKAAAE HPLSVQNEER QPAAYITALG DNAIEITLWA WANEADRWTL


 


201
QCDLNEQVVE NLRKVNINIP FPQRDIHIIN S*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1763>:










m579.seq..




1
ATGAGGGCGG CGATGACGCG CGCGCAGGTC GATGCCACGC TGATTAGTTT


 


51
TTTGTGTAAT GTTGCCAATA TCGGCTTATT GATTTTGGTG ATTATTGCCG


 


101
CATTGGGCAG ATTGGGCGTT TCCACAACAT CCGTAACCGC CTTAATCGGC


 


151
GGCGCGGGTT TGGCGGTGGC GTTGTCCCTG AAAGACCAGC TGTCCAATTT


 


201
TGCCGCCGGC GCACTGATTA TCCTGTTCCG CCCGTTCAAA GTCGGCGATT


 


251
TTATCCGCGT CGGCGGTTTT GAAGGATATG TCCGAGAGAT TAAAATGGTG


 


301
CAGACTTCTT TGCGGACGAC CGACAACGAA GAAGTCGTGC TGCCCAACAG


 


351
CGTGGTGATG GGCAACAGCA TCGTCAACCG TTCCACACTG CCGCTGTGCC


 


401
GCGCCCAAGT GATAGTCGGC GTCGATTACA ACTGCGATTT GAAAGTGGCG


 


451
AAAGAGGCGG TGTTGAAAGC CGCCGTCGAA CACCCCTTGA GCGTTCAAAA


 


501
CGAAGAGCGG CAGGCTGCCG CCTACATCAC CGCCTTGGGC GACAATGCCA


 


551
TCGAAATCAC ATTATGGGCT TGGGCAAACG AAGCAGACCG CTGGACGCTG


 


601
CAATGCGACT TGAACGAACA AGTGGTCGAA AACCTCCGCA AAGTCAATAT


 


651
CAACATCCCG TTCCCGCAAC GCGACATACA CATCATCAAT TCTTAA






This corresponds to the amino acid sequence <SEQ ID 1764; ORF 579>:










m579.pep..




1
MRAAMTRAQV DATLISFLCN VANIGLLILV IIAALGRLGV STTSVTALIG


 


51
GAGLAVALSL KDQLSNFAAG ALIILFRPFK VGDFIRVGGF EGYVREIKMV


 


101
QTSLRTTDNE EVVLPNSVVM GNSIVNRSTL PLCRAQVIVG VDYNCDLKVA


 


151
KEAVLKAAVE HPLSVQNEER QAAAYITALG DNAIEITLWA WANEADRWTL


 


201
QCDLNEQVVE NLRKVNINIP FPQRDIHIIN S*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m579/g579 98.7% identity in 231 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1765>:










a579.seq




1
ATGAGGGCGG CGATGACGCG CGCGCAGGTC GATGCCACGC TGATTAGTTT


 


51
TTTGTGTAAT GTTGCCAATA TCGGCTTATT GATTTTGGTG ATTATTGCCG


 


101
CATTGGGCAG ATTGGGCGTT TCCACAACAT CCGTAACCGC CTTAATCGGC


 


151
GGCGCGGGTT TGGCGGTGGC GTTGTCCTTG AAAGACCAGC TGTCCAATTT


 


201
TGCCGCCGGC GCGCTGATTA TCCTGTTCCG CCCGTTCAAA GTCGGCGATT


 


251
TTATCCGCGT CGGCGGTTTT GAAGGATATG TCCGAGAGAT TAAAATGGTG


 


301
CAGACTTCTT TGCGGACGAC CGACAACGAA GAAGTCGTGC TGCCCAACAG


 


351
CGTGGTGATG GGCAACAGCA TCGTCAACCG TTCCACACTG CCGCTGTGCC


 


401
GCGCCCAAGT GATAGTCGGC GTCGATTACA ACTGCGATTT GAAAGTGGCG


 


451
AAAGAGGCGG TGTTGAAAGC CGCCGTCGAA CACCCCTTGA GCGTTCAAAA


 


501
CGAAGAGCGG CAGGCCGCCG CCTACATCAC CGCCTTGGGC GACAATGCCA


 


551
TCGAAATCAC ATTATGGGCT TGGGCAAACG AAGCAGACCG CTGGACGCTG


 


601
CAATGCGACT TGAACGAACA AGTGGTCGAA AACCTCCGCA AAGTCAATAT


 


651
CAACATCCCG TTCCCGCAAC GCGACATACA CATCATCAAT TCTTAA






This corresponds to the amino acid sequence <SEQ ID 1766; ORF 579.a>:










a579.pep




1
MRAAMTRAQV DATLISFLCN VANIGLLILV IIAALGRLGV STTSVTALIG


 


51
GAGLAVALSL KDQLSNFAAG ALIILFRPFK VGDFIRVGGF EGYVREIKMV


 


101
QTSLRTTDNE EVVLPNSVVM GNSIVNRSTL PLCRAQVIVG VDYNCDLKVA


 


151
KEAVLKAAVE HPLSVQNEER QAAAYITALG DNAIEITLWA WANEADRWTL


 


201
QCDLNEQVVE NLRKVNINIP FPQRDIHIIN S*






m579/a579 100.0% identity in 231 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1767>:










g579-1.seq




1
ATGGACTTCA AACAATTTGA TTTTTTACAC CTGATCAGTG TTTCCGGTTG


 


51
GGGGCATCTG GCTGAAAAGG CGTGGGCGTT CGGGCTGAAC CTTGCCGCCG


 


101
CGCTGCTTAT TTTCTTGGTC GGGAAATGGG CGGCGAAACG CATTGTCGCC


 


151
GTAATGAGGG CGGCGATGAC GCGCGCGCAG GTCGATGCCA CGCTGATTAG


 


201
TTTTTTGTGT AATGTTGCCA ATATCGGCTT ATTGATTTTG GTGATTATTG


 


251
CCGCATTGGG ACGGTTGGGC GTTTCCACAA CATCCGTAAC CGCCTTAATC


 


301
GGCGGCGCGG GTTTGGCGGT GGCGTTGTCC TTAAAAGACC AGCTGTCCAA


 


351
TTTTGCCGCC GGCGCGCTGA TTATCCTGTT CCGCCCGTTC AAAGTCGGCG


 


401
ACTTTATCCG TGTCGGCGGT TTTGAAGGAT ATGTCCGGGA AATCAAAATG


 


451
GTGCAGACTT CTTTGCGGAC GACCGACAAC GAAGAAGTCG TGCTGCCCAA


 


501
CAGCGTGGTG ATGGGCAACA GCATCGTCAA CCGTTCCAGC CTGCCGCTTT


 


551
GCCGCGCCCA AGTGATAGTC GGCGTCGATT ACAACTGCGA TTTGAAAGTG


 


601
GCGAAAGAGG CGGTGTTGAA AGCCGCCGCC GAACACCCCT TGAGCGTTCA


 


651
AAACGAAGAG CGGCAGCCCG CCGCCTACAT CACCGCCTTG GGCGACAATG


 


701
CCATCGAAAT CACATTATGG GCTTGGGCAA ACGAAGCAGA CCGCTGGACG


 


751
CTGCAATGCG ACTTGAACGA ACAAGTGGTC GAAAACCTCC GCAAAGTCAA


 


801
TATCAACATC CCGTTCCCGC AACGCGACAT ACACATCATC AATTCTTAA






This corresponds to the amino acid sequence <SEQ ID 1768; ORF 579.a>:










g579-1.pep




1
MDFKQFDFLH LISVSGWGHL AEKAWAFGLN LAAALLIFLV GKWAAKRIVA


 


51
VMRAAMTRAQ VDATLISFLC NVANIGLLIL VIIAALGRLG VSTTSVTALI


 


101
GGAGLAVALS LKDQLSNFAA GALIILFRPF KVGDFIRVGG FEGYVREIKM


 


151
VQTSLRTTDN EEVVLPNSVV MGNSIVNRSS LPLCRAQVIV GVDYNCDLKV


 


201
AKEAVLKAAA EHPLSVQNEE RQPAAYITAL GDNAIEITLW AWANEADRWT


 


251
LQCDLNEQVV ENLRKVNINI PFPQRDIHII NS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1769>:










m579-1.seq




1
ATGGACTTCA AACAATTTGA TTTTTTACAC CTGATCAGTG TTTCCGGTTG


 


51
GGAGCATCTG GCTGAAAAGG CGTGGGCGTT CGGGCTGAAC CTTGCCGCCG


 


101
CGCTGCTTAT TTTTTTGGTC GGAAAATGGG CGGCGAAACG CATTGTCGCT


 


151
GTGATGAGGG CGGCGATGAC GCGCGCGCAG GTCGATGCCA CGCTGATTAG


 


201
TTTTTTGTGT AATGTTGCCA ATATCGGCTT ATTGATTTTG GTGATTATTG


 


251
CCGCATTGGG CAGATTGGGC GTTTCCACAA CATCCGTAAC CGCCTTAATC


 


301
GGCGGCGCGG GTTTGGCGGT GGCGTTGTCC CTGAAAGACC AGCTGTCCAA


 


351
TTTTGCCGCC GGCGCACTGA TTATCCTGTT CCGCCCGTTC AAAGTCGGCG


 


401
ATTTTATCCG CGTCGGCGGT TTTGAAGGAT ATGTCCGAGA GATTAAAATG


 


451
GTGCAGACTT CTTTGCGGAC GACCGACAAC GAAGAAGTCG TGCTGCCCAA


 


501
CAGCGTGGTG ATGGGCAACA GCATCGTCAA CCGTTCCACA CTGCCGCTGT


 


551
GCCGCGCCCA AGTGATAGTC GGCGTCGATT ACAACTGCGA TTTGAAAGTG


 


601
GCGAAAGAGG CGGTGTTGAA AGCCGCCGTC GAACACCCCT TGAGCGTTCA


 


651
AAACGAAGAG CGGCAGGCTG CCGCCTACAT CACCGCCTTG GGCGACAATG


 


701
CCATCGAAAT CACATTATGG GCTTGGGCAA ACGAAGCAGA CCGCTGGACG


 


751
CTGCAATGCG ACTTGAACGA ACAAGTGGTC GAAAACCTCC GCAAAGTCAA


 


801
TATCAACATC CCGTTCCCGC AACGCGACAT ACACATCATC AATTCTTAA






This corresponds to the amino acid sequence <SEQ ID 1770; ORF 579-1>:










m579-1.pep




1
MDFKQFDFLH LISVSGWEHL AEKAWAFGLN LAAALLIFLV GKWAAKRIVA


 


51
VMRAAMTRAQ VDATLISFLC NVANIGLLIL VIIAALGRLG VSTTSVTALI


 


101
GGAGLAVALS LKDQLSNFAA GALIILFRPF KVGDFIRVGG FEGYVREIKM


 


151
VQTSLRTTDN EEVVLPNSVV MGNSIVNRST LPLCRAQVIV GVDYNCDLKV


 


201
AKEAVLKAAV EHPLSVQNEE RQAAAYITAL GDNAIEITLW AWANEADRWT


 


251
LQCDLNEQVV ENLRKVNINI PFPQRDIHII NS*






m579-1/g579-1 98.6% identity in 282 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1771>:










a579-1.seq




1
ATGGACTTCA AACAATTTGA TTTTTTACAC CTGATAAGTG CTTCCGGCTG


 


51
GGAGCATCTG GCTGAAAAGG CGTGGGCGTT CGGGCTGAAC CTTGCCGCCG


 


101
CGCTGCTTAT TTTTTTGGTC GGAAAATGGG CGGCGAAACG CATTGTCGCC


 


151
GTGATGAGGG CGGCGATGAC GCGCGCGCAG GTCGATGCCA CGCTGATTAG


 


201
TTTTTTGTGT AATGTTGCCA ATATCGGCTT ATTGATTTTG GTGATTATTG


 


251
CCGCATTGGG CAGATTGGGC GTTTCCACAA CATCCGTAAC CGCCTTAATC


 


301
GGCGGCGCGG GTTTGGCGGT GGCGTTGTCC TTGAAAGACC AGCTGTCCAA


 


351
TTTTGCCGCC GGCGCGCTGA TTATCCTGTT CCGCCCGTTC AAAGTCGGCG


 


401
ATTTTATCCG CGTCGGCGGT TTTGAAGGAT ATGTCCGAGA GATTAAAATG


 


451
GTGCAGACTT CTTTGCGGAC GACCGACAAC GAAGAAGTCG TGCTGCCCAA


 


501
CAGCGTGGTG ATGGGCAACA GCATCGTCAA CCGTTCCACA CTGCCGCTGT


 


551
GCCGCGCCCA AGTGATAGTC GGCGTCGATT ACAACTGCGA TTTGAAAGTG


 


601
GCGAAAGAGG CGGTGTTGAA AGCCGCCGTC GAACACCCCT TGAGCGTTCA


 


651
AAACGAAGAG CGGCAGGCCG CCGCCTACAT CACCGCCTTG GGCGACAATG


 


701
CCATCGAAAT CACATTATGG GCTTGGGCAA ACGAAGCAGA CCGCTGGACG


 


751
CTGCAATGCG ACTTGAACGA ACAAGTGGTC GAAAACCTCC GCAAAGTCAA


 


801
TATCAACATC CCGTTCCCGC AACGCGACAT ACACATCATC AATTCTTAA






This corresponds to the amino acid sequence <SEQ ID 1772; ORF 579-1.a>:










a579-1.pep




1
MDFKQFDFLH LISASGWEHL AEKAWAFGLN LAAALLIFLV GKWAAKRIVA


 


51
VMRAAMTRAQ VDATLISFLC NVANIGLLIL VIIAALGRLG VSTTSVTALI


 


101
GGAGLAVALS LKDQLSNFAA GALIILFRPF KVGDFIRVGG FEGYVREIKM


 


151
VQTSLRTTDN EEVVLPNSVV MGNSIVNRST LPLCRAQVIV GVDYNCDLKV


 


201
AKEAVLKAAV EHPLSVQNEE RQAAAYITAL GDNAIEITLW AWANEADRWT


 


251
LQCDLNEQVV ENLRKVNINI PFPQRDIHII NS*






a579-1/m579-1 99.6% identity in 282 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1773>:










g580.seq




1
atggattcgc ccaaggtcgg gtgcgggtgg atggttttgc cgatgtctgc


 


51
cgcgtcgcag cccatttcga tggcaaggca gacttcgccg atcatgtcgc


 


101
caccgttcgg accgacaatg ccgccgccga tgatgcggcc ggtttcggca


 


151
tcgaaaatca gcttggtaaa gccgttgtcg caaccgttgg caatcgcacg


 


201
accggaagcc gcccatggga agttggcttt ggtaattttg cggcctgatg


 


251
ctttggcaga caattcggtt tcaccgaccc atgccacttc gggggaagtg


 


301
tag






This corresponds to the amino acid sequence <SEQ ID 1774; ORF 580.ng>:










g580.pep..




1
MDSPKVGCGW MVLPMSAASQ PISMARQTSP IMSPPFGPTM PPPMMRPVSA


 


51
SKISLVKPLS QPLAIARPEA AHGKLALVIL RPDALADNSV SPTHATSGEV


 


101
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1775>:










m580.seq..




1
ATGGATTCGC CCAAGGTCGG GTGCGGGTGG ATGGTTTTGC CGATGTCTGC


 


51
CGCGTCGCAG CCCATTTCGA TGGCAAGGCA GACTTCGCCG ATCATATCGC


 


101
CACCGTTCGG ACCGACAATG CCGCCGCCGA TGATGCGGCC GGTTTCGGCA


 


151
TCAAAAATCA GCTTGGTAAA GCCGTTGTCG CAACCGTTGG CAATCGCACG


 


201
GCCGGAAGCC GCCCACGGGA AGTTGGCTTT GGTGATTTTG CGGCCGGAGG


 


251
CTTTGGCGGA CAGTTCGGTT TCGCCCACCC ACGCCACTTC GGGGGAAGTG


 


301
TAG






This corresponds to the amino acid sequence <SEQ ID 1776; ORF 580>:










m580.pep..




1
MDSPKVGCGW MVLPMSAASQ PISMARQTSP IISPPFGPTM PPPMMRPVSA


 


51
SKISLVKPLS QPLAIARPEA AHGKLALVIL RPEALADSSV SPTHATSGEV


 


101
*






m580/g580 97.0% identity in 100 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1777>:










a580.seq




1
ATGGATTCGC CCAAGGTCGG GTGCGGGTGG ATGGTTTTGC CGATGTCTGC


 


51
CGCGTCGCAG CCCATTTCGA TGGCAAGGCA GACTTCGCCG ATCATGTCGC


 


101
CACCGTTCGG ACCGACAATG CCGCCGCCGA TGATGCGGCC GGTTTCAGCA


 


151
TCAAAAATCA GCTTGGTGAA ACCATTGTCG CAACCGTTGG CAATCGCACG


 


201
GCCGGAAGCA GCCCATGGGA AGTTGGCTTT GGTGATTTTG CGGCCGGAGG


 


251
CTTTGGCAGA CAATTCGGTT TCGCCCACCC ATGCCACTTC AGGAGAAGTG


 


301
TAA






This corresponds to the amino acid sequence <SEQ ID 1778; ORF 580.a>:










a580.pep




1
MDSPKVGCGW MVLPMSAASQ PISMARQTSP IMSPPFGPTM PPPMMRPVSA


 


51
SKISLVKPLS QPLAIARPEA AHGKLALVIL RPEALADNSV SPTHATSGEV


 


101
*






m580/a580 98.0% identity in 100 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1779>:










g581.seq..




1
atgcacttcg cccagcttgt gggtcaaacc ggtatagaac aaaatacgtt


 


51
ctgtcgtcgt ggttttaccc gcatcgatat gggcggaaat accgatgttg


 


101
cggtacaggc tgatcggggt cttacgagcc attttattag cctttcaaaa


 


151
ttagaaacgg aagtgagaga atgctttgtt ggcttcagcc atacggtgta


 


201
cttcttcacg ttttttcaac gcaccgccac ggccttcgga cgcatcaatc


 


251
aactcgcctg ccaaacgcag atccatggat ttctcaccac gtttgcgggc


 


301
cgcgtcgcga acccaacgca ttgccaaagc cagacggcgt ga






This corresponds to the amino acid sequence <SEQ ID 1780; ORF 581.ng>:










g581.pep..




1
MHFAQLVGQT GIEQNTFCRR GFTRIDMGGN TDVAVQADRG LTSHFISLSK


 


51
LETEVRECFV GFSHTVYFFT FFQRTATAFG RINQLACQTQ IHGFLTTFAG


 


101
RVANPTHCQS QTA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1781>:










m581.seq..




1
ATGCACTTCG CCCAGCTTGT GGGTCAAACC GGTATAGAAC AAAATACGTT


 


51
CTGTCGTCGT GGTTTTACCC GCGTCAATAT GGGCGGAAAT ACCGATGTTA


 


101
CGGTACAGGC TGATCGGGGT CTTACGAGCC ATTTTATTAG CCTTTCAAAA


 


151
TTAGAAACGG AAGTGAGAGA ATGCTTTGTT GGCTTCAGCC ATACGGTGTA


 


201
CTTCTTCACG TTTTTTCAAC GCACCGCCAC GGCCTTCGGA CGCATCAATC


 


251
AATTCGCCTG CCAAACGCAG GTCCATGGAT TTCTCACCAC GTTTGCGGGC


 


301
CGCATCGCGA ACCCAGCGCA TTGCCAAAGC CAAACGGCGT GA






This corresponds to the amino acid sequence <SEQ ID 1782; ORF 581>:










m581.pep..




1
MHFAQLVGQT GIEQNTFCRR GFTRVNMGGN TDVTVQADRG LTSHFISLSK



 


51
LETEVRECFV GFSHTVYFFT FFQRTATAFG RINQFACQTQ VHGFLTTFAG


 


101
RIANPAHCQS QTA*






m581/g581 93.8% identity in 113 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1783>:










a581.seq




1
ATGCACTTCG CCCAGCTTGT GGGTCAAACC GGTATAGAAC AAAATACGTT


 


51
CTGTCGTCGT GGTTTTACCC GCATCGATAT GGGCGGAAAT ACCGATGTTA


 


101
CGGTACAGGC TGATCGGGGT CTTACGAGCC ATTTTATTAG CCTTTCAAAA


 


151
TTAGAAACGG AAGTGAGAGA ATGCTTTGTT GGCTTCAGCC ATACGGTGTA


 


201
CTTCTTCACG TTTTTTCAAC GCACCGCCAC GGCCTTCGGA CGCATCAATC


 


251
AATTCGCCTG CCAAACGCAG GTCCATGGAT TTCTCACCAC GTTTGCGGGC


 


301
CGCATCGCGA ACCCAGCGCA TTGCCAAAGC CAAACGGCGT GA






This corresponds to the amino acid sequence <SEQ ID 1784; ORF 581.a>:










a581.pep




1
MHFAQLVGQT GIEQNTFCRR GFTRIDMGGN TDVTVQADRG LTSHFISLSK


 


51
LETEVRECFV GFSHTVYFFT FFQRTATAFG RINQFACQTQ VHGFLTTFAG


 


101
RINPAHCQS QTA*






m581/a581 98.2% identity in 113 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1785>:










g582.seq..




1
atgcgctata ttcttttgac aggactgttg ccgacggcat ccgcttttgg


 


51
agagaccgcg ctgcaatgcg ccgctttgac ggacaatgtt acgcgtttgg


 


101
cgtgttacga caggattttt gcggcacagc ttccgtcttc ggcagggcag


 


151
gaagggcagg agtcgaaagc cgtactcaat ctgacggaaa ccgtccgcag


 


201
cagcttggat aagggcgagg cggtcattgt tgttgaaaaa ggcggggatg


 


251
cgcttcctgc cgacagtgcg ggcgaaaccg ccgatatcta tacgcctttg


 


301
agcctgatgt acgacttgga caaaaacgat ttgcgcgggc tgttgggcgt


 


351
acgcgaacac aatccgatgt accttatgcc gttttggtat aacaattcgc


 


401
ccaactatgc cccgagttcg ccgacgcgcg gtacgactgt acaggaaaaa


 


451
ttcggacagc agaaacgtgc ggaaaccaaa ttgcaggttt cgttcaaaag


 


501
caaaattgcc gaaaatttgt ttaaaacccg cgcggatctg tggttcggct


 


551
acacccaaag atccgattgg cagatttaca accaaggcag gaaatccgcg


 


601
ccgttccgca atacggatta caaacctgaa attttcctga cccagcctgt


 


651
gaaggcggat ttgccgttcg gcggcaggct gcgtatgctc ggtgcgggtt


 


701
ttgtccacca gtccaacgga cagagccgtc ccgaatcgcg ttcgtggaac


 


751
aggatttatg ccatggcagg catggaatgg ggcaaattga cggtgattcc


 


801
gcgcgtgtgg gtgcgtgcgt tcgatcagag cggcgataaa aacgacaatc


 


851
ccgatattgc cgactatatg gggtatggcg acgtgaagct gcagtaccgc


 


901
ctgaacgaca ggcagaatgt gtattccgta ttgcgctaca accccaaaac


 


951
gggctacggc gcgattgaag ccgcctacac gtttccgatt aagggcaaac


 


1001
tcaaaggcgt ggtacgcgga ttccacggtt acggcgagag cctgatcgac


 


1051
tacaaccaca agcagaacgg tatcggtatc gggttgatgt tcaacgactg


 


1101
ggacggcatc tga






This corresponds to the amino acid sequence <SEQ ID 1786; ORF 582.ng>:










g582.pep..




1
MRYILLTGLL PTASAFGETA LQCAALTDNV TRLACYDRIF AAQLPSSAGQ


 


51
EGQESKAVLN LTETVRSSLD KGEAVIVVEK GGDALPADSA GETADIYTPL


 


101
SLMYDLDKND LRGLLGVREH NPMYLMPFWY NNSPNYAPSS PTRGTTVQEK


 


151
FGQQKRAETK LQVSFKSKIA ENLFKTRADL WFGYTQRSDW QIYNQGRKSA


 


201
PFRNTDYKPE IFLTQPVKAD LPFGGRLRML GAGFVHQSNG QSRPESRSWN


 


251
RIYAMAGMEW GKLTVIPRVW VRAFDQSGDK NDNPDIADYM GYGDVKLQYR


 


301
LNDRQNVYSV LRYNPKTGYG AIEAAYTFPI KGKLKGVVRG FHGYGESLID


 


351
YNHKQNGIGI GLMFNDWDGI *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1787>:










m582.seq
..



1
ATGCGCTATA TTCTTTTGAC AGGACTGTTG CCGATGGCAT CCGCTTTTGG


 


51
AGAGACCGCG CTGCAATGCG CCGCTTTGAC GGACAATGTT ACGCGTTTGG


 


101
CGTGTTACGA CAGGATTTTT GCGGCACAGC TTCCGTCTTC GGCAGGGCAG


 


151
GAAGGGCAGG AGTCGAAAGC CGTACTCAAT CTGACGGAAA CCGTCCGCAG


 


201
CAGCCTGGAT AAGGGCGAGG CGGTCATTGT TGTTGAAAAA GGCGGGGATG


 


251
CGCTTCCTGC CGACAGTGCG GGCGAAACCG CCGACATCTA TACGCCTTTG


 


301
AGCCTGATGT ACGACTTGGA CAAAAACGAT TTGCGCGGGC TGTTGGGCGT


 


351
ACGCGAACAC AATCCGATGT ACCTTATGCC GCTCTGGTAC AACAATTCGC


 


401
CCAACTATGC CCCGGGTTCG CCGACGCGCG GTACGACTGT ACAGGAAAAA


 


451
TTCGGACAGC AGAAACGTGC GGAAACCAAA TTGCAGGTTT CGTTCAAAAG


 


501
CAAAATTGCC GAAGATTTGT TTAAAACCCG CGCGGATCTG TGGTTCGGCT


 


551
ACACCCAAAG ATCCGATTGG CAGATTTACA ACCAAGGCAG GAAATCCGCG


 


601
CCGTTCCGCA ATACGGATTA CAAACCTGAA ATTTTCCTGA CCCAGCCTGT


 


651
GAAGGCGGAT TTGCCGTTCG GCGGCAGGCT GCGTATGCTC GGTGCGGGTT


 


701
TTGTCCACCA GTCCAACGGA CAGAGCCGTC CCGAATCGCG TTCGTGGAAC


 


751
AGGATTTACG CCATGGCAGG CATGGAATGG GGCAAATTGA CGGTGATTCC


 


801
GCGCGTGTGG GTGCGTGCGT TCGATCAGAG CGGCGATAAA AACGACAATC


 


851
CCGATATTGC CGACTATATG GGGTATGGCG ACGTGAAGCT GCAGTACCGC


 


901
CTGAACGACA GGCAGAATGT GTATTCCGTA TTGCGCTACA ACCCCAAAAC


 


951
GGGCTACGGC GCGATTGAAG CCGCCTACAC GTTTCCGATT AAGGGCAAAC


 


1001
TCAAAGGCGT GGTACGCGGA TTCCACGGTT ACGGCGAGAG CCTGATCGAC


 


1051
TACAACCACA AGCAGAACGG TATCGGTATC GGGTTGATGT TCAACGACTT


 


1101
GGACGGCATC TGA






This corresponds to the amino acid sequence <SEQ ID 1788; ORF 582>:










m582.pep




1
MRYILLTGLL PMASAFGETA LQCAALTDNV TRLACYDRIF AAQLPSSAGQ


 


51
EGQESKAVLN LTETVRSSLD KGEAVIVVEK GGDALPADSA GETADIYTPL


 


101
SLMYDLDKND LRGLLGVREH NPMYLMPLWY NNSPNYAPGS PTRGTTVQEK


 


151
FGQQKRAETK LQVSFKSKIA EDLFKTRADL WFGYTQRSDW QIYNQGRKSA


 


201
PFRNTDYKPE IFLTQPVKAD LPFGGRLRML GAGFVHQSNG QSRPESRSWN


 


251
RIYAMAGMEW GKLTVIPRVW VRAFDQSGDK NDNPDIADYM GYGDVKLQYR


 


301
LNDRQNVYSV LRYNPKTGYG AIEAAYTFPI KGKLKGVVRG FHGYGESLID


 


351
YNHKQNGIGI GLMFNDLDGI *






m582/g582 98.6% identity in 370 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1789>:










a582.seq




1
ATGCGCTATA TTCTTTTGAC AGGACTGTTG CCGATGGCAT CCGCTTTTGG


 


51
AGAGACCGCG CTGCAATGCG CCGCTTTGAC GGACAATGTT ACGCGTTTGG


 


101
CGTGTTACGA CAGGATTTTT GCGGCACAGC TTCCGTCTTC GGCAGGGCAG


 


151
GAAGGGCAGG AGTCGAAAGC CGTACTCAAT CTGACGGAAA CCGTCCGCAG


 


201
CAGCCTGGAT AAGGGCGAGG CGGTCATTGT TGTTGAAAAA GGCGGGGATG


 


251
CGCTTCCTGC CGACAGTGCG GGCGAAACCG CCGACATCTA TACGCCTTTG


 


301
AGCCTGATGT ACGACTTGGA CAAAAACGAT TTGCGCGGGC TGTTGGGCGT


 


351
ACGCGAACAC AATCCGATGT ACCTTATGCC GCTCTGGTAC AACAATTCGC


 


401
CCAACTATGC CCCGGGTTCG CCGACGCGCG GTACGACTGT ACAGGAAAAA


 


451
TTCGGACAGC AGAAACGTGC GGAAACCAAA TTGCAGGTTT CGTTCAAAAG


 


501
CAAAATTGCC GAAGATTTGT TTAAAACCCG CGCGGATCTG TGGTTCGGCT


 


551
ACACCCAAAG ATCCGATTGG CAGATTTACA ACCAAGGCAG GAAATCCGCG


 


601
CCGTTCCGCA ATACGGATTA CAAACCTGAA ATTTTCCTGA CCCAGCCTGT


 


651
GAAGGCGGAT TTGCCGTTCG GCGGCAGGCT GCGTATGCTC GGTGCGGGTT


 


701
TTGTCCACCA GTCCAACGGA CAGAGCCGTC CCGAATCGCG TTCGTGGAAC


 


751
AGGATTTACG CCATGGCAGG CATGGAATGG GGCAAATTGA CGGTGATTCC


 


801
GCGCGTGTGG GTGCGTGCGT TCGATCAGAG CGGCGATAAA AACGACAATC


 


851
CCGATATTGC CGACTATATG GGGTATGGCG ACGTGAAGCT GCAGTACCGC


 


901
CTGAACGACA GGCAGAATGT GTATTCCGTA TTGCGCTACA ATCCCAAAAC


 


951
GGGCTACGGC GCGATTGAAG CCGCCTACAC GTTTCCGATT AAGGGCAAAC


 


1001
TCAAAGGCGT GGTACGCGGA TTCCACGGTT ACGGCGAGAG CCTGATCGAC


 


1051
TACAACCACA AGCAGAACGG TATCGGTATC GGGTTGATGT TCAACGACTT


 


1101
GGACGGCATC TGA






This corresponds to the amino acid sequence <SEQ ID 1790; ORF 582.a>:










a582.pep




1
MRYILLTGLL PMASAFGETA LQCAALTDNV TRLACYDRIF AAQLPSSAGQ


 


51
EGQESKAVLN LTETVRSSLD KGEAVIVVEK GGDALPADSA GETADIYTPL


 


101
SLMYDLDKND LRGLLGVREH NPMYLMPLWY NNSPNYAPGS PTRGTTVQEK


 


151
FGQQKRAETK LQVSFKSKIA EDLFKTRADL WFGYTQRSDW QIYNQGRKSA


 


201
PFRNTDYKPE IFLTQPVKAD LPFGGRLRML GAGFVHQSNG QSRPESRSWN


 


251
RIYAMAGMEW GKLTVIPRVW VRAFDQSGDK NDNPDIADYM GYGDVKLQYR


 


301
LNDRQNVYSV LRYNPKTGYG AIEAAYTFPI KGKLKGVVRG FHGYGESLID


 


351
YNHKQNGIGI GLMFNDLDGI *






m582/a582 100.0% identity in 370 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1791>:










g583.seq..




1
atgataattg accaaagcca aatatttacc catcttgcct tctgtgcctt


 


51
ttgcgggatt ggagccgtaa ctgccggcaa tcgactgcat aatcggatgt


 


101
ataatgccgc cgccgcgcgc ggtattggaa ggggtaacgg gagccagcag


 


151
cagttcggaa agagcgagac tgtaaccgat gcccagcgtt tttcttccaa


 


201
aaacggcgat aaacaaatat ccgatacgca tccccagccc tgttttgagc


 


251
aaaccgcgcg aaatcataac tgcgatggca atcagccaaa tcaacggatt


 


301
ggcgaacgca ctcaacgcat cgctcatcgc cgcgcccggt ttgtcggcgg


 


351
ttacgccggt tactgcgacc aacccgacgg caataatcga cagcgcgccc


 


401
aacggcataa ccttgccgat aatggcggca atcacaccga caaacatagc


 


451
cagcagcgtc caagcctgag gcttgacccc gtcgggtacg ggcagtgcca


 


501
aaaccagggc gcacaatact gcggcaatgg cgaggggtat cggtttgaaa


 


551
cccaatttca tcatattgac ctccgtaaaa aagaccgtcc cgaaaaatcg


 


601
gaaaaataa






This corresponds to the amino acid sequence <SEQ ID 1792; ORF 583.ng>:










g583.pep..




1
MIIDQSQIFT HLAFCAFCGI GAVTAGNRLH NRMYNAAAAR GIGRGNGSQQ


 


51
QFGKSETVTD AQRFSSKNGD KQISDTHPQP CFEQTARNHN CDGNQPNQRI


 


101
GERTQRIAHR RARFVGGYAG YCDQPDGNNR QRAQRHNLAD NGGNHTDKHS


 


151
QQRPSLRLDP VGYGQCQNQG AQYCGNGEGY RFETQFHHID LRKKDRPEKS


 


201
EK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1793>:










m583.seq..




1
ATGATAGTTG ACCAAAGCCA AATATTTACC CATCTTGCCT TCTGTGCCTT


 


51
TTGCGGGATT GGAGCCGTAA CTGCCGGCAA TCGACTGCAT AATCGGATGT


 


101
ATAATGCCGC CGCCGCGCGC GGTATTGGAA GGGGTAACGG GAGCCAGCAG


 


151
CAGTTCGGAA AGAGCGAGAC TGTAACCGAT GCCCAGCGTT TTTCTTCCAA


 


201
AAACGGCGAT AAACAAATAT CCGATACGCA TCCCCAGCCC TGTTTTGAGC


 


251
AAACCGCGCG AAATCATAAC TGCGATGGCA ATCAGCCAAA TCAACGGATT


 


301
GGCGAACGCA CTCAACGCAT CGCTCATCGC CGCGCCCGGT TTGTCGGCGG


 


351
TTACGCCGGT TACTGCGACC AACCCGACGG CAATAATCGA CAGCGCGCCC


 


401
AACGGCATGG CCTTGCCGAT AATGGCGGCA ATCACACCGA CAAACATGGC


 


451
CAGCAGCGTC CAAGCCTGAG GCTTGACCCC GTCGGGTACG GGCAGTGCCA


 


501
AAACCAGGGC GCACAATACT GCGGCAATGG CGAGGGGTAT CGGTTTGAAA


 


551
CCCAATTTCA TCATATTGAC CTCCGTAAAA AAGACCGTCC CGAAAAATCG


 


601
GAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 1794; ORF 583>:










m583.pep..




1
MIVDQSQIFT HLAFCAFCGI GAVTAGNRLH NRMYNAAAAR GIGRGNGSQQ


 


51
QFGKSETVTD AQRFSSKNGD KQISDTHPQP CFEQTARNHN CDGNQPNQRI


 


101
GERTQRIAHR RARFVGGYAG YCDQPDGNNR QRAQRHGLAD NGGNHTDKHG


 


151
QQRPSLRLDP VGYGQCQNQG AQYCGNGEGY RFETQFHHID LRKKDRPEKS


 


201
EK*






m583/g583 98.5% identity in 202 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1795>:










a583.seq




1
ATGATAGTTG ACCAAAGCCA AATATTTACC CATCTTGCCT TCTGTGCCTT


 


51
TTGCGGGATT GGAGCCGTAA CTGCCGGCAA TCGACTGCAT AATCGGATGT


 


101
ATAATGCCGC CGCCGCGCGC GGTATTGGAA GGGGTAACGG GAGCCAGCAG


 


151
CAGTTCGGAA AGAGCGAGAC TGTAACCGAT GCCCAGCGTT TTTCTTCCAA


 


201
AAACGGCGAT AAACAAATAT CCGATACGCA TCCCCAGCCC TGTTTTGAGC


 


251
AAACCGCGCG AAATCATAAC TGCGATGGCA ATCAGCCAAA TCAACGGATT


 


301
GGCGAACGCA CTCAACGCAT CGCTCATCGC CGCACCCGGT TTGTCGGCGG


 


351
TTACGCCGGT TACTGCGACC AACCCGACGG CAATAATCGA CAGCGCACCC


 


401
AACGGCATGG CCTTGCCGAT AATGGCGGCA ATCACACCGA TAAACATGGC


 


451
CAGCAGCGTC CAAGCCTGAG GCTTGACCCC GTCGGGTACG GGCAGTGCCA


 


501
AAACCAAGGC GCACAATACT GCGGCAATGG CGAGGGGTAT CGGTTTGAAA


 


551
CCCAATTTCA TCATATTGAC CTCCGTAAAA AAGACCGTCC CGAAAAATCG


 


601
GAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 1796; ORF 583.a>:










a583.pep




1
MIVDQSQIFT HLAFCAFCGI GAVTAGNRLH NRMYNAAAAR GIGRGNGSQQ


 


51
QFGKSETVTD AQRFSSKNGD KQISDTHPQP CFEQTARNHN CDGNQPNQRI


 


101
GERTQRIAHR RTRFVGGYAG YCDQPDGNNR QRTQRHGLAD NGGNHTDKHG


 


151
QQRPSLRLDP VGYGQCQNQG AQYCGNGEGY RFETQFHHID LRKKDRPEKS


 


201
EK*






m583/a583 99.0% identity in 202 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1797>:










g584.seq..




1
atgctgcgtt ctattttggc ggcttccctg ctggcggtat cttttccggc


 


51
ggcggctgag gcattgaatt acaatattgt cgaattttcc gaatcggcgg


 


101
gtatcgaggt ggctcaggat acaatgtccg cgcgtttcca ggtggcggcg


 


151
gaaggacggg acaaaaatgc cgtcaatgcc gagtttgtta aaaaattcaa


 


201
caatttcacc agaaaatcga aaaatggtag ctttaaaacc gaattggtat


 


251
cgcgcagtgc gatgccgcgc tatcaatata ccaacggcag acgcattcaa


 


301
acaggctggg aggagcgtgc ggaatttaag gcggagggca gggattttga


 


351
tgctttaaac cgttttattg ctgatgttca gacggatgct tcgcttgaag


 


401
ataccgattt cagcgtgtcg cgcgaacgcc gaaacgaggt catcgatcag


 


451
gtcagcaagg atgccgtttt gcgtttcaag gcgcgtgccg aaaaactggc


 


501
gggcgttctg ggtgcgtccg gttataaaat cgtcaaattg aattttgggc


 


551
aaatcggcag ccatattgcg ggcgatgggg ctgttcgggc aaaaatgctg


 


601
cgcgcgatgc cgatggcggc aagcgtcaat atgaagggta cggattcagc


 


651
cgcaccgggt gtggaggaaa tcagcatcag catcaatggg acggttcagt


 


701
tctaa






This corresponds to the amino acid sequence <SEQ ID 1798; ORF 584.ng>:









g584.pep Length:..










1
MLRSILAASL LAVSFPAAAE ALNYNIVEFS ESAGIEVAQD TMSARFQVAA



 


51
EGRDKNAVNA EFVKKFNNFT RKSKNGSFKT ELVSRSAMPR YQYTNGRRIQ


 


101
TGWEERAEFK AEGRDFDALN RFIADVQTDA SLEDTDFSVS RERRNEVIDQ


 


151
VSKDAVLRFK ARAEKLAGVL GASGYKIVKL NFGQIGSHIA GDGAVRAKML


 


201
RAMPMAASVN MKGTDSAAPG VEEISISING TVQF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1799>:










m584.seq..




1
ATGTTGCGTC TTGTTTTGGC GGCTTCGCTG TCGGCGGTAT CTTTTCCGGC


 


51
AGCGGCTGAA GCATTGAATT ACAATATTGT CGAATTTTCC GAATCGGCGG


 


101
GTGTCGAGGT GGCTCAGGAT ACAATGTCCG CACGTTTCCA AGTGACGGCG


 


151
GAAGGACGGG ACAAAAATGC CGTCAATGCT GAGTTTGTTA AAAAATTCAA


 


201
CAAGTTCATC AGAAAATCGA AAAATGGTAG CTTTAAAACC GAATTGGTAT


 


251
CGCGCAGTGC GATGCCGCGC TATCAATATA CCAACGGCAG ACGCATTCAA


 


301
ACAGGCTGGG AGGAGCGTGC GGAATTTAAG GTCGAAGGTA GAGATTTTGA


 


351
TGAGTTAAAC CGTTTTATTG CCGATATTCA AGCAGATGCC GCGTTGGmAT


 


401
ATACGGATTT CCATGTGTCG CGCGAACGCC GCAACGAGGT CATCkATCAG


 


451
GTCAGCAAGG ATGCCGTTTT GCGTTTCAAG GCGCGTGCCG AAAAGTTGGC


 


501
GGGCGTTTTG GGTGCGTCCG GTTATAAAAT CGTCAAATTG AATTTGGGAC


 


551
ACATCGGCAG CCATATCGCG GGAGGGGGAG CTGCTCAGGC AAAAATGCTT


 


601
CGTGCCATGC CGATGGCGGC AAGCGTCAAT ATGGAGGGTG CGGATTCCGC


 


651
CGCGCCTGGT GTGGAGGAAA TCAGCATCAG CGTCAATGGG ACGGTTCAGT


 


701
TCTGA






This corresponds to the amino acid sequence <SEQ ID 1800; ORF 584>:










m584.pep..




1
MLRLVLAASL SAVSFPAAAE ALNYNIVEFS ESAGVEVAQD TMSARFQVTA


 


51
EGRDKNAVNA EFVKKFNKFI RKSKNGSFKT ELVSRSAMPR YQYTNGRRIQ


 


101
TGWEERAEFK VEGRDFDELN RFIADIQADA ALXYTDFHVS RERRNEVIXQ


 


151
VSKDAVLRFK ARAEKLAGVL GASGYKIVKL NLGHIGSHIA GGGAAQAKML


 


201
RAMPMAASVN MEGADSAAPG VEEISISVNG TVQF*






m584/g584 89.7% identity in 234 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1801>:










a584.seq




1
ATGTTGCGTT CTATTTTGGC GGCTTCCCTG CTG....... ..........


 


51
.......... .......... .....ATTGT CGAATTTTCT GAATCGGCGG


 


101
GTGTCGAGGC GGTTCAGGAT ACAATGTCCG CACGTTTCCA AGTGACGGCG


 


151
GAAGGACGGG ACAAAAATGC CGTCAATGCC GAGTTTGTTA AAAAATTCAA


 


201
CAATTTCACC AGAAAATCAA AAAATGGTAG CTTTAAAACC GAATTGGTAT


 


251
CGCGCAGTGC GATGCCGCGC TATCAATATA CCAACGGCAG ACGCATTCAA


 


301
ACAGGTTGGG AGGAGCGTGC GGAATTTAAG GTCGAGGGTA GGAATTTTGA


 


351
TGCGTTGAAC CGTTTTATTG CCGATGTTCA GGCAGATGCC GCGTTGGAAT


 


401
ATACGGATTT CCATGTGTCG CGCGAACGCC GCAACGAGGT CATCGATCAG


 


451
GTCAGCAAGG ATGCCGTTTT GCGTTTCAAG GCGCGTGCCG AAAAGTTGGC


 


501
GGGCGTTTTG GGTGCGTCCG GTTATAAAAT CGTCAAATTG AATTTGGGAC


 


551
ACATCGGCAG CCATATCGCG GGAGGGGGAG CTGCTCAGGC AAAAATGCTT


 


601
CGTGCCATGC CGATGGCGGC AAGCGTCAAT ATGGAGGGTG CGGATTCCGC


 


651
CGCGCCTGGT GTGGAGGAAA TCAGCATCAG CGTCAATGGG ACGGTTCAGT


 


701
TCTGA






This corresponds to the amino acid sequence <SEQ ID 1802; ORF 584.a>:










a584.pep




1
MLRSILAASL L......... .....IVEFS ESAGVEAVQD TMSARFQVTA


 


51
EGRDKNAVNA EFVKKFNNFT RKSKNGSFKT ELVSRSAMPR YQYTNGRRIQ


 


101
TGWEERAEFK VEGRNFDALN RFIADVQADA ALEYTDFHVS RERRNEVIDQ


 


151
VSKDAVLRFK ARAEKLAGVL GASGYKIVKL NLGHIGSHIA GGGAAQAKML


 


201
RAMPMAASVN MEGADSAAPG VEEISISVNG TVQF*






m584/a584 88.9% identity in 234 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1803>:










g585.seq..




1
atgaaactgt tccaacgcat tttcgccaca ttttgcgcgg ttatcgtctg


 


51
cgcaatcttt gtggcgagtt tttctttttg gctggtgcag aacacccttg


 


101
ccgaaaacca attcaaccaa cgccgcacca tcgaaaccac attgatgggc


 


151
agcattattt ccgcattcaa gacacggggc gacaacggcg cgcgcgaaat


 


201
cctgaccgaa tggaaaaaca gccccgtctc atccgccgtt tacgtcatac


 


251
agggcgacga gaaaaaagac atcttaaacc gctatatcga caattacacc


 


301
atagaacgcg cccggctgtt tgccgccaac aacccccatt ccaaccttgt


 


351
ccgcatcgaa tacgaccgtt tcggcgaaga atacctgttc ttcattaaag


 


401
gctgggacaa ccaccaggca caacgcctgc ccagcccgct gtttatcccg


 


451
ggcctgccgc ttgccccgat ttggcacgaa ttcatcatcc tctccttcat


 


501
catcattgtc ggactgctga tggcatatat ccttgccggc aacattgcca


 


551
aacccatcag aatcttaggc aacggcatgg acagggtggc agaacgagaa


 


601
cttgaagacc gcgtttgcca acaggttcgc gaccgcgacg acgaattggc


 


651
cgatgttgcc atgcaattcg acacaatggt ggaaaaactg gaataa






This corresponds to the amino acid sequence <SEQ ID 1804; ORF 585.ng>:










g585.pep..




1
MKLFQRIFAT FCAVIVCAIF VASFSFWLVQ NTLAENQFNQ RRTIETTLMG


 


51
SIISAFKTRG DNGAREILTE WKNSPVSSAV YVIQGDEKKD ILNRYIDNYT


 


101
IERARLFAAN NPHSNLVRIE YDRFGEEYLF FIKGWDNHQA QRLPSPLFIP


 


151
GLPLAPIWHE FIILSFIIIV GLLMAYILAG NIAKPIRILG NGMDRVAERE


 


201
LEDRVCQQVR DRDDELADVA MQFDTMVEKL E*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1805>:










m585.seq..




1
ATGAAACTGT TCCAACGCAT TTTCGCCACA TTTTGCGCGG TTATCGTCTG


 


51
TGCAATCTTT GTGGCGAGTT TTTCTTTCTG GCTGGTGCAG AACACCCTTG


 


101
CCGAAAACCA GTTCAACCAA CGCCGCACCA TCGAAACCAC TTTGATGGGC


 


151
AGCATCATTT CCGCATTCCG GGCACGCGGG GACGCGGGTG CGCGCGAAAT


 


201
CCTGACGGAA TGGAAAGACA GCCCCGTCTC ATCGGGCGTG TACGTTATAC


 


251
AGGGCGACGA GAAAAAAGAT ATCCTGAACC GGTATATCGA CAGCTATACC


 


301
ATCGAACGCG CCCGGCTTTT CGCCGCCGGA CACCCGCATT CCAACCTCGT


 


351
CCATATCGAA TACGACCGCT TCGGCGAAGA ATACCTGTTC TTCACCAAAG


 


401
ACTGGGACAA ACTCCAAGCC CGCCGCCTGC CCAGCCCCCT GTTGATCCCC


 


451
GGCCTGCCGC TCGCCCCGAT TTGGCACGAA CTCATCATAT TGTCCTTCAT


 


501
CATCATCGTC GGACTGCTGA TGGCATATAT CCTCGCCGGC AACATTGCCA


 


551
AACCCATCAG AATCTTAGGC AACGGCATGG ACAGGGTGGC AAACGGAGAA


 


601
CTTGAAACCC GTATCTCCCA ACAGGTCGAC GACCGCGACG ACGAATTGTC


 


651
CCATCTTGCC ATCCAATTCG ACAAAATGGT GGAAAAACTC GAAAAACTCG


 


701
TTGCCAAAGA ACGCCACCTG CTCCATCACG TCTCCCATGA AATGCGTTCT


 


751
CCCCTTGCGC GCATGCAGGC AATTGTCGGA CTGATTCAGG CGCAGCCCCA


 


801
AAAACAGGAG CAATATCTCA AACGGCTGGA AGGCGAACTG ACCCGCATGG


 


851
ATACGCTGGC CGGGGAACTG TTAACCCTGT CCCGTCTCGA AACTTCCAAT


 


901
ATGGCTTTGG AAAAAGAAAG CCTGAAACTC CTGCCCTTCC TGGGCAACCT


 


951
GGTAGAAGAC AATCAAAGCA TTGCCCAGAA AAACGGACAA ACGGTTACCC


 


1001
TGTCTGCCGA CGGAAAAATC CCCGAAAACA CAACCATCCT TGCCAACGAA


 


1051
AGCTACCTGT ACCGCGCCTT CGACAACGTC ATCCGCAACG CCGTCAACTA


 


1101
CAGTCCCGAA GGCAGCACCA TCCTGATCAA CATCGGACAA GACCACAAAC


 


1151
ACTGGATAAT CGACGTTACC GACAACGGCC CCGGCGTGGA CGAAATGCAG


 


1201
CTCCCGCACA TCTTCACCGC TTTCTACCGT GCAGACTCCA GTGCCAACAA


 


1251
ACCCGGAACA GGACTGGGGC TTGCATTGAC CCAACATATT ATTGAACAGC


 


1301
ACTGCGGCAA AATCATCGCC GAAAACATCA AACCGAACGG TCTGCGGATG


 


1351
CGCTTTATCC TGCCCAAGAA AAAAACCGGT TCCAAAACAG AAAAAAGTGC


 


1401
GAACTGA






This corresponds to the amino acid sequence <SEQ ID 1806; ORF 585>:










m585.pep..




1
MKLFQRIFAT FCAVIVCAIF VASFSFWLVQ NTLAENQFNQ RRTIETTLMG


 


51
SIISAFRARG DAGAREILTE WKDSPVSSGV YVIQGDEKKD ILNRYIDSYT


 


101
IERARLFAAG HPHSNLVHIE YDRFGEEYLF FTKDWDKLQA RRLPSPLLIP


 


151
GLPLAPIWHE LIILSFIIIV GLLMAYILAG NIAKPIRILG NGMDRVANGE


 


201
LETRISQQVD DRDDELSHLA IQFDKMVEKL EKLVAKERHL LHHVSHEMRS


 


251
PLARMQAIVG LIQAQPQKQE QYLKRLEGEL TRMDTLAGEL LTLSRLETSN


 


301
MALEKESLKL LPFLGNLVED NQSIAQKNGQ TVTLSADGKI PENTTILANE


 


351
SYLYRAFDNV IRNAVNYSPE GSTILINIGQ DHKHWIIDVT DNGPGVDEMQ


 


401
LPHIFTAFYR ADSSANKPGT GLGLALTQHI IEQHCGKIIA ENIKPNGLRM


 


451
RFILPKKKTG SKTEKSAN*






m585/g585 88.3% identity in 231 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1807>:










a585.seq




1
ATGAAACTGT TCCAACGCAT CTTCGCCACA TTTTGCGCGG TTATCGTCTG


 


51
TGCAATCTTT GTGGCGAGTT TTTCTTTCTG GCTGGTGCAG AACACCCTTG


 


101
CCGAAAACCA GTTCAACCAA CGCCGCACCA TCGAAACCAC TTTGATGGGC


 


151
AGCATCATTT CCGCATTCCG GGCACGCGGG GACGCGGGTG CGCGCGAAAT


 


201
CCTGACGGAA TGGAAAGACA GCCCCGTCTC ATCGGGCGTG TACGTTATAC


 


251
AGGGCGACGA GAAAAAAGAT ATCCTGCACC GGTATATCGA CAGCTACACC


 


301
ATCGAACGCG CCCGGCTTTT CGCCGCCGGA CACCCGCATT CCAACCTCGT


 


351
CCATATCGAA TACGACCGCT TCGGCGAAGA ATACCTGTTC TTCACCAAAG


 


401
ACTGGGACAA ACTCCAAGCC CGCCGCCTGC CCAGCCCCCT GTTGATCCCC


 


451
GGCCTGCCGC TCGCCCCGAT TTGGCACGAA CTCATCATAT TGTCCTTCAT


 


501
CATCATCGTC GGACTGCTGA TGGCGTACAT CCTCGCCGGC AACATTGCCA


 


551
AACCCATCAG AATCTTAGGC AACGGCATGG ACAGGGTGGC AAACGGAGAA


 


601
CTTGAAACCC GTATCTCCCA ACAGGTCGAC GACCGCGACG ACGAATTGTC


 


651
CCATCTTGCC ATCCAATTCG ACAAAATGGT GGAAAAACTC GAAAAACTCG


 


701
TTGCCAAAGA ACGCCACCTG CTCCATCACG TCTCCCATGA AATGCGTTCT


 


751
CCCCTTGCGC GCATGCAGGC AATTGTCGGA CTGATTCAGG CGCAGCCCCA


 


801
AAAACAGGAG CAATATCTCA AACGGCTGGA AGGCGAACTG AACGGCATGG


 


851
ATACGCTGGC CGGGGAACTG TTAACCCTGT CCCGTCTCGA AACTTCCAAT


 


901
ATGGCTTTGG AAAAAGAAAG CCTGAAACTC CTGCCCTTCC TGGGCAACCT


 


951
GGTAGAAGAC AATCAAAGCA TTGCCCAGAA AAACGGACAA ACGGTTACCC


 


1001
TGTCTGCCGA CGGAAAAATC CCCGAAAACA CAACCATCCT TGCCAACGAA


 


1051
AGCTACCTGT ACCGCGCCTT CGACAACGTC ATCCGCAACG CCGTCAACTA


 


1101
CAGTCCCGAA GGCAGCACCA TCCTGATCAA CATCGGACAA GACCACAAAC


 


1151
ACTGGATAAT CGACGTTACC GACAACGGCC CCGGCGTGGA CGAAATGCAG


 


1201
CTCCCGCACA TCTTCACCGC TTTCTACCGT GCAGACTCCA GTGCCAACAA


 


1251
ACCCGGAACA GGACTGGGGC TTGCATTGAC CCAACATATT ATTGAACAGC


 


1301
ACTGCGGCAA AATCATCGCC GAAAACATCA AACCGAACGG TCTGCGGATG


 


1351
CGCTTTATCC TGCCCAAGAA AAAAACCGGT TCCAAAACAG AAAAAAGTGC


 


1401
GAACTGA






This corresponds to the amino acid sequence <SEQ ID 1808; ORF 585.a>:










a585.pep




1
MKLFQRIFAT FCAVIVCAIF VASFSFWLVQ NTLAENQFNQ RRTIETTLMG


 


51
SIISAFRARG DAGAREILTE WKDSPVSSGV YVIQGDEKKD ILHRYIDSYT


 


101
IERARLFAAG HPHSNLVHIE YDRFGEEYLF FTKDWDKLQA RRLPSPLLIP


 


151
GLPLAPIWHE LIILSFIIIV GLLMAYILAG NIAKPIRILG NGMDRVANGE


 


201
LETRISQQVD DRDDELSHLA IQFDKMVEKL EKLVAKERHL LHHVSHEMRS


 


251
PLARMQAIVG LIQAQPQKQE QYLKRLEGEL TRMDTLAGEL LTLSRLETSN


 


301
MALEKESLKL LPFLGNLVED NQSIAQKNGQ TVTLSADGKI PENTTILANE


 


351
SYLYRAFDNV IRNAVNYSPE GSTILINIGQ DHKHWIIDVT DNGPGVDEMQ


 


401
LPHIFTAFYR ADSSANKPGT GLGLALTQHI IEQHCGKIIA ENIKPNGLRM


 


451
RFILPKKKTG SKTEKSAN*






m585/a585 99.8% identity in 468 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1809>:










g586.seq..




1
atggcagccc atctcgaaga acaacaagag ttagacaact ttaaatattt


 


51
ttggaaaacc acgggcaaat ggctgtttgc cctgctgatt ttggcggcac


 


101
tcggctactt gggatacacg gtttaccaaa accgtgcggc ttcccaaaat


 


151
caggaagcgg cggcggtgct ggcaaacatc gtggaaaagg cgcaaaacaa


 


201
agccccgcaa agcgaaatca atgccgaact gtccaaactc caacaaagct


 


251
acccccattc catttccgcc gcccaagcca cgctgatggc ggcggcaacc


 


301
gaatttgacg cgcagcgtta cgatgttgcc gaaggtcatt tgaaatgggt


 


351
gttgtccaac caaaaagaca gcctgattca ggcgttggcg gcgcagcgtc


 


401
tgggcgttgt gttgttgcaa caaaaaaaat acgatgccgc gcttgccgca


 


451
ctcgacacgc cggttgaggc ggacttcgcc cccctgctga tggaaactaa


 


501
aggcgatgtt tatgccgcac aggaaaaaag ccaggaagcc ttaaaaaact


 


551
acggacaggc tttggaaaaa atgcctcaag attctgtcgg tcgcgaattg


 


601
cttcaaatga aactcgattc gctgaaataa






This corresponds to the amino acid sequence <SEQ ID 1810; ORF 586.ng>:










g586.pep..




1
MAAHLEEQQE LDNFKYFWKT TGKWLFALLI LAALGYLGYT VYQNRAASQN


 


51
QEAAAVLANI VEKAQNKAPQ SEINAELSKL QQSYPHSISA AQATLMAAAT


 


101
EFDAQRYDVA EGHLKWVLSN QKDSLIQALA AQRLGVVLLQ QKKYDAALAA


 


151
LDTPVEADFA PLLMETKGDV YAAQEKSQEA LKNYGQALEK MPQDSVGREL


 


201
LQMKLDSLK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1811>:










m586.seq




1
ATGGCAGCCC ATCTCGAAGA ACAACAAGAG TTAGACAACT TTAAATATTT


 


51
TTGGAAAACC ACGGGCAAAT GGCTGTTTGC CTTGCTGATT TTGGCGGCAC


 


101
TCGGCTACTT GGGATACACG GTTTACCAAA ACCGTAAAGT TTCCCAAAAT


 


151
CAGGAAGCGG CGGCGGTGCT GGCAAACATC GTAGAAAAGG CGCAAAGCAA


 


201
AGCCCCGCAA AGCGAAATCA ATGCCGAATT GACCAAACTC CAACAAAGCT


 


251
ACCCGCATTC CATTTCCGCC GCCCAAGCCA CACTGATGGC GGCGGCAACC


 


301
GAATTTGACG CGCAGCGTTA CGATGTTGCC GAAGGCCATT TGAAATGGGT


 


351
GTTGTCCAAC CAAAAAGACA GCCTGATTCA AGCGTTGGCG GCGCAGCGTC


 


401
TGGGCGTTGT GTTGTTGCAA CAAAAAAAAT ACGATGCCGC GCTTGCCGCG


 


451
CTCGATACGC CGGTTGAAGC GGACTTCGCC CCCCTGCTGA TGGAAACCAA


 


501
AGGCGATGTC TATGCCGCAC AGGGAAAAAG CCAGGAAGCC TTAAAAAACT


 


551
ACGGACAGGC TTTAGAAAAA ATGCCTCAAG ATTCTGTCGG TCGCGAATTG


 


601
GTTCAAATGA AACTTGATTC GCTGAAATAA






This corresponds to the amino acid sequence <SEQ ID 1812; ORF 586>:










m586.pep




1
MAAHLEEQQE LDNFKYFWKT TGKWLFALLI LAALGYLGYT VYQNRKVSQN


 


51
QEAAAVLANI VEKAQSKAPQ SEINAELTKL QQSYPHSISA AQATLMAAAT


 


101
EFDAQRYDVA EGHLKWVLSN QKDSLIQALA AQRLGVVLLQ QKKYDAALAA


 


151
LDTPVEADFA PLLMETKGDV YAAQGKSQEA LKNYGQALEK MPQDSVGREL


 


201
VQMKLDSLK*






m586/g586 97.1% identity in 209 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1813>:










a586.seq




1
ATGGCAGCCC ATTTGGAAGA ACAACAAGAG TTGGACAACT TTAAATATTT


 


51
TTGGAAAACC ACGGGCAAAT GGCTGTTTGC CGTGCTGATT TTGGCGGCAC


 


101
TCGGCTACTT GGGATACACG GTTTACCAAA ACCGTGCGGC TTCCCAAAAT


 


151
CAGGAAGCGG CGGCGGTGCT GGCAAACATC GTGGAAAAGG CGCAAAACAA


 


201
AGCCCCGCAA AGCGAAATCA ATGCCGAATT GGCCAAGCTC CAACAAAGCT


 


251
ACCCCCATTC CATTTCCGCC GCCCAAGCCA CGCTGATGGC GGCAGCAACC


 


301
GAATTTGACG CGCAGCGTTA CGATGTTGCC GAAGGCCATT TGAAATGGGT


 


351
ATTGTCCAAC CAAAAAGACA GCCTGATCCA GGCGTTGGCG GCGCAGCGTC


 


401
TGGGCGTTGT GTTGTTGCAA CAAAAAAAAT ACGATGCCGC GCTTGCCGCA


 


451
CTCGACACGC CGGTTGAAGC GGACTTCGCC CCCCTGCTGA TGGAAACCAA


 


501
AGGCGATGTC TATGCCGCAC AGGGAAAAAG CCAGGAAGCC TTAAAAAACT


 


551
ACGGACAGGC TTTAGAAAAA ATGCCTCAAG ATTCTGTCGG TCGCGAATTG


 


601
GTTCAAATGA AACTTGATTC GCTGAAATAA






This corresponds to the amino acid sequence <SEQ ID 1814; ORF 586.a>:










a586.pep




1
MAAHLEEQQE LDNFKYFWKT TGKWLFAVLI LAALGYLGYT VYQNRAASQN


 


51
QEAAAVLANI VEKAQNKAPQ SEINAELAKL QQSYPHSISA AQATLMAAAT


 


101
EFDAQRYDVA EGHLKWVLSN QKDSLIQALA AQRLGVVLLQ QKKYDAALAA


 


151
LDTPVEADFA PLLMETKGDV YAAQGKSQEA LKNYGQALEK MPQDSVGREL


 


201
VQMKLDSLK*






m586/a586 97.6% identity in 209 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1815>:










g587.seq..




1
atgaaacgta tctttttgcc cgccttgccc gccatcctgc ctttatccgc


 


51
ttatgccgac ctgcccttga cgattgaaga cataatgacc gacaagggaa


 


101
aatggaaact ggaaacttcc cttacctatc tgaatagcga aaacagccgc


 


151
gccgcacttg ccgcaccggt ttacattcaa accggcgcaa cctcgtttat


 


201
ccccattccg accgaaattc aagaaaacgg cagcaatacc gatatgctcg


 


251
ccggcacgct cggtttgcgc tacggactga ccggcaatac cgacatttac


 


301
ggcagcggca gctatctgtg gcacgaagaa cgcaaactcg acggcaacgg


 


351
caaaacccgc aacaaacgga tgtccgacat atccgccggc atcagccaca


 


401
ccttccttaa agacggcaaa aaccccgccc taatcagctt tcttgaaagc


 


451
acggtttacg aaaaatcgcg caacaaagcc tcgttaatca aaaaaagggg


 


501
gctttgcccc ttttataact taaggataaa ttatgaatat taa






This corresponds to the amino acid sequence <SEQ ID 1816; ORF 587.ng>:










g587.pep..




1
MKRIFLPALP AILPLSAYAD LPLTIEDIMT DKGKWKLETS LTYLNSENSR


 


51
AALAAPVYIQ TGATSFIPIP TEIQENGSNT DMLAGTLGLR YGLTGNTDIY


 


101
GSGSYLWHEE RKLDGNGKTR NKRMSDISAG ISHTFLKDGK NPALISFLES


 


151
TVYEKSRNKA SLIKKRGLCP FYNLRINYEY *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1817>:










m587.seq..




1
ATGAAGCGCA TCTTTTTGCC CGCCTTGCCC GCCATCCTGC CTTTATCCAC


 


51
TTATGCCGAC CTGCCCTTGA CGATTGAAGA CATAATGACC GACAAGGGAA


 


101
AATGGAAACT GGAAACTTCC CTTACCTACC TGAACAGCGA AAACAACCGC


 


151
GCCGAACTTG CCGCACCGGT TTACATTCAA ACCGGCGCAA CCTCGTTTAT


 


201
CCCCATTCCG ACCGAAATCC AAGAAAACGG CAGCAATACC GATATGCTCG


 


251
TCGGCACGCT CGGTTTGCGC TACGGACTGA CCGGGAATAC CGACATTTAC


 


301
GGCAGCGGCA GCTATCTGTG GCACGAAGAA CGCAAACTCG ACGGCAACAG


 


351
CAAAACCCGC AACAAACGGA TGTCCGACGT ATCCCTCGGC ATCAGCCACA


 


401
CTTTCCTTAA AGACGACAAA AACCCCGCCC TAATCAGCTT TCTTGAAAGC


 


451
ACGGTTTACG AAAAATCGCG CAACAAAGCC TCGTCGGGAA AATCCTGGCT


 


501
CATCGGCGCC ACCACCTACA AAGCCATAGA TCCGATTGTC CTTTCCTTCA


 


551
CCGCCGCCTA CCGCATCAAC GGCAGCAAAA CCCTTTCAGA CGGCATCCGC


 


601
TACAAATCGG GCAACTACCT GCTGCTCAAC CCCAACATCT CATTTGCTGC


 


651
CAACGACAGA ATCAGCCTGA CCGGAGGCAT CCAATGGCTG GGCAGGCAGC


 


701
CCGACCGGAC GGACGGCAAA CGGGAATCCT CCAGAAACAC ATCCACCTAC


 


751
GCCCATTTCG GCGCAGGTTT CGGTTTCACC AAAACCACGG CTTTAAACGC


 


801
ATCCGCACGT TTCAACGTTT CAGGGCAAAG CAGTTCCGAA CTGAAATTTG


 


851
GCGTACAGCA TACATTTTAA






This corresponds to the amino acid sequence <SEQ ID 1818; ORF 587>:










m587.pep..




1
MKRIFLPALP AILPLSTYAD LPLTIEDIMT DKGKWKLETS LTYLNSENNR


 


51
AELAAPVYIQ TGATSFIPIP TEIQENGSNT DMLVGTLGLR YGLTGNTDIY


 


101
GSGSYLWHEE RKLDGNSKTR NKRMSDVSLG ISHTFLKDDK NPALISFLES


 


151
TVYEKSRNKA SSGKSWLIGA TTYKAIDPIV LSLTAAYRIN GSKTLSDGIR


 


201
YKSGNYLLLN PNISFAANDR ISLTGGIQWL GRQPDRTDGK RESSRNTSTY


 


251
AHFGAGFGFT KTTALNASAR FNVSGQSSSE LKFGVQHTF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m587/g587 95.0% identity in 161 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1819>:










a587.seq




1
ATGAAGCGCA TCTTTTTGCC CGCCTTGCCC GCCATCCTGC CTTTATCCGC


 


51
TTATGCCGAC CTGCCCTTGA CGATTGAAGA CATAATGACC GACAAGGGCA


 


101
AATGGAAACT GGAAACTTCC CTTACCTACC TGAACAGCGA AAACAACCGC


 


151
GCCGAACTTG CCGCACCGGT TTACATCCAA ACCGGCGCAA CCTCGTTTAT


 


201
CCCCATTCCG ACCGAAATCC AAGAAAACGG CAGCAATACC GATATGCTCG


 


251
TTGGCACGCT CGGTTTGCGC TACGGACTGA CCGGGAATAC CGACATTTAC


 


301
GGCAGCGGCA GCTATCTGTG GCACGAAGAA CGCAAACTCG ACGGCAACGG


 


351
CAAAACCCGA AACAAACGGA TGTCCGACGT ATCCCTCGGC ATCAGCCACA


 


401
CCTTCCTTAA AGACGACAAA AACCCCGCCC TAATCAGCTT TCTTGAAAGC


 


451
ACGGTTTACG AAAAATCGCG CAACAAAGCC TCGTCGGGAA AATCCTGGCT


 


501
CATCGGCGCC ACCACCTACA AAGCCATCGA CCCCGTCGTC CTCTCATTGA


 


551
CCGCTGCCTA CCGTATCAAC GGCAGCAAAA CCCTTTCAAG CAACACCAAA


 


601
TACAAAGCAG GCAATTACTG GATGCTGAAT CCCAATATAT CCTTCGCCGC


 


651
CAACGACAGA ATCAGCCTCA CGGGCGGCAT CCAATGGCTG GGCAAGCAGC


 


701
CCGACCGTCT GGACGGCAAA AAAGAATCCG CAAGAAACAC ATCCACCTAT


 


751
GCCCATTTCG GCGCAGGTTT CGGTTTCACC AAAACCACGG CTTTAAACGC


 


801
ATCCGCACGT TTCAACGTTT CAGGGCAAAG CAGTTCCGAA CTGAAATTTG


 


851
GCGTACAGCA TACGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 1820; ORF 587.a>:










a587.pep




1
MKRIFLPALP AILPLSAYAD LPLTIEDIMT DKGKWKLETS LTYLNSENNR


 


51
AELAAPVYIQ TGATSFIPIP TEIQENGSNT DMLVGTLGLR YGLTGNTDIY


 


101
GSGSYLWHEE RKLDGNGKTR NKRMSDVSLG ISHTFLKDDK NPALISFLES


 


151
TVYEKSRNKA SSGKSWLIGA TTYKAIDPVV LSLTAAYRIN GSKTLSSNTK


 


201
YKAGNYWMLN PNISFAANDR ISLTGGIQWL GKQPDRLDGK KESARNTSTY


 


251
AHFGAGFGFT KTTALNASAR FNVSGQSSSE LKFGVQHTF*






m587/a587 95.2% identity in 289 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1821>:










g588.seq




1
atgcttaaac atctcgcatt cctactgccc gccatgatgt tcgccctccc


 


51
cgcccagacc gccgtcctaa gcccctatca ggaaaccggc tgcacctacg


 


101
aaggcgggat cggaaaagac gggcttcctt caggcaaagg catatggcgt


 


151
tgccgggatg ggcgcggtta taccggttca ttcaaaaacg gcaaattcga


 


201
cgggcaaggc gtttataccg ttgccgccgg ccgcgaagta tttctcgagc


 


251
cgttcaattc cgacagtacc aaattccgca atatggcatt gtcgggcacg


 


301
ttcaaacaag gcttggcaca cggcaggttc gccgcctcgc aaaacggcga


 


351
aaccctcttt tattatgaaa tgcgaacacg gcatgattaa






This corresponds to the amino acid sequence <SEQ ID 1822; ORF 588.ng>:










g588.pep..




1
MLKHLAFLLP AMMFALPAQT AVLSPYQETG CTYEGGIGKD GLPSGKGIWR


 


51
CRDGRGYTGS FKNGKFDGQG VYTVAAGREV FLEPFNSDST KFRNMALSGT


 


101
FKQGLAHGRF AASQNGETLF YYEMRTRHD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1823>:










m588.seq..




1
ATGCTTAAAC ATCTCGCATT CCTACTGCCC GCCATGATGT TCGCCCTCCC


 


51
CACTTCGGCC GCCGTCCTGA CTTCCTATCA AGAACCAGGC TGCACCTACG


 


101
ACGGCAATGT CGGCAAAGAC GGTAAACCCG CCGGCAAAGG CACATGGCGC


 


151
TGCCAAGACG GGCGCAACTA TACCGGTTCG TTTAAAAACG GCAAATTCGA


 


201
CGGGCAAGGC GTTTATACCG TTGCCGCCAA CCGCGAAATA TTTATCGAAC


 


251
CGTTCAATTC CGACAGTACC AAATTCCGCA ACATGGTACT CTCGGGCACG


 


301
TTCAAAAAAG GCTTGGCACA CGGCAGATTT ACCGTCTCGC AAAACGGCGA


 


351
AACCCTCTTC ATTATGAAAT GCGAAAACGG CATGATTAAA GAAGTGAAAC


 


401
TGCCCAAAAA CAAATAA






This corresponds to the amino acid sequence <SEQ ID 1824; ORF 588>:










m588.pep..




1
MLKHLAFLLP AMMFALPTSA AVLTSYQEPG CTYDGNVGKD GKPAGKGTWR


 


51
CQDGRNYTGS FKNGKFDGQG VYTVAANREI FIEPFNSDST KFRNMVLSGT


 


101
FKKGLAHGRF TVSQNGETLF IMKCENGMIK EVKLPKNK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m588/g588 82.5% identity in 120 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1825>:










a588.seq




1
ATGCTTAAAC ATCTCGCATT CCTACTGCCC GCCATGATGT TCGCCCTCCC


 


51
CGCCGCGTCC GCCGTTCTGA CTTCCTATCA AGAACCCGGC TGCACCTACG


 


101
AAGGCGATGT CGGCAAAGAC GGTAAACCCG CCGGCAAAGG CACATGGCGC


 


151
TGCCAAGACG GGCGCAACTA TACCGGTTCG TTTAAAAATG GCAAATTCGA


 


201
CGGACAAGGC GTTTATACCG TTGCCGCCAA CCGCGAAATA TTTATCGAAC


 


251
CGTTCAATTC CGACAGTACC AAATTCCGCA ACATGGTACT CTCGGGCACA


 


301
TTCAAAAAAG GCTTGGCACA CGGCAGATTT ACCGTCTCGC AAAACGGCGA


 


351
AACCCTCTTC ATTATGAAAT GCGAAAACGG CATGATTAAA GAAGTGAAGC


 


401
TGCCCAAAAA CAAATAA






This corresponds to the amino acid sequence <SEQ ID 1826; ORF 588.a>:










a588.pep




1
MLKHLAFLLP AMMFALPAAS AVLTSYQEPG CTYEGDVGKD GKPAGKGTWR


 


51
CQDGRNYTGS FKNGKFDGQG VYTVAANREI FIEPFNSDST KFRNMVLSGT


 


101
FKKGLAHGRF TVSQNGETLF IMKCENGMIK EVKLPKNK*






m588/a588 96.4% identity in 138 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1827>:










g589.seq..




1
atgcaacaaa aaatccgttt ccaaatcgag gcgatgacct gtcaggcatg


 


51
tgcttcgcgc attgaaaaag tgttgaacaa aaaagatttt gtcgaatcgg


 


101
cgggagtgaa ctttgccagt gaggaagcgc aggttacgtt tgacggcagc


 


151
aaaacctcgg ttgccgacat tgccaaaatc attgagaaaa ccggttacgg


 


201
cgcgaaggaa aaaacggaag atacattgcc gcaacctgaa gcagaacacc


 


251
atatcggctg gcggttgtgg cttttgctga ccatcaatat cccgttcctt


 


301
atcggtatgg tagggatgat gctaaaaggg ctgaattgga cacggcacga


 


351
ttggatgatt ccgcctgtat ggcagtttgt actggcaagc atagtgcaac


 


401
tttggctggc aatcccgttt tacaaaagcg cgtgggcaag cattaaaggc


 


451
gggctggcga atatggacgt actcgttacc atcggcacgg tgtcgattta


 


501
cctgtattcc gtttatatgc tgtttttcag ttcgcatgcg gcgcacggta


 


551
tggcgcatgt gtattttgaa gcgggcgtga tggtgatcgg ttttgtgtcg


 


601
ctgggtaagt ttttggaaca ccgcaccaaa aaatccagcc tgaacagctt


 


651
gggcttactg ctaaaactca cgccgaccca agtcaacgtg caacgcaacg


 


701
gcgaatggaa acaactgccc atcgaccaag tgcaaatcgg cgaccttatc


 


751
cgcaccaacc acggcgaacg catcgctgcc gacggcatta tcgaaagcgg


 


801
cagcggttgg gcggacgaaa gccaccttac cggcgaatcc aatcccgaag


 


851
agaaaaaggc gggcggcaaa gtgttggcgg gcgcgctgat gaccgaaggc


 


901
agcgtggtgt accgcgccgc gcagctcggc agccaaaccc tgctcggcga


 


951
catgatgaac gcgctctctg aagcacaagg cagtaaagca ccgattgcgc


 


1001
gcgtggccga taaagcggcg gcggtatttg tgccaactgt cgtgggcatc


 


1051
gcgcttctga cttttatcgt tgcttggctg attaagggcg attggacggt


 


1101
cgcactgatg cacgccgttg ccgttttggt gattgcctgc ccgtgcgcgc


 


1151
tcggtctggc gacccctgcc gcgattatgg tcggcatggg caaagcggtg


 


1201
aaacacggca tttggtttaa agacgcggcg gcaatggagg aagcagccca


 


1251
cgtcgatgcc gtcgtattgg acaaaaccgg tacgctgacc gaaggcaggc


 


1301
cgcaggttgc cgccgtttat tacgttcccg acagcggctt tgacgaagac


 


1351
gctttgtacc gcatcgccgc cgccgtcgag caaaacgccg cccacccgct


 


1401
cgcccgcgcc atcgtctccg ccgcacaagc gcgcggtttg gagattcccg


 


1451
ctgcacaaaa tgcgcaaacc gttgtcggag caggcattac cgccgaagtg


 


1501
gaaggcgtgg gtttggtgaa atcaggcaaa gccgaatttg ccgaactgac


 


1551
cttgccgaag ttttcagacg gcgtttggga aatcgccagt gcggttaccg


 


1601
tatctgtaaa cggcaaaccg atcggcgcat tcgcactctc cgacgcgttg


 


1651
aaagccgata ccgccgaagc cataggccgt ctgaaaaaac acaatatcga


 


1701
tgtctatatt atgagcggcg ataaccaaag tacggtcgaa tacgtcgcca


 


1751
aacaactggg catcgcacac gccttcggta atatgagtcc gtgcgacaaa


 


1801
gccgccgaag tgcagaaact caaagccgcc ggcaaaaccg tggcgatggt


 


1851
cggcgacggc atcaacgacg cgcccgcgct tgccgccgcc aacgtcagct


 


1901
tcgccatgaa aggcggtgcg gacgttgccg aacacaccgc ctccgccacg


 


1951
ctgatgcagc attcggtcaa tcagctcgcc gatgccctgc tgatatcgca


 


2001
ggcaacgttg gaaaacatca agcaaaacct atttttcgcc ttcttctaca


 


2051
atatattggg cattccgctc gccgcgctcg gctttttaaa tcccgtcata


 


2101
gcaggcgcgg caatggcggc aagctcggtt tcggtattgg gcaatgccct


 


2151
gcgcctgaaa tgggtaaaaa tcgattga






This corresponds to the amino acid sequence <SEQ ID 1828; ORF 589.ng>:










g589.pep..




1
MQQKIRFQIE AMTCQACASR IEKVLNKKDF VESAGVNFAS EEAQVTFDGS


 


51
KTSVADIAKI IEKTGYGAKE KTEDTLPQPE AEHHIGWRLW LLLTINIPFL


 


101
IGMVGMMLKG LNWTRHDWMI PPVWQFVLAS IVQLWLAIPF YKSAWASIKG


 


151
GLANMDVLVT IGTVSIYLYS VYMLFFSSHA AHGMAHVYFE AGVMVIGFVS


 


201
LGKFLEHRTK KSSLNSLGLL LKLTPTQVNV QRNGEWKQLP IDQVQIGDLI


 


251
RTNHGERIAA DGIIESGSGW ADESHLTGES NPEEKKAGGK VLAGALMTEG


 


301
SVVYRAAQLG SQTLLGDMMN ALSEAQGSKA PIARVADKAA AVFVPTVVGI


 


351
ALLTFIVAWL IKGDWTVALM HAVAVLVIAC PCALGLATPA AIMVGMGKAV


 


401
KHGIWFKDAA AMEEAAHVDA VVLDKTGTLT EGRPQVAAVY YVPDSGFDED


 


451
ALYRIAAAVE QNAAHPLARA IVSAAQARGL EIPAAQNAQT VVGAGITAEV


 


501
EGVGLVKSGK AEFAELTLPK FSDGVWEIAS AVTVSVNGKP IGAFALSDAL


 


551
KADTAEAIGR LKKHNIDVYI MSGDNQSTVE YVAKQLGIAH AFGNMSPCDK


 


601
AAEVQKLKAA GKTVAMVGDG INDAPALAAA NVSFAMKGGA DVAEHTASAT


 


651
LMQHSVNQLA DALLISQATL ENIKQNLFFA FFYNILGIPL AALGFLNPVI


 


701
AGAAMAASSV SVLGNALRLK WVKID*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1829>:










m589.seq..




1
ATGCAACAAA AAATCCGTTT CCAAATCGAA GGCATGACCT GCCAGGCCTG


 


51
CGCTTCGCGC ATTGAAAAAG TGTTGAACAA AAAAGATTTT GTCGAATCGG


 


101
CGGGGGTAAA CTTCGCCAGC GAAGAGGCGC AGGTAGTGTT TGACGACAGC


 


151
AAAACCTCAG TAGCCGACAT TGCCAAAATC ATTGAGAAAA CCGGTTACGG


 


201
CGCGAAGGAA AAAACGGAAG ATACATTGCC GCAACCCGAA GCAGAACACC


 


251
ATATCGGCTG GCGGCTGTGG CTGCTGTTCA CCATCAACGT CCCGTTCCTT


 


301
ATCGGCATGG CGGGGATGAT GATCGGCAGA CACGATTGGA TGATTCCGCC


 


351
GTTGTGGCAG TTCGCATTGG CAAGCGTGGT GCAGCTTTGG CTGGCAATCC


 


401
CGTTTTACAA AAGCGCGTGG GCGAGCATTA AGGGCGGACT GGCGAATATG


 


451
GACGTGCTGG TTACCATCGG CACGGTCTCG ATTTACCTGT ATTCCGTCTA


 


501
TATGCTGTTT TTCAGCCCGC ACGCGGCGTA CGGTATGGCG CATGTGTATT


 


551
TTGAAGTGGG CGTGATGGTG ATCGGTTTTG TGTCACTGGG TAAATTTTTG


 


601
GAACACCGTA CCAAAAAATC CAGCCTCAAC AGCTTGGGCT TGCTGCTCAA


 


651
ACTTACACCA ACCCAAGTCA ACGTGCAACG CAACGGCGAA TGGAAACAGC


 


701
TTCCCATCGA CCAAGTGCAA ATCGGCGACC TTATCCGCGC CAACCACGGC


 


751
GAACGCATTG CCGCAGACGG CATCATTGAA AGCGGCAGCG GTTGGGCGGA


 


801
CGAGAGCCAT CTTACCGGCG AATCCAATCC TGAAGAAAAA AAGGCGGGCG


 


851
GCAAAGTGTT GGCGGGCGCG TTAATGACCG AAGGCAGTGT GGTGTACCGC


 


901
GCCACGCAGC TCGGCAGCCA AACCCAGCTC GGCGACATGA TGAACGCGCT


 


951
CTCTGAAGCA CAAGGCAGTA AAGCACCGAT TGCGCGCGTA GCCGATAAAG


 


1001
CGGCTGCGGT ATTCGTGCCT GCCGTCGTGG GCATTGCGTT GTTGACTTTT


 


1051
ATTGTTACTT GGCTGATTAA GGGCGATTGG ACGGTTGCGC TGATGCACGC


 


1101
CGTCGCCGTT TTGGTGATTG CCTGCCCGTG CGCGCTGGGT CTGGCAACCC


 


1151
CTGCCGCGAT TATGGTCGGT ATGGGCAAAG CGGTTAAACA CGGTATTTGG


 


1201
TTTAAAGACG CGGCAGCAAT GGAGGAAGCC GCCCACGTCG ATGCCGTCGT


 


1251
GTTGGACAAA ACCGGTACGC TGACCGAAGG CAGCCCGCAG GTTGCCGCCG


 


1301
TTTATTGCGT TCCCGACAGC GGCTTTGACG AAGACGCTTT GTACCGCATC


 


1351
GCCGCCGCCG TCGAACAAAA CGCCGCCCAT CCGCTCGCCC GTGCCATCGT


 


1401
CTCCGCCGCC CAAGCGCGCG GTTTGGACAT TCCCGCCGCA CAAAACGCAC


 


1451
AAACCGTTGT CGGCGCAGGC ATTACCGCCG AAGTGGAAGG CGTGGGTTTG


 


1501
GTGAAAGCAG GCAAAGCCGA ATTTGCCGAA CTGGCCTTGC CGAAGTTTTT


 


1551
AGACGGCGTT TGGGATATTG CAAGCATTGT TGCGGTCTCA GTCGATAACA


 


1601
AACCCATCGG CGCATTCGCA CTTGCCGACG CGTTGAAAGC CGATACCGCC


 


1651
GAAGCCATAG GCCGTCTGAA AAAACACAAT ATCGATGTCT ATATTATGAG


 


1701
CGGCGACAAC CAAGGCACGG TCGAATACGT CGCCAAACAA CTGGGCATCG


 


1751
CACACGCCTT CGGCAACATG AGTCCGCGCG ATAAAGCTGC CGAAGTGCAA


 


1801
AAACTCAAAG CCGCCGGCAA AACCGTGGCG ATGGTCGGCG ACGGCATCAA


 


1851
CGACGCGCCC GCGCTTGCCG CCGCTAACGT CAGCTTCGCC ATGAAAGGCG


 


1901
GAGCGGACGT TGCCGAACAT ACCGCATCCG CCACGCTGAT GCAGCATTCG


 


1951
GTCAACCAAC TCGCCGATGC TCTGCTGGTG TCGCAAGCCA CTTTGAAAAA


 


2001
CATCAAGCAA AACCTGTTTT TCGCCTTCTT CTACAATATT TTGGGCATTC


 


2051
CTCTCGCCGC GCTTGGCTTT TTAAATCCCG TCATCGCTGG CGCGGCAATG


 


2101
GCGGCAAGCT CGGTTTCCGT GTTGAGCAAT GCCTTGCGCC TGAAACGGGT


 


2151
AAAAATCGAT TAG






This corresponds to the amino acid sequence <SEQ ID 1830; ORF 589>:










m589.pep..




1
MQQKIRFQIE GMTCQACASR IEKVLNKKDF VESAGVNFAS EEAQVVFDDS


 


51
KTSVADIAKI IEKTGYGAKE KTEDTLPQPE AEHHIGWRLW LLFTINVPFL


 


101
IGMAGMMIGR HDWMIPPLWQ FALASVVQLW LAIPFYKSAW ASIKGGLANM


 


151
DVLVTIGTVS IYLYSVYMLF FSPHAAYGMA HVYFEVGVMV IGFVSLGKFL


 


201
EHRTKKSSLN SLGLLLKLTP TQVNVQRNGE WKQLPIDQVQ IGDLIRANHG


 


251
ERIAADGIIE SGSGWADESH LTGESNPEEK KAGGKVLAGA LMTEGSVVYR


 


301
ATQLGSQTQL GDMMNALSEA QGSKAPIARV ADKAAAVFVP AVVGIALLTF


 


351
IVTWLIKGDW TVALMHAVAV LVIACPCALG LATPAAIMVG MGKAVKHGIW


 


401
FKDAAAMEEA AHVDAVVLDK TGTLTEGSPQ VAAVYCVPDS GFDEDALYRI


 


451
AAAVEQNAAH PLARAIVSAA QARGLDIPAA QNAQTVVGAG ITAEVEGVGL


 


501
VKAGKAEFAE LALPKFLDGV WDIASIVAVS VDNKPIGAFA LADALKADTA


 


551
EAIGRLKKHN IDVYIMSGDN QGTVEYVAKQ LGIAHAFGNM SPRDKAAEVQ


 


601
KLKAAGKTVA MVGDGINDAP ALAAANVSFA MKGGADVAEH TASATLMQHS


 


651
VNQLADALLV SQATLKNIKQ NLFFAFFYNI LGIPLAALGF LNPVIAGAAM


 


701
AASSVSVLSN ALRLKRVKID *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m589/g589 94.2% identity in 725 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1831>:










a589.seq




1
ATGCAACAAA AAGTCCGTTT CCAAATCGAA GGCATGACCT GCCAGGCATG


 


51
TGCTTCGCGC ATTGAAAAAG TGTTGAACAA AAAAGATTTT GTCGAATCGG


 


101
CGGGGGTAAA CTTCGCCAGC GAAGAGGCTC AGGTAGTGTT TGACGACAGC


 


151
AAAACCTCAG TAGCCGACAT TGCCAAAATC ATTGAGAAAA CCGGTTACGG


 


201
CGCGAAGGAA AAAACGGAAG ATACATTGCC GCAACCCGAA GCAGAACACC


 


251
ATATCGGCTG GAGGTTGTGG CTTTTGCTGG CCATCAATAT CCCGTTCCTT


 


301
ATCGGTATGG TAGGGATGAT GCTAAAAGGG CTGAATTGGA CACGGCATGA


 


351
TTGGATGTTG TCGCCCTTGT TGCAGTTTGC ATTGGCGAGT GTGGTGCAGC


 


401
TTTGGCTGGC GGTGCCATTT TACAAAAGCG CGTGGGCGAG CATTAAAGGC


 


451
GGGCTGGCGA ATATGGACGT ACTCGTTACC ATCGGCACGG TCTCGATTTA


 


501
CCTGTATTCC GTCTATATGC TGTTTTTCAG CCCGCACGCG GCGTACGGTA


 


551
TGGCGCATGT GTATTTTGAA GTAGGCATAA TGGTGATTGG TTTTGTGTCA


 


601
CTGGGTAAAT TTTTGGAACA CCGCACCAAA AAATCCAGCC TGAACAGCTT


 


651
GGGCTTGCTG CTCAAACTCA CGCCAACCCA AGTCAACGTG CAACGCGATG


 


701
GCGAATGGCG GCAGCTACCC ATCGACCAAG TGCAAATCGG CGACCTAATC


 


751
CGCGCCAATC ACGGCGAACG CATTGCCGCC GACGGCATCA TAGAAAGCGG


 


801
CAGCGGCTGG GCGGACGAAA GCCATCTTAC CGGCGAATCC AATCCCGAAG


 


851
AGAAAAAGGC AGGCGGCAAA GTATTGGCGG GCGCGCTGAT GACTGAAGGC


 


901
AGCGTGGTGT ACCGCGCCGC GCAGCTCGGC AGCCAAACCC TGCTCGGCGA


 


951
CATGATGAAC GCGCTCTCCG AAGCGCAAGG CAGTAAAGCA CCGATTGCGC


 


1001
GTGTGGCGGA CAAGGCGGCG GCGGTATTCG TGCCTGCCGT TGTGGGCATC


 


1051
GCACTTTTGA CTTTTATCGC TACTTGGCTG ATTAAGGGCG ATTGGACGCT


 


1101
CGCATTGATG CACGCCGTCG CCGTTTTGGT GATTGCCTGC CCGTGTGCAC


 


1151
TCGGTTTGGC AACCCCTGCT GCGATTATGG TCGGTATGGG CAAAGCGGTT


 


1201
AAACACGGTA TTTGGTTTAA AGACGCGGCA GCAATGGAAG AAGCCGCCCA


 


1251
CGTTGATGCC GTCGTGCTGG ACAAAACCGG CACGCTGACC GAAGGCAAGC


 


1301
CGCAGGTTGC CGCCGTTTAT TGTGTTCCCG ACAGCGGCTT TGACGAAGAC


 


1351
GCTTTGTACC GCATCGCCGC CGCCGTCGAA CAAAACGCCG CCCATCCGCT


 


1401
CGCCCGTGCC ATCGTCTCCG CCGCCCAGGC GCGCGGTTTG GAGATTCCCA


 


1451
CCGCACAAAA TGCCCAAACC ATTGTCGGCG CGGGCATTAC CGCCGAAGTA


 


1501
AAAGGCGCGG GTTTGGTAAA AGCAGGCAAA GCCGAATTTG CCGAACTGAC


 


1551
CTTGCCGAAG TTTTCAGACG GCGTTTGGGA AATCGCCAGT GTGGTTGCCG


 


1601
TATCTGTAAA CGGCAAACCT ATCGGCGCAT TCGCACTCGC CGACGCGTTG


 


1651
AAAGCCGATA CCGCCGAAGC CATAGGCCGT CTGAAAAAAC ACAATATCGA


 


1701
TGTCTATATT ATGAGCGGCG ATAACCAAGG CACGGTCGAG TACGTCGCCA


 


1751
AACAACTGGG CATCGCACAC GCCTTCGGTA ATATGAGTCC GCGCGACAAA


 


1801
GCCGCCGAAG TGCAGAAACT CAAAGCCGCC GGCAAAACCG TGGCGATGGT


 


1851
CGGCGACGGC ATCAACGACG CGCCCGCGCT CGCCGCCGCC AACGTCAGCT


 


1901
TCGCCATGAA AGGCGGTGCA GACGTTGCCG AACACACCGC ATCCGCCACA


 


1951
CTGATGCAGC ATTCGGTCAA CCAGCTCGCC GATGCGCTAT CGGTATCGCG


 


2001
AGCGACGTTG AAAAACATCA AGCAAAACCT GTTTTTCGCC TTCTTCTACA


 


2051
ATATTTTGGG CATTCCGCTC GCCGCGCTCG GCTTTTTAAA CCCCGTCATC


 


2101
GCAGGCGCGG CAATGGCGGC AAGCTCGGTT TCCGTGTTGA GCAACGCCTT


 


2151
GCGCCTGAAA CGGGTAAAAA TCGATTGA






This corresponds to the amino acid sequence <SEQ ID 1832; ORF 589.a>:










a589.pep




1
MQQKVRFQIE GMTCQACASR IEKVLNKKDF VESAGVNFAS EEAQVVFDDS


 


51
KTSVADIAKI IEKTGYGAKE KTEDTLPQPE AEHHIGWRLW LLLAINIPFL


 


101
IGMVGMMLKG LNWTRHDWML SPLLQFALAS VVQLWLAVPF YKSAWASIKG


 


151
GLANMDVLVT IGTVSIYLYS VYMLFFSPHA AYGMAHVYFE VGIMVIGFVS


 


201
LGKFLEHRTK KSSLNSLGLL LKLTPTQVNV QRDGEWRQLP IDQVQIGDLI


 


251
RANHGERIAA DGIIESGSGW ADESHLTGES NPEEKKAGGK VLAGALMTEG


 


301
SVVYRAAQLG SQTLLGDMMN ALSEAQGSKA PIARVADKAA AVFVPAVVGI


 


351
ALLTFIATWL IKGDWTLALM HAVAVLVIAC PCALGLATPA AIMVGMGKAV


 


401
KHGIWFKDAA AMEEAAHVDA VVLDKTGTLT EGKPQVAAVY CVPDSGFDED


 


451
ALYRIAAAVE QNAAHPLARA IVSAAQARGL EIPTAQNAQT IVGAGITAEV


 


501
KGAGLVKAGK AEFAELTLPK FSDGVWEIAS VVAVSVNGKP IGAFALADAL


 


551
KADTAEAIGR LKKHNIDVYI MSGDNQGTVE YVAKQLGIAH AFGNMSPRDK


 


601
AAEVQKLKAA GKTVAMVGDG INDAPALAAA NVSFAMKGGA DVAEHTASAT


 


651
LMQHSVNQLA DALSVSRATL KNIKQNLFFA FFYNILGIPL AALGFLNPVI


 


701
AGAAMAASSV SVLSNALRLK RVKID*






m589/a589 94.9% identity in 725 aa overlap







The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1833>:










g590.seq..




1
atgaaaaaac ctttgatttc agttgcggca gtattgctcg gcgttgcttt


 


51
gggtacacct tattatttgg gtgtcaaagc agaagaaagt ctgacgcagc


 


101
agcaaaaaat attgcagaaa acgggctttt tgaccgtcga atcgcaccag


 


151
tatgatcgag gctggtttac ctctacggaa acgacggtca tccgtctgaa


 


201
acccgagttg ctgcataatg cgcagaaata cctgccggat aacttgaaaa


 


251
tagtgttgga acagccggtt acgctggtaa accatatcac gcacggccct


 


301
ttcgccggcg gattcggcac gcaggcgcac attgaaaccg agttcaaata


 


351
cgcgcctgaa acggaaaaag ttttggaacg cttttttggg aaacaagttc


 


401
cggtttccct tgccaatacc gtttatttca acggcagcgg taaaatggaa


 


451
gtcagtgttc ccgctttcga ttatgaagaa ctgtcgggca tcaggctgca


 


501
ctgggaaggc ctgacggggg aaacggttta tcaaaaaggt ttcaaaagct


 


551
accgcaacag ctatgatgcg cccttgttca aaatcaagct ggcagacaaa


 


601
ggcgatgccg cgtttgaaaa agcgcatttc gattcggaaa cttcagacgg


 


651
catcaatccg cttgctttgg gcagcagcaa tctgactttg gaaaaatttt


 


701
cgctcgaatg gaaagagggt gtcgattaca acgtcaaatt gaacgaactg


 


751
gtcaacctcg ttaccgattt gcagatcggc gcgtttatca atcccaacgg


 


801
cagcatcgca ccttccaaaa tcgaagtcgg caagctggct ttttcaacca


 


851
agaccgggga atcgggcgcg tttatcgaca gcgaagggcg gttccgtttc


 


901
gatacgttgg tgtacggcga tgaaaaatac ggcccgctgg acatccatat


 


951
cgctgccgaa cacctcgatg cttctgcctt aaccgtattg aaacgcaagt


 


1001
ttgcacaaat ttctgccaaa aaaatgactg aggaacaaat ccgcaatgat


 


1051
ttgattgcgg cagtcaaagg cgatgcttcc ggattattta cccatgaccc


 


1101
ggtactaaat atcaaaattt tccgtttcac cctgcctcag ggaaaaattg


 


1151
atgtgggcgg aaaaatcatg tttaaaggca tgaagaagga agatttgaac


 


1201
caattgggac tgatgttaaa gaaaaccgag gcaaacatca gaatgagtat


 


1251
tcctcaaaaa atgttggaag atttggcggt aagtcaggct ggaaatattt


 


1301
tcagtgtaaa tgccgaagat gaggcggaag ccagagcaag cattgccgat


 


1351
attaatgaaa cattgcgcct gatggtggac agtacggtcc aaagtatggc


 


1401
aagggaaaaa tatcttactt tagacggtaa tcagattgat acggtcattt


 


1451
cccttaaaaa caacgccctg aagttaaacg ggaaaacgct gcaaaatgaa


 


1501
cccgatcctg attttgacga gggagatatg gtttccggcc agccgcatta


 


1551
a






This corresponds to the amino acid sequence <SEQ ID 1834; ORF 590.ng>:










g590.pep..




1
MKKPLISVAA VLLGVALGTP YYLGVKAEES LTQQQKILQK TGFLTVESHQ


 


51
YDRGWFTSTE TTVIRLKPEL LHNAQKYLPD NLKIVLEQPV TLVNHITHGP


 


101
FAGGFGTQAH IETEFKYAPE TEKVLERFFG KQVPVSLANT VYFNGSGKME


 


151
VSVPAFDYEE LSGIRLHWEG LTGETVYQKG FKSYRNSYDA PLFKIKLADK


 


201
GDAAFEKAHF DSETSDGINP LALGSSNLTL EKFSLEWKEG VDYNVKLNEL


 


251
VNLVTDLQIG AFINPNGSIA PSKIEVGKLA FSTKTGESGA FIDSEGRFRF


 


301
DTLVYGDEKY GPLDIHIAAE HLDASALTVL KRKFAQISAK KMTEEQIRND


 


351
LIAAVKGDAS GLFTHDPVLN IKIFRFTLPQ GKIDVGGKIM FKGMKKEDLN


 


401
QLGLMLKKTE ANIRMSIPQK MLEDLAVSQA GNIFSVNAED EAEARASIAD


 


451
INETLRLMVD STVQSMAREK YLTLDGNQID TVISLKNNAL KLNGKTLQNE


 


501
PDPDFDEGDM VSGQPH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1835>:









m590.seq (partial) ..










1
..TGGTTTACCT CTATGGAAAC GACGGTCATC CGTCTGAAAC CCGAGTTGCT



 


51
  GAATAATGCC CGAAAATACC TGCCGGATAA CCTGAAAACA GTGTTGGAAC


 


101
  AGCCGGTTAC GCTGGTTAAC CATATCACGC ACGGCCCTTT CGCCGGCGGA


 


151
  TTCGGCACGC AGGCGTACAT TGAAACCGAG TTCAAATACG CGCCTGAAAC


 


201
  GGAAAAAGTT CTGGAACGCT TTTTTGGAAA ACAAGTCCCG GCTTCCCTTG


 


251
  CCAATACCGT TTATTTTAAC GGCAGCGGTA AAATGGAAGT CAGTGTTCCC


 


301
  GCCTTCGATT ATGAAGAGCT GTCGGGCATc AG.CTGCACT GGGAAkGCCT


 


351
  GACGGGAGAA ACGGTTTATC AAAAAGGTTT CAAAAGCTAC CGGAACGGCT


 


401
  ATGATGCCCC CTTGTTTAAA ATCAAGCTGG CAGACAAAGG CGATGCCGCG


 


451
  TTTGAAAAAG TGCATTTCGA TTCGGAAACT TCAGACGGCA TCAATCCGCT


 


501
  TGCTTTGGGC AGCAGCAATC TGACCTTGGA AAAATTCTCC CTAGAATGGA


 


551
  AAGAGGGTGT CGATTACAAC GTCAAGTTAA ACGAACTGGT CAATCTTGTT


 


601
  ACCGATTTGC AGATTGGCGC GTTTATCAAT CCCAACGGCA GCATCGCACC


 


651
  TTCCAAAATC GAAGTCGGCA AACTGGCTTT TTCAACCAAG ACCGGGGAAT


 


701
  CAGGCGCGTT TATCAACAGT GAAGGGCAGT TCCGTTTCGA TACACTGGTG


 


751
  TACGGCGATG AAAAATACGG CCCGCTGGAC ATCCATATCG CTGCCGAACA


 


801
  CCTCGATGCT TCTGCCTTAA CCGTATTGAA ACGCAAGTTT GCACAAATTT


 


851
  CCGCCAAAAA AATGACCGAG GAACAAATCC GCAATGATTT GATTGCCGCC


 


901
  GTCAAAGGAG AGGCTTCCGG ACTGTTCACC AACAATCCCG TATTGGACAT


 


951
  TAAAACTTTC CGATTCACGC TGCCATCGGG AAAAATCGAT GTGGGCGGAA


 


1001
  AAATCATGTT TAAAGACATG AAGAAGGAAG ATTTGAATCA ATTGGGTTTG


 


1051
  ATGCTGAAGA AAACCGAAGC CGACATCAGA ATGAGTATTC CCCAAAAAAT


 


1101
  GCTGGAAGAC TTGGCGGTCA GTCAAGCAGG CAATATTTTC AGCGTCAATG


 


1151
  CCGAAGATGA GGCGGAAGGC AGGGCAAGTC TTGACGACAT CAACGAGACC


 


1201
  TTGCGCCTGA TGGTGGACAG TACGGTTCAG AGTATGGCAA GGGAAAAATA


 


1251
  TCTGACTTTG AACGGCGACC AGATTGATAC TGCCATTTCT CTGAAAAACA


 


1301
  ATCAGTTGAA ATTGAACGGT AAAACGTTGC AAAACGAACC GGAGCCGGAT


 


1351
  TTTGATGAAG GCGGTATGGT TTCAGAGCCG CAGCAGTAA






This corresponds to the amino acid sequence <SEQ ID 1836; ORF 590>:









m590.pep.. (partial)










1
..WFTSMETTVI RLKPELLNNA RKYLPDNLKT VLEQPVTLVN HITHGPFAGG



 


51
  FGTQAYIETE FKYAPETEKV LERFFGKQVP ASLANTVYFN GSGKMEVSVP


 


101
  AFDYEELSGI XLHWEXLTGE TVYQKGFKSY RNGYDAPLFK IKLADKGDAA


 


151
  FEKVHFDSET SDGINPLALG SSNLTLEKFS LEWKEGVDYN VKLNELVNLV


 


201
  TDLQIGAFIN PNGSIAPSKI EVGKLAFSTK TGESGAFINS EGQFRFDTLV


 


251
  YGDEKYGPLD IHIAAEHLDA SALTVLKRKF AQISAKKMTE EQIRNDLIAA


 


301
  VKGEASGLFT NNPVLDIKTF RFTLPSGKID VGGKIMFKDM KKEDLNQLGL


 


351
  MLKKTEADIR MSIPQKMLED LAVSQAGNIF SVNAEDEAEG RASLDDINET


 


401
  LRLMVDSTVQ SMAREKYLTL NGDQIDTAIS LKNNQLKLNG KTLQNEPEPD


 


451
  FDEGGMVSEP QQ*






m590/g590 93.1% identity in 462 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1837>:










a590.seq




1
ATGAAAAAAC CTTTGATTTC GGTTGCGGCA GCATTGCTCG GCGTTGCTTT


 


51
GGGCACGCCT TATTATTTGG GTGTCAAAGC CGAAGAAAGC TTGACGCAGC


 


101
AGCAAAAAAT ATTGCAGGAA GCGGGCTTCT TGACCGTCGA ATCGCACCAA


 


151
TATGAGCGCG GCTGGTTTAC CTCTACGGAA ACGACGGTCA TCCGCTTGAA


 


201
ACCCGAGTTG CTGCATAATG CGCAGAAATA CCTGCCGGAT AACCTGAAAA


 


251
CAGTGTTGGA ACAGCCGGTT ACGCTGGTAA ACCATATCAC GCACGGTCCT


 


301
TTTGCCGGCG GATTCGGCAC GCAGGCGTAC ATTGAAACCG AGTTCAAATA


 


351
CGCGCCTGAA ACGGAAAAAG TTCTGGAACG CTTTTTTGGA AAACAAGTCC


 


401
CGGTTTCCCT TGCCAATACC GTTTATTTTA ACGGCAGCGG TAAAATGGAA


 


451
GTCAGTGTTC CCGCCTTCGA TTATGAAGAG CTGTCGGGCA TCAGGCTGCA


 


501
CTGGGAAGGC CTGACGGGAG AAACGGTTTA TCAAAAAGGT TTCAAAAGCT


 


551
ACCGGAACGG CTATGATGCC CCCTTGTTTA AAATCAAGCT GGCAGACAAA


 


601
GGCGATGCCG CGTTTGAAAA AGTGCATTTC GATTCGGAAA CTTCAGACGG


 


651
CATCAACCCG CTTGCTTTGG GCAGCAGCAA TCTGACCTTG GAAAAATTTT


 


701
CCTTAGAATG GAAAGAGGGT GTCGATTACA ACGTCAAGTT AAACGAACTG


 


751
GTCAATCTTG TTACCGATTT GCAGATTGGC GCGTTTATCA ATCCCAACGG


 


801
CAGCATCGCA CCTTCCAAAA TCGAAGTCGG CAAGCTGGCT TTTTCAACCA


 


851
AGACCGGGGA ATCGGGCGCG TTTATCGATA GCGAAGGGCA GTTCCGTTTT


 


901
GGCACGCTGG TTTACGGCGA TGAAAAATAC GGCCCTCTGG ACATCCATAT


 


951
CGCTGCCGAA CACCTCGATG CTTCTGCCTT AACCGTATTG AAACGCAAGT


 


1001
TTGCACGAAT TTCTGCCAAA AAAATGACTG AAGAACAAAT CCGCAATGAT


 


1051
TTGATTGCGG CAGTCAAAGG CGAGGCTTCC GGATTATTTA CCCATAACCC


 


1101
AGTATTGGAC ATTAAAACTT TCCGATTCAC GCTGCCATCG GGAAAAATCG


 


1151
ATGTGGGCGG AAAAATCATG TTTAAAGACA TGAAGAAGGA AGATTTGAAC


 


1201
CAATTGGGTT TGATGCTGAA GAAAACCGAA GCCGACATCA GAATGAGTAT


 


1251
TCCCCAAAAA ATGCTGGAAG ACTTGGCGGT CAGTCAAGCA GGCAATATTT


 


1301
TCAGCGTCAA TGCCGAAGAT GAGGCGGAAG GCAGGGCAAG TCTTGACGAC


 


1351
ATCAACGAGA CCTTGCGCCT GATGGTGGAC AGTACGGTTC AGAGTATGGC


 


1401
AAGGGAAAAA TATCTGACTT TGAACGGCGA CCAGATTGAT ACTGCCATTT


 


1451
CTCTGAAAAA CAATCAGTTG AAATTGAACG GTAAAACGTT GCAAAACGAA


 


1501
CCGGAGCCGG ATTTTGATGA AGGCGGTATG GTTTCAGAGC CGCAGCAGTA


 


1551
A






This corresponds to the amino acid sequence <SEQ ID 1838; ORF 590.a>:










a590.pep




1
MKKPLISVAA ALLGVALGTP YYLGVKAEES LTQQQKILQE AGFLTVESHQ


 


51
YERGWFTSTE TTVIRLKPEL LHNAQKYLPD NLKTVLEQPV TLVNHITHGP


 


101
FAGGFGTQAY IETEFKYAPE TEKVLERFFG KQVPVSLANT VYFNGSGKME


 


151
VSVPAFDYEE LSGIRLHWEG LTGETVYQKG FKSYRNGYDA PLFKIKLADK


 


201
GDAAFEKVHF DSETSDGINP LALGSSNLTL EKFSLEWKEG VDYNVKLNEL


 


251
VNLVTDLQIG AFINPNGSIA PSKIEVGKLA FSTKTGESGA FIDSEGQFRF


 


301
GTLVYGDEKY GPLDIHIAAE HLDASALTVL KRKFARISAK KMTEEQIRND


 


351
LIAAVKGEAS GLFTHNPVLD IKTFRFTLPS GKIDVGGKIM FKDMKKEDLN


 


401
QLGLMLKKTE ADIRMSIPQK MLEDLAVSQA GNIFSVNAED EAEGRASLDD


 


451
INETLRLMVD STVQSMAREK YLTLNGDQID TAISLKNNQL KLNGKTLQNE


 


501
PEPDFDEGGM VSEPQQ*






m590/a590 97.8% identity in 462 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1839>:










m590-1.seq




1
ATGAAAAAAC CTTTGATTTC GGTTGCGGCA GCATTGCTCG GCGTTGCTTT


 


51
GGGCACGCCT TATTATTTGG GTGTCAAAGC CGAAGAAAGC TTGACGCAGC


 


101
AGCAAAAAAT ATTGCAGGAA ACGGGCTTCT TGACCGTCGA ATCGCACCAA


 


151
TATGAGCGCG GCTGGTTTAC CTCTATGGAA ACGACGGTCA TCCGTCTGAA


 


201
ACCCGAGTTG CTGAATAATG CCCGAAAATA CCTGCCGGAT AACCTGAAAA


 


251
CAGTGTTGGA ACAGCCGGTT ACGCTGGTTA ACCATATCAC GCACGGCCCT


 


301
TTCGCCGGCG GATTCGGCAC GCAGGCGTAC ATTGAAACCG AGTTCAAATA


 


351
CGCGCCTGAA ACGGAAAAAG TTCTGGAACG CTTTTTTGGA AAACAAGTCC


 


401
CGGCTTCCCT TGCCAATACC GTTTATTTTA ACGGCAGCGG TAAAATGGAA


 


451
GTCAGTGTTC CCGCCTTCGA TTATGAAGAG CTGTCGGGCA TCAGGCTGCA


 


501
CTGGGAAGGC CTGACGGGAG AAACGGTTTA TCAAAAAGGT TTCAAAAGCT


 


551
ACCGGAACGG CTATGATGCC CCCTTGTTTA AAATCAAGCT GGCAGACAAA


 


601
GGCGATGCCG CGTTTGAAAA AGTGCATTTC GATTCGGAAA CTTCAGACGG


 


651
CATCAATCCG CTTGCTTTGG GCAGCAGCAA TCTGACCTTG GAAAAATTCT


 


701
CCCTAGAATG GAAAGAGGGT GTCGATTACA ACGTCAAGTT AAACGAACTG


 


751
GTCAATCTTG TTACCGATTT GCAGATTGGC GCGTTTATCA ATCCCAACGG


 


801
CAGCATCGCA CCTTCCAAAA TCGAAGTCGG CAAACTGGCT TTTTCAACCA


 


851
AGACCGGGGA ATCAGGCGCG TTTATCAACA GTGAAGGGCA GTTCCGTTTC


 


901
GATACACTGG TGTACGGCGA TGAAAAATAC GGCCCGCTGG ACATCCATAT


 


951
CGCTGCCGAA CACCTCGATG CTTCTGCCTT AACCGTATTG AAACGCAAGT


 


1001
TTGCACAAAT TTCCGCCAAA AAAATGACCG AGGAACAAAT CCGCAATGAT


 


1051
TTGATTGCCG CCGTCAAAGG AGAGGCTTCC GGACTGTTCA CCAACAATCC


 


1101
CGTATTGGAC ATTAAAACTT TCCGATTCAC GCTGCCATCG GGAAAAATCG


 


1151
ATGTGGGCGG AAAAATCATG TTTAAAGACA TGAAGAAGGA AGATTTGAAT


 


1201
CAATTGGGTT TGATGCTGAA GAAAACCGAA GCCGACATCA GAATGAGTAT


 


1251
TCCCCAAAAA ATGCTGGAAG ACTTGGCGGT CAGTCAAGCA GGCAATATTT


 


1301
TCAGCGTCAA TGCCGAAGAT GAGGCGGAAG GCAGGGCAAG TCTTGACGAC


 


1351
ATCAACGAGA CCTTGCGCCT GATGGTGGAC AGTACGGTTC AGAGTATGGC


 


1401
AAGGGAAAAA TATCTGACTT TGAACGGCGA CCAGATTGAT ACTGCCATTT


 


1451
CTCTGAAAAA CAATCAGTTG AAATTGAACG GTAAAACGTT GCAAAACGAA


 


1501
CCGGAGCCGG ATTTTGATGA AGGCGGTATG GTTTCAGAGC CGCAGCAGTA


 


1551
A






This corresponds to the amino acid sequence <SEQ ID 1840; ORF 590-1>:










m590-1.pep




1
MKKPLISVAA ALLGVALGTP YYLGVKAEES LTQQQKILQE TGFLTVESHQ


 


51
YERGWFTSME TTVIRLKPEL LNNARKYLPD NLKTVLEQPV TLVNHITHGP


 


101
FAGGFGTQAY IETEFKYAPE TEKVLERFFG KQVPASLANT VYFNGSGKME


 


151
VSVPAFDYEE LSGIRLHWEG LTGETVYQKG FKSYRNGYDA PLFKIKLADK


 


201
GDAAFEKVHF DSETSDGINP LALGSSNLTL EKFSLEWKEG VDYNVKLNEL


 


251
VNLVTDLQIG AFINPNGSIA PSKIEVGKLA FSTKTGESGA FINSEGQFRF


 


301
DTLVYGDEKY GPLDIHIAAE HLDASALTVL KRKFAQISAK KMTEEQIRND


 


351
LIAAVKGEAS GLFTNNPVLD IKTFRFTLPS GKIDVGGKIM FKDMKKEDLN


 


401
QLGLMLKKTE ADIRMSIPQK MLEDLAVSQA GNIFSVNAED EAEGRASLDD


 


451
INETLRLMVD STVQSMAREK YLTLNGDQID TAISLKNNQL KLNGKTLQNE


 


501
PEPDFDEGGM VSEPQQ*






m590-1/g590 93.6% identity in 516 aa overlap





a590/m590-1 98.3% identity in 516 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1841>:










g591.seq




1
TTGCAAACCC TTCTAGCTTT TATCTTCGCC ATCCTGATTT TGGTCAGCCT


 


51
GCACGAATTC GGACACTACA TCGTCGCCAG GTTGTGCGGC GTCAAGGTTG


 


101
TGCGTTTTTC CGTCGGCTTC GGCAAACCGT TTTTCACCCG AAAGCGCGGC


 


151
GACACCGAAT GGTGCCTCGC CCCGATTCCG TTGGGCGGCT ACGTCAAAAT


 


201
GGTCGATACG CGCGAAGGCG AAGTATCAGA AGCCGATTTA CCCTACGCTT


 


251
TTGACAAACA ACACCCCGCC AAGCGCATCG CCATCGTCGC CGCCGGTCCG


 


301
CTGACCAACC TCGCActggc ggTTTTGCTG TACGGACTGa gctTttcctt


 


351
cggcgtaaCC GAACTGCGGC CCtatgtcgg cacagtcgaA cccgacaccg


 


401
ttgccgCCCG CACCGGCTTC caaagcggcg acaaAATACa atccgtcaac


 


451
ggcgtTtccg tCCAAGACTG GAGCAGCGCG CAAACCGAAA TCGTcctcAA


 


501
CCTCGAAGCC Ggcaaagtcg ccgtcggcgT TCAGACGGCA TCGGGCGCGC


 


551
AAACCGTCCG CACCAtcgAT GCCGCAGGCA CGCCGGAAGC CGGTAAAATC


 


601
GCAAAAAACC AAGGCTACAT CGGACTGATG CCCTTTAAAA TCACAACCGT


 


651
TGCCGGCGGC GTGGAAAAAG GCAGCCCCGC CGAAAAAGCA GGCCTGAAAC


 


701
CGGGCGACAG GCTGACTGCC GCCGACGGCA AACCCATCGc ctcaTGGCAG


 


751
GAATGggcaa acctgACccg cCAAAGCCCg ggcAAAAAAA Tcaccctgac


 


801
ctacgAaCGC GCcggacaaa cccaTAccgc CGACATCCGC CccgATactg


 


851
TCGAAcagcc cgACCACACC CTGATCgggc gcgTCGGCCT CCGtccgcaG


 


901
CCGGACAGGG CGTGGGACGC GCAAATCCGC CGCAGCTACC GTCCGTCTGT


 


951
TGTCCGCGCA TTCGGCATGG GCTGGGAAAA AACCGTTTCC CACTCGTGGA


 


1001
CAACCCTCAA ATTTTTCGGC AAACTAATCA GCGGCAACGC CTCTGTCAGC


 


1051
CATATTTCCG GGCCGCTGAC CATTGCCGAC ATTGCCGGAC AGTCCGCCGA


 


1101
ACTCGGCTTG CAAAGTTATT TGGAATTTTT AGCGTTGGTC AGCATCAGCC


 


1151
TCGGCGTGCT GAACCTGCTG CCCGTCCCCG TTTTGGACGG CGGGCACCTC


 


1201
GTGTTTTATA CTGTCGAATG GATACGCGGC AAACCTTTGG GCGAACGTGT


 


1251
CCAAAACATC GGTTTGCGCT TCGGGCTCGC CCTGATGATG CTGATGATGG


 


1301
CGGCCGCCTT CTTCAACGAC GTTACCCGGC TGATCGGTTA G






This corresponds to the amino acid sequence <SEQ ID 1842; ORF 591.ng>:










g591.pep..




1
LQTLLAFIFA ILILVSLHEF GHYIVARLCG VKVVRFSVGF GKPFFTRKRG


 


51
DTEWCLAPIP LGGYVKMVDT REGEVSEADL PYAFDKQHPA KRIAIVAAGP


 


101
LTNLALAVLL YGLSFSFGVT ELRPYVGTVE PDTVAARTGF QSGDKIQSVN


 


151
GVSVQDWSSA QTEIVLNLEA GKVAVGVQTA SGAQTVRTID AAGTPEAGKI


 


201
AKNQGYIGLM PFKITTVAGG VEKGSPAEKA GLKPGDRLTA ADGKPIASWQ


 


251
EWANLTRQSP GKKITLTYER AGQTHTADIR PDTVEQPDHT LIGRVGLRPQ


 


301
PDRAWDAQIR RSYRPSVVRA FGMGWEKTVS HSWTTLKFFG KLISGNASVS


 


351
HISGPLTIAD IAGQSAELGL QSYLEFLALV SISLGVLNLL PVPVLDGGHL


 


401
VFYTVEWIRG KPLGERVQNI GLRFGLALMM LMMAAAFFND VTRLIG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1843>:










m591.seq




1
TTGCACACCC TTCTAGCTTT TATCTTCGCC ATCCTGATTT TGGTCAGCCT


 


51
GCACGAGTTC GGACACTACA TCGTTGCCAG ATTGTGCGGC GTCAAAGTCG


 


101
TACGCTTTTC CGTCGGCTTC GGCAAACCGT TTTTCACCCG AAAGCGCGGC


 


151
GACACCGAAT GGTGCCTCGC CCCGATTCCG TTGGGCGGTT ACGTCAAAAT


 


201
GGTCGATACG CGCGAAGGCG AAGTATCAGA AGCCGATTTA CCCTACGCTT


 


251
TTGACAAACA ACACCCCGCC AAGCGCATCG CCATCGTCGC CGCCGGCCCA


 


301
CTGACCAACC TCGCACTGGC GGTTTTGCTG TACGGACTGA GCTTTTCCTT


 


351
CGGCGTAACC GAACTGCGCC CCTACGTCGG CACAGTCGAA CCCGACACCA


 


401
TTGCCGCCCG CGCCGGCTTC CAAAGCGGCG ACAAAATACA ATCCGTCAAC


 


451
GGCACACCCG TTGCAGATTG GGGCAGCGCG CAAACCGAAA TCGTCCTCAA


 


501
CCTCGAAGCC GGCAAAGTCG CCGTCGGCGT TCAGACGGCA TCGGGCGCGC


 


551
AAACCGTCCG CACCATCGAT GCCGCAGGCA CGCCGGAAGC CGGTAAAATC


 


601
GCAAAAAACC AAGGCTACAT CGGACTGATG CCCTTTAAAA TCACAACCGT


 


651
TGCCGGCGGC GTGGAAAAAG GCAGCCCCGC CGAAAAAGCA GGCCTGAAAC


 


701
CGGGCGACAG GCTGACTGCC GCCGACGGCA AACCCATCGC CTCATGGCAA


 


751
GAATGGGCAA ACCTGACCCG CCAAAGCCCC GGCAAAAAAA TCACCCTGAA


 


801
CTACGAACGC GCCGGACAAA CCCATACCGC CGACATCCGC CCCGATACTG


 


851
TCGAACAGTC CGACCACACC CTGATCGGGC GCGTCGGCCT CCGTCCGCAG


 


901
CCGGACAGGG CGTGGGACGC GCAAATCCGC CGCAGCTACC GTCCGTCTGT


 


951
TGTCCGCGCA TTCGGCATGG GCTGGGAAAA AACCGTTTCC CACTCGTGGA


 


1001
CAACCCTCAA ATTTTTCGGC AAACTAATCA GCGGCAACGC CTCCGTCAGC


 


1051
CATATTTCCG GGCCGCTGAC CATTGCCGAC ATTGCCGGAC AGTCCGCCGA


 


1101
ACTCGGCTTG CAAAGTTATT TGGAATTTTT AGCACTGGTC AGCATCAGCC


 


1151
TCGGCGTGCT GAACCTACTG CCCGTCCCTG TTTTGGACGG CGGGCACCTC


 


1201
GTGTTTTATA CTGCCGAATG GATACGCGGC AAACCTTTGG GCGAACGCGT


 


1251
CCAAAACATC GGTTTGCGCT TCGGGCTCGC CCTCATGATG CTGATGATGG


 


1301
CGGTCGCCTT CTTCAACGAC GTTACCCGGC TGCTCGGTTA G






This corresponds to the amino acid sequence <SEQ ID 1844; ORF 591>:










m591.pep..




1
LHTLLAFIFA ILILVSLHEF GHYIVARLCG VKVVRFSVGF GKPFFTRKRG


 


51
DTEWCLAPIP LGGYVKMVDT REGEVSEADL PYAFDKQHPA KRIAIVAAGP


 


101
LTNLALAVLL YGLSFSFGVT ELRPYVGTVE PDTIAARAGF QSGDKIQSVN


 


151
GTPVADWGSA QTEIVLNLEA GKVAVGVQTA SGAQTVRTID AAGTPEAGKI


 


201
AKNQGYIGLM PFKITTVAGG VEKGSPAEKA GLKPGDRLTA ADGKPIASWQ


 


251
EWANLTRQSP GKKITLNYER AGQTHTADIR PDTVEQSDHT LIGRVGLRPQ


 


301
PDRAWDAQIR RSYRPSVVRA FGMGWEKTVS HSWTTLKFFG KLISGNASVS


 


351
HISGPLTIAD IAGQSAELGL QSYLEFLALV SISLGVLNLL PVPVLDGGHL


 


401
VFYTAEWIRG KPLGERVQNI GLRFGLALMM LMMAVAFFND VTRLLG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m591/g591 97.3% identity in 446 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1845>:










a591.seq




1
TTGCACACCC TTCTAGCTTT TATCTTCGCC ATCCTGATTT TGGTCAGCCT


 


51
GCACGAATTC GGACACTACA TCGTCGCCAG ATTGTGCGGC GTCAAGGTTG


 


101
TGCGTTTTTC CGTCGGCTTC GGCAAACCGT TTTTCACCCG AAAGCGCGGC


 


151
GACACCGAAT GGTGCCTCGC CCCGATTCCG TTGGGCGGTT ACGTCAAAAT


 


201
GGTCGACACG CGCGAAGGCG AAGTATCAGA AGCCGATTTA CCCTACGCTT


 


251
TTGACAAACA ACACCCCGCC AAGCGCATCG CCATCGTCGC CGCCGGCCCG


 


301
CTGACCAACC TCGCACTGGC GGTTTTGCTG TACGGACTGA GCTTTTCCTT


 


351
CGGCGTTACC GAACTGCGCC CCTATGTCGG CACAGTCGAA CCCGACACCA


 


401
TTGCCGCCCG CGCCGGCTTC CAAAGCGGCG ACAAAATACA ATCCGTCAAC


 


451
GGCACACCCG TTGCAGATTG GGGCAGCGCG CAAACCGAAA TCGTCCTCAA


 


501
CCTCGAAGCC GGCAAAGTCG CCGTCGGCGT TCAGACGGCA TCGGGCGCGC


 


551
AAACCGTCCG CACCATCGAT GCCGCAGGCA CGCCGGAAGC CGGTAAAATC


 


601
GCAAAAAACC AAGGCTACAT CGGACTGATG CCCTTTAAAA TCACAACCGT


 


651
TGCCGGCGGC GTGGAAAAAG GCAGCCCCGC CGAAAAAGCA GGCCTGAAAC


 


701
CGGGCGACAG GCTGACTGCC GCCGACGGCA AACCCATCGC CTCATGGCAA


 


751
GAATGGGCAA ACCTGACCCG CCAAAGCCCC GGCAAAAAAA TCACCCTGAC


 


801
CTACGAACGC GCCGGACAAA CCCATACCGC CGACATCCGC CCCGATACTG


 


851
TCGAACAGCC CGACCACACC CTGATCGGGC GCGTCGGCCT CCGTCCGCAG


 


901
CCGGACAGGG CGTGGGACGC GCAAATCCGC CGCAGCTACC GTCCGTCTGT


 


951
TGTCCGCGCA TTCGGCATGG GCTGGGAAAA AACCGTTTCC CACTCGTGGA


 


1001
CAACCCTCAA ATTTTTCGGC AAACTAATCA GCGGCAACGC CTCCGTCAGC


 


1051
CATATTTCCG GTCCGCTGAC CATTGCCGAT ATTGCCGGAC AGTCCGCCGA


 


1101
ACTCGGCTTG CAAAGTTATT TGGAATTTTT GGCACTGGTC AGCATCAGCC


 


1151
TCGGCGTGCT GAACCTGCTG CCCGTCCCCG TTTTGGACGG CGGCCACCTC


 


1201
GTGTTTTATA CTGCCGAATG GATACGCGGC AAACCTTTGG GCGAACGCGT


 


1251
CCAAAACATC GGTTTGCGCT TCGGGCTTGC CCTCATGATG CTGATGATGG


 


1301
CGGTCGCCTT CTTCAACGAC GTTACCCGGC TGCTCGGTTA G






This corresponds to the amino acid sequence <SEQ ID 1846; ORF 591.a>:










a591.pep




1
LHTLLAFIFA ILILVSLHEF GHYIVARLCG VKVVRFSVGF GKPFFTRKRG


 


51
DTEWCLAPIP LGGYVKMVDT REGEVSEADL PYAFDKQHPA KRIAIVAAGP


 


101
LTNLALAVLL YGLSFSFGVT ELRPYVGTVE PDTIAARAGF QSGDKIQSVN


 


151
GTPVADWGSA QTEIVLNLEA GKVAVGVQTA SGAQTVRTID AAGTPEAGKI


 


201
AKNQGYIGLM PFKITTVAGG VEKGSPAEKA GLKPGDRLTA ADGKPIASWQ


 


251
EWANLTRQSP GKKITLTYER AGQTHTADIR PDTVEQPDHT LIGRVGLRPQ


 


301
PDRAWDAQIR RSYRPSVVRA FGMGWEKTVS HSWTTLKFFG KLISGNASVS


 


351
HISGPLTIAD IAGQSAELGL QSYLEFLALV SISLGVLNLL PVPVLDGGHL


 


401
VFYTAEWIRG KPLGERVQNI GLRFGLALMM LMMAVAFFND VTRLLG*






m591/a591 99.6% identity in 446 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1847>:










g592.seq..




1
atgattccgg acgtgttcgg tcagattttt tcgggcgcgt tcaaattcga


 


51
cgcggcagca ggcggcttac tcggcggtct gatttcgcaa acgatgatga


 


101
tgggcatcaa acgcggcctg tattccaacg aggcgggtat gggttccgcg


 


151
ccgaacgccg ccgccgccgc cgaagtgaaa caccctgttt cgcaaggtat


 


201
gattcaaatg ctgggcgtgt ttgtcgatac catcatcgtt tgttcttgca


 


251
ccgccttcat catcttgatt taccaacagc cttatggcga tttgagcggt


 


301
gcggcgctga cgcaggcggc gattgtcagc caagtggggc aatggggcgc


 


351
gggtttcctc gccgtcatcc tgtttatgtt tgccttttcc accgttatcg


 


401
gcaactatgc ctatgccgag tccaacgtcc aattcatcaa aagccattgg


 


451
ctgattaccg ccgttttccg tatgctggtt ttggcgtggg tctatttcgg


 


501
cgcggttgcc aatgtgcctt tggtctggga tatggcggat atggcgatgg


 


551
gcatcatggc gtggatcaac ctcgtcgcca tcctgctgct ctcgccattg


 


601
gcgtttatgc tgctgcgcga ttacaccgcc aagctgaaaa tgggcaaaga


 


651
ccccgagttc aaactttccg aacatccggg cctgaaacgc cgcatcaaat


 


701
ccgatgtttg gtaa






This corresponds to the amino acid sequence <SEQ ID 1848; ORF 592.ng>:










g592.pep ..




1
MIPDVFGQIF SGAFKFDAAA GGLLGGLISQ TMMMGIKRGL YSNEAGMGSA


 


51
PNAAAAAEVK HPVSQGMIQM LGVFVDTIIV CSCTAFIILI YQQPYGDLSG


 


101
AALTQAAIVS QVGQWGAGFL AVILFMFAFS TVIGNYAYAE SNVQFIKSHW


 


151
LITAVFRMLV LAWVYFGAVA NVPLVWDMAD MAMGIMAWIN LVAILLLSPL


 


201
AFMLLRDYTA KLKMGKDPEF KLSEHPGLKR RIKSDVW*






The following partial DNA sequence was identified in N. meningitides <SEQ ID 1849>:










m592.seq ..




1
ATGATTCCGG ACGTGTTCGG TCAGATTTTT TCGGGCGCGT TCAAATTCGA


 


51
CGCGGCAGCA GGCGGCTTAC TCGGCGGTCT GATTTCGCAA ACGATGATGA


 


101
TGGGCATCAA ACGCGGCCTG TATTCCAACG AGGCGGGTAT GGGTTCCGCG


 


151
CCGAACGCCG CCGCCGCCGC CGAAGTGAAA CACCCTGTTT CGCAAGGTAT


 


201
GATTCAAATG CTGGGCGTGT TTGTCGATAC CATCATCGTT TGTTCTTGCA


 


251
CCGCCTTCAT CATCTTGATT TACCAACAGC CTTACGGCGA TTTGAGCGGT


 


301
GCGGCGCTGA CGCAGGCGGC GATTGTCAGC CAAGTGGGGC AATGGGGCGC


 


351
GGGCTTCCTC GCCGTCATCC TGTTTATGTT TGCCTTTTCC ACCGTTATCG


 


401
GCAACTATGC CTATGCCGAG TCCAACGTCC AATTCATCAA AAGCCATTGG


 


451
CTGATTACCG CCGTTTTCCG TATGCTGGTT TTGGCGTGGG TCTATTTCGG


 


501
CGCGGTTGCC AATGTGCCTT TGGTCTGGGA TATGGCGGAT ATGGCGATGG


 


551
GCATTATGGC GTGGATCAAC CTTGTCGCCA TCCTGCTGCT CTCGCCCTTG


 


601
GCGTTTATGC TGCTGCGCGA TTACACCGCC AAGCTGAAAA TGGGCAAAGA


 


651
CCCCGAGTTC AAACTTTCCG AACATCCGGG CCTGAAACGC CGTATCAAAT


 


701
CCGACGTTTG GTAA






This corresponds to the amino acid sequence <SEQ ID 1850; ORF 592>:










m592.pep ..




1
MIPDVFGQIF SGAFKFDAAA GGLLGGLISQ TMMMGIKRGL YSNEAGMGSA


 


51
PNAAAAAEVK HPVSQGMIQM LGVFVDTIIV CSCTAFIILI YQQPYGDLSG


 


101
AALTQAAIVS QVGQWGAGFL AVILFMFAFS TVIGNYAYAE SNVQFIKSHW


 


151
LITAVFRMLV LAWVYFGAVA NVPLVWDMAD MAMGIMAWIN LVAILLLSPL


 


201
AFMLLRDYTA KLKMGKDPEF KLSEHPGLKR RIKSDVW*






m592/g592 100.0% identity in 237 aa overlap





The following partial DNA sequence was identified in N. meningitides <SEQ ID 1851>:










a592.seq




1
ATGATTCCGG ACGTGTTCGG TCAGATTTTT TCGGGCGCGT TCAAATTCGA


 


51
CGCGGCAGCA GGCGGCTTAC TCGGCGGTCT GATTTCGCAA ACGATGATGA


 


101
TGGGCATCAA ACGCGGCCTG TATTCCAACG AGGCGGGTAT GGGTTCCGCG


 


151
CCGAACGCCG CCGCCGCCGC CGAAGTGAAA CACCCTGTTT CGCAAGGTAT


 


201
GATTCAAATG CTGGGCGTGT TTGTCGATAC CATCATCGTT TGTTCTTGCA


 


251
CCGCCTTCAT CATCTTGATT TACCAACAGC CTTACGGCGA TTTGAGCGGT


 


301
GCGGCGCTGA CGCAGGCGGC GATTGTCAGC CAAGTGGGGC AATGGGGCGC


 


351
GGGCTTCCTC GCCGTCATCC TGTTTATGTT TGCCTTTTCC ACCGTTATCG


 


401
GCAACTATGC CTATGCCGAG TCCAACGTCC AATTCATCAA AAGCCATTGG


 


451
CTGATTACCG CCGTTTTCCG TATGCTGGTT TTGGCGTGGG TCTATTTCGG


 


501
CGCGGTTGCC AATGTGCCTT TGGTCTGGGA TATGGCGGAT ATGGCGATGG


 


551
GCATTATGGC GTGGATCAAC CTTGTCGCCA TCCTGCTGCT CTCGCCCTTG


 


601
GCGTTTATGC TGCTGCGCGA TTACACCGCC AAGCTGAAAA TGGGCAAAGA


 


651
CCCCGAGTTC AAACTTTCCG AACATCCGGG CCTGAAACGC CGTATCAAAT


 


701
CCGACGTTTG GTAA






This corresponds to the amino acid sequence <SEQ ID 1852; ORF 592.a>:










a592.pep




1
MIPDVFGQIF SGAFKFDAAA GGLLGGLISQ TMMMGIKRGL YSNEAGMGSA


 


51
PNAAAAAEVK HPVSQGMIQM LGVFVDTIIV CSCTAFIILI YQQPYGDLSG


 


101
AALTQAAIVS QVGQWGAGFL AVILFMFAFS TVIGNYAYAE SNVQFIKSHW


 


151
LITAVFRMLV LAWVYFGAVA NVPLVWDMAD MAMGIMAWIN LVAILLLSPL


 


201
AFMLLRDYTA KLKMGKDPEF KLSEHPGLKR RIKSDVW*






m592/a592 100.0% identity in 237 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1853>:










g593.seq..




1
atgcttgaac tgaacggact ctgcaaatgc ttcggcggca aaacggtcgc


 


51
cgacaacatc tgcctgactg tcgggcgcgg caaaatactc gccgtactgg


 


101
ggcggtcggg ctgcggcaaa tccaccctgc tgaatatgat tgcgggcatc


 


151
gtccggccgg acggcggcga aattcggctg aacggggaaa acattacctg


 


201
tatgccgccc gaaaaacgcc gtatctcgct gatgtttcaa gattacgcgc


 


251
tgtttcccca tatgagtgcg ctggaaaata cggcattcgg tttgaaaatg


 


301
caaaaaatgc cgaaagccga agccgaacgc ctcgccttgt cggcacttgc


 


351
cgaagtcggg ctggaaaacg aggcgcaccg caagcctgaa aaactttccg


 


401
gaggcgagaa gcaacggttg gcactggcgc gcgctttggt tgtccgccct


 


451
tccctgctgt tgctggatga atcgttttcc agtttggaca cgcatttgcg


 


501
cgaccggctg cgccgtatga ccgccgaacg catccgcaag ggcggcatcc


 


551
ctgccgtttt ggtaacgcat tcgcccgaag aggcctgcac ggcggcggac


 


601
gaaatcgccg tcatgcacga ggggaaaatc cttcaatgcg gtacgcccga


 


651
aaccttgatt caaacgcctg ccggcgtgca ggtcgcccgt ctgatggggc


 


701
tgcccaatac cgacgatgac cgccatattc cgcaaaatgc cgtgtgcttg


 


751
gacaatcatg gaacggaatg ccgtctgctg tccctcgtcc gcctgcccga


 


801
ctcgctccgg ctttccgccg tccatcccga acacggcgag ctgaccttaa


 


851
acctgactgt cggacaacat acggacggta tttccggaaa cggtacggtc


 


901
cgcatccgcg tcgatgaagg gcgtatcgtc cgtttccgat ga






This corresponds to the amino acid sequence <SEQ ID 1854; ORF 593.ng>:










g593.pep..




1
MLELNGLCKC FGGKTVADNI CLTVGRGKIL AVLGRSGCGK STLLNMIAGI


 


51
VRPDGGEIRL NGENITCMPP EKRRISLMFQ DYALFPHMSA LENTAFGLKM


 


101
QKMPKAEAER LALSALAEVG LENEAHRKPE KLSGGEKQRL ALARALVVRP


 


151
SLLLLDESFS SLDTHLRDRL RRMTAERIRK GGIPAVLVTH SPEEACTAAD


 


201
EIAVMHEGKI LQCGTPETLI QTPAGVQVAR LMGLPNTDDD RHIPQNAVCL


 


251
DNHGTECRLL SLVRLPDSLR LSAVHPEHGE LTLNLTVGQH TDGISGNGTV


 


301
RIRVDEGRIV RFR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1855>:










m593.seq




1
ATGCTTGAAC TGAACGGACT CTGCAAACGC TTCGGCAATA AAACCGTCGC


 


51
CGACAACATC TGCCTGACTG TCGGGCGCGG CAAAATACTC GCCGTTTTGG


 


101
GGCGGTCGGG CTGCGGAAAA TCCACCCTGC TGAATATAAT TGCGGGGATT


 


151
GTCCGGCCGG ACGGCGGGGA AATATGGCTG AACGGAGAAA ACATTACCCG


 


201
TATGCCGCCC GAAAAACGCC GTATCTCGCT GATGTTTCAA GATTACGCGC


 


251
TGTTTCCCCA TATGAGTGCG CTGGAAAATG CGGCATTCGG TTTGAAAATG


 


301
CAAAAAATGC CGAAAGCCGA AGCCGAACGC CTCGCCATGG CGGCACTTGC


 


351
CGAAGTCGGA CTGGAAAACG AGGCGCACCG CAAGCCTGAA AAACTTTCCG


 


401
GAGGCGAGAA GCAACGGCTG GCGTTGGCGC GCGCTTTGGT TGTCCGCCCT


 


451
TCCCTGCTGC TGTTGGACGA ATCGTTTTCC AGTTTGGACA CGCATTTGCG


 


501
CGGCACGCTG CGCCGTATGA CTGCCGAACG TATCCGAAAC GGCGGCATCC


 


551
CTGCCGTTTT GGTAACGCAT TCGCCCGAAG AAGCCTGTAC GACGGCAGAC


 


601
GAAATCGCCG TGATGCATAA AGGGAGGATT CTACAATACG GTACGCCCGA


 


651
AACATTGGTC AAAACACCAT CCTGCGTGCA GGTCGCCCGA CTGATGGGTT


 


701
TGCCCAATAC CGACGATAAC CGCCATATTC CGCAACATGC GGTGCGTTTC


 


751
GACCAAGACG GCATGGAGTG CCGCGTATTA TCCCGTACCT GTTTGCCCGA


 


801
ATCGTTCAGC CTGTCCGTCC TCCATCCGGA ACACGGCATC CTGTGGCTGA


 


851
ACCTCGATAT GCGGCACGCC GGGGCGGTAT CGGGCAAGGA TACGGTACGC


 


901
ATCCATATCG AAGAACGGGA AATCGTCCGC TTCCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1856; ORF 593>:









m593.pep ..










1
MLELNGLCKR FGNKTVADNI CLTVGRGKIL AVLGRSGCGK STLLNIIAGI



 


51
VRPDGGEIWL NGENITRMPP EKRRISLMFQ DYALFPHMSA LENAAFGLKM


 


101
QKMPKAEAER LAMAALAEVG LENEAHRKPE KLSGGEKQRL ALARALVVRP


 


151
SLLLLDESFS SLDTHLRGTL RRMTAERIRN GGIPAVLVTH SPEEACTTAD


 


201
EIAVMHKGRI LQYGTPETLV KTPSCVQVAR LMGLPNTDDN RHIPQHAVRF


 


251
DQDGMECRVL SRTCLPESFS LSVLHPEHGI LWLNLDMRHA GAVSGKDTVR


 


301
IHIEEREIVR FR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m593/g593 83.4% identity in 313 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1857>:










a593.seq




1
ATGCTTGAAC TGAACGGACT CTGCAAACGC TTCGGCGGCA AAACGGTTGC


 


51
CGACGATATC TGCCTGACTG TCGGGCGCGG CAAAATACTC GCCGTTTTGG


 


101
GGCGGTCGGG CTGCGGCAAA TCCACCCTGC TGAATATGAT TGCGGGCATC


 


151
GTCCGGCCGG ACGGCGGGGA AATATGGCTG AATGGGGAAA ACATTACCCG


 


201
TATGCCGCCC GAAAAACGCC GTATTTCGCT GATGTTTCAA GATTACGCGC


 


251
TGTTTCCCCA TATGAGTGCA CTGGAAAATG CGGCATTCGG TTTGAAAATG


 


301
CAAAAAATGC CGAAAGCCGA AGCCGAAAGC CTCGCCATGG CGGCACTTGC


 


351
CGAAGTCGGA CTGGAAAACG AGGCGCACCG CAAGCCTGAN AAACTTTCCG


 


401
GAGGCGAAAA GCAACGGTTG GCACTGGCGC GCGCTTTGGT TGTCCGCCCT


 


451
TCCCTGCTGC TGTTGGACGA ATCGTTTTCC AGTTTGGACA CGCATTTGCG


 


501
CGACCGGCTG CGCCGCATGA CTGCCGAACG TATCCGCAAG GGCGGCATCC


 


551
CTGCCGTTTT GGTAACGCAT TCGCCCGAAG AGGCCTGCAC GGCGGCAGAC


 


601
GAAATCGCCG TCATGCACGA GGGGAAAATC CTTCAATGCG GTACGCCCGA


 


651
AACCTTGGTT CAAACGCCTG CCGGCGTGCA GGTCGCCCAT CTGATGGGGC


 


701
TGCCCAATAC CGACGATGAC CGCCATATTC CGCAACATGC GGTGCGTTTC


 


751
GACCAAGACG GCATGGAGTG CCGCGTATTA TCCCGTACCT GTTTGCCCGA


 


801
ATCGTTCAGC CTGTCCGTCC TCCATCCGGA ACACGGCATC CTGTGGCTGA


 


851
ACCTCGATAT GCCGCACGCC GGTGAAATAT CGGGAAACGA TACGGTACGC


 


901
ATCCATATCG AAGACAGGGA AATCGTCCGC TTCCGCTGA






This corresponds to the amino acid sequence <SEQ ID 1858; ORF 593.a>:










a593.pep




1
MLELNGLCKR FGGKTVADDI CLTVGRGKIL AVLGRSGCGK STLLNMIAGI


 


51
VRPDGGEIWL NGENITRMPP EKRRISLMFQ DYALFPHMSA LENAAFGLKM


 


101
QKMPKAEAES LAMAALAEVG LENEAHRKPX KLSGGEKQRL ALARALVVRP


 


151
SLLLLDESFS SLDTHLRDRL RRMTAERIRK GGIPAVLVTH SPEEACTAAD


 


201
EIAVMHEGKI LQCGTPETLV QTPAGVQVAH LMGLPNTDDD RHIPQHAVRF


 


251
DQDGMECRVL SRTCLPESFS LSVLHPEHGI LWLNLDMPHA GEISGNDTVR


 


301
IHIEDREIVR FR*






m593/a593 92.9% identity in 312 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1859>:










g594.seq..




1
atgggtgcag ataccgatgg cgacaaggat gttcggctta atcgaacggg


 


51
tctcgttttt agcatactcc ggctgctgtt ccgcatcgga attgggatcg


 


101
gtaagttcgc cgttcaggcc tttcaggtct ttaagctgct gatctgtacg


 


151
gttgagcacc caaatcggtt tgccttgcca ctcggcggtc agcagctgac


 


201
ccgcttcgat tttactgaca tccacctcga cggcagcacc ggaggccttg


 


251
gctttttccg aagggaaaaa actggccaca aacggcgttg ccacacccaa


 


301
tgctgccact ccgcccgcgc cgcaggtcgc aagtgtcagg aaacggcggc


 


351
ggccgttgtt gatttcttga ttatccatta ttcagtcgtc ctaatatttt


 


401
gggaatgccg agccattaaa cattgcaatt ttacccagtt tgcagtgata


 


451
ctcaaagcat tatttaaaat aaggtaa






This corresponds to the amino acid sequence <SEQ ID 1860; ORF 594.ng>:










g594.pep




1
MGADTDGDKD VRLNRTGLVF SILRLLFRIG IGIGKFAVQA FQVFKLLICT


 


51
VEHPNRFALP LGGQQLTRFD FTDIHLDGST GGLGFFRREK TGHKRRCHTQ


 


101
CCHSARAAGR KCQETAAAVV DFLIIHYSVV LIFWECRAIK HCNFTQFAVI


 


151
LKALFKIR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1861>:










m594.seq




1
ATGGGTGCAG ATACCGATGG CGACAAGGAT GTTCGGCTTA ATCGAACGGG


 


51
TCTCGTTTTT AGCATACTCC GGCTGCTGTT CCGCATCGGA ATTGGGATCG


 


101
GTAAGTTCGC CGTTCAGGCC TTTCAGGTCT TTAAGCTGCT GATCTGTACG


 


151
GTTGAGCACC CAAATCGGTT TGCCTTGCCA CTCGGCGGTC AGCAGCTGAC


 


201
CCGCTTCGAT TTTACTGACA TCCACCTCGA CGGCAGCACC GGCGGCCTTG


 


251
GCTTTTTCCG AAGGGAAAAA ACTGGCCACA AACGGCGTTG CCACACCCAA


 


301
TGCTGCCACT CCGCCCGCGC CGCAGGTCGC GAGTGTCAGG AAACGGCGGC


 


351
GGCCGTTGTT GATTTCTTGA TTATCCATTA TTCAGTCGTC CTAATATTTT


 


401
GGGAATACCG AGCCATTAAA CGTTGCAATT TTACCCAGTT TGCAGTGATA


 


451
CTCAAAGCAT TATTTAAAAT AAGGTAA






This corresponds to the amino acid sequence <SEQ ID 1862; ORF 594>:










m594.pep




1
MGADTDGDKD VRLNRTGLVF SILRLLFRIG IGIGKFAVQA FQVFKLLICT


 


51
VEHPNRFALP LGGQQLTRFD FTDIHLDGST GGLGFFRREK TGHKRRCHTQ


 


101
CCHSARAAGR ECQETAAAVV DFLIIHYSVV LIFWEYRAIK RCNFTQFAVI


 


151
LKALFKIR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m594/g594 98.1% identity in 158 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1863>:










a594.seq




1
ATGGGTGCAG ATACCGATGG CGACAAGGAT GTTCGGCTTA ATCGAACGGG


 


51
TCTCGTTTTT AGCATACTCC GGCTGCTGTT CCGCATCGGA ATTGGGATCG


 


101
GTAAGTTCGC CGTTCAGGCC TTTCAGGTCT TTAAGCTGCT GATCTGTACG


 


151
GTTGAGCACC CAAATCGGTT TGCCTTGCCA CTCGGCGGTC AGCAACTGAC


 


201
CCGCTTCGAT TTTACTGACA TCCACCTCGA CGGCAGCACC GGCGGCCTTG


 


251
GCTTTTTCCG AAGGGAAAAA ACTGGCCACA AACGGCGTTG CCACACCCAA


 


301
TGCTGCCACT CCGCCCGCGC CGCAGGTCGC GAGTGTCAGG AAACGGCGGC


 


351
GGCCGTTGTT GATTTCTTGA TTATCCATTA TTCAGTCGTC CTAATATTTT


 


401
GGGAATACCG AGCCATTAAA CGTTGCAATT TTACCCAGTT TGCAGTGATA


 


451
CTCAAAGCAT TATTTAAAAT AAGGTAA






This corresponds to the amino acid sequence <SEQ ID 1864; ORF 594.a>:










a594.pep




1
MGADTDGDKD VRLNRTGLVF SILRLLFRIG IGIGKFAVQA FQVFKLLICT


 


51
VEHPNRFALP LGGQQLTRFD FTDIHLDGST GGLGFFRREK TGHKRRCHTQ


 


101
CCHSARAAGR ECQETAAAVV DFLIIHYSVV LIFWEYRAIK RCNFTQFAVI


 


151
LKALFKIR*






m594/a594 100.0% identity in 158 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1865>:










g595.seq..




1
atgagaaaat tcaatttgac cgcattgtcc gtgatgcttg ccttgggttt


 


51
gaccgcgtgc cagccgccgg aggcggagaa agccgcgccg gccgcgtccg


 


101
gtgagaccca atccgccaac gaaggcggtt cggtcggtat cgccgtcaac


 


151
gacaatgcct gcgaaccgat gaatctgacc gtgccgagcg gacaggttgt


 


201
gttcaatatt aaaaacaaca gcggccgcaa gctcgaatgg gaaatcctga


 


251
agggcgtgat ggtggtggac gaacgcgaaa atatcgcccc ggggctttcc


 


301
gacaaaatga accgtaacct gctgccgggc gaatacgaaa tgacctgcgg


 


351
ccttttgacc aatccgcgcg gcaagctggt ggtagccgac agcggcttta


 


401
aagacaccgc caacgaagcg gatttggaaa aactgcccca accgctcgcc


 


451
gactataaag cctacgttca aggcgaggtt aaagagctgg cggcgaaaac


 


501
caaaaccttt accgaagccg tcaaagcagg cgacattgaa aaggcgaaat


 


551
ccctgtttgc cgccacccgc gtccattacg aacgcatcga accgattgcc


 


601
gagcttttca gcgaactcga ccccgtcatc gatgcgtgtg aagacgactt


 


651
caaagacggt gcgaaagatg ccgggtttac cggcttccac cgtatcgaac


 


701
acgccctttg ggtggaaaaa gacgtatccg gcgtgaagga aaccgcggcc


 


751
aaactgatga ccgatgtcga agccctgcaa aaagaaatcg acgcattggc


 


801
gttccctccg ggcaaagtgg tcggcggcgc gtccgaactg attgaagaag


 


851
cggcgggcag taaaatcagc ggcgaagaag accgttacag ccacaccgat


 


901
ttgagcgact tccaagctaa tgcggacgga tctaaaaaaa tcgtcgattt


 


951
gttccgtccg ttgattgagg ccaaaaacaa agccttgttg gaaaaaaccg


 


1001
ataccaactt caaacaggtc aacgaaattc tggcgaaata ccgcaccaaa


 


1051
gacggttttg aaacctacga caagctgagc gaagccgacc gcaaagcatt


 


1101
acaggctcct attaacgcgc ttgccgaaga ccttgcccaa cttcgcggca


 


1151
tactcggctt gaaataa






This corresponds to the amino acid sequence <SEQ ID 1866; ORF 595.ng>:









g595.pep ..










1
MRKFNLTALS VMLALGLTAC QPPEAEKAAP AASGETQSAN EGGSVGIAVN



 


51
DNACEPMNLT VPSGQVVFNI KNNSGRKLEW EILKGVMVVD ERENIAPGLS


 


101
DKMNRNLLPG EYEMTCGLLT NPRGKLVVAD SGFKDTANEA DLEKLPQPLA


 


151
DYKAYVQGEV KELAAKTKTF TEAVKAGDIE KAKSLFAATR VHYERIEPIA


 


201
ELFSELDPVI DACEDDFKDG AKDAGFTGFH RIEHALWVEK DVSGVKETAA


 


251
KLMTDVEALQ KEIDALAFPP GKVVGGASEL IEEAAGSKIS GEEDRYSHTD


 


301
LSDFQANADG SKKIVDLFRP LIEAKNKALL EKTDTNFKQV NEILAKYRTK


 


351
DGFETYDKLS EADRKALQAP INALAEDLAQ LRGILGLK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1867>:










m595.seq




1
ATGAGAAAAT TCAATTTGAC CGCATTGTCC GTGATGCTTG CCTTAGGTTT


 


51
GACCGCGTGC CAGCCGCCGG AGGCGGAGAA AGCTGCGCCG GCAGCGTCCG


 


101
GTGAGGCGCA AACCGCCAAC GAGGGCGGTT CGGTCAGTAT CGCCGTCAAC


 


151
GACAATGCCT GCGAACCGAT GGAACTGACC GTGCCGAGCG GACAGGTTGT


 


201
GTTCAATATT AAAAACAACA GCGGCCGCAA GCTCGAATGG GAAATCCTGA


 


251
AAGGCGTGAT GGTGGTGGAC GAGCGCGAAA ACATCGCCCC CGGACTTTCC


 


301
GATAAAATGA CCGTCACCCT GTTGCCGGGC GAATACGAAA TGACTTGCGG


 


351
TCTTTTGACC AATCCGCGCG GCAAGCTGGT GGTAACCGAC AGCGGCTTTA


 


401
AAGACACCGC CAACGAAGCG GATTTGGAAA AACTGTCCCA ACCGCTCGCC


 


451
GACTATAAAG CCTACGTTCA AGGCGAGGTT AAAGAGCTGG TGGCGAAAAC


 


501
CAAAACTTTT ACCGAAGCCG TCAAAGCAGG CGACATTGAA AAGGCGAAAT


 


551
CCCTGTTTGC CGACACCCGC GTCCATTACG AACGCATCGA ACCGATTGCC


 


601
GAGCTTTTCA GCGAACTCGA CCCCGTCATC GATGCGCGTG AAGACGACTT


 


651
CAAAGACGGC GCGAAAGATG CCGGATTTAC CGGCTTTCAC CGTATCGAAT


 


701
ACGCCCTTTG GGTGGAAAAA GACGTGTCCG GCGTGAAGGA AATTGCAGCG


 


751
AAACTGATGA CCGATGTCGA AGCCCTGCAA AAAGAAATCG ACGCATTGGC


 


801
GTTTCCTCCG GGCAAGGTGG TCGGCGGCGC GTCCGAACTG ATTGAAGAAG


 


851
TGGCGGGCAG TAAAATCAGC GGCGAAGAAG ACCGGTACAG CCACACCGAT


 


901
TTGAGCGACT TCCAAGCCAA TGTGGACGGA TCTAAAAAAA TCGTCGATTT


 


951
GTTCCGTCCG CTGATCGAGG CCAAAAACAA AGCCTTGTTG GAAAAAACCG


 


1001
ATACCAACTT CAAACAGGTC AACGAAATTC TGGCGAAATA CCGGACTAAA


 


1051
GACGGTTTTG AAACCTACGA CAAGCTGGGC GAAGCCGACC GCAAAGCGTT


 


1101
ACAGGCCTCT ATTAACGCGC TTGCCGAAGA CCTTGCCCAA CTTCGCGGCA


 


1151
TACTCGGCTT GAAATAA






This corresponds to the amino acid sequence <SEQ ID 1868; ORF 595>:










m595.pep




1
MRKFNLTALS VMLALGLTAC QPPEAEKAAP AASGEAQTAN EGGSVSIAVN


 


51
DNACEPMELT VPSGQVVFNI KNNSGRKLEW EILKGVMVVD ERENIAPGLS


 


101
DKMTVTLLPG EYEMTCGLLT NPRGKLVVTD SGFKDTANEA DLEKLSQPLA


 


151
DYKAYVQGEV KELVAKTKTF TEAVKAGDIE KAKSLFADTR VHYERIEPIA


 


201
ELFSELDPVI DAREDDFKDG AKDAGFTGFH RIEYALWVEK DVSGVKEIAA


 


251
KLMTDVEALQ KEIDALAFPP GKVVGGASEL IEEVAGSKIS GEEDRYSHTD


 


301
LSDFQANVDG SKKIVDLFRP LIEAKNKALL EKTDTNFKQV NEILAKYRTK


 


351
DGFETYDKLG EADRKALQAS INALAEDLAQ LRGILGLK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m595/g595 95.4% identity in 388 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1869>:










a595.seq




1
ATGAGAAAAT TCAATTTGAC CGCATTGTCC GTGATGCTTG CCTTAGGTTT


 


51
GACCGCGTGC CAGCCGCCGG AGGCGGAGAA AGCTGCGCCG GCAGCGTCCG


 


101
GTGAGGCGCA AACCGCCAAC GAGGGCGGTT CGGTCAGTAT CGCCGTCAAC


 


151
GACAATGCCT GCGAACCGAT GGAACTGACC GTGCCGAGCG GACAGGTTGT


 


201
GTTCAATATT AAAAACAACA GCGGCCGCAA GCTCGAATGG GAAATCCTGA


 


251
AAGGCGTGAT GGTGGTGGAC GAGCGCGAAA ACATCGCCCC CGGACTTTCC


 


301
GATAAAATGA CCGTCACCCT GTTGCCGGGC GAATACGAAA TGACTTGCGG


 


351
TCTTTTGACC AATCCGCGCG GCAAGCTGGT GGTAACCGAC AGCGGCTTTA


 


401
AAGACACCGC CAACGAAGCG GATTTGGAAA AACTGTCCCA ACCGCTCGCC


 


451
GACTATAAAG CCTATGTTCA AGGCGAAGTC AAAGAGCTGG TGGCGAAAAC


 


501
CAAAACCTTT ACCGAAGCCG TCAAAGCAGG CGACATTGAA AAGGCGAAAT


 


551
CCCTGTTTGC CGACACCCGC GTCCATTACG AACGCATCGA ACCGATTGCC


 


601
GAGCTTTTCA GCGAACTCGA CCCCGTCATC GATGCGCGTG AAGACGACTT


 


651
CAAAGACGGC GCGAAAGATG CCGGATTTAC CGGCTTCCAC CGTATCGAAT


 


701
ACGCCCTTTG GGTGGAAAAA GACGTGTCCG GCGTGAAGGA AATTGCAGCG


 


751
AAACTGATGA CCGATGTCGA AGCCCTGCAA AAAGAAATCG ACGCATTGGC


 


801
GTTTCCTCCG GGCAAGGTGG TCGGCGGCGC GTCCGAACTG ATTGAAGAAG


 


851
TGGCGGGCAG TAAAATCAGC GGCGAAGAAG ACCGGTACAG CCACACCGAT


 


901
TTGAGCGACT TCCAAGCCAA TGTGGACGGA TCGAAAAAAA TCGTCGATTT


 


951
GTTCCGTCCG TTGATCGAGA CCAAAAACAA AGCCTTGTTG GAAAAAACCG


 


1001
ATACCAACTT CAAACAGGTC AACGAAATTC TGGCGAAATA CCGGACTAAA


 


1051
GACGGTTTTG AAACCTACGA CAAGCTGGGC GAAGCCGACC GCAAAGCGTT


 


1101
ACAGGCCTCT ATTAACGCGC TTGCCGAAGA CCTTGCCCAA CTTCGCGGCA


 


1151
TACTCGGCTT GAAATAA






This corresponds to the amino acid sequence <SEQ ID 1870; ORF 595.a>:










a595.pep




1
MRKFNLTALS VMLALGLTAC QPPEAEKAAP AASGEAQTAN EGGSVSIAVN


 


51
DNACEPMELT VPSGQVVFNI KNNSGRKLEW EILKGVMVVD ERENIAPGLS


 


101
DKMTVTLLPG EYEMTCGLLT NPRGKLVVTD SGFKDTANEA DLEKLSQPLA


 


151
DYKAYVQGEV KELVAKTKTF TEAVKAGDIE KAKSLFADTR VHYERIEPIA


 


201
ELFSELDPVI DAREDDFKDG AKDAGFTGFH RIEYALWVEK DVSGVKEIAA


 


251
KLMTDVEALQ KEIDALAFPP GKVVGGASEL IEEVAGSKIS GEEDRYSHTD


 


301
LSDFQANVDG SKKIVDLFRP LIETKNKALL EKTDTNFKQV NEILAKYRTK


 


351
DGFETYDKLG EADRKALQAS INALAEDLAQ LRGILGLK*






m595/a595 99.7% identity in 388 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1871>:









g596.seq. (partial).










1
..atgctgctct tggacgagcc gaccaaccac ttggatgcgg aatcggtgga



 


51
  atggctggag caattcctcg tgcgcttccc cggcacagtg gtcgcggtaa


 


101
  cgcacgaccg ctacttcctc gacaacgccg ccgaatggat tttggaactc


 


151
  gaccgcggac acggcattcc gtggaaaggc aattactcgt cttggctgga


 


201
  gcagaaagaa aaacgcttgg aaaacgaggc gaaatccgaa gccgcgcgcg


 


251
  tgaaggcgat gaagcaggaa ttggaatggg tgcgccaaaa tgccaaaggc


 


301
  cgccaagcca agcccaaagc gcgtttggcg cgttttgaag aaatgagcaa


 


351
  ctacgaatac caaaaacgca acgaaactca ggaaatcttt atccctgttg


 


401
  ccgagcgttt gggtaacgaa gtgattgaat ttgtgaatgt ttccaaatcg


 


451
  ttcggcgata aagtgctgat tgacggtttg agcttcaaag tgccggcggg


 


501
  cgcgattgtc ggcatcatcg gcccgaacgg cgcgggtaaa tcgacgctgt


 


551
  tcaaaatgat tgcgggcaaa gagcagcccg attcgggcga agtgaaaatc


 


601
  gggcaaaccg tgaaaatgag cttgattgac caaagccgcg aaggtttgca


 


651
  aaacgacaaa accgtgttcg acaacattgc cgaaggtcgc gatattttgc


 


701
  aggtcggaca gtttgaaatc cccgcccgcc aatatttggg acgcttcaac


 


751
  tttaaaggca gcgaccaaag caaaatcgca aggcagcttt ccggcggcga


 


801
  acgcggccgt ctgcacttgg caaaaacctt gttgggcggc ggcaatgtgt


 


851
  tgctgctgga cgaaccgtcc aacgatctcg acgtggaaac cctgcgcgcg


 


901
  ttggaagacg cattgttgga atttgccggc agcgtgatgg tgatttcgca


 


951
  cgaccgctgg tttctcgacc gcatagccac gcatatcttg gcgtgtgaag


 


1001
  gcgactccaa atgggtgttc ttcgacggca actatcaaga atacgaagcc


 


1051
  gacaagaaac gccgactcgg caaagaaggc gcgaaaccga aacgcatcaa


 


1101
  atacaaaccg gtaacgcgtt aa






This corresponds to the amino acid sequence <SEQ ID 1872; ORF 596.ng>:









g596.pep (partial).










1
..MLLLDEPTNH LDAESVEWLE QFLVRFPGTV VAVTHDRYFL DNAAEWILEL



 


51
  DRGHGIPWKG NYSSWLEQKE KRLENEAKSE AARVKAMKQE LEWVRQNAKG


 


101
  RQAKPKARLA RFEEMSNYEY QKRNETQEIF IPVAERLGNE VIEFVNVSKS


 


151
  FGDKVLIDGL SFKVPAGAIV GIIGPNGAGK STLFKMIAGK EQPDSGEVKI


 


201
  GQTVKMSLID QSREGLQNDK TVFDNIAEGR DILQVGQFEI PARQYLGRFN


 


251
  FKGSDQSKIA RQLSGGERGR LHLAKTLLGG GNVLLLDEPS NDLDVETLRA


 


301
  LEDALLEFAG SVMVISHDRW FLDRIATHIL ACEGDSKWVF FDGNYQEYEA


 


351
  DKKRRLGKEG AKPKRIKYKP VTR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1873>:










m596.seq..




1
ATGTCCCAAC AATACGTCTA TTCTATGCTG CGCGTGAGCA AGGTTGTGCC


 


51
GCCGCAGAAA ACCATCATTA AAGATATTTC CCTTTCTTTC TTCCCCGGCG


 


101
CGAAAATCGG CCTGCTCGGT TTGAACGGCG CGGGCAAGTC CACCGTGCTG


 


151
CGGATTATGG CGGGCGTGGA TAAGGAATTT GAGGGCGAAG CCGTGCCGAT


 


201
GGGCGGCATC AAAATCGGCT ACCTGCCGCA AGAGCCTGAG CTTGATCCGG


 


251
AAAAAACCGT GCGCGAGGAA GTGGAAAGCG GTTTGGGCGA AGTGGCTGCC


 


301
GCGCAGAAAC GTTTGGAAGA AGTGTATGCC GAGTACGCCA ATCCTGATGC


 


351
GGATTTTGAC GCGTTGGCAG AAGAGCAGGG CCGCTTGGAA GCGATTATTG


 


401
CGGCAGGTTC GTCCACGGGC GGCGGTGCGG AACACGAATT GGAAATCGCC


 


451
GCCGACGCGC TGCGCCTGCC GGAATGGGAT GCCAAAATCG ATAATTTGTC


 


501
CGGCGGTGAA AAACGCCGCG TTGCCTTGTG CAAACTCTTG TTGAGCAAGC


 


551
CCGATATGCT TTTGCTGGAC GAGCCGACCA ACCACTTGGA TGCGGAATCG


 


601
GTCGAGTGGC TGGAGCAATT TCTCGTGCGC TTCCCCGGCA CAGTCGTTGC


 


651
GGTAACGCAC GACCGCTACT TCCTCGACAA CGCCGCCGAA TGGATTTTGG


 


701
AACTCGACCG CGGCCATGGT ATTCCGTGGA AAGGCAATTA CTCGTCTTGG


 


751
CTGGAGCAGA AAGAAAAACG CTTGGAAAAC GAGGCAAAAT CCGAAGCCGC


 


801
GCGCGTGAAG GCGATGAAGC AGGAATTGGA ATGGGTGCGC CAAAATGCCA


 


851
AAGGCCGCCA AGCCAAGTCC AAAGCGCGTT TGGCTCGTTT TGAAGAAATG


 


901
AGCAACTACG AATACCAAAA ACGCAATGAA ACGCAGGAAA TCTTTATTCC


 


951
CGTTGCCGAG CGTTTGGGTA ACGAAGTGAT TGAATTTGTA AATGTTTCCA


 


1001
AATCGTTCGG CGATAAAGTG CTGATTGACG ATTTGAGCTT CAAAGTGCCT


 


1051
GCGGGCGCGA TTGTCGGCAT CATCGGCCCG AACGGCGCGG GTAAATCTAC


 


1101
GCTGTTCAAA ATGATTTCGG GCAAAGAGCA GCCTGATTCC GGCGAGGTGA


 


1151
AAATCGGACA AACCGTGAAA ATGAGCTTGA TTGACCAAAG CCGCGAAGGT


 


1201
TTGCAAAACG ACAAAACCGT GTTCGACAAC ATTGCCGAAG GCCGCGACAT


 


1251
TTTGCAGGTT GGTCAGTTTG AAATTCCCGC CCGCCAATAT TTGGGGCGTT


 


1301
TCAACTTCAA AGGCAGCGAC CAAAGCAAAA TTGCAGGTCA ATTGTCTGGC


 


1351
GGCGAACGCG GTCGTCTGCA CTTGGCAAAA ACCTTGTTGA GCGGCGGCAA


 


1401
TGTATTGCTG CTGGATGAAC CGTCTAACGA CCTTGACGTG GAAACCCTGC


 


1451
GCGCGTTGGA AGACGCATTG TTGGAATTTG CCGGCAGCGT GATGGTGATT


 


1501
TCGCACGACC GTTGGTTCCT CGACCGCATC GCCACGCATA TCTTGGCGTG


 


1551
TGAAGGCGAC TCTAAATGGG TGTTCTTCGA CGGCAACTAT CAGGAATACG


 


1601
AAGCCGACAA GAAACGCCGT TTGGGCGAAG AAGGCGCGAA ACCGAAACGC


 


1651
ATCAAATACA AACCGGTAAC GCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1874; ORF 596>:










m596.pep..




1
MSQQYVYSML RVSKVVPPQK TIIKDISLSF FPGAKIGLLG LNGAGKSTVL


 


51
RIMAGVDKEF EGEAVPMGGI KIGYLPQEPE LDPEKTVREE VESGLGEVAA


 


101
AQKRLEEVYA EYANPDADFD ALAEEQGRLE AIIAAGSSTG GGAEHELEIA


 


151
ADALRLPEWD AKIDNLSGGE KRRVALCKLL LSKPDMLLLD EPTNHLDAES


 


201
VEWLEQFLVR FPGTVVAVTH DRYFLDNAAE WILELDRGHG IPWKGNYSSW


 


251
LEQKEKRLEN EAKSEAARVK AMKQELEWVR QNAKGRQAKS KARLARFEEM


 


301
SNYEYQKRNE TQEIFIPVAE RLGNEVIEFV NVSKSFGDKV LIDDLSFKVP


 


351
AGAIVGIIGP NGAGKSTLFK MISGKEQPDS GEVKIGQTVK MSLIDQSREG


 


401
LQNDKTVFDN IAEGRDILQV GQFEIPARQY LGRFNFKGSD QSKIAGQLSG


 


451
GERGRLHLAK TLLSGGNVLL LDEPSNDLDV ETLRALEDAL LEFAGSVMVI


 


501
SHDRWFLDRI ATHILACEGD SKWVFFDGNY QEYEADKKRR LGEEGAKPKR


 


551
IKYKPVTR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m596 g596 98.4% identity in 373 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1875>:










a596.seq




1
ATGTCCCAAC AATACGTCTA TTCTATGCTG CGCGTGAGCA AGGTTGTGCC


 


51
GCCGCAGAAA ACCATCATTA AAGATATTTC CCTTTCTTTC TTCCCCGGCG


 


101
CGAAAATCGG TTTGCTCGGT TTGAACGGCG CGGGCAAGTC CACCGTGCTG


 


151
CGGATTATGG CGGGCGTGGA TAAAGAATTT GAGGGCGAAG CCGTGCCGAT


 


201
GGGCGGTATT AAAATCGGCT ACCTGCCGCA AGAGCCTGAG CTTGATCCGG


 


251
AAAAAACCGT GCGTGAGGAA GTGGAAAGCG GTTTGGGCGA AGTGGCTGCC


 


301
GCGCAGAAAC GTTTGGAGGA AGTGTATGCC GAGTACGCCA ATCCCGATGC


 


351
GGATTTTGAC GCGTTGGCGG AAGAGCAGGG GCGTTTGGAA GCGATTATTG


 


401
CGGCGGGTTC GTCCACGGGC GGCGGTGCGG AACACGAATT GGAAATCGCT


 


451
GCCGACGCGC TGCGCCTGCC GGAATGGGAT GCCAAAATCG ATAATTTGTC


 


501
CGGCGGTGAA AAACGCCGCG TCGCTTTGTG CAAACTCTTG TTGAGCAAGC


 


551
CCGATATGCT TTTGCTGGAC GAGCCGACCA ACCACTTGGA TGCGGAATCG


 


601
GTCGAGTGGC TGGAGCAATT TCTCGTGCGC TTCCCCGGTA CAGTCGTTGC


 


651
CGTAACACAC GACCGCTACT TCCTCGACAA CGCCGCCGAA TGGATTTTGG


 


701
AACTCGACCG CGGGCACGGT ATTCCGTGGA AAGGAAATTA CTCGTCTTGG


 


751
TTGGAGCAGA AAGAAAAACG TTTGGAAAAC GAGGCGAAAT CCGAAGCCGC


 


801
GCGCGTGAAA GCGATGAAGC AGGAATTGGA ATGGGTGCGC CAAAATGCCA


 


851
AAGGCCGTCA AGCCAAGTCC AAAGCGCGTT TGGCGCGTTT TGAAGAAATG


 


901
AGCAACTATG AATACCAAAA ACGCAATGAA ACGCAGGAAA TCTTCATTCC


 


951
CGTCGCCGAG CGTTTGGGTA ACGAAGTGAT TGAATTTGTG AATGTTTCCA


 


1001
AATCGTTCGG CGACAAAGTG CTGATTGACG ATTTGAGCTT CAAAGTGCCT


 


1051
GCGGGCGCGA TTGTCGGCAT CATCGGTCCG AACGGCGCGG GTAAATCGAC


 


1101
ACTGTTTAAA ATGATTGCGG GCAAAGAGCA GCCCGATTCC GGTGAAGTGA


 


1151
AAATCGGGCA AACCGTGAAA ATGAGCTTGA TTGACCAAAG CCGCGAAGGT


 


1201
TTGCAAAACG ACAAAACCGT GTTCGACAAC ATTGCCGAAG GTCGCGATAT


 


1251
TTTACAGGTC GGGCAGTTTG AAATCCCCGC CCGCCAATAT TTGGGACGCT


 


1301
TCAATTTCAA AGGCAGCGAC CAAAGCAAAA TCACGGGGCA GCTTTCCGGC


 


1351
GGCGAACGCG GACGTTTGCA CTTGGCAAAA ACCTTGTTGG GCGGTGGCAA


 


1401
TGTGTTGCTG CTGGACGAAC CGTCCAACGA CCTCGACGTG GAAACCCTGC


 


1451
GCGCGTTGGA AGACGCATTG CTGGAATTTG CCGGCAGCGT GATGGTGATT


 


1501
TCGCACGACC GCTGGTTCCT CGACCGTATT GCTACGCATA TCTTGGCTTG


 


1551
CGAAGGCGAC TCCAAATGGG TGTTCTTTGA CGGCAACTAT CAGGAATACG


 


1601
AAGCCGACAA GAAACGCCGA CTCGGCGAAG AAGGCACGAA ACCGAAACGC


 


1651
ATCAAATACA AACCGGTAAC GCGTTAA






This corresponds to the amino acid sequence <SEQ ID 1876; ORF 596.a>:










a596.pep




1
MSQQYVYSML RVSKVVPPQK TIIKDISLSF FPGAKIGLLG LNGAGKSTVL


 


51
RIMAGVDKEF EGEAVPMGGI KIGYLPQEPE LDPEKTVREE VESGLGEVAA


 


101
AQKRLEEVYA EYANPDADFD ALAEEQGRLE AIIAAGSSTG GGAEHELEIA


 


151
ADALRLPEWD AKIDNLSGGE KRRVALCKLL LSKPDMLLLD EPTNHLDAES


 


201
VEWLEQFLVR FPGTVVAVTH DRYFLDNAAE WILELDRGHG IPWKGNYSSW


 


251
LEQKEKRLEN EAKSEAARVK AMKQELEWVR QNAKGRQAKS KARLARFEEM


 


301
SNYEYQKRNE TQEIFIPVAE RLGNEVIEFV NVSKSFGDKV LIDDLSFKVP


 


351
AGAIVGIIGP NGAGKSTLFK MIAGKEQPDS GEVKIGQTVK MSLIDQSREG


 


401
LQNDKTVFDN IAEGRDILQV GQFEIPARQY LGRFNFKGSD QSKITGQLSG


 


451
GERGRLHLAK TLLGGGNVLL LDEPSNDLDV ETLRALEDAL LEFAGSVMVI


 


501
SHDRWFLDRI ATHILACEGD SKWVFFDGNY QEYEADKKRR LGEEGTKPKR


 


551
IKYKPVTR*






m596/a596 99.3% identity in 558 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1877>










g597.seq




1
ATGCTGCTTC ATGTCAGCAA TTCCCTCAAA CAGCTTCAGG AAGAGCGTAT


 


51
CCGCCAAGAA CGTATCCGCC AAGAGCGTAT CCGTCAGGCG CGCGGCAACC


 


101
TTGCTTCCGT CAACCGCAAA CAGCGCGAGG CTTGGGACAA ATTCCAAAAA


 


151
CTCAATACCG AGCTGAACCG TTTGAAAACG GAAGTCGCCG CTACGAAAGC


 


201
GCAGATTTCC CGTTTCGTAT CGGGGAACTA TAAAAACAGC CGGCCGAATG


 


251
CGGTTGCCCT GTTCCTGAAA AACGCCGAAC CGGGTCAGAA AAACCGCTTT


 


301
TTGCGTTATA CGCGTTATGT AAACGCCTCC AATCGGGAAG TTGTCAAGGA


 


351
TTTGGAAAAA CAGCAGAAGG CTTTGGCGGT ACAAGAGCAG AAAATCAACA


 


401
ATGAGCTTGC CCGTTTGAAG AAAATTCAGG CAAACGTGCA ATCCCTGCTG


 


451
AAAAAACAGG GTGTAACCGA TGCGGCGGAA CAGACGGAAA GCCGCAGACA


 


501
GAATGCCAAA ATCTCCAAAG ATGCCCGAAA ACTGCTGGAA CAGAAAGGGA


 


551
ACGAGCAGCA GCTGAACAAG CTCTTGAGCA ATTTGgagaa aaAAAaagcc


 


601
gaacaccgCA TTcaggAtgc ggAagcaaAA agaAAATTGG CTGAagcCaa


 


651
actGgcggca gccgAAAAAG CCAGAAAAGA AGCGGCGCAG CAGAAGGCTG


 


701
AAGCGCGACG TGCGGAAATG TCCAACCTGA CCGCCGAAGA CAGGAACATC


 


751
CAAGCGCCTT CGGTTATGGG TATCGGCAGT GCCGACGgTT TCAGCCGCAT


 


801
GCAGGGACGT TTGAAAAAAC CGGTTGACGG TGTGCCGACC GGGCTTTTCG


 


851
GGCAGAACCG GAGCGGcggC GATGTTTGGA AAGGCGTGTT CTATTCCACT


 


901
GCGCCTGCAA CGGTTGAAAG CATTGCGCcg gGAACggtaa GCTATGCGGA


 


951
cgaGTTGGAC GGCTACGGCA AAGTGGTCGT GATCGATCAC GGCGAGAACT


 


1001
ACATCAGCAT CTATGCCGGT TTGAGCGAAA TTTCCGCCGG CAAGGGTTAT


 


1051
ACGGTCGCGG CAGGAAGCAA AATCGGCACG AGCGGGTCGC TGCCGGACGG


 


1101
GGAAGAGGGG CTTTACCTGC AAATACGTTA TCGAGGTCAG GTGTTGAACC


 


1151
CTTCGGGCTG GATACGTTGA






This corresponds to the amino acid sequence <SEQ ID 1878; ORF 597>:










g597.pep




1
MLLHVSNSLK QLQEERIRQE RIRQERIRQA RGNLASVNRK QREAWDKFQK


 


51
LNTELNRLKT EVAATKAQIS RFVSGNYKNS RPNAVALFLK NAEPGQKNRF


 


101
LRYTRYVNAS NREVVKDLEK QQKALAVQEQ KINNELARLK KIQANVQSLL


 


151
KKQGVTDAAE QTESRRQNAK ISKDARKLLE QKGNEQQLNK LLSNLEKKKA


 


201
EHRIQDAEAK RKLAEAKLAA AEKARKEAAQ QKAEARRAEM SNLTAEDRNI


 


251
QAPSVMGIGS ADGFSRMQGR LKKPVDGVPT GLFGQNRSGG DVWKGVFYST


 


301
APATVESIAP GTVSYADELD GYGKVVVIDH GENYISIYAG LSEISAGKGY


 


351
TVAAGSKIGT SGSLPDGEEG LYLQIRYRGQ VLNPSGWIR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1879>:










m597.seq




1
ATGCTGCTTC ATGTCAGCAA TTCCCTCAAA CAGCTTCAGG AAGAGCGTAT


 


51
CCGCCAAGAG CGTATCCGTC AGGCGCGCGG CAACCTTGCT TCCGTCAACC


 


101
GCAAACAGCG CGAGGCTTGG GACAAGTTCC AAAAACTCAA TACCGAGCTG


 


151
AACCGTTTGA AAACGGAAGT CGCCGCTACG AAAGCGCAGA TTTCCCGTTT


 


201
CGTATCGGGG AACTATAAAA ACAGCCAGCC GAATGCGGTT GCCCTGTTCC


 


251
TGAAAAACGC CGAACCGGGT CAGAAAAACC GCTTTTTGCG TTATACGCGT


 


301
TATGTAAACG CCTCCAATCG GGAAGTTGTC AAGGATTTGG AAAAACAGCA


 


351
GAAGGCTTTG GCGGTACAAG AGCAGAAAAT CAACAATGAG CTTGCCCGTT


 


401
TGAAGAAAAT TCAGGCAAAC GTGCAATCTC TGCTGAAAAA ACAGGGTGTA


 


451
ACCGATGCGG CGGAACAGAC GGAAAGCCGC AGACAGAATG CCAAAATCGC


 


501
CAAAGATGCC CGAAAACTGC TGGAACAGAA AGGGAACGAG CAGCAGCTGA


 


551
ACAAGCTCTT GAGCAATTTG GAGAAGAAAA AGGCCGAACA CCGCATTCAG


 


601
GATGCGGAAG CAAAAAGAAA ATTGGCTGAA GCCAGACTGG CGGCAGCCGA


 


651
AAAAGCCAGA AAAGAAGCGG CGCAGCAGAA GGCTGAAGCA CGACGTGCGG


 


701
AAATGTCCAA CCTGACCGCC GAAGACAGGA ACATCCAAGC GCCTTCGGTT


 


751
ATGGGTATCG GCAGTGCCGA CGGTTTCAGC CGCATGCAAG GACGTTTGAA


 


801
AAAACCGGTT GACGGTGTGC CGACCGGACT TTTCGGGCAG AACCGGAGCG


 


851
GCGGCGATAT TTGGAAAGGC GTGTTCTATT CCACTGCACC GGCAACGGTT


 


901
GAAAGCATTG CGCCGGGAAC GGTAAGCTAT GCGGACGAGT TGGACGGCTA


 


951
CGGCAAAGTG GTCGTGGTCG ATCACGGCGA GAACTACATC AGCATCTATG


 


1001
CCGGTTTGAG CGAAATTTCC GTCGGCAAGG GTTATATGGT CGCGGCAGGA


 


1051
AGCAAAATCG GCTCGAGCGG GTCGCTGCCG GACGGGGAAG AGGGGCTTTA


 


1101
CCTGCAAATA CGTTATCAAG GTCAGGTATT GAACCCTTCG AGCTGGATAC


 


1151
GTTGA






This corresponds to the amino acid sequence <SEQ ID 1880; ORF 597>:










m597.pep




1
MLLHVSNSLK QLQEERIRQE RIRQARGNLA SVNRKQREAW DKFQKLNTEL


 


51
NRLKTEVAAT KAQISRFVSG NYKNSQPNAV ALFLKNAEPG QKNRFLRYTR


 


101
YVNASNREVV KDLEKQQKAL AVQEQKINNE LARLKKIQAN VQSLLKKQGV


 


151
TDAAEQTESR RQNAKIAKDA RKLLEQKGNE QQLNKLLSNL EKKKAEHRIQ


 


201
DAEAKRKLAE ARLAAAEKAR KEAAQQKAEA RRAEMSNLTA EDRNIQAPSV


 


251
MGIGSADGFS RMQGRLKKPV DGVPTGLFGQ NRSGGDIWKG VFYSTAPATV


 


301
ESIAPGTVSY ADELDGYGKV VVVDHGENYI SIYAGLSEIS VGKGYMVAAG


 


351
SKIGSSGSLP DGEEGLYLQI RYQGQVLNPS SWIR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 597 shows 96.1% identity over a 389 aa overlap with a predicted ORF (ORF 597) from N. gonorrhoeae: 

m597/g597 96.1% identity in 389 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1881>










a597.seq




1
ATGCTGCTTC ATGTCAGCAA TTCCCTCAAG CAGCTTCAGG AAGAGCGTAT


 


51
CCGCCAAGAA CGTATCCGCC AAGAGCGTAT CCGTCAGGCG CGCGGCAACC


 


101
TTGCTTCCGT CAACCGCAAA CAGCGCGAGG CTTGGGACAA GTTCCAAAAA


 


151
CTCAATACCG AGCTGAACCG TTTGAAAACG GAAGTCGCCG CTACGAAAGC


 


201
GCAGATTTCC CGTTTCGTAT CGGGGAACTA TAAAAACAGC CAGCCGAATG


 


251
CGGTTGCCCT GTTCCTGAAA AACGCCGAAC CGGGTCAGAA AAACCGCTTT


 


301
TTGCGTTATA CGCGTTATGT AAACGCCTCC AATCGGGAAG TTGTCAAGGA


 


351
TTTGGAAAAA CAGCAGAAGG CTTTGGCGGT ACAAGAGCAG AAAATCAACA


 


401
ATGAGCTTGC CCGTTTGAAG AAAATTCAGG CAAACGTGCA ATCCCTGCTG


 


451
AAAAAACAGG GTGTAACCGA TGCGGCGGAA CAGACGGAAA GCCGCAGACA


 


501
GAATGCCAAA ATCGCCAAAG ATGCCCGAAA ACTGCTGGAA CAGAAAGGGA


 


551
ACGAGCAGCA GCTGAACAAG CTCTTGAGCA ATTTGGAGAA GAAAAAGGCC


 


601
GAACACCGCA TTCAGGATGC GGAAGCAAAA AGAAAATTGG CTGAAGCCAG


 


651
ACTGGCGGCA GCCGAAAAAG CCAGAAAAGA AGCGGCGCAG CAGAAGGCTG


 


701
AAGCACGACG TGCGGAAATG TCCAACCTGA CCGCCGAAGA CAGGAACATC


 


751
CAAGCGCCTT CGGTTATGGG TATCGGCAGT GCCGACGGTT TCAGCCGCAT


 


801
GCAAGGACGT TTGAAAAAAC CGGTTGACGG TGTGCCGACC GGACTTTTCG


 


851
GGCAGAACCG GAGCGGCGGC GATGTTTGGA AAGGCGTGTT CTATTCCACT


 


901
GCACCGGCAA CGGTTGAAAG CATTGCGCCG GGAACGGTAA GCTATGCGGA


 


951
CGAGTTGGAC GGCTACGGCA AAGTGGTCGT GGTCGATCAC GGCGAGAACT


 


1001
ACATCAGCAT CTATGCCGGT TTGAGCGAAA TTTCCGTCGG CAAGGGTTAT


 


1051
ATGGTCGCGG CAGGAAGCAA AATCGGCTCG AGCGGGTCGC TGCCGGACGG


 


1101
GGAAGAGGGG CTTTACCTGC AAATACGTTA TCAAGGTCAG GTATTGAACC


 


1151
CTTCGAGCTG GATACGTTGA






This corresponds to the amino acid sequence <SEQ ID 1882; ORF 597.a>:










a597.pep




1
MLLHVSNSLK QLQEERIRQE RIRQERIRQA RGNLASVNRK QREAWDKFQK


 


51
LNTELNRLKT EVAATKAQIS RFVSGNYKNS QPNAVALFLK NAEPGQKNRF


 


101
LRYTRYVNAS NREVVKDLEK QQKALAVQEQ KINNELARLK KIQANVQSLL


 


151
KKQGVTDAAE QTESRRQNAK IAKDARKLLE QKGNEQQLNK LLSNLEKKKA


 


201
EHRIQDAEAK RKLAEARLAA AEKARKEAAQ QKAEARRAEM SNLTAEDRNI


 


251
QAPSVMGIGS ADGFSRMQGR LKKPVDGVPT GLFGQNRSGG DVWKGVFYST


 


301
APATVESIAP GTVSYADELD GYGKVVVVDH GENYISIYAG LSEISVGKGY


 


351
MVAAGSKIGS SGSLPDGEEG LYLQIRYQGQ VLNPSSWIR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 597 shows 98.5% identity over a 389 aa overlap with a predicted ORF (ORF 597) from N. meningitidis 

m597/a597 98.5% identity in 389 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1883>:










g601.seq




1
ATGTTCCCAA CCGGCAATTT GGTCGACGAA ATTGATGTGC CGAATATAGG


 


51
TCGTCTGAAA GCCACGCTCA TCAACGCGGG CATTCCGACC GTTTTCCTGA


 


101
ACGCCGCCGA CTTGGGCTAC ACGGGCAAAG AGTTGCAGGA CGACATCAAC


 


151
AACGATGCCG CCGCGCTGGA AAAATTTGAA ACCATCCGCG CATATGGCGC


 


201
GCTGAAAATG GGTTTGATCA GCGACGTATC CGAAGCCGCC GCCCGCGCGC


 


251
GCACGCCGAA ACCCGCCTTC GTCGCGCCCG CCGCCGATTA CACCGCCTCC


 


301
AGCGGCAAAA CCGTAAACGC CGCCGACATC GATTTGCCGG TACGCGCCCT


 


351
GAGCATGGGC AAACTGCACC ACGCTATGAT GGGCATCGCC TCGGTCGCCA


 


401
TCGCCGCCGC CGTGCTCGGT ACGCTGGTCA ACCTTGCCGC AGGCGGCGGA


 


451
ACGCGTAAAG AAGTGCGCTT CGGGCATCCG TCAGGTACGC TGCGTGTCGG


 


501
TGCTGCCGCC GAATGTCAGG ACGGACAATG GACGGCCGCc aaagcggtca


 


551
tgaGCCGCAG CGCACgcgtg attatggaaa gttgGGTGCg cgttcccgat


 


601
gattGTTTTT GA






This corresponds to the amino acid sequence <SEQ ID 1884; ORF 601.ng>:










g601.pep




1
MFPTGNLVDE IDVPNIGRLK ATLINAGIPT VFLNAADLGY TGKELQDDIN


 


51
NDAAALEKFE TIRAYGALKM GLISDVSEAA ARARTPKPAF VAPAADYTAS


 


101
SGKTVNAADI DLPVRALSMG KLHHAMMGIA SVAIAAAVLG TLVNLAAGGG


 


151
TRKEVRFGHP SGTLRVGAAA ECQDGQWTAA KAVMSRSARV IMESWVRVPD


 


201
DCF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1885>:










m601.seq




1
ATGTTCCCAA CCGGCAATTT GGTCGATGAA ATTGATGTGC CGAATATAGG


 


51
CCGTTTGAAA GCCACGCTCA TCAACGCGGG CATTCCGACC GTTTTCTTGA


 


101
ATGCCGCCGA CTTGGGCTAC ACAGGCAAAG AGTTGCAAGA CGACATCAAC


 


151
AACGATGCCG CGGCTTTGGA AAAATTCGAG AAAATCCGCG CTTACGGTGC


 


201
GCTGAAAATG GGTCTGATCA GCGACGTATC CGAAGCTGCC GCTCGCGCGC


 


251
ACACGCCGAA AGTCGCCTTC GTCGCGCCCG CCGCCGATTA CACCGCCTCC


 


301
AGTGGCAAAA CCGTGAACGC CGCCGACATC GATTTGCTGG TACGCGCCCT


 


351
GAGCATGGGC AAACTGCACC ACGCGATGAT GGGTACCGCC TCTGTTGCCA


 


401
TTGCGACCGC CGCCGCCGTA CCCGGTACGC TGGTCAACCT TGCCGCAGGC


 


451
GGCGGAACGC GTAAAGAAGT GCGCTTCGGG CATCCTTCCG GCACATTGCG


 


501
CGTCGGTGCA GCCGCCGAAT GTCAGGACGG ACAATGGACG GCCACCAAAG


 


551
CGGTCATGAG CCGTAGCGCA CGCGTGATGA TGGAAGGTTG GGTCAGGGTG


 


601
CCTGAGGATT GTTTTTAA






This corresponds to the amino acid sequence <SEQ ID 1886; ORF 601>:










m601.pep




1
MFPTGNLVDE IDVPNIGRLK ATLINAGIPT VFLNAADLGY TGKELQDDIN


 


51
NDAAALEKFE KIRAYGALKM GLISDVSEAA ARAHTPKVAF VAPAADYTAS


 


101
SGKTVNAADI DLLVRALSMG KLHHAMMGTA SVAIATAAAV PGTLVNLAAG


 


151
GGTRKEVRFG HPSGTLRVGA AAECQDGQWT ATKAVMSRSA RVMMEGWVRV


 


201
PEDCF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 601 shows 94.1% identity over a 205 aa overlap with a predicted ORF (ORF 601.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1887>:










a601.seq




1
ATGTTCCCAA CCGGCAATTT GGTCGATGAA ATTGATGTGC CGAATATAGG


 


51
CCGTTTGAAA GCCACGCTCA TCAACGCGGG CATTCCGACC GTTTTCCTGA


 


101
ATGCCGCCGA CTTGGGCTAC ACGGGCAAAG AGTTGCAAGA CGACATCAAC


 


151
AACGATGCCG CAGCTTTGGA AAAATTCGAG AAAATCCGCG CTTACGGTGC


 


201
GCTGAAAATG GGTCTGATCA GCGACGTATC CGAAGCTGCC GCCCGCGCGC


 


251
ACACGCCGAA AGTCGCCTTC GTCGCGCCCG CCGCCGATTA CACCGCCTCC


 


301
AGTGGCAAAA CCGTGAATGC CGCCGACATC GATTTGCTGG TACGCGCCCT


 


351
GAGCATGGGC AAATTGCACC ACGCGATGAT GGGTACCGCC TCTGTTGCCA


 


401
TTGCGACCGC CGCCGCCGTG CCCGGTACGC TGGTCAACCT TGCCGCAGGC


 


451
GGCGGAACGC GTAAAGAAGT GCGCTTCGGG CATCCTTCCG GCACATTGCG


 


501
CGTCGGTGCA GCCGCCGAAT GTCAGGACGG ACAATGGACG GCCACCAAAG


 


551
CGGTTATGAG CCGCAGCGCA CGCGTGATGA TGGAAGGTTG GGTCAGGGTG


 


601
CCGGAAGATT GTTTTTAA






This corresponds to the amino acid sequence <SEQ ID 1888; ORF 601.a>:










a601.pep




1
MFPTGNLVDE IDVPNIGRLK ATLINAGIPT VFLNAADLGY TGKELQDDIN


 


51
NDAAALEKFE KIRAYGALKM GLISDVSEAA ARAHTPKVAF VAPAADYTAS


 


101
SGKTVNAADI DLLVRALSMG KLHHAMMGTA SVAIATAAAV PGTLVNLAAG


 


151
GGTRKEVRFG HPSGTLRVGA AAECQDGQWT ATKAVMSRSA RVMMEGWVRV


 


201
PEDCF*






m601/a601 100.0% identity in 205 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1889>:










g602.seq




1
ATGTTGCTCC ATCAATGCGA CAAAGCGCGA CATATGCGTC CCTTTCTGCT


 


51
CGGCGGGCAG ATAAACCGTC ATCGTCAGGC GAGCAACCGT GGATTGTGTT


 


101
CCTTCGGCGG TTTTCAGGGT AATCGGGAAG CGCAGGTCTT TAATGCCGAC


 


151
CTGATTGATC GGCAGGTTGC GCAAATCTCT GCTGGATTGC ACGTCTGCAA


 


201
TGGCGTTCAT GCGTTGTTTG TCCTTAATAT TCAGATAATT ATTGAGATGT


 


251
GTGTATTGTA TGGCAGGcag atgccgtctg aAAAAacgct gtcggCCGCC


 


301
TGCCTGCAAA TgcgagattA TATCACTTGC TTTtggcgGC TGCATTGA






This corresponds to the amino acid sequence <SEQ ID 1890; ORF 602.ng>:










g602.pep




1
MLLHQCDKAR HMRPFLLGGQ INRHRQASNR GLCSFGGFQG NREAQVFNAD


 


51
LIDRQVAQIS AGLHVCNGVH ALFVLNIQII IEMCVLYGRQ MPSEKTLSAA


 


101
CLQMRDYITC FWRLH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1891>:










m602.seq




1
ATGTTGCTCC ATCAATGCGA CAAAACGCGA CATATGCGTC CCCTTCTGCT


 


51
CAGCAGGCAG GTAAACCGTC ATGGTCAGAC GGGCAATGGT GGACTGGATG


 


101
CCTTCTGCAG TTTGCAGGGT AATCGGAAAG CGCAGGTCTT TGATACCGAC


 


151
CTGATTGATC GGCAGATTGC GCAAATCTCG GCTGGATTGC ACGTCTGCAA


 


201
TAGTGTTCAT GAGTTGTTTT TCCTTAATAT TCATGTAATT GTTGAGATGT


 


251
GTGCATGGTA TGGCGTTTCC GCCGGGGAAT ATACCGTCAA TCTGCAAATG


 


301
CGAGATTATA TCACTCGCTT TTAGCAGCTG CATTGA






This corresponds to the amino acid sequence <SEQ ID 1892; ORF 602>:










m602.pep




1
MLLHQCDKTR HMRPLLLSRQ VNRHGQTGNG GLDAFCSLQG NRKAQVFDTD


 


51
LIDRQIAQIS AGLHVCNSVH ELFFLNIHVI VEMCAWYGVS AGEYTVNLQM


 


101
RDYITRF*QL H*






m602/g602 65.2% identity in 115 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1893>:










a602.seq




1
ATGTTGCTCC ATCAATGCGA CAAAGCGCGA CATATGCGTA CCCTTCTGCT


 


51
CGGCAGGCAG GTAAACCGTC ATGGTCAGAC GGGCAACTGT GGACTGGATG


 


101
CCTTCTGCAG TTTGCAGGGT AATCGGAAAG CGCAGGTCTT TGATACCGAC


 


151
CTGATTGATC GGCAGATTGC GCAAATCTCG GCTGGATTGC ACGTCTGCAA


 


201
TAGTGTTCAT GAGTTGTTTT TCCTTAATAT TCATGTAATT GTTGAGATGT


 


251
GTGCATGGTA TGGCGTTTCC ACCGGGGAAT ATACCGTCAA TCTGCAAATG


 


301
CGAGATTATA TCACTCGCTT TTAGCAGCTG CATTGA






This corresponds to the amino acid sequence <SEQ ID 1894; ORF 602.a>:










a602.pep




1
MLLHQCDKAR HMRTLLLGRQ VNRHGQTGNC GLDAFCSLQG NRKAQVFDTD


 


51
LIDRQIAQIS AGLHVCNSVH ELFFLNIHVI VEMCAWYGVS TGEYTVNLQM


 


101
RDYITRF*QL H*






m602/a602 95.5% identity in 111 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1895>:










g603.seq




1
ATGGATTCCC GCCTGCGTGG GAATGACGCT AGGAAATACG GCATACGCTT


 


51
TGCCCAAAGA GGCCGTCTGA AACACACTCC GCCCAACGCC CATCCTTTTT


 


101
CAGACGGCCC CGCACCAAAA AAACAACCAC AAACTACAAG GAGAAACATC


 


151
ATGTCCGACC AACTCATTCT TGTCCTGAAC TGCGTCAGTT CATCGCTCAA


 


201
AGGCGCCGTT ATCGACCGCA AAAGCGGCAG CGTCGTCCTA AGCTGCCTCG


 


251
GGGAACGCCT GACTACGCCC GAAGCCGTCA TTACCTTCAA CAAAGACGGC


 


301
AACAAACGCC AAGTTCCCCT GAGCGGCCGC AACTGCCACG CCGGCGCGGT


 


351
GGGTATGCTG TTGAACGAAC TGGAAAAACA CGGACTGCAC GACCGCATCA


 


401
AAGCCATCGG CCGCCGCATC GCCCACGGCG GCGAAAAATA TCACGAGTCC


 


451
GTCCTCATCG ACCAAGACGT CCTTGACGAA CTGAAAGCCT GCATCCCGTT


 


501
CGCCCCGCTG CACAACCCCG CCAACATCAG CGGCATCCTC GCCGCGCAGG


 


551
AACACTTTCC CGGCCTGCCC AACGTCGGCG TGATGGACAC CTCGTTCCAC


 


601
CAAACCATGC CGGAGCGGGC CTACACTTAT GCCGTGCCGC GCGAATTGCG


 


651
CAAAAAATAC GCCTTCCGCC GCTACGGTTT CCACGGTACC GGTATGCGTT


 


701
ACGTCGCCCC TGAAGCCGCA CGCATCTTGG GCAAACCTct ggaaGACATC


 


751
CGCATGATTA TTGCCCACTT AGGCAACGGC GCATCTATTA CCGCCGTCAA


 


801
AAACGGCAAA TCCGTCGATA CCGGTATGGG TTTCACGCCG ATCGAAGGTT


 


851
TGGTAATGGG TACACGTTGC GGCGACACCG ATCCGGGCGT ATACAGCTAT


 


901
CCGACTTTCC ACGCAGGGAT GGATGTTGCC CAAGTTGATG AAATGCTGAA


 


951
CGAAAAATCA GGTTTCCCCG GTATTTCcgA actTCCCAAC GACTGCCGCA


 


1001
CCCTCGAAAT CGCCGCCGAC GAAGGCCGCG AAGGCGCGCG CCTCGCCCTc


 


1051
gaAGTCATGA CCTGCCGCCT CGCCAAATAC ATCGCTTCGA TGGCTGTGGC


 


1101
CTGCGGCAGT GTTGACGCAC TCGTGTTCAC CGGCGGTATC GGCGAAAACT


 


1151
CGCGTAATAT CCGTGCCAAA ACCGTTTCCT ATCTTGATTT CTTGGGTCTG


 


1201
CACATCGACA CCAAAGCCAA TATGGAAAAA CGCTACGGCA ATTCGGGCAT


 


1251
TATCAGCCCG ACCGATTCTT CTCCGGCTGT TTTGGTCGTC CCGACCAATG


 


1301
AAGAACTGAT GATTGCCTGC GACACTGCCG AACTTGCCGG CATCTTGTAG






This corresponds to the amino acid sequence <SEQ ID 1896; ORF 603.ng>:










g603.pep




1
MDSRLRGNDA RKYGIRFAQR GRLKHTPPNA HPFSDGPAPK KQPQTTRRNI


 


51
MSDQLILVLN CVSSSLKGAV IDRKSGSVVL SCLGERLTTP EAVITFNKDG


 


101
NKRQVPLSGR NCHAGAVGML LNELEKHGLH DRIKAIGRRI AHGGEKYHES


 


151
VLIDQDVLDE LKACIPFAPL HNPANISGIL AAQEHFPGLP NVGVMDTSFH


 


201
QTMPERAYTY AVPRELRKKY AFRRYGFHGT GMRYVAPEAA RILGKPLEDI


 


251
RMIIAHLGNG ASITAVKNGK SVDTGMGFTP IEGLVMGTRC GDTDPGVYSY


 


301
PTFHAGMDVA QVDEMLNEKS GFPGISELPN DCRTLEIAAD EGREGARLAL


 


351
EVMTCRLAKY IASMAVACGS VDALVFTGGI GENSRNIRAK TVSYLDFLGL


 


401
HIDTKANMEK RYGNSGIISP TDSSPAVLVV PTNEELMIAC DTAELAGIL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1897>:










m603.seq




1
CTGTCCTCGC GTAGGCGGGG ACGGAATAAC GATAGAAAAT GCGGCATACG


 


51
CTTTGCCCAA AGAGGCCGTC TGAAACACCT TGCGCCTGAT GTCTGC.CTT


 


101
TTTCAGACGA CCCCACACTA AAAAAACAAC CACAAACTAC AAGGAGAAAC


 


151
ATCATGTCCG ACCAACTCAT CCTCGTTCTG AACTGCGGCA GTTCATCGCT


 


201
CAAAGGCGCC GTTATCGACC GAmAAAGCGG CAGCGTCGTC CTAAGCTGCC


 


251
TCGGCGAACG cCtGACCACG CCCGAAGCCG TCATTACGTT CAACAAAGAC


 


301
GGCAACAAAC GCCAAGTTCC CCTGAGCGGC CGAAATTGCC ACGCCGGCGC


 


351
GGTGGGTATG CTTTTGAACG AACTGGAAAA ACACGGTCTG CACGACCGCA


 


401
TCAAAGCCAT CGGCCACCGC ATCGCCCACG GCGGCGAAAA ATACAGCGAG


 


451
TCTGTTTTGA TCGACCAGGC CGTAATGGAC GAACTCAATG CCTGCATTCC


 


501
GCTTGCGCCG CTGCACAACC CCGCCAACAT CAGCGGCATC CTTGCCGCAC


 


551
AGGAACATTT CCCCGGTCTG CCCAATGTCG GCGTGATGGA TACTTCGTTC


 


601
CACCAAACCA TGCCGGAGCG TGCCTACACT TATGCCGTGC CGCGCGAGTT


 


651
GCGTAAAAAA TACGCTTTCC GCCGCTACGG TTTCCACGGC ACCAGTATGC


 


701
GTTACGTTGC CCCTGAAGCC GCACGCATCT TGGGCAAACC TCTGGAAGAC


 


751
ATCCGCATGA TTATTGCCCA CTTAGGCAAC GGCGCATCCA TTACCGCCAT


 


801
CAAAAACGGC AAATCCGTCG ATACCAGTAT GGGTTTCACG CCGATCGAAG


 


851
GTTTGGTAAT GGGTACACGT TGCGGCGACA TCGATCCGGG CGTATACAGC


 


901
TATCTGACTT CCCACGCCGG GATGGATGTT GCCCAAGTGG ATGAAATGCT


 


951
GAACAAAAAA TCAGGTTTGC TCGGTATTTC CGAACTTTCC AACGACTGCC


 


1001
GCACCCTCGA AATCGCCGCC GACGAAGGCC ACGAAGGCGC GCGCCTCGCC


 


1051
CTCGAAGTCA TGACCTACCG CCTCGCCAAA TACATCGCTT CGATGGCTGT


 


1101
GGGCTGCGGC GGCGTTGACG CACTCGTGTT CACCGGCGGT ATCGGCGAAA


 


1151
ACTCGCGTAA TATCCGTGCC AAAACCGTTT CCTATCTTGA TTTCTTGGGT


 


1201
CTGCACATCG ACACCAAAGC CAATATGGAA AAACGCTACG GCAATTCGGG


 


1251
CATTATCAGC CCGACCGATT CTTCTCCGGC TGTTTTGGTT GTCCCGACCA


 


1301
ATGAAGAACT GATGATTGCC TGCGACACTG CCGAACTTGC CGGCATCTTG


 


1351
TAG






This corresponds to the amino acid sequence <SEQ ID 1898; ORF 603>:










m603.pep




1
LSSRRRGRNN DRKCGIRFAQ RGRLKHLAPD VCXFSDDPTL KKQPQTTRRN


 


51
IMSDQLILVL NCGSSSLKGA VIDRXSGSVV LSCLGERLTT PEAVITFNKD


 


101
GNKRQVPLSG RNCHAGAVGM LLNELEKHGL HDRIKAIGHR IAHGGEKYSE


 


151
SVLIDQAVMD ELNACIPLAP LHNPANISGI LAAQEHFPGL PNVGVMDTSF


 


201
HQTMPERAYT YAVPRELRKK YAFRRYGFHG TSMRYVAPEA ARILGKPLED


 


251
IRMIIAHLGN GASITAIKNG KSVDTSMGFT PIEGLVMGTR CGDIDPGVYS


 


301
YLTSHAGMDV AQVDEMLNKK SGLLGISELS NDCRTLEIAA DEGHEGARLA


 


351
LEVMTYRLAK YIASMAVGCG GVDALVFTGG IGENSRNIRA KTVSYLDFLG


 


401
LHIDTKANME KRYGNSGIIS PTDSSPAVLV VPTNEELMIA CDTAELAGIL


 


451
*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 603 shows 91.6% identity over a 450 aa overlap with a predicted ORF (ORF 603.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1899>:










a603.seq




1
CTGTCCTCGC GTAGGCGGGG ACGGAATAAC GATAGAAAAT GCGGCATACG


 


51
CTTTGCCCAA AGAGGCCGTC TGAAACACAC TCCGCCCAAC GCCCATCCTT


 


101
TTTCAGACGA CCCCACACC. AAAAAACAAC CACAAACTAC AAGGAGAAAC


 


151
ATCATGTCCG ACCAACTCAT TCTTGTTCTG AACTGCGGCA GTTCATCGCT


 


201
CAAAGGTGCC GTTATCGACC GCAAAAGCGG CAGCGTCGTC CTAAGCTGCC


 


251
TCGGCGAACG CCTGACCACG CCCGAAGCCG TCATTACGTT CAGCAAAGAC


 


301
GGCAACAAAC GCCAAGTTCC CCTGAGCGGC CGGAACTGCC ACGCCGGCGC


 


351
GGTGGGTATG CTGTTGAACG AACTGGAAAA ACACGAACTG CACGACCGCA


 


401
TTCAAGCCGT CGGCCACCGC ATCGCCCACG GCGGCGAAAA ATACAGCGAG


 


451
TCTGTTTTGA TCGACCAGGC CGTAATGGAC GAACTCAATG CCTGCATTCC


 


501
GCTTGCGCCG CTGCACAACC CCGCCAACAT CAGCGGCATC CTCGCCGCAC


 


551
AGGAACATTT CCCCGGTCTG CCCAATGTCG GCGTGATGGA TACTTCGTTC


 


601
CACCAAACCA TGCCGGAGCG TGCCTACACT TATGCCGTGC CGCGCGAGTT


 


651
GCGTAAAAAA TACGCTTTCC GCCGCTACGG TTTCCACGGC ACCAGTATGC


 


701
GTTACGTTGC CCCTGAAGCC GCATGCATCT TGGGCAAACC TCTGGAAGAC


 


751
ATCCGCATGA TTATTGCCCA CTTAGGCAAC GGCGCATCCA TTACCGCCAT


 


801
CAAAAACGGC AAATCCGTCG ATACCAGTAT GGGTTTCACG CCGATCGAAG


 


851
GTTTGGTAAT GGGTACGCGC TGCGGCGATA TCGACCCGGG CGTATACAGC


 


901
TATCTGACTT CACACGCCGG TTTGGATGTT GCACAAGTTG ATGAAATGCT


 


951
GAATAAAAAA TCAGGCTTGC TCGGTATTTC CGAACTCTCC AACGACTGCC


 


1001
GCACCCTCGA AATCGCCGCC GACGAAGGCC ACGAAGGCGC GCGCCTCGCC


 


1051
CTCGAAGTTA TGACCTACCG CCTCGCCAAA TACATCGCTT CGATGGCTGT


 


1101
GGGCTGCGGC GGCGTTGACG CACTCGTGTT CACCGGCGGT ATCGGCGAAA


 


1151
ACTCGCGTAA TATCCGTGCC AAAACCGTTT CCTATCTTGA TTTCTTGGGT


 


1201
CTGCACATCG ACACCAAAGC CAATATGGAA AAACGCTACG GCAATTCGGG


 


1251
TATTATCAGC CCGACCGATT CTTCTCCGGC TGTTTTGGTT GTCCCGACCA


 


1301
ATGAAGAACT GATGATTGCC TGCGACACTG CCGAACTTGT CGGCATCTTG


 


1351
TAG






This corresponds to the amino acid sequence <SEQ ID 1900; ORF 603.a>:










a603.pep




1
LSSRRRGRNN DRKCGIRFAQ RGRLKHTPPN AHPFSDDPTX KKQPQTTRRN


 


51
IMSDQLILVL NCGSSSLKGA VIDRKSGSVV LSCLGERLTT PEAVITFSKD


 


101
GNKRQVPLSG RNCHAGAVGM LLNELEKHEL HDRIQAVGHR IAHGGEKYSE


 


151
SVLIDQAVMD ELNACIPLAP LHNPANISGI LAAQEHFPGL PNVGVMDTSF


 


201
HQTMPERAYT YAVPRELRKK YAFRRYGFHG TSMRYVAPEA ACILGKPLED


 


251
IRMIIAHLGN GASITAIKNG KSVDTSMGFT PIEGLVMGTR CGDIDPGVYS


 


301
YLTSHAGLDV AQVDEMLNKK SGLLGISELS NDCRTLEIAA DEGHEGARLA


 


351
LEVMTYRLAK YIASMAVGCG GVDALVFTGG IGENSRNIRA KTVSYLDFLG


 


401
LHIDTKANME KRYGNSGIIS PTDSSPAVLV VPTNEELMIA CDTAELVGIL


 


451
*






m603/a603 96.7% identity in 450 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1901>:










g604.seq




1
ATGCCCGAAG CGCACTTCTT TACGCGTTCC GCCGCCTGCG GCAAGGTTGA


 


51
CCAGCGTACC GAGCACGGCG GCGGCGATGG CGACCGAGGC GATGCCCATC


 


101
ATAGCGTGGT GCAGTTTGCC CATGCTCAGG GCGCGTACCG GCAAATCGAT


 


151
GTCGGCGGCG TTTACGGTTT TGCCGCTGGA GGCGGTGTAA TCGGCGGCGG


 


201
GCGCGACGAA GGCGGGTTTC GGCGTGCGCG CGCGGGCGGC GGCTTCGGAT


 


251
ACGTCGCTGA TCAAACCCAT TTTCAGCGCG CCATATGCGC GGATGGTTTC


 


301
AAATTTTTCC AGCGCGGCGG CATCGTTGTT GATGTCGTCC TGCAACTCTT


 


351
TGCCCGTGTA GCCCAAGTCG GCGGCGTTCA GGAAAACGGT CGGAATGCCC


 


401
GCGTTGATGA GCGTGGCTTT CAGACGACCT ATATTCGGCA CATCAATTTC


 


451
GTCGACCAAA TTGCCGGTTG GGAACATACT GCCTTcgcCG TCGGCTGGAT


 


501
CTAA






This corresponds to the amino acid sequence <SEQ ID 1902; ORF 604.ng>:










g604.pep




1
MPEAHFFTRS AACGKVDQRT EHGGGDGDRG DAHHSVVQFA HAQGAYRQID


 


51
VGGVYGFAAG GGVIGGGRDE GGFRRARAGG GFGYVADQTH FQRAICADGF


 


101
KFFQRGGIVV DVVLQLFARV AQVGGVQENG RNARVDERGF QTTYIRHINF


 


151
VDQIAGWEHT AFAVGWI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1903>:










m604.seq




1
ATGCCCGAAG CGCACTTCTT TACGCGTTCC GCCGCCTGCG GCAAGGTTGA


 


51
CCAGCGTACC GGGTACGGCG GCGGCGGTCG CAATGGCAAC AGAGGCGGTA


 


101
CCCATCATCG CGTGGTGCAG TTTGCCCATG CTCAGGGCGC GTACCAGCAA


 


151
ATCGATGTCG GCGGCGTTCA CGGTTTTGCC ACTGGAGGCG GTGTAATCGG


 


201
CGGCGGGCGC GACGAAGGCG ACTTTCGGCG TGTGCGCGCG AGCGGCAGCT


 


251
TCGGATACGT CGCTGATCAG ACCCATTTTC AGCGCACCGT AAGCGCGGAT


 


301
TTTCTCGAAT TTTTCCAAAG CCGCGGCATC GTTGTTGATG TCGTCTTGCA


 


351
ACTCTTTGCC TGTGTAGCCC AAGTCGGCGG CATTCAAGAA AACGGTCGGA


 


401
ATGCCCGCGT TGATGAGCGT GGCTTTCAAA CGGCCTATAT TCGGCACATC


 


451
AATTTCATCG ACCAAATTGC CGGTTGGGAA CATACTGCCT TCGCCGTCGG


 


501
CTGGATC






This corresponds to the amino acid sequence <SEQ ID 1904; ORF 604>:










m604.pep




1
MPEAHFFTRS AACGKVDQRT GYGGGGRNGN RGGTHHRVVQ FAHAQGAYQQ


 


51
IDVGGVHGFA TGGGVIGGGR DEGDFRRVRA SGSFGYVADQ THFQRTVSAD


 


101
FLEFFQSRGI VVDVVLQLFA CVAQVGGIQE NGRNARVDER GFQTAYIRHI


 


151
NFIDQIAGWE HTAFAVGWI






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 604 shows 83.4% identity over a 169 aa overlap with a predicted ORF (ORF 604.ng) from N. gonorrhoeae: 

m604/g604





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1905>:










a604.seq




1
ATGCCCGAAG CGCACTTCTT TACGCGTTCC GCCGCCTGCG GCAAGGTTGA


 


51
CCAGCGTACC GGGCACGGCG GCGGCGGTCG CAATGGCAAC AGAGGCGGTA


 


101
CCCATCATCG CGTGGTGCAA TTTGCCCATG CTCAGGGCGC GTACCAGCAA


 


151
ATCGATGTCG GCGGCATTCA CGGTTTTGCC ACTGGAGGCG GTGTAATCGG


 


201
CGGCGGGCGC GACGAAGGCG ACTTTCGGCG TGTGCGCGCG GGCGGCAGCT


 


251
TCGGATACGT CGCTGATCAG ACCCATTTTC AGCGCACCGT AAGCGCGGAT


 


301
TTTCTCGAAT TTTTCCAAAG CTGCGGCATC GTTGTTGATG TCGTCTTGCA


 


351
ACTCTTTGCC CGTGTAGCCC AAGTCGGCGG CATTCAGGAA AACGGTCGGA


 


401
ATGCCCGCGT TGATGAGCGT GGCTTTCAAA CGGCCTATAT TCGGCACATC


 


451
AATTTCATCG ACCAAATTGC CGGTTGGGAA CATACTGCCT TCGCCGTCGG


 


501
CTGGATCAAG AAATTCGATT TGTACTTCGG CTGCCGGGAA CGTTACGCCG


 


551
TCGAGCTCAA AATCGCCTGT TTCCAAAACT GCGCCGTTTT GCATCGGTAC


 


601
ATGGGCAATA ATGGTTTTGC CGATGTTTTT CTGCCAGATT TTGACTGTGC


 


651
AGATGCCGTC TGA






This corresponds to the amino acid sequence <SEQ ID 1906; ORF 604.a>:










a604.pep




1
MPEAHFFTRS AACGKVDQRT GHGGGGRNGN RGGTHHRVVQ FAHAQGAYQQ


 


51
IDVGGIHGFA TGGGVIGGGR DEGDFRRVRA GGSFGYVADQ THFQRTVSAD


 


101
FLEFFQSCGI VVDVVLQLFA RVAQVGGIQE NGRNARVDER GFQTAYIRHI


 


151
NFIDQIAGWE HTAFAVGWIK KFDLYFGCRE RYAVELKIAC FQNCAVLHRY


 


201
MGNNGFADVF LPDFDCADAV *






m604/a604 97.0% identity in 169 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1907>:










g605.seq




1
ATGATGACCG AAATGCAACA ACGCGCCCAA CTGCACCGCC AAATTTGGAA


 


51
AATCGCCGAC GAAGTACGCG GCGCGGTGGA TGGCTGGGAC TTTAAACAAT


 


101
ACGTTCTCGG CACACTTTTC TACCGCTTTA TCAGCGAAAA CTTCACCGAC


 


151
TATATGCAGG CCGGCGACAG CAGCATTGAT TACGCCGCta tGCCGGACAG


 


201
CATCATCACG CCCGAAATCA AAGACGATgc cgtcaaagtc aaAGGCTATT


 


251
TCATCtacCc cgGCCAGCTT TTTTgcaata ttgccgccga agcCCATCAA


 


301
AACGAAGAGC TCAACACCAA GCTGAAAGAa atCTTTACCG CGATTGAAAG


 


351
CTCCGCCTCC GGCTAcccgT CCGAACAAGG CATCAAAGGC TTGTTTGACG


 


401
ACTTCgACAC CACCAGCAGC CGGCTCGGCA GCACCGTTGC CGACAAAAAC


 


451
AAACGCCTTG CCGCCGTCCT TAAAGGCGTG GCGGAACTCG ATTTCGGCAA


 


501
TTTTGAAGAC CACCGCATCG ACCTTTTCGG TGATGCCTAC GAATACCTGA


 


551
TTTCCAACTA CGCcgcCAAC GCAGGCAAAT CCGGCGGCGA ATTTTTCACC


 


601
CCGCAAAGCG TCTCCAAGCT GATTGCGCGG CTGGCGGTGC ACGGGCAGGA


 


651
GAAAGTCAAC AAAATCTACG ACCCCGCCTG CGGCTCGGGC AGCCTGCTCT


 


701
TGCAGGCGAA AAAACAGTTT GACGAACACA TCATCGAAGA AGGCTTCTTC


 


751
GGGCAGGAAA TCAACCACAC CACCTACAAC CTCGCCCGCA TGAATATGTT


 


801
TCTGCACAAC GTCAATTACA ACAAATTCCA CATCGAATTG GGCGACACGC


 


851
TGACCAACCC CAAACTCAAA GACAGCAAAC CCTTTGATGC CGTCGTCTCC


 


901
AATCCGCCCT ATTCCATCGA CTGGATAGGC AGCGACGACC CCACCTtgaT


 


951
CAACGACGAC CGCTTTGCCC CCGCAGGCGT ACTCGCACCG AAATCCAAAG


 


1001
CCGATTTTGC CTTCATCCTG CACGCACTGA ACTACCTTTC CGGCAGAGGC


 


1051
CGCGCCGCTA TCGTCTCATT CCCCGGCATT TTCTATCGCG GCGGCGCAGA


 


1101
GCAGAAAATc CGCCAATATC TGGTGGAGGG CAACTATGTG GAAACCGTGA


 


1151
TTGCCCTTGC GCCCAATCTC TTTTACGGCA CCTGCATCGC CGTCAATATC


 


1201
CTGGTTTTGT CCAAACACAA AGACAATACC GACATCCAAT TCATCGACGC


 


1251
AAGCGGCTTC TTTAAAAAAG AAACCAACAA CAACGTCTTA ACCGAAGAAC


 


1301
ACATTGCCGA AATCGTCAAA CTCTTCGCCG ACAAAGCCGA TGTGCCGCAT


 


1351
ATCGCCCAAA ACGCCGCCCA GCAAACCGTC AAAGACAACG GCTACAACCT


 


1401
CGCCGTCAGC AGCTATGTCG AAGCCGAAGA CACCCGCGAG GTCATCGACA


 


1451
TCAGACAGCT CAACGCCGAA ATCAGCGAAA CCgtcgCcaa AATCGAACGG


 


1501
CTGCGGCGTG AAATTGACGA AGTGATTGCA GAGATTGAAA CCTAG






This corresponds to the amino acid sequence <SEQ ID 1908; ORF 605.ng>:










g605.pep




1
MMTEMQQRAQ LHRQIWKIAD EVRGAVDGWD FKQYVLGTLF YRFISENFTD


 


51
YMQAGDSSID YAAMPDSIIT PEIKDDAVKV KGYFIYPGQL FCNIAAEAHQ


 


101
NEELNTKLKE IFTAIESSAS GYPSEQGIKG LFDDFDTTSS RLGSTVADKN


 


151
KRLAAVLKGV AELDFGNFED HRIDLFGDAY EYLISNYAAN AGKSGGEFFT


 


201
PQSVSKLIAR LAVHGQEKVN KIYDPACGSG SLLLQAKKQF DEHIIEEGFF


 


251
GQEINHTTYN LARMNMFLHN VNYNKFHIEL GDTLTNPKLK DSKPFDAVVS


 


301
NPPYSIDWIG SDDPTLINDD RFAPAGVLAP KSKADFAFIL HALNYLSGRG


 


351
RAAIVSFPGI FYRGGAEQKI RQYLVEGNYV ETVIALAPNL FYGTCIAVNI


 


401
LVLSKHKDNT DIQFIDASGF FKKETNNNVL TEEHIAEIVK LFADKADVPH


 


451
IAQNAAQQTV KDNGYNLAVS SYVEAEDTRE VIDIRQLNAE ISETVAKIER


 


501
LRREIDEVIA EIET*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1909>:










m605.seq




1
ATGATGACCG AAATGCAACA ACGCGCCCAA CTGCACCGCC AAATTTGGAA


 


51
AATTGCCGAC GAAGTACGCG GCGCGGTGGA TGGCTGGGAC TTTAAACAAT


 


101
ACGTTCTCGG CACACTTTTC TACCGCTTTA TCAGCGAAAA CTTCACCGAC


 


151
TATATGCAGG CAGGCGACAG CAGTATTGAT TACGCCGCTA TGCCGGACAG


 


201
CATCATCACG CCCGAAATCA AAGACGATGC CGTCAAAGTT AAAGGCTATT


 


251
TCATCTACCC CGGCCAGCTT TTTTGCAATA TTGCCGCCGA AGCCCATCAA


 


301
AACGAAGAGC TCAACACCAA GCTGAAAGAA ATTTTTACCG CGATTGAAAG


 


351
CTCCGCCTCC GGCTATCCGT CCGAACAGGA CATCAAAGGC CTGTTTGACG


 


401
ACTTCGACAC CACCAGCAGC CGGCTCGGCA GCACTGTTGC CGACAAGAAC


 


451
AAACGCCTTG CCGCCGTCCT CAAAGGCGTG GCGGAACTCG ATTTCGGCAA


 


501
TTTTGAAAAC CACCACATCG ACCTTTTCGG CGATGCCTAC GAATACCTGA


 


551
TTTCCAACTA CGCTGCCAAC GCAGGCAAAT CCGGCGGCGA ATTTTTCACC


 


601
CCGCAAAGCG TATCCAAGCT GATTGCGCGG CTGGCGGTGC ACGGACAGGA


 


651
GAAAGTCAAC AAAATCTACG ACCCAGCTTG CGGCTCGGGC AGTCTGCTCT


 


701
TGCAGGCGAA AAAACAGTTT GACGAGCACA TCATCGAAGA AGGCTTCTTC


 


751
GGGCAGGAAA TCAACCACAC CACCTACAAC CTCGCCCGCA TGAACATGTT


 


801
CCTGCACAAC GTCAATTACA ACCAATTCCA CATCGAATTG GGCGACACAC


 


851
TGACCAACCC AAAGCTCAAA GACAGCAAAC CCTTTGATGC CATCGTTTCC


 


901
AATCCGCCTT ATTCCATCAA CTGGATAGGC AGCGACGACC CCACCTTAAT


 


951
CAACGACGAC CGCTTTGCCC CCGCAGGCGT ACTTGCCCCG AAATCCAAAG


 


1001
CCGATTTTGC CTTCATCCTG CACGCACTGA ACTACCTTTC CGGCAGAGGC


 


1051
CGCGCCGCCA TCGTCTCATT CCCCGGCATT TTCTATCGCG GCGGCGCAGA


 


1101
ACAGAAAATC CGCCAATATC TGGTGGAGGG CAACTACGTG GAAACCGTGA


 


1151
TTGCCCTTGC GCCCAATCTC TTTTACGGCA CCGGCATCGC CGTCAATATC


 


1201
CTGGTTTTGT CCAAACACAA AGACAATACC GACATCCAAT TCATCGACGC


 


1251
AAGCGGCTTC TTTAAAAAAG AAACCAACAA CAACGTCTTA ATCGAAGAAC


 


1301
ACATTGCTGA AATCGTCAAA CTCTTCGCCG ATAAAGCCGA TGTGCCGCAT


 


1351
ATCGCCCAAA ACGCTGCCCA GCAAACCGTC AAAGACAACG GCTACAACCT


 


1401
CGCCGTCAGC AGCTATGTCG AAGCCGAAGA CACACGCGAA ATTATCGACA


 


1451
TCAAACAGCT CAACGCCGAA ATCGGCGAAA CCGTCGCCAA AATCGAACGG


 


1501
CTGCGGCGTG AAATTGACGA AGTGATTGCA GAGATTGAAG CATGA






This corresponds to the amino acid sequence <SEQ ID 1910; ORF 605>:










m605.pep




1
MMTEMQQRAQ LHRQIWKIAD EVRGAVDGWD FKQYVLGTLF YRFISENFTD


 


51
YMQAGDSSID YAAMPDSIIT PEIKDDAVKV KGYFIYPGQL FCNIAAEAHQ


 


101
NEELNTKLKE IFTAIESSAS GYPSEQDIKG LFDDFDTTSS RLGSTVADKN


 


151
KRLAAVLKGV AELDFGNFEN HHIDLFGDAY EYLISNYAAN AGKSGGEFFT


 


201
PQSVSKLIAR LAVHGQEKVN KIYDPACGSG SLLLQAKKQF DEHIIEEGFF


 


251
GQEINHTTYN LARMNMFLHN VNYNQFHIEL GDTLTNPKLK DSKPFDAIVS


 


301
NPPYSINWIG SDDPTLINDD RFAPAGVLAP KSKADFAFIL HALNYLSGRG


 


351
RAAIVSFPGI FYRGGAEQKI RQYLVEGNYV ETVIALAPNL FYGTGIAVNI


 


401
LVLSKHKDNT DIQFIDASGF FKKETNNNVL IEEHIAEIVK LFADKADVPH


 


451
IAQNAAQQTV KDNGYNLAVS SYVEAEDTRE IIDIKQLNAE IGETVAKIER


 


501
LRREIDEVIA EIEA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae ORF 605 shows 97.9% identity over a 513 aa overlap with a predicted ORF (ORF 605.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1911>:










a605.seq




1
ATGATGACCG AAATACAACA ACGCGCCCAA CTGCACCGCC AAATTTGGAA


 


51
AATTGCCGAC GAAGTACGCG GCGCGGTGGA TGGCTGGGAC TTCAAACAAT


 


101
ACGTTCTCGG CACACTTTTC TACCGCTTTA TCAGCGAAAA CTTTACCGAC


 


151
TATATGCAGG CAGGCGACAG CAGTATTGAT TACGCCGCTA TGCCGGACAG


 


201
CATCATCACG CCCGAAATCA AAGACGATGC CGTCAAAGTC AAAGGCTATT


 


251
TCATCTACCC CGGCCAGCTT TTTTGCAATA TTGCCGCCGA AGCCCATCAA


 


301
AACGAAGAGC TCAACACCAA GCTGAAAGAA ATTTTTACCG CGATTGAAAG


 


351
CTCCGCCTCC GGCTATCCGT CCGAACAAGA CATTAAAGGC CTGTTTGACG


 


401
ACTTCGACAC CACCAGCAGC CGGCTCGGCA GCACCGTTGC CGACAAGAAC


 


451
AAACGCCTTG CCGCCGTCCT AAAAGGCGTG GCGGAACTCG ATTTCGGCAG


 


501
TTTTGAAGAC CACCACATCG ACCTTTTCGG CGATGCCTAC GAATACCTGA


 


551
TTTCCAACTA CGCTGCCAAC GCAGGCAAAT CCGGCGGCGA ATTTTTCACC


 


601
CCGCAAAGCG TATCCAAGCT GATTGCGCGG CTGGCGGTGC ACGGGCAGGA


 


651
GAAAGTAAAC AAAATCTACG ACCCAGCTTG CGGCTCGGGC AGCCTGCTCT


 


701
TGCAGGCGAA AAAACAGTTT GACGAGCACA TCATCGAAGA AGGCTTCTTC


 


751
GGGCAGGAAA TCAACCACAC CACCTACAAC CTCGCCCGCA TGAATATGTT


 


801
TCTGCACAAC GTCAATTACA ACAAATTCCA CATCGAATTG GGCGACACAC


 


851
TGACCAATCC CAAACTCAAA GACAGCAAAC CCTTTGATGC CGTCGTTTCC


 


901
AATCCGCCCT ATTCCATCAA CTGGATAGGC AGCGGCGACC CCACCTTAAT


 


951
CAACGACGAC CGCTTTGCCC CTGCAGGCGT ACTCGCCCCG AAATCCAAAG


 


1001
CCGATTTTGC CTTCATTCTG CACGCACTGA ACTACCTTTC CGGCAGAGGC


 


1051
CGCGCCGCCA TCGTCTCATT CCCCGGCATT TTCTATCGCG GCGGCGCAGA


 


1101
GCAGAAAATC CGCCAATATC TGGTGGAGGG CAACTACGTG GAAACCGTCA


 


1151
TCGCCCTTGC GCCCAATCTC TTTTACGGCA CCGGCATCGC CGTCAATATA


 


1201
CTGGTTTTGT CCAAACACAA AGACAATACC GACATCCAAT TCATCGACGC


 


1251
AGGCGGCTTC TTTAAAAAAG AAACCAACAA CAACGTCTTA ACCGAAGAAC


 


1301
ACATTGCCGA AATCGTCAAA CTCTTCGCCG ATAAAGCCGA TGTGCCGCAT


 


1351
ATCGCCCAAA ACGCCGCCCA GCAAACCGTC AAAGACAACG GCTACAACCT


 


1401
CGCCGTCAGC AGCTATGTTG AACCCGAAGA CACCCGCGAA ATTATCGACA


 


1451
TCAAACAGCT TAACGCCGAA ATCAGCGAAA CCGTTGCCAA AATCGAACGG


 


1501
CTGCGGCGTG AAATTGACGA AGTGATTGCA GAGATTGAAG CATGA






This corresponds to the amino acid sequence <SEQ ID 1912; ORF 605.a>:










a605.pep




1
MMTEIQQRAQ LHRQIWKIAD EVRGAVDGWD FKQYVLGTLF YRFISENFTD


 


51
YMQAGDSSID YAAMPDSIIT PEIKDDAVKV KGYFIYPGQL FCNIAAEAHQ


 


101
NEELNTKLKE IFTAIESSAS GYPSEQDIKG LFDDFDTTSS RLGSTVADKN


 


151
KRLAAVLKGV AELDFGSFED HHIDLFGDAY EYLISNYAAN AGKSGGEFFT


 


201
PQSVSKLIAR LAVHGQEKVN KIYDPACGSG SLLLQAKKQF DEHIIEEGFF


 


251
GQEINHTTYN LARMNMFLHN VNYNKFHIEL GDTLTNPKLK DSKPFDAVVS


 


301
NPPYSINWIG SGDPTLINDD RFAPAGVLAP KSKADFAFIL HALNYLSGRG


 


351
RAAIVSFPGI FYRGGAEQKI RQYLVEGNYV ETVIALAPNL FYGTGIAVNI


 


401
LVLSKHKDNT DIQFIDAGGF FKKETNNNVL TEEHIAEIVK LFADKADVPH


 


451
IAQNAAQQTV KDNGYNLAVS SYVEPEDTRE IIDIKQLNAE ISETVAKIER


 


501
LRREIDEVIA EIEA*






m605/a605 98.1% identity in 514 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1913>:










g606.seq




1
ATGTCCAAAT TTATCGCCAA ACAATCGGTC GGTGCGGAAG TCATCGACAC


 


51
GCCGcgCACC GAAGAAGAAG CCTGGCTTCT GAACACTGTC GAAGCCCAAg


 


101
cgcGGCAATG GAATCTGAAA ACGCCAGAAG TCGCCATCTA CCACTCCCCC


 


151
GAACCCAATG CCTTTGCCAC GGGCGCATCG AGAAACAGCT CCCTGATCGC


 


201
CGTCAGCacc ggtttgctcg accaTAtgaC GCGCGACgaa gtggaagccg


 


251
tgTTGGCGCA CGAAATGGCG CACGTCGGCA ACGGCGACAT GGTTACGCTG


 


301
ACGCTGAtTC AAGGCGTGGT CAATACCTTT GTCGTGTTCC TGTCGCGCAT


 


351
TATTGCCAAC CTGATTGCCC GAAACAACGA CGGCAGCCAG TCCCAGGGAA


 


401
CTTATTTCCT AGTCAGCATG GTATTCCAAA TCCTGTTCGG CTTCCTTGCC


 


451
AGCCTGATTG TCATGTGGTT CAGCCGCCAA CGCGAATACC GCGCCGAcgc


 


501
gggCGcggCA AAACTGGTCG GCGCACCGAA AATGATTTCC GCCCTGCAAA


 


551
GGCTTAAAGG CAACCCGGTC GATTTGCCCG AAGAAATGAA CGCAATGGGC


 


601
ATCGCCGGAG ATACGCGCGA CTCCCTGCTC AGCACCCACC CTTCGCTGGA


 


651
CAACCGAATC GCCCGCCTCA AATCGCTTTA A






This corresponds to the amino acid sequence <SEQ ID 1914; ORF606.ng>:










g606.pep




1
MSKFIAKQSV GAEVIDTPRT EEEAWLLNTV EAQARQWNLK TPEVAIYHSP


 


51
EPNAFATGAS RNSSLIAVST GLLDHMTRDE VEAVLAHEMA HVGNGDMVTL


 


101
TLIQGVVNTF VVFLSRIIAN LIARNNDGSQ SQGTYFLVSM VFQILFGFLA


 


151
SLIVMWFSRQ REYRADAGAA KLVGAPKMIS ALQRLKGNPV DLPEEMNAMG


 


201
IAGDTRDSLL STHPSLDNRI ARLKSL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1915>:










m606.seq




1
ATGTCCAAAT TTATCGCCAA ACAATCGGTC GGCGCGGAAG TTATCGACAC


 


51
GCCGCGCACC GAAGAAGAAG CCTGGCTTTT GAACACTGTC GAAGCCCAAG


 


101
CGCGGCAATG GAACCTGAAA ACGCCCGAAG TCGCCATCTA CCACTCCCCC


 


151
GAACCCAATG CCTTTGCCAC GGGCGCATCG AGAAACAGCT CCCTGATCGC


 


201
CGTCAGCACC GGTTTGCTCG ACCATATGAC GCGTGACGAA GTGGAAGCCG


 


251
TATTGGCGCA CGAAATGGCA CACGTCGGCA ACGGCGATAT GGTTACGCTG


 


301
ACGCTGATTC AAGGCGTGGT CAATACCTTT GTCGTGTTCC TGTCGCGCAT


 


351
TATTGCCAAC CTGATTGCCC GAAACAACGA CGGCAGCCAG TCCCAGGGAA


 


401
CTTATTTCCT GGTCAGCATG GTATTCCAAA TCCTGTTCGG CTTCCTTGCC


 


451
AGCTTAATTG TCATGTGGTT CAGCCGACAA CGCGAATACC GCGCCGATGC


 


501
GGGCGCGGCA AAACTGGTCG GCGCGCCGAA AATGATTTCC GCCCTGCAAA


 


551
GGCTCAAAGG CAACCCGGTC GATTTGCCCG AAGAAATGAA CGCAATGGGC


 


601
ATCGCCGGAG ATACGCGCGA CTCCCTGCTC AGCACCCACC CTTCGCTGGA


 


651
CAACCGTATC GCCCGCCTCA AATCGCTTTA A






This corresponds to the amino acid sequence <SEQ ID 1916; ORF 606>:










m606.pep




1
MSKFIAKQSV GAEVIDTPRT EEEAWLLNTV EAQARQWNLK TPEVAIYHSP


 


51
EPNAFATGAS RNSSLIAVST GLLDHMTRDE VEAVLAHEMA HVGNGDMVTL


 


101
TLIQGVVNTF VVFLSRIIAN LIARNNDGSQ SQGTYFLVSM VFQILFGFLA


 


151
SLIVMWFSRQ REYRADAGAA KLVGAPKMIS ALQRLKGNPV DLPEEMNAMG


 


201
IAGDTRDSLL STHPSLDNRI ARLKSL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 606 shows 100.0% identity over a 225 aa overlap with a predicted ORF (ORF 606.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1917>:










a606.seq




1
ATGTCCAAAT TCATCGCCAA ACAATCGGTC GGCGCGGAAG TTATCGACAC


 


51
GCCGCGCACC GAAGAAGAAG CCTGGCTTTT GAACACTGTC GAAGCCCAAG


 


101
CGCGGCAATG GAACCTGAAA ACGCCCGAAG TCGCCATCTA CCACTCCCCC


 


151
GAACCCAATG CCTTTGCCAC GGGCGCATCG AGAAACAGCT CCCTGATCGC


 


201
CGTCAGCACC GGTTTGCTCG ACCATATGAC GCGTGACGAA GTGGAAGCCG


 


251
TATTGGCGCA CGAAATGGCA CACGTCGGCA ACGGCGATAT GGTTACGCTG


 


301
ACGCTGATTC AAGGCGTGGT CAATACCTTT GTCGTGTTCC TGTCGCGCAT


 


351
TATTGCCAAC CTGATTGCCC GAAACAACGA CGGCAGCCAG TCCCAGGGAA


 


401
CTTATTTCCT GGTCAGCATG GTATTCCAAA TCCTGTTCGG CTTCCTTGCC


 


451
AGCTTAATTG TCATGTGGTT CAGCCGACAA CGCGAATACC GCGCCGACGC


 


501
GGGCGCGGCA AAACTGGTCG GCGCGCCGAA AATGATTTCC GCCCTGCAAA


 


551
GGCTTAAAGG CAACCCGGTC GATTTGCCCG AAGAAATGAA CGCAATGGGC


 


601
ATCGCCGGAG ATACGCGCGA CTCCCTGCTC AGCACCCACC CTTCGCTGGA


 


651
CAACCGAATC GCCCGCCTCA AATCGCTTTA A






This corresponds to the amino acid sequence <SEQ ID 1918; ORF 606.a>:










a606.pep




1
MSKFIAKQSV GAEVIDTPRT EEEAWLLNTV EAQARQWNLK TPEVAIYHSP


 


51
EPNAFATGAS RNSSLIAVST GLLDHMTRDE VEAVLAHEMA HVGNGDMVTL


 


101
TLIQGVVNTF VVFLSRIIAN LIARNNDGSQ SQGTYFLVSM VFQILFGFLA


 


151
SLIVMWFSRQ REYRADAGAA KLVGAPKMIS ALQRLKGNPV DLPEEMNAMG


 


201
IAGDTRDSLL STHPSLDNRI ARLKSL*






m606/a606 100.0% identity in 226 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1919>:










g607.seq




1
ATGCTGCTCG accTcgaCCG CTTTTCCTtt tccGTCTTCC TGAAAGAAAT


 


51
CCGCCTGCTG ACCGCCCTTG CCCTGCCCAT GCTGTTGGCG CAGGTCGCGC


 


101
AGGTGGGCAT CGGTTTCGTC GATACCGTGA TGGCGGGCGG TGCGGGCAAG


 


151
GAAGATTTGG CGGCGGTGGC TTTGGGCAGC AGCGCGTTTG CCACGGTTTA


 


201
TATTACCTTT ATGGGCATTA TGGCGGCGCT GAACCCGATG ATTGCCCAGC


 


251
TTTACGGCGC GGGTAAAACC GgtgAAGCAG GCGAAACGGG GCGGCAGGGG


 


301
ATTTGGTTCG GGCTGATTTT GGGGATTTTC GGCATGATTT TGATGTGGGC


 


351
GGCGATTACG CCGTTCCGCA ACTGGCTGAC TTTGAGCGAT TATGTGGAAG


 


401
gcacAAtggc gcAGTATATG CTGTTCACCA GCTTGGCGAT GCCGGCGGCA


 


451
ATGGTACACC GCGCACTGCA CGCCTACGCT TCCAGCCTGA ACCGCCCGCG


 


501
CCTGATTATG TTGGTCAGCT TTGCGGCGTT TGTGTTGAAC GTGCCGCTGA


 


551
ACTATATTTT CGTTTACGGC AAATTCGGTA TGCCCGCTTT GGGTGGCGCA


 


601
GGTTGCGGCG TGGCGACAAT GGCGGTGTTT TGGTTCAGCG CGCTGGCATT


 


651
GTGGATTTAT ATCGCCAAGG AAAAATTCTT CCGCCCGTTC GGACTGACAG


 


701
CGAAATTCGg caaACCGGat tGGgcGGTGT TCAAACAGAT TtGGAAAATC


 


751
gGcgcgCCCA TCGGGCTGTC TTATTTTTTG GAAgccaGcg cGTTTTCGTT


 


801
TATCGTGTTT TTGATTGCGC CTttcggCGA GGATTATGTG GCGGCGCAGC


 


851
AGGTCGGCAT CAGTTTGTCG GGGATTCTCT ATATGATTCC GCAAAGCGTC


 


901
GGCTCGGCAG GGACGGTGCG CATCGGCTTT TCGCTTGGGC GGCGCGAATT


 


951
TTCGCGGGCG CGTTATATTT CAGGAGTGTC GCTGGTGTCG GGCTGGGTGC


 


1001
TCGCCGTGAT TACCGTGCTT TCCTTGGTAT TATTCCGTTC GCCGCTGGCA


 


1051
AGCATGTACA ACGATGaTCC GGCAGTTTTA AGCATCGCCT CCACCGTCCT


 


1101
GCTGTTCGCC GGCCTGTtcc aACCGGCAGA CTTCACCCAA TGTATCGCGT


 


1151
CCTATGCCCT GCGCGGCTAC AAAGTCACCA AGGTGCCGAT GTTCATCCAC


 


1201
GCCGCCGCCT TCTGGGGCTG CGGCCTGCTG CCGGGCTATC TGCTCGCCTA


 


1251
CCGTTTCGAT ATGGGCATTT ACGGCTTCTG GACGGCATTG ATTGCCTCGC


 


1301
TCACCATCGC AGCCGTCGCC TTGGTGTGGT GCTTGGAAAA ATACAGTATG


 


1351
GAGTTGGTCA AATCACACAA GGCCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 1920; ORF 607.ng>:










g607.pep




1
MLLDLDRFSF SVFLKEIRLL TALALPMLLA QVAQVGIGFV DTVMAGGAGK


 


51
EDLAAVALGS SAFATVYITF MGIMAALNPM IAQLYGAGKT GEAGETGRQG


 


101
IWFGLILGIF GMILMWAAIT PFRNWLTLSD YVEGTMAQYM LFTSLAMPAA


 


151
MVHRALHAYA SSLNRPRLIM LVSFAAFVLN VPLNYIFVYG KFGMPALGGA


 


201
GCGVATMAVF WFSALALWIY IAKEKFFRPF GLTAKFGKPD WAVFKQIWKI


 


251
GAPIGLSYFL EASAFSFIVF LIAPFGEDYV AAQQVGISLS GILYMIPQSV


 


301
GSAGTVRIGF SLGRREFSRA RYISGVSLVS GWVLAVITVL SLVLFRSPLA


 


351
SMYNDDPAVL SIASTVLLFA GLFQPADFTQ CIASYALRGY KVTKVPMFIH


 


401
AAAFWGCGLL PGYLLAYRFD MGIYGFWTAL IASLTIAAVA LVWCLEKYSM


 


451
ELVKSHKAV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1921>:










m607.seq




1
ATGCTGCTCG ACCTCAACCG CTTTTCCTTT CCCGTCTTCC TGAAAGAAGT


 


51
CCGCCTGCTG ACCACTCTTG CCCTGCCCAT GCTGTTGGCG CAGGTCGCGC


 


101
AGGTGGGCAT CGGTTTTGTC GATACTGTGA TGGCGGGCGG TGCGGGCAAG


 


151
GAAGACTTGG CGGCGGTGGC TTTGGGCAGC AGCGCGTTTG CCACGGTTTA


 


201
TATTACCTTT ATGGGCATTA TGGCGGCGCT GAACCCGATG ATTGCCCAGC


 


251
TTTACGGCGC GGGTAAAACC GACGAAGTGG GCGAAACGGG GCGGCAGGGG


 


301
ATTTGGTTCG GGCTGTTTTT GGGCGTGTTC GGCATGGTCT TGATGTGGGC


 


351
GGCGATTACG CCGTTCCGCA ACTGGCTGAC CTTGAGCGAT TATGTGGAAG


 


401
GCACGATGGC GCAGTATATG TTGTTCACCA GCTTGGCGAT GCCGGCGGCA


 


451
ATGGTACACC GCGCGCTGCA CGCCTACACT TCCAGCCTGA ACCGCCCGCG


 


501
CCTGATTATG TTGGTCAGCT TTGCGGCGTT TGTGTTGAAC GTGCCGCTGA


 


551
ACTATATTTT CGTTTACGGC AAATTCGGTA TGCCCGCTTT GGGCGGCGCA


 


601
GGCTGCGGAC TGGCGACGAT GGCGGTGTTT TGGTTCAGCG CGCTGGCATT


 


651
GTGGATTTAT ATCGCCAAGG AAAATTTCTT CCGCCCATTC GGACTGACGG


 


701
CGAAATTCGG CAAACCGGAT TGGGCGGTGT TCAAACAGAT TTGGAAAATC


 


751
GGCGCACCCA TCGGGCTGTC TTATTTTTTG GAAGCCAGCG CGTTTTCGTT


 


801
TATCGTGTTT TTGATTGCGC CTTTCGGCGA GGATTATGTG GCGGCGCAGC


 


851
AGGTCGGCAT CAGTTTGTCG GGGATTCTCT ATATGATTCC GCAAAGCGTC


 


901
GGCTCGGCGG GGACGGTGCG CATCGGCTTT TCGCTTGGGC GGCGCGAATT


 


951
TTCGCGGGCG CGTTATATTT CGGGCGTGTC ACTGGTGTTA GGATGGATGC


 


1001
TCGCCGTGAT TACCGTGCTT TCCTTGGTAT TATTCCGTTC GCCGCTGGTA


 


1051
AGTATGTACA ACAATGATCC GGCGGTTTTA AGCATCGCCG CCACCGTCTT


 


1101
ACTGTTCGCC GGCTTGTTCC AACCGGCAGA CTTCACCCAA TGTATCGCCT


 


1151
CCTACGCCTT GCGCGGCTAC AAAGTTACAA AGGTGCCGAT GTTCATCCAC


 


1201
GCCGCCGCCT TTTGGGGCTG CGGCCTGCTG CCGGGCTATC TGCTCGCCTA


 


1251
CCGTTTCAAT ATGGGCATTT ACGGCTTCTG GACGGCATTG ATTGCCTCGC


 


1301
TCACCATCGC CGCCATCGCC TTGGTGTGGT GCTTGGAATT GTGCAGTAGG


 


1351
GAGATGGTCA GATCGCATAA GGCCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 1922; ORF 607>:










m607.pep




1
MLLDLNRFSF PVFLKEVRLL TTLALPMLLA QVAQVGIGFV DTVMAGGAGK


 


51
EDLAAVALGS SAFATVYITF MGIMAALNPM IAQLYGAGKT DEVGETGRQG


 


101
IWFGLFLGVF GMVLMWAAIT PFRNWLTLSD YVEGTMAQYM LFTSLAMPAA


 


151
MVHRALHAYT SSLNRPRLIM LVSFAAFVLN VPLNYIFVYG KFGMPALGGA


 


201
GCGLATMAVF WFSALALWIY IAKENFFRPF GLTAKFGKPD WAVFKQIWKI


 


251
GAPIGLSYFL EASAFSFIVF LIAPFGEDYV AAQQVGISLS GILYMIPQSV


 


301
GSAGTVRIGF SLGRREFSRA RYISGVSLVL GWMLAVITVL SLVLFRSPLV


 


351
SMYNNDPAVL SIAATVLLFA GLFQPADFTQ CIASYALRGY KVTKVPMFIH


 


401
AAAFWGCGLL PGYLLAYRFN MGIYGFWTAL IASLTIAAIA LVWCLELCSR


 


451
EMVRSHKAV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 607 shows 94.8% identity over a 459 aa overlap with a predicted ORF (ORF 607.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1923>:










a607.seq




1
ATGCTGCTCG ACCTCAACCG CTTTTCCTTT TCCGTCTTCC TGAAAGAAGT


 


51
CCGCCTGCTG ACCGCTCTTG CCCTGCCCAT GCTGTTGGCG CAGGTCGCGC


 


101
AGGTGGGCAT CGGTTTTGTC GATACCGTGA TGGCGGGCGG TGCGGGCAAG


 


151
GAAGACTTGG CGGCGGTGGC TTTGGGCAGC AGCGCGTTTG CCACGGTTTA


 


201
TATTACCTTT ATGGGCATTA TGGCGGCGCT GAACCCGATG ATTGCCCAGC


 


251
TTTACGGCGC GGGTAAAACC GACGAAGTGG GCGAAACGGG ACGGCAGGGG


 


301
ATTTGGTTCG GGCTGTTTTT GGGCGTGTTC GGCATGGTCT TGATGTGGGC


 


351
GGCGATTACG CCGTTCCGCA ACTGGCTGAC CTTGAGCGAT TATGTGGAAG


 


401
GCACAATGGC GCAGTATATG CTGTTCACCA GCTTGGCGAT GCCGGCGGCA


 


451
ATGGTACACC GCGCACTGCA CGCCTACGCC TCCAGCCTGA ACCGCCCGCG


 


501
CCTGATTATG TTGGTCAGCT TTGCGGCGTT TGTGTTGAAC GTGCCGCTGA


 


551
ACTATATTTT CGTTTACGGC AAATTCGGTA TGCCCGCTTT GGGCGGCGCA


 


601
GGCTGCGGAC TGGCGACGAT GGCGGTGTTT TGGTTCAGCG CGCTGGCATT


 


651
GTGGATTTAT ATCGCCAAGG AAAATTTCTT CCGCCCATTC GGACTGACGG


 


701
CGAAATTCGG CAAACCGGAT TGGGCGGTGT TCAAACAGAT TTGGAAAATC


 


751
GGCGCACCCA TCGGGCTGTC TTATTTTTTG GAAGCCAGCG CGTTTTCGTT


 


801
TATCGTGTTT TTGATTGCGC CTTTCGGCGA GGATTATGTG GCGGCGCAGC


 


851
AGGTCGGCAT CAGTTTGTCG GGGATTCTCT ATATGATTCC GCAAAGCGTC


 


901
GGCTCGGCGG GGACGGTGCG CATCGGCTTT TCGCTTGGGC GGCGCGAATT


 


951
TTCGCGGGCG CGTTATATTT CGGGCGTGTC ACTGGTGTCA GGATGGATGC


 


1001
TCGCCGTGAT TACCGTGCTT TCCTTGGTAT TATTCCGTTC GCCGCTGGTA


 


1051
AGTATGTACA ACAATGATCC GGCGGTTTTA AGCATCGCCG CCACCGTCTT


 


1101
ACTGTTCGCC GGCTTGTTCC AACCGGCAGA CTTCACCCAA TGTATCGCCT


 


1151
CCTACGCCTT GCGCGGCTAC AAAGTTACAA AGGTGCCGAT GTTCATCCAC


 


1201
GCCGCCGCCT TTTGGGGCTG CGGTCTGCTG CCGGGCTACC TGCTCGCCTA


 


1251
CCGTTTCGAT ATGGGCATTT ACGGCTTCTG GACGGCATTG ATTGCCTCGC


 


1301
TCACCATCGC CGCCATCGCC TTGGTGTGGT GCTTGGAATT GTGCAGTAGG


 


1351
GAGATGGTCA GATCGCATAA GGCTGTCTGA






This corresponds to the amino acid sequence <SEQ ID 1924; ORF 607.a>:










a607.pep




1
MLLDLNRFSF SVFLKEVRLL TALALPMLLA QVAQVGIGFV DTVMAGGAGK


 


51
EDLAAVALGS SAFATVYITF MGIMAALNPM IAQLYGAGKT DEVGETGRQG


 


101
IWFGLFLGVF GMVLMWAAIT PFRNWLTLSD YVEGTMAQYM LFTSLAMPAA


 


151
MVHRALHAYA SSLNRPRLIM LVSFAAFVLN VPLNYIFVYG KFGMPALGGA


 


201
GCGLATMAVF WFSALALWIY IAKENFFRPF GLTAKFGKPD WAVFKQIWKI


 


251
GAPIGLSYFL EASAFSFIVF LIAPFGEDYV AAQQVGISLS GILYMIPQSV


 


301
GSAGTVRIGF SLGRREFSRA RYISGVSLVS GWMLAVITVL SLVLFRSPLV


 


351
SMYNNDPAVL SIAATVLLFA GLFQPADFTQ CIASYALRGY KVTKVPMFIH


 


401
AAAFWGCGLL PGYLLAYRFD MGIYGFWTAL IASLTIAAIA LVWCLELCSR


 


451
EMVRSHKAV*






m607/a607 98.9% identity in 459 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1925>:










g608.seq




1
ATGTCCGCCC TCCTCCCCAT CATCAACCGC CTGATTCTGC AAAGCCCGGA


 


51
CAGCCGCTCG GAACTTACCT CCTTTGCAGG CAAAACACTG ACCCTGAACA


 


101
TTGCCGGGCT GAAACTGGCG GGACGCATCA CAGAAGACGG TTTGCTCTCG


 


151
GCGGGAAACG GCTTTGCAGA CACCGAAATT ACCTTCCGCA ACAGCGCGAT


 


201
ACGGAAAATC CTCCAAGGCG GCGAACCCGG GGCTGGCGAC ATCAGGCTCG


 


251
AAGGCGACCT CATCCTCGGC ATcGCGGTAC TGTCCCTGCT CGGCAGCCTG


 


301
CGTTCCCGCG CATCGGacgA ATTGGCACGG ATTTTCGGCA CGCAGGCAGg


 


351
catcggcagc CGTGCCACCG ACATCGGACA CGGCaTCaaa cAAATCGGCA


 


401
GGAACATCGC CGAACAAATC GGCGGATTTT CCCGCGAACC CGAGTCcgCa


 


451
aacaccggca acgaagccct tgccgactgc ctCGACGAAA TAAGCAGACT


 


501
GCGCGACGGC GTGGAACGCC TCAACGAACG CCTCGACAGG CTCGAACGCG


 


551
ACATTTGGAT AGACTAA






This corresponds to the amino acid sequence <SEQ ID 1926; ORF 608.ng>:










g608.pep




1
MSALLPIINR LILQSPDSRS ELTSFAGKTL TLNIAGLKLA GRITEDGLLS


 


51
AGNGFADTEI TFRNSAIRKI LQGGEPGAGD IRLEGDLILG IAVLSLLGSL


 


101
RSRASDELAR IFGTQAGIGS RATDIGHGIK QIGRNIAEQI GGFSREPESA


 


151
NTGNEALADC LDEISRLRDG VERLNERLDR LERDIWID*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1927>:










m608.seq




1
ATGTCCGCCC TCCTCCCCAT CATCAACCGC CTGATTCTGC AAAGCCCGGA


 


51
CAGCCGCTCG GAACTTGCCG CCTTTGCAGG CAAAACACTG ACCCTGAACA


 


101
TTGCCGGGCT GAAACTGGCG GGACGCATCA CGGAAGACGG TTTGCTCTCG


 


151
GCGGGAAACG GCTTTGCAGA CACCGAAATT ACCTTCCGCA ACAGCGCGGT


 


201
ACAGAAAATC CTCCAAGGAG GCGAACCCGG GGCGGGCGAC ATCGGGCTCG


 


251
AAGGCGACCT CATCCTCGGC ATCGCGGTAC TGTCCCTGCT CGGCAGCCTG


 


301
CGTTCCCGCG CATCGGACGA ATTGGCACGG ATTTTCGGCA CGCAGGCAGA


 


351
CATCGGCAGC CGTGCCGCCG ACATCGGACA CGGCATCAAA CAAATCGGCA


 


401
GGAACATCGC CGAACAAATC GGCGGATTTT CCCGCGAATC CGAGTCCGCA


 


451
AACATCGGCA ACGAAGCCCT TGCCGACTGC CTCGACGAAA TAAGCAGACT


 


501
GCGCGACGGC GTGGAACGCC TCAACGAACG CCTCGACCGG CTCGAACGCG


 


551
ACATTTGGAT AGACTAA






This corresponds to the amino acid sequence <SEQ ID 1928; ORF 608>:










m608.pep




1
MSALLPIINR LILQSPDSRS ELAAFAGKTL TLNIAGLKLA GRITEDGLLS


 


51
AGNGFADTEI TFRNSAVQKI LQGGEPGAGD IGLEGDLILG IAVLSLLGSL


 


101
RSRASDELAR IFGTQADIGS RAADIGHGIK QIGRNIAEQI GGFSRESESA


 


151
NIGNEALADC LDEISRLRDG VERLNERLDR LERDIWID*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 608 shows 95.2% identity over a 188 aa overlap with a predicted ORF (ORF 608.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1929>:










a608.seq




1
ATGTCCGCCC TCCTCCCCAT CATCAACCGC CTGATTCTGC AAAGCCCGGA


 


51
CAGCCGCTCG GAACTTGCCG CCTTCGCAGG CAAAACACTG ACCCTGAACA


 


101
TTGCCGGGTT GAAACTGGCG GGACGCATCA CGGAAGACGG TTTGCTCTCG


 


151
GCGGGAAACG GCTTTGCAGA CACCGAAATC ACCTTCCGCA ACAGCGCGGT


 


201
ACAGAAAATC CTCCAAGGCG GCGAACCCGG GGCGGGCGAC ATCGGGCTCG


 


251
AAGGCGACCT CATCCTCGGC ATCGCGGTAC TGTCCCTGCT CGGCAGCCTG


 


301
CGTTCCCGCG CATCGGACGA ATTGGCACGG ATTTTCGGCA CGCAGGCAGA


 


351
CATCGGCAGC CGTGCCGCCG ACATCGGACA CGGCATCAAA CAAATCGGCA


 


401
GGAACATCGC CGAACAAATC GGCAGATTTT CCCGCGAACC CGAGTCCGCA


 


451
AACATCGGCA ACGAAGCCCT TGCCGACTGC CTCGACGAAA TAAGCAGACT


 


501
GCGCGACGGC GTGGAACGCC TCAACGAACG CCTCGACCGG CTCGAACGCG


 


551
ACATTTGGAT AGACTAA






This corresponds to the amino acid sequence <SEQ ID 1930; ORF 608.a>:










a608.pep




1
MSALLPIINR LILQSPDSRS ELAAFAGKTL TLNIAGLKLA GRITEDGLLS


 


51
AGNGFADTEI TFRNSAVQKI LQGGEPGAGD IGLEGDLILG IAVLSLLGSL


 


101
RSRASDELAR IFGTQADIGS RAADIGHGIK QIGRNIAEQI GRFSREPESA


 


151
NIGNEALADC LDEISRLRDG VERLNERLDR LERDIWID*






m608/a608 98.9% identity in 188 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1931>:










g609.seq




1
ATGGTTGTGG ATAGACTCGA AATTCTCGCT CTCGACGACG AAACTCTTGA


 


51
TGCGTTTGTC GGCAATCAGC GAAGTAGCGA CATCGCGCAC CATATCTTCC


 


101
ACGAATTTCG GGTTTTCGTA GGCCTTTTCG GTAACGTATT TTTCATCGGG


 


151
GCGTTTGAGC AGGCCGTAGA GTTGGCAGCT CGCCTGCGTT TCCACATAAT


 


201
CGATAACTTC CTCGATACCG ACTTCGGCAT CGGAAGTCAG GCTGACGGTA


 


251
ACGTGCGAAC GCTGATTATG CGCGCCATAT TGGGAAATTT CTTTGGAACA


 


301
CGGGCAAAGC GAGGTTACGG GAATCATGAC CTTCATACTG TGGCCGTATG


 


351
CCCCGTCTTT CATTTCACCC GTGAGGCTGA CATCATAATC CAGtaa






This corresponds to the amino acid sequence <SEQ ID 1932; ORF 609.ng>:










g609.pep




1
MVVDRLEILA LDDETLDAFV GNQRSSDIAH HIFHEFRVFV GLFGNVFFIG


 


51
AFEQAVELAA RLRFHIIDNF LDTDFGIGSQ ADGNVRTLIM RAILGNFFGT


 


101
RAKRGYGNHD LHTVAVCPVF HFTREADIII Q*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1933>:










m609.seq




1
ATGGTTGTGG ATAGACTCGA AATTCTCGCT CTCGACGACG AAACTCTTGA


 


51
TGCGTTTGTC GGCAATCAGC GAAGTAGCGA CATCGCGCAC CATATCTTCC


 


101
ACGAATTTCG GGTTTTCGTA GGCTTTTTCG GTAACGTATT TTTCATCGGG


 


151
GCGTTTGAGC AGGCCGTAGA GTTGGCAGCT CGCCTGCGCC TCCACATAAT


 


201
CGATGACTTC CTCGATACCG ACTTCGGCAT CGGCAGTCAG GCTGACGGTA


 


251
ACGTGCGAAC GCTGGTTGTG CGCGCCGTAT TGGGAAATTT CTTTGGAACA


 


301
CGGGCAAAGC GAGGTTACGG GAATCATGAC CTTCATACTG TGGCCGTATG


 


351
CCCCGTCTTT GATTTCGCCC GTGAGACAGA CATCATAATC CAGTAA






This corresponds to the amino acid sequence <SEQ ID 1934; ORF 609>:










m609.pep




1
MVVDRLEILA LDDETLDAFV GNQRSSDIAH HIFHEFRVFV GFFGNVFFIG


 


51
AFEQAVELAA RLRLHIIDDF LDTDFGIGSQ ADGNVRTLVV RAVLGNFFGT


 


101
RAKRGYGNHD LHTVAVCPVF DFARETDIII Q*






m609/g609 93.1% identity in 131 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1935>:










a609.seq




1
ATGGTTGTGG ATAGACTCGA AATTCTCGCT CTCGACGACG AAACTCTTGA


 


51
TGCGTTTGTC GGCAATCAGC GAAGTAGCGA CATCGCGCAC CATATCTTCC


 


101
ACGAATTTCG GGTTTTCGTA GGCTTTTTCG GTAACGTATT TTTCATCGGG


 


151
GCGTTTGAGC AGGCCGTAGA GTTGGCAGCT CGCCTGCGCC TCCACATAAT


 


201
CGATGACTTC CTCGATACCG ACTTCGGCAT CGGCAGTCAG GCTGACGGTA


 


251
ACGTGCGAAC GCTGGTTGTG CGCGCCATAT TGGGAAATTT CTTTGGAACA


 


301
CGGGCAAAGC GAGGTTACGG GAATCATGAC CTTCATACTG TGGCCGTATG


 


351
CACCGTCTTT CATTTCGCCC GTGAGGCTGA CATCATAATC CAGTAA






This corresponds to the amino acid sequence <SEQ ID 1936; ORF 609.a>:










a609.pep




1
MVVDRLEILA LDDETLDAFV GNQRSSDIAH HIFHEFRVFV GFFGNVFFIG


 


51
AFEQAVELAA RLRLHIIDDF LDTDFGIGSQ ADGNVRTLVV RAILGNFFGT


 


101
RAKRGYGNHD LHTVAVCTVF HFAREADIII Q*






m609/a609 96.9% identity in 131 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1937>:










g610.seq




1
ATGATTGGAG GGCTTATGCA ATTTCCTTAC CGCAATGTTC CGGCTTCGCG


 


51
TATGCGCCGT ATGCGCAGGG ATGATTTTTC ACGCCGCCTG ATGCGCGAGC


 


101
ATATGCTGAC CGCCGATGAT TTGATTTATC CGGTGTTCGT ATTGGAGGGG


 


151
GCGGCGCGCG AGGAGGATGT GCCTTCTATG CCGGGCGTGA AGCGTCAGAG


 


201
TTTGGACAGG CTGCTGTTTA CGGCGGAAGA GGCGGTGAAG CTCGGTATTC


 


251
CGATGTTGGC ACTCTTTCCC GTGGTTACGG CAAACAAAAC CGGGCGTGCG


 


301
CAGGAGGCGT ACAATCCCGA AGGACTCGTG CCGTCAACTG tccgagccTT


 


351
GCGCGAGAGG TttcCcgaac tggggattat gacggatgtc gcgctcgAtc


 


401
cttatacggt gcacGGTCAG GACGGACTGA CGGACgaaaa cggttaCGTG


 


451
ATGAatgATg aaaCCGTAGA AGTCTTGGTG AAACAGGCTT TATGTCATGC


 


501
AGAGGCGGGC ACGCAGGTCG TTGCTCCTTC CGATATGATG GACGGGCGTA


 


551
TCGGCGCCAT CCGCGAGGCT TTGGAGGATG CCGGACATAT CCATACGCGG


 


601
ATTATGGCAT ATTCCGCCAA ATATGCTTCT GCATTCTACG GCCCTTTCCG


 


651
TGATGCGGTA GGCAGTTCGG GCAATTTGGG AAAGGCAGAT AAAAAGACCT


 


701
ATCAGATGGA TCCTGCAAAT ACCGATGAGG CGCTGCATGA AGTGGCGCTC


 


751
GATATTCAGG AAGGTGCGGA TATGGTGATG GTGAAGCCCG GTTTGCCGTA


 


801
TTTGGACGTT GTCCGCCGCG TGAAGGACGA GTTCGGCGTA CCGACTTATG


 


851
CCTATCAGGT TTCGGGCGAA TATGCGATGT TGCAGGCGGC GGTTGCCAAC


 


901
GGCTGGCTGG ACGGCGGCAA AGTGGTTTTG GAAAGCCTGC TGGCATTCAA


 


951
ACGTGCGGGT GCGGACGGGA TTTTGACCTA TTACGCCATT GAGGCGGCAA


 


1001
AGATGCTGAA GCGTTGA






This corresponds to the amino acid sequence <SEQ ID 1938; ORF 610.ng>:










g610.pep




1
MIGGLMQFPY RNVPASRMRR MRRDDFSRRL MREHMLTADD LIYPVFVLEG


 


51
AAREEDVPSM PGVKRQSLDR LLFTAEEAVK LGIPMLALFP VVTANKTGRA


 


101
QEAYNPEGLV PSTVRALRER FPELGIMTDV ALDPYTVHGQ DGLTDENGYV


 


151
MNDETVEVLV KQALCHAEAG TQVVAPSDMM DGRIGAIREA LEDAGHIHTR


 


201
IMAYSAKYAS AFYGPFRDAV GSSGNLGKAD KKTYQMDPAN TDEALHEVAL


 


251
DIQEGADMVM VKPGLPYLDV VRRVKDEFGV PTYAYQVSGE YAMLQAAVAN


 


301
GWLDGGKVVL ESLLAFKRAG ADGILTYYAI EAAKMLKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1939>:










m610.seq




1
ATGATTGGAG GGCTTATGCA GTTTCCTTAC CGCAATGTTC CGGCTTCGCG


 


51
TATGCGCCGT ATGCGCAGGG ACGATTTTTC ACGCCGCCTG ATGCGCGAAC


 


101
ACACGCTGAC CGCCGATGAT TTGATTTATC CGGTGTTCGT ATTGGAGGGG


 


151
TCGGCGCGCG AGGAGGATGT GCCTTCTATG CCGGGTGTGA AGCGTCAAAG


 


201
TTTGGACAGG CTGCTGTTTA CGGCGGAAGA GGCGGTAAAG CTCGGTATTC


 


251
CGATGTTGGC ACTGTTCCCC GTGGTTACGG CAAACAAAAC CGAGCGTGCG


 


301
CAGGAGGCGT ACAATCCCGA AGGACTCGTG CCGTCAACTG TCCGCGCCTT


 


351
GCGCGAGAGG TTTCCCGAAC TGGGCATTAT GACGGATGTC GCGCTCGATC


 


401
CTTATACGGT TCACGGTCAG GACGGGCTGA CGGACGAAAA CGGTTATGTG


 


451
ATGAACGATG AAACCGTAGA GGTTTTGGTC AAGCAGGCTT TGTGCCACGC


 


501
TGAAGCGGGC GCGCAGGTGG TTGCCCCTTC CGATATGATG GACGGGCGTA


 


551
TCGGTGCGAT TCGCGAGGCG TTGGAGGATG CCGGGCATAT CCATACGCGG


 


601
ATTATGGCGT ATTCCGCCAA ATATGCTTCT GCATTTTACG GCCCTTTCCG


 


651
TGATGCGGTA GGCAGTTCGG GCAATTTGGG CAAGGCAGAT AAAAAGACCT


 


701
ACCAGATGGA TCCGGCAAAT ACCGATGAGG CGTTGCACGA AGTGGCGTTG


 


751
GACATTCAGG AAGGTGCGGA TATGGTAATG GTCAAGCCCG GTTTGCCGTA


 


801
TTTGGACGTT GTCCGCCGCG TAAAGGACGA GTTCGGTGTG CCGACTTATG


 


851
CCTATCAGGT TTCGGGAGAA TACGCGATGT TGCAGGCAGC GATTGCCAAC


 


901
GGCTGGCTGG ACGGCGGCAA AGTGGTTTTG GAAAGCCTGC TGGCATTCAA


 


951
ACGTGCGGGT GCGGACGGGA TTTTGACCTA TTACGCTATT GAGGCGGCAA


 


1001
AGATGTTGAA GCGTTGA






This corresponds to the amino acid sequence <SEQ ID 1940; ORF 610>:










m610.pep




1
MIGGLMQFPY RNVPASRMRR MRRDDFSRRL MREHTLTADD LIYPVFVLEG


 


51
SAREEDVPSM PGVKRQSLDR LLFTAEEAVK LGIPMLALFP VVTANKTERA


 


101
QEAYNPEGLV PSTVRALRER FPELGIMTDV ALDPYTVHGQ DGLTDENGYV


 


151
MNDETVEVLV KQALCHAEAG AQVVAPSDMM DGRIGAIREA LEDAGHIHTR


 


201
IMAYSAKYAS AFYGPFRDAV GSSGNLGKAD KKTYQMDPAN TDEALHEVAL


 


251
DIQEGADMVM VKPGLPYLDV VRRVKDEFGV PTYAYQVSGE YAMLQAAIAN


 


301
GWLDGGKVVL ESLLAFKRAG ADGILTYYAI EAAKMLKR*






m610/g610 98.5% identity in 338 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1941>:










a610.seq




1
ATGATTGGAG GGCTTATGCA GTTTCCTTAC CGCAATGTTT CGGCTTCGCG


 


51
TATGCGCCGT ATGCGCAGGG ACGATTTTTC ACGCCGCCTG ATGCGCGAGC


 


101
ATACGCTGAC TGCCGATGAT TTGATTTATC CGGTGTTCGT ATTGGAGGGG


 


151
TCGGCGCGCG AGGAGGATGT GCCTTCTATG CCGGGCGTGA AGCGTCAGAG


 


201
TTTGGACAGG CTGCTGTTTA CGGCGGAAGA GGCGGTAAAG CTCGGTATTC


 


251
CGATGTTGGC ACTGTTCCCC GTGGTTACGG CAAACAAAAC CGAGCGTGCG


 


301
CAGGAGGCGT ACAATCCCGA AGGACTCGTG CCGTCAACTG TCCGCGCCTT


 


351
GCGCGAGAGG TTTCCCGAAC TGGGCATTAT GACGGATGTC GCGCTCGATC


 


401
CTTATACGGT GCACGGTCAG GACGGGCTGA CGGACGAAAA CGGTTATGTG


 


451
ATGAACGATG AAACCGTAGA GGTTTTGGTC AAGCAGGCTT TGTGTCATGC


 


501
AGAGGCAGGC GCACAGGTCG TTGCTCCTTC CGATATGATG GATGGGCGTA


 


551
TCGGTGCGAT TCGCGAGGCG TTGGAGGATG CCGGGCATAT CCATACGCGG


 


601
ATTATGGCGT ATTCCGCCAA ATATGCTTCT GCATTTTACG GCCCTTTCCG


 


651
TGATGCGGTA GGCAGTTCGG GCAATTTGGG CAAGGCAGAT AAAAAGACCT


 


701
ACCAGATGGA TCCGGCAAAT ACCGATGAGG CGTTGCACGA AGTGGCGTTG


 


751
GACATTCAGG AAGGTGCGGA TATGGTGATG GTCAAGCCCG GTTTGCCGTA


 


801
TTTGGACGTT GTCCGCCGCG TGAAGGACGA GTTCGGCGTG CCGACTTATG


 


851
CCTATCAGGT TTCGGGAGAA TACGCGATGC TGCAGGCGGC GGTTGCCAAC


 


901
GGCTGGCTGG ACGGCGGCAA AGTGGTTTTG GAAAGCCTGC TGGCATTCAA


 


951
ACGTGCGGGT GCGGATGGGA TTTTGACCTA TTACGCCATT GAGGCGGCAA


 


1001
AGATGCTGAA GCGTTGA






This corresponds to the amino acid sequence <SEQ ID 1942; ORF 610.a>:










a610.pep




1
MIGGLMQFPY RNVSASRMRR MRRDDFSRRL MREHTLTADD LIYPVFVLEG


 


51
SAREEDVPSM PGVKRQSLDR LLFTAEEAVK LGIPMLALFP VVTANKTERA


 


101
QEAYNPEGLV PSTVRALRER FPELGIMTDV ALDPYTVHGQ DGLTDENGYV


 


151
MNDETVEVLV KQALCHAEAG AQVVAPSDMM DGRIGAIREA LEDAGHIHTR


 


201
IMAYSAKYAS AFYGPFRDAV GSSGNLGKAD KKTYQMDPAN TDEALHEVAL


 


251
DIQEGADMVM VKPGLPYLDV VRRVKDEFGV PTYAYQVSGE YAMLQAAVAN


 


301
GWLDGGKVVL ESLLAFKRAG ADGILTYYAI EAAKMLKR*






m610/a610 99.4% identity in 338 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1943>:










g611.seq




1
ATGCCGTCTG AAAACGGGAT GGGAAAACGG CAGCTTGCGG GCTGCCGTTT


 


51
GTTCGGGAAG TTAAGCCTTG TTTTCAGGCT GCTGCCCGGA CTCTGTCGAG


 


101
GCGGTGTCTG CCGGGGCAGG TGCTTCGGTT TTTTCCCGAG TCGGAGCGTG


 


151
CGGCGCGTTA TCTTCCGCCG CGTCCGCATT Ctcgcgcagg ttgtGGCtgt


 


201
tatcctTGGG CGGGCTGggt tgtttgcccg ccataaTTtc cagtacctgA


 


251
TcgcgGTCta tggtttcCCa ttCcatcagg gctttgcaca TCGTTTCCAT


 


301
cttgTCGCGG TTTTcatcga ggaTTTTGTA ggcaacCTGA TACTgctcgt


 


351
ccaaaAtccg Gcggatttcc gcgtcgAtgt cctgctgggt tTTCTCGGAA


 


401
ATGTTTTGCG AACGGgttac gctGCGCCCC AAGAAGACTT CGCCTTCGTT


 


451
TTCCGCATAA ACCATCACGC CCATTTTGtc gCTCAtgcCG TAGCGCGTTA


 


501
CCATTTCGCG TGCCATTTGG GTTGCGCGTT CAAAGTCGTT TGA






This corresponds to the amino acid sequence <SEQ ID 1944; ORF 611.ng>:










g611.pep




1
MPSENGMGKR QLAGCRLFGK LSLVFRLLPG LCRGGVCRGR CFGFFPSRSV


 


51
RRVIFRRVRI LAQVVAVILG RAGLFARHNF QYLIAVYGFP FHQGFAHRFH


 


101
LVAVFIEDFV GNLILLVQNP ADFRVDVLLG FLGNVLRTGY AAPQEDFAFV


 


151
FRINHHAHFV AHAVARYHFA CHLGCAFKVV *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1945>:










m611.seq




1
ATGCCGTCTG AAAACGGGAT GGGAAAACGG CAGCTTGCGG GCTGCCGTTT


 


51
GTTCGGGAAG TTAAGCCTTG TTTTCAGGCT GCTGCTCGGA CTCTGTCGAA


 


101
GCGGTGTCTG CCGGGGCAGG TGCTTCGGTT TCTTCCCGAG TCGGAGCGTG


 


151
CGGCGCGTTA TCTTCCGCCG CGTCCGCATT CTCGCGCAGG TTGTGGCTGT


 


201
AATCTTTGGG CGGGCTGGGT TGTTTGCCCG CCATGATTTC CAGTACCTGA


 


251
TCGCGGTCGA TGGTTTCCCA TTCCATCAGG GCTTTGCACA TCGTTTCCAT


 


301
CTTGTCGCGG TTTTCATCGA GGATTTTGTA GGCAACCTGA TATTGCTCGT


 


351
CCAAAATCCG GCGGATTTCC GCGTCGATGT CCTGCTGGGT TTTCTCGGAA


 


401
ATGTTTTGCG AACGGGTTAC GCTGCGTCCC AAGAAGACTT CGCCTTCGTT


 


451
TTCCGCATAA ACCATCACGC CCATTTTGTC GCTCATGCCG TAGCGCGTTA


 


501
CCATTTCGCG CGCCATTTGG GTTGCGCGTT CAAAGTCGTT TGA






This corresponds to the amino acid sequence <SEQ ID 1946; ORF 611>:










m611.pep




1
MPSENGMGKR QLAGCRLFGK LSLVFRLLLG LCRSGVCRGR CFGFFPSRSV


 


51
RRVIFRRVRI LAQVVAVIFG RAGLFARHDF QYLIAVDGFP FHQGFAHRFH


 


101
LVAVFIEDFV GNLILLVQNP ADFRVDVLLG FLGNVLRTGY AASQEDFAFV


 


151
FRINHHAHFV AHAVARYHFA RHLGCAFKVV *






m611/g611 96.1% identity in 180 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1947>:










a611.seq




1
ATGCCGTCTG AAAACAGGAT GGGAAAACGG CAGCTTGCGG GCTGCCGTTT


 


51
GTTCGGGAAG TTAAGCCTTG TTTTCAGGCT GCTGCTCGGA CTCTGTCGAA


 


101
GCGGTGTCTG CCGGGGCAGG TGCTTCGGTT TCTTCCCGAG TCGGAGCGTG


 


151
CGGCGCGTTA TCTTCCGCCG CGTCCGCATT CTCGCGCAGG TTGTGGCTGT


 


201
AATCTTTGGG CGGGCTGGGT TGTTTGCCCG CCATGATTTC CAGTACCTGA


 


251
TCGCGGTCGA TGGTTTCCCA TTCCATCAGG GCTTTGCACA TCGTTTCCAT


 


301
CTTGTCGCGG TTTTCATCGA GGATTTTGTA GGCAACCTGA TACTGCTCGT


 


351
CCAAAATCCG GCGGATTTCC GCATCGATGT CCTGCTGGGT TTTCTCGGAA


 


401
ATGTTTTGCG AACGGGTTAC GCTGCGTCCC AAGAAGACTT CGCCTTCGTT


 


451
TTCCGCATAA ACCATCACGC CCATTTTGTC GCTCATGCCG TAGCGCGTTA


 


501
CCATTTCGCG CGCCATTTGG GTTGCGCGTT CAAAGTCGTT TGA






This corresponds to the amino acid sequence <SEQ ID 1948; ORF 611.a>:










a611.pep




1
MPSENRMGKR QLAGCRLFGK LSLVFRLLLG LCRSGVCRGR CFGFFPSRSV


 


51
RRVIFRRVRI LAQVVAVIFG RAGLFARHDF QYLIAVDGFP FHQGFAHRFH


 


101
LVAVFIEDFV GNLILLVQNP ADFRIDVLLG FLGNVLRTGY AASQEDFAFV


 


151
FRINHHAHFV AHAVARYHFA RHLGCAFKVV *






m611/a611 98.9% identity in 180 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1949>:










g612.seq




1
ATGGgcttcg gcggcaatat tgcAAAAAAG CTGGCcggGg taGATGAAAT


 


51
AGCCTttgac tttgacggcA TCGTCTTTGA TTTCGGGCGT GATGATGCTG


 


101
TCCGGCataG CGGCGTAATC AATGCTGCTG TCGCCGGCCT GCATATAGTC


 


151
GGTGAAGTTT TCGCTGATAA AGCGGTAGAA AAGTGTGCCG AGAACGTATT


 


201
GTTTAAAGTC CCAGCCATCC ACCGCGCCGC GTACTTCGTC GGCGATTTTC


 


251
CAAATTTGGC GGTGCAGTTG GGCGCGTTGT TGCATTTCGG TCATCATCGA


 


301
AATCCATATA TAAAGTTAAA CAAATCAAAA TCGCCTGATA TTTTCAGACG


 


351
ATTTTTTTAC GGGCATTCAA ATTAA






This corresponds to the amino acid sequence <SEQ ID 1950; ORF 612.ng>:










g612.pep




1
MGFGGNIAKK LAGVDEIAFD FDGIVFDFGR DDAVRHSGVI NAAVAGLHIV


 


51
GEVFADKAVE KCAENVLFKV PAIHRAAYFV GDFPNLAVQL GALLHFGHHR


 


101
NPYIKLNKSK SPDIFRRFFY GHSN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1951>:










m612.seq




1
ATGGGCTTCG GCGGCAATAT TGCAAAAAAG CTGGCCGGGG TAGATGAAAT


 


51
AGCCTTTAAC TTTGACGGCA TCGTCTTTGA TTTCGGGCGT GATGATGCTG


 


101
TCCGGCATAG CGGCGTAATC AATACTGCTG TCGCCTGCCT GCATATAGTC


 


151
GGTGAAGTTT TCGCTGATAA AGCGGTAGAA AAGTGTGCCG AGAACGTATT


 


201
GTTTAAAGTC CCAGCCATCC ACCGCGCCGC GTACTTCGTC GGCAATTTTC


 


251
CAAATTTGGC GGTGCAGTTG GGCGCGTTGT TGCATTTCGG TCATCATCGA


 


301
AATCCATATA .AAAGTTAAA CAAATCAAAA TCGCCTGATA TTTTCAGACG


 


351
ATTTTTTTAC GGGCATTCAA ATTAA






This corresponds to the amino acid sequence <SEQ ID 1952; ORF 612>:










m612.pep




1
MGFGGNIAKK LAGVDEIAFN FDGIVFDFGR DDAVRHSGVI NTAVACLHIV


 


51
GEVFADKAVE KCAENVLFKV PAIHRAAYFV GNFPNLAVQL GALLHFGHHR


 


101
NPYXKLNKSK SPDIFRRFFY GHSN*






m612/g612 96.0% identity in 124 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1953>:










a612.seq




1
ATGGGCTTCG GCGGCAATAT TGCAAAAAAG CTGGCCGGGG TAGATGAAAT


 


51
AGCCTTTGAC TTTGACGGCA TCGTCTTTGA TTTCGGGCGT GATGATGCTG


 


101
TCCGGCATAG CGGCGTAATC AATACTGCTG TCGCCTGCCT GCATATAGTC


 


151
GGTAAAGTTT TCGCTGATAA AGCGGTAGAA AAGTGTGCCG AGAACGTATT


 


201
GTTTGAAGTC CCAGCCATCC ACCGCGCCGC GTACTTCGTC GGCAATTTTC


 


251
CAAATTTGGC GGTGCAGTTG GGCGCGTTGT TGTATTTCGG TCATCATCGA


 


301
AATCCATAT. AAAAGTTAAA CAAATCAAAA TCGCCTGATA TTTTCAGACG


 


351
ATTTTTT.AC GGGCATTCAA ATTAA






This corresponds to the amino acid sequence <SEQ ID 1954; ORF 612.a>:










a612.pep




1
MGFGGNIAKK LAGVDEIAFD FDGIVFDFGR DDAVRHSGVI NTAVACLHIV


 


51
GKVFADKAVE KCAENVLFEV PAIHRAAYFV GNFPNLAVQL GALLYFGHHR


 


101
NPYXKLNKSK SPDIFRRFFX GHSN*






m612/a612 96.0% identity in 124 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1955>:










g613.seq




1
ATGTCGCGTT CGAGCCTGTC GAGGCGTTCG TTGAGGCGTT CCACGCCGTC


 


51
GCGCAGTCTG CTTATTTCGT CGaggcagtc ggcaagggct tcgttgccgg


 


101
tgtttGcgGA CTCGGGTTCG CGGGAAAATC CGCCGATTTG TTCGGCGATG


 


151
TTCCTGCCGA TTTgtttGAt GCCGTGTCCG ATGTCGGTGG CACGgctgcc


 


201
gatgcCTGCC TGCGTGCCGA AAATCCGTGC CAATTcgtCC GATGCGCGGG


 


251
AACGCAGGCT GCCGAGCAGG GACAGTACCG CgATGCCGAG GATGAGGTCG


 


301
CCTTCGAGCC TGATGTCGCC AGCCCCGGGT TCGCCGCCTT GGAGGATTTT


 


351
CCGTATCGCG CTGTTGCGGA AGGTAATTTC GGTGTCTGCA AAGCCGTTTC


 


401
CCGCCGAGAG CAAACCGTCT TCTGTGATGC GTCCCGCCAG TTTCAGCCCG


 


451
GCAATGTTCA GGGTCAGTGT TTTGCCTGCA AAGGAGGTAA GTTCCGAGCG


 


501
GCTGTCCGGG CTTTGCAGAA TCAGGCGGTT GATGATGGGG AGGAGGGCGG


 


551
ACATATTTTC TGATTGGGGC GGAGAATGCC TGTTGTTGCT GTTGCCGCTT


 


601
ATTTTACAGG CTTAA






This corresponds to the amino acid sequence <SEQ ID 1956; ORF 613.ng>:










g613.pep




1
MSRSSLSRRS LRRSTPSRSL LISSRQSARA SLPVFADSGS RENPPICSAM


 


51
FLPICLMPCP MSVARLPMPA CVPKIRANSS DARERRLPSR DSTAMPRMRS


 


101
PSSLMSPAPG SPPWRIFRIA LLRKVISVSA KPFPAESKPS SVMRPASFSP


 


151
AMFRVSVLPA KEVSSERLSG LCRIRRLMMG RRADIFSDWG GECLLLLLPL


 


201
ILQA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1957>:










m613.seq




1
ATGTCGCGTT CGAGCCGGTC GAGGCGTTCG TTGAGGCGTT CCACGCCGTC


 


51
GCGCAGTCTG CTTATTTCGT CGAGGCAGTC GGCAAGGGCT TCGTTGCCGA


 


101
TGTTTGCGGA CTCGGATTCG CGGGAAAATC CGCCGATTTG TTCGGCGATG


 


151
TTCCTGCCGA TTTGTTTGAT GCCGTGTCCG ATGTCGGCGG CACGGCTGCC


 


201
GATGTCTGCC TGCGTGCCGA AAATCCGTGC CAATTCGTCC GATGCGCGGG


 


251
AACGCAGGCT GCCGAGCAGG GACAGTACCG CGATGCCGAG GATGAGGTCG


 


301
CCTTCGAGCC CGATGTCGCC CGCCCCGGGT TCGCCTCCTT GGAGGATTTT


 


351
CTGTACCGCG CTGTTGCGGA AGGTAATTTC GGTGTCTGCA AAGCCGTTTC


 


401
CCGCCGAGAG CAAACCGTCT TCCGTGATGC GTCCCGCCAG TTTCAGCCCG


 


451
GCAATGTTCA GGGTCAGTGT TTTGCCTGCA AAGGCGGCAA GTTCCGAGCG


 


501
GCTGTCCGGG CTTTGCAGAA TCAGGCGGTT GATGATGGGG AGGAGGGCGG


 


551
ACATATTTTC TGATCGGGGC GGAGAATGCC TGTTGTTGCT GTTGCCGCTT


 


601
ATTTTACAGG CTTAA






This corresponds to the amino acid sequence <SEQ ID 1958; ORF 613>:










m613.pep




1
MSRSSRSRRS LRRSTPSRSL LISSRQSARA SLPMFADSDS RENPPICSAM


 


51
FLPICLMPCP MSAARLPMSA CVPKIRANSS DARERRLPSR DSTAMPRMRS


 


101
PSSPMSPAPG SPPWRIFCTA LLRKVISVSA KPFPAESKPS SVMRPASFSP


 


151
AMFRVSVLPA KAASSERLSG LCRIRRLMMG RRADIFSDRG GECLLLLLPL


 


201
ILQA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m613/g613 94.6% identity in 204 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1959>:










a613.seq




1
ATGTCGCGTT CGAGCCGGTC GAGGCGTTCG TTGAGGCGTT CCACGCCGTC


 


51
GCGCAGTCTG CTTATTTCGT CGAGGCAGTC GGCAAGGGCT TCGTTGCCGA


 


101
TGTTTGCGGA CTCGGGTTCG CGGGAAAATC TGCCGATTTG TTCGGCGATG


 


151
TTCCTGCCGA TTTGTTTGAT GCCGTGTCCG ATGTCGGCGG CACGGCTGCC


 


201
GATGTCTGCC TGCGTGCCGA AAATCCGTGC CAATTCGTCC GATGCGCGGG


 


251
AACGCAGGCT GCCGAGCAGG GACAGTACCG CGATGCCGAG GATGAGGTCG


 


301
CCTTCGAGCC CGATGTCGCC CGCCCCGGGT TCGCCGCCTT GGAGGATTTT


 


351
CTGTACCGCG CTGTTGCGGA AGGTGATTTC GGTGTCTGCA AAGCCGTTTC


 


401
CCGCCGAGAG CAAACCGTCT TCCGTGATGC GTCCCGCCAG TTTCAACCCG


 


451
GCAATGTTCA GGGTCAGTGT TTTGCCTGCG AAGGCGGCAA GTTCCGAGCG


 


501
GCTGTCCGGG CTTTGCAGAA TCAGGCGGTT GATGATGGGG AGGAGGGCGG


 


551
ACATATTTTC TGATCGGGGC GGAGAATGCC TGTTGTTGCT GTTGACGCTT


 


601
ATTTTACAGG CTTAA






This corresponds to the amino acid sequence <SEQ ID 1960; ORF 613.a>:










a613.pep




1
MSRSSRSRRS LRRSTPSRSL LISSRQSARA SLPMFADSGS RENLPICSAM


 


51
FLPICLMPCP MSAARLPMSA CVPKIRANSS DARERRLPSR DSTAMPRMRS


 


101
PSSPMSPAPG SPPWRIFCTA LLRKVISVSA KPFPAESKPS SVMRPASFNP


 


151
AMFRVSVLPA KAASSERLSG LCRIRRLMMG RRADIFSDRG GECLLLLLTL


 


201
ILQA*






m613/a613 98.0% identity in 204 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1961>:










g614.seq




1
AtggcTgcgt tcAacgcttt ggacggcaaa aaagaagaca acgggcaaat


 


51
cgaaTATTCT CAGTTCATCC GACAGGTCAA CAACGGCGAA GTATCCGGCG


 


101
TCAACATCGA AGGATCCGTC GTCAGCGGTT ACCTGATTAA AGGCGAGCGC


 


151
ACCGACAAAA GCACCTTCTT CACCAACGCG CCCTTGGATG ACAACCTGAT


 


201
TCAAACCCTT TTGAACAAAA ACGTCCGCGT AAAAGTAACG CCGGAAGAAA


 


251
AACCGAGCGC GCTGACTGCC CTGTTTTACA GCCTGCTGCC CGTCCTGCTG


 


301
CTGATTGGCG CATGGTTCTA CTTTATGCGT ATGCAGGCGG GCGGCGGCGG


 


351
AAAAGGCGGC GCATTCTCCT TCGGCAAAAG CCGCGCCCGC CTGCTGGACA


 


401
AAGATGCCAA CAAAGTTACC TTTGCCGATG TCGCCGGCTG CGACGAAGCC


 


451
AAAGAAGAAG TGCAGGAAAT CGTCGATTAC CTCAAAGCAC CGAACCGCta


 


501
tcaAAGcctc ggcggccgtg ttcCGCGCGG CATCCtgCtg gcgGgcagcc


 


551
CGGGAaccgg taaAACACTC TTGGCGAAAG CCATTGCAGG CGAGGCCGGC


 


601
GTGCCGTTCT TCAGCATTTC CGGTTCCGAT TTTGTCGAAA TGTTCGTCGG


 


651
TGTCGGTGCA AGCCGCGTCC GCGATATGTT CGAGCAGGCA AAGAAAAACG


 


701
CCCCATGCAT TATCTTTATC GACGAGATTG ACGCGGTAGG CCGCCAACGC


 


751
GGCGCAGgTT TGGGCGGCGG CAATGATGAG CGCGAGCAAA CATTAAACCA


 


801
ATTATTGGTT GAAATGGACG GTTTTGAGAG CAATCAGACT GTAATTGTGA


 


851
TTGCGGCAAC CAACCGCCCC GACGTACTCG ATCCTGCGCT GCAACGCCCC


 


901
GGCCGCTTCG ACCGCCAAGT CGTCGTCCCC CTGCCGGACA TCCGGGGGCG


 


951
CGAACAGatn ttGAACGTCC ATTCtaaAAA AGTGCcttTG gacgaATCTg


 


1001
tggaTTTATT GTCCCTCGCG CGCGGCACGC ccggtttTTc cggcgcggat


 


1051
tTggcgaaac tggtcaacga agcccccctg tttgccggcc gccgcaacaa


 


1101
agtgaaagtc gatcaaagcg attTGAAGAC GCCAAAGACA AAATCTATAT


 


1151
GGGTCCGGAA CGCCGCAGTA TGGTGA






This corresponds to the amino acid sequence <SEQ ID 1962; ORF 614.ng>:










g614.pep




1
MAAFNALDGK KEDNGQIEYS QFIRQVNNGE VSGVNIEGSV VSGYLIKGER


 


51
TDKSTFFTNA PLDDNLIQTL LNKNVRVKVT PEEKPSALTA LFYSLLPVLL


 


101
LIGAWFYFMR MQAGGGGKGG AFSFGKSRAR LLDKDANKVT FADVAGCDEA


 


151
KEEVQEIVDY LKAPNRYQSL GGRVPRGILL AGSPGTGKTL LAKAIAGEAG


 


201
VPFFSISGSD FVEMFVGVGA SRVRDMFEQA KKNAPCIIFI DEIDAVGRQR


 


251
GAGLGGGNDE REQTLNQLLV EMDGFESNQT VIVIAATNRP DVLDPALQRP


 


301
GRFDRQVVVP LPDIRGREQX LNVHSKKVPL DESVDLLSLA RGTPGFSGAD


 


351
LAKLVNEAPL FAGRRNKVKV DQSDLKTPKT KSIWVRNAAV W*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1963>:










m614.seq




1
ATGGCTGCGT TCAACGCTTT AGACGGTAAA AAAGAAGACA ACGGGCAAAT


 


51
CGAATACTCT CAGTTCATCC AACAGGTCAA CAACGGCGAA GTATCCGGCG


 


101
TCAACATCGA AGGATCCGTC GTCAGCGGCT ACCTGATTAA GGGCGAGCGC


 


151
ACCGACAAAA GCACTTTCTT CACCAACGCG CCTTTGGACG ACAACCTAAT


 


201
TAAAACACTG CTCGACAAAA ACGTCCGCGT AAAAGTAACG CCGGAAGAAA


 


251
AACCGAGCGC GCTGGCTGCC CTGTTTTACA GCCTGCTGCC CGTCCTGCTG


 


301
CTGATTGGCG CATGGTTCTA CTTCATGCGT ATGCAGACGG GCGGCGGCGG


 


351
AAAAGGCGGC GCATTCTCAT TCGGTAAAAG CCGCGCCCGC CTGCTGGACA


 


401
AAGATGCCAA CAAAGTGACC TTTGCCGATG TCGCCGGCTG CGACGAAGCC


 


451
AAAGAAGAAG TACAGGAAAT CGTCGATTAC CTCAAAGCGC CGAACCGCTA


 


501
TCAAAGCCTG GGCGGGCGCG TGCCGCGCGG CATCCTGCTG GCGGGCAGCC


 


551
CGGGTACGGG TAAGACGCTT TTGGCGAAAG CGATTGCAGG CGAAGCCGGC


 


601
GTGCCGTTCT TCAGCATTTC AGGTTCCGAC TTTGTCGAAA TGTTCGTCGG


 


651
TGTCGGTGCG AGCCGCGTCC GCGATATGTT CGAGCAGGCG AAGAAAAACG


 


701
CCCCCTGCAT CATCTTTATC GACGAGATTG ACGCAGTCGG CCGCCAACGC


 


751
GGCGCAGGTT TGGGCGGCGG CAATGATGAG CGCGAGCAAA CATTAAACCA


 


801
ATTGTTGGTT GAAATGGACG GTTTTGAGAG CAATCAGACT GTAATTGTGA


 


851
TTGCGGCAAC CAACCGCCCC GACGTACTCG ATCCTGCGCT GCAACGCCCC


 


901
GGCCGTTTCG ACCGCCAAGT GGTTGTCCCC CTGCCGGACA TCCGAGGGCG


 


951
CGAACAGATT TTGAACGTCC ATTCTAAAAA AGTGCCTTTG GACGAATCTG


 


1001
TGGATTTATT GTCCCTCGCG CGCGGCACGC CGGGTTTTTC CGGCGCGGAT


 


1051
TTGGCGAACT TGGTCAACGA AGCCGCCCTG TTTGCCGGCC GCCGCAATAA


 


1101
AGTCAAAGTC GATCAGAGCG ATTTGAAGAC GCCAAAGACA AAATCTATAT


 


1151
GGGTCCGGAA CGCCGCAGTA TGGTGA






This corresponds to the amino acid sequence <SEQ ID 1964; ORF 614>:










m614.pep




1
MAAFNALDGK KEDNGQIEYS QFIQQVNNGE VSGVNIEGSV VSGYLIKGER


 


51
TDKSTFFTNA PLDDNLIKTL LDKNVRVKVT PEEKPSALAA LFYSLLPVLL


 


101
LIGAWFYFMR MQTGGGGKGG AFSFGKSRAR LLDKDANKVT FADVAGCDEA


 


151
KEEVQEIVDY LKAPNRYQSL GGRVPRGILL AGSPGTGKTL LAKAIAGEAG


 


201
VPFFSISGSD FVEMFVGVGA SRVRDMFEQA KKNAPCIIFI DEIDAVGRQR


 


251
GAGLGGGNDE REQTLNQLLV EMDGFESNQT VIVIAATNRP DVLDPALQRP


 


301
GRFDRQVVVP LPDIRGREQI LNVHSKKVPL DESVDLLSLA RGTPGFSGAD


 


351
LANLVNEAAL FAGRRNKVKV DQSDLKTPKT KSIWVRNAAV W*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m614/g614 98.0% identity in 391 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1965>:










a614.seq




1
ATGGCTGCGT TCAACGCTTT AGACGGTAAA AAAGAAGACA ACGGGCAAAT


 


51
CGAATATTCT CAGTTCATCC AACAGGTCAA CAACGGCGAA GTATCCGGCG


 


101
TCAACATCGA AGGATCCGTC GTCAGCGGCT ACCTGATTAA GGGCGAGCGC


 


151
ACCGACAAAA GCACCTTCTT CACCAACGCG CCTTTGGACG ACAACCTGAT


 


201
TAAAACACTG CTCGACAAAA ACGTCCGTGT AAAAGTAACG CCGGAAGAAA


 


251
AACCGAGCGC GCTGGCTGCC CTGTTTTACA GCCTGCTGCC CGTCCTGCTG


 


301
CTGATTGGCG CGTGGTTCTA CTTTATGCGT ATGCAGACGG GCGGCGGCGG


 


351
AAAAGGCGGC GCATTCTCAT TCGGCAAAAG CCGCGCCCGC CTACTGGACA


 


401
AAGATGCCAA CAAAGTTACC TTTGCCGATG TCGCCGGCTG CGACGAAGCC


 


451
AAAGAAGAAG TGCAGGAAAT CGTCGATTAC CTCAAAGCGC CGAACCGCTA


 


501
TCAAAGCCTG GGCGGGCGCG TGCCGCGCGG CATCCTGCTG GCGGGCAGCC


 


551
CGGGTACGGG TAAGACGCTT TTGGCGAAAG CGATTGCAGG CGAAGCCGGC


 


601
GTGCCGTTCT TCAGCATTTC AGGTTCCGAC TTTGTCGAAA TGTTCGTCGG


 


651
TGTCGGTGCA AGCCGCGTCC GCGATATGTT CGAGCAGGCG AAGAAAAACG


 


701
CCCCCTGCAT CATCTTTATC GACGAGATTG ACGCAGTCGG CCGCCAACGC


 


751
GGCGCAGGTT TGGGCGGCGG TAATGATGAG CGCGAGCAAA CATTAAACCA


 


801
ATTGTTGGTT GAAATGGACG GTTTTGAGAG CAATCAGACT GTAATTGTGA


 


851
TTGCGGCAAC CAACCGCCCC GACGTACTCG ATCCTGCGCT GCAACGCCCC


 


901
GGCCGTTTCG ACCGCCAAGT GGTTGTCCCC CTGCCGGACA TCCGGGGGCG


 


951
CGAACAGATT TTGAACGTCC ACTCTAAAAA AGTGCCTTTG GACAAATCTG


 


1001
TGGATTTATT GTCCCTCGCG CGCGGCACGC CGGGTTTTTC CGGCGCGGAT


 


1051
TTGGCGAACT TGGTCAACGA AGCCGCCCTG TTTGCCGGCC GCCGCAATAA


 


1101
AGTCAAAGTC GATCAGAGCG ATTTGAAGAC GCCAAAGACA AAATCTATAT


 


1151
GGGTCCGGAA CGCCGCAGTA TGGTGA






This corresponds to the amino acid sequence <SEQ ID 1966; ORF 614.a>:










a614.pep




1
MAAFNALDGK KEDNGQIEYS QFIQQVNNGE VSGVNIEGSV VSGYLIKGER


 


51
TDKSTFFTNA PLDDNLIKTL LDKNVRVKVT PEEKPSALAA LFYSLLPVLL


 


101
LIGAWFYFMR MQTGGGGKGG AFSFGKSRAR LLDKDANKVT FADVAGCDEA


 


151
KEEVQEIVDY LKAPNRYQSL GGRVPRGILL AGSPGTGKTL LAKAIAGEAG


 


201
VPFFSISGSD FVEMFVGVGA SRVRDMFEQA KKNAPCIIFI DEIDAVGRQR


 


251
GAGLGGGNDE REQTLNQLLV EMDGFESNQT VIVIAATNRP DVLDPALQRP


 


301
GRFDRQVVVP LPDIRGREQI LNVHSKKVPL DKSVDLLSLA RGTPGFSGAD


 


351
LANLVNEAAL FAGRRNKVKV DQSDLKTPKT KSIWVRNAAV W*






m614/a614 99.7% identity in 391 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1967>:










g615.seq




1
ATGTGGAAAC GGCGGCGGCG CGGTGtcggC AGCTTtgaag agcagcGaAT


 


51
agatgCCGCC GGCAAACCAC AATGCGGAAa gcaggCtgaa gcGGTTgcgC


 


101
GGCagcTTca tGCCGCCTCC TcGTCCaGCC ACGtttGgca gattttggac


 


151
aggcgcAGga ATTTGCcgCc gcgtgcggCA agtatgtcgc gcCAttgtgc


 


201
cacttcttcg gcggacggTG cttcgtcgaT gctgCATTCG TACagcagga


 


251
aatcgagggt ttcttcgatg acggGgatgg AttccgTTTG GataAgCTgc


 


301
ttgagttcgt tcatgactGt TCgGATAcgg aaatcgggaa aatgccgtct


 


351
gAaagggctt CAGACGGCat tggATTATTT GCTGTGCAGG AAgcgcgttg


 


401
cctcttccca tttgcCGGAA AtgATGTCGg gtacggcctg cAGGGATttg


 


451
gCGACGGcat cgtcgatttg ccgGcggtgc ttCcgcgctc ggtttGTTca


 


501
agacgtagcc gaCGACGagg ttgcggtcGC CGGGGtggcC GATGCCGAGG


 


551
CGCAGGCGGt aatagtctgC CGTGCCGAGT TTTGCctgAA TGTCTTTCAA


 


601
GCCGTTGTGT CcgcCGttgc cgcCGCCGAG TTTGAATTTg ATCCGTCCGC


 


651
AAGGGATGTC GAGTTCGTCG TGGACGACGA GGATTTCTTC GGGTTTGATT


 


701
TTGTAGAACT GTGCAAGCGC GGCAACCGCC TGTCCGGAAC GGTTCATGAA


 


751
CGTGGCCGGT TTGAGCAGCC AAACATCGCC GTCGGGCAGG GCGGCGCGGG


 


801
CAACTTCGCC GAAGAATTTT TTTTCTTCTT TAAACGAAGC CTTCCATTTC


 


851
CACGCCAGTT CGTCGAGGAA CCAAAAGCCC GCATTGTGGC GGGTCTGTTC


 


901
GTATTCTTTG CCCGGGTTGC CCAAGCCGAC AACCATTTTG ATTGTGttcg


 


951
acatgataTT TtccgtgTTT CTgTCGaatg cggtCtgaAG GCTTCAGacg


 


1001
gcatggTtaT TCTTCTTgaT TTtgaACgcg tgtgcggCGC GCTTCTTTGG


 


1051
GGTCGATCAA CAGCGGGCGG TACACTTCGA TGCGGTCGCC GTCGCGCAGC


 


1101
GGCGTGTCGT CTTTGA






This corresponds to the amino acid sequence <SEQ ID 1968; ORF 615.ng>:










g615.pep




1
MWKRRRRGVG SFEEQRIDAA GKPQCGKQAE AVARQLHAAS SSSHVWQILD


 


51
RRRNLPPRAA SMSRHCATSS ADGASSMLHS YSRKSRVSSM TGMDSVWISC


 


101
LSSFMTVRIR KSGKCRLKGL QTALDYLLCR KRVASSHLPE MMSGTACRDL


 


151
ATASSICRRC FRARFVQDVA DDEVAVAGVA DAEAQAVIVC RAEFCLNVFQ


 


201
AVVSAVAAAE FEFDPSARDV EFVVDDEDFF GFDFVELCKR GNRLSGTVHE


 


251
RGRFEQPNIA VGQGGAGNFA EEFFFFFKRS LPFPRQFVEE PKARIVAGLF


 


301
VFFARVAQAD NHFDCVRHDI FRVSVECGLK ASDGMVILLD FERVCGALLW


 


351
GRSTAGGTLR CGRRRAAACR L*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1969>:









m615.seq Length: 1116










1
ATGCGGAAAA GGCGGTGGCG CGGTTTCGGC AGCTTTGAAA AGCAGTGAGT



 


51
AAATGCTGCC TGCAAACCAC AATGCCGAGA GCAGGATAAA GCGGTTGCGT


 


101
GGCAGATTCA TGCTTGTTCC TCTTCAAGCC ATGTCTGGCA TAGTTTGGAT


 


151
AGGCGCAGGA ATTTTCCGCC GCGTGCGGCC AGCATATCGC GCCAAACGGC


 


201
AATTTCTTCG GCGGAGGGGG CATCGTCTAT GCTGCATTCG TAGAGCAGGA


 


251
AATCGAGGGT TTCTTCGATG ACGGGGATGG ATTCGGTTTG GATAAGCTGC


 


301
TTGAGTTCGG TCATGACTGT TCGGATATGG AAATCGGGAA CATGCCGTCT


 


351
GAAAGGGCTT CAGACGGCAT CGGGTCATTT GCTGTGCAGG AAGCGGGTTG


 


401
CTTCTTCCCA TTTGCCGGCA AGGATGTCGG GTATGGCTTG CAGGGATTTG


 


451
GCGACGGCAT CGTCAATCTG TCGGCGGTGT .TCCGTACTG GGTTTGTTCA


 


501
GGACATAGCC GACGACGAGG TTGCGGTCGC CCGGGTGGCC GATGCCGAGG


 


551
CGCAGGCGGT AATAGTCTGC CGTGCCGAGT TTTGCCTGAA TGTCTTTCAA


 


601
GCCGTTGTGT CCGCCGTTGC CGCCGCCGAG TTTGAATTTG ATCCGTCCGC


 


651
AGGGAATGTC GAGTTCGTCG TGGACGACGA GGATTTCTTC GGGTTTGATT


 


701
TTGTAGAACT GTGCAAGCGC GGCAACTGCC TGTCCGGAAC GGTTCATGAA


 


751
CGTGGCAGGT TTGAGCAGCC AAACGTCGCC GTCGGGCAGG GCGGCACGGG


 


801
CGACTTCGCC GAAGAATTTT TTTTCTTCTT TAAATGAAGC CTTCCATTTC


 


851
CACGCCAGTT CGTCGAGGAA CCAAAAACCC GCATTGTGGC GTGTCTGTTC


 


901
GTATTCTTTG CCCGGGTTGC CCAAGCCGAC AACCATTTTG ATTGTGTTTG


 


951
ACATGATATT TTCCGTGTTT CTGTCGAATG CTGTCTGAAG GCTTCAGACG


 


1001
GCATGGTTAT TCTTCTTGAT TTTGAACGCG TTTGCGGCGC GCTTCTTTGG


 


1051
GGTCGATCAA CAGCGGGCGG TACACTTCGA TGCGGTCGCC GTCGCGCAGC


 


1101
GGCGTGTCGT CTTTGA






This corresponds to the amino acid sequence <SEQ ID 1970; ORF 615>:









m615.pep Length: 372










1
MRKRRWRGFG SFEKQXVNAA CKPQCREQDK AVAWQIHACS SSSHVWHSLD



 


51
RRRNFPPRAA SISRQTAISS AEGASSMLHS XSRKSRVSSM TGMDSVWISC


 


101
LSSVMTVRIW KSGTCRLKGL QTASGHLLCR KRVASSHLPA RMSGMACRDL


 


151
ATASSICRRC XRTGFVQDIA DDEVAVARVA DAEAQAVIVC RAEFCLNVFQ


 


201
AVVSAVAAAE FEFDPSAGNV EFVVDDEDFF GFDFVELCKR GNCLSGTVHE


 


251
RGRFEQPNVA VGQGGTGDFA EEFFFFFKXS LPFPRQFVEE PKTRIVACLF


 


301
VFFARVAQAD NHFDCVXHDI FRVSVECCLK ASDGMVILLD FERVCGALLW


 


351
GRSTAGGTLR CGRRRAAACR L*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m615/g615 86.8% identity in 371 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1971>:










a615.seq




1
ATGCGGAAAC GGCGGCGGCG CGGTGTCGGC AGCTTTGAAG AGCAGCGAAT


 


51
AGATGCCGCC GGCAAACCAC AATGCGGAAA GCAGGCTGAA GCGGTTGCGC


 


101
GGCAGCTTCA TGCCGCCTCC TCGTCCAGCC ACGTTTGGCA GATTTTGGAC


 


151
AGGCGCAGGA ATTTGCCGCC GCGTGCGGCA AGTATGTCGC GCCATTGTGC


 


201
CACTTCTTCG GCGGATGGTG CGTCGTCGAT GCTGCATTCG TACAGCAGGA


 


251
AATCGAGGGT TTCTTCGATG ACGGGGATGG ATTCGGTTTG GATAAGCTGC


 


301
TTGAGTTCGG TCATGACTGT TCGGATATGG AAATCGGGAA CATGCCGTCT


 


351
GAAAGGGCTT CAGACGGCAT CGGGTCATTT GCTGTGCAGG AAGCGGGTTG


 


401
CCTCTTCACA TTTGCCGGCA AGGATGTCGG GTATGGCTTG CAGGGATTTG


 


451
GCGACGGCAT CGTCAATCTG TCGGCGGTG. TTCCGTACTG GGTTTGTTCA


 


501
GGACATAGCC GACGACGAGG TTGCGGTCGC CCGGGTGGCC GATGCCGAGG


 


551
CGCAGGCGGT AATAGTCTGC CGTGCCGAGT TTTGCCTGAA TGTCTTTCAA


 


601
GCCGTTGTGT CCACCGTTGC CGCCGCCGAG TTTGAATTTG ATCCGTCCGC


 


651
AGGGAATGTC GAGTTCGTCG TGGACGACGA GGATTTCTTC GGGTTTGATT


 


701
TTATAAAACT GCGCAAGGGC GGCAACTGCC TGTCCGGAAC GGTTCATGAA


 


751
CGTGGTCGGC TTGAGCAGCC AGACATCGCC GTCGGGCAGG GTAGCACGGG


 


801
CGACTTCGCC GAAGAATTTT TTTTCTTCTT TAAATGAAGC CTTCCATTTC


 


851
CACGCCAGTT CGTCGAGGAA CCAAAAACCC GCATTGTGGC GTGTCTGTTC


 


901
GTATTCTTTG CCCGGGTTGC CCAAGCCGAC AACCATTTTG ATTGTGTTTG


 


951
ACATGATATT TTCCGTGTTT CTGCCGAATG CCGTCTGAAG GCTTCAGACG


 


1001
GCATGGTTAT TCTTCTTGAT TTTGAACGCG TTTGCGGCGC GCTTCTTTGG


 


1051
GGTCGATCAA CAGCGGGCGG TACACTTCGA TGCGGTCGCC GTCGCGCAGC


 


1101
GGCGTGTCGT CTTTGA






This corresponds to the amino acid sequence <SEQ ID 1972; ORF 615.a>:










a615.pep




1
MRKRRRRGVG SFEEQRIDAA GKPQCGKQAE AVARQLHAAS SSSHVWQILD


 


51
RRRNLPPRAA SMSRHCATSS ADGASSMLHS YSRKSRVSSM TGMDSVWISC


 


101
LSSVMTVRIW KSGTCRLKGL QTASGHLLCR KRVASSHLPA RMSGMACRDL


 


151
ATASSICRRX FRTGFVQDIA DDEVAVARVA DAEAQAVIVC RAEFCLNVFQ


 


201
AVVSTVAAAE FEFDPSAGNV EFVVDDEDFF GFDFIKLRKG GNCLSGTVHE


 


251
RGRLEQPDIA VGQGSTGDFA EEFFFFFK*S LPFPRQFVEE PKTRIVACLF


 


301
VFFARVAQAD NHFDCV*HDI FRVSAECRLK ASDGMVILLD FERVCGALLW


 


351
GRSTAGGTLR CGRRRAAACR L*






m615/a615 90.3% identity in 371 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1973>:










g616.seq




1
atgtcgaaCA CAATCAAAAT GGTTGTCGGC TTGGGCAACC CGGGCAAAGA



 


51
ATACGAACAG ACCCGCCACA ATGCGGGCTT TTGGTTCCTC GACGAACTGG


 


101
CGTGGAAATG GAAGGCTTCG TTTAAAGAAG AAAAAAAATT CTTCGGCGAA


 


151
GTTGCCCGCG CCGCCCTGCC CGACGGCGAT GTTTGGCTGC TCAAACCGGC


 


201
CACGTTCATG AACCGTTCCG GACAGGCGGT TGCCGCGCTT GCACAGTTCT


 


251
ACAAAATCAA ACCCGAAGAA ATCCTCGTCG TCCACGACGA ACTCGACATC


 


301
CCTTGCGGAC GGATcAAATT CAAACTCGGC GgcggcaaCG gcgGACACAA


 


351
CGGCTTGAAA GACATTcagG CAAAACTCGG CACGGcagac tattaCCGCC


 


401
TGCGCCTCGG CATCGgccaC CCCGGCgacc gcaacctCGT CGtcggctac


 


451
gtcttgAACa aaccgagcgc gGaagcaccg Ccggcaaatc gacgatgCCG


 


501
TCGccaaATC CCTgcaggcc gtaccCGACA TcaTTTCCGg caaatgggaa


 


551
gaggcaacgc gcTTCCTGCA CAGCAAATAA TccaatGCCG TCTGaagccc


 


601
ttTcagacgg cattttcccg atttccgTAT CcGAaCagtc atgaacgaac


 


651
tcaagcAGcT tatCCAAAcg gaaTccatcC ccgtcatcga agaaaccctc


 


701
gatttcctgc tGTACGAATG cagcAtcgac gaagCAccgt ccgccgaaga


 


751
agtggcacaa TGgcgcgaca tactTGccgc acgcgGcgGC AAATtcCTgc


 


801
gcctgtccaa aatctgcCaa aCGTGGCtGG ACgAGGAGGC GGCatgAAgc


 


851
tGCCGcgcAA CCgcttcaGc ctgctTTCCG CATTGTGGTT TGCCGGCGGc


 


901
atctATtCgc tgctcttcaA AGCTGccgaC ACCGCGCCGC CGCCGTTTCC


 


951
ACATTtcgaC AAAGCAGCAC ACCTTGCCCT GTTTTTCGCA CAaatCTTgt


 


1001
tTctGGCCAA AGCATTCAAA ACCGGAAAAC TTCCCATCCC CTACCGCAGC


 


1051
CTGATTGCGT TCGCCTTCTG TTTTGCCGTC GGCAGCGAAT GCGCGCAGGC


 


1101
ATGGTTTACC GCAACGCGAA CCGGCAGTTT GGGCGATGTC CTTGCCgACC


 


1151
TGACGGGCGC AGCCCTTGCC CTCTTTGCCG CGCGTTCTGC CTGCCGcccg


 


1201
gactaa






This corresponds to the amino acid sequence <SEQ ID 1974; ORF 616.ng>:










g616.pep




1
MSNTIKMVVG LGNPGKEYEQ TRHNAGFWFL DELAWKWKAS FKEEKKFFGE



 


51
VARAALPDGD VWLLKPATFM NRSGQAVAAL AQFYKIKPEE ILVVHDELDI


 


101
PCGRIKFKLG GGNGGHNGLK DIQAKLGTAD YYRLRLGIGH PGDRNLVVGY


 


151
VLNKPSAEAP PANRRCRRQI PAGRTRHHFR QMGRGNALPA QQIIQCRLKP


 


201
FQTAFSRFPY PNSHERTQAA YPNGIHPRHR RNPRFPAVRM QHRRSTVRRR


 


251
SGTMARHTCR TRRQIPAPVQ NLPNVAGRGG GMKLPRNRFS LLSALWFAGG


 


301
IYSLLFKAAD TAPPPFPHFD KAAHLALFFA QILFLAKAFK TGKLPIPYRS


 


351
LIAFAFCFAV GSECAQAWFT ATRTGSLGDV LADLTGAALA LFAARSACRP


 


401
D*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1975>:










m616.seq




1
ATGTCAAACA CAATCAAAAT GGTTGTCGGC TTGGGCAACC CGGGCAAAGA



 


51
ATACGAACAG ACACGCCACA ATGCGGGTTT TTGGTTCCTC GACGAACTGG


 


101
CGTGGAAATG GAAGGCTTCA TTTAAAGAAG AAAAAAAATT CTTCGGCGAA


 


151
GTCGCCCGTG CCGCCCTGCC CGACGGCGAC GTTTGGCTGC TCAAACCTGC


 


201
CACGTTCATG AACCGTTCCG GACAGGCAGT TGCCGCGCTT GCACAGTTCT


 


251
ACAAAATCAA ACCCGAAGAA ATCCTCGTCG TCCACGACGA ACTCGACATT


 


301
CCCTGCGGAC GGATCAAATT CAAACTCGGC GGCGGCAACG GCGGACACAA


 


351
CGGCTTGAAA GACATTCAGG CAAAACTCGG CACGGCAGAC TATTACCGCC


 


401
TGCGCCTCGG CATCGGCCAC CCGGGCGACC GCAACCTCGT CGTCGGCTAT


 


451
GTCCTGAACA AACCCAGTAC GGAACA.CCG CCGACAGATT GACGATGCCG


 


501
TCGCCAAATC CCTGCAAGCC ATACCCGACA TCCTTGCCGG CAAATGGGAA


 


551
GAAGCAACCC GCTTCCTGCA CAGCAAATGA CCCGATGCCG TCTGAAGCCC


 


601
TTTCAGACGG CATGTTCCCG ATTTCCATAT CCGAACAGTC ATGACCGAAC


 


651
TCAAGCAGCT TATCCAAACC GAATCCATCC CCGTCATCGA AGAAACCCTC


 


701
GATTTCCTGC TCTACGAATG CAGCATAGAC GATGCCCCCT CCGCCGAAGA


 


751
AATTGCCGTT TGGCGCGATA TGCTGGCCGC ACGCGGCGGA AAATTCCTGC


 


801
GCCTATCCAA ACTATGCCAG ACATGGCTTG AAGAGGAACA AGCATGAATC


 


851
TGCCACGCAA CCGCTTTATC CTGCTCTCGG CATTGTGGTT TGCAGGCAGC


 


901
ATTTACTCAC TGCTTTTCAA AGCTGCCGAA ACCGCGCCAC CGCCTTTTCC


 


951
GCATTTTGAC AAAGTGGCGC ACCTCGCCCT GTTTTTCGCA CAAATCTGGC


 


1001
TTCTGACCAA AGCATTCAGA ACCGACAACC GCCCCATCCC CTATCGCAGC


 


1051
CTGATGGTCT TTGCCCTCTG TTTCGCCCTC TTCAGCGAAT GCGCGCAGGC


 


1101
ATGGTTTACC GCAACGAGAA CCGGCAGTTT GGGCGATGTC CTTGCCGACC


 


1151
TGACGGGCGC AGCCCTTGCC CTCTTTACCG CGCGAGCTGC CTGCCGCCCG


 


1201
GACTAA






This corresponds to the amino acid sequence <SEQ ID 1976; ORF 616>:










m616.pep




1
MSNTIKMVVG LGNPGKEYEQ TRHNAGFWFL DELAWKWKAS FKEEKKFFGE



 


51
VARAALPDGD VWLLKPATFM NRSGQAVAAL AQFYKIKPEE ILVVHDELDI


 


101
PCGRIKFKLG GGNGGHNGLK DIQAKLGTAD YYRLRLGIGH PGDRNLVVGY


 


151
VLNKPSTEXP PTDXRCRRQI PASHTRHPCR QMGRSNPLPA QQMTRCRLKP


 


201
FQTACSRFPY PNSHDRTQAA YPNRIHPRHR RNPRFPALRM QHRRCPLRRR


 


251
NCRLARYAGR TRRKIPAPIQ TMPDMAXRGT SMNLPRNRFI LLSALWFAGS


 


301
IYSLLFKAAE TAPPPFPHFD KVAHLALFFA QIWLLTKAFR TDNRPIPYRS


 


351
LMVFALCFAL FSECAQAWFT ATRTGSLGDV LADLTGAALA LFTARAACRP


 


401
D*






m616/g616 86.0% identity in 401 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1977>:










a616.seq




1
ATGTCAAACA CAATCAAAAT GGTTGTCGGC TTGGGCAACC CGGGCAAAGA



 


51
ATACGAACAG ACACGCCACA ATGCGGGTTT TTGGTTCCTC GACGAACTGG


 


101
CGTGGAAATG GAAGGCTTCA TTTAAAGAAG AAAAAAAATT CTTCGGCGAA


 


151
GTCGCCCGTG CTACCCTGCC CGACGGCGAT GTCTGGCTGC TCAAGCCGAC


 


201
CACGTTCATG AACCGTTCCG GACAGGCAGT TGCCGCCCTT GCGCAGTTTT


 


251
ATAAAATCAA ACCCGAAGAA ATCCTCGTCG TCCACGACGA ACTCGACATT


 


301
CCCTGCGGAC GGATCAAATT CAAACTCGGC GGCGGCAACG GTGGACACAA


 


351
CGGCTTGAAA GACATTCAGG CAAAACTCGG CACGGCAGAC TATTACCGCC


 


401
TGCGCCTCGG CATCGGCCAC CCGGGCGACC GCAACCTCGT CGTCGGCTAT


 


451
GTCCTGAACA AACCCAGTAC GGAA.CACCG CCGACAGATT GACGATGCCG


 


501
TCGCCAAATC CCTGCAAGCC ATACCCGACA TCCTTGCCGG CAAATGTGAA


 


551
GAGGCAACCC GCTTCCTGCA CAGCAAATGA CCCGATGCCG TCTGAAGCCC


 


601
TTTCAGACGG CATGTTCCCG ATTTCCATAT CCGAACAGTC ATGACCGAAC


 


651
TCAAGCAGCT TATCCAAACC GAATCCATCC CCGTCATCGA AGAAACCCTC


 


701
GATTTCCTGC TGTACGAATG CAGCATCGAC GACGCACCAT CCGCCGAAGA


 


751
AGTGGCACAA TGGCGCGACA TACTTGCCGC ACGCGGCGGC AAATTCCTGC


 


801
GCCTGTCCAA AATCTGCCAA ACGTGGCTGG ACGAGGAGGC GGCATGAAGC


 


851
TGCCGCGCAA CCGCTTCAGC CTGCTTTCCG CATTGTGGTT TGCCGGCGGC


 


901
ATCTATTCGC TGCTCTTCAA AGCTGCCGAC ACCGCGCCGC CGCCGTTTCC


 


951
GCATTTCGAC AAAGCAGCAC ACCTTGCCCT GTTTTTCGCA CAAATCTGGC


 


1001
TTTTGACCAA AGCATTCAAA ACCGGAAAAC TTCCCATCCC CTACCGCAGC


 


1051
CTGATGGTCT TTGCCCTCTG TTTCGCCCTC TTCAGCGAAT GCGCGCAGGC


 


1101
ATGATTTACC GCAACGAGAA CCGGCAGTTT GGGCGATGTT CTTGCCGATA


 


1151
TGGCAGGTAC GGTTCTCGCA CTCTTTGCCG CCCGCGCCGC CGACCGCCCG


 


1201
GACTGA






This corresponds to the amino acid sequence <SEQ ID 1978; ORF 616.a>:










a616.pep




1
MSNTIKMVVG LGNPGKEYEQ TRHNAGFWFL DELAWKWKAS FKEEKKFFGE



 


51
VARATLPDGD VWLLKPTTFM NRSGQAVAAL AQFYKIKPEE ILVVHDELDI


 


101
PCGRIKFKLG GGNGGHNGLK DIQAKLGTAD YYRLRLGIGH PGDRNLVVGY


 


151
VLNKPSTEXP PTD*RCRRQI PASHTRHPCR QM*RGNPLPA QQMTRCRLKP


 


201
FQTACSRFPY PNSHDRTQAA YPNRIHPRHR RNPRFPAVRM QHRRRTIRRR


 


251
SGTMARHTCR TRRQIPAPVQ NLPNVAGRGG GMKLPRNRFS LLSALWFAGG


 


301
IYSLLFKAAD TAPPPFPHFD KAAHLALFFA QIWLLTKAFK TGKLPIPYRS


 


351
LMVFALCFAL FSECAQA*FT ATRTGSLGDV LADMAGTVLA LFAARAADRP


 


401
D*






m616/a616 90.0% identity in 401 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1979>:










g619.seq




1
ATGCCGTCTG AAAAAAATAT CGGTTTTATG GCAGGAAGCA GCCGTCCGTT



 


51
GCGGGTCGCC TTTGCGCTGT TGCTGGTTTC CTGCATCCTG TTTATGACGC


 


101
TCAACGTCAA AGGAGATTGG GACTTTGTCT TGCACCTGCG CCTGACCAAG


 


151
CTTGCCGCGC TGCTGATGGT CGCCTATGCG GTCGGCGTGT CCACTCAACT


 


201
CTTCCAAACG CTGACCAACA ACCCGATTCT GACCCCTTCG ATTTTGGGTT


 


251
TCGATTCGCT GTATGTGTTT TTGCAGACCT TGCTGgtGTT TACGTtcgGC


 


301
GGCGTGGGCT ATAcatccct gccgttgacg gGCAAATTCG GCTTTGAACT


 


351
GGTTGTTATG ATGGGCGGCT CGCTGCTGCT GTTTTACACG CTCATCCGTC


 


401
AGGGCGGGCG CGATTTGCCG CACATGATTT TAATCGGCGT GATTTTCGGG


 


451
ATTTTGTTCC GCAGCCTTTC CTCGCTGCTT TCGCGCATGA TAGACCCCGA


 


501
AGAATTTACC GCCGCGCAGG CGAATATGTT TGCCGGATTC AATACCGTCC


 


551
GCAGCGAGCT TTTAGGCATA GGCGCGCTGG TCCTGCTCGT CAGCGCGGCG


 


601
GTCGTTTGGC ACGAACGCTA CCGCTCGGAC GTACACCTTT TGGGGCGCGA


 


651
CCAAGCCGTC AATTTGGGCA TCAGCTACAC GCGCAACACC TTATGGATAC


 


701
TGCTTTGGAT TGCCGCATTG GTGGCGACGG CGACCGCCGT TGTCGGCCCG


 


751
GTGAGCTTTT TCGGGCTTCT CGCCGCCTCG CTTGCCAACC ACTTTTCCCc


 


801
gtCCGTGCGC CATTCCGTCC GCCTGCcgat gacggtttGC gtcgGcggCA


 


851
TCCTCTTGgt cggCggacaA ACCGTATTCG AACACTTCTT GGGCATGAag


 


901
gCggTATTAA GCGTGGTGGt cgAATTTGCG ggcggactcG TTTTCCTCTA


 


951
TCTCGTTTTA AAACACAAAA AATGA






This corresponds to the amino acid sequence <SEQ ID 1980; ORF 619.a>:










g619.pep




1
MPSEKNIGFM AGSSRPLRVA FALLLVSCIL FMTLNVKGDW DFVLHLRLTK



 


51
LAALLMVAYA VGVSTQLFQT LTNNPILTPS ILGFDSLYVF LQTLLVFTFG


 


101
GVGYTSLPLT GKFGFELVVM MGGSLLLFYT LIRQGGRDLP HMILIGVIFG


 


151
ILFRSLSSLL SRMIDPEEFT AAQANMFAGF NTVRSELLGI GALVLLVSAA


 


201
VVWHERYRSD VHLLGRDQAV NLGISYTRNT LWILLWIAAL VATATAVVGP


 


251
VSFFGLLAAS LANHFSPSVR HSVRLPMTVC VGGILLVGGQ TVFEHFLGMK


 


301
AVLSVVVEFA GGLVFLYLVL KHKK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1981>:










m619.seq




1
ATGCCGTCTG AAAAAAATAT CGGTTTTATG GCAGGAAGCA GCCGCCCGTT



 


51
GTGGGTCGCC TTTGCGCTGT TGCTGGTTTC CTGCGTCCTG TTTATGACGC


 


101
TCAACGTCAA AGGCGATTGG GATTTTGTTT TGCAACTGCG GCTGACCAAA


 


151
CTTGCCGCGC TGCTGATGGT CGCCTATGCG GTCGGCGTGT CCACGCAACT


 


201
CTTCCAAACG CTGACCAATA ATCCGATTCT GACCCCTTCA ATTTTGGGTT


 


251
TCGATTCGCT GTATGTGTTT TTGCAGACCT TGCTGGTGTT TACGTTCGGC


 


301
GGCGTGGGCT ATGCTTCCCT GCCGTTGACG GGCAAATTCG GCTTTGAACT


 


351
GGTCGTCATG ATGGGCGGCT CGCTGCTGCT GTTCTACACG CTCATCAAAC


 


401
AGGGCGGACG CGATTTGTCG CGCATGATTT TAATCGGCGT GATTTTCGGG


 


451
ATTTTGTTCC GCAGCCTGTC GTCGCTGCTT TCGCGCATGA TCGATCCCGA


 


501
AGAATTTACC GCCGCGCAGG CGAATATGTT TGCCGGATTC AATACCGTCC


 


551
ACAGCGAGCT TTTGGGCATA GGCGCGCTGA TTCTGCTCGT CAGCGCGGCG


 


601
GTCGTTTGGC GCGAACGCTA CCGCTTGGAC GTTTACCTTT TGGGGCGTGA


 


651
CCAAGCCGTC AATTTGGGCA TCAGCTACAC GCGCAACACC TTATGGATAC


 


701
TGCTTTGGAT TGCCGCATTG GTGGCGACGG CGACCGCCGT GGTCGGCCCC


 


751
GTAAGCTTTT TCGGGCTTCT CGCCGCCTCG CTTGCCAACC ACTTTTCCCC


 


801
GTCGGTCAAA CATTCCGTCC GCCTGCCGAT GACGGTTTGT ATCGGCGGCA


 


851
TCCTCTTGGT CGGCGGACAG ACCGTGTTCG AACACCTGCT CGGTATGCAG


 


901
GCAGTGTTGA GCGTAGTAGT AGAATTTGCC GGCGGACTCG TTTTCCTCTA


 


951
TCTCGTTTTA AAACACAAAA AATGA






This corresponds to the amino acid sequence <SEQ ID 1982; ORF 619>:










m619.pep




1
MPSEKNIGFM AGSSRPLWVA FALLLVSCVL FMTLNVKGDW DFVLQLRLTK


 


51
LAALLMVAYA VGVSTQLFQT LTNNPILTPS ILGFDSLYVF LQTLLVFTFG


 


101
GVGYASLPLT GKFGFELVVM MGGSLLLFYT LIKQGGRDLS RMILIGVIFG


 


151
ILFRSLSSLL SRMIDPEEFT AAQANMFAGF NTVHSELLGI GALILLVSAA


 


201
VVWRERYRLD VYLLGRDQAV NLGISYTRNT LWILLWIAAL VATATAVVGP


 


251
VSFFGLLAAS LANHFSPSVK HSVRLPMTVC IGGILLVGGQ TVFEHLLGMQ


 


301
AVLSVVVEFA GGLVFLYLVL KHKK*






m619/g619 95.1% identity in 324 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1983>:










a619.seq




1
ATGCCGTCTG AAAAAAATAT CGGTTTTATG GCAGGAAGCA GCCGTCCGTT



 


51
GTGGGTTGCC TTTGCGCTGT TGCTGGTTTC CTGCATCCTG TTTATGACGC


 


101
TCAACGTCAA AGGCGATTGG GATTTTGTTT TGCACCTGCG CCTGACCAAG


 


151
CTTGCCGCGC TGCTGATGGT CGCCTATGCG GTCGGCGTTT CGACCCAGCT


 


201
TTTTCAAACG CTGACCAACA ATCCGATTCT GACCCCTTCG ATTTTGGGTT


 


251
TCGATTCGCT GTATGTGTTT TTGCAGACCT TGCTGGTGTT TACGTTCGGC


 


301
GGCGTGGGCT ATGCTTCCCT GCCGTTGACG GGCAAATTCG GCTTTGAACT


 


351
GGTCGTTATG ATGGGCGGCT CGCTGCTGCT GTTTTACACG CTCATCAAAC


 


401
AGGGCGGGCG CGATTTGCCG CGTATGATTT TAATCGGCGT GATTTTCGGG


 


451
ATTTTGTTCC GCAGCCTGTC GTCGCTGCTT TCGCGCATGA TCGACCCCGA


 


501
AGAATTTACG GCGGCGCAGG CGAATATGTT TGCCGGATTC AATACCGTCC


 


551
ACAGCGAGCT TTTAGGCATA GGCGCGCTGA TTCTGCTCGT CAGCGCGGCG


 


601
GTCGTTTGGC GCGAACGCTA CCGCTTGGAC GTACACCTTT TGGGGCGCGA


 


651
CCAAGCCATA AATTTGGGCA TCAGCTACAC GCGCAACACC TTATGGATAC


 


701
TGCTTTGGAT TGCCGCGCTG GTGGCGACGG CGACCGCCGT TGTCGGCCCG


 


751
GTAAGCTTTT TCGGGCTTCT CGCCGCCTCG CTTGCCAACC ACTTTTCCCC


 


801
GTCGGTCAAA CATTCCGTCC GCCTGCCGAT GACGGTTTGT GTCGGCGGCA


 


851
TCCTCTTGGT CGGCGGACAG ACCGTATTCG AACACTTCTT GGGCATGAAG


 


901
GCGGTATTAA GCGTGGTGGT CGAATTTGCG GGCGGACTCG TTTTCCTCTA


 


951
TCTCGTTTTA AGACACAAAA AATGA






This corresponds to the amino acid sequence <SEQ ID 1984; ORF 619.a>:










a619.pep




1
MPSEKNIGFM AGSSRPLWVA FALLLVSCIL FMTLNVKGDW DFVLHLRLTK



 


51
LAALLMVAYA VGVSTQLFQT LTNNPILTPS ILGFDSLYVF LQTLLVFTFG


 


101
GVGYASLPLT GKFGFELVVM MGGSLLLFYT LIKQGGRDLP RMILIGVIFG


 


151
ILFRSLSSLL SRMIDPEEFT AAQANMFAGF NTVHSELLGI GALILLVSAA


 


201
VVWRERYRLD VHLLGRDQAI NLGISYTRNT LWILLWIAAL VATATAVVGP


 


251
VSFFGLLAAS LANHFSPSVK HSVRLPMTVC VGGILLVGGQ TVFEHFLGMK


 


301
AVLSVVVEFA GGLVFLYLVL RHKK*






m619/a619 97.2% identity in 324 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1985>:










g620.seq




1
ATGAAGAAAA CCCTGTTGGc AATTGTTGCC gtTTTCGCCT TAAGTGCCTG



 


51
CCGGCaggcg gaAGaggcac cgccgCCTTT ACCCCGGCAG AtTAGCGacc


 


101
gttcggtcgg aCACTAttgC Agtatgaacc tgaccgaaca caacggcccc


 


151
aaagcccaga tttttttgaa cGGCAAACCC GATCAGCCCG TTTGGTTCTC


 


201
CACCGTcaag cagatgttcg GCTATACCAA GCTGCCCGAA GAGCCCAAAG


 


251
GCATCCGCGT GATTTACGTT ACCGATATGG GCAATGTTAC CGATTGGACG


 


301
AATCCTAATG CCGACACGGA GTGGATAGAT GCGAAAAAAG CCTTTTACGT


 


351
CATCGACAGC GGCTTTATCG GCGGTATGGG CGCGGAAGAC GCGCTGCCGT


 


401
TCGGCAACAA GGAGCAGGCT GAAAAATTTG CAAAGGATAA AGGCGGCAAG


 


451
GTCGTCGGTT TTGACGATAT GCCCGATGCT TACATTTTCA AGTAA






This corresponds to the amino acid sequence <SEQ ID 1986; ORF 620.ng>:










g620.pep




1
MKKTLLAIVA VFALSACRQA EEAPPPLPRQ ISDRSVGHYC SMNLTEHNGP



 


51
KAQIFLNGKP DQPVWFSTVK QMFGYTKLPE EPKGIRVIYV TDMGNVTDWT


 


101
NPNADTEWID AKKAFYVIDS GFIGGMGAED ALPFGNKEQA EKFAKDKGGK


 


151
VVGFDDMPDA YIFK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1987>:










m620.seq




1
ATGAAAAAAA CCCTGTTGGC AATTGTTGCC GTTTCCGCCT TAAGTGCCTG



 


51
CCGGCAGGCG GAAGAGGGAC CGCCGCCTTT ACCCCGGCAG ATTAGCGACC


 


101
GTTCGGTCGG ACACTATTGC AGTATGAACC TGACCGAACA CAACGGCCCC


 


151
AAAGCCCAGA TTTTCTTGAA CGGCAAACCC GATCAGCCCG TTTGGTTCTC


 


201
CACCATCAAG CAGATGTTCG GCTATACCAA GCTGCCCGAA GAGCCTAAAG


 


251
GCATCCGCGT GATTTACGTT ACCGATATGG GCAATGTTAC CGATTGGACG


 


301
AATCCCAATG CCGACACGGA GTGGATGGAT GCGAAAAAAG CCTTTTACGT


 


351
CATCGACAGC GGCTTTATCG GCGGTATGGG TGCGGAAGAC GCGCTGCCGT


 


401
TCGGCAACAA AGAGCAGGCT GAGAAATTTG CAAAGGATAA AGGCGGTAAG


 


451
GTTGTCGGTT TCGACGATAT GCCTGATACC TATATTTTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 1988; ORF 620>:










m620.pep




1
MKKTLLAIVA VSALSACRQA EEGPPPLPRQ ISDRSVGHYC SMNLTEHNGP


 


51
KAQIFLNGKP DQPVWFSTIK QMFGYTKLPE EPKGIRVIYV TDMGNVTDWT


 


101
NPNADTEWMD AKKAFYVIDS GFIGGMGAED ALPFGNKEQA EKFAKDKGGK


 


151
VVGFDDMPDT YIFK*






m620/g620 97.0% identity in 164 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1989>:










a620.seq




1
ATGAAAAAAA CCCTGTTGGC AATTGTTGCC GTTTCCGCCT TAAGTGCCTG


 


51
CCGGCAGGCG GAAGAGGGAC CGCCGCCTTT ACCCCGGCAG ATTAGCGACC


 


101
GTTCGGTCGG ACACTATTGC AGTATGAACC TGACCGAACA CAACGGCCCC


 


151
AAAGCCCAGA TTTTCTTGAA CGGCAAACCC GATCAGCCCG TTTGGTTCTC


 


201
CACCATCAAG CAGATGTTCG GCTATACCAA GCTGCCCGAA GAGCCTAAAG


 


251
GCATCCGCGT GATTTACGTT ACCGATATGG GCAATGTTAC CGATTGGACG


 


301
AATCCCAATG CCGACACGGA GTGGATGGAT GCGAAAAAAG CCTTTTACGT


 


351
CATCGACAGC GGCTTTATCG GCGGTATGGG TGCGGAAGAC GCGCTGCCGT


 


401
TCGGCAACAA AGAGCAGGCT GAGAAATTTG CAAAGGATAA AGGCGGTAAG


 


451
GTTGTCGGTT TCGACGATAT GCCTGATACC TATATTTTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 1990; ORF 620.a>:










a620.pep




1
MKKTLLAIVA VSALSACRQA EEGPPPLPRQ ISDRSVGHYC SMNLTEHNGP


 


51
KAQIFLNGKP DQPVWFSTIK QMFGYTKLPE EPKGIRVIYV TDMGNVTDWT


 


101
NPNADTEWMD AKKAFYVIDS GFIGGMGAED ALPFGNKEQA EKFAKDKGGK


 


151
VVGFDDMPDT YIFK*






m620/a620 100.0% identity in 164 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1991>:










g622.seq




1
ATGCAactta ccgctgtcgg ACTCAATCAT CAAACCGCAC CTTTAAGCAT


 


51
ACGGGAAAag ctggCGTTTG CCGCCGCCGC CCTGCCAGAA gccgTccgCA


 


101
ATCTTGCCCG AAGCAATGCG GCAACGGAGG CGGTAATCCT TTCTACCTGC


 


151
AACCGCACCG AGCTTTACTG CGTCGGCGAT TCGGAAgaaa TCATCCGATG


 


201
GCTTGCCGAT TACCACAGTT TGCCGATTGA AGAAATCCGT CCGTATCTGT


 


251
ACACGCTGGA TATGCAGGAA ACCGTGCGCC ACGCCTTCCG CGTTGCCTGC


 


301
GGCTTGGATT CGATGGTTTT GGGCGAGCCG CAGATTTTGG GGCAGATTAA


 


351
AGATGCGGTG CGTGCGGCTC AAGAACAGGA AAGTATGGGG GCAAAACTCA


 


401
ATGCCCTGTT CCAAAAAACC TTTTCCGTTG CTAAAGAAGT CCGTACCGAT


 


451
ACCGCTGTCG GCGAAAATTC GGTTTCGATG GCTTCCGCGT CCGTCAAGTT


 


501
GGCGGAACAG ATTTTTCCCG ACATCGGCGA TTTGAACGTA TTGTTTATCG


 


551
GCGCAGGCGA AATGATTGAG CTGGTTGCCA CTTATTTTGC CGCCAAAAAT


 


601
CCCCGGCTGA TGACGGTTGC CAACCGGACG CTGGCGCGTG CACAGGAGTT


 


651
GTGCGACAAG CTCGGTGTTA ACGCCGAACC GTGCCTGCTG TCCGATCTGC


 


701
CTGCCATTCT GCACGATTAC GACGTGGTGG TTTCTTCAAC GGCGAGCCAG


 


751
CTTCCGATAG TCGGCAAAGG CATGGTCGAA CGCGCATTGA AACAGCGTCA


 


801
GAGTATGCCG TTGTTCATGC TTGACTTGGC CGTGCCGCGC GATATTGAAG


 


851
CGGAAGTCGG CGATTTGAAC GATGCGTATC TTTATACGGT GGACGATATG


 


901
GTCAACATCG TCCAAAGCGg caaggaggca aggcagaaag ccgccgcCgc


 


951
cgccgaaacg ctggTGTCCG AAAAGGTTGC CGAATTTGTC AGGCAGCAGC


 


1001
AGGGCAGGCA GagcgttcCG CTGATTAAGG CCTTGCGGGA CGAGGGCGAG


 


1051
AAAGCGCGCA AGCAGGTGTT GGAAAATGCG ATGAAACAGC TTGCCAAAGG


 


1101
CGcaaCGGCG GAAGaggttt TGgaacggct gtccgtcCAA CTGACCAACA


 


1151
AGCTGCTGCA TTCGCCAACT CAAACCTTGA ATAAGGCGGG GGAAGAAGAT


 


1201
AAAGatttGG TTCATGCCgt cGCGCAGATt tatcatttGG ACAAATAA






This corresponds to the amino acid sequence <SEQ ID 1992; ORF 622.ng>:










g622.pep




1
MQLTAVGLNH QTAPLSIREK LAFAAAALPE AVRNLARSNA ATEAVILSTC


 


51
NRTELYCVGD SEEIIRWLAD YHSLPIEEIR PYLYTLDMQE TVRHAFRVAC


 


101
GLDSMVLGEP QILGQIKDAV RAAQEQESMG AKLNALFQKT FSVAKEVRTD


 


151
TAVGENSVSM ASASVKLAEQ IFPDIGDLNV LFIGAGEMIE LVATYFAAKN


 


201
PRLMTVANRT LARAQELCDK LGVNAEPCLL SDLPAILHDY DVVVSSTASQ


 


251
LPIVGKGMVE RALKQRQSMP LFMLDLAVPR DIEAEVGDLN DAYLYTVDDM


 


301
VNIVQSGKEA RQKAAAAAET LVSEKVAEFV RQQQGRQSVP LIKALRDEGE


 


351
KARKQVLENA MKQLAKGATA EEVLERLSVQ LTNKLLHSPT QTLNKAGEED


 


401
KDLVHAVAQI YHLDK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1993>:










m622.seq




1
ATGCAACTTA CCGCTGTCGG ACTCAATCAT CAAACCGCAC CTTTAAGCAT


 


51
ACGGGAAAAG CTGGCGTTTG CCGCCGCCGC CCTGCCTAAA GCCGTCCGCA


 


101
ATCTTGCCCG AAGCAATGCG GCAACGGAGG CGGTAATCCT TTCTACCTGC


 


151
AACCGCACCG AGCTTTACTG CGTCGGTGAT TCGGAAGAAA TCATCCGATG


 


201
GCTTGCCGAT TACCACAGTT TGCCGATTGA AGAAATCCGT CCGTATCTGT


 


251
ACGCGCTGGA TATGCAGGAG ACTGTGCGCC ATGCTTTCCG CGTCGCCTGC


 


301
GGGCTGGATT CGATGGTGTT GGGCGAGCCG CAGATTTTAG GACAGATTAA


 


351
GGATGCCGTT AGGGTTGCTC AAGAGCAGGA AAGTATGGGT AAGAAACTCA


 


401
ATGCCCTGTT CCAAAAAACC TTTTCCGTTG CTAAAGAGGT CCGTACCGAT


 


451
ACTGCCGTCG GCGAAAACTC GGTTTCCATG GCTTCCGCTT CCGTCAAATT


 


501
GGCGGAACAG ATTTTTCCCG ACATCGGCGA TTTGAATGTC TTGTTTATCG


 


551
GCGCAGGCGA AATGATTGAG CTGGTTGCCA CTTATTTTGC CGCCAAAAGT


 


601
CCCCGGCTGA TGACGGTTGC CAACCGGACG CTGGCGCGTG CACAGGAGTT


 


651
GTGCGACAAG CTCGGTGTCA ACGCCGAACC GTGCCTGCTG TCCGATCTGC


 


701
CTGCCATTCT GCACGATTAC GACGTAGTGG TTTCTTCAAC GGCAAGCCAG


 


751
TTGCCCATTG TCGGCAAAGG CATGGTGGAG CGTGCATTGA AACAAAGGCA


 


801
GAGTATGCCG TTGTTCATGC TTGATTTGGC AGTGCCGCGT GACATTGAAG


 


851
CGGAAGTCGG CGATTTGAAT GATGCCTATC TTTATACGGT GGACGATATG


 


901
GTCAATATCG TCCAAAGCGG CAAGGAGGCA AGGCAGAAGG CCGCCGCCGC


 


951
CGCCGAAACG CTGGTGTCCG AGAAAGTTGC CGAATTTGTC AGGCAGCAGC


 


1001
AGGGCAGGCA GAGTGTCCCC TTGATTAAGG CGTTGCGGGA CGAGGGCGAG


 


1051
AAAGCGCGCA AACAGGTGTT GGAAAATGCC ATGAAACAGC TTGCCAAAGG


 


1101
CGCAACGGCA GAAGAGGTTT TGGAACGGCT GTCCGTCCAA CTGACCAACA


 


1151
AGCTGCTGCA TTCGCCGACC CAAACCTTGA ATAAGGCGGG GGAAGAAGAT


 


1201
AAAGATTTGG TTCATGCCGT CGCGCAGATT TATCATTTGG ACAAATAA






This corresponds to the amino acid sequence <SEQ ID 1994; ORF 622>:










m622.pep




1
MQLTAVGLNH QTAPLSIREK LAFAAAALPK AVRNLARSNA ATEAVILSTC


 


51
NRTELYCVGD SEEIIRWLAD YHSLPIEEIR PYLYALDMQE TVRHAFRVAC


 


101
GLDSMVLGEP QILGQIKDAV RVAQEQESMG KKLNALFQKT FSVAKEVRTD


 


151
TAVGENSVSM ASASVKLAEQ IFPDIGDLNV LFIGAGEMIE LVATYFAAKS


 


201
PRLMTVANRT LARAQELCDK LGVNAEPCLL SDLPAILHDY DVVVSSTASQ


 


251
LPIVGKGMVE RALKQRQSMP LFMLDLAVPR DIEAEVGDLN DAYLYTVDDM


 


301
VNIVQSGKEA RQKAAAAAET LVSEKVAEFV RQQQGRQSVP LIKALRDEGE


 


351
KARKQVLENA MKQLAKGATA EEVLERLSVQ LTNKLLHSPT QTLNKAGEED


 


401
KDLVHAVAQI YHLDK*






m622/g622 98.8% identity in 415 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1995>:










a622.seq




1
ATGCAACTTA CCGCTGTCGG ACTCAATCAT CAAACCGCAC CTTTAAGCAT


 


51
ACGGGAAAAG CTGGCGTTTG CCGCGGCCTG CCTGCCCGAA GCCGTCCGCA


 


101
ATCTTGCCCG AAGCAATGCG GCAACGGAGG CGGTAATCCT TTCTACCTGC


 


151
AACCGTACCG AGCTTTACTG TGTAGGTGAT TCGGAAGAAA TCATCCGTTG


 


201
GCTCGCAGAC TATCACAGCC TTCCCATAGA AGAAATCAGC CCCTACCTTT


 


251
ATACTTTGGG GATGCAGGAG ACTGTGCGCC ATGCTTTCCG CGTCGCCTGC


 


301
GGCTTGGATT CGATGGTGTT GGGCGAGCCG CAGATTTTAG GACAGATTAA


 


351
GGATGCGGTC AGGGTTGCTC AAGAGCAGGA AAGTATGGGT AAGAAACTCA


 


401
ATGCCCTGTT CCAAAAAACC TTTTCTGTTG CTAAAGAGGT CCGTACCGAT


 


451
ACTGCCGTCG GCGAAAACTC GGTTTCCATG GCTTCCGCTT CCGTCAAGTT


 


501
GGCAGAGCAG ATTTTCCCCG ACATCGGCGA TTTGAATGTC TTGTTTATCG


 


551
GTGCGGGTGA GATGATTGAG CTGGTTGCCA CTTATTTTGC CGCCAAAAGT


 


601
CCCCGGCTGA TGACGGTTGC CAACCGGACG CTGGCGCGTG CACAGGAGTT


 


651
GTGCGACAAG CTCGGTGTCA ACGCCGAACC GTGCCTGCTG TCCGATCTGC


 


701
CTGCCATTTT GCATGAGTAC GACGTGGTGG TTTCTTCAAC GGCAAGCCAG


 


751
TTGCCCATTG TCGGCAAAGG TATGGTGGAG CGCGCATTGA AACAAAGGCA


 


801
GAGTATGCCG TTGTTTATGC TTGACTTGGC CGTGCCGCGA GACATTGAGG


 


851
CGGAAGTCGG AGATTTGAAC GATGCCTATC TTTATACGGT GGACGATATG


 


901
GTCAATATCG TCCAAAGCGG CAAGGAGGCA AGGCAGAAGG CCGCCGCCGC


 


951
CGCCGAAACG CTGGTGTCCG AGAAGGTTGC CGAATTTGTC AGGCAGCAGC


 


1001
AGGGCAGGCA GAGTGTCCCG TTAATCAGGG CATTGAGGGA TGAGGGAGAG


 


1051
AAAGCGCGCA AACAGGTCTT GGAAAATGCG ATGAAACAGC TTGCCAAAGG


 


1101
CGCAACGGCA GAAGAGGTTT TGGAAAGGCT GTCGATCCAA CTGACCAACA


 


1151
AGCTGCTGCA TTCGCCGACC CAAACCTTGA ATAAGGCGGG GGAAGAAGAT


 


1201
AAAGATTTGG TTCACGCCGT CGCGCAGATT TATCATTTGG ACAAATAA






This corresponds to the amino acid sequence <SEQ ID 1996; ORF 622.a>:










a622.pep




1
MQLTAVGLNH QTAPLSIREK LAFAAACLPE AVRNLARSNA ATEAVILSTC


 


51
NRTELYCVGD SEEIIRWLAD YHSLPIEEIS PYLYTLGMQE TVRHAFRVAC


 


101
GLDSMVLGEP QILGQIKDAV RVAQEQESMG KKLNALFQKT FSVAKEVRTD


 


151
TAVGENSVSM ASASVKLAEQ IFPDIGDLNV LFIGAGEMIE LVATYFAAKS


 


201
PRLMTVANRT LARAQELCDK LGVNAEPCLL SDLPAILHEY DVVVSSTASQ


 


251
LPIVGKGMVE RALKQRQSMP LFMLDLAVPR DIEAEVGDLN DAYLYTVDDM


 


301
VNIVQSGKEA RQKAAAAAET LVSEKVAEFV RQQQGRQSVP LIRALRDEGE


 


351
KARKQVLENA MKQLAKGATA EEVLERLSIQ LTNKLLHSPT QTLNKAGEED


 


401
KDLVHAVAQI YHLDK*






m622/a622 98.1% identity in 415 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 1997>:










g624.seq




1
ATGATCCGTT ATCTTTTAAT TGCCTGCGGC GGCATCTCCC TGCTGTTGGG


 


51
GATAATCGGC ATTTTTTTGC CGCTGTTGCC GACCACGCCG TTCGTACTAC


 


101
TCTCCGCCGC CTGCTGGGCA AAGGCAtccc cgcgcTTTCa ccgCTGGCTG


 


151
CACcgGCacc gCTATTTCGG CCCGATGGTT CATAACTGGG AACAAAACGG


 


201
CGCAGTGCCG CGCAAAGCCA AGATTTTCGC CATCAGCATG AtaaccgcAt


 


251
cctgcctcat gatctTTtgg CattTTCccc aacnctggtg ggtcGGGGCG


 


301
GTTTCATCGG TTTTTTGTTC CCTTGTcacC ATacggatgt gGcacAGacC


 


351
cgaatCTTGA






This corresponds to the amino acid sequence <SEQ ID 1998; ORF 624.ng>:










g624.pep




1
MIRYLLIACG GISLLLGIIG IFLPLLPTTP FVLLSAACWA KASPRFHRWL


 


51
HRHRYFGPMV HNWEQNGAVP RKAKIFAISM ITASCLMIFW HFPQXWWVGA


 


101
VSSVFCSLVT IRMWHRPES*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 1999>:










m624.seq




1
ATGATACGTT ATCTTTTAAT TGCCTGCGGC TGCATTTCCC TACTGTTGGG


 


51
TATCATCGGC ATTTTTTTGC CGCTGTTGCC GACCACGCCG TTCGTACTGC


 


101
TCTCCGCCGC CTGCTGGGCA AAGGCATCCC CGCGCTTTTA CCGCTGGCTG


 


151
CACCGGCACC GCTATTTCGG CCCGATGGTT CATAACTGGG AACAAAACGG


 


201
CGCAGTGCCG CGCAAAGCCA AAATATTCGC CATCAGTATG ATGACCGCAT


 


251
CCTGCCTGAT AATGTTTTGG CAGTTTCCCC AACGCTGGTG GGTCGGGGCG


 


301
GTTTCATCGG TTTTTTGTTC CCTTGTCGCC ATATGGATGT GGCGCAGGCC


 


351
CGAATCTTGA






This corresponds to the amino acid sequence <SEQ ID 2000; ORF 624>:










m624.pep




1
MIRYLLIACG CISLLLGIIG IFLPLLPTTP FVLLSAACWA KASPRFYRWL


 


51
HRHRYFGPMV HNWEQNGAVP RKAKIFAISM MTASCLIMFW QFPQRWWVGA


 


101
VSSVFCSLVA IWMWRRPES*






m624/g624 91.6% identity in 119 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2001>:










a624.seq




1
ATGATACGTT ATCTTTTAAT TGCCTGCGGC TGCATTTCCC TGCTGTTGGG


 


51
TATCATCGGC ATTTTTTTGC CGCTGTTGCC GACCACGCCG TTCGTACTGC


 


101
TCTCCGCCGC CTGCTGGGCA AAGGCATCCC CGCGCTTTCA CCGCTGGCTG


 


151
CACCGGCACC GCTATTTCGG TCCGATGGTT CATAACTGGG AACAAAACGG


 


201
CGCAGTGCCG CGCAAAGCCA AAATATTCGC CATCAGTATG ATGACCGCAT


 


251
CCTGCCTGAT AATGTTTTGG CAGTTTCCCC AACGCTGGTG GGTCGGGGCG


 


301
GTTTCATCGG TTTTTTGTTC CCTTGTCGCC ATATGGATGT GGCGCAGGCC


 


351
CGAATCTTGA






This corresponds to the amino acid sequence <SEQ ID 2002; ORF 624.a>:










a624.pep




1
MIRYLLIACG CISLLLGIIG IFLPLLPTTP FVLLSAACWA KASPRFHRWL


 


51
HRHRYFGPMV HNWEQNGAVP RKAKIFAISM MTASCLIMFW QFPQRWWVGA


 


101
VSSVFCSLVA IWMWRRPES*






m624/a624 99.2% identity in 119 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2003>:










a625.seq




1
ATGTTTGCAA CCAGGAAAAT GAAGAAGATG ACGATGTGCA CGCGGCGGGT


 


51
ACGGTTTTGG TTGGCTTTCA GCAGCGGACG AATCATCAGC ATTGCTGCGC


 


101
CGGTCGTTCC CATGATAGAG GCAAGTGCCG TACCGACGGC AAGCAGGGCG


 


151
GTGTTGAGCT TGGGTGTGCC GTTCAAGTCG CCCCAAACCA AAATGCCGCC


 


201
TGAAATGGTG TACAGGGCAA GCAGCAGCAG GATGAAAGGG ATGTATTCTT


 


251
CAACGAGTGC GTGTGCGACG GTATGGATAC CGGCGGACGC GCCAAAAACC


 


301
AAACTGAACG GGATGAGGAA GAGCAATGTC CAAAAGGCGG TAATTTTGCC


 


351
GTAA






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2004>:










g625.seq




1
atGTTTGCAA CCAGGAAAAT GAAGAAGATG ACGATGTGCA CGCGGCGGGT


 


51
ACGGtcTTGG TTGGCTTTCA GCAGCGGACG AATCATCAGC AttgCCGCGC


 


101
CGGtcgttcC CATGATAGAG GCAAGTGCCG TACCGACGGC AAGCAGGGCG


 


151
GTGTTGAGCT TGGGTGTGCC GTTCAAGTCG CCCCAAACCA AAATGCCGCC


 


201
TGAAATGGTG TACAGGGCAA GCAGCAGCAG GATGAAGGGG ATATATTCTT


 


251
CAACGAGTGC GTGTGCGACG GTATGGATAC CGGCGGACGC GCCAAAAACC


 


301
AAACTGAACG GGATGAGGAA GAGCAATGTC CAAAAGGCGG TGATTTTGCc


 


351
gtAA






This corresponds to the amino acid sequence <SEQ ID 2005; ORF 625.ng>:










g625.pep




1
MFATRKMKKM TMCTRRVRSW LAFSSGRIIS IAAPVVPMIE ASAVPTASRA


 


51
VLSLGVPFKS PQTKMPPEMV YRASSSRMKG IYSSTSACAT VWIPADAPKT


 


101
KLNGMRKSNV QKAVILP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2006>:










m625.seq




1
ATGTTTGCAA CCAGGAAAAT GAAGAAGATG ACGATGTGCA CGCGGCGGGT


 


51
ACGGTTTTGG TTGGCTTTCA GCAGCGGACG AATCATCAGC ATTGCTGCGC


 


101
CGGTCGTTCC CATGATAGAG GCAAGTGCCG TACCGACGGC AAGCAGGGCG


 


151
GTGTTGAGCT TGGGTGTGCC GTTCAAGTCG CCCCAAACCA AAATGCCGCC


 


201
TGAAATGGTG TACAGGGCAA GCAGCAGCAG GATGAAAGGG ATGTATTCTT


 


251
CAACGAGTGC GTGTGCGACG GTATGGATAC CGGCGGACGC GCCAAAAACC


 


301
AAACTGAACG GGATGAGGAA GAGCAATGTC CAAAAGGCGG TAATTTTGCC


 


351
GTAA






This corresponds to the amino acid sequence <SEQ ID 2007; ORF 625>:










m625.pep




1
MFATRKMKKM TMCTRRVRFW LAFSSGRIIS IAAPVVPMIE ASAVPTASRA


 


51
VLSLGVPFKS PQTKMPPEMV YRASSSRMKG MYSSTSACAT VWIPADAPKT


 


101
KLNGMRKSNV QKAVILP*






m625/g625 98.3% identity in 117 aa overlap





This corresponds to the amino acid sequence <SEQ ID 2008; ORF 625.a>:










a625.pep




1
MFATRKMKKM TMCTRRVRFW LAFSSGRIIS IAAPVVPMIE ASAVPTASRA


 


51
VLSLGVPFKS PQTKMPPEMV YRASSSRMKG MYSSTSACAT VWIPADAPKT


 


101
KLNGMRKSNV QKAVILP*






m625/a625 100.0% identity in 117 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2009>:










g627.seq




1
ATGTCCGGCC TTTGGAAACC CGAACACCCG GGATTTGAAA TCCTCGGCAG


 


51
CCGTTACGCC CTGCAAAACC TTGTCCGCGA TGTCATCCTG ATTACATTGA


 


101
CCGCCGTATC TATGGCAATC ACGCCCAAAC AAGTCCGCGC AGGCAACGAA


 


151
TTCAACTTTG AACCCATCGC CGAAGTGGGC AAACTCTTCC TCGGCATCTT


 


201
CATCACCATC TTCCCCGTCC TGAGCATTCT GAAAGCAGGC GAGGCAGGCG


 


251
CGCTGGGCGG GGTGGTATCG CTGGTTCACG ATACGGCAGG TCATCCGATT


 


301
AATACGATGT ATTTCTGGAT GAGCGGCATA TTGTCGGCAT TCTTGGATAA


 


351
CGCGCCCACT TATCTCGTGT TTTTCAATAT GGCGGGCGGC GATGCCCAAG


 


401
CCTTAATGAC GGGTCCCCTG TTTCATTcgc TGCTGGCGGT TTCTAtgggT


 


451
tCGGTATTCA TGGGCGCACT GaccTACATc gGCAAcgcac cgaactTCAT


 


501
GGTcaaggcc aTTGCCGaaC agcgcgGCgt accgaTGCcg actTTCTTcc


 


551
ggtaTAtgat gtggtcggtc gcCTTCCTGa caCCCGTCTT CAtcgTACAT


 


601
ACCCTcgtCT TTTTcgTTtt cAAACTACTg taa






This corresponds to the amino acid sequence <SEQ ID 2010; ORF 627.ng>:










g627.pep




1
MSGLWKPEHP GFEILGSRYA LQNLVRDVIL ITLTAVSMAI TPKQVRAGNE


 


51
FNFEPIAEVG KLFLGIFITI FPVLSILKAG EAGALGGVVS LVHDTAGHPI


 


101
NTMYFWMSGI LSAFLDNAPT YLVFFNMAGG DAQALMTGPL FHSLLAVSMG


 


151
SVFMGALTYI GNAPNFMVKA IAEQRGVPMP TFFRYMMWSV AFLTPVFIVH


 


201
TLVFFVFKLL *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2011>:










m627.seq




1
ATGTCCGGCC TTTGGAAACC CGAACACCCG GGATTTGAAA TCCTCGGCAG


 


51
CCGTTACGCC CTGCAAAACC TCGTCCGCGA TGTCATCCTG ATTGCATTGA


 


101
CCGCCGTATC TATGGCAATC ACGCCCAAAC AAGTCCGCGC AGGCAACGAA


 


151
TTCAACTTTG AACCCATCGC CGAAGTGGGC AAACTCTTCC TCGGCATCTT


 


201
CATCACCATC TTTCCCGTCC TGAGCATTCT GAAAGCAGGC GAGGCAGGCG


 


251
CGCTGGGCGG GGTGGTATCG CTGGTTCACG ATACGGCAGG TCATCCGATT


 


301
AATGTGATGT ATTTTTGGAT GAGCGGCATA TTGTCGGCAT TCTTGGATAA


 


351
CGCGCCCACT TATCTCGTTT TTTTCAATAT GGCGGGCGGC GATGCCCAAG


 


401
CCTTGATGAC GGGTACCCTG TTTCATTCGC TGCTGGCGGT TTCTATGGGT


 


451
TCGGTATTCA TGGGCGCACT GACCTACATC GGCAACGCAC CGAACTTCAT


 


501
GGTCAAGGCC ATTGCCGAAC AGCGCGGCGT ACCGATGCCG ACTTTCTTCG


 


551
GCTATATGAT GTGGTCGGTC GCCTTCCTGA CACCCGTCTT CATCGTACAT


 


601
ACCCTTATCT TTTTCGTTTT CAAACTGCTG TAA






This corresponds to the amino acid sequence <SEQ ID 2012; ORF 627>:










m627.pep




1
MSGLWKPEHP GFEILGSRYA LQNLVRDVIL IALTAVSMAI TPKQVRAGNE


 


51
FNFEPIAEVG KLFLGIFITI FPVLSILKAG EAGALGGVVS LVHDTAGHPI


 


101
NVMYFWMSGI LSAFLDNAPT YLVFFNMAGG DAQALMTGTL FHSLLAVSMG


 


151
SVFMGALTYI GNAPNFMVKA IAEQRGVPMP TFFGYMMWSV AFLTPVFIVH


 


201
TLIFFVFKLL *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m627/g627 97.6% identity in 210 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2013>:










a627.seq




1
ATGTCCGGCC TTTGGAAACC CGAACACCCG GGATTTGAAA TCCTCGGCAG


 


51
CCGTTACGCC CTGCAAAACC TCGTCCGCGA TGTCATCCTG ATTGCATTGA


 


101
CCGCCGTATC TATGGCAATC ACGCCCAAAC AAGTCCGCGC AGGCAACGAA


 


151
TTCAACTTTG AACCCATCGC CGAAGTGGGC AAACTCTTCC TCGGCATCTT


 


201
CATCACCATC TTTCCCGTCC TGAGCATTCT GAAAGCAGGC GAGGCAGGCG


 


251
CGCTGGGCGG GGTGGTATCG CTGGTTCACG ATACGGCAGG TCATCCGATT


 


301
AATGTGATGT ATTTTTGGAT GAGCGGCATA TTGTCGGCAT TCTTGGATAA


 


351
CGCGCCCACT TATCTCGTTT TTTTCAATAT GGCGGGCGGC GATGCCCAAG


 


401
CCTTGATGAC GGGTTCCCTG TTTCATTCGC TGCTGGCGGT TTCTATGGGT


 


451
TCGGTATTCA TGGGCGCACT GACCTACATC GGCAACGCAC CGAACTTCAT


 


501
GGTCAAGGCC ATTGCCGAAC AGCGCGGCGT ACCGATGCCG ACTTTCTTCG


 


551
GCTATATGAT GTGGTCGGTC GCCTTCCTGA CACCCGTCTT CATCGTACAT


 


601
ACCCTTATCT TTTTCGTTTT CAAACTGCTG TAA






This corresponds to the amino acid sequence <SEQ ID 2014; ORF 627.a>:










a627.pep




1
MSGLWKPEHP GFEILGSRYA LQNLVRDVIL IALTAVSMAI TPKQVRAGNE


 


51
FNFEPIAEVG KLFLGIFITI FPVLSILKAG EAGALGGVVS LVHDTAGHPI


 


101
NVMYFWMSGI LSAFLDNAPT YLVFFNMAGG DAQALMTGSL FHSLLAVSMG


 


151
SVFMGALTYI GNAPNFMVKA IAEQRGVPMP TFFGYMMWSV AFLTPVFIVH


 


201
TLIFFVFKLL *






m627/a627 99.5% identity in 210 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2015>:










g628.seq




1
ATGTGCGTGC CACTCAAGCC GGCAGGATGC GGGCCGCCAA ATTCATGTGT


 


51
TTCGATATTG GCAGCATTTT CAGACGGCAC GTCTGCGCCT GCTGCTTTAC


 


101
ACACATGGAT TTTACGTTCG GTCAGGCGGC TCAATACCAA CAGGCCGCGT


 


151
TTGAAGTCTT CGGCGGCTTC TTTGATGATG ACCGTAGGGT CGGCAGCCAG


 


201
CGGATTGGTG TCCATCGCAT TGACGAAGAT GGCGAACGGC TCGGCATCTA


 


251
CGGCAGGGAT TTTGCTGAAC GGACGGGTGC GAAGCGCAGT CCATAAGCCT


 


301
GATTGAATCA GGTTGCGGCG CACTTTTTCG CTGCTCAATT TTGCCAGCGC


 


351
TTCAGGTacg TAG






This corresponds to the amino acid sequence <SEQ ID 2016; ORF 628.ng>:










g628.pep




1
MCVPLKPAGC GPPNSCVSIL AAFSDGTSAP AALHTWILRS VRRLNTNRPR


 


51
LKSSAASLMM TVGSAASGLV SIALTKMANG SASTAGILLN GRVRSAVHKP


 


101
D*IRLRRTFS LLNFASASGT *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2017>:










m628.seq




1
ATGTGCGTGC CACTCAAACC GGCAGGATGC GGGCCGCCGA ATTCATGTGT


 


51
TTCGATGTTG GCAGCATTTT CAGACGGCAC GTCTGCGCCA GCTGCCTTAC


 


101
AAACATGGAT TTTGCGTTCG GTCAAACGGC TCAATACCAA CAGGCCGCGT


 


151
TTGAAATCCT CGGCGGCTTC TTTGATAATG ACCGTAGGGT CGGCAGCCAG


 


201
CGGATTGGTG TCCATCGCAT TGACGAAGAT GGCGAACGGC TCGGCATCGA


 


251
CGGCAGGAAT TTTGCTGAAC GGACGGGTGC GCAGCGCAGT CCACAAACCG


 


301
GATTGGATCA GGTTGCGGCG CACTTCTTCG CCGCTTAAGT TTGCCAGCGC


 


351
TTCAGGTGCG TAG






This corresponds to the amino acid sequence <SEQ ID 2018; ORF 628>:










m628.pep




1
MCVPLKPAGC GPPNSCVSML AAFSDGTSAP AALQTWILRS VKRLNTNRPR


 


51
LKSSAASLIM TVGSAASGLV SIALTKMANG SASTAGILLN GRVRSAVHKP


 


101
DWIRLRRTSS PLKFASASGA *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m628/g628 93.3% identity in 119 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2019>:










a628.seq




1
ATGTGCGTGC CACTCAAACC GGCCGGATGC GGGCCGCCGA ATTCATGTGT


 


51
TTCGATGTTG GCAGCATTTT CAGACGGCAC GTCTGCGCCA GCTGCCTTAC


 


101
ACACATGGAT TTTACGCTCG GTCAAACGGC TCAATACCAG CAAACCTCGT


 


151
CTGAAATCCT CGGCGGCTTC TTTGATCACA ACCACAGGGT CTGCCGCCAG


 


201
CGGATTGGTG TCCATCGCAT TGACGAAGAT GGCGAACGGC TCGGCATCGA


 


251
CGGCAGGGAT TTTGCTGAAC GGACGGGTAC GCAGCGCAGT CCACAAACCG


 


301
GATTGGATCA GATTGCGGCG CACTTCTTCG CCGCTTAAGT TTGCCAACGC


 


351
TTCGGGCGCG TAG






This corresponds to the amino acid sequence <SEQ ID 2020; ORF 628.a>:










a628.pep




1
MCVPLKPAGC GPPNSCVSML AAFSDGTSAP AALHTWILRS VKRLNTSKPR


 


51
LKSSAASLIT TTGSAASGLV SIALTKMANG SASTAGILLN GRVRSAVHKP


 


101
DWIRLRRTSS PLKFANASGA *






m628/a628 95.0% identity in 120 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2021>:










g629.seq




1
ATGACTGCca aacCTTTTTC CCTCAACCTG GCcaaCCTCC TGCTGCCggc


 


51
ggtatTGTTT GCCGTCAGcc tGtcggTCGG cattgccgaT TTCCGCTGGT


 


101
CGGATGTGTT TTCGCTGTCC GACAGCCAGC AAGTGATGTT CATCAGCCGC


 


151
CTGCCGCGCA CGTTTGcgaT TGTGTTGACG GGCgcgtcga tagcgGtggc


 


201
gGGGAtgatt atgcagATTC TGATGCGCAA CcgtTTTGTC GAGCCTtcta


 


251
tggcgGGTGC GGGCCAAAGt gcgGCTTTGG GTttgcttct gAtgtccctg


 


301
ctgctgcctg CcgcGccgct gccggtcaAA ATGTCGGtag Ccgccgttgc


 


351
CGCGCTGATC GGGATGTTGG tctTtatgct gctaatccgC Cgcctgccac


 


401
cgacggcgca gctgatgGTg ccgCTGGTGG Gg.ttATTTT CGGCGGCGTG


 


451
GttgaGGCGG TGGCGACGTT TGTCGCGTAT GAGTTTGAGA TGCTGCAAAT


 


501
GTTGGGCGTG TGGCAGCAGG GCGACTTTTC AAGCGTGCTG CTGGGGCGGT


 


551
ACGAGCTGCT TTGGATTACG GGCGGTTTGG CGGTGTTTGC CTACCTGATT


 


601
GCCGACCGGC TGACGATTTT GGGGCTGGGC GAGACGGTGA GCGTGAATTT


 


651
GGGTTTGAAC CGGACGGCGG TGTTGTGGTC GGGTTTGATT ATTGTGGCAC


 


701
TGATTACATC GCTGGTCATT GTAACGGTCG GCAATATTCC GTTTATCGGG


 


751
CTGGTCGTGC CGAATATCGT CAGCCGCCTG ATGGGCGACA GGCTGCGCCA


 


801
AAGCCTGCCT GCGGTCGCCC TCTTGGGCGC GTCTTTGGTT TTATTGTGCG


 


851
ACATTATCGG ACGCATGATT GTGTTTCCGT TTGAAATTCC GGTCTCCACG


 


901
GTTTTTGGTG TGTTGGGTAC GGCTTTGTTT TTGTGGCTTT TGTTGAGGAA


 


951
ACCCGCCTAT GCCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 2022; ORF 629.ng>:










g629.pep




1
MTAKPFSLNL ANLLLPAVLF AVSLSVGIAD FRWSDVFSLS DSQQVMFISR


 


51
LPRTFAIVLT GASIAVAGMI MQILMRNRFV EPSMAGAGQS AALGLLLMSL


 


101
LLPAAPLPVK MSVAAVAALI GMLVFMLLIR RLPPTAQLMV PLVGXIFGGV


 


151
VEAVATFVAY EFEMLQMLGV WQQGDFSSVL LGRYELLWIT GGLAVFAYLI


 


201
ADRLTILGLG ETVSVNLGLN RTAVLWSGLI IVALITSLVI VTVGNIPFIG


 


251
LVVPNIVSRL MGDRLRQSLP AVALLGASLV LLCDIIGRMI VFPFEIPVST


 


301
VFGVLGTALF LWLLLRKPAY AV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2023>:










m629.seq




1
ATGACTGCCA AACCTTTTTC CCTCAACCTG ACCAACCTGC TGCTGCTGGC


 


51
GGTGTTGTTT GCCGTCAGCC TGTCGGTGGG CGTTGCCGAT TTCCGCTGGT


 


101
CTGATGTGTT TTCACTGTCC GACAGCCAGC AGGTCATGTT CATCAGCCGC


 


151
CTGCCGCGCA CGTTTGCGAT TGTGCTGACG GGCGCGTCGA TGGCGGTGGC


 


201
CGGCATGATT ATGCAGATTT TGATGCGCAA CCGTTTTGTC GAACCGTCGA


 


251
TGGTGGGCGC AAGCCAAAGC GCGGCTTTAG GTTTGCTGCT GATGACCCTG


 


301
CTGCTGCCGG CCGCGCCGCT GCCGGCGAAA ATGTCGGTTG CCGCCGTTGC


 


351
CGCGCTGATC GGGATGTTGG TCTTTATGCT GCTGATCCGC CGCCTGCCGC


 


401
CGACCGCGCA ACTGATGGTG CCTTTGGTCG GGATTATTTT CGGCGGTGTG


 


451
ATTGAGGCGG TAGCCACCTT TATCGCGTAT GAAAACGAAA TGCTGCAAAT


 


501
GCTCGGCGTG TGGCAGCAGG GCGATTTTTC GAGCGTGCTG CTGGGGCGGT


 


551
ACGAGCTGCT TTGGATTACG GGCGGTTTGG CGGTGTTTGC CTATCTGATT


 


601
GCCGACCGGC TGACGATTTT GGGGCTGGGC GAAACGGTAA GCGTGAATTT


 


651
GGGTTTGAAC CGGACGGCGG TGTTGTGGTC GGGTTTGATT ATTGTGGCTT


 


701
TGATTACGTC GCTGGTTATC GTTACGGTCG GCAATATTCC GTTTATCGGG


 


751
CTGGTCGTGC CGAACATCAT CAGCCGCCTG ATGGGCGACA GGTTGCGCCA


 


801
AAGCCTGCCT GCGGTGGCCT TGCTGGGCGC ATCTTTGGTG TTGCTGTGCG


 


851
ACATTATCGG ACGCGTGATT GTGTTTCCGT TTGAAATTCC GGTCTCTACG


 


901
GTTTTTGGTG TATTGGGTAC GGCTTTGTTT TTGTGGCTTT TGTTGAGGAA


 


951
ACCCGCCTAT GCCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 2024; ORF 629>:










m629.pep




1
MTAKPFSLNL TNLLLLAVLF AVSLSVGVAD FRWSDVFSLS DSQQVMFISR


 


51
LPRTFAIVLT GASMAVAGMI MQILMRNRFV EPSMVGASQS AALGLLLMTL


 


101
LLPAAPLPAK MSVAAVAALI GMLVFMLLIR RLPPTAQLMV PLVGIIFGGV


 


151
IEAVATFIAY ENEMLQMLGV WQQGDFSSVL LGRYELLWIT GGLAVFAYLI


 


201
ADRLTILGLG ETVSVNLGLN RTAVLWSGLI IVALITSLVI VTVGNIPFIG


 


251
LVVPNIISRL MGDRLRQSLP AVALLGASLV LLCDIIGRVI VFPFEIPVST


 


301
VFGVLGTALF LWLLLRKPAY AV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m629/g629 95.7% identity in 322 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2025>:










a629.seq




1
ATGACTGCCA AACCTTTTTC CCTCAACCTG ACTAACCTCC TGCTGCTGGC


 


51
GGTGTTGTTT GCCGTCAGCC TGTCGGTGGG CGTTGCCGAT TTCCGCTGGT


 


101
CGGATGTGTT TTCGCTGTCG GACAGCCAGC AGGTTATGTT CATCAGCCGC


 


151
CTGCCGCGCA CGTTTGCGAT TGTGTTGACG GGCGCGTCGA TGGCGGTGGC


 


201
GGGGATGATT ATGCAGATTC TGATGCGTAA CCGTTTTGTC GAGCCTTCTA


 


251
TGGCGGGCGC GGGTCAGAGT GCGGCTTTGG GTTTGCTTCT GATGTCCCTG


 


301
CTGCTGCCTG CCGCGCCGCT GCCGGTCAAA ATGTCGGTTG CCGCCGTTGC


 


351
CGCGTTAATC GGGATGTTGG TGTTTATGAT GCTTATCCGC CGCCTGCCGC


 


401
CGACGGCGCA ACTGATGGTG CCTTTGGTCG GGATTATTTT CGGCGGCGTG


 


451
GTTGAGGCGG TGGCCACCTT TATTGCGTAT GAAAACGAAA TGCTGCAAAT


 


501
GCTGGGCGTG TGGCAACAGG GCGATTTTTC CGGCGTGTTG CTCGGACGGT


 


551
ATGAACTGTT GTGGGCAACG GGGATTTTGG CTTTGTTTGC CTATTTGATT


 


601
GCCGACCAGC TGACGATTTT GGGTTTGGGC GAAACGGTAA GCGTGAACTT


 


651
GGGGCTGAAC CGGACGGCGA TTCTGTGGTC GGGGCTGATT ATTGTGGCTT


 


701
TGATTACGTC GCTGGTTATC GTTACGGTCG GCAATATTCC GTTTATCGGG


 


751
CTGGTCGTGC CGAACATCAT CAGCCGCCTG ATAGGCGACA GGCTGCGCCA


 


801
AAGCCTGCCT GCGGTGGCTT TGCTGGGTGC GTCTTTGGTT TTATTGTGCG


 


851
ACATTATCGG ACGAGTGATT GTGTTTCCGT TTGAAATTCC GGTATCGACC


 


901
GTCTTCGGCG TATTGGGTAC GGCGTTGTTT TTATGGCTTT TGTTAAGGAA


 


951
ACCTGCTCAT GCCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 2026; ORF 629.a>:










a629.pep




1
MTAKPFSLNL TNLLLLAVLF AVSLSVGVAD FRWSDVFSLS DSQQVMFISR


 


51
LPRTFAIVLT GASMAVAGMI MQILMRNRFV EPSMAGAGQS AALGLLLMSL


 


101
LLPAAPLPVK MSVAAVAALI GMLVFMMLIR RLPPTAQLMV PLVGIIFGGV


 


151
VEAVATFIAY ENEMLQMLGV WQQGDFSGVL LGRYELLWAT GILALFAYLI


 


201
ADQLTILGLG ETVSVNLGLN RTAILWSGLI IVALITSLVI VTVGNIPFIG


 


251
LVVPNIISRL IGDRLRQSLP AVALLGASLV LLCDIIGRVI VFPFEIPVST


 


301
VFGVLGTALF LWLLLRKPAH AV*






m629/a629 95.7% identity in 322 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2027>:









g630.seq (partial)










1
aTgatGATTT TGGTGTGGCT ggctttgttt ccccccatgt tttacggcat



 


51
gtacaacgtc GGCGCACAGG CATTCGGTGC CTTAACGCCC GAtttgctgc


 


101
aacaaagcat cgcccacgac ggcaattacg ccctcgccaa cgctttgggc


 


151
atcaatatgt cccccgaaGc gggcgtgtTg ggcaaaatgc tgttcgGCGC


 


201
GATttacttc ctgccgattt acgcgaccgt aTTTATTGTG GGcggcttct


 


251
ggGaagtCTT GTTCGCATCc gtACGCAAAC ACGAAATCAA CGAAGGTTTC


 


301
TTCGTTACTT CGATTCTGTT TGCCTTAATC GTTCCGCCCA CGCTGCCGCT


 


351
GTGGCAGGCG GCTTTGGGTA TTTCTTTCGG CGTTGTGGTT GCGAAAGAAG


 


401
TATTCGGCGG TACAGGTAAA AACTTCATGA ACCCTGCGCT GGCAGGCCGC


 


451
GCCTTCCTGT TCTTCGCCTA CCCCGCCAAC TTGAGCGGCG ATGCGGTTTG


 


501
GACGGCGGTT GACGGCTATT CCGGCGCAAC CGCGCTGGCG CAATGGGCGG


 


551
CACACGGTGC AGACGGCCTG AAAAACGCCG TAACCGGTCA AACCATCACT


 


601
TGGATGGACG CGTTTATCGG CAAACTGCCC GGCTCCATCG GCGAAGTCTC


 


651
CACTTTGGCA CTCTTAATCG GCGGCGCGTT TATCGTGTTT GCCCGCATCG


 


701
CTtcttgGCG CATTATTGCc ggCGTGATGA TCGGTatGat tGcgatgTCT


 


751
tcgctgatta acttcatCGg ttctgacacc aaagctatgt ttgctatgca


 


801
cttggtacat ggcacttggt GGAaagatGa ttAtcactca ctgtacatta


 


851
aa.....






This corresponds to the amino acid sequence <SEQ ID 2028; ORF 630.ng>:










g630.pep




1
MMILVWLALF PPMFYGMYNV GAQAFGALTP DLLQQSIAHD GNYALANALG


 


51
INMSPEAGVL GKMLFGAIYF LPIYATVFIV GGFWEVLFAS VRKHEINEGF


 


101
FVTSILFALI VPPTLPLWQA ALGISFGVVV AKEVFGGTGK NFMNPALAGR


 


151
AFLFFAYPAN LSGDAVWTAV DGYSGATALA QWAAHGADGL KNAVTGQTIT


 


201
WMDAFIGKLP GSIGEVSTLA LLIGGAFIVF ARIASWRIIA GVMIGMIAMS


 


251
SLINFIGSDT KAMFAMHLVH GTWWKDDYHS LYIK....






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2029>:










m630.seq




1
ATGATGATTT TGGTGTGGCT GGCTTTGTTC CCTGCCATGT TCTACGGTAT


 


51
GTACAACGTC GGCGCGCAGG CATTCGGTGC GTTAACGCCT GATTTGCTGC


 


101
AACAAAACAT CGCCAACGAC TGGCATTACG CCTTTGCCAA CGCTTTGGGC


 


151
ATCAATATGT CGTCTGAAGC GGGCGTGTCG GACAAAATGC TGTTTGGCGC


 


201
GATTTACTTC CTGCCGATTT ACGCGACTGT ATTTGTTGTG GGCGGTTTCT


 


251
GGGAAGTTTT GTTCGCCACC GTGCGCAAAC ACGAAATCAA CGAAGGTTTC


 


301
TTCGTTACTT CGATTCTGTT TGCCTTAATC GTTCCGCCCA CGCTGCCGCT


 


351
GTGGCAGGCG GCTTTGGGTA TTTCTTTCGG CGTTGTGGTT GCGAAAGAAG


 


401
TATTCGGCGG TACAGGTAAA AACTTCATGA ACCCTGCGCT GGCAGGCCGT


 


451
GCTTTCCTGT TCTTCGCCTA CCCTGCCAAC TTGAGCGGCG ATGCGGTTTG


 


501
GACGGCGGTT GACGGCTATT CCGGCGCAAC CGCACTGGCG CAATGGGCGG


 


551
CACACGGTGC AGACGGCCTG AAAAACGCCG TAACCGGTCA AACCATCACT


 


601
TGGATGGACG CGTTTATCGG CAAACTGCCC GGCTCCATTG GCGAAGTCTC


 


651
CACTTTGGCA CTCTTAATCG GCGGCGCGTT TATCGTGTTT GCCCGCATCG


 


701
CTTCTTGGCG CATTATTGCC GGCGTGATGA TCGGTATGAT TGCGATGTCT


 


751
TCGCTGTTCA ACTTCATCGG TTCGGACACC AACGCTATGT TTGCTATGCC


 


801
TTGGTACTGG CACTTGGTGG TCGGCGGCTT CGCCATCGGT ATGCTGTTTA


 


851
TGGCGACCGA CCCTGTTTCC GCTTCCTTTA CCAATGTCGG CAAATGGTGG


 


901
TACGGCGCAC TGATCGGTGT GATGTGCGTA TTAATCCGCG TGGTCAATCC


 


951
GGCTTACCCC GAAGGCATGA TGTTGGCGAT TCTGTTTGCC AACCTGTTTG


 


1001
CCCCGATTTT CGACTATTTC GTCGCACAAG CGAACATCAA ACGCAGAAAG


 


1051
GCGCGCAGCA ATGGCTAA






This corresponds to the amino acid sequence <SEQ ID 2030; ORF 630>:










m630.pep




1
MMILVWLALF PAMFYGMYNV GAQAFGALTP DLLQQNIAND WHYAFANALG


 


51
INMSSEAGVS DKMLFGAIYF LPIYATVFVV GGFWEVLFAT VRKHEINEGF


 


101
FVTSILFALI VPPTLPLWQA ALGISFGVVV AKEVFGGTGK NFMNPALAGR


 


151
AFLFFAYPAN LSGDAVWTAV DGYSGATALA QWAAHGADGL KNAVTGQTIT


 


201
WMDAFIGKLP GSIGEVSTLA LLIGGAFIVF ARIASWRIIA GVMIGMIAMS


 


251
SLFNFIGSDT NAMFAMPWYW HLVVGGFAIG MLFMATDPVS ASFTNVGKWW


 


301
YGALIGVMCV LIRVVNPAYP EGMMLAILFA NLFAPIFDYF VAQANIKRRK


 


351
ARSNG*






m630/g630 93.5% identity in 275 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2031>:










a630.seq




1
ATGATGATTT TGGTGTGGCT GGCTTTGTTC CCTGCCATGT TCTACGGTAT


 


51
GTACAACGTC GGCGCACAGG CATTCGGTGC GTTAACGCCC GATTTGCTGC


 


101
AACAAAGCAT CGCCAACGAC TGGCATTACG CCCTTGCCAA CGCTTTGGGC


 


151
ATCAATATGT CGTCTGAAGC GGGCGTGTTG GGCAAAATGC TGTTCGGCGC


 


201
GATTTACTTC CTGCCGATTT ACGCGACCGT ATTTATTGTC GGCGGTTTCT


 


251
GGGAAGTTTT GTTCGCCACC GTGCGCAAAC ATGAAATCAA CGAAGGTTTC


 


301
TTTGTTACCT CGATTCTGTT TGCCTTAATC GTTCCGCCCA CGCTGCCGCT


 


351
GTGGCAGGCA GCTTTGGGTA TTTCTTTCGG CGTTGTGGTT GCGAAAGAAG


 


401
TATTCGGCGG TACAGGTAAA AACTTCATGA ACCCTGCGCT GGCAGGCCGT


 


451
GCCTTCCTGT TCTTCGCCTA CCCTGCCAAC TTGAGCGGCG ATGCGGTTTG


 


501
GACGGCGGTT GACGGCTATT CCGGCGCAAC CGCGCTGGCG CAATGGGCGG


 


551
CACACGGTGC AGACGGCCTG AAAAACGCCA TAACCGGTCA AACCATCACT


 


601
TGGATGGATG CGTTTATCGG CAAACTGCCC GGCTCCATCG GCGAAGTCTC


 


651
CACTTTGGCA CTCTTAATCG GCGGCGCGTT TATCGTGTTT GCCCGCATCG


 


701
CTTCTTGGCG CATTATTGCC GGCGTGATGA TCGGTATGAT TGCCATGTCT


 


751
TCGCTGTTCA ACTTCATCGG TTCGGACACC AACGCTATGT TTGCTATGCC


 


801
TTGGTACTGG CATTTGGTCG TCGGCGGCTT CGCCATCGGT ATGCTGTTTA


 


851
TGGCGACCGA CCCCGTTTCC GCTTCCTTTA CCAATGTCGG CAAATGGTGG


 


901
TACGGCGCAC TGATCGGTGT GATGTGCGTA TTAATCCGCG TGGTCAATCC


 


951
GGCTTACCCC GAAGGCATGA TGTTGGCGAT TCTGTTTGCC AACCTGTTTG


 


1001
CCCCGATTTT CGACTATTTC GTCGCACAAG CGAACATCAA ACGCAGAAAG


 


1051
GCGCGCAGCA ATGGCTAA






This corresponds to the amino acid sequence <SEQ ID 2032; ORF 630.a>:










a630.pep




1
MMILVWLALF PAMFYGMYNV GAQAFGALTP DLLQQSIAND WHYALANALG


 


51
INMSSEAGVL GKMLFGAIYF LPIYATVFIV GGFWEVLFAT VRKHEINEGF


 


101
FVTSILFALI VPPTLPLWQA ALGISFGVVV AKEVFGGTGK NFMNPALAGR


 


151
AFLFFAYPAN LSGDAVWTAV DGYSGATALA QWAAHGADGL KNAITGQTIT


 


201
WMDAFIGKLP GSIGEVSTLA LLIGGAFIVF ARIASWRIIA GVMIGMIAMS


 


251
SLFNFIGSDT NAMFAMPWYW HLVVGGFAIG MLFMATDPVS ASFTNVGKWW


 


301
YGALIGVMCV LIRVVNPAYP EGMMLAILFA NLFAPIFDYF VAQANIKRRK


 


351
ARSNG*






m630/a630 98.3% identity in 355 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2033>:










g635.seq




1
ATGACCCGGC GACGGGTCGG CAAGCAAAAC CGTATTGCCA TCCACTCCGC


 


51
GCAATACCGA AAAATGGTCG TCTTTGCGGT ATTTCAGATA CACGATGACG


 


101
GGGATTTTCA ACTGCGCGAG CTGTTCGAAA GACAGGGCAT AGCCTTTCGC


 


151
CTCAAAACCC AAATCGGGCA TAATGCGCCG CATATCCTCA AACGACGCGC


 


201
GCATCTGTTC CTTACCCAGT TTTTCCAACA CTTCTTCTTC CGTCAGCTTT


 


251
TGCCCGTAAA AATTGTTCAA AAGCGTCGCC ACCGAAGCCG CCCCGCAGGA


 


301
AAAATCCAAA TCCTGCTTTA CAATATTGAA ATCCCGCCGC GCTTTCCAAC


 


351
TCTGCAATTT GATTTTTCCG TAAACAACAG GATTATCGTT AAACATCGGT


 


401
GCAGCATTCA AACGATAAGA CAAGGGTCTG TACCAGATTA G






This corresponds to the amino acid sequence <SEQ ID 2034; ORF 635.ng>:










g635.pep




1
MTRRRVGKQN RIAIHSAQYR KMVVFAVFQI HDDGDFQLRE LFERQGIAFR


 


51
LKTQIGHNAP HILKRRAHLF LTQFFQHFFF RQLLPVKIVQ KRRHRSRPAG


 


101
KIQILLYNIE IPPRFPTLQF DFSVNNRIIV KHRCSIQTIR QGSVPD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2035>:










m635.seq




1
ATGACCCAGC GACGGGTCGG CAAGCAAAAC CGTATTGCCG TCTATACCGC


 


51
GCAATACCGA GAAATGATCA TCCTTGCGGT ATTTCAGATA CACGATGACG


 


101
GGGATTTGCA ACTGTGCAAG CTGCTCGAAA GACAGGGCAT AGCCTTTCGC


 


151
TTCAAAACCC AAATCAGGCA TAATGCGCCG CATATCCTCA AACGACGCGG


 


201
GCATCTGCTC CTTATCCAGT TTTTTTAACA CGTCCTCTTC CGTCAGCTTT


 


251
TGCCCGTAAA AATTGTTCAA AAGCGTCACC ACCGAAGCCG CCCCGCAGGA


 


301
AAAATCCAAA TCCTGCTTTA CAATATTGAA ATCGCGCCTT TCTTTCCAAC


 


351
TCTGCACTTT GATTTTTCCA TAAGCAACAG GATTATAGTG GATTAA






This corresponds to the amino acid sequence <SEQ ID 2036; ORF 635>:










m635.pep




1
MTQRRVGKQN RIAVYTAQYR EMIILAVFQI HDDGDLQLCK LLERQGIAFR


 


51
FKTQIRHNAP HILKRRGHLL LIQFF*HVLF RQLLPVKIVQ KRHHRSRPAG


 


101
KIQILLYNIE IAPFFPTLHF DFSISNRIIV D*






m635/g635 80.0% identity in 130 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2037>:










a635.seq




1
ATGACCCAGC GACGGGTCGG CAAGCAAAAC CGTATTGCCG TCTATACCGC


 


51
GCAATACCGA GAAATGATCA TCCTTGCGGT ATTTCAGATA CACGATGACG


 


101
GGGATTTGCA ACTGTGCAAG CTGCTCGAAA GACAGGGCAT AGCCTTTCGC


 


151
CTCAAAACCC AAATCAGGCA TGATGCGCCG CATATCCTCA AACGACGCGC


 


201
GCATCTGCTC CTTATCCAGC TTTTTCAACA CGTCCTCTTC CGTCAGCTTT


 


251
TGCCCGTGAA AATTGTTCAA AAGCGTCGCC ACCGAAGCCG CCCCGCAGGA


 


301
AAAATCCAAA TCCTGCTTTA CAATATTGAA ATCGCGCCTT TCTTTCCAAC


 


351
TCTGCACTTT GATTTTTCCA TAAGCAACAG GATTATAGTG GATTAA






This corresponds to the amino acid sequence <SEQ ID 2038; ORF 635.a>:










a635.pep




1
MTQRRVGKQN RIAVYTAQYR EMIILAVFQI HDDGDLQLCK LLERQGIAFR


 


51
LKTQIRHDAP HILKRRAHLL LIQLFQHVLF RQLLPVKIVQ KRRHRSRPAG


 


101
KIQILLYNIE IAPFFPTLHF DFSISNRIIV D*






m635/a635 95.4% identity in 131 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2039>:










g638.seq




1
ATGATTGGCG GACAGTTTAT CGTAGttgGc atTGTAGGCA AAAACGCACT


 


51
TGCCCGCTTT GTTGATAATA ttgtcGTGAA TAtcGGAATA GTTGACATAG


 


101
TTGAGCATGA TGCCCTAATC GCGGCTGCCG ACGGCGATAT TGTCGAACAC


 


151
TTTGAGCCGT TCGGAAAACA TCAGCACATA GCCCATATTG TtgcCCACGG


 


201
AAATATTGCC GCTGacttcg ctgtcgTTGG TGTACATATA GTGGACGGCG


 


251
AAACGCAGGT CGCTGAAGCG GTTGTTTTTA TAGGTGTTGT GCGTGCTGGT


 


301
ATTGGAAAAA ATGCCGTCCC GCCCTTTGGA AATGTCGTTG ccgACGACCT


 


351
GCGCgccggg CgcgtTCCAA ACGGTAACGC CATTGCCGCG CTCATTCACG


 


401
CGCAAGGTcg catcgCCGAC GATTTTATTC TCGCGCACCA TCGCATCGGC


 


451
AGAACCATGA AGGTATACGC CGAACGAATT ATCAAAAATA TTGTTGTGTT


 


501
CAACCAGGGC GCGCGGGGCG GCTTTTTCGA GATAAATACC GGCATCCATT


 


551
GCTGGCAGGC TCATACCGGA ACGGGTAACG GTCAGGTTGC GGAGCGTTAC


 


601
GTCCGGCGCG TGTACGGCTA TGGTACGCCC GCTCTTGTCC CCTTCGATGG


 


651
TTGCGGAACG GTCGGCAGGC CCTTCAATCG TAATCGGTTT GTCGATATAA


 


701
AGTTTGGTTT GATATACGCC GGAAGCCAGT TTGATCGTAT CGCCCGCCCG


 


751
GGCGCGGGCA AAAATTTCGG CAAGGTTGTC TTGCGGGGAA ACGTGGACGA


 


801
CGGCTGCCGA TGCCGTCTGA AAAATGCTGC CGGCGGCAAG TATCAGCACG


 


851
GCCTTCAGCC ATATACGGAG CGCGGATGTG TGCATAGTGT CCCTCTGTTT


 


901
CGTTCGGTAT GGCCGAACAA AATAAAGCAT CATTCAAATG TGCCTGTTTT


 


951
TATAGCGAAA CCGCCTGAAA CGGTACGGCA AGCGGTTTGG CTATAA






This corresponds to the amino acid sequence <SEQ ID 2040; ORF 638.ng>:










g638.pep




1
MIGGQFIVVG IVGKNALARF VDNIVVNIGI VDIVEHDALI AAADGDIVEH


 


51
FEPFGKHQHI AHIVAHGNIA ADFAVVGVHI VDGETQVAEA VVFIGVVRAG


 


101
IGKNAVPPFG NVVADDLRAG RVPNGNAIAA LIHAQGRIAD DFILAHHRIG


 


151
RTMKVYAERI IKNIVVFNQG ARGGFFEINT GIHCWQAHTG TGNGQVAERY


 


201
VRRVYGYGTP ALVPFDGCGT VGRPFNRNRF VDIKFGLIYA GSQFDRIARP


 


251
GAGKNFGKVV LRGNVDDGCR CRLKNAAGGK YQHGLQPYTE RGCVHSVPLF


 


301
RSVWPNKIKH HSNVPVFIAK PPETVRQAVW L*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2041>:










m638.seq




1
ATGATTGGCG AAAAGTTTAT CGTAGTTGGC ATTATAGGCA AATACGCACT


 


51
TGCCTGCCTT GTTGATAATG TTGTCGTGAA TATCGGAATA GTTGACATAG


 


101
TTGAGCATAA TGCCCTGATC GCGGCTGCCG ACGGCGATAT TGTCGAATAC


 


151
TTTGAGCCGC TCGGAAAACA TCAGCACATA GCCCATATTG TTGCCCACGG


 


201
AAATATTGCC GCTGATTTCG CTGTCGTTGG TGTACATATA GTGGACGGCG


 


251
AAACGCAAAT CGCTGAAGCG GTTGTTTTTG TAGGTGTTGT GCGTGCTGGT


 


301
ATTGGAAAAA ATGCCGTCCC GCCCTTTGGA AATGTCGTTG CCGACGACCT


 


351
GCGCACCGGG TGCGTTCCAA ACGGTAACGC CGTTGCCGCG CTCGTTCACG


 


401
CGCAAAGTCG CGTCGCCGAC GATTTTATTC TCGCGCACCA TCGCATCGGC


 


451
AGAACCATGC AGATATACGC CGACCGAATT ATCCAAAATA TTGTTGTGTT


 


501
CAATCAGGGC GCGCGGGGCA GTTTCTTCGA GATAAATACC GGCATCCATT


 


551
GCGGGCAGGC TCATACCGGA ACGGGTAACG GTCAGGTTGC GGAGCGTTAC


 


601
GTCCGGCGCG TGTACGGCTA TGGTACGCCC GCTCCTGTCG CCTTCGATGG


 


651
TTGCGGAACG GTCGGCAGGC CCTTCAATCG TAATCGGTTT GTCAATGTGA


 


701
AGTTTGGTTT TATATACGCC GGAAGCCAGT TTGAGCGTAT CGCCCGCCCG


 


751
GGCGCGGGCA AATGCGGGAT ACCGATCAGC ATAATCGGTT CGTGA






This corresponds to the amino acid sequence <SEQ ID 2042; ORF 638>:










m638.pep




1
MIGEKFIVVG IIGKYALACL VDNVVVNIGI VDIVEHNALI AAADGDIVEY


 


51
FEPLGKHQHI AHIVAHGNIA ADFAVVGVHI VDGETQIAEA VVFVGVVRAG


 


101
IGKNAVPPFG NVVADDLRTG CVPNGNAVAA LVHAQSRVAD DFILAHHRIG


 


151
RTMQIYADRI IQNIVVFNQG ARGSFFEINT GIHCGQAHTG TGNGQVAERY


 


201
VRRVYGYGTP APVAFDGCGT VGRPFNRNRF VNVKFGFIYA GSQFERIARP


 


251
GAGKCGIPIS IIGS*






m638/g638 88.2% identity in 254 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2043>:










a638.seq




1
ATGATTGGCG GACAGTTTAT CGTAGTTGGC ATTGTAGGCA AAAACGCACT


 


51
TGCCCGCTTT GTTGATAATG TTGTCGTGAA TATCGGAATA GTTGACATAG


 


101
TTGAGCATGA TGCCTTGGTC GCGGCTGCCG ACGGCGATAT TGTCAAACAC


 


151
TTTGAGCCGC TCGGAAAACA TCAGCACATA GCCCATATTG TTGCCCACGG


 


201
AAATATTGCC GCTGATTTCG CTGTCGTTGG TGTACATATA GTGGACGGCG


 


251
AAACGCAAAT CGCTGAAGCG GTTGTTTTTA TAGGTGTTGT GCGTGCTGGT


 


301
ATTGGAAAAA ATGCCGTCCC GCCCTTTGGA AATATCGTTG CCGACGACCT


 


351
GCGCGCCGGG CGCGTTCCAA ACGGTAACGC CATTGCCGCG CTCGTTCACG


 


401
CGCAAAGTCG CGTCGCCGAC GATTTTATTC TCCCGCACCA TCGCATCGGC


 


451
AGAACCATGC AGATAGACGC CGACCGAATT ATCCAAAATA TTATTGTGTT


 


501
CAATCAGGGC GCGCGGGGCA GTTTCTTCGA GATAAATACC GGCATCCATT


 


551
GCGGGCAGGC TCATACCGGA ACGGGTAACG GTCAGGTTGC GGAGCGTTAC


 


601
GTCCGGCGCG TGTACGGCTA TGGTACGCCC GCTCCTGTCT CCTTCGATGG


 


651
TTGCAGAACG GTCGGCAGGC CCTTCAATCG TAATCGGTTT GTCGATGTGA


 


701
AGTTTGGTTT GATATACGCC GGAAGCCAGT TTGAGCGTAT CGCCCGCCCG


 


751
GGCGCGGGCA AATGCGGGAT ACCGATCAGC ATAATCGACT CATGGTGA






This corresponds to the amino acid sequence <SEQ ID 2044; ORF 638.a>:










a638.pep




1
MIGGQFIVVG IVGKNALARF VDNVVVNIGI VDIVEHDALV AAADGDIVKH


 


51
FEPLGKHQHI AHIVAHGNIA ADFAVVGVHI VDGETQIAEA VVFIGVVRAG


 


101
IGKNAVPPFG NIVADDLRAG RVPNGNAIAA LVHAQSRVAD DFILPHHRIG


 


151
RTMQIDADRI IQNIIVFNQG ARGSFFEINT GIHCGQAHTG TGNGQVAERY


 


201
VRRVYGYGTP APVSFDGCRT VGRPFNRNRF VDVKFGLIYA GSQFERIARP


 


251
GAGKCGIPIS IIDSW*






m638/a638 91.3% identity in 264 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2045>:










g639-1.seq




1
ATGAGCCTGC CAGCAATGGA TGCCGGTATT TATCTCGAAA AAGCCGCCCC


 


51
GCGCGCCCTG GTTGAACACA ACAATATTTT TGATAATTCG TTCGGCGTAT


 


101
ACCTTCATGG TTCTGCCGAT GCGATGGTGC GCGAGAATAA AATCGTCGGC


 


151
GATGCGACCT TGCGCGTGAA TGAGCGCGGC AATGGCGTTA CCGTTTGGAA


 


201
CGCGCCCGGC GCGCAGGTCG TCGGCAACGA CATTTCCAAA GGGCGGGACG


 


251
GCATTTTTTC CAATACCAGC ACGCACAACA CCTATAAAAA CAACCGCTTC


 


301
AGCGACCTGC GTTTCGCCGT CCACTATATG TACACCAACG ACAGCGAAGT


 


351
CAGCGGCAAT ATTTCCGTGG GCAACAATAT GGGCTATGTG CTGATGTTTT


 


401
CCGAACGGCT CAAAGTGTTC GACAATATCG CCGTCGGCAG CCGCGATTAG


 


451
GGCATCATGC TCAACTATGT CAACTATTCC GATATTCACG ACAATATTAT


 


501
CAACAAAGCG GGCAAGTGCG TTTTTGCCTA CAATGCCAAC TACGATAAAC


 


551
TGTCCGCCAA TCATTTTGAA AACTGCCAAA TCGGCATGCA CTTTACCGCC


 


601
GCCATCGAAG GCACGTCCCT GCACGACAAT TCCTTTATCA ACAACGGAAG


 


651
CCAGGTCAAA TATGTCAGTA CGCGCTTTCT CGACTGGAGC GAGGGCGGAC


 


701
ACGGCAACTA CTGGAGCGAC AACAGCCCGT TCGATTTGAA CGGCGACGGC


 


751
TTCGGAGACA GCGCGTACCG TCCCGACGGC ATCATCGACC AAATCATCTG


 


801
GCGCGCGCCC GTATCGCGCC TCTTGATGAA CAGTCCCGCA ATCAGCATCG


 


851
TCAAATGGGC GCAGGCGCAG TTTCCCGCCG TTCTGCCCGG CGGCGTGGTG


 


901
GACAGCAAAC CGCTGATGAA GCCTTATGCC CCCAAAATTC AAACCCGTTA


 


951
TCAGGCGATG AAGGACGAGT TGCTCAAAGA AGCCGAAACG CGGCAGTCGG


 


1001
AACGGGGCAG GGCGGAAAAC GGTTCTTTGA ACTAG






This corresponds to the amino acid sequence <SEQ ID 2046; ORF 639-1.ng>:










g639-1.pep




1
MSLPAMDAGI YLEKAAPRAL VEHNNIFDNS FGVYLHGSAD AMVRENKIVG


 


51
DATLRVNERG NGVTVWNAPG AQVVGNDISK GRDGIFSNTS THNTYKNNRF


 


101
SDLRFAVHYM YTNDSEVSGN ISVGNNMGYV LMFSERLKVF DNIAVGSRD*


 


151
GIMLNYVNYS DIHDNIINKA GKCVFAYNAN YDKLSANHFE NCQIGMHFTA


 


201
AIEGTSLHDN SFINNGSQVK YVSTRFLDWS EGGHGNYWSD NSPFDLNGDG


 


251
FGDSAYRPDG IIDQIIWRAP VSRLLMNSPA ISIVKWAQAQ FPAVLPGGVV


 


301
DSKPLMKPYA PKIQTRYQAM KDELLKEAET RQSERGRAEN GSLN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2047>:










m639-1.seq




1
ATGAGCCTGC CCGCAATGGA TGCCGGTATT TATCTCGAAG AAACTGCCCC


 


51
GCGCGCCCTG ATTGAACACA ACAATATTTT GGATAATTCG GTCGGCGTAT


 


101
ATCTGCATGG TTCTGCCGAT GCGATGGTGC GCGAGAATAA AATCGTCGGC


 


151
GACGCGACTT TGCGCGTGAA CGAGCGCGGC AACGGCGTTA CCGTTTGGAA


 


201
CGCACCCGGT GCGCAGGTCG TCGGCAACGA CATTTCCAAA GGGCGGGACG


 


251
GCATTTTTTC CAATACCAGC ACGCACAACA CCTACAAAAA CAACCGCTTC


 


301
AGCGATTTGC GTTTCGCCGT CCACTATATG TACACCAACG ACAGCGAAAT


 


351
CAGCGGCAAT ATTTCCGTGG GCAACAATAT GGGCTATGTG CTGATGTTTT


 


401
CCGAGCGGCT CAAAGTATTC GACAATATCG CCGTCGGCAG CCGCGATCAG


 


451
GGCATTATGC TCAACTATGT CAACTATTCC GATATTCACG ACAACATTAT


 


501
CAACAAGGCA GGCAAGTGCG TATTTGCCTA TAATGCCAAC TACGATAAAC


 


551
TTTTCGCCAA TCATTTTGAA AACTGTCAAA TCGGCATACA CTTTACCGCC


 


601
GCCATCGAAG GCACGTCCTT GCATGACAAT TCCTTTATCA ACAACGAAAG


 


651
CCAGGTCAAA TACGTCAGCA CGCGCTTTCT CGATTGGAGC GAGGGCGGAC


 


701
ACGGCAACTA TTGGAGCGAC AACAGCGCGT TCGATTTGAA CGGCGACGGC


 


751
TTCGGAGACA GCGCGTACCG CCCCAACGGC ATCATCGACC AAATCATCTG


 


801
GCGCGCGCCC GTATCGCGCC TTTTGATGAA CAGTCCCGCA ATCAGCATCG


 


851
TCAAATGGGC GCAGGCGCAG TTTCCCGCCG TTCTGCCTGG CGGCGTGGTG


 


901
GACAGCAAAC CGCTGATGAA GCCTTATGCC CCCAAAATTC AAACCCGTTA


 


951
TCAGGCGATG AAGGACGAGC TACTCAAAGA AGTCGAAACG CGGCAGTCGG


 


1001
AATGGGGCAG GGCGGAAAAC GGTTCTTTGA ACTAG






This corresponds to the amino acid sequence <SEQ ID 2048; ORF 639-1>:










m639-1.pep




1
MSLPAMDAGI YLEETAPRAL IEHNNILDNS VGVYLHGSAD AMVRENKIVG


 


51
DATLRVNERG NGVTVWNAPG AQVVGNDISK GRDGIFSNTS THNTYKNNRF


 


101
SDLRFAVHYM YTNDSEISGN ISVGNNMGYV LMFSERLKVF DNIAVGSRDQ


 


151
GIMLNYVNYS DIHDNIINKA GKCVFAYNAN YDKLFANHFE NCQIGIHFTA


 


201
AIEGTSLHDN SFINNESQVK YVSTRFLDWS EGGHGNYWSD NSAFDLNGDG


 


251
FGDSAYRPNG IIDQIIWRAP VSRLLMNSPA ISIVKWAQAQ FPAVLPGGVV


 


301
DSKPLMKPYA PKIQTRYQAM KDELLKEVET RQSEWGRAEN GSLN*






g639-1/m639-1 95.9% identity in 344 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2049>:










a639-1.seq




1
ATGAGCCTGC CCGCAATGGA TGCCGGTATT TATCTCGAAG AAACTGCCCC


 


51
GCGCGCCCTG ATTGAACACA ATAATATTTT GGATAATTCG GTCGGCGTCT


 


101
ATCTGCATGG TTCTGCCGAT GCGATGGTGC GGGAGAATAA AATCGTCGGC


 


151
GACGCGACTT TGCGCGTGAA CGAGCGCGGC AATGGCGTTA CCGTTTGGAA


 


201
CGCGCCCGGC GCGCAGGTCG TCGGCAACGA TATTTCCAAA GGGCGGGACG


 


251
GCATTTTTTC CAATACCAGC ACGCACAACA CCTATAAAAA CAACCGCTTC


 


301
AGCGATTTGC GTTTCGCCGT CCACTATATG TACACCAACG ACAGCGAAAT


 


351
CAGCGGCAAT ATTTCCGTGG GCAACAATAT GGGCTATGTG CTGATGTTTT


 


401
CCGAGCGGCT CAAAGTGTTT GACAATATCG CCGTCGGCAG CCGCGACCAA


 


451
GGCATCATGC TCAACTATGT CAACTATTCC GATATTCACG ACAACATTAT


 


501
CAACAAAGCG GGCAAGTGCG TTTTTGCCTA CAATGCCAAC TACGATAAAC


 


551
TGTCCGCCAA TCATTTTGAA AACTGCCAAA TCGGCATACA CTTTACCGCC


 


601
GCCATCGAAG GCACGTCCCT GCACGACAAT TCCTTTATCA ACAACGAAAG


 


651
CCAGGTCAAA TACGTCAGCA CGCGCTTTCT CGACTGGAGC GAGGGCGGAC


 


701
ACGGCAACTA TTGGAGCGAC AACAGCGCGT TCGATTTGAA CGGCGACGGC


 


751
TTCGGAGACA GCGCGTACCG TCCCAACGGC ATCATCGACC AAATCATCTG


 


801
GCGCGCACCC GTATCGCGCC TCTTGATGAA CAGTCCCGCA ATCAGCATCG


 


851
TCAAATGGGC GCAGGCGCAA TTTCCCGCCG TTTTGCCTGG CGGCGTGGTG


 


901
GACAGCAAAC CGCTGATGAA GCCTTATGCC CCCAAAATTC AAACCCGTTA


 


951
TCAGGCGATG AAGGACGGGC TGCTCAAAAA AGTCGAAACG CGGCAGTTGG


 


1001
AATGGGGCAG GGCGGAAAAC GGTTCTTTGA ACTAG






This corresponds to the amino acid sequence <SEQ ID 2050; ORF 639-1.a>:










a639-1.pep




1
MSLPAMDAGI YLEETAPRAL IEHNNILDNS VGVYLHGSAD AMVRENKIVG


 


51
DATLRVNERG NGVTVWNAPG AQVVGNDISK GRDGIFSNTS THNTYKNNRF


 


101
SDLRFAVHYM YTNDSEISGN ISVGNNMGYV LMFSERLKVF DNIAVGSRDQ


 


151
GIMLNYVNYS DIHDNIINKA GKCVFAYNAN YDKLSANHFE NCQIGIHFTA


 


201
AIEGTSLHDN SFINNESQVK YVSTRFLDWS EGGHGNYWSD NSAFDLNGDG


 


251
FGDSAYRPNG IIDQIIWRAP VSRLLMNSPA ISIVKWAQAQ FPAVLPGGVV


 


301
DSKPLMKPYA PKIQTRYQAM KDGLLKKVET RQLEWGRAEN GSLN*






a639-1/m639-1 98.8% identity in 344 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2051>:










g640.seq




1
ATGATTCATA TAATATCAAT ATTAAAGAGT ATCGGTATAT CGGGGATAGC


 


51
TATGTCCTGT TTTTCAATCC GGCGTATGTC TGCGTTTCGG GCGCGGATAA


 


101
CGGCGTTTTT TACCGCCTTT GTCTTTTTGA CGGcggcACT GCCCGCTTAT


 


151
GcggAgcgTc tgcctGATTT TCTGgcgAAA ATacAgcctT CGGAAATTTT


 


201
TCCGGGTGCG GATCGTTACG GCAAGCCGGA aggcAAGCCT AtggtTGCCC


 


251
GCgtttACAA AGgcgATGAG CAGCTCGGTT TGGTTTATAT CACGACCGAT


 


301
GCGGTCAATA CGCGCGGTTA TTCGAGCAAA CCGATCGATA CGCTGATGGC


 


351
TTTGGCAAAC GACGGCACGA TAGCCGGGGC GAAACTGGTC GATCATCACG


 


401
AACCGATTAT GCTGATCGGT ATCCCGCAAT CGCGTGTCGA TAAGTTCATC


 


451
GACAAATATA TCGGTCTGAA TTTTATTAAA AATCCGCCGA CCCCGAGCGT


 


501
GGCGCCGGGC GACATCATCA GcggtGCGAC TgttaCACTG ATGGTGGTTA


 


551
ACGACAGCAT CCAGCGTTCG TACAAGGTCA TTGCCAACCA ATACCGTCTG


 


601
GGTTCGGACA AGGCCCTTCA GACGGCATCC GCTTCCGATG TTCGGGAAGC


 


651
CGCGCCTGCG TCAGAAACCC GTCCGCGCCG TATGGCAAAT CCCGACAAGC


 


701
AGGATATTTT GTCTTGGGAC GAACTTTTGA AACAAAAGGC CGTCGGCCAT


 


751
CTGCATATCA CGCTCGATCA AATCAACAAA CTGTTTGAGA AAGGCGGCAA


 


801
GGCCGGCGTG GCCGATCACG CCGAACAGGG CGATCCTGAC GATACCTTTA


 


851
TTGATTTGTA TGTTGCCTTG GTCAGCCAGC CTTCCATCGG TAAAAGCCTG


 


901
CTGGGTGAGG ACGGCTGGGC GCATCTGCAA AAACGGCTGA AACCCGGGCA


 


951
GCAGGCGGTT TTGGTTGCCG GAGAGGGCCG TTATTCTTGG AAAGGTTCGG


 


1001
GCTATGTGCG CGGCGGTATT TTCGACCGTA TCGAGATGAT TCAGGGGGAG


 


1051
AACAGCTTCC GTTTTACCGA TGCCCAACAC GAACGCGTCG TCGAGCTGTC


 


1101
TGCCGCCGAT GCGCCGCGTT TTAAAGAAGT TTCTTGGTTT ACCATCCCTG


 


1151
AAGGCGTAGC GTTTGACGGT GCGGAGCCGT GGCGGCTGTA A






This corresponds to the amino acid sequence <SEQ ID 2052; ORF 640.ng>:










g640.pep




1
MIHIISILKS IGISGIAMSC FSIRRMSAFR ARITAFFTAF VFLTAALPAY


 


51
AERLPDFLAK IQPSEIFPGA DRYGKPEGKP MVARVYKGDE QLGLVYITTD


 


101
AVNTRGYSSK PIDTLMALAN DGTIAGAKLV DHHEPIMLIG IPQSRVDKFI


 


151
DKYIGLNFIK NPPTPSVAPG DIISGATVTL MVVNDSIQRS YKVIANQYRL


 


201
GSDKALQTAS ASDVREAAPA SETRPRRMAN PDKQDILSWD ELLKQKAVGH


 


251
LHITLDQINK LFEKGGKAGV ADHAEQGDPD DTFIDLYVAL VSQPSIGKSL


 


301
LGEDGWAHLQ KRLKPGQQAV LVAGEGRYSW KGSGYVRGGI FDRIEMIQGE


 


351
NSFRFTDAQH ERVVELSAAD APRFKEVSWF TIPEGVAFDG AEPWRL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2053>:









m640.seq (partial)










1
ATGATTCATA TAATATCAAT ATTAAAGAGT ATCGGTATAT CGGGGATAGT



 


51
CATGTCCTGT TTTTCAATCA AACGTATGTC CGCGTTTCGG GCGCGGATAA


 


101
CGGCGTTTTT TGCCGCCTTT GTCTTTTTGA CGGCGGCACT GCCCGCTTAT


 


151
GCGGAGCGTC TGCCTGATTT TCTGGCGAAA ATACAGCCTT CGGAAATTTT


 


201
TCCGGGTGCG GACCGTTACG GCAAGCCGGA AGGTAAGCCT ATGGTTGCCC


 


251
GCGTTTACAA AGGCGATGAG CAGTTGGGCT TGGTCTATAT CACGACCGAT


 


301
GCGGTCAATA CGCGCGGTTA TTCGAGCAAA CCGATTGATA CGCTGATGGT


 


351
GTTGGCAAAC GACGGCACGA TAGCCGGGGC GAAACTGGTC GACCATCACG


 


401
AACCGATTAT GCTGATCGGT ATCCCGCAT...






This corresponds to the amino acid sequence <SEQ ID 2054; ORF 640>:









m640.pep (partial)










1
MIHIISILKS IGISGIVMSC FSIKRMSAFR ARITAFFAAF VFLTAALPAY



 


51
AERLPDFLAK IQPSEIFPGA DRYGKPEGKP MVARVYKGDE QLGLVYITTD


 


101
AVNTRGYSSK PIDTLMVLAN DGTIAGAKLV DHHEPIMLIG IPH...






m640/g640 96.5% identity in 143 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2055>:









a640.seq (partial)










1
ATGATTCATA TAATATCAAT ATTAAAGAGT ATCGGTATAT CGGGGATAGT



 


51
CATGTCCTGT TTTTCAATCA AACGTATGTC CGCGTTTCGG GCGCGGATAA


 


101
CGGCGTTTTT TGCCGCCTTT GTCTTTTTGA CGGCGGCACT GCCCGCTTAT


 


151
GCGGAGCGTC TGCCTGATTT TCTGGCGAAA ATACAGCCTT CGGAAATTGT


 


201
TCCGGGTGCG GACCGTTACA GCAAGCCGGA AGGTAAGCCT ATGGTTGCCC


 


251
GCGTTTACAA AGGCGATGAG CAGTTGGGCT TGGTCTATAT CACGACCGAT


 


301
GCGGTCAATA CGCGCGGTTA TTCGAGCAAA CCGATTGATA CGCTGATGGC


 


351
GTTGGCTAAA GACGGTACGA TAGCCGGAGC GAAATTGGTT GATCACCATG


 


401
AGTCGATTAT GCTGATCGGT ATCCCGCAT...






This corresponds to the amino acid sequence <SEQ ID 2056; ORF 640.a>:









a640.pep (partial)  Length: 143










1
MIHIISILKS IGISGIVMSC FSIKRMSAFR ARITAFFAAF VFLTAALPAY



 


51
AERLPDFLAK IQPSEIVPGA DRYSKPEGKP MVARVYKGDE QLGLVYITTD


 


101
AVNTRGYSSK PIDTLMALAK DGTIAGAKLV DHHESIMLIG IPH...






m640/a640 96.5% identity in 143 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2057>:










g642.seq




1
ATGCGGTATC CGCCGCAATC GGCGGTTTTG CAGAATGCCG CGCGTTGCCT


 


51
TTTGCGCCGC CCGAAATCTG CCTGCCGCCG TATTTGCCCG CTATCCGCAA


 


101
TATCGGCAGT CCAATATATC TTTGCGGATG TCGTTCAGCA GGAAGGCTGT


 


151
GGTGTCTTCG TGTTCCTCCT GTACGAAGAC AAAAAGTCGG GCGATGATTT


 


201
TGCCGATGAA GACTTTTTGC AGGGCGCAGG CGTCGGTCAG GGTGTGTTCC


 


251
TGCAGGAAGC TGCGGATGTC TTCGGGCAAA GCGTAgtCgc gGGCAACGGC


 


301
GGcaaagcgG ACatcggtTT Gcacggcgtc gagCAGGGtt tggtTTTTGT


 


351
CCAACTTAAT GCCTGCTTCT TTTTCTTCGG CGGTGGCGCG GACGAACTGG


 


401
TCGTAAATTT CGGCATAAAG CATATCGTTC GGGCCTTCAA AAATCGTGAA


 


451
GGGGCGGATA TCGATGGCGA TATTGCCGGC TGGGTGTCCG CGTTCAAAAC


 


501
CCTTCGCGCC CAAGAGTTTT TGCAACATTT GCGCGGCGgc gTAAGTGTAT


 


551
TCCGTGGCGa ggGTTTTGAc gatgTTCGCC TCCATCAATT GATGGGCGAc


 


601
ggGCGcgacg ggCGAAACGG AATGGCAGAC GTAGCGGTAA AGGATTTCGG


 


651
AAACCTGATG GCGGCGTTGG ATTTCGCGGC GTTCGTAATC GACGAATCTG


 


701
ATATCGTTGC GGACATATCG GTTCAGGTTG TCAAGGATGT ATTCCATAAT


 


751
GCCGTGCGTC ATGCCGATCA GTTGCAGGCG GCTGCGGATA AAGATGTTTT


 


801
GGAACGCGCG CAAACCGGCA GCGTCGCCCC GGGAGAGTTT CATCACGGCG


 


851
GTTGCAGGCA TTTCGGCATC GATGCGGTTG ACGGCGTAAC GGACGGCGCG


 


901
CAGGCCTTCG GATGCGAGGG TTTCGCAGCG GATGTATGTT TTGGGGACGA


 


951
GCAGCAGGTC GATGactttg gcgagtttgC Cgtttttgcg ctctttggcg


 


1001
gcaacgaggA GGAAGTCGCT TTGCGAATTG CCCTGCCAGT ATTTCGCGGC


 


1051
GttgACGTAA ATGGTTtgtt cgtcggtata ttcgtagcag gactgcaTTT


 


1101
CGCGTGCAAt cgCcgcgccg gaggtTtcgg gttcggtaAc gcccaaacgg


 


1151
cggctttcgc ctTTGAAAAT CATGTCCAAA CCTTGTGCGA CTTGCgcttc


 


1201
gccgccgaac tCTTGCAGAG GCTGCAACAC CAGCGCGCCT TCGATGCCGG


 


1251
TACGCAGCGT AACGGGCACG CCGTAATGCC CCGCAATCCT TAG






This corresponds to the amino acid sequence <SEQ ID 2058; ORF 642.ng>:










g642.pep




1
MRYPPQSAVL QNAARCLLRR PKSACRRICP LSAISAVQYI FADVVQQEGC


 


51
GVFVFLLYED KKSGDDFADE DFLQGAGVGQ GVFLQEAADV FGQSVVAGNG


 


101
GKADIGLHGV EQGLVFVQLN ACFFFFGGGA DELVVNFGIK HIVRAFKNRE


 


151
GADIDGDIAG WVSAFKTLRA QEFLQHLRGG VSVFRGEGFD DVRLHQLMGD


 


201
GRDGRNGMAD VAVKDFGNLM AALDFAAFVI DESDIVADIS VQVVKDVFHN


 


251
AVRHADQLQA AADKDVLERA QTGSVAPGEF HHGGCRHFGI DAVDGVTDGA


 


301
QAFGCEGFAA DVCFGDEQQV DDFGEFAVFA LFGGNEEEVA LRIALPVFRG


 


351
VDVNGLFVGI FVAGLHFACN RRAGGFGFGN AQTAAFAFEN HVQTLCDLRF


 


401
AAELLQRLQH QRAFDAGTQR NGHAVMPRNP *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2059>:









m642.seq (partial)










1
GCCTGCCGCC GTATTTGCCC GCTACCCGCA ATATCGGCAG TCCAATATAT



 


51
CTTTGCGGAT GTCGTTCAGC AGGAAGGCTG CGGTGTCTTC GTGTTTCGCC


 


101
TGTACGAAGA CAAAGAGTCG GGCGATGATT TTGCCGATAA AGACTTTTTG


 


151
CAGGGCGCAG GCATCGGTCA GGGTGTGTTC CTGCAGGAAG CTGCGGATGT


 


201
CTTCAGGCAA AGTGTAGTCG CGGGCGACGG CGGCAAAGCG GGCATCGGTT


 


251
TGCAGGCGGT CGAGCAGGGT TTGGTTTTTG TCCAACTTCA TGCCTGCTTC


 


301
TTTTTCTTCG GCGGTGGCGC GGACAAACTG GTCGTAAATT TCGGCATAAA


 


351
GCATATCGTT CGGGCCTTCA AAAATCGTGA AGGGGCGGAT GTCGATAGCG


 


401
ATATTGCCGG CGGTGTGTCC GCGTTCAAAA CCCTTCGCAC CCAAGAGTTT


 


451
TTGCAACATT TGCGCGGCGG CGTAAGTGTA TTCCGTGGCG AGGGTTTTGA


 


501
CGATGTTCGC CTCCATCAGC TGATGGGCGA CGGGGGCAAC AGGCGAAACG


 


551
GAATGGCAGA CGTAGCGGTA AAGAATCTCG GAAACCTGAT GGCGGCGCCG


 


601
GATTTCGCGG CGTTCGTAAT CGACGAATTT GATGTCGTTG CGGACGTATC


 


651
GTTCCAGATT TTCAAGGATG TATTCCATAA TGCCGTGCGT CATGCCGATC


 


701
AGTTGCAGGC GGCTGCGGAT AAAGATGTTT TGGAACGCGC GCAAACCGGC


 


751
AGCGTCGCTC TGGGAGAGTT TCATCACGGC GGTTGCAGGC ATTTCGGCAT


 


801
CGATGCGGTT GACGGCGTAA CGGACGGCGC GCAAGCCTTC GGATGCGAGG


 


851
GTTTCGCAGC GGATGTATGT TTTGGGGACG AGCAGCAGGT CGATGACTTT


 


901
GGCGAGTTTG CCGTTTTTGC GCTCTTTGGC GGCAACGAGG AGGAAGTCGC


 


951
TTTGCGAGTT GCCCTGCCAG TATTTCGCGG CGTTGACGTA AATGGTTTGT


 


1001
CCGTCGATAT ATTCGTAGTA GGACTGCATT TCGCGTGCAA TCGCCGCGCC


 


1051
GGAGGTTTCG GGTTCGGTAA CACCCAAACC GCCGCCCTCG CCTTTGAAAA


 


1101
TCATCTCCAA ACCTTGCGCG ACTTGCGCTT CATCGCCGAA CTCTTGCAGT


 


1151
GGCTGCAACA CCAGCGCGCC TTCGATGCCG GTACGCAGCG TAACGGGCAC


 


1201
GCCGTAATGC CCCGCAATCC G






This corresponds to the amino acid sequence <SEQ ID 2060; ORF 642>:









m642.pep (partial)










1
ACRRICPLPA ISAVQYIFAD VVQQEGCGVF VFRLYEDKES GDDFADKDFL



 


51
QGAGIGQGVF LQEAADVFRQ SVVAGDGGKA GIGLQAVEQG LVFVQLHACF


 


101
FFFGGGADKL VVNFGIKHIV RAFKNREGAD VDSDIAGGVS AFKTLRTQEF


 


151
LQHLRGGVSV FRGEGFDDVR LHQLMGDGGN RRNGMADVAV KNLGNLMAAP


 


201
DFAAFVIDEF DVVADVSFQI FKDVFHNAVR HADQLQAAAD KDVLERAQTG


 


251
SVALGEFHHG GCRHFGIDAV DGVTDGAQAF GCEGFAADVC FGDEQQVDDF


 


301
GEFAVFALFG GNEEEVALRV ALPVFRGVDV NGLSVDIFVV GLHFACNRRA


 


351
GGFGFGNTQT AALAFENHLQ TLRDLRFIAE LLQWLQHQRA FDAGTQRNGH


 


401
AVMPRNP






m642/g642 90.4% identity in 407 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2061>:









a642.seq (partial)










1
GCCTGCCGCC GTATTTGCCC GCTATCCGCA ATATCGGCAG TCCAATATGT



 


51
CTTTGCGGAT GTCGTTCAGC AGGAAGGCTG CGGTGTCTTC GTGTTCCGCC


 


101
TGTACGAAGA CAAAGAGTCG GGCGATGATT TTGCCGATAA AGACTTTTTG


 


151
CAGGGCGCAG GCATCGGTCA GGGTGTGTTC CTGCAGGAAG CTGCGGATGT


 


201
CTTCGGGCAA AGTGTAGTCG CGGGCGACGG CGGCAAAGCG GGCATCGGTT


 


251
TGCAGGCGGT CGAGCAGGGT TTGGTTTTTG TCCAACTTCA TGCCTGCTTC


 


301
TTTTTCTTCG GCGGTGGCGC GGACAAACTG GTCGTAAATT TCGGCATAAA


 


351
GCATATCGTT CGGGCCTTCA AAAATCGTGA AGGGGCGGAT GTCGATAGCG


 


401
ATATTGCCGG CGGTGTGTCC GCGTTCAAAA CCCTTCGCGC CCAAGAGTTT


 


451
TTGCAACATT TGCGCGGCGG CGTAAGTGTA TTCCGTGGCG AGGGTTTTGA


 


501
CGATGTTCGC CTCCATCAGT TGATGGGCGA CGGGTGCAAC GGGCGAAACG


 


551
GAATGGCAGA CGTAGCGGTA AAGAATCTCG GAAACCTGAT GGCGGCGCCG


 


601
GATTTCGCGG CGTTCGTAAT CGACGAATCT GATGTCGTTG CGGACGTATC


 


651
GTTCCAGGTT TTCAAGGGTG TATTCCATAA TGCCGTGCGT CATGCCGATC


 


701
AGTTGCAGGC GGCTGCGGAT AAAGATGTTT TGGAACGCGC GCAAACCGGC


 


751
AGCGTCGCTC TGGGAGAGTT TCATCACGGC GGTTGCAGGC ATTTCGGCAT


 


801
CGATGCGGTT GACGGCGTAA CGGACGGCGC GCAAGCCTTC GGATGCGAGG


 


851
GTTTCGCAGC GGATGTATGT TTTGGGGACG AGCAGCAGGT CGATGACTTT


 


901
GGCGAGTTTG CCGTTTTTGC GCTCTTTGGC GGCAACGAGG AGGAAGTCGC


 


951
TTTGCGAGTT GCCCTGCCAG TATTTCGCGG CGTTGACGTA AATGGTTTGT


 


1001
CCGTCGGTAT ATTCGTAGTA AGACTGCATT TCTCGGGCAA TCGCCGCGCC


 


1051
GGAGGTTTCG GGTTCGGTAA CGCCTAAACC GCCGCCCTCG CCTTTGAAAA


 


1101
CCATGTCCAA ACCCTGTGCG ATTTGCGCTT CATCGCCGAA CTCTTGCAGT


 


1151
GGCTGCAACA CCAGCGCGCC TTCGATGCCG GTACGCAGCG TAACGGGCAC


 


1201
GCCGTAATGC CCCGCAATCC G






This corresponds to the amino acid sequence <SEQ ID 2062; ORF 642.a>:









a642.pep Length: 407










1
ACRRICPLSA ISAVQYVFAD VVQQEGCGVF VFRLYEDKES GDDFADKDFL



 


51
QGAGIGQGVF LQEAADVFGQ SVVAGDGGKA GIGLQAVEQG LVFVQLHACF


 


101
FFFGGGADKL VVNFGIKHIV RAFKNREGAD VDSDIAGGVS AFKTLRAQEF


 


151
LQHLRGGVSV FRGEGFDDVR LHQLMGDGCN GRNGMADVAV KNLGNLMAAP


 


201
DFAAFVIDES DVVADVSFQV FKGVFHNAVR HADQLQAAAD KDVLERAQTG


 


251
SVALGEFHHG GCRHFGIDAV DGVTDGAQAF GCEGFAADVC FGDEQQVDDF


 


301
GEFAVFALFG GNEEEVALRV ALPVFRGVDV NGLSVGIFVV RLHFSGNRRA


 


351
GGFGFGNA*T AALAFENHVQ TLCDLRFIAE LLQWLQHQRA FDAGTQRNGH


 


401
AVMPRNP






m642/a642 95.8% identity in 407 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2063>:










g643.seq




1
ATGGTGTTGC CTTTGATGTT GTTGGCGACA ATCAGgTcgg CTACGCTGAc


 


51
gttgtancGt TTGGcaATGt tGaaCAgggt gtcgccTTCT ACAACGCGGT


 


101
GGATGCTGGC ATGGagcGGG GAGGTTTCGG CTTCGCCGTC GGCAGCTTTG


 


151
GCTACGCGCG TTTCCAAACG TGCCCGGCGT TtgCCGTCGG CGGCAACGGT


 


201
ATGTTGCGGA GATGAGGAAA TGTTGTGTTC GGCAACTGTG TCAGGCGTGC


 


251
CGATGACGGC GGagaTGGTT TCTTCAGCCT GCCGGCGCag gTTGTTTCGG


 


301
GCAACAAGCT GCATGAGTTC GTCTGCCGCC TGCATGTCGT TTGGGGGGAt


 


351
GACCTGCGCg aGTGtTGCGG TTTGGGTTTC agacgGCATG GCAGTCTGTT


 


401
TTTcggTTTG a






This corresponds to the amino acid sequence <SEQ ID 2064; ORF 643>:










g643.pep




1
MVLPLMLLAT IRSATLTLXR LAMLNRVSPS TTRWMLAWSG EVSASPSAAL


 


51
ATRVSKRARR LPSAATVCCG DEEMLCSATV SGVPMTAEMV SSACRRRLFR


 


101
ATSCMSSSAA CMSFGGMTCA SVAVWVSDGM AVCFSV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2065>:










m643.seq




1
ATGGTGTTGC CTTTGATGTT GTTGGCGACA ATCAGGTCGG CTACACTGAC


 


51
GTTGTAGCGT TTGGCAATGT TGAACAGGGT GTCGCCTTCT ACAACGCGGT


 


101
GGATGCTGGC ATGGAGCGGG GAGATTTCGG CTTCGCCGTC GGCAGCTTTG


 


151
GCTACGCGCG TTTCCAAACG TACCCGGCGT TTGCCGTCGG CGGCAGCGGT


 


201
ATGTTGCGGA GATGCGGAAA TTTTGTGTTC GGCAACTGTG TCAGGCGTGC


 


251
CGATGACGGC GGAGATGGTT TCTTCAGCCT GTCGGCGCAG GTTGTTTCGG


 


301
GCAACAAGCT GCATGAGTTC GTCTGCCGCC TGCATGTCGT TTTGGGGGAT


 


351
GATCTGCGCG AGTGTTGCGG TTTGGGTTTC AGACGGCATG GCGGTCTGTT


 


401
TTTCGGTTTG A






This corresponds to the amino acid sequence <SEQ ID 2066; ORF 643>:










m643.pep




1
MVLPLMLLAT IRSATLTL*R LAMLNRVSPS TTRWMLAWSG EISASPSAAL


 


51
ATRVSKRTRR LPSAAAVCCG DAEILCSATV SGVPMTAEMV SSACRRRLFR


 


101
ATSCMSSSAA CMSFWGMICA SVAVWVSDGM AVCFSV*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 643 shows 94.9% identity over a 136 aa overlap with a predicted ORF (ORF643.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2067>:










a643.seq




1
ATGGTGTTGC CTTTGATGTT GTTGGCGACA ATCAGGTCGG CTACACTGAC


 


51
GTTGTAGCGT TTGGCAATGT TGAACAGGGT GTCGCCTTCT ACAACGCGGT


 


101
GGATGCTGGC ATGGAGCGGG GAGATTTCGG CTTCGCCGTC GGCAGCTTTG


 


151
GCTACGCGCG TTTCCAAACG TACCCGGCGT TTGCCGTCGG CGGCAACGGT


 


201
ATGTTGCGGA GATGAGGAAA TGTTGTGTTC GGCAACTGTG TCAGGCGTGC


 


251
CGATGACGGC AGAGATGGTT TCTTCAGCCT GTCGGCGCAG GTTGTTTCGG


 


301
GCAACAAGCT GCATGAGTTC GTCTGCCGCC TGCATGTCGT TTTGGGGGAC


 


351
GATCTGCGCG AGTGTTGCGG TTTGGGTTTC AGACGGCATG GCGGTCTGTT


 


401
TTTCGGTTTG A






This corresponds to the amino acid sequence <SEQ ID 2068; ORF 643.a>:










a643.pep




1
MVLPLMLLAT IRSATLTL*R LAMLNRVSPS TTRWMLAWSG EISASPSAAL


 


51
ATRVSKRTRR LPSAATVCCG DEEMLCSATV SGVPMTAEMV SSACRRRLFR


 


101
ATSCMSSSAA CMSFWGTICA SVAVWVSDGM AVCFSV*






m643/a643 97.1% identity in 136 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2069>:










g644.seq




1
ATGCCGTCTG AAAGGccgGC GGATTGTTGC CCGGTGCACT TTGTGGTAAA


 


51
GTTTAGAAAA TTAACTCTAA ACTGTGGCAG GCGGTTTGAC CGGCCGCCGA


 


101
TTAATGGGAA CCGACAGAGG AAGCCGATGA TACACACCGA ACCGAGCGCG


 


151
CAGCCGTCAA CCATGGACAC GGCTGCTTTT TTAAagcaca tcgaatCCGC


 


201
ATTcCCCCGC ATTTTTTCAG ACGGCATCGA CCTGATGCGA TACCTGCCCG


 


251
AAGACAAATG GCTTGCCTTG AAGCAGGCGG GTTTGCTGTT GCCCTTCCTC


 


301
GACAAAAAAC ACGGCGGGCG CAAGGGCAGT CAGTTTGAAA TCCAAGAAGT


 


351
CCTAAGGATT GCGGGGCATT ACGGCGTGCC CGTTACGCTG CGTACCGGCA


 


401
TCGAAGGCGC GCTGGTGTTG CAGCCTCTGC AAGagttcgg cggcgaagcG


 


451
CAAGTCGCAC AAGGTTTGGA CATGATTTTC AAaggcgaaa gccgccgttt


 


501
gggcgTtacc gaacccgaAa cctccggcgc gGcgaTTGCA CGCGAAAtgc


 


551
agtcctgcta cgaatatacc gacgaacaAA CCATTTACGT caaCGCCGCG


 


601
AAATACTGGC AGGGCAATTC GCAAAGCGAC TTCCTcctcg ttgccgccaa


 


651
agagcgcaaa aacGGcaaac tcgccaaagt CATCGACCTG CTGCTCGTCC


 


701
CCAAAACATA CATCCGCTGC GAAACCCTCG CATCCGAAGG CCTGCGCGCC


 


751
GTCCGTTACG CCGTCAACCG CATCGATGCC GAAATGCCTG CAACCGCCGT


 


801
GATGAAACTC TCCCGGGGCG ACGCTGCCGG TTTGCGCGCG TTCCAAAACA


 


851
TCTTTATCCG CAGCCGCCTG CAACTGATCG GCATGACGCA CGGCATTATG


 


901
GAATACATCC TTGACAACCT GAACCGATAT GTCCGCAACG ATATCAGATT


 


951
CGTCGATTAC GAACGCCGCG AAATCCAACG CCGCCATCAG GTTTCCGAAA


 


1001
TCCTTTACCG CTACGTCTGC CATTCCGTTT CGcccgtcgC GCccgTCGCC


 


1051
CATCAATTGA TGGAGGCGAA catcgTCAAA ACcctCGCCA CGGAATACAC


 


1101
TTAcgcCGCC GCGCAAATGT TGCAAAAACT CTTGGGCGCG AAGGGTTTTG


 


1151
AACGCGGACA CCCAGCCGGC AATATCGCCA TCGATATCCG CCCCTTCACG


 


1201
ATTTTTGAAG GCCCGAACGA TATGCTTTAT GCCGAAATTT ACGACCAGTT


 


1251
CGTCCGCGCC ACCGCCGAAG AAAAAGAAGC AGGCATTAAG TTGGACAAAA


 


1301
accaaaCCCT Gctcgacgcc gtgCAAaccg atGTCcgctt tgCCGCCGTT


 


1351
GCCcgcGacT ACGCTTTGCC CGAAGACATC CGCAGCTTCC TGCAGGAACA


 


1401
CACCCTGACC GACGCCTGCG CCCTGCAAAA AGTCTTCATC GGCAAAATCA


 


1451
TCGCCCGACT TTTTGTCTTC GTACAGGAGG AACACGAAGA CACCACAGCC


 


1501
TTCCTGCTGA ACGACATCCG CAAAGATATA TTGGACTGCC GATATTGCGG


 


1551
ATAG






This corresponds to the amino acid sequence <SEQ ID 2070; ORF 644.ng>:










g644.pep




1
MPSERPADCC PVHFVVKFRK LTLNCGRRFD RPPINGNRQR KPMIHTEPSA


 


51
QPSTMDTAAF LKHIESAFPR IFSDGIDLMR YLPEDKWLAL KQAGLLLPFL


 


101
DKKHGGRKGS QFEIQEVLRI AGHYGVPVTL RTGIEGALVL QPLQEFGGEA


 


151
QVAQGLDMIF KGESRRLGVT EPETSGAAIA REMQSCYEYT DEQTIYVNAA


 


201
KYWQGNSQSD FLLVAAKERK NGKLAKVIDL LLVPKTYIRC ETLASEGLRA


 


251
VRYAVNRIDA EMPATAVMKL SRGDAAGLRA FQNIFIRSRL QLIGMTHGIM


 


301
EYILDNLNRY VRNDIRFVDY ERREIQRRHQ VSEILYRYVC HSVSPVAPVA


 


351
HQLMEANIVK TLATEYTYAA AQMLQKLLGA KGFERGHPAG NIAIDIRPFT


 


401
IFEGPNDMLY AEIYDQFVRA TAEEKEAGIK LDKNQTLLDA VQTDVRFAAV


 


451
ARDYALPEDI RSFLQEHTLT DACALQKVFI GKIIARLFVF VQEEHEDTTA


 


501
FLLNDIRKDI LDCRYCG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2071>:










m644.seq




1
ATGCCGTCTG AAAGGTCGGC GGATTGTTGC CCGGCGCACT TTGTGGTAAA


 


51
GTTTAGAAAA TCAACTCTAA ACTGTGGCAG GCGGTTTGAC CGGCCGCCGA


 


101
TTAATGGGAA CCGACAGAGG AAGCCGATGA TACACACCGA ACCGAGCGCG


 


151
CAGCCGTCAA CTATGGACAC GGCTGCTTTT TTAAAGCACA TCGAATCCGC


 


201
ATTCCGCCGC ATTTTTTCAG ACGGTATCGA CCTGATGCGA TACCTGCCCG


 


251
AAGACAAATG GCTTGCCTTG AAGCAGGCGG GTTTGCTGTT GCCCTTCCTC


 


301
GACAAAAAAT ACGGCGGGCG CAAGGGCAGC CAGTTTGAAA TCCAAGAAGT


 


351
CcTGCGGATT GCGGGGCATT ACGGCGTGCC CGTTACGCTG CGTACCGGCA


 


401
TCGAAGGCGC GCTGGTGTTG CAGCCACTGC AAGAGTTCGG CGATGAAGCG


 


451
CAAGTCGCGC AAGGTTTGGA GATGATTTTC AAAGGCGAGG GCGGCGGTTT


 


501
GGGTGTTACC GAACCCGAAA CCTCCGGCGC GGCGATTGCA CGCGAAATGC


 


551
AGTCCTACTA CGAATATATC GACGGACAAA CCATTTACGT CAACGCCGCG


 


601
AAATACTGGC AGGGCAACTC GCAAAGCGAC TTCCTCCTCG TTGCCGCCAA


 


651
AGAGCGCAAA AACGGCAAAC TCGCCAAAGT CATCGACCTG CTGCTCGTCC


 


701
CCAAAACATA CATCCGCTGC GAAACCCTCG CATCCGAAGG CTTGCGCGCC


 


751
GTCCGTTACG CCGTCAACCG CATCGATGCC GAAATGCCTG CAACCGCCGT


 


801
GATGAAACTC TCCCAGAGCG ACGCTGCCGG TTTGCGCGCG TTCCAAAACA


 


851
TCTTTATCCG CAGCCGCCTG CAACTGATCG GCATGACGCA CGGCATTATG


 


901
GAATACATCC TTGAAAATCT GGAACGATAC GTCCGCAACG ACATCAAATT


 


951
CGTCGATTAC GAACGCCGCG AAATCCGGCG CCGCCATCAG GTTTCCGAGA


 


1001
TTCTTTACCG CTACGTCTGC CATTCCGTTT CGCCTGTTGC CCCCGTCGCC


 


1051
CATCAGCTGA TGGAGGCGAA CATCGTCAAA ACCCTCGCCA CGGAATACAC


 


1101
TTACGCCGCC GCGCAAATGT TGCAAAAACT CTTGGGTGCG AAGGGTTTTG


 


1151
AACGCGGACA CACCGCCGGC AATATCGCTA TCGACATCCG CCCCTTCACG


 


1201
ATTTTTGAAG GCCCGAACGA TATGCTTTAT GCCGAAATTT ACGACCAGTT


 


1251
TGTCCGCGCC ACCGCCGAAG AAAAAGAAGC AGGCATGAAG TTGGACAAAA


 


1301
ACCAAACCCT GCTCGACCGC CTGCAAACCG ATGCCCGCTT TGCCGCCGTC


 


1351
GCCCGCGACT ACACTTTGCC TGAAGACATC CGCAGCTTCC TGCAGGAACA


 


1401
CACCCTGACC GATGCCTGCG CCCTGCAAAA AGTCTTTATC GGCAAAATCA


 


1451
TCGCCCGACT CTTTGTCTTC GTACAGGCGA AACACGAAGA CACCGCAGCC


 


1501
TTCCTGCTGA ACGACATCCG CAAAGATATA TTGGACTGCC GATATTGCGG


 


1551
GTAG






This corresponds to the amino acid sequence <SEQ ID 2072; ORF 644>:










m644.pep




1
MPSERSADCC PAHFVVKFRK STLNCGRRFD RPPINGNRQR KPMIHTEPSA


 


51
QPSTMDTAAF LKHIESAFRR IFSDGIDLMR YLPEDKWLAL KQAGLLLPFL


 


101
DKKYGGRKGS QFEIQEVLRI AGHYGVPVTL RTGIEGALVL QPLQEFGDEA


 


151
QVAQGLEMIF KGEGGGLGVT EPETSGAAIA REMQSYYEYI DGQTIYVNAA


 


201
KYWQGNSQSD FLLVAAKERK NGKLAKVIDL LLVPKTYIRC ETLASEGLRA


 


251
VRYAVNRIDA EMPATAVMKL SQSDAAGLRA FQNIFIRSRL QLIGMTHGIM


 


301
EYILENLERY VRNDIKFVDY ERREIRRRHQ VSEILYRYVC HSVSPVAPVA


 


351
HQLMEANIVK TLATEYTYAA AQMLQKLLGA KGFERGHTAG NIAIDIRPFT


 


401
IFEGPNDMLY AEIYDQFVRA TAEEKEAGMK LDKNQTLLDR LQTDARFAAV


 


451
ARDYTLPEDI RSFLQEHTLT DACALQKVFI GKIIARLFVF VQAKHEDTAA


 


501
FLLNDIRKDI LDCRYCG*






m644/g644 94.6% identity in 517 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2073>:










a644.seq




1
ATGCCGTCTG AAAGGTCGGC GGATTGTTGC CCGGCGCACT TTGTGGTAAA


 


51
GTTTAGAAAA TCAACTCTAA ACTGTGGCAG GCGGTTTGAC CGGCCGCCGA


 


101
TTAATGGGAA CCGACAGAGG AAGCCGATGA TACACACCGA ACCGAGCGCG


 


151
CAGCCGTCAA CTATGGACAC GGCTGCTTTT TTAAAGCACA TCGAATCCGC


 


201
ATTCCGCCGC ATTTTTGCAG ACGGTATCGA CCTGATGCGA TACCTGCCCG


 


251
AAGACAAATG GCTTGCCTTG AAGCAGGCGG GTTTGCTGTT GCCCTTCCTC


 


301
GACAAAAAAT ACGGCGGGCG CAAGGGCAGC CAGTTTGAAA TTCAGGAAGT


 


351
CTTGCGGATT GCGGGGCATT ACGGCGTGCC CGTTANNNNN NNNNNNNNNN


 


401
NNGAAGGCGC GCTGGTGTTG CAGCCACTGC AAGAGTTCGG CGATGAAGCG


 


451
CAAATCGCAC AGGGTTTGGA CATGGTTTTC AAAGGCGAGG GCGGCGGTTT


 


501
AGGCGTTACC GAACCCGAAA CCTCCGGCGC GGCGATTGCC CGAGAAATGC


 


551
AGTCTTACTA CGAATATACC GACGGACAAA CCATTTACGT CAACGCCGCG


 


601
AAATACTGGC AGGGCAACTC GCAAAGCGAC TTCCTCCTCG TTGCCGCCAA


 


651
AGAGCGCAAA AACGGCAAAC TCGCCAAAGT CATCGACCTG CTGCTCGTCC


 


701
CCAAAACATA CATCCGCTGC GAAACCCTCG CATCCGAAGG CTTGCGCGCC


 


751
GTCCGTTACG CCGTCAACCG CATCGATGCC GAAATGCCTG CAACCGCCGT


 


801
GATGAAACTC TCCCAGAGCG ACGCTGCCGG TTTGCGCGCG TTCCAAAACA


 


851
TCTTTATCCG CAGCCGCCTG CAACTGATCG GCATGACGCA CGGCATTATG


 


901
GAATACACCC TTGAAAACCT GGAACGATAC GTCCGCAACG ACATCAGATT


 


951
CGTCGATTAC GAACGCCGCG AAATCCGGCG CCGCCATCAG GTTTCCGAGA


 


1001
TTCTTTACCG CTACGTCTGC CATTCCGTTT CGCCCGTTGC ACCCGTCGCC


 


1051
CATCAACTGA TGGAGGCGAA CATCGTCAAA ACCCTCGCCA CGGAATACAC


 


1101
TTACGCCGCC GCGCAAATGT TGCAAAAACT CTTGGGCGCG AAGGGTTTTG


 


1151
AACGCGGACA CACCGCCGGC AATATCGCTA TCGACATCCG CCCCTTCACG


 


1201
ATTTTTGAAG GCCCGAACGA TATGCTTTAT GCCGAAATTT ACGACCAGTT


 


1251
TGTCCGCGCC ACCGCCGAAG AAAAAGAAGC AGGCATGAAG TTGGACAAAA


 


1301
ACCAAACCCT GCTCGACCGC CTGCAAACCG ATGCCCGCTT TGCCGCCGTC


 


1351
GCCCGCGACT ACACTTTGCC CGAAGACATC CGCAGCTTCC TGCAGGAACA


 


1401
CACCCTGACC GATGCCTGCG CCCTGCAAAA AGTCTTTATC GGCAAAATCA


 


1451
TCGCCCGACT CTTTGTCTTC GTACAGGCGG AACACGAAGA CACCGCAGCC


 


1501
TTCCTGCTGA ACGACATCCG CAAAGACATA TTGGACTGCC GATATTGCGG


 


1551
ATAG






This corresponds to the amino acid sequence <SEQ ID 2074; ORF 644.a>:










a644.pep




1
MPSERSADCC PAHFVVKFRK STLNCGRRFD RPPINGNRQR KPMIHTEPSA


 


51
QPSTMDTAAF LKHIESAFRR IFADGIDLMR YLPEDKWLAL KQAGLLLPFL


 


101
DKKYGGRKGS QFEIQEVLRI AGHYGVPVXX XXXXEGALVL QPLQEFGDEA


 


151
QIAQGLDMVF KGEGGGLGVT EPETSGAAIA REMQSYYEYT DGQTIYVNAA


 


201
KYWQGNSQSD FLLVAAKERK NGKLAKVIDL LLVPKTYIRC ETLASEGLRA


 


251
VRYAVNRIDA EMPATAVMKL SQSDAAGLRA FQNIFIRSRL QLIGMTHGIM


 


301
EYTLENLERY VRNDIRFVDY ERREIRRRHQ VSEILYRYVC HSVSPVAPVA


 


351
HQLMEANIVK TLATEYTYAA AQMLQKLLGA KGFERGHTAG NIAIDIRPFT


 


401
IFEGPNDMLY AEIYDQFVRA TAEEKEAGMK LDKNQTLLDR LQTDARFAAV


 


451
ARDYTLPEDI RSFLQEHTLT DACALQKVFI GKIIARLFVF VQAEHEDTAA


 


501
FLLNDIRKDI LDCRYCG*






m644/a644 97.3% identity in 517 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2075>:










g645.seq




1
ATGATGATGG TGTTGGCGTT GGGGATGTCG ATGCCGGTTT CGATGATGGT


 


51
GGAACAGAGC AACACATTGA ATCTTTGCTG CAAAAAGTCG CGCATGACTT


 


101
GTTCCAGCTC GCGCTCACGC AGTTGTCCGT GCGCCACGCC GATACGGGCT


 


151
TCGGGCAGCA GGGTTTCCAG CCGCTCGCGC ATATTCTCAA TCGTATCTAC


 


201
TTCATTGTGC AGGAAAAata cCTGTCCTCC GCGTTTGAGT TCGCGCAACA


 


251
CGGCTTCGCG CACGCTGCCT TCGCTGAACG GTTTGACAAA GGTTTTCACG


 


301
GCGAGGCGGC GGCTCGGTGC AGTGGTAATC AGCGAGAAGT CGCGCAGACC


 


351
TTCGAGCGCC ATGCTGAGGG TGCGCGGAAT CGGCGTGGCG GTCATGGTTA


 


401
GGATGTCGAC ATTGGCGCGC AGGCGTTTGA GCTGCTCTTT CTGTCGCACG


 


451
CCGAAGCGGT GTTCTTCATC GATAATCAAT AAACCTAAGT TTTTGAATTT


 


501
TATGTCGTCC TGCACCAATT TGTGCGTACC GATAACGATA TCGACAGTAC


 


551
CGTCCGCCAT GCCTTCGAGC GTGGCTTTGG TGGCTTTGCT GTTGTTGAAA


 


601
CGCGAAAGGC TGGCGACTTT CACGGGGAAA TCGGCGAAAC GGTCGGCGAA


 


651
GTTTTGCGCG TGCTGCTCGA CCAGAAGCGT GGTCGGGGCG AGTACGGCGA


 


701
CCTGTTTGCC GCCCATCACC GCCACAAACG CGGCGCGAAG GGCGACTTCG


 


751
GTTTTGCCGA AACCGACATC GCCGCACACA AGTCGGTCCA TCGGCTTCGC


 


801
CTGCGTCAAA TCTTTAATCA CGGcggcgat ggcggcggcC TGGTCTTCGG


 


851
TTTCCTCGTA G






This corresponds to the amino acid sequence <SEQ ID 2076; ORF 645.ng>:










g645.pep




1
MMMVLALGMS MPVSMMVEQS NTLNLCCKKS RMTCSSSRSR SCPCATPIRA


 


51
SGSRVSSRSR IFSIVSTSLC RKNTCPPRLS SRNTASRTLP SLNGLTKVFT


 


101
ARRRLGAVVI SEKSRRPSSA MLRVRGIGVA VMVRMSTLAR RRLSCSFCRT


 


151
PKRCSSSIIN KPKFLNFMSS CTNLCVPITI STVPSAMPSS VALVALLLLK


 


201
RERLATFTGK SAKRSAKFCA CCSTRSVVGA STATCLPPIT ATNAARRATS


 


251
VLPKPTSPHT SRSIGFACVK SLITAAMAAA WSSVSS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2077>:










m645.seq




1
ATGATGATGG TGTTGGCGTT GGGGATATCG ATACCGGTTT CGATGATGGT


 


51
GGAACAGAGC AACACGTTAA ATCGTTGCTG CAAAAAGTCG CGCATGACTT


 


101
GTTCCAGCTC GCGCTCGCGC AGTTGTCCGT GCGCCACGCC GATGCGGGCT


 


151
TCGGGCAGCA GGGTTTCCAG CCGCTCGCGC ATATTTTCAA TCGTATCTAC


 


201
TTCATTGTGC AGGAAAAATA CCTGTCCTCC GCGTTTGAGT TCGCGCAACA


 


251
CGGCTTCGCG CACGCTGCCT TCGCTAAAGG GTTTGACAAA GGTTTTGACG


 


301
GCGAGGCGGC GGCTGGGCGC GGTGGTAATC AGCGAGAAGT CGCGCAGTCC


 


351
TTCCAACGCC ATACTTAAAG TACGCGGAAT CGGCGTGGCG GTCATGGTAA


 


401
GGATATCAAC ATTGGCGCGC AGGCGTTTGA GCTGCTCTTT CTGACGCACG


 


451
CCGAAGCGGT GTTCTTCGTC GATAATCACT AAACCTAAGT TTTTGAATTT


 


501
GATGTCGTCC TGCACCAGTT TGTGCGTACC GATAACAATA TCGACCGTGC


 


551
CGTCTGCCAT GCCTTCCAGC GCGGCTTTGG TGGCTTTGCT GTTGTTGAAA


 


601
CGCGAAAGGC TGGCGACTTT CACGGGGAAA TCGGCGAAAC GGTCGGCGAA


 


651
GTTTTGCGCG TGCTGCTCGA CCAAAAGCGT GGTCGGAGCA AGTACGGCGA


 


701
CCTGTTTGCC GCCCATCACC GCCACAAACG CGGCGCGCAG GGCGACTTCG


 


751
GTTTTGCCGA AGCCGACATC GCCGCACACA AGGCGATCCA TCGGCTTCGC


 


801
TTGCGTCAAA TCTTTAATCA CGGCGGCGAT GGCGGCGGCC TGGTCTTCGG


 


851
TTTCCTCGTA G






This corresponds to the amino acid sequence <SEQ ID 2078; ORF 645>:










m645.pep




1
MMMVLALGIS IPVSMMVEQS NTLNRCCKKS RMTCSSSRSR SCPCATPMRA


 


51
SGSRVSSRSR IFSIVSTSLC RKNTCPPRLS SRNTASRTLP SLKGLTKVLT


 


101
ARRRLGAVVI SEKSRSPSNA ILKVRGIGVA VMVRISTLAR RRLSCSF*RT


 


151
PKRCSSSIIT KPKFLNLMSS CTSLCVPITI STVPSAMPSS AALVALLLLK


 


201
RERLATFTGK SAKRSAKFCA CCSTKSVVGA STATCLPPIT ATNAARRATS


 


251
VLPKPTSPHT RRSIGFACVK SLITAAMAAA WSSVSS*






m645/g645 93.7% identity in 286 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2079>:










a645.seq




1
ATGATGATGG TGTTGGCGTT GGGAATGTCG ATACCGGTTT CGATGATGGT


 


51
GGAACAGAGC AACACGTTAA ATCGTTGCTG CAAAAAGTCG CGCATGACTT


 


101
GTTCCAGCTC GCGCTCGCGC AGTTGTCCGT GCGCCACGCC GATGCGGGCT


 


151
TCGGGCAGCA GGGTTTCCAG CCGCTCACGC ATGTTTTCGA TGGTATCCAC


 


201
TTCATTGTGC AGGAAAAATA CTTGCCCGCC GCGTTTGAGT TCGCGCAATA


 


251
CGGCTTCGCG CACGCTGCCT TCGCTGAACG GTTTGACAAA GGTTTTGACG


 


301
GCGAGGCGGC GGCTGGGCGC AGTGGTAATC AGCGAGAAGT CGCGCAGTCC


 


351
TTCCAGCGCC ATACTTAAAG TACGCGGAAT CGGCGTAGCG GTCATGGTAA


 


401
GGATGTCGAC ATTGGCGCGC AGGCGTTTGA GCTGCTCTTT CTGACGCACG


 


451
CCGAAGCGGT GTTCTTCGTC GATAATCACT AAACCTACGT TTTTGAATTT


 


501
TATGTCGTCC TGCACCAGTT TGTGCGTACC GATAACAATA TCGACCGTGC


 


551
CGTCCGCCAT GCCTTCCAGC GCGGCTTTGG TGGCTTTGCT GTTGTTGAAA


 


601
CGCGAAAGGC TGGCGACTTT CACGGGGAAA TCGGCGAAGC GGTCGGCAAA


 


651
ATTTTGCGCG TGCTGCTCGA CCAGAAGCGT GGTCGGTGCG AGTACGGCAA


 


701
CTTGTTTGCC ACCCATTACC GCCACAAACG CGGCGCGCAG GGCGACTTCG


 


751
GTTTTGCCGA AACCGACATC GCCGCACACG AGGCGGTCCA TCGGCTTCGC


 


801
CTGCGTCAAA TCTTTAATCA CGGCGGCGAT GGCGGCTGCC TGGTCTTCGG


 


851
TTTCTTCGTA G






This corresponds to the amino acid sequence <SEQ ID 2080; ORF 645.a>:










a645.pep




1
MMMVLALGMS IPVSMMVEQS NTLNRCCKKS RMTCSSSRSR SCPCATPMRA


 


51
SGSRVSSRSR MFSMVSTSLC RKNTCPPRLS SRNTASRTLP SLNGLTKVLT


 


101
ARRRLGAVVI SEKSRSPSSA ILKVRGIGVA VMVRMSTLAR RRLSCSF*RT


 


151
PKRCSSSIIT KPTFLNFMSS CTSLCVPITI STVPSAMPSS AALVALLLLK


 


201
RERLATFTGK SAKRSAKFCA CCSTRSVVGA STATCLPPIT ATNAARRATS


 


251
VLPKPTSPHT RRSIGFACVK SLITAAMAAA WSSVSS*






m645/a645 96.9% identity in 286 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2081>:










g647.seq




1
ATGCAAAGGC TCGCCGCAGA CGGCATCCAA ATCTTTTTTG TAGGTGTCGA


 


51
TGGGCAGTTT GCCTTGCGAA TAAACGGTTT GGTTAAAGAG CGTGCACGCT


 


101
CCGTATTCTT TGGCAAGGTT TGCCGATGCT TTGAGCAGGT AATACTGTAT


 


151
GGCTTCAAAG GTACGGTGGG TCAGACCGAG CGCGGAACCG TCGCTGTAGC


 


201
GGACACCGTT TTTCGCCAGA TAGTAGGCGT AGTTGATGAC ACCGATGCCG


 


251
AGCGAACGGC GGTCCATAGT AGAGGTACGC GCGGCTTCTA CCGGATATCC


 


301
CTGATAATCT AA






This corresponds to the amino acid sequence <SEQ ID 2082; ORF 647.ng>:










g647.pep




1
MQRLAADGIQ IFFVGVDGQF ALRINGLVKE RARSVFFGKV CRCFEQVILY


 


51
GFKGTVGQTE RGTVAVADTV FRQIVGVVDD TDAERTAVHS RGTRGFYRIS


 


101
LII*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2083>:










m647.seq




1
ATGCAAAGGC TCGCCGCAGA CGGCATCCAA ATCTTTTTTG TAAGTGTCGA


 


51
TGGGCAGTTT GCCTTGCGAA TAAACGGTTT GGTTAAAGAG CGTGCACGCA


 


101
CCGTATTCTT TGGCAAGGTT TGCCGATGCT TTGAGCAGGT AATACTGTAT


 


151
GGCTTCAAAG GTACGGTGGG TCAGACCGAG CGCGGAACCG TCGCTGTAGC


 


201
GGACACCGTT TTTCGCCAGA TAATAAGCAT AGTTAATCAC GCCGATGCCG


 


251
AGCGAACGGC GGCCCATAGT AGAGGTACGC GCGGCTTCTA CCGGATATCC


 


301
CTGATAATCT AA






This corresponds to the amino acid sequence <SEQ ID 2084; ORF 647>:










m647.pep




1
MQRLAADGIQ IFFVSVDGQF ALRINGLVKE RARTVFFGKV CRCFEQVILY


 


51
GFKGTVGQTE RGTVAVADTV FRQIISIVNH ADAERTAAHS RGTRGFYRIS


 


101
LII*






m647/g647 91.3% identity in 103 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2085>:










a647.seq




1
GTGCAAAGGC TCGTTACACA CAGCGTCCAA GTCTTTTTTG TAGGTGTCGA


 


51
TGGGCAGTTT GCCTTGCGAA TAAACGGTTT GGTTAAAGAG CGTGCACGCA


 


101
CCGTATTCTT TGGCAAGGTT TGCCGATGCT TTGAGCAGGT AATACTGTAT


 


151
GGCTTCAAAG GTACGGTGGG TCAGACCGAG CGCGGAGCCG TCGCTGTAGC


 


201
GGACACCGTT TTTCGCCAAA TAATACGCAT AGTTGATCAC GCCGATACCG


 


251
AGCGAACGGC GGCCCATAGT GGAGGTACGC GCGGCTTCTA CCGGATATCC


 


301
CTGATAATCT AA






This corresponds to the amino acid sequence <SEQ ID 2086; ORF 647.a>:










a647.pep




1
VQRLVTHSVQ VFFVGVDGQF ALRINGLVKE RARTVFFGKV CRCFEQVILY


 


51
GFKGTVGQTE RGAVAVADTV FRQIIRIVDH ADTERTAAHS GGTRGFYRIS


 


101
LII*






m647/a647 87.4% identity in 103 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2087>:










g648.seq




1
ATGAACAGGC GCAACGCGCG GATCGAACGG GCTGTGCGTA TTGCAGTGAT


 


51
CGACGTTTTG AATGTAGATG CGCCCGGTCC CGGCACGCTC CTGCATCAGC


 


101
GTGGAAAACA GGTCGGCAGC CGGAATGATA CGCTTGCGTA TGTTCGGGTC


 


151
TTGCTCGTAT TTCGTATAGA GCCGCTCAAA TTCGTCTTGG TCGGCAAAAA


 


201
ACGCTTCGTA CAACCCCGAA ACCTCGTTGG GCGAAAACAG CGTAATGTTG


 


251
CCGCCCTTAA TCAGGCGGGT GTACAGCAGG CGGTTGATTT GCACGCCATA


 


301
ATCAAGCTGG CGGATACGGT TGTCTTCCAC GCCCCGGTTG TTTTTCAACA


 


351
CCAGCAGGCT TTCGGCTTCA ATATGCCACA AGGGGTAGAA CAAGGTTGCC


 


401
GCGCCGCCGC GCACGCCACC TTGCGAACAA GATTTGACCG CCGCCTGAAA


 


451
CATCTTAAAG AAGGGAATGC AGCCGGTATG CCGGGCTTCA CCGCCCCGGA


 


501
TTTCGCTGTC CAGCCCGCGG ATACGTCCGG CATTGATGCC GATGCCCGCG


 


551
CGTTGGGAAA CGTATTTCAC AATCGCGCTG GTAGTGGCAT TGATGGAATC


 


601
CAAACTATCG TCGCATTCAA TCAGCACACA GCTTGA






This corresponds to the amino acid sequence <SEQ ID 2088; ORF 648.ng>:










g648.pep




1
MNRRNARIER AVRIAVIDVL NVDAPGPGTL LHQRGKQVGS RNDTLAYVRV


 


51
LLVFRIEPLK FVLVGKKRFV QPRNLVGRKQ RNVAALNQAG VQQAVDLHAI


 


101
IKLADTVVFH APVVFQHQQA FGFNMPQGVE QGCRAAAHAT LRTRFDRRLK


 


151
HLKEGNAAGM PGFTAPDFAV QPADTSGIDA DARALGNVFH NRAGSGIDGI


 


201
QTIVAFNQHT A*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2089>:










m648.seq




1
ATGAACAGGC GCGACGCGCG GATCGAACGG GCTGTGCGTA TTGCAGTGAT


 


51
CGACGTTTTG AATGTAGATG CGCCCGGTTC CGGCACGCTC CTGCATCAGC


 


101
GTGGAAAACA GGTCGGCAGC CGGAATGATG CGCTTGCGGA TATCAGGGTC


 


151
TTGCTCGTAT TTCGTATAGA GCCGCTCAAA TTCGTCTTGG TCGGCAAAAA


 


201
ACGCTTCGTA CAATCCCGGA ACCTCGTTGG GCGAAAACAG CGTAATGTTG


 


251
CCGCCCTTAA TCAGGCGGGT GTACAGCAGG CGGTTGATTT GCACGCCGTA


 


301
ATCAAGCTGA CGGATACGGT TGTCTTCCAC ACCGCGGTTG TTTTTCAACA


 


351
CCAGCAGGCT TTCGGCTTCG ATATGCCACA AGGGGTAGAA CAAGGTTGCC


 


401
GCGCCGCCGC GCACGCCGCC TTGCGAACAG GATTTGACCG CCGCCTGAAA


 


451
CATTTTAAAG AAGGGAATGC AGCCGGTATG CCGCGCTTCG CCGCCCCGGA


 


501
TTTCGCTGTC CAAACCGCGG ATACGTCCGG CATTGATGCC GATGCCCGCA


 


551
CGCTGGGAAA CGTATTTCAC AATCGCGCTG GTAGTGGCAT TGATGGAATC


 


601
CAAACTATCG TCGCATTCAA TCAGCACACA GCTTGA






This corresponds to the amino acid sequence <SEQ ID 2090; ORF 648>:










m648.pep




1
MNRRDARIER AVRIAVIDVL NVDAPGSGTL LHQRGKQVGS RNDALADIRV


 


51
LLVFRIEPLK FVLVGKKRFV QSRNLVGRKQ RNVAALNQAG VQQAVDLHAV


 


101
IKLTDTVVFH TAVVFQHQQA FGFDMPQGVE QGCRAAAHAA LRTGFDRRLK


 


151
HFKEGNAAGM PRFAAPDFAV QTADTSGIDA DARTLGNVFH NRAGSGIDGI


 


201
QTIVAFNQHT A*






m648/g648 91.5% identity in 211 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2091>:










a648.seq




1
ATGAACAGGC GCAACGCGCG GATCGAACGG GCTGTGCGTA TTGCAGTGAT


 


51
CGACGTTTTG AATGTAGATG CGCCCGGTTC CGGCACGCTC CTGCATCAGC


 


101
GTGGAAAACA GGTCGGCAGC CGGAATGATG CGCTTGCGGA TATCAGGGTC


 


151
TTGCTCGTAT TTCGTATAGA GCCGCTCAAA TTCGTCTTGG TCGGCAAAAA


 


201
ACGCTTCGTA CAATCCCGGA ACCTCGTTGG GCGAAAACAG CGTAATGTTG


 


251
CCGCCCTTAA TCAGGCGGGT GTACAGCAGG CGGTTGATTT GCACGCCGTA


 


301
ATCAAGCTGA CGGATACGGT TGTCTTCCAC GCCCCGGTTG TTTTTCAACA


 


351
CCAGCAGGCT TTCGGCTTCG ATATGCCACA AGGGGTAGAA CAAGGTTGCC


 


401
GCGCCGCCGC GCACGCCACC TTGCGAACAG GATTTGACTG CCGCCTGAAA


 


451
CATTTTAAAG AAGGGAATGC AGCCGGTATG CCGTGCTTCG CCGCCCCGGA


 


501
TTTCGCTGTC CAGTCCGCGG ATACGTCCGG CATTGATGCC GATGCCCGCA


 


551
CGCTGGGAAA CGTATTTCAC AATCGCGCTG GTAGTGGCGT TGATGGAATC


 


601
CAGGCTGTCG TCGCATTCGA TCAATACGCA GCTTGA






This corresponds to the amino acid sequence <SEQ ID 2092; ORF 648.a>:










a648.pep




1
MNRRNARIER AVRIAVIDVL NVDAPGSGTL LHQRGKQVGS RNDALADIRV


 


51
LLVFRIEPLK FVLVGKKRFV QSRNLVGRKQ RNVAALNQAG VQQAVDLHAV


 


101
IKLTDTVVFH APVVFQHQQA FGFDMPQGVE QGCRAAAHAT LRTGFDCRLK


 


151
HFKEGNAAGM PCFAAPDFAV QSADTSGIDA DARTLGNVFH NRAGSGVDGI


 


201
QAVVAFDQYA A*






m648/a648 93.8% identity in 211 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2093>:










g649.seq




1
ATGCTTGCCA TACTGTTGTC TGCAATACTG GGACTGGTAT CAACAACTGC



 


51
CGCTGCCGGT ACGTCAGAAC CCGCCCACCG ACATACCAAA CATATCAGCA


 


101
AGGCAAACAA GCAGATGCTG CACCCCGAAT GCAGGAAATA TTTGGAACGC


 


151
CGTGCCGCGT GGTACCGATC GCAAGGCAAC GTGCAGGAAT TGCGCGAAAA


 


201
CAAAAAGGCG CGCAAAGCAT TCCGCACCCT GCCTTATGCG GAACAGAAAA


 


251
TCCAATGCCG GGCGGCTTAT GAGGCTTTCG ATGATTTCGA CGGCGGCAGG


 


301
TTCCGCCGTT AA






This corresponds to the amino acid sequence <SEQ ID 2094; ORF 649.ng>:










g649.pep




1
MLAILLSAIL GLVSTTAAAG TSEPAHRHTK HISKANKQML HPECRKYLER



 


51
RAAWYRSQGN VQELRENKKA RKAFRTLPYA EQKIQCRAAY EAFDDFDGGR


 


101
FRR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2095>:










m649.seq




1
ATGCTTGCCA TACTGTTGTC TGCAATATTG GGACTGGTAT CGACAACTGC



 


51
CGCTGCCGGT ACGTCAGAAC CCGCCCACCG CGATACCAAA CATATCCGCA


 


101
AGGCAAACAA GCAGATGCTG CACCCCGAAT GCAGGAAATA TTTGGAACGC


 


151
CGTGCCGCGT GGTACCGATC GCAAGGCAAC GTGCAGGAAT TGCGCGAAAA


 


201
CAAAAAGGCG CGCAAAGCAT TCCGCTCCCT GCCTTATGCG GAACAGAAAA


 


251
TCCAATGCCG GGCGGCTTAT GAGGCTTTCG ATGATTTCGA CGGCGGCAGT


 


301
TTCCGCCGTT AA






This corresponds to the amino acid sequence <SEQ ID 2096; ORF 649>:










m649.pep




1
MLAILLSAIL GLVSTTAAAG TSEPAHRDTK HIRKANKQML HPECRKYLER



 


51
RAAWYRSQGN VQELRENKKA RKAFRSLPYA EQKIQCRAAY EAFDDFDGGS


 


101
FRR*






m649/g649 96.1% identity in 103 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2097>:










a649.seq




1
ATGCTTGCCA TACTGTTGTC TGCAATATTG GGACTGGTAT CGACAACTGC



 


51
CGCTGCCGGT ACGTCAGAAC CCGCCCACCG CGATACCAAA CATATCCGCA


 


101
AGGCAAACAA GCAGATGCTG CACCCCGAAT GCAGGAAATA TTTGGAACGC


 


151
CGTGCCGCGT GGTACCGATC GCAAGGCAAC GTGCAGGAAT TGCGCGAAAA


 


201
CAAAAAGGCG CGCAAAGCAT TCCGCTCCCT GCCTTATAAG GAACAGAAAA


 


251
CCCAATGCCG GGCGGCTTAT GAGGCTTTCG ATGATTTCGA CGGCAGCAGG


 


301
TTCCGCCGTT AA






This corresponds to the amino acid sequence <SEQ ID 2098; ORF 649.a>:










a649.pep




1
MLAILLSAIL GLVSTTAAAG TSEPAHRDTK HIRKANKQML HPECRKYLER



 


51
RAAWYRSQGN VQELRENKKA RKAFRSLPYK EQKTQCRAAY EAFDDFDGSR


 


101
FRR*






m649/a649 96.1% identity in 103 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2099>:










g650.seq




1
ATGTCCAAAC TCAAAACCAT CGCCCTGACC GCATCAGGTC TGTCCGTTTG



 


51
TCCGGGTTTC CTATATGCCC AAAACACCTC ATCACACCAA GTCGGTTTAG


 


101
CGATTATGCG GTTAAACTCT TCAATACTCG ACCTGCCACC GACAAAACAA


 


151
TATTTCCAAT CCGGCAGCCT GTGGGACGAG CTGCGCCAAG GCTTCCGGAT


 


201
GGGCGAAGTC AATCCCGAAC TGGTACGCCG CCACGAAAGC AAATTCATCG


 


251
CAAGCCGCAG CTATTTCGAC AGGGTCGTCA ACCGGAGCCG ACCCTATATG


 


301
TACCATATCG CCAACGAAGT CAAAAAACGC AATATGCCCG CCGAAGCCGC


 


351
CCTGCTTCCC TTCATCGAAA GCGCGTTCGT CACCAAAGCC AAATCACACG


 


401
TCGGCGCATC GGGCCTGTGG CAGTTCATGC CCGCTACCGG CAGGCATTAC


 


451
GGCTTGGAAA AAACaccgGT TTACGacggc aggcacGacg TTtacgcaGc


 


501
taccgatgcc gcacTCAACT AtctGcAATA TCTCTAtggA CTGTTCGGCG


 


551
ACTGGCCGCT CGCCTTTGCC GCCTACAACT GGGGTGAAGG CAACGTCGGA


 


601
CGCGCCGTCA ACCGCGCCCG CGACCAAGGG CTCGAACCGA CCTACGAAAA


 


651
CCTGCGTATG CCCAACGAAA CGCGCAACTA TGTCCCCAAG CTGCTCGCCG


 


701
TGCGCAACAT TATTGCCACC CCCCAATCTT TCGGCATGAA TATCAGCGAC


 


751
ATAGACAACA AACCCTATTT TCAGGCAGTC GAACCGGGCC GTCCGCTCGA


 


801
caacGAagcC ATCGCCCGGC TTGCCGGCAT CACGCAAAGC GAGCTGCTCG


 


851
CCCTGAATCC TGCATTCAAC GTCCCCGCgt tcatCCCCAA AAAcaaacgc


 


901
aaacTGCTGC TTCCTGTCGC GTCCGTCCAA ACCTTccaaa gcaACTACCT


 


951
CAACGCCGCA CCCGACAGCC TGTTTTCATG GGAAGTCTAT ACGCCTGCCG


 


1001
CCAAAACCAG CCTGTCCGAC ATCTCGACGG CAACCGGCAT GAGCATTGCC


 


1051
GACATCAAAC GCCTCAACAA CCTGAACGGC AACCTTGTCA ACGCAGGACG


 


1101
CAGCATCCTT GTCGCCAAGA ACGGCAAGAC CCTTCATACG GCATCGGAat


 


1151
ccGTCGTTTC CATCGACATC GACAATACGC CcgacacCTa ccgttccaaT


 


1201
ATGCcggcag gcaCGGTGAA CGTCAGCATt gccCgaatcc aacCCgccgc


 


1251
cgcaCAGACA gcggacatta ccgtcgcacc tttgccgcaa gaaaccgtcc


 


1301
gtacgggaac ccgatcccct tgtccgcaTt accgaacccg ccctTGCGAC


 


1351
AGCCGCAGCg CaacctCAAA ccgAAAAACA GACTGCCATG CcgtctGA






This corresponds to the amino acid sequence <SEQ ID 2100; ORF 650.ng>:










g650.pep




1
MSKLKTIALT ASGLSVCPGF LYAQNTSSHQ VGLAIMRLNS SILDLPPTKQ



 


51
YFQSGSLWDE LRQGFRMGEV NPELVRRHES KFIASRSYFD RVVNRSRPYM


 


101
YHIANEVKKR NMPAEAALLP FIESAFVTKA KSHVGASGLW QFMPATGRHY


 


151
GLEKTPVYDG RHDVYAATDA ALNYLQYLYG LFGDWPLAFA AYNWGEGNVG


 


201
RAVNRARDQG LEPTYENLRM PNETRNYVPK LLAVRNIIAT PQSFGMNISD


 


251
IDNKPYFQAV EPGRPLDNEA IARLAGITQS ELLALNPAFN VPAFIPKNKR


 


301
KLLLPVASVQ TFQSNYLNAA PDSLFSWEVY TPAAKTSLSD ISTATGMSIA


 


351
DIKRLNNLNG NLVNAGRSIL VAKNGKTLHT ASESVVSIDI DNTPDTYRSN


 


401
MPAGTVNVSI ARIQPAAAQT ADITVAPLPQ ETVRTGTRSP CPHYRTRPCD


 


451
SRSATSNRKT DCHAV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2101>:










m650.seq




1
ATGTCCAAAC TCAAAACCAT CGCTCTGACC GCATCAGGTC TGTCCGTTTG



 


51
TCCGGGTTTC CTATACGCCC AAAACACCTC ATCACACCAA ATCGGTTTGG


 


101
CGATTATGCG CTTAAACTCT TCAATACTCG ACCTGCCCCC GACAAAACAA


 


151
TATTTCCAAT CCGGCAGCCT GTGGGGCGAG CTGCGCCAAG GCTTCCGGAT


 


201
GGGCGAAGTC AATCCCGAAC TGGTACGCCG CCACGAAAGC AAATTCATCG


 


251
CAAGCCACAG CTATTTCAAC AGGGTCATCA ACCGGAGTAG ACCCTATATG


 


301
TACCATATCG CCAACGAAGT CAAAAAACGC AATATGCCCG CCGAAGCCGC


 


351
CCTGCTTCCC TTCATCGAAA GCGCGTTCGT CACCAAAGCC AAATCACACG


 


401
TCGGCGCATC AGGATTATGG CAGTTTATGC CCGCTACCGG CAGGCATTAC


 


451
GGCCTGGAAA AAACACCGGT TTACGACGGC AGGCACGACG TTTACGCCGC


 


501
CACCGATGCC GCACTCAACT ATCTGCAATA CCTCTATGGA CTGTTCGGCG


 


551
ACTGGCCGCT TGCCTTTGCC GCCTACAACT GGGGTGAAGG CAACGTCGGA


 


601
CGCGCCATCA ACCGCGCCCG CGCCCAAGGG CTCGAACCGA CCTACGAAAA


 


651
CCTGCGTATG CCCAACGAAA CGCGCAACTA TGTCCCCAAG CTGCTCGCCG


 


701
TGCGCAACAT TATTGCCACT CCCCAATCTT TCGGCATGAA TATCAGCGAC


 


751
ATAGACAACA AACCCTATTT TCAGGCAGTC GAACCGGATC GTCCGCTCGA


 


801
CAACGAAGCC ATCGCCCGGC TTGCCGGCAT CACGCAAAGC GAGCTGCTCG


 


851
CCCTAAACCC CGCATTCAAC GTCCCCGCGT TTATCCCCAA AAGCAAACGC


 


901
AAACTGCTGC TTCCTGTCGC GTCCGTACAA ACCTTCCAAA GCAACTACCT


 


951
CAACGCCGCA CCCGACAGCC TGTTTTCATG GGAAGTCTAT ACGCCTGCCG


 


1001
CCAAAACCAG CCTGTCCGAC ATCTCGACGG CAACCGGCAT GAGCATTGCC


 


1051
GACATCAAAC GCCTCAACAA CCTGAACGGC AACCTTGTCA ACGCAGGACG


 


1101
CAGCATCCTT GTCGCCAAGA ACGGCAAAAC CCTTCAGACG GCATCGGAAT


 


1151
CCGTCGTTTC CATCGACATC GACAATACGC CCGACACCTA CCGTTCCAAT


 


1201
ATGCCGGCAG GCACGGTGAA CGTCGGCATT GCCCGAATCC GACCCGCCGC


 


1251
CGCACAGACA GCGGACATTA CCGTCGCACC TTTGCCGCAG AAAACCGTCC


 


1301
GTACGG.AAC CCGATCCCCT TGTCCGTATT GCCGAACCTG CCCTTGCGAC


 


1351
AGCCGCAGCG CAACCTCAAA CCGAAAAACA GACCGCCATG CCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 2102; ORF 650>:










m650.pep




1
MSKLKTIALT ASGLSVCPGF LYAQNTSSHQ IGLAIMRLNS SILDLPPTKQ



 


51
YFQSGSLWGE LRQGFRMGEV NPELVRRHES KFIASHSYFN RVINRSRPYM


 


101
YHIANEVKKR NMPAEAALLP FIESAFVTKA KSHVGASGLW QFMPATGRHY


 


151
GLEKTPVYDG RHDVYAATDA ALNYLQYLYG LFGDWPLAFA AYNWGEGNVG


 


201
RAINRARAQG LEPTYENLRM PNETRNYVPK LLAVRNIIAT PQSFGMNISD


 


251
IDNKPYFQAV EPDRPLDNEA IARLAGITQS ELLALNPAFN VPAFIPKSKR


 


301
KLLLPVASVQ TFQSNYLNAA PDSLFSWEVY TPAAKTSLSD ISTATGMSIA


 


351
DIKRLNNLNG NLVNAGRSIL VAKNGKTLQT ASESVVSIDI DNTPDTYRSN


 


401
MPAGTVNVGI ARIRPAAAQT ADITVAPLPQ KTVRTXTRSP CPYCRTCPCD


 


451
SRSATSNRKT DRHAV*






m650/g650 96.1% identity in 465 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2103>:










a650.seq




1
ATGTCCAAAC TCAAAACCAT CGCCCTGACC GCGTCAGGTC TGTCCGTTTG



 


51
TCCGGGTTTC CTATACGCCC AAAACACCTC ATCACACCAA ATCGGTTTGG


 


101
CGATTATGCG CTTAAACTCT TCAATACTCG ACCTGCCACC GACAAAACAA


 


151
TATTTCCAAT CCGGCAGCCT GTGGAGCGAG CTGCGCCAAG GCTTCCGGAT


 


201
GGGCGAAGTC AATCCCGAAC TGGTACGCCG CCACGAAAGC AAATTCATCG


 


251
CAAGCCACAG CTATTTCAAC AGGGTCATCA ACCGGAGTAG ACCCTATATG


 


301
TACCATATCG CCAACGAAGT CAAAAAACGC AATATGCCCG CCGAAGCCGC


 


351
CCTGCTTCCC TTCATCGAAA GCGCGTTCGT CACCAAAGCC AAATCACACG


 


401
TCGGCGCATC GGGCCTGTGG CAGTTCATGC CCGCTACCGG CAGGCATTAC


 


451
GGCCTGGAAA AAACACCGGT TTACGACGGC AGGCACGACA TTTACGCCGC


 


501
CACCGATGCC GCACTCAACT ATCTGCAATA CCTCTATGGA CTGTTCGGCG


 


551
ACTGGCCGCT CGCCTTTGCC GCCTACAACT GGGGTGAAGG CAACGTCGGA


 


601
CGCGCCATCA ACCGCGCCCG CGCCCAAGGG CTCGAACCGA CCTACGAAAA


 


651
CCTGCGTATG CCCAACGAAA CGCGCAACTA TGTTCCCAAG CTGCTCGCCG


 


701
TGCGCAACAT CATTGCCGCC CCCCAATCTT TCGGCATGAA TATCAGCGAC


 


751
ATAGACAACA AACCGTATTT TCAGGCAGTC GAACCGGACC GTCCGCTCGA


 


801
CAACGAAGCC ATCGCCCGGC TTGCCGGCAT CACGCAAAGC GAGCTGCTCG


 


851
CCCTAAACCC CGCATTCAAC GTCCCCGCGT TCATCCCCAA AAGCAAACGC


 


901
AAACTGCTGC TTCCTGTCGC GTCCGTACAA ACCTTCCAAA GCAACTACCT


 


951
CAACGCCGCA CCCGACAGCC TGTTTTCATG GGAAGTCTAT ACGCCTGCCG


 


1001
CCAAAACCAG CTTGTCCGAC ATCTCGACGG CAACCGGCAT GAGCATTGCC


 


1051
GACATCAAAC GCCTCAACAA CCTGAACGGC AACCTTGTCA ACGCAGGACG


 


1101
CAGCATCCTT GTCGCCAAGA ACGGCAAAAC CCTTCAGACG GCATCGGAAT


 


1151
CCGTCGTTTC CATCGACATC GACAATACGC CCAACACCTA CCGTTCCAAT


 


1201
ATGCCGGCAG GCACGGTGAA CGTCGGCATT GCCCGAATCC GACCCGCCGC


 


1251
CGCACAGACA GCGGACATTA CCGTCGCACC TTTGCCGCAG AAAACCGTCC


 


1301
GTACGG.AAC CCGATCCCCT TGTCCGTATT GCCGAACCTG CCCTTGCGAC


 


1351
AGCCGCAGCG CAACCTCAAA CCGAAAAACA GACCGCCATG CCGTCTGA






This corresponds to the amino acid sequence <SEQ ID 2104; ORF 650.a>:










a650.pep




1
MSKLKTIALT ASGLSVCPGF LYAQNTSSHQ IGLAIMRLNS SILDLPPTKQ



 


51
YFQSGSLWSE LRQGFRMGEV NPELVRRHES KFIASHSYFN RVINRSRPYM


 


101
YHIANEVKKR NMPAEAALLP FIESAFVTKA KSHVGASGLW QFMPATGRHY


 


151
GLEKTPVYDG RHDIYAATDA ALNYLQYLYG LFGDWPLAFA AYNWGEGNVG


 


201
RAINRARAQG LEPTYENLRM PNETRNYVPK LLAVRNIIAA PQSFGMNISD


 


251
IDNKPYFQAV EPDRPLDNEA IARLAGITQS ELLALNPAFN VPAFIPKSKR


 


301
KLLLPVASVQ TFQSNYLNAA PDSLFSWEVY TPAAKTSLSD ISTATGMSIA


 


351
DIKRLNNLNG NLVNAGRSIL VAKNGKTLQT ASESVVSIDI DNTPNTYRSN


 


401
MPAGTVNVGI ARIRPAAAQT ADITVAPLPQ KTVRTXTRSP CPYCRTCPCD


 


451
SRSATSNRKT DRHAV*






m650/a650 99.1% identity in 465 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2105>:










g652.seq




1
ATGATCGAAT TGGACGGTAC TGAAAACAAA GGCAATTTGG GTGCGAATGC


 


51
GACTTTGGCG GTCTCTATGG CGGTTGCACG CGCCGCTGCC GAAGACTCAG


 


101
GCCTGCCGCT TTACCGCTAC TTGGGGGGCG CAGGTCCGAT GTCCCTGCCC


 


151
GTACCGATGA TGAACGTCAT CAACGGCGGC GAACACGCCA ACAACAGCCT


 


201
GAACATCCAA GAGTTTATGA TTATGCCCGT CGGCGCAAAA TCTTTCCGCG


 


251
AAGCGTTGCG CTGCGGTGCG GAAATTTTCC ACGCCTTGAA AAAACTGTGC


 


301
GACAGTAAAG GCTTCCCGAC CACAGTCGGC GACGAAGGCG GTTTCGCCCC


 


351
CAACCTGAAC AGCCACAAAG AAGCCCTGCA ACTGATGGTC GAAGCGGCCG


 


401
AAGCCGCCGG CTACAAGGCG GGCGAAGACG TATTATTCGC ATTGGACTGC


 


451
GCGTCCAGCG AGTTCTACAA AGACGGCAAA TACCACTTGG AAGCCGAAGG


 


501
CCGCTCCTAC ACCAACGCGG AATTTGCCGA ATACTTGGAA GGCTTGGTTA


 


551
ACGAATTCCC GATTATTTCC ATTGAAGACG GGATGGACGA AAACGACTGG


 


601
GAAGGCTGGA AACTGCTGAC CGAAAAATTG GGCAAAAAAG TTCAATTGGT


 


651
CGGCGACGAC TTGTTCGTAA CCAATCCGAA AATTCTTGCC GAAGGCATCG


 


701
AAAAAGGCGT AGCAAACGCA TTGCTGGTCA AAGTCAACCA AATCGGTACT


 


751
TTAAGCGAAA CCCTGAAAGc cgtcgatctg gCAAAATGCA accgctacGc


 


801
cagCGTGATG AGCCAccgct ccggCGAAAC CGAAGACAGT Accattgccg


 


851
ACTTGGCAGT CGCCACCAAC TGTATGCAGA TTAAAAccgG TTCTTTGAGc


 


901
cgTTCCGACC GCATGGCGAA ATACAACCAa ctGCTGCGTA TCGAGGAAGA


 


951
ATTGGCGGAA GCcgcctACT ACCCCGGCAA AGCCGCATTC TACCAACTGG


 


1001
GCAAATAA






This corresponds to the amino acid sequence <SEQ ID 2106; ORF 652.ng>:










g652.pep




1
MIELDGTENK GNLGANATLA VSMAVARAAA EDSGLPLYRY LGGAGPMSLP



 


51
VPMMNVINGG EHANNSLNIQ EFMIMPVGAK SFREALRCGA EIFHALKKLC


 


101
DSKGFPTTVG DEGGFAPNLN SHKEALQLMV EAAEAAGYKA GEDVLFALDC


 


151
ASSEFYKDGK YHLEAEGRSY TNAEFAEYLE GLVNEFPIIS IEDGMDENDW


 


201
EGWKLLTEKL GKKVQLVGDD LFVTNPKILA EGIEKGVANA LLVKVNQIGT


 


251
LSETLKAVDL AKCNRYASVM SHRSGETEDS TIADLAVATN CMQIKTGSLS


 


301
RSDRMAKYNQ LLRIEEELAE AAYYPGKAAF YQLGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2107>:










m652.seq




1
ATGATCGAAT TGGACGGTAC TGAAAACAAA GGCAATTTGG GTGCGAATGC



 


51
GACTTTGGCG GTTTCTATGG CGGTTGCACG CGCCGCTGCC GAAGACTCAG


 


101
GCCTGCCGCT TTACCGCTAC TTGGGCGGCG CAGGCCCGAT GTCCCTGCCC


 


151
GTACCGATGA TGAACGTCAT CAACGGCGGC GAACACGCCA ACAACAGCCT


 


201
GAACATCCAA GAGTTTATGA TTATGCCCGT CGGCGCAAAA TCTTTCCGCG


 


251
AAGCGTTGCG CTGCGGTGCG GAAATTTTCC ACGCCTTGAA AAAACTGTGC


 


301
GACAGCAAAG GCTTCCCGAC CACAGTCGGC GACGAAGGCG GTTTCGCCCC


 


351
CAACCTGAAC AGCCACAAAG AAGCCCTGCA ACTGATGGTC GAGGCGACCG


 


401
AAGCCGCCGG CTACAAAGCG GGCGAAGACG TATTATTCGC ATTGGACTGC


 


451
GCCTCCAGCG AGTTCTACAA AGACGGCAAA TACCACTTGG AAGCCGAAGG


 


501
CCGCTCCTAC ACCAACGCGG AATTTGCCGA ATATCTGGAA GGCCTGGTCA


 


551
ACGAGTTCCC CATCATCTCC ATCGAAGACG GCATGGATGA AAACGACTGG


 


601
GAAGGCTGGA AACTGCTGAC CGAAAAACTG GGCGGTAGAG TTCAATTGGT


 


651
TGGCGACGAC TTGTTCGTAA CCAATCCAAA AATCTTGGCC GAAGGCATCG


 


701
AAAAAGGCGT AGCAAACGCA TTGCTGGTCA AAGTCAATCA AATCGGTACT


 


751
TTGAGCGAGA CCCTGAAAGC CGTCGACTTA GCCAAACGCA ACCGCTACGC


 


801
CAGCGTAATG AGCCACCGCT CCGGCGAAAC CGAAGACAGC ACCATTGCCG


 


851
ACTTGGCAGT CGCCACCAAC TGTATGCAGA TCAAAACCGG TTCTTTGAGC


 


901
CGTTCCGACC GCATGGCGAA ATACAACCAA CTGCTGCGTA TCGAGGAAGA


 


951
ATTGGCGGAA GCCGCCGACT ACCCCAGCAA AGCCGCATTC TACCAACTGG


 


1001
GCAAATAA






This corresponds to the amino acid sequence <SEQ ID 2108; ORF 652>:










m652.pep




1
MIELDGTENK GNLGANATLA VSMAVARAAA EDSGLPLYRY LGGAGPMSLP


 


51
VPMMNVINGG EHANNSLNIQ EFMIMPVGAK SFREALRCGA EIFHALKKLC


 


101
DSKGFPTTVG DEGGFAPNLN SHKEALQLMV EATEAAGYKA GEDVLFALDC


 


151
ASSEFYKDGK YHLEAEGRSY TNAEFAEYLE GLVNEFPIIS IEDGMDENDW


 


201
EGWKLLTEKL GGRVQLVGDD LFVTNPKILA EGIEKGVANA LLVKVNQIGT


 


251
LSETLKAVDL AKRNRYASVM SHRSGETEDS TIADLAVATN CMQIKTGSLS


 


301
RSDRMAKYNQ LLRIEEELAE AADYPSKAAF YQLGK






m652/g652 98.2% identity in 335 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2109>:










a652.seq




1
ATGATCGAAT TGGACGGTAC TGAAAACAAA GGCAATTTGG GTGCGAATGC


 


51
GACTTTGGCG GTTTCTATGG CGGTTGCACG CGCCGCTGCC GAAGACTCAG


 


101
GCCTGCCGCT TTACCGCTAC TTGGGCGGCG CAGGCCCGAT GTCCCTGCCC


 


151
GTACCGATGA TGAACGTCAT CAACGGCGGC GAACACGCCA ACAACAGCCT


 


201
GAACATCCAA GAGTTTATGA TTATGCCCGT CGGCGCAAAA TCTTTCCGCG


 


251
AAGCGTTGCG CTGCGGTGCG GAAATTTTCC ACGCCTTGAA AAAACTGTGC


 


301
GACAGCAAAG GCTTCCCGAC CACAGTCGGC GACGAAGGCG GTTTCGCCCC


 


351
CAACCTGAAC AGCCACAAAG AAGCCCTGCA ACTGATGGTC GAGGCGACCG


 


401
AAGCCGCCGG CTACAAAGCG GGCGAAGACG TATTATTCGC ATTGGACTGC


 


451
GCGTCCAGCG AGTTCTACAA AGACGGCAAA TACCACTTGG AAGCCGAAGG


 


501
CCGCTCCTAC ACCAACGCGG AATTTGCCGA ATATCTGGAA GGCCTGGTCA


 


551
ACGAGTTCCC CATCATCTCC ATCGAAGACG GGATGGATGA AAACGACTGG


 


601
GAAGGCTGGA AACTGCTGAC CGAAAAACTG GGCGGCAAAG TCCAACTCGT


 


651
TGGCGACGAC CTCTTCGTTA CCAACCCGAA AATCCTTGCC GAAGGCATTG


 


701
AAAAAGGCGT GGCAAACGCA CTATTGGTCA AAGTCAACCA AATCGGTACT


 


751
TTGAGTGAAA CCCTGAAAGC CGTCGACTTA GCCAAACGCA ACCGCTACGC


 


801
CAGCGTAATG AGCCACCGCT CCGGCGAAAC CGAAGACAGC ACCATTGCCG


 


851
ACTTGGCAGT CGCCACCAAC TGTATGCAGA TCAAAACCGG TTCTTTGAGC


 


901
CGTTCCGACC GCATGGCGAA ATACAACCAA CTGCTGCGTA TCGAGGAAGA


 


951
ATTGGCGGAA GCCGCCGACT ACCCCAGCAA AGCCGCATTC TACCAACTGG


 


1001
GCAAATAA






This corresponds to the amino acid sequence <SEQ ID 2110; ORF 652.a>:










a652.pep




1
MIELDGTENK GNLGANATLA VSMAVARAAA EDSGLPLYRY LGGAGPMSLP


 


51
VPMMNVINGG EHANNSLNIQ EFMIMPVGAK SFREALRCGA EIFHALKKLC


 


101
DSKGFPTTVG DEGGFAPNLN SHKEALQLMV EATEAAGYKA GEDVLFALDC


 


151
ASSEFYKDGK YHLEAEGRSY TNAEFAEYLE GLVNEFPIIS IEDGMDENDW


 


201
EGWKLLTEKL GGKVQLVGDD LFVTNPKILA EGIEKGVANA LLVKVNQIGT


 


251
LSETLKAVDL AKRNRYASVM SHRSGETEDS TIADLAVATN CMQIKTGSLS


 


301
RSDRMAKYNQ LLRIEEELAE AADYPSKAAF YQLGK*






m652/a652 99.7% identity in 335 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2111>:










g652-1.seq




1
ATGAGCGCAA TCGTTGATAT TTTCGCCCGC GAAATTTTGG ACTCACGCGG


 


51
CAACCCCACA GTCGAGTGTG ATGTATTGCT CGAATCCGGC GTAATGGGAC


 


101
GTGCGGCCGT ACCGAGCGGC GCATCCACCG GTCAGAAAGA AGCTTTGGAA


 


151
CTTCGCGACG GCGACAAATC CCGCTATTCC GGCAAAGGCG TATTGAAGGC


 


201
CGTCGAACAC GTCAACAACC AAATCGCCCA AGCCCTCATC GGTATCGATG


 


251
CCAACGAGCA ATCTTATATC GACCAAATCA TGATCGAATT GGACGGTACT


 


301
GAAAACAAAG GCAATTTGGG TGCGAATGCG ACTTTGGCGG TCTCTATGGC


 


351
GGTTGCACGC GCCGCTGCCG AAGACTCAGG CCTGCCGCTT TACCGCTACT


 


401
TGGGGGGCGC AGGTCCGATG TCCCTGCCCG TACCGATGAT GAACGTCATC


 


451
AACGGCGGCG AACACGCCAA CAACAGCCTG AACATCCAAG AGTTTATGAT


 


501
TATGCCCGTC GGCGCAAAAT CTTTCCGCGA AGCGTTGCGC TGCGGTGCGG


 


551
AAATTTTCCA CGCCTTGAAA AAACTGTGCG ACAGTAAAGG CTTCCCGACC


 


601
ACAGTCGGCG ACGAAGGCGG TTTCGCCCCC AACCTGAACA GCCACAAAGA


 


651
AGCCCTGCAA CTGATGGTCG AAGCGGCCGA AGCCGCCGGC TACAAGGCGG


 


701
GCGAAGACGT ATTATTCGCA TTGGACTGCG CGTCCAGCGA GTTCTACAAA


 


751
GACGGCAAAT ACCACTTGGA AGCCGAAGGC CGCTCCTACA CCAACGCGGA


 


801
ATTTGCCGAA TACTTGGAAG GCTTGGTTAA CGAATTCCCG ATTATTTCCA


 


851
TTGAAGACGG GATGGACGAA AACGACTGGG AAGGCTGGAA ACTGCTGACC


 


901
GAAAAATTGG GCAAAAAAGT TCAATTGGTC GGCGACGACT TGTTCGTAAC


 


951
CAATCCGAAA ATTCTTGCCG AAGGCATCGA AAAAGGCGTA GCAAACGCAT


 


1001
TGCTGGTCAA AGTCAACCAA ATCGGTACTT TAAGCGAAAC CCTGAAAGCC


 


1051
GTCGATCTGG CAAAATGCAA CCGCTACGCC AGCGTGATGA GCCACCGCTC


 


1101
CGGCGAAACC GAAGACAGTA CCATTGCCGA CTTGGCAGTC GCCACCAACT


 


1151
GTATGCAGAT TAAAACCGGT TCTTTGAGCC GTTCCGACCG CATGGCGAAA


 


1201
TACAACCAAC TGCTGCGTAT CGAGGAAGAA TTGGCGGAAG CCGCCTACTA


 


1251
CCCCGGCAAA GCCGCATTCT ACCAACTGGG CAAATAA






This corresponds to the amino acid sequence <SEQ ID 2112; ORF 652-1.ng>:










g652-1.pep




1
MSAIVDIFAR EILDSRGNPT VECDVLLESG VMGRAAVPSG ASTGQKEALE


 


51
LRDGDKSRYS GKGVLKAVEH VNNQIAQALI GIDANEQSYI DQIMIELDGT


 


101
ENKGNLGANA TLAVSMAVAR AAAEDSGLPL YRYLGGAGPM SLPVPMMNVI


 


151
NGGEHANNSL NIQEFMIMPV GAKSFREALR CGAEIFHALK KLCDSKGFPT


 


201
TVGDEGGFAP NLNSHKEALQ LMVEAAEAAG YKAGEDVLFA LDCASSEFYK


 


251
DGKYHLEAEG RSYTNAEFAE YLEGLVNEFP IISIEDGMDE NDWEGWKLLT


 


301
EKLGKKVQLV GDDLFVTNPK ILAEGIEKGV ANALLVKVNQ IGTLSETLKA


 


351
VDLAKCNRYA SVMSHRSGET EDSTIADLAV ATNCMQIKTG SLSRSDRMAK


 


401
YNQLLRIEEE LAEAAYYPGK AAFYQLGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2113>:










m652-1.seq




1
ATGAGCGCAA TCGTTGATAT TTTCGCCCGC GAAATTTTGG ACTCACGCGG


 


51
CAACCCCACA GTCGAGTGTG ATGTATTGCT CGAATCCGGC GTAATGGGAC


 


101
GCGCAGCCGT ACCGAGCGGC GCGTCCACCG GTCAAAAAGA GGCTTTGGAA


 


151
CTTCGCGACG GCGACAAATC CCGTTATTCG GGCAAGGGCG TATTGAAGGC


 


201
GGTCGAACAC GTCAACAACC AAATCGCCCA AGCCCTCATT GGTATCGATG


 


251
CCAACGAGCA ATCTTATATC GACCAAATCA TGATCGAATT GGACGGTACT


 


301
GAAAACAAAG GCAATTTGGG TGCGAATGCG ACTTTGGCGG TTTCTATGGC


 


351
GGTTGCACGC GCCGCTGCCG AAGACTCAGG CCTGCCGCTT TACCGCTACT


 


401
TGGGCGGCGC AGGCCCGATG TCCCTGCCCG TACCGATGAT GAACGTCATC


 


451
AACGGCGGCG AACACGCCAA CAACAGCCTG AACATCCAAG AGTTTATGAT


 


501
TATGCCCGTC GGCGCAAAAT CTTTCCGCGA AGCGTTGCGC TGCGGTGCGG


 


551
AAATTTTCCA CGCCTTGAAA AAACTGTGCG ACAGCAAAGG CTTCCCGACC


 


601
ACAGTCGGCG ACGAAGGCGG TTTCGCCCCC AACCTGAACA GCCACAAAGA


 


651
AGCCCTGCAA CTGATGGTCG AGGCGACCGA AGCCGCCGGC TACAAAGCGG


 


701
GCGAAGACGT ATTATTCGCA TTGGACTGCG CCTCCAGCGA GTTCTACAAA


 


751
GACGGCAAAT ACCACTTGGA AGCCGAAGGC CGCTCCTACA CCAACGCGGA


 


801
ATTTGCCGAA TATCTGGAAG GCCTGGTCAA CGAGTTCCCC ATCATCTCCA


 


851
TCGAAGACGG CATGGATGAA AACGACTGGG AAGGCTGGAA ACTGCTGACC


 


901
GAAAAACTGG GCGGTAGAGT TCAATTGGTT GGCGACGACT TGTTCGTAAC


 


951
CAATCCAAAA ATCTTGGCCG AAGGCATCGA AAAAGGCGTA GCAAACGCAT


 


1001
TGCTGGTCAA AGTCAATCAA ATCGGTACTT TGAGCGAGAC CCTGAAAGCC


 


1051
GTCGACTTAG CCAAACGCAA CCGCTACGCC AGCGTAATGA GCCACCGCTC


 


1101
CGGCGAAACC GAAGACAGCA CCATTGCCGA CTTGGCAGTC GCCACCAACT


 


1151
GTATGCAGAT CAAAACCGGT TCTTTGAGCC GTTCCGACCG CATGGCGAAA


 


1201
TACAACCAAC TGCTGCGTAT CGAGGAAGAA TTGGCGGAAG CCGCCGACTA


 


1251
CCCCAGCAAA GCCGCATTCT ACCAACTGGG CAAATAA






This corresponds to the amino acid sequence <SEQ ID 2114; ORF 652-1>:










m652-1.pep




1
MSAIVDIFAR EILDSRGNPT VECDVLLESG VMGRAAVPSG ASTGQKEALE


 


51
LRDGDKSRYS GKGVLKAVEH VNNQIAQALI GIDANEQSYI DQIMIELDGT


 


101
ENKGNLGANA TLAVSMAVAR AAAEDSGLPL YRYLGGAGPM SLPVPMMNVI


 


151
NGGEHANNSL NIQEFMIMPV GAKSFREALR CGAEIFHALK KLCDSKGFPT


 


201
TVGDEGGFAP NLNSHKEALQ LMVEATEAAG YKAGEDVLFA LDCASSEFYK


 


251
DGKYHLEAEG RSYTNAEFAE YLEGLVNEFP IISIEDGMDE NDWEGWKLLT


 


301
EKLGGRVQLV GDDLFVTNPK ILAEGIEKGV ANALLVKVNQ IGTLSETLKA


 


351
VDLAKRNRYA SVMSHRSGET EDSTIADLAV ATNCMQIKTG SLSRSDRMAK


 


401
YNQLLRIEEE LAEAADYPSK AAFYQLGK*






m652-1/g652-1 98.6% identity in 428 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2115>:










a652-1.seq




1
ATGAGCGCAA TCGTTGATAT TTTCGCCCGC GAAATTTTGG ACTCACGCGG


 


51
CAACCCCACA GTCGAGTGTG ATGTATTGCT CGAATCCGGC GTAATGGGAC


 


101
GCGCAGCCGT ACCGAGCGGC GCGTCCACCG GTCAAAAAGA GGCTTTGGAA


 


151
CTTCGCGACG GCGACAAATC CCGTTATTCG GGCAAGGGCG TATTGAAGGC


 


201
GGTCGAACAC GTCAACAACC AAATCGCCCA AGCCCTCATT GGTATCGATG


 


251
CCAACGAGCA ATCTTATATC GACCAAATCA TGATCGAATT GGACGGTACT


 


301
GAAAACAAAG GCAATTTGGG TGCGAATGCG ACTTTGGCGG TTTCTATGGC


 


351
GGTTGCACGC GCCGCTGCCG AAGACTCAGG CCTGCCGCTT TACCGCTACT


 


401
TGGGCGGCGC AGGCCCGATG TCCCTGCCCG TACCGATGAT GAACGTCATC


 


451
AACGGCGGCG AACACGCCAA CAACAGCCTG AACATCCAAG AGTTTATGAT


 


501
TATGCCCGTC GGCGCAAAAT CTTTCCGCGA AGCGTTGCGC TGCGGTGCGG


 


551
AAATTTTCCA CGCCTTGAAA AAACTGTGCG ACAGCAAAGG CTTCCCGACC


 


601
ACAGTCGGCG ACGAAGGCGG TTTCGCCCCC AACCTGAACA GCCACAAAGA


 


651
AGCCCTGCAA CTGATGGTCG AGGCGACCGA AGCCGCCGGC TACAAAGCGG


 


701
GCGAAGACGT ATTATTCGCA TTGGACTGCG CGTCCAGCGA GTTCTACAAA


 


751
GACGGCAAAT ACCACTTGGA AGCCGAAGGC CGCTCCTACA CCAACGCGGA


 


801
ATTTGCCGAA TATCTGGAAG GCCTGGTCAA CGAGTTCCCC ATCATCTCCA


 


851
TCGAAGACGG GATGGATGAA AACGACTGGG AAGGCTGGAA ACTGCTGACC


 


901
GAAAAACTGG GCGGCAAAGT CCAACTCGTT GGCGACGACC TCTTCGTTAC


 


951
CAACCCGAAA ATCCTTGCCG AAGGCATTGA AAAAGGCGTG GCAAACGCAC


 


1001
TATTGGTCAA AGTCAACCAA ATCGGTACTT TGAGTGAAAC CCTGAAAGCC


 


1051
GTCGACTTAG CCAAACGCAA CCGCTACGCC AGCGTAATGA GCCACCGCTC


 


1101
CGGCGAAACC GAAGACAGCA CCATTGCCGA CTTGGCAGTC GCCACCAACT


 


1151
GTATGCAGAT CAAAACCGGT TCTTTGAGCC GTTCCGACCG CATGGCGAAA


 


1201
TACAACCAAC TGCTGCGTAT CGAGGAAGAA TTGGCGGAAG CCGCCGACTA


 


1251
CCCCAGCAAA GCCGCATTCT ACCAACTGGG CAAATAA






This corresponds to the amino acid sequence <SEQ ID 2116; ORF 652-1.a>:










a652-1.pep




1
MSAIVDIFAR EILDSRGNPT VECDVLLESG VMGRAAVPSG ASTGQKEALE


 


51
LRDGDKSRYS GKGVLKAVEH VNNQIAQALI GIDANEQSYI DQIMIELDGT


 


101
ENKGNLGANA TLAVSMAVAR AAAEDSGLPL YRYLGGAGPM SLPVPMMNVI


 


151
NGGEHANNSL NIQEFMIMPV GAKSFREALR CGAEIFHALK KLCDSKGFPT


 


201
TVGDEGGFAP NLNSHKEALQ LMVEATEAAG YKAGEDVLFA LDCASSEFYK


 


251
DGKYHLEAEG RSYTNAEFAE YLEGLVNEFP IISIEDGMDE NDWEGWKLLT


 


301
EKLGGKVQLV GDDLFVTNPK ILAEGIEKGV ANALLVKVNQ IGTLSETLKA


 


351
VDLAKRNRYA SVMSHRSGET EDSTIADLAV ATNCMQIKTG SLSRSDRMAK


 


401
YNQLLRIEEE LAEAADYPSK AAFYQLGK*






m652-1/a652-1 99.8% identity in 428 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2117>:










g653.seq




1
ATGGCGGcgg aaccgatgcg gAtgccggag gtaAcgtaCG GTTTTTCCGG


 


51
ATCGTTCGGG ATGGCGTTTT TGTtgacggT GATGTGCGCt ttgcccaAAG


 


101
CGGCTtcggc ggctttgcCg gtgaTTTTCA TCGGTTGCAG GtcgacgaGG


 


151
AAaacgTGGC TTTCGGTGCG GCCGGAAacg atgcgCaaac cgCGTttaac


 


201
caactcttcc gcCATGACGG CAGCATTGAT TTTCACTTGT TTTGCGTATT


 


251
GTTTGAactC GGGTTGcaac gcttctTTAA acgctACGGC TttgGCGGCG


 


301
ATAACGTgca tcaACGGAcc gCCTTGCAGG CTTGGGAAGA TGGAAGAGTT


 


351
CAGCGCTTTT TCGTGGGTAT TGTCACGGCA CAAAATCACA CCGCCGCGAG


 


401
GGCCGCGTAG GGTTTTGTGG GTGGTAGTGg ttACgaaGTc GCAGAatggc


 


451
ACGGGgttag gatattcgcc gccGGCAACC AgtccgGCAT Ag






This corresponds to the amino acid sequence <SEQ ID 2118; ORF 653.ng>:










g653.pep




1
MAAEPMRMPE VTYGFSGSFG MAFLLTVMCA LPKAASAALP VIFIGCRSTR


 


51
KTWLSVRPET MRKPRLTNSS AMTAALIFTC FAYCLNSGCN ASLNATALAA


 


101
ITCINGPPCR LGKMEEFSAF SWVLSRHKIT PPRGPRRVLW VVVVTKSQNG


 


151
TGLGYSPPAT SPA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2119>:










m653.seq




1
ATGGCAGCGG AGCCGATGCG GATGCCGGAG GTAACGAAGG GTTTTTCCGG


 


51
ATCGTTCGGA ATGGCGTTTT TGTTGACGGT GATGTGCGCT TTGCCCAAAG


 


101
CGGCTTCGGC GGCTTTGCCG GTAATTTTCA TCGGTTGCAG GTCAACGAGG


 


151
AAAACGTGGC TTTCGGTGCG GCCGGAAACG ATGCGCAAAC CGCGTTTAAC


 


201
CAACTCTTCC GCCATGGCGG CTGCATTGAT TTTCACTTGT TTTGCGTATT


 


251
GTTTGAACTC GGGTTGCAAT GCTTCTTTAA ACGCCACGGC TTTGGCGGCG


 


301
ATAACGTGCA TCAGCGGACC GCCTTGCAGG CTTGGGAAGA TGGAAGAGTT


 


351
CAACGCTTTT TCGTGGGTAT TGTCGCGGCA CAAAATTACG CCGCCGCGAG


 


401
GACCGCGCAG GGTTTTGTGG GTGGTGGTGG TCACGAAGTC GCAGAACGGC


 


451
ACCGGGTTGG GATATTCGCC GCCGGCAACC AGACCGGCAT AG






This corresponds to the amino acid sequence <SEQ ID 2120; ORF 653>:










m653.pep




1
MAAEPMRMPE VTKGFSGSFG MAFLLTVMCA LPKAASAALP VIFIGCRSTR


 


51
KTWLSVRPET MRKPRLTNSS AMAAALIFTC FAYCLNSGCN ASLNATALAA


 


101
ITCISGPPCR LGKMEEFNAF SWVLSRHKIT PPRGPRRVLW VVVVTKSQNG


 


151
TGLGYSPPAT RPA*






m653/g653 96.9% identity in 163 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2121>:










a653.seq




1
ATGGCGGCGG AACCGATGCG GATGCCGGAG GTAACGAAGG GTTTTTCCGG


 


51
ATCATTCGGG ATGGCGTTTT TGTTGACAGT GATGTGCGCT TTGCCCAAAG


 


101
CAGCTTCGGC GGCTTTGCCG GTAATTTTCA TCGGTTGCAG GTCAACGAGG


 


151
AAAACGTGGC TTTCGGTGCG GCCGGAAACG ATGCGCAAAC CGCGTTTAAC


 


201
CAACTCTTCC GCCATGGCGG CTGCATTGAT TTTCACTTGT TTTGCGTATT


 


251
GTTTGAACTC GGGTTGCAAT GCTTCTTTAA ACGCCACGGC TTTGGCGGCG


 


301
ATAACGTGCA TCAGCGGGCC ACCTTGCAGG CTTGGGAAGA TGGAAGAGTT


 


351
CAACGCTTTT TCGTGGGTAT TGTCGCGGCA CAAAATTACG CCGCCGCGAG


 


401
GACCGCGCAG GGTTTTGTGG GTGGTGGTGG TAACGAAGTC GCAGAACGGC


 


451
ACGGGATTGG GATATTCGCC GCCGGCAACC AGACCGGCAT AG






This corresponds to the amino acid sequence <SEQ ID 2122; ORF 653.a>:










a653.pep




1
MAAEPMRMPE VTKGFSGSFG MAFLLTVMCA LPKAASAALP VIFIGCRSTR


 


51
KTWLSVRPET MRKPRLTNSS AMAAALIFTC FAYCLNSGCN ASLNATALAA


 


101
ITCISGPPCR LGKMEEFNAF SWVLSRHKIT PPRGPRRVLW VVVVTKSQNG


 


151
TGLGYSPPAT RPA*






m653/a653 100.0% identity in 163 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2123>:










g656.seq




1
ATGCCGCGTT TCTCCGGTTC GATTTCTTCG ATGATTTCCA TCGCGCGGAC


 


51
TTTtggcGCG CCGGAGAGTG TGCcggcagg gAAGGTGGCG GCGAGGATGT


 


101
CCATATTGGT AACGCCCTCT TTCAAACAGc ctTCGACGTT GGAAACGATG


 


151
TGCATCACAT GGGAGTATTT TTCAATCACC ATTTTGTCGG TGACTTTGAC


 


201
TTCGCCTGTT TTGCTGATGC GTCCGACATC GTTGCGCCCC AAATCGATAA


 


251
GCATAACGTG TTCGGCgatt TCTTTGGCGT CGCTTAACAA ATCTTGTTCG


 


301
TTGGCAAGGT CTTCGGCGGG GGTTTTGCCG CGCAGGCGCG TGCCGGCGAT


 


351
GGGGCGGACG ATGACGTcat CGCGTTCGCG GCGGACGAGG ATTTCGGGCG


 


401
AGGAACCGAC GATGTGGAAA TCGCCGAAAT CGTAG






This corresponds to the amino acid sequence <SEQ ID 2124; ORF 656.ng>:










g656.pep




1
MPRFSGSISS MISIARTFGA PESVPAGKVA ARMSILVTPS FKQPSTLETM


 


51
CITWEYFSIT ILSVTLTSPV LLMRPTSLRP KSISITCSAI SLASLNKSCS


 


101
LARSSAGVLP RRRVPAMGRT MTSSRSRRTR ISGEEPTMWK SPKS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2125>:










m656.seq




1
ATGCCGCGTT TGCTCGGTTC GACTTCTTCG ATGATTTCCA TGGCGCGGAC


 


51
TTTGGGTGCG CCGGAGAGTG TGCCGGCAGG GAAGGTAGCG GCGAGGATGT


 


101
CCATGTTGGT CATGCCGTCT TTCAGACGGC CTTCGACGTT GGAAACGATG


 


151
TGCATTACAT GGGAGTATTT TTCAATCACC ATTTTGTCGG TAACTTTGAC


 


201
TTCGCCGGTT TTACTGATGC GGCCGACGTC GTTGCGTCCT AAGTCAATCA


 


251
ACATGACGTG TTCGGCGATT TCTTTGGCAT CGCTTAACAA ATCTTGTTCG


 


301
TTGGCAAGGT CTTCGGCGGG GGTTTTGCCG CGCAGGCGCG TGCCGGCGAT


 


351
GGGGCGGACG ATAACGTCGT TGCGTTCGCG TCGGACGAGG ATTTCGGGCG


 


401
AGGAGCCGAC GATGTGGAAA TCGCCGAAAT CGTAG






This corresponds to the amino acid sequence <SEQ ID 2126; ORF 656>:










m656.pep




1
MPRLLGSTSS MISMARTLGA PESVPAGKVA ARMSMLVMPS FRRPSTLETM


 


51
CITWEYFSIT ILSVTLTSPV LLMRPTSLRP KSINMTCSAI SLASLNKSCS


 


101
LARSSAGVLP RRRVPAMGRT ITSLRSRRTR ISGEEPTMWK SPKS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m656/g656 91.0% identity in 144 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2127>:










a656.seq




1
ATGCCGCGTT TGCTCGGTTC GACTTCTTCG ATGATTTCCA TGGCGCGGAC


 


51
TTTGGGTGCG CCGGAGAGTG TGCCGGCAGG GAAGGTAGCG GCGAGGATGT


 


101
CCATGTTGGT CATGCCGTCT TTCAGACGGC CTTCGACGTT GGAAACGATG


 


151
TGCATTACAT GGGAGTATTT TTCAATCACC ATTTTGTCGG TAACTTTGAC


 


201
TTCGCCGGTT TTACTGATGC GGCCGACGTC GTTGCGTCCT AAGTCAATCA


 


251
ACATGACGTG TTCGGCGATT TCTTTGGCAT CGCTTAACAA ATCTTGTTCG


 


301
TTGGCAAGGT CTTCGGCGGG GGTTTTGCCG CGCAGGCGCG TGCCGGCGAT


 


351
GGGGCGGACG ATGACATCGT CGCGTTCGCG GCGGACGAGG ATTTCGGGCG


 


401
AGGAGCCGAC GATGTGGAAA TCGCCGAAAT CGTAG






This corresponds to the amino acid sequence <SEQ ID 2128; ORF 656.a>:










a656.pep




1
MPRLLGSTSS MISMARTLGA PESVPAGKVA ARMSMLVMPS FRRPSTLETM


 


51
CITWEYFSIT ILSVTLTSPV LLMRPTSLRP KSINMTCSAI SLASLNKSCS


 


101
LARSSAGVLP RRRVPAMGRT MTSSRSRRTR ISGEEPTMWK SPKS*






m656/a656 98.6% identity in 144 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2129>:










g657.seq




1
ATGAACACAC CCCCCATCCT TCCTCCCGCC ATGCTCGGCA TCCTCGGCGG


 


51
CGGACAATTa ggcagAATGT TTGCCGTTGC CGCTAAAACC ATGGGCTACA


 


101
AAGTAACCGT TCTCGATCCC GACCCGAATG CGCCGGCGGC GGAATTTGCC


 


151
GACCGCCATT TGTGCGCGCC GTTTGACGAC CGGGCCGCGT TGGACGAATT


 


201
GGCAAAATGC GCGGCGGTta cgACCGAATT TGAAAacgtc aaTGCCGACG


 


251
CGATGCGCTC TCTGGCAAAG CATACCAACG TTTCCCCCAG CGGCGACTGC


 


301
GTGTCCATTG CACAAAACCG CATTCAGGAA AAAGCGTGGA TACGCAAAGC


 


351
AGGCTTGCAA ACCGCGCCGT ATCAGGCGGT TTGCAAGGCC GAAGACATTA


 


401
CTGAAGCAAG CGCGCAATTT TTGCCCGGCA TCCTGAAAAC GGCTACGTTG


 


451
GGCTACGACG GCAAAGGTCA AATCCGCGTC AAAACGTTGG ACGAACTCAA


 


501
AGCCGCGTTT GCCGAACACG GCGGCGTGGA TTGCGTTTTG GAAAAAATGG


 


551
TGGACTTGCG CGGCGAGATT TCCGTGATCG TATGCCGTCT GAACGATGAA


 


601
AACGTGCAAA CCTTCGACCC CGCCGAAAAC ATCCACGAAA ACGGCATCTT


 


651
GGCTTattcC ATCGTCcccg CGCGGCTGAG TGCCGACGTG CAGCAACAGG


 


701
CGCGGCAGAC GGCGCAACgc tTGGCGGACG AATTGGATTA TGTCGGCgta


 


751
TTGGCGGTAG AAATGTTTGT TGTCGGCGAC ACACATGAAT TGCTCGTCAA


 


801
TGAAACCGCC CCGCGCACGC ACAATTCCGG CCACCATACG ATAGATGCCT


 


851
GCGCCGCAGA CCAGTTCCAA CAGCAGGTAC GCATTATGTG CAAcctGCCG


 


901
cccGccgACA CCAAATTATT aTCCCCttgC TGTATGGCGA ATATTTTGGg


 


951
CGACGTTTGG CAGGAAGATG GCGGCGAACC GGATTGGCTG CCGTTGCAAA


 


1001
GCCGGCCGAA TGCACACCTG CACCTATACG GAAAAAAAAC CGCACAGAAA


 


1051
GGTCGGAAAA TGGGACACTT TaccgTTTTG ACCACCGATT CGGACaccgC


 


1101
ATTTCAAGAA GCAAAAAAAC TGCATCAGTC CCTATAA






This corresponds to the amino acid sequence <SEQ ID 2130; ORF 657.ng>:










g657.pep




1
MNTPPILPPA MLGILGGGQL GRMFAVAAKT MGYKVTVLDP DPNAPAAEFA


 


51
DRHLCAPFDD RAALDELAKC AAVTTEFENV NADAMRSLAK HTNVSPSGDC


 


101
VSIAQNRIQE KAWIRKAGLQ TAPYQAVCKA EDITEASAQF LPGILKTATL


 


151
GYDGKGQIRV KTLDELKAAF AEHGGVDCVL EKMVDLRGEI SVIVCRLNDE


 


201
NVQTFDPAEN IHENGILAYS IVPARLSADV QQQARQTAQR LADELDYVGV


 


251
LAVEMFVVGD THELLVNETA PRTHNSGHHT IDACAADQFQ QQVRIMCNLP


 


301
PADTKLLSPC CMANILGDVW QEDGGEPDWL PLQSRPNAHL HLYGKKTAQK


 


351
GRKMGHFTVL TTDSDTAFQE AKKLHQSL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2131>:










m657.seq




1
ATGAAAAACA TATCTCTTTC TCCGCCCGCC ATGCTTGGCA TCCTCGGCGG


 


51
CGGACAATTA GGCAGAATGT TTACCGTTGC CGCCAAAACC ATGGGCTACA


 


101
AAGTAACCGT TCTCGACCCC GATCCGGACG CGCCGGCAGC AGAATTTGCC


 


151
GACCGCCATT TGTGCGCGCC GTTTAACGAC CAAGCTGCTT TGGACGAATT


 


201
GGCAAAATGC GCGGCGGTGA CCACTGAATT TGAAAACGTC AATGCCGATG


 


251
CGATGCGCTT TTTGGCAAAA CATACCAATG TTTCCCCTAG CGGCGATTGT


 


301
GTGGCGATTG CACAAAACCG CATTCAGGAA AAGGCATGGA TACGCAAAGC


 


351
GGGATTGCAA ACCGCGCCGT ATCAAGTGGT TTGTAAGGCT GAAGACATCA


 


401
CTGAAGCAAG CGCGCAATTT TTGCCCGGCA TCCTGAAAAC GGCTACGTTG


 


451
GGCTACGACG GCAAAGGTCA AATCCGCGTA AAAACATTGG ATGAACTCAA


 


501
AGCCGCGTTT GCCGAACACG GCGGCGTGGA TTGCGTTTTG GAAAAAATGG


 


551
TGGATTTGCG CAGTGAAATT TCCGTAATCG TATGCCGTTT GAACAATGAC


 


601
AACGTGCAAA CTTTCGACCC TGCCGAAAAC ATCCACGAAA ACGGCATCTT


 


651
GGCTTATTCC ATCGTCCCCG CGCGACTGAG TGCCGACGTG CAGCAACAGG


 


701
CGCGGCAGAT GGCGCAACGC TTGGCGGACG AATTGGATTA TGTCGGCGTA


 


751
TTGGCGGTAG AAATGTTTGT TGTCGGTGAC ACGCATGAAT TGGTCGTCAA


 


801
CGAAATCGCC CCGCGCCCGC ACAATTCCGG ACACCATACG ATAGATGCCT


 


851
GCGCAGCAGA CCAGTTCCAG CAGCAGGTAC GCATTATGTG CAACCTGCCG


 


901
CCTGCCGATA CCAAATTACT GAGTTCTTGC TGTATGGCAA ATATTTTGGG


 


951
CGACGTTTGG CAGGAAGACG GCGGCGAACC GGATTGGCTG CCCTTGCAAA


 


1001
GCCATCCGAA TGCACACCTG CACCTTTACG GCAAAAAAAC CGCGCACAAA


 


1051
GGGCGGAAAA TGGGACACTT TACCGTTTTA ACCACCGATT CGGACACCGC


 


1101
ATTTCAAGAA GCAAAAAAAC TGCATCAGTC CCTATAA






This corresponds to the amino acid sequence <SEQ ID 2132; ORF 657>:










m657.pep




1
MKNISLSPPA MLGILGGGQL GRMFTVAAKT MGYKVTVLDP DPDAPAAEFA


 


51
DRHLCAPFND QAALDELAKC AAVTTEFENV NADAMRFLAK HTNVSPSGDC


 


101
VAIAQNRIQE KAWIRKAGLQ TAPYQVVCKA EDITEASAQF LPGILKTATL


 


151
GYDGKGQIRV KTLDELKAAF AEHGGVDCVL EKMVDLRSEI SVIVCRLNND


 


201
NVQTFDPAEN IHENGILAYS IVPARLSADV QQQARQMAQR LADELDYVGV


 


251
LAVEMFVVGD THELVVNEIA PRPHNSGHHT IDACAADQFQ QQVRIMCNLP


 


301
PADTKLLSSC CMANILGDVW QEDGGEPDWL PLQSHPNAHL HLYGKKTAHK


 


351
GRKMGHFTVL TTDSDTAFQE AKKLHQSL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m657/g657 93.9% identity in 378 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2133>:










a657.seq




1
ATGAAAAACA TATCTCTTTC TCCGCCCGCC ATGCTCGGCA TTCTTGGCGG


 


51
CGGACAATTA GGCAGAATGT TTACTGTTGC TGCCAAAACC ATGGGCTACA


 


101
AAGTAACCGT ACTCGATCCC AACCCGAATG CGCCGGCAGC GGAATTTGCC


 


151
GACCGCCATT TGTGTGCGCC GTTTGACAAC CAAACCGCTT TGGAAGAATT


 


201
GGCAAAATGT GCGGCTGTTA CGACCGAGTT CGAAAACGTC AATGCCGATG


 


251
CGATGCGTTT TCTCGCCAAA CATACCAATG TTTCCCCCAG CGGCGACTGC


 


301
GTTGCCATCG CGCAAAACCG CATTCAGGAA AAGGCATGGA TACGCAAAGC


 


351
AGGCCTGCAA ACCGCGCCGT ATCAAGCAAT TTGCAAAGCC GAAGACATCA


 


401
CTGAAGAAAG CATACAATTT CTGCCCGGCA TCCTGAAAAC CGCTACATTG


 


451
GGCTATGACG GCAAAGGCCA AATCCGCGTC AAAACGGTGG ATGAACTCAA


 


501
AGCCGCGTTT GCCGAACACC GCGGCGTGGA TTGCGTTTTG GAAAAAATGG


 


551
TGGACTTGCG CGGCGAAATT TCCGTTATCG TATGCCGTCT GAACAATGAC


 


601
AACGTGCAAA CTTTCGATCC TGCCGAAAAC ATTCACGAAA ACGGTATCCT


 


651
CGCCTACTCC ATCGTCCCAG CCCGACTGAG TGCCGACATT CAGCAACAGG


 


701
CGCGACAAAT GGCGCAGCGT TTGGCCGATG AATTGAACTA CGTCGGCGTA


 


751
TTGGCGGTAG AAATGTTTGT TGTCGGCGAC ACGCATGAAT TGGTCGTCAA


 


801
CGAAATCGCG CCGCGTCCGC ACAATTCCGG CCACCATACC GTCGACGCCT


 


851
GCGCGGCAGA CCAATTCCAG CAACAGGTCC GCCTGATGTG CAACCTGCCA


 


901
CCTGCTGACA CCAAATTGCT GAGTTCTTGC TGTATGGCGA ATATTTTGGG


 


951
CGACGTTTGG CAGGAAGACG GCGGCGAACC GGATTGGTTT CCCCTGCAAA


 


1001
GCCGGCCGGA CGCGCACCTG CACCTTTACG GCAAAAAAAC CGCGCACAAA


 


1051
GGGCGGAAAA TGGGACACTT TACCATTTTA AGCACCGATT CGGACACCGC


 


1101
ATTTCAAGAA GCAAAAAAAC TGCATCAGTC CCTATAA






This corresponds to the amino acid sequence <SEQ ID 2134; ORF 657.a>:










a657.pep




1
MKNISLSPPA MLGILGGGQL GRMFTVAAKT MGYKVTVLDP NPNAPAAEFA


 


51
DRHLCAPFDN QTALEELAKC AAVTTEFENV NADAMRFLAK HTNVSPSGDC


 


101
VAIAQNRIQE KAWIRKAGLQ TAPYQAICKA EDITEESIQF LPGILKTATL


 


151
GYDGKGQIRV KTVDELKAAF AEHRGVDCVL EKMVDLRGEI SVIVCRLNND


 


201
NVQTFDPAEN IHENGILAYS IVPARLSADI QQQARQMAQR LADELNYVGV


 


251
LAVEMFVVGD THELVVNEIA PRPHNSGHHT VDACAADQFQ QQVRLMCNLP


 


301
PADTKLLSSC CMANILGDVW QEDGGEPDWF PLQSRPDAHL HLYGKKTAHK


 


351
GRKMGHFTIL STDSDTAFQE AKKLHQSL*






m657/a657 94.2% identity in 378 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2135>:










g658.seq




1
ATGGTGGCCG GAATTGTGCG TGCGCGGGGC GGTTTCATTG ACGAGCAATT


 


51
CATGTGTGTC GCCGACAACA AACATTTCTA CCGCCAAtac GCCGACATAA


 


101
TCCAATTCGT CCGCCAagcG TTGCGCCGTC TGCCGCGCCT GTTGCTGCAC


 


151
GTCGGCACTC AGCCGCGcgg gGACGATGga atAAGCCAAG ATGCCGTTTT


 


201
CGTGGATGTT TTCGGCGGGG TCGAAGGTTT GCACGTTTTC ATCGTTCAGA


 


251
CGGCATACGA TCACGGAAAT CTCGCCGCGC AAGTCCACCA TTTTTTCCAA


 


301
AACGCAATCC ACGCCGCCGT GTTCGGCAAA CGCGGCTTTG AGTTCGTCCA


 


351
ACGTTTTGAC GCGGATTTGA CCTTTGCCGT CGTAGCCCAA CGTAGCCGTT


 


401
TTCAGGATGC CGGGCAAAAA TTGCGCGCTT GCTTCAGTAA TGTCTTCGGC


 


451
CTTGCAAACC GCCTGATACG GCGCGGTTTG CAAGCCTGCT TTGCGTATCC


 


501
ACGCTTTTTC CTGAATGCGG TTTTGTGCAA TGGACACGCA GTCGCCGCTG


 


551
GGGGAAACGT TGGTATGCTT TGCCAGAGAG CGCATCGCGT CGGCAttgac


 


601
gtTTTCAAAT TCGGTcgtaA CCGCCGCGCA TTTTGCCAAT TCGTCCAACG


 


651
CGGCCCGGTC GTCAAACGGC GCGCACAAAT GGCGGTCGGC AAATTCCGCC


 


701
GCCGGCGCAT TCGGGTCGGG ATCGAGAACG GTTACTTTGT AGCCCATGGT


 


751
TTTAGCGGCA ACGGCAAACA TTctgcctAA






This corresponds to the amino acid sequence <SEQ ID 2136; ORF 658.ng>:










g658.pep




1
MVAGIVRARG GFIDEQFMCV ADNKHFYRQY ADIIQFVRQA LRRLPRLLLH


 


51
VGTQPRGDDG ISQDAVFVDV FGGVEGLHVF IVQTAYDHGN LAAQVHHFFQ


 


101
NAIHAAVFGK RGFEFVQRFD ADLTFAVVAQ RSRFQDAGQK LRACFSNVFG


 


151
LANRLIRRGL QACFAYPRFF LNAVLCNGHA VAAGGNVGML CQRAHRVGID


 


201
VFKFGRNRRA FCQFVQRGPV VKRRAQMAVG KFRRRRIRVG IENGYFVAHG


 


251
FSGNGKHSA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2137>:










m658.seq




1
ATGGTGTCCG GAATTGTGCG GGCGCGGGGC GATTTCGTTG ACGACCAATT


 


51
CATGCGTGTC ACCGACAACA AACATTTCTA CCGCCAATAC GCCGACATAA


 


101
TCCAATTCGT CCGCCAAGCG TTGCGCCATC TGCCGCGCCT GTTGCTGCAC


 


151
GTCGGCACTC AGTCGCGCGG GGACGATGGA ATAAGCCAAG ATGCCGTTTT


 


201
CGTGGATGTT TTCGGCAGGG TCGAAAGTTT GCACGTTGTC ATTGTTCAAA


 


251
CGGCATACGA TTACGGAAAT TTCACTGCGC AAATCCACCA TTTTTTCCAA


 


301
AACGCAATCC ACGCCGCCGT GTTCGGCAAA CGCGGCTTTG AGTTCATCCA


 


351
ATGTTTTTAC GCGGATTTGA CCTTTGCCGT CGTAGCCCAA CGTAGCCGTT


 


401
TTCAGGATGC CGGGCAAAAA TTGCGCGCTT GCTTCAGTGA TGTCTTCAGC


 


451
CTTACAAACC ACTTGATACG GCGCGGTTTG CAATCCCGCT TTGCGTATCC


 


501
ATGCCTTTTC CTGAATGCGG TTTTGTGCAA TCGCCACACA ATCGCCGCTA


 


551
GGGGAAACAT TGGTATGTTT TGCCAAAAAG CGCATCGCAT CGGCATTGAC


 


601
GTTTTCAAAT TCAGTGGTCA CCGCCGCGCA TTTTGCCAAT TCGTCCAAAG


 


651
CAGCTTGGTC GTTAAACGGC GCGCACAAAT GGCGGTCGGC AAATTCTGCT


 


701
GCCGGCGCGT CCGGATCGGG GTCGAGAACG GTTACTTTGT AGCCCATGGT


 


751
TTTGGCGGCA ACGGTAAACA TTCTGCCTAA






This corresponds to the amino acid sequence <SEQ ID 2138; ORF 658>:










m658.pep




1
MVSGIVRARG DFVDDQFMRV TDNKHFYRQY ADIIQFVRQA LRHLPRLLLH


 


51
VGTQSRGDDG ISQDAVFVDV FGRVESLHVV IVQTAYDYGN FTAQIHHFFQ


 


101
NAIHAAVFGK RGFEFIQCFY ADLTFAVVAQ RSRFQDAGQK LRACFSDVFS


 


151
LTNHLIRRGL QSRFAYPCLF LNAVLCNRHT IAARGNIGMF CQKAHRIGID


 


201
VFKFSGHRRA FCQFVQSSLV VKRRAQMAVG KFCCRRVRIG VENGYFVAHG


 


251
FGGNGKHSA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m658/g658 82.2% identity in 259 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2139>:










a658.seq




1
ATGGTGGCCG GAATTGTGCG GACGCGGCGC GATTTCGTTG ACGACCAATT


 


51
CATGCGTGTC GCCGACAACA AACATTTCTA CCGCCAATAC GCCGACGTAG


 


101
TTCAATTCAT CGGCCAAACG CTGCGCCATT TGTCGCGCCT GTTGCTGAAT


 


151
GTCGGCACTC AGTCGGGCTG GGACGATGGA GTAGGCGAGG ATACCGTTTT


 


201
CGTGAATGTT TTCGGCAGGA TCGAAAGTTT GCACGTTGTC ATTGTTCAGA


 


251
CGGCATACGA TAACGGAAAT TTCGCCGCGC AAGTCCACCA TTTTTTCCAA


 


301
AACGCAATCC ACGCCGCGGT GTTCGGCAAA CGCGGCTTTG AGTTCATCCA


 


351
CCGTTTTGAC GCGGATTTGG CCTTTGCCGT CATAGCCCAA TGTAGCGGTT


 


401
TTCAGGATGC CGGGCAGAAA TTGTATGCTT TCTTCAGTGA TGTCTTCGGC


 


451
TTTGCAAATT GCTTGATACG GCGCGGTTTG CAGGCCTGCT TTGCGTATCC


 


501
ATGCCTTTTC CTGAATGCGG TTTTGCGCGA TGGCAACGCA GTCGCCGCTG


 


551
GGGGAAACAT TGGTATGTTT GGCGAGAAAA CGCATCGCAT CGGCATTGAC


 


601
GTTTTCGAAC TCGGTCGTAA CAGCCGCACA TTTTGCCAAT TCTTCCAAAG


 


651
CGGTTTGGTT GTCAAACGGC GCACACAAAT GGCGGTCGGC AAATTCCGCT


 


701
GCCGGCGCAT TCGGGTTGGG ATCGAGTACG GTTACTTTGT AGCCCATGGT


 


751
TTTGGCAGCA ACAGTAAACA TTCTGCCTAA






This corresponds to the amino acid sequence <SEQ ID 2140; ORF 658.a>:










a658.pep




1
MVAGIVRTRR DFVDDQFMRV ADNKHFYRQY ADVVQFIGQT LRHLSRLLLN


 


51
VGTQSGWDDG VGEDTVFVNV FGRIESLHVV IVQTAYDNGN FAAQVHHFFQ


 


101
NAIHAAVFGK RGFEFIHRFD ADLAFAVIAQ CSGFQDAGQK LYAFFSDVFG


 


151
FANCLIRRGL QACFAYPCLF LNAVLRDGNA VAAGGNIGMF GEKTHRIGID


 


201
VFELGRNSRT FCQFFQSGLV VKRRTQMAVG KFRCRRIRVG IEYGYFVAHG


 


251
FGSNSKHSA*






m658/a658 75.3% identity in 259 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2141>:










g661.seq




1
ATGCACATCG GCGGTTATTT TATCGACAAC CCCATCGCAC TTGCGCCGAT


 


51
GGCGGGCATT GCCGACAAAC CCTTCCGCCG CCTCTGTCGG GCGTTTGGCG


 


101
CAGGTTGGGC GGTGTGCGAA ATGCTGGCCA GCGATCCGAC GCTCAGGAAT


 


151
ACCGGAAAAA CCCtgcaccg cagtgaTTTt gccgatgaag gCGGCATCGT


 


201
TGCCGTGCAG ATTGCCGGCA GCGACCccga acaGATGGCG Gatgcggcgc


 


251
gttacAACGT CGGACTCGGG GCGCAGGTCA TCGACATcaa TATGGGCTGC


 


301
cccgccaaGA AAGTGTGCAA CGTCCAAGCC GGTAGCGCgc tGATGCAGGA


 


351
CGAGccgctg gttgcCgcca tTTtggaggc ggtggtcAAG GCGGCGGgcg


 


401
TACCCGTTAC cctCAAAACc cgtTtgggtt ggcacgacga cgatcaaaac


 


451
ctgcCcgccg tcgccaaaat cgccgaagat tgcggcattg ccgccCttgc


 


501
cgttccacgg gcgCGCgcgC ACGCAAATGT ACAAAGGCGA GGCgcGTTAC


 


551
Gaactcatcg CCGAGACCAA AAGccgTCTG AACATCCCGG cctGggtCAA


 


601
CGGCGACATC actTCgccgc AAAAAGCCGC CGccgTCCTC AAACAAACCG


 


651
CCGCCGACGG CATCATGATA GGGCGCGGCG CGCAAGGCAG GCCGTGGTTT


 


701
TTCCGCGATT TGAAGCATTA TGCCGAACAC GGCGTTTTAC CGCCTGCCTT


 


751
GAGTTTGGCA GAATGCAGAG CCGCCATTTT GAACCACATC CGCGCCATGC


 


801
ACGCGTTTTA TGGTGAGACC GTCGGTGTGC GCATCGCACG CAAACACATA


 


851
GGCTGGTACA TCGGCGAAAT GCCCGACGGC GAACAGGCGC GGCGTGA






This corresponds to the amino acid sequence <SEQ ID 2142; ORF 661.ng>:










g661.pep




1
MHIGGYFIDN PIALAPMAGI ADKPFRRLCR AFGAGWAVCE MLASDPTLRN


 


51
TGKTLHRSDF ADEGGIVAVQ IAGSDPEQMA DAARYNVGLG AQVIDINMGC


 


101
PAKKVCNVQA GSALMQDEPL VAAILEAVVK AAGVPVTLKT RLGWHDDDQN


 


151
LPAVAKIAED CGIAALAVPR ARAHANVQRR GALRTHRRDQ KPSEHPGLGQ


 


201
RRHHFAAKSR RRPQTNRRRR HHDRARRARQ AVVFPRFEAL CRTRRFTACL


 


251
EFGRMQSRHF EPHPRHARVL WXDRRCAHRT QTHRLVHRRN ARRRTGAA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2143>:










m661.seq




1
ATGCACATCG GCGGCTATTT TATCGACAAC CCCATCGCAC TTGCGCCGAT


 


51
GGCGGGCATT ACCGACAAAC CGTTCCGCCG ACTTTGCCGA GATTTTGGCG


 


101
CAGGTTGGGC GGTGTGCGAA ATGCTGACCA GCGACCCGAC GCTCAGAAAT


 


151
ACTAGAAAAA CCTTGCACCG CAGCGATTTT GCCGATGAAG GCGGCATTGT


 


201
TGCCGTGCAG ATTGCCGGAA GCGATCCGCA GCAGATGGCG GATGCCGCGC


 


251
GTTACAACGT CAGCCTTGGG GCGCAGCTTA TCGACATCAA CATGGGCTGT


 


301
CCCGCTAAAA AAGTCTGCAA TGTCCAAGCC GGTAGCGCGC TGATGCAGAA


 


351
CGAGCCGCTG GTTGCCGCCA TTTTGGAAGC CGTCGTCCGT GCGGCAGGCG


 


401
TACCCGTTAC CCTCAAAACC CGTTTGGGTT GGCACGACGA CCATCAAAAC


 


451
CTGCCCGTCA TCGCCAAAAT CGCCGAAGAT TGCGGCATCG CCGCCCTTGC


 


501
CGTCC.ACGG ACGCACGCGT ACGCAAATGT ACAAAGGCGA AGCGCGTTAC


 


551
GAACTCATCG CCGAAACCAA ATGCCGTCTG AACATCCCGG TCTGGGTCAA


 


601
CGGCGACATT ACTTCGCCGC AAAAAGCCCA AGCCGTCCTC AAACAAACCG


 


651
CCGCCGACGG CATTATGATA GGGCGCGGCG CGCAAGGCAG GCCGTGGTTC


 


701
TTCCGCGATT TGAAACATTA TGCCGAACAC GGTGTTTTGC CGCCTGCCTT


 


751
GAGTTTGGCA GAATGCGCCG CCGCTATTTT GAACCACATC CGCGCCATAC


 


801
ACGCGTTTTA CGGCGACACC GCCGGTGTGC GCATCGCACG CAAACACATA


 


851
GGCTGGTACA TCGACGAAAT GCCCGACGGC GAACAGACAC GTCGTGA






This corresponds to the amino acid sequence <SEQ ID 2144; ORF 661>:










m661.pep




1
MHIGGYFIDN PIALAPMAGI TDKPFRRLCR DFGAGWAVCE MLTSDPTLRN


 


51
TRKTLHRSDF ADEGGIVAVQ IAGSDPQQMA DAARYNVSLG AQLIDINMGC


 


101
PAKKVCNVQA GSALMQNEPL VAAILEAVVR AAGVPVTLKT RLGWHDDHQN


 


151
LPVIAKIAED CGIAALAVXR THAYANVQRR SALRTHRRNQ MPSEHPGLGQ


 


201
RRHYFAAKSP SRPQTNRRRR HYDRARRARQ AVVLPRFETL CRTRCFAACL


 


251
EFGRMRRRYF EPHPRHTRVL RRHRRCAHRT QTHRLVHRRN ARRRTDTS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m661/g661 88.5% identity in 295 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2145>:










a661.seq




1
ATGCACATCG GCGGCTATTT TATCGACAAC CCCATCGCAC TTGCGCCGAT


 


51
GGCGGGCATT ACCGACAAAC CGTTCCGCCG ACTTTGCCGA GATTTTGGCG


 


101
CAGGTTGGGC GGTGTGCGAA ATGCTGACCA GCGACCCGAC GCTCAGAAAT


 


151
ACTAGAAAAA CCTTGCACCG CAGCGATTTT GCCGATGAAG GCGGCATTGT


 


201
TGCCGTGCAG ATTGCCGGAA GCGATCCGCA GCAGATGGCG GATGCCGCGC


 


251
GTTACAACGT CAGCCTTGGG GCGCAGCTTA TCGACATCAA CATGGGCTGT


 


301
CCCGCTAAAA AAGTCTGCAA TGTCCAAGCC GGTAGCGCGC TGATGCAGAA


 


351
CGAGCCGCTG GTTGCCGCCA TTTTGGAGGC GGTGGTCAAA GCGGCGGGCG


 


401
TACCCGTTAC CCTCAAAACC CGTTTGGGTT GGCACGACGA CCATCAAAAC


 


451
CTGCCCGTCA TCGCCAAAAT CGCCGAAGAT TGCGGCATTG CCGCCCTTGC


 


501
CG.TCCACGG ACGCACGCGC ACGCAAATGT ACAAAGGCGA AGCGGCTTAC


 


551
GACCTGATTG CCGAAACCAA ATGCCGTCTG AACATCCCGG TCTGGGTCAA


 


601
CGGCGACATT ACCTCGCCGC AAAAAGCCCA AGCCGTCCTC AAACAAACCG


 


651
CCGCAGACGG CATTATGATA GGGCGCGGCG CGCAAGGCAG ACCGTGGTTC


 


701
TTCCGCGATT TGAAACATTA CGCCGAACAC GGTGTTTTAC CGCCTGCCTT


 


751
GAGTTTGGCA GAATGTACCG CCACTATTTT GAACCACATC CGAGCCATGC


 


801
ACGCGTTTTA CGGCGACACC GCCGGTGTGC GCATCGCACG CAAACACATA


 


851
GGCTGGTACA TCGACGAAAT GCCCGACGGC GAACAGACAC GTCGTGA






This corresponds to the amino acid sequence <SEQ ID 2146; ORF 661.a>:










a661.pep




1
MHIGGYFIDN PIALAPMAGI TDKPFRRLCR DFGAGWAVCE MLTSDPTLRN


 


51
TRKTLHRSDF ADEGGIVAVQ IAGSDPQQMA DAARYNVSLG AQLIDINMGC


 


101
PAKKVCNVQA GSALMQNEPL VAAILEAVVK AAGVPVTLKT RLGWHDDHQN


 


151
LPVIAKIAED CGIAALAXPR THAHANVQRR SGLRPDCRNQ MPSEHPGLGQ


 


201
RRHYLAAKSP SRPQTNRRRR HYDRARRARQ TVVLPRFETL RRTRCFTACL


 


251
EFGRMYRHYF EPHPSHARVL RRHRRCAHRT QTHRLVHRRN ARRRTDTS*






m661/a661 94.6% identity in 298 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2147>:










g663.seq




1
ATGTGTACCG AGATGAAATT TATATTTTTT GTACTGTATG TTTTGCAGTT


 


51
TCTGCCGTTT GCGCTGCTGC ACAAGATTGC CGGCCTGATC GGTTCGCTTG


 


101
CCTACCTTCT GGTCAAACCG CGCCGCCGTA TCGGCGAAAT CAATTTGGCA


 


151
AAATGTTTTC CCGAATGGGA CGAAGAAAAG CGTAAAACCG TGTTGAAACA


 


201
GCATTTCAAA CACATGGCAA AACTGATGCT CGAATACGGC TTATATTGGT


 


251
ACGCGtctGC CAAATGCCTG AAATCGCTGG TGCGCTACCG CAATAAGCAT


 


301
TATTTGGACG ACGCGCTGGC GGCGGGGGAA AAAGTCATCA TCCTGTACCC


 


351
GCACTTTACC GCGTTCGAGA TGGCGGTGTA CGCGCTTAAT CAGGATGTCC


 


401
CGCTGATCAG TATGTATTCC CACCAAAAAA ACAAGATATT GGACGAACAG


 


451
ATTTTGAAAg gccgcaACCG CTATCACAAC GTCTTCCTTA TCGGGCGCAC


 


501
CGAagggctg cgCGCCCtcg TCAAACAGTT CCGCAAAAGC AGTGCGCCGT


 


551
TCCTGTATCT GCCCGATCAG GATTTCGGAC GCAACAATTC GGTTTTTGTG


 


601
GATTTTTTCG GCATtcagaC GGCAACGATT ACCGGCTTGA GCCGCATTGC


 


651
CGCGCTTGCA AATGCAAAAG TGATACCCGC CATTCCCGTC CGCGAGGCGG


 


701
ACAATACGGT TACATTGCAA TTCTATCCCG CTTGGAAATC CTTTCCGAGT


 


751
GAAGACGCGC AAGCCGACGC GCAACGTATG AACCGCTTTA TCGAAGAACG


 


801
CGTGCGCGAA CACCCGGAAC AATATTTCTG GCTGCACAAG CGTTTCAAAA


 


851
CCCGTCCGGA AGGCAGCCCC GATTTTTACT GA






This corresponds to the amino acid sequence <SEQ ID 2148; ORF 663.ng>:










g663.pep




1
MCTEMKFIFF VLYVLQFLPF ALLHKIAGLI GSLAYLLVKP RRRIGEINLA


 


51
KCFPEWDEEK RKTVLKQHFK HMAKLMLEYG LYWYASAKCL KSLVRYRNKH


 


101
YLDDALAAGE KVIILYPHFT AFEMAVYALN QDVPLISMYS HQKNKILDEQ


 


151
ILKGRNRYHN VFLIGRTEGL RALVKQFRKS SAPFLYLPDQ DFGRNNSVFV


 


201
DFFGIQTATI TGLSRIAALA NAKVIPAIPV READNTVTLQ FYPAWKSFPS


 


251
EDAQADAQRM NRFIEERVRE HPEQYFWLHK RFKTRPEGSP DFY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2149>:










m663.seq




1
ATGTGTATCG AGATGAAATT TATATTTTTT GTACTGTATG TTTTGCAGTT


 


51
TCTGCCGTTT GCGCTGCTGC ACAAGATTGC CGACCTGACG GGTTTGCTTG


 


101
CCTACCTTCT GGTCAAACCG CGCCGCCGTA TCGGCGAAAT CAATTTGGCA


 


151
AAATGTTTTT CCGAATGGAG TGAGGAAAAG CGTAAAACCG TGTTGAAACA


 


201
GCATTTCAAA CACATGGCGA AACTGATGTT GGAATACGGT TTATATTGGT


 


251
ACGCGCCTGC CGGACGTTTG AAATCGCTGG TGCGCTACCG CAATAAGCAT


 


301
TATTTGGACG ACGCGCTGGC GGCGGGGGAA AAAGTCATCA TCCTGTATCC


 


351
GCACTTCACC GCGTTCGAGA TGGCGGTGTA CGCGCTTAAT CAGGATATCC


 


401
CGCTGATCAG TATGTATTCC CATCAAAAAA ACAAGATATT GGACGAACAG


 


451
ATTTTGAAAG GCCGCAACCG CTATCACAAC GTCTTCCTTA TCGGGCGCAC


 


501
CGAAGGGCTG CGCGCCCTCG TCAAACAGTT CCGCAAAAGC AGCGCGCCGT


 


551
TTCTGTATCT GCCCGATCAG GATTTCGGAC GCAACGATTC GGTTTTTGTG


 


601
GATTTTTTCG GTATTCAGAC GGCAACGATT ACCGGATTGA GCCGCATTGC


 


651
CGCGCTTGCA AATGCAAAAG TGATACCCGC CATTCCCGTC CGCGAGGCAG


 


701
ACAATACGGT TACATTGCAT TTCTACCCTG CTTGGAAATC CTTTCCGGGT


 


751
GAAGACGCGA AAGCCGACGC GCAGCGCATG AACCGTTTTA TCGAAGACAG


 


801
GGTGCGCGAA CATCCGGAAC AATATTTTTG GCTGCACAAG CGTTTTAAAA


 


851
CCCGTCCGGA AGGCAGCCCC GATTTTTACT GA






This corresponds to the amino acid sequence <SEQ ID 2150; ORF 663>:










m663.pep




1
MCIEMKFIFF VLYVLQFLPF ALLHKIADLT GLLAYLLVKP RRRIGEINLA


 


51
KCFSEWSEEK RKTVLKQHFK HMAKLMLEYG LYWYAPAGRL KSLVRYRNKH


 


101
YLDDALAAGE KVIILYPHFT AFEMAVYALN QDIPLISMYS HQKNKILDEQ


 


151
ILKGRNRYHN VFLIGRTEGL RALVKQFRKS SAPFLYLPDQ DFGRNDSVFV


 


201
DFFGIQTATI TGLSRIAALA NAKVIPAIPV READNTVTLH FYPAWKSFPG


 


251
EDAKADAQRM NRFIEDRVRE HPEQYFWLHK RFKTRPEGSP DFY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m663/g663 94.9% identity in 293 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2151>:










a663.seq




1
ATGTGTATCG AGATGAAATT TATATTTTTT GTACTGTATG TTTTGCAGTT


 


51
TCTGCCGTTT GCGCTGCTGC ACAAACTTGC TGATCTGACA GGCTTGCTCG


 


101
CCTACCTTTT GGTCAAACCC CGCCGCCGTA TCGGCGAAAT CAATTTGGCA


 


151
AAATGCTTTC CCGAGTGGGA CGGAAAAAAG CGTAAAACCG TGTTGAAACA


 


201
GCATTTCAAA CATATGGCGA AACTGATGTT GGAATACGGT TTATATTGGT


 


251
ACGCGCCCGC CGGGCGTTTG AAATCACTGG TGCGCTACCG CAACAAACAT


 


301
TATTTGGACG ACGCTCTGGC GGCAGGGGAA AAAGTCATCA TCCTGTATCC


 


351
GCACTTCACC GCGTTCGAGA TGGCGGTGTA CGCGCTCAAT CAGGATGTTC


 


401
CGCTGATCAG TATGTATTCC CACCAAAAAA ACAAGATATT GGACGAACAG


 


451
ATTTTGAAAG GCCGCAACCG CTATCACAAC GTTTTCCTTA TCGGGCGCAC


 


501
CGAAGGGCTG CGCGCCCTCG TCAAACAGTT CCGCAAAAGC AGCGCGCCGT


 


551
TTCTGTATCT GCCCGATCAG GATTTCGGAC GCAACGATTC GGTTTTTGTC


 


601
GATTTCTTCG GTATTCGGAC GGCAACGATT ACCGGCTTGA GCCGCATTGC


 


651
CGCGCTTGCA AATGCAAAAG TGATACCCGC CATCCCTGTC CGCGAGGCGG


 


701
ACAATACGGT TACATTGCAT TTCTACCCTG CTTGGGAATC CTTTCCGAGT


 


751
GAAGATGCGC AGGCCGACGC GCAGCGCATG AACCGTTTTA TCGAGGAACG


 


801
CGTGCGCGAA CATCCCGAGC AGTATTTTTG GCTGCACAAG CGTTTCAAAA


 


851
CCCGTCCGGA AGGCAGCCCC GATTTTTACT GA






This corresponds to the amino acid sequence <SEQ ID 2152; ORF 663.a>:










a663.pep




1
MCIEMKFIFF VLYVLQFLPF ALLHKLADLT GLLAYLLVKP RRRIGEINLA


 


51
KCFPEWDGKK RKTVLKQHFK HMAKLMLEYG LYWYAPAGRL KSLVRYRNKH


 


101
YLDDALAAGE KVIILYPHFT AFEMAVYALN QDVPLISMYS HQKNKILDEQ


 


151
ILKGRNRYHN VFLIGRTEGL RALVKQFRKS SAPFLYLPDQ DFGRNDSVFV


 


201
DFFGIRTATI TGLSRIAALA NAKVIPAIPV READNTVTLH FYPAWESFPS


 


251
EDAQADAQRM NRFIEERVRE HPEQYFWLHK RFKTRPEGSP DFY*






m663/a663 96.2% identity in 293 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2153>:










g664.seq




1
ATGATACATC CGCACCACTT CCGCGCCTTT TTCATAAACG GTCATGGTGT



 


51
AGAAATTGTT CATCTCCTCA TAGCTGAcgg gGCGCACCGG ATGGGCGGTC


 


101
GGGCCTGCGT CTTCGGGGAA CTGGTTCTGG CGCAGCAGGC GGATGTTCTC


 


151
GATGCGGCGC ACGGCGCGGC CGGCGCGGTC GCCGGAAAAC TCTTGGTCGC


 


201
GGAACACGGT CAGCCCTTCC TTCAGCGAAA GCTGGAACCA GTCGCGGCAG


 


251
GTTACGCGGT TGCCCGTCCA GTTGTGGAAA TATTCGTGTC CGACCACGGA


 


301
TTCAATGCCT TCGAAATCGG TATCGGTGGC GGTGCGGCTG TCGGCGAGGA


 


351
CGAACTTGGT GTTAAAAATG TTCAAACCCT TGTTTTCCAT CGCGCCCATA


 


401
TTGAAATCGC CTACGGCGAC GACCATGAaa atatccaagt cataTTCcaa


 


451
cCcgaagcgc gtttcgtcCc acttcatcgC gtTTTTTCAA cgaTTCCACG


 


501
GCAAAGCCGA CCTTGGGTTT GTCCGCTTCG GTGGTGTAAA ACTCGATTTT


 


551
GA






This corresponds to the amino acid sequence <SEQ ID 2154; ORF 664.ng>:










g664.pep




1
MIHPHHFRAF FINGHGVEIV HLLIADGAHR MGGRACVFGE LVLAQQADVL



 


51
DAAHGAAGAV AGKLLVAEHG QPFLQRKLEP VAAGYAVARP VVEIFVSDHG


 


101
FNAFEIGIGG GAAVGEDELG VKNVQTLVFH RAHIEIAYGD DHENIQVIFQ


 


151
PEARFVPLHR VFSTIPRQSR PWVCPLRWCK TRF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2155>:










m664.seq




1
GTGATACATC CGCACTACTT CCGCGCCTTT TTCATAAACG GTCATGGTGT



 


51
AGAAATTGTT CATCTCCTCA TAGCTGGCGG GGCGCACCGG ATGGGCGGTC


 


101
GGGCCTGCGT CTTCGGGGAA CTGGTGCTGG CGCAGCAGGC GGATGTTTTC


 


151
GATGCGGCGC ACGGCGCGGC TGGCGCGGTC GCCGGAAAAT TCTTGGTCGC


 


201
GGAACACGGT CAGCCCTTCC TTCAGCGAAA GCTGGAACCA GTCGCGGCAG


 


251
GTTACGCGGT TGCCCGTCCA GTTGTGGAAA TACTCGTGTC CGACCACGGA


 


301
TTCGATGCCT TCGAAATCGG TATCGGTGGC GGTGCGGCTG TCGGCAAGGA


 


351
CGAACTTGGT GTTAAAGATG TTCAAACCCT TGTTTTCCAT CGCGCCCATA


 


401
TTGAAATCGC CCACGGCGAC GACCATGAAA ATATCCAAGT CGTATTCCAA


 


451
ACCGAAGCGC GTTTCGTCCC ATTTCATCGC GTTTTT.CAA CGATTCCACG


 


501
GCAAAGCCGA CCTTGGGCTT GTCCGCTTCG GTGGTGTAAA ACTCGATTTT


 


551
GA






This corresponds to the amino acid sequence <SEQ ID 2156; ORF 664>:










m664.pep




1
VIHPHYFRAF FINGHGVEIV HLLIAGGAHR MGGRACVFGE LVLAQQADVF



 


51
DAAHGAAGAV AGKFLVAEHG QPFLQRKLEP VAAGYAVARP VVEILVSDHG


 


101
FDAFEIGIGG GAAVGKDELG VKDVQTLVFH RAHIEIAHGD DHENIQVVFQ


 


151
TEARFVPFHR VFXTIPRQSR PWACPLRWCK TRF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m664/g664 91.8% identity in 183 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2157>:










a664.seq




1
GTGATACATC CGCACCACTT CCGCGCCTTT TTCATAAACG GTCATGGTGT



 


51
AGAAATTGTT CATCTCCTCA TATCGGGCGG GGCGCACCGG ATGTGCGGTC


 


101
GGACCTGCGT CTTCGGGGAA CTGGTGCTGG CGCAGCAGGC GGATGTTTTC


 


151
GATACGGCGC ACGGCGCGGC TGGCGCGGTC GCCGGAAAAT TCTTGGTCGC


 


201
GGAACACGGT CAACCCTTCC TTCAGCGAAA GCTGGAACCA GTCGCGGCAG


 


251
GTCACGCGGT TGCCCGTCCA GTTGTGGAAA TATTCGTGTC CGACCACGGA


 


301
TTCGATGCCT TCAAAATCGG TATCGGTGGC GGTACGGCTG TCGGCAAGGA


 


351
CGAACTTGGT GTTAAAGATG TTCAAACCCT TGTTTTCCAT CGCACCCATA


 


401
TTGAAATCGC CCACGGCGAC GACCATGAAA ATATCCAAGT CGTATTCCAA


 


451
ACCGAAGCGC GTTTCGTCCC ACTTCATTGC GTTTTT.CAG CGATTCCACG


 


501
GCAAAGCCGA CCTTGGGCTT GTCCGCTTCG GTGGTGTAAA ACTCGATTTT


 


551
GA






This corresponds to the amino acid sequence <SEQ ID 2158; ORF 664.a>:










a664.pep




1
VIHPHHFRAF FINGHGVEIV HLLISGGAHR MCGRTCVFGE LVLAQQADVF



 


51
DTAHGAAGAV AGKFLVAEHG QPFLQRKLEP VAAGHAVARP VVEIFVSDHG


 


101
FDAFKIGIGG GTAVGKDELG VKDVQTLVFH RTHIEIAHGD DHENIQVVFQ


 


151
TEARFVPLHC VFXAIPRQSR PWACPLRWCK TRF*






m664/a664 92.9% identity in 183 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2159>:










g665.seq




1
atgaagtgGg acgaaacgcg cttcgGgttg GAAtatgact tggatatttT



 


51
CATGGTCGTC GCCGTAGGCG ATTTCAATAT GGGCGCGATG GAAAACAAGG


 


101
GTTTGAACAT TTTTAACACC AAGTTCGTCC TCGCCGACAG CCGCACCGCC


 


151
ACCGATACCG ATTTCGAAGG CATTGAATCC GTGGTCGGAC ACGAATATTT


 


201
CCACAACTGG ACGGGCAACC GCGTAACCTG CCGCGACTGG TTCCAGCTTT


 


251
CGCTGAAGGA AGGGCTGACC GTGTTCCGCG ACCAAGAGTT TTCCGGCGAC


 


301
CGCGCCGGCC GCGCCGTGCG CCGCATCGAG AACATCCGCC TGCTGCGCCA


 


351
GAACCAGTTC CCCGAAGACG CAGGCCCGAC CGCCCATCCG GTGCGCcccg


 


401
TCAGCTATGA GGAGATGAAC AATTTCTACA CCATGACCGT TTATGAAAAA


 


451
GGCGCGGAAG TGGTGCGGAT GTATCATACC CTGCTCGGCG AAGAGGGCTT


 


501
CCAAAAAGGC ATGAAGCTAT ATTTCcaacg CCACGACGGA CAGGCAGTGA


 


551
CCTGCGACGA TTTCCGCGCG GCGatggcgg ATGCGAACGG CATCAATCTC


 


601
GACCAGTTCG CCTTGTGGTA CAGCCAGGCG GGCACGCCCG TTTTGGAAGC


 


651
CGAAGGCCGT CTGAAAAACA ATGTTTTCGA GTTAACCATT AAACAAACCG


 


701
TGCCGCCCAC GCCCGATATG GCGGACAAAC AGCCGATGAT GATTCCCGTC


 


751
AAAGTCGGGC TTCTGAACCG CAACGGCGAA GCGGTGGCAT TCGATTATCA


 


801
GGGCAAACGC GCAACCGAAG CCGTGTTGCT GATGACCGAA GCCGAACagg


 


851
CCTTCCCGCT CGAAGGTGTA ACCGAAGCCG TCGTTCCCTC GCTGCTGCGC


 


901
GGGTTCAGCG CGCCAGTGTA TCTGAACTAT CCGTACAGCG ACGACGACCT


 


951
GCTGCTCCTG CTCGCCCACG ACAGCGACGC TTTCACGTGC TGGGAAGCCG


 


1001
CCCAAACGCT CTACCGTCGC GCCGTCGCCG CCAACCTTGC CGCGCTTTCA


 


1051
GACGGCATCG GGTTGCCGAA ACACGAAAAA CTGCTTGCCG CCGTCGAAAA


 


1101
AGTCATTTCA GACGACCTCT TGGACAACGC CTTCAAAGCC CTGCTTTTGG


 


1151
GCGTGCCGTC CGAAGCCGAa ctGTGGGACG GCACGGAAAA CATcgaCCCG


 


1201
CTGCGCTACC ATCAGGCGCG CGAAGCCTTG TTGGATACGC TTGCCGtcCG


 


1251
CttcctgcCG AAATGGCACG AATTGGaccg tcaggcggcg aagCAggaaa


 


1301
accaaagtTA CGAATACAGC CCCGAAACCG CCGACTGGCG CACGCTGCGC


 


1351
AACGTCTGCC GCGCCTtcgt cctGCGCGCC GACCCCGCGC acatcgAAAC


 


1401
TGTTGCCGAA Aaatacggcg AAATGGCGCA AAACATGACC CACGAATGGG


 


1451
GCATCCTGTC CGCCGTCAAC GGCAACGAAA GCGATACGCG CAACTGCCTG


 


1501
CTGGCGCAGT TTGCCGAcaa gTtttcAGAC GACGCGCTGG TGATGGACAA


 


1551
ATATTTCGCC CTTATCGGCT CAAGccgccg cagCGACACC CTGCAACAGG


 


1601
TTCAAACCGC CTTGCAGCAT CCGAAATTCA GTCTCGAAAA CCCCAACAAA


 


1651
GCCCGTTCGC TCATCGGCAG CTTCAGCCGC AACGTCCCGC ATTTTCACGC


 


1701
ACAAGACGGC AGCGGCTACC GCTTCATCGC CGACAAAGTC ATCGAAATCG


 


1751
ACCGCTTCAA cCCGCAggtc gccGCCCGCC TGGTGCAGGC GTTCAACCTC


 


1801
TGCAACAAGC TCGAGCCGCA CCGCAAAAAC TTgGTGAAAC AAGAATTGCA


 


1851
GTGCATTCGG GCGCAGGAAG GATTGTCGAA AGacGTGGGC GAaatcgtCG


 


1901
GCAAGATTTT GGGTTGA






This corresponds to the amino acid sequence <SEQ ID 2160; ORF 665.ng>:










g665.pep




1
MKWDETRFGL EYDLDIFMVV AVGDFNMGAM ENKGLNIFNT KFVLADSRTA



 


51
TDTDFEGIES VVGHEYFHNW TGNRVTCRDW FQLSLKEGLT VFRDQEFSGD


 


101
RAGRAVRRIE NIRLLRQNQF PEDAGPTAHP VRPVSYEEMN NFYTMTVYEK


 


151
GAEVVRMYHT LLGEEGFQKG MKLYFQRHDG QAVTCDDFRA AMADANGINL


 


201
DQFALWYSQA GTPVLEAEGR LKNNVFELTI KQTVPPTPDM ADKQPMMIPV


 


251
KVGLLNRNGE AVAFDYQGKR ATEAVLLMTE AEQAFPLEGV TEAVVPSLLR


 


301
GFSAPVYLNY PYSDDDLLLL LAHDSDAFTC WEAAQTLYRR AVAANLAALS


 


351
DGIGLPKHEK LLAAVEKVIS DDLLDNAFKA LLLGVPSEAE LWDGTENIDP


 


401
LRYHQAREAL LDTLAVRFLP KWHELDRQAA KQENQSYEYS PETADWRTLR


 


451
NVCRAFVLRA DPAHIETVAE KYGEMAQNMT HEWGILSAVN GNESDTRNCL


 


501
LAQFADKFSD DALVMDKYFA LIGSSRRSDT LQQVQTALQH PKFSLENPNK


 


551
ARSLIGSFSR NVPHFHAQDG SGYRFIADKV IEIDRFNPQV AARLVQAFNL


 


601
CNKLEPHRKN LVKQELQCIR AQEGLSKDVG EIVGKILG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2161>:










m665.seq




1
ATGAAATGGG ACGAAACGCG CTTCGGTTTG GAATACGACT TGGATATTTT



 


51
CATGGTCGTC GCCGTGGGCG ATTTCAATAT GGGCGCGATG GAAAACAAGG


 


101
GTTTGAACAT CTTTAACACC AAGTTCGTCC TTGCCGACAG CCGCACCGCC


 


151
ACCGATACCG ATTTCGAAGG CATCGAATCC GTGGTCGGAC ACGAGTATTT


 


201
CCACAACTGG ACGGGCAACC GCGTAACCTG CCGCGACTGG TTCCAGCTTT


 


251
CGCTGAAGGA AGGGCTGACC GTGTTCCGCG ACCAAGAATT TTCCGGCGAC


 


301
CGCGCCAGCC GCGCCGTGCG CCGCATCGAA AACATCCGCC TGCTGCGCCA


 


351
GCACCAGTTC CCCGAAGACG CAGGCCCGAC CGCCCATCCG GTGCGCCCCG


 


401
CCAGCTATGA GGAGATGAAC AATTTCTACA CCATGACCGT TTATGAAAAA


 


451
GGCGCGGAAG TAGTGCGGAT GTATCACACC CTGCTCGGCG AAGAGGGCTT


 


501
CCAGAAAGGC ATGAAGCTCT ATTTCCAACG CCACGACGGA CAGGCCGTTA


 


551
CCTGCGACGA TTTCCGCGCG GCGATGGCGG ACGCGAACGG CATCAATCTC


 


601
GACCAGTTCG CCTTGTGGTA CAGCCAGGCG GGCACGCCCG TTTTGGAAGC


 


651
GGAAGGTCGT CTGAAAAACA ATATTTTCGA GTTGACCGTC AAACAAACCG


 


701
TGCCGCCCAC GCCCGATATG ACGGATAAAC AGCCGATGAT GATTCCCGTC


 


751
AAGGTCGGGC TGCTGAACCG CAACGGCGAA GCGGTGGCAT TCGACTATCA


 


801
GGGCAAACGC GCGACCGAAG CCGTGTTGCT GCTGACCGAA GCCGAACAGA


 


851
CCTTCCTGCT CGAAGGCGTA ACCGAAGCCG TCGTTCCCTC GCTGCTGCGC


 


901
GGGTTCAGCG CGCCGGTGCA TCTGAACTAT CCGTACAGCG ACGACGACCT


 


951
GCTGCTCCTG CTCGCCCATG ACAGCGACGC CTTCACGCGC TGGGAAGCCG


 


1001
CCCAAACGCT CTACCGCCGC GCCGTCGCCG CCAACCTTGC CACGCTTTCA


 


1051
GACGGCGTTG AGCTGCCGAA ACACGAAAAA CTGCTTGCCG CCGTCGAAAA


 


1101
AGTCATTTCA GACGACCTCT TAGACAACGC CTTCAAAGCC CTGCTTTTGG


 


1151
GCGTGCCATC CGAAGCCGAG CTGTGGGACG GCGCAGAAAA CATCGACCCG


 


1201
CTGCGCTACC ATCAGGCGCG CGAAGCCTTG TTGGATACGC TTGCCGTCCA


 


1251
CTTCCTGCCG AAATGGCACG AATTGAACCG TCAGGCGGCG AAGCAGGAAA


 


1301
ACCAAAGCTA CGAATACAGC CCCGAAGCCG CCGGCTGGCG CACGCTGCGC


 


1351
AACGTCTGCC GCGCCTTTGT CCTGCGCGCC GACCCCGCGC ACATCGAAAC


 


1401
CGTTGCCGAA AAATACGGCG AAATGGCGCA AAACATGACC CACGAATGGG


 


1451
GCATCCTGTC CGCCGTCAAC GGCAACGAAA GCGATACGCG CAACCGCCTG


 


1501
CTGGCGCAGT TTGCCGACAA GTTTTCAGAC GACGCGCTGG TGATGGACAA


 


1551
ATATTTTGCC CTCGTCGGCT CAAGCCGCCG CAGCGACACC CTGCAACAGG


 


1601
TTCGAACCGC CTTGCAGCAT CCGAAATTCA GCCTCGAAAA CCCCAACAAA


 


1651
GCCCGTTCGC TCATCGGCAG CTTCAGCCGC AACGTCCCGC ATTTCCACGC


 


1701
AGAAGACGGC AGCGGCTACC GCTTCATCGC CGACAAAGTC ATCGAAATCG


 


1751
ACCGCTTCAA CCCGCAGGTC GCCGCCCGCT TAGTGCAGGC GTTCAACCTC


 


1801
TGCAACAAGC TCGAGCCGCA CCGCAAAAAC TTGGTGAAAC AAGCATTGCA


 


1851
GCGCATTCGG GCGCAGGAAG GATTGTCGAA AGACGTGGGC GAAATCGTCG


 


1901
GCAAAATTTT GGATTGA






This corresponds to the amino acid sequence <SEQ ID 2162; ORF 665>:










m665.pep




1
MKWDETRFGL EYDLDIFMVV AVGDFNMGAM ENKGLNIFNT KFVLADSRTA



 


51
TDTDFEGIES VVGHEYFHNW TGNRVTCRDW FQLSLKEGLT VFRDQEFSGD


 


101
RASRAVRRIE NIRLLRQHQF PEDAGPTAHP VRPASYEEMN NFYTMTVYEK


 


151
GAEVVRMYHT LLGEEGFQKG MKLYFQRHDG QAVTCDDFRA AMADANGINL


 


201
DQFALWYSQA GTPVLEAEGR LKNNIFELTV KQTVPPTPDM TDKQPMMIPV


 


251
KVGLLNRNGE AVAFDYQGKR ATEAVLLLTE AEQTFLLEGV TEAVVPSLLR


 


301
GFSAPVHLNY PYSDDDLLLL LAHDSDAFTR WEAAQTLYRR AVAANLATLS


 


351
DGVELPKHEK LLAAVEKVIS DDLLDNAFKA LLLGVPSEAE LWDGAENIDP


 


401
LRYHQAREAL LDTLAVHFLP KWHELNRQAA KQENQSYEYS PEAAGWRTLR


 


451
NVCRAFVLRA DPAHIETVAE KYGEMAQNMT HEWGILSAVN GNESDTRNRL


 


501
LAQFADKFSD DALVMDKYFA LVGSSRRSDT LQQVRTALQH PKFSLENPNK


 


551
ARSLIGSFSR NVPHFHAEDG SGYRFIADKV IEIDRFNPQV AARLVQAFNL


 


601
CNKLEPHRKN LVKQALQRIR AQEGLSKDVG EIVGKILD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m665/g665 96.1% identity in 637 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2163>:










a665.seq




1
ATGAAGTGGG ACGAAACGCG CTTCGGTTTG GAATACGACT TGGATATTTT



 


51
CATGGTCGTC GCCGTGGGCG ATTTCAATAT GGGTGCGATG GAAAACAAGG


 


101
GTTTGAACAT CTTTAACACC AAGTTCGTCC TTGCCGACAG CCGTACCGCC


 


151
ACCGATACCG ATTTTGAAGG CATCGAATCC GTGGTCGGAC ACGAATATTT


 


201
CCACAACTGG ACGGGCAACC GCGTGACCTG CCGCGACTGG TTCCAGCTTT


 


251
CGCTGAAGGA AGGGTTGACC GTGTTCCGCG ACCAAGAATT TTCCGGCGAC


 


301
CGCGCCAGCC GCGCCGTGCG CCGTATCGAA AACATCCGCC TGCTGCGCCA


 


351
GCACCAGTTC CCCGAAGACG CAGGTCCGAC CGCACATCCG GTGCGCCCCG


 


401
CCCGATATGA GGAGATGAAC AATTTCTACA CCATGACCGT TTATGAAAAA


 


451
GGCGCGGAAG TGGTGCGGAT GTATCACACC TTGCTCGGCG AAGAGGGCTT


 


501
CCAAAAAGGT ATGAAGCTCT ATTTCCAACG CCACGACGGA CAGGCTGTTA


 


551
CCTGCGACGA TTTCCGCGCG GCGATGGTGG ACGCGAACGG CATCAACCTC


 


601
GACCAATTCG CCTTGTGGTA CAGCCAAGCA GGTACGCCGG TTTTAGATGC


 


651
TCAAGGGCGT CTGAAAAACA ATGTGTTCGA GTTAACCATC AAACAAACCG


 


701
TGCCGCCCAC GCCCGATATG GCGGACAAAC AGCCGATGAT GATTCCCGTC


 


751
AAAATCGGGC TGCTGAACTG CAACGGCGAA GCGGTGGCAT TTGATTATCA


 


801
GGGCAAACGC GCGACCGAAG CCGTGTTGCT GCTGACCGAA GCCGAACAGA


 


851
CCTTCCAGTT CGAAAGCGTA ACCGAAGCCG TCGTTCCCTC GCTGCTGCGC


 


901
GGGTTCAGCG CGCCGGTGCA TCTGAACTAT CCGTACAGCG ACGACGACCT


 


951
GCTGCTTCTG CTCGCCCATG ACAGCGACGC CTTCACGCGC TGGGAAGCCG


 


1001
CACAAACGCT CTACCGCCGT GCCGTCGCCG CCAACCTTGC CGCGCTTTCA


 


1051
GACGGCGTCG AGTTGCCGAA ACACGAAAAA CTGCTTGCCG CCGTCGAAAA


 


1101
AGTCATTTCA GACGACCTCT TAGACAACGC TTTCAAAGCC CTGCTTTTGG


 


1151
GTGTGCCGTC TGAAGCCGAG CTGTGGGACG GCGCGGAAAA CATCGACCCG


 


1201
CTGCGCTACC ATCAGGCGCG CGAAGCCTTG TTGGATATAC TTGCCGTCCG


 


1251
CTTTCTGCCG AAATGGCACG AATTGAACCG TCAGGCGGCG AAGCAGGAAA


 


1301
ACCAAAGCTA CGAGTACAGC CCCGAAGCCG CCGGTTGGCG CACGCTGCGC


 


1351
AATGTCTGCC GCGCCTTCGT CCTGCGCGCC GATCCCGCGC ACATCGAAAC


 


1401
CGTTGCCGAG AAATACGCCG AAATGGCGCA AAACATGACC CACGAATGGG


 


1451
GCATCCTGTC CGCCGTCAAC GGCAACGAAA GCGATACGCG CAACCGCCTG


 


1501
CTGGCGCAGT TTGCCGACAA GTTTTCAGAC GACGCGCTGG TGATGGACAA


 


1551
ATATTTCGCC CTCGTCGGCT CAAGCCGCCG CAGCGACACC CTGCAACAGG


 


1601
TTCAAACCGC CTTGCAGCAT CCGAAGTTCA GCCTCGAAAA TCCCAACAAA


 


1651
GCCCGCTCGC TCATCGGCAG CTTCAGCCGC AACGTCCCGC ATTTCCACGC


 


1701
AGAAGACGGC AGCGGCTACC GCTTCATCGC CGACAAAGTC ATCGAAATCG


 


1751
ACCGCTTTAA CCCGCAGGTC GCCGCCCGCC TGGTGCAGGC GTTCAACCTC


 


1801
TGCAACAAGC TCGAGCCGCA CCGCAAAAAC TTGGTGAAAC AAGCATTGCA


 


1851
GCGCATTCGG GCGCAGGAAG GATTGTCGAA AGACGTGGGC GAAATCGTCG


 


1901
GCAAAATTTT GGATTGA






This corresponds to the amino acid sequence <SEQ ID 2164; ORF 665.a>:










a665.pep




1
MKWDETRFGL EYDLDIFMVV AVGDFNMGAM ENKGLNIFNT KFVLADSRTA



 


51
TDTDFEGIES VVGHEYFHNW TGNRVTCRDW FQLSLKEGLT VFRDQEFSGD


 


101
RASRAVRRIE NIRLLRQHQF PEDAGPTAHP VRPARYEEMN NFYTMTVYEK


 


151
GAEVVRMYHT LLGEEGFQKG MKLYFQRHDG QAVTCDDFRA AMVDANGINL


 


201
DQFALWYSQA GTPVLDAQGR LKNNVFELTI KQTVPPTPDM ADKQPMMIPV


 


251
KIGLLNCNGE AVAFDYQGKR ATEAVLLLTE AEQTFQFESV TEAVVPSLLR


 


301
GFSAPVHLNY PYSDDDLLLL LAHDSDAFTR WEAAQTLYRR AVAANLAALS


 


351
DGVELPKHEK LLAAVEKVIS DDLLDNAFKA LLLGVPSEAE LWDGAENIDP


 


401
LRYHQAREAL LDILAVRFLP KWHELNRQAA KQENQSYEYS PEAAGWRTLR


 


451
NVCRAFVLRA DPAHIETVAE KYAEMAQNMT HEWGILSAVN GNESDTRNRL


 


501
LAQFADKFSD DALVMDKYFA LVGSSRRSDT LQQVQTALQH PKFSLENPNK


 


551
ARSLIGSFSR NVPHFHAEDG SGYRFIADKV IEIDRFNPQV AARLVQAFNL


 


601
CNKLEPHRKN LVKQALQRIR AQEGLSKDVG EIVGKILD*






m665/a665 97.3% identity in 638 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2165>:










g665-1.seq




1
ATGAGCAAAA CCGTCCGTTA TCTGAAAGAT TACCAAACGC CTGCCTACCG



 


51
CATTCTTGAA ACCGAACTGC ATTTCGACAT TGCCGAACCG CAAACCGTCG


 


101
TGAAGTCGCG TTTGACGGTC GAGCCGCAGA GGGCGGGCGA GCCGCTGGTG


 


151
TTGGACGGTT CGGCAAAACT CTTGTCCGTC AAAATCAACG GCGCGGCGGC


 


201
GGATTATGTG TTGGAAGGCG AGACGCTGAC GATTGCAGAC GTACCGTCCG


 


251
AACGCTTCAC CGTCGAAGTG GAAACCGAAA TCCTGCCGGC GGAAAACAAA


 


301
TCGCTGATGG GGCTGTATGC TTCCGGCGGC AATCTGTTTA CCCAGTGCGA


 


351
GCCGGAGGGC TTCCGCAAAA TCACGTTCTA CATCGACCGT CCGGATGTGA


 


401
TGTCCAAGTT CACGACCACC ATCGTCGCGG ACAAAAAACG CTATCCCGTT


 


451
TTGCTTTCCA ACGGCAACAA AATCGACGGC GGCGAGTTTT CAGACGGCCG


 


501
CCATTGGGTG AAATGGGAAG ACCCGTTTGC CAAACCGAGT TATCTGTTTG


 


551
CTTTGGTCGC GGGCGATTTG GCGGTAACGG AAGACCGTTT CACCACCATG


 


601
AGCGGCAGAA ACGTCAAAAT CGAGTTTTAC ACCACCGAAG CGGACAAACC


 


651
CAAGGTCGGC TTTGCCGTGG AATCGTTGAA AAACGCGATG AAGTGGGACG


 


701
AAACGCGCTT CGGGTTGGAA TATGACTTGG ATATTTTCAT GGTCGTCGCC


 


751
GTAGGCGATT TCAATATGGG CGCGATGGAA AACAAGGGTT TGAACATTTT


 


801
TAACACCAAG TTCGTCCTCG CCGACAGCCG CACCGCCACC GATACCGATT


 


851
TCGAAGGCAT TGAATCCGTG GTCGGACACG AATATTTCCA CAACTGGACG


 


901
GGCAACCGCG TAACCTGCCG CGACTGGTTC CAGCTTTCGC TGAAGGAAGG


 


951
GCTGACCGTG TTCCGCGACC AAGAGTTTTC CGGCGACCGC GCCGGCCGCG


 


1001
CCGTGCGCCG CATCGAGAAC ATCCGCCTGC TGCGCCAGAA CCAGTTCCCC


 


1051
GAAGACGCAG GCCCGACCGC CCATCCGGTG CGCCCCGTCA GCTATGAGGA


 


1101
GATGAACAAT TTCTACACCA TGACCGTTTA TGAAAAAGGC GCGGAAGTGG


 


1151
TGCGGATGTA TCATACCCTG CTCGGCGAAG AGGGCTTCCA AAAAGGCATG


 


1201
AAGCTATATT TCCAACGCCA CGACGGACAG GCAGTGACCT GCGACGATTT


 


1251
CCGCGCGGCG ATGGCGGATG CGAACGGCAT CAATCTCGAC CAGTTCGCCT


 


1301
TGTGGTACAG CCAGGCGGGC ACGCCCGTTT TGGAAGCCGA AGGCCGTCTG


 


1351
AAAAACAATG TTTTCGAGTT AACCATTAAA CAAACCGTGC CGCCCACGCC


 


1401
CGATATGGCG GACAAACAGC CGATGATGAT TCCCGTCAAA GTCGGGCTTC


 


1451
TGAACCGCAA CGGCGAAGCG GTGGCATTCG ATTATCAGGG CAAACGCGCA


 


1501
ACCGAAGCCG TGTTGCTGAT GACCGAAGCC GAACAGGCCT TCCCGCTCGA


 


1551
AGGTGTAACC GAAGCCGTCG TTCCCTCGCT GCTGCGCGGG TTCAGCGCGC


 


1601
CAGTGTATCT GAACTATCCG TACAGCGACG ACGACCTGCT GCTCCTGCTC


 


1651
GCCCACGACA GCGACGCTTT CACGTGCTGG GAAGCCGCCC AAACGCTCTA


 


1701
CCGTCGCGCC GTCGCCGCCA ACCTTGCCGC GCTTTCAGAC GGCATCGGGT


 


1751
TGCCGAAACA CGAAAAACTG CTTGCCGCCG TCGAAAAAGT CATTTCAGAC


 


1801
GACCTCTTGG ACAACGCCTT CAAAGCCCTG CTTTTGGGCG TGCCGTCCGA


 


1851
AGCCGAACTG TGGGACGGCA CGGAAAACAT CGACCCGCTG CGCTACCATC


 


1901
AGGCGCGCGA AGCCTTGTTG GATACGCTTG CCGTCCGCTT CCTGCCGAAA


 


1951
TGGCACGAAT TGGACCGTCA GGCGGCGAAG CAGGAAAACC AAAGTTACGA


 


2001
ATACAGCCCC GAAACCGCCG ACTGGCGCAC GCTGCGCAAC GTCTGCCGCG


 


2051
CCTTCGTCCT GCGCGCCGAC CCCGCGCACA TCGAAACTGT TGCCGAAAAA


 


2101
TACGGCGAAA TGGCGCAAAA CATGACCCAC GAATGGGGCA TCCTGTCCGC


 


2151
CGTCAACGGC AACGAAAGCG ATACGCGCAA CTGCCTGCTG GCGCAGTTTG


 


2201
CCGACAAGTT TTCAGACGAC GCGCTGGTGA TGGACAAATA TTTCGCCCTT


 


2251
ATCGGCTCAA GCCGCCGCAG CGACACCCTG CAACAGGTTC AAACCGCCTT


 


2301
GCAGCATCCG AAATTCAGTC TCGAAAACCC CAACAAAGCC CGTTCGCTCA


 


2351
TCGGCAGCTT CAGCCGCAAC GTCCCGCATT TTCACGCACA AGACGGCAGC


 


2401
GGCTACCGCT TCATCGCCGA CAAAGTCATC GAAATCGACC GCTTCAACCC


 


2451
GCAGGTCGCC GCCCGCCTGG TGCAGGCGTT CAACCTCTGC AACAAGCTCG


 


2501
AGCCGCACCG CAAAAACTTG GTGAAACAAG AATTGCAGTG CATTCGGGCG


 


2551
CAGGAAGGAT TGTCGAAAGA CGTGGGCGAA ATCGTCGGCA AGATTTTGGG


 


2601
TTGA






This corresponds to the amino acid sequence <SEQ ID 2166; ORF 665-1.ng>:










g665-1.pep




1
MSKTVRYLKD YQTPAYRILE TELHFDIAEP QTVVKSRLTV EPQRAGEPLV



 


51
LDGSAKLLSV KINGAAADYV LEGETLTIAD VPSERFTVEV ETEILPAENK


 


101
SLMGLYASGG NLFTQCEPEG FRKITFYIDR PDVMSKFTTT IVADKKRYPV


 


151
LLSNGNKIDG GEFSDGRHWV KWEDPFAKPS YLFALVAGDL AVTEDRFTTM


 


201
SGRNVKIEFY TTEADKPKVG FAVESLKNAM KWDETRFGLE YDLDIFMVVA


 


251
VGDFNMGAME NKGLNIFNTK FVLADSRTAT DTDFEGIESV VGHEYFHNWT


 


301
GNRVTCRDWF QLSLKEGLTV FRDQEFSGDR AGRAVRRIEN IRLLRQNQFP


 


351
EDAGPTAHPV RPVSYEEMNN FYTMTVYEKG AEVVRMYHTL LGEEGFQKGM


 


401
KLYFQRHDGQ AVTCDDFRAA MADANGINLD QFALWYSQAG TPVLEAEGRL


 


451
KNNVFELTIK QTVPPTPDMA DKQPMMIPVK VGLLNRNGEA VAFDYQGKRA


 


501
TEAVLLMTEA EQAFPLEGVT EAVVPSLLRG FSAPVYLNYP YSDDDLLLLL


 


551
AHDSDAFTCW EAAQTLYRRA VAANLAALSD GIGLPKHEKL LAAVEKVISD


 


601
DLLDNAFKAL LLGVPSEAEL WDGTENIDPL RYHQAREALL DTLAVRFLPK


 


651
WHELDRQAAK QENQSYEYSP ETADWRTLRN VCRAFVLRAD PAHIETVAEK


 


701
YGEMAQNMTH EWGILSAVNG NESDTRNCLL AQFADKFSDD ALVMDKYFAL


 


751
IGSSRRSDTL QQVQTALQHP KFSLENPNKA RSLIGSFSRN VPHFHAQDGS


 


801
GYRFIADKVI EIDRFNPQVA ARLVQAFNLC NKLEPHRKNL VKQELQCIRA


 


851
QEGLSKDVGE IVGKILG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2167>:










m665-1.seq




1
ATGAGCAAAA CCGTGCATTA TCTCAAAGAC TATCAAACGC CCGCCTACCA



 


51
TATTCTCAAA ACCGATTTAC ATTTTGATAT TAATGAACCG CAAACCGTCG


 


101
TGAAGTCGCG TTTGACGGTT GAGCCGCAGA GGGTAGGGGA GCCGCTGGTG


 


151
TTGGACGGTT CGGCGAAACT CTTGTCCGTC AAAATCAACG GGGCGGCGGC


 


201
GGATTATGTG TTGGAAGGAG AGACGCTGAC GATTGCGGGC GTGCCGTCCG


 


251
AACGCTTCAC CGTCGAAGTG GAAACCGAAA TCCTGCCGGC GGAAAACAAA


 


301
TCGCTGATGG GGCTGTATGC TTCCGGCGGC AATTTGTTTA CCCAGTGCGA


 


351
GCCGGAGGGC TTCCGCAAAA TCACATTTTA CATCGACCGT CCGGATGTGA


 


401
TGTCCAAGTT CACCACCACC ATCGTCGCCG ACAAAAAACG CTATCCCGTT


 


451
TTGCTTTCCA ACGGCAACAA AATCGACGGC GGCGAGTTTT CAGACGGCCG


 


501
CCATTGGGTG AAATGGGAAG ACCCGTTTTC CAAACCGAGC TATCTGTTTG


 


551
CTTTGGTCGC GGGCGATTTG GCGGTAACGG AAGACTATTT CACCACCATG


 


601
AGCGGCAGAA ACGTCAAAAT CGAGTTTTAC ACCACCGAAG CGGACAAGCC


 


651
CAAGGTCGGC TTTGCCGTGG AATCGTTGAA AAACGCGATG AAATGGGACG


 


701
AAACGCGCTT CGGTTTGGAA TACGACTTGG ATATTTTCAT GGTCGTCGCC


 


751
GTGGGCGATT TCAATATGGG CGCGATGGAA AACAAGGGTT TGAACATCTT


 


801
TAACACCAAG TTCGTCCTTG CCGACAGCCG CACCGCCACC GATACCGATT


 


851
TCGAAGGCAT CGAATCCGTG GTCGGACACG AGTATTTCCA CAACTGGACG


 


901
GGCAACCGCG TAACCTGCCG CGACTGGTTC CAGCTTTCGC TGAAGGAAGG


 


951
GCTGACCGTG TTCCGCGACC AAGAATTTTC CGGCGACCGC GCCAGCCGCG


 


1001
CCGTGCGCCG CATCGAAAAC ATCCGCCTGC TGCGCCAGCA CCAGTTCCCC


 


1051
GAAGACGCAG GCCCGACCGC CCATCCGGTG CGCCCCGCCA GCTATGAGGA


 


1101
GATGAACAAT TTCTACACCA TGACCGTTTA TGAAAAAGGC GCGGAAGTAG


 


1151
TGCGGATGTA TCACACCCTG CTCGGCGAAG AGGGCTTCCA GAAAGGCATG


 


1201
AAGCTCTATT TCCAACGCCA CGACGGACAG GCCGTTACCT GCGACGATTT


 


1251
CCGCGCGGCG ATGGCGGACG CGAACGGCAT CAATCTCGAC CAGTTCGCCT


 


1301
TGTGGTACAG CCAGGCGGGC ACGCCCGTTT TGGAAGCGGA AGGTCGTCTG


 


1351
AAAAACAATA TTTTCGAGTT GACCGTCAAA CAAACCGTGC CGCCCACGCC


 


1401
CGATATGACG GATAAACAGC CGATGATGAT TCCCGTCAAG GTCGGGCTGC


 


1451
TGAACCGCAA CGGCGAAGCG GTGGCATTCG ACTATCAGGG CAAACGCGCG


 


1501
ACCGAAGCCG TGTTGCTGCT GACCGAAGCC GAACAGACCT TCCTGCTCGA


 


1551
AGGCGTAACC GAAGCCGTCG TTCCCTCGCT GCTGCGCGGG TTCAGCGCGC


 


1601
CGGTGCATCT GAACTATCCG TACAGCGACG ACGACCTGCT GCTCCTGCTC


 


1651
GCCCATGACA GCGACGCCTT CACGCGCTGG GAAGCCGCCC AAACGCTCTA


 


1701
CCGCCGCGCC GTCGCCGCCA ACCTTGCCAC GCTTTCAGAC GGCGTTGAGC


 


1751
TGCCGAAACA CGAAAAACTG CTTGCCGCCG TCGAAAAAGT CATTTCAGAC


 


1801
GACCTCTTAG ACAACGCCTT CAAAGCCCTG CTTTTGGGCG TGCCATCCGA


 


1851
AGCCGAGCTG TGGGACGGCG CAGAAAACAT CGACCCGCTG CGCTACCATC


 


1901
AGGCGCGCGA AGCCTTGTTG GATACGCTTG CCGTCCACTT CCTGCCGAAA


 


1951
TGGCACGAAT TGAACCGTCA GGCGGCGAAG CAGGAAAACC AAAGCTACGA


 


2001
ATACAGCCCC GAAGCCGCCG GCTGGCGCAC GCTGCGCAAC GTCTGCCGCG


 


2051
CCTTTGTCCT GCGCGCCGAC CCCGCGCACA TCGAAACCGT TGCCGAAAAA


 


2101
TACGGCGAAA TGGCGCAAAA CATGACCCAC GAATGGGGCA TCCTGTCCGC


 


2151
CGTCAACGGC AACGAAAGCG ATACGCGCAA CCGCCTGCTG GCGCAGTTTG


 


2201
CCGACAAGTT TTCAGACGAC GCGCTGGTGA TGGACAAATA TTTTGCCCTC


 


2251
GTCGGCTCAA GCCGCCGCAG CGACACCCTG CAACAGGTTC GAACCGCCTT


 


2301
GCAGCATCCG AAATTCAGCC TCGAAAACCC CAACAAAGCC CGTTCGCTCA


 


2351
TCGGCAGCTT CAGCCGCAAC GTCCCGCATT TCCACGCAGA AGACGGCAGC


 


2401
GGCTACCGCT TCATCGCCGA CAAAGTCATC GAAATCGACC GCTTCAACCC


 


2451
GCAGGTCGCC GCCCGCTTAG TGCAGGCGTT CAACCTCTGC AACAAGCTCG


 


2501
AGCCGCACCG CAAAAACTTG GTGAAACAAG CATTGCAGCG CATTCGGGCG


 


2551
CAGGAAGGAT TGTCGAAAGA CGTGGGCGAA ATCGTCGGCA AAATTTTGGA


 


2601
TTGA






This corresponds to the amino acid sequence <SEQ ID 2168; ORF 665-1>:










m665-1.pep




1
MSKTVHYLKD YQTPAYHILK TDLHFDINEP QTVVKSRLTV EPQRVGEPLV


 


51
LDGSAKLLSV KINGAAADYV LEGETLTIAG VPSERFTVEV ETEILPAENK


 


101
SLMGLYASGG NLFTQCEPEG FRKITFYIDR PDVMSKFTTT IVADKKRYPV


 


151
LLSNGNKIDG GEFSDGRHWV KWEDPFSKPS YLFALVAGDL AVTEDYFTTM


 


201
SGRNVKIEFY TTEADKPKVG FAVESLKNAM KWDETRFGLE YDLDIFMVVA


 


251
VGDFNMGAME NKGLNIFNTK FVLADSRTAT DTDFEGIESV VGHEYFHNWT


 


301
GNRVTCRDWF QLSLKEGLTV FRDQEFSGDR ASRAVRRIEN IRLLRQHQFP


 


351
EDAGPTAHPV RPASYEEMNN FYTMTVYEKG AEVVRMYHTL LGEEGFQKGM


 


401
KLYFQRHDGQ AVTCDDFRAA MADANGINLD QFALWYSQAG TPVLEAEGRL


 


451
KNNIFELTVK QTVPPTPDMT DKQPMMIPVK VGLLNRNGEA VAFDYQGKRA


 


501
TEAVLLLTEA EQTFLLEGVT EAVVPSLLRG FSAPVHLNYP YSDDDLLLLL


 


551
AHDSDAFTRW EAAQTLYRRA VAANLATLSD GVELPKHEKL LAAVEKVISD


 


601
DLLDNAFKAL LLGVPSEAEL WDGAENIDPL RYHQAREALL DTLAVHFLPK


 


651
WHELNRQAAK QENQSYEYSP EAAGWRTLRN VCRAFVLRAD PAHIETVAEK


 


701
YGEMAQNMTH EWGILSAVNG NESDTRNRLL AQFADKFSDD ALVMDKYFAL


 


751
VGSSRRSDTL QQVRTALQHP KFSLENPNKA RSLIGSFSRN VPHFHAEDGS


 


801
GYRFIADKVI EIDRFNPQVA ARLVQAFNLC NKLEPHRKNL VKQALQRIRA


 


851
QEGLSKDVGE IVGKILD*






m665-1/g665-1 96.1% identity in 866 aa overlap








The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2169>:










a665-1.seq




1
ATGAGCAAAA CCGTGCATTA TCTCAAAGAC TATCAAACGC CCGCCTACCA


 


51
TATTCTCAAA ACCGATTTAC ATTTTGATAT TAACGAACCG CAAACCATTG


 


101
TGAAGTCGCG TTTGACGGTC GAGCCGAAGA GGGTGGGAGA GCCGCTGGTG


 


151
TTGGACGGTT CGGCGAAACT CTTGTCCGTC AAAATCAACG GCGTGGCGGC


 


201
GGATTATGTG TTGGAAGGCG AGACGCTGAC GATTGCGGAC GTGCCGTCCG


 


251
AACGCTTCAC CGTCGAAGTG GAAACCGAAA TCCTGCCGGC GGAAAACAAA


 


301
TCGCTGATGG GGCTGTATGC GTCCGCCGGT AACCTGTTTA CCCAGTGCGA


 


351
GCCGGAGGGC TTCCGCAAAA TCACGTTCTA TATCGACCGT CCGGATGTCA


 


401
TGTCCAAGTT CACGACCACC ATCGTCGCGG ACAAAAAACG CTATCCCGTT


 


451
TTGCTCTCCA ACGGCAACAA AATCGACGGC GGCGAGTATT CAGACGGCCG


 


501
CCATTGGGTG AAATGGGAAG ACCCGTTTGC CAAACCGAGT TATCTGTTTG


 


551
CTTTGGTCGC GGGCGATTTG GCGGTCACGG AAGACTATTT CACCACCATG


 


601
AGCGGCAGAA ACGTCAAAAT CGAGTTTTAC ACCACCGAAG CGGACAAGCC


 


651
CAAGGTCGGC TTTGCCGTGG AATCGCTGAA AAACGCAATG AAGTGGGACG


 


701
AAACGCGCTT CGGTTTGGAA TACGACTTGG ATATTTTCAT GGTCGTCGCC


 


751
GTGGGCGATT TCAATATGGG TGCGATGGAA AACAAGGGTT TGAACATCTT


 


801
TAACACCAAG TTCGTCCTTG CCGACAGCCG TACCGCCACC GATACCGATT


 


851
TTGAAGGCAT CGAATCCGTG GTCGGACACG AATATTTCCA CAACTGGACG


 


901
GGCAACCGCG TGACCTGCCG CGACTGGTTC CAGCTTTCGC TGAAGGAAGG


 


951
GTTGACCGTG TTCCGCGACC AAGAATTTTC CGGCGACCGC GCCAGCCGCG


 


1001
CCGTGCGCCG TATCGAAAAC ATCCGCCTGC TGCGCCAGCA CCAGTTCCCC


 


1051
GAAGACGCAG GTCCGACCGC ACATCCGGTG CGCCCCGCCC GATATGAGGA


 


1101
GATGAACAAT TTCTACACCA TGACCGTTTA TGAAAAAGGC GCGGAAGTGG


 


1151
TGCGGATGTA TCACACCTTG CTCGGCGAAG AGGGCTTCCA AAAAGGTATG


 


1201
AAGCTCTATT TCCAACGCCA CGACGGACAG GCTGTTACCT GCGACGATTT


 


1251
CCGCGCGGCG ATGGTGGACG CGAACGGCAT CAACCTCGAC CAATTCGCCT


 


1301
TGTGGTACAG CCAAGCAGGT ACGCCGGTTT TAGATGCTCA AGGGCGTCTG


 


1351
AAAAACAATG TGTTCGAGTT AACCATCAAA CAAACCGTGC CGCCCACGCC


 


1401
CGATATGGCG GACAAACAGC CGATGATGAT TCCCGTCAAA ATCGGGCTGC


 


1451
TGAACTGCAA CGGCGAAGCG GTGGCATTTG ATTATCAGGG CAAACGCGCG


 


1501
ACCGAAGCCG TGTTGCTGCT GACCGAAGCC GAACAGACCT TCCAGTTCGA


 


1551
AAGCGTAACC GAAGCCGTCG TTCCCTCGCT GCTGCGCGGG TTCAGCGCGC


 


1601
CGGTGCATCT GAACTATCCG TACAGCGACG ACGACCTGCT GCTTCTGCTC


 


1651
GCCCATGACA GCGACGCCTT CACGCGCTGG GAAGCCGCAC AAACGCTCTA


 


1701
CCGCCGTGCC GTCGCCGCCA ACCTTGCCGC GCTTTCAGAC GGCGTCGAGT


 


1751
TGCCGAAACA CGAAAAACTG CTTGCCGCCG TCGAAAAAGT CATTTCAGAC


 


1801
GACCTCTTAG ACAACGCTTT CAAAGCCCTG CTTTTGGGTG TGCCGTCTGA


 


1851
AGCCGAGCTG TGGGACGGCG CGGAAAACAT CGACCCGCTG CGCTACCATC


 


1901
AGGCGCGCGA AGCCTTGTTG GATATACTTG CCGTCCGCTT TCTGCCGAAA


 


1951
TGGCACGAAT TGAACCGTCA GGCGGCGAAG CAGGAAAACC AAAGCTACGA


 


2001
GTACAGCCCC GAAGCCGCCG GTTGGCGCAC GCTGCGCAAT GTCTGCCGCG


 


2051
CCTTCGTCCT GCGCGCCGAT CCCGCGCACA TCGAAACCGT TGCCGAGAAA


 


2101
TACGCCGAAA TGGCGCAAAA CATGACCCAC GAATGGGGCA TCCTGTCCGC


 


2151
CGTCAACGGC AACGAAAGCG ATACGCGCAA CCGCCTGCTG GCGCAGTTTG


 


2201
CCGACAAGTT TTCAGACGAC GCGCTGGTGA TGGACAAATA TTTCGCCCTC


 


2251
GTCGGCTCAA GCCGCCGCAG CGACACCCTG CAACAGGTTC AAACCGCCTT


 


2301
GCAGCATCCG AAGTTCAGCC TCGAAAATCC CAACAAAGCC CGCTCGCTCA


 


2351
TCGGCAGCTT CAGCCGCAAC GTCCCGCATT TCCACGCAGA AGACGGCAGC


 


2401
GGCTACCGCT TCATCGCCGA CAAAGTCATC GAAATCGACC GCTTTAACCC


 


2451
GCAGGTCGCC GCCCGCCTGG TGCAGGCGTT CAACCTCTGC AACAAGCTCG


 


2501
AGCCGCACCG CAAAAACTTG GTGAAACAAG CATTGCAGCG CATTCGGGCG


 


2551
CAGGAAGGAT TGTCGAAAGA CGTGGGCGAA ATCGTCGGCA AAATTTTGGA


 


2601
TTGA






This corresponds to the amino acid sequence <SEQ ID 2170; ORF 665-1.a>:










a665-1.pep




1
MSKTVHYLKD YQTPAYHILK TDLHFDINEP QTIVKSRLTV EPKRVGEPLV


 


51
LDGSAKLLSV KINGVAADYV LEGETLTIAD VPSERFTVEV ETEILPAENK


 


101
SLMGLYASAG NLFTQCEPEG FRKITFYIDR PDVMSKFTTT IVADKKRYPV


 


151
LLSNGNKIDG GEYSDGRHWV KWEDPFAKPS YLFALVAGDL AVTEDYFTTM


 


201
SGRNVKIEFY TTEADKPKVG FAVESLKNAM KWDETRFGLE YDLDIFMVVA


 


251
VGDFNMGAME NKGLNIFNTK FVLADSRTAT DTDFEGIESV VGHEYFHNWT


 


301
GNRVTCRDWF QLSLKEGLTV FRDQEFSGDR ASRAVRRIEN IRLLRQHQFP


 


351
EDAGPTAHPV RPARYEEMNN FYTMTVYEKG AEVVRMYHTL LGEEGFQKGM


 


401
KLYFQRHDGQ AVTCDDFRAA MVDANGINLD QFALWYSQAG TPVLDAQGRL


 


451
KNNVFELTIK QTVPPTPDMA DKQPMMIPVK IGLLNCNGEA VAFDYQGKRA


 


501
TEAVLLLTEA EQTFQFESVT EAVVPSLLRG FSAPVHLNYP YSDDDLLLLL


 


551
AHDSDAFTRW EAAQTLYRRA VAANLAALSD GVELPKHEKL LAAVEKVISD


 


601
DLLDNAFKAL LLGVPSEAEL WDGAENIDPL RYHQAREALL DILAVRFLPK


 


651
WHELNRQAAK QENQSYEYSP EAAGWRTLRN VCRAFVLRAD PAHIETVAEK


 


701
YAEMAQNMTH EWGILSAVNG NESDTRNRLL AQFADKFSDD ALVMDKYFAL


 


751
VGSSRRSDTL QQVQTALQHP KFSLENPNKA RSLIGSFSRN VPHFHAEDGS


 


801
GYRFIADKVI EIDRFNPQVA ARLVQAFNLC NKLEPHRKNL VKQALQRIRA


 


851
QEGLSKDVGE IVGKILD*






a665-1/m665-1 97.2% identity in 867 aa overlap








The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2171>:










g666.seq




1
ATGCTTTGTA TGAATTATCA ATCAAACTCA GGCGAAGGAG TGCTTGTAGC


 


51
TAAAACATAT TTATTGACTG CATTGATAAT GTCTATGGTA ATCTCCGGAT


 


101
GTCAAGTCAT CCATGCCAAT CAAGGTAAGG TTAATACTAA TTCTGCTGTC


 


151
ATCGCAGGTG CAGACGCTCA CACGCCTGAA CATGTAACGG GACTGACCGA


 


201
ACAAAAGCAG GTGATTGCAA GTGATTTTAT AGTAGCGTCA GCCAATCCAT


 


251
TAGCAACACA AGCTGGCTAT GATATCTTAA AGCAAGGCGG TAGCGCTGCA


 


301
GATGCGATGG TGGCGGTGCA GACGACACTA AGCTTGGTAG AGCCACAGTC


 


351
GTCAGGCTTG GGCGGTGGTG CATTTGTGTT GTATTGGGAC AATACCGCCA


 


401
AAACATTGAC CACATTTGAT GGGCGTGAGA CGGCACCGAT GCGTGCGACG


 


451
CCAGAATTAT TTTTGGATAA AGATGGTTAA CCATTGAAAT TTATGGAAGC


 


501
GGTGGTCGCT CGGTAGGTAC GCCTGCTATC CCTAAACTGA






This corresponds to the amino acid sequence <SEQ ID 2172; ORF 666.ng>:










g666.pep




1
MLCMNYQSNS GEGVLVAKTY LLTALIMSMV ISGCQVIHAN QGKVNTNSAV


 


51
IAGADAHTPE HVTGLTEQKQ VIASDFIVAS ANPLATQAGY DILKQGGSAA


 


101
DAMVAVQTTL SLVEPQSSGL GGGAFVLYWD NTAKTLTTFD GRETAPMRAT


 


151
PELFLDKDGX PLKFMEAVVA RXVRLLSLN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2173>:










m666.seq




1
ATGCCTTGTA TGAATCATCA ATCAAACTCA GGCGAAGGAG TGCTTGTGGC


 


51
TAAAACATAT TTATTGACTG CATTGATAAT GTCTATGACA ATCTCTGGAT


 


101
GTCAAGTCAT CCATGCCAAT CAAGGTAAGG TTAATACTCA TTCTGCTGTC


 


151
ATCACAGGTG CAGACGCTCA CACGCCTGAA CATGCAACGG GACTGACCGA


 


201
ACAAAAGCAG GTGATTGCAA GTGATTTTAT GGTAGCGTCA GCCAATCCAT


 


251
TAGCAACACA AGCTGGCTAT GATATCTTAA AGCAAGGCGG TAGCGCTGCA


 


301
GATGCGATGG TGGCGGTGCA GACGACACTA AGCTTGGTAG AGCCACAGTC


 


351
GTCAGGCTTG GGCGGTGGTG CATTTGTGTT GTATTGGGAT AATACCGCCA


 


401
AAACATTGAC CACATTTGAT GGGCGTGAGA CGGCACCGAT GCGTGCGACG


 


451
CCGGAATTAT TTTTGGATAA AGATGGTCAA CCATTGAAAT TTATGGAAGC


 


501
GGTGGTCGTG GTCGCTCGGT GGGTACGCCT GCTATCCCTA AACTGA






This corresponds to the amino acid sequence <SEQ ID 2174; ORF 666>:










m666.pep




1
MPCMNHQSNS GEGVLVAKTY LLTALIMSMT ISGCQVIHAN QGKVNTHSAV


 


51
ITGADAHTPE HATGLTEQKQ VIASDFMVAS ANPLATQAGY DILKQGGSAA


 


101
DAMVAVQTTL SLVEPQSSGL GGGAFVLYWD NTAKTLTTFD GRETAPMRAT


 


151
PELFLDKDGQ PLKFMEAVVV VARWVRLLSL N*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m666/g666 93.9% identity in 181 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2175>:










a666.seq




1
ATGCCTTGTA TGAATCATCA ATCAAACTCA GGCGAAGGAG TGCTTGTGGC


 


51
TAAAACATAT TTATTGACTG CATTGATAAT GTCTATGACA ATCTCTGGAT


 


101
GTCAAGTCAT CCATGCCAAT CAAGGTAAGG TTAATACTCA TTCTGCTGTC


 


151
ATCACAGGTG CAGACGCTCA CACGCCTGAA CATGCAACGG GACTGACCGA


 


201
ACAAAAGCAG GTGATTGCAA GTGATTTTAT GGTAGCGTCA GCCAATCCAT


 


251
TAGCAACACA AGCTGGCTAT GATATCTTAA AGCAAGGCGG TAGCGCTGCA


 


301
GATGCGATGG TGGCGGTGCA GACGACACTA AGCTTGGTAG AGCCACAGTC


 


351
GTCAGGCTTG GGCGGTGGTG CATTTGTGTT GTATTGGGAT AATACCGCCA


 


401
AAACATTGAC CACATTTGAT GGGCGTGAGA CGGCACCGAT GCGTGCGACG


 


451
CCGGAATTAT TTTTGGATAA AGATGGTCAA CCATTGAAAT TTATGGAAGC


 


501
GGTGGTCGTG GTCGCTCGGT GGGTACGCCT GCTATCCCTA AACTGA






This corresponds to the amino acid sequence <SEQ ID 2176; ORF 666.a>:










a666.pep




1
MPCMNHQSNS GEGVLVAKTY LLTALIMSMT ISGCQVIHAN QGKVNTHSAV


 


51
ITGADAHTPE HATGLTEQKQ VIASDFMVAS ANPLATQAGY DILKQGGSAA


 


101
DAMVAVQTTL SLVEPQSSGL GGGAFVLYWD NTAKTLTTFD GRETAPMRAT


 


151
PELFLDKDGQ PLKFMEAVVV VARWVRLLSL N*






m666/a666 100.0% identity in 181 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2177>:










g667.seq




1
atgcggtttg tcttctgttt gggcgGAGAG ATAGtttctg atccgtgtga


 


51
tttccAtttg gtattcgtcc gcgtcgaatc tgccgctgAc CAGAcagaaa


 


101
cgCAGataca tCaaatacgt attcacggca tcggtttcgc aatAAttgcg


 


151
GAtttccttc agcgtgcccg cgtgGAacgc ttcccacact ttgctgccgt


 


201
ccataCCCAg ctTGCCCGGA AAGCCGCACA GTTTcgcCat atcgtccagC


 


251
GGCACATTcg ccctcggctG GTAAAGCGCG AGCAAATCCA TCAAATCGCA


 


301
GTGGCGTTGG TGATAACGGC TGATGTAGTT GTTCCActtg AAATCGCGGC


 


351
tgtcgccgAA ATCGccgTCG CCCGTATCCC AATAGCGCGC GGCGTTGATG


 


401
CCGTATATCA GGGAGCGGTA ATGCAGTACG GGCAGGTCGA AACCGCCGCC


 


451
GTTCCAGCTG ACCAGTTGCG GCGTATGTTT TTCAACCAAT TCGAAAAACT


 


501
TGGCAATCAC GACTTCTTCG CCATCGTCCA TCTCGCCGAT GGTGCCGACA


 


551
TGAACCTTGT CCTGCCCCCA GCGCATACAG CAGGAAACCG CCACAACCTG


 


601
ATGGAGGTGG TGCTGCATAA AATCGCCGCC GGTCTGTGCG CGGCGTTTCT


 


651
GCTGCGCGAA CAGCACCACT TCGTCATCCG GCAGGGAAGA CGGCAAGTCA


 


701
TACAACGTAC GGATACCCTG CACATCGGGT ACGGTTTCAA TATCGAAAGC


 


751
CAAAATCGTA TTCATGGCAg tACCTTGCAT tcaAAAACAG ACtTGCGCCT


 


801
ATTgTgtcaT TAA






This corresponds to the amino acid sequence <SEQ ID 2178; ORF 667.ng>:










g667.pep




1
MRFVFCLGGE IVSDPCDFHL VFVRVESAAD QTETQIHQIR IHGIGFAIIA


 


51
DFLQRARVER FPHFAAVHTQ LARKAAQFRH IVQRHIRPRL VKREQIHQIA


 


101
VALVITADVV VPLEIAAVAE IAVARIPIAR GVDAVYQGAV MQYGQVETAA


 


151
VPADQLRRMF FNQFEKLGNH DFFAIVHLAD GADMNLVLPP AHTAGNRHNL


 


201
MEVVLHKIAA GLCAAFLLRE QHHFVIRQGR RQVIQRTDTL HIGYGFNIES


 


251
QNRIHGSTLH SKTDLRLLCH *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2179>:









m667.seq (PARTIAL)










1
ATGCGGCTTT TCCCCGGCTT GTGCGGACAG GTAATTCCGC ATCCGTTTGA



 


51
TTTCCATTTC GTATTCGTCC GCATCCAGCC TGCCGCTGAC CAGACAGAAA


 


101
CGCAGGTACA TCAGATAAGT GTTTGCCGCG TCGGTTTCGC AATAATTGCG


 


151
GATTTCCTTC AGCCTGCCCG TATGGAATGC CTCCCAAACC TTGCTGCCGT


 


201
CCATACCCAG CTTGCCCGGA AAACCGCACA GTTTCGCCAT ATCGTCCAGC


 


251
GGCACGTTTG CCCTCGGCTG GTAAAGCGCG AGCAAATCCA TCAAATCGCA


 


301
GTGGCGTTGG TGATAACGGC TGATGTAGTT GTTCCACTTG AAATCGCGGC


 


351
TGTCGCCGAA ATCGCCGTCG CCCATATCCC AATAGCGCGC GGCGTTGATG


 


401
CCGTATATCA GGGAGCGGTA ATGCAGTACG GGCAGATCGA AACCGCCGCC


 


451
GTTCCAACTG ACCAGTTGCG GCGTATGTTT TTCAATCAAT TCGAAAAATT


 


501
TAGCAATGAC CACTTCCTCG CCGTCATCCA TCTCGCCGAT GGTGCCGACA


 


551
TGTACTTTAT CCTGCCCCCA ACGCATGCAG CACGAAATCG CCACAACCTG


 


601
ATGAAGATGA TGCTGCATAA AATCGCCGCC CGTCTGAGCA CGGCGTTTGT


 


651
GCTGGGCAAT CAGCACCACT TG...






This corresponds to the amino acid sequence <SEQ ID 2180; ORF 667>:









m667.pep (partial)










1
MRLFPGLCGQ VIPHPFDFHF VFVRIQPAAD QTETQVHQIS VCRVGFAIIA



 


51
DFLQPARMEC LPNLAAVHTQ LARKTAQFRH IVQRHVCPRL VKREQIHQIA


 


101
VALVITADVV VPLEIAAVAE IAVAHIPIAR GVDAVYQGAV MQYGQIETAA


 


151
VPTDQLRRMF FNQFEKFSND HFLAVIHLAD GADMYFILPP THAARNRHNL


 


201
MKMMLHKIAA RLSTAFVLGN QHHL...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m667/g667 75.0% identity in 224 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2181>:










a667.seq




1
ATGCGGTTTG TCTTCTGTTT GGGCGGAGAG ATAGTTTCTG ATCCGCTTGA


 


51
TTTCCATTTC GTATTCGTCT GCGTCGAATC TGCCGCTGAC CAGACAGAAA


 


101
CGCAGATACA TCAGATAGGT ATTTACCGCA TCGGTTTCGC AATAATTGCG


 


151
GATTTCCTTC AGCCTGCCCG CGTGGAACGC CTCCCACACC TTGCTGCCGT


 


201
CCATACCCAG CTTGCCCGGA AAACCGCACA GTTTCGCCAT ATCGTCCAAC


 


251
GGCACATTCG CCCTCGGCTG GTAAAGCGCG AGCAAATCCA TCAAATCGCA


 


301
ATGACGTTGG TGGTAGCGGC TGATGTAGTT GTTCCACTTG AAATCGCGGC


 


351
TGTCGCCGAA ATCGCCGTCG CCCATATCCC AATAGCGCGC GGCGTTGATG


 


401
CCGTGTAGCA GCGAACGGTA ATGCAGAACC GGCAGGTCGA AACCGCCGCC


 


451
GTTCCAACTG ACCAGTTGCG GCGTATGTTT TTCAATCAAC TCGAAAAATT


 


501
TGGCGATAAC CACTTCCTCG CCGTCATCCA TCTCGCCGAT TGTACCGACA


 


551
TGGACTTTAT CCTGCCCCCA ACGCATGCAG CACGAAATCG CCACAATCTG


 


601
ATGAAGATGA TGCTGCATAA AATCCCCACC CGTCTGAGCA CGGCGTTTTT


 


651
GCTGGGCAAA CAGCACCACT TCATCGTCGG GCAGCGAGGA CGGCAAGTCA


 


701
TACAGCGTAC GGATACACTG CACATCGGGT ACGGTTTCAA TATCGAAAGC


 


751
CAAAATCGTG GTCATGACAG CACCTTGTAT TTAAAA.CAG ACTTGCGCCT


 


801
ATTGTGTCAT TAA






This corresponds to the amino acid sequence <SEQ ID 2182; ORF 667.a>:










a667.pep




1
MRFVFCLGGE IVSDPLDFHF VFVCVESAAD QTETQIHQIG IYRIGFAIIA


 


51
DFLQPARVER LPHLAAVHTQ LARKTAQFRH IVQRHIRPRL VKREQIHQIA


 


101
MTLVVAADVV VPLEIAAVAE IAVAHIPIAR GVDAV*QRTV MQNRQVETAA


 


151
VPTDQLRRMF FNQLEKFGDN HFLAVIHLAD CTDMDFILPP THAARNRHNL


 


201
MKMMLHKIPT RLSTAFLLGK QHHFIVGQRG RQVIQRTDTL HIGYGFNIES


 


251
QNRGHDSTLY LKXDLRLLCH *






m667/a667 79.0% identity in 224 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2183>:










g669.seq




1
ATGCGCCGCA TCGTTAAAAA ACACCAGCCC GTAAACGCGC CACATATCGT


 


51
TTTGGAAATT CGGATAATGA AACTGCATCG CGCGTTTGTC TTCCTTGGGC


 


101
GGAAACGTCC CCATCATCAT GACCGCAGCC TTCGGCGGCA ACACGGGATC


 


151
GAAGGGATGG GTTTCGATTT CAAGCAGATT TTCAGACACG TTCAATCCTC


 


201
CAACAGGCAA AGCGGCAGAC AGCCGGTTTG CACCAAACCG CCAAACACGG


 


251
CAAGCCTTCA AACAGCATTA TCACGCCCTG CCGTTTTCGG TTACAATGCC


 


301
GACATCAAAC GGATACTGTA A






This corresponds to the amino acid sequence <SEQ ID 2184; ORF 669.ng>:










g669.pep




1
MRRIVKKHQP VNAPHIVLEI RIMKLHRAFV FLGRKRPHHH DRSLRRQHGI


 


51
EGMGFDFKQI FRHVQSSNRQ SGRQPVCTKP PNTASLQTAL SRPAVFGYNA


 


101
DIKRIL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2185>:










m669.seq




1
ATGCGCCGCA TCATTAAAAA ACACCAGCCC ATAAACGCGC CACATATCGT


 


51
TTTGGAAATT CGGATAATGA AACTGCATCG CGCGTTTGTC TTCCTTGGGC


 


101
GGAAACGTCC CCATCATCAT GACAGCAGCC TTCGGCGGCA ACACGGGATC


 


151
GAAGGGATGG GTTTCGATTT CAAGCAGATT TTCAGACACG TTCAATCCTC


 


201
CAACAGGCAA AACGGCAGAC AGCCGGTTTG CACCAAACCG CCAAACACGG


 


251
CAAGCCTTCA AACAGCATTA TCACGCCCTG CCGTTTTCGG TTACAATGCC


 


301
GACATCAAAC GGATACTGTA A






This corresponds to the amino acid sequence <SEQ ID 2186; ORF 669>:










m669.pep




1
MRRIIKKHQP INAPHIVLEI RIMKLHRAFV FLGRKRPHHH DSSLRRQHGI


 


51
EGMGFDFKQI FRHVQSSNRQ NGRQPVCTKP PNTASLQTAL SRPAVFGYNA


 


101
DIKRIL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m669/g669 96.2% identity in 106 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2187>:










a669.seq




1
ATGCGCCGCA TCATTAAAAA ACACCAGCCC GTAAACGCGC CACATATCGT


 


51
TTTGGAAATT CGGATAATGA AACTGCATCG CGCGTTTGTC TTCCTTGGGC


 


101
GGAAACGTCC CCATCATCAT GACCGCAGCC TTCGGCGGCA ACACGGAATC


 


151
GAAGGGATGG GTTTCGATTT CAAGCAGATT TTCAGACACG TTCAATCCTC


 


201
CAACAGGCAA AACGGCAGAC AGCCGGTTTG CACCAAACCG CCAAACACGG


 


251
CAAGCCTTCA AACAGCATTA TCACGCCCTG CCGTTTTCGG TTACAATGCC


 


301
GACATCAAAC GGATACTGTA A






This corresponds to the amino acid sequence <SEQ ID 2188; ORF 669.a>:










a669.pep




1
MRRIIKKHQP VNAPHIVLEI RIMKLHRAFV FLGRKRPHHH DRSLRRQHGI


 


51
EGMGFDFKQI FRHVQSSNRQ NGRQPVCTKP PNTASLQTAL SRPAVFGYNA


 


101
DIKRIL*






m669/a669 98.1% identity in 106 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2189>:










g670.seq




1
ATGACTTGTT GCAGGAACTG CTTGGCGCGT TCGTGTTTCG GGTTGGTGAA


 


51
AAACGCTTCC GGCGTTTCGT CTTCAAGGAT TTGCCCTTTA TCGACGAAAA


 


101
TCACGCGGTC GGCAACTTCG CGGGCAAACC CCATTTCGTG GGTTACGCAC


 


151
ATCATCGTCA TGCCGCTTTC CGCCAAGTCT TTCATCACTT TCAACACTTC


 


201
GCCGACCATT TCGGGGTCGA GTGCGGAAGT CGGCTCGTCA AACAGCATCA


 


251
CGCGCGGCTC CATCGCCAGC CCGCGCGCAA TCGCCACGCG TTGCTGCTGG


 


301
CCGCCGGAAA GTTGGGAAGG GAAGGCGTCT TTTTTGTGTG CCAGTCCGAC


 


351
GCGTTCCAAA AGCTCCATTG CCTTTTTCTC CGCCTGTTCC GCATTTTGCC


 


401
CCTTAACCTT CATCGGTGCG AGGGTGATGT TGTCCAACAC GGTCAGGTGC


 


451
GGGTAG






This corresponds to the amino acid sequence <SEQ ID 2190; ORF 670.ng>:










g670.pep




1
MTCCRNCLAR SCFGLVKNAS GVSSSRICPL STKITRSATS RANPISWVTH


 


51
IIVMPLSAKS FITFNTSPTI SGSSAEVGSS NSITRGSIAS PRAIATRCCW


 


101
PPESWEGKAS FLCASPTRSK SSIAFFSACS AFCPLTFIGA RVMLSNTVRC


 


151
G*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2191>:










m670.seq




1
ATGACCTGTT GCAGGAACTG CTTGGCGCGT TCGTGTTTCG GGTTGGTAAA


 


51
AAACGCTTCG GGCGTTTCGT CTTCGAGGAT TTGCCCTTTA TCGACGAAAA


 


101
TCACGCGGTC GGCAACTTCG CGGGCAAACC CCATTTCGTG GGTTACGCAC


 


151
ATCATCGTCA TGCCGCTTTC TGCCAAGTCT TTCATCACTT TCAACACTTC


 


201
GCCGACCATT TCGGGGTCGA GTGCGGAGGT CGGTTCGTCA AACAACATTA


 


251
CGCGCGGTTC CATCGCCAAA CCGCGTGCAA TCGCCACGCG TTGCTGCTGG


 


301
CCGCCGGAAA GTTGGGAAGG GAAGGCGTCT TTTTTGTGTG CCAGTCCGAC


 


351
GCGTTCCAAA AGCTCCATTG CCTTTTTCTC CGCCTGTTCC GCATTTTGCC


 


401
CCTTAACCTT CATCGGTGCG AGGGTAATGT TTTCCAACAC GGTCAGGTGC


 


451
GGGTAG






This corresponds to the amino acid sequence <SEQ ID 2192; ORF 670>:










m670.pep




1
MTCCRNCLAR SCFGLVKNAS GVSSSRICPL STKITRSATS RANPISWVTH


 


51
IIVMPLSAKS FITFNTSPTI SGSSAEVGSS NNITRGSIAK PRAIATRCCW


 


101
PPESWEGKAS FLCASPTRSK SSIAFFSACS AFCPLTFIGA RVMFSNTVRC


 


151
G*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m670/g670 98.0% identity in 151 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2193>:










a670.seq




1
ATGACCTGTT GCAGGAACTG CTTGGCGCGT TCGTGTTTCG GGTTGGTAAA


 


51
AAACGCTTCC GGCGTTTCGT CTTCGAGGAT TTGCCCTTTA TCGACGAAAA


 


101
TCACGCGGTC GGCAACTTCG CGGGCAAACC CCATTTCGTG GGTTACGCAC


 


151
ATCATGGTCA TACCGCTTTC CGCCAAGTCT TTCATCACTT TCAACACTTC


 


201
GCCGACCATT TCGGGGTCGA GTGCGGAGGT CGGTTCGTCA AACAACATTA


 


251
CGCGCGGTTC CATCGCCAAA CCGCGTGCAA TCGCCACGCG TTGCTGCTGG


 


301
CCGCCGGAAA GTTGGGAAGG GAAGGCGTCT TTTTTGTGTG CCAGTCCGAC


 


351
GCGTTCCAAA AGTTCCATCG CTTTTTTCTC TGCCTGTTCC GCATTTTGAC


 


401
CTTTAACCTT CATCGGTGCG AGGGTAATGT TTTCCAACAC GGTCAGGTGC


 


451
GGGTAG






This corresponds to the amino acid sequence <SEQ ID 2194; ORF 670.a>:










a670.pep




1
MTCCRNCLAR SCFGLVKNAS GVSSSRICPL STKITRSATS RANPISWVTH


 


51
IMVIPLSAKS FITFNTSPTI SGSSAEVGSS NNITRGSIAK PRAIATRCCW


 


101
PPESWEGKAS FLCASPTRSK SSIAFFSACS AF*PLTFIGA RVMFSNTVRC


 


151
G*






m670/a670 98.0% identity in 151 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2195>:










g671.seq




1
ATGATCAGCA GGGTAACAAT CAAAACGCCT TTCAATGCAC CGAATACACC


 


51
GCCCAAAATG CGGTTGGCAA AGCCCAGACC GACCGCCGAA ACTGCGCCGG


 


101
TCAGCAGCGA ACGGAGCATT TTCTGGATCA GACAGGCAAT GACGAACAGG


 


151
GAAATGAATG ACAGagccaa TGCAAACAgg cggggTTGGA ACGaggCAAA


 


201
GGCGAGGTcg gcgaaggGTG CGGCaaAGAG TTTggcaaAA AAGAaggAAA


 


251
ccaccCATGC cACCATCgaa ccTGCTTCCG CAATCACGCC GCGCATCGTG


 


301
GAAATGACGA TGCAGGCGGC GATGACGGcg gAGGCGAGGA GGTCGGCAAT


 


351
GGGGAGGCTA TTCATTCGTT ACCTGGCCGG CGATGCCGTG CACGCGCAGT


 


401
TTGTTCAAAT CGCGTTCGGC ATCCCTTGCG TTTTTATAGT TGCTTGA






This corresponds to the amino acid sequence <SEQ ID 2196; ORF 671.ng>:










g671.pep




1
MISRVTIKTP FNAPNTPPKM RLAKPRPTAE TAPVSSERSI FWIRQAMTNR


 


51
EMNDRANANR RGWNEAKARS AKGAAKSLAK KKETTHATIE PASAITPRIV


 


101
EMTMQAAMTA EARRSAMGRL FIRYLAGDAV HAQFVQIAFG IPCVFIVA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2197>:










m671.seq




1
ATGACCAGCA GGGTAACAAT CAAAACGCCT TTCAATGCAC CGAATACGCC


 


51
GCCCAAAATG CGGTTGGCAA AGCCCAAACC GACCGCCGAA ACTGCGCTGG


 


101
TCAGCAGCGA ACGGAGCATT TTCTGGATCA GACAGGCAAT GACGAACAGG


 


151
GAAATGAACG ACAGAGCCAA TGCAAACAGG CGGGGTTGGA ACGAGGCAAA


 


201
GGCGAGGTCG GCGAAGGAGG CGGCAAAGAG TTTGGCGAAA AAGAAGGAAA


 


251
CCACCCATGC CGCCATTGAG CCTGCCTCCG CAATCACGCC GCGCATCGCG


 


301
GATAGCACGA TGCAGGCGGC GATGACGGCG GAGACGAGGA GGTCGGCAAT


 


351
GGGGAGGCTA TTCATTCGTT ACCTGACCGG CGATACCGTG TACGCGCAAT


 


401
TTGTTCAAAT CGCGTTCGGC ATCCCTTGCG TTTTTATAGT TGCTTGA






This corresponds to the amino acid sequence <SEQ ID 2198; ORF 671>:










m671.pep




1
MTSRVTIKTP FNAPNTPPKM RLAKPKPTAE TALVSSERSI FWIRQAMTNR



 


51
EMNDRANANR RGWNEAKARS AKEAAKSLAK KKETTHAAIE PASAITPRIA


 


101
DSTMQAAMTA ETRRSAMGRL FIRYLTGDTV YAQFVQIAFG IPCVFIVA*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m671/g671 91.9% identity in 148 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2199>:










a671.seq




1
ATGACCAGCA GGGTAATAAT CAAAATGCCT TTCAATGCAC CGAATACGCC



 


51
GCCCAAAATG CGGTTGGCAA AGCCCAAACC GACCGCCGAA ACTGCCCCGG


 


101
TCAGCAGCGA GCGGAGTATT TTCTGGATCA GACAGGCAAT GACGAATAGG


 


151
GAAATGAACG ACAGAGCCAA TGCAAACAGG CGGGGTTGGA ACGATGCAAA


 


201
GGCGATGTCG GCGAAGGGTG CGGCAAAGAG TTTGGCGAAA AAAAAGGCAA


 


251
CCACCCATGC CGCCATTGAG CCAGCCTCCG CAATCACGCC GCGCATCGCG


 


301
GATAGCACGA TGCAGGCGGC GATGATGGCG GAGACGAGGA GGTCGGCAAC


 


351
GGGGAGGTTA TTCATTCGTT ACCTGACCGG CGATACCGTG TACGCGCAAT


 


401
TTGTTCAAAT CGCGTTCGGC ATCCCTTGCG TTTTTATAGT TGCTTGA






This corresponds to the amino acid sequence <SEQ ID 2200; ORF 671.a>:










a671.pep




1
MTSRVIIKMP FNAPNTPPKM RLAKPKPTAE TAPVSSERSI FWIRQAMTNR



 


51
EMNDRANANR RGWNDAKAMS AKGAAKSLAK KKATTHAAIE PASAITPRIA


 


101
DSTMQAAMMA ETRRSATGRL FIRYLTGDTV YAQFVQIAFG IPCVFIVA*






m671/a671 93.9% identity in 148 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2201>:










g672.seq




1
ATGAGGAAAA TCCGCACCAA AATCTGCGGC ATCACCACAC CGGAAGACGC



 


51
ACTGTATGCC GCCCACGCCG GCGCAGACGC ATTGGGACTG GTTTTTTACC


 


101
CCCAAAGCCC CCGCGCTATC GACATCATTA AAGCACAAAA AATCGCCGCC


 


151
GCACTGCCGC CGTTTGTCAG CGTTGTCGCC CTTTTCGTCA ACGAAAGCGC


 


201
GCAAAACATC CGCCGCATCC TTGCCGAAGT GCCGATACAC ATCATCCAAT


 


251
TCCACGGCGA CGAAGACGAT GCATTCTGCC GGCAGTTCGA CCGCCCCTAT


 


301
ATTAAAGCCA TTCGTGTTCA GACGGCATCA GACATCCGAA ACGCCGCCAC


 


351
GCGCTTCCCC AACGCTCAGG CACTGCTGTT CGATGCCTAT CACCCTTCGG


 


401
AATACGGCGG CACCGGACAC CGCTTCGact GGacgctgtt ggcggAATAT


 


451
TCGGGCAAGC CGTGGGTGCT TGCCGGCGGG CTGACCCCTG AAAACGTCGG


 


501
CGAAGCCGTC CGCATCACCG GAGCGGAAGC GGTCGACGTA TCCGGCGGCG


 


551
TGGAAGCGTC TAAAGGCAAA AAAGACCCCG CCAAAGTCGC CGCCTTTATC


 


601
GCAACCGCCA ACCGCCTATC CCGTTAA






This corresponds to the amino acid sequence <SEQ ID 2202; ORF 672.ng>:










g672.pep




1
MRKIRTKICG ITTPEDALYA AHAGADALGL VFYPQSPRAI DIIKAQKIAA



 


51
ALPPFVSVVA LFVNESAQNI RRILAEVPIH IIQFHGDEDD AFCRQFDRPY


 


101
IKAIRVQTAS DIRNAATRFP NAQALLFDAY HPSEYGGTGH RFDWTLLAEY


 


151
SGKPWVLAGG LTPENVGEAV RITGAEAVDV SGGVEASKGK KDPAKVAAFI


 


201
ATANRLSR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2203>:










m672.seq




1
ATGAGGAAAA TCCGCACCAA AATCTGCGGC ATCACCACAC CGGAAGACGC



 


51
AGCTGCCGCC GCAGCGGCAG GTGCGGATGC CGTCGGGCTG GTCTTTTTCC


 


101
AAGGCAGCAG CCGGGCCGTC GATATTGCCC GCGCCAAAAA AATCACCGCC


 


151
GCACTGCCGC CGTTTGTCAG CGTTGTCGCC CTTTTCGTCA ACGAAAGCGC


 


201
GCAAAACATC CGCCGCATCC TTGCCGAAGT GCCGATACAC ATCATCCAAT


 


251
TCCACGGCGA CGAAGACGAC GCATTCTGCC GCCAGTTCCA CCGCCCCTAT


 


301
ATCAAAGCCA TTCGTGTTCA GACGGCATCA GACATCCGAA ACGCCGCCAC


 


351
GCGCTTCCCC GACGCTCAGG CACTGCTGTT CGATGCCTAC CATCCTTCGG


 


401
AATACGGCGG CACCGGAAAC CGCTTCGACT GGACGCTGCT GGCGGAATAT


 


451
TCGGGCAAAC CGTGGGTGCT TGCCGGCGGG CTGACCCCTG AAAACGTCGG


 


501
CGAAGCCGTC CGCATCACCG GAGCGGAATC GGTCGATGTA TCCGGCGGTG


 


551
TGGAAGCGTC TAAAGGCAAA AAAGATGCCG CCAAAGTCGC CGCCTTTATC


 


601
GCAACCGCCA ACCGCCTATC CCGTTAA






This corresponds to the amino acid sequence <SEQ ID 2204; ORF 672>:










m672.pep




1
MRKIRTKICG ITTPEDAAAA AAAGADAVGL VFFQGSSRAV DIARAKKITA



 


51
ALPPFVSVVA LFVNESAQNI RRILAEVPIH IIQFHGDEDD AFCRQFHRPY


 


101
IKAIRVQTAS DIRNAATRFP DAQALLFDAY HPSEYGGTGN RFDWTLLAEY


 


151
SGKPWVLAGG LTPENVGEAV RITGAESVDV SGGVEASKGK KDAAKVAAFI


 


201
ATANRLSR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m672/g672 91.3% identity in 208 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2205>:










a672.seq




1
ATGAGGAAAA TCCGCACCAA AATCTGCGGC ATCACCACAC CGGAAGACGC



 


51
ACTGTATGCC GCCCACGCCG GCGCAGACGC ATTGGGACTG GTTTTTTACC


 


101
CCCAAAGCCC CCGCGCTGTC GACATCATTA AAGCACAAAA AATCACCGCC


 


151
GCACTGCCGC CGTTTGTCAG CGTTGTCGCC CTTTTCGTCA ACGAAAGCGC


 


201
GCAAAACATC CGCCGCATCC TTGCCGAAGT ACCGATACAC ATCATCCAAT


 


251
TCCACGGCGA CGAAGACGAC GCATTCTGCC GCCAGTTCCA CCGCCCCTAT


 


301
ATCAAGGCCA TTCGTGTTCA GACGGCATCA GACATCCGAA ACGCCGCCGA


 


351
CCGCTTCCCC GACGCTCAGG CACTGCTGTT CGATGCCTAC CATCCTTCGG


 


401
AATACGGCGG CACCGGACAC CGCTTCGACT GGACGCTGTT GGCGGAATAT


 


451
TCGGGCAAAC CGTGGGTGCT TGCCGGCGGG CTGACCCCTG AAAACGTCGA


 


501
CGAAGCCATC CGCATCACCG GAGCGGAAGC GGTCGATGTA TCCGGCGGCG


 


551
TGGAAGCGTC TAAAGGCAAA AAAGACCCAG CCAAAGTTGC CGCCTTTATC


 


601
GCAACCGCCA ACCGCCTATC CCGTTAA






This corresponds to the amino acid sequence <SEQ ID 2206; ORF 672.a>:










a672.pep




1
MRKIRTKICG ITTPEDALYA AHAGADALGL VFYPQSPRAV DIIKAQKITA



 


51
ALPPFVSVVA LFVNESAQNI RRILAEVPIH IIQFHGDEDD AFCRQFHRPY


 


101
IKAIRVQTAS DIRNAADRFP DAQALLFDAY HPSEYGGTGH RFDWTLLAEY


 


151
SGKPWVLAGG LTPENVDEAI RITGAEAVDV SGGVEASKGK KDPAKVAAFI


 


201
ATANRLSR*






m672/a672 91.8% identity in 208 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2207>:










g673.seq




1
ATGGATATTG AAACCTTCCT TGCAGGGGAA CGCGCCGCCG GCGGATACCG



 


51
TTGCGGCTTC GTGGCGATTG TCGGTCGTCC GAACGTGGGC AAATCAACGC


 


101
TGATGAACCA TCTCATCGGT CAGAAAATCA GTATTACCAG CAAAAAGGCG


 


151
CAGACGACGC GCAACCGCGT AACGGGGATT TATACCGACG ATACCGCGCA


 


201
GTTCGTGTTT GTCGATACGC CGGGCTTTCA AACCGACCAC CGCAACGCGC


 


251
TCAACGACAG GCTGAATCAA AATGTTACCG AGGCGCTCGG CGGTGTGGAT


 


301
GTGGTGGTTT TCGTCGTGGA GGCGATGCGC CTTACCGATG CCGACCGCGT


 


351
CGTGTTGAAA CAACTGCCCA AGCACACGCC GGTCATTTTA GTGATCAACA


 


401
AAATCGACAA GGACAAGGCG AAAGACCGTT ACGCGCTGGA GGCGTTTGTT


 


451
GCCCAAGTGC GCGCCGAATT TGAATTTGCG GCGGCGGAGG CGGTCAGTGC


 


501
GAAACACGGT TTGCGGATTG CCAACCTGTT GGAGCTGCTC AAGCCGTATC


 


551
TGCCCGAAAG CGTACCGATG TATCCCGAAG ACATGGTTAC GGACAAATCG


 


601
GCGCGTTTTT TGGCGATGGA AATCGTGCGT GAAAAACTCT TCCGCTATTT


 


651
GGGCGAGGAG CTGCCTTATG CGATGAACGT CGAAGTGGAG CAGTTTGAAG


 


701
AGGGAGACGG TTTGAACCGC ATCTACatcg cCGTTTTGGT CGACAAAGAA


 


751
AGCCAAAAGG CGATTTTGAT CGGTAAAGGC GGGGAGCGTT TGAAAAAAAT


 


801
TTCCACCGAA GCGCGGCTGG ATATGGAAAA ACTGTTTGAT AACAAAGTAT


 


851
TTTTGAAGGT CTGGGTCAAA GTCAAATCCG GTTGGGCAGA CGACATTCGC


 


901
TTCCTGCGCG AGCTGGGTTT GTAG






This corresponds to the amino acid sequence <SEQ ID 2208; ORF 673.ng>:










g673.pep




1
MDIETFLAGE RAAGGYRCGF VAIVGRPNVG KSTLMNHLIG QKISITSKKA



 


51
QTTRNRVTGI YTDDTAQFVF VDTPGFQTDH RNALNDRLNQ NVTEALGGVD


 


101
VVVFVVEAMR LTDADRVVLK QLPKHTPVIL VINKIDKDKA KDRYALEAFV


 


151
AQVRAEFEFA AAEAVSAKHG LRIANLLELL KPYLPESVPM YPEDMVTDKS


 


201
ARFLAMEIVR EKLFRYLGEE LPYAMNVEVE QFEEGDGLNR IYIAVLVDKE


 


251
SQKAILIGKG GERLKKISTE ARLDMEKLFD NKVFLKVWVK VKSGWADDIR


 


301
FLRELGL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2209>:










m673.seq




1
ATGGATATTG AAACCTTCCT TGCAGGGGAA CGCGCCGCCG GCGGATACCG



 


51
TTGCGGCTTC GTAGCGATTG TCGGCCGTCC GAACGTGGGC AAATCAACGC


 


101
TGATGAACCA TCTCATCGGT CAGAAAATCA GTATTACCAG CAAAAAGGCG


 


151
CAGACGACGC GCAACCGCGT AACGGGGATT TATACCGACG ATACCGCGCA


 


201
GTTCGTGTTT GTCGATACGC CCGGCTTTCA AACCGACCAC CGCAACGCGC


 


251
TCAACGACAG GCTGAATCAA AATGTTACCG AGGCGCTCGG CGGCGTGGAT


 


301
GTGGTGGTTT TCGTCGTGGA GGCGATGCGC TTTACCGATG CCGACCGCGT


 


351
CGTGTTGAAA CAACTGCCCA AGCACACGCC GGTCATTTTA GTGGTCAACA


 


401
AAATCGACAA GGACAAGGCG AAAGACCGTT ACGCGCTGGA GGCGTTTGTT


 


451
GCCCAAGTGC GCGCCGAATT TGAATTTGCG GCGGCGGAGG CGGTCAGCGC


 


501
GAAACACGGA TTGCGGATTG CCAACCTGTT GGAGCTGATT AAGCCGTATC


 


551
TGCCCGAAAG CGTGCCGATG TATCCCGAAG ATATGGTTAC GGACAAATCG


 


601
GCGCGTTTTT TGGCGATGGA AATCGTGCGT GAAAAATTGT TCCGCTATTT


 


651
GGGCGAGGAA TTGCCTTATG CGATGAACGT CGAAGTGGAG CAGTTTGAAG


 


701
AGGAAGACGG TTTGAACCGC ATCTATATCG CCGTTTTGGT CGATAAGGAA


 


751
AGCCAAAAGG CAATTTTAAT CGGTAAAGGC GGAGAACGTT TGAAGAAAAT


 


801
TTCCACCGAA GCGCGGTTGG ATATGGAAAA ACTGTTTGAT ACCAAAGTAT


 


851
TTTTGAAGGT CTGGGTCAAA GTCAAATCCG GTTGGGCGGA CGACATCCGC


 


901
TTCCTGCGCG AGCTGGGTTT GTAG






This corresponds to the amino acid sequence <SEQ ID 2210; ORF 673>:










m673.pep




1
MDIETFLAGE RAAGGYRCGF VAIVGRPNVG KSTLMNHLIG QKISITSKKA



 


51
QTTRNRVTGI YTDDTAQFVF VDTPGFQTDH RNALNDRLNQ NVTEALGGVD


 


101
VVVFVVEAMR FTDADRVVLK QLPKHTPVIL VVNKIDKDKA KDRYALEAFV


 


151
AQVRAEFEFA AAEAVSAKHG LRIANLLELI KPYLPESVPM YPEDMVTDKS


 


201
ARFLAMEIVR EKLFRYLGEE LPYAMNVEVE QFEEEDGLNR IYIAVLVDKE


 


251
SQKAILIGKG GERLKKISTE ARLDMEKLFD TKVFLKVWVK VKSGWADDIR


 


301
FLRELGL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m673/g673 98.4% identity in 307 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2211>:










a673.seq




1
ATGGATATTG AAACCTTCCT TGCAGGGGAA CGCGCCGCCG ACGGATACCG



 


51
TTGCGGCTTC GTAGCGATTG TCGGCCGTCC GAACGTGGGC AAATCAACGC


 


101
TGATGAATCA TCTCATCGGT CAGAAAATCA GTATTACCAG CAAAAAGGCG


 


151
CAGACGACGC GCAACCGCGT AACGGGGATT TATACCGACG ATACCGCGCA


 


201
GTTTGTGTTT GTCGATACGC CCGGTTTTCA AACCGACCAC CGCAACGCGC


 


251
TCAACGACCG TTTGAATCAA AACGTTACCG AGGCACTCGG CGGCGTGGAT


 


301
GTGGTGGTTT TCGTCGTGGA AGCGATGCGT TTTACCGATG CCGACCGCGT


 


351
CGTGTTGAAA CAACTGCCCA AGCACACGCC GGTCATTTTA GTGGTCAACA


 


401
AAATCGATAA GGACAAGGCG AAAGACCGTT ACGCGCTGGA GGCGTTTGTT


 


451
GCCCAGGTGC GCGCCGAATT TGAATTTGCG GCGGCGGAGG CGGTCAGCGC


 


501
GAAACACGGA TTGCGGATTG CCAACCTGTT GGAGCTGATT AAGCCGTATC


 


551
TGCCCGAAAG CGTGCCGATG TATCCCGAAG ATATGGTTAC GGACAAATCG


 


601
GCGCGTTTTT TAGCGATGGA AATCGTGCGT GAAAAATTGT TCCGCTATTT


 


651
GGGCGAGGAA TTGCCTTATG CGATGAACGT CGAAGTGGAG CAGTTTGAAG


 


701
AGGAAGACGG TTTGAACCGC ATCTATATCG CCGTTTTGGT CGATAAGGAA


 


751
AGCCAAAAGG CGATTTTAAT CGGCAAAGGC GGGGAGCGTT TGAAGAAAAT


 


801
TTCCACCGAA GCGCGGTTGG ATATGGAAAA ACTGTTTGAT ACCAAAGTAT


 


851
TTTTGAAGGT CTGGGTCAAA GTCAAATCCG GTTGGGCGGA CGACATCCGC


 


901
TTCCTGCGCG AGCTGGGTTT GTAG






This corresponds to the amino acid sequence <SEQ ID 2212. ORF 673.a>:










a673.pep




1
MDIETFLAGE RAADGYRCGF VAIVGRPNVG KSTLMNHLIG QKISITSKKA



 


51
QTTRNRVTGI YTDDTAQFVF VDTPGFQTDH RNALNDRLNQ NVTEALGGVD


 


101
VVVFVVEAMR FTDADRVVLK QLPKHTPVIL VVNKIDKDKA KDRYALEAFV


 


151
AQVRAEFEFA AAEAVSAKHG LRIANLLELI KPYLPESVPM YPEDMVTDKS


 


201
ARFLAMEIVR EKLFRYLGEE LPYAMNVEVE QFEEEDGLNR IYIAVLVDKE


 


251
SQKAILIGKG GERLKKISTE ARLDMEKLFD TKVFLKVWVK VKSGWADDIR


 


301
FLRELGL*






m673/a673 99.7% identity in 307 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2213>:










g674.seq




1
ATGAAAACAG CCCGCCGCCG TTCCCGCGAG CTTGCCGTAC AAGCCGTTTA


 


51
CCAATCCCTT ATCAACCGCA CCGCCGCGCC CGAAATTGCT AAAAACATCC


 


101
GCGAAATGTC CGACTTTGCC AAAGCGGACG AAGAATTGTT CAACAAACTC


 


151
TTCTTCGGCA CACAAACCAA TGCAGCGGAC TACATCCAAA AAATCCGCCC


 


201
GCTGCTCGAC AGGGACGAAA AAGACCTCAA CCCCATCGAA CGCGCCGTTT


 


251
TGCTGACCGC CTGCCACGAG CTTTCCGCTA TGCCCGAAAC GCCCTACCCC


 


301
GTCATTATCA ACGAAGCCAT CGAAGTTACC AAAACCTTCG GCGGCACGGA


 


351
CGGGCACAAA TTCGTCAACG GCATCCTCGA CAAACTCGCC GCCCAAATCC


 


401
GCCCAGACGA GCCCAAACGC CGTTGA






This corresponds to the amino acid sequence <SEQ ID 2214; ORF 674.ng>:










g674.pep




1
MKTARRRSRE LAVQAVYQSL INRTAAPEIA KNIREMSDFA KADEELFNKL


 


51
FFGTQTNAAD YIQKIRPLLD RDEKDLNPIE RAVLLTACHE LSAMPETPYP


 


101
VIINEAIEVT KTFGGTDGHK FVNGILDKLA AQIRPDEPKR R*






The following partial DNA sequence was identified in N. meningitides <SEQ ID 2215>:










m674.seq




1
ATGAAAACAG CCCGCCGCCG TTCCCGCGAG CTTGCCGTAC AAGCCGTTTA


 


51
CCAATCCCTT ATCAACCGCA CCGCCGCGCC CGAAATTGCT AAAAACATCC


 


101
GCGAAATGTC CGACTTTGCC AAGGCAGACG AAGAATTGTT CAACAAACTT


 


151
TTCTTCGGCA CGCAAACCAA TGCGGCAGAG TATATCCGAC AAATCCGCCC


 


201
GCTACTTGAC AGGGACGAAA AAGACCTCAA CCCCATCGAA CGCGCCGTTT


 


251
TGCTGACCGC CTGCCACGAG CTGTCCGCCA TGCCCGAAAC GCCCTACCCC


 


301
GTCATTATCA ACGAAGCCAT CGAAGTTACC AAAACCTTCG GCGGCACGGA


 


351
CGGGCACAAA TTCGTCAACG GCATCCTCGA CAAACTCGCC GCCCAAATCC


 


401
GCCCCGACGA GCCCAAACGC CGTTGA






This corresponds to the amino acid sequence <SEQ ID 2216; ORF 674>:










m674.pep




1
MKTARRRSRE LAVQAVYQSL INRTAAPEIA KNIREMSDFA KADEELFNKL


 


51
FFGTQTNAAE YIRQIRPLLD RDEKDLNPIE RAVLLTACHE LSAMPETPYP


 


101
VIINEAIEVT KTFGGTDGHK FVNGILDKLA AQIRPDEPKR R*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m674/g674 97.9% identity in 141 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2217>:










a674.seq




1
ATGAAAACAG CCCGCCGCCG TTCCCGCGAG CTTGCCGTAC AAGCCGTTTA


 


51
CCAATCCCTT ATCAACCGCA CCGCCGCGCC CGAGATTGCT AAAAACATCC


 


101
GCGAAATGCC CGACTTTGCC AAGGCAGACG AAGAATTGTT CAACAAACTT


 


151
TTCTTCGGCA CGCAAACCAA TGCGGCAGAG TACATCCGAC AAATCCGCCC


 


201
CCTGCTCGAC CGCGACGAAA AAGACCTCAA CCCCATCGAA CGCGCCGTCC


 


251
TGCTGACCGC CTGCCACGAG CTGTCCGCCA TGCCCGAAAC GCCCTACCCC


 


301
GTCATCATCA ACGAAGCCAT CGAAGTAACC AAAACCTTCG GCGGCACGGA


 


351
CGGGCACAAA TTCGTCAACG GCATCCTCGA CAAACTCGCC GCCCAAATCC


 


401
GTCCCGACGA GCCCAAACGC CGTTGA






This corresponds to the amino acid sequence <SEQ ID 2218; ORF 674.a>:










a674.pep




1
MKTARRRSRE LAVQAVYQSL INRTAAPEIA KNIREMPDFA KADEELFNKL


 


51
FFGTQTNAAE YIRQIRPLLD RDEKDLNPIE RAVLLTACHE LSAMPETPYP


 


101
VIINEAIEVT KTFGGTDGHK FVNGILDKLA AQIRPDEPKR R*






m674/a674 99.3% identity in 141 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2219>:










g675.seq




1
ATGAACACCA TCGCCCCcaa cctcgacgGC AAACACCTCC GCATCGGCAT


 


51
CGTACAGGCA CGCTTCACCA ACGAAATCGG CAGCCAAATG CTCAAAGTCT


 


101
GCTGCCGCAC CCTCCAAGAA TTGGGCGTAG CAGACGAAAa catcaccgtc


 


151
gCCACCGTAC CCGGCGCGCT TGAAATCCCC ATCGCGCTGA TGAACTTTGC


 


201
CTCTTCCGAA AAATTTGACG CACTGATTGC CATCGGCGTC GTCATCCGTG


 


251
GCGAAACCTA CCATTTCGAG CTGGTTGCCA ACGAATCCGG CGCAGGGATC


 


301
GGCCGCGTCG CACTCGACTA CAACATCCCG ATTGCCAACG CCGTCCTGAC


 


351
CACCGAAAAC GACGCGCAGG CAATTGAACG GATTGGAGAA AAAGCCTCGG


 


401
ATGCCGCCAA AGTCGCCGTA GAATGCGCCA ACCTCGTCAA CCTTCTGCTC


 


451
GAAGAACAGT TTGAAGACGA AGAATAA






This corresponds to the amino acid sequence <SEQ ID 2220; ORF 675.ng>:










g675.pep




1
MNTIAPNLDG KHLRIGIVQA RFTNEIGSQM LKVCCRTLQE LGVADENITV


 


51
ATVPGALEIP IALMNFASSE KFDALIAIGV VIRGETYHFE LVANESGAGI


 


101
GRVALDYNIP IANAVLTTEN DAQAIERIGE KASDAAKVAV ECANLVNLLL


 


151
EEQFEDEE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2221>:










m675.seq




1
ATGAACACCA TCGCCCCCAA CCTCGACGGC AAACACCTCC GCATCGGCAT


 


51
CGTACAGGCA CGCTTCACCA ACGAAATCGG CAGCGAAATG CTCAAAGTCT


 


101
GCTGCCGCAC CCTCCAAGAA TTGGGCGTGG CAGACGAAAA CATTACCGTC


 


151
GCCACCGTAC CCGGCGCGCT TGAAATCCCC ATCGCGCTGA TGAACTTTGC


 


201
CTCTTCCGAA AAGTTTGACG CACTGATTGC CATCGGCGTC GTCATCCGTG


 


251
GCGAAACCTA CCATTTCGAG CTGGTTTCCA ACGAATCCGG AGCAGGCGTC


 


301
AGCCGCGTCG CACTCGACTA CAATATCCCG ATTGCCAATG CCGTCCTAAC


 


351
CACCGAAAAC GACGCGCAGG CAATCGAACG GATTGAAGAA AAAGCCTCGG


 


401
ATGCCGCCAA AGTCGCCGTC GAATGCGCCA ACCTCGTCAA CCTGCTGCTC


 


451
GAAGAACAGT TTGAAGACGA AGAATAA






This corresponds to the amino acid sequence <SEQ ID 2222; ORF 675>:










m675.pep




1
MNTIAPNLDG KHLRIGIVQA RFTNEIGSEM LKVCCRTLQE LGVADENITV


 


51
ATVPGALEIP IALMNFASSE KFDALIAIGV VIRGETYHFE LVSNESGAGV


 


101
SRVALDYNIP IANAVLTTEN DAQAIERIEE KASDAAKVAV ECANLVNLLL


 


151
EEQFEDEE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m675/g675 96.8% identity in 158 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2223>:










a675.seq




1
ATGAACACCA TCGCCCCCAA CCTCGACGGC AAACACCTCC GCATCGGCAT


 


51
CGTACAGGCA CGCTTCACCA ACGAAATCGG CAGCGAAATG CTCAAAGTCT


 


101
GCTGCCGCAC CCTCCAAGAA TTGGGCGTGG CAGACGAAAA CATTACCGTC


 


151
GCCACCGTAC CCGGCGCGCT TGAAATCCCC ATCGCGCTGA TGAACTTTGC


 


201
CTCTTCTGAA AAATTTGACG CACTGATTGC CATCGGCGTC GTTATCCGTG


 


251
GCGAAACCTA CCATTTCGAG CTGGTTTCCA ACGAATCCGG AGCAGGGGTC


 


301
AGCCGCGTCG CACTCGACTA CAACATCCCG ATTGCCAATG CCGTCCTGAC


 


351
CACGGAAAAC GACGCACAGG CAATCGAACG GATTGAAGAA AAAGCCTCGG


 


401
ATGCCGCCAA AGTCGCCGTA GAATGCGCCA ACCTCGTCAA CCTCCTGCTC


 


451
GAAGAACAGT TTGAAGACGA AGAATAA






This corresponds to the amino acid sequence <SEQ ID 2224; ORF 675.a>:










a675.pep




1
MNTIAPNLDG KHLRIGIVQA RFTNEIGSEM LKVCCRTLQE LGVADENITV


 


51
ATVPGALEIP IALMNFASSE KFDALIAIGV VIRGETYHFE LVSNESGAGV


 


101
SRVALDYNIP IANAVLTTEN DAQAIERIEE KASDAAKVAV ECANLVNLLL


 


151
EEQFEDEE*






m675/a675 100.0% identity in 158 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2225>:










g677.seq




1
ATGCCGCAGA TTTTGGTGCG GATTTTCCTC ATTCGGTATT CCTTTATTtg


 


51
ggAAACGGTG CGCTTGTGCC GTTTCAGACG GCATTCCCGA TCAGTCGATT


 


101
TTGATGTATT CGACAGAAAG GATTTCAATT TCCTCACGGC CTTCCGGCGT


 


151
GTTCAAAACC ACTTCGTCGC CTTCGCGCGC TTTAATCAGG CAACGCGCCA


 


201
ACGGCGAAAT CCAAGAAATT TTGTTTTGCG CGGTATCGAT TTCATCGACG


 


251
CCGACGATTT TGACGGTTTG CTCGCGCCCG TCGCCGCGCA ACAGACCGAC


 


301
GGTCGCGCCG AAAAATACTT GGTCGGTCGC TTCGCGCAAT TCGGGATCGA


 


351
CGACGACGGC AGCCTCCAAA CGTTTGGTCA GGAAACGGAT GCGGCGGTCG


 


401
ATTTCGCGCA TACGGCGTTT GCCGTAAAGA TAGTCGCCGT TTTCGCTGCG


 


451
GTCGCCGTTG CCTGCCGCCC AGTTGACGAT TTGGACGATT TCGGGGCGTT


 


501
CTTTATTGAC CAGTTGATAA AGCTCGTCTT TCAATGCCTG CCATCCGGCG


 


551
GGCGTAATGT AGTTTTTGGT TTCGGTACTC ATATTGTGTG CGGATGA






This corresponds to the amino acid sequence <SEQ ID 2226; ORF 677.ng>:










g677.pep




1
MPQILVRIFL IRYSFIWETV RLCRFRRHSR SVDFDVFDRK DFNFLTAFRR


 


51
VQNHFVAFAR FNQATRQRRN PRNFVLRGID FIDADDFDGL LAPVAAQQTD


 


101
GRAEKYLVGR FAQFGIDDDG SLQTFGQETD AAVDFAHTAF AVKIVAVFAA


 


151
VAVACRPVDD LDDFGAFFID QLIKLVFQCL PSGGRNVVFG FGTHIVCG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2227>:










m677.seq




1
ATGCCGCAGA TTTTGGTGCG GATTTTCCTC ATTCGGTATT CCTTTATTTG


 


51
GGAAACGGCG CGCTTTTGCC GTTTCAGACG GCATTCCCGA TCAGTCGATT


 


101
TTGATGTATT CGACAGAAAG GATTTCAATT TCCTCACGCC CTTCCGGCGT


 


151
GTTCAAAACC ACTTCGTCGC CTTCGCGCGC TTTAATCAGA CAACGAGCCA


 


201
GCGGCGAAAT CCAAGAAATT TTGTTTTGCG CGGTATCGAT TTCATCGATG


 


251
CCGACGATTT TGACGGTTTG CTCGCGCCCG TCGTCGCGCA ACAGTCCGAC


 


301
CGTCGCGCCG AAAAACACTT GGTCGGTCGC TTCGCGCAAT TCGGGATCGA


 


351
CGACGACGGC AGCCTCCAAA CGTTTGGTCA GGAAACGGAT GCGGCGGTCG


 


401
ATTTCGCGCA TACGGCGTTT GCCGTAAAGA TAGTCGCCGT TTTCGCTGCG


 


451
GTCGCCGTTG CCTGCCGCCC AGTTGACGAT TTGGACGATT TCGGGGCGTT


 


501
CTTTGTTGAC CAGTTGATAA AGCTCGTCTT TCAATGCCTG CCATCCGGCG


 


551
GGCGTAATGT AGTTTTTGGT TTCGGTACTC ATATTGTGTG CGGATGA






This corresponds to the amino acid sequence <SEQ ID 2228; ORF 677>:










m677.pep




1
MPQILVRIFL IRYSFIWETA RFCRFRRHSR SVDFDVFDRK DFNFLTPFRR


 


51
VQNHFVAFAR FNQTTSQRRN PRNFVLRGID FIDADDFDGL LAPVVAQQSD


 


101
RRAEKHLVGR FAQFGIDDDG SLQTFGQETD AAVDFAHTAF AVKIVAVFAA


 


151
VAVACRPVDD LDDFGAFFVD QLIKLVFQCL PSGGRNVVFG FGTHIVCG*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m677/g677 94.9% identity in 198 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2229>:










a677.seq




1
ATGCCGCAGA TTTTGGTGCG GATTTTCCTC ATTCGGTATT CCTTTATTTG


 


51
GGAAACGGCG CGTTTGTGCC GTTTCAGACG GCATTCCCGA TCAGTCGATT


 


101
TTGATGTATT CGACAGAAAG GATTTCAATT TCCTCACGCC CTTCCGGCGT


 


151
GTTTAAAACC ACTTCGTCGC CTTCACGCGC TTTAATCAGA CAACGAGCCA


 


201
GCGGCGAAAT CCAAGAAATT TTGTTTTGCG CGGTATCGAT TTCATCGATG


 


251
CCGACGATTT TGACGGTTTG CTCGCGCCCG TCGCCGCGCA ACAGACCGAC


 


301
GGTCGCGCCG AAAAACACTT GGTCGGTCGC TTCGCGCAAT TCGGGATCAA


 


351
CGACGACGGC GGCTTCCAAA CGCTTGGTCA GGAAACGGAT GCGGCGGTCG


 


401
ATTTCGCGCA TACGGCGTTT GCCGTAAAGG TAGTCGCCGT TTTCGCTGCG


 


451
GTCGCCGTTG CCTGCCGCCC AGTTGACGAT TTGGACGATT TCGGGGCGTT


 


501
CTTTATTAAC CAGTTGATAA AGCTCGTCTT TCAATGCCTG CCATCCGGCG


 


551
GGCGTAATGT AGTTTTTGGT TTCGGTACTC ATATTGTGTG CGGATGA






This corresponds to the amino acid sequence <SEQ ID 2230; ORF 677.a>:










a677.pep




1
MPQILVRIFL IRYSFIWETA RLCRFRRHSR SVDFDVFDRK DFNFLTPFRR


 


51
V*NHFVAFTR FNQTTSQRRN PRNFVLRGID FIDADDFDGL LAPVAAQQTD


 


101
GRAEKHLVGR FAQFGINDDG GFQTLGQETD AAVDFAHTAF AVKVVAVFAA


 


151
VAVACRPVDD LDDFGAFFIN QLIKLVFQCL PSGGRNVVFG FGTHIVCG*






m677/a677 93.4% identity in 198 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2231>:










g678.seq




1
ATGAATAGCC TCCCCATTGC CGACCTCCTC GCCTccgCCG TCATCGCCGC


 


51
CTGCATCGTC ATTTCCACGA TGCGCGGCGT GATTGCGGAA GCAggttcGA


 


101
TGGTgGCATG ggtggTTTcc tTCTTTTttg ccAAACTCTt tGCCGCACcc


 


151
ttcgccgACC TCGCCTTTGc ctCGTTCCAA ccccgccTGT TTGCAttggc


 


201
tCTGTCATTC ATTTCCCTGT TCGTCATTGC CTGTCTGATC CAGAAAATGC


 


251
TCCGTTCGCT GCTGACCGGC GCAGTTTCGG CGGTCGGTCT GGGCTTTGCC


 


301
AACCGCATTT TGGGCGGTGT ATTCGGTGCA TTGAAAGGCG TTTTGATTGT


 


351
TACCCTGCTG ATCATGCTTG CTTCAAAAAC CGACCTGCCC GATACCGAAG


 


401
AATGGCAACA GTCCTATACC GTACCGTTTT TCGTATCGCT TTCCGAAGCG


 


451
GTGTTAAACC atacggaCAA CGCacccgaa tCCCtcgacg acgactaa






This corresponds to the amino acid sequence <SEQ ID 2232; ORF 678.ng>:










g678.pep




1
MNSLPIADLL ASAVIAACIV ISTMRGVIAE AGSMVAWVVS FFFAKLFAAP


 


51
FADLAFASFQ PRLFALALSF ISLFVIACLI QKMLRSLLTG AVSAVGLGFA


 


101
NRILGGVFGA LKGVLIVTLL IMLASKTDLP DTEEWQQSYT VPFFVSLSEA


 


151
VLNHTDNAPE SLDDD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2233>:










m678.seq




1
ATGAATAGCC TCCCCATTGC CGACCTCCTC GTCTCCGCCG TCATCGCCGC


 


51
CTGCATCGTG CTATCCGCGA TGCGCGGCGT GATTGCGGAG GCAGGCTCAA


 


101
TGGCGGCATG GGTGGTTTCC TTCTTTTTCG CCAAACTCTT TGCCGCCTCC


 


151
TTCGCCGACC TCGCCTTTGC CTCGTTCCAA CCCCGCCTGT TTGCATTGGC


 


201
TCTGTCGTTC ATTTCCCTGT TCGTCATTGC CTGTCTGATC CAGAAAATGC


 


251
TCCGTTCGCT GCTGACCAGC GCAGTTTCGG CGGTCGGTTT GGGCTTTGCC


 


301
AACCGCATTT TGGGCGGCGT ATTCGGTGCA TTGAAAGGCG TTTTGATTGT


 


351
TACCCTGCTG GTCATGCTTG CTTCAAAAAC CGACCTGCCC GATACCGAAG


 


401
AATGGCGGCA ATCTTACACA CTGCCGTTTT TCGTATCGCT TTCCGAAGCC


 


451
GTGTTGAACC ATAGCGGCGG CACGGCGGAA ACTCCGGAAG ACGATTGA






This corresponds to the amino acid sequence <SEQ ID 2234; ORF 678>:










m678.pep




1
MNSLPIADLL VSAVIAACIV LSAMRGVIAE AGSMAAWVVS FFFAKLFAAS


 


51
FADLAFASFQ PRLFALALSF ISLFVIACLI QKMLRSLLTS AVSAVGLGFA


 


101
NRILGGVFGA LKGVLIVTLL VMLASKTDLP DTEEWRQSYT LPFFVSLSEA


 


151
VLNHSGGTAE TPEDD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m678/g678 89.7% identity in 165 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2235>:










a678.seq




1
ATGAATAACC TCCCCGTTGC CGACCTCCTC GTCTCCGCCA TCATCGCCGC


 


51
CTGCATCGTG CTATCCGCGA TGCGCGGCGT GATTGCGGAG GCTGGCTCAA


 


101
TGGCGGCATG GGTGGTTGCC TTTTTTTTCG CCAAACTCTT TGCCGCACCC


 


151
TTCGCCGACA TCGCCTTTGC ATCGTTCCAA CCCCGCCTGT TTGCATTGGC


 


201
TCTGTCGTTC ATTTCCCTAT TCGTCATTGC CTGTCTGATC CAGAAAATAC


 


251
TCCGCTCGCT GCTGACCGGG GCAGTTTCGG CGGTCGGTTT GGGCTTTGCC


 


301
AACCGCATTT TGGGCGGCGT ATTCGGTGCA TTGAAAGGCA TTTTGATTAT


 


351
TACCCTGCTG GTCATGCTCG CTTCAAAAAC CGACCTGCCC GATACCGAAG


 


401
AATGGCGGCA ATCTTACACA CTGCCGTTTT TCGTATCGCT TTCCGAAGCC


 


451
GTGTTGAACC ATAGCGGCGG CACGGCGGAA ACTCCGGAAG ACGATTGA






This corresponds to the amino acid sequence <SEQ ID 2236; ORF 678.a>:










a678.pep




1
MNNLPVADLL VSAIIAACIV LSAMRGVIAE AGSMAAWVVA FFFAKLFAAP


 


51
FADIAFASFQ PRLFALALSF ISLFVIACLI QKILRSLLTG AVSAVGLGFA


 


101
NRILGGVFGA LKGILIITLL VMLASKTDLP DTEEWRQSYT LPFFVSLSEA


 


151
VLNHSGGTAE TPEDD*






m678/a678 93.9% identity in 165 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2237>:










g680.seq




1
ATGACGAAGG GCAGTTCGGC GATGTCCAGC CCACGCGCGG CGATATCGGT


 


51
GGCGACGAGG ACGCGCAGGC TGCCGTCTTT GAAGGCGTTG AGTGTTTCGA


 


101
GCCTGCTTTG TTGGGAACGG TCGCCGTGTA TCGCCTGTGC GGACAGGTTG


 


151
CGGCGCACCA GTTCGCGCGT TACGCGGTCG ACGCTTTGTT TGGTtttgCA


 


201
AAAGACGATA ACTTGGTTCA TATGCAGATC GACAATCAGC CGTTCGAGCA


 


251
GGTTGCGCTT TTGGAAGGTA TCGACGGCGA TGATGTgttg ttcGACGTTG


 


301
GCGTTGGTGG TGTTTTGGGC GGCAACCTCG ACGGTTTCGG GCGCGTTCAT


 


351
GAAGTCTTGC GCCAGTTTGC GTATCGGTGC GGAGAAGGTG GCGGAAAAGA


 


401
GCAGGGTTTG GCGTTGGCGG GGCAGCATCT GCATGATTTT GCGGATGTCG


 


451
TCGATAAACC CCATATCCAA CATGCGGTCT GCTTCGTCCA GAACGACGAT


 


501
TTCGGCTTTG TTTAAACTGA TGTTTTTCTG TTTCACATGG TCGAGCAGCC


 


551
GTCCGACGGT GGCGACGACT ATTTCGCAGC CGGCACGCAG GTCGGCGGTT


 


601
TGTTTGTCCA TGTTGACACC GCCGAAGAGG ACGGTATGCC GCAGCGGCAG


 


651
GTTTTTAATg tag






This corresponds to the amino acid sequence <SEQ ID 2238; ORF 680.ng>:










g680.pep




1
MTKGSSAMSS PRAAISVATR TRRLPSLKAL SVSSLLCWER SPCIACADRL


 


51
RRTSSRVTRS TLCLVLQKTI TWFICRSTIS RSSRLRFWKV STAMMCCSTL


 


101
ALVVFWAATS TVSGAFMKSC ASLRIGAEKV AEKSRVWRWR GSICMILRMS


 


151
SINPISNMRS ASSRTTISAL FKLMFFCFTW SSSRPTVATT ISQPARRSAV


 


201
CLSMLTPPKR TVCRSGRFLM *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2239>:










m680.seq




1
ATGACGAAGG GCAGTTCGGC AATGTCCAGC CCGCGCGCGG CGATGTCGGT


 


51
GGCGACGAGG ACGCGCAGGT TGCCGTCTTT GAAGGCGTTG AGTGTTTCGA


 


101
GCCGGCTTTG TTGGGAACGG TCGCCGTGTA TCGCCTGTGC GGACAGGTTG


 


151
CGGCGCACCA GTTCGCGCGT TACGCGGTCG ACGCTTTGTT TGGTTTTGCA


 


201
GAACACGATG ACCTGGTTCA TATGCAAATC GACAATCAGC CGTTCGAGCA


 


251
GGTTGCGCTT CTGAATGGTA TCGACGGCGA TGATGTGCTG CTCGACGTTG


 


301
GCGTTGGTGG TGTTTTGCGC GGCGACTTCG ACGGTTTCGG GCGCGTTCAT


 


351
GAAGTCTTGC GCCAGTTTGC GTATCGGGGC GGAGAAGGTG GCGGAAAAGA


 


401
GCAGGGTTTG GCGTTGGCGG GGCAGCATCT GCATGATTTT GCGGATGTCG


 


451
TCGATAAAAC CCATATCCAG CATACGGTCG GCTTCGTCCA AAACGACGAT


 


501
TTCGACTTTG TTCAAATGGA TGTTTTTCTG TTTCACGTGG TCGAGCAGCC


 


551
GTCCGACGGT GGCGACGACG ATTTCGCAGC CGGCACGCAG GTCGGCGGTC


 


601
TGTTTGTCCA TATTCATACC GCCGAACAAG ACGGTGTGGC GCAGCGGCAG


 


651
GTTTTTGATG TAG






This corresponds to the amino acid sequence <SEQ ID 2240; ORF 680>:










m680.pep




1
MTKGSSAMSS PRAAMSVATR TRRLPSLKAL SVSSRLCWER SPCIACADRL


 


51
RRTSSRVTRS TLCLVLQNTM TWFICKSTIS RSSRLRF*MV STAMMCCSTL


 


101
ALVVFCAATS TVSGAFMKSC ASLRIGAEKV AEKSRVWRWR GSICMILRMS


 


151
SIKPISSIRS ASSKTTISTL FKWMFFCFTW SSSRPTVATT ISQPARRSAV


 


201
CLSIFIPPNK TVWRSGRFLM *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m680/g680 90.9% identity in 220 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2241>:










a680.seq




1
ATGACGAAGG GCAGTTCGGC AATATCCAGC CCCCGCGCGG CGATATCGGT


 


51
GGCGACGAGG ACGCGCAGGT TGCCGTCTTT GAAGGCGTTG AGTGTTTCGA


 


101
GCCGGCTTTG TTGGGAACGG TCGCCGTGTA TCGCCTGTGC GGACAGGTTG


 


151
CGGCGCACCA GTTCGCGCGT TACGCGGTCG ACGCTTTGTT TGGTTTTGCA


 


201
GAACACGATG ACCTGGTTCA TATGCAAATC GACAATCAGC CGTTCGAGCA


 


251
GGTTGCGCTT CTGAATGGTA TCGACGGCGA TGATGTGCTG CTCGACGTTG


 


301
GCGTTGGTGG TGTCTTGCGC GGCGACTTCG ACGGTTTCGG GCGCGTTCAT


 


351
GAAGTCTTGC GCCAGTTTGC GTATCGGGGC GGAGAAGGTG GCGGAAAAGA


 


401
GCAGGGTTTG GCGTTGGCGG GGCAGCATCT GCATGATTTT GCGGATGTCG


 


451
TCGATAAAAC CCATATCCAG CATACGGTCG GCTTCGTCCA AAACGACGAT


 


501
TTCGACTTTG TTCAAATGGA TGTTTTTCTG TTTCACGTGG TCGAGCAGCC


 


551
GTCCGACGGT GGCGACGACG ATTTCGCAGC CGGCACGCAG GTCGGCGGTC


 


601
TGTTTGTCCA TATTCATACC GCCGAACAAG ACGGTGTGGC GCAGCGGCAG


 


651
GTTTTTGATG TAG






This corresponds to the amino acid sequence <SEQ ID 2242; ORF 680.a>:










a680.pep




1
MTKGSSAISS PRAAISVATR TRRLPSLKAL SVSSRLCWER SPCIACADRL


 


51
RRTSSRVTRS TLCLVLQNTM TWFICKSTIS RSSRLRF*MV STAMMCCSTL


 


101
ALVVSCAATS TVSGAFMKSC ASLRIGAEKV AEKSRVWRWR GSICMILRMS


 


151
SIKPISSIRS ASSKTTISTL FKWMFFCFTW SSSRPTVATT ISQPARRSAV


 


201
CLSIFIPPNK TVWRSGRFLM *






m680/a680 98.6% identity in 220 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2243>:










g681.seq




1
ATGACGACGC CGATGGCAAT CAGTGCGTCA AATTTTTCGG AAGAGGCAAA


 


51
GTTCATCAGC GCGATGGGGA TTTCAAGCGC GCCGGGTACG GTGGcgacgg


 


101
tgatgtTTTC GTCTGCTACG CCCAATTCTT GGAGGGTGCG GCAGCAGACT


 


151
TTGAGCATTT GGCTGCCGAT TTCGTTGGTG AAGCGTGCCT GTACGATGCC


 


201
GATGCGGAGG TGTTTGCcgt cgaggttgGG GGCGATGGTG TTCATTGGGT


 


251
GTCCTTTGGT ATTCGGGGTT TCGGAATGCC GTCTGAAGGT TTCAGTCTTG


 


301
CGGCTGCCAG TCGGCAACGG TTTGGAATGT GCCGTCTTCG GCAAGCTCCC


 


351
ACGCGCTGCC TTCGGGTTGG GAAAGCAGTG CGGCGGTTTC AGGGTTGGTT


 


401
TTGGTGATGT CGGCGAGGCT GACGATGCTG AAGTTGTCGG GGTCGTCGGT


 


451
GTATTCGTCG GTTTCGTCGC CGCTGAAGAA ACGCCAGCCG CTGTCGTTTT


 


501
CAAAAACGGG GGCTTCGCGG TAAAGGAAGC CGACGGGCCG GTTTTGTTTG


 


551
GCGACGGTGT TGGTGGCGAT GCAGCGGTCG AGTGCCGAGG AAAGTGCTTG


 


601
TGCAAATGCG TTCATTGCGG GAATACGTTG GGGGGGGGGA AACTTGCGGA


 


651
TTTTACCACG ATTCCCGCGT TGTCGGCAGA CGGCGGCGGT TTGGTGGTAC


 


701
AATGTGCGCC GTTTGCAGCC TTAAGGTGTT TCTGTATTTT TGGAGTATGG


 


751
AAACGCATTC GGGCTGTTTT TTGCGGAAGA CGGTAA






This corresponds to the amino acid sequence <SEQ ID 2244; ORF 681>:










g681.pep




1
MTTPMAISAS NFSEEAKFIS AMGISSAPGT VATVMFSSAT PNSWRVRQQT


 


51
LSIWLPISLV KRACTMPMRR CLPSRLGAMV FIGCPLVFGV SECRLKVSVL


 


101
RLPVGNGLEC AVFGKLPRAA FGLGKQCGGF RVGFGDVGEA DDAEVVGVVG


 


151
VFVGFVAAEE TPAAVVFKNG GFAVKEADGP VLFGDGVGGD AAVECRGKCL


 


201
CKCVHCGNTL GGGKLADFTT IPALSADGGG LVVQCAPFAA LRCFCIFGVW


 


251
KRIRAVFCGR R*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2245>:










m681.seq




1
ATGACGACGC CGATGGCAAT CAGTGCGTCA AACTTTTCGG AAGAGGCAAA


 


51
GTTCATCAGC GCGATGGGGA TTTCAAGCGC GCCGGGTACG GTGGCGACGG


 


101
TAATGTTTTC GTCTGCCACG CCCAATTCTT GGAGGGTGCG GCAGCAGACT


 


151
TTGAGCATTT CGCTGCCGAT TTCGTTGGTG AAGCGTGCCT GTACGATGCC


 


201
GATGCGGAGG TGTTTGCCGT CGAGGTTGGG GGCGATGGTG TTCATTGGGT


 


251
GTCCTTTGGT ATTCGGAGTT TCGGAATGCC GTCTGAAGGT TTCAGTCTTG


 


301
CGGCTGCCAG TCGGCGACGG TTTGGAATGT GCCGTCTTCG GCAAGCTCCC


 


351
ATGCGCTGCC TTCGGGTTGG GAGAGCAGTG CGGCGGTTTC AGGGTTGGTT


 


401
TTGGCGATGT CGGCGAGGCT GACGATGCTG AAGTTGTCCG GATCGTCGGT


 


451
GTATTCGTCG GTCTCGTCGC CGCTGAAGAA ACGCCAGCCG CTGTCGTTTT


 


501
CAAAAACGGG GGCTTCGCGG TAGAGGAAGC CGACGGGCCG GTTTTGTTTG


 


551
GCGACGGTGT TGGTGGCGAT ACAGCGGTCG AGTGCCGAGG AAAGTGCTTG


 


601
TGCAAATGCG TTCATTACGG GAATACGTTG GGGG.AAAAC TTACGGATTT


 


651
TACCACGATT CGTGCGTTGT CGGCAGACGG CGGCGGTTTG GTGGTACAAT


 


701
GTGCGCCGTT TGCAGCCTTA AGGTGTTTCT GTATTTTTGG AGTATGGAAA


 


751
CGCATTCGGG CTGTTTTTTG CGGAAGACGG TAA






This corresponds to the amino acid sequence <SEQ ID 2246; ORF 681>:










m681.pep




1
MTTPMAISAS NFSEEAKFIS AMGISSAPGT VATVMFSSAT PNSWRVRQQT


 


51
LSISLPISLV KRACTMPMRR CLPSRLGAMV FIGCPLVFGV SECRLKVSVL


 


101
RLPVGDGLEC AVFGKLPCAA FGLGEQCGGF RVGFGDVGEA DDAEVVRIVG


 


151
VFVGLVAAEE TPAAVVFKNG GFAVEEADGP VLFGDGVGGD TAVECRGKCL


 


201
CKCVHYGNTL GXKLTDFTTI RALSADGGGL VVQCAPFAAL RCFCIFGVWK


 


251
RIRAVFCGRR *






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 681 shows 94.6% identity over a 261 aa overlap with a predicted ORF (ORF681.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2247>:










a681.seq




1
ATAACGACGC CGATGGCAAT CAGTGCGTCA AATTTTTCAG AAGAGGCAAA


 


51
GTTCATCAGC GCGATGGGGA TTTCAAGCGC GCCGGGTACG GTGGCGACGG


 


101
TAATGTTTTC GTCTGCCACG CCCAATTCTT GGAGGGTGCG GCAGCAGACT


 


151
TTGAGCATTT CGCTGCCGAT TTCGTTGGTG AAGCGTGCCT GTACGATGCC


 


201
GATGCGGAGG TGTTTGCCGT CGAGGTTGGG GGCGATGGTG TTCATTGAGT


 


251
GTCCTTTGGT ATTCGGAGGT TTCGGAATGC CGTCTGAAGG GTCAGTCCTT


 


301
AGGTTGCCAG TCGGCGACGG TTTGGAATGT GCCGTCTTCT GCCAATTCCC


 


351
ACGCGCTGCC TTCAGGTTGG GAGAGCAGTG CGGCGGTTTC AGGGTTGGTT


 


401
TTGGTGATAT CGGCGAGGCT GACGATGCTG AAGTTGTCCG GGTCGTCGGT


 


451
GTATTCGTCG GTCTCGTCGC CGCTGAAGAA ACGCCAGCCG CTGTCGTTTT


 


501
CAAAAACGGG GGCTTCGCGG TAGAGGAAGC CGACGGGCTG GTTTTGTTTG


 


551
GCGACGGTGT TGGTGGCGAT GCAGCGGTCG AGTGCCGAGG AAAGTGCTTG


 


601
TGCAAATGCG TTCATTGCGG GAATACGTT. GGGGGAAAAC TTGCGGATTT


 


651
TACCACGATT CTTGCGTTGT CGGCAGACGG CGGCGGTTTG GTGGTACAAT


 


701
GTGCGCCGTT TGCAGCCTTA AGGTGTTTCT GTATTTTTGG AGTATGGAAA


 


751
CGCATTCGGG CTGTTTTTTG CGGAAGACGG TAA






This corresponds to the amino acid sequence <SEQ ID 2248; ORF 681.a>:










a681.pep




1
ITTPMAISAS NFSEEAKFIS AMGISSAPGT VATVMFSSAT PNSWRVRQQT


 


51
LSISLPISLV KRACTMPMRR CLPSRLGAMV FIECPLVFGG FGMPSEGSVL


 


101
RLPVGDGLEC AVFCQFPRAA FRLGEQCGGF RVGFGDIGEA DDAEVVRVVG


 


151
VFVGLVAAEE TPAAVVFKNG GFAVEEADGL VLFGDGVGGD AAVECRGKCL


 


201
CKCVHCGNTX GGKLADFTTI LALSADGGGL VVQCAPFAAL RCFCIFGVWK


 


251
RIRAVFCGRR *






m681/a681 90.8% identity in 260 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2249>:










g682.seq




1
ATGCGCGATT TCGCCGTATG GGTGCCTTAC GGGGAACGGC GGAAAAATTG


 


51
GGACATAAGG TATTGCCTCC CGCACCTTAT TCGCCTGAGC CCAACCCGAT


 


101
TGAGAAAGTG TGGGCGAATA TTAAGCGGTA TCTGCGAACC GTTTTGTCTG


 


151
ATTACGCCCG ATTTGACGAT GCACTACTGT CCTATTTTGA TTTTAATTGA


 


201
CTATATTTGT GTGAATGATG AAATAAAAAT GCCGTCTGAA CCCGATTGGA


 


251
TTCAGACGGC ATTTTGTATG GCAGGATTTA TTCGCTTTCC AACTGACCGA


 


301
CCTATTTTGA CAAGGCAGTC AGGCGTTGTT CGGATTTCGC CACGAACGGG


 


351
TTTTCGGTAT CCCACGCGTA GCCTGCCAAA ATCGAAGAAA GCATACGGCT


 


401
GA






This corresponds to the amino acid sequence <SEQ ID 2250; ORF 682>:










g682.pep




1
MRDFAVWVPY GERRKNWDIR YCLPHLIRLS PTRLRKCGRI LSGICEPFCL


 


51
ITPDLTMHYC PILILIDYIC VNDEIKMPSE PDWIQTAFCM AGFIRFPTDR


 


101
PILTRQSGVV RISPRTGFRY PTRSLPKSKK AYG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2251>:










m682.seq




1
ATGCGTGATT TCACCGTATG GGTGTCTTAC GGGAAATGGC GGAAAAATTG


 


51
GGACATAAGG TATTGCCTCT TGCACCTTAT TCACCTGAGC TCAACCCGAT


 


101
TGAGAAAGTG TGGGCGAATA TTAAGCGGTA TCTGCGAACC GTTTTGTCTG


 


151
ATTACGCCCG ATTTGACGAT GCACTACTGT CCTATTTTGA TTTTAATTGA


 


201
CTAT...... ......GAAA TGGCAATGCC GTCTGAACCC GATTGGATTC


 


251
AGACGGCATT TTGTATGGCG TACGGATTTA TTCGGTTTCC AACTGACCGA


 


301
CCCATTCGGA CAAGGCAGTC AGGCGTTGTT CGGATTTCGC CACGAACGGG


 


351
TTTTCGGTAT CCCACGCGTA GCCTGCCAAA ATCGAAGAAA GCATACGGCT


 


401
GA






This corresponds to the amino acid sequence <SEQ ID 2252; ORF 682>:










m682.pep




1
MRDFTVWVSY GKWRKNWDIR YCLLHLIHLS STRLRKCGRI LSGICEPFCL


 


51
ITPDLTMHYC PILILIDY.. ..EMAMPSEP DWIQTAFCMA YGFIRFPTDR


 


101
PIRTRQSGVV RISPRTGFRY PTRSLPKSKK AYG*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 682 shows 88.1% identity over a 134 aa overlap with a predicted ORF (ORF682.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2253>:










a682.seq




1
ATGCGCGATT TTACCGTATG GGTGTCTTAC GGGAAATGGC GGAAAAATTG


 


51
GGACATAAGG TATTGCCTCT TGCACCTTAT TCACCTGAGC TCAACCCGAT


 


101
TGAGAAAGTG TGGGCGAATA TTAAGCGGTA TCTGCGAACC GTTTTGTCTG


 


151
ATTACGCCCG ATTTGACGAT GCACTACTGT CCTATTTTGA TTTTAATTGA


 


201
ATAT...... .......... .......... .......... ..........


 


251
.......... .......... ......TATA TTCGGTTTCC AACTGACCGA


 


301
CCCATTCTGA CAAGGCCGAC AGGCGTTGTT CGGATTTCGC CACGAACGGG


 


351
TTTTCGGTAT CCCACGCGTA GCCTGCCAAA ATCGAAGAAA GCATACGGCT


 


401
GA






This corresponds to the amino acid sequence <SEQ ID 2254; ORF 682.a>:










a682.pep




1
MRDFTVWVSY GKWRKNWDIR YCLLHLIHLS STRLRKCGRI LSGICEPFCL


 


51
ITPDLTMHYC PILILIEY.. .......... .......... ..YIRFPTDR


 


101
PILTRPTGVV RISPRTGFRY PTRSLPKSKK AYG*






m682/a682 80.6% identity in 129 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2255>










g683.seq




1
ATGATTAAGG AAACCCTAAT GCGCCCAATC TTCCTATCTT TCGTTTTACT


 


51
CCCTATTTTG ATAACCGCCT GCAGCACACC GGACAAGTCT GCCCGATGGG


 


101
AAAATATCGG CACAATCTCA AACGGCAATA TTCATACATA TATTAATAAA


 


151
GACAGTGTGA GAAAAAACGG AAATCTGATG ATTTTCCAAG ATAAAAAAGT


 


201
TGTTACCAAT CTGAAACAAG AACGTTTTGC CAACACCCCC GCATACAAGA


 


251
CTGCCATTGC CGAGTGGGAA ATCCACTGCA ACAACAAAAC ATACCGCTTA


 


301
AGTTCGCTAC AGTTATTTGA TACAAAAAAC ACGGAAATTT CCACACAAAA


 


351
CTACACAGCC TCTTCCCTCC GCCCGATGAG CATCCTGTCC GGGACATTAA


 


401
CTGAAAAACA ATATGAAACC GTATGCGGGA AAAAACTCTG A






This corresponds to the amino acid sequence <SEQ ID 2256; ORF 683>:










g683.pep




1
MIKETLMRPI FLSFVLLPIL ITACSTPDKS ARWENIGTIS NGNIHTYINK


 


51
DSVRKNGNLM IFQDKKVVTN LKQERFANTP AYKTAIAEWE IHCNNKTYRL


 


101
SSLQLFDTKN TEISTQNYTA SSLRPMSILS GTLTEKQYET VCGKKL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2257>:










m683.seq..




1
ATGATTAAGG AAACCCTAAT GCGCCCAATC TTCCTATCTT TCGTTTTATT


 


51
CCCTATTTTG ATAACCGCCT GCAGCACACC GGACAAGTCT GCCCGATGGG


 


101
AAAATATCGG CACAATCTCA AACGGCAATA TTCATACATA TATCAATAAA


 


151
GACAGCGTGA GAAAAAACGG AAATCTGATG ATTTTCCAAG ATAAAAAAGT


 


201
TGTTACCAAT CTAAAACAAG AACGTTTTGC CAACACCCCC GCATACAAGA


 


251
CTGCCATTGC CGAGTGGGAA ATCCACTGCA ACAACAAAAC ATACCGCTTA


 


301
AGTTCGCTAC AGTTGTTTGA TACAAAAAAC ACGGAAATTT CCACACAAAA


 


351
CTACACAGCC TCTTCCCTCC GCCCGATGAG CATCCTGTCC GGGACATTAA


 


401
CCGAAAAACA ATATGAAACC GTATGCGGAA AAAAACTCTG A






This corresponds to the amino acid sequence <SEQ ID 2258; ORF 683>:










m683.pep..




1
MIKETLMRPI FLSFVLFPIL ITACSTPDKS ARWENIGTIS NGNIHTYINK



 


51
DSVRKNGNLM IFQDKKVVTN LKQERFANTP AYKTAIAEWE IHCNNKTYRL


 


101
SSLQLFDTKN TEISTQNYTA SSLRPMSILS GTLTEKQYET VCGKKL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 683 shows 99.3% identity over a 146 aa overlap with a predicted ORF (ORF 683) from N. gonorrhoeae: 

m683/g683 99.3% identity in 146 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2259>










a683.seq




1
ATGATTAAGG AAACCCTAAT GCGCCCAATC TTCCTATCTT TCGTTTTATT



 


51
CCCTATTTTG ATAACCGCCT GCAGCACACC GGACAAGTCT GCCCGATGGG


 


101
AAAATATCGG CACAATCTCA AACGGCAATA TTCATACATA TATCAATAAA


 


151
GACAGCGTGA GAAAAAACGG AAATCTGATG ATTTTCCNAG ATAAAAAAGT


 


201
TGTTACCAAT CTAAAACAAG AACGTTTTGC CNACACCCCC GCATACAAGA


 


251
CTGCCATTGC CGAGTGGGAA ATCCACTGCA ACAACAAAAC ATACCGCTTA


 


301
AGTTCGCTAC AATTGTTTGA TACAAAAAAC ACGGAAATTT CCACACAAAA


 


351
NTACACAGCC TCTTCCCTCC GCCCGATGAG CATCCTGTCC GGGACATTAA


 


401
CCGAAAAACA ATATGAAACC GTATGCGGAA AAAAACTCTG A






This corresponds to the amino acid sequence <SEQ ID 2260; ORF 683.a>:










a683.pep




1
MIKETLMRPI FLSFVLFPIL ITACSTPDKS ARWENIGTIS NGNIHTYINK



 


51
DSVRKNGNLM IFXDKKVVTN LKQERFAXTP AYKTAIAEWE IHCNNKTYRL


 


101
SSLQLFDTKN TEISTQXYTA SSLRPMSILS GTLTEKQYET VCGKKL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 683 shows 97.9% identity over a 146 aa overlap with a predicted ORF (ORF 683) from N. meningitidis: 

m683/a683 97.9% identity in 146 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2261>










g684.seq




1
ATGCGCCTTT TCCCCATCGC CGCCGCCCTG ACGCTTGCCG CCTGCGGTAC



 


51
TGTGCAAAGC ACACAATATT TCGTGTTGCC CGACAGCCGC TACATCCGTC


 


101
CTGCAACGCA AGGCGGCGAA ACCGCCGTCG AAGTCCGTCT TGCCGAACCG


 


151
CTCAAACGCG GCGGACTGGT CTATCAAACC GACCCCTACC GCATCAACAC


 


201
CGCACAAAAC CATGTTTGGG CAGACACCTT GGACGATATG CTCGAAGCGG


 


251
CGTTGAGCAA TGCATTCAAC CGTTTGGACA GCACACGCAC CTTTGTTCCT


 


301
GCCTCACGCA GCGGCAGTAC CGACAAATGG ACGGTCTATA TCGACGCATT


 


351
CCAAGGCAGC TACACGGGCA AAACCCTCAT CAGCGGCTAC GCCGTCCTAC


 


401
CCGACGGTAC GAACAGACCC TTCCATATCG AAACCGAACA GCAGGGTGAC


 


451
GGCTACGCCG CCATGACCGC CGCACTCGAA CAGGGACTGA AACAGGCGGC


 


501
GCAACAGATG GTCGAGTAA






This corresponds to the amino acid sequence <SEQ ID 2262; ORF 684>:










g684.pep




1
MRLFPIAAAL TLAACGTVQS TQYFVLPDSR YIRPATQGGE TAVEVRLAEP



 


51
LKRGGLVYQT DPYRINTAQN HVWADTLDDM LEAALSNAFN RLDSTRTFVP


 


101
ASRSGSTDKW TVYIDAFQGS YTGKTLISGY AVLPDGTNRP FHIETEQQGD


 


151
GYAAMTAALE QGLKQAAQQM VE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2263>:










m684.seq




1
ATGCGCCTTT TCCCGATTGC CGCCGCCCTG TCGCTTGCCG CCTGCGGTAC



 


51
TGTGCAAAGC ACACAATATT TCGTGTTGCC CGACAGCCGC TACATCCGTC


 


101
CTGCAACGCA AGGCGGCGAA ACTGCCGTCG AAGTCCGTCT TGCCGAACCG


 


151
CTCAAACGCG GCGGACTGGT CTATCAAACC GACCCCTACC GCCTCAACAC


 


201
CGCACAAAAC CACGTCTGGG CAGACACCTT GGACGATATG CTCGAAGCGG


 


251
CGTTGAGCAA TGCATTCAAC CGTTTGGACA GCACACGCAT CTTTGTTCCT


 


301
GCCTCACGCA GCGGCAGTAC CGAAAAATGG ACGGTCTATA TCGACGCATT


 


351
CCAAGGCAGC TACACGGGCA AAACCCTCAT CAGCGGCTAC GCCGTCCTAC


 


401
CCGACGGTAC GAACAGACCC TTCCATATCG AAACCGAACA GCAGGGTGAC


 


451
GGCTACGCCG CGATGACCGC CGCACTCGAA CAGGGACTGA AACAGGCGGC


 


501
GCAACAGATG GTCGAGTAA






This corresponds to the amino acid sequence <SEQ ID 2264; ORF 684>:










m684.pep




1
MRLFPIAAAL SLAACGTVQS TQYFVLPDSR YIRPATQGGE TAVEVRLAEP



 


51
LKRGGLVYQT DPYRLNTAQN HVWADTLDDM LEAALSNAFN RLDSTRIFVP


 


101
ASRSGSTEKW TVYIDAFQGS YTGKTLISGY AVLPDGTNRP FHIETEQQGD


 


151
GYAAMTAALE QGLKQAAQQM VE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 684 shows 97.7% identity over a 172 aa overlap with a predicted ORF (ORF 684) from N. gonorrhoeae: 

m684/g684 97.7% identity in 172 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2265>










a684.seq




1
ATGCGCCTCT TCCCGATTGC CGCCGCCCTG ACGCTTGCCG CCTGCGGTAC



 


51
TGTGCAAAGC ACACAATATT TCGTGTTGCC CGACAGCCGC TACATCCGTC


 


101
CTGCAACGCA AGGCGGCGAA ACTGCCGTCG AAGTCCGTCT TGCCGAACCG


 


151
CTCAAACGCG GCGGACTGGT CTATCAAACC GACCCCTACC GCCTCAACAC


 


201
CGCACAAAAC CACGTCTGGG CAGACACCTT GGACGATATG CTCGAAGCGG


 


251
CGTTGAGCAA TGCATTCAAC CGTTTGGACA GCACACGCAT CTTTGTTCCT


 


301
GCCTCACGCA GCGGCAGTAC CGAAAAATGG ACGGTCTATA TCGACGCATT


 


351
CCAAGGCAGC TACACGGGCA AAACCCTCAT CAGCGGCTAC GCCGTCCTAC


 


401
CCGACGGTAC GAACAGACCC TTCCATATCG AAACCGAACA GCAGGGTGAC


 


451
GGCTACGCCG CCATGACCGC CGCACTCGAA CAGGGACTGA AACAGGCGGC


 


501
GCAACAGATG GTCGAGTAA






This corresponds to the amino acid sequence <SEQ ID 2266; ORF 684.a>:










a684.pep




1
MRLFPIAAAL TLAACGTVQS TQYFVLPDSR YIRPATQGGE TAVEVRLAEP



 


51
LKRGGLVYQT DPYRLNTAQN HVWADTLDDM LEAALSNAFN RLDSTRIFVP


 


101
ASRSGSTEKW TVYIDAFQGS YTGKTLISGY AVLPDGTNRP FHIETEQQGD


 


151
GYAAMTAALE QGLKQAAQQM VE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 684 shows 99.4% identity over a 172 aa overlap with a predicted ORF (ORF 684) from N. meningitidis 

m684/a684 99.4% identity in 172 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2267>










g685.seq




1
TTGTTTTGCC GTATCGGGAA TTTTGCGTTT TGCGGCGTGG TTTCTGCAGG



 


51
TTGTTTGCTT AATAATAAAC ATTCTTATTC GTATGCAAAG GAACCGCACA


 


101
CCGTGAAACC GCGTTTTTAT TGGGCAGcct GCGCCGTCCT GCCGGCCGCC


 


151
TGTTCGCCCG AACCTGCCGC CGAAAAAACT GTATccgCCG CATCCCAAGC


 


201
CGCATCCACA CCTGTCGCCA CGCTGACCGT GCCGACCGCG CGGGGCGATG


 


251
CCGTTGTGCC GAAGAATCCC GAACgcgtcg ccgtgtAcga CtggGCGGCG


 


301
TtggaTACGC TGACCGAGCC GGGCGTGAAT GTGGGCGCAA CCACCGCGCC


 


351
GGTGCGCGTG GACTATTTGC AGCCTGCATT TGACAAGGCG GCAACGGTGG


 


401
GGACGCTGTT TGAGCCCGAT TGCGAATCCC TGCACCGCCA CAATCCGCAG


 


451
TTTGTCATTA CCGGCGGGCC GGGTGCGGAA GCGTATGAAC AGTTGGCGAA


 


501
AAACGCGACC ACCATAGATT TGACGGTGGA CAACGGCAAT ATCCGCACCA


 


551
GCGGCGAGAA GCAGATGGAG ACCCTGTCGC GGATTTTCGG TAAGGAAGCG


 


601
CGCGTGGCGG AATTGAATGC GCAGATTGAC GCGCTGTTCG CCCAAAAGCG


 


651
CGAAGCCGCC AAAGGCAAAG GACGCGGGCT GGTGCTGTCG GTTACAGGCA


 


701
ACAAGGTGTC CGCCTTCGGC ACGCAATCGC GGTTGGCAAG TTGGATACAC


 


751
GGCGACATCG GCCTGCCGCC CGTGGACGAA TCTTTACGCA ACGAAGGGCA


 


801
CGGGCAGCCC GTTTCCTTCG AATACATCAA AGAGAAAAAC CCCGGCTGGA


 


851
TTTTCATCAT CGACCGCACC GCCGCCATCG GGCAGGAAGG GCCGGCTGCC


 


901
GTGGAAGTGT TGGATAACGC GCTGGTATGC GGCACGAACG CTTGGAAGCG


 


951
CAAGCAAATC ATCGTCATGC CTGCCGCGAA CTACATTGTC GCGGGCGGCG


 


1001
CGCGGCAGTT GATACAGGCG GCGGAACAGT TGAAGGCGGC GTTTGAAAAG


 


1051
GCAGAACCCG TTGCGGCGCA GTAG






This corresponds to the amino acid sequence <SEQ ID 2268; ORF 685>:










g685.pep




1
LFCRIGNFAF CGVVSAGCLL NNKHSYSYAK EPHTVKPRFY WAACAVLPAA



 


51
CSPEPAAEKT VSAASQAAST PVATLTVPTA RGDAVVPKNP ERVAVYDWAA


 


101
LDTLTEPGVN VGATTAPVRV DYLQPAFDKA ATVGTLFEPD CESLHRHNPQ


 


151
FVITGGPGAE AYEQLAKNAT TIDLTVDNGN IRTSGEKQME TLSRIFGKEA


 


201
RVAELNAQID ALFAQKREAA KGKGRGLVLS VTGNKVSAFG TQSRLASWIH


 


251
GDIGLPPVDE SLRNEGHGQP VSFEYIKEKN PGWIFIIDRT AAIGQEGPAA


 


301
VEVLDNALVC GTNAWKRKQI IVMPAANYIV AGGARQLIQA AEQLKAAFEK


 


351
AEPVAAQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2269>:










m685.seq




1
TTGTTTTGCC GTATCGGGAA TTTTGCGTTT TGCGGCGTGG TTTCTGCAGG



 


51
TTGTTTGCTT AATAATAAAC ATTCTTATTC GTATGCAAAG GAACCGCACA


 


101
CCGTGAAACC GCGTTTTTAT TGGGCAGCCT GCGCCGTCCT GCTGACCGCC


 


151
TGTTCGCCCG AACCTGCCGC CGAAAAAACT GTATCCGCCG CATCCGCATC


 


201
TGCCGCCACG CTGACCGTGC CGACCGCGCG GGGCGATGCC GTTGTGCCGA


 


251
AGAATCCCGA ACGCGTCGCC GTGTACGACT GGGCGGCGTT GGATACGCTG


 


301
ACCGAATTGG GCGTGAATGT GGGCGCAACC ACCGCGCCGG TGCGCGTGGA


 


351
TTATTTGCAG CCTGCATTTG ACAAGGCGGC AACGGTGGGG ACGCTGTTCG


 


401
AGCCCGATTA CGAAGCCCTG CACCGCTACA ATCCTCAGCT TGTCATTACC


 


451
GGCGGGCCGG GCGCGGAAGC GTATGAACAG TTAGCGAAAA ACGCGACCAC


 


501
CATAGATCTG ACGGTGGACA ACGGCAATAT CCGCACCAGC GGCGAAAAGC


 


551
AGATGGAGAC CTTGGCGCGG ATTTTCGGCA AGGAAGCGCG CGCGGCGGAA


 


601
TTGAAGGCGC AGATTGACGC GCTGTTCGCC CAAACGCGCG AAGCCGCCAA


 


651
AGGCAAAGGA CGCGGGCTGG TGCTGTCGGT TACGGGCAAC AAGGTGTCCG


 


701
CCTTCGGCAC GCAGTCGCGG TTGGCAAGTT GGATACACGG CGACATCGGC


 


751
CTACCGCCTG TAGACGAATC TTTACGCAAC GAGGGGCACG GGCAGCCTGT


 


801
TTCCTTCGAA TACATCAAAG AGAAAAACCC CGATTGGATT TTCATCATCG


 


851
ACCGTACCGC CGCCATCGGG CAGGAAGGGC CGGCGGCTGT CGAAGTATTG


 


901
GATAACGCGC TGGTACGCGG CACGAACGCT TGGAAGCGCA AGCAAATCAT


 


951
CGTCATGCCT GCCGCGAACT ACATTGTCGC GGGCGGCGCG CGGCAGTTGA


 


1001
TTCAGGCGGC GGAGCAGTTG AAGGCGGCGT TTAAAAAGGC AGAACCCGTT


 


1051
GCGGCGGGGA AAAAGTAG






This corresponds to the amino acid sequence <SEQ ID 2270; ORF 685>:










m685.pep




1
LFCRIGNFAF CGVVSAGCLL NNKHSYSYAK EPHTVKPRFY WAACAVLLTA



 


51
CSPEPAAEKT VSAASASAAT LTVPTARGDA VVPKNPERVA VYDWAALDTL


 


101
TELGVNVGAT TAPVRVDYLQ PAFDKAATVG TLFEPDYEAL HRYNPQLVIT


 


151
GGPGAEAYEQ LAKNATTIDL TVDNGNIRTS GEKQMETLAR IFGKEARAAE


 


201
LKAQIDALFA QTREAAKGKG RGLVLSVTGN KVSAFGTQSR LASWIHGDIG


 


251
LPPVDESLRN EGHGQPVSFE YIKEKNPDWI FIIDRTAAIG QEGPAAVEVL


 


301
DNALVRGTNA WKRKQIIVMP AANYIVAGGA RQLIQAAEQL KAAFKKAEPV


 


351
AAGKK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 685 shows 94.4% identity over a 356 aa overlap with a predicted ORF (ORF 685) from N. gonorrhoeae: 

m685/g685 94.4% identity in 356 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2271>










a685.seq




1
TTGTTTTGCC GTATCGGGAA TTTTGCGTTT TGCGGCGTGG TTTCTGCAGG



 


51
TTGTTTGCTT AATAATAAAC ATTCTTATTC GTATGCAAAG GAACCGCACA


 


101
CCGTGAAACC GCGTTTTTAT TGGGCAGCCT GCGCCGTCCT GCTGACCGCC


 


151
TGTTCGCCCG AACCTGCCGC CGAAAAAACT GTATCCGCCG CATCCGCATC


 


201
TGCCGCCACA CTGACCGTGC CGACCGCGCG GGGCGATGCC GTTGTGCCGA


 


251
AGAATCCCGA ACGCGTCGCC GTGTACGACT GGGCGGCGTT GGATACGCTG


 


301
ACCGAATTGG GTGTGAATGT GGGCGCAACC ACCGCGCCGG TGCGCGTGGA


 


351
TTATTTGCAG CCTGCATTTG ACAAGGCGGC AACGGTGGGG ACGCTGTTCG


 


401
AGCCCGATTA CGAAGCCCTG CACCGCTACA ATCCTCAGCT TGTCATTACC


 


451
GGCGGGCCGG GCGCGGAAGC GTATGAACAG TTGGCGAAAA ACGCGACCAC


 


501
CATAGATCTG ACGGTGGACA ACGGCAATAT CCGCACCAGC GGCGAAAAGC


 


551
AGATGGAGAC CTTGGCGCGG ATTTTCGGCA AGGAAGCGCG CGCGGCGGAA


 


601
TTGAAGGCGC AGATTGACGC GCTGTTCGCC CAAACGCGCG AAGCCGCCAA


 


651
AGGCAAAGGA CGCGGGCTGG TGCTGTCGGT TACGGGCAAC AAGGTGTCCG


 


701
CCTTCGGCAC GCAGTCGCGG TTGGCAAGTT GGATACACGG CGACATCGGC


 


751
CTACCGCCTG TAGACGAATC TTTACGCAAC GAGGGGCACG GGCAGCCTGT


 


801
TTCCTTCGAA TACATCAAAG AGAAAAACCC CGATTGGATT TTCATCATCG


 


851
ACCGTACCGC CGCCATCGGG CAGGAAGGGC CGGCGGCTGT CGAAGTATTG


 


901
GATAACGCGC TGGTACGCGG CACGAACGCT TGGAAGCGCA AGCAAATCAT


 


951
CGTCATGCCT GCCGCGAACT ACATTGTCGC GGGCGGCTCG CGGCAGTTGA


 


1001
TTCAGGCGGC GGAGCAGTTG AAGGAGGCGT TTGAAAAGGC AGAACCCGTT


 


1051
GCGGCGGGGA AAGAGTAG






This corresponds to the amino acid sequence <SEQ ID 2272; ORF 685.a>:










a685.pep




1
LFCRIGNFAF CGVVSAGCLL NNKHSYSYAK EPHTVKPRFY WAACAVLLTA



 


51
CSPEPAAEKT VSAASASAAT LTVPTARGDA VVPKNPERVA VYDWAALDTL


 


101
TELGVNVGAT TAPVRVDYLQ PAFDKAATVG TLFEPDYEAL HRYNPQLVIT


 


151
GGPGAEAYEQ LAKNATTIDL TVDNGNIRTS GEKQMETLAR IFGKEARAAE


 


201
LKAQIDALFA QTREAAKGKG RGLVLSVTGN KVSAFGTQSR LASWIHGDIG


 


251
LPPVDESLRN EGHGQPVSFE YIKEKNPDWI FIIDRTAAIG QEGPAAVEVL


 


301
DNALVRGTNA WKRKQIIVMP AANYIVAGGS RQLIQAAEQL KEAFEKAEPV


 


351
AAGKE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 685 shows 98.9% identity over a 355 aa overlap with a predicted ORF (ORF 685) from N. meningitidis: 

m685/a685 98.9% identity in 355 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2273>









g686.seq (partial)










1
..AATTTCTCCT GCCGCGCCGA TGATGTTTTT GACGATATCT GCAGTGCCGT



 


51
  TGAAGGCTTC ggcgGCATTG CCCGATCTGT CCAGCTCGGG GCTGTATCGG


 


101
  GTGGCGCGTT TGAATCCGTC GCCTACTCCT TGCGTCAGCA TAGCGCCGGC


 


151
  ATTGTGGAAA CGGTCGGCAA GCCGTTGTCC GGTGCTGCGG TTGTCGGTCA


 


201
  GGTTGAGGCG GATATTTTGG GCAACGCCTT TTATGTCGTA GCTGTATATA


 


251
  TCCCTCGCGC CTTTGGGAGC GGGATAGCCG CCGCCCTGTG GCCCGTCATA


 


301
  GCCGTCGGCG GGATGGTGTT CGTATCCGTC CCAATGGATG CGGTAAAGGC


 


351
  TGAATCCGTC AACGGGACTA CCGGCTTCGT CAGAATCGGA ATGTGA






This corresponds to the amino acid sequence <SEQ ID 2274; ORF 686>:









g686.pep (partial)










1
..NFSCRADDVF DDICSAVEGF GGIARSVQLG AVSGGAFESV AYSLRQHSAG



 


51
  IVETVGKPLS GAAVVGQVEA DILGNAFYVV AVYIPRAFGS GIAAALWPVI


 


101
  AVGGMVFVSV PMDAVKAESV NGTTGFVRIG M*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2275>:










m686.seq..




1
ATGATGTTGA AAAAATTCGT ACTCGGCGGT ATTGCCGCAT TGGTTTTGGC


 


51
GGCCTGCGGC GGTTCGGAAG GCGGCAGCGG AGCGNNNNNN NNNNNNAATT


 


101
TCTCCTGCAG CGCCGATGAT GTTTTTAACG ATATCTGCAG TGCCGTTGAA


 


151
GGCTTCGGCG GCATTGCCCG ATCTGTCCAG CTCGGGGCTG TATCGGGTGG


 


201
CGCGTTTGAA TCCGTCGCCT ACTCCTTGCG TCAGCATACT ACCGGCATTG


 


251
TGGAAACGGT CGGCAAGCCG TTGTCCGGTG CTGCGGTTGT CGGTCAGGTT


 


301
GAGGCGGATA TTTTGGGCAA CGCCTTTTAT GTCGTAGCTG TATATATCCC


 


351
TCGCGCCTTT GGGAGCGGGA TAGCCGCCGC CCTGTGGCCC GTCATAGCCG


 


401
TCGGCGGGAT GGTGTTCGTA TCCGTCCCAA TGGATGCGGT AAAGGCTAAA


 


451
TCCGTCAACG GGACTACCGG CTTCATCAGA ATCGGAATGT GA






This corresponds to the amino acid sequence <SEQ ID 2274; ORF 686>:










m686.pep




1
MMLKKFVLGG IAALVLAACG GSEGGSGAXX XXNFSCSADD VFNDICSAVE


 


51
GFGGIARSVQ LGAVSGGAFE SVAYSLRQHT TGIVETVGKP LSGAAVVGQV


 


101
EADILGNAFY VVAVYIPRAF GSGIAAALWP VIAVGGMVFV SVPMDAVKAK


 


151
SVNGTTGFIR IGM*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 686 shows 95.4% identity over a 131 aa overlap with a predicted ORF (ORF 686) from N. gonorrhoeae 

g686/m686 95.4% identity in 131 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2277>









a686.seq (partial)










1
..AATTTCTCCT GCCGCGCCGA TGATGTTTTT GACGATATCT GCAGTGCCGT



 


51
  TGAAAGCTTC GGCGGCATTG CCCGATCTGT CCAGCTCGGG GCTGTATCGG


 


101
  GTGGCGCGTT TGAATCCGTC GCCTACTCCT TGCGTCAGCA TACTACCGGT


 


151
  ATTGTGGAAA CGGTCGACAA GCCGTTGTCC GGTGCTGCGG TTGTCGGTCA


 


201
  GGTTGAGGCG GATATTTTGG GCAACGCCTT TTATGTCGTA GCTGTATATA


 


251
  TCCCTCGCGC CTTTGGGAGC GGGATAGCCG CCGCCCTGTG GCCCGTCATA


 


301
  GCCGTCGGCG GGATGGTGTT CGTATCCGTC CCAATGGATG CGGTAAAGGC


 


351
  TGAATCCGTC AACGGGACTA CCGGCTTCAT CAGAATCGGA ATGTGA






This corresponds to the amino acid sequence <SEQ ID 2278; ORF 686.a>:









a686.pep (partial)










1
..NFSCRADDVF DDICSAVESF GGIARSVQLG AVSGGAFESV AYSLRQHTTG



 


51
  IVETVDKPLS GAAVVGQVEA DILGNAFYVV AVYIPRAFGS GIAAALWPVI


 


101
  AVGGMVFVSV PMDAVKAESV NGTTGFIRIG M*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 686 shows 96.2% identity over a 131 aa overlap with a predicted ORF (ORF 686) from N. meningitidis: 

m686/a686 96.2% identity in 131 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2279>










g687.seq




1
ATGAAATCCA GACACCTCGC CCTCGCCCTC GGCGTTGCCG CCCTGTTCGC


 


51
CCTTGCCGCG TGCGACAGCA AAGTCCAAAC CAGCGTCCCC GCCGACAGCG


 


101
CGCCTGCCGC TTCGGCAGCC GCCGCCCCGG CAGGACTGGT CGAAGGGCAA


 


151
AACTACACCG TCCTTGCCAA CCCGATTCCC CAACAGCAGG CAGGCAAGGT


 


201
TGAAGTGCTT GAGTTTTTCG GCTATTTTTG TCCGCACTGC GCCCGCCTcg


 


251
AACCTGTTTT GAGCAAACAC GCCAAGTCTT TTAAAGACGA TATGTACCTG


 


301
CGTACCGAAC ACGTCGTCTG GCAGAAAGAA ATGCTGCCGC TGGCACGCct


 


351
cGCCGCCGCC GTCGATATGG CTGCCGCCGA AAGCAAAGAT GTGGCGAACA


 


401
GCCATATTTT CGATGCGATG GTCAACCAAA AAATCAAGCT GCAAGAGCCG


 


451
GAAGTCCTCA AAAAATGGCT GGGCGAACAa ACcgcctTTG ACGGCAAAAA


 


501
AGTCCTTGCC GCCTACGAAT CCCCCGAAAG TCAGGCGCGC GCcggcAAAA


 


551
TGCAGGAGCT GACCGAAACC TTCCAAATCG ACGGTACGCC CACGGTTATC


 


601
GTCGGCGGCA AATATAAAGT CGAATTTGCC GACTGGGAGT CCGGTATGAA


 


651
CACCATCGAC CTTTTGGCGG ACAAAGTACG TGAAGAACAA AAAGCCGCGC


 


701
AGTAG






This corresponds to the amino acid sequence <2280 ID 724; ORF 687>:










g687.pep




1
MKSRHLALAL GVAALFALAA CDSKVQTSVP ADSAPAASAA AAPAGLVEGQ


 


51
NYTVLANPIP QQQAGKVEVL EFFGYFCPHC ARLEPVLSKH AKSFKDDMYL


 


101
RTEHVVWQKE MLPLARLAAA VDMAAAESKD VANSHIFDAM VNQKIKLQEP


 


151
EVLKKWLGEQ TAFDGKKVLA AYESPESQAR AGKMQELTET FQIDGTPTVI


 


201
VGGKYKVEFA DWESGMNTID LLADKVREEQ KAAQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2281>:










m687.seq




1
ATGAAATCCA GACACCTTGC CCTCgGCGTT GCCGCCCTGT TCGCCCTTGC


 


51
CGCGTGCGAC AGCAAAGTCC AAACCAGCGT CCCCGCCGAC AGCGCGCCTG


 


101
CCGCTTCGGC AGCCGCCGCC CCGGCAGGGC TGGTCGAAGG GCAAAACTAT


 


151
ACCGTCCTTG CCAACCCGAT TCCCCAACAG CAGGCAGGCA AAGTCGAAGT


 


201
CCTTGAGTTT TTCGGCTATT TCTGTCCGCA CTGCGCCCAC CTCGAACCTG


 


251
TTTTAAGCAA ACACGCCAAG TCTTTTAAAG ACGATATGTA CCTGCGTACC


 


301
GAACACGTCG TCTGGCAGAA AGAAATGCTG ACGCTGGCAC GCCTCGCCGC


 


351
CGCCGTCGAT ATGGCTGCCG CCGACAGCAA AGATGTGGCG AACAGCCATA


 


401
TTTTCGATGC GATGGTCAAC CAAAAAATCA AGCTGCAAAA TCCGGAAGTC


 


451
CTCAAAAAAT GGCTGGGCGA ACAAACCGCC TTTGACGGCA AAAAAGTCCT


 


501
TGCCGCCTAC GAGTCCCCCG AAAGCCAGGC GCGCGCCGAC AAAATGCAGG


 


551
AGCTGACCGA AACCTTCCAA ATCGACGGTA CGCCCACGGT TATCGTCGGC


 


601
GGTAAATATA AAGTTGAATT TGCCGACTGG GAGTCCGGTA TGAACACCAT


 


651
CGACCTTTTG GCGGACAAAG TACGCGAAGA ACAAAAAGCC GCGCAGTAA






This corresponds to the amino acid sequence <SEQ ID 2282; ORF 687>:










m687.pep




1
MKSRHLALGV AALFALAACD SKVQTSVPAD SAPAASAAAA PAGLVEGQNY


 


51
TVLANPIPQQ QAGKVEVLEF FGYFCPHCAH LEPVLSKHAK SFKDDMYLRT


 


101
EHVVWQKEML TLARLAAAVD MAAADSKDVA NSHIFDAMVN QKIKLQNPEV


 


151
LKKWLGEQTA FDGKKVLAAY ESPESQARAD KMQELTETFQ IDGTPTVIVG


 


201
GKYKVEFADW ESGMNTIDLL ADKVREEQKA AQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 687 shows 97.0% identity over a 234 aa overlap with a predicted ORF (ORF 687) from N. gonorrhoeae: 

m687/g687 97.0% identity in 234 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2283>










a687.seq




1
ATGAAATCCA AACACCTCGC CCTCGGCGTT GCCGCCCTGT TCGCACTTGC


 


51
CGCGTGCGAC AGCAAAGTCC AAACCAGCGT CCCCGCCGAC AGCGCGCCTG


 


101
CCGCTTCGGC AGCCGCCGCC CCGGCAGGGC TGGTCGAAGG GCAAAACTAT


 


151
ACTGTCCTTG CCAACCCGAT TCCCCAACAG CAGGCAGGCA AAGTCGAAGT


 


201
CCTTGAGTTT TTCGGCTATT TCTGTCCGCA CTGCGCCCAC CTCGAACCTG


 


251
TTTTAAGCAA ACACGCCAAG TCTTTTAAAG ACGATATGTA CCTGCGTACC


 


301
GAACACGTCG TCTGGCAGAA AGAAATGCTG ACGCTCGCAC GCCTCGCCGC


 


351
CGCCGTCGAT ATGGCTGCCG CCGACAGCAA AGATGTGGCG AACAGCCATA


 


401
TTTTCGATGC GATGGTCAAC CAAAAAATCA AGCTGCAAGA GCCGGAAGTC


 


451
CTCAAAAAAT GGCTGGGCGA ACAAACCGCC TTTGACGGCA AAAAAGTCCT


 


501
TGCCGCTTAC GAATCTCCCG AAAGCCAGGC GCGCGCCGAC AAAATGCAGG


 


551
AGCTGACCGA AACCTTCCAA ATCGACGGTA CGCCCACGGT TATCGTCGGC


 


601
GGCAAATATA AAGTCGAATT TGCCGACTGG GAGTCCGGTA TGAACACCAT


 


651
CGACCTTTTG GCGGACAAAG TACGCGAAGA ACAAAAAGCC GCGCACTAA






This corresponds to the amino acid sequence <SEQ ID 2284; ORF 687.a>:










a687.pep




1
MKSKHLALGV AALFALAACD SKVQTSVPAD SAPAASAAAA PAGLVEGQNY


 


51
TVLANPIPQQ QAGKVEVLEF FGYFCPHCAH LEPVLSKHAK SFKDDMYLRT


 


101
EHVVWQKEML TLARLAAAVD MAAADSKDVA NSHIFDAMVN QKIKLQEPEV


 


151
LKKWLGEQTA FDGKKVLAAY ESPESQARAD KMQELTETFQ IDGTPTVIVG


 


201
GKYKVEFADW ESGMNTIDLL ADKVREEQKA AH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 687 shows 98.7% identity over a 232 aa overlap with a predicted ORF (ORF 687) from N. meningitidis: 

m687/a687 98.7% identity in 232 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2285>










g688.seq




1
GTGCTACACT AGACATCCCG ATTTGCACAG AAAGGTTCTC CCGTGAACAA


 


51
AACCCTCATC CTCGCCCTTT CCGCCCTGTT CAGCCTGACC GCGTGCAGCG


 


101
TCGAACGCGT CTCGCTGTTT CCCTCCTACA AACTCAAAAT CATCCAAGGC


 


151
AACGAACTCG AACCGCGCGC CGTTGCCGCC CTGCGCCCCG GCATGACCAA


 


201
AGACCAAGTC CTGCTCCTGC TCGGCAGCCC CATACTGCGC GACGCTTTCC


 


251
ATACCGACCG CTGGGACTAT ACCTTCAACA CCTCCCGCAA CGGCATCATC


 


301
AAAGAACGCA GCAACCTGAC CGTCTATTTT GAAAACGGCG TACTCGTCCG


 


351
CACCGAAGGC GACGCCCTCC AAAATGCCGC CGAAGCCCTC CGCGCGAAAC


 


401
AAAACGCAGA CAAACAATAA






This corresponds to the amino acid sequence <SEQ ID 2286; ORF 688>:










g688.pep




1
VLH*TSRFAQ KGSPVNKTLI LALSALFSLT ACSVERVSLF PSYKLKIIQG


 


51
NELEPRAVAA LRPGMTKDQV LLLLGSPILR DAFHTDRWDY TFNTSRNGII


 


101
KERSNLTVYF ENGVLVRTEG DALQNAAEAL RAKQNADKQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2287>:










m688.seq




1
GTGTTACACT ACCCATCCCG ATTTGCACAG AAAGGCATTT CCGTGAACAA


 


51
AACCCTCATC CTCGCCCTTT CCGCCCTCCT CGGCCTTGCC GCGTGCAGTG


 


101
CCGAACGCGT TTCACTGTTC CCCTCGTACA AACTCAAAAT CATACAGGGC


 


151
AACGAACTCG AACCGCGCGC CGTTGCCGCC CTCCGCCCCG GCATGACCAA


 


201
AGACCAAGTC CTGCTCCTGC TCGGCAGCCC CATACTGCGC GACGCATTCC


 


251
ATACCGACCG CTGGGACTAT ACCTTCAACA CCTCCCGCAA CGGCATCATC


 


301
AAAGAACGCA GCAATCTGAC CGTCTATTTT GAAAACGGCG TACTCGTCCG


 


351
CACCGAAGGC GACGTCCTGC AAAACGCTGC CGAAGCCCTC AAAGACCGCC


 


401
AAAACACAGA CAAACCATAA






This corresponds to the amino acid sequence <SEQ ID 2288; ORF 688>:










m688.pep




1
VLHYPSRFAQ KGISVNKTLI LALSALLGLA ACSAERVSLF PSYKLKIIQG


 


51
NELEPRAVAA LRPGMTKDQV LLLLGSPILR DAFHTDRWDY TFNTSRNGII


 


101
KERSNLTVYF ENGVLVRTEG DVLQNAAEAL KDRQNTDKP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 688 shows 90.6% identity over a 138 aa overlap with a predicted ORF (ORF 688) from N. gonorrhoeae: 

m688/g688 90.6% identity in 138 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2289>










a688.seq




1
GTGTTACACT ACCCATCCCG ATTTGCACAG AAAGGCATTT CCGTGAACAA


 


51
AACCCTCATC CTCGCCCTTT CCGCCCTCCT CGGCCTTGCC GCGTGCAGCG


 


101
TCGAACGCGT TTCACTGTTC CCCTCGTACA AACTCAAAAT CATACAGGGC


 


151
AACGAACTCG AACCTCGCGC CGTCGCCTCC CTCCGCCCCG GTATGACCAA


 


201
AGACCAAGTC CTGCTCCTGC TCGGCAGCCC CATACTGCGC GACGCATTCC


 


251
ATACCGACCG CTGGGACTAT ACCTTCAACA CCTCCCGCAA CGGCATCATC


 


301
AAAGACCGAA GCAATCTGAC CGTCTATTTT GAAAACGGCG TGCTCGTCCG


 


351
CACCGAAGGC AACGCCCTGC AAAATGCCGC CGAAGCCCTC CGCGTAAAAC


 


401
AAAACGCAGA CAAACAATAA






This corresponds to the amino acid sequence <SEQ ID 2290; ORF 688.a>:










a688.pep




1
VLHYPSRFAQ KGISVNKTLI LALSALLGLA ACSVERVSLF PSYKLKIIQG


 


51
NELEPRAVAS LRPGMTKDQV LLLLGSPILR DAFHTDRWDY TFNTSRNGII


 


101
KDRSNLTVYF ENGVLVRTEG NALQNAAEAL RVKQNADKQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 688 shows 93.5% identity over a 138 aa overlap with a predicted ORF (ORF 688) from N. meningitidis 

m688/a688 93.5% identity in 138 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2291>









g689.seq (partial)










1
..TCTCCGCCCC TTCCTCCGAT GAGCGGAAAA CTGATGGCGG TTTTGATGGC



 


51
  GGTACTGGTC GCGCTGATGC CGTTTTCCAT CGATGCCTAC CTGCCCGCGA


 


101
  TTCCCGAAAT GGCGCAGCCG CTGAACGCGG ATATCCACCG TATCGAATAG


 


151
  AGTCTGAGTT TGTTTATGTT CGGCACGGCG TTCGGGCAAG TGGCCGGCGG


 


201
  CGCGGTGTCC GACATCAAAG GGCGCAAACC CGTCGCCCTG ACCGGTTTGA


 


251
  TTGTATATTG CCTTGCCGTT GCCGCCATCG TATTTGCTTC GAGTACCGAA


 


301
  CAGCTCCTTA ACCTGCGTGC GGTACAGGCG TTCGGCGCAG GCATGGCTGT


 


351
  AGTCATCGTc ggtgcgatgg tgcgcgatTA TTATTCCGGA CGCAAAGCCG


 


401
  cgcAGATGTT TGCCCTTATC GGCATCATTC TGATGGTTGT GCCGCTGGCC


 


451
  GCACCCATGG TCGGCGCATT GTTGCAGGGA TTGGGCGGAT GGCGGGCGAT


 


501
  TTTCGTTTTC ttggcGgcgT ATTCGCCGGT GCTGCCCGGT TTGGTACAGT


 


551
  ATTTCCTGCC CAATCCCGCC GTCGGCGGCA AAATCGGCAG GGATGTGTTC


 


601
  GGGCTGGTGG CGGGGCGGTT CAAGCGCGTA TTGAAAACCC GTGCCGCGAT


 


651
  GGGTtatCTG TTTTTTCAGG CATTCAGCTT CGGTTCGATG TTCGCCTTTC


 


701
  TGACCGAATC TTCCTTCGTG TACCGGCAGC TCTACCACGT TACGCCGCAC


 


751
  CGGTACGCAT GGGTGTTTGC ACTCAACATC ATCACGATGA TGTTTTTCAG


 


801
  CCGCGTTACC GCGTGGCGGC TTAAAACCGG CGCGCATCCG CAAAGCATCC


 


851
  TGCTGCGGGG GATTGTCGTC CAATTTGCCG CCAACCCGTC CCAACTCGCC


 


901
  GCCGTGCTGT TTTTCGGGTT GCCCCCGTTT TGGCTGCCGG TCGCGTGCGT


 


951
  GATGTTTTCC GTCGGTACGC AGGGCCTGGT CGGTGCGGAC ACGCAGGCAT


 


1001
  GCTTTATGTC TTATTTCAAA GAAGAGGGCG GCAGCGCGAA CGCCGTGTCG


 


1051
  GGTGTATTCC GGTCCTTAAT CGGCGCGGGC GTGGTCATGG CGGCAACCGT


 


1101
  GATGGCGGCA ACCATGACCG CGTCCGCCTC TTGCGGCATT GCGCTTTTGT


 


1151
  GGCTCTGCTC GCACAAGGCG TGGAAGGAAA ACGAAAAAAA GCGAATACTT






This corresponds to the amino acid sequence <SEQ ID 2292; ORF 689>:









g689.pep (partial)










1
..SPPLPPMSGK LMAVLMAVLV ALMPFSIDAY LPAIPEMAQP LNADIHRIE*



 


51
  SLSLFMFGTA FGQVAGGAVS DIKGRKPVAL TGLIVYCLAV AAIVFASSTE


 


101
  QLLNLRAVQA FGAGMAVVIV GAMVRDYYSG RKAAQMFALI GIILMVVPLA


 


151
  APMVGALLQG LGGWRAIFVF LAAYSPVLPG LVQYFLPNPA VGGKIGRDVF


 


201
  GLVAGRFKRV LKTRAAMGYL FFQAFSFGSM FAFLTESSFV YRQLYHVTPH


 


251
  RYAWVFALNI ITMMFFSRVT AWRLKTGAHP QSILLRGIVV QFAANPSQLA


 


301
  AVLFFGLPPF WLPVACVMFS VGTQGLVGAD TQACFMSYFK EEGGSANAVS


 


351
  GVFRSLIGAG VVMAATVMAA TMTASASCGI ALLWLCSHKA WKENEKKRIL






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2293>:










m689.seq




1
TTGTTAATCC ACTATATCGT TCCGGTTCGT CCGGTTTTGC CGGGGCTTTT


 


51
GTTGCCGCCT GTTTGTGCCG GTGTGTTAAA ATTTTCCGTT TCCGCGTATT


 


101
GTGTTTTCCG CCGCCGGGCG GTTTGTTTGC GAATCGGACG AGAATTTATG


 


151
CCTTCTGCCC ATTATCCTGA AATGAGCGAA AAACTGATGG CGGTTTTGAT


 


201
GGCGATGCTG GTTACGCTGA TGCCGTTTTC CATCGATGCC TACCTGCCCG


 


251
CGATTCCCGA AATGGCGCAA TCGCTGAACG CGGATGTTCA CCGCATCGAA


 


301
CAGAGTTTGA GTTTGTTTAT GTTCGGCACG GCGTTCGGAC AGGTGGTCGG


 


351
CGGTTCGGTG TCCGACATCA AAGGGCGCAA ACCCGTCGCC CTGACCGGTT


 


401
TGATTGTATA TTGCCTTGCC GTTGCCGCCA TCGTATTTGT TTCGAGTGCC


 


451
GAACAGCTCC TCAACCTGCG CGTCGTGCAG GCATTCGGTG CGGGCATGAC


 


501
TGTGGTCATC GTCGGCGCAA TGGTGCGCGA TTATTATTCC GGACGCAAAG


 


551
CCGCCCAGAT GTTTGCCCTT ATCGGCATCA TTTTGATGGT TGTGCCGCTG


 


601
GTCGCACCCA TGGTCGGCGC ATTGTTGCAG GGCTTGGGTG GCTGGCAGGC


 


651
GATTTTTGTT TTTCTGGCGG CGTATTCGCT GGTGCTGCTC GGTTTGGTAC


 


701
AGTATTTCCT GCCCAAGCCC GCCGTCGGCG GCAAAATCGG ACGGGACGTG


 


751
TTCGGGCTGG TGGCGGGGCG GTTCAAGCGC GTATTGAAAA CCCGTGCTGC


 


801
GATGGGTTAT CTGTTTTTTC AGGCATTCAG CTTCGGTTCG ATGTTCGCCT


 


851
TTCTGACCGA ATCTTCCTTC GTGTACCAGC AGCTCTACCG TGTTACGCCT


 


901
CATCAATACG CTTGGGCGTT TGCACTCAAC ATCATCACGA TGATGTTTTT


 


951
CAACCGCGTT ACCGCGTGGC GGCTCAAAAC CGGCGTGCAT CCGCAAAGCA


 


1001
TCCTGCTGTG GGGGATTGTC GTCCAGTTTG CCGCCAACCT GTCCCAACTC


 


1051
GCCGCCGTGC TGTTTTTCGG GTTGCCCCCG TTTTGGCTGC TGGTCGCGTG


 


1101
CGTGATGTTT TCCGTCGGTA CGCAGGGCTT GGTCGGTGCA AACACGCAGG


 


1151
CGTGTTTTAT GTCCTATTTC AAAGAAGAGG GCGGCAGCGC AAACGCCGTA


 


1201
TTGGGTGTAT TCCAATCTTT AATCGGCGCG GGGGTGGGTA TGGCGGCGAC


 


1251
CTTCTTGCAC GACGGTTCGG CAACCGTGAT GGCGGCAACG ATGACCGCGT


 


1301
CCACCTCTTG CGGCATTGCG CTTCTGTGGC TCTGCTCGCA TCGTGCGTGG


 


1351
AAAGAAAACG GGCAAAGCGA ATACCTTTAA






This corresponds to the amino acid sequence <SEQ ID 2294; ORF 689>:










m689.pep




1
LLIHYIVPVR PVLPGLLLPP VCAGVLKFSV SAYCVFRRRA VCLRIGREFM


 


51
PSAHYPEMSE KLMAVLMAML VTLMPFSIDA YLPAIPEMAQ SLNADVHRIE


 


101
QSLSLFMFGT AFGQVVGGSV SDIKGRKPVA LTGLIVYCLA VAAIVFVSSA


 


151
EQLLNLRVVQ AFGAGMTVVI VGAMVRDYYS GRKAAQMFAL IGIILMVVPL


 


201
VAPMVGALLQ GLGGWQAIFV FLAAYSLVLL GLVQYFLPKP AVGGKIGRDV


 


251
FGLVAGRFKR VLKTRAAMGY LFFQAFSFGS MFAFLTESSF VYQQLYRVTP


 


301
HQYAWAFALN IITMMFFNRV TAWRLKTGVH PQSILLWGIV VQFAANLSQL


 


351
AAVLFFGLPP FWLLVACVMF SVGTQGLVGA NTQACFMSYF KEEGGSANAV


 


401
LGVFQSLIGA GVGMAATFLH DGSATVMAAT MTASTSCGIA LLWLCSHRAW


 


451
KENGQSEYL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 689 shows 88.0% identity over a 408 aa overlap with a predicted ORF (ORF 689) from N. gonorrhoeae: 

m689/a689 88.0% identity in 408 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2295>










a689.seq




1
TTGTTAATCC ACTATATCGT TCCGGTTCGT CCGGTTTTGC CGGGGCTTTT


 


51
GTTGCCGCCT GTTTGTGCCG GTGTGTTAAA ATTTTCCGTT TCCGCGTATT


 


101
GTGTTTTCCG CCGCCGGGCG GTTTGTTTGC GAATCGGACG AGAATTTATG


 


151
CCTTCTGCCC ATTATCCTGA AATGAGCGAA AAACTGATGG CGGTTTTGAT


 


201
GGCGATGCTG GTTACGCTGA TGCCGTTTTC CATCGATGCC TACCTGCCCG


 


251
CGATTCCCGA AATGGCGCAG TCGCTGAACG CGGATGTCCA CCGCATCGAA


 


301
CAGAGCCTGA GTTTGTTTAT GTTCGGCACG GCGTTCGGAC AGGTGGTCGG


 


351
CGGTTCGGTG TCCGACATCA AAGGGCGCAA ACCCGTCGCG CTGACCGGAC


 


401
TGGCCGTCTA CTGCCTTGCC GTTGCCGCCA TCGTATTTGC TTCGAGTGCC


 


451
GAACAGCTCC TCAACCTGCG CGTCGTGCAG GCATTCGGTG CGGGCATGAC


 


501
TGTGGTCATC GTCGGCGCAA TGGTGCGCGA TTATTATTCC GGACGCAAAG


 


551
CCGCCCAGAT GTTTGCCCTT ATCGGCATCA TTTTGATGGT TGTGCCGCTG


 


601
GTCGCACCCA TGGTCGGCGC ATTGTTGCAG GGCTTGGGTG GCTGGCAGGC


 


651
GATTTTTGTT TTTCTGGCGG CGTATTCGCT GGTGCTGCTC GGTTTGGTAC


 


701
AGTATTTCCT GCCCAAGCCC GCCGTCGGCG GCAAAATCGG CAGGGATGTG


 


751
TTCGGGCTGG TGGCTGGGCG GTTCAAACGC GTATTGAAAA CCCGTGCCGC


 


801
GATGGGTTAT CTGTTTTTTC AGGCATTCAG CTTCGGTTCG ATGTTCGCCT


 


851
TTCTGACCGA ATCTTCCTTC GTGTACCAGC AGCTCTACCA CGTTACGCCG


 


901
CACCAGTACG CTTGGGCGTT TGCACTCAAC ATCATCACGA TGATGTTTTT


 


951
CAACCGTATT ACCGCGTGGC GGCTCAAAAC CGGCGTGCAT CCGCAAAGCA


 


1001
TCCTGCTGTG GGGGATTGTC GTCCAGTTTG CCGCCAACCT GTCCCAACTC


 


1051
GCCGCCGTGC TGTTTTTCGG GTTGCCCCCG TTTTGGCTGC TGGTCGCGTG


 


1101
CGTGATGTTT TCCGTCGGTA CGCAGGGCTT GGTCGGTGCA AACACGCAGG


 


1151
CGTGTTTTAT GTCCTATTTC AAAGAAGAGG GCGGCAGCGC AAACGCCGTA


 


1201
TTGGGTGTAT TCCAATCTTT AATCGGCGCG GGGGTGGGTA TGGCGGCGAC


 


1251
CTTCTTGCAC GACGGTTCGG CAACCGTGAT GGCGGCAACC ATGACCGCGT


 


1301
CTACCTCTTG CGGCATTGCG CTTTTGTGGC TCTGCTCGCA TCGTGCGTGG


 


1351
AAAGAAAACG GGCAAAGCGA ATACCTTTAA






This corresponds to the amino acid sequence <SEQ ID 2296; ORF 689.a>:










a689.pep




1
LLIHYIVPVR PVLPGLLLPP VCAGVLKFSV SAYCVFRRRA VCLRIGREFM


 


51
PSAHYPEMSE KLMAVLMAML VTLMPFSIDA YLPAIPEMAQ SLNADVHRIE


 


101
QSLSLFMFGT AFGQVVGGSV SDIKGRKPVA LTGLAVYCLA VAAIVFASSA


 


151
EQLLNLRVVQ AFGAGMTVVI VGAMVRDYYS GRKAAQMFAL IGIILMVVPL


 


201
VAPMVGALLQ GLGGWQAIFV FLAAYSLVLL GLVQYFLPKP AVGGKIGRDV


 


251
FGLVAGRFKR VLKTRAAMGY LFFQAFSFGS MFAFLTESSF VYQQLYHVTP


 


301
HQYAWAFALN IITMMFFNRI TAWRLKTGVH PQSILLWGIV VQFAANLSQL


 


351
AAVLFFGLPP FWLLVACVMF SVGTQGLVGA NTQACFMSYF KEEGGSANAV


 


401
LGVFQSLIGA GVGMAATFLH DGSATVMAAT MTASTSCGIA LLWLCSHRAW


 


451
KENGQSEYL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 689 shows 99.1% identity over a 459 aa overlap with a predicted ORF (ORF 689) from N. meningitidis: 

m689/a689 99.1% identity in 459 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2297>









g690.seq (partial)










1
ATGAAAAACA AAACGTCATC ACTTCCCTTA TGGCTTGCCG CAATCATGCT



 


51
GGCCGCGCGT TCCCCGAGCA AAGAAGATAA AACGAAAGAA AACGGCGCAT


 


101
CCGCCGCTTC GTCTTCCGCG TCATCGGCTT CTTCCCAAAC CGATTTGCAA


 


151
CCGGCCGCAT CCGCCCCTGA TAACGTCAAG CAGGCAGAAA GCGCGCCACT


 


201
GTGAAATTGC ACCGGCCTGC ACCCCGCCGC CGGCATTGGC GATCTCATAC


 


251
AGCAAATCGC CGAACACATC GACTCGGACT GTCTGTTTGC CCTTTCCCAT


 


301
AACGAACTGG AAACCCGTTT CGGCTTACCC GGCGGCGGCT ATGACAACAT


 


351
ACAGCGGctG CTgtttCCCG ACATCCGCCC TGAAGATCCC GACTACCATC


 


401
AGAAAATCAT GCTGGCAATC GAAGACTTGC GTTACGGAAC GCGCACCATC


 


451
AGccgGCAGG CACAAGATGC CATAATGGAA CAGGAACGCC gcctccGaGa


 


501
agCGACGCTG ATGCTGACAC AGGGCAGTCA AAAAACCCGC GGaCAAGGCG


 


551
AGGAACCGAA ACGCGCACGT TATTTTGAAG TTTCGGCAAC ATCtgCCtaT


 


601
TTgaaccggC ACAAcaacGG ACTTggcgGC AATTTCCAAT ACATCGGCCA


 


651
ATTGCCCGGC TATCTGAAAA TGCACGGAGA AATGCTTGAA AACCAATCAC


 


701
TCTTCCGGCT GTCCAACCGT GAACGCAATC CCGACAAACC GTTTTTAGAC


 


751
ATCCATTTTG ACGAAAATGG CAAAATCACG CGTATTGTCG TTTACGAAAA


 


801
AAATATCTAT...






This corresponds to the amino acid sequence <SEQ ID 2298; ORF 690>:









g690.pep (partial)










1
MKNKTSSLPL WLAAIMLAAR SPSKEDKTKE NGASAASSSA SSASSQTDLQ



 


51
PAASAPDNVK QAESAPL*NC TGLHPAAGIG DLIQQIAEHI DSDCLFALSH


 


101
NELETRFGLP GGGYDNIQRL LFPDIRPEDP DYHQKIMLAI EDLRYGTRTI


 


151
SRQAQDAIME QERRLREATL MLTQGSQKTR GQGEEPKRAR YFEVSATSAY


 


201
LNRHNNGLGG NFQYIGQLPG YLKMHGEMLE NQSLFRLSNR ERNPDKPFLD


 


251
IHFDENGKIT RIVVYEKNIY ...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2299>:










m690.seq..




1
ATGAAAAACA AAACCTCATC ACTTCTCTTA TGGCTTACCG CAATCATGCT


 


51
GACCGCGTGT TCTCCGAGCA AAGACGATAA AACCAAAGAA GTCGGTGCAT


 


101
CCGCTGCTTC GTCCTCCGCG TCATCAGCTC CTTCCCAAAC CGATTTGCAA


 


151
CCGACCGCAT CCGCCCCTGA TAACGTCAAG CAGGCAGAAA GCGCGCCGCC


 


201
GTCAAATTGC ACCAGCCTGC ACCCCGCCAC CGGCATTGAC GATCTCATGC


 


251
AGCAAATCGC CGAACACATT GACTCGGACT GTCTGTTTGC CCTTTCCCAT


 


301
CACGAACTGG AAACCCGTTT CGGCTTACCC GACGGTGGCT ATGACAACAT


 


351
ACAGCGGCTG CTGTTTCCCG ACATCCGCCC TGAAGATCCC GACTACCATC


 


401
AGAAAATCAT ACTGGCAATT GAAGACTTGC GTTACGGAAA GCGCACGATC


 


451
AGCCGGCAGG CACAAAATGC CTTGATGGAA CAGGAACGCC GCCTCCGAGA


 


501
AGCGACGCTG TTGCTGATAC AGGGCAGTCA AGAAACCCGC GGACAAGGCG


 


551
AGGAGCCGAA ACGCACGCGT TATTTTGAAG TTTCGGCAAC CCCTGCCTAT


 


601
TCGAGCCGGC ACAACAACGG ACTTGGCGGC AATTTCCAAT ACATCAGCCA


 


651
ATTGCCCGGC TATCTGAAAA TACACGGAGA AATGCTTGAA AACCAATCAC


 


701
TCTTCCGGCT GTCCAACCGT GAACGCAATC CCGACAAACC GTTTTTAGAC


 


751
ATCCATTTTG ACGAAAATGG CAAAATCACG CGTATTGTCG TTTACGAAAA


 


801
AAACATCTAC TTCAATCCAA ACACGGGGCG AATATAA






This corresponds to the amino acid sequence <SEQ ID 2300; ORF 690>:










m690.pep




1
MKNKTSSLLL WLTAIMLTAC SPSKDDKTKE VGASAASSSA SSAPSQTDLQ


 


51
PTASAPDNVK QAESAPPSNC TSLHPATGID DLMQQIAEHI DSDCLFALSH


 


101
HELETRFGLP DGGYDNIQRL LFPDIRPEDP DYHQKIILAI EDLRYGKRTI


 


151
SRQAQNALME QERRLREATL LLIQGSQETR GQGEEPKRTR YFEVSATPAY


 


201
SSRHNNGLGG NFQYISQLPG YLKIHGEMLE NQSLFRLSNR ERNPDKPFLD


 


251
IHFDENGKIT RIVVYEKNIY FNPNTGRI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 690 shows 89.3% identity over a 408 aa overlap with a predicted ORF (ORF 690) from N. gonorrhoeae: 

m690/g690 89.3% identity in 408 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2301>










a690.seq




1
ATGAAAAACA AAACCTCATC ACTTCTCTTA TGGCTTGCCG CAATGATGCT


 


51
GACCGCGTGT TCCCCGAGCA AAGAAGATAA AACGAAAGAA AACGGCGCAT


 


101
CCGCCGCCTC GTCCACGGCA TCCGCCGCTT CGTCTTCCGC GCCCCAAACC


 


151
GATTTGCAAC CGGCCGCATC CGCCCCTGAT AACGTCAAGC AGGCAGAAAG


 


201
CGTGCCGCCG TCAAATTGCA CCGACCTGCA CCCCGCCACC GGCATTGACG


 


251
ATCTCATGCA GCAAATCGCC GAACACATTG ACTCGGACTG TCTGTTTGCC


 


301
CTTTCCCATC ACGAACTGGA AACCCGTTTC GGCTTACCCG GCGGCGGCTA


 


351
TGACAACATA CAGCGGCTGC TGTTTCCCGA CATCCGCCCT GAAGATCCCG


 


401
ACTACCATCA GAAAATCATA CTGGCAATTG AAGACTTGCG TTACGGAAAG


 


451
CGCACGATCA GCCGGCAGGC ACAAGATGCC TTGATGGAAC AGGAACGCCG


 


501
CCTCCGAGAA GCGACGCTGT TGCTGATACA GGGCAGTCAA GAAACCCGCG


 


551
GACAAGGCGA GGAGCCGAAA CGCACGCGTT ATTTTGAAGT TTCGGCAACC


 


601
CCTGCCTATT CGAGCCGGCA CAACAACGGA CTTGGCGGCA ATTTCCAATA


 


651
CATCGGCCAA TTGCCCGGCT ATCTGAAAAT ACACGGAGAA ATGCTTGAAA


 


701
ACCAATCACT CTTCCGGCTG TCCAACCGTG AACGCAATCC CGACAAACCG


 


751
TTTTTAGACA TCCATTTTGA CGAAAATGGC AAAATCACGC GTATTGTCGT


 


801
TTACGAAAAA AACATCTACT TCAATCCAAA CTTGGGGCGA AGATAA






This corresponds to the amino acid sequence <SEQ ID 2302; ORF 690.a>:










a690.pep




1
MKNKTSSLLL WLAAMMLTAC SPSKEDKTKE NGASAASSTA SAASSSAPQT


 


51
DLQPAASAPD NVKQAESVPP SNCTDLHPAT GIDDLMQQIA EHIDSDCLFA


 


101
LSHHELETRF GLPGGGYDNI QRLLFPDIRP EDPDYHQKII LAIEDLRYGK


 


151
RTISRQAQDA LMEQERRLRE ATLLLIQGSQ ETRGQGEEPK RTRYFEVSAT


 


201
PAYSSRHNNG LGGNFQYIGQ LPGYLKIHGE MLENQSLFRL SNRERNPDKP


 


251
FLDIHFDENG KITRIVVYEK NIYFNPNLGR R*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 690 shows 93.9% identity over a 280 aa overlap with a predicted ORF (ORF 690) from N. meningitidis: 

m690/a690 93.9% identity in 280 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2303>










g691.seq




1
GTGCCGCTGC CTGCTCCCTG CCGTTTTGCC AAACCTGCCG CCTCTTTTTT


 


51
AAGTATGGCT TTGCTTTCCT GCCAGCTTTC CCACGCCGCC ACGGCTTATA


 


101
TCCCCCCGAA CGATTTTCAA CCGAACTGCG ACATACGCCG GCTCGGGCTG


 


151
ACACAGGGTC AGCACAATGA GCTGCGTAAA ATCCGCGCCG CCTTCAAAAT


 


201
GGCGGGCGAC AGGGCGCGTT TGAAGGTTAT GCATTCCGAA CACAGCCGCC


 


251
GCCGCTCTGT CGTCGAAATC ATTTCTTCGG ATGTTTTTAA TCGGAACGAG


 


301
GCGCGCGATT ATGTCGAAAG CCGCTACCAC TCCAGCATGG ATTTTGCGGT


 


351
GGACGAATTG GAAATCCAAC ACCGCTTCTT CCATATTCTC ACACCGCAAC


 


401
AGCAGCAAAT GTGGCTTTCT TCCTGCCTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 2304; ORF 691>:










g691.pep




1
VPLPAPCRFA KPAASFLSMA LLSCQLSHAA TAYIPPNDFQ PNCDIRRLGL


 


51
TQGQHNELRK IRAAFKMAGD RARLKVMHSE HSRRRSVVEI ISSDVFNRNE


 


101
ARDYVESRYH SSMDFAVDEL EIQHRFFHIL TPQQQQMWLS SCLK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2305>:










m691.seq




1
GTGCCACTGC CTGCTCCCTG CCGTTTTGCC AAACCTGCCG CCTCTTTTTT


 


51
AAGTATGGCT TTGCTTTCCT GTCAGCTTTC CCACGCCGCC ACGGCTTATA


 


101
TCCCCCCGAA CGATTTTCAA CCGAACTGCG ACATACGCCG ACTCGGGCTG


 


151
ACCCAAAGTC AGCACAATGA GCTGCGTAAA ATCCGCACCG CCTTCAAAAT


 


201
GGCGGGCGAC AGGGCGCGTT TGAAGGTTAT GCATTCCGAA CACAGCCGCC


 


251
GCCGGTCTGT CGTCGAAATC ATTTCCTCGG ATGTTTTTAA TCGGAACGAG


 


301
GCGCGCGATT ATGTCGAAAG CCGCTATTTG TCCGGTATGG ATTTTGCGGT


 


351
GGACGAATTG GAAATCCAAC ACCGGTTCTT CCATATCCTC ACACCGCAAC


 


401
AGCAGCAAAT GTGGCTTTCT TCCTGCCTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 2306; ORF 691>:










m691.pep




1
VPLPAPCRFA KPAASFLSMA LLSCQLSHAA TAYIPPNDFQ PNCDIRRLGL


 


51
TQSQHNELRK IRTAFKMAGD RARLKVMHSE HSRRRSVVEI ISSDVFNRNE


 


101
ARDYVESRYL SGMDFAVDEL EIQHRFFHIL TPQQQQMWLS SCLK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 691 shows 97.2% identity over a 144 aa overlap with a predicted ORF (ORF 691) from N. gonorrhoeae: 

m691/g691 97.2% identity in 144 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2307>










a691.seq




1
GTGCCACTGC NTGCTCCCTG CCGTTTTGCC AAACCTGCCG CCTCTTTTTT


 


51
AAGTATGGCT TTGCTTTCCT GCCAGCTTTC CCACGCCGCC ACGGCTTATA


 


101
TCCCCCTGAA CGATTTTCAA CCGAACTGCG ACATACGCCG GCTCGGACTG


 


151
ACACAGGGTC AGCACAATGA ACTGCGTAAA ATCCGCGCCG CCTTCAAAAT


 


201
GGCGGGCGAC AGGGCGCGTT TGAAGGTTAT GCATTCCGAA CACAGCCGCC


 


251
GTCGGTCTGT CGTCGAAATC ATTTCCTCGG ATGTTTTTAA TCGGAACGAG


 


301
GCGCGCGATT ATGTCGAAAG CCGCTATTTG TCCGGTATGG ATTTTGCGGT


 


351
GGACGAATTG GAAATCCAAC ACCGGTTCTT CCATATCCTC ACACCGCAAC


 


401
AGCAGCAAAT GTGGCTTTCT TCCTGCCTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 2308; ORF 691.a>:










a691.pep




1
VPLXAPCRFA KPAASFLSMA LLSCQLSHAA TAYIPLNDFQ PNCDIRRLGL


 


51
TQGQHNELRK IRAAFKMAGD RARLKVMHSE HSRRRSVVEI ISSDVFNRNE


 


101
ARDYVESRYL SGMDFAVDEL EIQHRFFHIL TPQQQQMWLS SCLK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 691 shows 97.2% identity over a 144 aa overlap with a predicted ORF (ORF 691) from N. meningitidis: 

m691/a691 97.2% identity in 144 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2309>










g692.seq




1
GTATCGCACA CACGCTGTCG CTGTTCGGAA TCGAtacGCC GGATTTGGCG


 


51
GAATGGCAGG GAATGGCGGA TTAAAGGACA AAAATGCCGT CTGAACACGG


 


101
ATGCGGTTCA GACGGCATCA TTTTATACGA CTGCCTTATT TGGCTGCGCC


 


151
TTCATTCCAT GCGGCAGGGT ATTTGTAGCC CTCGAAGCGT TTGTGCGCGT


 


201
AGGCTTTGAA CGCGTCGGAG TTATAGGCCT CGGTTACGTC TTTAAGCCAT


 


251
TGGCTGTCTT TGTCGGCGGT TTTgacGGCA GACCAGTTGA CATAGGCAAA


 


301
GCTCGGCTCT TGGAACAGGG CTTCGGTCAG CTTCATGCCG CTGCTTATGG


 


351
CGTAGTTGCC GTTGACGACG GCAAAATCCA CGTCGGCGCG GCTGCGCGGC


 


401
AGTTGTGCGG CTTCAAGCTC GACGATTTTG ATGTTTTTCA GGTTTTCCGC


 


451
GATGTCGGCT TTGGATGCGG TCAGCGGATT GATGCCGTCT TTGAGTTTGA


 


501
TCCAACCCAG TTCGTTCAGC ATCACCAAGG CGCGTGCGAA GTTGGAcggG


 


551
TcgtTGGGCG CGGATACGGT GCTGCCGTCT TTGACTTCTT CCAGCGATTT


 


601
CAGTTTGCCC GGATACAGTC CCAAAGGCGC GGTCGGCACT TGGAAGGCTT


 


651
CGGTGATGTC CAGGTTGTGT TCTTTTTTGA AATCGTCAAG ATAGGGTTTG


 


701
TGTTGGAAGA CGTTGATGTC CAACTCGCCC TCCGCCAATG CCAGATTCGG


 


751
GCGCACATAG TCggTAAATT cgaccaatTT gacgGTGTag cCTTTTTTCT


 


801
CCAGCTCGgc tTGGATTTGT TCTTTGACCA TATcgccgaa gtcgcccacg


 


851
gTCGTGCCGA agacgaTTTC TTTTTTCGCc GcgcCGTTAT CGGCAGAAGG


 


901
GGCGGCGgca gaggctgcGG GCGCGCTGTC TTTTtgaccG ccgCAGGCTG


 


951
CGAGGATGAG CGCGAGtgcg gcggcggaaa ggGTTTTGAA GAAGGTTTTc


 


1001
atATTTTCTc ctga






This corresponds to the amino acid sequence <SEQ ID 2310; ORF 692>:










g692.pep




1
VSHTRCRCSE SIRRIWRNGR EWRIKGQKCR LNTDAVQTAS FYTTALFGCA


 


51
FIPCGRVFVA LEAFVRVGFE RVGVIGLGYV FKPLAVFVGG FDGRPVDIGK


 


101
ARLLEQGFGQ LHAAAYGVVA VDDGKIHVGA AARQLCGFKL DDFDVFQVFR


 


151
DVGFGCGQRI DAVFEFDPTQ FVQHHQGACE VGRVVGRGYG AAVFDFFQRF


 


201
QFARIQSQRR GRHLEGFGDV QVVFFFEIVK IGFVLEDVDV QLALRQCQIR


 


251
AHIVGKFDQF DGVAFFLQLG LDLFFDHIAE VAHGRAEDDF FFRRAVIGRR


 


301
GGGRGCGRAV FLTAAGCEDE RECGGGKGFE EGFHIFS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2311>:










m692.seq




1
GTGTTGCACA CGCTTTGTCG CTGTTCGGAA TCGATACGCC GGATTCGGCG


 


51
GAATGGCAGG GAATGGCGGA TTAAAGGACA AAAATGCCGT CTGAACACGG


 


101
ATACAGTTCA GACGGCATCA TTTTATACGA CTGCCTTATT TGGCTGCGCC


 


151
TTCATTCCAT GCGGCAGGGG ATTTGTAGCC CTCGAAGCGT TTGTGCGCGT


 


201
AGGCTTTGAA CGCGTCGGAG TTATAGGCCT CGGTTACGTC TTTAAGCCAT


 


251
TGGCTGTCTT TGTCGGCGGT TTTGACGGCA GACCAGTTGA CATAGGCAAA


 


301
GCTCGGTTCT TGGAACAGGG CTTCGGTCAG CTTCATGCCG CTGCTTATGG


 


351
CGTAGTTGCC GTTGACGACG GCAAAATCCA CGTCGGCGCG GCTACGCGGC


 


401
AGTTGCGCGG CTTCAAGCTC GACGATTTTG ATGTTTTTCA GGTTCTCGGC


 


451
GATGTCCGCT TTGGATGCGG TCAACGGATT GATGCCGTCT TTGAGTTTGA


 


501
TCCAACCCAG TTCGTCGAGC ATCACCAAGA CGCGGGCGAA GTTGGACGGG


 


551
TCGTTGGGCG CGGATACGGT GCTGCCGTCT TTGACTTCTT CCAGCGATTT


 


601
CAGCTTGCCC GGGTACAGTC CCAAAGGCGC GGTCGGCACT TGGAAGACTT


 


651
CGGTGATGTC CAGATTGTGT TCTTTTTTGA AGTCGTCAAG ATAGGGTTTG


 


701
TGTTGGAAGA CGTTGATGTC CAACTCGCCC TCAGCCAATG CCAGATTCGG


 


751
GCGTACATAG TCGGTAAACT CGACCAGTTT GACGGTGTAG CCTTTTTTCT


 


801
CCAGCTCGGC TTGGATTTGT TCTTTGACCA TATCGCCGAA GTCGCCGACG


 


851
GTCGTGCCGA AGACGATTTC TTTTTTCGCC GCGCCGTTGT CGGCGGCGGC


 


901
AGAAGCGGAT GCGGCGGGCG CGCTGTCTTT TTGACCGCCG CAGGCGGCGA


 


951
GGATGAGCGC GAGTGCGGCG GCGGAAAGGG TTTTGAAGAA GGTTTTCATA


 


1001
TTTTCTCCTG A






This corresponds to the amino acid sequence <SEQ ID 2312; ORF 692>:










m692.pep




1
VLHTLCRCSE SIRRIRRNGR EWRIKGQKCR LNTDTVQTAS FYTTALFGCA


 


51
FIPCGRGFVA LEAFVRVGFE RVGVIGLGYV FKPLAVFVGG FDGRPVDIGK


 


101
ARFLEQGFGQ LHAAAYGVVA VDDGKIHVGA ATRQLRGFKL DDFDVFQVLG


 


151
DVRFGCGQRI DAVFEFDPTQ FVEHHQDAGE VGRVVGRGYG AAVFDFFQRF


 


201
QLARVQSQRR GRHLEDFGDV QIVFFFEVVK IGFVLEDVDV QLALSQCQIR


 


251
AYIVGKLDQF DGVAFFLQLG LDLFFDHIAE VADGRAEDDF FFRRAVVGGG


 


301
RSGCGGRAVF LTAAGGEDER ECGGGKGFEE GFHIFS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 692 shows 91.1% identity over a 338 aa overlap with a predicted ORF (ORF 692) from N. gonorrhoeae: 

m692/g692 91.1% identity in 338 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2313>










a692.seq




1
GTGTTGCACA CGCTTTGTCG CTGTTCGGAA TCGATACGCC GGATTCGGCG


 


51
GAATGGCAGG GAATGGCGGA TTAAAGGACA AAAATGCCGT CTGAACACGG


 


101
ATACGGTTCA GACGGCATCA TTTTATACGA CTGCCTTATT TGGCTGCGCC


 


151
TTCATTCCAT GCGGCAGGGG ATTTGTAGCC CTCGAAGCGT TTGTGCGCGT


 


201
AGGCTTTGAA CGCGTCGGAG TTATAGGCCT CGGTTACGTC TTTAAGCCAT


 


251
TGGCTGTCTT TGTCGGCGGT TTTGACGGCA GACCAGTTGA CATAGGCAAA


 


301
GCTCGGTTCT TGGAACAGGG CTTCGGTCAG CTTCATGCCG CTGCTTATGG


 


351
CGTAGTTGCC GTTGACGACG GCAAAATCCA CGTCGGCGCG GCTACGCGGC


 


401
AGTTGCGCGG CTTCAAGCTC GACGATTTTG ATGTTTTTCA GGTTTTCGGC


 


451
AATGTCCGCT TTGGATGCGG TCAGCGGATT GATGCCGTCT TTGAGTTTGA


 


501
TCCAACCCAG TTCGTCGAGC ATCACCAAGA CGCGGGCGAA GTTGGACGGG


 


551
TCGTTGGGCG CGGATACGGT GCTGCCGTCT TTGACTTCTT CCAGCGATTT


 


601
CAGCTTGCCC GGGTACAGTC CCAAAGGCGC GGTCGGCACT TGGAAGACTT


 


651
CGGTGATGTC CAGATTGTGT TCTTTTTTGA AGTCGTCAAG ATAGGGTTTG


 


701
TGTTGGAAGA CGTTGATGTC CAACTCGCCC TCAGCCAATG CCAGATTCGG


 


751
GCGCACATAG TCGGTAAACT CGACCAGTTT GACGGTGTAG CCTTTTTTCT


 


801
CCAGCTCGGG TTGGATTTGT TCTTTGACCA TATCGCCGAA GTCGCCGACG


 


851
GTCGTGCCGA AGACGATTTC TTTTTTCGCC GCGCCGTTGT CGGCGGCGGC


 


901
AGAAGCGGAT GCGGCGGGCG CGCTATCTTT TTGACCGCCG CAGGCGGCGA


 


951
GGATGAGCGC GAGTGCGGCG GCGGAAAGGG TTTTGAAGAA GGTTTTCATA


 


1001
TTTTCTCCTG A






This corresponds to the amino acid sequence <SEQ ID 2314; ORF 692.a>:










a692.pep




1
VLHTLCRCSE SIRRIRRNGR EWRIKGQKCR LNTDTVQTAS FYTTALFGCA


 


51
FIPCGRGFVA LEAFVRVGFE RVGVIGLGYV FKPLAVFVGG FDGRPVDIGK


 


101
ARFLEQGFGQ LHAAAYGVVA VDDGKIHVGA ATRQLRGFKL DDFDVFQVFG


 


151
NVRFGCGQRI DAVFEFDPTQ FVEHHQDAGE VGRVVGRGYG AAVFDFFQRF


 


201
QLARVQSQRR GRHLEDFGDV QIVFFFEVVK IGFVLEDVDV QLALSQCQIR


 


251
AHIVGKLDQF DGVAFFLQLG LDLFFDHIAE VADGRAEDDF FFRRAVVGGG


 


301
RSGCGGRAIF LTAAGGEDER ECGGGKGFEE GFHIFS*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 692 shows 98.8% identity over a 336 aa overlap with a predicted ORF (ORF 692) from N. meningitidis: 

m692/a692 98.8% identity in 336 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2315>:










g694.seq




1
TCGGCATTTG TGTTGCCCAA ACATCCGATG CCTGCGTTAA CGCCTGCGTC


 


51
AACGTTTGCA CAAATCGGGT TTGGTTTCGC CCTCGCGGCG CAGCTCCTTG


 


101
GGCAGGACGA ACACGATGCT TTCTTCCGCG CCCCCCCCTT CGCGCACGGT


 


151
TTCATGCCCC CATCCGCGTA TGGTTGCCAA TACTTCCCGC ACCAACACTT


 


201
CGGGCGCGGA CGCGCCTGCC GTTACGCCGA CTTTGCTTTT GCCTTCAAAC


 


251
CACGTGCGTT GCaggTAGGA CGCGTTGTCC ACCATATACG CATCGATTCC


 


301
GCGCGATGCC GCCACTTCGC GCAGGCGGTT GCTGTTGGAC GAATTGGGCG


 


351
AACCGACCAC AATCACGATG TCGCACTGTT CCGCCAGCTC TTTGACGGCG


 


401
GTTTGCCGGT TGGTCGTCGC ATAGCAGATG TCTTCCTTGT GCGGATTGCG


 


451
GATATTGGGG AAACGCGCGT TCAGCGCGGC GATGATGTCT TTGGTTTCAT


 


501
CGACCGAGAG CGTGGTTTGG CTGACATAGG CGAGTTTGTC GGGGTTTCTG


 


551
ACTTCGAGTT TTGCCACATC TCCGACCGTT TCGACCAAAA GCATTTTGCC


 


601
CGGTGCAAGC TGCCCCATCG TGCCTTCGAC CTCGGCGTGC CCCTTATGCC


 


651
CGATCATGAT GATTTCACAG TCTTGGGCAT CCAGTCGGGC GACTTCCTTA


 


701
TGCACTTTCG TCACCAGCGG GCAAGTCGCA TCAAATACCC GGAAACCGCG


 


751
CTCCGCCGCT TCCTGCTGCA CCGCCTTCGA TACGCCGTGT GCCGAATAAA


 


801
CCAGTGTCGC GCCCGGCGGC ACTTCCGCCA AGTCTTCGAT AAACACCGCG


 


851
CCTTTTTCGC GCAGGTTGTC CACGACGAAT TTGTTGTGGA CGACTTCGTG


 


901
GCGCACATAA ACCGGCGCGC CGAATTCTTC CAAAGCACGT TCGACAATAC


 


951
TGATTGCCCG ATCCACACCG GCGCAGAAGC CGCGCGGATT GGCAAGGATG


 


1001
ATGGTTTTTC CGTTCATAAG TTTTGCATTC CGTGTTCAGA CGGCATTCAC


 


1051
GTTTTTTTGC TNNATCTTTG CGATGGACGA TATTGTCAAG CACCGCCAAC


 


1101
ACCGCACCGA CGCAGATAA






This corresponds to the amino acid sequence <SEQ ID 2316; ORF 694>:









g694.pep (partial)










1
SAFVLPKHPM PALTPASTFA QIGFGFALAA QLLGQDEHDA FFRAPPFAHG



 


51
FMPPSAYGCQ YFPHQHFGRG RACRYADFAF AFKPRALQVG RVVHHIRIDS


 


101
ARCRHFAQAV AVGRIGRTDH NHDVALFRQL FDGGLPVGRR IADVFLVRIA


 


151
DIGETRVQRG DDVFGFIDRE RGLADIGEFV GVSDFEFCHI SDRFDQKHFA


 


201
RCKLPHRAFD LGVPLMPDHD DFTVLGIQSG DFLMHFRHQR ASRIKYPETA


 


251
LRRFLLHRLR YAVCRINQCR ARRHFRQVFD KHRAFFAQVV HDEFVVDDFV


 


301
AHINRRAEFF QSTFDNTDCP IHTGAEAARI GKDDGFSVHK FCIPCSDGIH


 


351
VFLLXLCDGR YCQAPPTPHR RR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2317>:










m694.seq




1
TTGGTTTCCG CATCCGGCAC ACGGCAAAAA TGCCGTCTGA AGCCTGTTCA


 


51
GACGGCATTT GTGTTGCCCA AACATTCAAC GCCTGCGTCA ACGTTTGCAC


 


101
AAATCGGGTT TGGTTTCGCC CTCGCGGCGC AACTCTTTGG GCAGGACGAA


 


151
CACAATGCTT TCTTCCGCAC CCTCGCCTTC GCGTACGGTT TCGTGCCCCC


 


201
ATCCGCGTAT GGTTGCCAGT ACTTCCCGCA CCAACACTTC GGGCGCGGAC


 


251
GCGCCTGCCG TTACGCCGAC TTTGTTTTTG CCCTCAAACC ATGCGCGTTG


 


301
CAGGTAGCCT GCATTATCCA CCATATACGC ATCGATTCCG CGCGATGCCG


 


351
CCACTTCGCG CAAGCGGTTG CTGTTGGACG AATTGGGCGA ACCGACCACA


 


401
ATCACGATGT CGCACTGTTC TGCCAACTCT TTGACGGCGG TTTGCCGGTT


 


451
GGTCGTCGCA TAGCAGATAT CTTCCTTGTG CGGATTGCGG ATATTGGGGA


 


501
AACGCGCGTT CAGCGCGGCG ATGATGTCTT TGGTTTCATC GACCGAGAGC


 


551
GTGGTTTGGC TGACATAGGC GAGTTTGTCG GGGTTTCTGA CTTCGAGTTT


 


601
TGCCACATCT CCGACCGTTT CGACCAAAAG CATTTTGCCC GGCGCAAGCT


 


651
GCCCCATCGT TCCTTCGACC TCGACGTGCC CCTTATGCCC GATCATGATG


 


701
ATTTCACAGT CTTGGGCATC CAGTCGGGCG ACTTCCTTAT GCACTTTCGT


 


751
CACCAGCGGG CAAGTCGCAT CAAACACGCG GAAACCGCgC TCCGCCGCTT


 


801
CTTGCCGCAC CGCCTTCGAT ACGCCGTGTG CCGAATAAAC CAGTGTCGCG


 


851
CCCGGCGGCA CTTCCGCCAA GTCTTCAATA AACACCGCAC CTTTTTCACG


 


901
CAGGTTGTCC ACGACGAATT TGTTGTGAAC GACTTCGTGG CGCACATAAA


 


951
TCGGCGCGCC GAACTCTTCC AAAGCACGTT CGACAATACT GATT GCCCGA


 


1001
TCCACACCAG CGCAGAAGCC GCGCGGATTG GCAAGGATGA TGGTTTTCTC


 


1051
GTTCATAAGC CCGGTATTTC GTTTTCAGAC GGCATCAATA TTTTTCTTCT


 


1101
TGGGTTTTAC GGTGGACGAT GTTGTCCAAC ACCGCCAACA CCGCACCGAC


 


1151
GCAGATAA






This corresponds to the amino acid sequence <SEQ ID 2318; ORF 694>:










m694.pep




1
LVSASGTRQK CRLKPVQTAF VLPKHSTPAS TFAQIGFGFA LAAQLFGQDE


 


51
HNAFFRTLAF AYGFVPPSAY GCQYFPHQHF GRGRACRYAD FVFALKPCAL


 


101
QVACIIHHIR IDSARCRHFA QAVAVGRIGR TDHNHDVALF CQLFDGGLPV


 


151
GRRIADIFLV RIADIGETRV QRGDDVFGFI DRERGLADIG EFVGVSDFEF


 


201
CHISDRFDQK HFARRKLPHR SFDLDVPLMP DHDDFTVLGI QSGDFLMHFR


 


251
HQRASRIKHA ETALRRFLPH RLRYAVCRIN QCRARRHFRQ VFNKHRTFFT


 


301
QVVHDEFVVN DFVAHINRRA ELFQSTFDNT DCPIHTSAEA ARIGKDDGFL


 


351
VHKPGISFSD GINIFLLGFY GGRCCPTPPT PHRRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 694 shows 86.8% identity over a 372 aa overlap with a predicted ORF (ORF 694) from N. gonorrhoeae: 

m694/g694 86.8% identity in 372 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2319>:










a694.seq




1
TTGGTTTCCG CATCCGGCAC ACGGCAAAAA TGCCGTCTGA AGCCTGTTCA


 


51
GACGGCATTT GTGTTGCCCA AACATTCAAC GCCTGCGTCA ACGTTTGCAC


 


101
AAATCGGGTT TGGTTTCGCC CTCGCGGCGC AACTCTTTGG GCAGGACGAA


 


151
CACAATGCTT TCTTCCGCAC CCTCGCCTTC GCGTACGGTT TCGTGCCCCC


 


201
ATCCGCGTAT GGTTGCCAGT ACTTCCCGCA CCAACACTTC GGGCGCGGAC


 


251
GCGCCTGCCG TTACGCCGAC TTTGTTTTTG CCCTCAAACC ATGCGCGTTG


 


301
CAGGTAGCCT GCATTATCCA CCATATACGC ATCGATTCCG CGCGATGCCG


 


351
CCACTTCGCG CAAGCGGTTG CTGTTGGACG AATTGGGCGA ACCGACCACA


 


401
ATCACGATGT CGCACTGTTC TGCCAACTCT TTGACGGCGG TTTGCCGGTT


 


451
GGTCGTCGCA TAGCAGATAT CTTCCTTGTG CGGATTGCGG ATATTGGGGA


 


501
AACGCGCGTT CAGCGCGGCG ATGATGTCTT TGGTTTCATC GACCGAGAGC


 


551
GTGGTTTGGC TGACATAGGC GAGTTTGTCG GGGTTTCTGA CTTCGAGTTT


 


601
TGCCACATCT CCGACCGTTT CGACCAAAAG CATTTTGCCC GGCGCAAGCT


 


651
GCCCCATCGT TCCTTCGACC TCGACGTGCC CCTTATGCCC GATCATGATG


 


701
ATTTCACAGT CTTGGGCATC CAGTCGGGCG ACTTCCTTAT GCACTTTCGT


 


751
CACCAGCGGG CAAGTCGCAT CAAACACGCG GAAACCGCGC TCCGCCGCTT


 


801
CTTGCCGCAC CGCCTTCGAT ACGCCGTGTG CCGAATAAAC CAGTGTCGCG


 


851
CCCGGCGGCA CTTCCGCCAA GTCTTCAATA AACACCGCAC CTTTTTCACG


 


901
CAGGTTGTCC ACGACGAATT TGTTGTGAAC GACTTCGTGG CGCACATAAA


 


951
TCGGCGCGCC GAACTCTTCC AAAGCACGTT CGACAATACT GATTGCCCGA


 


1001
TCCACACCAG CGCAGAAGCC GCGCGGATTG GCAAGGATGA TGGTTTTCTC


 


1051
GTTCATAAGC CCGGTATTTC GTTTTCAGAC GGCATCAATA TTTTTCTTCT


 


1101
TGGGTTTTAC GGTGGACGAT GTTGTCCAAC ACCGCCAACA CCGCACCGAC


 


1151
GCAGATAA






This corresponds to the amino acid sequence <SEQ ID 2320; ORF 694.a>:










a694.pep




1
LVSASGTRQK CRLKPVQTAF VLPKHSTPAS TFAQIGFGFA LAAQLFGQDE


 


51
HNAFFRTLAF AYGFVPPSAY GCQYFPHQHF GRGRACRYAD FVFALKPCAL


 


101
QVACIIHHIR IDSARCRHFA QAVAVGRIGR TDHNHDVALF CQLFDGGLPV


 


151
GRRIADIFLV RIADIGETRV QRGDDVFGFI DRERGLADIG EFVGVSDFEF


 


201
CHISDRFDQK HFARRKLPHR SFDLDVPLMP DHDDFTVLGI QSGDFLMHFR


 


251
HQRASRIKHA ETALRRFLPH RLRYAVCRIN QCRARRHFRQ VFNKHRTFFT


 


301
QVVHDEFVVN DFVAHINRRA ELFQSTFDNT DCPIHTSAEA ARIGKDDGFL


 


351
VHKPGISFSD GINIFLLGFY GGRCCPTPPT PHRRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 694 shows 100% identity over a 385 aa overlap with a predicted ORF (ORF 694) from N. meningitidis: 

m694/a694 100.0% identity in 385 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2321>:










g695.seq




1
TTGCCTCAAA CTCGTCCGGC AAGGCGGCAT CATCGCCATC GACAATATTT


 


51
TGTTGAACGG AAGGGTGATG CGCGAAGCGG CTTTTGATGC GCCGCCCAGT


 


101
GTCAAAATTC TCAAAGATTT CAATCAAAAC CTGCCGAACG ATACGCGGAT


 


151
TGTCCCCATC ACCCTGCCCG TCGGCGACGG TTTGACCCTG CTTCTGAAAA


 


201
AATAATGAAG ACCAAATTAC CGCTTTTTAT CATTTGGCTG TCTGTGTCTG


 


251
CCTCCTGTGC TTCCGTTTTA CCCGTTCCGG AGGGCAGCCG AACCGAAATG


 


301
CCGACACAGG AAAATGCTTC AGACGGCATT CCCTATCCCG TTCCCACTCT


 


351
GCAAGACCGT TTGGACTATC TGGAAGGCAA AATCGTCCGG CTGTCGAACG


 


401
AAGTGGAAAT GTTAAACGGG AAAGTCAAAG CATTGGAGCA TACGAAAATA


 


451
CACCCTTCCG GCAGGACATA CGTCCAAAAA CTCGACGACC GCAAATTGAA


 


501
AGAGCATTAC CTCAATACCG AAGGCGGCAG CGCATCCGCA CATACCGTCG


 


551
AAACCGCACA AAACCTCTAC AATCAGGCAC TCAAACACTA TCAAAACGGC


 


601
AGGTTTTCTG CCGCAGCCGC CTTGTTGAAG GGGGCGGACG GCGGAGACGG


 


651
CGGCAGCATC GCGCAACGCA GTATGTACCT GTTGCTGCAA AGCAGGGCGC


 


701
GTATGGGGAA CTGTGAATCT GTCATCGAAA TCGGAGGGCG TTACGCCAAC


 


751
CGTTTCAAAG ACAGCCCAAC CGCGCCCGAA GTCATATTCA AAATCGGCGA


 


801
ATGCCAATAC AGGCTTCAGC AAAAAGACAT TGCAAGGGCG ACTTGGCGCA


 


851
GCCTGATACA GACCTATCCC GGCAGCCCGG CGGCAAAACG CGCCGCCGCA


 


901
GCCGTACGCA AACGATAG






This corresponds to the amino acid sequence <SEQ ID 2322; ORF 695>:










g695.pep




1
LPQTRPARRH HRHRQYFVER KGDARSGF*C AAQCQNSQRF QSKPAERYAD


 


51
CPHHPARRRR FDPASEKIMK TKLPLFIIWL SVSASCASVL PVPEGSRTEM


 


101
PTQENASDGI PYPVPTLQDR LDYLEGKIVR LSNEVEMLNG KVKALEHTKI


 


151
HPSGRTYVQK LDDRKLKEHY LNTEGGSASA HTVETAQNLY NQALKHYQNG


 


201
RFSAAAALLK GADGGDGGSI AQRSMYLLLQ SRARMGNCES VIEIGGRYAN


 


251
RFKDSPTAPE VIFKIGECQY RLQQKDIARA TWRSLIQTYP GSPAAKRAAA


 


301
AVRKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2323>:










m695.seq




1
TTGCCTCAAA CTCGTCCGTC AAGGCGGCAT CATCGCCATC GACAATATTT


 


51
TGCTGAACGG AAGGGTGATG CGCGAAGCGG CTTCCGATGC GCCGCCCAGC


 


101
GTCGGCATCC TCAAAGATTT CAATCAAAAC CTGCCGAACG ACCCGCGCAT


 


151
CGTCCCCATC ACCCTGCCCG TCGGCGACGG CTTGACCCTG CTTCTGAAAA


 


201
AATAATGAAG ATCAAATTAC CGCTTTTTAT CATTTGGCTG TCTGTGTCCG


 


251
CCTCCTGTGC TTCCGTTTCA CCCGTTCCGG CAGGCAGCCA AACCGAAATG


 


301
TCGACACGGG AAAATGCTTC AGACGGCATT CCCTATCCCG TTCCGACCTT


 


351
GCAAGACCGT TTGGACTATC TGGAAGGCAA AATCGTCCGG CTGTCGAACG


 


401
AAGTGGAAAC CTTAAACGGC AAAGTCAAAG CACTGGAACA CGCAAAAACA


 


451
CATTCTTCCG GCAGGGCATA CGTCCAAAAA CTCGACGACC GCAAGTTGAA


 


501
AGAGCATTAC CTCAATACCG AAGGCGGCAG CGCATCCGCA CATACTGTCG


 


551
AAACCGCACA AAACCTCTAC AATCAGGCAC TCAAACACTA TAAAAGCGGC


 


601
AAGTTTTCTG CCGCTGCCTC CCTGTTGAAA GGCGCGGACG GAGGCGACGG


 


651
CGGCAGCATC GCGCAACGCA GTATGTACCT GTTGCTGCAA AGCAGGGCGC


 


701
GTATGGGCAA CTGCGAATCC GTCATCGAAA TCGGAGGGCG TTACGCCAAC


 


751
CGTTTCAAAG ACAGCCCAAC CGCGCCTGAA GCCATGTTCA AAATCGGCGA


 


801
ATGCCAATAC AGGCTTCAGC AAAAAGACAT TGCAAGGGCG ACTTGGCGCA


 


851
GCCTGATACA GACCTATCCC GGCAGCCCGG CGGCAAAACG CGCCGCCGCA


 


901
GCCGTGCGCA AACGATAG






This corresponds to the amino acid sequence <SEQ ID 2324; ORF 695>:










m695.pep




1
LPQTRPSRRH HRHRQYFAER KGDARSGFRC AAQRRHPQRF QSKPAERPAH


 


51
RPHHPARRRR LDPASEKIMK IKLPLFIIWL SVSASCASVS PVPAGSQTEM


 


101
STRENASDGI PYPVPTLQDR LDYLEGKIVR LSNEVETLNG KVKALEHAKT


 


151
HSSGRAYVQK LDDRKLKEHY LNTEGGSASA HTVETAQNLY NQALKHYKSG


 


201
KFSAAASLLK GADGGDGGSI AQRSMYLLLQ SRARMGNCES VIEIGGRYAN


 


251
RFKDSPTAPE AMFKIGECQY RLQQKDIARA TWRSLIQTYP GSPAAKRAAA


 


301
AVRKR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 694 shows 90.8% identity over a 305 aa overlap with a predicted ORF (ORF 695) from N. gonorrhoeae: 

m695/g695 90.8% identity in 305 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2325>:










a695.seq




1
TTGCCTCAAG CTTGTCCGGC AAGGCGGCAT CATTGCCATC GACAATATTT


 


51
TGTTGAACGG AAGGGTGATG CGCGAAGCGG CTTCCGATGC GCCGCCCAGC


 


101
GTCGGCATCC TCAAAGATTT TAATCAAAAC CTGCCGAACG ATACGCGGAT


 


151
TGTCCCCATC ACCCTGCCCG TCGGCGACGG TTTGACCCTG CTTCTGAAAA


 


201
AATAATGAAG ACCAAATTAC CGCTTTTTAT CATTTGGCTG TCCGTATCCG


 


251
CCGCCTGTTC TTCCCCTGTT TCCCGCAATA TTCAGGATAT GCGGCTCGAA


 


301
CCGCAGGCAG AGGCAGGTAG TTCGGACGCT ATTCCCTATC CCGTTCCCAC


 


351
TCTGCAAGAC CGTTTGGATT ATCTGGAAGG CACACTCGTC CGCCTGTCGA


 


401
ACGAAGTGGA AACCTTAAAC GGCAAAGTCA AAGCACTGGA GCATGCGAAA


 


451
ACACACCCTT CCAGCAGGGC ATACGTCCAA AAACTCGACG ACCGCAAGTT


 


501
GAAAGAGCAT TACCTCAATA CCGAAGGCGG CAGCGCATCC GCACATACCG


 


551
TCGAAACCGC ACAAAACCTC TACAATCAGG CACTCAAACA CTATAAAAGC


 


601
GGCAGGTTTT CTGCCGCTGC CTCCCTGTTG AAAGGCGCGG ACGGAGGCGA


 


651
CGGCGGCAGC ATCGCGCAAC GCAGTATGTA CCTGTTGCTG CAAAGCAGGG


 


701
CGCGTATGGG CAACTGCGAA TCCGTCATCG AAATCGGAGG GCGTTACGCC


 


751
AACCGTTTCA AAGACAGCCC AACCGCGCCT GAAGCCATGT TCAAAATCGG


 


801
CGAATGCCAA TACAGGCTTC AGCAAAAAGA CATTGCAAGG GCGACTTGGC


 


851
GCAGCCTGAT ACAGACCTAT CCCGGCAGCC CGGCGGCAAA ACGCGCCGCC


 


901
GCAGCCGTGC GCAAACGATA G






This corresponds to the amino acid sequence <SEQ ID 2326; ORF 695.a>:










a695.pep




1
LPQACPARRH HCHRQYFVER KGDARSGFRC AAQRRHPQRF *SKPAERYAD


 


51
CPHHPARRRR FDPASEKIMK TKLPLFIIWL SVSAACSSPV SRNIQDMRLE


 


101
PQAEAGSSDA IPYPVPTLQD RLDYLEGTLV RLSNEVETLN GKVKALEHAK


 


151
THPSSRAYVQ KLDDRKLKEH YLNTEGGSAS AHTVETAQNL YNQALKHYKS


 


201
GRFSAAASLL KGADGGDGGS IAQRSMYLLL QSRARMGNCE SVIEIGGRYA


 


251
NRFKDSPTAP EAMFKIGECQ YRLQQKDIAR ATWRSLIQTY PGSPAAKRAA


 


301
AAVRKR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 695 shows 88.3% identity over a 308 aa overlap with a predicted ORF (ORF 695) from N. meningitidis: 

m695/a695 88.3% identity in 308 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae 

g696.seq: not found

This corresponds to the amino acid sequence <ORF 696.ng>:

g696.pep: not found

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2327>:










m696.seq




1
TTGGGTTGCC GGCAGGCGGC ATCCCATCAT TTTTGCCAAG GCAACAAATT


 


51
ATTTGGCGGC ATCTTTCATT TTGTCTGCCG CTTCCTGAGT CGCGTCGGCA


 


101
GCTTTGTTCA AAGTATCTTT AGCTGCTTCA GTTACAGCTT CTTTGGCTTC


 


151
AGTTACAGCT TCCTCGGCAC TTGCCTTTGC ATCAGCCGCA GCATCTTTGA


 


201
CTTGGTCTTT CGCTTCTTCG ACGGCAGAAG CGGCAGACTC GGCGGCAGAA


 


251
GCCGCAGTGT CTTTAACATC GGACTCAACG GCTTGAACCG CTTCCTTAAC


 


301
CTCCTGTTTG GCTTCTTGCG AACAAGCTGC CAAGGCAGCC GCCATCATTG


 


351
CGGCAATCAA TAA






This corresponds to the amino acid sequence <SEQ ID 2328; ORF 696>:










m696.pep




1
LGCRQAASHH FCQGNKLFGG IFHFVCRFLS RVGSFVQSIF SCFSYSFFGF


 


51
SYSFLGTCLC ISRSIFDLVF RFFDGRSGRL GGRSRSVFNI GLNGLNRFLN


 


101
LLFGFLRTSC QGSRHHCGNQ *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2329>:










a696.seq




1
TTGGGTTGCC GGCAGGCGGC ATCCCATCAT TTTTGCCAAG GCAACAAATT


 


51
ATTTGGCGGC ATCTTTCATT TTGTCTGCCG CTTCCTGAGT CGCGTCGGCA


 


101
GCTTTGTTCA AAGTATCTTT AGCTGCTTCA GTTACAGCTT CTTTGGCTTC


 


151
AGTTACAGCT TCCTCGGCAC TTGCCTTTGC ATCAGCCGCA GCATCTTTGA


 


201
CTTGGTCTTT CGCTTCTTCG ACGGCAGAAG CGGCAGACTC GGCGGCAGAA


 


251
GCCGCAGTGT CTTTAACATC GGACTCAACG GCTTGAACCG CTTCCTTAAC


 


301
CTCCTGTTTG GCTTCTTGCG AACAAGCTGC CAAGGCAGCC GCCATCATTG


 


351
CGGCAATCAA TAA






This corresponds to the amino acid sequence <SEQ ID 2330; ORF 696.a>:










a696.pep




1
LGCRQAASHH FCQGNKLFGG IFHFVCRFLS RVGSFVQSIF SCFSYSFFGF


 


51
SYSFLGTCLC ISRSIFDLVF RFFDGRSGRL GGRSRSVFNI GLNGLNRFLN


 


101
LLFGFLRTSC QGSRHHCGNQ *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 696 shows 100.0% identity over a 120 aa overlap with a predicted ORF (ORF 696) from N. meningitidis: 

m696/a696 100.0% identity in 120 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2331>:










g700.seq




1
ATGAGCAGCC TGATGACGTT GTTTTCGGTA TTGGTACCGA TGTTTGCCGG


 


51
ATTTTTTATC CGTGTTCCCA AGCCTTACCT GCCCGCTTCG GACAAGGTGC


 


101
TGTCGGTTTT GGTGTATGCC GTGCTGCTGC TGATCGGCGT ATCGTTGTCG


 


151
CGCGTGGAGG ATTTGGGTTC GCGGTTGGGC GATATGGCGT TGACGGTTCT


 


201
GTGGCTGTTT GTTTGTACGG TAGGGGCGAA CCTGCTTGCC TTGGCAGTGT


 


251
TGGGAAAGTT GTCCCCGTGG CGGATAGGGG GAAAAGGGAA GGGCGTTTCG


 


301
GTCGGCGTGT CGGGCAGTGT GAGGCAGCTC GGATGCGTAC TGCTCGGTTT


 


351
TGTGTCCGGC AAATTGATGT GCGATATTTG GATGCCGTCT GAAAACGCGG


 


401
GTATGTACTG CCTGATGCTG CTGGTGTTCC TCATCGGCGT ACAGCTCAAA


 


451
AGTAGCGGCG TATCGTTGCG GCAGGTTTTG CTTAACCGGC GGGGCATCCG


 


501
GCTGTCGGTT TGGTTTATAT TGTCATCTCT TTCAGGCGGG CTGCTGTTTG


 


551
CCGCATCGGC AGATGGTGTG TCGTGGACGA AAGGTTTGGC GATGGCTTCC


 


601
GGCTTCGGTT GGTATTCCCT CTCGGGTTTG GTAATGACCG AGGCTTACGG


 


651
GGCGGTATGG GGCAGCATCA TGCTGCTGAA CGATTTGGCA CGAGAGCTGT


 


701
TTGCACTGGC ATTTATTCCG CTGCTGATGA AGCGTTTTCC GGATGCGGCG


 


751
GTGGGGGTCG GCGGCGCGAC CAGTATGGAT TTCACATTGC CCGTAATTCA


 


801
GGGTGCGGGC GGTTTGGAAG TCGTGCCGGT AGCGGTCAGC TTCGGCGTGG


 


851
TGGTCAATAT CGCCGCCCCG TTTCTGATGG TGGTGTTTTC CACGCTGGGC


 


901
TGA






This corresponds to the amino acid sequence <SEQ ID 2332; ORF 700>:










g700.pep




1
MSSLMTLFSV LVPMFAGFFI RVPKPYLPAS DKVLSVLVYA VLLLIGVSLS


 


51
RVEDLGSRLG DMALTVLWLF VCTVGANLLA LAVLGKLSPW RIGGKGKGVS


 


101
VGVSGSVRQL GCVLLGFVSG KLMCDIWMPS ENAGMYCLML LVFLIGVQLK


 


151
SSGVSLRQVL LNRRGIRLSV WFILSSLSGG LLFAASADGV SWTKGLAMAS


 


201
GFGWYSLSGL VMTEAYGAVW GSIMLLNDLA RELFALAFIP LLMKRFPDAA


 


251
VGVGGATSMD FTLPVIQGAG GLEVVPVAVS FGVVVNIAAP FLMVVFSTLG


 


301
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2333>:










m700.seq




1
ATGGACAGCC TGATGACGTT GCTTTCGGTA TTGATACCGA TGTTTGCCGG


 


51
ATTTTTTATC CGTGTGCCCA AGCCTTACCT GCCCGCTTTG GATAAGGTGC


 


101
TATCGGTCTT GGTGTATGCT GTGCTGCTGC TGATCGGCGT CTCGTTGTCG


 


151
CGCGTGGAGG ATTTGGGTTC GCGGTTGGAC GATATGGCGT TGACGGTTCT


 


201
GTGGCTGTTT GTTTGTACGG TCGGGGCGAA CCTGCTTGCT TTGGCAGTGT


 


251
TGGGAAAGTT ATTCCCGTGG CGGATAAAGG GGAAAGGGAA GGGCGTTTCG


 


301
GTCGGCGTGT CGGGCAGTGT GGGGCAGCTC GGATGCGTGC TGCTCGGATT


 


351
TGCATTCGGC AAACTGATGC GCGATATTTG GATGCCGTCT GAAAGCGCGG


 


401
GCATGTATTG TCTGATGCTG CTGGTGTTCC TCATCGGCGT ACAGCTCAAA


 


451
AGCAGCGGCG TATCGTTGCG GCAGGTTTTG GTCAACCGCA GGGGTATTCG


 


501
GTTGTCGGTC TGGTTTATGC TTTCATCTCT TTCGGGCGGG CTGCTGTTTG


 


551
CCGCATCGAC AGACGGTGTG TCGTGGACGA AAGGTTTGGC GATGGCTTCC


 


601
GGCTTCGGTT GGTATTCCCT CTCGGGTTTG GTCATGACCG AGGCTTACGG


 


651
CGCGGTATGG GGCAGCATCA TGCTGCTGAA CGATTTGGCA CGAGAGCTGT


 


701
TTGCACTGGC ATTTATCCCG CTGCTGATGA AGCGTTTTCC AGATGCGGCG


 


751
GTGGGGGTTG GCGGTGCGAC CAGTATGGAT TTTACATTGC CCGTGATTCA


 


801
GGGTGCGGGC GGTTTGGAAG TCGTGCCGGT AGCGGTCAGC TTCGGCGTGG


 


851
TGGTCAATAT CGCCGCCCCG TTTCTGATGG TGGTGTTTTC CGCTTTGGGT


 


901
TGA






This corresponds to the amino acid sequence <SEQ ID 2334; ORF 700>:










m700.pep




1
MDSLMTLLSV LIPMFAGFFI RVPKPYLPAL DKVLSVLVYA VLLLIGVSLS


 


51
RVEDLGSRLD DMALTVLWLF VCTVGANLLA LAVLGKLFPW RIKGKGKGVS


 


101
VGVSGSVGQL GCVLLGFAFG KLMRDIWMPS ESAGMYCLML LVFLIGVQLK


 


151
SSGVSLRQVL VNRRGIRLSV WFMLSSLSGG LLFAASTDGV SWTKGLAMAS


 


201
GFGWYSLSGL VMTEAYGAVW GSIMLLNDLA RELFALAFIP LLMKRFPDAA


 


251
VGVGGATSMD FTLPVIQGAG GLEVVPVAVS FGVVVNIAAP FLMVVFSALG


 


301
*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 700 shows 94.7% identity over a 300 aa overlap with a predicted ORF (ORF700.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2335>:










a700.seq




1
ATGGACAGCC TGATGACGTT GCTTTCGGTA TTGATACCGA TGTTTGCCGG


 


51
ATTTTTTATC CGTGTGCCCA AGCCTTACCT GCCCGCTTTG GATAAGGTGC


 


101
TATCGGTCTT GGTGTATGCT GTGCTGCTGC TGATCGGCGT CTCGTTGTCG


 


151
CGCGTGGAGG ATTTGGGTTC GCGGTTGGAC GATATGGCGT TGACGGTTCT


 


201
GTGGCTGTTT GTTTGTACGG TCGGGGCGAA CCTGCTTGCT TTGGCAGTGT


 


251
TGGGAAAGTT ATTCCCGTGG CGGATAAAGG GGAAAGGGAA GGGCGTTTCG


 


301
GTCGGTGTGT CGGGCAGTGT GGGGCAGCTC GGATGCGTGC TGCTCGGATT


 


351
TGCATCCGGC AAACTGATGC GCGATATTTG GATGCCGTCT GAAAACGCGG


 


401
GTATGTATTG TCTGATGCTG CTGGTGCTCN TCATCGGCGT ACAGCTCAAA


 


451
AGCAGCGGCG TATCGTTGCG GCAGGTTTTG GTCAACCGCA GGGGTATTCG


 


501
GTTGTCGGTC TGGTTTATGC TTTCATCTCT TTCAGGCGGG CTGCTGTTTG


 


551
CCGCATCGGC AGACGGTGTG TCGTGGGTGA AAGGTTTGGC GATGGCTTCC


 


601
GGCTTCGGTT GGTATTCCCT CTCGGGTTTG GTGATGACCG AGGCTTACGG


 


651
CGCGGTATGG GGCAGTATCG CGCTTTTGAA CGATTTGGCA CGAGAGCTGT


 


701
TCGCGCTGGC ATTTATTCCG CTGCTGATGA AGCGTTTTCC CGATGCGGCA


 


751
GTGGGGGTCG GCGGCGCGAC CAGTATGGAT TTCACATTGC CCGTGATTCG


 


801
GGGTGCGGGC GGCTTGGAAG CCGTACCGGT AGCGGTCAGC TTCGGCGTGG


 


851
TGGTCAATAT CGCCGCTCCG TTTCTGATGG TGGTGTTTTC CGCTTTGGGC


 


901
TGA






This corresponds to the amino acid sequence <SEQ ID 2336; ORF 700.a>:










a700.pep




1
MDSLMTLLSV LIPMFAGFFI RVPKPYLPAL DKVLSVLVYA VLLLIGVSLS


 


51
RVEDLGSRLD DMALTVLWLF VCTVGANLLA LAVLGKLFPW RIKGKGKGVS


 


101
VGVSGSVGQL GCVLLGFASG KLMRDIWMPS ENAGMYCLML LVLXIGVQLK


 


151
SSGVSLRQVL VNRRGIRLSV WFMLSSLSGG LLFAASADGV SWVKGLAMAS


 


201
GFGWYSLSGL VMTEAYGAVW GSIALLNDLA RELFALAFIP LLMKRFPDAA


 


251
VGVGGATSMD FTLPVIRGAG GLEAVPVAVS FGVVVNIAAP FLMVVFSALG


 


301
*






m700/a700 97.0% identity in 300 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2337>:










g701.seq




1
ATGTCTTGGC ACATATTCCA AGTTGCAGGG ATACCGACCG CTTCGATGGC


 


51
ACAATCTACG CCGTCTTCGC CGACGATGGC GAAAACTTGT TTGGAGACGT


 


101
CGCCGGAAGC GGGGCTGATG GTATGGGTCG CGCCCAACTC TTTCGCCGGT


 


151
TTCAAACGGT TTTCGTCCAT ATCGCACACG ATAATGGCGG CAGGGCTATA


 


201
CAGTTGGGCG GTCAACAAGG CGGACATACC GACAGGGCCG GCACCTGCGA


 


251
TGAATACGGT ATCGCCGGGT TTCACATCGC CGTATTGCAC GCCGATTTCG


 


301
TGGGCGGTCG GTAAAGCGTC GCTCAACAGC AGGGCGATTT CTTCGTTGAC


 


351
GTTGTCGTGC GGCGGCACGA GGCTGTTGTC GGCATAA






This corresponds to the amino acid sequence <SEQ ID 2338; ORF 701>:










g701.pep




1
MSWHIFQVAG IPTASMAQST PSSPTMAKTC LETSPEAGLM VWVAPNSFAG


 


51
FKRFSSISHT IMAAGLYSWA VNKADIPTGP APAMNTVSPG FTSPYCTPIS


 


101
WAVGKASLNS RAISSLTLSC GGTRLLSA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2339>:










m701.seq




1
ATGTCTTGGC ACATATTCCA TGTAGCAGGG ATACCGACGG CTTCGATGGC


 


51
GCAATCCACG CCGTCTTCGC CGACGATGGC AAAGACTTGT TTGGATACTT


 


101
CGCCGGAAGC AGGGTTAATG GTATGGGTCG CACCCAATTC TTTCGCCAGT


 


151
TTCAAACGGT TTTCGTCCAT ATCGCAAACG ATGATGGCGG CGGGACTGTA


 


201
CAGTTGGGCG GTCAACAGGG CGGACATACC GACAGGGCCT GCCCCAGCGA


 


251
TGAATACGGT GTCGCCGGGT TTGACATCGC CGTATTGCAC GCCGATTTCG


 


301
TGGGCGGTCG GCAAAGCGTC GCTCAACAAC AGGGCGATTT CTTCGTTGAC


 


351
ATTATCGGGC AGCGGAACGA GGCTGTTGTC GGCATAA






This corresponds to the amino acid sequence <SEQ ID 2340; ORF 701>:










m701.pep




1
MSWHIFHVAG IPTASMAQST PSSPTMAKTC LDTSPEAGLM VWVAPNSFAS


 


51
FKRFSSISQT MMAAGLYSWA VNRADIPTGP APAMNTVSPG LTSPYCTPIS


 


101
WAVGKASLNN RAISSLTLSG SGTRLLSA*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 701 shows 92.2% identity over a 128 aa overlap with a predicted ORF (ORF701.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2341>:










a701.seq




1
ATGTCTTGGC ACATATTCCA AGTTGCAGGG ATACCGACGG CTTCGATCGC


 


51
GCAGTCCACG CCGTCTTCGC CGACGATAGC GGCAACTTGC TTGCTTACAT


 


101
CGCCGGAAGC AGGGTTAATG GTATGGGTTG CGCCCAACTC TTTCGCCAGT


 


151
TTCAAACGGT TTTCGTCCAT ATCGCAAACA ATGATGGCGG CGGGGCTGTA


 


201
CAGTTGGGCG GTCGGCAAGG CGGACATACC GACAGGAGCG GCACCTGCGA


 


251
TGAATACGGT GTCGCCGGGT TTGACATCGC CGTATTGCAC GCCGATTTCG


 


301
TGTGCGGTCG GCAAAGCGTC GCTCAACAAC AGGGCGACTT CTTCGTTGAC


 


351
GTTGTCGGGC AGCGGCACGA GGCTGTTGTC GGCATAA






This corresponds to the amino acid sequence <SEQ ID 2342; ORF 701.a>:










a701.pep




1
MSWHIFQVAG IPTASIAQST PSSPTIAATC LLTSPEAGLM VWVAPNSFAS


 


51
FKRFSSISQT MMAAGLYSWA VGKADIPTGA APAMNTVSPG LTSPYCTPIS


 


101
CAVGKASLNN RATSSLTLSG SGTRLLSA*






m701/a701 92.2% identity in 128 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2343>:










g702.seq




1
ATGCCGTGTt ccaAAGCCAG TTGGACTTCG CCCGGAGtgg cAACGCCGGG


 


51
AATCAGGGGA ATGCCGCTGT TGCGGCCGGC TCTGGCGAGG GATTCGTGCA


 


101
AACCCGGGCT GATGGCGAAA ACCGCGCCTG CGTCTTCGAC GGCTTTGAGC


 


151
TGTTCGGGAT TGGTTACCGT ACCTGCGCCG ATGATGGCGT TGGGCATTTC


 


201
TTTGGCAATC AGGCGGATGG CCTCGAGTCC GACGGGGGTG CGCAAGGTAA


 


251
TTTCGAGGGT GGGGATGCCG CCTTCGACAA GGGCGCGGGA CAAATCGACG


 


301
GCGGTGCTTA AGTCGTCAAt cgCCATCACA GGCACAACTG CGCCGGCGGT


 


351
CAGGATTTCG cggggggtca gttga






This corresponds to the amino acid sequence <SEQ ID 2344; ORF 702>:










g702.pep




1
MPCSKASWTS PGVATPGIRG MPLLRPALAR DSCKPGLMAK TAPASSTALS


 


51
CSGLVTVPAP MMALGISLAI RRMASSPTGV RKVISRVGMP PSTRARDKST


 


101
AVLKSSIAIT GTTAPAVRIS RGVS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2345>:










m702.seq




1
ATGCCGTGTT CCAAAGCCAG TTGGATTTCG CCCGGGGTGG CAACACCGGG


 


51
AATCAGGGGG ATGCCGCTGT TGTGGCCGGC TTTGGCGAGG GATTCATGCA


 


101
GCCCCGGGCT GATGGCGAAA ACCGCGCCTG CGTCTTCGAC GGCTTTGAGC


 


151
TGTTCGGGAT TGGTTACCGT ACCTGCGCCG ACGATGGCGT TGGGCACTTC


 


201
TTTGGCAATC AGGCGGATGG CATCGAGGCC GACAGGGGTG CGCAGGGTGA


 


251
TTTCGAGGGT AGGGATGCCG CCTTCGACAA GGGCGTGGGA CAAATCGATG


 


301
GCGGTGCTTA AGTCGTCAAT CGCCATTACC GGCACAACTG CGCCGGCGGT


 


351
CAAAATTTCG CGGGGGGTCA GTTTGGACAT TTCGGTTCTC CGGGTGGAAT


 


401
GGGGTATTTT ATTAAGATGG GACAGGTTGT AG






This corresponds to the amino acid sequence <SEQ ID 2346; ORF 702>:










m702.pep




1
MPCSKASWIS PGVATPGIRG MPLLWPALAR DSCSPGLMAK TAPASSTALS


 


51
CSGLVTVPAP TMALGTSLAI RRMASRPTGV RRVISRVGMP PSTRAWDKSM


 


101
AVLKSSIAIT GTTAPAVKIS RGVSLDISVL RVEWGILLRW DRL*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 702 shows 91.9% identity over a 124 as overlap with a predicted ORF (ORF702.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2347>:










a702.seq




1
ATGCCGTGTT CCAAAGCCAG TTGGATTTCG CCCGGGGTGG CAACACCGGG


 


51
AATCAGGGGG ATGCCGCTGT TGTGGCCGGC TTTGGCGAGG GATTCATGCA


 


101
GCCCCGGGCT GATGGCGAAA ACCGCGCCTG CGTCTTCGAC GGCTTTGAGC


 


151
TGTTCGGGAT TGGTTACCGT ACCTGCGCCG ACGATGGCGT TGGGCACTTC


 


201
TTTGGCAATC AGGCGGATGG CATCGAGGCC GACAGGGGTG CGCAGGGTGA


 


251
TTTCGAGGGT AGGGATGCCG CCTTCGACAA GGGCGTGGGA CAAATCGATG


 


301
GCGGTGCTTA AGTCGTCAAT CGCCATTACC GGCACAACTG CGCCGGCGGT


 


351
CAAAATTTCG CGGGGGGTCA GTTTGGACAT TTCGGTTCTC CGGGTGGAAT


 


401
GGGGTATTTT ATTAAGATGG GACAGGTTGT AG






This corresponds to the amino acid sequence <SEQ ID 2348; ORF 702.a>:










a702.pep




1
MPCSKASWIS PGVATPGIRG MPLLWPALAR DSCSPGLMAK TAPASSTALS


 


51
CSGLVTVPAP TMALGTSLAI RRMASRPTGV RRVISRVGMP PSTRAWDKSM


 


101
AVLKSSIAIT GTTAPAVKIS RGVSLDISVL RVEWGILLRW DRL*






m702/a702 100.0% identity in 143 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2349>:










g703.seq




1
ATGAAAGCAA AAATCCTGAC TTCCGTTGCG CTGCTTGCCT GTTCCGGCAG


 


51
CCTGTTTGCC CAAACGCTGG CAACCGTTAA CGGTCAGAAA ATCGACAGTT


 


101
CCGTCATCGA TGCGCAGGTT GCCGCATTCC GTGCGGAAAA CAGCCGTGCC


 


151
GAAGACACGC CGCAACTGCG CCAATCCCTG CTGGAAAACG AAGTGGTCAA


 


201
CACCGTGGTC GCACAGGAAG TGAAACGCCT GAAACTCGAC CGGTCGGCAG


 


251
AGTTTAAAGA TGCGCTTGCC AAATTGCGTG CCGAAGCGAA AAAGTCGGGC


 


301
GACGACAAGA AACCGTCCTT CAAAACCGTT TGGCAGGCGG TAAAATATGG


 


351
CTTGAACGGC GAGGCATACG CACTGCATAT CGCCAAAACC CAACCGGTTT


 


401
CCGAGCAGGA AGTAAAAGCC GTTTACGACA ATATCAGCGG TTTTTATAAA


 


451
GGCACGCAGG AAGTCCAGTT GGGCGAAATC CTGACCGACA AGGAAGAAAA


 


501
TGCGAAAAAA GCGGTTGCCG ATTTGAAGGC GAAAAAAGGT TTTGATGCCG


 


551
TTTTGAAACA ATACTCGCTC AACGACCGCA CCAAACGGAC CGGCGCGCCG


 


601
GACGGATATG TGCCGCTGAA AGATTTGGAA CAGGGTGTTC CGCCGCTTTA


 


651
TCAGGCAATT AAGGACTTGA AAAAAGGCGA ATTTACGGCA ACGCCGCTGA


 


701
AAAACGGCGA TTTCTACGGC GTTTATTATG TCAACGACAG CCGcgaggTG


 


751
AAAGTGCCTT CTTTTGACGA AATGAAAGGA CAGATTGCCG GCAACCTTCA


 


801
GGCGGAACGG ATTGACCGTG CCGTctgTGc gcTGTTgggt aaggCAAACA


 


851
TCAAACCTGC AAAATAA






This corresponds to the amino acid sequence <SEQ ID 2350; ORF 703>:










g703.pep




1
MKAKILTSVA LLACSGSLFA QTLATVNGQK IDSSVIDAQV AAFRAENSRA


 


51
EDTPQLRQSL LENEVVNTVV AQEVKRLKLD RSAEFKDALA KLRAEAKKSG


 


101
DDKKPSFKTV WQAVKYGLNG EAYALHIAKT QPVSEQEVKA VYDNISGFYK


 


151
GTQEVQLGEI LTDKEENAKK AVADLKAKKG FDAVLKQYSL NDRTKRTGAP


 


201
DGYVPLKDLE QGVPPLYQAI KDLKKGEFTA TPLKNGDFYG VYYVNDSREV


 


251
KVPSFDEMKG QIAGNLQAER IDRAVCALLG KANIKPAK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2351>:










m703.seq




1
ATGAAAGCAA AAATCCTGAC TTCCGTTGCA CTGCTTGCCT GTTCCGGCAG


 


51
CCTGTTTGCC CAAACGCTGG CAACCGTCAA CGGTCAGAAA ATCGACAGTT


 


101
CCGTCATCGA TGCGCAGGTT GCCGCATTCC GTGCGGAAAA CAGCCGTGCC


 


151
GAAGACACGC CGCAACTGCG CCAATCCCTG CTGGAAAACG AAGTGGTCAA


 


201
TACCGTGGTC GCACAGGAAG TGAAACGCCT GAAACTCGAC CGGTCGGCAG


 


251
AGTTTAAAAA TGCGCTTGCC AAATTGCGTG CCGAAGCGAA AAAGTCGGGC


 


301
GACGACAAGA AACCGTCCTT CAAAACCGTT TGGCAGGCGG TAAAATATGG


 


351
CTTGAACGGC GAGGCATACG CATTGCATAT CGCCAAAACC CAACCGGTTT


 


401
CCGAGCAGGA AGTAAAAGCC GCATATGACA ATATCAGCGG TTTTTACAAA


 


451
GGTACGCAGG AAGTCCAGTT GGGCGAAATC CTGACCGACA AGGAAGAAAA


 


501
TGCAAAAAAA GCGGTTGCCG ACTTGAAGGC GAAAAAAGGT TTCGATGCCG


 


551
TCTTGAAACA ATATTCCCTC AACGACCGTA CCAAACAGAC CGGTGCGCCG


 


601
GTCGGATATG TGCCGCTGAA AGATTTGGAA CAGGGTGTTC CGCCGCTTTA


 


651
TCAGGCAATT AAGGACTTGA AAAAAGGCGA ATTTACGGCA ACGCCGCTGA


 


701
AAAACGGCGA TTTCTACGGC GTTTATTATG TCAACGACAG CCGCGAGGTA


 


751
AAAGTGCCTT CTTTTGATGA AATGAAAGGA CAGATTGCGG GCAACCTTCA


 


801
GGCGGAACGG ATTGACCGTG CCGTCGGTGC ACTGTTGGGC AAGGCAAACA


 


851
TCAAACCTGC AAAATAA






This corresponds to the amino acid sequence <SEQ ID 2352; ORF 703>:










m703.pep




1
MKAKILTSVA LLACSGSLFA QTLATVNGQK IDSSVIDAQV AAFRAENSRA


 


51
EDTPQLRQSL LENEVVNTVV AQEVKRLKLD RSAEFKNALA KLRAEAKKSG


 


101
DDKKPSFKTV WQAVKYGLNG EAYALHIAKT QPVSEQEVKA AYDNISGFYK


 


151
GTQEVQLGEI LTDKEENAKK AVADLKAKKG FDAVLKQYSL NDRTKQTGAP


 


201
VGYVPLKDLE QGVPPLYQAI KDLKKGEFTA TPLKNGDFYG VYYVNDSREV


 


251
KVPSFDEMKG QIAGNLQAER IDRAVGALLG KANIKPAK*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 703 shows 98.3% identity over a 288 aa overlap with a predicted ORF (ORF703.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2353>:










a703.seq




1
ATGAAAGCAA AAATCCTGAC TTCCGTTGCA CTGCTTGCCT GTTCCGGCAG


 


51
CCTGTTTGCC CAAACGCTGG CAACCGTCAA CGGTCAGAAA ATCGACAGTT


 


101
CCGTCATTGA TGCGCAGGTT GCCGCATTCC GTGCGGAAAA CAGCCGTGCC


 


151
GAAGACACGC CGCAACTGCG CCAATCCCTG CTGGAAAACG AAGTGGTCAA


 


201
CACCGTGGTC GCACAGGAAG TGAAACGCCT GAAACTCGAC CGGTCGGCAG


 


251
AGTTTAAAAA TGCGCTTGCC AAATTGCGTG CCGAAGCGAA AAAGTCGGGC


 


301
GACGACAAGA AACCGTCCTT CAAAACCGTT TGGCAGGCGG TAAAATATGG


 


351
CTTGAACGGC GAGGCATACG CGCTGCATAT CGCCAAAACC CAACCGGTTT


 


401
CCGAGCAGGA AGTAAAAGCC GCATATGACA ATATCAGCGG TTTTTACAAA


 


451
GGTACGCAGG AAGTCCAGTT GGGCGAAATC CTGACCGACA AGGAAGAAAA


 


501
TGCAAAAAAA GCGGTTGCCG ACTTGAAGGC GAAAAAAGGT TTCGATGCCG


 


551
TCTTGAAACA ATATTCCCTC AACGACCGTA CCAAACAGAC CGGTGCGCCG


 


601
GTCGGATATG TGCCGCTGAA AGATTTGGAA CAGGGTGTTC CGCCGCTTTA


 


651
TCAGGCAATT AAGGACTTGA AAAAAGGCGA ATTTACGGCA ACGCCGCTGA


 


701
AAAACGGCGA TTTCTACGGC GTTTATTATG TCAACGACAG CCGCGAGGTA


 


751
AAAGTGCCTT CTTTTGATGA AATGAAAGGA CAGATTGCGG GCAACCTTCA


 


801
GGCGGAACGG ATTGACCGTG CCGTCGGTGC ACTGTTGGGC AAGGCAAACA


 


851
TCAAACCTGC AAAATAA






This corresponds to the amino acid sequence <SEQ ID 2354; ORF 703.a>:










a703.pep




1
MKAKILTSVA LLACSGSLFA QTLATVNGQK IDSSVIDAQV AAFRAENSRA


 


51
EDTPQLRQSL LENEVVNTVV AQEVKRLKLD RSAEFKNALA KLRAEAKKSG


 


101
DDKKPSFKTV WQAVKYGLNG EAYALHIAKT QPVSEQEVKA AYDNISGFYK


 


151
GTQEVQLGEI LTDKEENAKK AVADLKAKKG FDAVLKQYSL NDRTKQTGAP


 


201
VGYVPLKDLE QGVPPLYQAI KDLKKGEFTA TPLKNGDFYG VYYVNDSREV


 


251
KVPSFDEMKG QIAGNLQAER IDRAVGALLG KANIKPAK*






m703/a703 100.0% identity in 288 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2355>:










a704.seq




1
ATGAAAAAAA CCTGTTTCCA CTGCGGGCTG GACGTTCCCG AAAACCTGCA


 


51
TCTGACCGTC CGTTACGAAA ACGAAGACCG CGAAACCTGC TGCGCCGGTT


 


101
GTCAGGCAGT CGCACAAAGC ATTATTGACG CGGGCTTGGG CAGTTATTAC


 


151
AAACAACGCA CCGCCGACGC GCAAAAAACC GAGCTGCCGC CCCAAGAAAT


 


201
CCTCGACCAA ATCCGCCTGT ACGACCTGCC CGAAGTCCAG TCCGACTTTG


 


251
TGGAAACCCA CGGCGGCACG CGCGAGGCGG TTTTAATGCT CGGCGGCATC


 


301
ACCTGCGCCG CCTGCGTCTG GCTGATCGAA CAGCAGCTTT TGCGTACAGA


 


351
CGGCATCGTC CGCATCGACC TCAATTACAG CACGCACCGC TGCCGCGTCG


 


401
TCTGGGACGA CGGCAAAATC CGCCTTTCCG ACATTCTGTT GAAAATCAGG


 


451
CAGATAGGCT ACACCGCCGC ACCCTATGAC GCGCAAAAAA TCGAAGCCGC


 


501
CAACCAAAAA GAACGCAAAC AATACATCGT CCGCCTCGCC GTTGCCGGGC


 


551
TGGGGATGAT GCAGACGATG ATGTTCGCGC TGCCGACCTA CCTTTACGGC


 


601
GGCGACATCG AACCCGATTT CCTGCAAATC CTCCATTGGG GCGGCTTTTT


 


651
AATGGTGCTG CCCGTCGTAT TCTATTGCGC CGTCCCGTTT TATCAAGGCG


 


701
CGCTGCGCGA CTTGAAAAAC CGCCGCGTCG GCATGGATAC GCCGATTACC


 


751
GTCGCCATCA TCATGACCTT TATCGCCGGC GTTTACAGCC TTGCGACAAA


 


801
TGCGGGGCAG GGGATGTATT TCGAATCCAT CGCGATGCTG CTGTTTTTCC


 


851
TGCTGGGCGG ACGCTTTATG GAACACATTG CCCGCCGTAA GGCAGGCGAT


 


901
GCCGCCGAGA GGCTGGTGAA GCTGATTCCT GCGTTTTGCC ATCATATGCC


 


951
CGATTACCCC GATACGCAGG AAACCTGCGA GGCAGCTGTC GTCAAATTGA


 


1001
AGGCGGGCGA TATCGTGCTG GTCAAACCGG GCGAAACCAT CCCCGTTGAC


 


1051
GGCACGGTGC TGGAAGGAAG CAGTGCCGTC AACGAATCTA TGCTGACCGG


 


1101
CGAGAGCCTG CCCGTCGCCA AAATGCCGTC TGAAAAAGTA ACCGCCGGCA


 


1151
CACTCAACAC GCAAAGCCCC CTGATTATAC GCACCGACCG CACCGGCGGC


 


1201
GGCACGCGAC TGTCGCACAT CGTCCGCCTG CTCGACCGCG CCTTAGCGCA


 


1251
AAAACCGCGC ACTGCCGAGT TGGCGGAACA ATACGCCTCG TCTTTCATAT


 


1301
TCGGCGAACT CCTGCTTGCC GTCCCCGTCT TCATCGGCTG GACGCTGTAC


 


1351
GCCGACGCGC ACACCGCATT GTGGATTACC GTCGCCCTGC TGGTCATTAC


 


1401
CTGCCCCTGC GCCTTATCGC TTGCCACGCC GACCGCGCTG GCAGCTTCTA


 


1451
CCGGTACGCT GGCGCGCGAA GGTATTTTAA TCGGCGGAAA GCAGGCAATC


 


1501
GAAACCCTCG CCCAAACCAC CGACATCATC TTCGACAAAA CCGGCACGCT


 


1551
GACCCAAGGC AAACCCGCCG TCCGCCGTAT CTCATTGTTG AGAGGCACAG


 


1601
ACGAAGCCTT TGTTCTCGCG GTGGCGCAGG CTTTAGAACA ACAGTCCGAA


 


1651
CATCCCCTTG CCCGCGCCAT CCTCAACTGC CGCATTTCAG ACGGCAGCGT


 


1701
CCCCGACATC GCTATTAAAC AACGCCTCAA CCGCATCGGC GAAGGCGTGG


 


1751
GCGCGCAACT GACCGTCAAC GGCGAAACAC AGGTTTGGGC ATTGGGCAGG


 


1801
GCATCCTATG TCGCCGAAAT TTCAGGTAAA GAACCGCAAA CAGAAGGCGG


 


1851
CGGCAGCGCG GTTTACCTCG GCAGTCAAAG CGGTTTCCAA GCCGTGTTCT


 


1901
ACCTGCAAGA CCCGCTCAAA GACAGCGCGG CGGAGGCGGT GCGGCAGTTG


 


1951
GCAGGCAAAA ACCTGACGCT GCACATTCTC AGCGGCGACC GTGAAACCGC


 


2001
CGTTGCCGAA ACCGCACGCG CCCTGGGTGT CGCGCACTAC CGCGCCCAAG


 


2051
CCATGCCCGA GGACAAACTG GAATACGTCA AAGCCTTGCA AAAAGAAGGG


 


2101
AAAAAAGTGC TGATGATAGG CGACGGCATC AACGACGCGC CCGTTTTGGC


 


2151
GCAGGCAGAC GTATCCGCCG CCGCAGCGGG CGGGACGGAT ATTGCGAGGG


 


2201
ACGGCGCGGA CATTGTGTTA TTGAACGAAG ATTTGCGTAC CGTCGCCCAC


 


2251
CTGCTCGATC AGGCGCGGCG CACCCGCCAT ATTATCCGGC AAAACCTGAT


 


2301
ATGGGCGGGC GCGTACAATA TCATTGCCGT ACCGCTTGCC GTTTTGGGCT


 


2351
ATGTCCAACC GTGGATAGCC GCACTGGGTA TGAGCTTCAG TTCGCTGGCG


 


2401
GTTTTGGGCA ACGCCCTGCG CCTTCACAAA CGGGGGAAAA TGCAGTCTGA


 


2451
AAAAATGCCG TCCGAACAAT GA






This corresponds to the amino acid sequence <SEQ ID 2356; ORF 703>:










a704.pep




1
MKKTCFHCGL DVPENLHLTV RYENEDRETC CAGCQAVAQS IIDAGLGSYY


 


51
KQRTADAQKT ELPPQEILDQ IRLYDLPEVQ SDFVETHGGT REAVLMLGGI


 


101
TCAACVWLIE QQLLRTDGIV RIDLNYSTHR CRVVWDDGKI RLSDILLKIR


 


151
QIGYTAAPYD AQKIEAANQK ERKQYIVRLA VAGLGMMQTM MFALPTYLYG


 


201
GDIEPDFLQI LHWGGFLMVL PVVFYCAVPF YQGALRDLKN RRVGMDTPIT


 


251
VAIIMTFIAG VYSLATNAGQ GMYFESIAML LFFLLGGRFM EHIARRKAGD


 


301
AAERLVKLIP AFCHHMPDYP DTQETCEAAV VKLKAGDIVL VKPGETIPVD


 


351
GTVLEGSSAV NESMLTGESL PVAKMPSEKV TAGTLNTQSP LIIRTDRTGG


 


401
GTRLSHIVRL LDRALAQKPR TAELAEQYAS SFIFGELLLA VPVFIGWTLY


 


451
ADAHTALWIT VALLVITCPC ALSLATPTAL AASTGTLARE GILIGGKQAI


 


501
ETLAQTTDII FDKTGTLTQG KPAVRRISLL RGTDEAFVLA VAQALEQQSE


 


551
HPLARAILNC RISDGSVPDI AIKQRLNRIG EGVGAQLTVN GETQVWALGR


 


601
ASYVAEISGK EPQTEGGGSA VYLGSQSGFQ AVFYLQDPLK DSAAEAVRQL


 


651
AGKNLTLHIL SGDRETAVAE TARALGVAHY RAQAMPEDKL EYVKALQKEG


 


701
KKVLMIGDGI NDAPVLAQAD VSAAAAGGTD IARDGADIVL LNEDLRTVAH


 


751
LLDQARRTRH IIRQNLIWAG AYNIIAVPLA VLGYVQPWIA ALGMSFSSLA


 


801
VLGNALRLHK RGKMQSEKMP SEQ*






m704/a704 99.8% identity in 823 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2357>:










g705.seq




1
GTGTTCAATA ATTTCCttgC CTCTCTGCCG TTTATGACGG AAACACGCGC


 


51
TGATATGCTC ATCAGCGCGT TTTGGCCCAT GGTTAAAGCC GGCTTTACAG


 


101
TGTCTTtgcC TTTGGCGATC GCTTCTTTCG TTATCGGCAT GATTATTGCC


 


151
GTAGCCGTTG CTTTGGTAAG AATCATGCCT TCCGGCGGTA TTTTCCAAAA


 


201
ATGCTTGTTG AAGCTGGTGG AATTTTATAT TTCCGTCGTT CGCGGTACGC


 


251
CGCTGTTGGT TCAGCTTGTG ATTGTGTTTT ACGGGCTGCC GTCCGTCGGC


 


301
ATCTATATCA ATCCGATTCC CGCCGCCATC ATCGGCTTTT CGCTCAATGT


 


351
CGGCGCATAC GCTTCCGAAA CCATACGCGC GGCGATTTTG TCCGTGCCGA


 


401
AAGGGCAGTG GGAAGCAGGT TTCTCCATCG GTATGACCTA TATGCAGACG


 


451
TTCCGCCGCA TCGTCGCACC GCAGGCATTC CGCGTCGCCG TTCCGCCGTT


 


501
GAGCAACGAG TTTATCGGCT TGTTCAAAAA CACCTCGCTT GCCGCCGTGG


 


551
TAACGGTAAC GGAGCTTTTC CGTGTCGCAC AGGAAACGGC AAACCGCACT


 


601
TATGACTTTT TGCCTGTCTA TATCGAAGCT GCATTGGTTT ATTGGTGTTT


 


651
CTGTAAAGTG CTGTTTTTGA TTCAGGCGCG TTTGGAAAAA CGTTTCGACC


 


701
GTTATGTCGC CAAATAA






This corresponds to the amino acid sequence <SEQ ID 2358; ORF 705>:










g705.pep




1
VFNNFLASLP FMTETRADML ISAFWPMVKA GFTVSLPLAI ASFVIGMIIA


 


51
VAVALVRIMP SGGIFQKCLL KLVEFYISVV RGTPLLVQLV IVFYGLPSVG


 


101
IYINPIPAAI IGFSLNVGAY ASETIRAAIL SVPKGQWEAG FSIGMTYMQT


 


151
FRRIVAPQAF RVAVPPLSNE FIGLFKNTSL AAVVTVTELF RVAQETANRT


 


201
YDFLPVYIEA ALVYWCFCKV LFLIQARLEK RFDRYVAK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2359>:










m705.seq




1
GTGTTCAATA ATTTCCTTGC TTCGCTGCCG TTTATGACGG AAACACGCGC


 


51
CGATATGATT GTCAGCGCGT TTTTGCCTAT GGTCAAAGCC GGCTTCGCGG


 


101
TCTCTCTGCC TTTGGCGGCA GCTTCTTTCG TTATCGGTAT GATGATTGCG


 


151
GTAGCCGTGG CTTTGGTGCG GATTATGCCC GCCGGCGGCA TCGTGCGGAA


 


201
AATCCTGCTG AAATTGGTGG AATTTTATAT TTCCGTCATT CGCGGTACGC


 


251
CGCTGTTGGT TCAGCTTGTG ATTGTGTTTT ACGGGCTGCC TTCCGTCGGC


 


301
ATCTATATCG ACCCGATTCC TGCCGCCATC ATCGGCTTTT CGCTCAATGT


 


351
CGGCGCATAC GCTTCCGAAA CCATACGCGC GGCAATTTTG TCCGTACCTA


 


401
AAGGCCAATG GGAAGCAGGT TTCTCCATCG GCATGACCTA TATGCAGACG


 


451
TTCCGCCGCA TTGTCGCGCC GCAGGCATTC CGCGTTGCCG TGCCGCCTTT


 


501
GAGCAACGAG TTTATCGGTT TGTTTAAAAA CACCTCGCTC GCGGCAGTCG


 


551
TGACGGTAAC GGAATTATTC CGCGTCGCGC AGGAAACGGC AAACCGCACT


 


601
TATGACTTTT TGCCCGTCTA TATCGAAGCC GCTTTGGTTT ACTGGTGTTT


 


651
TTGTAAAGTG CTGTTCCTGA TTCAGGCGCG TTTGGAAAAA CGTTTCGACC


 


701
GCTACGTCGC CAAATAA






This corresponds to the amino acid sequence <SEQ ID 2360; ORF 705>:










m705.pep




1
VFNNFLASLP FMTETRADMI VSAFLPMVKA GFAVSLPLAA ASFVIGMMIA


 


51
VAVALVRIMP AGGIVRKILL KLVEFYISVI RGTPLLVQLV IVFYGLPSVG


 


101
IYIDPIPAAI IGFSLNVGAY ASETIRAAIL SVPKGQWEAG FSIGMTYMQT


 


151
FRRIVAPQAF RVAVPPLSNE FIGLFKNTSL AAVVTVTELF RVAQETANRT


 


201
YDFLPVYIEA ALVYWCFCKV LFLIQARLEK RFDRYVAK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 705 shows 95.0% identity over a 238 aa overlap with a predicted ORF (ORF 705) from N. gonorrhoeae: 

m705/g705 95.0% identity in 238 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2361>:










a705.seq




1
GTGTTCAATA ATTTCCTTGC TTCGCTGCCG TTTATGACGG AAACACGCGC


 


51
CGATATGATT GTCAGCGCGT TTTTGCCTAT GGTCAAAGCC GGCTTCGCGG


 


101
TCTCTCTGCC TTTGGCGGCA GCTTCTTTCG TTATCGGTAT GATGATTGCG


 


151
GTAGCCGTGG CTTTGGTGCG GATTATGCCC GCCGGCGGCA TCGTGCGGAA


 


201
AATCCTGCTG AAATTGGTGG AATTTTATAT TTCCGTCATT CGCGGTACGC


 


251
CGCTGTTGGT TCAGCTTGTG ATTGTGTTTT ACGGGCTGCC TTCCGTCGGC


 


301
ATCTATATCG ACCCGATTCC TGCCGCCATC ATCGGCTTTT CGCTCAATGT


 


351
CGGCGCATAT GCTTCCGAAA CCATACGCGC GGCAATTTTG TCCGTACCGA


 


401
AAGGCCAATG GGAAGCAGGT TTCTCCATCG GCATGACCTA TATGCAGACG


 


451
TTCCGCCGCA TCGTCGCGCC GCAGGCATTT CGCGTTGCCG TGCCGCCTTT


 


501
GAGCAACGAG TTTATCGGTT TGTTTAAAAA CACCTCGCTC GCGGCAGTCG


 


551
TGACGGTAAC GGAATTATTC CGCGTCGCGC AGGAAACGGC AAACCGCACT


 


601
TATGACTTTT TGCCCGTCTA TATCGAAGCC GCTTTGGTTT ACTGGTGTTT


 


651
TTGTAAAGTG CTGTTCCTGA TTCAGGCGCG TTTGGAAAAA CGTTTCGACC


 


701
GCTACGTCGC CAAATAA






This corresponds to the amino acid sequence <SEQ ID 2362; ORF 705.a>:










a705.pep




1
VFNNFLASLP FMTETRADMI VSAFLPMVKA GFAVSLPLAA ASFVIGMMIA


 


51
VAVALVRIMP AGGIVRKILL KLVEFYISVI RGTPLLVQLV IVFYGLPSVG


 


101
IYIDPIPAAI IGFSLNVGAY ASETIRAAIL SVPKGQWEAG FSIGMTYMQT


 


151
FRRIVAPQAF RVAVPPLSNE FIGLFKNTSL AAVVTVTELF RVAQETANRT


 


201
YDFLPVYIEA ALVYWCFCKV LFLIQARLEK RFDRYVAK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 705 shows 100.0% identity over a 238 aa overlap with a predicted ORF (ORF 705) from N. meningitidis: 

a705/m705 100.0% identity in 238 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2363>:










g706.seq




1
ATGAACTCCT CGCAACGCAA ACGCCTTTCC GgccGCTGGC TCAACTCCTA


 


51
CGAACGCTac cGCCaccGCC GCCTCATACA TGCCGTGCGG CTCGGCggaa


 


101
ccgtCCTGTT CGCCACCGCA CTCGCCCGgc tACTCCACCT CCAacacggc


 


151
gAATGGATAG GGAtgaCCGT CTTCGTCGTC CTCGGCATGC TCCAGTTCCA


 


201
AGGCgcgatt tActccaacg cggtgGAacg taTGctcggt acggtcatcg


 


251
ggctgGGCGC GGGTTTGGgc gTTTTATGGC TGAACCAGCA TTAtttccac


 


301
ggcaacCTcc tcttctacct gaccatcggc acggcaagcg cactggccgg


 


351
ctGGGCGGCG GTCGGCAAAA acggctacgt ccctatgctg GCGGGGctgA


 


401
CGATGTGCAT gctcatcggc gACAACGGCA GCGAATGGCT CGACAGCGGC


 


451
CTGATGCGCG CGATGAACGT CCTCATCGGC GCCGCCATCG CCATTGCCGC


 


501
CGCCAAACTG CTGCCGCTGA AATCCACACT GATGTGGCGT TTCATGCTTG


 


551
CCGACAACCT GGCCGACTGC AGCAAAATGA TTGCCGAAAT CAGCAACGGC


 


601
AGGCGTATGA CGCGCGAACG TTTGGAGCAG AATATGGTCA AAATGCGCCA


 


651
AATCAACGCA CGCATGGTCA AAAGCCGCAG CCACCTCGCC GCCACATCGG


 


701
GCGAAAGCCG CATCAGCCCC TCCATGATGG AAGCCATGCA GCACGCCCAC


 


751
CGCAAAATCG TCAACACCAC CGAGCTGCTC CTGACCACCG CCGCCAAGCT


 


801
GCAATCTCCC AAACTCAACG GCAGCGAAAT CCGGCTGCTC GACCGCCACT


 


851
TCACACTGCT CCAAACCGAC CTGCAACAAA CCGCCGCCCT CATCAACGGC


 


901
AGACACGCCC GCCGCATCCG CATCGACACC GCCATCAACC CCGAACTGGA


 


951
AGCCCTCGCC GAACACCTCC ACTACCAATG GCAGGGCTTC CTCTGGCTCA


 


1001
GCACCAATAT GCGTCAGGAA ATTTCCGCCC TCGTCATCCT GCTGCAACGC


 


1051
ACCCGCCGCA AATGGCTGGA TGCCCACGAA CGCCAACACC TGCGCCAAAG


 


1101
CCTGCTTGAA ACACGGGAAC ACGGCTGA






This corresponds to the amino acid sequence <SEQ ID 2364; ORF 706.ng>:










g706.pep




1
MNSSQRKRLS GRWLNSYERY RHRRLIHAVR LGGTVLFATA LARLLHLQHG


 


51
EWIGMTVFVV LGMLQFQGAI YSNAVERMLG TVIGLGAGLG VLWLNQHYFH


 


101
GNLLFYLTIG TASALAGWAA VGKNGYVPML AGLTMCMLIG DNGSEWLDSG


 


151
LMRAMNVLIG AAIAIAAAKL LPLKSTLMWR FMLADNLADC SKMIAEISNG


 


201
RRMTRERLEQ NMVKMRQINA RMVKSRSHLA ATSGESRISP SMMEAMQHAH


 


251
RKIVNTTELL LTTAAKLQSP KLNGSEIRLL DRHFTLLQTD LQQTAALING


 


301
RHARRIRIDT AINPELEALA EHLHYQWQGF LWLSTNMRQE ISALVILLQR


 


351
TRRKWLDAHE RQHLRQSLLE TREHG*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2365>:










m706.seq




1
ATGAACACCT CGCAACGCAA CCGCCTCGTC AGCCGCTGGC TCAACTCCTA


 


51
CGAACGCTAC CGCTACCGCC GCCTCATCCA CGCCGTCCGG CTCGGCGGGG


 


101
CCGTCCTGTT CGCCACCGCC TCCGCCCGGC TGCTCCACCT CCAACACGGC


 


151
GAGTGGATAG GGATGACCGT CTTCGTCGTC CTCGGCATGC TCCAGTTTCA


 


201
AGGGGCGATT TACTCCAAGG CGGTGGAACG TATGCTCGGC ACGGTCATCG


 


251
GGCTGGGCGC GGGTTTGGGC GTTTTATGGC TGAACCAGCA TTATTTCCAC


 


301
GGCAACCTCC TCTTCTACCT CACCGTCGGC ACGGCAAGCG CACTGGCCGG


 


351
CTGGGCGGCG GTCGGCAAAA ACGGCTACGT CCCTATGCTG GCAGGGCTGA


 


401
CGATGTGTAT GCTCATCGGC GACAACGGCA GCGAATGGCT CGACAGCGGA


 


451
CTCATGCGCG CCATGAACGT CCTCATCGGC GCGGCCATCG CCATCGCCGC


 


501
CGCCAAACTG CTGCCGCTGA AATCCACACT GATGTGGCGT TTCATGCTTG


 


551
CCGACAACCT GGCCGACTGC AGCAAAATGA TTGCCGAAAT CAGCAACGGC


 


601
AGGCGCATGA CCCGCGAACG CCTCGAGGAG AACATGGCGA AAATGCGCCA


 


651
AATCAACGCA CGCATGGTCA AAAGCCGCAG CCATCTCGCC GCCACATCGG


 


701
GCGAAAGCCG CATCAGCCCC GCCATGATGG AAGCCATGCA GCACGCCCAC


 


751
CGTAAAATCG TCAACACCAC CGAGCTGCTC CTGACCACCG CCGCCAAGCT


 


801
GCAATCTCCC AAACTCAACG GCAGCGAAAT CCGGCTGCTT GACCGCCACT


 


851
TCACACTGCT CCAAACCGAC CTGCAACAAA CCGTCGCCCT TATCAACGGC


 


901
AGACACGCCC GCCGCATCCG CATCGACACC GCCATCAACC CCGAACTGGA


 


951
AGCCCTCGCC GAACACCTCC ACTACCAATG GCAGGGCTTC CTCTGGCTCA


 


1001
GCACCAATAT GCGTCAGGAA ATTTCCGCCC TCGTCATCCT GCTGCAACGC


 


1051
ACCCGCCGCA AATGGCTGGA TGCCCACGAA CGCCAACACC TGCGCCAAAG


 


1101
CCTGCTTGAA ACACGGGAAC ACGGCTGA






This corresponds to the amino acid sequence <SEQ ID 2366; ORF 706>:










m706.pep




1
MNTSQRNRLV SRWLNSYERY RYRRLIHAVR LGGAVLFATA SARLLHLQHG


 


51
EWIGMTVFVV LGMLQFQGAI YSKAVERMLG TVIGLGAGLG VLWLNQHYFH


 


101
GNLLFYLTVG TASALAGWAA VGKNGYVPML AGLTMCMLIG DNGSEWLDSG


 


151
LMRAMNVLIG AAIAIAAAKL LPLKSTLMWR FMLADNLADC SKMIAEISNG


 


201
RRMTRERLEE NMAKMRQINA RMVKSRSHLA ATSGESRISP AMMEAMQHAH


 


251
RKIVNTTELL LTTAAKLQSP KLNGSEIRLL DRHFTLLQTD LQQTVALING


 


301
RHARRIRIDT AINPELEALA EHLHYQWQGF LWLSTNMRQE ISALVILLQR


 


351
TRRKWLDAHE RQHLRQSLLE TREHG*






m706/g706 96.5% identity in 375 aa overlap





The following partial DNA sequence was identified in N. meningitides <SEQ ID 2367>:










a706.seq




1
ATGAACACCT CGCAACGCAA CCGCCTCGTC AGCCGCTGGC TCAACTCCTA


 


51
CGAACGCTAC CGCTACCGCC GCCTCATCCA CGCCGTCCGG CTCGGCGGGG


 


101
CCGTCCTGTT CGCCACCGCC TCCGCCCGGC TGCTCCACCT CCAACACGGC


 


151
GAGTGGATAG GGATGACCGT CTTCGTCGTC CTCGGCATGC TCCAGTTTCA


 


201
AGGGGCGATT TACTCCAAGG CGGTGGAACG TATGCTCGGC ACGGTCATCG


 


251
GGCTGGGCGC GGGTTTGGGC GTTTTATGGC TGAACCAGCA TTATTTCCAC


 


301
GGCAACCTCC TCTTCTACCT CACCGTCGGC ACGGCAAGCG CACTGGCCGG


 


351
CTGGGCGGCG GTCGGCAAAA ACGGCTACGT CCCTATGCTG GCGGGGCTGA


 


401
CGATGTGCAT GCTCATCGGC GACAACGGCA GCGAATGGTT CGACAGCGGC


 


451
CTGATGCGCG CGATGAACGT CCTCATCGGC GCGGCCATCG CCATCGCCGC


 


501
CGCCAAACTG CTGCCGCTGA AATCCACACT GATGTGGCGT TTCATGCTTG


 


551
CCGACAACCT GACCGACTGC AGCAAAATGA TTGCCGAAAT CAGCAACGGC


 


601
AGGCGCATGA CCCGCGAACG CCTCGAAGAG AACATGGCGA AAATGCGCCA


 


651
AATCAACGCA CGCATGGTCA AAAGCCGCAG CCACCTCGCC GCCACATCGG


 


701
GCGAAAGCCG CATCAGCCCC GCCATGATGG AAGCCATGCA GCACGCCCAC


 


751
CGTAAAATTG TCAACACCAC CGAGCTGCTC CTGACCACCG CCGCCAAGCT


 


801
GCAATCTCCC AAACTCAACG GCAGCGAAAT CCGGCTGCTT GACCGCCACT


 


851
TCACACTGCT CCAAACCGAC CTGCAACAAA CCGTCGCCCT TATCAACGGC


 


901
AGACACGCCC GCCGCATCCG CATCGACACC GCCATCAACC CCGAACTGGA


 


951
AGCCCTCGCC GAACACCTCC ACTACCAATG GCAGGGCTTC CTCTGGCTCA


 


1001
GCACCAATAT GCGTCAGGAA ATTTCCGCCC TCGTCATCCT GCTGCAACGC


 


1051
ACCCGCCGCA AATGGCTGGA TGCCCACGAA CGCCAACACC TGCGCCAAAG


 


1101
CCTGCTTGAA ACACGGGAAC ACAGTTGA






This corresponds to the amino acid sequence <SEQ ID 2368; ORF 706.a>:










a706.pep




1
MNTSQRNRLV SRWLNSYERY RYRRLIHAVR LGGAVLFATA SARLLHLQHG


 


51
EWIGMTVFVV LGMLQFQGAI YSKAVERMLG TVIGLGAGLG VLWLNQHYFH


 


101
GNLLFYLTVG TASALAGWAA VGKNGYVPML AGLTMCMLIG DNGSEWFDSG


 


151
LMRAMNVLIG AAIAIAAAKL LPLKSTLMWR FMLADNLTDC SKMIAEISNG


 


201
RRMTRERLEE NMAKMRQINA RMVKSRSHLA ATSGESRISP AMMEAMQHAH


 


251
RKIVNTTELL LTTAAKLQSP KLNGSEIRLL DRHFTLLQTD LQQTVALING


 


301
RHARRIRIDT AINPELEALA EHLHYQWQGF LWLSTNMRQE ISALVILLQR


 


351
TRRKWLDAHE RQHLRQSLLE TREHS*






a706/m706 99.5% identity in 374 aa overlap





g707.seq not found

g707.pep not found

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2369>:










m707.seq




1
ATGGAAATTA TTAACGATGC AGAACTTATC CGTTCCATGC AGCGTCAGCA


 


51
GCACATAGAT GCTGAATTGT TAACTGATGC AAATGTCCGT TTCGAGCAAC


 


101
CATTGGAGAA GAACAATTAT GTCCTGAGTG AAGATGAAAC ACCGTGTACT


 


151
CGGGTAAATT ACATTAGTTT AGATGATAAG ACGGTGCGCA AATTTTCTTT


 


201
TCTTCCTTCT GTGCTCATGA AAGAAACAGC TTTTAAAACT GGGATGTGTT


 


251
TAGGTTCCAA TAATTTGAGC AGGCTACAAA AAGCCGCGCA ACAGATACTG


 


301
ATCGTGCGTG GCTACCTCAC TTCCCAAGCT ATTATCCAAC CACAGAATAT


 


351
GGATTCGGGA ATTCTGAAAT TACGGGTATC AGCAGGCGAA ATAGGGGATA


 


401
TCCGCTATGA AGAAAAACGG GATGGGAAGT CTGCCGAGGG CAGTATTAGT


 


451
GCATTCAATA ACAAATTTCC CTTATATAGG AACAAAATTC TCAATCTTCG


 


501
CGATGTAGAG CAGGGCTTGG AAAACCTGCG TCGTTTGCCG AGTGTTAAAA


 


551
CAGATATTCA GATTATACCG TCCGAAGAAG AAGGCAAAAG CGATTTACAG


 


601
ATCAAATGGC AGCAGAATAA ACCCATACGG TTCAGTATCG GTATAGATGA


 


651
TGCGGGCGGC AAAACGACCG GCAAATATCA AGGAAATGTC GCTTTATCGT


 


701
TCGATAACCC TTTGGGCTTA AGCGATTTGT TTTATGTTTC ATATGGACGC


 


751
GGTTTGGCGC ACAAAACGGA CTTGACTGAT GCCACCGGTA CGGAAACTGA


 


801
AAGCGGATCC AGAAGTTACA GCGTGCATTA TTCGGTGCCC GTAAAAAAAT


 


851
GGCTGTTTTC TTTTAATCAC AATGGACATC GTTACCACGA AGCAACCGAA


 


901
GGCTATTCCG TCAATTACGA TTACAACGGC AAACAATATC AGAGCAGCCT


 


951
GGCCGCCGAG CGCATGCTTT GGCGTAACAG ACTTCATAAA ACTTCAGTCG


 


1001
GAATGAAATT ATGGACACGC CAAACCTATA AATACATCGA CGATGCCGAA


 


1051
ATCGAAGTAC AACGCCGCCG CTCTGCAGGC TGGGAAGCCG AATTGCGCCA


 


1101
CCGTGCTTAC CTCAACCGTT GGCAGCTTGA CGGCAAGTTG TCTTACAAAC


 


1151
GCGGGACCGG CATGCGCCAA AGTATGCCTG CACCGGAAGA AAACGGCGGC


 


1201
GATATTCTTC CAGGTACATC TCGTATGAAA ATCATTACTG CCAGTTTGGA


 


1251
CGCAGCCGCC CCATTTATTT TAGGCAAACA GCAGTTTTTC TACGCAACCG


 


1301
CCATTCAAGC TCAATGGAAC AAAACGCCGT TGGTTGCCCA AGATAAATTG


 


1351
TCAATCGGCA GCCGCTACAC CGTTCGCGGA TTTGATGGGG AGCAGAGTCT


 


1401
TTTCGGAGAG CGAGGTTTCT ACTGGCAGAA TACTTTAACT TGGTATTTTC


 


1451
ATCCGAACCA TCAGTTCTAT CTCGGTGCGG ACTATGGCCG CGTATCTGGC


 


1501
GAAAGTGCAC AATATGTATC GGGCAAGCAG CTGATGGGTG CAGTGGTCGG


 


1551
CTTCAGAGGA GGGCATAAAG TAGGCGGTAT GTTTGCTTAT GATCTGTTTG


 


1601
CCGGCAAGCC GCTTCATAAA CCCAAAGGCT TTCAGACGAC CAACACCGTT


 


1651
TACGGCTTCA ACTTGAATTA CAGTTTCTAA






This corresponds to the amino acid sequence <SEQ ID 2370; ORF 707>:










m707.pep




1
MEIINDAELI RSMQRQQHID AELLTDANVR FEQPLEKNNY VLSEDETPCT


 


51
RVNYISLDDK TVRKFSFLPS VLMKETAFKT GMCLGSNNLS RLQKAAQQIL


 


101
IVRGYLTSQA IIQPQNMDSG ILKLRVSAGE IGDIRYEEKR DGKSAEGSIS


 


151
AFNNKFPLYR NKILNLRDVE QGLENLRRLP SVKTDIQIIP SEEEGKSDLQ


 


201
IKWQQNKPIR FSIGIDDAGG KTTGKYQGNV ALSFDNPLGL SDLFYVSYGR


 


251
GLAHKTDLTD ATGTETESGS RSYSVHYSVP VKKWLFSFNH NGHRYHEATE


 


301
GYSVNYDYNG KQYQSSLAAE RMLWRNRLHK TSVGMKLWTR QTYKYIDDAE


 


351
IEVQRRRSAG WEAELRHRAY LNRWQLDGKL SYKRGTGMRQ SMPAPEENGG


 


401
DILPGTSRMK IITASLDAAA PFILGKQQFF YATAIQAQWN KTPLVAQDKL


 


451
SIGSRYTVRG FDGEQSLFGE RGFYWQNTLT WYFHPNHQFY LGADYGRVSG


 


501
ESAQYVSGKQ LMGAVVGFRG GHKVGGMFAY DLFAGKPLHK PKGFQTTNTV


 


551
YGFNLNYSF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2371>:










a707.seq




1
NTGAAAGAAA CAGCTTTTAA AACTGGGATG TGTTTAGGTT CCAATAATTT


 


51
GAGCAGGCTA CAAAAAGCCG CGCAACAGAT ACTGATTGTG CGTGGCTACC


 


101
TCACTTCCCA AGCTATTATC CAACCACAGA ATATGGATTC GGGAATTCTG


 


151
AAATTACGGG TATCAGCAGG CGAAATAGGN GATATCCGCT ATGAAGAAAA


 


201
ACGGGATGNG AAGTCTGCCG AGGGCAGTAT TAGTGCATTC AATAACAAAN


 


251
TTCCCTTATA TAGGAACAAA ATTCTCAATC TTCGCGATGT AGAGCAGGGC


 


301
TTGGAAAACC TGCGTCGTTT GCCGAGTGTT AAAACAGATA TTCAGATTAT


 


351
ACCGTCCGAA GAAGAAGGCA AAAGCGATTT ACAGATCAAA TGGCAGCAGA


 


401
ATAAACCCAT ACGGTTCAGT ATCGGTATAG ATGATGCGGG CGGCAAAACG


 


451
ACCGGCAAAT ATCAAGGAAA TGTCGCTTTA TCGTNCGATA ACCCTTTGGG


 


501
NTTAAGCGAT TNGTTTTATG TTTCATATGG ACGCGGTTTG GTGCACAAAA


 


551
CGGACTTGAC TGNTGCCACC GGTACGGAAA CTGAAAGCGG ATCCAGAAGT


 


601
TACAGCGTGC ATTATTCGGT GNNCGTAAAA AAATGGCTGT TTTCTTTTAA


 


651
TCACAATGGA CATCGTTACC ACGAAGCAAC CGAAGGCTAT TCCGTCAATT


 


701
ACGATTACAA CGGCAAACAA TATCAGAGCA GCCTGGCCGC CGAGCGCATG


 


751
CTTTGGNNNN NNAGNTTTCN TNAAACTTCA GTCNGAATGA AATTATGGAC


 


801
ACGCCAAACC TATAAATACA TCGACGATGC CGAAATCGAA GTGCAACGCC


 


851
GCCGCTCTGC AGGCTGGGAA GCCGAATTGC GCCACCGTGC TTACCTCNAC


 


901
CGTTGGCAGC TTGACGGCAA GTTGTCTTAC AAACGCGGGA CCGGCATGCG


 


951
CCAAAGTATG CCCGCACCTG AAGAAAACGG CGGCGGTACT ATTCCAGNCA


 


1001
NATCCCGTAT GAAAATCATA ACCGCCGGAT TGGATGCAGC GGCCCCGTNT


 


1051
ATGTTGGGCA AACAGCAGTT TTTCTACGCA ACCGCCATTC AAGCTCAATG


 


1101
GAACAAAACG CCTTTGGTTG CCCAAGACAA GTTGTCTATC GGCAGCCGCT


 


1151
ACACCGTTCG CGGATTTGAT GGGGAGCAGA GTCTTTTCGG AGAGCGAGGT


 


1201
TTCTACTGGC AGAATACTTT AACTTGGTAT TTTCATCCGA ACCATCAGTT


 


1251
CTATCTCGGT GCGGACTATG GCCGCGTATC TGGCGAAAGT GCACAATATG


 


1301
TATCGGGCAA GCAGCTGATG GGTGCAGTGG TCGGCTTCAG AGGAGGGCAT


 


1351
AAAGTAGGCG GTATGTTTGC TTATGATCTG TTTGCCGGCA AGCCGCTTCA


 


1401
TAAACCCAAA GGCTTTCAGA CGACCAACAC CGTTTACGGC TTCAACTTGA


 


1451
ATTACAGTTT CTAA






This corresponds to the amino acid sequence <SEQ ID 2372; ORF 707.a>:










a707.pep




1
XKETAFKTGM CLGSNNLSRL QKAAQQILIV RGYLTSQAII QPQNMDSGIL


 


51
KLRVSAGEIG DIRYEEKRDX KSAEGSISAF NNKXPLYRNK ILNLRDVEQG


 


101
LENLRRLPSV KTDIQIIPSE EEGKSDLQIK WQQNKPIRFS IGIDDAGGKT


 


151
TGKYQGNVAL SXDNPLGLSD XFYVSYGRGL VHKTDLTXAT GTETESGSRS


 


201
YSVHYSVXVK KWLFSFNHNG HRYHEATEGY SVNYDYNGKQ YQSSLAAERM


 


251
LWXXXFXXTS VXMKLWTRQT YKYIDDAEIE VQRRRSAGWE AELRHRAYLX


 


301
RWQLDGKLSY KRGTGMRQSM PAPEENGGGT IPXXSRMKII TAGLDAAAPX


 


351
MLGKQQFFYA TAIQAQWNKT PLVAQDKLSI GSRYTVRGFD GEQSLFGERG


 


401
FYWQNTLTWY FHPNHQFYLG ADYGRVSGES AQYVSGKQLM GAVVGFRGGH


 


451
KVGGMFAYDL FAGKPLHKPK GFQTTNTVYG FNLNYSF*






a707/m707 95.3% identity in 486 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2373>:










g708.seq




1
ATGCCTTTTA AGCCATCCAA ACGAATCTCT TTATTACTTG TTCTTGCCTT


 


51
GGGCGCGTGC AGCACTTCCT ACCGCCCCTC GCGGGCAGAA AAAGCCAATC


 


101
AGGTTTCCAA TATCAAAACC CAGTTGGCGA TGGAATATAT GCGCGGTCAG


 


151
GACTACCGTC AGGCAACGGC AAGTATTGAA GATGCCTTGA AATCGAACCC


 


201
TAAAAACGAA CTTGCCTGGC TGGTCCGTGC CGAAATCTAT CAATACCTGA


 


251
AAGTTAACGA CAAGGCGCAG GAAAGTTTCC GGCAAGCCCT CTCCATCAAA


 


301
CCCGACAGTG CCGAAATCAA CAACAACTAC GGCTGGTTCC TGTGCGGCAG


 


351
GCTCAACCGC CCTGCCGAAT CTATGGCATA TTTCGACAAA GCCCTGGCCG


 


401
ACCCCACCTA CCCGACCCCT TATATTGCCA ACCTGAATAA AGGTATATGC


 


451
AGCGCAAAAC AGGGGCAATT CGGATTGGCG GAAGCCTATT TGAAACGTTC


 


501
CCTCGCCGCC CAGCCGCAGT TCCCACCCGC ATTTAAAGAA CTGGCGCGCA


 


551
CCAAAATGCT GGCCGGGCAG TTGGGCGATG CCGATTACTA CTTTAAAAAA


 


601
TACCAAAGCA GGGTAGAAGT CCTTCAGGCC GATGATTTGC TGCTAGGCTG


 


651
GAAAATTGCC AAAGCCCTCG GCAACGTGCA GGCGGCATAC GAATATGAAG


 


701
CACAATTGCA GGCAAATTTC CCCTACTCGG AAGAATTGCA AACCGTCCTC


 


751
ACCGGTCAAT AA






This corresponds to the amino acid sequence <SEQ ID 2374; ORF 708.ng>:










g708.pep




1
MPFKPSKRIS LLLVLALGAC STSYRPSRAE KANQVSNIKT QLAMEYMRGQ


 


51
DYRQATASIE DALKSNPKNE LAWLVRAEIY QYLKVNDKAQ ESFRQALSIK


 


101
PDSAEINNNY GWFLCGRLNR PAESMAYFDK ALADPTYPTP YIANLNKGIC


 


151
SAKQGQFGLA EAYLKRSLAA QPQFPPAFKE LARTKMLAGQ LGDADYYFKK


 


201
YQSRVEVLQA DDLLLGWKIA KALGNVQAAY EYEAQLQANF PYSEELQTVL


 


251
TGQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2375>:










m708.seq




1
ATGCCTTTTA AGCCATCCAA ACGAATCTCT TTATTACTCG TTCTTGCCTT


 


51
GGGCGCGTGC AGCACTTCCT ACCGCCCCTC GCGGGCAGAA AAAGCCAATC


 


101
AGGTTTCCAA TATCAAAACC CAGTTGGCAA TGGAATATAT GCGCGGTCAG


 


151
GACTACCGTC AGGCGACGGC AAGTATTGAA GACGCCCTGA AATCGGACCC


 


201
TAAAAACGAG CTTGCCTGGC TGGTCCGTGC CGAAATCTAT CAATACCTGA


 


251
AAGTTAACGA CAAGGCGCAG GAAAGTTTCC GGCAAGCCCT CTCCATCAAA


 


301
CCCGACAGTG CCGAAATCAA CAACAACTAC GGTTGGTTCC TATGCGGCAG


 


351
GCTCAACCGC CCTGCCGAAT CTATGGCATA TTTCGACAAA GCTCTGGCCG


 


401
ACCCCACCTA CCCGACCCCT TATATTGCCA ACCTGAATAA AGGCATATGC


 


451
AGCGCAAAAC AGGGGCAATT CGGATTGGCG GAAGCCTATT TGAAACGTTC


 


501
CCTCGCCGCC CAGCCGCAGT TCCCACCCGC ATTTAAAGAA CTGGCGCGCA


 


551
CCAAAATGCT GGCCGGGCAG TTGGGCGATG CCGATTACTA CTTTAAAAAA


 


601
TACCAAAGCA GGGTAGAAGT CCTTCAGGCC GATGATTTGC TGCTAGGCTG


 


651
GAAAATTGCC AAAGCCCTCG GCAACGCACA GGCGGCATAC GAATATGAAG


 


701
CACAATTGCA GGCGAATTTC CCCTACTCGG AAGAATTGCA AACCGTCCTC


 


751
ACCGGTCAAT AA






This corresponds to the amino acid sequence <SEQ ID 2376; ORF 708>:










m708.pep




1
MPFKPSKRIS LLLVLALGAC STSYRPSRAE KANQVSNIKT QLAMEYMRGQ


 


51
DYRQATASIE DALKSDPKNE LAWLVRAEIY QYLKVNDKAQ ESFRQALSIK


 


101
PDSAEINNNY GWFLCGRLNR PAESMAYFDK ALADPTYPTP YIANLNKGIC


 


151
SAKQGQFGLA EAYLKRSLAA QPQFPPAFKE LARTKMLAGQ LGDADYYFKK


 


201
YQSRVEVLQA DDLLLGWKIA KALGNAQAAY EYEAQLQANF PYSEELQTVL


 


251
TGQ*






m708/g708 99.2% identity in 253 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2377>:










a708.seq




1
ATGCCTTTTA AGCCATCCAA ACGAATCTCT TTATTACTTG TCCTTGCCTT


 


51
GGGCGCGTGC AGCACTTCCT ACCGCCCCTC GCGGGCAGAA AAAGCCAATC


 


101
AGGTTTCCAA TATCAAAACC CAGTTGGCAA TGGAATATAT GCGCGGTCAG


 


151
GACTACCGTC AGGNGACGGC AAGTATTGAA GACGCCTTGA AATCAGACCC


 


201
TAAAAACGAG CTTGCCTGGC TGGTCCGTGC CGAAATCTAT CAATACCTGA


 


251
AAGTTAACGA CAAGGCGCAG GAAAGTTTCC GGCAAGNCCT CTCCATCAAA


 


301
CCCGACAGTG CCGAAATCAA CAACAACTAC NGCTGGTTCC TGTGCGGCAG


 


351
GCTCAACCGC CCTGCCGAAT CTATGGCATA TTTCGACAAA GCCCTGGCCG


 


401
ACCCCACNTA CCCGANCCCT TATATTGCCA ACCTGAATAA AGGCATATGC


 


451
AGCGCAAAAC AGGGGCAATT CGGATTGGCG GAAGCCTATT TGAAACGTTC


 


501
CCTCGCCGCC CAGCCGCAGT TCCCACCCGC ATTTAAAGAA CTGGCGCGCA


 


551
CCAAAATGCT GGCCGGGCAG TTGGGCGATG CCGATTACTA CTTTAAAAAA


 


601
TACCAAAGCA GGGTAGAAGT CCTTCAGGCC GATGATTTGC TGCTAGGCTG


 


651
GAAAATTGCC AAAGCCCTCG GCAACGCACA GGCGGCATAC GAATATGAAG


 


701
CACAATTGCA GGCGAATTTC CCCTACTCGG AAGAATTGCA AACCGTCCTC


 


751
ATCGGTCAAT AA






This corresponds to the amino acid sequence <SEQ ID 2378; ORF 708.a>:










a708.pep




1
MPFKPSKRIS LLLVLALGAC STSYRPSRAE KANQVSNIKT QLAMEYMRGQ


 


51
DYRQXTASIE DALKSDPKNE LAWLVRAEIY QYLKVNDKAQ ESFRQXLSIK


 


101
PDSAEINNNY XWFLCGRLNR PAESMAYFDK ALADPTYPXP YIANLNKGIC


 


151
SAKQGQFGLA EAYLKRSLAA QPQFPPAFKE LARTKMLAGQ LGDADYYFKK


 


201
YQSRVEVLQA DDLLLGWKIA KALGNAQAAY EYEAQLQANF PYSEELQTVL


 


251
IGQ*






a708/m708 98.0% identity in 253 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2379>:










g709.seq




1
ATGTTTGCTT TCAAATCCTT ACTCGATATG CCGCGCGGTG AGGCACTTGC


 


51
CGTCGTCGTC GCTCTGATTG CCGCAATGGG CTATACCATC ATTTCATTGG


 


101
AGTGGCTGCC GCATATGTCC ATTATTGCCG CCATCGTCGT GCTGATTTTG


 


151
TACGGCTTGG CGCGCGGTTT GAAATACAAC GATATGCAGG CAGGGATGAT


 


201
AGGCGCGTTG AATCAGGGTA TGGGCGCGGT TTACCTGTTT TTCTTCATCG


 


251
GGCTGATGGT CAGCGCGCTG ATGATGAGCG GCGCGATTCC GACGCTGATG


 


301
TATTACGGTT TCGGGCTGAT TTCCCCGACT TATTTTTATT TTTCCGCCTT


 


351
CGCGCTGTGT TCCGTCATCG GCGTGTCCAT CGGCAGCAGC CTGACCGCCT


 


401
GCGCCACTGT CGGCGTTGCC TTTATGGGGA TGGCGGCGGC GTTTCAGGCC


 


451
GATATGGCGA TGACGgcggg cgcgattgTT tccggTGTGT TTTTCGGCGA


 


501
TAAAATGTCC CCGCTTTCCG ACACCACGGG CATTTCCGCG TCCATCGTCG


 


551
GTATCGACCT GTTTGAACAC ATCAAAAACA TGATGTACAC CACCATCCCT


 


601
GCGTGGCTTA TCAGCGCGGC ACTGATGCTT TGGCTTCTTC CCAGCGTCGC


 


651
CGCGCAGGAT TTGAACAGCG TCGAATCCTT CCGCAGCCAG CTTGAAGCCA


 


701
CGGGATTGGT GCACGGCTAT TCGCTGATTC CGTTTGCACT GTTGGTCGTT


 


751
TTGGCATTGA TGCGCGTCAA TGCCGTGGTC GCCATGCTCT TTACCGTCAT


 


801
TGCCGCCGTT GCCGTAACGT ATCTGCACAG CACGCCCGAT CTGCGTCAGC


 


851
TCGGCGCGTG GTTTTATGGC GGCTACAAAC TCGAAGGCGA AGCGTTTAAA


 


901
GACATTGCCA AACTGATTTC GCGCGGCGGC TTGGAGAGTA TGTTCTTTAC


 


951
GCAGACCATC GTTATCCTCG GTATGAGTTT GGGCGGGCTG CTGTTTGCGC


 


1001
TCGGTGTGAT TCCTTCCTTG CTGGAGGCCG TCCGTACCTT CTTGACGAAT


 


1051
GCCGGACGCG CGACGTTCAG CGTTGCCATG ACTTCGGTCG GGGTCAATTT


 


1101
CCTGATTGGA GAGCAATATT TGAGCATCCT GCTTTCGGGA GAAACGTTCA


 


1151
AACCCGTTTA CGACAAACTC GGCCTGCATT CGTGCAACCT GTCGCGGACT


 


1201
CTGGAAGATG CGGGGACGGT GATTAACCCG CTCGTGCCGT GGAGCGTGTG


 


1251
CGGCGTATTT ATCAGCCACG CCCTTGGCGT ACCCGTTTGG GAATATCTGC


 


1301
CTTATGCCTT TTTCTGCTAT TTGAGTTTGG CTTTAACCCT GTTATTCGGC


 


1351
TGGACGGGGC TGACTTTGAG CAAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 2380; ORF 709.ng>:










g709.pep




1
MFAFKSLLDM PRGEALAVVV ALIAAMGYTI ISLEWLPHMS IIAAIVVLIL


 


51
YGLARGLKYN DMQAGMIGAL NQGMGAVYLF FFIGLMVSAL MMSGAIPTLM


 


101
YYGFGLISPT YFYFSAFALC SVIGVSIGSS LTACATVGVA FMGMAAAFQA


 


151
DMAMTAGAIV SGVFFGDKMS PLSDTTGISA SIVGIDLFEH IKNMMYTTIP


 


201
AWLISAALML WLLPSVAAQD LNSVESFRSQ LEATGLVHGY SLIPFALLVV


 


251
LALMRVNAVV AMLFTVIAAV AVTYLHSTPD LRQLGAWFYG GYKLEGEAFK


 


301
DIAKLISRGG LESMFFTQTI VILGMSLGGL LFALGVIPSL LEAVRTFLTN


 


351
AGRATFSVAM TSVGVNFLIG EQYLSILLSG ETFKPVYDKL GLHSCNLSRT


 


401
LEDAGTVINP LVPWSVCGVF ISHALGVPVW EYLPYAFFCY LSLALTLLFG


 


451
WTGLTLSKK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2381>:










m709.seq




1
ATGTTCGCTT TCAAATCCTT ACTCGATATG CCGCGCGGTG AGGCACTTGC


 


51
CGTCGTCGTC GCTCTGATTG CCGCGATGGG CTATACCATC ATTTCATTGG


 


101
AGTGGTTGCC GCATATGTCC ATTATTGCCG CCATCGTCGT GCTGATTTTG


 


151
TACGGCTTGG CGCGCGGTTT GAAATACAAC GATATGCAGC AGGGCATGAT


 


201
AGGCGCGTTG AATCAGGGTA TGGGCGCGAT TTACCTGTTT TTCTTCATCG


 


251
GGCTGATGGT CAGCGCGCTG ATGATGAGCG GCGCGATTCC GACGCTGATG


 


301
TATTACGGTT TCGGACTGAT TTCCCCGACT TATTTTTATT TTTCCTCCTT


 


351
CGCGCTGTGT TCCGTCATCG GCGTGTCCAT CGGCAGCAGC CTGACCACCT


 


401
GCGCCACTGT CGGCGTTGCC TTTATGGGGA TGGCGGCGGC GTTTCAGGCC


 


451
GATATGGCGA TGACGGCGGG CGCGATTGTT TCGGGCGCAT TTTTTGGCGA


 


501
CAAAATGTCC CCGCTTTCGG ATACGACGGG TATTTCCGCG TCCATCGTCG


 


551
GCATCGACTT GTTTGAGCAC ATCAAAAATA TGATGTACAC CACCATCCCC


 


601
GCGTGGCTCA TTAGTGCGGC ACTGATGCTT TGGCTTTTGC CGAATGTCGC


 


651
CGCGCAGGAT TTGAACAGCG TCGAATCCTT CCGCAGCCAG CTTGAAGCCA


 


701
CGGGATTGGT GCACGGCTAT TCGCTGATTC CGTTTGCGCT GTTGGTCATT


 


751
TTGGCATTGA TGCGCATCAA CGCCGTCGTC GCCATGCTCT TTACCGTCAT


 


801
GGTTGCCGTT GCTGTAACGT ATCTGCACAG CACGCCCGAT CTGCGTCAGC


 


851
TCGGTGCGTG GTTTTACGGC GGCTACAAAC TCGAAGGCGA AGCGTTTAAA


 


901
GATGTTGTCA AACTGATTTC GCGCGGCGGT TTGGAAAGTA TGTTTTTCAC


 


951
GCAAACCATC GTGATTCTCG GGATGAGTTT GGGCGGACTG TTGTTTGCGC


 


1001
TCGGTGTGAT TCCTTCCCTG TTGGAGGCCA TCCGTACCTT CTTGACGAAT


 


1051
GCCGGACGCG CGACGTTCAG CGTTGCCATG ACTTCGGTCG GGGTTAATTT


 


1101
CCTGATCGGC GAGCAATATT TGAGTATTTT GTTGTCGGGT GAAACGTTCA


 


1151
AACCCGTTTA CGATAAGCTC GGTCTGCATT CGCGCAATCT GTCGCGGACG


 


1201
CTGGAAGATG CGGGGACGGT GATTAACCCG CTCGTACCGT GGAGCGTATG


 


1251
CGGCGTGTTC ATCAGCCACG CGCTGGGCGT GCCGGTTTGG GAATATCTGC


 


1301
CGTATGCCTT TTTCTGCTAT TTGAGTTTGG CTTTGACCCT GTTATTCGGT


 


1351
TGGACGGGGC TGACTTTGAG CAAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 2382; ORF 709>:










m709.pep




1
MFAFKSLLDM PRGEALAVVV ALIAAMGYTI ISLEWLPHMS IIAAIVVLIL


 


51
YGLARGLKYN DMQQGMIGAL NQGMGAIYLF FFIGLMVSAL MMSGAIPTLM


 


101
YYGFGLISPT YFYFSSFALC SVIGVSIGSS LTTCATVGVA FMGMAAAFQA


 


151
DMAMTAGAIV SGAFFGDKMS PLSDTTGISA SIVGIDLFEH IKNMMYTTIP


 


201
AWLISAALML WLLPNVAAQD LNSVESFRSQ LEATGLVHGY SLIPFALLVI


 


251
LALMRINAVV AMLFTVMVAV AVTYLHSTPD LRQLGAWFYG GYKLEGEAFK


 


301
DVVKLISRGG LESMFFTQTI VILGMSLGGL LFALGVIPSL LEAIRTFLTN


 


351
AGRATFSVAM TSVGVNFLIG EQYLSILLSG ETFKPVYDKL GLHSRNLSRT


 


401
LEDAGTVINP LVPWSVCGVF ISHALGVPVW EYLPYAFFCY LSLALTLLFG


 


451
WTGLTLSKK*






m709/g709 96.9% identity in 459 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2383>:










a709.seq




1
ATGTTCGCTT TCNAATCCTT ACTCGATATG CCGCGCGGTG AGGCNCTTGC


 


51
CGTCGTCGTC GCTCTGATTG CCGCGATGGG CTATACCATC ATTTNNTTGG


 


101
AGTGGCTGCC GCATATGTCC ATTATTGCCG CCATCGTNGT GCTGATTTTG


 


151
TACGGCTTGG CGCGCGGTTT GAAATACAAC GATATGCAGC AGGGCATGAT


 


201
AGGCGCGTTG AATCAGGGTA TGGGCGCGAT TTACCTNTTT TTCTTCATCG


 


251
GGCTGATGGT CAGCGCGCTG ATGATGAGCG GCGCGATTCC GACGCTGATG


 


301
TATTACGGTT TCGGACTGAT TTCCCCGACT TATTTTTATT TTTCCGCCTT


 


351
CGCGCTGTGT TCCGTCATCG GCGTGTCCAT CGGCAGCAGC CTGACCACCT


 


401
GCGCCACTGT CGGCGTTGCC TTNATGGGTA TNNNGNCGGC GTTTCNGGCC


 


451
NANATGGNGN NGNNGNNGGN CNNGATTGTN NNGGNCGCAT TNTTNGGCGN


 


501
CAAAATGTCN CCGCTTTCCG ATACGNCGGG CATNTCCGCG TCCATTGTCG


 


551
GTATCGACCT GTTTGAACAC ATCAAAAATA TGATGTACAC NACCATTCCC


 


601
GCGTGGCTCA TCAGTGNNNC ACTGATGCTG TNGCTTCTTC CCAGCGTCGC


 


651
CGCGCAGGAT TTGAACAGCG TCGAATCCTT CCGCAGCCAG CTTGAAGCCA


 


701
CGGGATTGGT GCACTGCTAT TCGCTGATTC CGTTTGCGCT GTTGGTCGTT


 


751
TTGGCATTGA TGCGCGTCAA TGCCGTGGTC GCTATGCTCT TTACCGTCAT


 


801
TGCCGCCGTT GCCGTAACGT ATCTGCACAG CACGCCCGAT CTGCGTCAGC


 


851
TCGGCGCGTG GTTTTACGGC GGCTACAAAC TCGAAGGCGA AGCGTNTANA


 


901
GACATTGCCA AACTCATTTC TCGCGGCGGT TTGGAAAGTA TGTTTTTCAC


 


951
GCAGACCATC GTGATTCTTG GGATGAGCCT TGGCGGGCTG CTGTTTGCAC


 


1001
TGGGCGCGAT TCCTTCCCTG CTGGATGCCG TCCGCAGCTT TTTGACGAAT


 


1051
GCCGGGCGTN CCACATTCAG CGTTGCCATG ACTTCGGTCG GGGTTAATTT


 


1101
CCTGATCGGC GAGCAATATT TGAGTATTTT GTTGTCNGGT GAAACGTTCA


 


1151
AACCTGTTTA CGATAAGCTC GGTCTGCATT CGCGCAATCT GTCGCGGACG


 


1201
CTGGAAGATG CGGGGACGGT CATCAACCCG CTCGTACCGT GGAGCGTATG


 


1251
CGGCGTGTTC ATCANCCACG CGCTGGGCGT GCCGGTTTGG GAATATCTGC


 


1301
CGTATGCCTT TTTCTGCTAT TTGAGTTTGG CTTTGACCCT GTTATTCGGT


 


1351
TGGACGGGGC TGACTTTGAG CAAAAAATAA






This corresponds to the amino acid sequence <SEQ ID 2384; ORF 709.a>:










a709.pep




1
MFAFXSLLDM PRGEALAVVV ALIAAMGYTI IXLEWLPHMS IIAAIVVLIL


 


51
YGLARGLKYN DMQQGMIGAL NQGMGAIYLF FFIGLMVSAL MMSGAIPTLM


 


101
YYGFGLISPT YFYFSAFALC SVIGVSIGSS LTTCATVGVA XMGXXXAFXA


 


151
XMXXXXXXIV XXAXXGXKMS PLSDTXGXSA SIVGIDLFEH IKNMMYTTIP


 


201
AWLISXXLML XLLPSVAAQD LNSVESFRSQ LEATGLVHCY SLIPFALLVV


 


251
LALMRVNAVV AMLFTVIAAV AVTYLHSTPD LRQLGAWFYG GYKLEGEAXX


 


301
DIAKLISRGG LESMFFTQTI VILGMSLGGL LFALGAIPSL LDAVRSFLTN


 


351
AGRXTFSVAM TSVGVNFLIG EQYLSILLSG ETFKPVYDKL GLHSRNLSRT


 


401
LEDAGTVINP LVPWSVCGVF IXHALGVPVW EYLPYAFFCY LSLALTLLFG


 


451
WTGLTLSKK*






a709/m709 91.1% identity in 459 aa overlap





g710.seq not found
g710.pep not found
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2385>:









m710.seq




1
ATGGAAACCC ACGAAAAAAT CCGCCTGATG CGCGAATTGA ATAAATGGTC


 


51
CCAGGAGGAT ATGGCGGAAA AGCTGGCGAT GTCGGCAGGC GGGTATGCCA


 


101
AAATCGAACG GGGCGAAACG CAGTTAAATA TCCCGCGTTT GGAGCAGTTG


 


151
GCTCAGATTT TCAAAATCGA TATGTGGGAC TTGCTCAAAT CGGGCGGTGG


 


201
TGGGATGGTG TTTCAGATTA ATGAAGGTGA TAGTGGTGGC GATATTGCGT


 


251
TGTATGCGTC GGGTGATGTT TCGATGAAAA TAGAATTTTT AAAAATGGAG


 


301
TTGAAACACT GCAAAGAAAT GTTGGAACAA AAAGACAAAG AAATCGAGCT


 


351
GCTCCGCAAG CTGACCGAAA CCGTTTAA






This corresponds to the amino acid sequence <SEQ ID 2386; ORF 710>:










m710.pep




1
METHEKIRLM RELNKWSQED MAEKLAMSAG GYAKIERGET QLNIPRLEQL


 


51
AQIFKIDMWD LLKSGGGGMV FQINEGDSGG DIALYASGDV SMKIEFLKME


 


101
LKHCKEMLEQ KDKEIELLRK LTETV*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2387>:










a710.seq




1
ATGGAAACCC ACGAAAAAAT CCGCCTGATG CGCGAATTGA ATAAATGGTC


 


51
CCAGGAGGAT ATGGCGGAAA AGCTGGCGAT GTCGGCAGGC GGGTATGCCA


 


101
AAATCGAACG AGGCGAAACG CAGTTGAATA TCCCGCGTTT GGAGCAGTTG


 


151
GCGCAGATTT TCAAAATTGA TATGTGGGAC TTGCTCAAAT CGGGCGGCGG


 


201
CGGGATGGTG TTGCAGATTA ACGATGTGGA TACCAACAGC GGGGAATTTG


 


251
CAATCTATAC CGCTCAGGAT GCATCNGGTA AAGCTGGATT TGTTAAAATG


 


301
GAATTAAAAC ACTGTAAAGA AATGTTGGAA CACAAAGACA AAGAAATCGA


 


351
GCTGCTCCGC AAGCTGACCG AAACCGTTTA A






This corresponds to the amino acid sequence <SEQ ID 2388; ORF 710.a>:










a710.pep




1
METHEKIRLM RELNKWSQED MAEKLAMSAG GYAKIERGET QLNIPRLEQL


 


51
AQIFKIDMWD LLKSGGGGMV LQINDVDTNS GEFAIYTAQD ASGKAGFVKM


 


101
ELKHCKEMLE HKDKEIELLR KLTETV*






a710/m710 85.7% identity in 126 aa overlap





g711.seq not found
g711.pep not found
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2389>:









m711.seq




1
ATGCCCGCGC CTGATTTGGG ATTTGCCTTA AGTCTGCCGC CAAAAAAGGC


 


51
AATCGAGTGG CTGGAAAGTA AAAAGGTTAC GGCGGAGAGC TACCGCAATC


 


101
TGACAGCCTC CGAAATTGCC AAAGTCTATA CGATTGCCCG CATGACCGAC


 


151
TTGGATATGC TCAACGACAT CAAAACTTCG ATGGTTGAAT CGGCAAAAAG


 


201
TGGACAGTCG TTTGACGATT GGCGAAAAGG TATCTTGAAT CTGCTCAGCA


 


251
ACAAGGGCTG GCTGCATCCG AACGGGCATA ACGGTAAGGA TATCATCGAC


 


301
CCAGCCACCG GCGAGGTATT CGGTTCGCCG CGGAGGTTGG AGACGATTTA


 


351
CCGTACCAAT ATGCAAACTG CCTACAACGC CGGTCAATAT CAAGGATATA


 


401
TGGCAAATAT TGATGCACGA CCTTATTGGA TGTATGACGC GGTAGGCGAC


 


451
AGCCGCACCC GTCCGGCGCA TTCGGCAATA GACGGGCTGG TGTACCGCTA


 


501
CGACGACCCG TTTTGGGCAA CGTTTTACCC GCCCAACGGC TACAACTGCC


 


551
GCTGCTCGGT CATCGCGCTG TCGGAGCGGG ATGTGGAACG CCAGGGGCGG


 


601
ATTGTTGGGC AAAGCACGGC GGACAATCTG GTCGAGACCC ATAAAATCTA


 


651
CAACAAAAAA GGCGATACTT ATCTGACCCT TGCCTATAAA GCACCGGATG


 


701
GCAGTCTGTA CACGACCGAT CGAGGATTTG ATTACAACGC CGGACGAATG


 


751
AACTACCGCC CCGATTTAGA CAAGTACGAC CGTGCGTTGG CGCATCAATT


 


801
TGCCAAAGCG GAAATGGGTG GTGCGGATTT TAAAACCAGC TTTAAACAGC


 


851
TTGAAAAAGA GTTTTATGAA GTCAAGCAAC GTTTGGATAT TGATGGCAAG


 


901
CCCGATAAAG AGCAGAAAAT CAAAATCCGA AATGCGCTAT CAAGACAGCT


 


951
TAAATTTGCT GCGGGTGTAT TGAGCAAGGA AACGCAAGAA TTGGCAGGTA


 


1001
TGACACGAGC GACGGTGTGG CTGTCTGATG ATACGTTGGT TAAACAGGTA


 


1051
GACAGCCGTG AGGGGCAGAA TTTCGATGAC TCCTACTATG CTTTTTTGCC


 


1101
GGATATGCTG CAAAACCCTG AACATGTCAT CCGCGACAAT CGTGAATTGA


 


1151
TTTTCACAGC TCGCTATAAA GGCTCGGCAT TGTGGGCAGT TTTAAAATAT


 


1201
ATTAAGGAGG TGGATGAGAT TTATCTACAG TCGTACCGAA TCAGTAACGA


 


1251
CAAAGAGATT GCCAAATTTA TGGCGAAGAA GAAAGTATTG AAATAG






This corresponds to the amino acid sequence <SEQ ID 2390; ORF 711>:










m711.pep




1
MPAPDLGFAL SLPPKKAIEW LESKKVTAES YRNLTASEIA KVYTIARMTD


 


51
LDMLNDIKTS MVESAKSGQS FDDWRKGILN LLSNKGWLHP NGHNGKDIID


 


101
PATGEVFGSP RRLETIYRTN MQTAYNAGQY QGYMANIDAR PYWMYDAVGD


 


151
SRTRPAHSAI DGLVYRYDDP FWATFYPPNG YNCRCSVIAL SERDVERQGR


 


201
IVGQSTADNL VETHKIYNKK GDTYLTLAYK APDGSLYTTD RGFDYNAGRM


 


251
NYRPDLDKYD RALAHQFAKA EMGGADFKTS FKQLEKEFYE VKQRLDIDGK


 


301
PDKEQKIKIR NALSRQLKFA AGVLSKETQE LAGMTRATVW LSDDTLVKQV


 


351
DSREGQNFDD SYYAFLPDML QNPEHVIRDN RELIFTARYK GSALWAVLKY


 


401
IKEVDEIYLQ SYRISNDKEI AKFMAKKKVL K*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2391>:










a711.seq




1
ATGCCCGCGC CTGATTTGGG ATTTGCCTTA AGTCTGCCGC CAAAAAAGGC


 


51
AATCGAGTGG CTGGAAAGTA AAAAGGTTAC GGCGGAGAGC TACCGCAATC


 


101
TGACAGCCTC CGAAATTGCC AAAGTCTATA CGATTGCCCG CATGACCGAC


 


151
TTGGATATGC TCAACGACAT CAAAACTTCG ATGGTTGAAT CGGCAAAAAG


 


201
TGGACAGTCG TTTGACGATT GGCGAAAAGG TATCTTGAAT CTGCTCAGCA


 


251
ACAAGGGCTG GCTGCATCCG AACGGGCATA ACGGTAAGGA TATCATCGAC


 


301
CCAGCCACCG GCGAGGTATT CGGTTCGCCG CGGAGGTTGG AGACGATTTA


 


351
CCGTACCAAC ATGCAAACTG CCTACAACGC CGGTCAATAT CAAGGATATA


 


401
TGGCAAATAT TGATGCACGA CCTTATTGGA TGTATGACGC GGTAGGCGAC


 


451
AGCCGCACCC GTCCGGCGCA TTCGGCAATA GACGGGCTGG TGTACCGCTA


 


501
CGACGACCCG TTTTGGGCAA CGTTTTACCC GCCCAACGGC TACAACTGCC


 


551
GTTGCTCGGT CATCGCGCTG TCGGAGCGGG ATGTGGAACG CCAGGGGCGG


 


601
ATTGTCGGGC AAAGCACGTC GGACAATCTT GTTGAGACCC ATAAAATCTA


 


651
CAACAAAAAA GGCGATACTT ATCTGACCCT TGCCTATAAA GCACCGGATG


 


701
GCAGTCTGTA CACGACCGAT CGAGGATTTG ATTACAACGC CGGACGAATG


 


751
AACTACCGCC CCGATTTAGA CAAGTACGAC CGTGCGTTGG CGCATCAATT


 


801
TGCCAAAGCG GAAATGGGTG GTGCGGATTT TAAAACCAGC TTTAAACAGC


 


851
TTGAAAAAGA GTTTTATGAA GTCAAGCAAC GTTTGGATAT TGATGGCAAG


 


901
CCCGATAAAG AGCAGAAAAT CAAAATCCGA AATGCGCTAT CAAGACAGCT


 


951
TAAATTTGCT GCGGGTGTAT TGAGCAAGGA AACGCAAGAA TTGGCAGGTA


 


1001
TGACACGAGC GACGGTGTGG CTGTCTGATG ATACGTTGGT TAAACAGGTA


 


1051
GACAGCCGTG AAGGGCAGAA TTTCGATGAC TCCTACTATG CTTTTTTGCC


 


1101
GGATATGCTG CAAAACCCTG AACATGTCAT CCGCGACAAT CGTGAATTGA


 


1151
TTTTCACAGC TCGCTATAAA GGCTCGGCAT TGTGGGCAGT TTTAAAATAT


 


1201
ATTAAGGAGG TGGATGAGAT TTATCTACAG TCGTACCGAA TCAGTAACGA


 


1251
CAAAGAGATT GCCAAATTTA TGGCGAAGAA GAAAGTATTG AAATAG






This corresponds to the amino acid sequence <SEQ ID 2392; ORF 711.a>:










a711.pep




1
MPAPDLGFAL SLPPKKAIEW LESKKVTAES YRNLTASEIA KVYTIARMTD


 


51
LDMLNDIKTS MVESAKSGQS FDDWRKGILN LLSNKGWLHP NGHNGKDIID


 


101
PATGEVFGSP RRLETIYRTN MQTAYNAGQY QGYMANIDAR PYWMYDAVGD


 


151
SRTRPAHSAI DGLVYRYDDP FWATFYPPNG YNCRCSVIAL SERDVERQGR


 


201
IVGQSTSDNL VETHKIYNKK GDTYLTLAYK APDGSLYTTD RGFDYNAGRM


 


251
NYRPDLDKYD RALAHQFAKA EMGGADFKTS FKQLEKEFYE VKQRLDIDGK


 


301
PDKEQKIKIR NALSRQLKFA AGVLSKETQE LAGMTRATVW LSDDTLVKQV


 


351
DSREGQNFDD SYYAFLPDML QNPEHVIRDN RELIFTARYK GSALWAVLKY


 


401
IKEVDEIYLQ SYRISNDKEI AKFMAKKKVL K*






a711/m711 99.8% identity in 431 aa overlap





g712.seq not found yet
g712.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2393>:









m712.seq




1
ATGATGCCCC ATATTGATTT TGACACGATT CCGGGCAGCA TCCGCGTGCC


 


51
CGGGCAGTAT ATTGAATTTA ACACCCGCAA TGCCGTACAA GGTTTGCCGC


 


101
AAAATCCGCA AAAGGTATTG ATGGTTGCAC CCATGCTGAC CGCGGGCATA


 


151
CAGACCGTCT TAGAGCCGGT GCAACTATTT AGCGATGCCG AGGCGGCCGA


 


201
TTTGTTCGGA CAAGGCTCGC TGGCGCATTT GATGGTGCGC CAAGCATTTG


 


251
CCAACAACCC TTATTTGGAT TTGACCGTTA TCGGTATTGC CGACCACAGC


 


301
GCAGGCGTGC AGGCAACCGC AACCGTTACC CTTTCCGGCA CGGCCACCGC


 


351
GCCGGGCGTG GTGGAAATCA CGATTGGCGG CAAGCAGGTA AGCACGGCCG


 


401
TTAACACCGG CGAGACCGCC GCCACAGTGG CAGACCGTCT GAAAACCGCC


 


451
ATCACTGCCG CCGATGTAAC CGTTACCGCA TCCGGCAGCG GCGCAGCCGT


 


501
TACGCTGACG GCCAAACACA AAGGCGAGAT CGGCAACGAG AGCGGCTTAA


 


551
CCGTGAGCAC CGGCAATACC GGCCTAACTT ATCAAGCCAA TGCCTTTACC


 


601
GGCGGTGCCA AAAATGCGGA CATTGCCACG GCCTTGTCCA AAGTGGCGGG


 


651
CAAGCATTAT CACATTATTT GCAGCCCGTT TAGCGATGAC GCCAACGCCA


 


701
AAGCCTTGAG CAACCATATT ACCAACGTAT CCAACGCCAT CGAGCAGCGC


 


751
GGCTGTATCG GCGTATTGGG TATGAGTGCG GCCTTGAGCA CGGCCACCAC


 


801
CGCTACCGGC GAAATCAACG ACGGCCGCAT GACCTGTGCT TGGTACAAAG


 


851
GTGCGGTAGA GCCAAACGGC ATCATCGCCG CAGGTTATGC GGCGGTGTTG


 


901
GCCTTTGAAG AAGACCCTGC CAAGCCGCTG AACACGCTGG AAATCAAAGG


 


951
GCTGGCCGTT ACACCTGATG CGCAATGGCC GCTGTTTGCA GAATGCAACA


 


1001
ATGCGCTGTA CAACGGCTTG ACCCCGCTCA CAGTGGTCAA CAACCGCGTG


 


1051
CAGATTATGC GTGCCGTATC CACCTATACC AAGTCGGCCA ACAACACCGA


 


1101
CGACCCGGCA CTACTCGACA TTACCACCAT CCGCACGCTG GATTATGTGC


 


1151
GCCGCAGCGT TAAAGAGCGC ATTGCCCTGC GTTTTCCGCG CGACAAATTG


 


1201
AGCGACCGCC TGCTGCCCAA GGTTAAGAGC GAGATTTTGG ACGTGCTGAT


 


1251
TAAGCTCGAC CAAGCCGAAA TCATCGAAAA CGCCGAGGCC AACAAAGGCA


 


1301
AGCTGGTGGT GGCGCGTGCG CAAAACGACC CCAACCGTGT TAATGCCATT


 


1351
ATCACTGCCG ATGTGGTCAA CGGCCTGCAC GTCTTTGCCG GGCGCATTGA


 


1401
TTTGATTTTG TAA






This corresponds to the amino acid sequence <SEQ ID 2394; ORF 712>:










m712.pep




1
MMPHIDFDTI PGSIRVPGQY IEFNTRNAVQ GLPQNPQKVL MVAPMLTAGI


 


51
QPALEPVQLF SDAEAADLFG QGSLAHLMVR QAFANNPYLD LTVIGIADHS


 


101
AGVQATATVT LSGTATAPGV VEITIGGKQV STAVNTGETA ATVADRLKTA


 


151
ITAADVTVTA SGSGAAVTLT AKHKGEIGNE SGLTVSTGNT GLTYQANAFT


 


201
GGAKNADIAT ALSKVAGKHY HIICSPFSDD ANAKALSNHI TNVSNAIEQR


 


251
GCIGVLGMSA ALSTATTATG EINDGRMTCA WYKGAVEPNG IIAAGYAAVL


 


301
AFEEDPAKPL NTLEIKGLAV TPDAQWPLFA ECNNALYNGL TPLTVVNNRV


 


351
QIMRAVSTYT KSANNTDDPA LLDITTIRTL DYVRRSVKER IALRFPRDKL


 


401
SDRLLPKVKS EILDVLIKLD QAEIIENAEA NKGKLVVARA QNDPNRVNAI


 


451
IPADVVNGLH VFAGRIDLIL *






a712.seq not found yet
a712.pep not found yet
g713.seq not found yet
g713.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2395>:









m713.seq




1
ATGCAAAATA ATTCATACGG CTATGCCGTG TCGGTGCGCG TGGGCGGTAA


 


51
AGAGCACCGC CACTGGGAGC GCTACGACAT CGACAGCGAC TTTTTAATCC


 


101
CTGCCGACAG CTTCGATTTT GTCATCGGCA GGTTGGGACC GGAGGCGGCC


 


151
ATACCCGATT TAAGCGGAGA GAGCTGCGAG GTAGTGATAG ACGGGCAAAT


 


201
CGTGATGACG GGCATCATCG GCAGCCAGCG CCACGGCAAA AGCAAGGGCA


 


251
GCCGCGAGTT GAGCTTGAGC GGGCGTGATT TGGCCGGTTT TTTGGTGGAT


 


301
TGCTCCGCGC CGCAGCTCAA TGTAAAGGGC ATGACGGTAT TGGATGCAGC


 


351
CAAAAAGCTG GCCGCGCCGT GGCCGCAGAT TAAAGCGGTG GTGCTTAAGG


 


401
CCGAAAACAA CCCCGCTTTG GGCAAAATCG ACATCGAGCC GGGCGAAACC


 


451
GTATGGCAGG CATTAACCCA TATTGCCAAC TCGGTCGGGC TGCATCCGTG


 


501
GCTGGAGCCG GACGGCACGT TGGTGGTGGG CGGTGCGGAT TACAGCAGCC


 


551
CGCCGGTGGC GACATTGTGT TGGAGCCGCA CCGACAGCCG CTGCAATATC


 


601
GAGCGCATGG ACATTGAGTG GGATACCGAC AACCGCTTTT CCGAGGTTAC


 


651
TTTTTTGGCG CAATCGCACG GCCGCAGCGG CGACAGCGCC AAACACGATT


 


701
TAAAGTGGGT GTACAAAGAC CCGACGATGA CGCTGCACCG CCCTAAAACG


 


751
GTGGTGGTGT CCGATGCCGA CAATTTGGCC GCATTGCAAA AGCAGGCTAA


 


801
AAAGCAGCTG GCCGACTGGC GGCTGGAGGG ATTTACACTC ACGATAACCG


 


851
TGGGCGGCCA TAAAACCCGC GACGGCGTAT TGTGGCAACC TGGCCTGCGT


 


901
GTGCATGTGA TCGACGACGA GCACGGTATC GATGCGGTGT TTTTTCTGAT


 


951
GGGGCGGCGG TTTATGCTAT CCCGCATGGA TGGTACGCAA ACCGAGCTGC


 


1001
GGCTCAAAGA GGACGGTATT TGGACACCCG ACGCTTACCC CAAAAAGGCC


 


1051
GAGGCGGCGC GCAAGCGCAA AGGCAAACGC AAAGGCGTGA GCCATAAGGG


 


1101
CAAAAAAGGC GGCAAAAAAC AAGCAGAAAC GGCGGTGTTT GAATGA






This corresponds to the amino acid sequence <SEQ ID 2396; ORF 713>:










m713.pep




1
MQNNSYGYAV SVRVGGKEHR HWERYDIDSD FLIPADSFDF VIGRLGPEAA


 


51
IPDLSGESCE VVIDGQIVMT GIIGSQRHGK SKGSRELSLS GRDLAGFLVD


 


101
CSAPQLNVKG MTVLDAAKKL AAPWPQIKAV VLKAENNPAL GKIDIEPGET


 


151
VWQALTHIAN SVGLHPWLEP DGTLVVGGAD YSSPPVATLC WSRTDSRCNI


 


201
ERMDIEWDTD NRFSEVTFLA QSHGRSGDSA KHDLKWVYKD PTMTLHRPKT


 


251
VVVSDADNLA ALQKQAKKQL ADWRLEGFTL TITVGGHKTR DGVLWQPGLR


 


301
VHVIDDEHGI DAVFFLMGRR FMLSRMDGTQ TELRLKEDGI WTPDAYPKKA


 


351
EAARKRKGKR KGVSHKGKKG GKKQAETAVF E*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2397>:










a713.seq




1
ATGCAAAATA ATTCATACGG CTATGCCGTG TCGGTGCGCG TGGGCGGTAA


 


51
AGAGCACCGC CACTGGGAGC GCTACGACAT CGACAGCGAC TTTTTAATCC


 


101
CTGCCGACAG CTTCGATTTT GTCATCGGCA GGTTGGGGCC GGAGGCGGCC


 


151
ATACCCGATT TAAGCGGAGA GAGCTGCGAG GTAGTGATAG ACGGGCAAAT


 


201
CGTGATGACG GGCATCATCG GCAGCCAGCG CCACGGCAAA AGCAAGGGCG


 


251
GCCGCGAGTT GAGCTTGAGC GGGCGTGATT TGGCCGGTTT TTTGGTGGAT


 


301
TGCTCCGCGC CGCAGCTCAA TGTAAAGGGC ATGACGGTAT TGGATGCAGC


 


351
CAAAAAGCTG GCCGCGCCGT GGCCGCAGAT TAAAGCGGTG GTGCTTAAGG


 


401
TCGAAAACAA CCCCGCTTTG GACAAAATCG ACATCGAGCC GGGCGAAACC


 


451
GTATGGCAGG CATTAACCCA TATTGCCAAC TCGGTCGGGC TGCATCCGTG


 


501
GCTGGAGCCG GACGGCACGT TGGTGGTGGG CGGTGTGGAT TACAGCAGCC


 


551
CGCCGGTGGC GACATTGTGT TGGAGCCGCA CCGACAGCCG CCGCAATATC


 


601
GAGCGCATGG ACATTGAGTG GGATACCGAC AACCGCTTTT CTGAGGTTAC


 


651
TTTTTTGGCG CAATCGCACG GCCGCAGCGG CGACAGCGCC AAACACGATT


 


701
TAAAGTGGGT GTACAAAGAC CCGACGATGA CGCTGCACCG CCCTAAAACG


 


751
GTGGTGGTGT CCGATGCCGA CAATTTGGCC GCATTGCAAA AGCAGGCTAA


 


801
AAAGCAGCTG GCCGACTGGC GGCTGGAGGG ATTTACACTC ACGATAACCG


 


851
TGGGCGGCCA TAAAACCCGC GACGGCGTAT TGTGGCAACC TGGCCAGCGT


 


901
GTGCATGTGA TCGACGACGA GCACGGTATC GATGCGGTGT TTTTTCTGAT


 


951
GGGGCGGCGG TTTATGCTAT CTCGCATGGA TGGCACGCAA ACCGAGCTGC


 


1001
GGCTCAAAGA GGACGGTATT TGGACACCCG ACGCTTACCC CAAAAAGGCC


 


1051
GAGGCGGCGC GCAAGCGCAA AGGCAAACGC AAAGGCGTGA GCCATAAGGG


 


1101
CAAAAAAGGC GGCAAAAAAC AAGCAGAAAC GGCGGTGTTT GAATGA






This corresponds to the amino acid sequence <SEQ ID 2398; ORF 713.a>:










a713.pep




1
MQNNSYGYAV SVRVGGKEHR HWERYDIDSD FLIPADSFDF VIGRLGPEAA


 


51
IPDLSGESCE VVIDGQIVMT GIIGSQRHGK SKGGRELSLS GRDLAGFLVD


 


101
CSAPQLNVKG MTVLDAAKKL AAPWPQIKAV VLKVENNPAL DKIDIEPGET


 


151
VWQALTHIAN SVGLHPWLEP DGTLVVGGVD YSSPPVATLC WSRTDSRRNI


 


201
ERMDIEWDTD NRFSEVTFLA QSHGRSGDSA KHDLKWVYKD PTMTLHRPKT


 


251
VVVSDADNLA ALQKQAKKQL ADWRLEGFTL TITVGGHKTR DGVLWQPGQR


 


301
VHVIDDEHGI DAVFFLMGRR FMLSRMDGTQ TELRLKEDGI WTPDAYPKKA


 


351
EAARKRKGKR KGVSHKGKKG GKKQAETAVF E*






a713/m713 98.4% identity in 381 aa overlap





g714.seq not found yet
g714.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2399>:









m714.seq




1
ATGAGCTATC AAGACATCTT GCGGGGCCTG TTGCCCCCCG TGTCGTATGC


 


51
CCGCAATGCC CCGCGTGTGC GGGCGCAGGC AGAAATAGAC GGCGCAGCGC


 


101
TGGATGCGGT GGCGGAATCG GCTCAAAGCG TTGCCGATGC CGTCGACCCG


 


151
CGCAGCGCCG GCCAAATGCT GGCCGATTGG GAGCGCGTAT TAGGTTTGGA


 


201
CGGTACGGGC AAAAACCGCC AGCACCGTGT GTTGGCCGTC ATGGCCAAGC


 


251
TAAACGAAAC AGGCGGCTTG AGTATTCCTT ATTTTGTGCG TTTGGCCGAG


 


301
GCGGCGGGCT ATCAAATCCA AATCGACGAA CCGCAGCCGT TCCGCGCCGG


 


351
TGTAAACCGC GCCGGCGACC GTCTTGCGCC GCAGGAAATC ATGTGGGTGT


 


401
GGCACGTTAA CGTGCGCGGC GGCAACAACC GCATTACCCG ATTCCGCGCC


 


451
GGTATCTCGG CGGCGGGCGA CAGGCTGACC GATTACAGCG ATGCCGTGAT


 


501
CGAGAGCCTG TTCAACCGCC TCAAGCCCGC CCACACCGCT ATCCGATTTA


 


551
CCTACCGCTA A






This corresponds to the amino acid sequence <SEQ ID 2400; ORF 714>:










m714.pep




1
MSYQDILRGL LPPVSYARNA PRVRAQAEID GAALDAVAES AQSVADAVDP


 


51
RSAGQMLADW ERVLGLDGTG KNRQHRVLAV MAKLNETGGL SIPYFVRLAE


 


101
AAGYQIQIDE PQPFRAGVNR AGDRLAPQEI MWVWHVNVRG GNNRITRFRA


 


151
GISAAGDRLT DYSDAVIESL FNRLKPAHTA IRFTYR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2401>:










a714.seq




1
ATGAGCTATC AAGACATCTT GCGGGGTCTG TTGCCCCCCG TGTCGTATGC


 


51
CCGCAATGCC CCGCGTGTGC GGGCGCAGGC AGAAATAGAC GGCGCAGCGC


 


101
TGGATGCGGT GGCGGAATCG GCTCAAAGCG TTGCCGATGC CGTCGACCCG


 


151
AGCAGCGCCG GCCAAATGCT GGCCGATTGG GAGCGCGTAT TAGGTTTGGA


 


201
CGGTACGGGC AAAAACCGCC AGCGCCGTGT GTTGGCCGTC ATGGCCAAGC


 


251
TAAACGAAAC AGGCGGCTTG AGTATTCCTT ATTTTGTGCG TTTGGCCGAG


 


301
GCGGCGGGCT ATCAAATCCA AATCGACGAA CCGCAGCCGT TCCGCGCCGG


 


351
TGTAAACCGC GCCGGCGACC GTCTTGCGCC GCAGGAAATC ATGTGGGTGT


 


401
GGCACGTTAA CGTGCGCGGC GGCAACAACC GCATTACCCG ATTCCGCGCC


 


451
GGTATCTCGG CGGCGGGCGA CAGGCTGACC GATTACAGCG ATGCCGTGAT


 


501
CGAGAGCCTG TTCAACCGCC TCAAGCCCGC CCACACCGCT ATCCGATTTA


 


551
CCTACCGATA A






This corresponds to the amino acid sequence <SEQ ID 2402; ORF 714.a>:










a714.pep




1
MSYQDILRGL LPPVSYARNA PRVRAQAEID GAALDAVAES AQSVADAVDP


 


51
SSAGQMLADW ERVLGLDGTG KNRQRRVLAV MAKLNETGGL SIPYFVRLAE


 


101
AAGYQIQIDE PQPFRAGVNR AGDRLAPQEI MWVWHVNVRG GNNRITRFRA


 


151
GISAAGDRLT DYSDAVIESL FNRLKPAHTA IRFTYR*






a714/m714 98.9% identity in 186 aa overlap





g715.seq not found yet
g715.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2403>:









m715.seq




1
ATGATTGATG TCAAAATAGA CAATATCTTT GTCGTCCTAA ACCAAATCGA


 


51
GCGGCTTGGC AACGGGATCG AAAACCGCTA CCTGCTGATG CGCCGACTGT


 


101
CCGAAACCAT GCACACGGCG GTCAAGCTCA ATTTCCGCTA CGCAGGCCGT


 


151
CCGAAATGGG TTGGGCTAAA ATACCGCGAC GGCAAGCCGC TTTCGGATTC


 


201
GGGTCGTCTG AAAGACAGTT TTTCCACACT GTCAGACAAC GATACAGCCC


 


251
TTGTCGGTAC GAATATCGTC TATGCCGCCA TCCACAACTT CGGCGGTATG


 


301
GCGGGGCGCA ACCGCAAAGT TCGGATTCCG CAACGGGAAT TTTTGACGCT


 


351
GACGGACGAC GACAAACAGG CTTTGATGGA CGATGTGCAG GATTATTTTT


 


401
CGGGTCTGAT ACCGTGA






This corresponds to the amino acid sequence <SEQ ID 2404; ORF 715>:










m715.pep




1
MIDVKIDNIF VVLNQIERLG NGIENRYLLM RRLSETMHTA VKLNFRYAGR


 


51
PKWVGLKYRD GKPLSDSGRL KDSFSTLSDN DTALVGTNIV YAAIHNFGGM


 


101
AGRNRKVRIP QREFLTLTDD DKQALMDDVQ DYFSGLIP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2405>:










a715.seq




1
ATGATTGATG TCAAAATAGA CAATATCTTT GTCGTCCTAA ACCAAATCGA


 


51
GCGGCTTGGC AACGGGATCG AAAACCGCTA CCTGCTGATG CGCCGACTGT


 


101
CCGAAACCAT GCACACGGCG GTCAAGCTCA ATTTCCGCTA CGCAGGCCGT


 


151
CCGAAATGGT TGGGGCTAAA ATACCGCGAC GGCAAGCCGC TTTCGGATTC


 


201
GGGTCGTCTG AAAGACAGTT TTTCCACACT GTCAGACAAC GATACAGCCC


 


251
TTGTCGGTAC GAATATCGTC TATGCCGCCA TCCACAACTT CGGCGGTATG


 


301
GCGGGGCGCA ACCGCAAAGT TCGGATTCCG CAACGGGAAT TTTTGACGCT


 


351
GACGGACGAC GACAAACAGG CTTTGATGGA CGATGTGCAG GATTATTTTT


 


451
CGGGTCTGAT ACCGTGA






This corresponds to the amino acid sequence <SEQ ID 2406; ORF 715.a>










a715.pep




1
MIDVKIDNIF VVLNQIERLG NGIENRYLLM RRLSETMHTA VKLNFRYAGR


 


51
PKWLGLKYRD GKPLSDSGRL KDSFSTLSDN DTALVGTNIV YAAIHNFGGM


 


101
AGRNRKVRIP QREFLTLTDD DKQALMDDVQ DYFSGLIP*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2407>:










g716.seq




1
ATGAACAAAA ATATTGCTGC CGCACTCGCC GGTGCTTTAT CCCTGTCTCT


 


51
GGCCGCCGGC GCCGTTGCCG CCCACAAACC GGCAAGCAAC GCAACAGGCG


 


101
TTCAAAAATC CGCCCAAGGC TCTTGCGGCG CATCCAAATC TGCCGAAGGT


 


151
TCGTGCGGCG CATCCAAATC TGCCGAAGGT TCGTGCGGCG CGGCTGCTTC


 


201
TAAAGCAGGC GAAGGCAAAT GCGGCGAGGG CAAATGCGGT GCAACTGTAA


 


251
AAAAAGCCCA CAAACACACC AAAGCATCTA AAGCCAAAGC CAAATCTGCC


 


301
GAAGGCAAAT GCGGCGAAGG CAAATGCGGT TCTAAATAA






This corresponds to the amino acid sequence <SEQ ID 2408; ORF 716.ng>:










g716.pep




1
MNKNIAAALA GALSLSLAAG AVAAHKPASN ATGVQKSAQG SCGASKSAEG


 


51
SCGASKSAEG SCGAAASKAG EGKCGEGKCG ATVKKAHKHT KASKAKAKSA


 


101
EGKCGEGKCG SK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2409>:










m716.seq




1
ATGAACAAAA ACATTGCTGC CGCTCTCGCC GGTGCTTTAT CCCTGTCTTT


 


51
GGCCGCCGGT GCAGTTGCTG CCAACAAACC GGCAAGCAAC GCAACAGGCG


 


101
TTCATAAATC CGCCCATGGC TCTTGCGGCG CGTCCAAATC TGCCGAAGGT


 


151
TCGTGCGGCG CGGCTGGTTC TAAAGCAGGC GAAGGCAAAT GCGGCGAGGG


 


201
CAAATGCGGT GCGACCGTAA AAAAAACCCA CAAACACACC AAAGCATCTA


 


251
AAGCCAAGGC CAAATCTGCC GAAGGCAAAT GCGGCGAAGG CAAATGCGGT


 


301
TCTAAATAA






This corresponds to the amino acid sequence <SEQ ID 2410; ORF 716>:










m716.pep




1
MNKNIAAALA GALSLSLAAG AVAANKPASN ATGVHKSAHG SCGASKSAEG


 


51
SCGAAGSKAG EGKCGEGKCG ATVKKTHKHT KASKAKAKSA EGKCGEGKCG


 


101
SK*






m716/g716 86.6% identity in 112 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2411>:










a716.seq




1
ATGAACAAAA ACATTGCTGC CGCACTCGCC GGTGCTTTAT CCCTGTCTTT


 


51
GGCCGCCGGT GCAGTTGCTG CCAACAAACC GGCAAGCAAC GCAACAGGCG


 


101
TTCATAAATC CGCCCATGGC TCTTGCGGCG CGTCCAAATC TGCCGAAGGT


 


151
TCGTGCGGCG CGGCTGGTTC TAAAGCAGGC GAAGGCAAAT GCGGCGAGGG


 


201
CAAATGCGGT GCGACCGTAA AAAAAACCCA CAAACACACC AAAGCATCTA


 


251
AAGCCAAGGC CAAATCTGCC GAAGGCAAAT GCGGCGAAGG CAAATGCGGT


 


301
TCTAAATAA






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2412.a>:










a716.pep




1
MNKNIAAALA GALSLSLAAG AVAANKPASN ATGVHKSAHG SCGASKSAEG


 


51
SCGAAGSKAG EGKCGEGKCG ATVKKTHKHT KASKAKAKSA EGKCGEGKCG


 


101
SK*






a716/m716 100.0% identity in 102 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2413>:










g717.seq




1
ATGGACACAA AAGAAATCCT CGGCTACGCG GCAGGCTCGA TCGGCAGCGC


 


51
GGTTTTAGCC GTCATCATCC TGCCGCTGCT GTCGTGGTAT TTCcccgCCG


 


101
ACGACATCGG GCGCATCGTG CTGATGCAGA CGGCGGCGGG ACTGACGGTG


 


151
TCGGTATTGT GCCTCGGGCT GGATCAGGCA TACGTCCGCG AATACTATGC


 


201
CGCCGCCGAC AAAGACACTT TGTTCAAAAC CCTGTTCCTG CCGCCGCTGC


 


251
TGTTTTCCGC CGCGATAGCC GCCCTGCTGC TTTCCCGCCC GTCCCTGCCG


 


301
TCTGAAATCC TGTTTTCGCT CGACGATGCC GCCGCCGGCA TCGGGCTGGT


 


351
GCTGTTTGAA CTGAGCTTCC TGCCCATCCG CTTTCTCTTA CTGGTTTTGC


 


401
GTATGGAAGG GCGCGCCCTT GCCTTTTCGT CCGCGCAACT CGTGCCCAAA


 


451
CTCGCCATTC TGCTGCTGTT GCCGCTGACG GTCGGGCTGC TGCACTTTCC


 


501
GGCGAACACC TCCGTCCTGA CCGCCGTTTA CGCGCTGGCA AACCTTGCCG


 


551
CCGCCGCCTT TTTGCTGTTT CAAAACCGAT GCCGTCTGAA GGCCGTCCGG


 


601
CGCGCGCCGT TTTCGCCCGC CGTCCTGCAC CGGGGGCTGC GCTACGGCAT


 


651
ACCGCTCGCA CTGAGCAGCC TTGCCTATTG GGGGCTGGCA TCCGCCGACC


 


701
GTTTGTTCCT GAAAAAATAT GCGGGCCTGG AACAGCTCGG CGTTTATTCG


 


751
ATGGGTATTT CGTTCGGCGG GGCGGCATTA TTGCTCCAAA GCATCTTTTC


 


801
AACGGTCTGG ACACCGTATA TTTTCCGTGC AATCGAAGAA AACGCCACGC


 


851
CCGCCCGCCT CTCGGCAACG GCAGAATCCG CCGCCGCCCT GCTTGCCTCC


 


901
GCCCTCTGCC TGACCGGAAT TTTCTCGCCC CTCGCCTCCC TCCTGCTGCC


 


951
GGAAAACTAC GCCGCCGTCC GGTTTACCGT CGTATCGTGT ATGCTGccgc


 


1001
cgctGTTTTA CACGCTGACC GAAATCAGCG GCATCGGTTT GAACGTCGTC


 


1051
CGCAAAACGC GTCCGATCGC GCTTGCCACC TTGGGCGCGC TGGCGGCAAA


 


1101
CCTGCTGCTG CTGGGGCTTG CCGTACCGTC CGGCGGCACG CGCGGCGCGG


 


1151
CGGTTGCCTG TGCCGCCTCA TTCTGGTTGT TTTTTGTTTT CAAGACAGAA


 


1201
AGCTCCTGCC GCCTGTGGCA GCCGCTCAAA CGCCTGCCGC TTTATATGCA


 


1251
CACATTGTTC TGCCTgGCCT CCTCGGCGGC CTACACCTGC TTCGGCACAC


 


1301
CGGCAAACTA CCCcctgttt gccggcgtAT GGGCGGCATA TCTGGCAGGC


 


1351
TGCATCCTGC GCCACCGGAA AAATTTGCAC AAACTGTTTC ATTATTTGAA


 


1401
AAAACAAGGT TTCCCATTAT GA






This corresponds to the amino acid sequence <SEQ ID 2414; ORF 717.ng>:










g717.pep




1
MDTKEILGYA AGSIGSAVLA VIILPLLSWY FPADDIGRIV LMQTAAGLTV


 


51
SVLCLGLDQA YVREYYAAAD KDTLFKTLFL PPLLFSAAIA ALLLSRPSLP


 


101
SEILFSLDDA AAGIGLVLFE LSFLPIRFLL LVLRMEGRAL AFSSAQLVPK


 


151
LAILLLLPLT VGLLHFPANT SVLTAVYALA NLAAAAFLLF QNRCRLKAVR


 


201
RAPFSPAVLH RGLRYGIPLA LSSLAYWGLA SADRLFLKKY AGLEQLGVYS


 


251
MGISFGGAAL LLQSIFSTVW TPYIFRAIEE NATPARLSAT AESAAALLAS


 


301
ALCLTGIFSP LASLLLPENY AAVRFTVVSC MLPPLFYTLT EISGIGLNVV


 


351
RKTRPIALAT LGALAANLLL LGLAVPSGGT RGAAVACAAS FWLFFVFKTE


 


401
SSCRLWQPLK RLPLYMHTLF CLASSAAYTC FGTPANYPLF AGVWAAYLAG


 


451
CILRHRKNLH KLFHYLKKQG FPL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2415>:










m717.seq




1
ATGGACACAA AAGAAATCCT CGGCTACGCG GCAGGCTCGA TCGGCAGCGC


 


51
GGTTTTAGCC GTCATCATCC TGCCGCTGCT GTCGTGGTAT TTCCCCGCCG


 


101
ACGACATCGG GCGCATCGTG CTGATGCAGA CGGCGGCGGG GCTGACGGTG


 


151
TCGGTGTTGT GCCTCGGGCT GGATCAGGCA TACGTCCGCG AATACTATGC


 


201
CACCGCCGAC AAAGACACCT TGTTCAAAAC CCTGTTCCTG CCGCCGCTGC


 


251
TGTCTGCCGC CGCGATAGCC GCCCTGCTGC TTTCCCGCCC GTCCCTGCCG


 


301
TCTGAAATCC TGTTTTCACT CGACGATGCC GCCGCCGGCA TCGGGCTGGT


 


351
GCTGTTTGAA CTGAGCTTCC TGCCCATCCG CTTTCTCTTA CTGGTTTTGC


 


401
GTATGGAAGG ACGCGCCCTT GCCTTTTCGT CCGCGCAACT CGTGCCCAAG


 


451
CTCGCCATCC TGCTGCTGCT GCCGCTGACG GTCGGGCTGC TGCACTTTCC


 


501
AGCGAACACC GCCGTCCTGA CCGCCGTTTA CGCGCTGGCA AACCTTGCCG


 


551
CCGCCGCCTT TTTGCTGTTT CAAAACCGAT GCCGTCTGAA GGCCGTCCGG


 


601
CACGCACCGT TTTCGCCCGC CGTCCTGCAC CGGGGGCTGC GCTACGGCAT


 


651
ACCGATCGCA CTGAGCAGCA TCGCCTATTG GGGGCTGGCA TCCGCCGACC


 


701
GTTTGTTCCT GAAAAAATAT GCCGGCCTGG AACAGCTCGG CGTTTATTCG


 


751
ATGGGTATTT CGTTCGGCGG GGCGGCATTA TTGTTCCAAA GCATCTTTTC


 


801
AACGGTCTGG ACACCGTATA TTTTCCGCGC AATCGAAGAA AACGCCCCGC


 


851
CCGCCCGCCT CTCGGCAACG GCAGAATCCG CCGCCGCCCT GCTTGCCTCC


 


901
GCCCTCTGCC TGACCGGCAT TTTCTCGCCC CTTGCCTCCC TCCTGCTGCC


 


951
GGAAAACTAC GCCGCCGTCC GGTTTATCGT CGTATCGTGT ATGCTGCCGC


 


1001
CGCTGTTTTG CACGCTGGCG GAAATCAGCG GCATCGGTTT GAACGTCGTC


 


1051
CGCAAAACGC GCCCGATCGC GCTCGCCACC TTGGGCGCGC TGGCGGCAAA


 


1101
CCTGCTGCTG CTGGGGCTTG CCGTGCCGTC CGGCGGCGCG CGCGGCGCGG


 


1151
CGGTTGCCTG TGCCGCCTCA TTCTGGCTGT TTTTTGCCTT CAAGACCGAA


 


1201
AGCTCCTGCC GCCTGTGGCA GCCGCTCAAA CGCCTGCCGC TTTATCTGCA


 


1251
CACATTGTTC TGCCTGACCT CCTCGGCGGC CTACACCTGC TTCGGCACGC


 


1301
CGGCAAACTA TCCCCTGTTT GCCGGCGTAT GGGCGGCATA TCTGGCAGGC


 


1351
TGCATCCTGC GCCACCGGAA AGATTTGCAC AAACTGTTTC ATTATTTGAA


 


1401
AAAACAAGGT TTCCCATTAT GA






This corresponds to the amino acid sequence <SEQ ID 2416; ORF 717>:










m717.pep




1
MDTKEILGYA AGSIGSAVLA VIILPLLSWY FPADDIGRIV LMQTAAGLTV


 


51
SVLCLGLDQA YVREYYATAD KDTLFKTLFL PPLLSAAAIA ALLLSRPSLP


 


101
SEILFSLDDA AAGIGLVLFE LSFLPIRFLL LVLRMEGRAL AFSSAQLVPK


 


151
LAILLLLPLT VGLLHFPANT AVLTAVYALA NLAAAAFLLF QNRCRLKAVR


 


201
HAPFSPAVLH RGLRYGIPIA LSSIAYWGLA SADRLFLKKY AGLEQLGVYS


 


251
MGISFGGAAL LFQSIFSTVW TPYIFRAIEE NAPPARLSAT AESAAALLAS


 


301
ALCLTGIFSP LASLLLPENY AAVRFIVVSC MLPPLFCTLA EISGIGLNVV


 


351
RKTRPIALAT LGALAANLLL LGLAVPSGGA RGAAVACAAS FWLFFAFKTE


 


401
SSCRLWQPLK RLPLYLHTLF CLTSSAAYTC FGTPANYPLF AGVWAAYLAG


 


451
CILRHRKDLH KLFHYLKKQG FPL*






m717/g717 96.4% identity in 473 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2417>:










a717.seq




1
ATGGACACAA AAGAAATCCT CGGCTACGCG GCAGGCTCGA TCGGCAGCGC


 


51
GGTTTTAGCC GTCATCATCC TGCCGCTGCT GTCGTGGTAT TTCCCTGCCG


 


101
ACGACATCGG ACGCATCGTG CTGATGCAGA CGGCGGCGGG GCTGACGGTG


 


151
TCGGTGTTGT GCCTCGGGCT GGATCAGGCA TACGTCCGCG AATACTATGC


 


201
CGCCGCCGAC AAAGACACTT TGTTCAAAAC CCTGTTCCTG CCGCCGCTGC


 


251
TGTCTGCCGC CGCGATAGCC GCCCTGCTGC TTTTCCGCGC ATCCCTGCCG


 


301
TCTGAAATCC TGTTTTCGCT CGACGATGCC GCCGCCGGCA TCGGGCTGGT


 


351
GCTGTTTGAA CTGAGCTTCC TGCCCATCCG CTTTCTCTTA CTGGTTTTGC


 


401
GTATGGAAGG ACGCGCCCTT GCCTTTTCGT CCGCGCAACT CGTGTCCAAG


 


451
CTCGCCATCC TGCTGCTGCT GCCGCTGACG GTCGGGCTGC TGCACTTTCC


 


501
GGCGAACACC GCCGTCCTGA CCGCCGTTTA CGCGCTGGCA AACCTTGCCG


 


551
CCGCCGCCTT TTTGCTGTTT CAAAACCGAT GCCGTCTGAA GGCCGTCCGG


 


601
CGCGCACCGT TTTCATCCGC CGTCCTGCAT CGCGGCCTGC GCTACGGCAT


 


651
ACCGATCGCA CTAAGCAGCA TCGCCTATTG GGGGCTGGCA TCCGCCGACC


 


701
GTTTGTTCCT GAAAAAATAT GCCGGCCTAG AACAGCTCGG CGTTTATTCG


 


751
ATGGGTATTT CGTTCGGCGG AGCGGCATTA TTGTTCCAAA GCATCTTTTC


 


801
AACGGTCTGG ACACCGTATA TTTTCCGCGC AATCGAAGCA AACGCCCCGC


 


851
CCGCCCGCCT CTCGGCAACG GCAGAATCCG CCGCCGCCTT GCTTGCCTCC


 


901
GCCCTCTGCC TGACCGGCAT TTTCTCGCCC CTCGCCTCCC TCCTGCTGCC


 


951
GGAAAACTAC GCCGCCGTCC GGTTTATCGT CGTATCGTGT ATGCTGCCTC


 


1001
CGCTGTTTTG CACGCTGGTA GAAATCAGCG GCATCGGTTT GAACGTCGTC


 


1051
CGAAAAACAC GCCCGATCGC GCTCGCCACC TTGGGCGCGC TGGCGGCAAA


 


1101
CCTGCTGCTG CTGGGGCTTG CCGTACCGTC CGGCGGCGCG CGCGGCGCGG


 


1151
CGGTTGCCTG TGCCGCCTCA TTTTGGCTGT TTTTTGTTTT CAAGACCGAA


 


1201
AGCTCCTGCC GCCTGTGGCA GCCGCTCAAA CGCCTGCCGC TTTATATGCA


 


1251
CACATTGTTC TGCCTGGCCT CCTCGGCGGC CTACACCTGC TTCGGCACTC


 


1301
CGGCAAACTA CCCCCTGTTT GCCGGCGTAT GGGCGGTATA TCTGGCAGGC


 


1351
TGCATCCTGC GCCACCGGAA AGATTTGCAC AAACTGTTTC ATTATTTGAA


 


1401
AAAACAAGGT TTCCCATTAT GA






This corresponds to the amino acid sequence <SEQ ID 2418; ORF 717.a>:










a717.pep




1
MDTKEILGYA AGSIGSAVLA VIILPLLSWY FPADDIGRIV LMQTAAGLTV


 


51
SVLCLGLDQA YVREYYAAAD KDTLFKTLFL PPLLSAAAIA ALLLSRPSLP


 


101
SEILFSLDDA AAGIGLVLFE LSFLPIRFLL LVLRMEGRAL AFSSAQLVSK


 


151
LAILLLLPLT VGLLHFPANT AVLTAVYALA NLAAAAFLLF QNRCRLKAVR


 


201
RAPFSSAVLH RGLRYGIPIA LSSIAYWGLA SADRLFLKKY AGLEQLGVYS


 


251
MGISFGGAAL LFQSIFSTVW TPYIFRAIEA NAPPARLSAT AESAAALLAS


 


301
ALCLTGIFSP LASLLLPENY AAVRFIVVSC MLPPLFCTLV EISGIGLNVV


 


351
RKTRPIALAT LGALAANLLL LGLAVPSGGA RGAAVACAAS FWLFFVFKTE


 


401
SSCRLWQPLK RLPLYMHTLF CLASSAAYTC FGTPANYPLF AGVWAVYLAG


 


451
CILRHRKDLH KLFHYLKKQG FPL*






a717/m717 97.9% identity in 473 aa overlap





g718.seq not found yet
g718.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2419>:









m718.seq




1
TCAGACGGCC TTTACGTACC CCGAAACTTT ATCCACCGCC CGCAAAGCTG


 


51
GTTCAAATGG GACAAAGACA ACGGGCTGCT GCTGCGTACC CGCGAAAATC


 


101
CGGAAGGCGA AGCGTTGTGG CCGCTGGGCT GGGTCGTTCA TACCCAAAAA


 


151
TCGCGCAGCG TCCAGCAGGC GCGCAACGGG CTTTTCCGCA CGCTTTCCTG


 


201
GCTGTATATG TTCAAACACT ACGCCGTCCA CGATTTTGCC GAGTTTTTGG


 


251
AGCTGTACGG CATGCCCATC CGTATCGGCA AATACGGCGC GGGCGCAACC


 


301
AAAGAGGAAA AAAACACCCT GCTTCGAGCG GTGGCGGAAA TCGGTCACAA


 


351
CGCGGCAGGC ATCATGCCAG AAGGTATGGA AATAGAGCTC CACAACGCGG


 


401
CAAACGGTAC GACGGCAACC AGCAATCCGT TTTTGCAGAT GGCCGACTGG


 


451
TGCGAAAAAT CGGCGGCGCG GCTGATTTTG GGGCAAACGC TGACCAGCGG


 


501
TGCGGACGGA AAATCCAGCA CCAACGCGCT GGGCAATATC CACAACGAGG


 


551
TACGCCGCGA TTTGCTGGTG TCGGACGCAA AACAGGTGGC GCAAACCATC


 


601
ACAAGCCAAA TCATCGGACC GTTCCTGCAA ATCAACTATC CCCATGCCGA


 


651
CCCAAACCGC GTGCCGAAAT TTGAATTTGA CACGCGCGAG CCGAAAGACA


 


701
TCGCGGTCTT TGCCGACGCT ATCCCGAAAC TGGTGGATGT CGGCGTACAA


 


751
ATCCCCGAAA GCTGGGTGCG CGACAAACTG GTCATTCCAG ATGTGCAGGA


 


801
GGGTGAGGCT GTGTTGGTGC GGCAGGTACC GGACAATCCG GTAAACAGAA


 


851
CTGCATTGGC GGCTTTATCC GCCCACACCG TACCATCTAA GGCTACGGGC


 


901
AGGCATCAGG AAATATTGGA CGGCGCGTTG GATGACGCGC TGGTTGAGCC


 


951
CGATTTCAAT TCTCAGCTCA ACCCGATGGT GCGTCAGGCG GTTGCCGCAC


 


1001
TTAATGCTTG CAACAGCTAC GAGGAGGCAG ATGCCGCACT GAATGCGCTT


 


1051
TATCCGAATT TGGACAACGC GAAACTGCGT ACCTATATGC AGCAGGCCTT


 


1101
GTTTATCAGC GATATTTTGG GACAAGACCA TGCCCGCGCC TGA






This corresponds to the amino acid sequence <SEQ ID 2420; ORF 718>:










m718.pep




1
SDGLYVPRNF IHRPQSWFKW DKDNGLLLRT RENPEGEALW PLGWVVHTQK


 


51
SRSVQQARNG LFRTLSWLYM FKHYAVHDFA EFLELYGMPI RIGKYGAGAT


 


101
KEEKNTLLRA VAEIGHNAAG IMPEGMEIEL HNAANGTTAT SNPFLQMADW


 


151
CEKSAARLIL GQTLTSGADG KSSTNALGNI HNEVRRDLLV SDAKQVAQTI


 


201
TSQIIGPFLQ INYPHADPNR VPKFEFDTRE PKDIAVFADA IPKLVDVGVQ


 


251
IPESWVRDKL VIPDVQEGEA VLVRQVPDNP VNRTALAALS AHTVPSKATG


 


301
RHQEILDGAL DDALVEPDFN SQLNPMVRQA VAALNACNSY EEADAALNAL


 


351
YPNLDNAKLR TYMQQALFIS DILGQDHARA *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2421>:










a718.seq




1
ATGGAGCCGA TAATGGCAAA AAAGAACAAT AAAACTAAAA TCCAAAAGCC


 


51
CGAAGCTGCA TTGCAGACGG ACGTGGCTCA AATTACAGCG ACCGGTCGAG


 


101
TTATCGCCGA GCATCCATCC AATTTTATTA CGCCGCAAAA GATGCGCGCC


 


151
CTCTTCGAGG ACGCAGAAAG CGGTGACATC CGCGCCCAAC ACGAGCTTTT


 


201
CGCGGACATT GAGGAGCGCG ACAGCGACAT CGCGGCAAAT ATGGGGACGC


 


251
GCAAACGCGC GCTGCTGACG CTCAACTGGC GCGTCGCCCC GCCGCGAAAT


 


301
GCGACGCCCG AAGAAGAAAA GCTGTCCGAC CAAGCCTACG AAATGATGGA


 


351
CAGCCTGCCT ACCCTCGAAG ACCTGATTAT GGATTTGATG GACGCGGTAG


 


401
GGCACGGATT TTCTGCGTTG GAGGTCGAGT GGGTATTTTC AGACGGCCTT


 


451
TACCTACCCC GAAACTTTAT CCACCGCCCG CAAAGCTGGT TCAAATGGGA


 


501
CAAAGACAAC GGGCTGCTGC TGCGTACCCG CGAAAATCCG GAAGGCGAAG


 


551
CGTTGTGGCC GCTGGGCTGG GTCGTTCATA CCCAAAAATC GCGCAGCGTC


 


601
CAGCAGGCGC GCAACGGGCT TTTCCGCACG CTTTCCTGGC TGTATATGTT


 


651
CAAACACTAC GCCGTCCACG ATTTTGCCGA GTTTTTGGAG CTGTACGGCA


 


701
TGCCCATCCG TATCGGCAAA TACGGCGCGG GCGCAACCAA AGAGGAAAAA


 


751
AACACCCTGC TTCGAGCGGT GGCGGAAATC GGTCACAACG CGGCAGGCAT


 


801
CATGCCAGAA GGTATGGAAA TCGAGCTGCA CAACGCGGCA AACGGCATGA


 


851
CTTCCGCCGG CAATCCGTTT TTGCAGATGG CCGACTGGTG CGAAAAATCG


 


901
GCGGCGCGGC TGATTTTGGG GCAAACGCTA ACCAGCGGTG CGGACGGAAA


 


951
ATCCAGCACC AACGCGCTGG GCAATATCCA CAACGAGATA CGCCGCGATT


 


1001
TGCTGGTGTC GGACGCAAAA CAGGTGGCGC AAACCATCAC AAGCCAAATC


 


1051
ATCGGACCGT TCCTGCAAAT CAACTATCCC CATGCCGACC CAAACCGCGT


 


1101
GCCGAAATTT GAATTTGACA CGCGCGAGCC GAAAGACATC GCGGTCTTTG


 


1151
CCGACGCTAT CCCGAAACTG GTGGATGTCG GCGTACAAAT CCCCGAAAGC


 


1201
TGGGTGCGCG ACAAACTGGT CATTCCAGAT GTGCAGGAGG GTGAGGCTGT


 


1251
GTTGGTGCGG CAGGTACCGG ACAATCCGGT AAACAGAACT GCATTGGCGG


 


1301
CTTTATCCGC CCACACCGTA CCATCTAAGG CTACGGGCAG GCATCAGGAA


 


1351
ATATTGGACG GCGCGTTGGA TGACGCGCTG GTTGAGCCCG ATTTCAATTC


 


1401
TCAGCTCAAC CCGATGGTGC GTCAGGCGGT TGCCGCACTT AATGCTTGCA


 


1451
ACAGCTACGA GGAGGCAGAT GCCGCACTGA ATGCGCTTTA TCCGAATTTG


 


1501
GACAACGCGA AACTGCGTAC CTATATGCAG CAGGCCTTGT TTATCAGCGA


 


1551
TATTTTGGGA CAAGACCATG CCCGCGCCTG A






This corresponds to the amino acid sequence <SEQ ID 2422; ORF 718.a>:










a718.pep




1
MEPIMAKKNN KTKIQKPEAA LQTDVAQITA TGRVIAEHPS NFITPQKMRA


 


51
LFEDAESGDI RAQHELFADI EERDSDIAAN MGTRKRALLT LNWRVAPPRN


 


101
ATPEEEKLSD QAYEMMDSLP TLEDLIMDLM DAVGHGFSAL EVEWVFSDGL


 


151
YLPRNFIHRP QSWFKWDKDN GLLLRTRENP EGEALWPLGW VVHTQKSRSV


 


201
QQARNGLFRT LSWLYMFKHY AVHDFAEFLE LYGMPIRIGK YGAGATKEEK


 


251
NTLLRAVAEI GHNAAGIMPE GMEIELHNAA NGMTSAGNPF LQMADWCEKS


 


301
AARLILGQTL TSGADGKSST NALGNIHNEI RRDLLVSDAK QVAQTITSQI


 


351
IGPFLQINYP HADPNRVPKF EFDTREPKDI AVFADAIPKL VDVGVQIPES


 


401
WVRDKLVIPD VQEGEAVLVR QVPDNPVNRT ALAALSAHTV PSKATGRHQE


 


451
ILDGALDDAL VEPDFNSQLN PMVRQAVAAL NACNSYEEAD AALNALYPNL


 


501
DNAKLRTYMQ QALFISDILG QDHARA*






a718/m718 98.4% identity in 380 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2423>:










m718-1.seq




1
ATGGAGCCGA TAATGGCAAA AAAGAACAAT AAAACTAAAA TCCAAAAGCC


 


51
CGAAGCTGCA TTGCAGACGG ACGTGGCTCA AATTACGGCG ACCGGTCGGG


 


101
TTATCGCCGA GCATCCGTCC AATTTTATTA CGCCGCAAAA GATGCGGGCC


 


151
CTCTTCGAGG ACGCAGAAAG CGGCGACATC CGCGCCCAAC ACGAGCTTTT


 


201
CGCGGACATT GAGGAGCGCG ACAGCGACAT CGCGGCAAAT ATGGGGACGC


 


251
GCAAACGCGC GCTGCTGACG CTCAACTGGC GCGTCGCCCC GCCGCGAAAT


 


301
GCGACGCCCG AAGAAGAAAA GCTGTCCGAC CAAGCCTACG AAATGATGGA


 


351
CAGCCTGCCT ACCCTCGAAG ACCTGATTAT GGATTTGATG GACGCGGTAG


 


401
GGCACGGATT TTCTGCGTTG GAGGTCGAGT GGGTATTTTC AGACGGCCTT


 


451
TACCTACCCC GAAACTTTAT CCACCGCCCG CAAAGCTGGT TCAAATGGGA


 


501
CAAAGACAAC GGGCTGCTGC TGCGTACCCG CGAAAATCCG GAAGGCGAAG


 


551
CGTTGTGGCC GCTGGGCTGG GTCGTTCATA CCCAAAAATC GCGCAGCGTC


 


601
CAGCAGGCGC GCAACGGGCT TTTCCGCACG CTTTCCTGGC TGTATATGTT


 


651
CAAACACTAC GCCGTCCACG ATTTTGCCGA GTTTTTGGAG CTGTACGGCA


 


701
TGCCCATCCG TATCGGCAAA TACGGCGCGG GCGCAACCAA AGAGGAAAAA


 


751
AACACCCTGC TTCGAGCGGT GGCGGAAATC GGTCACAACG CGGCAGGCAT


 


801
CATGCCAGAA GGTATGGAAA TAGAGCTCCA CAACGCGGCA AACGGTACGA


 


851
CGGCAACCAG CAATCCGTTT TTGCAGATGG CCGACTGGTG CGAAAAATCG


 


901
GCGGCGCGGC TGATTTTGGG GCAAACGCTG ACCAGCGGTG CGGACGGAAA


 


951
ATCCAGCACC AACGCGCTGG GCAATATCCA CAACGAGGTA CGCCGCGATT


 


1001
TGCTGGTGTC GGACGCAAAA CAGGTGGCGC AAACCATCAC AAGCCAAATC


 


1051
ATCGGACCGT TCCTGCAAAT CAACTATCCC CATGCCGACC CAAACCGCGT


 


1101
GCCGAAATTT GAATTTGACA CGCGCGAGCC GAAAGACATC GCGGTCTTTG


 


1151
CCGACGCTAT CCCGAAACTG GTGGATGTCG GCGTACAAAT CCCCGAAAGC


 


1201
TGGGTGCGCG ACAAACTGGT CATTCCAGAT GTGCAGGAGG GTGAGGCTGT


 


1251
GTTGGTGCGG CAGGTACCGG ACAATCCGGT AAACAGAACT GCATTGGCGG


 


1301
CTTTATCCGC CCACACCGTA CCATCTAAGG CTACGGGCAG GCATCAGGAA


 


1351
ATATTGGACG GCGCGTTGGA TGACGCGCTG GTTGAGCCCG ATTTCAATTC


 


1401
TCAGCTCAAC CCGATGGTGC GTCAGGCGGT TGCCGCACTT AATGCTTGCA


 


1451
ACAGCTACGA GGAGGCAGAT GCCGCACTGA ATGCGCTTTA TCCGAATTTG


 


1501
GACAACGCGA AACTGCGTAC CTATATGCAG CAGGCCTTGT TTATCAGCGA


 


1551
TATTTTGGGA CAAGACCATG CCCGCGCCTG A






This corresponds to the amino acid sequence <SEQ ID 2424; ORF 718-1>:










m718-1.pep.




1
MEPIMAKKNN KTKIQKPEAA LQTDVAQITA TGRVIAEHPS NFITPQKMRA


 


51
LFEDAESGDI RAQHELFADI EERDSDIAAN MGTRKRALLT LNWRVAPPRN


 


101
ATPEEEKLSD QAYEMMDSLP TLEDLIMDLM DAVGHGFSAL EVEWVFSDGL


 


151
YLPRNFIHRP QSWFKWDKDN GLLLRTRENP EGEALWPLGW VVHTQKSRSV


 


201
QQARNGLFRT LSWLYMFKHY AVHDFAEFLE LYGMPIRIGK YGAGATKEEK


 


251
NTLLRAVAEI GHNAAGIMPE GMEIELHNAA NGTTATSNPF LQMADWCEKS


 


301
AARLILGQTL TSGADGKSST NALGNIHNEV RRDLLVSDAK QVAQTITSQI


 


351
IGPFLQINYP HADPNRVPKF EFDTREPKDI AVFADAIPKL VDVGVQIPES


 


401
WVRDKLVIPD VQEGEAVLVR QVPDNPVNRT ALAALSAHTV PSKATGRHQE


 


451
ILDGALDDAL VEPDFNSQLN PMVRQAVAAL NACNSYEEAD AALNALYPNL


 


501
DNAKLRTYMQ QALFISDILG QDHARA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2425>:










a718.seq




1
ATGGAGCCGA TAATGGCAAA AAAGAACAAT AAAACTAAAA TCCAAAAGCC


 


51
CGAAGCTGCA TTGCAGACGG ACGTGGCTCA AATTACAGCG ACCGGTCGAG


 


101
TTATCGCCGA GCATCCATCC AATTTTATTA CGCCGCAAAA GATGCGCGCC


 


151
CTCTTCGAGG ACGCAGAAAG CGGTGACATC CGCGCCCAAC ACGAGCTTTT


 


201
CGCGGACATT GAGGAGCGCG ACAGCGACAT CGCGGCAAAT ATGGGGACGC


 


251
GCAAACGCGC GCTGCTGACG CTCAACTGGC GCGTCGCCCC GCCGCGAAAT


 


301
GCGACGCCCG AAGAAGAAAA GCTGTCCGAC CAAGCCTACG AAATGATGGA


 


351
CAGCCTGCCT ACCCTCGAAG ACCTGATTAT GGATTTGATG GACGCGGTAG


 


401
GGCACGGATT TTCTGCGTTG GAGGTCGAGT GGGTATTTTC AGACGGCCTT


 


451
TACCTACCCC GAAACTTTAT CCACCGCCCG CAAAGCTGGT TCAAATGGGA


 


501
CAAAGACAAC GGGCTGCTGC TGCGTACCCG CGAAAATCCG GAAGGCGAAG


 


551
CGTTGTGGCC GCTGGGCTGG GTCGTTCATA CCCAAAAATC GCGCAGCGTC


 


601
CAGCAGGCGC GCAACGGGCT TTTCCGCACG CTTTCCTGGC TGTATATGTT


 


651
CAAACACTAC GCCGTCCACG ATTTTGCCGA GTTTTTGGAG CTGTACGGCA


 


701
TGCCCATCCG TATCGGCAAA TACGGCGCGG GCGCAACCAA AGAGGAAAAA


 


751
AACACCCTGC TTCGAGCGGT GGCGGAAATC GGTCACAACG CGGCAGGCAT


 


801
CATGCCAGAA GGTATGGAAA TCGAGCTGCA CAACGCGGCA AACGGCATGA


 


851
CTTCCGCCGG CAATCCGTTT TTGCAGATGG CCGACTGGTG CGAAAAATCG


 


901
GCGGCGCGGC TGATTTTGGG GCAAACGCTA ACCAGCGGTG CGGACGGAAA


 


951
ATCCAGCACC AACGCGCTGG GCAATATCCA CAACGAGATA CGCCGCGATT


 


1001
TGCTGGTGTC GGACGCAAAA CAGGTGGCGC AAACCATCAC AAGCCAAATC


 


1051
ATCGGACCGT TCCTGCAAAT CAACTATCCC CATGCCGACC CAAACCGCGT


 


1101
GCCGAAATTT GAATTTGACA CGCGCGAGCC GAAAGACATC GCGGTCTTTG


 


1151
CCGACGCTAT CCCGAAACTG GTGGATGTCG GCGTACAAAT CCCCGAAAGC


 


1201
TGGGTGCGCG ACAAACTGGT CATTCCAGAT GTGCAGGAGG GTGAGGCTGT


 


1251
GTTGGTGCGG CAGGTACCGG ACAATCCGGT AAACAGAACT GCATTGGCGG


 


1301
CTTTATCCGC CCACACCGTA CCATCTAAGG CTACGGGCAG GCATCAGGAA


 


1351
ATATTGGACG GCGCGTTGGA TGACGCGCTG GTTGAGCCCG ATTTCAATTC


 


1401
TCAGCTCAAC CCGATGGTGC GTCAGGCGGT TGCCGCACTT AATGCTTGCA


 


1451
ACAGCTACGA GGAGGCAGAT GCCGCACTGA ATGCGCTTTA TCCGAATTTG


 


1501
GACAACGCGA AACTGCGTAC CTATATGCAG CAGGCCTTGT TTATCAGCGA


 


1551
TATTTTGGGA CAAGACCATG CCCGCGCCTG A






This corresponds to the amino acid sequence <SEQ ID 2426; ORF 718-1.a>:










a718.pep




1
MEPIMAKKNN KTKIQKPEAA LQTDVAQITA TGRVIAEHPS NFITPQKMRA


 


51
LFEDAESGDI RAQHELFADI EERDSDIAAN MGTRKRALLT LNWRVAPPRN


 


101
ATPEEEKLSD QAYEMMDSLP TLEDLIMDLM DAVGHGFSAL EVEWVFSDGL


 


151
YLPRNFIHRP QSWFKWDKDN GLLLRTRENP EGEALWPLGW VVHTQKSRSV


 


201
QQARNGLFRT LSWLYMFKHY AVHDFAEFLE LYGMPIRIGK YGAGATKEEK


 


251
NTLLRAVAEI GHNAAGIMPE GMEIELHNAA NGMTSAGNPF LQMADWCEKS


 


301
AARLILGQTL TSGADGKSST NALGNIHNEI RRDLLVSDAK QVAQTITSQI


 


351
IGPFLQINYP HADPNRVPKF EFDTREPKDI AVFADAIPKL VDVGVQIPES


 


401
WVRDKLVIPD VQEGEAVLVR QVPDNPVNRT ALAALSAHTV PSKATGRHQE


 


451
ILDGALDDAL VEPDFNSQLN PMVRQAVAAL NACNSYEEAD AALNALYPNL


 


501
DNAKLRTYMQ QALFISDILG QDHARA*






a718/m718-1 99.0% identity in 526 aa overlap





g719.seq not found yet
g719.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2427>:









m719.seq




1
ATGGCAAACG GGAACATGAA ACTGTCGTTG GTGTTAACCG CCCGAGATGA


 


51
CGGAGCGAGA CGGCTACTGG CTGATACTCA ACGACAATTA GATCGTACCG


 


101
CGAAATCGCG GGCGCAACTT GAACGGCAAA GCCATACTTA TGCGTTGACC


 


151
GGCATCCGCT CAGAAAAACA GATTCAACGC GAAATCATGC TGACACAGGC


 


201
TGCGTTTAAC CGTTTGGCGC GCAGCGGCAA GGCATCACAA AATGATTTGG


 


251
CACGGGCGGC GGTCGCTACG CGTAACCGAA TTCGCGAGCT GAACGCGGAA


 


301
CTGAAACAGG GCACGGGATT TGCGGACAAG ATGGGAAAAA TCGGAAGATT


 


351
CGGTGCAGCT GCGGTGGCTG GTGGCGCGGC AGCGTATACG GTGCTTAAGC


 


401
CTGCTATGGA CAACAGAAAG CAGCTTGATG AGAACATCAA CCGCGTGTCC


 


451
AGACAGGCAT TTATTGAGGA TAACAGTAAA TCGGCAGCGT GGATTGCAAC


 


501
TGAAGGTGCG CAACAGATCA AGGATTTGGC ACTTGAACTT GTCGAGAAAA


 


551
ATGGCGGGAC CCACGATAAG GCTTTGGATT TAATCAGCGG CATGATGACC


 


601
ACCGGTCTGA ATTTTGCCCA AACCAAGAAT GAAGCGCAGG CGGCATATGC


 


651
TTTTGCACTT GCCTCAGAAG GCAGTGGCGA GGATACGGCA AAACTGATTA


 


701
AAACCCTGAA AGATGGCGGC ATGAGCGGTA AAGACCTGCA ACTCGGGCTT


 


751
GAGCACGTCT TGCAATCGGG TTTAGACGGC ACTTTCGAGG TGCGGGATAT


 


801
GGTTCGGGAG CTGCCGAGCC TGCTCTCTGC CGCGCAACAG GCAGGGATGA


 


851
ATGGTGTCGG CGGTTTGGAC TACCTGCTCT CACTCTTACA ATCTGCGGCG


 


901
AATAAATCGG GCAGTCCTGC CGAAGCGGCG ACTAATGTGC AAAATCTTTT


 


951
GAGTAAAACT CTGTCGCCTG ACACGATAGG TCGTCTGAAG AAGATGGCAA


 


1001
ATCCGAATGA CCCGAAGAAA GGTGTCGATT GGATAGGCTC GGTTGTGCAA


 


1051
GGCAAGCAAA ACGGCGAAAA CGCAGTGCAG GTGTTGTCCC GTCTTGCCGA


 


1101
TGCCATGCTA GTAAAGGATA AGCAATACCA AGATTATAAG AAACGCGCGG


 


1151
CTGCAGGCGA TAAGACGGCG GCGGAGCAGG CAAATATGCT TAAGGGCGCG


 


1201
CTTTTGGCGC AACTGCTGCC TGATTTGCAG GCAAAACAAG GTTTGCTGGC


 


1251
TGCAACGGAT ATGACGCAAA TCCGTGAATA TATGGCTTCG TTGGCTGGCG


 


1301
TAACGTTGGA TAACGGAAAA ATTGCTAAGA ACAACGAGGC GCGAATGTTG


 


1351
TCGGCAGCGG CGCAACAAGA GCAACAGGAA TCGCTGGCAA TGTTGCGGGA


 


1401
AAGTCTGACG GGAACATTGG TGGATATGGA AACCTCGTTT AAAAAGCTGG


 


1451
CAGCGGAATA CCCTAATGCC ACTCTAGCCC TGCAAGCATT GACGACGGCG


 


1501
GCAACAGCGG CGTCTGCCGC AATGTTATTA ACCGCCGGTG GCGGTAAAGG


 


1551
TGCAGGCTTT CTGAAAGATG TAGGTAGTAA AGCGTTGGGA TGGGGTAAGG


 


1601
CTTCCGCAGG CGGCGTGGCA GCAGGTGCCA CAGCGGCAGG CGGTAAGTTG


 


1651
CTGTCATGGG GAAAATCTGC CGGTAGCGGG CTCATGAATA ATCCAGCGTT


 


1701
AGTTAAACGG GCGGGTTTGT TAGGTATGTT GCTGTATTCC GAGTCTTTGG


 


1751
GTGACGGCAC ATTGCCAAAG GGTTTGCGTG GTACCAAGAC AACTCCTGAA


 


1801
ATGATTAATC GTCTGAAAAA CAACGGTATC CGATTTGAAC CTGCGCCGAA


 


1851
GCGGGAACAG GCGCGGGGTG GTGTCCCTCA GTATTTGGCT GCTCCGTCAG


 


1901
CGCAGCCTAC CGATAAGATG TTGTCTCCGT TGTTTTCAAC TCAGACGGCG


 


1951
GCGTATCAGG CAGCCATTCA GCAGCAGACG GCGGCGTATC AGGCAGCATT


 


2001
GGCGCAGGAT ACGGCTGCAG TTACAACAGG TTTGGCACAA GTGCAAAGTG


 


2051
CGATGGCGTC GGCAAGTCAG ACCATCAATA CCAATGTGAG CCTGAATATC


 


2101
GACGGACGTG TTATCGCGAA TGAGGTATCG CGGTATCAAG TGGCCATGTT


 


2151
CGGCCGTGGA GCGGGTCAAT AA






This corresponds to the amino acid sequence <SEQ ID 2428; ORF 719>:










m719.pep




1
MANGNMKLSL VLTARDDGAR RLLADTQRQL DRTAKSRAQL ERQSHTYALT


 


51
GIRSEKQIQR EIMLTQAAFN RLARSGKASQ NDLARAAVAT RNRIRELNAE


 


101
LKQGTGFADK MGKIGRFGAA AVAGGAAAYT VLKPAMDNRK QLDENINRVS


 


151
RQAFIEDNSK SAAWIATEGA QQIKDLALEL VEKNGGTHDK ALDLISGMMT


 


201
TGLNFAQTKN EAQAAYAFAL ASEGSGEDTA KLIKTLKDGG MSGKDLQLGL


 


251
EHVLQSGLDG TFEVRDMVRE LPSLLSAAQQ AGMNGVGGLD YLLSLLQSAA


 


301
NKSGSPAEAA TNVQNLLSKT LSPDTIGRLK KMANPNDPKK GVDWIGSVVQ


 


351
GKQNGENAVQ VLSRLADAML VKDKQYQDYK KRAAAGDKTA AEQANMLKGA


 


401
LLAQLLPDLQ AKQGLLAATD MTQIREYMAS LAGVTLDNGK IAKNNEARML


 


451
SAAAQQEQQE SLAMLRESLT GTLVDMETSF KKLAAEYPNA TLALQALTTA


 


501
ATAASAAMLL TAGGGKGAGF LKDVGSKALG WGKASAGGVA AGATAAGGKL


 


551
LSWGKSAGSG LMNNPALVKR AGLLGMLLYS ESLGDGTLPK GLRGTKTTPE


 


601
MINRLKNNGI RFEPAPKREQ ARGGVPQYLA APSAQPTDKM LSPLFSTQTA


 


651
AYQAAIQQQT AAYQAALAQD TAAVTTGLAQ VQSAMASASQ TINTNVSLNI


 


701
DGRVIANEVS RYQVAMFGRG AGQ*






a719.seq not found yet
a719.pep not found yet
g720.seq not found yet
g720.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2429>:









m720.seq




1
ATGAGCGGAT GGCATACCTT ATTGCAGGAC GCATCTTACA AGGGCGTCGG


 


51
CTTTGATATT GAGGTGGTGG ACGAGAGCAA CGGCAAGGCA TTGGCCGAGC


 


101
ATGCGCGGCC GTTTGTGCAG GGTATCGACC TTGAAGACAT GGGCATGACC


 


151
GGGCGGCAGG TGCAGATTAA TGCGGTGTTT TGGGGCAAGG GCTATGCAGG


 


201
CCGTCTGAAA AAGCTGCTGG ATGCGCTGGA GCAGCCGGGC GGCGGCGTGC


 


251
TGGTGCACCC TGTTTGGGGG CGGATGCACA ACATGATTGC GGCATCATGG


 


301
AGTTACCGAC ATGAGGCCGA TTATGTGGAT TATGCGGGCA TCGATATTAC


 


351
TTTCCGCGAG GCGGCCGAAG CGCAGGAAAT CTTTGTTTTT GAAAACGCCT


 


401
TTTTGGTCGA GCTTGAGGCG TTGATTGCTA ATATCGACAC CTACCGCGAG


 


451
GCGGCTATCG GCTTTGTTGA TGCGGTGTTG GCGGTGGATG CGGGCGTATC


 


501
AGCTTTATGG GGCAGCGCGC TGGGCATTTG GAGTGCGGCA TCGGGTACGT


 


551
TTGGCGCGGT GCGCCGTTTG TTTGATTTGG ACAAAATTGC CTTTCCCGAT


 


601
CGGGGCGGAT ACAGTGCAGC GGCGTTTAAA AACGGCTCGG CCAAGCTGTT


 


651
TGCGGATATA TCGGTCATGG TAGATACTGG CATACGCCGT GAGGCGGGTT


 


701
TGGCCGATAA TGCCATGCAC CATGCCGGTT GGTCGCCGCG ACAGCGGTTT


 


751
GACGGGGCTG CGGCTGTTGC CGACCGCGCC GCCGCTATCC CTGATAATTT


 


801
GCTGACCGGC CGCTTTTCAG ACGGCCTGCA AAACCGCCTG AACCGGTTAA


 


851
CCGCCAAACA GGTGCAGCCG GTAGCGCAGG CGGTGCGCCT GTTATCCACG


 


901
TCATCGCTGT TGTCGGTGGC AACGGCATTA ATCGAGGCGC ATGGCGAAGA


 


951
GATGACCGCG CCCGATTTGA TTGAGGTTAA CCGCGCCATG CGCCGCCGTA


 


1001
TGCAGGCCGA GATTGCCGCC TTGCGGGCGG TGCAGACGGC TGCTGCCGAG


 


1051
TCTGGTGGGC TGACGGCCAA CGCCGTGTAT ACCGAGGCTT ACCAAACGGC


 


1101
AGAATCCCTG CGCGCGGCGG CAGGCCGTCT GAATGCGTTG GTTGCGGCGG


 


1151
TCATCAACCA AAAGCCGCCG CTGATTGTGC GCCAAGCCCC AATCGACGGT


 


1201
ACGATACACC AAATCGCCCA CGAGTTTTAC GGCGATATAG CCCGCGCAGC


 


1251
AGAGCTGGTG CGGCTCAATC CCCATATCCA CCACCCCGCG TTTATCAAGC


 


1301
GCGGCACTTT GGTCAACAGC TATGCAAAAT AA






This corresponds to the amino acid sequence <SEQ ID 2430; ORF 720>:










m720.pep




1
MSGWHTLLQD ASYKGVGFDI EVVDESNGKA LAEHARPFVQ GIDLEDMGMT


 


51
GRQVQINAVF WGKGYAGRLK KLLDALEQPG GGVLVHPVWG RMHNMIAASW


 


101
SYRHEADYVD YAGIDITFRE AAEAQEIFVF ENAFLVELEA LIANIDTYRE


 


151
AAIGFVDAVL AVDAGVSALW GSALGIWSAA SGTFGAVRRL FDLDKIAFPD


 


201
RGGYSAAAFK NGSAKLFADI SVMVDTGIRR EAGLADNAMH HAGWSPRQRF


 


251
DGAAAVADRA AAIPDNLLTG RFSDGLQNRL NRLTAKQVQP VAQAVRLLST


 


301
SSLLSVATAL IEAHGEEMTA PDLIEVNRAM RRRMQAEIAA LRAVQTAAAE


 


351
SGGLTANAVY TEAYQTAESL RAAAGRLNAL VAAVINQKPP LIVRQAPIDG


 


401
TIHQIAHEFY GDIARAAELV RLNPHIHHPA FIKRGTLVNS YAK*






The following partial DNA sentience was identified in N. meningitidis <SEQ ID 2431>:









a720.seq (partial)










1
GGCCTGCAAA ACCGCCTGAA CCGGTTAACC GCCAAACAGG TGCAGCCGGT



 


51
AGCGCAGGCG GTGCGCCTGT TATCCACGTC ATCGCTGTTG TCGGTGGCAA


 


101
CGGCATTAAT CGAGGCGCAT GGCGAAGAGA TGACCGCGCC CGATTTGATT


 


151
GAGGTTAACC GCGCCATGCG CCGCCGTATG CAGGCCGAGA TTGCCGCCTT


 


201
ACGGGCGGTG CAGACGGCTG CTGCCGAGTC TGGTGGGCTG ACGGCCAACG


 


251
CCGTGTATAC CGAGGCTTAC CAAACGGCAG AATCCCTGCG CGCGGCGGCA


 


301
GGCCGTCTGA ATGCGTTGGT TGCGGCGGTC ATCAACCAAA AGCCGCCGCT


 


351
GATTGTGCGC CAAGCCCCAA TCGACGGTAC GATACACCAA ATCGCCCACG


 


401
AGTTTTACGG CGATATAGCC CGCGCAGCAG AGCTGGTGCG GCTCAATCCC


 


451
CATATCCACC ACCCCGCGTT TATCAAGCGC GGCACTTTGG TCAACAGCTA


 


501
TGCAAAATAA






This corresponds to the amino acid sequence <SEQ ID 2432; ORF 720.a>:









a720.pep (partial)










1
GLQNRLNRLT AKQVQPVAQA VRLLSTSSLL SVATALIEAH GEEMTAPDLI



 


51
EVNRAMRRRM QAEIAALRAV QTAAAESGGL TANAVYTEAY QTAESLRAAA


 


101
GRLNALVAAV INQKPPLIVR QAPIDGTIHQ IAHEFYGDIA RAAELVRLNP


 


151
HIHHPAFIKR GTLVNSYAK*






m720/a720 100.0% identity in 169 aa overlap





g721.seq not found

g721.pep not found

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2433>:










m721.seq




1
ATGTCCAAAA ATGCACAAAA AACCCTACTT GCCGTGTGCA GTTTCGAGGT


 


51
GCAGCCAAAA GACGGGCGAA TCCAACTGCT GCCATATGGC GAATTTCGCG


 


101
CAGTAGACGG TCGTCCGACT GATGTCCCTG CGTGGTATCT GACCGAAGAA


 


151
AACGGTCATG ATGTCGCGTT GTTGGCCAAC AGCTCGCGCA ATCAGTTGGT


 


201
TGTCGATTAT GAACACCAGA CGCTCTACAA AGAGAAAAAC GGACAACCTG


 


251
CACCTGCCGC CGGTTGGATG CGTTGGCTGG AGTTCACGCC TAAAGGCATG


 


301
TTTGCCGAAG TGGAGTGGAC GGACAAGGCG GCTGCGGCAA TTGCCGCAAA


 


351
AGAGTATCGC TACATCTCTG CTGTGTTTTC CTATGACACA AAGGGATATG


 


401
TAAGCAAAAT TTTTCACGCC GCGCTGACAA ATTTCCCCGC GTTGGACGGT


 


451
ATGGACGAGG TGCTGGCGGC AGCGTCGGCG CAAATTTTAA AACCGGAAAC


 


501
GGAGCAAAAC CCTATGAAAG AGTTGTTACA GCAACTGTTC GACCTGCCTG


 


551
ATGCGGGCGA AGAAGAACTG AAGGCGGCAT TGTCCGCGCT CGTGGAAGCC


 


601
AAGCCGAAAG ACGTGGCATT GTCTGCCGAC GTGTTCGCGC AGCTGGCGGA


 


651
AAAAGACAGC CGCATCGCGG CATTGACGGC GCAAACCGCC AAGCCTGATT


 


701
TGACTAAATA CGCGCCTATC TCAGTGGTTC AAGAGCTGCA AAGCAAAGTC


 


751
GCCGCGCTGA CTGCCAAGCA GGAAGCAGAC AAAGGCAACG AATTGATTAC


 


801
CGCCGCGCTG ACTTCAGGCA AATTGCTGCC TGCTCAGAAG GAGTGGGCAA


 


851
AAGGCGTATT GAAACAGCCG GGCGGCTTGG CATTTTTGAC CGGCTTTATT


 


901
GAAAACGCCC AGCCGGTCGC TGCACTGGCA GGCTCGCAAA CGGGCGGCAA


 


951
AGCACCCGAC GAACGCGTCG CCGCACTGAC TGCGGAAGAG GCAGCCGCAG


 


1001
CAAAAATGCT GGGCATGTCC GGCGAAGAAT TTGTAAAAAT CAAAGAAAGC


 


1051
GAAGGTAAGT AA






This corresponds to the amino acid sequence <SEQ ID 2434; ORF 721>:










m721.pep




1
MSKNAQKTLL AVCSFEVQPK DGRIQLLPYG EFRAVDGRPT DVPAWYLTEE


 


51
NGHDVALLAN SSRNQLVVDY EHQTLYKEKN GQPAPAAGWM RWLEFTPKGM


 


101
FAEVEWTDKA AAAIAAKEYR YISAVFSYDT KGYVSKIFHA ALTNFPALDG


 


151
MDEVLAAASA QILKPETEQN PMKELLQQLF DLPDAGEEEL KAALSALVEA


 


201
KPKDVALSAD VFAQLAEKDS RIAALTAQTA KPDLTKYAPI SVVQELQSKV


 


251
AALTAKQEAD KGNELITAAL TSGKLLPAQK EWAKGVLKQP GGLAFLTGFI


 


301
ENAQPVAALA GSQTGGKAPD ERVAALTAEE AAAAKMLGMS GEEFVKIKES


 


351
EGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2435>:










a721.seq




1
ATGTCCAAAA ATGCACAAAA AACCCTACTT GCCGTGTGCA GTTTCGAGGT


 


51
GCAGCCAAAA GACGGGCGAA TCCAACTGCT GCCATATGGC GAATTTCGCG


 


101
CAGTAGACGG TCGTCCGACT GATGTCCCTG CGTGGTATCT GACCGAAGAA


 


151
AACGGTCATG ATGTCGCGTT GTTGGCCAAC AGCTCGCGCA ATCAGTTGGT


 


201
TGTCGATTAT GAACACTAGA CGCTCTACAA AGAGAAAAAC GGACAACCTG


 


251
CACCTGCCGC CGGTTGGATG CGTTGGCTGG AGTTCACGCC TAAAGGCATG


 


301
TTTGCCGAAG TGGAGTGGAC GGACAAGGCG GCTGCGGCAA TTGCCGCAAA


 


351
AGAGTATCGC TACATCTCTG CTGTGTTTTC CTATGACACA AAGGGATATG


 


401
TAAGCAAAAT TTTTCACGCC GCGCTGACAA ATTTCCCCGC GTTGGACGGT


 


451
ATGGACGAGG TGCTGGCGGC AGCGTCGGCG CAAATTTTAA AACCGGAAAC


 


501
GGAGCAAAAC CCTATGAAAG AGTTGTTACA GCAACTGTTC GGTCTGCCTG


 


551
ATGCGGGCGA AGAAGAACTG AAGGCGGCAT TGTCCGCGCT CGTGGAAGCC


 


601
AAGCCGAAAG ACGTGGCATT GTCTGCCGAC GTGTTCGCGC AGCTGGCGGA


 


651
AAAAGACAGC CGCATCGCGG CATTGACGGC GCAAACCGCC AAGCCTGATT


 


701
TGACTAAATA CGCGCCTATC TCAGTGGTTC AAGAGCTGCA AAGCAAAGTC


 


751
GCCGCGCTGA CTGCCAAGCA GGAAGCAGAC AAAGGCAACG AATTGATTAC


 


801
CGCCGCGCTG ACTTCAGGCA AATTGCTGCC TGCTCAGAAG GAGTGGGCAG


 


851
AAGGCGTATT GAAACAGCCG GGCGGCTTGG CATTTTTGAC CGGCTTTATT


 


901
GAAAACGCCC AGCCGGTCGC TGCACTGGCA GGCTCGCAAA CGGGCGGTAA


 


951
AGCACCCGAC GAACGCGTCG CCGCACTGAC TGCGGAAGAG GCAGCCGCAG


 


1001
CAAAAATGCT GGGCATGTCC GGCGAAGAAT TTGTAAAAAT CAAAGAAAGC


 


1051
GAAGGTAAGT AA






This corresponds to the amino acid sequence <SEQ ID 2436; ORF 721.a>:










a721.pep




1
MSKNAQKTLL AVCSFEVQPK DGRIQLLPYG EFRAVDGRPT DVPAWYLTEE


 


51
NGHDVALLAN SSRNQLVVDY EH*TLYKEKN GQPAPAAGWM RWLEFTPKGM


 


101
FAEVEWTDKA AAAIAAKEYR YISAVFSYDT KGYVSKIFHA ALTNFPALDG


 


151
MDEVLAAASA QILKPETEQN PMKELLQQLF GLPDAGEEEL KAALSALVEA


 


201
KPKDVALSAD VFAQLAEKDS RIAALTAQTA KPDLTKYAPI SVVQELQSKV


 


251
AALTAKQEAD KGNELITAAL TSGKLLPAQK EWAEGVLKQP GGLAFLTGFI


 


301
ENAQPVAALA GSQTGGKAPD ERVAALTAEE AAAAKMLGMS GEEFVKIKES


 


351
EGK*






a721/m721 99.2% identity in 353 aa overlap





g722.seq not found yet
g722.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2437>:









m722.seq




1
GTGTTTGAAA CGCCGACATT TGAGCAAATC CGCGAGCGTA TCCTGCGCGA


 


51
TACCAAAAGC CTGTGGCCGG ATGCCGATAT CAGCCCCGAC AGCGACCATT


 


101
ATGTGCACGC CAGCCGTTTG GCCAGCTGCG CCGAAGGGCA ATATGCGCAT


 


151
CAAAGCTGGA TTGTGCGGCA GATTTTCCCT GATACCGCCG ACCGCGAGTA


 


201
TTTGGAGCGG CATGCCTCCA TGCGCGGCTT GAGCCGCCGC AATCCTACCA


 


251
CGGCCAGCGG CACGCTGACC GTAAGCGGTA TTGCGCAATC CATGCTTTCA


 


301
GACGACCTGC AAGTGCGTAT CGGCCAGCGT TTTTACCGCA CTACCGCCCG


 


351
CGCCGTTATC GGCAGCGGCG GCACGGCGGA AATACCGGCA ATCGCCGACG


 


401
AGCCGGGCGC GGCCGCCAAT GTGGGCGACG GCGAGGCGCA ACTGATGGCC


 


451
GCCCCCGCCG GTGTGGCCAC CGAATGCCGC CTTACCGTAC AAGGCGGCAC


 


501
CGACCGAGAA AGCGATGCCT CACTGCTGGC GCGTCTGTTG GAAATCATCC


 


551
GCCGACCGCC CGCAGGCGGC AACCGTTACG ACTATAAAAA CTGGGCGTTG


 


601
AGTGTTGACG GCGTAACCAG CGCATATGTT TATCCGCTGC GCCGCGGCTT


 


651
GGGTACGGTG GATATTGCCA TTACCTCCGC CGACGGTGTG TCGTCGGAAG


 


701
AAACTGTGCG CCGCGTACAG GCTTATATCG ACGAGATGCG CCCGGTAACG


 


751
GCAAAAAATG CGCTGGTACT CAAGCCAACC GTAACGGCGG TGCCTGTTAC


 


801
CGTGCAAGTC AAGCTCGACG GTATCGACTT GGACGAGGCC AAGCGCCGCA


 


851
TACGGACGGC CCTAAAAGAA TATTTCGACA CCCTGATCCC CGGCGACGGC


 


901
CTGACTGTGT CGCAAATCGA GGCTGCTATC AGCAATGTGG ATGGTGTGAT


 


951
CGACCGCCGT CTGACTGCGC CGACGGCCAA CCGTGCCGCC GATACGGTTA


 


1001
ACCGCATCGA GTGGTTTAAA GCGGGCGCGA TTAATGTAAC GGAGATGCCG


 


1051
TCATGA






This corresponds to the amino acid sequence <SEQ ID 2438; ORF 722>:










m722.pep




1
VFETPTFEQI RERILRDTKS LWPDADISPD SDHYVHASRL ASCAEGQYAH


 


51
QSWIVRQIFP DTADREYLER HASMRGLSRR NPTTASGTLT VSGIAQSMLS


 


101
DDLQVRIGQR FYRTTARAVI GSGGTAEIPA IADEPGAAAN VGDGEAQLMA


 


151
APAGVATECR LTVQGGTDRE SDASLLARLL EIIRRPPAGG NRYDYKNWAL


 


201
SVDGVTSAYV YPLRRGLGTV DIAITSADGV SSEETVRRVQ AYIDEMRPVT


 


251
AKNALVLKPT VTAVPVTVQV KLDGIDLDEA KRRIRTALKE YFDTLIPGDG


 


301
LTVSQIEAAI SNVDGVIDRR LTAPTANRAA DTVNRIEWFK AGAINVTEMP


 


351
S*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2439>:










a722.seq




1
GTGTTTGAAA CGCCGACATT TGAGCAAATC CGCGAGCGTA TCCTGCGCGA


 


51
TACCAAAAGC CTGTGGCCGG ATGCCGATAT CAGCCCCGAC AGCGACCATT


 


101
ATGTGCACGC CAGCCGTTTG GCCAGCTGCG CCGAAGGGCA ATATGCGCAT


 


151
CAAAGCTGGA TTGTGCGGCA GATTTTCCCT GATACCGCCG ACCGCGAGTA


 


201
TTTGGAGCGG CATGCCTCCA TGCGCGGCTT GCGCCGCCGC AATCCTACCA


 


251
CGGCCAGCGG CACGCTGACC GTAAGCGGTA TTGCGCAATC CATGCTTTCA


 


301
GACGGCCTGC AAGTGCGTAT CGGCCAGCGT TTTTACCGCA CTACCGCCCG


 


351
CGCCGTTATC GGCAGCGGCG GCACGGCGGA AATACCGGCA ATCGCCGACG


 


401
AGCCGGGCGC GGCCGCCAAT GTGCGCGACG GCGAGGCGCA ACTGATGGCC


 


451
GCCCCCGCCG GTGTGTCCAC CGAATGCCGC CTTACCGTAC AAGGCGGCAC


 


501
CGACCGAGAA AGCGATGCCT CACTGCTGGC GCGTCTGTTG GAAATCATCC


 


551
GCCGACCGCC CGCAGGCGGC AACCGTTACG ACTATAAAAA CTGGGCGTTG


 


601
AGTGTTGACG GCGTAACCAG CGCATATGTT TATCCGCTGC GCCGCGGCTT


 


651
GGGTACGGTG GATATTGCCA TTACCTCCGC CGACGGTGTG CCATCGGAAG


 


701
AAACTGTGCG CCGCGTACAG GCTTATATCG ACGAGATGCG CCCGGTAACG


 


751
GCAAAAAATG CGCTGGTACT CAAGCCAACC GTAACGGCGG TGCCTGTTAC


 


801
CGTGCAAGTC AAGCTCGACG GCATCGACTT GGACGAGGCC AAGCGCCGCA


 


851
TACGGACGGC CCTAAAAGAA TATTTCGACA CCCTGATCCC CGGCGACGGC


 


901
CTGACTGTGT CGCAAATCGA GGCGGCTATC AGCAATGTGG ATGGTGTGAT


 


951
CGACCTCCGT CTGACTGCGC CGACGGCCAA CCGTGCCGCC GATACGGTTA


 


1001
ACCGCATCGA GTGGTTTAAA GCGGGCGCGA TTAATGTAAC GGAGATGCCG


 


1051
TCATGA






This corresponds to the amino acid sequence <SEQ ID 2440; ORF 722.a>:










a722.pep




1
VFETPTFEQI RERILRDTKS LWPDADISPD SDHYVHASRL ASCAEGQYAH


 


51
QSWIVRQIFP DTADREYLER HASMRGLRRR NPTTASGTLT VSGIAQSMLS


 


101
DGLQVRIGQR FYRTTARAVI GSGGTAEIPA IADEPGAAAN VRDGEAQLMA


 


151
APAGVSTECR LTVQGGTDRE SDASLLARLL EIIRRPPAGG NRYDYKNWAL


 


201
SVDGVTSAYV YPLRRGLGTV DIAITSADGV PSEETVRRVQ AYIDEMRPVT


 


251
AKNALVLKPT VTAVPVTVQV KLDGIDLDEA KRRIRTALKE YFDTLIPGDG


 


301
LTVSQIEAAI SNVDGVIDLR LTAPTANRAA DTVNRIEWFK AGAINVTEMP


 


351
S*






g723.seq not found yet
g723.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2441>:









m723.seq




1
ATGCGACCCA AGCCCCGTTT CAGACGGTCT GTTATCGCTT GCTCAATATC


 


51
AGTGATCACG CCCGAACACC TTATTTTTAC CGTTTACAAA CACAATACCG


 


101
TCTTCGCCCG CGGCCACTTC TTCGCCGCTA TCATCCACGC CCAGCTGCAC


 


151
TTCGCCTTTG GCCATAGCAC GCAGCAGGTC GAGCACGTCG ATTTTGTAGC


 


201
GGTTGCGGAT TTCGTCGGTA ATCAACACGC CCTGAGCCGC CGTCAGACGG


 


251
TAGCGGGCAA TGTCGCAGCA AAGGCGCACC AAGATGGGCG GCAGATCCTC


 


301
AAAAGGTCGT CTGAACCGCC CCAGATACGC GTCGATTTCG GCAGTGGCGT


 


351
CCACCAGCGC GGTTTGTGCG ACCTCGCGGT CAATCAGCCC CTCGTTGTTG


 


401
CGGTCGGTGA GCTGCAAGAC TTCCAGCTCA CCGAAACGCG CAACCATATC


 


451
CTCAACCGTC GCGTATGCCA TTACTCGACC GCCTTGCGTT GCAGCATAGG


 


501
CTCGGCGCAG ATTGCCTTCC ACACCGCTTC GCCGACTTCG GCGCGCTTCA


 


551
CTTCGCGCCA GCCGCCGTCA AACAGCAGGC CGCCGCGCCA AAATTCTTTG


 


601
CCGTCTGCGC CGGTACTGAC GAGCATCACA TCGCGGCTGT CCGCCAAAGC


 


651
GTCGGCGGCA CGTTGCGTAT GCTGCACTTT GAGTTCGGCA AGTTCGGCGG


 


701
ACAGTGCCTT TTTGTCGTCT TCGGCTTTTT CCAAGGCTGT GGTCAGCATT


 


751
TCGACATCGT TTCGGGCGGC GGCAAGCTCT GCCTGCACGG CGTCCAATTC


 


801
GGCTTTGATG TCTTCAAACG ACGGGGCGGC GGTTTCGGCG GTTTCTGGTT


 


851
TGTTGTTGGT TTTTGCCATG ATGACTCCTT GTTTCAGACG GCGGCGGATT


 


901
CGCATTTGA






This corresponds to the amino acid sequence <SEQ ID 2442; ORF 723>:










m723.pep




1
MRPKPRFRRS VIACSISVIT PEHLIFTVYK HNTVFARGHF FAAIIHAQLH


 


51
FAFGHSTQQV EHVDFVAVAD FVGNQHALSR RQTVAGNVAA KAHQDGRQIL


 


101
KRSSEPPQIR VDFGSGVHQR GLCDLAVNQP LVVAVGELQD FQLTETRNHI


 


151
LNRRVCHYST ALRCSIGSAQ IAFHTASPTS ARFTSRQPPS NSRPPRQNSL


 


201
PSAPVLTSIT SRLSAKASAA RCVCCTLSSA SSADSAFLSS SAFSKAVVSI


 


251
STSFRAAASS ACTASNSALM SSNDGAAVSA VSGLLLVFAM MTPCFRRRRI


 


301
RI*






a723.seq not found yet
a723.pep not found yet
g724.seq not found yet
g724.pep not found yet
The following partial DNA sequence, shown with its encoded amino acid sequence, was identified in N. meningitidis <SEQ ID 2443>:




This corresponds to the amino acid sequence <SEQ ID 2444; ORF 724>:










m724.pep




1
MSLSKLAKKT AQTAKNIGET LRAAFRGKIT LVVSSEPIQR VQLSGLADET


 


51
LQDLEHLQEY GFASHPPDGS EAVVIPLGGN TSHGVIVCSQ HGSYRIKNLK


 


101
PGETAIFNHE GAKIVIKQGK IIEADCDVYR VNCKQYEVNA ATDAKFNAPL


 


151
VETSAVLTAQ GQINGNGGMA VEGGDGATFS GDVNQTGGSF NTDGDVVAGN


 


201
ISLRQHPHTD SIGGKTLPAE PA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2445>:










a724.seq




1
ATGAGTTTGA GTAAATTGGC GAAAAAAACG GCACAAACTG CTAAAAATAT


 


51
CGGCGAAACC CTGCGCGCGG CCTTTCGGGG AAAAATCACG CTGGTGGTGT


 


101
CGTCCGAGCC GATACAGCGC GTGCAGTTGA GCGGCTTGGC CGACGAAACC


 


151
CTGCAAGACC TTGAACATTT GCAGGAATAC GGCTTTGCCA GCCATCCGCC


 


201
CGACGGCAGC GAAGCGGTAG TGATACCGCT GGGCGGCAAT ACTTCGCACG


 


251
GTGTGATTGT GTGCAGCCAG CACGGCAGCT ACCGCATCAA AAACCTTAAG


 


301
CCCGGCGAGA CGGCGATTTT TAATCATGAG GGTGCAAAAA TCGTGATTAA


 


351
GCAAGGCAAA ATCATTGAGG CCGATTGCGA CGTGTACCGG GTTAACTGCA


 


401
AACAATACGA GGTTAATGCG GCCACGGATG CCAAATTTAA CGCTCCGTTG


 


451
GTGGAGACCA GTGCAGTGTT GACGGCGCAA GGCCAAATCA ACGGCAACGG


 


501
CGGCATGGCC GTCGAGGGCG GCGACGGAGC CACCTTTAGC GGCGATGTTA


 


551
ACCAAACGGG CGGCAGCTTT AACACCGACG GCGACGTGGT GGCCGGCAAT


 


601
ATATCGTTGC GCCAGCACCC GCATACCGAC AGCATCGGCG GCAAAACCTT


 


651
ACCGGCGGAA CCGGCATAG






This corresponds to the amino acid sequence <SEQ ID 2446; ORF 724.a>:










a724.pep




1
MSLSKLAKKT AQTAKNIGET LRAAFRGKIT LVVSSEPIQR VQLSGLADET


 


51
LQDLEHLQEY GFASHPPDGS EAVVIPLGGN TSHGVIVCSQ HGSYRIKNLK


 


101
PGETAIFNHE GAKIVIKQGK IIEADCDVYR VNCKQYEVNA ATDAKFNAPL


 


151
VETSAVLTAQ GQINGNGGMA VEGGDGATFS GDVNQTGGSF NTDGDVVAGN


 


201
ISLRQHPHTD SIGGKTLPAE PA*






a724/m724 100.0% identity in 222 aa overlap





g725.seq not found yet
g725.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2447>:









m725.seq




1
ATGGTGCGCA CGGTTAAAAG CTACAACGGC GAGGCCGACG ATTTGGCGGG


 


51
GCAAATCCAT ACGCTGCCTG CGGTTTGGGT AACGTATGGC GGCAGCAAAG


 


101
TTGAGCCTGC CAGCACCGGC GGCGTATGCG GACGTTATCA GGATACCGCC


 


151
GAATTTGTGG TGATGGTGGC GGCCCGCAAT CTGCGCAACG AGCAGGCGCA


 


201
GCGGCAAGGC GGCATCGACA GCCGCGAAAT CGGCAGCAAC GATTTAATCC


 


251
GCGCTGTTCG CCGCCTGCTT GACGGCCAGC GGCTCGGTTT TGCCGATAGC


 


301
CGCGGCTTGG TGCCCAAAGC GGTGCGCGCG ATTGCCAATC ATGTGCTGGT


 


351
GCAAAACGCC GCAGTAAGCA TATATGCGGT TGAGTATGCC ATCCGCTTTA


 


401
ACACCTGCGG GTTGGAAAAT GACCGCTACC CCGAACGCAC CGACAATCCC


 


451
GACGACCCCA ACCATATCTT TACCAAGTAT CAGGGTACAT TGAGCGAGCC


 


501
GTGGCCTGAT TTCGAGGGGT TGGACGGCAA AATTTACGAC CCGCAATCCG


 


551
CCGATGAAAT ACCTGTAAAC CTAACCCTTA AGGATAAGCA ATGA






This corresponds to the amino acid sequence <SEQ ID 2448; ORF 725>:










m725.pep




1
MVRTVKSYNG EADDLAGQIH TLPAVWVTYG GSKVEPASTG GVCGRYQDTA


 


51
EFVVMVAARN LRNEQAQRQG GIDSREIGSN DLIRAVRRLL DGQRLGFADS


 


101
RGLVPKAVRA IANHVLVQNA AVSIYAVEYA IRFNTCGLEN DRYPERTDNP


 


151
DDPNHIFTKY QGTLSEPWPD FEGLDGKIYD PQSADEIPVN LTLKDKQ*






a725.seq not found yet
a725.pep not found yet
g726.seq not found yet
g726.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2449>:









m726.seq




1
ATGACCATCT ATTTCAAAAA CGGCTTTTAC GACGACACAT TGGGCGGCAT


 


51
CCCCGAAGGC GCGGTTGCCG TCCGCGCCGA AGAATACGCC GCCCTTTTGG


 


101
CAGGACAGGC GCAGGGCGGG CAGATTGCCG CAGATTCCGA CGGCCGCCCC


 


151
GTTTTAACCC CGCCGCGCCC GTCCGATTAC CACGAATGGG ACGGCAAAAA


 


201
ATGGAAAATC AGCAAAGCCG CCGCCGCCGC CCGTTTCGCC AAACAAAAAA


 


251
CCGCCTTGGC ATTCCGCCTC GCGGAAAAGG CGGACGAACT CAAAAACAGC


 


301
CTCTTGGCGG GCTATCCCCA AGTGGAAATC GACAGCTTTT ACAGGCAGGA


 


351
AAAAGAAGCC CTCGCGCGGC AGGCGGACAA CAACGCCCCG ACCCCGATGC


 


401
TGGCGCAAAT CGCCGCCGCA AGGGGCGTGG AATTGGACGT TTTGATTGAA


 


451
AAAGTTATCG AAAAATCCGC CCGCCTGGCT GTTGCCGCCG GCGCGATTAT


 


501
CGGAAAGCGT CAGCAGCTCG AAGACAAATT GAACACCATC GAAACCGCGC


 


551
CCGGATTGGA CGCGCTGGAA AAGGAAATCG AAGAATGGAC GCTAAACATC


 


601
GGCTGA






This corresponds to the amino acid sequence <SEQ ID 2450; ORF 726>:










m726.pep




1
MTIYFKNGFY DDTLGGIPEG AVAVRAEEYA ALLAGQAQGG QIAADSDGRP


 


51
VLTPPRPSDY HEWDGKKWKI SKAAAAARFA KQKTALAFRL AEKADELKNS


 


101
LLAGYPQVEI DSFYRQEKEA LARQADNNAP TPMLAQIAAA RGVELDVLIE


 


151
KVIEKSARLA VAAGAIIGKR QQLEDKLNTI ETAPGLDALE KEIEEWTLNI


 


201
G*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2451>:










a726.seq




1
ATGACCATCT ATTTCAAAAA CGGCTTTTAC GACGACACCT TGGGCAGCAT


 


51
CCCCGAAGGC GCGGTTGCCG TCCGCGCCGA AGAATACGCC GCCCTTTTGG


 


101
CAGGACAGGC GCAGGGCGGG CAGATTGCCG CAGATTCCGA CGGCCGCCCC


 


151
GTTTTAACCC CGCCGCGCCC GTCCGAATAC CACGAATGGG ACGGCAAGAA


 


201
ATGGGAAATC GGCGAAGCCG CTGCCGCCGC CCGTTTCGCC GAACAAAAAA


 


251
CCGCCACGGC ATTCCGCCTC GCGGCAAAGG CGGACGAACT CAAAAACAGC


 


301
CTCTTGGCGG GCTATCCCCA AGTGGAAATC GACAGCTTTT ACAGGCAGGA


 


351
AAAAGAAGCC CTCGCGCGGC AGGCGGACAA CAACGCCCCG ACCCCGATGC


 


401
TGGCGCAAAT CGCCGCCGCA AGGGGCGTGG AATTGGACGT TTTGATTGAA


 


451
AAAGTTGTCG AAAAATCCGC CCGCCTGGCC GTTGCCGCCG GCGCGATTAT


 


501
CGGAAAGCGG CAGCAGCTCG AAGACAAATT GAACACCATC GAAACCGCGC


 


551
CAGGATTGGA CGCGCTGGAA AAGGAAATCG AAGAATGGAC GCTAAACATC


 


601
GGCTGA






This corresponds to the amino acid sequence <SEQ ID 2452; ORF 726.a>:










a726.pep




1
MTIYFKNGFY DDTLGSIPEG AVAVRAEEYA ALLAGQAQGG QIAADSDGRP


 


51
VLTPPRPSEY HEWDGKKWEI GEAAAAARFA EQKTATAFRL AAKADELKNS


 


101
LLAGYPQVEI DSFYRQEKEA LARQADNNAP TPMLAQIAAA RGVELDVLIE


 


151
KVVEKSARLA VAAGAIIGKR QQLEDKLNTI ETAPGLDALE KEIEEWTLNI


 


201
G*






a726/m726 95.5% identity in 201 aa overlap





g727.seq not found yet
g727.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2453>:









m727.seq




1
ATGAATCTCG TGAAACTGCT GGCGAATAAC TGGCAACCGA TTGCCATTAT


 


51
CGCGCTTGTC GGCACGGGCT TGGCTGTGTC GCACCATCAA GGCTACAAGT


 


101
CGGCATTTGC GAAGCAGCAG GCGGTCATCG ACAAGATGGA GCGCGACAAG


 


151
GCGCAAGCCC TGCTGTTGTC GGCTCAAAAC TATGCGCGCG AACTGGAACT


 


201
GGCACGCGCG GAAGCTAAAA AATATGAAGT CAAGGCGCAC GCTGTCGGCA


 


251
TGGCTTTGGC GAAAAAACAG GCGGAAGTCA GCCGTCTGAA AACGGAAAGA


 


301
GACCTTTGCA AAATTCCTTT CCCTCCCGAC AGCCGAAACC CAAACACAGG


 


351
TTTTCGGCTG TTTTCGCCCC AAATACCGCC TAATTTTACC CAAATACCCC


 


401
CTTAA






This corresponds to the amino acid sequence <SEQ ID 2454; ORF 727>:










m727.pep




1
MNLVKLLANN WQPIAIIALV GTGLAVSHHQ GYKSAFAKQQ AVIDKMERDK


 


51
AQALLLSAQN YARELELARA EAKKYEVKAH AVGMALAKKQ AEVSRLKTER


 


101
DLCKIPFPPD SRNPNTGFRL FSPQIPPNFT QIPP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2455>:










a727.seq




1
ATGAATCTCG TGAAACTGCT GGCGAATAAC TGGCAACCGA TTGCCATCAT


 


51
CGCGCTTGTC GGCACGGGTT TGGCGGTGTC GCACCATCAA GGCTACAAGT


 


101
CGGCTTTTGC GAAGCAGCAG GCGGTCATTG AGAAAATGAA GCGCGACAAG


 


151
GCGCAAGCCC TGCTGTTGTC GGCTCAAAAC TACGCCCGCG AACTGGAACA


 


201
GGCGCGTGCG GAAGCTAAAA AATATGAAGT CAAGGCGCAC GCCGTCGGCA


 


251
TGGCTTTGGC GAAAAAACAG GCGGAAGTCA GCCGTCTGAA AACGGAAAAT


 


301
AAAAAGGAAA TCGAAAATGT CCTTACTCAA GACCGTAAAA ATGCAGGCGG


 


351
CGGTTGTATT GACGGCTTTG GCCATCACGG CTTGCAGCTC TACAAGCGCG


 


401
CCCTCGGCTA CGGAAATTAA






This corresponds to the amino acid sequence <SEQ ID 2456; ORF 727.a>:










a727.pep




1
MNLVKLLANN WQPIAIIALV GTGLAVSHHQ GYKSAFAKQQ AVIEKMKRDK


 


51
AQALLLSAQN YARELEQARA EAKKYEVKAH AVGMALAKKQ AEVSRLKTEN


 


101
KKEIENVLTQ DRKNAGGGCI DGFGHHGLQL YKRALGYGN*






a727/m727 83.2% identity in 119 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2457>:










g728.seq




1
ATGTTTAAAA AATTCAAACC GGTACTGTTG TCATTTTTTG CACTTGTATT


 


51
TGCCTTTTGG CTGGGAACAG GTATTGCCTA TGAGATTAAT CCGCGTTGGT


 


101
TTTTGAGCGA TACGGCAACT GAAGTACCTG AAAATCCGAA TGCTTTTGTG


 


151
GCGAAACTTG CCCGCCTGTT CCGAAATGCC GACAGGGCGG TTGTCATCGT


 


201
GAAGGAATCG ATGAGGACGG AGGAAAGCCT TGCCGGAGCT GTGGATGACG


 


251
GTCCGTTGCA GTCGGAGAAG GATTATCTCG CGCTCGCTAT CCGGCTCAGT


 


301
CGTTTGAAAG AAAAGGCGAA ATGGTTTCAC GTAACGGAGC AGGAACATGG


 


351
GGAAGAGGTT TGGCTGGATT ACTATATCGG CGAGGGCGGT TTGGTTGCGG


 


401
TTTCGCTTTC GCAACGCTCG CCGGAAGCGT TTGTTAATGC CGAATATCTG


 


451
TATCGGAACG ATCGTCCGTT TTCTGTAAAT GTGTACGGCG GAACGGCTCA


 


501
CGGGGAAAAT TATGAAACGA CAGGAGAATA TCGGGTTGTT TGGCAACCGG


 


551
ACGGTTCGGT ATTTGATGCG GCGGGGCGCG GGAAAATCGG GGAAGATGTT


 


601
TATGAGCATT GCCTCGGGTG TTATCAGATG GCCCAGGTAT ATTTGGCGAA


 


651
ATACCGGGAT GTCGCGAATG ACGAGCAGAA GGTTTGGGAC TTCCGCGAAG


 


701
AGAGCAACCG GATTGCATCG GACTCGCGCG ATTATGTGTT TTATCAGAAT


 


751
ATGCGGGAAT TGATGCCCCG GGGGATGAAG GCGAACAGTC TTGTGGTCGG


 


801
CTATGATGCG GACGGTCTGC CGCAAAAAGT CTATTGGAGT TTCGACAATG


 


851
GAAAAAAACG CCAGAGTTTC GAATATTATT TGAAAAACGG AAATCTTTTT


 


901
ATTGCACAAT CTTCGACGGT AGCATTGAAA GCGGATGGCG TAACGGCGGA


 


951
TATGCAGACC TATCATGCGC AACAGACGTG GTATTTGGAT GGCGGGCGGA


 


1001
TTATCCGCGA AGAGAAACAG GGAGACAGAC TGCCTGATTT TCCTTTGAAC


 


1051
TTGGAAGATT TGGAAAAAGA GGTGAGCCGT TATGCAGAGG CTGCGGCGAG


 


1101
ACGTTCGGGC GGCAGGCGCG GCCTTTCTCA CTGA






This corresponds to the amino acid sequence <SEQ ID 2458; ORF 728>:










g728.pep




1
MFKKFKPVLL SFFALVFAFW LGTGIAYEIN PRWFLSDTAT EVPENPNAFV


 


51
AKLARLFRNA DRAVVIVKES MRTEESLAGA VDDGPLQSEK DYLALAIRLS


 


101
RLKEKAKWFH VTEQEHGEEV WLDYYIGEGG LVAVSLSQRS PEAFVNAEYL


 


151
YRNDRPFSVN VYGGTAHGEN YETTGEYRVV WQPDGSVFDA AGRGKIGEDV


 


201
YEHCLGCYQM AQVYLAKYRD VANDEQKVWD FREESNRIAS DSRDYVFYQN


 


251
MRELMPRGMK ANSLVVGYDA DGLPQKVYWS FDNGKKRQSF EYYLKNGNLF


 


301
IAQSSTVALK ADGVTADMQT YHAQQTWYLD GGRIIREEKQ GDRLPDFPLN


 


351
LEDLEKEVSR YAEAAARRSG GRRGLSH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2459>:










m728.seq




1
ATGTTTAAAA AATTCAAACC GGTACTGTTG TCATTTTTTG CACTTGTATT


 


51
TGCCTTTTGG CTGGGAACGG GTATTGCCTA TGAGATTAAT CCGCGTTGGT


 


101
TTTTGAGCGA TACGGCAACT GAAGTACCTA AAAATCCGAA TGCTTTTGTG


 


151
GCGAAACTTG CCCGCCTGTT CCGAAATGCC GACAGGGCGG TTGTCATCGT


 


201
GAAGGAATCG ATAAGGACGG AGGAAAATCT TGCCGGAACT GTGGATGACG


 


251
GTCCGTTGCA GTCGGAGAAG GATTATCTCG CGCTCGCTAT CCGGCTCAGT


 


301
CGTTTGAAAG AAAAGGCGAA ATGGTTTCAC GTAACGGAGC AGGAACATGG


 


351
GAAAGAGGTT TGGCTGGATT ACCATATCGG CGAGGGCGGT TTGGTTGCGG


 


401
TTTCGCTTTC GCAACGCTCG CCGGAAGCAT TTGTTAATGC CGAATATCTG


 


451
TATCGGAACG ATCGTCCGTT TTCTGTAAAT GTGTACGGCG GAACGGTTCA


 


501
CGGGGAAAAT TATGAAACGA CAGGAGAATA TCGGGTTGTT TGGCAACCAG


 


551
ACGGTTCGGT ATTTGATGCG GCGGGGCGCG GGAAAATCGG GGAAGATGTT


 


601
TATGAGCATT GCCTCGGGTG TTATCAGATG GCCCAGGTAT ATTTGGCGAA


 


651
ATACCGGGAT GTCGCGAATG ACGAGCAGAA GGTTTGGGAC TTCCGCAAAG


 


701
AGAGCAACCG AATTGCGTCG GACTCGCGCA ATTCTGTGTT TTATCAGAAT


 


751
ATGCGGGAAT TGATGCCCCG AGGGATGAAG GCGAACAGTC TTGTGGTCGG


 


801
CTATGATGCG GACGGTCTGC CGCAAAAAGT CTATTGGAGT TTCGACAATG


 


851
GAAAAAAACG CCAGAGTTTC GAATATTATT TGAAAAACGG AAATCTTTTT


 


901
ATTGCACAAT CTTCGACGGT AGCATTGAAA GCGGATGGCG TAACGGCGGA


 


951
TATGCAGACC TATCATGCGC AACAGACGTG GTATTTGGAT GGCGGGCGGA


 


1001
TTGTCCGCGA AGAGAAACAG GGAGACAGAC TGCCTGATTT TCCTTTGAAC


 


1051
TTGGAAAATT TGGAAAAAGA GGTGCGCCGT TATGCAGAGG CTGCGGCGAG


 


1101
ACGTTCGGGC GGCAGGCGCG ACCTTTCTCA CTGA






This corresponds to the amino acid sequence <SEQ ID 2460; ORF 728>:










m728.pep




1
MFKKFKPVLL SFFALVFAFW LGTGIAYEIN PRWFLSDTAT EVPKNPNAFV


 


51
AKLARLFRNA DRAVVIVKES IRTEENLAGT VDDGPLQSEK DYLALAIRLS


 


101
RLKEKAKWFH VTEQEHGKEV WLDYHIGEGG LVAVSLSQRS PEAFVNAEYL


 


151
YRNDRPFSVN VYGGTVHGEN YETTGEYRVV WQPDGSVFDA AGRGKIGEDV


 


201
YEHCLGCYQM AQVYLAKYRD VANDEQKVWD FRKESNRIAS DSRNSVFYQN


 


251
MRELMPRGMK ANSLVVGYDA DGLPQKVYWS FDNGKKRQSF EYYLKNGNLF


 


301
IAQSSTVALK ADGVTADMQT YHAQQTWYLD GGRIVREEKQ GDRLPDFPLN


 


351
LENLEKEVRR YAEAAARRSG GRRDLSH*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 728 shows 96.3% identity over a 377 aa overlap with a predicted ORF (ORF728.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2461>:










a728.seq




1
ATGTTTAAAA AATTCAAACC GGTACTGTTG TCATTTTTTG CACTTGTATT


 


51
TGCCTTTTGG CTGGGAACGG GTATTGCCTA TGAGATTAAT CCGCGTTGGT


 


101
TTTTGAGCGA TACGGCAACT GAAAATCCGA ATGCTTTTGT GGCGAAACTT


 


151
GCCCGCCTGT TCCGAAATGC CGACAGGGCG GTTGTCATCG TGAAGGAATC


 


201
GATGAGGACG GAGGAAAGTC TTGCCGGAGC TGTGGATGAC GGTCCGTTGC


 


251
AGTCGGAGAA GGATTATCTT GCACTCGCTG TCCGGCTCAG TCGTTTGAAA


 


301
GAAAAGGCGA AATGGTTTCA CGTAACGGAG CAGGAACATG GGGAAGAGGT


 


351
TTGGCTGGAT TACTATATCG GCGAGGGCGG TTTGGTTGCG GTTTCGCTTT


 


401
CGCAACGCTC GCCGGAAGCG TTTGTTAATG CCGAATATCT GTATCGGAAC


 


451
GATCGTCCGT TTTCTGTAAA TGTGTACGGC GGAACGGTTC ACGGGGAAAA


 


501
TTATGAAACG ACAGGAGAAT ATCGGGTTGT TTGGCAACCG GACGGTTCGG


 


551
TATTTGATGC GTCGGGGCGC GGGAAAATCG GGGAAGATGT TTATGAGCAT


 


601
TGCCTCGGGT GTTATCAGAT GGCCCAGGTA TATTTGGCGA AATATCGGGA


 


651
TGTCGCGAAT GATGAGCAGA AGGTTTGGGA CTTCCGCGAA GAGAGTAACC


 


701
GGATTGCGTC GGACTCGCGC GATTCTGTGT TTTATCAGAA TATGCGGGAA


 


751
TTGATGCCCC GAGGGATGAA GGCAAACAGT CTTGTGGTCG GCTATGATGC


 


801
GGACGGTCTG CCGCAGAAAG TCTATTGGAG TTTCGACAAT GGGAAAAAAC


 


851
GCCAGAGTTT CGAATATTAT TTGAAAAACG GAAATCTTTT TATTGCACAA


 


901
TCTTCGACGG TAGCATTGAA AGCGGATGGC GTAACGGCGG ATATGCAGAC


 


951
CTATCATGCG CAACAGACGT GGTATTTAGA TGGCGGGCGG ATTGTCCGCG


 


1001
AAGAGAAACA GGGGGACAGA CTGCCTGATT TTCCTTTGAA CTTGGAAGAT


 


1051
TTGGAAAAAG AGGTGAGCCG TTATGCAGAG GCTGCGGCGA GACGTTCGGG


 


1101
CGGCAGGCGC GACCTTTCTC ACTGA






This corresponds to the amino acid sequence <SEQ ID 2462; ORF 728.a>:










a728.pep




1
MFKKFKPVLL SFFALVFAFW LGTGIAYEIN PRWFLSDTAT ENPNAFVAKL


 


51
ARLFRNADRA VVIVKESMRT EESLAGAVDD GPLQSEKDYL ALAVRLSRLK


 


101
EKAKWFHVTE QEHGEEVWLD YYIGEGGLVA VSLSQRSPEA FVNAEYLYRN


 


151
DRPFSVNVYG GTVHGENYET TGEYRVVWQP DGSVFDASGR GKIGEDVYEH


 


201
CLGCYQMAQV YLAKYRDVAN DEQKVWDFRE ESNRIASDSR DSVFYQNMRE


 


251
LMPRGMKANS LVVGYDADGL PQKVYWSFDN GKKRQSFEYY LKNGNLFIAQ


 


301
SSTVALKADG VTADMQTYHA QQTWYLDGGR IVREEKQGDR LPDFPLNLED


 


351
LEKEVSRYAE AAARRSGGRR DLSH*






a728/m728 96.3% identity in 377 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2463>:










g729.seq




1
ATGAATACTA CATTGAAAAC TACCTTGACC TCTGTTGCAG CAGCCTTTGC


 


51
ATTGTCTGCC TGCACCATGA TTCCTCAATA CGAGCAGCCC AAAGTCGAAG


 


101
TTGCGGAAAC CTTCCAAAAC GACACATCGG TTTCTTCCAT CCGCGCGGTT


 


151
GATTTGGGTT GGCATGACTA TTTTGCCGAC CCGCGCCTGC AAAAGCTGAT


 


201
CGACATCGCA CTCGAGCGCA ATACCAGTTT GCGTACAGCC GTATTGAACA


 


251
GCGAAATCTA CCGCAAACAA TACATGATCG AGCGCAACAA CCTCCTGCCC


 


301
ACGCTTGCCG CCAATGCGAA CGGCTCGCGC CAAGGCAGCT TGAGCGGCgg


 


351
caaTGTCAGC AGCAGCTACA ATGTCGGACT GGGTGcGGca tCTTACGAAC


 


401
TCGATCTGTT CgGGCGCGTG CGCagcaacA GcgaagcAGC ACTGcaggGC


 


451
tATTTTGCCA GCGTTGCCAA CcgcGATGCG GCACATTTGa ttCtGATTGC


 


501
CACCGTTGCC AAAGCCTATT TCAAcgaGcG TTATGCCGAA AAAGcgatgT


 


551
CTTTGGCGCa gcGTGTCTTG AAAACGCGCG AGGAAACCTA CAAGCTGTCC


 


601
GAATTGCGGT ACAAGGCAGG CGTGATTTCC GCCGTCGCCC TGCGCCAGCA


 


651
GGAAGCCTTG ATTGAATCTG CCAAAGCCGA TTATGCCCAT GCCGCGCGCa


 


701
gcCGCGAACA GGCGCGCAAT GCCTTGGCAA CCTTGATTAA ccGTCCGATA


 


751
CCCGAagaCC TGCCCGCCGG TTTGCCGTTG GACAagcAGT TTTTTGTTGA


 


801
AAAACTGCCT GCCGGTTTGA GTTCCGAAGT ATTGCTCGAC CGTCCCGACA


 


851
TCCGCGCCGC CGAACACGCG CTCAAACAGG CAAACGCCAA TATCGGTGCG


 


901
gcgCGCGCCg ccTTTTTCCC GTCCATCCGC CTGACCGGAA GCGTCGGTAC


 


951
GGGTTCTGTC GAATTGGGCG GGCTGTTCAA AAGCGGCACG GGCGTTTGGG


 


1001
CGTTCGCTCC GTCTATTACC CTGCCGATTT TTACTTGGGG AACGAACAAG


 


1051
GCGAACCTTG ATGTGGCAAA ACTGCGCCAA CAGGCACAAA TTGTTGCCTA


 


1101
TGAATCCGCC GTCCAATCCG CCTTTCAAGA CGTGGCAAAC GCATTGGCGG


 


1151
CGCGCGAGCA GCTGGATAAA GCCTATGACG CTTTAAGCAA ACAAAGCCGC


 


1201
GCCTCTAAAG AAGCGTTGCG CTTGGTCGGA CTGCGTTACA AACACGGCGT


 


1251
ATCCGGCGCG CTCGATTTGC TCGATGCGGA ACGCATCAGC TATTCGGCGG


 


1301
AAGGTGCGGC TTTGTCGGCA CAACTGACCC GCGCCGAAAA CCTTGCCGAT


 


1351
TTGTACAAGG CGCTCgacGG CGGATTGAAA CGGGATACCC AAACCGGCAA


 


1401
ATAA






This corresponds to the amino acid sequence <SEQ ID 2464; ORF 729>:










g729.pep




1
MNTTLKTTLT SVAAAFALSA CTMIPQYEQP KVEVAETFQN DTSVSSIRAV


 


51
DLGWHDYFAD PRLQKLIDIA LERNTSLRTA VLNSEIYRKQ YMIERNNLLP


 


101
TLAANANGSR QGSLSGGNVS SSYNVGLGAA SYELDLFGRV RSNSEAALQG


 


151
YFASVANRDA AHLILIATVA KAYFNERYAE KAMSLAQRVL KTREETYKLS


 


201
ELRYKAGVIS AVALRQQEAL IESAKADYAH AARSREQARN ALATLINRPI


 


251
PEDLPAGLPL DKQFFVEKLP AGLSSEVLLD RPDIRAAEHA LKQANANIGA


 


301
ARAAFFPSIR LTGSVGTGSV ELGGLFKSGT GVWAFAPSIT LPIFTWGTNK


 


351
ANLDVAKLRQ QAQIVAYESA VQSAFQDVAN ALAAREQLDK AYDALSKQSR


 


401
ASKEALRLVG LRYKHGVSGA LDLLDAERIS YSAEGAALSA QLTRAENLAD


 


451
LYKALDGGLK RDTQTGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2465>:










m729.seq




1
ATGGATACTA CATTGAAAAC CACCTTGACT TCTGTTGCAG CAGCCTTTGC


 


51
ATTGTCTGCC TGCACCATGA TTCCCCAATA CGAGCAGCCC AAAGTCGAAG


 


101
TTGCCGAAAC GTTCAAAAAC GATACCGCCG ACAGCGGCAT CCGCGCCGTC


 


151
GATTTAGGTT GGCATGACTA TTTTGCCGAC CCGCGCCTGC AAAAGCTGAT


 


201
CGACATCGCA CTCGAGCGCA ATACCAGTTT GCGTACCGCC GTATTGAACA


 


251
GCGAAATCTA CCGCAAACAA TACATGATTG AGCGCAACAA CCTCCTGCCC


 


301
ACGCTTGCCG CCAATGCGAA CGACTCGCGC CAAGGCAGCT TGAGCGGCGG


 


351
CAATGTAAGC AGCAGCTACA AAGTCGGACT GGGTGCGGCA TCTTACGAAC


 


401
TCGATCTGTT CGGGCGTGTA CGCAGCAGCA GCGAGGCGGC ACTGCAAGGC


 


451
TATTTCGCCA GCACCGCCAA CCGCGATGCG GCACATTTGA GCCTGATTGC


 


501
CACCGTTGCC AAAGCCTATT TCAACGAACG TTACGCCGAA GAAGCGATGT


 


551
CTTTGGCGCA ACGTGTTTTG AAAACGCGCG AGGAAACCTA CAAGCTGTCC


 


601
GAATTACGTT ACAAGGCAGG CGTGATTTCC GCCGTCGCCC TACGTCAGCA


 


651
GGAAGCCCTG ATCGAATCTG CCAAAGCCGA TTATGCCCAT GCCGCGCGCA


 


701
GCCGCGAACA GGCGCGCAAT GCCTTGGCAA CCTTGATTAA CCAACCGATA


 


751
CCCGAAGACC TGCCTGCCGG TTTGCCGCTG GACAAGCAGT TTTTTGTTGA


 


801
AAAACTGCCG GCCGGTTTGA GTTCCGAAGT ATTGCTCGAC CGTCCCGATA


 


851
TCCGTGCTGC CGAACACGCG CTCAAACAGG CAAACGCCAA TATCGGTGCG


 


901
GCACGCGCCG CCTTTTTCCC ATCCATCCGC CTGACCGGAA CCGTCGGTAC


 


951
GGGTTCTGCC GAATTGGGTG GGTTGTTCAA AAGCGGCACG GGCGTTTGGT


 


1001
CGTTCGCGCC GTCTATTACC CTGCCGATTT TTACCTGGGG TACGAACAAG


 


1051
GCGAACCTTG ATGTAGCCAA GCTGCGCCAA CAGGTACAAA TCGTTGCCTA


 


1101
TGAATCCGCC GTCCAATCCG CATTTCAAGA CGTGGCAAAC GCATTGGCGG


 


1151
CGCGCGAGCA GCTGGATAAA GCCTATGACG CTTTAAGCAA ACAAAGCCGC


 


1201
GCCTCTAAAG AAGCGTTGCG CTTGGTCGGC CTGCGTTACA AGCACGGCGT


 


1251
ATCCGGCGCG CTCGACTTGC TCGATGCGGA ACGCAGCAGC TATGCGGCGG


 


1301
AGGGTGCGGC TTTGTCGGCA CAACTGACCC GCGCCGAAAA CCTTGCCGAT


 


1351
TTGTACAAGG CACTCGGCGG CGGATTGAAA CGGGATACCC AAACCGACAA


 


1401
ATAA






This corresponds to the amino acid sequence <SEQ ID 2466; ORF 729>:










m729.pep




1
MDTTLKTTLT SVAAAFALSA CTMIPQYEQP KVEVAETFKN DTADSGIRAV


 


51
DLGWHDYFAD PRLQKLIDIA LERNTSLRTA VLNSEIYRKQ YMIERNNLLP


 


101
TLAANANDSR QGSLSGGNVS SSYKVGLGAA SYELDLFGRV RSSSEAALQG


 


151
YFASTANRDA AHLSLIATVA KAYFNERYAE EAMSLAQRVL KTREETYKLS


 


201
ELRYKAGVIS AVALRQQEAL IESAKADYAH AARSREQARN ALATLINQPI


 


251
PEDLPAGLPL DKQFFVEKLP AGLSSEVLLD RPDIRAAEHA LKQANANIGA


 


301
ARAAFFPSIR LTGTVGTGSA ELGGLFKSGT GVWSFAPSIT LPIFTWGTNK


 


351
ANLDVAKLRQ QVQIVAYESA VQSAFQDVAN ALAAREQLDK AYDALSKQSR


 


401
ASKEALRLVG LRYKHGVSGA LDLLDAERSS YAAEGAALSA QLTRAENLAD


 


451
LYKALGGGLK RDTQTDK*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 729 shows 95.7% identity over a 467 aa overlap with a predicted ORF (ORF729.a) from N. gonorrhoeae: 

m729/g729 95.7% identity in 467 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2467>:










a729.seq




1
ATGGATACTA CATTGAAAAC CACCTTGACT TCTGTTGCAG CAGCCTTCGC


 


51
ATTATCCGCC TGCACCATGA TTCCCCAATA CGAGCAGCCC AAAGTCGAAG


 


101
TTGCCGAAAC GTTCAAAAAC GATACCGCCG ACAGCGGCAT CCGTGCGGTC


 


151
GATTTGGGTT GGCATGACTA TTTTGCCGAC CCGCGCCTGC AAAAGCTGAT


 


201
CGACATCGCA CTCGAGCGCA ATACCAGTTT GCGTACCGCC GTATTGAACA


 


251
GCGAAATCTA CCGCAAACAA TACATGATTG AGCGCAACAA CCTCCTGCCC


 


301
ACGCTTGCCG CCAATGCGAA CGACTCGCGC CAAGGCAGCT TGAGCGGCGG


 


351
CAATGTAAGC AGCAGCTACA AAGTCGGACT GGGTGCGGCA TCTTACGAAC


 


401
TCGATCTGTT CGGGCGTGTA CGCAGCAGCA GCGAGGCGGC ACTGCAAGGC


 


451
TATTTCGCCA GCACCGCCAA CCGCGATGCG GCACATTTGA GCCTGATTGC


 


501
CACCGTTGCC AAAGCCTATT TCAACGAACG TTATGCCGAA GAAGCGATGT


 


551
CTTTGGCGCA ACGTGTTTTG AAAACGCGCG AGGAAACCTA CAAGCTGTCC


 


601
GAATTACGTT ACAAGGCAGG CGTGATTTCC GCCGTCGCCC TACGTCAGCA


 


651
GGAAGCCCTA ATCGAATCTG CCAAAGCCGA TTATGCCCAT GCCGCGCGCA


 


701
GCCGCGAACA GGCGCGCAAT GCCTTGGCAA CCCTGATTAA CCAACCGATA


 


751
CCCGACGACC TGCCCGCCGG TTTGCCGTTG GACAAGCAGT TTTTTGTTGA


 


801
GAAGCTGCCG GCCGGTTTGA GTTCCGAAGT ATTGCTCGAC CGTCCCGATA


 


851
TCCGTGCTGC CGAACACGCG CTCAAACAGG CAAACGCCAA TATCGGTGCG


 


901
GCACGCGCCG CCTTTTTCCC ATCCATCCGC CTGACCGGAA GCGTCGATAC


 


951
GCATTCTGCC GAATTGGGCG GGCTGTTCAA AAGCGGCACC GGCGTTTGGT


 


1001
TGTTCGCACC TTCCATTACC CTGCCGATTT TTACCTGGGG TACGAACAAG


 


1051
GCGAACCTCG ATGTAGCCAA GCTGCGCCAA CAGGCACAAA TCGTTGCCTA


 


1101
TGAAGCCGCC GTCCAATCCG CATTTCAAGA CGTGGCAAAC GCATTGACCG


 


1151
CGCGCGAGCA GTTGGATAAA GCCTATGACG CTTTAAGCAA ACAAAGCCGC


 


1201
GCCTCTAAAG AAGCGTTGCG TTTGGTCGGT CTGCGTTACA AACACGGCGT


 


1251
ATCCGGCGCG CTCGACTTGC TCGATGCGGA ACGCAGCAGC TATTCGGCGG


 


1301
AAGGTGCGGC TTTGTCGGCA CAACTGACCC GCGCCGAAAA CCTTGCCGAT


 


1351
TTGTACAAGG CACTCGGCGG CGGATTGAAA CGGGATACCC AAACCGACAA


 


1401
ATAA






This corresponds to the amino acid sequence <SEQ ID 2468; ORF 729.a>:










a729.pep




1
MDTTLKTTLT SVAAAFALSA CTMIPQYEQP KVEVAETFKN DTADSGIRAV


 


51
DLGWHDYFAD PRLQKLIDIA LERNTSLRTA VLNSEIYRKQ YMIERNNLLP


 


101
TLAANANDSR QGSLSGGNVS SSYKVGLGAA SYELDLFGRV RSSSEAALQG


 


151
YFASTANRDA AHLSLIATVA KAYFNERYAE EAMSLAQRVL KTREETYKLS


 


201
ELRYKAGVIS AVALRQQEAL IESAKADYAH AARSREQARN ALATLINQPI


 


251
PDDLPAGLPL DKQFFVEKLP AGLSSEVLLD RPDIRAAEHA LKQANANIGA


 


301
ARAAFFPSIR LTGSVDTHSA ELGGLFKSGT GVWLFAPSIT LPIFTWGTNK


 


351
ANLDVAKLRQ QAQIVAYEAA VQSAFQDVAN ALTAREQLDK AYDALSKQSR


 


401
ASKEALRLVG LRYKHGVSGA LDLLDAERSS YSAEGAALSA QLTRAENLAD


 


451
LYKALGGGLK RDTQTDK*






a729/m729 98.1% identity in 467 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2469>:










g730.seq




1
GTGAAACCGC TGCGCAGACT GACAAACCTC CTTGCCGCCT GCGCCGTAGC



 


51
GGCGGTCGCA CTCATACAGC CCGCCCTCGC GGCGGACTTG GCGCAAGACC


 


101
CGTTCATTAC CGATAACACC CAACGGCAGC ACTACGAACC CGGCGGCAAA


 


151
TACCACCTCT TCGGcgaCCC GCGCGGCAGC GTTTCCGACC GCACCGGCAA


 


201
AATCAACGTC ATCCAAGACT ATACCCACCA GATGGGCAAC CTGCTCATCC


 


251
AACAGGCGGC AATCCAAGGC AATCTTGGTT ACACCGTCCG CTTTTCCGGA


 


301
CACGGACACG AAGAACACGC CCCCTTCGAC AACCACGCCG CCGACAGCGC


 


351
AAGCGAAGAA AAAGGCAACG TTGACGACGG CTTTACCGTG TACCGGCTCA


 


401
ACTGGGAAGG ACACGAACAT CATCCCGCCG ATGCCTACGA CGGCCCGAAG


 


451
GGCGGCAATT ACCCCAAACC TACGGGCGCA CGAGACGAAT ACACCTATCA


 


501
CGTCAACGGC ACAGCCCGCA GTATCAAACT CAATCCGACC GACACCCGCA


 


551
GCATCCGGCA ACGCATATTC GACAACTACA ACAACCTCGG CAGCAATTTC


 


601
TCCGACCGCG CCGATGAAGC CAACAGAAAA ATGTTCGAGC ACAATGCCAA


 


651
GCTCGACCGC TGGGGCAACA GCATGGAGTT TGTCAACGGC GTCGCCGCCG


 


701
GCGCGCTCAA CCCCTTTATC AGCGCGGGCG AAGCCTTGGG CATAGGCGAC


 


751
ATACTGTACG GAACGCGCTA TGCCATAGAC AAAGCCGCGA TGCGCAACAT


 


801
CGCCCCCTTA CCCGCCGAGG GCAAATTCGC CGCCATCGGC GGCTTGGGCA


 


851
GCGCGGCGGG CTTTGAAAAA AATACGCGCG AAGCCGTTGA CCGGTGGATA


 


901
CAGGAAAACC CCAATGCCGC CGAAACCGTC GAAGCCCTGG TCAACGTCCT


 


951
GCCGTTTGCC AAAGTCAAAA ACCTGACAAA GGCGGCAAAA CCGGGGAAGG


 


1001
CTGCGGTTAG TGGGGATTTT TCTAAATCCT ACACCTGCTC CTTCCACGGC


 


1051
AGCACCTTGG TCAAAACGGC AGACGGCTAC AAAGCCATTG CCCATATTCA


 


1101
AGCCGGAGAC CGCGTCCTTT CCAAGGACGA GGCAAGCGGA GAAACGGGAT


 


1151
ACAAACCCGT TACCGCCCGA TACGGCAATC CGTATCAAGA AACCGTTTAC


 


1201
ATTGAAGTTT CAGACGGCAT CGGCAACAGC CAAACCCTGA TTTCCAACCG


 


1251
CATCCACCCG TTTTATTCGG ACGGCAAATG GATTAAGGCG GAAGATTTAA


 


1301
AAGCGGGAAG CCGGCTGTTA TCCGAAAGCG GCAAAACCCA AACCGTCCGC


 


1351
AACATCGTTG TCAAACCAAA ACCGCTCAAA GCCTACAATC TGACCGTTGC


 


1401
CGATTGGCAT ACCTACTTCG TCAAGGGTAA TCAGGCGGAA ACGGAAGGGG


 


1451
TTTGGGTTCA TAATGATTGT CCGCCTAAAC CAAAACCAAC CAATCATGCC


 


1501
CAACAAAGAA AAGAAGAAGC TAAAAACGAT TCTCATCGAA GTGTGGGAGA


 


1551
TTCCAATCGT GTCGTTCGCG AAGGAAAGCA ATATTTAGAT TCCGACACAG


 


1601
GAAACCATGT TTATGTAAAA GGAGATAAAG TGGTTATTCT AACTCCTGAT


 


1651
GGAAGACAGG TAACTCAATT TAAGAACTCG AAAGCCAATA CGTCAAAAAG


 


1701
GGTAAAAAAT GGGAAATGGA CACCAAAATA A






This corresponds to the amino acid sequence <SEQ ID 2470; ORF 730.ng>:










g730.pep




1
VKPLRRLTNL LAACAVAAVA LIQPALAADL AQDPFITDNT QRQHYEPGGK



 


51
YHLFGDPRGS VSDRTGKINV IQDYTHQMGN LLIQQAAIQG NLGYTVRFSG


 


101
HGHEEHAPFD NHAADSASEE KGNVDDGFTV YRLNWEGHEH HPADAYDGPK


 


151
GGNYPKPTGA RDEYTYHVNG TARSIKLNPT DTRSIRQRIF DNYNNLGSNF


 


201
SDRADEANRK MFEHNAKLDR WGNSMEFVNG VAAGALNPFI SAGEALGIGD


 


251
ILYGTRYAID KAAMRNIAPL PAEGKFAAIG GLGSAAGFEK NTREAVDRWI


 


301
QENPNAAETV EALVNVLPFA KVKNLTKAAK PGKAAVSGDF SKSYTCSFHG


 


351
STLVKTADGY KAIAHIQAGD RVLSKDEASG ETGYKPVTAR YGNPYQETVY


 


401
IEVSDGIGNS QTLISNRIHP FYSDGKWIKA EDLKAGSRLL SESGKTQTVR


 


451
NIVVKPKPLK AYNLTVADWH TYFVKGNQAE TEGVWVHNDC PPKPKPTNHA


 


501
QQRKEEAKND SHRSVGDSNR VVREGKQYLD SDTGNHVYVK GDKVVILTPD


 


551
GRQVTQFKNS KANTSKRVKN GKWTPK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2471>:










m730.seq




1
GTGAAACCGC TGCGCAGACT GACAAACCTC CTTGCCGCCT GCGCCGTAGC



 


51
GGCGGCCGCA CTCATACAGC CCGCCCTCGC GGCGGACTTG GCGCAAGACC


 


101
CGTTCATTAC CGATAACGCC CAACGGCAGC ACTACGAACC CGGCGGCAAA


 


151
TACCACCTCT TCGGCGACCC GCGCGGCAGC GTTTCCGACC GCACCGGCAA


 


201
AATCAACGTC ATCCAAGACT ATACCCACCA GATGGGCAAC CTGCTCATCC


 


251
AACAGGCAAA CATCAACGGC ACAATCGGCT ACCACACCCG CTTTTCCGGA


 


301
CACGGACACG AAGAACACGC CCCCTTCGAC AACCACGCCG CCGACAGCGC


 


351
GAGCGAAGAA AAAGGCAACG TTGACGAAGG CTTTACCGTA TACCGGCTCA


 


401
ACTGGGAAGG ACACGAACAT CATCCCGCCG ATGCCTACGA CGGCCCGAAG


 


451
GGCGGCAATT ACCCCAAACC TACGGGCGCA CGAGACGAAT ACACCTATCA


 


501
CGTCAACGGC ACAGCCCGCA GTATCAAACT CAATCCGACC GACACCCGCA


 


551
GCATCCGGCA ACGCATATCC GACAATTACA GCAACCTCGG CAGCAATTTC


 


601
TCCGACCGCG CCGATGAAGC CAACAGAAAA ATGTTCGAGC ACAATGCCAA


 


651
GCTCGACCGC TGGGGCAACA GCATGGAGTT TATCAACGGC GTCGCCGCCG


 


701
GCGCGCTCAA CCCCTTTATC AGCGCGGGCG AAGCCTTGGG CATAGGCGAC


 


751
ATACTGTACG GAACGCGCTA TGCCATAGAC AAAGCCGCAA TGCGCAACAT


 


801
CGCCCCCTTG CCCGCCGAGG GCAAATTCGC CGTCATCGGC GGCTTGGGCA


 


851
GCGTGGCGGG CTTTGAAAAG AATACGCGCG AAGCCGTTGA CCGGTGGATA


 


901
CAGGAAAATC CCAATGCCGC CGAAACCGTC GAAGCCGTCT TCAACGTTGC


 


951
CGCAGCAGCC AAAGTCGCGA AGTTGGCAAA GGCGGCAAAA CCAGGGAAGG


 


1001
CTGCGGTTAG CGGGGATTTT GCTGATTCTT ATAAAAAGAA ATTGGCTTTG


 


1051
TCTGATAGTG CGAGACAGTT ATATCAAAAT GCAAAGTATA GAGAAGCTCT


 


1101
AGATATACAT TATGAAGATT TAATTAGAAG AAAAACTGAT GGTTCATCAA


 


1151
AATTTATTAA CGGCAGAGAA ATTGACGCTG TTACGAATGA TGCTTTAATA


 


1201
CAAGCCAAAA GAACAATTTC AGCAATAGAT AAACCTAAAA ATTTCTTAAA


 


1251
TCAAAAAAAT AGAAAGCAAA TTAAAGCAAC CATCGAAGCA GCAAACCAAC


 


1301
AGGGAAAACG TGCAGAATTT TGGTTTAAAT ACGGTGTTCA TTCACAAGTT


 


1351
AAGTCATATA TTGAATCAAA AGGCGGCATT GTTAAAACAG GTTTAGGAGA


 


1401
TTAA






This corresponds to the amino acid sequence <SEQ ID 2472; ORF 730>:










m730.pep




1
VKPLRRLTNL LAACAVAAAA LIQPALAADL AQDPFITDNA QRQHYEPGGK



 


51
YHLFGDPRGS VSDRTGKINV IQDYTHQMGN LLIQQANING TIGYHTRFSG


 


101
HGHEEHAPFD NHAADSASEE KGNVDEGFTV YRLNWEGHEH HPADAYDGPK


 


151
GGNYPKPTGA RDEYTYHVNG TARSIKLNPT DTRSIRQRIS DNYSNLGSNF


 


201
SDRADEANRK MFEHNAKLDR WGNSMEFING VAAGALNPFI SAGEALGIGD


 


251
ILYGTRYAID KAAMRNIAPL PAEGKFAVIG GLGSVAGFEK NTREAVDRWI


 


301
QENPNAAETV EAVFNVAAAA KVAKLAKAAK PGKAAVSGDF ADSYKKKLAL


 


351
SDSARQLYQN AKYREALDIH YEDLIRRKTD GSSKFINGRE IDAVTNDALI


 


401
QAKRTISAID KPKNFLNQKN RKQIKATIEA ANQQGKRAEF WFKYGVHSQV


 


451
KSYIESKGGI VKTGLGD*






g730/m730 93.0% identity in 344 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2473>:










a730.seq




1
GTGAAACCGC TGCGAAGACT CATCAAGCTC CTTGCCGCCT GTGCCGTAGC



 


51
GGCGGCCGCA CTCATACAGC CCGCCCTCGC GGCGGACTTG GCGCAAGACC


 


101
CGTTCATTAC CGATAACGCC CAACGGCAGC ACTACGAACC CGGAGGCAAA


 


151
TACCACCTCT TCGGCGACCC GCGCGGCAGC GTCTCCGACC GCACCGGTCA


 


201
AATCAACGTC ATCCAAGACT ATACCCACCG GATGGGCAAC CTGCTCATCC


 


251
AGCAGGCAAA CATCAACGGC ACAATCGGCT ACCACACCCG CTTTTCCGGA


 


301
CACGGATACG AAGAACACGC CCCCTTCGAC AACCACGCCG CCGACAGCGC


 


351
GAGCGAAGAA AAAGGCAACG TTGACGAAGG CTTTACCGTA TACCGGCTCA


 


401
ACTGGGAAGG ACACGAACAT CATCCCGCCG ATGCCTACGA CGGCCCGAAG


 


451
GGCGGCAATT ACCCCAAACC TACGGGTGCA CGCGACGAAT ACACCTATCA


 


501
CGTCAACGGC ACAGCACGCA GCATCAAACT CAATCCGACC GACACCCGCA


 


551
GCATCCGGCA ACGCATATCC GACAATTACA GCAACCTCGG CAGCAATTTC


 


601
TCCGACCGCG CCGATGAAGC CAACAGAAAA ATGTTCGAGC ACAATGCCAA


 


651
GCTCGACCGC TGGGGCAACA GCATGGAGTT TATCAACGGC GTCGCCGCCG


 


701
GCGCGCTCAA CCCCTTTATC AGCGCGGGCG AAGCCTTGGG CATAGGCGAC


 


751
ATACTGTACG GAACGCGCTA TGCCATAGAC AAAGCCGCAA TGCGCAACAT


 


801
CGCCCCCTTG CCCGCCGAGG GCAAATTCGC CGTCATCGGC GGCTTGGGCA


 


851
GCGTGGCGGG CTTTGAAAAA AATACGCGCG AAGCCGTTGA CCGGTGGATA


 


901
CAGGAAAACC CCAATGCCGC CGAAACCGTC GAAGCCCTGG TCAACGTCCT


 


951
GCCGTTTGCC AAAGTCAAAA ACCTGACAAA GGCGGCAAAA CCGGGGAAGG


 


1001
CTGCGGTTAG CGGGGATTTT TCTGCTGCAT ACAATACAAG AACAACTAGA


 


1051
AAAGTTACTA CAGAAACAGA GGGGTTAAAT AGAATCAGAC AGAACCAGAA


 


1101
AAATAGTAAT ATACATGAGA AAAATTATGG AAGAGATAAT CCTAATCATA


 


1151
TTAATGTTTT ATCTGGAAAT TCTATACAAC ATATACTGTA TGGAGATGAA


 


1201
GCAGGAGGTG GGCATCTTTT TCCTGGCAAA CCTGGTAAGA CAACATTCCC


 


1251
CCAACATTGG TCAGCCAGTA AAATAACTCA TGAAATTAGT GATATCGTTA


 


1301
CATCCCCAAA AACGCAATGG TATGCACAGA CTGGAACAGG CGGCAAATAT


 


1351
ATTGCTAAAG GAAGACCAGC TAGGTGGGTA TCATATGAAA CGAGAGATGG


 


1401
AATTCGTATC AGAACAGTTT ATGAACCTGC AACAGGAAAA GTGGTAACTG


 


1451
CATTCCCCGA TAGAACCTCT AATCCCAAAT ATAACCCTGT AAAATAA






This corresponds to the amino acid sequence <SEQ ID 2474; ORF 730.a>:










a730.pep




1
VKPLRRLIKL LAACAVAAAA LIQPALAADL AQDPFITDNA QRQHYEPGGK



 


51
YHLFGDPRGS VSDRTGQINV IQDYTHRMGN LLIQQANING TIGYHTRFSG


 


101
HGYEEHAPFD NHAADSASEE KGNVDEGFTV YRLNWEGHEH HPADAYDGPK


 


151
GGNYPKPTGA RDEYTYHVNG TARSIKLNPT DTRSIRQRIS DNYSNLGSNF


 


201
SDRADEANRK MFEHNAKLDR WGNSMEFING VAAGALNPFI SAGEALGIGD


 


251
ILYGTRYAID KAAMRNIAPL PAEGKFAVIG GLGSVAGFEK NTREAVDRWI


 


301
QENPNAAETV EALVNVLPFA KVKNLTKAAK PGKAAVSGDF SAAYNTRTTR


 


351
KVTTETEGLN RIRQNQKNSN IHEKNYGRDN PNHINVLSGN SIQHILYGDE


 


401
AGGGHLFPGK PGKTTFPQHW SASKITHEIS DIVTSPKTQW YAQTGTGGKY


 


451
IAKGRPARWV SYETRDGIRI RTVYEPATGK VVTAFPDRTS NPKYNPVK*






a730/m730 88.6% identity in 376 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2475>:










g731.seq




1
gattttcgag cgttttcatG CGAGAACGGT TTGTCTGTGC GCGTCCGCAA



 


51
TTTGGACGGC GGCAAAATCG CGTTGCGGCT GGACGGCAGG CGTGCCGTCC


 


101
TCTCTTCCGA CGTTGCCGCA TCCGGCGAAC GCTATACCGC CGAACACGGT


 


151
TTGTTCGGAA ACGGAACCGA GTGGCACCAG AAAGGCGGCG AAGCCTTTTT


 


201
CGGCTTTACC GATGCCTACG GCAATTCGGT CGAAACTTCC TGCCGCGCCC


 


251
GTTAA






This corresponds to the amino acid sequence <SEQ ID 2476; ORF 731.ng>:










g731.pep




1
DFRAFSCENG LSVRVRNLDG GKIALRLDGR RAVLSSDVAA SGERYTAEHG



 


51
LFGNGTEWHQ KGGEAFFGFT DAYGNSVETS CRAR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2477>:










m731.seq




1
ATGAATATCA GGTTTTTCGC GCTGACCGTA CCGGTTTTGT CTTTGGCGGC



 


51
CTGTGCCGTG CCGGAGGCGT ATGATGACGG CGGACGCGGG CATATGCCGC


 


101
CCGTTCAAAA CCAAGCCGGC ACGGACGATT TTCGGGCGTT TTCCTGCGAG


 


151
AACGGTTTGT CTGTGCGCGT CCGCCATTTG GACAGCGGCA AAGTCGCGTT


 


201
GCGGCTGGAC GGCAGGCGTG CCGTCCTCTC TTCCGACGTT GCCGCATCCG


 


251
GCGAACGCTA TACCGCCGAA CACGGTTTGT TCGGAAACGC AACCGAGTGG


 


301
CACCAGAAAG GCGGCGAAGC CTTTTTCGGC TTTACCGATG CCTACGGCAA


 


351
TTCGGTCGAA ACTTCCTGCC GCGCCCGTTA A






This corresponds to the amino acid sequence <SEQ ID 247R; ORF 731>:










m731.pep




1
MNIRFFALTV PVLSLAACAV PEAYDDGGRG HMPPVQNQAG TDDFRAFSCE



 


51
NGLSVRVRHL DSGKVALRLD GRRAVLSSDV AASGERYTAE HGLFGNATEW


 


101
HQKGGEAFFG FTDAYGNSVE TSCRAR*






g731/m731 95.2% identity in 84 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2479>:










a731.seq




1
ATGAATATCA GGTTTTTCGC GCTGACCGTA CCGGTTTTGT CTTTGGCGGC



 


51
CTGTGCCGTG CCGGAGGCGT ATGATGACGG CGGACGAGGG CATATGCCGC


 


101
CCGTTCAAAA CCAAGCCGGC ACGGCAGATT TTCGGGCATT TTCCTGCGAG


 


151
AACGGTTTGT CTGTGCACGT CCGCCGTTTG GACGGCGGCA GAATCGCGTT


 


201
GCGGTTGGAC GGCAGGCGTG CCGTCCTCTC TTCCGACGTT GCCGCATCCG


 


251
GCGAACGCTA TACCGCCGAA CACGGTTTGT TCGGAAACGG AACCGAGTGG


 


301
CATCAGAAAG GCGGCGAAGC CTTTTTCGGC TTTACCGATG CCTACGGCAA


 


351
TTCGGTCGAA ACCTCCTGCC GCGAACGCTA A






This corresponds to the amino acid sequence <SEQ ID 2480; ORF 731.a>:










a731.pep




1
MNIRFFALTV PVLSLAACAV PEAYDDGGRG HMPPVQNQAG TADFRAFSCE



 


51
NGLSVHVRRL DGGRIALRLD GRRAVLSSDV AASGERYTAE HGLFGNGTEW


 


101
HQKGGEAFFG FTDAYGNSVE TSCRAR*






a731/m731 94.4% identity in 126 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2481>:










g732.seq




1
ATGTCGAAAC CTGTTTTTAA GAAAATCGCA CTTTATACTT TGGGTGCAAT



 


51
CAGCGGCGTG GCCGTAAGTC TGGCGGTGCA GGGTTTTGCC GCCGagaagg


 


101
ACGGgcgGGA TAACGAagtC CTGCCGGTGC AATCCATCCG TACGATGGCG


 


151
GAGGTTTACG GTCAGATTAA GGCAAACTAC TATCATGACA AACCCGATGC


 


201
CGATTTGTTT GAAGGTGCGA TGAAGGGTAT GGTGGCCGGT TTGGATCCGC


 


251
ATTCCGAATA TATGGATAAA AAAGGTTATG CCGAGATAAA GGAGTCCACC


 


301
AGCGGCGAAT TTGGCGGCTT GGGGATGGAA ATCGGGCAGG AAGACGGTTT


 


351
TGTCAAAGTG GTTTCGCCGA TTGAGGACAC GCCTGCCGAA CGGGCGGAGG


 


401
TGAAAAGCGG CGATTTCATT GTGAAAATCG ATAATGTTTC GACGCGCGGT


 


451
ATGACGGTCA GCGAAGCGGT GAAAAAAATG CGGGGCAAGC CGGGTACGAA


 


501
GATTACTTTG ACGTTGTCGC GCAAAAATGC CGACAAGCCG ATAGTCGTCA


 


551
ACCTGACCCG TGCCATTATT AAAGTGAAAA GCGTCCGCCA TCACCTGATC


 


601
GAACCCGATT ACGGCTATAT CCGCGTGTCG CAGTTCCAAG AGCGGACGGT


 


651
CGAAAGCGTC AATACCGCCG CAAAAGAGCT GGTAAAGGAA AATAAAGGAA


 


701
AACCGCTCAA GGGGCTGGTG TTGGATTTGC GCGACGACCC CGGCGGGCTT


 


751
TTGACCGGCG CGGTCGGCGT GTCGGCGGCG TTTCTGCCGT CTGAAGCGGT


 


801
CGTCGTCAGC ACCAAGGGAC GCGACGGCAA AGACGGCATG GTACTGAAAG


 


851
CCGTTCCCGA GGATTATGTG TACGGTATGG GCGGCGACCC TTTGGCGGGT


 


901
ATTCCTGCCG AGTTGAAAAC GATTCCGATG ACGgtaTTGG TcaaTTCCGG


 


951
TTCggcttCC GCGTCGGAGA TTGtcgCCGG CGCATTGCAG GACCACAAAC


 


1001
GCGCGGTCAT CGTCGGTACG CAGAGCTTCG GTAAAGGTTC GGTTCAGACT


 


1051
TTGATTCCTT TGTCCAACGG CAGCGCGGTC AAGTTGACGA CCGCCCTGTA


 


1101
TTACACGCCG AACGACCGTT CCATTCAGGC ACAGGGGATT GTTCCCGATG


 


1151
TCgaaGTAAA AGATAAGGAA CGTACTTTTG AAAGCCGCGA GGCGGACCTG


 


1201
GTCGGACACA TCGGCAATCC CTTgggcGGC GAGGATGTGA ACAGTGAAAC


 


1251
CCttgcCGTA CCGCTTGAAA AAGATGCGGA TAAGCCCGCT GCAAAAGAAA


 


1301
AAGGTAAAAA GAAAAAGGAC GAGGATTTGT CTTCAAGGCG GATTCCGAAC


 


1351
CCTGCGAAAG ACGATCAGTT GCGTAAGGCT TTGGATTTGG TCAAGTCGCC


 


1401
CGAGCAGTGG CAGAAGTCTT TGGGGCTGGC GGCGAAAAAA CCGGTTTCAA


 


1451
ATAAAGATAA AAAAGATAAG AAGTAG






This corresponds to the amino acid sequence <SEQ ID 2482; ORF 732>:










g732.pep




1
MSKPVFKKIA LYTLGAISGV AVSLAVQGFA AEKDGRDNEV LPVQSIRTMA



 


51
EVYGQIKANY YHDKPDADLF EGAMKGMVAG LDPHSEYMDK KGYAEIKEST


 


101
SGEFGGLGME IGQEDGFVKV VSPIEDTPAE RAEVKSGDFI VKIDNVSTRG


 


151
MTVSEAVKKM RGKPGTKITL TLSRKNADKP IVVNLTRAII KVKSVRHHLI


 


201
EPDYGYIRVS QFQERTVESV NTAAKELVKE NKGKPLKGLV LDLRDDPGGL


 


251
LTGAVGVSAA FLPSEAVVVS TKGRDGKDGM VLKAVPEDYV YGMGGDPLAG


 


301
IPAELKTIPM TVLVNSGSAS ASEIVAGALQ DHKRAVIVGT QSFGKGSVQT


 


351
LIPLSNGSAV KLTTALYYTP NDRSIQAQGI VPDVEVKDKE RTFESREADL


 


401
VGHIGNPLGG EDVNSETLAV PLEKDADKPA AKEKGKKKKD EDLSSRRIPN


 


451
PAKDDQLRKA LDLVKSPEQW QKSLGLAAKK PVSNKDKKDK K*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2483>:










m732.seq




1
ATGTCGAAAC CTGTTTTTAA GAAAATCGCA CTTTATACTT TGGGTGCAAT



 


51
CAGCGGCGTG GCCGTCAGTC TGGCGGTGCA GGGTTTTGCC GCCGAGAAGG


 


101
ACAGGCGGGA TAACGAAGTC CTGCCGGTGC AATCCATCCG CACAATGGCG


 


151
GAGGTTTACG GTCAAATCAA GGCAAACTAC TATCAGGACA AACCCGATGC


 


201
CGATTTGTTT GAAGGTGCGA TGAAGGGTAT GGTGGCCGGT TTGGATCCGC


 


251
ATTCCGAATA TATGGATAAA AAAGGTTATG CCGAGATAAA GGAGTCCACC


 


301
AGCGGCGAAT TTGGCGGCTT GGGGATGGAA ATCGGGCAGG AAGACGGATT


 


351
TGTCAAAGTG GTTTCGCCGA TTGAGGACAC GCCTGCGGAA CGGGCGGGGG


 


401
TGAAAAGCGG CGATTTCATT GTGAAAATCG ATAATGTTTC GACACGCGGC


 


451
ATGACGGTCA GCGAAGCGGT GAAGAAAATG CGGGGCAAGC CGGGTACGAA


 


501
GATTACTTTG ACGCTGTCGC GCAAAAATGC CGACAAGCCG ATAGTCGTCA


 


551
ACCTGACCCG TGCCATTATT AAAGTGAAAA GCGTCCGCCA TCACCTGATC


 


601
GAACCCGATT ACGGCTATAT CCGCGTGTCG CAGTTCCAAG AGCGGACGGT


 


651
CGAAAGCGTC AATACCGCCG CAAAAGAGCT GGTAAAGGAA AATAAAGGAA


 


701
AACCGCTCAA GGGGCTGGTG TTGGATTTGC GCGACGACCC CGGCGGGCTT


 


751
TTGACTGGCG CGGTCGGCGT GTCGGCGGCA TTTCTGCCGT CTGAAGCAGT


 


801
CGTCGTCAGC ACCAAGGGAC GCGACGGCAA AGACCGCATG GTACTGAAAG


 


851
CCATTCCTGA AGATTATGTG TACGGGATGG GCGGCGATTC GTTGGCGGGC


 


901
ATTCCTGCCG AGTTGAAAAC CATACCGATG ACGGTATTGG TCAATTCCGG


 


951
TTCGGCTTCC GCGTCGGAGA TTGTCGCAGG TGCATTGCAG GATCATAAAC


 


1001
GCGCGGTCAT CGTCGGTACG CAGAGCTTCG GCAAAGGTTC GGTTCAGACT


 


1051
TTGATTCCTT TGTCCAACGG CAGCGCGGTC AAGCTGACAA CGGCACTGTA


 


1101
TTATACGCCG AACGACCGTT CTATTCAGGC GCAGGGGATT GTTCCCGATG


 


1151
TCGAAGTAAA AGATAAGGAA CGCATTTTTG AAAGCCGCGA GGCGGATTTG


 


1201
GTCGGACACA TCGGCAATCC CTTGGGCGGC GAGGATGTGA ACGGTGAAAC


 


1251
CCTTGCCGTG CCGCTTGAAA AAGATGCGGA TAAGCCCGCT GTAAAAGAAA


 


1301
AAGGTAAAAA GAAAAAGGAC GAGGATTTGT CTTCAAGGCG GATTCCCAAC


 


1351
CCTGCCAAAG ACGACCAGTT GCGGAAAGCT TTGGATTTAG TCAAGTCGCC


 


1401
CGAGCAGTGG CAGAAGTCTT TGGGGCTGGC GGCGAAAAAG CCGGTTTCAA


 


1451
ATAAAGATAA GAAAGATAAA AAAGATAAGA AGTAG






This corresponds to the amino acid sequence <SEQ ID 2484; ORF 732>:










m732.pep




1
MSKPVFKKIA LYTLGAISGV AVSLAVQGFA AEKDRRDNEV LPVQSIRTMA


 


51
EVYGQIKANY YQDKPDADLF EGAMKGMVAG LDPHSEYMDK KGYAEIKEST


 


101
SGEFGGLGME IGQEDGFVKV VSPIEDTPAE RAGVKSGDFI VKIDNVSTRG


 


151
MTVSEAVKKM RGKPGTKITL TLSRKNADKP IVVNLTRAII KVKSVRHHLI


 


201
EPDYGYIRVS QFQERTVESV NTAAKELVKE NKGKPLKGLV LDLRDDPGGL


 


251
LTGAVGVSAA FLPSEAVVVS TKGRDGKDRM VLKAIPEDYV YGMGGDSLAG


 


301
IPAELKTIPM TVLVNSGSAS ASEIVAGALQ DHKRAVIVGT QSFGKGSVQT


 


351
LIPLSNGSAV KLTTALYYTP NDRSIQAQGI VPDVEVKDKE RIFESREADL


 


401
VGHIGNPLGG EDVNGETLAV PLEKDADKPA VKEKGKKKKD EDLSSRRIPN


 


451
PAKDDQLRKA LDLVKSPEQW QKSLGLAAKK PVSNKDKKDK KDKK*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 732 shows 98.2% identity over a 491 as overlap with a predicted ORF (ORF732.a) from N. gonorrhoeae: 

m732/g732 98.2% identity in 491 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2485>:










a732.seq




1
ATGTCGAAAC CTGTTTTTAA GAAAATCGCA CTTTATACTT TGGGTGCAAT


 


51
CAGCGGCGTG GCCGTCAGTC TGGCGGTGCA GGGTTTTGCC GCCGAGAAGG


 


101
ACAGGCGGGA TAACGAAGTC CTGCCGGTGC AATCCATCCG CACAATGGCG


 


151
GAGGTTTACG GTCAAATCAA GGCAAACTAC TATCAGGACA AACCCGATGC


 


201
CGATTTGTTT GAAGGTGCGA TGAAGGGTAT GGTGGCCGGT TTGGATCCGC


 


251
ATTCCGAATA TATGGATAAA AAAGGTTATG CCGAGATAAA GGAGTCCACC


 


301
AGCGGCGAAT TTGGCGGCTT GGGGATGGAA ATCGGGCAGG AAGACGGATT


 


351
TGTCAAAGTG GTTTCGCCGA TTGAGGACAC GCCTGCGGAA CGGGCGGGGG


 


401
TGAAAAGCGG CGATTTCATT GTGAAAATCG ATAATGTTTC GACACGCGGC


 


451
ATGACGGTCA GCGAAGCGGT GAAGAAAATG CGGGGCAAGC CGGGTACGAA


 


501
GATTACTTTG ACGCTGTCGC GCAAAAATGC CGACAAGCCG ATAGTCGTCA


 


551
ACCTGACCCG TGCCATTATT AAAGTGAAAA GCGTCCGCCA TCACCTGATC


 


601
GAACCCGATT ACGGCTATAT CCGCGTGTCG CAGTTCCAAG AGCGGACGGT


 


651
CGAAAGCGTC AATACCGCCG CAAAAGAGCT GGTAAAGGAA AATAAAGGAA


 


701
AACCGCTCAA GGGGCTGGTG TTGGATTTGC GCGACGACCC CGGCGGGCTT


 


751
TTGACTGGCG CGGTCGGCGT GTCGGCGGCA TTTCTGCCGT CTGAAGCAGT


 


801
CGTCGTCAGC ACCAAGGGAC GCGACGGCAA AGACCGCATG GTACTGAAAG


 


851
CCGTTCCTGA AGATTATGTG TACGGGATGG GCGGCGATTC GTTGGCGGGC


 


901
ATTCCTGCCG AGTTGAAAAC CATACCGATG ACGGTATTGG TCAATTCCGG


 


951
TTCGGCTTCC GCGTCGGAGA TTGTCGCAGG TGCATTGCAG GATCATAAAC


 


1001
GCGCGGTCAT CGTCGGTACG CAGAGCTTCG GCAAAGGTTC GGTTCAGACT


 


1051
TTGATTCCTT TGTCCAACGG CAGCGCGGTC AAGCTGACAA CGGCACTGTA


 


1101
TTATACGCCG AACGACCGTT CTATTCAGGC GCAGGGGATT GTTCCCGATG


 


1151
TCGAAGTAAA AGATAAGGAA CGCATTTTTG AAAGCCGCGA GGCGGATTTG


 


1201
GTCGGACACA TCGGCAATCC TTTGGGCGGC GAGGATGTGA ACAGTGAAAC


 


1251
CCTTGCCGTG CCGCTTGAAA AAGATGCGGA TAAGCCCGCT GTAAAAGAAA


 


1301
AAGGTAAAAA GAAAAAGGAC GAGGATTTGT CTTCAAGGCG GATTCCCAAC


 


1351
CCTGCCAAAG ACGACCAGTT GCGGAAAGCT TTGGATTTAG TCAAGTCGCC


 


1401
CGAGCAGTGG CAGAAGTCTT TGGGGCTGGC GGCGAAAAAG CCGGTTTCAA


 


1451
ATAAAGATAA GAAAGATAAA AAAGATAAGA AGTAG






This corresponds to the amino acid sequence <SEQ ID 2486; ORF 732.a>:










a732.pep




1
MSKPVFKKIA LYTLGAISGV AVSLAVQGFA AEKDRRDNEV LPVQSIRTMA


 


51
EVYGQIKANY YQDKPDADLF EGAMKGMVAG LDPHSEYMDK KGYAEIKEST


 


101
SGEFGGLGME IGQEDGFVKV VSPIEDTPAE RAGVKSGDFI VKIDNVSTRG


 


151
MTVSEAVKKM RGKPGTKITL TLSRKNADKP IVVNLTRAII KVKSVRHHLI


 


201
EPDYGYIRVS QFQERTVESV NTAAKELVKE NKGKPLKGLV LDLRDDPGGL


 


251
LTGAVGVSAA FLPSEAVVVS TKGRDGKDRM VLKAVPEDYV YGMGGDSLAG


 


301
IPAELKTIPM TVLVNSGSAS ASEIVAGALQ DHKRAVIVGT QSFGKGSVQT


 


351
LIPLSNGSAV KLTTALYYTP NDRSIQAQGI VPDVEVKDKE RIFESREADL


 


401
VGHIGNPLGG EDVNSETLAV PLEKDADKPA VKEKGKKKKD EDLSSRRIPN


 


451
PAKDDQLRKA LDLVKSPEQW QKSLGLAAKK PVSNKDKKDK KDKK*






a732/m732 99.6% identity in 494 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2487>:










g733.seq




1
ATGATGAATC CGAAAACCTT GGGCCGTTTG TCGCTGTGTG CGGCGGTCTT


 


51
GGCTCTGACC GCCTGCGCCG GCGGCGGGCA TAAAAACCTG TATTATTACG


 


101
GCGGTTATCC CGATACCGTC TATGAAGGTT TGAAAAACGa cgACACTTCG


 


151
TTGGGCAAGC AGACCGAAAA GATGGAAAAA TACTTTGCGG AAGCCGCCAA


 


201
CAAAAAAATG AATGCCGCCC CGGGTGCGCA CGCCCATTTG GGACTGCTGC


 


251
TTTCCCGTTC GGGAGACAAA GAGGGCGCGT TCCGCCAATT TGAAGAAGAG


 


301
AAAAGGCTGT TTCCCGAATC GGGCGTATTT ATGGACTTCC TGATGAAAAC


 


351
CGGtaaAGGA GGCAAGCGAT GA






This corresponds to the amino acid sequence <SEQ ID 2488; ORF 733>:










g733.pep




1
MMNPKTLGRL SLCAAVLALT ACAGGGHKNL YYYGGYPDTV YEGLKNDDTS


 


51
LGKQTEKMEK YFAEAANKKM NAAPGAHAHL GLLLSRSGDK EGAFRQFEEE


 


101
KRLFPESGVF MDFLMKTGKG GKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2489>:










m733.seq




1
ATGATGAATC CGAAAACCTT GAGCCGTTTG TCGCTGTGTG CGGCGGTCTT


 


51
GGCTCTGACC GCCTGCGGCG GCAACGGGCA AAAATCCCTG TATTATTACG


 


101
GCGGCTATCC CGATACCGTC TATGAAGGTT TGAAAAACGA CGACACTTCG


 


151
TTGGGCAAGC AGACCGAAAA GATGGAAAAA TACTTTGTGG AAGCCGGCAA


 


201
CAAAAAAATG AATGCCGCCC CGGGTGCGCA CGCCCATCTG GGACTGCTGC


 


251
TTTCCCGTTC GGGAGACAAA GAGGGCGCGT TCCGCCAGTT TGAAGAAGAG


 


301
AAAAGGCTGT TTCCCGAATC GGGCGTATTT ATGGACTTCC TGATGAAAAC


 


351
CGGTAAAGGA GGCAAGCGAT GA






This corresponds to the amino acid sequence <SEQ ID 2490; ORF 733>:









m733.pep




1
MMNPKTLSRL SLCAAVLALT ACGGNGQKSL YYYGGYPDTV YEGLKNDDTS


 


51
LGKQTEKMEK YFVEAGNKKM NAAPGAHAHL GLLLSRSGDK EGAFRQFEEE


 


101
KRLFPESGVF MDFLMKTGKG GKR*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 733 shows 94.3% identity over a 123 aa overlap with a predicted ORF (ORF733.a) from N. gonorrhoeae: 

m733/g733





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2491>:










a733.seq




1
ATGATGAATC CGAAAACCTT GAGCCGTTTG TCGCTGTGTG CGGCGGTCTT


 


51
GGCTCTGACC GCCTGCGGCG GCAACGGGCA AAAATCCCTG TATTATTACG


 


101
GCGGCTATCC CGATACCGTC TATGAAGGTT TGAAAAACGA CGACACTTCG


 


151
TTGGGCAAGC AGACCGAAAA GATGGAAAAA TACTTTGTGG AAGCCGGCAA


 


201
CAAAAAAATG AATGCCGCCC CGGGTGCGCA CGCCCATCTG GGACTGCTGC


 


251
TTTCCCGTTC GGGAGACAAA GAGGGCGCGT TCCGCCAGTT TGAAGAAGAG


 


301
AAAAGGCTGT TTCCCGAATC GGGCGTATTT ATGGACTTCC TGATGAAAAC


 


351
CGGTAAAGGA GGCAAGCGAT GA






This corresponds to the amino acid sequence <SEQ ID 2492; ORF 733.a>:










a733.pep




1
MMNPKTLSRL SLCAAVLALT ACGGNGQKSL YYYGGYPDTV YEGLKNDDTS


 


51
LGKQTEKMEK YFVEAGNKKM NAAPGAHAHL GLLLSRSGDK EGAFRQFEEE


 


101
KRLFPESGVF MDFLMKTGKG GKR*






a733/m733 100.0% identity in 123 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2493>:










g734.seq




1
ATGATGAAAA AGATACTGGC AGTATCGGCA CTATGCCTGA TGACTGCGGC


 


51
GGCACAGGCT GCCGATACTT ACGGCTATCT CGCCGTTTGG CAGAATCCGC


 


101
AGGATGCAAA CGATGTTTTG CAGGTTAAAA CCACAAAAGA AGATTCGGCG


 


151
AAAAGCGAAG CGTTTGCCGA GTTGGAAGCC TTTTGCAAAG GTCAGGACAC


 


201
GCTTGCGGGC ATTGCCGAAG ACGAGCCGAC CGGATGCCGG TCGGTCGTGT


 


251
CGCTGAACAA TACCTGTGTC TCGCTGGCAT ACCCGAAAGC CTTGGGCGCG


 


301
ATGCGCGTTG AAAACGCCGT CGTGATTACT TCTCCGCGTT TTACGAGCGT


 


351
TCATCAGGTC GCACTCAACC AGTGCATAAA AAAATACGGC GCACAGGGAC


 


401
AATGCGGCTT GGAAACAGTG TATTGCACGT CATCTTCTTA TTACGGCGGG


 


451
GCTGTTCGCT CCTTAATCCA ACACCTGAAA TAA






This corresponds to the amino acid sequence <SEQ ID 2494; ORF 734.ng>:










g734.pep




1
MMKKILAVSA LCLMTAAAQA ADTYGYLAVW QNPQDANDVL QVKTTKEDSA


 


51
KSEAFAELEA FCKGQDTLAG IAEDEPTGCR SVVSLNNTCV SLAYPKALGA


 


101
MRVENAVVIT SPRFTSVHQV ALNQCIKKYG AQGQCGLETV YCTSSSYYGG


 


151
AVRSLIQHLK *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2495>:









m734.seq (partial)










1
TCGGGCATTG CTGAAGACGA GCCGACCGGA TGCCGGTCGG TCGTGTCGCT



 


51
GAACAATACC TGTGTCGCGC TGGCATACCC GAAAGCCTTG GGCGCGCTGC


 


101
GTGTCGACAA CGCCGTCGTG ATTACTTCTC CGCGTTTTAC GAGCGTTCAT


 


151
CAGGTCGCAC TCAACCAGTG CATCAAAAAA TACGGCGTAC AGGGACAATG


 


201
CGGCTTGGAA ACAGTGTATT GCACATCTTC TTCTTATTAC GGCGGAACTG


 


251
TGCGCTCTTT GATTCAAAAT CTCAAATAA






This corresponds to the amino acid sequence <SEQ ID 2496; ORF 734>:









m734.pep (partial)










1
SGIAEDEPTG CRSVVSLNNT CVALAYPKAL GALRVDNAVV ITSPRFTSVH



 


51
QVALNQCIKK YGVQGQCGLE TVYCTSSSYY GGTVRSLIQN LK*






m734/g734 92.4% identity in 92 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2497>:










a734.seq




1
ATGATGAAAA AGATACTGGC CGTATCGGCA CTATGCCTGA TGACTGCGGC


 


51
GGCACGGGCT GCCGATACTT ACGGCTATCT CGCCGTTTGG CAGAATCCGC


 


101
AGAATGCAAA CGATGTTTTG CAGGTTAAAA CCACAAAAGA AGATTCGACG


 


151
AAAAGCGAAG CGTTTGCCGA GTTGGAAGCT TTCTGCAAAG GTCAGGACAC


 


201
GCTTGCGGGC ATTGCCGAAG ACGAGCCGAC CGGATGCCGG TCGGTCGTGT


 


251
CGCTGAACAA TACCTGTGTC GCGCTGGCAT ACCCGAAAGC CTTGGGCGCG


 


301
ATGCGCGTTG AAAACGCCGT TGTGATTACT TCTCCGCGTT TTACGAGCGT


 


351
TTATCAGGTC GCACTCAACC AGTGCATCAA AAAATACGGC GCACAGGGAC


 


401
AATGCGGCTT GGAAACAGTG TATTGCACGT CTTCTTCTTA TTACGGGGGA


 


451
ACTGTGCGCT CTTTGATTCA AAATCTCAAA TAA






This corresponds to the amino acid sequence <SEQ ID 2498; ORF 734.a>:










a734.pep




1
MMKKILAVSA LCLMTAAARA ADTYGYLAVW QNPQNANDVL QVKTTKEDST


 


51
KSEAFAELEA FCKGQDTLAG IAEDEPTGCR SVVSLNNTCV ALAYPKALGA


 


101
MRVENAVVIT SPRFTSVYQV ALNQCIKKYG AQGQCGLETV YCTSSSYYGG


 


151
TVRSLIQNLK *






a734/g734 95.6% identity in 160 aa overlap





g735.seq not found yet

g735.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2499>:










m735.seq




1
ATGAATCTCG TGAAACTGCT GGCGAATAAC TGGCAACCGA TTGCCATTAT


 


51
CGCGCTTGTC GGCACGGGCT TGGCTGTGTC GCACCATCAA GGCTACAAGT


 


101
CGGCATTTGC GAAGCAGCAG GCGGTCATCG ACAAGATGGA GCGCGACAAG


 


151
GCGCAAGCCC TGCTGTTGTC GGCTCAAAAC TATGCGCGCG AACTGGAACT


 


201
GGCACGCGCG GAAGCTAAAA AATATGAAGT CAAGGCGCAC GCTGTCGGCA


 


251
TGGCTTTGGC GAAAAAACAG GCGGAAGTCA GCCGTCTGAA AACGGAAAAT


 


301
AAAAAGGAAA TCGAAAATGT CCTTACTCAA GACCGTAAAA ATGCAAGCGG


 


351
CGGTTGCATT GACGGCTTTG GCTCTCACGG CCTGCAGCTC TACAACCGCG


 


401
CCCTCGGCTA CGGAAATTAA






This corresponds to the amino acid sequence <SEQ ID 2500; ORF 735>:










m735.pep




1
MNLVKLLANN WQPIAIIALV GTGLAVSHHQ GYKSAFAKQQ AVIDKMERDK


 


51
AQALLLSAQN YARELELARA EAKKYEVKAH AVGMALAKKQ AEVSRLKTEN


 


101
KKEIENVLTQ DRKNASGGCI DGFGSHGLQL YNRALGYGN*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2501>:










a735.seq




1
ATGAATCTCG TGAAACTGCT GGCGAATAAC TGGCAACCGA TTGCCATCAT


 


51
CGCGCTTGTC GGCACGGGTT TGGCGGTGTC GCACCATCAA GGCTACAAGT


 


101
CGGCTTTTGC GAAGCAGCAG GCGGTCATTG AGAAAATGAA GCGCGACAAG


 


151
GCGCAAGCCC TGCTGTTGTC GGCTCAAAAC TACGCCCGCG AACTGGAACA


 


201
GGCGCGTGCG GAAGCTAAAA AATATGAAGT CAAGGCGCAC GCCGTCGGCA


 


251
TGGCTTTGGC GAAAAAACAG GCGGAAGTCA GCCGTCTGAA AACGGAAAAT


 


301
AAAAAGGAAA TCGAAAATGT CCTTACTCAA GACCGTAAAA ATGCAGGCGG


 


351
CGGTTGTATT GACGGCTTTG GCCATCACGG CTTGCAGCTC TACAAGCGCG


 


401
CCCTCGGCTA CGGAAATTAA






This corresponds to the amino acid sequence <SEQ ID 2502; ORF 735.a>:










a735.pep




1
MNLVKLLANN WQPIAIIALV GTGLAVSHHQ GYKSAFAKQQ AVIEKMKRDK


 


51
AQALLLSAQN YARELEQARA EAKKYEVKAH AVGMALAKKQ AEVSRLKTEN


 


101
KKEIENVLTQ DRKNAGGGCI DGFGHHGLQL YKRALGYGN*






a735/m735 95.7% identity in 139 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2503>:










g736.seq




1
ATGAATTTTA TCCGTTCCGT CGGGGCGAAA ACCCTCGGCC TTATTCAATC


 


51
CTTCGGCAGT ATCACGCTGT TTCTGCTGAA CATTTTGGCG AAATCCGGCA


 


101
CGGCTTTCGC CCGTCCGCGC CTGAGCGTGC GCCAAGTGTA TTTTGCCGGC


 


151
GTGCTGTCGG TGCTGATTGT TGCCGTTTCG GGGCTGTTCG TCGGTATGGT


 


201
TTTGGGTTTG CAGGGCTATA CGCAGTTGTC GAAATTCAAA TCCGCCGATA


 


251
TTTTGGGCTA TATGGTCGCG GCTTCTCTGT TGCGCGAACT GGGTCCCGTG


 


301
TTGGCGGCGA TTCTGTTTGC CAGCAGCGCG GGCGGTGCGA TGACCAGCGA


 


351
AATCGGTTTG ATGAAAACGA CCGGACAGCT CGAAGCGATG AACGTGATGG


 


401
CGGTCAACCC CGTCGCCCGC GTGGTTGCCC CGCGTTTTTG GGCGGGCGTG


 


451
TTTTCTATGC CGCTTTTGGC TTCGATTTTC AACGTCGCGG GCATTTTCGG


 


501
CGCGTATTTG GTCGGCGTGA GCTGGCTGGG TTTGGACAGC GGTATTTTCT


 


551
GGCCGCAGAT GCAGAACAAC ATTACGATAC ATTACGATGT AATCAACGGT


 


601
TTGATCAAAT CCGCCGCGTT CGGCGTGGCG GTAACGCTGA TTGCCGTGCA


 


651
TCAGGGCTTC CACTGCATCC CGACTTCGGA AGGCATTTTG CGCGCCAGCA


 


701
CGCGCACGGT GGTTTCGTCC GCCCTGACGA TTTTGGCGGT CGATTTTATA


 


751
TTGACCGCGT GGATGTTTAC AGATTGA






This corresponds to the amino acid sequence <SEQ ID 2504; ORF 736>:










g736.pep




1
MNFIRSVGAK TLGLIQSFGS ITLFLLNILA KSGTAFARPR LSVRQVYFAG


 


51
VLSVLIVAVS GLFVGMVLGL QGYTQLSKFK SADILGYMVA ASLLRELGPV


 


101
LAAILFASSA GGAMTSEIGL MKTTGQLEAM NVMAVNPVAR VVAPRFWAGV


 


151
FSMPLLASIF NVAGIFGAYL VGVSWLGLDS GIFWPQMQNN ITIHYDVING


 


201
LIKSAAFGVA VTLIAVHQGF HCIPTSEGIL RASTRTVVSS ALTILAVDFI


 


251
LTAWMFTD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2505>:










m736.seq




1
ATGAATTTTA TCCGTTCCGT CGGGGCGAAA ACCCTCGGCC TTATTCAATC


 


51
CTTCGGCAGT ATCACGCTGT TTCTGCTGAA CATTTTGGCG AAATCCGGCA


 


101
CGGCTTTCGC CCGTCCGCGC CTGAGCGTGC GCCAAGTGTA TTTTGCCGGC


 


151
GTGCTGTCGG TGCTGATTGT TGCCGTTTCG GGGCTGTTCG TCGGTATGGT


 


201
TTTGGGTTTG CAGGGCTATA CGCAGTTGTC GAAATTCAAA TCCGCCGATA


 


251
TTTTGGGCTA TATGGTCGCG GCTTCTCTGT TGCGCGAACT GGGTCCCGTG


 


301
TTGGCGGCGA TTCTGTTTGC CAGCAGCGCG GGCGGTGCGA TGACCAGCGA


 


351
AATCGGTTTG ATGAAAACGA CCGGACAGCT CGAAGCGATG AACGTGATGG


 


401
CGGTCAACCC CGTCGCCCGC GTGGTTGCCC CGCGTTTTTG GGCGGGCGTG


 


451
TTTTCTATGC CGCTTTTGGC TTCGATTTTC AACGTCGCGG GCATTTTCGG


 


501
CGCGTATTTG GTCGGCGTGA GCTGGCTGGG TTTGGACAGC GGTATTTTCT


 


551
GGCCGCAGAT GCAGAACAAC ATTACGATAC ATTACGATGT AATCAACGGT


 


601
TTGATCAAAT CCGCCGCGTT CGGCGTGGCG GTAACGCTGA TTGCCGTGCA


 


651
TCAGGGCTTC CACTGCATCC CGACTTCGGA AGGCATTTTG CGCGCCAGCA


 


701
CGCGCACGGT GGTTTCGTCC GCCCTGACGA TTTTGGCGGT CGATTTTATA


 


751
TTGACCGCGT GGATGTTTAC AGATTGA






This corresponds to the amino acid sequence <SEQ ID 2506; ORF 736>:










m736.pep




1
MNFIRSVGAK TLGLIQSLGS ITLFLLNILA KSGTAFVRPR LSVRQVYFAG


 


51
VLSVLIVAVS GLFVGMVLGL QGYTQLSKFK SADILGYMVA ASLLRELGPV


 


101
LAAILFASSA GGAMTSEIGL MKTTEQLEAM NVMAVNPVAR VVAPRFWAGV


 


151
FSMPLLASIF NVAGIFGAYL VGVTWLGLDS GIFWSQMQNN ITIHYDVING


 


201
LIKSAAFGVA VTLIAVHQGF HCVPTSEGIL RASTRTVVSS ALTILAVDFI


 


251
LTAWMFTD*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 736 shows 97.7% identity over a 258 aa overlap with a predicted ORF (ORF736.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2507>:










a736.seq




1
ATGAATTTTA TCCGTTCCGT CGGGGCGAAA ACCCTCGGCC TTATTCAATC


 


51
TCTCGGCAGT ATCACGCTGT TTCTGCTGAA TATTCTGGCG AAATCCGGTA


 


101
CGGCTTTCGT CCGTCCGCGC CTGAGCGTGC GCCAAGTGTA TTTTGCCGGC


 


151
GTGCTGTCGG TGTTGATTGT TGCCGTTTCA GGGCTGTTTG TCGGCATGGT


 


201
CTTGGGTTTG CAGGGCTATA CGCAGTTGTC GAAATTCAAA TCCGCCGATA


 


251
TTTTGGGCTA TATGGTCGCG GCTTCGCTGT TGCGCGAACT GGGTCCGGTG


 


301
TTGGCGGCGA TTCTGTTTGC CAGCAGCGCG GGCGGTGCGA TGACCAGCGA


 


351
AATCGGTTTG ATGAAAACGA CCGAACAGCT CGAAGCGATG AACGTGATGG


 


401
CGGTAAACCC CGTCGCCCGA GTGGTTGCGC CGCGCTTTTG GGCGGGCGTG


 


451
TTTTCCATGC CGCTTTTGGC TTCGATTTTC AACGTGGCGG GTATTTTCGG


 


501
CGCGTATTTG GTCGGTGTAA CCTGGCTGGG CTTGGACAGC GGTATTTTCT


 


551
GGTCGCAAAT GCAGAACAAC ATCACGATAC ATTACGATGT AATCAACGGT


 


601
CTGATCAAAT CCGCCGCGTT CGGCGTGGCG GTAACGCTGA TTGCCGTGCA


 


651
TCAGGGCTTC CACTGCGTCC CGACCTCGGA AGGCATTTTG CGCGCCAGCA


 


701
CGCGCACGGT GGTTTCGTCC GCCCTGACGA TTTTGGCGGT CGATTTTATA


 


751
TTGACCGCGT GGATGTTTAC AGATTGA






This corresponds to the amino acid sequence <SEQ ID 2508; ORF 736.a>:










a736.pep




1
MNFIRSVGAK TLGLIQSLGS ITLFLLNILA KSGTAFVRPR LSVRQVYFAG


 


51
VLSVLIVAVS GLFVGMVLGL QGYTQLSKFK SADILGYMVA ASLLRELGPV


 


101
LAAILFASSA GGAMTSEIGL MKTTEQLEAM NVMAVNPVAR VVAPRFWAGV


 


151
FSMPLLASIF NVAGIFGAYL VGVTWLGLDS GIFWSQMQNN ITIHYDVING


 


201
LIKSAAFGVA VTLIAVHQGF HCVPTSEGIL RASTRTVVSS ALTILAVDFI


 


251
LTAWMFTD*






a736/m736 100.0% identity in 258 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2509>:










g737.seq




1
atgaACATCA AACACCTTCT CTTGACCGCC GCCGCAACCG CACTGTTGGG


 


51
CATTTCCGCC CCCGCACTCG CCCACCACGA CGGACACGGC GATGACGACC


 


101
ACGGACACGC CGCACACCAA CACGGCAAAC AAGACAAAAT CATCAGCCGC


 


151
GCCCAAGCCG AAAAAGCGGC TTGGGCGCGT GTCGGCGGCA AAATCACCGA


 


201
CATCGATCTC GAACACGACG ACGGCCGTCC GCACTATGAT GTCGAAATCG


 


251
TCAAAAACGG ACAGGAATAC AAAGTCGTTG TCGATGCCCG TACCGGCCGC


 


301
GTGATTTCCT CCCGCCGCGA CGACTGA






This corresponds to the amino acid sequence <SEQ ID 2510; ORF 737>:










g737.pep




1
MNIKHLLLTA AATALLGISA PALAHHDGHG DDDHGHAAHQ HGKQDKIISR


 


51
AQAEKAAWAR VGGKITDIDL EHDDGRPHYD VEIVKNGQEY KVVVDARTGR


 


101
VISSRRDD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2511>:










m737.seq..




1
ATGAACATCA AACACCTTCT CTTGACCTCC GCCGCAACCG CACTGCTGAG


 


51
CATTTCCGCC CCCGCGCTCG CCCACCACGA CGGACACGGC GATGACGACC


 


101
ACGGACACGC CGCACACCAA CACAACAAAC AAGACAAAAT CATCAGCCGC


 


151
GCCCAAGCCG AAAAAGCAGC GTTGGCGCGT GTCGGCGGCA AAATCACCGA


 


201
CATCGATCTC GAACACGACA ACGGCCGTCC GCACTATGAT GTCGAAATCG


 


251
TCAAAAACGG ACAGGAATAC AAAGTCGTTG TCGATGCCCG TACCGGCCGC


 


301
GTGATTTCCT CCCGCCGCGA CGACTGA






This corresponds to the amino acid sequence <SEQ ID 2512; ORF 737>:










m737.pep




1
MNIKHLLLTS AATALLSISA PALAHHDGHG DDDHGHAAHQ HNKQDKIISR


 


51
AQAEKAALAR VGGKITDIDL EHDNGRPHYD VEIVKNGQEY KVVVDARTGR


 


101
VISSRRDD*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 737 shows 95.4% identity over a 108 aa overlap with a predicted ORF (ORF737.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2513>:










a737.seq




1
ATGAACTTCA AACGCCTTCT CTTGACCGCC GCCGCAACCG CACTGATGGG


 


51
CATTTCCGCC CCCGCACTCG CCCACCACGA CGGACACGGC GATGACGACC


 


101
ACGGACACGC CGCACACCAA CACAGCAAAC AAGACAAAAT CATCAGCCGC


 


151
GCCCAAGCCG AAAAAGCAGC GTTGGCGCGT GTCGGCGGCA AAATCACCGA


 


201
CATCGATCTC GAACACGACA ACGGCCGTCC GCACTATGAT GTCGAAATCG


 


251
TCAAAAACGG ACAGGAATAC AAAGTCGTTG TCGATGCCCG TACCGGCCGC


 


301
GTGATTTCCT CCCGCCGCGA CGACTGA






This corresponds to the amino acid sequence <SEQ ID 2514; ORF 737.a>:










a737.pep




1
MNFKRLLLTA AATALMGISA PALAHHDGHG DDDHGHAAHQ HSKQDKIISR


 


51
AQAEKAALAR VGGKITDIDL EHDNGRPHYD VEIVKNGQEY KVVVDARTGR


 


101
VISSRRDD*






a737/m737 94.4% identity in 108 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2515>:










g738.seq




1
ATGTCCGCTG AAACGACCGT ATCCGGCGCG CGCCCCGCCG CCAAACTGCC


 


51
GATTTACATC CTGCCCTGCT TCCTTTGGAT AGGCATCATC CCCTTTACCT


 


101
TCGCACTCAG GCTGAAACCG TCGCCCGACT TTTACCACGA TGCCGCCGCC


 


151
GCGGCCGGCC TGATTGTCCT GTTGTTCCTC ACGGCAGGAA AAAAGCTGTT


 


201
TGATGTCAAA ATCCCCGCCA TCAGCTTCCT CCTGTTTGCA ATGGCGGCAT


 


251
TTTGGTGGCT TCAGGCACGC CTGATGAACC TGATTTATCC CGGAATGAAC


 


301
GACATCGCCT CTTGGGTTTT CATCTTGCTC GCCGTCAGCG CGTGGGCCTG


 


351
CAAGAGTTTG GTCGCACACT ACGGACAAGA ACGCAtcgtT ACCCTGTTTG


 


401
CCTGGTCGCT GCTTATCGGC TCCCTGCTTC AATCCTGCAT CGTcgtCATC


 


451
CAGTTTGCCG GCTGGGAAAA CACCCCCCTG CTTCAAAACA TCATCGTTCA


 


501
CAGAGGGCAA GGCGTAATCG GACACATCGG GCAGCGCAAC AACCTCGGAC


 


551
ACTACCTCAT GTGGGGCATA CTCGCCTCCG CCTACCTCAA CGGACAACGA


 


601
AAAATCCCCG CAGCCCTCGG CGCAATCTGC CTGATTATGC AGACCGCCGT


 


651
TTTAGGTTTG GTCAATTCGC GCACCATCTT GACCTACATA GCCGCCATCG


 


701
CCCTCATCCT TCCCTTCTGG TATTTCCGTT CGGACAAATC CAACAGACGG


 


751
ACGATGCTCG GCATAGCCGC AGCCGTATTC CTTACCGCGC TGTTCCAATT


 


801
TTCCATGAAC GCCATTCTGG AAACCTTTAC AGGCATCCGC TACGAAACTG


 


851
CCGTCGAACG CGTCGCCAAC GGCGGTTTCA CAGACTTGCC GCGCCAAAGC


 


901
GAATGGAATA AAGCCCTTGC CGCCTTCCAG TCCGCCCCGA TATTCGGGCA


 


951
CGGCTGGAAC AGTTTTGCCC AACAAACCTT CCTGATCAAT GCCGAACAGC


 


1001
ACACCATACA CGACAACTTC CTCAGCACCT TGTTCACCCA TTCCCACAAC


 


1051
ATCATCCTCC AACTCCTTGC AGAAATGGGG ATCAGCGGCA CGCTTCTGGT


 


1101
TGCCGCAACC CTGCTGACGG GCATTGCCGG GCTGCTGAAA CGCTCCCTGA


 


1151
CCCCCGCATC ACTTTTCCTG CTGTGCGCGC TTGCCGTCAG TATGTGCCAC


 


1201
AGTATGCTCG AATATCCTTT GTGGTATGTC TATTTCCTCA TCCCCTTCGG


 


1251
ACTGATGCTC TTTCTGTCCC CCGCAGAGGC TTCAGACGGC ATCGCCTTCA


 


1301
AAAAAGCCGC CAATCTCGGC ATACTGACCG CCTCCGCCGC CATATTCGCA


 


1351
GGATTGCTGC ACTTGGACTG GACATACACC CGGCTGGTTA ACTCCTTTTC


 


1401
CCCCGCCGCT GACGACAGTG CCAAAACCCT CAACCGGAAA ATCAACGAAC


 


1451
TGCGCTATAT TTCCGCAAAC AGCCCGATGC TGTCCTTTTA TGCCGACTTC


 


1501
TCCCTCGTAA ACTTCGCCCT GCCGGAATAC CCCGAAACCC AGACTTGGGC


 


1551
GGAAGAAGCA ACCCTCAAAG CACTAAAATA CCGCCCCTAC TCCGCCACCT


 


1601
ACCGCATCGC CCTCTACTTG ATGCGGCAAG GCAAAGTTGC AGAAGCAAAA


 


1651
CAATGGATGC GGGCAACACA GTCCTATTAC CCCTACCTGA TGCCCCGATA


 


1701
CGCCGACGAA ATCCGCAAAC TGCCCGTATG GGCACCGCTG CTGCCCGAAC


 


1751
TGCTCAAAGA CTGCAAAGCC TTCGCCGCCG CTCCCGGCCA TCCGGAAACA


 


1801
AAACCCTGCA AATGA






This corresponds to the amino acid sequence <SEQ ID 2516; ORF 738>:










g738.pep




1
MSAETTVSGA RPAAKLPIYI LPCFLWIGII PFTFALRLKP SPDFYHDAAA


 


51
AAGLIVLLFL TAGKKLFDVK IPAISFLLFA MAAFWWLQAR LMNLIYPGMN


 


101
DIASWVFILL AVSAWACKSL VAHYGQERIV TLFAWSLLIG SLLQSCIVVI


 


151
QFAGWENTPL LQNIIVHRGQ GVIGHIGQRN NLGHYLMWGI LASAYLNGQR


 


201
KIPAALGAIC LIMQTAVLGL VNSRTILTYI AAIALILPFW YFRSDKSNRR


 


251
TMLGIAAAVF LTALFQFSMN AILETFTGIR YETAVERVAN GGFTDLPRQS


 


301
EWNKALAAFQ SAPIFGHGWN SFAQQTFLIN AEQHTIHDNF LSTLFTHSHN


 


351
IILQLLAEMG ISGTLLVAAT LLTGIAGLLK RSLTPASLFL LCALAVSMCH


 


401
SMLEYPLWYV YFLIPFGLML FLSPAEASDG IAFKKAANLG ILTASAAIFA


 


451
GLLHLDWTYT RLVNSFSPAA DDSAKTLNRK INELRYISAN SPMLSFYADF


 


501
SLVNFALPEY PETQTWAEEA TLKALKYRPY SATYRIALYL MRQGKVAEAK


 


551
QWMRATQSYY PYLMPRYADE IRKLPVWAPL LPELLKDCKA FAAAPGHPET


 


601
KPCK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2517>:










m738.seq




1
ATGCCCGCTG AAACGACCGT ATCCGGCGCG CACCCCGCCG CCAAACTGCC


 


51
GATTTACATC CTGCCCTGCT TCCTTTGGAT AGGCATCGTC CCCTTTACCT


 


101
TCGCGCTCAA ACTGAAACCG TCGCCCGACT TTTACCACGA TGCCGCCGCC


 


151
GCAGCCGGCC TGATTGTCCT GTTGTTCCTC ACGGCAGGAA AAAAACTGTT


 


201
TGATGTCAAA ATCCCCGCCA TCAGCTTCCT TCTGTTTGCA ATGGCGGCGT


 


251
TTTGGTATCT TCAGGCACGC CTGATGAACC TGATTTACCC CGGTATGAAC


 


301
GACATCGTCT CTTGGATTTT CATCTTGCTC GCCGTCAGCG CGTGGGCCTG


 


351
CCGGAGCTTG GTCGCACACT TCGGACAAGA ACGCATCGTG ACCCTGTTTG


 


401
CCTGGTCGCT GCTTATCGGC TCCCTGCTTC AATCCTGCAT CGTCGTCATC


 


451
CAGTTTGCCG GCTGGGAAGA CACCCCTCTG TTTCAAAACA TCATCGTTTA


 


501
CAGCGGGCAA GGCGTAATCG GACACATCGG GCAGCGCAAC AACCTCGGAC


 


551
ACTACCTCAT GTGGGGCATA CTCGCCGCCG CCTACCTCAA CGGACAACGA


 


601
AAAATCCCCG CCGCCCTCGG CGTAATCTGC CTGATTATGC AGACCGCCGT


 


651
TTTAGGTTTG GTCAACTCGC GCACCATCTT GACCTACATA GCCGCCATCG


 


701
CCCTCATCCT TCCCTTCTGG TATTTCCGTT CGGACAAATC CAACAGGCGG


 


751
ACGATGCTCG GCATAGCCGC AGCCGTATTC CTTACCGCGC TGTTCCAATT


 


801
TTCCATGAAC ACCATTCTGG AAACCTTTAC TGGCATCCGC TACGAAACTG


 


851
CCGTCGAACG CGTCGCCAAC GGCGGTTTCA CAGACTTGCC GCGCCAAATC


 


901
GAATGGAATA AAGCCCTTGC CGCCTTCCAG TCCGCCCCGA TATTCGGGCA


 


951
CGGCTGGAAC AGTTTTGCCC AACAAACCTT CCTCATCAAT GCCGAACAGC


 


1001
ACAACATATA CGACAACCTC CTCAGCAACT TGTTCACCCA TTCCCACAAC


 


1051
ATCGTCCTCC AACTCCTTGC AGAGATGGGA ATCAGCGGCA CGCTTCTGGT


 


1101
TGCCGCAACC CTGCTGACGG GCATTGCCGG GCTGCTTAAA CGCCCCCTGA


 


1151
CCCCCGCATC GCTTTTCCTA ATCTGCACGC TTGCCGTCAG TATGTGCCAC


 


1201
AGTATGCTCG AATATCCTTT GTGGTATGTC TATTTCCTCA TCCCTTTCGG


 


1251
ACTGATGCTC TTCCTGTCCC CCGCAGAGGC TTCAGACGGC ATCGCCTTCA


 


1301
AAAAAGCCGC CAATCTCGGC ATACTGACCG CCTCCGCCGC CATATTCGCA


 


1351
GGATTGCTGC ACTTGGACTG GACATACACC CGGCTGGTTA ACGCCTTTTC


 


1401
CCCCGCCACT GACGACAGTG CCAAAACCCT CAACCGGAAA ATCAACGAGT


 


1451
TGCGCTATAT TTCCGCAAAC AGTCCGATGC TGTCCTTTTA TGCCGACTTC


 


1501
TCCCTCGTAA ACTTCGCCCT GCCGGAATAC CCCGAAACCC AGACTTGGGC


 


1551
GGAAGAAGCA ACCCTCAAAT CACTAAAATA CCGCCCCCAC TCCGCCACCT


 


1601
ACCGCATCGC CCTCTACCTG ATGCGGCAAG GCAAAGTTGC AGAAGCAAAA


 


1651
CAATGGATGC GGGCGACACA GTCCTATTAC CCgTACCTGA TGCCCCGATA


 


1701
CGCCGACGAA ATCCGCAAAC TGCCCGTATG GGCGCCGCTG CTACCCGAAC


 


1751
TGCTCAAAGA CTGCAAAGCC TTCGCCGCCG CGCCCGGTCA TCCGGAAGCA


 


1801
AAACCCTGCA AATGA






This corresponds to the amino acid sequence <SEQ ID 2518; ORF 738>:










m738.pep




1
MPAETTVSGA HPAAKLPIYI LPCFLWIGIV PFTFALKLKP SPDFYHDAAA


 


51
AAGLIVLLFL TAGKKLFDVK IPAISFLLFA MAAFWYLQAR LMNLIYPGMN


 


101
DIVSWIFILL AVSAWACRSL VAHFGQERIV TLFAWSLLIG SLLQSCIVVI


 


151
QFAGWEDTPL FQNIIVYSGQ GVIGHIGQRN NLGHYLMWGI LAAAYLNGQR


 


201
KIPAALGVIC LIMQTAVLGL VNSRTILTYI AAIALILPFW YFRSDKSNRR


 


251
TMLGIAAAVF LTALFQFSMN TILETFTGIR YETAVERVAN GGFTDLPRQI


 


301
EWNKALAAFQ SAPIFGHGWN SFAQQTFLIN AEQHNIYDNL LSNLFTHSHN


 


351
IVLQLLAEMG ISGTLLVAAT LLTGIAGLLK RPLTPASLFL ICTLAVSMCH


 


401
SMLEYPLWYV YFLIPFGLML FLSPAEASDG IAFKKAANLG ILTASAAIFA


 


451
GLLHLDWTYT RLVNAFSPAT DDSAKTLNRK INELRYISAN SPMLSFYADF


 


501
SLVNFALPEY PETQTWAEEA TLKSLKYRPH SATYRIALYL MRQGKVAEAK


 


551
QWMRATQSYY PYLMPRYADE IRKLPVWAPL LPELLKDCKA FAAAPGHPEA


 


601
KPCK*






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 738 shows 95.0% identity over a 604 aa overlap with a predicted ORF (ORF738.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2519>:










a738.seq




1
ATGCCCGCTG AAACGACCGT ATCCGGCGCG CACCCCGCCG CCAAACTGCC


 


51
GATTTACATC CTGCCCTGCT TCCTTTGGAT AGGCATCGTC CCCTTTACCT


 


101
TTGCGCTCAG GCTGCAACCG TCGCCCGACT TTTACCACGA TGCCGCCGCC


 


151
GCAGCCGGCC TGATTGTCCT GTTGTTCCTC ACGGCAGGAA AAAAGCTGTT


 


201
TGATGTCAAA ATCCCACCTA TCAGCTTCCT TCTGTTTGCA ATGGCGGCGT


 


251
TTTGGTATCT TCAGGCACGC CTGATGAACC TGATTTACCC CGGTATGAAC


 


301
GACATCGTCT CTTGGATTTT CATCTTACTC GCCGTCAGCG CGTGGGCCTG


 


351
CCGGAGCTTG GTCGCACACT ACGGACAAGA ACGCATCGTT ACCCTGTTTG


 


401
CCTGGTCGCT GCTTATCGGC TCCCTGCTTC AATCCTGCAT CGTCGTCATC


 


451
CAGTTTGCCG GCTGGGAAGA CACCCCTCTG TTTCAAAACA TCATTGTTTA


 


501
CAGCGGGCAA GGCGTAATCG GACACATCGG ACAGCGCAAC AACCTCGGAC


 


551
ACTACCTCAT GTGGGGCATA CTCGCCGCCG CCTACCTCAA CGGACAACGA


 


601
AAAATCCCGC CCGCCTTGGG TGCAATCTGC CTGATTATGC AGACCGCCGT


 


651
TTTAGGTTTG GTCAATTCGC GCACCATCTT GACCTACATA GCCGCCATCG


 


701
CCCTCATCCT TCCCTTCTGG TATTTCCGTT CGGACAAATC CAACAGGCGG


 


751
ACGATACTCG GCATAGCCGC AGCCGTATTC CTTACCGCGC TGTTCCAATT


 


801
TTCCATGAAC ACCATTCTGG AAACCTTTAC CGGCATCCGC TACGAAACCG


 


851
CCGTCGAACG CGTCGCCAAC GGCGGTTTCA CAGACCTGCC GCGCCAAATC


 


901
GAATGGCGCA AAGCCCTCGC CGCCTTCCAG TCCGCCCCGA TATTCGGGCA


 


951
CGGCTGGAAC AGTTTTGCCC AACAAACCTT CCTCATCAAT GCCGAACAGC


 


1001
ACAACATACA CGACAACCTC CTCAGCAACT TGTTCACCCA TTCCCACAAC


 


1051
ATCGTTCTCC AACTCCTTGC AGAGATGGGG ATCAGCGGCA CGCTTCTGGT


 


1101
TGCCGCAACC CTGCTGACGG GCATTGCCGG GCTGCTGAAA CGCCCCCTGA


 


1151
CCCCCGCATC GCTTTTCCTG ATCTGCACAC TTGCCGTCAG TATGTGCCAC


 


1201
AGTATGCTCG AATATCCTTT GTGGTATGTC TATTTCCTCA TCCCCTTCGG


 


1251
ACTGATGCTC TTTCTGTCCC CCGCAGAGGC TTCAGACGGC ATCGCCTTCA


 


1301
AAAAAGCCGC CAATCTCGGC ATACTAACCG CCTCCGCCGC CATATTCGCA


 


1351
GGATTGCTGC ACTTGGACTG GACATACACC CGGATGGTTA ACGCCTTTTC


 


1401
CCCCGCCACT GACGACAGTG CCAAAACCCT CAACCGGAAA ATCAACGAGT


 


1451
TGCGCTATAT TTCCGCAAAC AGTCCGATGC TGTCCTTTTA TGCCGACTTC


 


1501
TCCCTCGTAA ACTTCGCCCT GCCGGAATAC CCCGAAACCC AGACTTGGGC


 


1551
GGAAGAAGCA ACCCTCAAAT CACTAAAATA CCGCCCCCAC TCCGCCACCT


 


1601
ACCGCATCGC CCTCTACCTG ATGCGGCAAG GCAAAGTTGC AGAAGCAAAA


 


1651
CAATGGATGC GGGCGACACA GTCCTATTAC CCCTACCTGA TGCCCCGATA


 


1701
CGCCGACGAA ATCCGCAAAC TGCCCGTATG GGCGCCGCTG CTACCCGAAC


 


1751
TGCTCAAAGA CTGCAAAGCC TTCGCCGCCG CGCCCGGTCA TCCGGAAGCA


 


1801
AAACCCTGCA AATGA






This corresponds to the amino acid sequence <SEQ ID 2520; ORF 738.a>:










a738.pep




1
MPAETTVSGA HPAAKLPIYI LPCFLWIGIV PFTFALRLQP SPDFYHDAAA


 


51
AAGLIVLLFL TAGKKLFDVK IPPISFLLFA MAAFWYLQAR LMNLIYPGMN


 


101
DIVSWIFILL AVSAWACRSL VAHYGQERIV TLFAWSLLIG SLLQSCIVVI


 


151
QFAGWEDTPL FQNIIVYSGQ GVIGHIGQRN NLGHYLMWGI LAAAYLNGQR


 


201
KIPPALGAIC LIMQTAVLGL VNSRTILTYI AAIALILPFW YFRSDKSNRR


 


251
TILGIAAAVF LTALFQFSMN TILETFTGIR YETAVERVAN GGFTDLPRQI


 


301
EWRKALAAFQ SAPIFGHGWN SFAQQTFLIN AEQHNIHDNL LSNLFTHSHN


 


351
IVLQLLAEMG ISGTLLVAAT LLTGIAGLLK RPLTPASLFL ICTLAVSMCH


 


401
SMLEYPLWYV YFLIPFGLML FLSPAEASDG IAFKKAANLG ILTASAAIFA


 


451
GLLHLDWTYT RMVNAFSPAT DDSAKTLNRK INELRYISAN SPMLSFYADF


 


501
SLVNFALPEY PETQTWAEEA TLKSLKYRPH SATYRIALYL MRQGKVAEAK


 


551
QWMRATQSYY PYLMPRYADE IRKLPVWAPL LPELLKDCKA FAAAPGHPEA


 


601
KPCK*






a738/m738 98.3% identity in 604 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2521>:










g739.seq




1
ATGGCAAAAA AACCGAACAA ACCCTTCAGG CTGACCCCCA AACTCCTGAT


 


51
ACGCGCCGTA TTGCTCATCT GTATCACCGC CATCGGCGCA TTGGCAGTAG


 


101
GCATCGTCAG CACATTCAAC CCGAACGGCG ACAAAACCCT CCAAACCGAA


 


151
CCGCAACACA CCGACAGCCC CCGCGAAACC GAATTCTGGC TGCCAAACGG


 


201
CGCCGTCGGA CAAGATGCCG CCCAACCCGA ACACCACCAC GCCGCCTCAT


 


251
CCGAACCCGC ACAGCCGGAC GGCACAGAAG AAAGCGGCAG CGGACTGCCG


 


301
TCCCCTGCCG CACCCAAGAA AAACCGGGTc AAACCGCGCC CTTCGGATGC


 


351
GGCCCGGGCA GCCGATTCGT TAACCGGCAC CGGAACACAA GCTGAAAACA


 


401
CACTCAAAGA AACCCCCGTA CTGCCCACAA ACGCCCCCCA TCCCGAACCC


 


451
CGAAAAGAAA CACCCGAAAA ACAGGCGCAG CCCAAAGAAA CACCCAAAGA


 


501
AAAAGAAACG CCCAAAGAAA ACCATACCAA ACCGGACACC CCGAAAAACA


 


551
CGCCGGCCAA ACCCCATAAA GAGATTCTCG ACAACCTCTT TTGA






This corresponds to the amino acid sequence <SEQ ID 2522; ORF 739>:










g739.pep




1
MAKKPNKPFR LTPKLLIRAV LLICITAIGA LAVGIVSTFN PNGDKTLQTE


 


51
PQHTDSPRET EFWLPNGAVG QDAAQPEHHH AASSEPAQPD GTEESGSGLP


 


101
SPAAPKKNRV KPRPSDAARA ADSLTGTGTQ AENTLKETPV LPTNAPHPEP


 


151
RKETPEKQAQ PKETPKEKET PKENHTKPDT PKNTPAKPHK EILDNLF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2523>:










m739.seq




1
ATGGCAAAAA AACCGAACAA ACCCTTCAGG CTGACCCCCA AACTCCTGAT


 


51
ACGCGCCGTA TTGCTCATCT GTATCGCCGC CATCGGCGCA TTGGCAATAG


 


101
GCATCGTCAG CACATTCAAC CCGAACGGCG ACAAAACCCT TCAAGCCGAA


 


151
CCGCAACACA CCGACAGCCC CCGCGAAACC GAATTCTGGC TGCCAAACGG


 


201
CGTAGTCGGA CAAGATGCCG CCCAACCCGA ACACCACCAC GCCGCCTCAT


 


251
CCGAACCCGC ACAGCCGGAC GGCACAGACG AAAGCGGCAG CGGACTGCCG


 


301
TCCCCTGCCG CACCCAAGAA AAACCGGGTC AAACCGCAAC CTGCCGACAC


 


351
AGCTCAAACC GACAGGCAGC CGGACGACGC CGGAACACAA GCTGAAAACA


 


401
CACTCAAAGA AACCCCCGTA CTGCCCACAA ACGTCCCCCG TCCCGAACCC


 


451
CGAAAAGAAA CACCCGAAAA ACAGGCGCAG CCCAAAGAAA CGCCCAAAGA


 


501
AAACCATACC AAACCGGACA CCCCGAAAAA CACGCCGCCC AAACCCCATA


 


551
AAGAAATTCT CGACAAACTC TTC






This corresponds to the amino acid sequence <SEQ ID 2524; ORF 739>:










m739.pep




1
MAKKPNKPFR LTPKLLIRAV LLICIAAIGA LAIGIVSTFN PNGDKTLQAE


 


51
PQHTDSPRET EFWLPNGVVG QDAAQPEHHH AASSEPAQPD GTDESGSGLP


 


101
SPAAPKKNRV KPQPADTAQT DRQPDDAGTQ AENTLKETPV LPTNVPRPEP


 


151
RKETPEKQAQ PKETPKENHT KPDTPKNTPP KPHKEILDKL F






Computer analysis of the amino acid sequences gave the following results:

Homology with a predicted ORF from N. meningitidis menA with menB

ORF 739 shows 86.3% identity over a 197 aa overlap with a predicted ORF (ORF739.a) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2525>:










a739.seq




1
ATGGCAAAAA AACCGAACAA ACCCTTCAGG CTGACCCCCA AACTCCTGAT


 


51
ACGCGCCGTA TTGCTCATCT GTATCACCGC CATCGGCGCA TTGGCAATAG


 


101
GCATCGTCAG CACATTCAAC CCGAACGGCG ACAAAACCCT CCAAACCGAA


 


151
CCGCAACACA CCGACAGCCC CCGCGAAACC GAATTCTGGC TGCCAAACGG


 


201
CGTAGTCGGA CAAGATGCCG CCCAACCCGA ACACCACCAC GCCTCCTCAT


 


251
CCGCACCCGC ACAGCCGGAC GGCACAGACG AAAGCGGCAG CGGACTGCCG


 


301
TCCCCTGCCG CACCCAAGAA AAACCGGGTC AAACCGCAAC CTGCCGACAC


 


351
AGCTCAAACC GACAGGCAGC CGGACGACGC CGGAGCACAA GCTGAAAACA


 


401
CACTCAAAGA AACCCCCGTA CTGCCCACAA ACGTCCCCCG TCCCGAACCC


 


451
CGAAAAGAAA CACCCGAAAA ACAGGCACAG CCCAAAGAAA CACCCAAAGA


 


501
AAAAGAAACG CCCAAAGAAA ACCATACCAA ACCGGACACC CCGAAAAACA


 


551
CGCCGCCTAA ACCCCATAAA GAAATTCTCG ACAACCTCTT CTGA






This corresponds to the amino acid sequence <SEQ ID 2526; ORF 739.a>:










a739.pep




1
MAKKPNKPFR LTPKLLIRAV LLICITAIGA LAIGIVSTFN PNGDKTLQTE


 


51
PQHTDSPRET EFWLPNGVVG QDAAQPEHHH ASSSAPAQPD GTDESGSGLP


 


101
SPAAPKKNRV KPQPADTAQT DRQPDDAGAQ AENTLKETPV LPTNVPRPEP


 


151
RKETPEKQAQ PKETPKEKET PKENHTKPDT PKNTPPKPHK EILDNLF*






a739/m739 93.9% identity in 197 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2527>:










g740.seq




1
ATGTCCCGAA ACCTGCTTGT CCGCTGGCTC GCCGTCTGCC TCATCCCCTT


 


51
GgcgACGCTT GCCGTTTTCG CCGCCAATcc gcCCGAAGAC AAACCCCAGC


 


101
ATCTGATCAA CGGCATCATC CTTGCCTGCG AAGCGACGTT TTTGTTTAAa


 


151
ttcgtgctCT TTGAAACCAT CAAGCATCAT CTTAaacaag gGTTTGATTT


 


201
GAAACgtcaa ACCATGTTTC TGTTTATTCC GATTGTTTTG CTGGTTGTGT


 


251
ATTTGTTCCA CTATTTCGGC GCGTTTTag






This corresponds to the amino acid sequence <SEQ ID 2528; ORF 740.ng>:










g740.pep




1
MSRNLLVRWL AVCLIPLATL AVFAANPPED KPQHLINGII LACEATFLFK


 


51
FVLFETIKHH LKQGFDLKRQ TMFLFIPIVL LVVYLFHYFG AF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2529>:










m740.seq




1
ATGTCCCGAA ACCTGCTTGT CCGCTGGCTT GCCGTCTGCC TCATCCCGTT


 


51
GGCGACGCTT GCCGTTTTCG CCGCCAATCC GCCCGAAGAC AAACTCCAGC


 


101
ATCTGATCAA CGGCATCATC CTTGCCTGCG AAGCGACGTT TTTGTTTAAA


 


151
TTCGTCCTTT TCGACACCAT CAAGCATCAT TTGAAACAAG AGTTTGATTT


 


201
GAAACGTCAA ACTATGTTGC TGTTTATTCC GATTATTTTG CTGATTGTGT


 


251
ATTTGTTCCA CTATTTTGGC GCGTTTTAG






This corresponds to the amino acid sequence <SEQ ID 2530; ORF 740>:










m740.pep




1
MSRNLLVRWL AVCLIPLATL AVFAANPPED KLQHLINGII LACEATFLFK


 


51
FVLFDTIKHH LKQEFDLKRQ TMLLFIPIIL LIVYLFHYFG AF*






m740/g740 93.5% identity in 92 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2531>:










a740.seq




1
ATGTCCCGAA ACCTGCTTGT CCGCTGGCTT GTCGTCTGCC TGATACCCTT


 


51
GGCGACGCTT GCCGTTTTCG CCGCCAATCC GCCCGAAGAC AAACCCCAGC


 


101
ATCTGATTAA CGGCATCATC CTTGCCTGCG AAGCGACGTT TTTGTTCAAA


 


151
TTCGTCCTTT TCGACACCAT CAAGCATCAT TTGAAACAAG AGTTTGATTT


 


201
GAAACGTCAA ACTATGTTGC TGTTTATTCC GATTATTTTG CTGATTGTGT


 


251
ATTTGTTCCA CTATTTTGGC GCGTTTTAG






This corresponds to the amino acid sequence <SEQ ID 2532; ORF 740.a>:










a740.pep




1
MSRNLLVRWL VVCLIPLATL AVFAANPPED KPQHLINGII LACEATFLFK


 


51
FVLFDTIKHH LKQEFDLKRQ TMLLFIPIIL LIVYLFHYFG AF*






a740/m740 97.8% identity in 92 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2533>:










g741.seq




1
GTGAACCGAA CTACCTTCTG CTGCCTTTCT TTGACCGCCG GCCCTGATTC


 


51
TGACCGCCTG CAGCAGCGGA GGGGCGGAGG CGGTGGTGTC GCCGCCGACA


 


101
TCGGCACGGG GCTTGCCGAT GCATTAACCG CGCCGCTCGA CCATAAAGAC


 


151
AAAGGTTTGA AATCCCTAAC ATTGGAAGCC TCCATTCCCC AAAACGGAAC


 


201
ACTGACCCTG TCGGCACAAG GTGCGGAAAA AACTTTCAAA GCCGGCGGCA


 


251
AAGACAACAG CCTCAACACG GGCAAACTGA AGAACGACAA AATCAGCCGC


 


301
TTCGACTTCG TGCAAAAAAT CGAAGTGGAC GGACAAACCA TCACACTGGC


 


351
AAGCGGCGAA TTTCAAATAT ACAAACAGGA TCACTCCGcc gtcgtTgcCC


 


401
TacgGATTGA AAAAATCAAC AACCCCGACA AAATCGACAG CCTGATAAAC


 


451
CAACGCTCCT TCCTTGTCAG CGATTTGGGC GGAGAACATA CCGCCTTCAA


 


501
CCAACTGCCT GACGGCAAAG CCGAGTATCA CGGCAAAGCA TTCAGCTCCG


 


551
ACGATGCCGA CGGAAAACTG ACCTATACCA TAGATTTCGC CGCCAAACAG


 


601
GGACACGGCA AAATCGAACA CCTGAAAACA CCCGAGCAGA ATGTTGAGCT


 


651
TGCCTCCGCC GAACTCAAAG CAGATGAAAA ATCACACGCC GTCATTTTGG


 


701
GCGACACGCG CTACGGCGGC GAAGAGAAAG GCACTTACCG CCTCGCCCTT


 


751
TTCGGCGACC GCGCCCAAGA AATCGCTGGC TCGGCAACCG TGAAGATAGG


 


801
GGAAAAGGTT CACGAAATCG GCATCGCCGA CAAACAGTAG






This corresponds to the amino acid sequence <SEQ ID 2534; ORF 741.ng>:










g741.pep




1
VNRTTFCCLS LTAGPDSDRL QQRRGGGGGV AADIGTGLAD ALTAPLDHKD


 


51
KGLKSLTLEA SIPQNGTLTL SAQGAEKTFK AGGKDNSLNT GKLKNDKISR


 


101
FDFVQKIEVD GQTITLASGE FQIYKQDHSA VVALRIEKIN NPDKIDSLIN


 


151
QRSFLVSDLG GEHTAFNQLP DGKAEYHGKA FSSDDADGKL TYTIDFAAKQ


 


201
GHGKIEHLKT PEQNVELASA ELKADEKSHA VILGDTRYGG EEKGTYRLAL


 


251
FGDRAQEIAG SATVKIGEKV HEIGIADKQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2535>:










m741.seq




1
GTGAATCGAA CTGCCTTCTG CTGCCTTTCT CTGACCACTG CCCTGATTCT


 


51
GACCGCCTGC AGCAGCGGAG GGGGTGGTGT CGCCGCCGAC ATCGGTGCGG


 


101
GGCTTGCCGA TGCACTAACC GCACCGCTCG ACCATAAAGA CAAAGGTTTG


 


151
CAGTCTTTGA CGCTGGATCA GTCCGTCAGG AAAAACGAGA AACTGAAGCT


 


201
GGCGGCACAA GGTGCGGAAA AAACTTATGG AAACGGTGAC AGCCTCAATA


 


251
CGGGCAAATT GAAGAACGAC AAGGTCAGCC GTTTCGACTT TATCCGCCAA


 


301
ATCGAAGTGG ACGGGCAGCT CATTACCTTG GAGAGTGGAG AGTTCCAAGT


 


351
ATACAAACAA AGCCATTCCG CCTTAACCGC CTTTCAGACC GAGCAAATAC


 


401
AAGATTCGGA GCATTCCGGG AAGATGGTTG CGAAACGCCA GTTCAGAATC


 


451
GGCGACATAG CGGGCGAACA TACATCTTTT GACAAGCTTC CCGAAGGCGG


 


501
CAGGGCGACA TATCGCGGGA CGGCGTTCGG TTCAGACGAT GCCGGCGGAA


 


551
AACTGACCTA CACCATAGAT TTCGCCGCCA AGCAGGGAAA CGGCAAAATC


 


601
GAACATTTGA AATCGCCAGA ACTCAATGTC GACCTGGCCG CCGCCGATAT


 


651
CAAGCCGGAT GGAAAACGCC ATGCCGTCAT CAGCGGTTCC GTCCTTTACA


 


701
ACCAAGCCGA GAAAGGCAGT TACTCCCTCG GTATCTTTGG CGGAAAAGCC


 


751
CAGGAAGTTG CCGGCAGCGC GGAAGTGAAA ACCGTAAACG GCATACGCCA


 


801
TATCGGCCTT GCCGCCAAGC AATAA






This corresponds to the amino acid sequence <SEQ ID 2536; ORF 741>:










m741.pep




1
VNRTAFCCLS LTTALILTAC SSGGGGVAAD IGAGLADALT APLDHKDKGL


 


51
QSLTLDQSVR KNEKLKLAAQ GAEKTYGNGD SLNTGKLKND KVSRFDFIRQ


 


101
IEVDGQLITL ESGEFQVYKQ SHSALTAFQT EQIQDSEHSG KMVAKRQFRI


 


151
GDIAGEHTSF DKLPEGGRAT YRGTAFGSDD AGGKLTYTID FAAKQGNGKI


 


201
EHLKSPELNV DLAAADIKPD GKRHAVISGS VLYNQAEKGS YSLGIFGGKA


 


251
QEVAGSAEVK TVNGIRHIGL AAKQ*






m741/g741 61.4% identity in 280 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2537>:










a741.seq




1
GTGAACCGAA CTGCCTTCTG CTGCCTTTCT TTGACCGCCG CCCTGATTCT


 


51
GACCGCCTGC AGCAGCGGAG GCGGCGGTGT CGCCGCCGAC ATCGGCGCGG


 


101
TGCTTGCCGA TGCACTAACC GCACCGCTCG ACCATAAAGA CAAAAGTTTG


 


151
CAGTCTTTGA CGCTGGATCA GTCCGTCAGG AAAAACGAGA AACTGAAGCT


 


201
GGCGGCACAA GGTGCGGAAA AAACTTATGG AAACGGCGAC AGCCTCAATA


 


251
CGGGCAAATT GAAGAACGAC AAGGTCAGCC GCTTCGACTT TATCCGTCAA


 


301
ATCGAAGTGG ACGGGCAGCT CATTACCTTG GAGAGCGGAG AGTTCCAAGT


 


351
GTACAAACAA AGCCATTCCG CCTTAACCGC CCTTCAGACC GAGCAAGTAC


 


401
AAGATTCGGA GCATTCAGGG AAGATGGTTG CGAAACGCCA GTTCAGAATC


 


451
GGCGATATAG CGGGTGAACA TACATCTTTT GACAAGCTTC CCGAAGGCGG


 


501
CAGGGCGACA TATCGCGGGA CGGCATTCGG TTCAGACGAT GCCAGTGGAA


 


551
AACTGACCTA CACCATAGAT TTCGCCGCCA AGCAGGGACA CGGCAAAATC


 


601
GAACATTTGA AATCGCCAGA ACTCAATGTT GACCTGGCCG CCTCCGATAT


 


651
CAAGCCGGAT AAAAAACGCC ATGCCGTCAT CAGCGGTTCC GTCCTTTACA


 


701
ACCAAGCCGA GAAAGGCAGT TACTCTCTAG GCATCTTTGG CGGGCAAGCC


 


751
CAGGAAGTTG CCGGCAGCGC AGAAGTGGAA ACCGCAAACG GCATACGCCA


 


801
TATCGGTCTT GCCGCCAAGC AGTAA






This corresponds to the amino acid sequence <SEQ ID 2538; ORF 741.a>:










a741.pep




1
VNRTAFCCLS LTAALILTAC SSGGGGVAAD IGAVLADALT APLDHKDKSL


 


51
QSLTLDQSVR KNEKLKLAAQ GAEKTYGNGD SLNTGKLKND KVSRFDFIRQ


 


101
IEVDGQLITL ESGEFQVYKQ SHSALTALQT EQVQDSEHSG KMVAKRQFRI


 


151
GDIAGEHTSF DKLPEGGRAT YRGTAFGSDD ASGKLTYTID FAAKQGHGKI


 


201
EHLKSPELNV DLAASDIKPD KKRHAVISGS VLYNQAEKGS YSLGIFGGQA


 


251
QEVAGSAEVE TANGIRHIGL AAKQ*






a741/m741 95.6% identity in 274 aa overlap





g742.seq not found yet
g742.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2539>:









m742.seq




1
ATGGTTTACG GCATTGCCGA AGCCGATGCG GGCGACAGCA GTGTGCTTAC


 


51
TTTGGGCGGC ATGTATCAGA AGAGTAGGGA GGTTCCTGAT TTTTCGGGCA


 


101
TTATTTTGCC CTGTGAAAAT CAGAAAACTG CCCCGTTCAG TTCAACGCCT


 


151
GCCTGCAACC GGCCTTTGCA ACTGCCGCGC AACACTTATT TGGGGGAGGA


 


201
TTGGTCGCGG TTAAGTGCCG ACAAATACAA CCTTTTCTCA GGATTCAAAC


 


251
ATGTGTTTGA CAACGGTTGG CAGCTCAATG CCGAAGTGTC TTATACCAAG


 


301
AATGAATCCG ATGCGAAGGT GGGGCAGTTT TTTCTGAAAA ACGAATATGC


 


351
GGCGGGTTTG TCGGGTGAGG ATGCGGTAGG CTTTTTGACT GAAAAAAACG


 


401
AAGTCATCCC GTTCGAGCCG AAAGATAAGG CATTGGAGAA ACTGAAAGCA


 


451
TATCGTGATG AAACCGCCAA GGAATACCGG GAGCGCAAAG ACGATTTTGT


 


501
TAAAAACCGT TTCGATAATA CTGCTTTCGA ACAGTATCGC AGCCGCCGTG


 


551
CCGCAGAACG CAAAGCCGGT TTTGACAAGT GTATGAGTGA CCCTTTCGCG


 


601
CTGGACTTTA TCTGTCAAGG TTCTTGGGGG GATCCGGGCG TTGATGCCGA


 


651
CAAGGCGGAA TTTGTCGATA AAGCCCTTGC GAAGGAGGGC ATCTTTAATA


 


701
ATGCGGCACA ACGTTTTCCA AACAGCCTGT ATGACTCTTC CTTTAATCGG


 


751
AAGGCTACCG CCAACCGACG ATACAGTTAT ATGCCGTTGC GGCATACCAA


 


801
AGACGACCGC CAATGGGGAA TTAAACTTGA CCTGACCGGC ACATATGGGC


 


851
TGTTCGGGCG GGAGCATGAT TTCTTTGTCG GCTATGCCTA CGGTGATGAA


 


901
AAGATACGTT CGGAATATCT AGAAATCTAC GAACGCCGCT ACAGAGTACG


 


951
TCCGAATACG GGGGCAACGC ACGGCGTGTA TGCGGGAAGT TGTCAGGAGG


 


1001
AGCCGGACGG CGATTTGTCG TCTCCTTTGG TCAGGGGGCA TAAAGAACCC


 


1051
GATTGGCAGG CGTACGATGA AAAAGGCAAC CGTACCGTTT ATGCCGAAGA


 


1101
ATGCAGGAAC GCCAAGAAAA TAAAAACCGA GCCCAAGCTC GATGCCGAAG


 


1151
GCAAGCAGGT GTATTACTAT GACGAATACA GCGGCAGCCG GACACCGGTA


 


1201
TATGTCGATG TATATGAGCT GGACGAAAAA GGCAACAAGA TTCAGGAGAC


 


1251
CAATCCCGAC GGCACGCCTG CCTTTACCGG TTTTTCCGGT ACGGTGCCGG


 


1301
TTTGGAAAAC CGTCAAAGTG GCAGACGACC ATGTTCCTGC GCTGTATAAC


 


1351
TACGCCAAAT ACCTCAACAC CAACAAAACC CATTCGCTGA CTGCCAGCAC


 


1401
GCGTTTCAAC GTAACCGGCC GACTGCACCT TTTGGGCGGG CTGCACTACA


 


1451
CGCGCTATGA GACTTCGCAA ACCAAAGATA TGCCTGTCCG CTATGGGCAG


 


1501
CCGGCAAGCG ATTTTCAGAC GGCATCGAGC ATTAGGGCGG ATCAGGACCA


 


1551
TTACACGGCC AAGATGCAAG GTCATAAATT GACGCCCTAT GCAGGCATTA


 


1601
CCTATGACTT GACACCGCAA CAGAGTATTT ACGGAAGTTA TACCAAAATC


 


1651
TTCAAACAGC AGGATAATGT CGATGTCAGT GCCAAAACCG TTTTACCGCC


 


1701
TTTGGTCGGC ACAAACTATG AGGTAGGCTG GAAAGGCGCG TTCTTGCAAG


 


1751
GACGGCTGAA TGCTTCGTTC GCATTGTTTT ACCTCGAACA GAAAAACCGC


 


1801
ACGGTCGTCG ATTTCGGCTA TGTTCCCGGA GCAGGCGGCA AGCAGGGGTC


 


1851
GTTCCAAACC GTTGCCAAAC CGATAGGCAA AGTGGTCAGC AGGGGTGCGG


 


1901
AATTCGAGTT GTCGGGTGAG TTGAACGAAG ATTGGAAAGT CTTTGCGGGT


 


1951
TACACCTACA ACAAGAGCCG CTACAAAAAC GCCGCCGAAG TCAACGCCGA


 


2001
ACGCCTTGCC AAAAATTCCA GTGCAGACCC GTACAACTTC AGCAATTTCA


 


2051
CACCCGTGCA CATATTCCGT TTCGGAACGA GCTTCCATAT ACCGAATACG


 


2101
GGGCTGACCG TCGGCGGCGG CGTGTCCGCA CAAAGCGGCA CAAGCAGTCT


 


2151
GTATAACATC AGGCAGGGCG GCTACGGGCT GATAGACGGT TTCGTCCGTT


 


2201
ACGAATTGGG CAAACACGCC AAATTGAGCC TCATCGGTAC GAACTTAAAC


 


2251
GGACGCACTT ATTTTGAGAA CAACTACAAC CGTACGCGCG GCGCAAACAA


 


2301
CTTCTACGGA GAGCCGCGCA CTGTCAGCAT GAAACTGGAT TGGCAGTTTT


 


2351
AA






This corresponds to the amino acid sequence <SEQ ID 2540; ORF 742>:










m742.pep




1
MVYGIAEADA GDSSVLTLGG MYQKSREVPD FSGIILPCEN QKTAPFSSTP


 


51
ACNRPLQLPR NTYLGEDWSR LSADKYNLFS GFKHVFDNGW QLNAEVSYTK


 


101
NESDAKVGQF FLKNEYAAGL SGEDAVGFLT EKNEVIPFEP KDKALEKLKA


 


151
YRDETAKEYR ERKDDFVKNR FDNTAFEQYR SRRAAERKAG FDKCMSDPFA


 


201
LDFICQGSWG DPGVDADKAE FVDKALAKEG IFNNAAQRFP NSLYDSSFNR


 


251
KATANRRYSY MPLRHTKDDR QWGIKLDLTG TYGLFGREHD FFVGYAYGDE


 


301
KIRSEYLEIY ERRYRVRPNT GATHGVYAGS CQEEPDGDLS SPLVRGHKEP


 


351
DWQAYDEKGN RTVYAEECRN AKKIKTEPKL DAEGKQVYYY DEYSGSRTPV


 


401
YVDVYELDEK GNKIQETNPD GTPAFTGFSG TVPVWKTVKV ADDHVPALYN


 


451
YAKYLNTNKT HSLTASTRFN VTGRLHLLGG LHYTRYETSQ TKDMPVRYGQ


 


501
PASDFQTASS IRADQDHYTA KMQGHKLTPY AGITYDLTPQ QSIYGSYTKI


 


551
FKQQDNVDVS AKTVLPPLVG TNYEVGWKGA FLQGRLNASF ALFYLEQKNR


 


601
TVVDFGYVPG AGGKQGSFQT VAKPIGKVVS RGAEFELSGE LNEDWKVFAG


 


651
YTYNKSRYKN AAEVNAERLA KNSSADPYNF SNFTPVHIFR FGTSFHIPNT


 


701
GLTVGGGVSA QSGTSSLYNI RQGGYGLIDG FVRYELGKHA KLSLIGTNLN


 


751
GRTYFENNYN RTRGANNFYG EPRTVSMKLD WQF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2541>:










a742.seq




1
ATGGTTTACG GCATTGCCGA AGCCGATGCG GGCGACAGCA GTGTGCTTAC


 


51
TTTGGGCGGC ATGTATCAGA AGAGTAGGGA GGTTCCTGAT TTTTCGGGCA


 


101
TTATTTTGTC CTGTGAAAAT CAGAAAACTG CCCCGTTCAG TTCAACGCCT


 


151
GCCTGCAACC GGCCTTTGCA ACTGCCGCGC AACACTTATT TGGGGGAGGA


 


201
TTGGTCGCGG TTGAGTGCTG ACAAATACAA CCTTTTCTCA GGTTTCAAAC


 


251
ATGTGTTTGA CAACGGTTGG CAGCTCAATG CCGAAGTGTC TTATACCAAG


 


301
AATGAATCCG ATGCGAAGGT GGGGCAGTTT TTTCTGAAAA ACGAACATGC


 


351
GGCGGGTTTG TCAGATGAGG ATGCGGTAGG CTTTTTGACC GAAAAAAACG


 


401
AAGTCATCCC GTTCGAGCCG AAAGATAAGG CATTGGAGAA ACTGAAAGCA


 


451
TATCGTGACG AAACCGCCAA GGAATACCGT GAGCGCAAAG ACGATTTTGT


 


501
TAAAAACCGT TTCGATAATA CTGCTTTCGA GCAGTACCGC AGCCGCCGTG


 


551
CCGCAGAACG CAAAGCCGGT TTTGACGAGT GTATGAGTGC CCCTTTTGCG


 


601
CTGGACTTTA TCTGTCAAGG TTCTTGGGGG GATCCGGGTG TTGATGCCGA


 


651
CAAGTCGGAA TTTGTCGATA AAGCCCTTGC GAAGGAAGGC ATCTTTAATA


 


701
ATGCGGCACA ACGTTTTCCA AACAGCCTGT ATGACTCTTC CTTTAATCGG


 


751
AAGGCTACCG CCAACCGACG ATACAGTTAT ATGCCGTTGC GGCATACCAA


 


801
AGACGACCGC CAATGGGGAA TTAAACTTGA CCTGACCGGC ACATATGGGC


 


851
TGTTCGGGCG GGAGCATGAT TTCTTTGTCG GCTATGCCTA CGGCGATGAA


 


901
AAGATACGTT CCGAATATCT GGAAATCTAC GAACGCCGCC ACAGAGTACG


 


951
TCCGAATACA GGGGCAACGC ACGGCGTGTA TGCGGGAAGT TGTCAGGGGG


 


1001
AGCCGGACGG TGATTTGTCT TCTCCTTTGG TCAGGGGGCA TAAAGAACCC


 


1051
GATTGGCAGG CGTACGATGA AAAAGGCAAC CGTACCGTTT ATGCCGAAGA


 


1101
ATGCAGGAAT GCCAAGAAAA TAAAAACCGA GCCCAAGCTC GATGCCGAAG


 


1151
GCAAGCAGGT GTATTACTAT GACGAATACA GCGGCAGCCG GACGCCAGTA


 


1201
TATGTCGATG TATATGAACT GGATGAAAAA GGCAATAAGA TTCAGGAGAC


 


1251
CAATCCCGAC GGCACGCCTG CCTTTACCGG TTTTTCCGGT ACGGTGCCGG


 


1301
TTTGGAAAAC CGTCAAAGTG GCCGACGACC ATGTTCCTGC GCTGTATAAC


 


1351
TACGCCAAAT ACCTCAACAC CAACAAAACC CATTCGCTGA CTGCCGGCAC


 


1401
GCGTTTCAAC GTAACCGGCC GACTGCATCT TTTGGGCGGG CTGCACTACA


 


1451
CGCGCTATGA AACCTCGCAA ACCAAAGATA TGCCTGTCCG CTATGGGCAG


 


1501
CCGGCAAGCG ATTTTCAGAC GGCATCGAGC ATTAAGGCGG ATCAGGACCA


 


1551
TTATACGGCC AAGATGCAAG GTCATAAATT GACGCCCTAT GCAGGCATTA


 


1601
CCTATGATTT GACACCGCAA CAGAGTATTT ACGGAAGTTA TACCAAAATC


 


1651
TTCAAACAGC AGGATAATGT CGATGTCAGT GCCAAAACCG TTTTACCGCC


 


1701
TTTGGTCGGC ACAAACTATG AGGTAGGCTG GAAAGGCGCG TTCTTGCAAG


 


1751
GACGGCTGAA TGCTTCGTTC GCATTGTTTT ACCTCGAACA GAAAAACCGC


 


1801
ACGGTCGTCG ATTTTGGCTA TGTTCCCGGA GCAGGCGGCA AGCAGGGGTC


 


1851
GTTCCAAACC GTTGCCAAAC CGATAGGCAA AGTGGTCAGC AGGGGTGCGG


 


1901
AATTCGAGTT GTCGGGTGAG TTGAACGAAG ATTGGAAAGT CTTTGCGGGT


 


1951
TACACCTACA ACAAGAGCCG CTACAAAAAC GCCGCCGAAG TCAACGCCGA


 


2001
ACGCCTCGCC AAAAACACAG GCGCAGACCC GTACAACTTC AGCAATTTCA


 


2051
CACCCGTGCA CATATTCCGT TTCGGAACGA GCTTCCATAT ACCGAATACG


 


2101
GGGCTGACCG TCGGCGGCGG CGTGTCCGCA CAAAGCGGCA CAAGCAGTCT


 


2151
GTATAACATC AGGCAGGGCG GCTACGGGCT GATAGACGGT TTCGTCCGTT


 


2201
ACGAATTGGG CAAACACGCT AAATTGAGCC TCATCGGTAC GAACTTAAAC


 


2251
GGACGCACTT ATTTTGAGAA CAACTACAAC CGTACGCGCG GCGCAAACAA


 


2301
CTTCTATGGA GAGCCGCGCA CTGTCAGCAT GAAACTGGAT TGGCAGTTTT


 


2351
AA






This corresponds to the amino acid sequence <SEQ ID 2542; ORF 742.a>:










a742.pep




1
MVYGIAEADA GDSSVLTLGG MYQKSREVPD FSGIILSCEN QKTAPFSSTP


 


51
ACNRPLQLPR NTYLGEDWSR LSADKYNLFS GFKHVFDNGW QLNAEVSYTK


 


101
NESDAKVGQF FLKNEHAAGL SDEDAVGFLT EKNEVIPFEP KDKALEKLKA


 


151
YRDETAKEYR ERKDDFVKNR FDNTAFEQYR SRRAAERKAG FDECMSAPFA


 


201
LDFICQGSWG DPGVDADKSE FVDKALAKEG IFNNAAQRFP NSLYDSSFNR


 


251
KATANRRYSY MPLRHTKDDR QWGIKLDLTG TYGLFGREHD FFVGYAYGDE


 


301
KIRSEYLEIY ERRHRVRPNT GATHGVYAGS CQGEPDGDLS SPLVRGHKEP


 


351
DWQAYDEKGN RTVYAEECRN AKKIKTEPKL DAEGKQVYYY DEYSGSRTPV


 


401
YVDVYELDEK GNKIQETNPD GTPAFTGFSG TVPVWKTVKV ADDHVPALYN


 


451
YAKYLNTNKT HSLTAGTRFN VTGRLHLLGG LHYTRYETSQ TKDMPVRYGQ


 


501
PASDFQTASS IKADQDHYTA KMQGHKLTPY AGITYDLTPQ QSIYGSYTKI


 


551
FKQQDNVDVS AKTVLPPLVG TNYEVGWKGA FLQGRLNASF ALFYLEQKNR


 


601
TVVDFGYVPG AGGKQGSFQT VAKPIGKVVS RGAEFELSGE LNEDWKVFAG


 


651
YTYNKSRYKN AAEVNAERLA KNTGADPYNF SNFTPVHIFR FGTSFHIPNT


 


701
GLTVGGGVSA QSGTSSLYNI RQGGYGLIDG FVRYELGKHA KLSLIGTNLN


 


751
GRTYFENNYN RTRGANNFYG EPRTVSMKLD WQF*






a742/m742 98.5% identity in 783 aa overlap





a742/p25184








sp|P25184|PUPA_PSEPU FERRIC-PSEUDOBACTIN 358 RECEPTOR PRECURSOR



>gi|949231|pir||S15169


ferric-pseudobactin receptor precursor - Pseudomonas putida


>gi|45723 (X56605)


pseudobactin uptake protein [Pseudomonas putida]Length = 819


Score = 152 bits (381), Expect = 6e−36


Identities = 110/356 (30%), Positives = 170/356 (46%),


Gaps = 55/356 (15%)











Query:
436
KTVKVADDHV-PALYNYAKYLNTNKTHSLTAGTRFNVTGRLHLLGGLHYTRYETSQTKDM
494





+T K  DD + P +    +Y  +N+       +RFN+T  LHL+ G   + Y


Sbjct:
511
QTPKPGDDEIIPGIQYNISNRQSGYFVASRFNLTDDLHLILGARASNYRFDYAL--
564


 


Query:
495
PVRYGQPASDFQTASSIKADQDHYTAKMQGHKLTPYAGITYDLTPQQSIYGSYTKIFKQQ
554




  R G   + ++               ++   +TPYAGI YDLT +QS+Y SYT IFK Q


Sbjct:
565
-WRIGNEPAPYKMVERGVVTPYAGIVYDLTNEQSVYASYTDIFKPQ
609


 


Query:
555
DNVDVSAKTVLPPLVGTNYEVGWKGAFLQGRLNASFALFYLEQKNRTVVDFGYVPGAGGK
614




+NVD++ K  L P VG NYE+GWKG FL+GRLNA+ AL+ +++ N        VP +GG


Sbjct:
610
NNVDITGKP-LDPEVGKNYELGWKGEFLEGRLNANIALYMVKRDNLAESTNEVVPDSGGL
668


 


Query:
615
QGSFQTVAKPIGKVVSRGAEFELSGELNEDWKVFAGYTYNKSRYKNAAEVNAERLAKNTG
674




  S     + +    ++G + ELSGE+   W VF GY++ ++


Sbjct:
669
IAS-----RAVDGAETKGVDVELSGEVLPGWNVFTGYSHTRTE----------------D
707


 


Query:
675
ADPYNFSNFTPVHIFRFGTSFHIPN--TGLTVGGGVSAQSGTSSLYN--IRQGGYGL
727




AD    +   P+  FRF  ++ +P     LT+GGGV+  S ++   + YN  + Q  Y +


Sbjct:
708
ADGKRLTPQLPMDTFRFWNTYRLPGEWEKLTLGGGVNWNSKSTLNFARYNSHVTQDDYFV
767


 


Query:
728
IDGFVRYELGKHAKLSLIGTNLNGRTYFENNYNRTRGANNFYGEPRTVSMKLDWQF
783




     RY + +    +L   N+  + Y    Y    G+   YG PR  ++ L + F


Sbjct:
768
TSLMARYRINESLAATLNVNNIFDKKY----YAGMAGSYGHYGAPRNATVTLRYDF
819






g743.seq not found yet
g743.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2543>:









m743.seq




1
ATGAATCAAA ATCATTTTTC ACTTAAAATT CTGACCGTTA TGCTGTTATC


 


51
GGCTTACGGT GGTTCTTTTG CAGACGGTGT TGTGCCTGTT TCAGACGGCA


 


101
ATACCGTCAG TCTGGATACG GTCAATGTAC GCGGCTCTCA TGCTTTGTTG


 


151
GGCAAGACCG AAAAGACCCG TTCTTATACG ATAGATCGGA TGTCCACCGC


 


201
CACAGGTATG AGGATTGCGG GCAAGGATAC GCCGCAGTCG GTCAGCGTCA


 


251
TCACGCGCAG CCGCCTTGAC GATAAGGCGG TGCATACGCT TGAAGAGGCA


 


301
ATGAAAAACA CGACGGGTGT CAACGTTGTG CGCGATTCAG GCTTGCAGAC


 


351
GCGGTTTTTG TCACGCGGTT TCTATATTGA TCAGATTGGT GAAGACGGTA


 


401
TGACCGTCAA TGTTGCAGGC CGTTCGGGAT ATACGGCGAA AATCGACGTG


 


451
TCTCCGAGTA CCGATTTGGC GGTTTATGAC CATATTGAAG TTGTACGGGG


 


501
TGCAACGGGG TTGACCCAAT CCAATTCAGA GCCGGGAGGA ACCGTCAATT


 


551
TGATCCGTAA GTGA






This corresponds to the amino acid sequence <SEQ ID 2544; ORF 743>:










m743.pep




1
MNQNHFSLKI LTVMLLSAYG GSFADGVVPV SDGNTVSLDT VNVRGSHALL


 


51
GKTEKTRSYT IDRMSTATGM RIAGKDTPQS VSVITRSRLD DKAVHTLEEA


 


101
MKNTTGVNVV RDSGLQTRFL SRGFYIDQIG EDGMTVNVAG RSGYTAKIDV


 


151
SPSTDLAVYD HIEVVRGATG LTQSNSEPGG TVNLIRK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2545>:










a743.seq




1
ATGAATCAAA ATCATTTTTC ACTTAAAATT CTGACCGTTA TGCTGTTATC


 


51
GGCTTACGGT GGTTCTTTTG CAGACGGTGT TGTGCCTGTT TCAGACGGCA


 


101
ATACCGTCAG TTTGGATACG GTCAATGTAC GCGGCTCTCA TGCTCTGTCG


 


151
GGCAAGACCG AGAAGACCCG TTCTTATACG ATAGATCGGA TGTCCACCGC


 


201
CACAGGTATG AGGATTGCGG GCAAGGATAC GCCGCAGTCG GTCAGCGTCA


 


251
TCACGCGCAG CCGCCTTGAC GATAAGGCGG TGCATACGCT TGAAGAGGCA


 


301
ATGAAAAACA CGACGGGTGT CAACGTTGTG CGCGATTCAG GCTTGCAGAC


 


351
GCGGTTTTTG TCACGCGGTT TCTATATTGA TCAGATTGGT GAAGACGGTA


 


401
TTACCGTCAA TGTTGCAGGC CGTTCGGGAT ATACGGCGAA AATCGACGTG


 


451
TCTCCGAGTA CCGATTTGGC GGTTTATGAC CATATTGAAG TTGTACGGGG


 


501
TGCAACGGGG TTGACCCAAT CCAATTCAGA GCCGGGTGGA ACCGTCAATT


 


551
TGATCCGTAA GCGA






This corresponds to the amino acid sequence <SEQ ID 2546; ORF 743.a>:










a743.pep




1
MNQNHFSLKI LTVMLLSAYG GSFADGVVPV SDGNTVSLDT VNVRGSHALS


 


51
GKTEKTRSYT IDRMSTATGM RIAGKDTPQS VSVITRSRLD DKAVHTLEEA


 


101
MKNTTGVNVV RDSGLQTRFL SRGFYIDQIG EDGITVNVAG RSGYTAKIDV


 


151
SPSTDLAVYD HIEVVRGATG LTQSNSEPGG TVNLIRKR






a743/m743 98.9% identity in 187 aa overlap





g744.seq not found yet

g744.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2547>:










m744.seq




1
ATGAAACCGT TAAAAACATT AGAATTTGGA TTTGTGGATG CTGCAAACTA


 


51
CAGAAGAAGA GAAAATAAAG ATTTATTTAA CCGAATATTT GTAAAAGGAG


 


101
AATATTTGGA TGAATTATGT GAACCAAATA TTTCGTTTTT AATCGGAGAA


 


151
AAGGGAACTG GAAAGACAGC ATATGCTGTT TATTTAACTA ATAACTTCTA


 


201
TAAAAACATA CATGCCACTA CTAAGTTTGT TCGTGAAACC GATTATTCAA


 


251
AATTTATTCA GCTAAAGAAA GCAAGACACT TAACTGTTTC AGATTTTACA


 


301
AGTATTTGGA AAGTCATTTT ATATCTGTTG ATATCAAATC AAATCAAATG


 


351
TAAAGAAAAC GGAATATTAT CTTCAATATT TAATAAATTT AAAGCCTTAG


 


401
ATGAGGCTAT AAATGAATAT TATTATGGCG CTTTTGATCC GGAAATTGTA


 


451
CAAGCAATAA CTTTAATAGA AAATTCAAAA GAAGCTGCGG AAATGATTTT


 


501
TGGAAAATTT GTTAAACTAG GTGAAGAGGA ATCCCAACAA ATAACTTTTA


 


551
CAGAAAGTAA ATTCCAAGCA AATTTAGGTT TTATTGAAAG AAAATTTAAA


 


601
GATGCTTTAT CTCAGTTAAA GCTAAAAGAT AATCATATTT TGTTTATTGA


 


651
TGGGATAGAT ATTAGACCAT CACAGATTCC ATTTGATGAA TATCATGAGT


 


701
GTGTAAAAGG TCTTGCTAAC GCCATATGGA TGTTAAATAA TGATATCTTC


 


751
CCTTCCATTA AAGATAGTAA GGGAAGGATG AGAGTTGTGT TATTGATTAG


 


801
ACCTGATATC TTTGATTCAT TAGGTTTACA AAATCAAAAT ACCAAACTTC


 


851
AAGATAATTC AGTATTTTTA GACTGGAGGA CGGATTATAA ATCTTATAGA


 


901
AGTTCAAAGA TTTTTGGCGT TTTTGATCAT CTTTTGAGAA CCCAGCAAGA


 


951
AAAACAAGAT AGTTTAGAAA AAGGCAACTC ATGGGATTAT TATTTTCCAT


 


1001
GGAATGCTCC TAATTTACAT GATGAGTATA AAAATTTAAC TTCATTTATT


 


1051
AGCTTCCTAA GAAAATCGTA TTATCGACCT CGCGATATTC TTCAGATGCT


 


1101
TACTTTGCTA CAAAAAAATA AGAAAAGTAA GGAAGATTAT GTCGTAGCAG


 


1151
AAGATTTTGA TAATACTTCT TTTCAAAGAG AATACTCGAT ATATTTACTT


 


1201
GGTGAAATCA AAGATCATCT TTTGTTTTAT TATAGTCAAA GTGATTATCA


 


1251
AAATTTCCTG AAATTTTTTG AATTTTTAAA CGGGAAAGAT AGATTTAAAT


 


1301
ATAGTGATTT TTTAAAAGCA TTTGAACGTT TGAAAAAGCA CTTACAAACA


 


1351
ACATCAGTGG AAATACCTAA ATTTATGAGT ACTGCTAATG AGTTTTTGCA


 


1401
ATTTTTATTT GACTTGAATG TTATTGCTTA TTTAGATAAC CCAGAAGATG


 


1451
AAACGAAACC ATATATCCAT TGGTGCTTTA AAGATAGAAA TTATGCAAAT


 


1501
ATTTCTCCTA AAATAAAAAC TGAAACTGAA TATTTAATAT TTTCAGGATT


 


1551
ATCAAAAGCC CTTGATGTTG GTACTCCATT TAAGAACAAA CAGTAA






This corresponds to the amino acid sequence <SEQ ID 2548; ORF 744>:










m744.pep




1
MKPLKTLEFG FVDAANYRRR ENKDLFNRIF VKGEYLDELC EPNISFLIGE


 


51
KGTGKTAYAV YLTNNFYKNI HATTKFVRET DYSKFIQLKK ARHLTVSDFT


 


101
SIWKVILYLL ISNQIKCKEN GILSSIFNKF KALDEAINEY YYGAFDPEIV


 


151
QAITLIENSK EAAEMIFGKF VKLGEEESQQ ITFTESKFQA NLGFIERKFK


 


201
DALSQLKLKD NHILFIDGID IRPSQIPFDE YHECVKGLAN AIWMLNNDIF


 


251
PSIKDSKGRM RVVLLIRPDI FDSLGLQNQN TKLQDNSVFL DWRTDYKSYR


 


301
SSKIFGVFDH LLRTQQEKQD SLEKGNSWDY YFPWNAPNLH DEYKNLTSFI


 


351
SFLRKSYYRP RDILQMLTLL QKNKKSKEDY VVAEDFDNTS FQREYSIYLL


 


401
GEIKDHLLFY YSQSDYQNFL KFFEFLNGKD RFKYSDFLKA FERLKKHLQT


 


451
TSVEIPKFMS TANEFLQFLF DLNVIAYLDN PEDETKPYIH WCFKDRNYAN


 


501
ISPKIKTETE YLIFSGLSKA LDVGTPFKNK Q*






g745.seq not found yet
g745.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2549>:









m745.seq




1
ATGTTTTGGC AACTGACCGT TGTTTCAGTA ACCGCCGTCA TTGCACTGGG


 


51
GACAATATTC ATCAATAAGA AAACTTCAAA GCAAAAGGCG ACATTAGATG


 


101
TTATTTTGAA TGATTACCAA GATGCACAAT TTGTAGAAGC CGACAATCAT


 


151
ATTTCGCCTT ATATTCGCGG CACGGCAGTT GACGACAACA ACGCGCGGAT


 


201
CGACCTGTAT GAAATTTATC AAAATAAGGG CGGACAATGG GAAAAAGAGA


 


251
GAGGGCATTT ACTTACCGTA ATCAATCGGC ACGAGTTTTA TGCGTGCGCA


 


301
ATCAACTCGG GAGTATTGGA TGAGGATTTG TTTAAACGGC TGCATTGCAC


 


351
CAACTTCATA AAATTGTGGA ATGCAGTTTC GCCTCTTGTT ATGAAAATAC


 


401
GCGAAGAAGA ACGCAAAGAC ACAATATTTA GAGAGTTGGA AATTTTGGTT


 


451
GCATTATGGA AAGCAAACCC CCTAAAGGCA TCTGATTTGT GA






This corresponds to the amino acid sequence <SEQ ID 2550; ORF 745>:










m745.pep




1
MFWQLTVVSV TAVIALGTIF INKKTSKQKA TLDVILNDYQ DAQFVEADNH


 


51
ISPYIRGTAV DDNNARIDLY EIYQNKGGQW EKERGHLLTV INRHEFYACA


 


101
INSGVLDEDL FKRLHCTNFI KLWNAVSPLV MKIREEERKD TIFRELEILV


 


151
ALWKANPLKA SDL*






a745.seq not found yet
a745.pep not found yet
The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2551>:









g746.seq




1
ATGTCCGAAA ACAAACAAAA CGAAGTCCTG ACCGGTTACG AACAGCTGAA


 


51
ACGGCGCAAC CGCCGCCGCC TCGTAACGGC AAGCTCCCTG GTTGCCGCCT


 


101
CCTGCATCCT GCTGGCAGCC GCACTCAGTT CCGATCCTGC CGACAGCAAT


 


151
CCCGCACCGC AGGCCGGCGA AACCGGCGCA ACGGAAAGCC AAACGGCAAA


 


201
CACGGCACAA ACCCCTGCCT TGAAATCCGC CGCCGAAAAC GGGGAAACCG


 


251
CCGCCGACAA ACCGCAGGAC TTGGCAGGCG AAGACAAGCC TTCTGCCGCC


 


301
GACAGCGAAA TCAGCGAGCC TGAAAACGTA GGCGCGCCGC TGGTGCTGAT


 


351
TAACGACCGG CTCGAAGACA GCAACATCAA AGGTTTGGAA GAATCCGAGA


 


401
AACTGCAACA GGCAGAAACC GCCAAAACCG AACCGAAGCA GGCAAAACAA


 


451
CGCGCTGCCG AAAAAGTGTC GGCAACTGCC GACAGTACGG ATACGGTAGC


 


501
GGTTGAAAAA CCGAAACGCA CTGCCGAACC CAAACCGCAA AAAGCGGAAC


 


551
GCACTGCCGA AGCCAAGCCC AAAGCCAAAG AAACCAAAAC CGCCGAAAAA


 


601
GTTGCCGACA AACCGAAAAC TGCTGCCGAA AAAACCAAAC CGGATACGGC


 


651
AAAATCCGAC AGCGCGGTAA AAGAAGCGAA AAAAGCCGAC AAGGCTGAAG


 


701
GCAAAAAGAC AGCCGAAAAA GACCGTTCGG ACGGCAAAAA ACACGAAACG


 


751
GCGCAAAAAA CCGACAAAGC GGACAAAACC AAAACCGCCG AGAAGGAAAA


 


801
ATCCGGCAAG GCGGGCAAAA AAGCCGCCAT TCAGGCAGGT TATGCCGAAA


 


851
AAGAACGCGC CTTGAGCCTC CAGCGCAAAA TGAAGGCGGC GGGTATCGAT


 


901
TCGACCATCA CCGAAATCAT GACCGACAAC GGCAAAGTTT ACCGCGTCAA


 


951
ATCAAGCAAC TATAAAAACG CAAGGGATGC CGAACGCGAT TTGAACAAAC


 


1001
TGCGCGTGCA CGGCATCGCC GGCCAGGTAA CGAATGAATA G






This corresponds to the amino acid sequence <SEQ ID 2552; ORF 746.ng>:










g746.pep




1
MSENKQNEVL TGYEQLKRRN RRRLVTASSL VAASCILLAA ALSSDPADSN


 


51
PAPQAGETGA TESQTANTAQ TPALKSAAEN GETAADKPQD LAGEDKPSAA


 


101
DSEISEPENV GAPLVLINDR LEDSNIKGLE ESEKLQQAET AKTEPKQAKQ


 


151
RAAEKVSATA DSTDTVAVEK PKRTAEPKPQ KAERTAEAKP KAKETKTAEK


 


201
VADKPKTAAE KTKPDTAKSD SAVKEAKKAD KAEGKKTAEK DRSDGKKHET


 


251
AQKTDKADKT KTAEKEKSGK AGKKAAIQAG YAEKERALSL QRKMKAAGID


 


301
STITEIMTDN GKVYRVKSSN YKNARDAERD LNKLRVHGIA GQVTNE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2553>:










m746.seq




1
ATGTCCGAAA ACAAACAAAA CGAAGTCCTG AGCGGTTACG AACAACTCAA


 


51
ACGGCGCAAC CGCCGCCGCC TCGTAACGGC AAGTTGCCTG GTTGCCGCCT


 


101
CCTGCATCCT GCTGGCAGCC GCCCTCAGTT CCGGCCCTGC CGAACAGACT


 


151
GCCGGCGAAA CAAGCGGCGT AGAAAACAAA GCGGCAGGTG CGGCACAAAC


 


201
CCCTGCCTTG AAATCCGCCG CCGACAAACC GCAGGACTTG GCAGGCGAAG


 


251
ACAAGCCTTC TGCCGCCGAC AGCGAAATCA GCGAGCCTGA AAACGTAGGC


 


301
GCGCCGCTGG TGCTGATTAA CGAGCGCCTC GAAGACAGCA ACATCAAAGG


 


351
TTTGGAAGCA TCCGAGAAAC TGCAACAGGC AGAAACCGCC AAAACCGCAC


 


401
CGAAGCAGGC AAAACAACGC GCTGCCGAAA AAGTGCCGGC AACTGCCGAC


 


451
AGTACGGATA CGGTAGCGGT TGAAAAACCG AAACGCACTG CCGAAACAAA


 


501
ACCGCAAAAA GCGGAACGCA CTGCCAAAGC CAAGCCCAAA GCCAAAGAAA


 


551
CCAAAACCGC CGAAAAAGTT GCCGACAAAC CGAAAACTGC CGCCGAAAAA


 


601
ACCAAACCGG ATACGGCAAA ATCCGACAGC GCGGTAAAAG AAGCGAAAAA


 


651
AGCCGACAAG GCTGAAAGCA AAAAAACAGC CGAAAAAGAC CGTTCGGACG


 


701
GCAAAAAACA CGAAACGGCA CAAAAAACCG ACAAAGCGGA CAAGACCAAA


 


751
ACCGCCGAGA AGGAAAAATC CGGTAAAAAA GCCGCCATTC AGGCAGGTTA


 


801
TGCCGAAAAA GAACGCGCCT TAAGCCTCCA GCGCAAAATG AAGGCGGCGG


 


851
GTATCGATTC GACCATCACC GAAATTATGA CCGACAACGG CAAAGTTTAC


 


901
CGCGTCAAAT CAAGCAACTA TAAAAACGCA AGGGATGCCG AACGCGATTT


 


951
GAACAAATTG CGCGTACACG GTATCGCCGG TCAGGTAACG AATGAATAG






This corresponds to the amino acid sequence <SEQ ID 2554; ORF 746>:










m746.pep




1
MSENKQNEVL SGYEQLKRRN RRRLVTASCL VAASCILLAA ALSSGPAEQT


 


51
AGETSGVENK AAGAAQTPAL KSAADKPQDL AGEDKPSAAD SEISEPENVG


 


101
APLVLINERL EDSNIKGLEA SEKLQQAETA KTAPKQAKQR AAEKVPATAD


 


151
STDTVAVEKP KRTAETKPQK AERTAKAKPK AKETKTAEKV ADKPKTAAEK


 


201
TKPDTAKSDS AVKEAKKADK AESKKTAEKD RSDGKKHETA QKTDKADKTK


 


251
TAEKEKSGKK AAIQAGYAEK ERALSLQRKM KAAGIDSTIT EIMTDNGKVY


 


301
RVKSSNYKNA RDAERDLNKL RVHGIAGQVT NE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 746 shows 89.9% identity over a 346 aa overlap with a predicted ORF (ORF 746) from N. gonorrhoeae: 

m746/g746 89.9% identity in 346 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2555>:










a746.seq




1
ATGTCCGAAA ACAAACAAAA CGAAGTCCTG AGCGGTTACG AACAACTCAA


 


51
ACGGCGCAAC CGCCGCCGCC TCGTAACGGC AAGTTGCCTG GTTGCCGCCT


 


101
CCTGCATCCT GCTGGCAGCC GCCCTCAGTT CCGGCCCTGC CGAACAGACT


 


151
GCCGGCGAAA CAAGCGGCGT AGAAAACAAA GCGGCAGGTG CGGCACAAAC


 


201
CCCTGCCTTG AAATCCGCCG CCGACAAACC GCAGGACTTG GCAGGCGAAG


 


251
ACAAGCCTTC TGCCGCCGAC AGCGAAATCA GCGAGCCTGA AAACGTAGGC


 


301
GCGCCGCTGG TGCTGATTAA CGACCGCCTC GAAGACAGCA ACATCAAAGG


 


351
TTTGGAAGCA TCCGAGAAAC TGCAACAGGC AGAAACCGCC AAAACCGCAC


 


401
CGAAGCAGGC AAAACAACGC GCTGCCGAAA AAGTGCCGGC AACTGCCGAC


 


451
AGTACGGATA CGGTAGCGGT TGAAAAACCG AAACGCACTG CCGAAACAAA


 


501
ACCGCAAAAA GCGGAACGCA CTGCCAAAGC CAAGCCCAAA GCCAAAGAAA


 


551
CCAAAACCGC CGAAAAAGTT GCCGACAAAC CGAAAACTGC CGCCGAAAAA


 


601
ACCAAACCGG ATACGGCAAA ATCCGACAGC GCGGTAAAAG AAGCGAAAAA


 


651
AGCCGACAAG GCTGAAAGCA AAAAAACAGC CGAAAAAGAC CGTTCGGACG


 


701
GCAAAAAACA CGAAACGGCA CAAAAAACCG ACAAAGCGGA CAAGACCAAA


 


751
ACCGCCGAGA AGGAAAAATC CGGTAAAAAA GCCGCCATTC AGGCAGGTTA


 


801
TGCCGAAAAA GAACGCGCCT TAAGCCTCCA GCGCAAAATG AAGGCGGCGG


 


851
GTATCGATTC GACCATCACC GAAATTATGA CCGACAACGG CAAAGTTTAC


 


901
CGCGTCAAAT CAAGCAACTA TAAAAACGCA AGGGATGCCG AACGCGATTT


 


951
GAACAAATTG CGCGTACACG GTATCGCCGG TCAGGTAACG AATGAATAA






This corresponds to the amino acid sequence <SEQ ID 2556; ORF 746.a>:










a746.pep




1
MSENKQNEVL SGYEQLKRRN RRRLVTASCL VAASCILLAA ALSSGPAEQT


 


51
AGETSGVENK AAGAAQTPAL KSAADKPQDL AGEDKPSAAD SEISEPENVG


 


101
APLVLINDRL EDSNIKGLEA SEKLQQAETA KTAPKQAKQR AAEKVPATAD


 


151
STDTVAVEKP KRTAETKPQK AERTAKAKPK AKETKTAEKV ADKPKTAAEK


 


201
TKPDTAKSDS AVKEAKKADK AESKKTAEKD RSDGKKHETA QKTDKADKTK


 


251
TAEKEKSGKK AAIQAGYAEK ERALSLQRKM KAAGIDSTIT EIMTDNGKVY


 


301
RVKSSNYKNA RDAERDLNKL RVHGIAGQVT NE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 746 shows 99.7% identity over a 332 aa overlap with a predicted ORF (ORF 746) from N. meningitidis: 

a746/m746; 99.7% identity in 332 aa overlap





g747.seq not found yet

g747.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2557>:










m747.seq




1
CTGACCCCTT GGGCGGATGC ATATGCAGAT TTGCGCGGCA AAACCAAAGT


 


51
GATGACGACC CAGATGGGTG CTTCCCGCGA TGTCAGCAAA AGCGCCAAAG


 


101
GTTGGAGTGT CGGTATCGGT CTGAATGTAG GCAAACAGTT GACCGACAGC


 


151
GTCGGTCTCG AGTTTGATCC ATACTACCGT CACAAAACAA TCTACAAACC


 


201
CCGTGAGATT GTCTTGGACG GTGACAAAAC CAAAATGGGC CGCTCCAAAT


 


251
CCAACGAGTA CGGCTTCCGC GTAGCCGCAA CGTTCTATAG TCAATTAAAA


 


301
TCAAAATAG






This corresponds to the amino acid sequence <SEQ ID 2558; ORF 747>:










m747.pep




1
LTPWADAYAD LRGKTKVMTT QMGASRDVSK SAKGWSVGIG LNVGKQLTDS


 


51
VGLEFDPYYR HKTIYKPREI VLDGDKTKMG RSKSNEYGFR VAATFYSQLK


 


101
SK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2559>:










a747.seq




1
CTAACCCCTT GGGCGGATGC ATATGCAGAT TTGCGCGGCA AAACCAAAGT


 


51
GATGACGACC CAGATGTGTG CTTCCCGCGA TGTCAGCAAA AGCGCCAAAG


 


101
GTTGGAGTGT CGGTATCGGT CTGAATGTAG GCAAACAGTT GACCGACAGC


 


151
GTCGGTCTCG AGTTTGATCC ATACTACCGT CACAAAACAA TCTGCAAACC


 


201
CCGTGAGATT GTTTTGGACG GCGACAAAAC CAAAATGGGC CGCTCCAAAT


 


251
CCAACGAGTA CGGCTTCCGC GTAACCGCAA CGTTCTATAG TCAATTAAAA


 


301
TCAAAGTAG






This corresponds to the amino acid sequence <SEQ ID 2560; ORF 747.a>:










a747.pep




1
LTPWADAYAD LRGKTKVMTT QMCASRDVSK SAKGWSVGIG LNVGKQLTDS


 


51
VGLEFDPYYR HKTICKPREI VLDGDKTKMG RSKSNEYGFR VTATFYSQLK


 


101
SK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 747 shows 97.1% identity over a 102 aa overlap with a predicted ORF (ORF 746) from N. meningitidis: 

a747/m747 97.1% identity in 102 aa overlap





a747/m80195









gi|150271 (M80195) outer membrane protein [Neisseria meningitidis]



Length = 272 Score = 59.3 bits (141), Expect = 6e−09


Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 4/99 (4%)











Query:
1
LTPWADAYADLRGKTKVMTTQMCASRDVSKSAKGWSVGIGLNVGKQLTDSVGLEFDPYYR
60





+ PW++   DL  + K+ T      +D+++   GW  G+G N+GK+L +S  +E  P+Y+


Sbjct:
174
INPWSEVKFDLNSRYKLNTGVTNLKKDINQKTNGWGFGLGANIGKKLGESASIEAGPFYK
233


 


Query:
61
HKTICKPREIVL---DGD-KTKMGRSKSNEYGFRVTATF
95




 +T  +  E  +    GD    + ++   EYG RV   F


Sbjct:
234
QRTYKESGEFSVTTKSGDVSLTIPKTSIREYGLRVGIKF
272






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2561>:










g748.seq




1
ATGAGTCAAA ACCAACCCGC ACAACCGACC AAACGCAATC TGTTCAAAAC


 


51
CGCCCTTGCC GTCGGCGCAA TCGGCGCAAT CGGAGGTTAT TTCGGCGGCA


 


101
AAAAACAGGG CGAAACCGCC GAACGCACCG CCGAAAGCCA ACACTCGCCC


 


151
CAAGCCTATC CCTGCTACGG CGAACATCAG GCAGGTATCG TTACGCCGCG


 


201
GCAGGCGTTT TCCATTATGT GCGCCTTCGA CGTAACCGCG CAAAGTGCCA


 


251
AGCAGCTGGA AAACCTGTTC CGCACACTGA CCGCCCGCAT CGAGTTTCTC


 


301
ACCCAAGGCG GAGAATACCA AGACGGCGAC GACAAACTCC CGTCAGCCGG


 


351
CAGCGGCATT TTGGGTAAAG CCTTCAACCC CGACGGATTG ACCGTTACCG


 


401
TGGGGGTGGG CAGCAGCCTG TTTGACGGCC GGTTCGGACT CAAAGACAAA


 


451
AAAACGGTTC ATTTGCAGGA AATGCGCGAC TTCCCCAACG ATAAGCTGCA


 


501
AAAAAGCTGG TGCGACGGCG ATTTGAGCCT GCAAATCTGC GCCTTCACCC


 


551
CCGAAACCTG CCAAACCGCC CTGCGCGACA TCATCAAACA CACCGCCCAA


 


601
ACCGCCGTCA TCCGCTGGAG TATCGACGGG TGGCAGCCTA AATCCGAACC


 


651
CGGCGCGATG GCGGCGCGCA ACCTGTTGGG CTTCCGAGAC GGCACGGGCA


 


701
ACCCCAAGGT TTCCGATCCC AAAACCGCCG ACGAGGTTTT ATGGACGGGC


 


751
GTGGCCGCCA ACAGCCTCGA CGAACCGGAG TGGGCGAAAA ACGGCAGCTA


 


801
TCAGGCAGTC CGCCTTATCC GCCGCTTTGT CGAGTTTTGG GACAGGACGC


 


851
CGCTTCAAGA GCAAACCGAC ATTTTCGGGC GGCGAAAATA CAGCGGGGCG


 


901
CCGATGGACG GCAAAAAAGA AGCCGACCAA CCGGATTTCG CCAAAGACCC


 


951
CGAGGGTGAT ATCACGCCCA AAGACAGCCA TATGCGCCTG GCGAATCCGC


 


1001
GCGATCCCGA ATTCCTCAAA AAACACTGCC TCTTCCGCCG CGCCTACAGC


 


1051
TATTCTCGCG GACCCGCCTC AAGCGGACAG CTTGATGTCG GGCTGGTGTT


 


1101
CGTCTGCTAT CAGGCAAATC TTGCCGACGG TTTCATCTTC GTGCAAAACC


 


1151
TCCTCAACGG CGAACCGCTG GAAGAATACA TCAGCCCCTT CGGCGGCGGC


 


1201
TATTTCTTCG TCTTGCCCGG CGTGGGAAAA GGCGGATTCT TGGGACAAGG


 


1251
GCTGCCGGGC GTATAA






This corresponds to the amino acid sequence <SEQ ID 2562; ORF 748.ng>:










g748.pep




1
MSQNQPAQPT KRNLFKTALA VGAIGAIGGY FGGKKQGETA ERTAESQHSP


 


51
QAYPCYGEHQ AGIVTPRQAF SIMCAFDVTA QSAKQLENLF RTLTARIEFL


 


101
TQGGEYQDGD DKLPSAGSGI LGKAFNPDGL TVTVGVGSSL FDGRFGLKDK


 


151
KTVHLQEMRD FPNDKLQKSW CDGDLSLQIC AFTPETCQTA LRDIIKHTAQ


 


201
TAVIRWSIDG WQPKSEPGAM AARNLLGFRD GTGNPKVSDP KTADEVLWTG


 


251
VAANSLDEPE WAKNGSYQAV RLIRRFVEFW DRTPLQEQTD IFGRRKYSGA


 


301
PMDGKKEADQ PDFAKDPEGD ITPKDSHMRL ANPRDPEFLK KHCLFRRAYS


 


351
YSRGPASSGQ LDVGLVFVCY QANLADGFIF VQNLLNGEPL EEYISPFGGG


 


401
YFFVLPGVGK GGFLGQGLPG V*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2563>:










m748.seq




1
ATGAGCAAAA AACAACCCGC ACAACCGACC AGGCGCACTC TTTTTAAAAC


 


51
CGCGATCGCA GCCGGAGCAG TCGGCGCAAT CGGAGGTTAT CTCGGCGGCA


 


101
AAAAACAGGG CGAAACCGCC GAACGCACCG CCGAAAGCCA ACACTCGCCC


 


151
CAAGCCTATC CCTGCTACGG CGAACATCAG GCAGGCATCG TTACGCCGCA


 


201
GCAGGCGTTT TCGATTATGT GCGCCTTCGA CGTAACCGCG CAAAGTGCCA


 


251
AGCAGCTGGA AAACCTGTTC CGCACGCTGA CCGCCCGCAT CGAGTTTCTC


 


301
ACCCAAGGCG GCGAATACCA AGACGGCGAC GACAAACTTC CGCCAGCCGG


 


351
CAGCGGCATT TTGGGCAAAG CCTTCAACCC CGACGGGTTG ACCGTTACCG


 


401
TGGGGGTGGG CAGCAGCCTG TTTGACGGCC GGTTCGGACT CAAAGACAAA


 


451
AAACCGATTC ATTTGCAGGA AATGCGCGAC TTCTCCAACG ATAAGCTGCA


 


501
AAAAAGCTGG TGCGACGGCG ATTTGAGCCT GCAAATCTGT GCCTTCACCC


 


551
CCGAAACCTG CCAAGCCGCC CTGCGCGACA TCATCAAACA CACCGTCCAA


 


601
ACCGCCGTTA TCCGTTGGAG TATCGACGGG TGGCAGCCCA AATCCGAACC


 


651
CGGCGCGATG GCGGCGCGCA ACCTGTTGGG CTTCAGGGAC GGCACGGGCA


 


701
ACCCCAAAGT TTCCGATCCC AAAACTGCCG ACGAGGTTTT GTGGACGGGG


 


751
GTGGCCGCCA ACAGCCTCGA CGAACCGGAG TGGGCGAAAA ACGGCAGCTA


 


801
TCAGGCAGTC CGCCTTATCC GCCACTTTGT CGAGTTTTGG GACAGGACGC


 


851
CGCTTCAAGA GCAAACCGAC ATTTTCGGGC GGCGCAAATA CAGCGGTGCG


 


901
CCGATGGACG GCAAAAAAGA AGCCGACCAA CCGGATTTTG CCAAAGACCC


 


951
CGAGGGTGAT ATCACGCCCA AAGACAGCCA TATACGCCTG GCGAATCCGC


 


1001
GCGATCCCGA ATTCCTCAAA AAACACCGCC TCTTCCGCCG CGCCTACAGC


 


1051
TATTCGCGCG GACTCGCCTC AAGCGGACAG CTTGATGTCG GGCTGGTGTT


 


1101
CGTCTGCTAT CAGGCAAACC TTGCCGACGG ATTCATCTTC GTGCAAAACC


 


1151
TCCTCAACGG CGAACCGCTG GAAGAATACA TCAGCCCCTT CGGCGGCGGC


 


1201
TATTTCTTCG TCTTGCCCGG CGTGGAAAAA GGCGGCTTTT TGGGGCAAGG


 


1251
GCTGCTGGGC GTATAA






This corresponds to the amino acid sequence <SEQ ID 2564; ORF 748>:










m748.pep




1
MSKKQPAQPT RRTLFKTAIA AGAVGAIGGY LGGKKQGETA ERTAESQHSP


 


51
QAYPCYGEHQ AGIVTPQQAF SIMCAFDVTA QSAKQLENLF RTLTARIEFL


 


101
TQGGEYQDGD DKLPPAGSGI LGKAFNPDGL TVTVGVGSSL FDGRFGLKDK


 


151
KPIHLQEMRD FSNDKLQKSW CDGDLSLQIC AFTPETCQAA LRDIIKHTVQ


 


201
TAVIRWSIDG WQPKSEPGAM AARNLLGFRD GTGNPKVSDP KTADEVLWTG


 


251
VAANSLDEPE WAKNGSYQAV RLIRHFVEFW DRTPLQEQTD IFGRRKYSGA


 


301
PMDGKKEADQ PDFAKDPEGD ITPKDSHIRL ANPRDPEFLK KHRLFRRAYS


 


351
YSRGLASSGQ LDVGLVFVCY QANLADGFIF VQNLLNGEPL EEYISPFGGG


 


401
YFFVLPGVEK GGFLGQGLLG V*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 748 shows 95.0% identity over a 421 aa overlap with a predicted ORF (ORF 748) from N. gonorrhoeae 

m748/g748 95.0% identity in 421 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2565>:










a748.seq




1
ATGAGCAAAA ACCAACCCGC ACAACCGACC AGGCGCACTC TTTTTAAAAC


 


51
CGCGATCGCA GCTGGAGCAG TCGGCGCAAT CGGAGGTTAT CTCGGCGGCA


 


101
AAAAACGGGG CGAAACCGCC GAACGCACCG CCGAAAGCCA ACACTCGCCC


 


151
CAAGCCTATC CCTGCTACGG CGAACATCAG GCAGGCATCG TTACGCCGCA


 


201
GCAGGCGTTT TCGATTATGT GCGCCTTCGA CGTAACCGCG CAAAGTGCCA


 


251
AGCAGCTGGA AAACCTGTTC CGCACGCTGA CCGCCCGCAT CGAGTTTCTC


 


301
ACCCAAGGCG GCGAATACCA AGACGGCGAC GACAAACTTC CGCCAGCCGG


 


351
CAGCGGCATT TTGGGCAAAG CCTTCAACCC CGACGGGTTG ACCGTTACCG


 


401
TGGGGGTGGG CAGCAGCCTG TTTGACGGCC GGTTCGGACT CAAAGACAAA


 


451
AAACCGATTC ATTTGCAGGA AATGCGCGAC TTCTCCAACG ATAAGCTGCA


 


501
AAAAAGCTGG TGCGACGGCG ATTTGAGCCT GCAAATCTGT GCCTTCACCC


 


551
CCGAAACCTG CCAAGCCGCC CTGCGCGACA TCATCAAACA CACCGTCCAA


 


601
ACCGCCGTTA TCCGCTGGAG TATCGACGGG TGGCAGCCTA AATCCGAACC


 


651
CGGCGCGATG GCGGCGCGCA ACCTGTTGGG CTTCCGCGAC GGCACGGGCA


 


701
ACCCCAAAGT TTCCGACCCC AAAACTGCCG ACGAGGTTTT GTGGACGGGG


 


751
GTGGCCGCCA ACAGCCTCGA CGAACCGGAG TGGGCGAAAA ACGGCAGCTA


 


801
TCAGGCAGTC CGCCTTATCC GCCACTTTGT TGAGTTTTGG GACAGGACGC


 


851
CGCTTCAAGA GCAAACCGAC ATTTTCGGGC GGCGCAAATA CAGCGGCGCG


 


901
CCGATGGACG GCAAAAAAGA AGCCGACCAA CCGGATTTTG CCAAAGACCC


 


951
CGAGGGGAAT ACCACGCCCA AAGACAGCCA TATACGCCTG GCGAATCCGC


 


1001
GCGATCCCGA GTTCCTTAAA AAACACCGCC TCTTCCGCCG CGCCTACAGC


 


1051
TATTCGCGCG GACTCGCCTC AAGCGGACAG CTTGATGTCG GGCTGGTGTT


 


1101
CGTCTGCTAT CAGGCAAACC TTGCCGACGG ATTCATCTTC GTGCAAAACC


 


1151
TCCTCAACGG CGAACCGCTG GAAGAATACA TCAGCCCCTT CGGCGGCGGC


 


1201
TATTTCTTCG TCTTGCCCGG CGTGGAAAAA GGCGGCTTTT TGGGGCAAGG


 


1251
GCTGCTGGGC GTATAA






This corresponds to the amino acid sequence <SEQ ID 2566; ORF 748.a>:










a748.pep




1
MSKNQPAQPT RRTLFKTAIA AGAVGAIGGY LGGKKRGETA ERTAESQHSP


 


51
QAYPCYGEHQ AGIVTPQQAF SIMCAFDVTA QSAKQLENLF RTLTARIEFL


 


101
TQGGEYQDGD DKLPPAGSGI LGKAFNPDGL TVTVGVGSSL FDGRFGLKDK


 


151
KPIHLQEMRD FSNDKLQKSW CDGDLSLQIC AFTPETCQAA LRDIIKHTVQ


 


201
TAVIRWSIDG WQPKSEPGAM AARNLLGFRD GTGNPKVSDP KTADEVLWTG


 


251
VAANSLDEPE WAKNGSYQAV RLIRHFVEFW DRTPLQEQTD IFGRRKYSGA


 


301
PMDGKKEADQ PDFAKDPEGN TTPKDSHIRL ANPRDPEFLK KHRLFRRAYS


 


351
YSRGLASSGQ LDVGLVFVCY QANLADGFIF VQNLLNGEPL EEYISPFGGG


 


401
YFFVLPGVEK GGFLGQGLLG V*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 748 shows 99.0% identity over a 421 aa overlap with a predicted ORF (ORF 748) from N. meningitidis: 

a748/m748 99.0% identity in 421 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2567>:










g749.seq




1
ATGAGAAAAT TCAATTTGAC CGCATTGTCC GTGATGCTTG CCTTGGGTTT


 


51
GACCGCGTGC CAGCCGCCGG AGGCGGAGAA AGCCGCGCCG GCCGCGTCCG


 


101
GTGAGACCCA ATCCGCCAAC GAAGGCGGTT CGGTCGGTAT CGCCGTCAAC


 


151
GACAATGCCT GCGAACCGAT GAATCTGACC GTGCCGAGCG GACAGGTTGT


 


201
GTTCAATATT AAAAACAACA GCGGCCGCAA GCTCGAATGG GAAATCCTGA


 


251
AGGGCGTGAT GGTGGTGGAC GAACGCGAAA ATATCGCCCC GGGGCTTTCC


 


301
GACAAAATGA CCGTAAccct GCTGCCGGGC GAATACGAAA TGACCTGCGG


 


351
CCTTTTGACC AATCCGCGCG GCAAGCTGGT GGTAGCCGAC AGCGGCTTTA


 


401
AAGACACCGC CAACGAAGCG GATTTGGAAA AACTGCCCCA ACCGCTCGCC


 


451
GACTATAAAG CCTACGTTCA AGGCGAGGTT AAAGAGCTGG CGGCGAAAAC


 


501
CAAAACCTTT ACCGAAGCCG TCAAAGCAGG CGACATTGAA AAGGCGAAAT


 


551
CCCTGTTTGC CGCCACCCGC GTCCATTACG AACGCATCGA ACCGATTGCC


 


601
GAGCTTTTCA GCGAACTCGA CCCCGTCATC GATGCGTGTG AAGACGACTT


 


651
CAAAGACGGT GCGAAAGATG CCGGGTTTAC CGGCTTCCAC CGTATCGAAC


 


701
ACGCCCTTTG GGTGGAAAAA GACGTATCCG GCGTGAAGGA AACCGCGGCC


 


751
AAACTGATGA CCGATGTCGA AGCCCTGCAA AAAGAAATCG ACGCATTGGC


 


801
GttccctCCG GGCAAAGTGG TCGGCGGCGC GTCCGAACTG ATTGAAGAAG


 


851
CGGCGGGCAG TAAAATCAGC GGCGAAGAAG ACCgttaCAG CCACACCGAT


 


901
TTGAGCGACT TCCAAGCTAA TGCGGACGGA TCTAAAAAAA TCGTCGATTT


 


951
GTTCCGTCCG TTGATTGAGG CCAAAAACAA AGCCTTGTTG GAAAAAACCG


 


1001
ATACCAACTT CAAACAGGTC AACGAAATTC TGGCGAAATA CCGCACCAAA


 


1051
GACGGTTTTG AAACCTACGA CAAGCTGAGC GAAGCCGACC GCAAAGCATT


 


1101
ACAGGCTCCT ATTAACGCGC TTGCCGAAGA CCTTGCCCAA CTTCGCGGCA


 


1151
TACTCGGCTT GAAATAA






This corresponds to the amino acid sequence <SEQ ID 2568; ORF 749.ng>:










g749.pep




1
MRKFNLTALS VMLALGLTAC QPPEAEKAAP AASGETQSAN EGGSVGIAVN


 


51
DNACEPMNLT VPSGQVVFNI KNNSGRKLEW EILKGVMVVD ERENIAPGLS


 


101
DKMTVTLLPG EYEMTCGLLT NPRGKLVVAD SGFKDTANEA DLEKLPQPLA


 


151
DYKAYVQGEV KELAAKTKTF TEAVKAGDIE KAKSLFAATR VHYERIEPIA


 


201
ELFSELDPVI DACEDDFKDG AKDAGFTGFH RIEHALWVEK DVSGVKETAA


 


251
KLMTDVEALQ KEIDALAFPP GKVVGGASEL IEEAAGSKIS GEEDRYSHTD


 


301
LSDFQANADG SKKIVDLFRP LIEAKNKALL EKTDTNFKQV NEILAKYRTK


 


351
DGFETYDKLS EADRKALQAP INALAEDLAQ LRGILGLK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2569>:










m749.seq




1
ATGAGAAAAT TCAATTTGAC CGCATTGTCC GTGATGCTTG CCTTAGGTTT


 


51
GACCGCGTGC CAGCCGCCGG AGGCGGAGAA AGCTGCGCCG GCAGCGTCCG


 


101
GTGAGGCGCA AACCGCCAAC GAGGGCGGTT CGGTCAGTAT CGCCGTCAAC


 


151
GACAATGCCT GCGAACCGAT GGAACTGACC GTGCCGAGCG GACAGGTTGT


 


201
GTTCAATATT AAAAACAACA GCGGCCGCAA GCTCGAATGG GAAATCCTGA


 


251
AAGGCGTGAT GGTGGTGGAC GAGCGCGAAA ACATCGCCCC CGGACTTTCC


 


301
GATAAAATGA CCGTCACCCT GTTGCCGGGC GAATACGAAA TGACTTGCGG


 


351
TCTTTTGACC AATCCGCGCG GCAAGCTGGT GGTAACCGAC AGCGGCTTTA


 


401
AAGACACCGC CAACGAAGCG GATTTGGAAA AACTGTCCCA ACCGCTCGCC


 


451
GACTATAAAG CCTACGTTCA AGGCGAGGTT AAAGAGCTGG TGGCGAAAAC


 


501
CAAAACTTTT ACCGAAGCCG TCAAAGCAGG CGACATTGAA AAGGCGAAAT


 


551
CCCTGTTTGC CGACACCCGC GTCCATTACG AACGCATCGA ACCGATTGCC


 


601
GAGCTTTTCA GCGAACTCGA CCCCGTCATC GATGCGCGTG AAGACGACTT


 


651
CAAAGACGGC GCGAAAGATG CCGGATTTAC CGGCTTTCAC CGTATCGAAT


 


701
ACGCCCTTTG GGTGGAAAAA GACGTGTCCG GCGTGAAGGA AATTGCAGCG


 


751
AAACTGATGA CCGATGTCGA AGCCCTGCAA AAAGAAATCG ACGCATTGGC


 


801
GTTTCCTCCG GGCAAGGTGG TCGGCGGCGC GTCCGAACTG ATTGAAGAAG


 


851
TGGCGGGCAG TAAAATCAGC GGCGAAGAAG ACCGGTACAG CCACACCGAT


 


901
TTGAGCGACT TCCAAGCCAA TGTGGACGGA TCTAAAAAAA TCGTCGATTT


 


951
GTTCCGTCCG CTGATCGAGG CCAAAAACAA AGCCTTGTTG GAAAAAACCG


 


1001
ATACCAACTT CAAACAGGTC AACGAAATTC TGGCGAAATA CCGGACTAAA


 


1051
GACGGTTTTG AAACCTACGA CAAGCTGGGC GAAGCCGACC GCAAAGCGTT


 


1101
ACAGGCCTCT ATTAACGCGC TTGCCGAAGA CCTTGCCCAA CTTCGCGGCA


 


1151
TACTCGGCTT GAAATAA






This corresponds to the amino acid sequence <SEQ ID 2570; ORF 749>:










m749.pep




1
MRKFNLTALS VMLALGLTAC QPPEAEKAAP AASGEAQTAN EGGSVSIAVN


 


51
DNACEPMELT VPSGQVVFNI KNNSGRKLEW EILKGVMVVD ERENIAPGLS


 


101
DKMTVTLLPG EYEMTCGLLT NPRGKLVVTD SGFKDTANEA DLEKLSQPLA


 


151
DYKAYVQGEV KELVAKTKTF TEAVKAGDIE KAKSLFADTR VHYERIEPIA


 


201
ELFSELDPVI DAREDDFKDG AKDAGFTGFH RIEYALWVEK DVSGVKEIAA


 


251
KLMTDVEALQ KEIDALAFPP GKVVGGASEL IEEVAGSKIS GEEDRYSHTD


 


301
LSDFQANVDG SKKIVDLFRP LIEAKNKALL EKTDTNFKQV NEILAKYRTK


 


351
DGFETYDKLG EADRKALQAS INALAEDLAQ LRGILGLK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 749 shows 96.1% identity over a 388 aa overlap with a predicted ORF (ORF 749) from N. gonorrhoeae 

m749/g749 96.1% identity in 388 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2571>:










a749.seq




1
ATGAGAAAAT TCAATTTGAC CGCATTGTCC GTGATGCTTG CCTTAGGTTT


 


51
GACCGCGTGC CAGCCGCCGG AGGCGGAGAA AGCTGCGCCG GCAGCGTCCG


 


101
GTGAGGCGCA AACCGCCAAC GAGGGCGGTT CGGTCAGTAT CGCCGTCAAC


 


151
GACAATGCCT GCGAACCGAT GGAACTGACC GTGCCGAGCG GACAGGTTGT


 


201
GTTCAATATT AAAAACAACA GCGGCCGCAA GCTCGAATGG GAAATCCTGA


 


251
AAGGCGTGAT GGTGGTGGAC GAGCGCGAAA ACATCGCCCC CGGACTTTCC


 


301
GATAAAATGA CCGTCACCCT GTTGCCGGGC GAATACGAAA TGACTTGCGG


 


351
TCTTTTGACC AATCCGCGCG GCAAGCTGGT GGTAACCGAC AGCGGCTTTA


 


401
AAGACACCGC CAACGAAGCG GATTTGGAAA AACTGTCCCA ACCGCTCGCC


 


451
GACTATAAAG CCTATGTTCA AGGCGAAGTC AAAGAGCTGG TGGCGAAAAC


 


501
CAAAACCTTT ACCGAAGCCG TCAAAGCAGG CGACATTGAA AAGGCGAAAT


 


551
CCCTGTTTGC CGACACCCGC GTCCATTACG AACGCATCGA ACCGATTGCC


 


601
GAGCTTTTCA GCGAACTCGA CCCCGTCATC GATGCGCGTG AAGACGACTT


 


651
CAAAGACGGC GCGAAAGATG CCGGATTTAC CGGCTTCCAC CGTATCGAAT


 


701
ACGCCCTTTG GGTGGAAAAA GACGTGTCCG GCGTGAAGGA AATTGCAGCG


 


751
AAACTGATGA CCGATGTCGA AGCCCTGCAA AAAGAAATCG ACGCATTGGC


 


801
GTTTCCTCCG GGCAAGGTGG TCGGCGGCGC GTCCGAACTG ATTGAAGAAG


 


851
TGGCGGGCAG TAAAATCAGC GGCGAAGAAG ACCGGTACAG CCACACCGAT


 


901
TTGAGCGACT TCCAAGCCAA TGTGGACGGA TCGAAAAAAA TCGTCGATTT


 


951
GTTCCGTCCG TTGATCGAGA CCAAAAACAA AGCCTTGTTG GAAAAAACCG


 


1001
ATACCAACTT CAAACAGGTC AACGAAATTC TGGCGAAATA CCGGACTAAA


 


1051
GACGGTTTTG AAACCTACGA CAAGCTGGGC GAAGCCGACC GCAAAGCGTT


 


1101
ACAGGCCTCT ATTAACGCGC TTGCCGAAGA CCTTGCCCAA CTTCGCGGCA


 


1151
TACTCGGCTT GAAATAA






This corresponds to the amino acid sequence <SEQ ID 2572; ORF 749.a>:










a749.pep




1
MRKFNLTALS VMLALGLTAC QPPEAEKAAP AASGEAQTAN EGGSVSIAVN


 


51
DNACEPMELT VPSGQVVFNI KNNSGRKLEW EILKGVMVVD ERENIAPGLS


 


101
DKMTVTLLPG EYEMTCGLLT NPRGKLVVTD SGFKDTANEA DLEKLSQPLA


 


151
DYKAYVQGEV KELVAKTKTF TEAVKAGDIE KAKSLFADTR VHYERIEPIA


 


201
ELFSELDPVI DAREDDFKDG AKDAGFTGFH RIEYALWVEK DVSGVKEIAA


 


251
KLMTDVEALQ KEIDALAFPP GKVVGGASEL IEEVAGSKIS GEEDRYSHTD


 


301
LSDFQANVDG SKKIVDLFRP LIETKNKALL EKTDTNFKQV NEILAKYRTK


 


351
DGFETYDKLG EADRKALQAS INALAEDLAQ LRGILGLK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 749 shows 99.7% identity over a 388 aa overlap with a predicted ORF (ORF 749) from N. meningitidis: 

a749/m749 99.7% identity in 388 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2573>:










g750.seq




1
GTGAAACCGC GTTTTTATTG GGCAGcctGC GCCGTCCTGC CGGCCGCCTG


 


51
TTCGCCCGAA CCTGCCGCCG AAAAAACTGT ATccgCCGCA TCCCAAGCCG


 


101
CATCCACACC TGTCGCCACG CTGACCGTGC CGACCGCGCG GGGCGATGCC


 


151
GTTGTGCCGA AGAATCCCGA ACgcgtcgcc gtgtAcgaCt ggGCGGCGTt


 


201
ggaTACGCTG ACCGAGCCGG GCGTGAATGT GGGCGCAACC ACCGCGCCGG


 


251
TGCGCGTGGA CTATTTGCAG CCTGCATTTG ACAAGGCGGC AACGGTGGGG


 


301
ACGCTGTTTG AGCCCGATTG CGAATCCCTG CACCGCCACA ATCCGCAGTT


 


351
TGTCATTACC GGCGGGCCGG GTGCGGAAGC GTATGAACAG TTGGCGAAAA


 


401
ACGCGACCAC CATAGATTTG ACGGTGGACA ACGGCAATAT CCGCACCAGC


 


451
GGCGAGAAGC AGATGGAGAC CCTGTCGCGG ATTTTCGGTA AGGAAGCGCG


 


501
CGTGGCGGAA TTGAATGCGC AGATTGACGC GCTGTTCGCC CAAAAGCGCG


 


551
AAGCCGCCAA AGGCAAAGGA CGCGGGCTGG TGCTGTCGGT TACAGGCAAC


 


601
AAGGTGTCCG CCTTCGGCAC GCAATCGCGG TTGGCAAGTT GGATACACGG


 


651
CGACATCGGC CTGCCGCCCG TGGACGAATC TTTACGCAAC GAAGGGCACG


 


701
GGCAGCCCGT TTCCTTCGAA TACATCAAAG AGAAAAACCC CGGCTGGATT


 


751
TTCATCATCG ACCGCACCGC CGCCATCGGG CAGGAAGGGC CGGCTGCCGT


 


801
GGAAGTGTTG GATAACGCGC TGGTATGCGG CACGAACGCT TGGAAGCGCA


 


851
AGCAAATCAT CGTCATGCCT GCCGCGAACT ACATTGTCGC GGGCGGCGCG


 


901
CGGCAGTTGA TACAGGCGGC GGAACAGTTG AAGGCGGCGT TTGAAAAGGC


 


951
AGAACCCGTT GCGGCGCAGT AG






This corresponds to the amino acid sequence <SEQ ID 2574; ORF 750.ng>:










g750.pep




1
VKPRFYWAAC AVLPAACSPE PAAEKTVSAA SQAASTPVAT LTVPTARGDA


 


51
VVPKNPERVA VYDWAALDTL TEPGVNVGAT TAPVRVDYLQ PAFDKAATVG


 


101
TLFEPDCESL HRHNPQFVIT GGPGAEAYEQ LAKNATTIDL TVDNGNIRTS


 


151
GEKQMETLSR IFGKEARVAE LNAQIDALFA QKREAAKGKG RGLVLSVTGN


 


201
KVSAFGTQSR LASWIHGDIG LPPVDESLRN EGHGQPVSFE YIKEKNPGWI


 


251
FIIDRTAAIG QEGPAAVEVL DNALVCGTNA WKRKQIIVMP AANYIVAGGA


 


301
RQLIQAAEQL KAAFEKAEPV AAQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2575>:










m750.seq




1
GTGAAACCGC GTTTTTATTG GGCAGCCTGC GCCGTCCTGC TGACCGCCTG


 


51
TTCGCCCGAA CCTGCCGCCG AAAAAACTGT ATCCGCCGCA TCCGCATCTG


 


101
CCGCCACGCT GACCGTGCCG ACCGCGCGGG GCGATGCCGT TGTGCCGAAG


 


151
AATCCCGAAC GCGTCGCCGT GTACGACTGG GCGGCGTTGG ATACGCTGAC


 


201
CGAATTGGGC GTGAATGTGG GCGCAACCAC CGCGCCGGTG CGCGTGGATT


 


251
ATTTGCAGCC TGCATTTGAC AAGGCGGCAA CGGTGGGGAC GCTGTTCGAG


 


301
CCCGATTACG AAGCCCTGCA CCGCTACAAT CCTCAGCTTG TCATTACCGG


 


351
CGGGCCGGGC GCGGAAGCGT ATGAACAGTT AGCGAAAAAC GCGACCACCA


 


401
TAGATCTGAC GGTGGACAAC GGCAATATCC GCACCAGCGG CGAAAAGCAG


 


451
ATGGAGACCT TGGCGCGGAT TTTCGGCAAG GAAGCGCGCG CGGCGGAATT


 


501
GAAGGCGCAG ATTGACGCGC TGTTCGCCCA AACGCGCGAA GCCGCCAAAG


 


551
GCAAAGGACG CGGGCTGGTG CTGTCGGTTA CGGGCAACAA GGTGTCCGCC


 


601
TTCGGCACGC AGTCGCGGTT GGCAAGTTGG ATACACGGCG ACATCGGCCT


 


651
ACCGCCTGTA GACGAATCTT TACGCAACGA GGGGCACGGG CAGCCTGTTT


 


701
CCTTCGAATA CATCAAAGAG AAAAACCCCG ATTGGATTTT CATCATCGAC


 


751
CGTACCGCCG CCATCGGGCA GGAAGGGCCG GCGGCTGTCG AAGTATTGGA


 


801
TAACGCGCTG GTACGCGGCA CGAACGCTTG GAAGCGCAAG CAAATCATCG


 


851
TCATGCCTGC CGCGAACTAC ATTGTCGCGG GCGGCGCGCG GCAGTTGATT


 


901
CAGGCGGCGG AGCAGTTGAA GGCGGCGTTT AAAAAGGCAG AACCCGTTGC


 


951
GGCGGGGAAA AAGTAG






This corresponds to the amino acid sequence <SEQ ID 2576; ORF 750>:










m750.pep




1
VKPRFYWAAC AVLLTACSPE PAAEKTVSAA SASAATLTVP TARGDAVVPK


 


51
NPERVAVYDW AALDTLTELG VNVGATTAPV RVDYLQPAFD KAATVGTLFE


 


101
PDYEALHRYN PQLVITGGPG AEAYEQLAKN ATTIDLTVDN GNIRTSGEKQ


 


151
METLARIFGK EARAAELKAQ IDALFAQTRE AAKGKGRGLV LSVTGNKVSA


 


201
FGTQSRLASW IHGDIGLPPV DESLRNEGHG QPVSFEYIKE KNPDWIFIID


 


251
RTAAIGQEGP AAVEVLDNAL VRGTNAWKRK QIIVMPAANY IVAGGARQLI


 


301
QAAEQLKAAF KKAEPVAAGK K*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 750 shows 93.8% identity over a 322 aa overlap with a predicted ORF (ORF 750) from N. gonorrhoeae 

m750/g750 93.8% identity in 322 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2577>:










a750.seq




1
GTGAAACCGC GTTTTTATTG GGCAGCCTGC GCCGTCCTGC TGACCGCCTG


 


51
TTCGCCCGAA CCTGCCGCCG AAAAAACTGT ATCCGCCGCA TCCGCATCTG


 


101
CCGCCACACT GACCGTGCCG ACCGCGCGGG GCGATGCCGT TGTGCCGAAG


 


151
AATCCCGAAC GCGTCGCCGT GTACGACTGG GCGGCGTTGG ATACGCTGAC


 


201
CGAATTGGGT GTGAATGTGG GCGCAACCAC CGCGCCGGTG CGCGTGGATT


 


251
ATTTGCAGCC TGCATTTGAC AAGGCGGCAA CGGTGGGGAC GCTGTTCGAG


 


301
CCCGATTACG AAGCCCTGCA CCGCTACAAT CCTCAGCTTG TCATTACCGG


 


351
CGGGCCGGGC GCGGAAGCGT ATGAACAGTT GGCGAAAAAC GCGACCACCA


 


401
TAGATCTGAC GGTGGACAAC GGCAATATCC GCACCAGCGG CGAAAAGCAG


 


451
ATGGAGACCT TGGCGCGGAT TTTCGGCAAG GAAGCGCGCG CGGCGGAATT


 


501
GAAGGCGCAG ATTGACGCGC TGTTCGCCCA AACGCGCGAA GCCGCCAAAG


 


551
GCAAAGGACG CGGGCTGGTG CTGTCGGTTA CGGGCAACAA GGTGTCCGCC


 


601
TTCGGCACGC AGTCGCGGTT GGCAAGTTGG ATACACGGCG ACATCGGCCT


 


651
ACCGCCTGTA GACGAATCTT TACGCAACGA GGGGCACGGG CAGCCTGTTT


 


701
CCTTCGAATA CATCAAAGAG AAAAACCCCG ATTGGATTTT CATCATCGAC


 


751
CGTACCGCCG CCATCGGGCA GGAAGGGCCG GCGGCTGTCG AAGTATTGGA


 


801
TAACGCGCTG GTACGCGGCA CGAACGCTTG GAAGCGCAAG CAAATCATCG


 


851
TCATGCCTGC CGCGAACTAC ATTGTCGCGG GCGGCTCGCG GCAGTTGATT


 


901
CAGGCGGCGG AGCAGTTGAA GGAGGCGTTT GAAAAGGCAG AACCCGTTGC


 


951
GGCGGGGAAA GAGTAG






This corresponds to the amino acid sequence <SEQ ID 2578; ORF 750.a>:










a750.pep




1
VKPRFYWAAC AVLLTACSPE PAAEKTVSAA SASAATLTVP TARGDAVVPK


 


51
NPERVAVYDW AALDTLTELG VNVGATTAPV RVDYLQPAFD KAATVGTLFE


 


101
PDYEALHRYN PQLVITGGPG AEAYEQLAKN ATTIDLTVDN GNIRTSGEKQ


 


151
METLARIFGK EARAAELKAQ IDALFAQTRE AAKGKGRGLV LSVTGNKVSA


 


201
FGTQSRLASW IHGDIGLPPV DESLRNEGHG QPVSFEYIKE KNPDWIFIID


 


251
RTAAIGQEGP AAVEVLDNAL VRGTNAWKRK QIIVMPAANY IVAGGSRQLI


 


301
QAAEQLKEAF EKAEPVAAGK E*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 750 shows 98.8% identity over a 321 aa overlap with a predicted ORF (ORF 750) from N. meningitidis: 

a750/m750 98.8% identity in 321 aa overlap





g751.seq not found yet

g751.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2579>:










m751.seq..




1
ATGGCTTGGA GTATGTTTGC CACAACCCAA GCCGATAGAG CGGTAAGGTC


 


51
TGCAACTGCA CCTAAAGAAA TGTGGTTCCA TAAGAAGATA ATAGATGAAA


 


101
AAACAGGTAA AGTATCCTTT GATACCAGAC AAATTTGGTC ATTGAATGAT


 


151
TTAAGCAAGG AAGAACTGGC AAGCATTCAA GACACAAATG GCAAAGTTAT


 


201
TACTGTGTCT AATCCTGGTA TTTTCAATAA TCGAGAAGAT TCATTAAGCA


 


251
ACGCAGCAAA ACAAAATCGT AATAGTACAA ACGGTAGTGG TGTTATTGCA


 


301
GTCATGAATC CTCCAACAGG GAAATATAAA TCTGATTCTA ATAACAAAAT


 


351
AAAAGATTTT TTATGGCTCG GTTCAAGTCT TGTTTCTGAA CTGATGTATG


 


401
TCGGTTACGA CCAATTAAAT AATAAAGTGT TCCAAGGCTA TTTACCCAAA


 


451
ACCAATTCAG AAAAACTGAA TCAAGATATT TATCGAGAGG TTCAAAAAAT


 


501
GGGTAACGGC TGGTCGGTTG ATACCAGTAA TCACAGTCGT GGGGGAATTA


 


551
CAGCAAGCGT TTCCTTAAAA GATTGGGTAA ACAATCAAAA ACAAAATGGC


 


601
ATTGCCCCAA TCAGAAAAGC ACGTTTCTAT GGTACAGCCA CAAATGTGCA


 


651
GAATGATTAC GCCGATGTTT TACAGAAAAA CGGCTATACC TATACGGGTG


 


701
CAGACGGCAA AACTTATAAC AGCGGATCCT ACTCAATCGT GCATGATAAA


 


751
GATTTTGTGG GGAACAAATG GATACCTTTC TTGCTAGGAA CCAATGACAC


 


801
CACACAAGGT ACATGTAAGG GGTTGTGCTA TTCGCATAGC AGTTATTTTG


 


851
CGGAGGTGCC AAAAGCAGGT ACAAAAGAAT TTGATGACTA TGTAAAAATA


 


901
TGGGGTGAAG TTGAATATGA CGCTCAAGGT AAGCCAATTA ACAAATCTAA


 


951
ACCCATACTG GTAGAACCAA ACAAAACAAA AGATAATGAA AAATATGAAA


 


1001
AAGAAGCTTT CTAA






This corresponds to the amino acid sequence <SEQ ID 2580; ORF 751>:










m751.pep..




1
MAWSMFATTQ ADRAVRSATA PKEMWFHKKI IDEKTGKVSF DTRQIWSLND


 


51
LSKEELASIQ DTNGKVITVS NPGIFNNRED SLSNAAKQNR NSTNGSGVIA


 


101
VMNPPTGKYK SDSNNKIKDF LWLGSSLVSE LMYVGYDQLN NKVFQGYLPK


 


151
TNSEKLNQDI YREVQKMGNG WSVDTSNHSR GGITASVSLK DWVNNQKQNG


 


201
IAPIRKARFY GTATNVQNDY ADVLQKNGYT YTGADGKTYN SGSYSIVHDK


 


251
DFVGNKWIPF LLGTNDTTQG TCKGLCYSHS SYFAEVPKAG TKEFDDYVKI


 


301
WGEVEYDAQG KPINKSKPIL VEPNKTKDNE KYEKEAF*






a751.seq not found yet

a751.pep not found yet

g752.seq not found yet
g752.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2581>:









m752.seq..




1
ATGAAAATTT CCAGACCTCC GGAATTTACC CTGTTGCAAC AGGAATATAT


 


51
GCAGCATCTC ACTGAAAGAA TGACGCAAAT TGCCAAGCTG CTGAATTCTT


 


101
CCGCAAACAA TCCTGATATA GACATTCCCG ATTTTCTTAC TGAAATCAAA


 


151
GATTATTCAG AATTTTCCGT GACAGATGAA AATGGAACCT ACCTGCATTG


 


201
GGACAAATTC CGCCGGATTC ACACGGAAGA TACGCGGATG AAATGGCGCG


 


251
CCGTTAAGGA AAGCCGCAAA AAAATCCAAA AACCAATTGA TTTCCCGTTT


 


301
GAACATCAGT TTTGGTTCTG CATTCCCGAC TCTTTGCAGG CACGGCTTCA


 


351
TTTGATTGAC AAAAGCTGCG GCAGTTCTAT CGGCACGTCT AGCTTGGGTG


 


401
GCTTCGGCAG AAGCGAGCAA AACAGATTCT TGCTCAAGTC TCTGATTATG


 


451
GAAGAAGCGA TTACATCCGC CCAACTGGAA GGTGCGGCTA CCACGCGTAA


 


501
AGTGGCCAAG GATATGCTCA AATCGCAGCG TAAACCCAAA ACAAAAGACG


 


551
AAATCATGAT AGTGAACAAC TATCACTTGA TGAAAAAAGC GGTAGAATTG


 


601
AAAAATACGC CGTTAAGTGT TGAAATGATT TTGGATTTGC ACCGCATTGC


 


651
TACCAGTAAC GCTATTGAAA ACAAGGCCGA GCCCGGACAA TTCAGGCAGG


 


701
ATGACGAAAT CTTTATCGCC GATATCAATG GTAACAGCCT GTATCAACCA


 


751
CCGCCGCACG GACAGGTTCA TACGCTGATG GAAGAGGTGT GTGCGTTTGC


 


801
CAATAATACC TATGACGGCG TGGAAAATCC GTTTATCCAT CCGGTTGTCC


 


851
AAGCTATTAT CTTGCATTTC CTCATCGGCT ACATCCACCC ATTTGGTGAT


 


901
GGCAACGGGC GGACAGCGCG GGCTTTGTTC TATTGGTTTA TGCTCAAAAA


 


951
CGGCTACTGG CTATTTGAAT ACATATCCAT CAGCCGTCTT CTGAAAAACG


 


1001
CTCCTGCCCA ATACGCCAAA TCCTATTTGT ATGCGGAAAC TGACGATTTA


 


1051
GATTTAACCT ATTTCATCTA TTACCAATGC GATATTATCA AGCGGGCGGT


 


1101
TGCCGATTTG GAGCACTACA TTTCCGACAA ACAAAAACAC CAACAGGAAT


 


1151
TCAAAGCAGC GATTGCCCAA TATACTGAAA AGATAGGAAA GTTGAACCAA


 


1201
CGGCAAATTG GTATCCTGCA AAAAGCAGTG GAAGAAAGCG GAAAAATCTT


 


1251
TACTGCACAA GAAATTGCCA ACCAATACGG CATCTCCCTG AATACTGCCC


 


1301
GTAGCGATTT GAGTAAACTG GGAGAATATA GATTCCTAGT GCCGTTCAAA


 


1351
TCAGGAAATG CTTTAGAGTA TGTTGCTCCT CAGGATTTAT TGGAAAGGTT


 


1401
AGAAAAAAAA TAG






This corresponds to the amino acid sequence <SEQ ID 2582; ORF 752>:










m752.pep




1
MKISRPPEFT LLQQEYMQHL TERMTQIAKL LNSSANNPDI DIPDFLTEIK


 


51
DYSEFSVTDE NGTYLHWDKF RRIHTEDTRM KWRAVKESRK KIQKPIDFPF


 


101
EHQFWFCIPD SLQARLHLID KSCGSSIGTS SLGGFGRSEQ NRFLLKSLIM


 


151
EEAITSAQLE GAATTRKVAK DMLKSQRKPK TKDEIMIVNN YHLMKKAVEL


 


201
KNTPLSVEMI LDLHRIATSN AIENKAEPGQ FRQDDEIFIA DINGNSLYQP


 


251
PPHGQVHTLM EEVCAFANNT YDGVENPFIH PVVQAIILHF LIGYIHPFGD


 


301
GNGRTARALF YWFMLKNGYW LFEYISISRL LKNAPAQYAK SYLYAETDDL


 


351
DLTYFIYYQC DIIKRAVADL EHYISDKQKH QQEFKAAIAQ YTEKIGKLNQ


 


401
RQIGILQKAV EESGKIFTAQ EIANQYGISL NTARSDLSKL GEYRFLVPFK


 


451
SGNALEYVAP QDLLERLEKK *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2583>:










m752-1.seq




1
ATGAAAATTT CCAGACCTCC GGAATTTACC CTGTTGCAAC AGGAATATAT


 


51
GCAGCATCTC ACTGAAAGAA TGACGCAAAT TGCCAAGCTG CTGAATTCTT


 


101
CCGCAAACAA TCCTGATATA GACATTCCCG ATTTTCTTAC TGAAATCAAA


 


151
GATTATTCAG AATTTTCCGT GACAGATGAA AATGGAACCT ACCTGCATTG


 


201
GGACAAATTC CGCCGGATTC ACACGGAAGA TACGCGGATG AAATGGCGCG


 


251
CCGTTAAGGA AAGCCGCAAA AAAATCCAAA AACCAATTGA TTTCCCGTTT


 


301
GAACATCAGT TTTGGTTCTG CATTCCCGAC TCTTTGCAGG CACGGCTTCA


 


351
TTTGATTGAC AAAAGCTGCG GCAGTTCTAT CGGCACGTCT AGCTTGGGTG


 


401
GCTTCGGCAG AAGCGAGCAA AACAGATTCT TGCTCAAGTC TCTGATTATG


 


451
GAAGAAGCGA TTACATCCGC CCAACTGGAA GGTGCGGCTA CCACGCGTAA


 


501
AGTGGCCAAG GATATGCTCA AATCGCAGCG TAAACCCAAA ACAAAAGACG


 


551
AAATCATGAT AGTGAACAAC TATCACTTGA TGAAAAAAGC GGTAGAATTG


 


601
AAAAATACGC CGTTAAGTGT TGAAATGATT TTGGATTTGC ACCGCATTGC


 


651
TACCAGTAAC GCTATTGAAA ACAAGGCCGA GCCCGGACAA TTCAGGCAGG


 


701
ATGACGAAAT CTTTATCGCC GATATCAATG GTAACAGCCT GTATCAACCA


 


751
CCGCCGCACG GACAGGTTCA TACGCTGATG GAAGAGGTGT GTGCGTTTGC


 


801
CAATAATACC TATGACGGCG TGGAAAATCC GTTTATCCAT CCGGTTGTCC


 


851
AAGCTATTAT CTTGCATTTC CTCATCGGCT ACATCCACCC ATTTGGTGAT


 


901
GGCAACGGGC GGACAGCGCG GGCTTTGTTC TATTGGTTTA TGCTCAAAAA


 


951
CGGCTACTGG CTATTTGAAT ACATATCCAT CAGCCGTCTT CTGAAAAACG


 


1001
CTCCTGCCCA ATACGCCAAA TCCTATTTGT ATGCGGAAAC TGACGATTTA


 


1051
GATTTAACCT ATTTCATCTA TTACCAATGC GATATTATCA AGCGGGCGGT


 


1101
TGCCGATTTG GAGCACTACA TTTCCGACAA ACAAAAACAC CAACAGGAAT


 


1151
TCAAAGCAGC GATTGCCCAA TATACTGAAA AGATAGGAAA GTTGAACCAA


 


1201
CGGCAAATTG GTATCCTGCA AAAAGCAGTG GAAGAAAGCG GAAAAATCTT


 


1251
TACTGCACAA GAAATTGCCA ACCAATACGG CATCTCCCTG AATACTGCCC


 


1301
GTAGCGATTT GAGTAAACTG GGAGAATATA GATTCCTAGT GCCGTTCAAA


 


1351
TCAGGAAATG CTTTAGAGTA TGTTGCTCCT CAGGATTTAT TGGAAAGGTT


 


1401
AGAAAAAAAA TAG






This corresponds to the amino acid sequence <SEQ ID 2584; ORF 752-1>:










m752-1.pep




1
MKISRPPEFT LLQQEYMQHL TERMTQIAKL LNSSANNPDI DIPDFLTEIK


 


51
DYSEFSVTDE NGTYLHWDKF RRIHTEDTRM KWRAVKESRK KIQKPIDFPF


 


101
EHQFWFCIPD SLQARLHLID KSCGSSIGTS SLGGFGRSEQ NRFLLKSLIM


 


151
EEAITSAQLE GAATTRKVAK DMLKSQRKPK TKDEIMIVNN YHLMKKAVEL


 


201
KNTPLSVEMI LDLHRIATSN AIENKAEPGQ FRQDDEIFIA DINGNSLYQP


 


251
PPHGQVHTLM EEVCAFANNT YDGVENPFIH PVVQAIILHF LIGYIHPFGD


 


301
GNGRTARALF YWFMLKNGYW LFEYISISRL LKNAPAQYAK SYLYAETDDL


 


351
DLTYFIYYQC DIIKRAVADL EHYISDKQKH QQEFKAAIAQ YTEKIGKLNQ


 


401
RQIGILQKAV EESGKIFTAQ EIANQYGISL NTARSDLSKL GEYRFLVPFK


 


451
SGNALEYVAP QDLLERLEKK *






a752.seq not found yet

a752.pep not found yet

g753.seq not found yet
g753.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2585>:









m753.seq




1
ATGCCCATCA CTCCACCCTT AAACATCATC TCTCCTAAAC TCTACCCCAA


 


51
TGAACAATGG AACGAAAGCG AAGCACTCGG TGCCATCACT TGGCTATGGT


 


101
ATCAGTCGCC TACGCATCGC CAAGTACCTA TTGTGGAGAT GATGACGTAT


 


151
ATATTGCCTG TGTTAAAAAA CGGGCAGTTC GCTTTGTTTT GCAAGGGTAC


 


201
CCAACCAATC GGTTATATCT CATGGGCTTA TTTTGATGAA GTGGCGCAGG


 


251
CGCATTATTT AGAATCTGAC CGCCATTTGC GTGACAACAG CGATTGGAAC


 


301
TGTGGCGACA ATATTTGGCT GATTCAATGG TTTGCGCCAT TGGGACACAG


 


351
TCATCAAATG CGCTCAGCTG TGCGCCAGTT ATTTCCTAGT ACGACAGTAC


 


401
GCGCCTTGTA TCATAAAGGG AGCGATAAGG GTTTGAGAAT TTTAACTTTT


 


451
AAAACTTGA






This corresponds to the amino acid sequence <SEQ ID 2586; ORF 753>:










m753.pep




1
MPITPPLNII SPKLYPNEQW NESEALGAIT WLWYQSPTHR QVPIVEMMTY


 


51
ILPVLKNGQF ALFCKGTQPI GYISWAYFDE VAQAHYLESD RHLRDNSDWN


 


101
CGDNIWLIQW FAPLGHSHQM RSAVRQLFPS TTVRALYHKG SDKGLRILTF


 


151
KT*






a753.seq not found yet
a753.pep not found yet
g754.seq not found yet
g754.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2587>:









m754.seq




1
ATGATGAAGT CTATCCTCAC CGTATCCGGA AATCGTATGC GTAAACCCAG


 


51
AATCACCTAT TTGGATGTTT GGGCAAACGA TGAAAGAATC GGTACTTTGG


 


101
AAAAGGGGGC CATGTATCGG TTCGCATACG ACAATCCCAA TTCTTCGTTG


 


151
CTGGGCCTGC ATTATCAAGA CAGAAGCAAG GTATATATCA GCAACAATAT


 


201
GCCGCATATC TTTGCACAGT ATTTTCCGGA AGGCTTTTTG GATGCACACA


 


251
TCACAAGCAA ATATGCTTTT CATGATGCGC CTTTTGAAGA CAATGAGATG


 


301
CTGCGCTTGG CAATTCTGTG CAGAGAGACT TTGGGTCGGA TACATGTGCG


 


351
CTGTAATGAC CCGCTTTTTA ATGAATGGAT TGACGGGTTG GAGATGAAAA


 


401
ATCCAAGAAT ATTGACTGAA CGGGATTTGC TGGGCATAAA TGCCCGACAG


 


451
GTTTTTCAGC AATATATGGC AGAAATCTTC CATCACGGCC GTTTCGTCAG


 


501
TGTATCCGGG ATACAGCAGA AGATGTCCTT AGATGCCATC CGCAGAAATA


 


551
CCAAGCAAAC TGCCTCATAT ATTGCCAAAG GTTTTGATGC ATCCGAATAT


 


601
CCTTGCTTGG CTGCCAATGA ATTTTTATGC ATGCAGACCA TCAAACAAGC


 


651
CGGCATTGCC GTTGCACAGA CCAGCCTGTC GGAAGATTCA TCAGTCTTAT


 


701
TGGTACGTCG GTTTGATGTC AGTGAACAGG GTTATTTTTT AGGGATGGAA


 


751
GACTTTACCA GTCTGCGCCA GTATTCGGTA GAAGATAAAT ATAAAGGCAG


 


801
TTATGCGGCT ATTGCACAGA TTATCCGACA GATATCCGGC AGACCAGATG


 


851
AAGATTTAAT CCATTTCTTT AATCAGCTTG CTGCCAGTTG CATATTGAAA


 


901
AACGGCGATG CACACCTCAA AAATTTTTCA GTACTCTATC ATGACGAATA


 


951
CGATGTTCGT CTTGCACCTG TCTATGATGT ATTGGATACA TCAATATACA


 


1001
GGGTTGGAAC ACAAGGAATT TTTGATGCTT ATGACGATAC GCTGGCATTA


 


1051
AACCTGACTA ACCACGGTAA GAAAACATAT CCTTCCAAGA ATACATTGTT


 


1101
GGATTTTGCT GAGAAATATT GCGATTTGGG AAGAGAAGAT GCATCCTTTA


 


1151
TGATAGATAC AATCGTTCAA GCTAAAGAAC AGGTTCTTGT TAAATACTCG


 


1201
GATGTATTGC GTGAGAATGA ATGGTTGGCG CAGAAGTGGC ATTTTATCCC


 


1251
GGATGAAAAT GAAGAAGGTC TACCGTTTAC ATTCCGGTAG






This corresponds to the amino acid sequence <SEQ ID 2588; ORF 754>:










m754.pep




1
MMKSILTVSG NRMRKPRITY LDVWANDERI GTLEKGAMYR FAYDNPNSSL


 


51
LGLHYQDRSK VYISNNMPHI FAQYFPEGFL DAHITSKYAF HDAPFEDNEM


 


101
LRLAILCRET LGRIHVRCND PLFNEWIDGL EMKNPRILTE RDLLGINARQ


 


151
VFQQYMAEIF HHGRFVSVSG IQQKMSLDAI RRNTKQTASY IAKGFDASEY


 


201
PCLAANEFLC MQTIKQAGIA VAQTSLSEDS SVLLVRRFDV SEQGYFLGME


 


251
DFTSLRQYSV EDKYKGSYAA IAQIIRQISG RPDEDLIHFF NQLAASCILK


 


301
NGDAHLKNFS VLYHDEYDVR LAPVYDVLDT SIYRVGTQGI FDAYDDTLAL


 


351
NLTNHGKKTY PSKNTLLDFA EKYCDLGRED ASFMIDTIVQ AKEQVLVKYS


 


401
DVLRENEWLA QKWHFIPDEN EEGLPFTFR*






a754.seq not found yet
a754.pep not found yet
g755.seq not found yet
g755.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2589>:









m755.seq..




1
ATGAGCCGTT ACCTGATTAC CTTTGATATG GATACCAACT GCCTGAAAGA


 


51
CAATTACCAC GGAAATAACT ATACCAATGC CTACTCCGAT ATTAAAACCA


 


101
TCTTGGCTAG ACATGGATTT GAGAACATTC AGGGCAGTGT TTATCTAGGC


 


151
CGTGAAGGCA TCAGTGAAGC ACACGGAACA ATAGCCATTC AGGAACTGAC


 


201
CGCTCGGTTT GATTGGTTTT ACTCCTGTAT TTCAAACATT AAGTTTTACC


 


251
GCCTTGAAAG TGATTTGAAC GCACAATTTA TCGCTGATGG TGTGTATCAA


 


301
GCCAAACAGG CTTTCCTTCA ACGTGTTGAA CAACTTCGTA TATCCCTAAC


 


351
AGAAGCTGGA TTGTCTGATG AGCAAATCAA TCAGGTTCTG GAAAAACAGA


 


401
AATTTGAATT GGAAAGTCCT AACCTGAAAT TAAATTAA






This corresponds to the amino acid sequence <SEQ ID 2590; ORF 755>:










m755.pep..




1
MSRYLITFDM DTNCLKDNYH GNNYTNAYSD IKTILARHGF ENIQGSVYLG


 


51
REGISEAHGT IAIQELTARF DWFYSCISNI KFYRLESDLN AQFIADGVYQ


 


101
AKQAFLQRVE QLRISLTEAG LSDEQINQVL EKQKFELESP NLKLN*






a755.seq not found yet
a755.pep not found yet
g756.seq not found yet
g756.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2591>:









m756.seq




1
ATGACCGCCA ACTTTGCACA GACGCTGGTC GAAATACAGG ACAGTCTGTA


 


51
CAGGGTTGTG TCAACCGTCC AATACGGGGA TGACAACCTC AAGCGGTTGA


 


101
CAGCGGACAA ACGGAAGCAG TATGAGTTGA ACTTCAAGAT TTCCGAGGGT


 


151
TCTACGCGTG TAGAGTCCGA CTTTAAAGAG ACTTTGGTTC GGTTCGGTAG


 


201
AGATATGCTT CAAGATATGC CCCCTAAAAT CCGTTCGGCA ACGCTGGTAG


 


251
CGTTGACGAC CCTGCTTGTC GGAGGGGCGT TGGGTTACGG TTATTTGGAA


 


301
TACCTGAAGC AGGTTGCTTC GGAAGGGTAT CAGACCGAGC GTCTGTATAA


 


351
TGCCGTCGAC CGTCTTGCAG AATCCCAAGA ACGGATAACG TCCGCCATCC


 


401
TGAAGGGTGC TAGAGGTGCC GATTTCGTGC AAATCGGCAG ACGTTCCTAC


 


451
AGTAGGGAGG ATATATCGGA GGCAAATAGA CGTGCAGAGC GTGTCCCGTA


 


501
TGGCGCAGAG TTGGTTTCAG ACGGCAATTT TACCGCTGTT TTATCTGATA


 


551
TAGGGGATTA A






This corresponds to the amino acid sequence <SEQ ID 2592; ORF 756>:










m756.pep




1
MTANFAQTLV EIQDSLYRVV STVQYGDDNL KRLTADKRKQ YELNFKISEG


 


51
STRVESDFKE TLVRFGRDML QDMPPKIRSA TLVALTTLLV GGALGYGYLE


 


101
YLKQVASEGY QTERLYNAVD RLAESQERIT SAILKGARGA DFVQIGRRSY


 


151
SREDISEANR RAERVPYGAE LVSDGNFTAV LSDIGD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2593>:










a756.seq




1
ATGACCGCCA ACTTTGCACA GACGCTGGTC GAAATACAGG ACAGTCTGTA


 


51
NAGGGTTGTG TCAACCGTCC AATACGGGGA TGACAACCTC AAGCGGTTGA


 


101
CAGCGGACAA ACGGAAGCAG TATGAGTTGA ACTTCAAGAT TTCCGAGGGT


 


151
TCTACGCGTG TAGAGTCCGA CTTTAAAGAG ACTTTGGTTC GGTTCGGTAG


 


201
AGATATGCTT CAAGATATGC CCCCTAAAAT CCGTTCGGCA ACGCTGGTAG


 


251
CGTTGACGAC CCTGCTTGTC GGAGGGGCGT TGGGTTACGG TTATTTGGAA


 


301
TACCTGAAGC AGGTTGCTTC GGAAGGGTAT CAGACCGAGC GTCTGTATAA


 


351
TGCCGTCGAC CGTCTTGCAG AATCCCAAGA ACGGATAACG TCCGCCATCC


 


401
TGAAGGGTGC TAGAGGTGCC GATTTCGTGC AAATCGGCAG ACGTTCCTAC


 


451
AGTAGGGAGG ATATATCGGA GGCAAATAGA CGTGCAGAGC GTGTCCCGTA


 


501
TGGCGCAGAG TTGGTTTCAG ACGGCAATTT TACCGCTGTT TTATCTGATA


 


551
TAGGGGATTA A






This corresponds to the amino acid sequence <SEQ ID 2594; ORF 756.a>:










a756.pep




1
MTANFAQTLV EIQDSLXRVV STVQYGDDNL KRLTADKRKQ YELNFKISEG


 


51
STRVESDFKE TLVRFGRDML QDMPPKIRSA TLVALTTLLV GGALGYGYLE


 


101
YLKQVASEGY QTERLYNAVD RLAESQERIT SAILKGARGA DFVQIGRRSY


 


151
SREDISEANR RAERVPYGAE LVSDGNFTAV LSDIGD*






m756/a756 99.5% identity in 186 aa overlap





g757.seq not found yet

g757.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2595>:










m757.seq




1
ATGAAAATAC TCGCTTTATT AATTGCCGCT ACCTGTGCTT TATCTGCGTG


 


51
TGGCAGCCAA TCTGAAGAAC AACCGGCATC TGCACAACCC CAAGAGCAGG


 


101
CACAATCCGA ATTAAAAACC ATGCCGGTAA GCTATACCGA CTATCAATCA


 


151
GCAGCCAATA AAGGGCTGAA TGACCAAAAA ACCGGTCTGA CCCTTCCTGA


 


201
ACATGTTGTC CCTATCGACA ATGCGGAAGG AAAGAATCTG CTGCATGACT


 


251
TTTCAGACGG CCTCACAATC TTAACCGTTG ATACCGATAA AGCCGACAAA


 


301
ATTACTGCTG TCCGAGTAGT CTGGAATACA GATGCAATGC CTCAAAAAGC


 


351
GGAAAAACTG TCCAAAGCTG CCGCAGCCTT GATTGCGGCA ACCGCTCCGG


 


401
AAGACCGCAC AATGCTGCGT GATACCGGCG ACCAAATCGA AATGGCGATT


 


451
GACAGCCATA ATGCGCAAAA AGAGCCAACC CGAGAATGGG CGCGTGGTGG


 


501
GATTGCTTAT AAAGTCACTG TTACCAATTT ACCGAGCGTG GTTTTGACGG


 


551
CAAAAGCTGA GTAA






This corresponds to the amino acid sequence <SEQ ID 2596; ORF 757>:









m757.pep (lipoprotein)










1
MKILALLIAA TCALSACGSQ SEEQPASAQP QEQAQSELKT MPVSYTDYQS



 


51
AANKGLNDQK TGLTLPEHVV PIDNAEGKNL LHDFSDGLTI LTVDTDKADK


 


101
ITAVRVVWNT DAMPQKAEKL SKAAAALIAA TAPEDRTMLR DTGDQIEMAI


 


151
DSHNAQKEPT REWARGGIAY KVTVTNLPSV VLTAKAE*






a757.seq not found yet
a757.pep not found yet
g758.seq not found yet
g758.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2597>:









m758.seq




1
ATGAACAATC TGACCGTGTT TACCCGTTTC GATACCGATT TGGCGACGCT


 


51
TGCCGATGAA TTGCAATATG TGTGGGAACA CACCGCCGTT ACAGACCATC


 


101
AGGGCAAACT GGTGGAAATT CCCGTCTGCT ACGGCGGCGA ATACGGCCCG


 


151
GATTTGGCGG AAGTCGCTGC TTTCCATCAG ACGGTTATTT CCGAAATCGT


 


201
CCGCCGCCAT ACGGCGCAAA CTTATACCGT ATTTATGATG GGCTTCCAGC


 


251
CCGGTTTCCC TTATCTGGGC GGCTTGCCCG AAGCATTGCA CACGCCCCGC


 


301
CGTGCCGTGC CGAGAACGTC CGTTCCTGCC GGTTCGGTCG GTATCGGCGG


 


351
CAGTCAGACC GGTGTGTATC CGTTCGCTTC GCCCGGCGGC TGGCAGATTA


 


401
TCGGCAGAAC CGAATTACCC TTGTTCCGAG CCGATTTGAA TCCGCCGACC


 


451
CTGCTGGCGG CGGGTGACCA AGTCCGCTTT GTTGCAGAAA GGATTGAGCC


 


501
ATGA






This corresponds to the amino acid sequence <SEQ ID 2598; ORF 758>:










m758.pep




1
MNNLTVFTRF DTDLATLADE LQYVWEHTAV TDHQGKLVEI PVCYGGEYGP


 


51
DLAEVAAFHQ TVISEIVRRH TAQTYTVFMM GFQPGFPYLG GLPEALHTPR


 


101
RAVPRTSVPA GSVGIGGSQT GVYPFASPGG WQIIGRTELP LFRADLNPPT


 


151
LLAAGDQVRF VAERIEP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2599>:










a758.seq




1
ATGAACAATC TGACCGTGTT CACCCGTTTC GATACCGATT TGGCGACGCT


 


51
TGCCGATGAA TTGCAATATG TGTGGGAACA CACCGCCGTT ACAGACCATC


 


101
AGGGCAAACT GGTGGAAATT CCCGTCTGCT ACGGCGGCGA ATACGGCCCG


 


151
GATTTGGCGG AAGTCGCTGC TTTCCATCAG ACGGTTATTT CCGAAATCGT


 


201
CCGCCGCCAT ACGGCGCAAA CTTATACCGT ATTTATGATG GGCTTCCAGC


 


251
CTGGTTTCCC TTATCTGGGC GGCTTGCCCG AAGCATTGCA CACGCCCCGC


 


301
CGTGCCGTGC CGAGAACGTC CGTTCCTGCC GGTTCGGTCG GTATCGGCGG


 


351
CAGTCAGACC GGTGTGTATC CGTTCGCTTC GCCCGGCGGC TGGCAGATTA


 


401
TCGGCAGAAC CGAATTACCC TTGTTCCGAG CCGATTTGAA TCCGCCGACC


 


451
CTGCTGGCGG CGGGTGACCA AGTCCGCTTT GTTGCAGAAA GGATTGAGCC


 


501
ATGA






This corresponds to the amino acid sequence <SEQ ID 2600; ORF 758.a>:










a758.pep..




1
MNNLTVFTRF DTDLATLADE LQYVWEHTAV TDHQGKLVEI PVCYGGEYGP


 


51
DLAEVAAFHQ TVISEIVRRH TAQTYTVFMM GFQPGFPYLG GLPEALHTPR


 


101
RAVPRTSVPA GSVGIGGSQT GVYPFASPGG WQIIGRTELP LFRADLNPPT


 


151
LLAAGDQVRF VAERIEP*






m758/a758 100.0% identity in 167 aa overlap





g759.seq not found yet
g759.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2601>:









m759.seq




1
ATGCGCTTCA CACACACCAC CCCATTTTGT TCCGTATTGT CCACCCTCGG


 


51
TCTTTTTGCC GTTTCCCCTG CTTACTCATC CATTGTCCGC AACGATGTCG


 


101
ATTACCAATA TTTTCGCGAC TTTGCCGAAA ATAAAGGCGC GTTCACCGTA


 


151
GGTGCAAGCA ATATTTCCAT CCAAGACAAG CAAGGCAAAA TATTAGGCAG


 


201
GGTTCTCAAC GGCATCCCCA TGCCCGACTT CCGCGTCAGC AACCGCCAAA


 


251
CCGCCATCGC CACCCTGGTT CACCCCCAAT ACGTCAACAG TGTCAAACAC


 


301
AACGTCGGCT ACGGTTCCAT ACAATTCGGC AACGACACCC AAAATCCAGA


 


351
AGAACAAGCC TATACCTACC GCCTCGTATC ACGCAACCCG CACCCGGACT


 


401
ACGACTACCA CCTTCCCCGC CTCAACAAAC TGGTTACCGA AATCTCACCT


 


451
ACCGCACTCA GCAGCGTACC CTTGCTTGGA AACGGCCAGC CAAAGGCCAA


 


501
TGCCTACCTC GATACCGACC GCTTCCCCTA CTTTGTACGA CTCGGCTCAG


 


551
GCACGCAACA AGTCCGCAAA GCAGACGGCA CGCGTACACG AACCGCCCCG


 


601
GCATACCAAT ACCTGACCGG CGGCACGCCG CTGAAAGTAT TGGGGTTCCA


 


651
AAACCACGGC TTACTCGTCG GCGGCAGCCT GACCGACCAA CCCCTTAACA


 


701
CCTACGCAAT CGCCGGAGAC AGCGGTTCCC CCCTGTTTGC CTTCGACAAG


 


751
CATGAAAACC GCTGGGTGCT TGCGGGCGTA CTCAGCACCT ACGCCGGCTT


 


801
CGATAATTTC TTCAACAAAT ACATCGTCAC GCAACCCGAA TTCATCCGTT


 


851
CCACCATCCG CCAATACGAA ACCCGGCTGG ATGTCGGGCT GACCACCAAC


 


901
GAACTCATAT GGCGCGACAA CGGTAATGGC AACAGCACCC TGCAAGGGCT


 


951
CAACGAACGC ATCACCCTGC CCATTGCAAA CCCTTCGCTT GCCCCACAAA


 


1001
ACGACAGCAG GCACATGCCG TCTGAAGATG CCGGCAAAAC GCTCATCCTA


 


1051
TCCAGCAGGT TCGACAACAA AACACTGATG CTGGCAGACA ATATCAACCA


 


1101
AGGCGCAGGC GCATTGCAGT TCGACAGCAA CTTCACCGTC GTCGGTAAAA


 


1151
ACCACACATG GCAAGGTGCA GGCGTTATCG TAGCCGACGG CAAACGCGTC


 


1201
TTCTGGCAAG TCAGCAACCC CAAAGGCGAC CGGCTCTCCA AACTGGGCGC


 


1251
AGGCACGCTT ATCGCCAACG GACAAGGCAT CAACCAGGGC GACATCAGCA


 


1301
TCGGGGAAGG CACTGTCGTA CTCGCCCAAA AAGCTGCTTC AGACGGCAGC


 


1351
AAACAAGCAT TCAACCAAGT CGGCATCACC AGCGGCAGGG GCACGGCCGT


 


1401
CCTCGCCGAC AGCCAGCAAA TCAAACCCGA AAACCTCTAT TTCGGCTTCA


 


1451
GGGGCGGACG GCTCGACCTC AACGGCAACA ACCTTGCCTT TACCCATATC


 


1501
CGCCATGCGG ACGGCGGCGC GCAAATCGTC AATCACAACC CTGACCAAGC


 


1551
CGCGACACTG ACGCTGACCG GCAACCCCGT CCTCAGTCCC GAGCATGTCG


 


1601
AGTGGGTGCA ATGGGGCAAC CGTCCGCAAG GCAACGCGGC GGTTTACGAA


 


1651
TACATCAACC CGCACCGCAA CCGTCGGACC GACTACTTCA TACTCAAACC


 


1701
CGGCGGCAAC CCGCGCGAAT TTTTCCCGTT AAATATGAAA AACTCAACAA


 


1751
GCTGGCAATT TATCGGCAAC AACAGGCAAC AGGCCGCCGA ACAAGTCGCC


 


1801
CAAGCCGAAA ATGCCCGCCC CGACCTGATT ACCTTCGGCG GATACTTGGG


 


1851
TGAAAACGCG CAAACGGGCA AAGCCGCGCC GAGTTACAGC AAAACCAATG


 


1901
AAGCAGCCAT AGAAAAAACC CGCCATATCG CAAATGCCGC CGTATACGGC


 


1951
CGGCCCGAAT ACCGTTACAA CGGCGCACTC AACCTGCACT ATCGTCCCAA


 


2001
ACGCACCGAC AGCACGCTGT TGCTCAACGG CGGCATGAAC CTTAACGGGG


 


2051
AAGTCTTGAT TGAGGGCGGC AATATGATTG TGTCAGGCAG GCCCGTACCC


 


2101
CATGCCTACG ACCACCAGGC CAAACGCGAA CCCGTTCTTG AAAACGAATG


 


2151
GACCGACGGC AGCTTCAAGG CTGCACGGTT CACCCTGCGA AACCATGCCC


 


2201
GACTGACGGC AGGGCGCAAT ACCGCGCATC TGGACGGCGA CATAACCGCA


 


2251
TACGATCTGT CCGGCATCGA CCTCGGCTTT ACCCAAGGCA AAACACCGGA


 


2301
ATGCTACCGC TCCTACCATA GCGGCAGCAC CCACTGCACA CCCAACGCCG


 


2351
TTTTAAAAGC CGAAAACTAT CGTGCACTAC CTGCAACGCA AGTACGCGGC


 


2401
GACATTACCC TTAACGACCG TTCAGAGCTC CGCCTGGGCA AAGCACACCT


 


2451
GTACGGCAGC ATCCGTGCCG GCAAAGACAC CGCAGTCCGC ATGGAAGCAG


 


2501
ACAGCAACTG GACACTTTCC CAGTCCAGCC ACACCGGCGC ACTGACGCTT


 


2551
GACGGCGCAC AAATTACCCT GAACCCCGAT TTCGCCAATA ATACACACAA


 


2601
CAACCGCTTC AACACACTGA CCGTCAACGG CACACTTGAC GGGTTCGGCA


 


2651
CATTCCGATT CCTGACCGGC ATCGTCCGAA AACAAAATGC CCCCCCCCTC


 


2701
AAACTGGAAG GGGACAGCCG CGGCGCATTC CAAATCCACG TCAAAAACAC


 


2751
CGGACAAGAA CCTCAAACAA CCGAATCGCT TGCACTTGTG AGCCTCAATC


 


2801
CGAAACACAG CCACCAAGCC CGATTCACCC TCCAAAACGG CTATGCCGAT


 


2851
TTGGGTGCCT ACCGCTACAT CCTCCGCAAA AACAACAACG GATACAGCCT


 


2901
GTACAACCCG CTCAAAGAGG CCGAACTTCA AATTGAAGCC ACGCGTGCGG


 


2951
AACATGAGCG CAACCAACAG GCATACAACC AATTACAGGC AACCGACATC


 


3001
AGCAGACAGG TTCAACATGA CTCTGACGCG ACCAGGCAGG CACTACAGGC


 


3051
CTGGCAGAAC AGTCAAACCG AACTTGCCCG CATCGACAGC CAAGTCCAAT


 


3101
ATCTGTCCGC CCAATTGAAA CAGACAGACC CGCTGACCGG CATTCTGACG


 


3151
CGTGCCCAAA ACCTGTGTGC CGCACAAGGA TACAGTGCCG ATATCTGCCG


 


3201
TCAGGTTGCC AAAGCCGCCG ACACGAACGA CCTGACACTC TTCGAAACCG


 


3251
AACTGGATAC GTATATAGAA CGTGTAGAAA TGGCCGAATC CGAACTTGAC


 


3301
AAAGCACGGC AAGGCGGCGA TGCGCAAGCC GTCGAAACAG CCCGGCACGC


 


3351
CTACCTGAAC GCACTCAACC GTCTGTCCCG ACAAATCCAC AGTTTGAAAA


 


3401
CCGGCGTTGC CGGCATCCGT ATGCCGAACC TGGCCGAACT GATCAGCCGG


 


3451
TCGGCCAACA CCGCCGTTTC CGAACAGGCC GCCTACAATA CCGGCCGGCA


 


3501
ACAGGCGGGA CGCCGCATCG ACCGCCACCT TACCGATCCG CAGCAGCAAA


 


3551
ACATCTGGCT GGAAACCGGT ACGCAACAAA CCGACTACCA TAGCGGCACA


 


3601
CACCGTCCCT ACCAACAAAC TACCAACTAT GCACATATCG GCATCCAAAC


 


3651
CGGCATCACC GACCGTCTCA GTGTCGGTAC GATTTTAACC GATGAGCGCA


 


3701
CAAACAACCG TTTTGATGAA GGCGTATCCG CCCGAAACCG CAGCAACGGC


 


3751
GCACATCTGT TCGTCAAAGG GGAAAACGGC GCACTCTTTG CCGCGGCAGA


 


3801
TTTAGGCTAC AGCAACAGCC GTACCCGATT TACCGATTAT GACGGGGCTG


 


3851
CCGTCCGCCG CCACGCATGG GATGCAGGCA TCAACACCGG CATCAAAATC


 


3901
GATACCGGCA TCAACCTCAG ACCCTATGCC GGCATCCGTA TAAACCGCAG


 


3951
CAACGGCAAC CGGTACGTAC TCGACGGCGC AGAGATAAAC AGCCCGGCGC


 


4001
AAATCCAAAC CACATGGCAT GCCGGCATCC GTCTCGATAA AACCGTCGAA


 


4051
CTGGGTCAAG CCAAGCTGAC CCCCGCCTTC AGCAGCGATT ACTACCATAC


 


4101
CCGCCAAAAC AGCGGTTCCG CCCTCAGCGT CAACGACCGT ACCTTACTGC


 


4151
AGCAAGCCGC CCACGGCACA CTGCATACCC TGCAAATCGA CGCCGGATAC


 


4201
AAAGGCTGGA ACGCCAAACT TCATGCCGCT TACGGCAAAG ACAGCAACAC


 


4251
CGCCCGCCAC AAACAGGCAG GAATCAAAAT AGGCTACAAC TGGTAA






This corresponds to the amino acid sequence <SEQ ID 2602; ORF 759>:










m759.pep




1
MRFTHTTPFC SVLSTLGLFA VSPAYSSIVR NDVDYQYFRD FAENKGAFTV


 


51
GASNISIQDK QGKILGRVLN GIPMPDFRVS NRQTAIATLV HPQYVNSVKH


 


101
NVGYGSIQFG NDTQNPEEQA YTYRLVSRNP HPDYDYHLPR LNKLVTEISP


 


151
TALSSVPLLG NGQPKANAYL DTDRFPYFVR LGSGTQQVRK ADGTRTRTAP


 


201
AYQYLTGGTP LKVLGFQNHG LLVGGSLTDQ PLNTYAIAGD SGSPLFAFDK


 


251
HENRWVLAGV LSTYAGFDNF FNKYIVTQPE FIRSTIRQYE TRLDVGLTTN


 


301
ELIWRDNGNG NSTLQGLNER ITLPIANPSL APQNDSRHMP SEDAGKTLIL


 


351
SSRFDNKTLM LADNINQGAG ALQFDSNFTV VGKNHTWQGA GVIVADGKRV


 


401
FWQVSNPKGD RLSKLGAGTL IANGQGINQG DISIGEGTVV LAQKAASDGS


 


451
KQAFNQVGIT SGRGTAVLAD SQQIKPENLY FGFRGGRLDL NGNNLAFTHI


 


501
RHADGGAQIV NHNPDQAATL TLTGNPVLSP EHVEWVQWGN RPQGNAAVYE


 


551
YINPHRNRRT DYFILKPGGN PREFFPLNMK NSTSWQFIGN NRQQAAEQVA


 


601
QAENARPDLI TFGGYLGENA QTGKAAPSYS KTNEAAIEKT RHIANAAVYG


 


651
RPEYRYNGAL NLHYRPKRTD STLLLNGGMN LNGEVLIEGG NMIVSGRPVP


 


701
HAYDHQAKRE PVLENEWTDG SFKAARFTLR NHARLTAGRN TAHLDGDITA


 


751
YDLSGIDLGF TQGKTPECYR SYHSGSTHCT PNAVLKAENY RALPATQVRG


 


801
DITLNDRSEL RLGKAHLYGS IRAGKDTAVR MEADSNWTLS QSSHTGALTL


 


851
DGAQITLNPD FANNTHNNRF NTLTVNGTLD GFGTFRFLTG IVRKQNAPPL


 


901
KLEGDSRGAF QIHVKNTGQE PQTTESLALV SLNPKHSHQA RFTLQNGYAD


 


951
LGAYRYILRK NNNGYSLYNP LKEAELQIEA TRAEHERNQQ AYNQLQATDI


 


1001
SRQVQHDSDA TRQALQAWQN SQTELARIDS QVQYLSAQLK QTDPLTGILT


 


1051
RAQNLCAAQG YSADICRQVA KAADTNDLTL FETELDTYIE RVEMAESELD


 


1101
KARQGGDAQA VETARHAYLN ALNRLSRQIH SLKTGVAGIR MPNLAELISR


 


1151
SANTAVSEQA AYNTGRQQAG RRIDRHLTDP QQQNIWLETG TQQTDYHSGT


 


1201
HRPYQQTTNY AHIGIQTGIT DRLSVGTILT DERTNNRFDE GVSARNRSNG


 


1251
AHLFVKGENG ALFAAADLGY SNSRTRFTDY DGAAVRRHAW DAGINTGIKI


 


1301
DTGINLRPYA GIRINRSNGN RYVLDGAEIN SPAQIQTTWH AGIRLDKTVE


 


1351
LGQAKLTPAF SSDYYHTRQN SGSALSVNDR TLLQQAAHGT LHTLQIDAGY


 


1401
KGWNAKLHAA YGKDSNTARH KQAGIKIGYN W*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2603>:









g760.seq (partial)










1
AACAACCGCA ACACCCGTTA CGCCGCATTG GGCAAACGCG TGATGGAAGG



 


51
CGTTGAGACC GAAATCAGCG GTGCGATTAC ACCGAAATGG CAAATCCATG


 


101
CAGGTTACAG CTATCTGCAC AGCCAAATCA AAACCGCCGC CAATCCACGC


 


151
GACGACGGCA TCTTCCTGCT GGTGCCCAAA CACAGCGCAA ACCTGTGGAC


 


201
GACTTACCAA GTTACGCCCG GGCTGACCGT CGGCGGCGGC GTGAACGCGA


 


251
TGAGCGGCAT TACTTCATCT GCAGGGATGC ATGCAGGCGG TTATGCCACG


 


301
TTCGATGCGA TGGCGGCATA CCGCTTCACG CCCAAGCTGA AGCTGCAAAT


 


351
CAATGCCGAC AACATCTTCA ACCGCCATTA CTACGCCCGC GTCGGCGGCA


 


401
CGAACACCTT TAACATTCCC GGTTCGGAGC GCAGCCTGAC GGCAAACCTG


 


451
CGTTACAGTT TTTAA






This corresponds to the amino acid sequence <SEQ ID 2604; ORF 760.ng>:









g760.pep (partial)










1
NNRNTRYAAL GKRVMEGVET EISGAITPKW QIHAGYSYLH SQIKTAANPR



 


51
DDGIFLLVPK HSANLWTTYQ VTPGLTVGGG VNAMSGITSS AGMHAGGYAT


 


101
FDAMAAYRFT PKLKLQINAD NIFNRHYYAR VGGTNTFNIP GSERSLTANL


 


151
RYSF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2605>:










m760.seq











1
ATGGGACAGT TTATGTCAGT TTTCCGCATC AATATGACCG CCGCCACGGT



 


51
TTTGGCAGCA CTCTCGTCTT CGGTTTTTGC CGCACAAACG GAAGGTTTGG


 


101
AAACCGTCCA TATTAAGGGT CAGCGTTCTT ACAACGCGAT TGCCACCGAG


 


151
AAAAACGGCG ATTACAGCTC GTTTGCCGCC ACCGTCGGTA CAAAAATCCC


 


201
CGCTTCTTTG CGCGAAATTC CGCAATCCGT CAGCATCATT ACCAACCAGC


 


251
AGGTCAAAGA CCGCAATGTT GATACGTTTG ACCAGTTGGC ACGCAAAACG


 


301
CCCGGCCTGC GCGTGTTGAG CAACGACGAC GGACGCTCTT CGGTTTACGC


 


351
GCGCGGTTAC GAATACAGCG AATACAACAT CGACGGCCTG CCCGCGCAGA


 


401
TGCAGAGTAT CAACGGCACG CTGCCCAACC TGTTCGCCTT CGACCGCGTG


 


451
GAAGTGATGC GCGGGCCGAG CGGACTGTTC GACAGCAGCG GCGAGATGGG


 


501
CGGCATCGTG AATCTGGTGC GCAAACGCCC GACCAAAGCG TTCCAAGGTC


 


551
ATGCGGCGGC AGGGTTCGGT ACGCACAAAC AATATAAAGC CGAGGCGGAC


 


601
GTATCGGGCA GCCTCAATTC AGACGGCAGC GTGCGCGGCC GCGTGATGGC


 


651
GCAGACCGTC GGCGCGTCTC CGCGTCCCGC CGAGAAAAAC AACCGGCGCG


 


701
AAACCTTCTA CGCGGCGGCG GATTGGGACA TCAACCCCGA TACGGTTTTG


 


751
GGCGCGGGCT ATCTTTACCA GCAACGCCGC CTCGCGCCGT ACAACGGCCT


 


801
GCCTGCCGAT GCCAATAACA AATTACCGTC CCTGCCGCAA CACGTATTTG


 


851
TCGGCGCGGA TTGGAACAAA TTTAAAATGC ACAGCCACGA CGTGTTCGCC


 


901
GATTTGAAAC ATTACTTCGG CAACGGCGGC TACGGCAAAG TCGGTATGCG


 


951
CTATTCCGAT CGGAAAGCCG ATTCCAATTA TACGTTTGCG GGCAGCAAAC


 


1001
TCAACAATAC CGGACAAGCC GACGTAGCGG GTTTGGGTAC GGACATTAAA


 


1051
CAAAAAGCCT TTGCGGTTGA CGCAAGTTAC AGCCGTCCGT TTGCCTTGGG


 


1101
CAACACCGCC AACGAATTTG TGATTGGTGC AGACTACAAC CGCTTGCGCA


 


1151
GTACTAATGA ACAAGGGCGT TCGACTTTGT CAAAAAGCGT CGCTTTAGAT


 


1201
GGTTTCCGCG CTTTGCCTTA TAACGGCATA CTTCAGAACG CCCGCGCCGG


 


1251
AAACAAAGGT TTCAATCACT CCGTTACCGA AGAAAACCTC GACGAAACCG


 


1301
GTTTGTATGC CAAGACGGTG TTCCGTCCTC TGGAAGGTTT GTCGTTGATT


 


1351
GCAGGCGGAC GTGTAGGACA TCACAAAATC GAGTCGGGCG ACGGCAAAAC


 


1401
CCTGCATAAA GCTTCGAAAA CCAAATTTAC AAGCTACGCC GGCGCGGTTT


 


1451
ACGATATAGA CGGCAGCAAC AGCCTGTACG CTTCCGCCTC CCAACTCTAC


 


1501
ACACCGCAAA CCAGCATCGG CACCGACGGC AAGCTGCTCA AACCGCGCGA


 


1551
AGGCAACCAG TTTGAAATCG GCTACAAAGG CAGCTACATG GACGACCGCC


 


1601
TCAATACCCG GGTTTCGTTC TACCGCATGA AGGATAAAAA CGCCGCCGCA


 


1651
CCGCTGGACT CAAACAACAA AAAAACCCGT TACGCCGCAT TGGGCAAACG


 


1701
CGTGATGGAA GGTGTTGAGA CCGAAATCAG CGGCGCGATG ACACCGAAAT


 


1751
GGCAAATCCA TGCAGGTTAC AGCTACCTGC ACAGCCAAAT CAAAACCGCC


 


1801
TCCAATTCGC GCGACGAAGG CATCTTCCTG CTGATGCCCA AACACAGCGC


 


1851
AAACCTGTGG ACGACTTACC AAGTTACGTC CGGGCTGACC ATCGGCGGCG


 


1901
GCGTGAACGC GATGAGCGGC ATTACTTCAT CTGCAGGGAT ACATGCAGGC


 


1951
GGTTATGCCA CGTTCGATGC GATGGCGGCA TACCGCTTCA CGCCCAAACT


 


2001
GAAGCTGCAA ATCAACGCCG ACAACATCTT CAACCGCCAT TACTACGCCC


 


2051
GCGTCGGCAG CGAGAGCACC TTTAACATTC CCGGTTCGGA GCGCAGCCTG


 


2101
ACGGCAAACC TGCGTTACAG TTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2606; ORF 760>:










m760.pep




1
MGQFMSVFRI NMTAATVLAA LSSSVFAAQT EGLETVHIKG QRSYNAIATE


 


51
KNGDYSSFAA TVGTKIPASL REIPQSVSII TNQQVKDRNV DTFDQLARKT


 


101
PGLRVLSNDD GRSSVYARGY EYSEYNIDGL PAQMQSINGT LPNLFAFDRV


 


151
EVMRGPSGLF DSSGEMGGIV NLVRKRPTKA FQGHAAAGFG THKQYKAEAD


 


201
VSGSLNSDGS VRGRVMAQTV GASPRPAEKN NRRETFYAAA DWDINPDTVL


 


251
GAGYLYQQRR LAPYNGLPAD ANNKLPSLPQ HVFVGADWNK FKMHSHDVFA


 


301
DLKHYFGNGG YGKVGMRYSD RKADSNYTFA GSKLNNTGQA DVAGLGTDIK


 


351
QKAFAVDASY SRPFALGNTA NEFVIGADYN RLRSTNEQGR STLSKSVALD


 


401
GFRALPYNGI LQNARAGNKG FNHSVTEENL DETGLYAKTV FRPLEGLSLI


 


451
AGGRVGHHKI ESGDGKTLHK ASKTKFTSYA GAVYDIDGSN SLYASASQLY


 


501
TPQTSIGTDG KLLKPREGNQ FEIGYKGSYM DDRLNTRVSF YRMKDKNAAA


 


551
PLDSNNKKTR YAALGKRVME GVETEISGAM TPKWQIHAGY SYLHSQIKTA


 


601
SNSRDEGIFL LMPKHSANLW TTYQVTSGLT IGGGVNAMSG ITSSAGIHAG


 


651
GYATFDAMAA YRFTPKLKLQ INADNIFNRH YYARVGSEST FNIPGSERSL


 


701
TANLRYSF*






m760/g760 91.6% identity in 154 aa overlap





g761.seq not found yet
g761.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2607>:









m761.seq




1
ATGAAAATAT CATTTCATTT AGCTTTATTA CCCACGCTGA TTATTGCTTC


 


51
CTTCCCTGTT GCTGCCGCCG ATACGCAGGA CAATGGTGAA CATTACACCG


 


101
CCACTCTGCC CACCGTTTCC GTGGTCGGAC AGTCCGACAC CAGCGTACTC


 


151
AAAGGCTACA TCAACTACGA CGAAGCCGCC GTTACCCGCA ACGGACAGCT


 


201
CATCAAAGAA ACGCCGCAAA CCATCGATAC GCTCAATATC CAGAAAAACA


 


251
AAAATTACGG TACGAACGAT TTGAGTTCCA TCCTCGAAGG CAATGCCGGC


 


301
ATCGACGCTG CCTACGATAT GCGCGGTGAA AGCATTTTCC TGCGCGGTTT


 


351
TCAAGCCGAC GCATCCGATA TTTACCGCGA CGGCGTGCGC GAAAGCGGAC


 


401
AAGTGCGCCG CAGTACTGCC AACATCGAGC GCGTGGAAAT CCTGAAAGGC


 


451
CCGTCTTCCG TGCTTTACGG CCGCACCAAC GGCGGCGGCG TCATCAACAT


 


501
GGTCAGCAAA TACGCCAACT TCAAACAAAG CCGCAACATC GGAGCGGTTT


 


551
ACGGCTCATG GGCAAACCGC AGCCTGAATA TGGACATTAA CGAAGTGCTG


 


601
AACAAAAACG TCGCCATCCG TCTCACCGGC GAAGTCGGGC GCGCCAATTC


 


651
GTTCCGCAGC GGCATAGACA GCAAAAATGT CATGGTTTCG CCCAGCATTA


 


701
CCGTCAAACT CGACAACGGC TTGAAGTGGA CGGGGCAATA CACCTACGAC


 


751
AATGTGGAGC GCACGCCCGA CCGCAGTCCG ACCAAGTCCG TGTACGACCG


 


801
CTTCGGACTG CCTTACCGCA TGGGGTTCGC CCACCGGAAC GATTTTGTCA


 


851
AAGACAAGCT GCAAGTTTGG CGTTCCGACC TTGAATACGC CTTCAACGAC


 


901
AAATGGCGTG CCCAATGGCA GCTCGCCCAC CGCACGGCGG CGCAGGATTT


 


951
TGATCATTTC TATGCAGGCA GCGAAAATGG CAACTTAATC AAACGTAACT


 


1001
ACGCCTGGCA GCAGACCGAC AACAAAACCC TGTCGTCCAA CTTAACGCTC


 


1051
AACGGCGACT ACACCATCGG CCGTTTTGAA AACCACCTGA CCGTAGGCAT


 


1101
GGATTACAGC CGCGAACACC GCAACCCGAC ATTGGGTTTC AGCAGCGCCT


 


1151
TTTCCGCCTC CATCAACCCC TACGACCGCG CAAGCTGGCC GGCTTCGGGC


 


1201
AGATTGCAGC CTATTCTGAC CCAAAACCGC CACAAAGCCG ACTCCTACGG


 


1251
CATCTTTGTG CAAAACATCT TCTCCGCCAC GCCCGATTTG AAATTCGTCC


 


1301
TCGGCGGCCG TTACGACAAA TACACCTTTA ATTCCGAAAA CAAACTCACC


 


1351
GGCAGCAGCC GCCAATACAG CGGACACTCG TTCAGCCCCA ACATCGGCGC


 


1401
AGTGTGGAAC ATCAATCCCG TCCACACACT TTACGCCTCG TATAACAAAG


 


1451
GCTTCGCGCC TTATGGCGGA CGCGGCGGCT ATTTGAGCAT CGATACGTTG


 


1501
TCTTCCGCCG TGTTCAACGC CGACCCCGAG TACACCCGCC AATACGAAAC


 


1551
CGGCGTGAAA AGCAGTTGGC TGGACGACCG CCTCAGCACT ACGTTGTCTG


 


1601
CCTACCAAAT CGAACGCTTC AATATCCGCT ACCGCCCCGA TCCAAAAAAC


 


1651
AACCCTTATA TTTATGCGGT TAGCGGCAAA CACCGTTCGC GCGGCGTGGA


 


1701
ATTGTCCGCC ATCGGGCAAA TCATCCCCAA AAAACTCTAT CTGCGCGGTT


 


1751
CGTTGGGCGT GATGCAGGCG AAAGTCGTTG AAGACAAAGA AAATCCCGAC


 


1801
CGAGTGGGCA TCCATTTGAA TAATACCAGC AACGTTACCG GCAACCTGTT


 


1851
TTTCCGTTAT ACCCCGACCG AAAACCTCTA CGGCGAAATC GGCGTAACCG


 


1901
GTACAGGCAA ACGCTACGGT TACAACTCAA GAAATAAAGA AGTGACTACG


 


1951
CTTCCAGGCT TTGCCCGAGT TGATGCCATG CTTGGCTGGA ACCATAAAAA


 


2001
TGTTAACGTT ACCTTTGCCG CAGCCAATCT GCTCAATCAA AAATATTGGC


 


2051
GTTCGGACTC TATGCCGGGT AATCCGCGCG GCTATACTGC CCGGGTAAAT


 


2101
TACCGTTTCT GA






This corresponds to the amino acid sequence <SEQ ID 2608; ORF 761>:










m761.pep




1
MKISFHLALL PTLIIASFPV AAADTQDNGE HYTATLPTVS VVGQSDTSVL


 


51
KGYINYDEAA VTRNGQLIKE TPQTIDTLNI QKNKNYGTND LSSILEGNAG


 


101
IDAAYDMRGE SIFLRGFQAD ASDIYRDGVR ESGQVRRSTA NIERVEILKG


 


151
PSSVLYGRTN GGGVINMVSK YANFKQSRNI GAVYGSWANR SLNMDINEVL


 


201
NKNVAIRLTG EVGRANSFRS GIDSKNVMVS PSITVKLDNG LKWTGQYTYD


 


251
NVERTPDRSP TKSVYDRFGL PYRMGFAHRN DFVKDKLQVW RSDLEYAFND


 


301
KWRAQWQLAH RTAAQDFDHF YAGSENGNLI KRNYAWQQTD NKTLSSNLTL


 


351
NGDYTIGRFE NHLTVGMDYS REHRNPTLGF SSAFSASINP YDRASWPASG


 


401
RLQPILTQNR HKADSYGIFV QNIFSATPDL KFVLGGRYDK YTFNSENKLT


 


451
GSSRQYSGHS FSPNIGAVWN INPVHTLYAS YNKGFAPYGG RGGYLSIDTL


 


501
SSAVFNADPE YTRQYETGVK SSWLDDRLST TLSAYQIERF NIRYRPDPKN


 


551
NPYIYAVSGK HRSRGVELSA IGQIIPKKLY LRGSLGVMQA KVVEDKENPD


 


601
RVGIHLNNTS NVTGNLFFRY TPTENLYGEI GVTGTGKRYG YNSRNKEVTT


 


651
LPGFARVDAM LGWNHKNVNV TFAAANLLNQ KYWRSDSMPG NPRGYTARVN


 


701
YRF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2609>:










a761.seq




1
ATGAAAATAT CATTTCATTT AGCTTTATTA CCCACGCTGA TTATTGCTTC


 


51
CTTCCCTGTT GCTGCCGCCG ATACGCAGGA CAATGGTGAA CATTACACCG


 


101
CCACTCTGCC CACCGTTTCC GTGGTCGGAC AGTCCGACAC CAGCGTACTC


 


151
AAAGGCTACA TCAACTACGA CGAAGCCGCC GTTACCCGCA ACGGACAGCT


 


201
CATCAAAGAA ACGCCGCAAA CCATCGATAC GCTCAATATC CAGAAAAACA


 


251
AAAATTACGG CACGAACGAT TTGAGTTCCA TCCTCGAAGG CAATGCCGGC


 


301
ATCGACGCCG CCTACGATAT GCGCGGCGAA AGCATTTTCC TGCGCGGCTT


 


351
TCAAGCCGAC GCATCTGATA TTTACCGCGA CGGCGTACGC GAAAGCGGGC


 


401
AGGTGCGCCG TAGCACCGCC AACATCGAGC GCGTGGAAAT CCTGAAAGGT


 


451
CCGTCCTCCG TGCTTTATGG GCGTACCAAC GGCGGCGGTG TCATCAACAT


 


501
GGTCAGCAAA TACGCCAACT TCAAACAAAG CCGTAATATC GGTACGGTTT


 


551
ATGGTTCGTG GGCAAACCGC AGCCTGAATA TGGACATCAA CGAAGTGCTG


 


601
AACAAAAACG TCGCCATCCG TCTCACCGGC GAAGTCGGGC GCGCCAATTC


 


651
GTTCCGCAGC GGCATAGACA GCAAAAATGT CATGGTTTCG CCCAGCATTA


 


701
CCGTCAAACT CGACAACGGC TTGAAGTGGA CGGGGCAATA CACCTACGAC


 


751
AATGTGGAGC GCACGCCCGA CCGCAGTCCG ACCAAGTCCG TGTACGACCG


 


801
CTTCGGACTG CCTTACCGCA TGGGGTTCGC CCACCGGAAC GATTTTGTCA


 


851
AAGACAAGCT GCAAGTTTGG CGTTCCGACC TTGAATACGC CTTCAACGAC


 


901
AAATGGCGTG CCCAATGGCA GCTCGCCCAC CGCACGGCGG CGCAGGATTT


 


951
TGATCATTTC TATGCAGGCA GCGAAAATGG CAACTTAATC AAACGTAACT


 


1001
ACGCCTGGCA GCAGACCGAC AACAAAACCC TGTCGTCCAA CTTAACGCTC


 


1051
AACGGCGACT ACACCATCGG CCGTTTTGAA AACCACCTGA CCGTAGGCAT


 


1101
GGATTACAGC CGCGAACACC GCAACCCGAC ATTGGGTTTC AGCAGCGCCT


 


1151
TTTCCGCCTC CATCAACCCC TACGACCGCG CAAGCTGGCC GGCTTCGGGC


 


1201
AGATTGCAGC CTATTCTGAC CCAAAACCGC CACAAAGCCG ACTCCTACGG


 


1251
CATCTTTGTG CAAAACATCT TCTCCGCCAC GCCCGATTTG AAATTCGTCC


 


1301
TCGGCGGCCG TTACGACAAA TACACCTTTA ATTCCGAAAA CAAACTCACC


 


1351
GGCAGCAGCC GCCAATACAG CGGACACTCG TTCAGCCCCA ACATCGGCGC


 


1401
AGTGTGGAAC ATCAATCCCG TCCACACACT TTACGCCTCG TATAACAAAG


 


1451
GCTTCGCGCC TTATGGCGGA CGCGGCGGCT ATTTGAGCAT CGATACGTTG


 


1501
TCTTCCGCCG TGTTCAACGC CGACCCCGAG TACACCCGCC AATACGAAAC


 


1551
CGGCGTGAAA AGCAGTTGGC TGGACGACCG CCTCAGCACT ACGTTGTCTG


 


1601
CCTACCAAAT CGAACGCTTC AATATCCGCT ACCGCCCCGA TCCAAAAAAC


 


1651
AACCCTTATA TTTATGCGGT TAGCGGCAAA CACCGTTCGC GCGGCGTGGA


 


1701
ATTGTCCGCC ATCGGGCAAA TCATCCCCAA AAAACTCTAT CTGCGCGGTT


 


1751
CGTTGGGCGT GATGCAGGCG AAAGTCGTTG AAGACAAAGA AAATCCCGAC


 


1801
CGAGTGGGCA TCCATTTGAA TAACACCAGC AACGTTACCG GCAACCTGTT


 


1851
TTTCCGTTAT ACCCCGACCG AAAACCTCTA CGGCGAAATC GGCGTAACCG


 


1901
GTACAGGCAA ACGCTACGGT TACGACTCAA GAAATAAAGA AGTGACTACG


 


1951
CTTCCAGGCT TTGCCCGAGT TGATGCCATG CTTGGCTGGA ACCATAAAAA


 


2001
TGTTAACGTT ACCTTTGCCG CAGCCAATCT GTTCAATCAA AAATATTGGC


 


2051
GTTCGGACTC TATGCCGGGT AATCCGCGCG GCTATACTGC CCGGGTAAAT


 


2101
TACCGTTTCT GA






This corresponds to the amino acid sequence <SEQ ID 2610; ORF 761.a>:










a761.pep




1
MKISFHLALL PTLIIASFPV AAADTQDNGE HYTATLPTVS VVGQSDTSVL


 


51
KGYINYDEAA VTRNGQLIKE TPQTIDTLNI QKNKNYGTND LSSILEGNAG


 


101
IDAAYDMRGE SIFLRGFQAD ASDIYRDGVR ESGQVRRSTA NIERVEILKG


 


151
PSSVLYGRTN GGGVINMVSK YANFKQSRNI GTVYGSWANR SLNMDINEVL


 


201
NKNVAIRLTG EVGRANSFRS GIDSKNVMVS PSITVKLDNG LKWTGQYTYD


 


251
NVERTPDRSP TKSVYDRFGL PYRMGFAHRN DFVKDKLQVW RSDLEYAFND


 


301
KWRAQWQLAH RTAAQDFDHF YAGSENGNLI KRNYAWQQTD NKTLSSNLTL


 


351
NGDYTIGRFE NHLTVGMDYS REHRNPTLGF SSAFSASINP YDRASWPASG


 


401
RLQPILTQNR HKADSYGIFV QNIFSATPDL KFVLGGRYDK YTFNSENKLT


 


451
GSSRQYSGHS FSPNIGAVWN INPVHTLYAS YNKGFAPYGG RGGYLSIDTL


 


501
SSAVFNADPE YTRQYETGVK SSWLDDRLST TLSAYQIERF NIRYRPDPKN


 


551
NPYIYAVSGK HRSRGVELSA IGQIIPKKLY LRGSLGVMQA KVVEDKENPD


 


601
RVGIHLNNTS NVTGNLFFRY TPTENLYGEI GVTGTGKRYG YDSRNKEVTT


 


651
LPGFARVDAM LGWNHKNVNV TFAAANLFNQ KYWRSDSMPG NPRGYTARVN


 


701
YRF*






m761/a761 99.6% identity in 703 aa overlap





g762.seq Not yet found
g762.pep Not yet found
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2611>:









m762.seq




1
ATGAAGTGGT TATTAAATAT GATAATGAGA CCTATTAAAT TTAGTATGGT


 


51
AAATACGTTA TTATTTATTG TTATATGTAG TTCATTTTTT GATCTGCTCG


 


101
TTCAATTATG TACAATTTTA TTTCATAGCC AAAAAATATA CTTTATTACA


 


151
TTATTTTTAT TATTTATTTT TAATTTTGTT ACAAAATCTA TCTATATGGC


 


201
AATTATTTAT CCTATTTTAT ATTTTTTTAC GATAAAAAAA TATTATCCTT


 


251
ACTCTAGGAA AGTGATAATT CTATTATCAT TAGCATTATC TATATATTTT


 


301
AGTTTTATGG ACTTTTACTT TTTTTCCATA TATTCAGATA ACCTTAGCTA


 


351
TGAAACGGAG CCTTTACATT TATACATCCC TATTATTATT AATTTTTTCT


 


401
CACTTTTAGT TTCTAATTTT ATTTTATCTT TTATCAACAA GTAA






This corresponds to the amino acid sequence <SEQ ID 2612; ORF 762>:










m762.pep




1
MKWLLNMIMR PIKFSMVNTL LFIVICSSFF DLLVQLCTIL FHSQKIYFIT


 


51
LFLLFIFNFV TKSIYMAIIY PILYFFTIKK YYPYSRKVII LLSLALSIYF


 


101
SFMDFYFFSI YSDNLSYETE PLHLYIPIII NFFSLLVSNF ILSFINK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2613>:










a762.seq




1
ATGAAGTGGT TATTAAATAT GATAATGAGA CCTATTAAAT TTAGTATGGT


 


51
AAATACGTTA TTATTTATTG TTATATGTAG TTCATTTTTT GATCTGCTCG


 


101
TTCAATTATG TACAATTTTA TTTCATAGCC AAAAAATATA CTTTATTACA


 


151
TTATTTTTAT TATTTATTTT TAATTTTGTT ACAAAATCTA TCTATATGGC


 


201
AATTATTTAT CCTATTTTAT ATTTTTTTAC GATAAAAAAA TATTATCCTT


 


251
ACTCTAGGAA AGTGATAATT CTATTATCAT TAGCATTATC TATATATTTT


 


301
AGTTTTATGG ACTTTTACTT TTTTTCCATA TATTCAGATA ACCTTAGCTA


 


351
TGAAACGGAG CCTTTACATT TATACATCCC TATTATTATT AATTTTTTCT


 


401
CACTTTTAGT TTCTAATTTT ATTTTATCTT TTATCAACAA GTAA






This corresponds to the amino acid sequence <SEQ ID 2614; ORF 762.a>:










a762.pep




1
MKWLLNMIMR PIKFSMVNTL LFIVICSSFF DLLVQLCTIL FHSQKIYFIT


 


51
LFLLFIFNFV TKSIYMAIIY PILYFFTIKK YYPYSRKVII LLSLALSIYF


 


101
SFMDFYFFSI YSDNLSYETE PLHLYIPIII NFFSLLVSNF ILSFINK*






m762/a762 100.0% identity in 147 aa overlap





g763.seq not yet found
g763.pep not yet found
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2615>:









m763.seq




1
ATGACATTGC TCAATCTAAT GATAATGCAA GATTACGGTA TTTCCGTTTG


 


51
CCTGACACTG ACGCCCTATT TGCAACATGA ACTATTTTCG GCTATGAAAT


 


101
CCTATTTTTC CAAATATATC CTACCCGTTT CACTTTTTAC CTTGCCACTA


 


151
TCCCTTTCCC CATCCGTTTC GGCTTTTACG CTGCCTGAAG CATGGCGGGC


 


201
GGCGCAGCAA CATTCGGCTG ATTTTCAAGC GTCCCATTAC CAGCGTGATG


 


251
CAGTGCGCGC ACGGCAACAA CAAGCCAAGG CCGCATTCCT TCCCCATGTA


 


301
TCCGCCAATG CCAGCTACCA GCGCCAGCCG CCATCGATTT CTTCCACCCG


 


351
CGAAACACAG GGATGGAGCG TGCAGGTGGG ACAAACCTTA TTTGACGCTG


 


401
CCAAATTTGC ACAATACCGC CAAAGCAGGT TCGATACGCA GGCTGCAGAA


 


451
CAGCGTTTCG ATGCGGCACG CGAAGAATTG CTGTTGAAAG TTGCCGAAAG


 


501
TTATTTCAAC GTTTTACTCA GCCGAGACAC CGTTGCCGCC CATGCGGCGG


 


551
AAAAAGAGGC TTATGCCCAG CAGGTAAGGC AGGCGCAGGC TTTATTCAAT


 


601
AAAGGTGCTG CCACCGCGCT GGATATTCAC GAAGCCAAAG CCGGTTACGA


 


651
CAATGCCCTG GCCCAAGAAA TCGCCGTATT GGCTGAGAAA CAAACCTATG


 


701
AAAACCAGTT GAACGACTAC ACCGACCTGG ATAGCAAACA AATCGAGGCC


 


751
ATAGATACCG CCAACCTGTT GGCACGCTAT CTGCCCAAGC TGGAACGTTA


 


801
CAGTCTGGAT GAATGGCAGC GCATTGCCTT ATCCAACAAT CATGAATACC


 


851
GGATGCAGCA GCTTGCCCTG CAAAGCAGCG GACAGGCGCT TCGGGCAGCA


 


901
CAGAACAGCC GCTATCCCAC CGTTTCTGCC CATGTCGGCT ATCAGAATAA


 


951
CCTCTACACT TCATCTGCGC AGAATAATGA CTACCACTAT CGGGGCAAAG


 


1001
GGATGAGCGT CGGCGTACAG TTGAATTTGC CGCTTTATAC CGGCGGAGAA


 


1051
TTGTCGGGCA AAATCCATGA AGCCGAAGCG CAATACGGGG CCGCCGAAGC


 


1101
ACAGCTGACC GCAACCGAGC GGCACATCAA ACTCGCCGTA CGCCAGGCTT


 


1151
ATACCGAAAG CGGTGCGGCG CGTTACCAAA TCATGGCGCA AGAACGGGTT


 


1201
TTGGAAAGCA GCCGTTTGAA ACTGAAATCG ACCGAAACCG GCCAACAATA


 


1251
CGGCATCCGC AACCGGCTGG AAGTAATACG GGCGCGGCAG GAAGTCGCCC


 


1301
AAGCAGAACA GAAACTGGCT CAAGCACGGT ATAAATTCAT GCTGGCTTAT


 


1351
TTGCGCTTGG TGAAAGAGAG CGGGTTAGGG TTGGAAACGG TATTTGCGGA


 


1401
ATAA






This corresponds to the amino acid sequence <SEQ ID 2616; ORF 763>:










m763.pep




1
MTLLNLMIMQ DYGISVCLTL TPYLQHELFS AMKSYFSKYI LPVSLFTLPL


 


51
SLSPSVSAFT LPEAWRAAQQ HSADFQASHY QRDAVRARQQ QAKAAFLPHV


 


101
SANASYQRQP PSISSTRETQ GWSVQVGQTL FDAAKFAQYR QSRFDTQAAE


 


151
QRFDAAREEL LLKVAESYFN VLLSRDTVAA HAAEKEAYAQ QVRQAQALFN


 


201
KGAATALDIH EAKAGYDNAL AQEIAVLAEK QTYENQLNDY TDLDSKQIEA


 


251
IDTANLLARY LPKLERYSLD EWQRIALSNN HEYRMQQLAL QSSGQALRAA


 


301
QNSRYPTVSA HVGYQNNLYT SSAQNNDYHY RGKGMSVGVQ LNLPLYTGGE


 


351
LSGKIHEAEA QYGAAEAQLT ATERHIKLAV RQAYTESGAA RYQIMAQERV


 


401
LESSRLKLKS TETGQQYGIR NRLEVIRARQ EVAQAEQKLA QARYKFMLAY


 


451
LRLVKESGLG LETVFAE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2617>:










a763.seq




1
ATGACATTGC TCAATCTAAT GATAATGCAA GATTACGGTA TTTCCGTTTG


 


51
CCTGACACTG ACGCCCTATT TGCAACATGA ACTATTTTCG GCTATGAAAT


 


101
CCTATTTTTC CAAATATATC CTACCCGTTT CACTTTTTAC CTTGCCACTA


 


151
TCCCTTTCCC CATCCGTTTC GGCTTTTACG CTGCCTGAAG CATGGCGGGC


 


201
GGCGCAGCAA CATTCGGCTG ATTTTCAAGC GTCCCATTAC CAGCGTGATG


 


251
CAGTGCGCGC ACGGCAACAA CAAGCCAAGG CCGCATTCCT TCCCCATGTA


 


301
TCCGCCAATG CCAGCTACCA GCGCCAGCCG CCATCGATTT CTTCCACCCG


 


351
CGAAACACAG GGATGGAGCG TGCAGGTGGG ACAAACCTTA TTTGACGCTG


 


401
CCAAATTTGC ACAATACCGC CAAAGCAGGT TCGATACGCA GGCTGCAGAA


 


451
CAGCGTTTCG ATGCGGCACG CGAAGAATTG CTGTTGAAAG TTGCCGAAAG


 


501
TTATTTCAAC GTTTTACTCA GCCGAGACAC CGTTGCCGCC CATGCGGCGG


 


551
AAAAAGAGGC TTATGCCCAG CAGGTAAGGC AGGCGCAGGC TTTATTCAAT


 


601
AAAGGTGCTG CCACCGCGCT GGATATTCAC GAAGCCAAAG CCGGTTACGA


 


651
CAATGCCCTG GCCCAAGAAA TCGCCGTATT GGCTGAGAAA CAAACCTATG


 


701
AAAACCAGTT GAACGACTAC ACCGGCCTGG ACAGCAAACA AATCGAGGCC


 


751
ATAGATACCG CCAACCTGTT GGCACGCTAT CTGCCGAAGC TGGAACGTTA


 


801
CAGTCTGGAT GAATGGCAGC GCATTGCCTT ATCCAACAAT CATGAATACC


 


851
GGATGCAGCA GCTTGCCCTG CAAAGCAGCG GACAGGCGCT TCGGGCAGCA


 


901
CAGAACAGCC GCTATCCCAC CGTTTCTGCC CATGTCGGCT ATCAGAATAA


 


951
CCTCTACACT TCATCTGCGC AGAATAATGA CTACCACTAT CGGGGCAAAG


 


1001
GGATGAGCGT CGGCGTACAG TTGAATTTGC CGCTTTATAC CGGCGGAGAA


 


1051
TTGTCGGGCA AAATCCATGA AGCCGAAGCG CAATACGGGG CTGCCGAAGC


 


1101
ACAGCTGACC GCAACCGAGC GGCACATCAA ACTCGCCGTA CGCCAGGCTT


 


1151
ATACCGAAAG CGGTGCGGCG CGTTACCAAA TCATGGCGCA AGAACGGGTT


 


1201
TTGGAAAGCA GCCGTTTGAA ACTGAAATCG ACCGAAACCG GCCAACAATA


 


1251
CGGCATCCGC AACCGGCTGG AAGTAATACG GGCGCGGCAG GAAGTCGCCC


 


1301
AAGCAGAACA GAAACTGGCT CAAGCACGGT ATAAATTCAT GCTGGCTTAT


 


1351
TTGCGCTTGG TGAAAGAGAG CGGGTTAGGG TTGGAAACGG TATTTGCGGA


 


1401
ATAA






This corresponds to the amino acid sequence <SEQ ID 2618; ORF 763.a>:










a763.pep




1
MTLLNLMIMQ DYGISVCLTL TPYLQHELFS AMKSYFSKYI LPVSLFTLPL


 


51
SLSPSVSAFT LPEAWRAAQQ HSADFQASHY QRDAVRARQQ QAKAAFLPHV


 


101
SANASYQRQP PSISSTRETQ GWSVQVGQTL FDAAKFAQYR QSRFDTQAAE


 


151
QRFDAAREEL LLKVAESYFN VLLSRDTVAA HAAEKEAYAQ QVRQAQALFN


 


201
KGAATALDIH EAKAGYDNAL AQEIAVLAEK QTYENQLNDY TGLDSKQIEA


 


251
IDTANLLARY LPKLERYSLD EWQRIALSNN HEYRMQQLAL QSSGQALRAA


 


301
QNSRYPTVSA HVGYQNNLYT SSAQNNDYHY RGKGMSVGVQ LNLPLYTGGE


 


351
LSGKIHEAEA QYGAAEAQLT ATERHIKLAV RQAYTESGAA RYQIMAQERV


 


401
LESSRLKLKS TETGQQYGIR NRLEVIRARQ EVAQAEQKLA QARYKFMLAY


 


451
LRLVKESGLG LETVFAE*






m763/a763 99.8% identity in 467 aa overlap





g764.seq not found yet
g764.pep not found yet
The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2619>:









m764.seq




1
ATGTTTTTCT CCGCCCTGAA ATCCTTTCTT TCTCGATACA TTACTGTATG


 


51
GCGCAATGTT TGGGCGGTGC GCGACCAGTT GAAACCGCCC AAACGCACGG


 


101
CGGAAGAACA GGCGTTTTTG CCCGCGCATT TGGAACTGAC CGATACGCCG


 


151
GTCTCTGCCG CTCCGAAATG GGCGGCGCGT TTTATTATGG CGTTTGCGCT


 


201
TTTGGCTTTG TTGTGGTCCT GGTTCGGCAA AATCGATATT GTGGCGGCGG


 


251
CTTCGGGCAA AACGGTGTCG GGCGGGCGCA GCAAAACCAT CCAGCCGCTG


 


301
GAAACGGCGG TGGTTAAGGC GGTACATGTG CGCGACGGGC AGCATGTGAA


 


351
ACAGGGAGAA ACGCTGGCGG AACTGGAGGC TGTGGGAACA GACAGCGATG


 


401
TGGTGCAGTC GGAGCAGGCT TTGCAGGCTG CCCAATTGTC CAAACTGCGT


 


451
TATGAAGCGG TATTGGCGGC ATTGGAAAGC CGTACCGTGC CGCATATCGA


 


501
TATGGCGCAA GCACGGTCTT TAGGTCTCTC CGATGCCGAT GTGCAATCGG


 


551
CGCAGGTGTT GGCGCAGCAC CAGTATCAGG CATGGGCGGC GCAGGATGCG


 


601
CAATTGCAGT CGGCTTTGCG CGGCCATCAG GCGGAATTGC AGTCGGCCAA


 


651
GGCGCAGGAG CAGAAGCTGG TTTCGGTGGG GGCGATCGAG CAGCAGAAAA


 


701
CAGCAGACTA CCGCCGTTTG CGGGCCGACA ATTTTATTTC GGAACATGCG


 


751
TTTTTGGAGC AGCAGAGCAA ATCGGTCAGC AATTGGAACG ATTTGGAAAG


 


801
TACGCGCGGT CAGATGAGGC AGATTCAGGC GGCCATTGCA CAGGCGGAGC


 


851
AGAATCGGGT GCTGAATACG CAGAACCTGA AACGCGATAC GCTGGATGCG


 


901
CTGCGCCAGG CAAACGAACA GATTGACCAA TACCGCGGCC AAACGGATAA


 


951
GGCAAAGCAG CGGCAGCAGC TGATGACAAT ACAGTCGCCT GCGGACGGCA


 


1001
CGGTGCAGGA ATTGGCTACC TATACGGTGG GCGGTGTGGT GCAGGCTGCC


 


1051
CAAAAAATGA TGGTGATTGC GCCCGATGAC GACAAAATGG ACGTGGAAGT


 


1101
TTTGGTATTG AACAAAGACA TCGGTTTTGT GGAACAGGGA CAGGATGCGG


 


1151
TGGTGAAGAT TGAGAGCTTT CCCTATACGC GCTACGGTTA TCTGACGGGC


 


1201
AAGGTGAAAA GTGTCAGCCA TGATGCGGTA AGCCACGAAC AGTTGGGCTT


 


1251
GGTTTATACG GCGGTGGTGT CGCTGGACAA ACATACCTTG AATATTGACG


 


1301
GCAAAGCAGT GAATCTGACG GCGGGCATGA ATGTCACGGC GGAGATTAAA


 


1351
ACGGGTAAAC GGCGGGTGCT GGATTATCTG TTAAGCCCGC TGCAAACCAA


 


1401
ATTGGACGAA AGCTTTAGGG AGCGATAG






This corresponds to the amino acid sequence <SEQ ID 2620; ORF 764>:










m764.pep




1
MFFSALKSFL SRYITVWRNV WAVRDQLKPP KRTAEEQAFL PAHLELTDTP


 


51
VSAAPKWAAR FIMAFALLAL LWSWFGKIDI VAAASGKTVS GGRSKTIQPL


 


101
ETAVVKAVHV RDGQHVKQGE TLAELEAVGT DSDVVQSEQA LQAAQLSKLR


 


151
YEAVLAALES RTVPHIDMAQ ARSLGLSDAD VQSAQVLAQH QYQAWAAQDA


 


201
QLQSALRGHQ AELQSAKAQE QKLVSVGAIE QQKTADYRRL RADNFISEHA


 


251
FLEQQSKSVS NWNDLESTRG QMRQIQAAIA QAEQNRVLNT QNLKRDTLDA


 


301
LRQANEQIDQ YRGQTDKAKQ RQQLMTIQSP ADGTVQELAT YTVGGVVQAA


 


351
QKMMVIAPDD DKMDVEVLVL NKDIGFVEQG QDAVVKIESF PYTRYGYLTG


 


401
KVKSVSHDAV SHEQLGLVYT AVVSLDKHTL NIDGKAVNLT AGMNVTAEIK


 


451
TGKRRVLDYL LSPLQTKLDE SFRER*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2621>:









a764.seq (partial)










1
ATGTTTTTCT CCGCCCTGAA ATCCTTTCTT TCCCGCTACA TTACCGTATG



 


51
GCGCAATGTT TGGGCGGTGC GCGACCAGTT GGAACCGCCC AAACGCACGG


 


101
CGGAAGAACA GGCGTTTTTG CCCGCGCATT TGGAACTGAC CGATACGCCG


 


151
GTCTCTGCCG CTCCGAAATG GGCGGCGCGT TTTATTATGG CGTTTGCGCT


 


201
TTTGGCTTTG TTGTGGTCCT GGTTCGGCAA AATCGATATT GTGGCGGCGG


 


251
CTTCGGGCAA AACGGTGTCG GGCGGGCGCA GCAAAACCAT CCAGCCGCTG


 


301
GAAACGGTGG TGGTTAAGGC GGTACATGTG CGCGACGGGC AGCATGTGAA


 


351
ACAGGGAGAA ACGCTGGCGG AACTGGAGGC TGTGGGAACA GACAGCGATG


 


401
TGGTGCAGTC GGAGCAGGCT TTGCAGGCTG CCCAATTGTC CAAACTGCGT


 


451
TATGAAGCGG TATTGGCGGC ATTGGAAAGC CGTACCGTGC CGCATATCGA


 


501
TATGGCGCAA GCACGGTCTT TAGGTCTCTC CGATGCCGAT GTGCAATCGG


 


551
CGCAGGTGTT GGCGCAGCAC CAGTATCAGG CATGGGCGGC GCAGGATGCG


 


601
CAATTGCAGT CGGCTTTGCG CGGCCATCAG GCGGAATTGC AGTCGGCCAA


 


651
GGCGCAGGAG CAGAAGCTGG TTTCGGTGGG GGCGATCGAG CAGCAGAAAA


 


701
CAGCAGACTA CCGCCGTTTG CGGGCCGACA ATTTTATTTC GGAACATGCG


 


751
TTTTTGGAGC AGCAGAGCAA ATCGGTCAGC AATTGGAACG ATTTGGAAAG


 


801
TACGCGCGGT CAGATGAGGC AGATTCAGGC GGCCATTGCA CAGGCGGAGC


 


851
AGAATCGGGT GCTGAATACG CAGAACCTGA AACGCGATAC GCTGGATGCG


 


901
CTGCGCCAGG CAAACGAACA GATTGACCAA TACCGCGGCC AAACGGATAA


 


951
GGCAAAGCAG CGGCAGCAGC TGATGACAAT ACAGTCGCCT GCGGACGGCA


 


1001
CGGTGCAGGA ATTGGCCACC TATACGGTGG GCGGTGTGGT GCAGGCTGCC


 


1051
CAAAAAATGA TGGTGGTTGC GCCCGATGAC GACAAAATGG ACGTGGAAGT


 


1101
TTTGGTATTG AACAAAGACA TCGGTTTTGT GGAACAGGGA CAGGATGCGG


 


1151
TGGTGAAGAT TGAGAGTTTT CCCTATACGC GCTACGGTTA TCTGACGGGC


 


1201
AAGGTGAAAA GTGTCAGCCA TGATGCGGTA AGCCACGAAC AGTTGGGCTT


 


1251
GGTTTATACG GCGGTGGTGT CGCTGGACAA ACATACCTTG AATATTGACG


 


1301
GCAAA






This corresponds to the amino acid sequence <SEQ ID 2622; ORF 764.a>:









a764.pep (partial)










1
MFFSALKSFL SRYITVWRNV WAVRDQLEPP KRTAEEQAFL PAHLELTDTP



 


51
VSAAPKWAAR FIMAFALLAL LWSWFGKIDI VAAASGKTVS GGRSKTIQPL


 


101
ETVVVKAVHV RDGQHVKQGE TLAELEAVGT DSDVVQSEQA LQAAQLSKLR


 


151
YEAVLAALES RTVPHIDMAQ ARSLGLSDAD VQSAQVLAQH QYQAWAAQDA


 


201
QLQSALRGHQ AELQSAKAQE QKLVSVGAIE QQKTADYRRL RADNFISEHA


 


251
FLEQQSKSVS NWNDLESTRG QMRQIQAAIA QAEQNRVLNT QNLKRDTLDA


 


301
LRQANEQIDQ YRGQTDKAKQ RQQLMTIQSP ADGTVQELAT YTVGGVVQAA


 


351
QKMMVVAPDD DKMDVEVLVL NKDIGFVEQG QDAVVKIESF PYTRYGYLTG


 


401
KVKSVSHDAV SHEQLGLVYT AVVSLDKHTL NIDGK






m764/a764 99.3% identity in 435 aa overlap





g765.seq not yet found

g765.pep not yet found

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2623>:










m765.seq




1
ATGTTAAGAT GCCGTCCGAA ATCCGTTTTG GATTCAGACG GCATTTTTTT


 


51
GAAATTTAAT TTTTTAAGGA GTAAACCTAA ATATGAAATT TCCTTCCTTC


 


101
CTTCCTTTAA ACGGATACTC TGCCTGTCGG CAGTAATCTC GGTATTGGGG


 


151
GCTTGTGCGG TCGTTGCTGA TGTTTACGGT CATGATTCCG CCACAATGAA


 


201
CGCTGCGGCT GCCAAAGATT ATATGAAAAC GGTTGAGTTA AACAAGTCTG


 


251
CCGGCAATGT CGATACCACA TCCAGAACAG CCCGCAGGGT GCAGGCAGTA


 


301
TTTCGACGTA TGCTGCCTTA TGCCGATGCG GCAAATAATA CCAGCCATAA


 


351
GTTTGACTGG AAAATGACGG TTTTCAAAAA CGATGAGCTG AACGCGTGGG


 


401
CAATGCCCGG TGGAAAAATG GCGTTTTATA CGGGGATAGT CGACAAACTC


 


451
AAGCTGACCG ATGACGAAAT TGCCGCCATT ATGGGGCATG AAATGACGCA


 


501
CGCCCTGCAT GAACACGGTA AAAATAAGGT CGGGCAGCAA ATCTTGACCA


 


551
ATACGGCGGC GCAGATAGGC ACGCAGATTA TATTAGACAA AAAACCGGAT


 


601
ACTAATCCGG AATTGGTCGG ATTGGGTATG GATATTTTGG GGACGTACGG


 


651
TCTTACCTTG CCTTATAGCC GCAGCTTGGA AGAAGAAGCC GATGAGGGGG


 


701
GAATGATGTT GATGGCGCAG GCAGGCTATC ATCCGGCGGC CGCTGTCAGG


 


751
GTTTGGGAAA AAATGAATCA GGAAAACGAC CAAAACGGCT TTATTTATGC


 


801
TATTACCTCT ACTCATCCGA CAAACAATGC CCGTATAGAA AATCTAAAAC


 


851
GGTTGTTGCC GACCGTTATG CCGGTTTATG AGCAAAGTGT CAGAAATAAG


 


901
GGGCGCGTTA ATAAAAAACG TCGGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 2624; ORF 765>:










m765.pep




1
MLRCRPKSVL DSDGIFLKFN FLRSKPKYEI SFLPSFKRIL CLSAVISVLG


 


51
ACAVVADVYG HDSATMNAAA AKDYMKTVEL NKSAGNVDTT SRTARRVQAV


 


101
FRRMLPYADA ANNTSHKFDW KMTVFKNDEL NAWAMPGGKM AFYTGIVDKL


 


151
KLTDDEIAAI MGHEMTHALH EHGKNKVGQQ ILTNTAAQIG TQIILDKKPD


 


201
TNPELVGLGM DILGTYGLTL PYSRSLEEEA DEGGMMLMAQ AGYHPAAAVR


 


251
VWEKMNQEND QNGFIYAITS THPTNNARIE NLKRLLPTVM PVYEQSVRNK


 


301
GRVNKKRRR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2625>:










a765.seq




1
ATGTTAAGAT GCCGTCCGAA ATCCGTTTTG GATTCAGACG GCATTTTTTT


 


51
GAAATTTAAT TTTTTAAGGA GTAAACCTAA ATATGAAATT TCCTTCCTTC


 


101
CTTCCTTTAA ACGGATACTC TGCCTGTCGG CAGTAATCTC GGTATTGGGG


 


151
GCTTGTACGG TCGTTGCTGA TGTTTACGGT CAGGATTCCG CCACAATGAA


 


201
TGCTGCGGCT GCCGAAGATT ATATGAAAAC GGTTGAGTTG AACAAGTCTG


 


251
CCGGCAATGT CGATACTACA TCCAAAACAG CCCGTAGGGT GCAGGCAGTA


 


301
TTTCGACGTA TGTTGCCTTA TGCCGATGCG GCAAATAATA CCGGCCATAA


 


351
GTTTGACTGG AAAATGACGG TTTTCAAAAA CGATGAGCTG AACGCGTGGG


 


401
CAATGCCCGG CGGGAAAATG GCGTTTTATA CGGGGATAGT CGATAAACTT


 


451
AAGCTGACCG ATGGCGAAAT TGCCGCCATT ATGGGGCATG AAATGACGCA


 


501
TGCCCTGCAT GAACACGGTA AAAATAAGGT CGGGCAGAAA ATCTTGACTA


 


551
ATATGGCGGC GCAGATAGGC ACGCAGATTA TATTAGACAA AAAACCGGAC


 


601
ACTAATCCGG AATTGGTCGG ATTGGGTATG GATATTTTGG GGATGTACGG


 


651
CATTACCTTG CCTTATAGCC GCAGCTTGGA AGAAGAAGCC GATGAGGGGG


 


701
GAATGATGTT GATGGCGCAG GCAGGCTATC ATCCGGCAGC CGCTGTCAGG


 


751
GTTTGGGAAA AAATGAATCA GGAAAACGAC CAAAACGGCT TTATTTATGC


 


801
TATTACCTCT ACTCATCCGA CAAACAATGC CCGTATAGAA AATCTAAAAC


 


851
GGTTGTTGCC GACCGTTATG CCGGTTTATG AGCACAGTGT TAGAAATAAG


 


901
GGGCGCGTTA ATAAAAACCG TCGGCGTTAA






This corresponds to the amino acid sequence <SEQ ID 2626; ORF 765.a>:










a765.pep




1
MLRCRPKSVL DSDGIFLKFN FLRSKPKYEI SFLPSFKRIL CLSAVISVLG


 


51
ACTVVADVYG QDSATMNAAA AEDYMKTVEL NKSAGNVDTT SKTARRVQAV


 


101
FRRMLPYADA ANNTGHKFDW KMTVFKNDEL NAWAMPGGKM AFYTGIVDKL


 


151
KLTDGEIAAI MGHEMTHALH EHGKNKVGQK ILTNMAAQIG TQIILDKKPD


 


201
TNPELVGLGM DILGMYGITL PYSRSLEEEA DEGGMMLMAQ AGYHPAAAVR


 


251
VWEKMNQEND QNGFIYAITS THPTNNARIE NLKRLLPTVM PVYEHSVRNK


 


301
GRVNKNRRR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 765 shows 96.18% identity over a 309 aa overlap with a predicted ORF (ORF 765) from N. meningitidis: 

m765/a765 96.1% identity in 309 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2627>:










g767.seq




1
ATGAAGTTTA AACATCTGTT GCCGCTGCTG CTGTCGGCAG TGTTGTCCGC


 


51
GCAGGCATAT GCCCTGACGG AAGGGGAAGA CTATCTTGTG TTGGATAAAC


 


101
CCATTCCTCA AGAACAGCCG GGAAAAATTG AGGTTTTGGA ATTTTTCGGC


 


151
TATTTTTGCG TACATTGCCA TCATTTCGAT CCTTTGTTAT TGAAACTGGG


 


201
CAAGGCATTG CCGTCTGATA CTTATCTGCG GACGGAGCAC GTGGTCTGGC


 


251
GGCCTGAAAT GCTCGGTCTG GCAAGAATGG CTGCTGCGGT CAAGCTGTCG


 


301
GGTTTGAAAT ATCAGGCAAA CTCTGCTGTG TTTAAAGCAG TTTACGAACA


 


351
AAAAATCCGT TTGGAAAACA GGGCTGTTGC CGGGAAATGG GCTTTATCTC


 


401
AAAAAGGTTT TGACGGCAAA AAACTGATGC GCGCCTATGA TTCCCCCGAA


 


451
GCTGCCGCCG TCGCATTAAA AATGCAGAAA CTGACGGAAC AATACGGTAT


 


501
TGACAGCACG CCGACCGTTA TTGTCGGCGG AAAATACCGC GTTATCTTCA


 


551
ATAATGGCTT TGATGGCGGC GTTCATACGA TTAAAGAATT GGTTGCCAAA


 


601
GTCAGGGAAG AACGCAAGCG TCAGACCCCT GCTGTACAGA AATAG






This corresponds to the amino acid sequence <SEQ ID 2628; ORF 767.ng>:










g767.pep




1
MKFKHLLPLL LSAVLSAQAY ALTEGEDYLV LDKPIPQEQP GKIEVLEFFG


 


51
YFCVHCHHFD PLLLKLGKAL PSDTYLRTEH VVWRPEMLGL ARMAAAVKLS


 


101
GLKYQANSAV FKAVYEQKIR LENRAVAGKW ALSQKGFDGK KLMRAYDSPE


 


151
AAAVALKMQK LTEQYGIDST PTVIVGGKYR VIFNNGFDGG VHTIKELVAK


 


201
VREERKRQTP AVQK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2629>:










m767.seq




1
ATGAAGCTCA AACATCTGTT GCCGCTGCTG CTGTCGGCAG TGTTGTCCGC


 


51
GCAGGCATAT GCCCTGACGG AAGGGGAAGA CTATCTTGTG TTGGATAAAC


 


101
CCATTCCTCA AGAACAGTCG GGTAAAATTG AGGTTTTGGA ATTTTTCGGC


 


151
TATTTCTGCG TACATTGCCA TCATTTCGAT CCTTTGTTAT TGAAACTGGG


 


201
CAAGGCATTG CCGTCTGATG CCTATTTGAG GACGGAGCAC GTGGTCTGGC


 


251
AGCCTGAAAT GCTCGGTTTG GCTAGGATGG CGGCTGCCGT CAATTTGTCG


 


301
GGTTTGAAAT ATCAGGCAAA CCCTGCTGTG TTTAAAGCAG TTTACGAACA


 


351
AAAAATCCGC TTGGAAAACA GGTCGGTTGC CGGAAAATGG GCTTTGTCTC


 


401
AAAAAGGCTT TGACGGCAAA AAACTGATGC GCGCCTATGA TTCCCCCGAA


 


451
GCTGCCGCCG CCGCATTAAA AATGCAGAAA CTGACGGAAC AATACCGCAT


 


501
CGACAGCACG CCGACCGTTA TTGTCGGCGG AAAATACCGC GTTATCTTCA


 


551
ATAACGGCTT TGACGGCGGC GTTCATACGA TTAAAGAATT GGTTGCCAAA


 


601
GTCAGGGAAG AACGCAAGCG TCAGACCCCT GCTGTACAGA AATAG






This corresponds to the amino acid sequence <SEQ ID 2630; ORF 767>:










m767.pep




1
MKLKHLLPLL LSAVLSAQAY ALTEGEDYLV LDKPIPQEQS GKIEVLEFFG


 


51
YFCVHCHHFD PLLLKLGKAL PSDAYLRTEH VVWQPEMLGL ARMAAAVNLS


 


101
GLKYQANPAV FKAVYEQKIR LENRSVAGKW ALSQKGFDGK KLMRAYDSPE


 


151
AAAAALKMQK LTEQYRIDST PTVIVGGKYR VIFNNGFDGG VHTIKELVAK


 


201
VREERKRQTP AVQK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 767 shows 95.8% identity over a 214 aa overlap with a predicted ORF (ORF 767) from N. gonorrhoeae 

m767/g767 95.8% identity in 214 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2631>:










a767.seq




1
ATGAAGCTCA AACATCTGTT GCCGCTGCTG CTGTCGGCAG TGTTGTCCGC


 


51
GCAGGCATAT GCCCTGACGG AAGGGGAAGA CTATCTTGTG TTGGATAAAC


 


101
CCATTCCTCA AAAACAGTCG GGCAAAATTG AGGTTTTGGA ATTTTTCGGC


 


151
TATTTCTGCG TACATTGCCA TCATTTCGAT CCTTTGTTAT TGAAATTGGG


 


201
CAAGGCATTG CCGTCTGATG CCTATTTAAG GACGGAGCAC GTGGTCTGGC


 


251
AGCCTGAAAT GCTCGGTCTG GCAAGAATGG CTGCTGCGGT CAAGCTGTCA


 


301
GGTTTGAAAT ATCAGGCAAA CCCTGCCGTG TTTAAAGCAG TTTACGAACA


 


351
AAAAATCCGC TTGGAAAACA GGTCGGTTGC CGAAAAATGG GCTTTGTCTC


 


401
AAAAAGGCTT TGACGGCAAA AAACTGATGC GCGCCTACGA CTCTCCTGCG


 


451
GCAGCGGCTG CTGCATCAAA AATGCAGCAA TTGACGGAAC AGTACCGCAT


 


501
CGACAGTACG CCGACCGTTG TCGTCGGCGG AAAATACCGC GTTATCTTCA


 


551
ATAATGGCTT TGACGGCGGT GTTCATACGA TTAAAGAATT GGTTGCCAAA


 


601
GTCAGGGAAG AACGCAAGCG TCAGACCCCT GCTGTACAGA AATAG






This corresponds to the amino acid sequence <SEQ ID 2632; ORF 767.a>:










a767.pep




1
MKLKHLLPLL LSAVLSAQAY ALTEGEDYLV LDKPIPQKQS GKIEVLEFFG


 


51
YFCVHCHHFD PLLLKLGKAL PSDAYLRTEH VVWQPEMLGL ARMAAAVKLS


 


101
GLKYQANPAV FKAVYEQKIR LENRSVAEKW ALSQKGFDGK KLMRAYDSPA


 


151
AAAAASKMQQ LTEQYRIDST PTVVVGGKYR VIFNNGFDGG VHTIKELVAK


 


201
VREERKRQTP AVQK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 767 shows 96.7% identity over a 214 aa overlap with a predicted ORF (ORF 767) from N. meningitidis: 

m767/a767 96.7% identity in 214 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2633>:










g768.seq




1
ATGAATATCA AACAATTGAT TACCGCCGCA CTCATTGCCT CAGCCGCCTT


 


51
TGCCACGCAG GCAGCCCCGC AAAAACCCGT ATCCGCCGCC CAAACCGCGC


 


101
AACATTCAGC CGTTTGGATC GATGTCCGTT CCGAACAGGA ATTTAGCGAA


 


151
GGTCATTTGC ACAACGCGGT CAACATCCCC GTCGACCAAA TCGTCCGCCG


 


201
CATATACGAA GCCGCGCCCG ACAAAGACAC GCCGGTCAAC CTCTACTGCC


 


251
GCAGCGGACG GCGTGCCGAA GCCGCCCTTC AAGAGCTGAA AAAAGCAGGT


 


301
TATACAAATG TTGCCAATCA CGGCGGTTAT GAAGACCTGC TCAAAAAAGG


 


351
GATGAAATGA






This corresponds to the amino acid sequence <SEQ ID 2634; ORF 768.ng>:










g768.pep




1
MNIKQLITAA LIASAAFATQ AAPQKPVSAA QTAQHSAVWI DVRSEQEFSE


 


51
GHLHNAVNIP VDQIVRRIYE AAPDKDTPVN LYCRSGRRAE AALQELKKAG


 


101
YTNVANHGGY EDLLKKGMK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2635>:










m768.seq




1
ATGAATATCA AACACCTGAT TACCGCCGCA CTCATTGCCT CAGCCGCCTT


 


51
TGCCGCGCAG GCAGCCCCGC AAAAACCCGT ATCCGCCGCC CAAACCGCGC


 


101
AACATCCGGC CGTTTGGATC GATGTCCGTT CCGAACAGGA ATTTAGCGAA


 


151
GGGCATTTGC ACAACGCGGT CAACATCCCC GTCGACCAAA TCGTCCGCCG


 


201
CATACACGAA GCCGCGCCCG ACAAAGACAC GCCGGTCAAC CTCTACTGCC


 


251
GCAGCGGACG GCGTGCCGAA GCCGCCCTTC AAGAGCTGAA AAAAGCAGGT


 


301
TATACAAATG TTGCCAATCA CGGCGGTTAT GAAGACCTGC TCAAAAAAGG


 


351
GATGAAATGA






This corresponds to the amino acid sequence <SEQ ID 2636; ORF 768>:










m768.pep




1
MNIKHLITAA LIASAAFAAQ AAPQKPVSAA QTAQHPAVWI DVRSEQEFSE


 


51
GHLHNAVNIP VDQIVRRIHE AAPDKDTPVN LYCRSGRRAE AALQELKKAG


 


101
YTNVANHGGY EDLLKKGMK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 768 shows 96.6% identity over a 119 aa overlap with a predicted ORF (ORF 768) from N. gonorrhoeae 

m768/g768 96.6% identity in 119 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2637>:










a768.seq




1
ATGAATATCA AACACCTGAT TACCGCCGCA CTCATTGCCT CAGCCGCCTT


 


51
TGCCGCGCAG GCAGCCCCGC AAAAACCCGT ATCCGCCGCC CAAACCGCGC


 


101
AACATTCAGC CGTTTGGATC GATGTCCGCA GCGAACAGGA ATTTAGCGAA


 


151
GGTCATTTGC ACAACGCGGT CAACATCCCC GTCGACCAAA TCGTCCGCCG


 


201
CATACACGAA GCCGCGCCCG ACAAAGACAC GCCGGTCAAC CTCTACTGCC


 


251
GCAGCGGACG GCGTGCCGAA GCCGCCCTTC AAGAACTGAA AAAAGCAGGC


 


301
TATACGAATG TTGCCAATCA CGGCGGTTAT GAAGACCTGC TCAAAAAAGG


 


351
GATGAAATGA






This corresponds to the amino acid sequence <SEQ ID 2638; ORF 768.a>:










a768.pep




1
MNIKHLITAA LIASAAFAAQ AAPQKPVSAA QTAQHSAVWI DVRSEQEFSE


 


51
GHLHNAVNIP VDQIVRRIHE AAPDKDTPVN LYCRSGRRAE AALQELKKAG


 


101
YTNVANHGGY EDLLKKGMK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 768 shows 99.2% identity over a 119 aa overlap with a predicted ORF (ORF 768) from N. meningitidis: 

m768/a768 99.2% identity in 119 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2639>:










g769.seq




1
TTGATAATGG TTATTTTTTA TTTTTATTTT TGTGGGAAGA CATTTATGCC


 


51
TGCACGAAAC AGATGGATGC TGCTGCCTTT ATTGGCAAGC GCGGCATACG


 


101
CCGAAgaAAC ACCgtgCGAA CCGGATTTGA GAAGCCGTCC CGAGTTCAGG


 


151
CTTCATGAAG CGGAGGTCAA ACCGATCGAC AGGGAGAAGG TACCGGGGCA


 


201
GGTGCGGGAA AAAGGAAAAG TTTTGCAGGT TGACGgcGAA ACCCTGCTGA


 


251
AAAATCCCGA ATTGTTGTCG CGTGCCATGT ATTCCGCAGT GGTCTCAAAC


 


301
AATATTGCCG GTATCCGCGT GATTTTGCCG ATTTACCTAC AACAGGCGCG


 


351
GCAGGATAAG ATGTTGGCAC TTTATGCACA AGGGATTTTG GCGCAGGCAG


 


401
AGGGCAGGGT GAAGGAGGCG GTTTCCCATT ACCGGGAATT GATTGCCGCC


 


451
CAACCCGACG CGCCCGCCGT CCGTATGCGT TTGGCGGCGG CATTGTTTGA


 


501
AGACAGGCAG AACGAGGCGG CGGCAGACCA GTTCGACCGC CTGAAAACAG


 


551
AAGATCTGCC GCCGCAGCTT ATGGAGCAGG TCGAGCTGTA CCGCAAGGCA


 


601
TTGCGCGAAC GCGATGCGTG GAAGGTAAAC GGCGGTTTCA GCGTTACCCG


 


651
CGAACACAAT ATCAACCAAG CCCCGAAACA GCAGCAGTAC GGCAATTGGA


 


701
CTTTCCCGAA ACAGGTGGAC GGCACGGCAG TCAATTACCG GTTCGGCGCG


 


751
GAGAAAAAAT GGTCGCTGAA AAACGGCTGG TACACGACGG CGGGCGGCGA


 


801
CGTGTCCGGC AGGGTTTATC CGGGGAATAA GAAATTCAAC GATATGACGG


 


851
CAGGTGTTTC CGGCGGCATC GGTTTTGCCG ACCGGCGTAA AGATGTCGGG


 


901
CTGGCAGTGT TCCACGAACG CCGCACCTAC GGCAACGACG CTTATTCTTA


 


951
CGCCAACGGC GCACGCCTTT ATTTCAACCG TTGGCAAACC CCGAGATGGC


 


1001
AAACGCTGTC TTCGGCGGAG TGGGGGCGTT TGAAGAATAC GCGCCGGGCG


 


1051
CGTTCCGACA ATACCCATTT GCAAATTTCC AATTCGCTGG TGTTTTACCG


 


1101
GAATGCGCGC CAATATTGGA CGGGCGGTTT GGATTTTTAC CGCGAGCGCA


 


1151
ACCCCGCCGA CCGTGGCGAC AATTTCAACC GTTACGGCCT GCGCTTTGCC


 


1201
TGGGGGCAGG AATGGGGCGG CAGCGGCCTG TCTTCGCTGT TCCGCCTCGG


 


1251
CGTGGCGAAA CGGCATTATG AAAAACCCGG CTTCTTCAGC AGTTTTAAAG


 


1301
GGGAAAGGCG CAGGGATAAA GAATCGGACA CATCCTTGAG CCTTTGGCAC


 


1351
CGGGCATTGC ATTTCAAAGG CATCACGCCG CGCCTGACGC TGTCGCACCG


 


1401
CGAAACGTGG AGCAACGATG TGTTTAACGA ATACGAGAAA AACAGGGCGT


 


1451
TTGTCGAGTT TAACAAAACG TTCTGA






This corresponds to the amino acid sequence <SEQ ID 2640: ORF 769.ng>:










g769.pep




1
LIMVIFYFYF CGKTFMPARN RWMLLPLLAS AAYAEETPCE PDLRSRPEFR


 


51
LHEAEVKPID REKVPGQVRE KGKVLQVDGE TLLKNPELLS RAMYSAVVSN


 


101
NIAGIRVILP IYLQQARQDK MLALYAQGIL AQAEGRVKEA VSHYRELIAA


 


151
QPDAPAVRMR LAAALFEDRQ NEAAADQFDR LKTEDLPPQL MEQVELYRKA


 


201
LRERDAWKVN GGFSVTREHN INQAPKQQQY GNWTFPKQVD GTAVNYRFGA


 


251
EKKWSLKNGW YTTAGGDVSG RVYPGNKKFN DMTAGVSGGI GFADRRKDVG


 


301
LAVFHERRTY GNDAYSYANG ARLYFNRWQT PRWQTLSSAE WGRLKNTRRA


 


351
RSDNTHLQIS NSLVFYRNAR QYWTGGLDFY RERNPADRGD NFNRYGLRFA


 


401
WGQEWGGSGL SSLFRLGVAK RHYEKPGFFS SFKGERRRDK ESDTSLSLWH


 


451
RALHFKGITP RLTLSHRETW SNDVFNEYEK NRAFVEFNKT F*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2641>:










m769.seq




1
TTGATAATGG TTATTTTTTA TTTTTGTGGG AAGACATTTA TGCCTGCACG


 


51
AAACAGATGG ATGCTGCTGC TGCCTTTATT GGCAAGCGCG GCATATGCCG


 


101
AAGAAACACC GCGCGAACCG GATTTGAGAA GCCGTCCCGA GTTCAGGCTT


 


151
CATGAAGCGG AGGTCAAACC GATCGACAGG GAGAAGGTGC CGGGGCAGGT


 


201
GCGGGAAAAA GGAAAAGTTT TGCAGATTGA CGGCGAAACC CTGCTGAAAA


 


251
ATCCCGAATT GTTGTCCCGC GCGATGTATT CCGCAGTGGT CTCAAACAAT


 


301
ATTGCCGGTA TCCGCGTTAT TTTGCCGATT TACCTACAAC AGGCGCAGCA


 


351
GGATAAGATG TTGGCACTTT ATGCACAAGG GATTTTGGCG CAGGCAGACG


 


401
GTAGGGTGAA GGAGGCGATT TCCCATTACC GGGAATTGAT TGCCGCCCAA


 


451
CCCGACGCGC CCGCCGTCCG TATGCGTTTG GCGGCAGCAT TGTTTGAAAA


 


501
CAGGCAGAAC GAGGCGGCGG CAGACCAGTT CGACCGCCTG AAGGCGGAAA


 


551
ACCTGCCGCC GCAGCTGATG GAGCAGGTCG AGCTGTACCG CAAGGCATTG


 


601
CGCGAACGCG ATGCGTGGAA GGTAAATGGC GGCTTCAGCG TCACCCGCGA


 


651
ACACAATATC AACCAAGCCC CGAAACGGCA GCAGTACGGC AAATGGACTT


 


701
TCCCGAAACA GGTGGACGGC ACGGCGGTCA ATTACCGGCT CGGCGCGGAG


 


751
AAAAAATGGT CGCTGAAAAA CGGCTGGTAC ACGACGGCGG GCGGCGACGT


 


801
GTCCGGCAGG GTTTATCCGG GGAATAAGAA ATTCAACGAT ATGACGGCAG


 


851
GCGTTTCCGG CGGCATCGGT TTTGCCGACC GGCGCAAAGA TGCCGGGCTG


 


901
GCAGTGTTCC ACGAACGCCG CACCTACGGC AACGACGCTT ATTCTTACAC


 


951
CAACGGCGCA CGCCTTTATT TCAACCGTTG GCAAACCCCG AAATGGCAAA


 


1001
CGTTGTCTTC GGCGGAGTGG GGGCGTTTGA AGAATACGCG CCGGGCGCGT


 


1051
TCCGACAATA CCCATTTGCA AATTTCCAAT TCGCTGGTGT TTTACCGGAA


 


1101
TGCGCGCCAA TATTGGATGG GCGGTTTGGA TTTTTACCGC GAGCGCAACC


 


1151
CCGCCGACCG GGGCGACAAT TTCAACCGTT ACGGCCTGCG CTTTGCCTGG


 


1201
GGGCAGGAAT GGGGCGGCAG CGGCCTGTCT TCGCTGTTGC GCCTCGGCGC


 


1251
GGCGAAACGG CATTATGAAA AACCCGGCTT TTTCAGCGGT TTTAAAGGGG


 


1301
AAAGGCGCAG GGATAAAGAA TTGAACACAT CCTTGAGCCT TTGGCACCGG


 


1351
GCATTGCATT TCAAAGGCAT CACGCCGCGC CTGACGTTGT CGCACCGCGA


 


1401
AACGCGGAGT AACGATGTGT TCAACGAATA CGAGAAAAAT CGGGCGTTTG


 


1451
TCGAGTTTAA TAAAACGTTC TGA






This corresponds to the amino acid sequence <SEQ ID 2642; ORF 769>:










m769.pep




1
LIMVIFYFCG KTFMPARNRW MLLLPLLASA AYAEETPREP DLRSRPEFRL


 


51
HEAEVKPIDR EKVPGQVREK GKVLQIDGET LLKNPELLSR AMYSAVVSNN


 


101
IAGIRVILPI YLQQAQQDKM LALYAQGILA QADGRVKEAI SHYRELIAAQ


 


151
PDAPAVRMRL AAALFENRQN EAAADQFDRL KAENLPPQLM EQVELYRKAL


 


201
RERDAWKVNG GFSVTREHNI NQAPKRQQYG KWTFPKQVDG TAVNYRLGAE


 


251
KKWSLKNGWY TTAGGDVSGR VYPGNKKFND MTAGVSGGIG FADRRKDAGL


 


301
AVFHERRTYG NDAYSYTNGA RLYFNRWQTP KWQTLSSAEW GRLKNTRRAR


 


351
SDNTHLQISN SLVFYRNARQ YWMGGLDFYR ERNPADRGDN FNRYGLRFAW


 


401
GQEWGGSGLS SLLRLGAAKR HYEKPGFFSG FKGERRRDKE LNTSLSLWHR


 


451
ALHFKGITPR LTLSHRETRS NDVFNEYEKN RAFVEFNKTF *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 769 shows 95.1% identity over a 492 aa overlap with a predicted ORF (ORF 769) from N. gonorrhoeae 

m769/g769 95.1% identity in 492 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2643>:










a769.seq




1
TTGATAATGG TTATTTTTTA TTTTTGTGGG AAGACATTTA TGCCTGCACG


 


51
AAACAGATGG ATGCTGCTGC TGCCTTTATT GGCAAGCGCG GCATATGCCG


 


101
AAGAAACACC GCGCGAACCG GATTTGAGAA GCCGTCCCGA GTTCAGGCTT


 


151
CATGAAGCGG AGGTCAAACC AATCGACAGG GAGAAGGTAC CGGGGCAGGT


 


201
GCGGGAAAAA GGAAAAGTTT TGCAGATTGA CGGCGAAACC CTGCTGAAAA


 


251
ATCCCGAATT GCTGTCCCGC GCGATGTATT CCGCAGTGGT CTCAAACAAT


 


301
ATTGCCGGTA TCCGCGTTAT TTTGCCGATT TACCTACAAC AGGCGCAGCA


 


351
GGATAAGATG TTGGCACTTT ATGCACAAGG GATTTTGGCG CAGGCAGACG


 


401
GTAGGGTGAA GGAGGCGATT TCCCATTACC GGGAATTGAT TGTCGCCCAA


 


451
CCCGACGCGC CCGCCGTCCG TATGCGTTTG GCGGCGGCAT TGTTTGAAAA


 


501
CAGGCAGAAC GAGGCGGCGG CAGACCAGTT CGACCGCCTG AAGGCGGAAA


 


551
ACCTGCCGCC GCAGCTGATG GAGCAGGTCG AGCTGTACCG CAAGGCATTG


 


601
CGCGAACGCG ATGCGTGGAA GGTAAATGGC GGCTTCAGCG TTACCCGCGA


 


651
ACACAATATC AACCAAGCCC CGAAACGGCA GCAGTACGGC AAATGGACTT


 


701
TCCCGAAACA GGTGGACGGC ACGGCGGTCA ATTACCGGCT CGGCGCGGAG


 


751
AAAAAATGGT CGCTGAAAAA CGGCTGGTAC ACGACGGCGG GCGGCGACGT


 


801
GTCCGGCAGG GTTTATCCGG GGAATAAGAA ATTCAACGAT ATGACGGCAG


 


851
GCGTTTCCGG CGGCATCGGT TTTGCCGACC GGCGCAAAGA TGCCGGGCTG


 


901
GCAGTGTTCC ACGAACGCCG CACCTACGGC AACGACGCTT ATTCTTACAC


 


951
CAACGGCGCA CGCCTTTATT TCAACCGTTG GCAAACCCCG AAATGGCAAA


 


1001
CGTTGTCTTC GGCGGAGTGG GGGCGTTTGA AGAATACGCG CCGGGCGCGT


 


1051
TCCGACAATA CCCATTTGCA AATTTCCAAT TCGCTGGTGT TTTACCGGAA


 


1101
TGCGCGCCAA TATTGGATGG GCGGTTTGGA TTTTTACCGC GAGCGCAACC


 


1151
CCGCCGACCG GGGCGACAAT TTCAACCGTT ACGGCCTGCG CTTTGCCTGG


 


1201
GGGCAGGAAT GGGGCGGCAG CGGCCTGTCT TCGCTGTTGC GCCTCGGCGC


 


1251
GGCGAAACGG CATTATGAAA AACCCGGCTT TTTCAGCGGT TTTAAAGGGG


 


1301
AAAGGCGCAG GGATAAAGAA TTGAACACAT CCTTGAGCCT TTGGCACCGG


 


1351
GCATTGCATT TCAAAGGCAT CACGCCGCGC CTGACGTTGT CGCACCGCGA


 


1401
AACGCGGAGT AACGATGTGT TCAACGAATA CGAGAAAAAT CGGGCGTTTG


 


1451
TCGAGTTTAA TAAAACGTTC TGA






This corresponds to the amino acid sequence <SEQ ID 2644; ORF 769.a>:










a769.pep




1
LIMVIFYFCG KTFMPARNRW MLLLPLLASA AYAEETPREP DLRSRPEFRL


 


51
HEAEVKPIDR EKVPGQVREK GKVLQIDGET LLKNPELLSR AMYSAVVSNN


 


101
IAGIRVILPI YLQQAQQDKM LALYAQGILA QADGRVKEAI SHYRELIVAQ


 


151
PDAPAVRMRL AAALFENRQN EAAADQFDRL KAENLPPQLM EQVELYRKAL


 


201
RERDAWKVNG GFSVTREHNI NQAPKRQQYG KWTFPKQVDG TAVNYRLGAE


 


251
KKWSLKNGWY TTAGGDVSGR VYPGNKKFND MTAGVSGGIG FADRRKDAGL


 


301
AVFHERRTYG NDAYSYTNGA RLYFNRWQTP KWQTLSSAEW GRLKNTRRAR


 


351
SDNTHLQISN SLVFYRNARQ YWMGGLDFYR ERNPADRGDN FNRYGLRFAW


 


401
GQEWGGSGLS SLLRLGAAKR HYEKPGFFSG FKGERRRDKE LNTSLSLWHR


 


451
ALHFKGITPR LTLSHRETRS NDVFNEYEKN RAFVEFNKTF *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 769 shows 99.8% identity over a 490 aa overlap with a predicted ORF (ORF 769) from N. meningitidis: 

m769/a769 99.8% identity in 490 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2645>:










g770.seq




1
ATGAACAGAC TGCTACTGCT GTCTGCCGCC GTCCTGCCGA CTGCCTGCGG


 


51
CAGCGGCGAA ACCGATAAAA TCGGACGGGC AAGTACCGTT TTCAACATGT


 


101
TGGGCAAAAA CGACCGTATC GAAGTGGAAG GATTCGACGA TCCCGACGTT


 


151
CAAGGGGTTG CCTGTTATAT TTCGTATGCA AAAAAAGGCG GCTTGAAGGA


 


201
AATGGTCAAT TTGGAAGAGG ACGCGTCCGA CGCATCGGTT TCGTGCGTTC


 


251
AGACGGCATC TTCGATTTCT TTTGACGAAA CCGCCGTGCG CAAACCGAAA


 


301
GAAGTTTTCA AGCGCGGTAC GGGCTTCGCG TTCAAGAGCC GGCAGATTGT


 


351
CCGTTATTAC GACCCCAAAC GCAAAGCCTT CGCCTATTTG GTTTACAGCG


 


401
ATAAAATCGT CCAAGGATCG CCGAAAAATT CCTTAAGCGC GGTTTCCTGT


 


451
TTCGGCAGCG GCATACCGCA AACCGACGGG GTGCAAGCCG ATACTTCCGG


 


501
CAAACTGCTT GCCGGCGCCT GCATTATTTC CAACCCGATA AAAAATCCCG


 


551
ACAAACGCTG A






This corresponds to the amino acid sequence <SEQ ID 2646; ORF 770.ng>:










g770.pep




1
MNRLLLLSAA VLPTACGSGE TDKIGRASTV FNMLGKNDRI EVEGFDDPDV


 


51
QGVACYISYA KKGGLKEMVN LEEDASDASV SCVQTASSIS FDETAVRKPK


 


101
EVFKRGTGFA FKSRQIVRYY DPKRKAFAYL VYSDKIVQGS PKNSLSAVSC


 


151
FGSGIPQTDG VQADTSGKLL AGACIISNPI KNPDKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2647>:










m770.seq




1
ATGAACAGAC TGCTACTGCT GTCTGCCGCC GTCCTGCTGA CTGCCTGCGG


 


51
CAGCGGCGAA ACCGATAAAA TCGGACGGGC AAGTACCGTT TTCAACATAC


 


101
TGGGCAAAAA CGACCGTATC GAAGTGGAAG GATTCGACGA TCCCGACGTT


 


151
CAAGGGGTTG CCTGTTATAT TTCGTATGCA AAAAAAGGCG GCTTGAAGGA


 


201
AATGGTCAAT TTGGAAGAGG ACGCGTCCGA CGCATCGGTT TCGTGCGTTC


 


251
AGACGGCATC TTCGATTTCT TTTGACGAAA CCGCCGTGCG CAAACCGAAA


 


301
GAAGTTTTCA AACACGGTGC GAGCTTCGCG TTCAAGAGCC GGCAGATTGT


 


351
CCGTTATTAC GACCCCAAAC GCAAAACCTT CGCCTATTTG GTGTACAGCG


 


401
ATAAAATCAT CCAAGGCTCG CCGAAAAATT CCTTAAGCGC GGTTTCCTGT


 


451
TTCGGCGGCG GCATACCGCA AACCGATGGG GTGCAAGCCG ATACTTCCGG


 


501
CAACCTGCTT GCCGGCGCCT GCATGATTTC CAACCCGATA GAAAATCTCG


 


551
ACAAACGCTG A






This corresponds to the amino acid sequence <SEQ ID 2648; ORF 770>:










m770.pep




1
MNRLLLLSAA VLLTACGSGE TDKIGRASTV FNILGKNDRI EVEGFDDPDV


 


51
QGVACYISYA KKGGLKEMVN LEEDASDASV SCVQTASSIS FDETAVRKPK


 


101
EVFKHGASFA FKSRQIVRYY DPKRKTFAYL VYSDKIIQGS PKNSLSAVSC


 


151
FGGGIPQTDG VQADTSGNLL AGACMISNPI ENLDKR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 770 shows 93.5% identity over a 186 aa overlap with a predicted ORF (ORF 770) from N. gonorrhoeae 

m770/g770 93.5% identity in 186 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2649>:










a770.seq




1
ATGAACAGAC TGCTACTGCT GTCTGCCGCC GTCCTGCTGA CTGCCTGCGG


 


51
CAGCGGCGAA ACCGATAAAA TCGGACGGGC AAGTACCGTT TTCAACATAC


 


101
TGGGCAAAAA CGACCGTATC GAAGTGGAAG GATTCGACGA TCCCGACGTT


 


151
CAAGGGGTTG CCTGTTATAT TTCGTATGCA AAAAAAGGCG GCTTGAAGGA


 


201
AATGGTCAAT TTGGAAGAGG ACGCGTCCGA CGCATCGGTT TCGTGCGTTC


 


251
AGACGGCATC TTCGATTTCT TTTGACGAAA CCGCCGTGCG CAAACCGAAA


 


301
GAAGTTTTCA AACACGGTGC GAGCTTCGCG TTCAAGAGCC GGCAGATTGT


 


351
CCGTTATTAC GACCCCAAAC GCAAAACCTT CGCCTATTTG GTGTACAGCG


 


401
ATAAAATCAT CCAAGGCTCG CCGAAAAATT CCTTAAGCGC GGTTTCCTGT


 


451
TTCGGCGGCG GCATACCGCA AACCGATGGG GTGCAAGCCG ATACTTCCGG


 


501
CAACCTGCTT GCCGGCGCCT GCATGATTTC CAACCCGATA GAAAATCCCG


 


551
ACAAACGCTG A






This corresponds to the amino acid sequence <SEQ ID 2650; ORF 770.a>:










a770.pep




1
MNRLLLLSAA VLLTACGSGE TDKIGRASTV FNILGKNDRI EVEGFDDPDV


 


51
QGVACYISYA KKGGLKEMVN LEEDASDASV SCVQTASSIS FDETAVRKPK


 


101
EVFKHGASFA FKSRQIVRYY DPKRKTFAYL VYSDKIIQGS PKNSLSAVSC


 


151
FGGGIPQTDG VQADTSGNLL AGACMISNPI ENPDKR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 770 shows 99.5% identity over a 186 aa overlap with a predicted ORF (ORF 770) from N. meningitidis: 

m770/a770 99.5% identity in 186 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2651>:










g771.seq




1
ATGGATTTAT TATCGGTTTT CCACAAATAC CGTCTGAAAT ATGCGGTGGC


 


51
GGTGCTGACG ATGCTGCTTT TGGCGGCAGT CGGGCTGCAC GCTTCCGTAT


 


101
ATCGCACCTT CACGCCCGAA AACATCCGCA GCCGCCTCCA ACAAAGCATT


 


151
GCCCATACCC ACCGGAAAAT CTCGTTTGAT GCGGATATAC GGCGCAGGCT


 


201
TCTGCCCCGC CCGACCGTCA TCCTGAAAAA CCTGACCATT ACCGAACCCG


 


251
ACGGCGGCCG GGTCGCCGTT TCCGTCAAAG AAACCAAAAT CGGATTGAGC


 


301
TGGAAAAACC TGTGGTCGGA TCGGATACAG GTTGAAAAAT GGGTGGTTTC


 


351
GGGTGCGGAT CTTGCCCTGA CGCGCGACAG AAACGGCGCT TGGAACATCC


 


401
AAGACCTGTT CGACGGCGCG AAACACTCCG CCTCAGTCAA CCGCATTATC


 


451
GTCGAAAACA GCACCGTCCG CCTCAATTTC CTGCAGCAAC AGCTTATCCT


 


501
GAAGGAAATC AGCCTCAACC TGCAATCCCC CGATTCGTCG GGGCAGCAGT


 


551
TTGAAAGTTC GGGCATACTG GTTTGGAGAA AGCTGTCCGT CCCGTGGAAA


 


601
AGCAGGGGGC TGTTCCTTTC AGACGGCATC GGCACGCCCG AAATCTCACC


 


651
GTTCCATTTT GAAGCTTCCA CTTCGCTGGA CGGACACGGC ATCACCATTT


 


701
CCACCACCGG CAGCCCTTCT GTCCGCTTCA ACGCCGGCGG AGCGGATGCC


 


751
GCCGGCCTCG GCCTGCGTGC AGACACTTCC TTCCGCAACC TCCACCTGAC


 


801
CGCGCAAATC CCCGCACTGG CACTCAAAAA CAACAGCATC AAAACCGGCA


 


851
CGGTCAACGG CACGTTTACC GCCGGCGGCG AATATGCCCG ATGGGACGGT


 


901
TCGTTCAAAC TCGACAAAGC CAACCTGCAC TCCGGCATCG CCAACATCGG


 


951
CAACGCCGAA ATCTCCGGCA GCTTCAAAAC ACCGCGCCTT CAAACCAATT


 


1001
TCTCCCTCGG CTCGCCGTTG GTTTGGAGTC GGGACAACGG GCTGGACGCC


 


1051
CCGCGCCTGC ACATATCGAC CCTTCAGGAT ACCGTCGACC GCCTGCCGCA


 


1101
ACCCCGTTTC ATCAGCCGGC TCGACGGTTC GCTGTCCATA CCGAATCTGC


 


1151
AAAATTGGAA TGCCGAATTA AACGGCACAT TCGACCGCCA ACCCGTTGCC


 


1201
GCAAAATTCA AATATACGCG GGAAGGCGCA CCGCACCTGG AAGCCGCCGC


 


1251
CGCGCTGCAA AAATTAAACC TCGCCCCCTA TCTTGACGAA TTTCGGCAAC


 


1301
AAAACGGCAA AATATTCCCC GACATCCTCG GCAGGCTGTC CGGCAACGTC


 


1351
GAGGCACACC TCAAAATCGG CAGCATCCAA CTCCCCGGCT TGCAACTGGA


 


1401
CGATATGGAA ACCTACCTCC ACGCCGACAA AGACCATATC GCGCTCAGCC


 


1451
GTTTCAAGTC AGGGCTTTAC GGCGGCCATA CCGAAGGCGG CATCAGCATC


 


1501
GCCAACACCC GTCCCGCCAC TTACCGCCTG CAACAGAATG CAAGCAACAT


 


1551
CCAAATCCAA CCGCTGCTGC AAGACCTGTT CGGCTTCCAC AGCTTCAGCG


 


1601
GCAACGGCGA TGCGGTCATC GACCTGACCG CAAGCGGCGA AAACCGCAAA


 


1651
CAGCTTATCC GCTCGCTGCA AGGCAGCCTG TCGCTGAATA TTTCCAACGG


 


1701
CGCGTGGCAC GGCATCGATA TGGACAGCAT TTTAAAAAAC GGCCTTTCCG


 


1751
GGAAAATCTC GGGCAGCACA CCCTTCTACC GATTCACGCT CAACAGCGAA


 


1801
ATTTCAGACG GCATCAGCCG CCACATCGAT ACCGAACTCT TCTCCGACAG


 


1851
CCTCTATGTT ACCAGCAACG GCTATACCAA TCTGGATACG CAGGAATTGT


 


1901
CTGAAGATGT CCTTATCCGC AACGCCGTCC ATCCGAAAAA CAAACCGATT


 


1951
CCCCTGAAAA TCACCGGTAC GGTGGACAAG CCGTCCATTA CCGTCGATTA


 


2001
CGGCAGGCTG ACCGGCGGCA TCAATTCGCG CAAAGAGAAA CAGAAAATCC


 


2051
TCGAAGACAC CCTGCTGGAA CAATGGCAGT GGCTCAAACC TAAAGAACCG


 


3051
TAA






This corresponds to the amino acid sequence <SEQ ID 2652; ORF 771.ng>:










g771.pep




1
MDLLSVFHKY RLKYAVAVLT MLLLAAVGLH ASVYRTFTPE NIRSRLQQSI


 


51
AHTHRKISFD ADIRRRLLPR PTVILKNLTI TEPDGGRVAV SVKETKIGLS


 


101
WKNLWSDRIQ VEKWVVSGAD LALTRDRNGA WNIQDLFDGA KHSASVNRII


 


151
VENSTVRLNF LQQQLILKEI SLNLQSPDSS GQQFESSGIL VWRKLSVPWK


 


201
SRGLFLSDGI GTPEISPFHF EASTSLDGHG ITISTTGSPS VRFNAGGADA


 


251
AGLGLRADTS FRNLHLTAQI PALALKNNSI KTGTVNGTFT AGGEYARWDG


 


301
SFKLDKANLH SGIANIGNAE ISGSFKTPRL QTNFSLGSPL VWSRDNGLDA


 


351
PRLHISTLQD TVDRLPQPRF ISRLDGSLSI PNLQNWNAEL NGTFDRQPVA


 


401
AKFKYTREGA PHLEAAAALQ KLNLAPYLDE FRQQNGKIFP DILGRLSGNV


 


451
EAHLKIGSIQ LPGLQLDDME TYLHADKDHI ALSRFKSGLY GGHTEGGISI


 


501
ANTRPATYRL QQNASNIQIQ PLLQDLFGFH SFSGNGDAVI DLTASGENRK


 


551
QLIRSLQGSL SLNISNGAWH GIDMDSILKN GLSGKISGST PFYRFTLNSE


 


601
ISDGISRHID TELFSDSLYV TSNGYTNLDT QELSEDVLIR NAVHPKNKPI


 


651
PLKITGTVDK PSITVDYGRL TGGINSRKEK QKILEDTLLE QWQWLKPKEP


 


701
*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2653>:










m771.seq




1
ATGGATTTAT TATCGGTTTT CCACAAATAC CGTCTGAAAT ATGCGGTGGC


 


51
CGTGCTGACG ATACTGCTTT TGGCGGCAGT CGGGCTGCAC GCTTCCGTAT


 


101
ATCGCACCTT CACGCCTGAA AACATCCGCA GCCGCCTACA ACAAAGCATT


 


151
GCACACACAC ACCGGAAAAT CTCGTTTGAT GCGGACATTC AGCGCAGGCT


 


201
CCTGCCCCGG CCGACCGTCA TCCTGAAAAA CCTGACCATT ACCGAACCCG


 


251
GCGGCGACCA GACTGCCGTT TCCGTCCAAG AAACCAAAAT CGGATTGAGC


 


301
TGGAAAAACC TGTGGTCGGA TCAGATACAG ATTGAAAAAT GGGTGGTTTC


 


351
GAGTGCGGAA CTTGCCCTGA CGCGCGACGG GAAAGGTGTT TGGAACATCC


 


401
AAGACCTGAT CGACAGCCAA AAACGCCAAG CCTCAGTCAA CCGCATTATC


 


451
GTCGAAAACA GCACCGTCCG CCTCAATTTC CTGCAGGAAC AGCTTATCCT


 


501
GAAGGAAATC AACCTCAACC TGCAATCCCC CGATTCGTCG GGGCAGCCGT


 


551
TTGAAAGTTC GGGCATACTG GTTTGGGGAA AGCTGTCCGT CCCGTGGAAA


 


601
AGCAGGGGGC TGTTCCTTTC AAACGGCATC GGCCCGCCCG AAATCTCACC


 


651
GTTCCATTTT GAAGCTTCCA CTTCGCTGGA CGGACACGGC ATTACCATTT


 


701
CCACCACCGG CAGCCCTTCT GTCCGCTTCA ACGCCGGCGG AGCGGATGCC


 


751
GCCGGCCTCG GCCTGCGTGC AGACACTTCC TTCCGCAACC TCCACCTGAC


 


801
CGCCCAAATC CCCGCGCTGG CACTCAGGAA CAACAGCATT AAAATTGAAA


 


851
CCGTCAACGG CGCATTTACC GCCGGCGGCG AATATGCCCG ATGGGACGGT


 


901
TCGTTCAAAC TCGACAAAGC CAACCTGCAC TCCGGCATCG CCAACATCGG


 


951
CAACGCCGAA ATCTCCGGCA GCTTCAAAAC ACCGCGCCAC CAGACCAACT


 


1001
TCTCCCTCAA TTCGCCGCTC GTATGGACGG AAAACAAAGG GCTGGACGCG


 


1051
CCGCGCCTGT ATGTATCGAC CCTTCAGGAT ACCGTCAACC GCCTGCCGCA


 


1101
ACCCCGTTTC ATCAGCCGGC TCGACGGTTC GCTGTCCGTA CCGAATCTGC


 


1151
AAAATTGGAA TGCCGAATTA AACGGCACAT TCGACCGCCA AACCGTTGCC


 


1201
GCGAAATTCA GATACACACA TGAAGACGCA CCGCATCTGG AAGCCGCCGT


 


1251
CGCACTGCAA AAATTGAACC TGACCCCCTA TCTTGACGAC GTGCGGCAAC


 


1301
AAAACGGCAA AATATTTCCC GACACCCTCG CCAAGCTGTC CGGCGACATC


 


1351
GAGGCGCACC TGAAAATCGG AAAAGTCCAA CTTCCCGGCC TGCAACTGGA


 


1401
CGATATGGAA ACCTACCTCC ACGCCGACAA AGGCCATATC GCGCTCAGCC


 


1451
GTTTCAAGTC AGGGCTTTAC GGCGGCCATA CCGAAGGCGG CATCAGCATC


 


1501
GCCAACACCC GTCCCGCCAC TTACCGCCTG CAACAGAATG CAAGCAACAT


 


1551
CCAAATCCAA CCGCTGCTGC AAGACCTGTT CGGCTTCCAC AGCTTCAGCG


 


1601
GCAACGGCGA CGCGGTCATC GACCTGACCG CGGGCGGCGA AACCCGAAAA


 


1651
GAGCTTATCC GCTCGCTTCA GGGCAGCCTG TCGCTAAATA TTTCCAACGG


 


1701
TGCATGGCAC GGTATCGACA TGGACAATAT CCTGAAAAAC GGCATTTCGG


 


1751
GCAAAACTGC CGACAATGCC GCACCCAGCA CACCCTTCCA CCGATTCACG


 


1801
CTCAACAGCG AAATTTCAGA CGGCATCAGC CGCCACATCG ATACCGAACT


 


1851
CTTCTCCGAC AGCCTCTATG TTACCAGCAA CGGCTATACC AATCTGGATA


 


1901
CGCAGGAATT GTCTGAAGAT GTCCTTATCC GCAACGCCGT CCATCCGAAA


 


1951
AACAAACCGA TTCCCCTGAA AATCACCGGC ACGGTGGACA AACCGTCCAT


 


2001
TACCGTCGAT TACGGCAGGC TGACCGGCGG CATCAATTCG CGCAAAGAGA


 


2051
AACAGAAAAT CCTCGAAGAC ACCCTGCTGG AACAATGGCA GTGGCTCAAA


 


2101
CCTAAAGAAC CGTA






This corresponds to the amino acid sequence <SEQ ID 2654; ORF 771>:










m771.pep




1
MDLLSVFHKY RLKYAVAVLT ILLLAAVGLH ASVYRTFTPE NIRSRLQQSI


 


51
AHTHRKISFD ADIQRRLLPR PTVILKNLTI TEPGGDQTAV SVQETKIGLS


 


101
WKNLWSDQIQ IEKWVVSSAE LALTRDGKGV WNIQDLIDSQ KRQASVNRII


 


151
VENSTVRLNF LQEQLILKEI NLNLQSPDSS GQPFESSGIL VWGKLSVPWK


 


201
SRGLFLSNGI GPPEISPFHF EASTSLDGHG ITISTTGSPS VRFNAGGADA


 


251
AGLGLRADTS FRNLHLTAQI PALALRNNSI KIETVNGAFT AGGEYARWDG


 


301
SFKLDKANLH SGIANIGNAE ISGSFKTPRH QTNFSLNSPL VWTENKGLDA


 


351
PRLYVSTLQD TVNRLPQPRF ISRLDGSLSV PNLQNWNAEL NGTFDRQTVA


 


401
AKFRYTHEDA PHLEAAVALQ KLNLTPYLDD VRQQNGKIFP DTLAKLSGDI


 


451
EAHLKIGKVQ LPGLQLDDME TYLHADKGHI ALSRFKSGLY GGHTEGGISI


 


501
ANTRPATYRL QQNASNIQIQ PLLQDLFGFH SFSGNGDAVI DLTAGGETRK


 


551
ELIRSLQGSL SLNISNGAWH GIDMDNILKN GISGKTADNA APSTPFHRFT


 


601
LNSEISDGIS RHIDTELFSD SLYVTSNGYT NLDTQELSED VLIRNAVHPK


 


651
NKPIPLKITG TVDKPSITVD YGRLTGGINS RKEKQKILED TLLEQWQWLK


 


701
PKEP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 771 shows 90.3% identity over a 704 aa overlap with a predicted ORF (ORF 771) from N. gonorrhoeae 

m771/g771 90.3% identity in 704 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2655>:










a771.seq




1
ATGGATTTAT TATCGGTCTT CCACAAATAC CGTCTGAAAT ATGCGGTAGC


 


51
CGTGCTGACG ATACTGCTTT TGGCGGCAAT CGGGCTGCAC GCTTCCGTAT


 


101
ATCGCATCTT CACACCTGAA AACATCCGAA GCCGCCTCCA ACAAAGCATT


 


151
GCCCATACGC ACCGGAAAAT CTCGTTTGAT GCGGATATAC AGCGCAGGCT


 


201
TCTGCCCCGG CCGACCGTCA TCCTGAAAAA CCTGACCATT ACCGAACCCG


 


251
GCGGCGACCG GACTGCCGTT TCCGTCCAAG AAACCAAAAT CGGATTGAGC


 


301
TGGAAAAACC TGTGGTCGGA TCAGATACAG ATTGAAAAAT GGGTGGTTTC


 


351
GAGTGCGGAA CTTGCCCTGA CGCGCGACGG GAAAGGTGTT TGGAACATCC


 


401
AAGACCTGAT CGACAGCCAA AAACGCCAAG CCTCAGTCAA CCGCATTATC


 


451
GTCGAAAACA GCACCGTCCG CCTCAATTTC CTGCAGGAAC AGCTTATCCT


 


501
GAAGGAAATC AACCTCAACC TGCAATCCCC CGATTCGTCG GGGCAGCCGT


 


551
TTGAAAGTTC GGGCATACTG GTTTGGGGAA AGCTGTCCGT CCCGTGGAAA


 


601
AGCAGGGGGC TGTTCCTTTC AGACGGCATC GGCACGCCCA AAATCTCACC


 


651
GTTCCATTTT GAAGCTTCCA CTTCGCTGGA CGGACACGGC ATTACCATTT


 


701
CCACCACCGG CAGCCCTTCT GTCCGCTTCA ACGCCGGCGG AGCGGATGCC


 


751
GCCGGCCTCG GCCTGCGTGC AGACACTTCC TTCCGCAACC TCCACCTGAC


 


801
CGCCCAAATC CCTACGCTGG CACTCAGGAA CAACAGCATT AAAATTGAAA


 


851
CCGTCAACGG CGCATTTACC GCCGGCGGCG AATATGCCCA ATGGGACGGT


 


901
TCGTTCAAAC TCGACAAAGC CAACCTGCAC TCCGGCATCG CCAACATCGG


 


951
CAACGCCGAA ATCTCCGGCA GCTTCAAAAC ACCGCGCCAC CAGACCAACT


 


1001
TCTCCCTCAA TTCGCCGCTC GTATGGACGG AAAACAAAGG GCTGGACGCG


 


1051
CCGCGCCTGT ATGTATCGAC CCTTCAGGAT ACCGTCAACC GCCTGCCGCA


 


1101
ACCCCGTTTC ATCAGCCGGC TCGACGGTTC GCTGTCCGTA CCGAATCTGC


 


1151
AAAATTGGAA TGCCGAATTA AACGGCACAT TCGACCGCCA AACCGTTGCC


 


1201
GCGAAATTCA GATACACACA TGAAGACGCA CCGCATCTGG AAGCCGCCGT


 


1251
CGCACTGCAA AAATTGAACC TGACCCCCTA TCTTGACGAC GTGCGGCAAC


 


1301
AAAACGGCAA AATATTTCCC GACACCCTCG CCAAGCTGTC CGGCGACATC


 


1351
GAGGCGCACC TGAAAATCGG AAAAGTCCAA CTTCCCGGCC TGCAACTGGA


 


1401
CGATATGGAA ACCTACCTCC ACGCCGACAA AGGCCATATC GCGCTCAGCC


 


1451
GTTTCAAGTC AGGGCTTTAC GGCGGCCATA CCGAAGGCGG CATCAGCATC


 


1501
GCCAACACCC GTCCCGCCAC TTACCGCCTG CAACAGAATG CAAGCAACAT


 


1551
CCAAATCCAA CCGCTGCTGC AAGACCTGTT CGGCTTCCAC AGCTTCAGCG


 


1601
GCAACGGCGA CGCGGTCATC GACCTGACCG CGGGCGGCGA AACCCGAAAA


 


1651
GAGCTTATCC GCTCGCTTCA GGGCAGCCTG TCGCTAAATA TTTCCAACGG


 


1701
TGCATGGCAC GGTATCGACA TGGACAATAT CCTGAAAAAC GGCATTTCGG


 


1751
GCAAAACTGC CGACAATGCC GCACCCAGCA CACCCTTCCA CCGATTCACG


 


1801
CTCAACAGCG AAATTTCAGA CGGCATCAGC CGCCACATCG ATACCGAACT


 


1851
CTTCTCCGAC AGCCTCTATG TTACCAGCAA CGGCTATACC AATCTGGATA


 


1901
CGCAGGAATT GTCTGAAGAT GTCCTTATCC GCAACGCCGT CCATCCGAAA


 


1951
AACAAACCGA TTCCCCTGAA AATCACCGGT ACGGTGGACA AACCGTCCAT


 


2001
TACCGTCGAT TACGGCAGGC TGACCGGCGG CATCAATTCG CGCAAAGAGA


 


2051
AACAGAAAAT CCTCGAAGAC ACCCTGCTGG AACAATGGCA GTGGCTCAAA


 


2101
CCTAAAGAAC CGTAA






This corresponds to the amino acid sequence <SEQ ID 2656; ORF 771.a>:










a771.pep




1
MDLLSVFHKY RLKYAVAVLT ILLLAAIGLH ASVYRIFTPE NIRSRLQQSI


 


51
AHTHRKISFD ADIQRRLLPR PTVILKNLTI TEPGGDRTAV SVQETKIGLS


 


101
WKNLWSDQIQ IEKWVVSSAE LALTRDGKGV WNIQDLIDSQ KRQASVNRII


 


151
VENSTVRLNF LQEQLILKEI NLNLQSPDSS GQPFESSGIL VWGKLSVPWK


 


201
SRGLFLSDGI GTPKISPFHF EASTSLDGHG ITISTTGSPS VRFNAGGADA


 


251
AGLGLRADTS FRNLHLTAQI PTLALRNNSI KIETVNGAFT AGGEYAQWDG


 


301
SFKLDKANLH SGIANIGNAE ISGSFKTPRH QTNFSLNSPL VWTENKGLDA


 


351
PRLYVSTLQD TVNRLPQPRF ISRLDGSLSV PNLQNWNAEL NGTFDRQTVA


 


401
AKFRYTHEDA PHLEAAVALQ KLNLTPYLDD VRQQNGKIFP DTLAKLSGDI


 


451
EAHLKIGKVQ LPGLQLDDME TYLHADKGHI ALSRFKSGLY GGHTEGGISI


 


501
ANTRPATYRL QQNASNIQIQ PLLQDLFGFH SFSGNGDAVI DLTAGGETRK


 


551
ELIRSLQGSL SLNISNGAWH GIDMDNILKN GISGKTADNA APSTPFHRFT


 


601
LNSEISDGIS RHIDTELFSD SLYVTSNGYT NLDTQELSED VLIRNAVHPK


 


651
NKPIPLKITG TVDKPSITVD YGRLTGGINS RKEKQKILED TLLEQWQWLK


 


701
PKEP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 771 shows 98.9% identity over a 704 aa overlap with a predicted ORF (ORF 771) from N. meningitidis

m771/a771 98.9Identity in 704 aa Overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2657>:










g772.seq




1
GTGTTCGGCA CGGTCTTGCG GACTGATGCC GACTGCCTGC AAATCATCGT


 


51
CGTCGGCAAG TTCTTTCAGG TTGTTGCGTA TGGTTTTGCG GCGTTGGCGG


 


101
AAGGCGAGTT TCACCAGTTT GGCGAAATGA TCGAAATCGT CCGCCTTGCC


 


151
GATACGGTGT TTCACCGGAA TCATGCGCAC CACTGCGGAA TCGATTTTCG


 


201
GCGCGGGATC GAACGATTCG GGCGGCACGT CAATCAGCAG CTCCATATCG


 


251
AAAAAATATT GCAGCATCAC ACCCAAGCGA CCGTAGTCGT TGCTTTTCGG


 


301
CGCGGCAACC ATGCGCTCGA CCACTTCTTT TTGCAACATA AAGTGCATAT


 


351
CGGCGACATC GTCCGCCACC TCCGCCAGTT TGAACAAAAG CGGCGTGGAG


 


401
ATGTTATACG GCAGGTTGCC GACGATTTTC TTTTTGCCTG AGATGCCGTT


 


451
GAAATCAAAC TGCAACACGT CGCCTTCGTG AATCACCAGT TTATCCGCAA


 


501
ACGGCAGCGT TTTCAGACGG CATACGATGT CGCGGTCGAT TTCGACAACG


 


551
TGCAGGCGGT TCAGCTTTTT CGCCAAAGGT TCGGTAATTG CCGCCAAACC


 


601
CGGGCCGATT TCAATCACGA CATCATCCGC CTGCGGGCGC ACGGCGTTGA


 


651
CAATATCGCC GATAATCCGC GTGTCCTGCA AAAAATTCTG CCCGAAACGC


 


701
TTGCGGGCTT TGTGTTCTTT CATCGTGTTT CCTCTTCGGT TGAAACCCCG


 


751
CCCTTTAGGG CGGCAGGATC AGACTCTGTT TGGGCGGGGC GTAACCCCTT


 


801
CCAAATCAGG ACGACACATA GGGCGGTGCT TTATGTGTCG TCCTGTGTGT


 


851
TGGAACATAA ATGTGTTTAC AGTATCCGTT TGATGTCGGC ATTGTAA






This corresponds to the amino acid sequence <SEQ ID 2658; ORF 772.ng>:










g772.pep




1
VFGTVLRTDA DCLQIIVVGK FFQVVAYGFA ALAEGEFHQF GEMIEIVRLA


 


51
DTVFHRNHAH HCGIDFRRGI ERFGRHVNQQ LHIEKILQHH TQATVVVAFR


 


101
RGNHALDHFF LQHKVHIGDI VRHLRQFEQK RRGDVIRQVA DDFLFA*DAV


 


151
EIKLQHVAFV NHQFIRKRQR FQTAYDVAVD FDNVQAVQLF RQRFGNCRQT


 


201
RADFNHDIIR LRAHGVDNIA DNPRVLQKIL PETLAGFVFF HRVSSSVETP


 


251
PFRAAGSDSV WAGRNPFQIR TTHRAVLYVS SCVLEHKCVY SIRLMSAL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2659>:










m772.seq




1
ATGTTCGGCG CGGTCTTGCG GATTGATGCC GACTGCCTGC AAATCATCGT


 


51
CGCCTGCAAG CTCTTTCAGA TTGTTGCGTA TGGTTTTGCG GCGTTGGTGG


 


101
AAGGCGAGTT TCACGAGTTT GGCAAAATGC TCGAAATCGT CCGCCTTGCC


 


151
GATGCGGTGT TTCACCGGAA TCATACGGAC GACGGCGGAA TCCACTTTCG


 


201
GCGCAGGGTC GAACGATTCG GGCGGTACGT CAATCAGCAT TTCCATATCG


 


251
AAAAAATATT GCAGCATCAC GCCCAAGCGG CCGTAGTCGT TGCTTTTCGG


 


301
CGCGGCAACC ATACGCTCGA CCACTTCTTT TTGCAGCATA AAGTGCATAT


 


351
CGACGACATC GTCCGCCACC TCCGCCAGCT TGAACAAAAG CGGTGTGGAA


 


401
ATGTTGTACG GGAGGTTGCC GACGATTTTC TTTTTGCCTG CGATGCCGTT


 


451
GAAATCAAAC TGCAATACAT CGCCTTCGTG AATCACCAGT TTATCCGCAA


 


501
ACGGCAGCGT TTTCAGACGG CATACGATGT CGCGGTCGAT TTCGACAACG


 


551
TGCAGGCGGT TCAGCTTTTT CGCCAAAGGT TCGGTAATCG CCGCCAAACC


 


601
CGGGCCGATT TCAATCACGA CATCATCCGC CTGCGGGCGC ACGGCGTTGA


 


651
CAATATCGCT GATAATCCGC GTGTCCTGCA AAAAATTCTG CCCGAAACGC


 


701
TTGCGGGCTT TGTGTTCTTT CATCGTGTTT CCTTTTCGGT TGAAACCCCG


 


751
CCCTTTAGGG CGGTAGAATC AGACTCTATT TGGGAGGGGC GTAACTCTTT


 


801
CCAAATCAGG ATGGCACATA GGGCGGTGCT TTATGTGTCG TCCTGTGTGT


 


851
TGAAACATAA ATGTGTTTAC AGTATCCGTT TGATGTCGGC ATTGTAA






This corresponds to the amino acid sequence <SEQ ID 2660; ORF 772>:










m772.pep




1
MFGAVLRIDA DCLQIIVACK LFQIVAYGFA ALVEGEFHEF GKMLEIVRLA


 


51
DAVFHRNHTD DGGIHFRRRV ERFGRYVNQH FHIEKILQHH AQAAVVVAFR


 


101
RGNHTLDHFF LQHKVHIDDI VRHLRQLEQK RCGNVVREVA DDFLFACDAV


 


151
EIKLQYIAFV NHQFIRKRQR FQTAYDVAVD FDNVQAVQLF RQRFGNRRQT


 


201
RADFNHDIIR LRAHGVDNIA DNPRVLQKIL PETLAGFVFF HRVSFSVETP


 


251
PFRAVESDSI WEGRNSFQIR MAHRAVLYVS SCVLKHKCVY SIRLMSAL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 772 shows 85.2% identity over a 298 aa overlap with a predicted ORF (ORF 772) from N. gonorrhoeae 

m772/g772 85.2% identity in 298 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2661>:










a772.seq




1
ATGTTCGGCG CGGTCTTGCG GATTGATGCC GACTGCCTGC AAATCATCGT


 


51
CGCCTGCAAG CTCTTTCAGA TTGTTGCGTA TGGTTTTGCG GCGTTGGTGG


 


101
AAGGCGAGTT TCACGAGTTT GGCGAAATGC TCGAAATCGT CCGCCTTGCC


 


151
GATACGGTGT TTCACCGGAA TCATGCGGAC GACGGCCGAA TCCACTTTCG


 


201
GCGCGGGGTC GAACGATTCG GGCGGCACGT CAATCAGCAT TTCCATATCG


 


251
AAGAAATATT GCAGCATCAC GCCCAAGCGG CCGTAGTCGT TGCTTTTCGG


 


301
CGCGGCAACC ATACGATCGA CCACTTCTTT TTGCAGCATA AAGTGCATAT


 


351
CGACGACATC GTCCGCCACC TCCGCCAGCT TGAACAAAAG CGGCGTGGAA


 


401
ATGTTGTAGG GCAGGTTGCC GACGATTTTC TTTTTGCCTG CGATGCCGTT


 


451
GAAATCAAAC TGCAATACAT CGCCTTCGTG AATCACCAGT TTATCCGCAA


 


501
ACGGCAGCGT TTTCAGACGG CATACGATGT CGCGGTCGAT TTCGACAACG


 


551
TGCAGGCGGT TCAGCTTTTT CGCCAAAGGT TCGGTAATCG CCGCCAAACC


 


601
CGGACCGATT TCAATCACGA CATCATCCGC CTGCGGGCGC ACGGCGTTGA


 


651
CAATATCGCT GATAATCCGC GTGTCCTGCA AAAAATTCTG CCCGAAACGC


 


701
TTGCGGGCTT TGTGTTCTTT CATCGTGTTT CCTTTTCGGT TGAAACCCCG


 


751
CCCTTTAGGG CGGTAGAATC AGACTCTATT TGGGAGGGGC GTAACTCCTT


 


801
CCAAATCAGG ACGGCACATA GGGCGGTGCT TTATGTGTCG TCCTGTGTGT


 


851
TGAAACATAA ATGTGTTTAC AGTATCCGTT TGATGTCGGC ATTGTAA






This corresponds to the amino acid sequence <SEQ ID 2662; ORF 772.a>:










a772.pep




1
MFGAVLRIDA DCLQIIVACK LFQIVAYGFA ALVEGEFHEF GEMLEIVRLA


 


51
DTVFHRNHAD DGRIHFRRGV ERFGRHVNQH FHIEEILQHH AQAAVVVAFR


 


101
RGNHTIDHFF LQHKVHIDDI VRHLRQLEQK RRGNVVGQVA DDFLFACDAV


 


151
EIKLQYIAFV NHQFIRKRQR FQTAYDVAVD FDNVQAVQLF RQRFGNRRQT


 


201
RTDFNHDIIR LRAHGVDNIA DNPRVLQKIL PETLAGFVFF HRVSFSVETP


 


251
PFRAVESDSI WEGRNSFQIR TAHRAVLYVS SCVLKHKCVY SIRLMSAL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 772 shows 95.6% identity over a 298 aa overlap with a predicted ORF (ORF 772) from N. meningitidis 

m772/a772 95.6% identity in 298 aa overlap





g773.seq not found yet

g773.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2663>:










m773.seq




1
ATGGGATTGG GTGCAACGAC TTTTGTCGGT TCGGGTGCTA TAGGCGGAGG


 


51
TCTGTGCAGT ACCGGGATTG GCTGTGCGGC CGGTGGACTT ATTGCAACGG


 


101
CAGGTATGAC CGGTGGTTAT ACACAGGCCT CAGAAGGAAG CCGGCAATTG


 


151
TTTGGCACTT ACCAGTCCGA TTTTGGTAAA AAAGTTGTCC TATCTTTGGG


 


201
TACACCAATA GAATACGAAT CGCCGTTAGT ATCTGATGCG AAAAATCTAG


 


251
CCGTATGGGG ATTGGAAACG CTGATTACGC GCAAATTGGG AAACTTGGCA


 


301
ACGGGTGTGA AAACTTCCTT GACTCCGAAA ACTGCTGACG TACAGCGAAA


 


351
TATCCTGTCC CAATCCGAAG TCGGTATCAA GTGGGGCAAG GGGATTGAAG


 


401
GACAGGGAAT GCCTTGGGAG GATTATGTCG GTAAGGGCTT GTCTGCCAAT


 


451
GCAAGGTTAC CTAAAAATTT TAAAACATTT GATTATTTTG ATCGTGGTAC


 


501
AGGCACGGCA ATCAGTGCCA AAACTCTGGA TACGCAAACT ACGGCACGCC


 


551
TGTCCAAACC CGAACAGCTT TACAGTACCA TGAAAGGGTA CATCGATAAG


 


601
ACGGCAAATT TCAAAAGTTA TGAATTATCA GAAGTACCGT TAAGGGCAGA


 


651
CATGATCAAA CAGCGCGAAA TCCATCTGGC CATACCCGCA CAAACTAATA


 


701
AGGAGCAAAG ATTGCAGTTG CAACGTGTGG TAGAGTATGG CAAAAGTCAA


 


751
AACATTACAG TCAAAATTAC GGAGATCGAA TAA






This corresponds to the amino acid sequence <SEQ ID 2664; ORF 773>:










m773.pep




1
MGLGATTFVG SGAIGGGLCS TGIGCAAGGL IATAGMTGGY TQASEGSRQL


 


51
FGTYQSDFGK KVVLSLGTPI EYESPLVSDA KNLAVWGLET LITRKLGNLA


 


101
TGVKTSLTPK TADVQRNILS QSEVGIKWGK GIEGQGMPWE DYVGKGLSAN


 


151
ARLPKNFKTF DYFDRGTGTA ISAKTLDTQT TARLSKPEQL YSTMKGYIDK


 


201
TANFKSYELS EVPLRADMIK QREIHLAIPA QTNKEQRLQL QRVVEYGKSQ


 


251
NITVKITEIE *






a773.seq not found yet

a773.pep not found yet

The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2665>:










g774.seq




1
ATGAAGACCA AATTACCGCT TTTTATCATT TGGCTGTCTG TGTCTGCCTC


 


51
CTGTGCTTCC GTTTTACCCG TTCCGGAGGG CAGCCGAACC GAAATGCCGA


 


101
CACAGGAAAA TGCTTCAGAC GGCATTCCCT ATCCCGTTCC CACTCTGCAA


 


151
GACCGTTTGG ACTATCTGGA AGGCAAAATC GTCCGGCTGT CGAACGAAGT


 


201
GGAAATGTTA AACGGGAAAG TCAAAGCATT GGAGCATACG AAAATACACC


 


251
CTTCCGGCAG GACATACGTC CAAAAACTCG ACGACCGCAA ATTGAAAGAG


 


301
CATTACCTCA ATACCGAAGG CGGCAGCGCA TCCGCACATA CCGTCGAAAC


 


351
CGCACAAAAC CTCTACAATC AGGCACTCAA ACACTATCAA AACGGCAGGT


 


401
TTTCTGCCGC AGCCGCCTTG TTGAAGGGGG CGGACGGCGG AGACGGCGGC


 


451
AGCATCGCGC AACGCAGTAT GTACCTGTTG CTGCAAAGCA GGGCGCGTAT


 


501
GGGGAACTGT GAATCTGTCA TCGAAATCGG AGGGCGTTAC GCCAACCGTT


 


551
TCAAAGACAG CCCAACCGCG CCCGAAGTCA TATTCAAAAT CGGCGAATGC


 


601
CAATACAGGC TTCAGCAAAA AGACATTGCA AGGGCGACTT GGCGCAGCCT


 


651
GATACAGACC TATCCCGGCA GCCCGGCGGC AAAACGCGCC GCCGCAGCCG


 


701
TACGCAAACG ATAG






This corresponds to the amino acid sequence <SEQ ID 2666; ORF 774.ng>:










g774.pep




1
MKTKLPLFII WLSVSASCAS VLPVPEGSRT EMPTQENASD GIPYPVPTLQ


 


51
DRLDYLEGKI VRLSNEVEML NGKVKALEHT KIHPSGRTYV QKLDDRKLKE


 


101
HYLNTEGGSA SAHTVETAQN LYNQALKHYQ NGRFSAAAAL LKGADGGDGG


 


151
SIAQRSMYLL LQSRARMGNC ESVIEIGGRY ANRFKDSPTA PEVIFKIGEC


 


201
QYRLQQKDIA RATWRSLIQT YPGSPAAKRA AAAVRKR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2667>:










m774.seq




1
ATGAAGATCA AATTACCGCT TTTTATCATT TGGCTGTCTG TGTCCGCCTC


 


51
CTGTGCTTCC GTTTCACCCG TTCCGGCAGG CAGCCAAACC GAAATGTCGA


 


101
CACGGGAAAA TGCTTCAGAC GGCATTCCCT ATCCCGTTCC GACCTTGCAA


 


151
GACCGTTTGG ACTATCTGGA AGGCAAAATC GTCCGGCTGT CGAACGAAGT


 


201
GGAAACCTTA AACGGCAAAG TCAAAGCACT GGAACACGCA AAAACACATT


 


251
CTTCCGGCAG GGCATACGTC CAAAAACTCG ACGACCGCAA GTTGAAAGAG


 


301
CATTACCTCA ATACCGAAGG CGGCAGCGCA TCCGCACATA CTGTCGAAAC


 


351
CGCACAAAAC CTCTACAATC AGGCACTCAA ACACTATAAA AGCGGCAAGT


 


401
TTTCTGCCGC TGCCTCCCTG TTGAAAGGCG CGGACGGAGG CGACGGCGGC


 


451
AGCATCGCGC AACGCAGTAT GTACCTGTTG CTGCAAAGCA GGGCGCGTAT


 


501
GGGCAACTGC GAATCCGTCA TCGAAATCGG AGGGCGTTAC GCCAACCGTT


 


551
TCAAAGACAG CCCAACCGCG CCTGAAGCCA TGTTCAAAAT CGGCGAATGC


 


601
CAATACAGGC TTCAGCAAAA AGACATTGCA AGGGCGACTT GGCGCAGCCT


 


651
GATACAGACC TATCCCGGCA GCCCGGCGGC AAAACGCGCC GCCGCAGCCG


 


701
TGCGCAAACG ATAG






This corresponds to the amino acid sequence <SEQ ID 2668; ORF 774>:










m774.pep




1
MKIKLPLFII WLSVSASCAS VSPVPAGSQT EMSTRENASD GIPYPVPTLQ


 


51
DRLDYLEGKI VRLSNEVETL NGKVKALEHA KTHSSGRAYV QKLDDRKLKE


 


101
HYLNTEGGSA SAHTVETAQN LYNQALKHYK SGKFSAAASL LKGADGGDGG


 


151
SIAQRSMYLL LQSRARMGNC ESVIEIGGRY ANRFKDSPTA PEAMFKIGEC


 


201
QYRLQQKDIA RATWRSLIQT YPGSPAAKRA AAAVRKR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 774 shows 92.8% identity over a 237 aa overlap with a predicted ORF (ORF 774) from N. gonorrhoeae 

m774/g774 92.8% identity in 237 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2669>:










a774.seq




1
ATGAAGACCA AATTACCGCT TTTTATCATT TGGCTGTCCG TATCCGCCGC


 


51
CTGTTCTTCC CCTGTTTCCC GCAATATTCA GGATATGCGG CTCGAACCGC


 


101
AGGCAGAGGC AGGTAGTTCG GACGCTATTC CCTATCCCGT TCCCACTCTG


 


151
CAAGACCGTT TGGATTATCT GGAAGGCACA CTCGTCCGCC TGTCGAACGA


 


201
AGTGGAAACC TTAAACGGCA AAGTCAAAGC ACTGGAGCAT GCGAAAACAC


 


251
ACCCTTCCAG CAGGGCATAC GTCCAAAAAC TCGACGACCG CAAGTTGAAA


 


301
GAGCATTACC TCAATACCGA AGGCGGCAGC GCATCCGCAC ATACCGTCGA


 


351
AACCGCACAA AACCTCTACA ATCAGGCACT CAAACACTAT AAAAGCGGCA


 


401
GGTTTTCTGC CGCTGCCTCC CTGTTGAAAG GCGCGGACGG AGGCGACGGC


 


451
GGCAGCATCG CGCAACGCAG TATGTACCTG TTGCTGCAAA GCAGGGCGCG


 


501
TATGGGCAAC TGCGAATCCG TCATCGAAAT CGGAGGGCGT TACGCCAACC


 


551
GTTTCAAAGA CAGCCCAACC GCGCCTGAAG CCATGTTCAA AATCGGCGAA


 


601
TGCCAATACA GGCTTCAGCA AAAAGACATT GCAAGGGCGA CTTGGCGCAG


 


651
CCTGATACAG ACCTATCCCG GCAGCCCGGC GGCAAAACGC GCCGCCGCAG


 


701
CCGTGCGCAA ACGATAG






This corresponds to the amino acid sequence <SEQ ID 2670; ORF 774.a>:










a774.pep




1
MKTKLPLFII WLSVSAACSS PVSRNIQDMR LEPQAEAGSS DAIPYPVPTL


 


51
QDRLDYLEGT LVRLSNEVET LNGKVKALEH AKTHPSSRAY VQKLDDRKLK


 


101
EHYLNTEGGS ASAHTVETAQ NLYNQALKHY KSGRFSAAAS LLKGADGGDG


 


151
GSIAQRSMYL LLQSRARMGN CESVIEIGGR YANRFKDSPT APEAMFKIGE


 


201
CQYRLQQKDI ARATWRSLIQ TYPGSPAAKR AAAAVRKR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 774 shows 89.5% identity over a 238 aa overlap with a predicted ORF (ORF 774) from N. meningitidis 

m774/a774 89.5% identity in 238 aa overlap





g790.seq not found yet

g790.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2671>:










m790.seq




1
ATGGCAAGAA GGTCAAAAAC ATTTGAAGAA GCTGCTGCTG AGGTTGAGGA


 


51
ACGTTTCGGT CATCGTGGCA TTAAGTTGGT CGAGTTTGAG GGTACAGCCA


 


101
AGCCGTGTGT AATCAACTGC CCTAAACATG GAAACCAAAC CTGTTCGAGG


 


151
TACTCCAATA TGTTCATAGG AAGTAGCTGG GGTTGCCCCT CTTGTGGTAA


 


201
TGAGCAAGCT GCAAAAGCCG GTATAGCGAC CCTTAGGAAG AATCACATAG


 


251
CGTTAGAAAT GCTGAAACAG GCTGTAACAG GTATGACCAA GCAAGAGCGC


 


301
ATCACGACGC AAGCCTACAA TGAGATGACC AAATCCGTGG CAGGTTCAAA


 


351
CAGCATAGTC CTTAACGATG TCCAAGGCGA TACGACCATC AACAACCATC


 


401
ATACGCATAC GCACAACCAC AGCGATGCCG ATGGCAAAGC ACTGTCGATG


 


451
AGGCTCACAC CCCGTCCTTT GTTGTCAGAC CGTCAGGCGG CGGCTTTCGC


 


501
CCGTACAGGC AAACTCACGG GCAGTTTCGA CCTGTTTGCT TCGGTGgTCG


 


551
CCCCCTCGCA GTACACGTTT GCCGTTGCCA TGCCCGACAC GTCCATGTCG


 


601
CCGGTTATCG AAAAGGGAGA CTTGCTGGTG GTCGAGCCGC GTATGTGCCC


 


651
TGCGGACGAA GACATCGCGC TGATTGAACT GTCCGACAAG CGGCTGGTCG


 


701
TCGCGCACCT TGTTATCGAT ATTGCGGGCA GGATGCTGAT TTATCAGACG


 


751
GGCAGGCCGT CTGAAGCCTT TGACCTGCCC GAAGGCAGCA CGATTTTAGG


 


801
TGTGGTGCTG GAGTCAAAAA ACGGTTTATG TCCGCCGCAC AGGCAAGAAG


 


851
GCGTGTTGAT TCGGATTACC GCCCCTGATG TGTGGACGGT TGGTATGATT


 


901
TCCGCTTCCA AAACGTCGTG TACGCGCCCG ACCGCAGCCC GGAAATCAGC


 


951
CGTATGCTTT CTTCGATTTT GGCAGGCTAC GCGTGGGATA CCGAAAACCC


 


1001
GTTCGTGGCG AAATCCGAAC AACGCCTGA






This corresponds to the amino acid sequence <SEQ ID 2672; ORF 790>:










m790.pep




1
MARRSKTFEE AAAEVEERFG HRGIKLVEFE GTAKPCVINC PKHGNQTCSR


 


51
YSNMFIGSSW GCPSCGNEQA AKAGIATLRK NHIALEMLKQ AVTGMTKQER


 


101
ITTQAYNEMT KSVAGSNSIV LNDVQGDTTI NNHHTHTHNH SDADGKALSM


 


151
RLTPRPLLSD RQAAAFARTG KLTGSFDLFA SVVAPSQYTF AVAMPDTSMS


 


201
PVIEKGDLLV VEPRMCPADE DIALIELSDK RLVVAHLVID IAGRMLIYQT


 


251
GRPSEAFDLP EGSTILGVVL ESKNGLCPPH RQEGVLIRIT APDVWTVGMI


 


301
SASKTSCTRP TAARKSAVCF LRFWQATRGI PKTRSWRNPN NA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2673>:










a790.seq




1
ATGGCAAGAA GGTCAAAAAC ATTTGAAGAA GCTGCTGCTG AGGTTGAGGA


 


51
ACGTTTCGGT CATCGTGGCA TTAAGTTGGT CGAGTTTGAG GGTACAGCCA


 


101
AGCCGTGTGT AATCAACTGC CCTAAACATG GAAACCAAAC CTGTTCGAGG


 


151
TACTCCAATA TGTTCATAGG AAGTAGCTGG GGTTGCCCCT CTTGTGGTAA


 


201
TGAGCAAGCT GCAAAAGCCG GTATAGCGAC CCTTAGGAAG AATCACATAG


 


251
CGTTAGAAAT GCTGAAACAG GCTGTAACAG GTATGACCAA GCAAGAGCGC


 


301
ATCACGACGC AAGCCTACAA TGAGATGACC AAATCCGTGG CAGGTTCAAA


 


351
CAGCATAATC CTTAACGATG TCCAAGGCGA TACGACCATC AACAACCATC


 


401
ATACGCATAC GCACAACCAC AGCGATGCCG ACGGCAAAGC ACTGTCGATG


 


451
AGGCTCACAC CCCGTCCTTT GTTGTCAGAC CGTCAGGCGG CGGCTTTCGC


 


501
CCGTACAGGC AAACTCACGG GCAGTTTCGA CCTGTTTGCT TCGGTGGTCG


 


551
CCCCTTCACA ATATACGTTT GCCGTTGCCA TGCCCGACAC GTCCATGTCG


 


601
CCGGTTATCG AAAAGGGGGA TTTGCTGGTG GTCGAGCCGC GTATGCGCCC


 


651
TGCGGACGAA GACATCGTAC TGATTGAACT GTCCGACAAG CGGCTGGTCG


 


701
TCGCGCACCT TGTTATCGAT ATTGCGGGCA GGATGCTGAT TTATCAGACG


 


751
GGCAGGCCGT CTGAAGCCCT CGACCTGCCC GAAGGCAGCG TGATTTTAGG


 


801
TGTGGTGCTG GAGTCAAAAA ACGGTTTATG TCCGCCGCAC AGGCAAGAAG


 


851
GCGTGTTGAT TCGGATTACC GCCCCTGATG TGTGGACGGT TGGTACGATT


 


901
TCCGCTTCCA AAACGTCGTG TACGCGCCCG ACCGCAGCCC GGAAATCAGC


 


951
CGTATGCTTT CTTCGATTTT GGCAGGCTAC GCGTGGGATA CCGAAAACCC


 


1001
GTTCGTGGCG AAATCCGAAC AACGCCTGT






This corresponds to the amino acid sequence <SEQ ID 2674; ORF 790.a>:










a790.pep




1
MARRSKTFEE AAAEVEERFG HRGIKLVEFE GTAKPCVINC PKHGNQTCSR


 


51
YSNMFIGSSW GCPSCGNEQA AKAGIATLRK NHIALEMLKQ AVTGMTKQER


 


101
ITTQAYNEMT KSVAGSNSII LNDVQGDTTI NNHHTHTHNH SDADGKALSM


 


151
RLTPRPLLSD RQAAAFARTG KLTGSFDLFA SVVAPSQYTF AVAMPDTSMS


 


201
PVIEKGDLLV VEPRMRPADE DIVLIELSDK RLVVAHLVID IAGRMLIYQT


 


251
GRPSEALDLP EGSVILGVVL ESKNGLCPPH RQEGVLIRIT APDVWTVGTI


 


301
SASKTSCTRP TAARKSAVCF LRFWQATRGI PKTRSWRNPN NAC






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 790 shows 98.2% identity over a 342 aa overlap with a predicted ORF (ORF 790) from N. meningitidis 

a790/m790 98.2% identity in 342 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2675>:










g791.seq




1
ATGGTAAATT ATTATTCAGC TATGATTAAA AAGATTTTAA CTACTTGTTT


 


51
TGGTTTGTTT TTTGGTTTTT GTGTATTTGG AGTGGGTCTG GTTGCCATTG


 


101
CTATTTTGGT AACGTATCCG AAACTGCCGT CTTTGGATTC TTTGCAGCAT


 


151
TACCAGCCTA AAATGCCGTT GACTATTTAT TCGGCGGATG GAGAAGTCAT


 


201
CGGTATGTAT GGGGAGCAGC GGCGCGAATT TACAAAAATC GGCGATTTCC


 


251
CCGAGGTGTT GCGGAATGCG GTTATTGCCG CCGAGGATAA ACGCTTTTAC


 


301
CGGCATTGGG GGGTGGATGT TTGGGGTGTT GCCCGCGCTG CCGTCGGCAA


 


351
TGTCGTGTCC GGCAGCGTGC AGTCGGGTGC GAGTACGATT ACACAGCAGG


 


401
TGGCGAAAAA TTTTTATTTG AGCAGTGAAA AAACGTTCAC ACGCAAATTC


 


451
AATGAGGTGT TGCTTGCCTA TAAAATCGAG CAGTCTTTAA GCAAAGACAA


 


501
AATCCTTGAG TTGTATTTCA ATCAGATTTA CCTCGGTCAG CGCGCCTATG


 


551
GTTTTGCATC TGCCGCGCAA ATCTATTTCA ATAAGAATGT CCGAGATTTG


 


601
ACTTTGGCGG AAGCCGCCAT GCTTGCGGGA CTGCCCAAGG CTCCGTCTGC


 


651
CTATAATCCG ATTGTTAATC CGGAGCGTGC CAAGTTGCGC CAGAAGTATA


 


701
TTTTGAACAA TATGCTCGAG GAGAAGATGA TTACCGTGCA ACAGCGCGAT


 


751
CAGGCATTGA ATGAGGAACT GCATTATGAG CGGTTTGTTC GGAAAATCGA


 


801
TCAGAGTGCT TTATATGTGG CGGAAATGGT GCGTCGGGAA CTGTATGAGA


 


851
AATATGGTGA AGATGCCTAT ACGCAGGGTT TTAAGGTTTA TACCACGGTC


 


901
CGCACCGATC ATCAGAAGGC GGCAACCGAG GCATTGCGCA AGGCTCTACG


 


951
GAATTTCGAT CGCGGCAGCA GCTACCGCGG TGCGGAAAAC TATATCGATT


 


1001
TGAGTAAGAG TGAAGATGTC GAGGAGACTG TCAGCCAGTA TCTGTCGGGA


 


1051
CTCTATACCG TCGATAAAAT GGTTCCCGCC GTTGTGTTGG ATGTTACTAA


 


1101
AAAGAAAAAT GTCGTCATAC AGCTGCCCGG CGGCAGGCGG GTTGCGCTTG


 


1151
ACAGGCGCGC CTTGGGTTTT GCGGCCCGAG CGGTCGATAA TGAGAAAATG


 


1201
GGGGAGGACC GTATCCGCAG GGGCGCGGTC ATCCGTGTCA AAAACAACGG


 


1251
CGGGCGTTGG GCGGTGGTTC AAGAGCCGTT GCTGCAGGGG GCTTTGGTTT


 


1301
CGCTGGATGC AAAAACCGGA GCTGTGCGCG CGCTGGTCGG CGGTTATGAT


 


1351
TTTCACAGCA AAACATTCAA TCGTGCCGTT CAGGCAATGC GGCAGCCGGG


 


1401
TTCGACCTTT AAGCCGTTTG TCTATTCGGC GGCATTATCT AAGGGGATGA


 


1451
CCGCGTCCAC AGTGGTTAAC GATGCGCCGA TTTCCCTGCC GGGGAAAGGG


 


1501
CCGAACGGTT CGGTTTGGAC ACCTAAAAAT TCAGACGGCA GATATTCCGG


 


1551
CTACATTACT TTGAGACAGG CTCTGACGGC TTCCAAGAAT ATGGTTTCCA


 


1601
TCCGTATTTT GATGTCTATC GGTGTCGGTT ACGCGCAACA GTATATCCGG


 


1651
CGTTTCGGCT TCAGGCCGTC CGAGCTGCCG GCAAGCCTGT CTATGGCTTT


 


1701
AGGTACGGGC GAGACGACGC CGTTGAAAGT GGCGGAGGCA TATAGTGTAT


 


1751
TTGCGAACGG CGGATATAGG GTTTCTTCGC ACGTGATCGA TAAGATTTAT


 


1801
GACAGAGACG GCAGGTTGCG CGCCCAAATG CAACCTTTGG TGGCAGGGCA


 


1851
AAATGCGCCT CAGGCAATCG ATCCGCGCAA TGCCTATATT ATGTATAAGA


 


1901
TTATGCAGGA TGTGGTCCGT GTCGGTACGG CAAGGGGGGC AGCTGCGTTG


 


1951
GGAAGAACGG ATATTGCCGG TAAAACGGGT ACGACCAACG ACAATAAAGA


 


2001
TGCGTGGTTT GTCGGTTTTA ACCCTGATGT GGTTACTGCC GTATATATCG


 


2051
GCTTCGACAA ACCTAAGAGT ATGGGGCGTG CCGGCTACGG CGGTACGATT


 


2101
GCGGTGCCGG TTTGGGTGGA CTATATGCGT TTTGCGTTGA AAGGAAAGCA


 


2151
GGGCAAAGGG ATGAAAATGC CTGAAGGTGT GGTCAGCAGC AATGGCGAAT


 


2201
ACTATATGAA GGAACGTATG GTAACCGATC CGGGCTTGAT GCTGGACAAC


 


2251
AGCGGTATTG CGCCGCAACC TTCCCGACGG GCAAAAGAAG ATGATGAAGC


 


2301
GGCAGTAGAA AACGAACAGC AGGGAAGGTC TGACGAAACG CGTCAGGACG


 


2351
TACAGGAAAC GCCGGTGCTT CCGAGCAATA CGGATTCCAA ACAGCAGCAG


 


2401
TTGGATTCCC TGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2676; ORF 791.ng>:










g791.pep




1
MVNYYSAMIK KILTTCFGLF FGFCVFGVGL VAIAILVTYP KLPSLDSLQH


 


51
YQPKMPLTIY SADGEVIGMY GEQRREFTKI GDFPEVLRNA VIAAEDKRFY


 


101
RHWGVDVWGV ARAAVGNVVS GSVQSGASTI TQQVAKNFYL SSEKTFTRKF


 


151
NEVLLAYKIE QSLSKDKILE LYFNQIYLGQ RAYGFASAAQ IYFNKNVRDL


 


201
TLAEAAMLAG LPKAPSAYNP IVNPERAKLR QKYILNNMLE EKMITVQQRD


 


251
QALNEELHYE RFVRKIDQSA LYVAEMVRRE LYEKYGEDAY TQGFKVYTTV


 


301
RTDHQKAATE ALRKALRNFD RGSSYRGAEN YIDLSKSEDV EETVSQYLSG


 


351
LYTVDKMVPA VVLDVTKKKN VVIQLPGGRR VALDRRALGF AARAVDNEKM


 


401
GEDRIRRGAV IRVKNNGGRW AVVQEPLLQG ALVSLDAKTG AVRALVGGYD


 


451
FHSKTFNRAV QAMRQPGSTF KPFVYSAALS KGMTASTVVN DAPISLPGKG


 


501
PNGSVWTPKN SDGRYSGYIT LRQALTASKN MVSIRILMSI GVGYAQQYIR


 


551
RFGFRPSELP ASLSMALGTG ETTPLKVAEA YSVFANGGYR VSSHVIDKIY


 


601
DRDGRLRAQM QPLVAGQNAP QAIDPRNAYI MYKIMQDVVR VGTARGAAAL


 


651
GRTDIAGKTG TTNDNKDAWF VGFNPDVVTA VYIGFDKPKS MGRAGYGGTI


 


701
AVPVWVDYMR FALKGKQGKG MKMPEGVVSS NGEYYMKERM VTDPGLMLDN


 


751
SGIAPQPSRR AKEDDEAAVE NEQQGRSDET RQDVQETPVL PSNTDSKQQQ


 


801
LDSLF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2677>:










m791.seq




1
ATGGTAAATT ATTATTCAGC TATGATTAAA AAGATTTTAA CGACTTGTTT



 


51
TGGTTTGGTT TTTGGGTTTT GTGTATTTGG AGTGGGTTTG GTTGCCATTG


 


101
CTATTTTGGT AACGTATCCG AAACTGCCGT CTTTGGATTC TTTGCAGCAT


 


151
TACCAGCCTA AAATGCCGTT GACTATTTAT TCGGCGGATG GGGAAGTCAT


 


201
CGGTATGTAT GGGGAGCAGC GGCGCGAATT TACAAAAATC GGCGATTTCC


 


251
CAGAGGTGTT GCGGAATGCG GTTATCGCCG CCGAGGATAA ACGCTTTTAC


 


301
CGGCATTGGG GGGTGGATGT TTGGGGTGTT GCCCGCGCTG CCGTCGGCAA


 


351
TGTCGTGTCC GGCAGCGTGC AGTCGGGTGC GAGTACGATT ACGCAGCAGG


 


401
TGGCGAAAAA TTTTTATTTG AGCAGTGAAA AAACGTTCAC ACGCAAATTC


 


451
AATGAGGTGT TGCTTGCCTA TAAAATCGAG CAGTCTTTAA GCAAAGACAA


 


501
AATCCTCGAG TTGTATTTCA ATCAGATTTA CCTCGGTCAG CGCGCCTATG


 


551
GTTTTGCATC TGCCGCGCAA ATCTATTTCA ATAAGAATGT CCGAGATTTG


 


601
ACTTTGGCGG AAGCCGCCAT GCTTGCGGGA CTGCCCAAGG CTCCGTCTGC


 


651
CTATAATCCG ATTGTTAATC CAGAACGTGC CAAGTTGCGC CAGAAGTATA


 


701
TTTTGAACAA TATGCTCGAG GAGAAGATGA TTACCGTGCA ACAGCGCGAT


 


751
CAGGCGTTGA ATGAGGAACT GCATTACGAG CGGTTTGTTC GGAAAATCGA


 


801
TCAGAGTGCG TTATATGTGG CGGAAATGGT GCGTCAGGAA CTGTATGAGA


 


851
AATACGGTGA AGATGCCTAT ACGCAGGGTT TTAAGGTTTA TACCACGGTC


 


901
CGCGCCGATC ATCAGAAGGT GGCAACCGAG GCATTGCGCA AGGCTCTACG


 


951
GAATTTCGAT CGCGGCAGCA GCTACCGCGG TGCGGAAAAC TATATCGATT


 


1001
TGAGTAAGAG TGAAGATGTC GAGGAGACTG TCAGCCAGTA TCTGTCGGGA


 


1051
CTCTATACCG TCGATAAAAT GGTTCCCGCC GTTGTGTTGG ATGTGACTAA


 


1101
AAAGAAAAAT GTCGTCATAC AGCTGCCCGG CGGCAGGCGG GTTACGCTTG


 


1151
ACAGGCGCGC CTTGGGTTTT GCGGCCCGCG CGGTCAATAA TGAAAAAATG


 


1201
GGGGAGGACC GTATCCGCAG GGGCGCGGTC ATCCGTGTCA AAAACAACGG


 


1251
CGGGCGTTGG GCGGTGGTTC AAGAGCCGTT GCTGCAGGGG GCTTTGGGTT


 


1301
CGCTGGATGC AAAAACCGGA GCTGTGCGCG CGCTGGTCGG CGGTTATGAT


 


1351
TTTCACAGCA AAACATTCAA TCGTGCCGTT CAGGCAATGC GGCAGCCGGG


 


1401
TTCGACCTTT AAGCCGTTTG TCTATTCGGC GGCATTATCT AAGGGGATGA


 


1451
CCGCGTCCAC AGTGGTTAAC GATGCGCCGA TTTCCCTGCC GGGGAAAGGG


 


1501
CCGAACGGTT CGGTTTGGAC ACCTAAAAAT TCAGACGGCA GATATTCCGG


 


1551
CTACATTACT TTGAGACAGG CTCTGACGGC TTCCAAGAAT ATGGTTTCCA


 


1601
TCCGTATTTT GATGTCTATC GGTGTCGGTT ACGCGCAACA GTATATCCGG


 


1651
CGTTTCGGCT TCAGGTCGTC CGAGCTGCCG GCAAGCCTGT CTATGGCTTT


 


1701
AGGTACGGGC GAGACAACGC CGTTGAAAGT GGCGGAGGCA TATAGCGTAT


 


1751
TTGCGAACGG CGGATATAGG GTTTCTTCGC ACGTAATCGA TAAGATTTAT


 


1801
GACAGAGACG GCAGGTTGCG CGCCCAAATG CAACCTTTGG TGGCTGGGCA


 


1851
AAATGCGCCT CAGGCAATCG ATCCGCGCAA TGCCTATATT ATGTATAAGA


 


1901
TTATGCAGGA TGTGGTCCGT GTTGGTACGG CAAGGGGGGC AGCTGCGTTG


 


1951
GGAAGAACGG ATATTGCCGG TAAAACGGGT ACGACCAATG ACAATAAGGA


 


2001
TGCGTGGTTT GTCGGTTTTA ACCCTGATGT GGTTACTGCC GTATATATCG


 


2051
GCTTCGACAA ACCTAAGAGT ATGGGGCGTG TCGGCTACGG CGGTACGATT


 


2101
GCGGTGCCGG TTTGGGTGGA CTATATGCGT TTTGCGTTGA AAGGAAAGCA


 


2151
GGGCAAGGGG ATGAAAATGC CTGAAGGTGT GGTCAGCAGC AATGGCGAAT


 


2201
ACTATATGAA GGAACGTATG GTAACCGATC CGGGCTTGAC GCTGGACAAC


 


2251
AGCGGTATTG CGCCGCAACC TTCCCGACGG GCAAAAGAAG ATGACGGGGG


 


2301
CGCGGCAGAA GGCGGACGGC AGGCGGCGGA TGACGAAGTC CGCCAAGATA


 


2351
TGCAGGAAAC GCCGGTGCTT CCGAGTAATA CTGGTTCCAA ACAGCAGCAG


 


2401
TTGGATTCTC TGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2678; ORF 791>:










m791.pep




1
MVNYYSAMIK KILTTCFGLV FGFCVFGVGL VAIAILVTYP KLPSLDSLQH



 


51
YQPKMPLTIY SADGEVIGMY GEQRREFTKI GDFPEVLRNA VIAAEDKRFY


 


101
RHWGVDVWGV ARAAVGNVVS GSVQSGASTI TQQVAKNFYL SSEKTFTRKF


 


151
NEVLLAYKIE QSLSKDKILE LYFNQIYLGQ RAYGFASAAQ IYFNKNVRDL


 


201
TLAEAAMLAG LPKAPSAYNP IVNPERAKLR QKYILNNMLE EKMITVQQRD


 


251
QALNEELHYE RFVRKIDQSA LYVAEMVRQE LYEKYGEDAY TQGFKVYTTV


 


301
RADHQKVATE ALRKALRNFD RGSSYRGAEN YIDLSKSEDV EETVSQYLSG


 


351
LYTVDKMVPA VVLDVTKKKN VVIQLPGGRR VTLDRRALGF AARAVNNEKM


 


401
GEDRIRRGAV IRVKNNGGRW AVVQEPLLQG ALGSLDAKTG AVRALVGGYD


 


451
FHSKTFNRAV QAMRQPGSTF KPFVYSAALS KGMTASTVVN DAPISLPGKG


 


501
PNGSVWTPKN SDGRYSGYIT LRQALTASKN MVSIRILMSI GVGYAQQYIR


 


551
RFGFRSSELP ASLSMALGTG ETTPLKVAEA YSVFANGGYR VSSHVIDKIY


 


601
DRDGRLRAQM QPLVAGQNAP QAIDPRNAYI MYKIMQDVVR VGTARGAAAL


 


651
GRTDIAGKTG TTNDNKDAWF VGFNPDVVTA VYIGFDKPKS MGRVGYGGTI


 


701
AVPVWVDYMR FALKGKQGKG MKMPEGVVSS NGEYYMKERM VTDPGLTLDN


 


751
SGIAPQPSRR AKEDDGGAAE GGRQAADDEV RQDMQETPVL PSNTGSKQQQ


 


801
LDSLF*






g791/m791 97.3% identity in 805 aa overlap








The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2679>:










a791.seq




1
ATGGTAAATT ATTATTCAGC TATGATTAAA AAGATTTTAA CGACTTGTTT



 


51
TGGTTTGGTT TTTGGGTTTT GTGTATTTGG AGTGGGTTTG GTTGCCATTG


 


101
CTATTTTGGT AACGTATCCG AAACTGCCGT CTTTGGATTC TTTGCAGCAT


 


151
TACCAGCCTA AAATGCCGTT GACTATTTAT TCGGCGGATG GGGAAGTCAT


 


201
CGGTATGTAT GGGGAGCAGC GGCGCGAATT TACAAAAATC GGCGATTTCC


 


251
CAGAGGTGTT GCGGAATGCG GTTATCGCCG CCGAGGATAA ACGCTTTTAC


 


301
CGGCATTGGG GGGTGGATGT TTGGGGTGTT GCCCGCGCTG CCGTCGGCAA


 


351
TGTCGTGTCC GGCAGCGTGC AGTCGGGTGC GAGTACGATT ACGCAGCAGG


 


401
TGGCGAAAAA TTTTTATTTG AGCAGTGAAA AAACGTTCAC ACGCAAATTC


 


451
AATGAGGTGT TGCTTGCCTA TAAAATCGAG CAGTCTTTAA GCAAAGACAA


 


501
AATCCTCGAG TTGTATTTCA ATCAGATTTA CCTCGGTCAG CGCGCCTATG


 


551
GTTTTGCATC TGCCGCGCAA ATCTATTTCA ATAAGAATGT CCGAGATTTG


 


601
ACTTTGGCGG AAGCCGCCAT GCTTGCGGGA CTGCCCAAGG CTCCGTCTGC


 


651
CTATAATCCG ATTGTTAATC CAGAACGTGC CAAGTTGCGC CAGAAGTATA


 


701
TTTTGAACAA TATGCTCGAG GAGAAGATGA TTACCGTGCA ACAGCGCGAT


 


751
CAGGCGTTGA ATGAGGAACT GCATTACGAG CGGTTTGTTC GGAAAATCGA


 


801
TCAGAGTGCT TTATATGTGG CGGAAATGGT GCGTCAGGAA CTGTATGAGA


 


851
AATACGGTGA AGATGCCTAT ACGCAGGGTT TTAAGGTTTA TACCACGGTC


 


901
CGCGCCGATC ATCAGAAGGT GGCAACCGAG GCATTGCGCA AGGCTCTACG


 


951
GAATTTCGAT CGCGGCAGCA GCTACCGCGG TGCGGAAAAC TATATCGATT


 


1001
TGAGTAAGAG TGAAGATGTC GAGGAGACTG TCAGCCAGTA TCTGTCGGGA


 


1051
CTCTATACCG TCGATAAAAT GGTTCCCGCC GTTGTGTTGG ATGTGACTAA


 


1101
AAAGAAAAAT GTCGTCATAC AGCTGCCCGG CGGCAGGCGG GTTACGCTTG


 


1151
ACAGGCGCGC CTTGGGTTTT GCGGCCCGCG CGGTCAATAA TGAAAAAATG


 


1201
GGGGAGGACC GTATCCGCAG GGGCGCGGTC ATCCGTGTCA AAAACAACGG


 


1251
CGGGCGTTGG GCGGTGGTTC AAGAGCCGTT GCTGCAGGGG GCTTTGGTTT


 


1301
CGCTGGATGC AAAAACCGGA GCTGTGCGCG CGCTGGTCGG CGGTTATGAT


 


1351
TTTCACAGCA AAACATTCAA TCGTGCCGTT CAGGCAATGC GGCAGCCGGG


 


1401
TTCGACCTTT AAGCCGTTTG TCTATTCGGC GGCATTATCT AAGGGGATGA


 


1451
CCGCGTCCAC AGTGGTTAAC GATGCGCCGA TTTCCCTGCC GGGGAAAGGG


 


1501
CCGAACGGTT CGGTTTGGAC ACCTAAAAAT TCAGACGGCA GATATTCCGG


 


1551
CTACATTACT TTGAGACAGG CTCTGACGGC TTCCAAGAAT ATGGTTTCCA


 


1601
TCCGTATTTT GATGTCTATC GGTGTCGGTT ACGCGCAACA GTATATCCGG


 


1651
CGTTTCGGCT TCAGGTCGTC CGAGCTGCCG GCAAGCCTGT CTATGGCTTT


 


1701
AGGTACGGGC GAGACAACGC CGTTGAAAGT GGCGGAGGCA TATAGCGTAT


 


1751
TTGCGAACGG CGGATATAGG GTTTCTTCGC ACGTAATCGA TAAGATTTAT


 


1801
GACAGAGACG GCAGGTTGCG CGCCCAAATG CAACCTTTGG TGGCCGGGCA


 


1851
AAATGCGCCT CAGGCAATCG ATCCGCGCAA TGCCTATATT ATGTATAAGA


 


1901
TTATGCAGGA TGTGGTCCGT GTTGGTACGG CAAGGGGGGC AGCTGCGTTG


 


1951
GGAAGAACGG ATATTGCCGG TAAAACGGGT ACGACCAATG ACAATAAGGA


 


2001
TGCGTGGTTT GTCGGTTTTA ACCCTGATGT GGTTACTGCC GTATATATCG


 


2051
GCTTCGACAA ACCTAAGAGT ATGGGGCGTG TCGGCTACGG CGGTACGATT


 


2101
GCGGTGCCGG TTTGGGTGGA CTATATGCGT TTTGCGTTGA AAGGAAAGCA


 


2151
GGGCAAGGGG ATGAAAATGC CTGAAGGTGT GGTCAGCAGC AATGGCGAAT


 


2201
ACTATATGAA GGAACGTATG GTAACCGATC CGGGCTTGAC GCTGGACAAC


 


2251
AGCGGTATTG CGCCGCAACC TTCCCGACGG GCAAAAGAAG ATGACGGGGG


 


2301
CGCGGCAGAA GGCGGACGGC AGGCGGCGGA TGACGAAGTC CGCCAAGATA


 


2351
TGCAGGAAAC GCCGGTGCTT CCGAGTAATA CTGGTTCCAA ACAGCAGCAG


 


2401
TTGGATTCTC TGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2680; ORF 791.a>:










a791.pep




1
MVNYYSAMIK KILTTCFGLV FGFCVFGVGL VAIAILVTYP KLPSLDSLQH



 


51
YQPKMPLTIY SADGEVIGMY GEQRREFTKI GDFPEVLRNA VIAAEDKRFY


 


101
RHWGVDVWGV ARAAVGNVVS GSVQSGASTI TQQVAKNFYL SSEKTFTRKF


 


151
NEVLLAYKIE QSLSKDKILE LYFNQIYLGQ RAYGFASAAQ IYFNKNVRDL


 


201
TLAEAAMLAG LPKAPSAYNP IVNPERAKLR QKYILNNMLE EKMITVQQRD


 


251
QALNEELHYE RFVRKIDQSA LYVAEMVRQE LYEKYGEDAY TQGFKVYTTV


 


301
RADHQKVATE ALRKALRNFD RGSSYRGAEN YIDLSKSEDV EETVSQYLSG


 


351
LYTVDKMVPA VVLDVTKKKN VVIQLPGGRR VTLDRRALGF AARAVNNEKM


 


401
GEDRIRRGAV IRVKNNGGRW AVVQEPLLQG ALVSLDAKTG AVRALVGGYD


 


451
FHSKTFNRAV QAMRQPGSTF KPFVYSAALS KGMTASTVVN DAPISLPGKG


 


501
PNGSVWTPKN SDGRYSGYIT LRQALTASKN MVSIRILMSI GVGYAQQYIR


 


551
RFGFRSSELP ASLSMALGTG ETTPLKVAEA YSVFANGGYR VSSHVIDKIY


 


601
DRDGRLRAQM QPLVAGQNAP QAIDPRNAYI MYKIMQDVVR VGTARGAAAL


 


651
GRTDIAGKTG TTNDNKDAWF VGFNPDVVTA VYIGFDKPKS MGRVGYGGTI


 


701
AVPVWVDYMR FALKGKQGKG MKMPEGVVSS NGEYYMKERM VTDPGLTLDN


 


751
SGIAPQPSRR AKEDDGGAAE GGRQAADDEV RQDMQETPVL PSNTGSKQQQ


 


801
LDSLF*






a791/m791 99.9% identity in 805 aa overlap








The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2681>:










g792.seq




1
ATGTTCCGCA TCGTCAAATG GCTGATTGCC CTGCCCGTCG GCATCTTTAT



 


51
CTTTTTCAAT GCCTATGTGT ACGGCAACAT CATCACCTAC CGCGCCGTCG


 


101
CGCCCCATCG GACTGCCTTT ATGTCGATGC GGATGAAGCA GTTTGAACAA


 


151
GAAGGTCGCG ATGTCGCACT GGATTACCGC TGGGTGCCCT ACAACCGCAT


 


201
TTCCACCAAC CTGAAAAAAG CCCTGATTGC TTCCGAAGAT GTCCGTTTTG


 


251
CCggacacgg gggcttcGat GGGGACGGCa tTCAAAACGC CATCAGGCGC


 


301
AACCGGAACA GCGGCGAAGT GAAGGCGGGC GGATCGACCA TCAGCCAGCA


 


351
GCTTGCCAAA AACCTCTTCC TCAACGAAAG CCGCAACTAT CTGCGCAAAG


 


401
GGGAAGAGGC GGCCATTACG GCAATGATGG AAGCTGTTAC CGACAAAAAC


 


451
AGGATTTTCG AACTGTATTT AAACTCAATC GAATGGCACT ACGGCgtTTT


 


501
CGGCGCGGAA GCTGCGTCCC GGtatTttTA TAAAAAACCG GCcgcaGACC


 


551
TGACcAAACA GCAggcggcG aaactgacgg tactcgtccc cgccccgttt


 


601
tactactctg accatccaaa aagcaaacgg ctgcgcaaca aaaccaatat


 


651
cgtgctcaga cgcatgggtt cggcaaatta ccccaaagcg aaacggactg


 


701
attgttccag atatggaaat gccgcctgaa ctggggttcg aacggcatat


 


751
gttttctggg acttataa






This corresponds to the amino acid sequence <SEQ ID 2682; ORF 792.ng>:










g792.pep




1
MFRIVKWLIA LPVGIFIFFN AYVYGNIITY RAVAPHRTAF MSMRMKQFEQ



 


51
EGRDVALDYR WVPYNRISTN LKKALIASED VRFAGHGGFD GDGIQNAIRR


 


101
NRNSGEVKAG GSTISQQLAK NLFLNESRNY LRKGEEAAIT AMMEAVTDKN


 


151
RIFELYLNSI EWHYGVFGAE AASRYFYKKP AADLTKQQAA KLTVLVPAPF


 


201
YYSDHPKSKR LRNKTNIVLR RMGSANYPKA KRTDCSRYGN AA*TGVRTAY


 


251
VFWDL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2683>:










m792.seq




1
ATGTTCCGCA TCATCAAATG GCTGATTGCC CTGCCCGTCG GCATCTTTAT



 


51
CTTTTTCAAT GCCTATGTGT ACGGCAACAT CATTACCTAC CGCGCCGTCG


 


101
CGCCCCATCG GACTGCCTTT ATGTCGATGC GGATGAAGCA GTTTGAACAG


 


151
GAAGGTCGCG ATGTCGCACT GGATTACCGC TGGATGCCCT ACAAACGCAT


 


201
TTCCACCAAC CTGAAAAAAG CCCTGATTGC TTCCGAAGAT GCCCGTTTCG


 


251
CCGGGCACGG CGGCTTCGAT TGGGGCGGCA TTCAAAACGC CATCAGGCGC


 


301
AACCGGAACA GCGGCAAAGT GAAGGCGGGC GGCTCGACCA TCAGCCAGCA


 


351
GCTTGCCAAA AACCTGTTTT TAAACGAAAG CCGCAGCTAT ATCCGCAAAG


 


401
GCGAAGAAGC GGCGATTACC GCGATGATGG AAGCCGTTAC CGACAAAGAC


 


451
AGGATTTTTG AACTGTATTT AAACTCAATC GAATGGCACT ACGGCGTTTT


 


501
CGGCGCGGAA GCCGCGTCCC GGTATTTTTA TCAAATACCC GCCGCCAAGC


 


551
TGACCAAACA GCAGGCGGCA AAACTGACGG CGCGCGTCCC CGCCCCGCTC


 


601
TACTACGCCG ACCATCCGAA AAGCAAACGG CTCCGCAACA AAACCAATAT


 


651
CGTGCTCAAA CGCATGGGTT CGGCAGAGTT GCCTGAAAGC GACACGGACT


 


701
GA






This corresponds to the amino acid sequence <SEQ ID 2684; ORF 792>:










m792.pep




1
MFRIIKWLIA LPVGIFIFFN AYVYGNIITY RAVAPHRTAF MSMRMKQFEQ



 


51
EGRDVALDYR WMPYKRISTN LKKALIASED ARFAGHGGFD WGGIQNAIRR


 


101
NRNSGKVKAG GSTISQQLAK NLFLNESRSY IRKGEEAAIT AMMEAVTDKD


 


151
RIFELYLNSI EWHYGVFGAE AASRYFYQIP AAKLTKQQAA KLTARVPAPL


 


201
YYADHPKSKR LRNKTNIVLK RMGSAELPES DTD*






g792/m792 90.4% identity in 230 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2685>:










a792.seq




1
ATGTTCCGCA TCATCAAATG GCTGATTGCC CTGCCCGTCG GCATCTTTAT



 


51
CTTTTTCAAT GCCTATGTGT ACGGCAACAT CATTACCTAC CGCGCCGTCG


 


101
CGCCCCATCG GACTGCCTTT ATGTCGATGC GGATGAAGCA GTTTGAACAG


 


151
GAAGGTCGCG ATGTCGCACT GGATTACCGC TGGATGCCCT ACAAACGCAT


 


201
TTCCACCAAC CTGAAAAAAG CCCTGATTGC TTCCGAAGAT GCCCGTTTCG


 


251
CCGGGCACGG CGGCTTCGAT TGGGGCGGCA TTCAAAACGC CATCAGGCGC


 


301
AACCGGAACA GCGGCAAAGT GAAGGCGGGC GGCTCGACCA TCAGCCAGCA


 


351
GCTTGCCAAA AACCTGTTTT TAAACGAAAG CCGCAGCTAT ATCCGCAAAG


 


401
GCGAAGAAGC GGCGATTACC GCGATGATGG AAGCCGTTAC CGACAAAGAC


 


451
AGGATTTTTG AACTGTATTT AAACTCAATC GAATGGCACT ACGGCGTTTT


 


501
CGGCGCGGAA GCCGCGTCCC GGTATTTTTA TCAAATACCC GCCGCCAAGC


 


551
TGACCAAACA GCAGGCGGCA AAACTGACGG CGCGCGTCCC CGCCCCGCTC


 


601
TACTACGCCG ACCATCCGAA AAGCAAACGG CTCCGCAACA AAACCAATAT


 


651
CGTGCTCAGA CGCATGGGTT CGGCAGAGTT GCCTGAAAGC GACACGGACT


 


701
GA






This corresponds to the amino acid sequence <SEQ ID 2686; ORF 792.a>:










a792.pep




1
MFRIIKWLIA LPVGIFIFFN AYVYGNIITY RAVAPHRTAF MSMRMKQFEQ



 


51
EGRDVALDYR WMPYKRISTN LKKALIASED ARFAGHGGFD WGGIQNAIRR


 


101
NRNSGKVKAG GSTISQQLAK NLFLNESRSY IRKGEEAAIT AMMEAVTDKD


 


151
RIFELYLNSI EWHYGVFGAE AASRYFYQIP AAKLTKQQAA KLTARVPAPL


 


201
YYADHPKSKR LRNKTNIVLR RMGSAELPES DTD*






m792/a792 99.6% identity in 233 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2687>:










g793.seq




1
ATGTTGATTA AAAGCGAATA TAAGCCCCGG ATGCTGCCCA AAGAAGAGCA



 


51
GGTCAAAAAG CCGATGACCA GTAACGGACG GATTAGCTTC GTCCTGATGG


 


101
CAATGGCGGT CTTGTTTGCC TGTCTGATTG CCCGCGGGCT GTATCTGCAG


 


151
ACGGTAACGT ATAACTTTTT GAAAGAACAG GGCGACAACC GGATTGTGCG


 


201
GACTCAAGCA TTGCCGGCTA CACGCGGTAC GGTTTCGGAC CGGAACGGTG


 


251
CGGTTTTGGC GTTGAGCGCG CCGACGGAGT CCCTGTTTGC CGTGCCTAAA


 


301
GATATGAAGG AAATGCCGTC TGCCGCCCAA TTGGAACGCC TGTCCGAGCT


 


351
TGTCGATGTG CCGGTCGATG TTTTGAGGAA CAAACTCGAA CAGAAAGGCA


 


401
AGTCGTTTAT TTGGATCAAG CGGCAGCTCG ATCCCAAGGT TGCCGAAGAG


 


451
GTCAAAGCCT TGGGTTTGGA AAACTTTGTA TTTGAAAAAG AATTAAAACG


 


501
CCATTACCCG ATGGGCAACC TGTTTGCACA CGTCATCGGA TTTACCGATA


 


551
TTGACGGCAA AGGTCAGGAA GGTTTGGAAC TTTCGCTTGA AGACAGCCTG


 


601
TATGGCGAAG ACGGCGCGGA AGTTGTTTTG CGGGACCGGC AGGGCAATAT


 


651
TGTGGACAGC TTGGACTCCC CGCGCAATAA AGCACCGCAA AACGGCAAAG


 


701
ACATCATCCT TTCCCTCGAT CAGAGGATTC AGACCTTGGC CTATGAAGAG


 


751
TTGAACAAGG CGGTCGAATA CCATCAGGCA AAAGCCGGAA CGGTGGTGGT


 


801
TTTGGATGCC CGCACGGGGG AAATCCTCGC CTTGGCCAAT ACGCCCGCCT


 


851
ACGATCCCAA CAGACCCGGC CGGGCAGACA GCGAACAGCG GCGCAACCGT


 


901
GCCGTAACCG ATATGATCGA ACCTGGTTCG GCAATCAAAC CGTTCGTGAT


 


951
TGCGAAGGCA TTGGATGCGG GCAAAACCGA TTTGAACGAA CGGCTGAATA


 


1001
CGCAGCCTTA TAAAATCGGA CCGTCTCCCG TGCGCGATGA TACCCATGTT


 


1051
TACCCCTCTT TGGATGTGCG CGGCATTATG CAGAAATCGT CCAACGTCGG


 


1101
CACAAGCAAA CTGTCTGCGC GTTTCGGCGC CGAAGAAATG TATGACTTCT


 


1151
ATCATGAATT GGGCATCGGT GTGCGTATGC ACTCGGGCTT TCCGGGGGAA


 


1201
ACTGCAGGTT TGTTGAGAAA TTGGCGCAGG TGGCGGCCCA TCGAACAGGC


 


1251
GACGATGTCT TTCGGTTACG GTCTGCAATT GAGCCTGCTG CAATTGGCGC


 


1301
GCGCCTATAC CGCACTGACG CACGACGGCG TTTTGCTGCC GCTCAGCTTT


 


1351
GAGAAGCAGG CGGTTGCGCC GCAAGGCAAA CGCATATTCA AAGAATCGAC


 


1401
CGCGCGCGAG GTACGCAATC TGATGGTTTC CGTAACCGAG CCGGGCGGCA


 


1451
CCGGTACGGC GGGTGCGGTG GACGGTTTCG ATGTCGGCGC TAAAACCGGC


 


1501
ACGGCGCGCA AGTTCGTCAA CGGGCGTTAT GCCGACAACA AACACGTCGC


 


1551
TACCTTTATC GGTTTTGCCC CCGCCAAAAA CCCCCGTGTG ATTGTGGCGG


 


1601
TAACCATCGA CGAACCGACT GCCCACGGCT ATTACGGCGG CGTAGTGGCA


 


1651
GGGCCGCCCT TCAAAAAAAT TATGGGCGGC AGCCTGAACA TCTTGGGCAT


 


1701
TTCCCCGACC AAGCCACTGA CCGCCGCAGC CGTCAAAACA CCGTCTTAA






This corresponds to the amino acid sequence <SEQ ID 2688; ORF 793.ng>:










g793.pep




1
MLIKSEYKPR MLPKEEQVKK PMTSNGRISF VLMAMAVLFA CLIARGLYLQ



 


51
TVTYNFLKEQ GDNRIVRTQA LPATRGTVSD RNGAVLALSA PTESLFAVPK


 


101
DMKEMPSAAQ LERLSELVDV PVDVLRNKLE QKGKSFIWIK RQLDPKVAEE


 


151
VKALGLENFV FEKELKRHYP MGNLFAHVIG FTDIDGKGQE GLELSLEDSL


 


201
YGEDGAEVVL RDRQGNIVDS LDSPRNKAPQ NGKDIILSLD QRIQTLAYEE


 


251
LNKAVEYHQA KAGTVVVLDA RTGEILALAN TPAYDPNRPG RADSEQRRNR


 


301
AVTDMIEPGS AIKPFVIAKA LDAGKTDLNE RLNTQPYKIG PSPVRDDTHV


 


351
YPSLDVRGIM QKSSNVGTSK LSARFGAEEM YDFYHELGIG VRMHSGFPGE


 


401
TAGLLRNWRR WRPIEQATMS FGYGLQLSLL QLARAYTALT HDGVLLPLSF


 


451
EKQAVAPQGK RIFKESTARE VRNLMVSVTE PGGTGTAGAV DGFDVGAKTG


 


501
TARKFVNGRY ADNKHVATFI GFAPAKNPRV IVAVTIDEPT AHGYYGGVVA


 


551
GPPFKKIMGG SLNILGISPT KPLTAAAVKT PS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2689>:










m793.seq




1
ATGTTGATTA AGAGCGAATA TAAGCCTCGG ATGCTGCCCA AAGAAGAGCA



 


51
GGTCAAAAAG CCGATGACCA GTAACGGACG GATCAGCTTC GTCCTGATGG


 


101
CAATAGCGGT CTTGTTTGCC GGTCTGATTG CTCGCGGACT GTATCTGCAG


 


151
ACGGTAACGT ATAACTTTTT GAAAGAACAG GGCGACAACC GGATTGTGCG


 


201
GACTCAAACA TTGCCGGCTA CACGCGGTAC GGTTTCGGAC CGGAACGGTG


 


251
CGGTTTTGGC GTTGAGTGCG CCGACGGAGT CCCTGTTTGC CGTGCCTAAA


 


301
GAGATGAAGG AAATGCCGTC TGCCGCACAA TTGGAACGCC TGTCCGAGCT


 


351
TGTCGATGTG CCGGTTGATG TTTTGAGGAA CAAGCTCGAA CAGAAAGGCA


 


401
AGTCGTTTAT CTGGATTAAG CGGCAGCTCG ATCCCAAGGT TGCCGAAGAG


 


451
GTCAAAGCCT TGGGTTTGGA AAACTTTGTA TTTGAAAAAG AATTAAAACG


 


501
CCATTACCCG ATGGGCAACC TGTTTGCACA CGTCATCGGA TTTACCGATA


 


551
TTGACGGCAA AGGTCAGGAA GGTTTGGAAC TTTCGCTTGA AGACAGCCTG


 


601
CATGGCGAAG ACGGCGCGGA AGTCGTTTTG CGGGACCGGC AGGGCAATAT


 


651
TGTGGACAGC TTGGACTCCC CGCGCAATAA AGCCCCGAAA AACGGCAAAG


 


701
ACATCATCCT TTCCCTCGAT CAGAGGATTC AGACCTTGGC CTATGAAGAG


 


751
TTGAACAAGG CGGTCGAATA CCATCAGGCA AAAGCCGGAA CGGTGGTGGT


 


801
TTTGGATGCC CGCACGGGGG AAATCCTCGC CTTGGCCAAT ACGCCCGCCT


 


851
ACGATCCCAA CAGGCCCGGC CGGGCAGACA GCGAACAGCG GCGCAACCGT


 


901
GCCGTAACCG ATATGATCGA ACCCGGTTCG GCAATCAAAC CGTTTGTGAT


 


951
TGCGAAGGCA TTGGATGCGG GCAAAACCGA TTTGAACGAA CGGCTGAATA


 


1001
CGCAGCCTTA TAAAATCGGA CCGTCTCCCG TGCGCGATAC CCATGTTTAC


 


1051
CCCTCTTTGG ATGTGCGCGG CATCATGCAG AAATCGTCCA ACGTCGGCAC


 


1101
AAGCAAACTG TCTGCGCGTT TCGGTGCCGA AGAAATGTAT GACTTCTATC


 


1151
ATGAGTTGGG CATCGGTGTG CGTATGCACT CGGGCTTTCC GGGCGAAACT


 


1201
GCAGGTTTGT TGAGAAATTG GCGCAGGTGG CGGCCTATCG AACAGGCGAC


 


1251
GATGTCTTTC GGTTACGGCC TGCAATTGAG CCTGCTGCAA TTGGCGCGCG


 


1301
CCTATACCGC ACTGACGCAC GACGGCGTTT TACTGCCGGT CAGCTTTGAA


 


1351
AAACAGGCGG TTGCGCCGCA AGGCAAACGC ATATTCAAAG AATCGACCGC


 


1401
GCGCGAGGTA CGCAATCTGA TGGTTTCCGT AACCGAGCCG GGCGGCACCG


 


1451
GTACGGCGGG TGCGGTGGAC GGTTTCGATG TCGGCGCGAA AACCGGCACG


 


1501
GCGCGCAAGT TCGTCAACGG GCGTTATGCC GACAACAAAC ACATCGCTAC


 


1551
CTTTATCGGT TTTGCCCCCG CCAAAAATCC CCGTGTGATT GTGGCGGTAA


 


1601
CCATTGACGA ACCGACTGCC CACGGTTATT ACGGCGGCGT AGTGGCAGGG


 


1651
CCGCCCTTCA AAAAAATTAT GGGCGGCAGC CTGAACATCT TGGGCATTTC


 


1701
CCCGACCAAG CCACTGACCG CCGCAGCCGT CAAAACACCG TCTTAA






This corresponds to the amino acid sequence <SEQ ID 2690; ORF 793>:










m793.pep




1
MLIKSEYKPR MLPKEEQVKK PMTSNGRISF VLMAIAVLFA GLIARGLYLQ



 


51
TVTYNFLKEQ GDNRIVRTQT LPATRGTVSD RNGAVLALSA PTESLFAVPK


 


101
EMKEMPSAAQ LERLSELVDV PVDVLRNKLE QKGKSFIWIK RQLDPKVAEE


 


151
VKALGLENFV FEKELKRHYP MGNLFAHVIG FTDIDGKGQE GLELSLEDSL


 


201
HGEDGAEVVL RDRQGNIVDS LDSPRNKAPK NGKDIILSLD QRIQTLAYEE


 


251
LNKAVEYHQA KAGTVVVLDA RTGEILALAN TPAYDPNRPG RADSEQRRNR


 


301
AVTDMIEPGS AIKPFVIAKA LDAGKTDLNE RLNTQPYKIG PSPVRDTHVY


 


351
PSLDVRGIMQ KSSNVGTSKL SARFGAEEMY DFYHELGIGV RMHSGFPGET


 


401
AGLLRNWRRW RPIEQATMSF GYGLQLSLLQ LARAYTALTH DGVLLPVSFE


 


451
KQAVAPQGKR IFKESTAREV RNLMVSVTEP GGTGTAGAVD GFDVGAKTGT


 


501
ARKFVNGRYA DNKHIATFIG FAPAKNPRVI VAVTIDEPTA HGYYGGVVAG


 


551
PPFKKIMGGS LNILGISPTK PLTAAAVKTP S*






g793/m793 98.5% identity in 582 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2691>:










a793.seq




1
ATGTTGATTA AGAGCGAATA TAAGCCTCGG ATGCTGCCCA AAGAAGAGCA



 


51
GGTCAAAAAG CCGATGACCA GTAACGGACG GATCAGCTTC GTCCTGATGG


 


101
CAATAGCGGT CTTGTTTGCC GGTCTGATTG CTCGCGGACT GTATCTGCAG


 


151
ACGGTAACGT ATAACTTTTT GAAAGAACAG GGCGACAACC GGATTGTGCG


 


201
GACTCAAACA TTGCCGGCTA CACGCGGTAC GGTTTCGGAC CGGAACGGTG


 


251
CGGTTTTGGC GTTGAGTGCG CCGACGGAGT CCCTGTTTGC CGTGCCTAAA


 


301
GAGATGAAGG AAATGCCGTC TGCCGCACAA TTGGAACGCC TGTCCGAGCT


 


351
TGTCGATGTG CCGGTTGATG TTTTGAGGAA CAAGCTCGAA CAGAAAGGCA


 


401
AGTCGTTTAT CTGGATTAAG CGGCAGCTCG ATCCCAAGGT TGCCGAAGAG


 


451
GTCAAAGCCT TGGGTTTGGA AAACTTTGTA TTTGAAAAAG AATTAAAACG


 


501
CCATTACCCG ATGGGCAACC TGTTTGCACA CGTCATCGGA TTTACCGATA


 


551
TTGACGGCAA AGGTCAGGAA GGTTTGGAAC TTTCGCTTGA AGACAGCCTG


 


601
CATGGCGAAG ACGGCGCGGA AGTCGTTTTG CGGGACCGGC AGGGCAATAT


 


651
TGTGGACAGC TTGGACTCCC CGCGCAATAA AGCCCCGAAA AACGGCAAAG


 


701
ACATCATCCT TTCCCTCGAT CAGAGGATTC AGACCTTGGC CTATGAAGAG


 


751
TTGAACAAGG CGGTCGAATA CCATCAGGCA AAAGCCGGAA CGGTGGTGGT


 


801
TTTGGATGCC CGCACGGGGG AAATCCTCGC CTTGGCCAAT ACGCCCGCCT


 


851
ACGATCCCAA CAGGCCCGGC CGGGCAGACA GCGAACAGCG GCGCAACCGT


 


901
GCCGTAACCG ATATGATCGA ACCCGGTTCG GCAATCAAAC CGTTTGTGAT


 


951
TGCGAAGGCA TTGGATGCGG GCAAAACCGA TTTGAACGAA CGGCTGAATA


 


1001
CGCAGCCTTA TAAAATCGGA CCGTCTCCCG TGCGCGATAC CCATGTTTAC


 


1051
CCCTCTTTGG ATGTGCGCGG CATCATGCAG AAATCGTCCA ACGTCGGCAC


 


1101
AAGCAAACTG TCTGCGCGTT TCGGTGCCGA AGAAATGTAT GACTTCTATC


 


1151
ATGAGTTGGG CATCGGTGTG CGTATGCACT CGGGCTTTCC GGGCGAAACT


 


1201
GCAGGTTTGT TGAGAAATTG GCGCAGGTGG CGGCCTATCG AACAGGCGAC


 


1251
GATGTCTTTC GGTTACGGCC TGCAATTGAG CCTGCTGCAA TTGGCGCGCG


 


1301
CCTATACCGC ACTGACGCAC GACGGCGTTT TACTGCCGGT CAGCTTTGAA


 


1351
AAACAGGCGG TTGCGCCGCA AGGCAAACGC ATATTCAAAG AATCGACCGC


 


1401
GCGCGAGGTA CGCAATCTGA TGGTTTCCGT AACCGAGCCG GGCGGCACCG


 


1451
GTACGGCGGG TGCGGTGGAC GGTTTCGATG TCGGCGCGAA AACCGGCACG


 


1501
GCGCGCAAGT TCGTCAACGG GCGTTATGCC GACAACAAAC ACATCGCTAC


 


1551
CTTTATCGGT TTTGCCCCCG CCAAAAATCC CCGTGTGATT GTGGCGGTAA


 


1601
CCATTGACGA ACCGACTGCC CACGGTTATT ACGGCGGCGT AGTGGCAGGG


 


1651
CCGCCCTTCA AAAAAATTAT GGGCGGCAGC CTGAACATCT TGGGCATTTC


 


1701
CCCGACCAAG CCACTGACCG CCGCAGCCGT CAAAACACCG TCTTAA






This corresponds to the amino acid sequence <SEQ ID 2692; ORF 793.a>:










a793.pep




1
MLIKSEYKPR MLPKEEQVKK PMTSNGRISF VLMAIAVLFA GLIARGLYLQ


 


51
TVTYNFLKEQ GDNRIVRTQT LPATRGTVSD RNGAVLALSA PTESLFAVPK


 


101
EMKEMPSAAQ LERLSELVDV PVDVLRNKLE QKGKSFIWIK RQLDPKVAEE


 


151
VKALGLENFV FEKELKRHYP MGNLFAHVIG FTDIDGKGQE GLELSLEDSL


 


201
HGEDGAEVVL RDRQGNIVDS LDSPRNKAPK NGKDIILSLD QRIQTLAYEE


 


251
LNKAVEYHQA KAGTVVVLDA RTGEILALAN TPAYDPNRPG RADSEQRRNR


 


301
AVTDMIEPGS AIKPFVIAKA LDAGKTDLNE RLNTQPYKIG PSPVRDTHVY


 


351
PSLDVRGIMQ KSSNVGTSKL SARFGAEEMY DFYHELGIGV RMHSGFPGET


 


401
AGLLRNWRRW RPIEQATMSF GYGLQLSLLQ LARAYTALTH DGVLLPVSFE


 


451
KQAVAPQGKR IFKESTAREV RNLMVSVTEP GGTGTAGAVD GFDVGAKTGT


 


501
ARKFVNGRYA DNKHIATFIG FAPAKNPRVI VAVTIDEPTA HGYYGGVVAG


 


551
PPFKKIMGGS LNILGISPTK PLTAAAVKTP S*






a793/m793 100.0% identity in 581 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2693>:










g794.seq




1
gtgcgtttca ATCATTTCAT AATGGTAACG ATTATTATAT ATGTGATTTC


 


51
CCCTGCAAAC AAGCCGGTCC GCCGCCCCGG CGTTCCCACT TATCCGGCTT


 


101
TGCCTTATAA TTGCTTTTTT TATGTAACAG ATTCACCTAT GAATTTCCCC


 


151
AAAACAGCGG CCTCCCTGCT GCTGCTTCTC GCCTCCCTCG CCGCACACGC


 


201
GCTCGATACC GGCCGCATTC CGCAAAACGA AATCGCTGTA TATGTCCAAG


 


251
AGCTTGACAG CGGAAAAGTC ATCATTGACC ACCGTGCCGG CATACCCGTC


 


301
AATCCCGCGT CCACGATGAA GCTCGTTACC GCGTTTGCCG CCTTCAAAAC


 


351
CTTCGGCAGC AATTACCGCT GGGCGACCGA GTTTAAAAGC AACGGTACGG


 


401
TAAACGACGG CACGCTTGAC GGAAACCTGT ATTGGGCGGG CAGCGGCGAC


 


451
CCCGTTTTCA ATCAGGAAAA CCTGCTTGCC GTCCAACGCC AGTTGCGCGA


 


501
CAAAGGCATC CGCAATATCA CGGGGCGCCT GATGCTCGAC CACAGCCTGT


 


551
GGGGCGAAGT CGGCAGTCCC GACCATTTTG AAGCCGACAG CGGTTCGCCG


 


601
TTTATGACGC CCCCAAATCC GACTATGCTG TCTGCCGGTA TGGTTATGGT


 


651
GCGCGCCGAA CGCAATGCCG CCGGCAGTAC CGACATCCTC ACCGATCCGC


 


701
CTTTGCCGCA TATTTTTGCC CAAAACAACT TGAAAATTAC CGCCTCCCAA


 


751
GCTGCCTGCC CTTCGGTCAA AAAACTGATG CGCGCATCTT TTTCGGGCAA


 


801
TACGCTGAAA TTGCGCGGCA ATATTCCCGA AAGCTGTTTG GGCAAGCCTG


 


851
TCGGTGTCCG GATGTTCGCG CTTGACGAAC TGATCCGCCA AAGTTTTACC


 


901
AACCGCTGGC TGCTCGGCGG CGGACGGATT TCAGACGGCA TCGGCATAGC


 


951
CGACACACCG GAAGGCGCGC AGACGCTTGC CGTTGCACAC TCCAAACCGA


 


1001
TGAAGGAAAT TTTGACGGAC ATGAACAAGC GTTCGGACAA TCTGATTGCG


 


1051
CGTTCCGTCT TCCTCAAACT CGGCGGCGAC GGCAAACTGC CCGCCGTTTC


 


1101
CGAACAGGCG GCGTCTGCCG TCCGGCGAGA ACTTGCCGTA TCGGGCATCG


 


1151
ATGTTGCGGA TTTGGTTTTG GAAAACGGTT CGGGTCTGTC CAGAAAAGAA


 


1201
AGGGTAACGG CGAGAATGAT GGCGCAAATG TTGGAAACGG CTTATTTCAG


 


1251
CCCGTTTGCA CAAGATTTCA TCGACACGCT GCCCATCGCC GGCACAGACG


 


1301
GGACTTTACG CAACCGCTTC AAACAAAGCG GCGGGCTGTT GCGCTTAAAA


 


1351
ACCGGCACGC TCAACAATGT CCGCGCCCTT GCAGGTTATT GGCTGGGCGA


 


1401
CAAACCGATG GCGGTGGTCG TCATCATCAA CAGCGGCCGC GCCGTTTCCC


 


1451
TGCTGCCCGA CTTGGACAAC TTCGTTGCCA AAAACATCAT CTCCGGCGGC


 


1501
GACGGCTGGC TGGATGCGAA ACTGATGTGC AAAGAACGCC GCGCCTGA






This corresponds to the amino acid sequence <SEQ ID 2694; ORF 794.ng>:










g794.pep




1
VRFNHFIMVT IIIYVISPAN KPVRRPGVPT YPALPYNCFF YVTDSPMNFP


 


51
KTAASLLLLL ASLAAHALDT GRIPQNEIAV YVQELDSGKV IIDHRAGIPV


 


101
NPASTMKLVT AFAAFKTFGS NYRWATEFKS NGTVNDGTLD GNLYWAGSGD


 


151
PVFNQENLLA VQRQLRDKGI RNITGRLMLD HSLWGEVGSP DHFEADSGSP


 


201
FMTPPNPTML SAGMVMVRAE RNAAGSTDIL TDPPLPHIFA QNNLKITASQ


 


251
AACPSVKKLM RASFSGNTLK LRGNIPESCL GKPVGVRMFA LDELIRQSFT


 


301
NRWLLGGGRI SDGIGIADTP EGAQTLAVAH SKPMKEILTD MNKRSDNLIA


 


351
RSVFLKLGGD GKLPAVSEQA ASAVRRELAV SGIDVADLVL ENGSGLSRKE


 


401
RVTARMMAQM LETAYFSPFA QDFIDTLPIA GTDGTLRNRF KQSGGLLRLK


 


451
TGTLNNVRAL AGYWLGDKPM AVVVIINSGR AVSLLPDLDN FVAKNIISGG


 


501
DGWLDAKLMC KERRA*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2695>:










m794.seq




1
GTGCGTCTCA ATCATTTCAT AATGATAGCG ATTATTATAT ATGTGATTTC


 


51
CCCTGCAAAC AAGCCGGCCC GCCGCCACAG CGTTCCCACT TATCCGGCTT


 


101
TGCCTTATAA TTGCTTTTTT TATGTAACAG ATTTACCTAT GAATTTCCCC


 


151
AAAACAGCGG CCTCCCTGCT GCTGCTTCTC GCCTCCCTCG CCGCACACGC


 


201
GCTCGATACC GGCCGCATTC CGCAAAACGA AATCGCCGTA TATGTCCAAG


 


251
AGCTTGACAG CGGAAAAGTC ATCATTGACC ACCGCTCGGA TGTCCCCGTC


 


301
AACCCCGCCT CCACAATGAA ACTCGTTACC GCGTTTGCCG CCTTCAAAAC


 


351
CTTCGGCAGC AATTACCGCT GGGCGACCGA GTTTAAAAGC AACGGTACGG


 


401
TAAACGACGG CACGCTTGAC GGAAACCTAT ATTGGGCGGG CAGCGGCGAC


 


451
CCCGTTTTCA ATCAGGAAAA CCTGCTTGAT GCTCAAAAAC AGTTGCGCGA


 


501
ACAAGGCATA CTCAATATCA CGGGACACCT GATGCTCGAC CACAGCCTGT


 


551
GGGGCGAAGT CGGCAGCCCC GACGATTTCG AAGCCGACAG CGGTTCGCCG


 


601
TTTATGACGC CCCCCAATCC AACTATGCTG TCTGCCGGTA TGGTTATGGT


 


651
GCGCGCCGAA CGCAATGCCG CCGGCAGTAC CGACATCCTC ACCGATCCGC


 


701
CTTTGCCGCA TATTTTCGCC CAAAACAACT TGAAAATTAC CGCCTCCCAA


 


751
GCTGCCTGCC CTTCGATCAA AAAACTGATG CGTGCATCTT TTTCGGACAA


 


801
TACGCTGAAA TTGCGCGGCA ATATTCCCGA GAGCTGTTTG GGCAAGCCTG


 


851
TCGGTGTCCG GATGTTCGCG CTTGACGAAC TGATCCGGCA AAGTTTTACC


 


901
AACCACTGGC TGCTCGGCGG CGGACGGATT TCAGACGGTA TCGGCATAGC


 


951
CGACACGCCG GAAGGCGCGC AGACACTTGC CGTTGCACAC GCCAAACCGA


 


1001
TGAAAGAAAT TTTGACGGAC ATGAACAAGC GTTCGGACAA TCTAATTGCG


 


1051
CGTTCCGTCT TCCTCAAACT CGGCGGCGAC GGCAAACTGC CCGCCGTTTC


 


1101
CGAACAGGCG GCGTCTGCCG TCCGGCGCGA ACTTGCCGTA TCGGGCATCG


 


1151
ATGTTGCGGA TTTGGTTTTG GAAAACGGTT CGGGCCTGTC CAGAAAAGAA


 


1201
AGGGTAACGG CGAGAATGAT GGCGCAAATG TTGGAAACGG CTTATTTCAG


 


1251
CCCGTTTGCA CAAGATTTCA TCGACACGCT ACCCATCGCC GGCACAGACG


 


1301
GAACTTTACG CAACCGCTTC AAACAAAGCG GCGGGCTGTT GCGCTTAAAA


 


1351
ACCGGCACGC TCAACAATGT CCGCGCCCTT GCAGGTTATT GGCTGGGCGA


 


1401
CAAACCGATG GCGGTGGTCG TCATCATCAA CAGCGGCCGC GCCGTTTCCC


 


1451
TGCTGCCAGA CTTGGACAAC TTCGTTGCCA ACAACATCAT CTCCGGCGGC


 


1501
GATGGCTGGC TGGATGCGAA ACTGATGTGC AAAGAACGCC GAGCCTGA






This corresponds to the amino acid sequence <SEQ ID 2696; ORF 794>:










m794.pep




1
VRLNHFIMIA IIIYVISPAN KPARRHSVPT YPALPYNCFF YVTDLPMNFP


 


51
KTAASLLLLL ASLAAHALDT GRIPQNEIAV YVQELDSGKV IIDHRSDVPV


 


101
NPASTMKLVT AFAAFKTFGS NYRWATEFKS NGTVNDGTLD GNLYWAGSGD


 


151
PVFNQENLLD AQKQLREQGI LNITGHLMLD HSLWGEVGSP DDFEADSGSP


 


201
FMTPPNPTML SAGMVMVRAE RNAAGSTDIL TDPPLPHIFA QNNLKITASQ


 


251
AACPSIKKLM RASFSDNTLK LRGNIPESCL GKPVGVRMFA LDELIRQSFT


 


301
NHWLLGGGRI SDGIGIADTP EGAQTLAVAH AKPMKEILTD MNKRSDNLIA


 


351
RSVFLKLGGD GKLPAVSEQA ASAVRRELAV SGIDVADLVL ENGSGLSRKE


 


401
RVTARMMAQM LETAYFSPFA QDFIDTLPIA GTDGTLRNRF KQSGGLLRLK


 


451
TGTLNNVRAL AGYWLGDKPM AVVVIINSGR AVSLLPDLDN FVANNIISGG


 


501
DGWLDAKLMC KERRA*






g794/m794 95.5% identity in 515 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2697>:










a794.seq




1
GTGCGTCTCA ATCATTTCAT AATGATAGCG ATTATTATAT ATGTGATTTC


 


51
CCCTGCAAAC AAGCCGGCCC GCCGCCACAG CGTTCCCACT TATCCGGCTT


 


101
TGCCTTATAA TTGCTTTTTT TATGTAACAG ATTTACCTAT GAATTTCCCC


 


151
AAAACAGCGG CCTCCCTGCT GCTGCTTCTC GCCTCCCTCG CCGCACACGC


 


201
GCTCGATACA GGTCGCATTC CGCAAAACGA AATCGCCGTA TATGTCCAAG


 


251
AGCTTGACAG CGGAAAAGTC ATCATTGACC ACCGCTCGGA TGTCCCCGTC


 


301
AACCCCGCCT CCACAATGAA ACTCGTTACC GCGTTTGCCG CCTTCAAAAC


 


351
CTTCGGCAGC AATTACCGCT GGGCGACCGA GTTTAAAAGC AACGGTACGG


 


401
TAAACGACGG CACGCTTGAC GGAAACCTGT ATTGGGCGGG CAGCGGCGAC


 


451
CCCGTTTTCA ATCAGGAAAA CCTGCTTGCC GTCCAACGCC AGTTGCGCGA


 


501
ACAAGGCATA CGCAATATCA CGGGACACCT GATGCTCGAC CACAGCCTGT


 


551
GGGGCGAAGT CGGCAGCCCC GACGATTTCG AAGCCGACAG CGGTTCGCCG


 


601
TTTATGACGC CCCCCAATCC AACTATGCTG TCTGCCGGTA TGGTTATGGT


 


651
GCGCGCCGAA CGCAATGCCG CCGACAGTAC CGACATCCTC ACCGATCCGC


 


701
CTTTGCCGCA TATTTTCGCC CAAAACAACT TGAAAATTAC CGCCTCCCAA


 


751
GCTGCCTGCC CTTCGATCAA AAAACTGATG CGTGCATCTT TTTCGGACAA


 


801
TACGCTGAAA TTGCGCGGCA ATATTCCCGA GAGCTGTTTG GGCAAGCCTG


 


851
TCGGTGTCCG GATGTTCGCG CTTGACGAAC TGATCCGGCA AAGTTTTACC


 


901
AACCACTGGC TGCTCGGCGG CGGACGGATT TCAGACGGCA TCGGCATATC


 


951
CGACACGCCG GAAGGCGCGC AGACGCTTGC CGTTGCACAC TCAAAGCCGA


 


1001
TGAAGGAAAT TTTGACGGAC ATGAACAAGC GTTCGGACAA TCTAATTGCG


 


1051
CGTTCCGTCT TCCTCAAACT CGGCGGCGAC GGCAAACTGC CCGCCGTTTC


 


1101
CGAACAGGCA GCGTCTGCCG TCCGGCGTGA ACTTGCCGTG TCGGGCATCG


 


1151
ATGTTGCGGA TTTGGTTTTG GAAAACGGTT CAGGTCTGTC CAGAAAAGAA


 


1201
AGGGTAACGG CGAGAATGAT GGCGCAAATG TTGGAAACGG CTTATTTCAG


 


1251
CCCGTTTGCA CAAGATTTCA TCGATACGCT GCCCATCGCC GGCACAGACG


 


1301
GGACTTTACG CAACCGCTTC AAACAAAGCG GCGGGCTGTT GCGCTTAAAA


 


1351
ACCGGCACGC TCAACAATGT CCGCGCCCTT GCAGGTTATT GGCTGGGCGA


 


1401
CAAACCGATG GCGGTGGTCG TCATCATCAA CAGCGGCCGC GCCGTTTCCC


 


1451
TGCTGCCCGA CTTGGACAAC TTCGTTGCCA ACAACATCAT CTCCGGCGGC


 


1501
GATGGCTGGC TGGATGCGAA ACTGATGTGC AAAGAACGCC GAGCCTGA






This corresponds to the amino acid sequence <SEQ ID 2698; ORF 794.a>:










a794.pep




1
VRLNHFIMIA IIIYVISPAN KPARRHSVPT YPALPYNCFF YVTDLPMNFP


 


51
KTAASLLLLL ASLAAHALDT GRIPQNEIAV YVQELDSGKV IIDHRSDVPV


 


101
NPASTMKLVT AFAAFKTFGS NYRWATEFKS NGTVNDGTLD GNLYWAGSGD


 


151
PVFNQENLLA VQRQLREQGI RNITGHLMLD HSLWGEVGSP DDFEADSGSP


 


201
FMTPPNPTML SAGMVMVRAE RNAADSTDIL TDPPLPHIFA QNNLKITASQ


 


251
AACPSIKKLM RASFSDNTLK LRGNIPESCL GKPVGVRMFA LDELIRQSFT


 


301
NHWLLGGGRI SDGIGISDTP EGAQTLAVAH SKPMKEILTD MNKRSDNLIA


 


351
RSVFLKLGGD GKLPAVSEQA ASAVRRELAV SGIDVADLVL ENGSGLSRKE


 


401
RVTARMMAQM LETAYFSPFA QDFIDTLPIA GTDGTLRNRF KQSGGLLRLK


 


451
TGTLNNVRAL AGYWLGDKPM AVVVIINSGR AVSLLPDLDN FVANNIISGG


 


501
DGWLDAKLMC KERRA*






a794/m794 98.6% identity in 515 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2699>:










g900.seq




1
ATGccgTCTG AAATGCCGTC TGAAACGTGG CAGGCGGAGG TTCGGACGGC


 


51
ATTGGGTTTA TTTCAACGGG CGGATGCCGA CCGCATCGCG TACTTTATCC


 


101
AACAATTCGC GCGCTTCTTT GCGCGCTTTT TGCGCGcctg cctGCAAAAT


 


151
CTCTTCGATT TGCGAAGGAT TAGAGGTCAA TGCGTTGTAG CGTTCGCGCA


 


201
GTTCTGCCAA TTCGGCGTTG ATTTTCGCCG CCGAAAGTTT TTTCGCCTCG


 


251
CCCCAAGCCA AGCCGTCGGC AAGCATTTGC GTAAATTCCG CCGTTTCAGA


 


301
CGGCGTGGAG AAGGCTTTAT AGATTTCAAA CAAAGGGCTT TCGTCGGGCT


 


351
GTTTCGGCTC GCCCGGCTCT TTCATGTTGG TAATGATTTT GTTGACCGAT


 


401
TTTTGGGTTT TTTTGTCGTT TTCCCAAAGC GGAATGGTAT TGCCGTAGGA


 


451
TTTGGACATT TTGCGTCCGT CCAAACCGAC CAAGAGTTCG ACGTTTTCGT


 


501
CGATTTTCAC TTCGGGCagg GTGaagagtt cTTGGAaacc gtgggtgaag


 


551
cggccggcAa tgtcgcgcgc cATTTcgacg tgttgGATTT GGTCGCGCCC


 


601
GACGGGGACT TCGTTGGCGT TGAACATCAA AATGTCGGCA GTCATCAGAA


 


651
TCGGATAACT GAACAAACCC ATTTCCACAC CGAAATCGGG GTCTTCCTGC


 


701
CCGTTTTCCG CATTGGCTTG AACGGCGGCT TTGTAGGCGT GGGCGCGGTT


 


751
CATCAAACCC TTGGCGGTGA TGCAGGTCAG AATCCAGTTC AACTCCATCA


 


801
CTTCGGGAAT GTCGCTTTGG CGGTAGAAGG TGGTGCGCTC GGGGTCGAGT


 


851
CCGCAGGCAA GCCAAGTGGC GGCAACGGCt tgGGTGGATT GGTGAATCAT


 


901
CTCCTGCTCG TGGCATTTGA TGATGCCGTG GTAATCGGCG AGGAAGAGGA


 


951
AGGATTCGGT ATCGGGGTTT TGCGCCGCGC GGACGGCGGG GCGGATGGCG


 


1001
CCGACGTAGT TGCCCAGATG CGGGGTGCCG GTGGTGGTTA CGCCGGTCAG


 


1051
AACTCGTTTT TTGCTCATAA AAATGTCCTT ACGGCAGCAA TGCCGTCTGA


 


1101
AAGGGAAAa. gatgcgCCGA TTATACCCGA TTTGCCACAT ACATCCAGCC


 


1151
GacaACagaC TTTTCCATAT TAA






This corresponds to the amino acid sequence <SEQ ID 2700; ORF 900.ng:










g900.pep




1
MPSEMPSETW QAEVRTALGL FQRADADRIA YFIQQFARFF ARFLRACLQN


 


51
LFDLRRIRGQ CVVAFAQFCQ FGVDFRRRKF FRLAPSQAVG KHLRKFRRFR


 


101
RRGEGFIDFK QRAFVGLFRL ARLFHVGNDF VDRFLGFFVV FPKRNGIAVG


 


151
FGHFASVQTD QEFDVFVDFH FGQGEEFLET VGEAAGNVAR HFDVLDLVAP


 


201
DGDFVGVEHQ NVGSHQNRIT EQTHFHTEIG VFLPVFRIGL NGGFVGVGAV


 


251
HQTLGGDAGQ NPVQLHHFGN VALAVEGGAL GVESAGKPSG GNGLGGLVNH


 


301
LLLVAFDDAV VIGEEEEGFG IGVLRRADGG ADGADVVAQM RGAGGGYAGQ


 


351
NSFFAHKNVL TAAMPSEREK DAPIIPDLPH TSSRQQTFPY *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2701>:










m900.seq




1
ATGCCGTCTG AAACGCGGCA GGCGGAGGTT CGGACGGCAT CGGGTTCATT


 


51
TCAACGGGCG GATGcCGACC GCATCgG.TA CTTTGTCCAA TAATTCGCGT


 


101
GCTTCTTTAC GCGCTTTCGC CGCGCCTGCC TGCAAAATCT CTTCGATTTG


 


151
CGAAGGGTCG GCGGTCAGCT CGTTGTAGCG TTCGCGCGGT TCGGCGAGTT


 


201
CGGCGTTGAT TTTCGCCGCC AAAAGTTTTT TGGCTTCACC CCACGCCAAG


 


251
CCGTCGGCAA GCATTTTCGT AAATTCCACC GTTTCAGACG GCGTGGAGAA


 


301
GGCTTTGTAG ATTTCAAACA ATGGGCTTTC GTCGGGCTGT TTCGGCTCGC


 


351
CCGGCTCTTT CATATTGGTG ATGATTTTGT TGACCGATTT TTGGGTTTTT


 


401
tTGTCGTTTT CCCAAAGCGG AATGGTGTTG CCGTAGGATT TGGACATTTT


 


451
GCGTCCGTCC AAACCGACCA AGAGTTCGAC GTTTTCATCG ATTTTCACTT


 


501
CGGGCAGGGT GAAGAGTTCC CGGAAGCGGT GGTTGAAGCG GCCGGCGATG


 


551
TCGCGCGCCA TTTCGACGTG TTGGATTTGG TCGCGCCCGA CgGGCaCTTC


 


601
GTTGGCGTTG AACATCAGAA TATCGGCAGT CATCAGAATC GGATAACTGA


 


651
ACAAACCCAT TTCCACACCG AAATCAGGGT CTTCCTGCCC GTTTTCTGCA


 


701
TTTGCCTGCA CGGCGGCTTT GTAGGCATGG GCGCGGTTCA TCAAACCCTT


 


751
GGCAGTGATG CAGGTCAGAA TCCAGTTCAA TTCCATCACT TCgGGAGTGT


 


801
CGCTTTGGCG GTAGAAGGTG GTGCGCTCGG GGTCGAGTCC GCAgGCAAGC


 


851
CAAGTGGCGG CAACGGCTTG GGTGGATTGG TGAATCATCT CCGGCTCGTG


 


901
GCATTTGATG ATACCGTGGT AATCGGCGAG GAAGAGGAAG GATTCGGTAT


 


951
CGAGGTTTTG CGCCGCGCGG ACGGCGGGGC GGATGGCGCC GACGTAGTTG


 


1001
CCCAGATGCG GGATGCCGGT GGTGGTTACG CCGGTCAGAA CTCGTTTTTT


 


1051
GCTCATAAAA ATGTCCTTGC GGCATCAATG CCGTCTGAAA GGGAAAAAGA


 


1101
TGTGCCGATT ATACCCGATT TGCCACCTAC ATCCAGCCGA CAACAGACTT


 


1151
TTCCATATTA A






This corresponds to the amino acid sequence <SEQ ID 2702; ORF 900>:










m900.pep




1
MPSETRQAEV RTASGSFQRA DADRIXYFVQ *FACFFTRFR RACLQNLFDL


 


51
RRVGGQLVVA FARFGEFGVD FRRQKFFGFT PRQAVGKHFR KFHRFRRRGE


 


101
GFVDFKQWAF VGLFRLARLF HIGDDFVDRF LGFFVVFPKR NGVAVGFGHF


 


151
ASVQTDQEFD VFIDFHFGQG EEFPEAVVEA AGDVARHFDV LDLVAPDGHF


 


201
VGVEHQNIGS HQNRITEQTH FHTEIRVFLP VFCICLHGGF VGMGAVHQTL


 


251
GSDAGQNPVQ FHHFGSVALA VEGGALGVES AGKPSGGNGL GGLVNHLRLV


 


301
AFDDTVVIGE EEEGFGIEVL RRADGGADGA DVVAQMRDAG GGYAGQNSFF


 


351
AHKNVLAASM PSEREKDVPI IPDLPPTSSR QQTFPY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 900 shows 87.0% identity over a 386 aa overlap with a predicted ORF (ORF 900.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2703>:









a900.seq (partial)










1
GAGGTTCGGA CGGCATTGGG TTTATTTCAA CGGGCGGATA CCGACCGCAT



 


51
CACGTACTTT GCCCAATAAT TCGCGTGCTT CTTTACGCGC TTTTTGCGCG


 


101
CCTGCCTGCA AAATCTCTTC GATTTGCGAA GGGTCGGCGG TCAGCTCGTT


 


151
GTAGCGTTCG CGCGGTTCGG CGAGTTCGGC GTTGATTTTC GCCGCCAAAA


 


201
GTTTTTTTGC CTCGCCCCAA GCCAAGCCGT CGGCAAGCAT TTTCGTAAAT


 


251
TCTGCCGTTT CAGACGGCGT GGAGAAAGCT TTGTAGATTT CAAACAGAGG


 


301
GCTTTCGTCG GGCTTCTTCG GCTCGCCCGG CTCTTTCATA TTGGTGATGA


 


351
TTTTGTTGAC CGATTTTTGG GTTTTTTTGT CGTTTTCCCA AAGCGGAATG


 


401
GTGTTGCCGT AGGATTTGGA CATTTTGCGT CCGTCCAAAC CAACCAAGAG


 


451
TTCGACGTTT TCGTCGATTT TCACTTCGGG CAGTGTGAAG AGTTCCCGGA


 


501
AGCGGTGGTT GAAGCGGCCG GCAATATCGC GTGCCATTTC AACGTGTTGG


 


551
ATTTGGTCGC GACCGACTGG AACTTCATGG GCATTGAACA TGAGAATGTC


 


601
GGCAGTCATG AGGATAGGGT AGCTGTACAA ACCCATTTCC ACGCCGAAAT


 


651
CGGGGTCTTC CTGCCCGTTT TCCGCATTTG CCTGCACGGC GGCTTTGTAG


 


701
GCGTGGGCGC GGTTCATCAA ACCCTTGGCG GTGATGCAGG TCAGAATCCA


 


751
GTTCAATTCC ATCACTTCGG GAATGTCGCT TTGACGGTAG AAGGTGGTGC


 


801
GCTCGGGGTC GAGTCCGCAG GCAAGCCAAG TGGCGGCAAC GGCTTGGGTG


 


851
GATTGGTGAA TCATCTCCGG CTCGTGGCAT TTGATGATAC CGTGGTAATC


 


901
GGCGAGGAAG AGGAAGGATT CGGTATCAGG GTTTTGCGCC GCGCGGACGG


 


951
CGGGGCGGAT AGCACCGACG TAGTTGCCCA GATGCGGGAT GCCGGTGGTG


 


1001
GTTACGCCGG TCAGAACTCG TTTTTTGCTC ATAAAAATGT CCTTGCGGCA


 


1051
TCAATGCCGT CTGAAAGGGA AAAAGATGCG CCGATTATAC CCGATTTGCC


 


1101
ACCTACATCC AGCCGACAAC AGACTTTTCC ATATTAA






This corresponds to the amino acid sequence <SEQ ID 2704; ORF 900.a>:









a900.pep (partial)










1
EVRTALGLFQ RADTDRITYF AQ*FACFFTR FLRACLQNLF DLRRVGGQLV



 


51
VAFARFGEFG VDFRRQKFFC LAPSQAVGKH FRKFCRFRRR GESFVDFKQR


 


101
AFVGLLRLAR LFHIGDDFVD RFLGFFVVFP KRNGVAVGFG HFASVQTNQE


 


151
FDVFVDFHFG QCEEFPEAVV EAAGNIACHF NVLDLVATDW NFMGIEHENV


 


201
GSHEDRVAVQ THFHAEIGVF LPVFRICLHG GFVGVGAVHQ TLGGDAGQNP


 


251
VQFHHFGNVA LTVEGGALGV ESAGKPSGGN GLGGLVNHLR LVAFDDTVVI


 


301
GEEEEGFGIR VLRRADGGAD STDVVAQMRD AGGGYAGQNS FFAHKNVLAA


 


351
SMPSEREKDA PIIPDLPPTS SRQQTFPY*






m900/n900 RR 4% identity in 378 aa overlap





g901.seq not found yet

g901.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2705>:










m901.seq




1
ATGCCCGATT TTTCGATGTC CAATTTGGCC GTTGCCTTTT CCATCACATT


 


51
GGCTGCCGGT TTGTTTACCG TATTAkGyAG TGGCTTGGTG ATGTTTTCCA


 


101
AAACGCCCAA TCCGCGTGTG TTGTCGTTTG GTTTGGCGTT TGCCGGCGGT


 


151
GCGATGGTAT ATGTTTCCCT GACGGAGATT TTCAGTAAGT CCAGCGAGGC


 


201
GTTCGCTGAA ATTTATGATA AAGACCACGC GTTTGCGGCG GCGACCATGG


 


251
CATTTTTGGC CGGGATGGGC GGCATTGCGC TGATTGACCG TCTGGTGCCG


 


301
AACCCGCATG AAACTTTAGA CGCGCAAGAC CCGTCGTTTC AAGAAAGCAA


 


351
ACGCCGCCAT ATCGCGCGAG TCGGCATGAT GGCGGCGTTT GCGATTACTG


 


401
CGCACAATTT CCCCGAAGGC TTGGCGACGT TTTTTGCCAC ATTGGAAAAT


 


451
CCAGCAGTCG GGATGCCTTT GGCCTTGGCG ATTGCCATCC ATAATATTCC


 


501
GGAGGGCATT TCCATCGCCG CGCCGGTTTA TTTTGCCACC CGCAGCCGTA


 


551
AGAAAACGGT GTGGGCGTGT CTGCTATCCG GCTTGGCCGA GCCGTTGGGG


 


601
GCGGCTTTGG GCTATTTGGT TTTGCAGCCG TTTTTGTCGC CTGCCGTGTT


 


651
TGGTTCGGTA TTCGGCGTGA TAGCCGGTGT GATGGTGTTT TTGGCGTTGG


 


701
ACGAGCTGnt GCCGGCTGCC AAACGCTATT CAGACGGCCA TGAAACCGTT


 


751
TACGGCCTGA CAACGGGTAT GGCGGTGATT GCCGTCAGCC TGGTATTGTT


 


801
CCATTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2706; ORF 901>:










m901.pep




1
MPDFSMSNLA VAFSITLAAG LFTVLXSGLV MFSKTPNPRV LSFGLAFAGG


 


51
AMVYVSLTEI FSKSSEAFAE IYDKDHAFAA ATMAFLAGMG GIALIDRLVP


 


101
NPHETLDAQD PSFQESKRRH IARVGMMAAF AITAHNFPEG LATFFATLEN


 


151
PAVGMPLALA IAIHNIPEGI SIAAPVYFAT RSRKKTVWAC LLSGLAEPLG


 


201
AALGYLVLQP FLSPAVFGSV FGVIAGVMVF LALDELXPAA KRYSDGHETV


 


251
YGLTTGMAVI AVSLVLFHF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2707>:










a901.seq




1
ATGCCCGATT TTTCGATGTC CAATTTGGCC GTTGCCTTTT CCATTACGTT


 


51
GGCTGCCGGT TTGTTTACCG TATTAGGCAG CGGCTTGGTG ATGTTTTCCA


 


101
AAACGCCCAA TCCGCGCGTG TTGTCGTTTG GTTTGGCATT TGCCGGCGGT


 


151
GCGATGGTGT ATGTTTCCCT GACGGAGATT TTCAGTAAGT CCAGCGAGGC


 


201
GTTCGCTGAA ATTTATGATA AAGACCACGC GTTTGCGGCG GCGACCATGG


 


251
CATTTTTGGC AGGGATGGGC GGCATTGCGC TGATTGACCG TCTGGTGCCG


 


301
AACCCGCATG AAACTTTAGA CGCGCAAGAC CCGTCGTTTC AAGAAAGCAA


 


351
ACGCCGCCAT ATCGCGCGAG TCGGCATGAT GGCGGCGTTT GCGATTACTG


 


401
CGCACAATTT CCCCGAAGGC TTGGCGACGT TTTTTGCCAC ATTGGAAAAT


 


451
CCAGCAGTCG GGATGCCTTT GGCCTTGGCG ATTGCCATCC ATAATATTCC


 


501
GGAGGGCATT TCCATCGCCG CGCCGGTTTA TTTTGCCACC CGCAGCCGTA


 


551
AGAAAACGGT GTGGGCGTGT CTGCTATCCG GCTTGGCCGA GCCGTTGGGG


 


601
GCGGCTTTGG GCTATTTGGT TTTGCAGCCG TTTTTGTCGC CTGCCGTGTT


 


651
TGGTTCGGTA TTCGGCGTGA TAGCCGGTGT GATGGTGTTT TTGGCGTTGG


 


701
ACGAGCTGCT GCCGGCTGCC AAACGCTATT CAGACGGCCA TGAAACCGTT


 


751
TACGGCCTGA CAATGGGCAT GGCGGTGATT GCCGTCAGCC TGGTATTGTT


 


801
CCATTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2708; ORF 901.a>:










a901.pep




1
MPDFSMSNLA VAFSITLAAG LFTVLGSGLV MFSKTPNPRV LSFGLAFAGG


 


51
AMVYVSLTEI FSKSSEAFAE IYDKDHAFAA ATMAFLAGMG GIALIDRLVP


 


101
NPHETLDAQD PSFQESKRRH IARVGMMAAF AITAHNFPEG LATFFATLEN


 


151
PAVGMPLALA IAIHNIPEGI SIAAPVYFAT RSRKKTVWAC LLSGLAEPLG


 


201
AALGYLVLQP FLSPAVFGSV FGVIAGVMVF LALDELLPAA KRYSDGHETV


 


251
YGLTMGMAVI AVSLVLFHF*






m901/a901 98.9% identity in 269 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2709>:










g902.seq




1
ATGCCGTCCG AACCCGAACG GCGGCATGGC AATACTGCCC TACCCTTCCC


 


51
GATAGCCGCA CGCCCAACGG TCGGTTTTTC CGGCAAGCCT TTCAAGATAA


 


101
CCGGCAAGTG TGTCGTATTG CGCCGCCGCA TTGTCCAAGC GGTTGATTTC


 


151
ACGCCGCGCC TGTTCGCCGT CGGGCATTTC GCCGATGTAC CAGCCTATGT


 


201
GTTTGCGTGC GATGCGCACA CCGACGGTCT CACCATAAAA CGCGTGCATG


 


251
GCGCGGATGT GGTTCAAAAT GGCGGCTCTG CATTCTGCCA AACTCAAGGC


 


301
AGGCGGTAAA ACGCCGTGTT CGGCATAATG CTTCAAATCG CGGAAAAACC


 


351
ACGGCCTGCC TTGCGCGCCG CGCCCTATCA TGATGCCGTC GGCGGCGGTT


 


401
TGTTTGAGGA cggCGGCGGC TTTTTgcggc GAagtGATGT CGCCGTTGac


 


451
cCaggCCGGG ATGTTCAGAc ggCTTTTGGT CTCGGcgatg agttCGTAAC


 


501
gcGCCTCGCC TTTGTACATT TGCGTGcgcG CGcgcccgtg aacggcaaGg


 


551
gcggcaatgc cgcaatcttc ggcgattttg gcgacggcgG gcaggttttg


 


601
atcgtcgtcg tgccaaccca AacggGTTTT GaggGTAACG GGTAcgcCCG


 


651
CCGCCTTgac caccgcctcc aAAatggcGg caaccagcgg CTCGTCCTGC


 


701
ATCagcGCGC TACCGGCTTG GACGTTGCAC ACTTTCttgg cgggGCAGCC


 


751
CATAttgATG TCGATGACCT GCGCCCCGAG TCCGACGTTg taacgcgccg


 


801
catCCGCCAT CtgttcggGG TCGCTGCCGG CAATCTGCAC GGCAACGATG


 


851
CCGccttcat cggcaAAAtc actgcggtgc aGGGTTTTTC CGGTATTCCT


 


901
GAGCGTCGGA TCGCTGGCCA GCATTTCGCA CACCGCCCAA CCTGCGCCAA


 


951
ACGCCCGACA GAGGCGGCGG AAGGGTTTGT CGGCAATGCC CGCCATCGGC


 


1001
GCAAGTGCGA TGGGGTTGTC GATAAAATAA CCGCCGATGT GCATAATGGG


 


1051
CCCGCGTTTC AAAAAAGTGC GCCATTGTAC ATTTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2710; ORF 902.ng>:










g902.pep




1
MPSEPERRHG NTALPFPIAA RPTVGFSGKP FKITGKCVVL RRRIVQAVDF


 


51
TPRLFAVGHF ADVPAYVFAC DAHTDGLTIK RVHGADVVQN GGSAFCQTQG


 


101
RR*NAVFGIM LQIAEKPRPA LRAAPYHDAV GGGLFEDGGG FLRRSDVAVD


 


151
PGRDVQTAFG LGDEFVTRLA FVHLRARAPV NGKGGNAAIF GDFGDGGQVL


 


201
IVVVPTQTGF EGNGYARRLD HRLQNGGNQR LVLHQRATGL DVAHFLGGAA


 


251
HIDVDDLRPE SDVVTRRIRH LFGVAAGNLH GNDAAFIGKI TAVQGFSGIP


 


301
ERRIAGQHFA HRPTCAKRPT EAAEGFVGNA RHRRKCDGVV DKITADVHNG


 


351
PAFQKSAPLY IF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2711>:










m902.seq




1
TTGCACTTTC AAAGGATAAT CAAGTGTTCA GAAGGCATTT GGGCGGTAGG


 


51
CGCACGCCCA ACTGTCGGTT TTTTCGGCAA GTCTTTCAAG ATAACCTGCA


 


101
AGCATGTCGT ATTGCGCCGC CGCACTGTCC AAGCGGTTGA TTTCACGACG


 


151
TgTCTgTTCG CCGTcGGGCA TTTCGTCGAT GTACCAGCCT ATGTGTTTGC


 


201
GTGCGATGCG CACACCGGCG GTGTCGCCGT AAAACGCGTG TATGGCGCGG


 


251
ATGTGGTTCA AAATAGCGGC GGCGCATTCT GCCAAACTCA AGGCAGGCGG


 


301
CAAAACACCG TGTTCGGCAT AATGTTTCAA ATCGCGGAAG AACCACGGCC


 


351
TGCCTTGCGC GCCGCGCCCT ATCATAATGC CGTCGGCGGC GGTTTGTTTG


 


401
AGGACGGCTT GGGCTTTTTG CGGCGAAGTA ATGTCGCCGT TGACCCAGAC


 


451
CGGGATGTTC AGACGGCATT TGGTTTCGGC GATGAGTTCG TAACGCGCTT


 


501
CGCCTTTGTA CATTTGCGTA CGCGTGCGTC CGTGGACGGC AAGGGCGGCG


 


551
ATGCCGCAAT CTTCGGCGAT TTTGGCGATG ACGGGCAGGT TTTGATGGTC


 


601
GTCGTGCCAA CCCAAACGGG TTTTGAGGGT AACGGGTACG CCTGCCGCAC


 


651
GGACGACGGC TTCCAAAATG GCGGCAACCA GCGGCTCGTT CTGCATCAGC


 


701
GCGCTACCGG CTTGGACATT GCAGACTTTT TTAGCGGGAC AGCCCATGTT


 


751
GATGTCGATA AGCTGCGCCC CAAGGCTGAC GTTGTAACGC GCGGCATCCG


 


801
CCATCTGCTG CGGATCGCTT CCGGCAATCT GCACGGCAAC AATGCCGCCT


 


851
TCATCGGCAA AATCGCTGCG GTGCAAGGTT TTTCTAGTAT TTCTGAGCGT


 


901
CGGGTCGCTG GTCAGCATTT CGCACACCGC CCAACCTGCG CCAAAATCTC


 


951
GGCAAAGTCG GCGGAACGGT TTGTCGGTAA TGCCCGCCAT CGGcGCaAGT


 


1001
GCGATGGGGT TGTCGATAAA ATAGCCGCCG ATGTGCATAA TGGATCCGCG


 


1051
TTTCAAAAAA GTACGCCATT GTACATTTTT TAA






This corresponds to the amino acid sequence <SEQ ID 2712; ORF 902>:










m902.pep




1
LHFQRIIKCS EGIWAVGARP TVGFFGKSFK ITCKHVVLRR RTVQAVDFTT


 


51
CLFAVGHFVD VPAYVFACDA HTGGVAVKRV YGADVVQNSG GAFCQTQGRR


 


101
QNTVFGIMFQ IAEEPRPALR AAPYHNAVGG GLFEDGLGFL RRSNVAVDPD


 


151
RDVQTAFGFG DEFVTRFAFV HLRTRASVDG KGGDAAIFGD FGDDGQVLMV


 


201
VVPTQTGFEG NGYACRTDDG FQNGGNQRLV LHQRATGLDI ADFFSGTAHV


 


251
DVDKLRPKAD VVTRGIRHLL RIASGNLHGN NAAFIGKIAA VQGFSSISER


 


301
RVAGQHFAHR PTCAKISAKS AERFVGNARH RRKCDGVVDK IAADVHNGSA


 


351
FQKSTPLYIF *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 902 shows 80.9% identity over a 345 aa overlap with a predicted ORF (ORF 902.ng) from N. gonorrhoeae: 

m902/g902





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2713>:










a902.seq




1
TTGCACTTTC AAAGGATAAT CAAGTGTTCA GAAGGCATTT GGGCGGTAGG


 


51
CGCACGCCCA ACTGTCGGTT TTTTCGGCAA GTCTTTCAAG ATAACCTGCA


 


101
AACATGTCGT ATTGCGCCGC CGCACTGTCC AAGCGGTTGA TTTCACGACG


 


151
TGTCTGTTCG CCGTCGGGCA TTTCGTCGAT GTACCAGCCT ATGTGTTTGC


 


201
GTGCGATGCG CACACCGGCG GTGTCGCCGT AAAACGCGTG CATGGCTCGG


 


251
ATGTGGTTCA AAATAGTGGC GGTACATTCT GCCAAACTCA AGGCAGGCGG


 


301
TAAAACACCG TGTTCGGCGT AATGTTTCAA ATCGCGGAAG AACCACGGTC


 


351
TGCCTTGCGC GCCGCGCCCT ATCATAATGC CGTCTGCGGC GGTTTGTTTG


 


401
AGGACGGCTT GGGCTTTTTG CGGCGAGGTA ATGTCGCCGT TGACCCAGAC


 


451
CGGGATGTTC AGACGGCATT TGGTTTCGGC AATCAGGTCG TAAGCCGCTT


 


501
CGCCTTTGTA CATTTGCGTG CGCGTGCGTC CGTGGACGGC AAGGGCGGCA


 


551
ATGCCGCAAT CTTCGGCGAT TTTGGCGATG ACGGGCAGGT TTTGATGGTC


 


601
GTCGTGCCAA CCCAAACGGG TTTTGAGGGT AACGGGTACG CCCGCCGCTT


 


651
TGACCACCGC CTCCAAAATG GCGGCAACCA GCGGCTCGTT CTGCATCAGC


 


701
GCGCTACCGG CTTGGACATT GCAGACTTTT TTAGCGGGAC AGCCCATGTT


 


751
GATGTCGATA AGCTGCGCCC CAAGGCTGAC GTTGTAACGC GCGGCATCCG


 


801
CCATCTGCTG CGGATCGCTT CCGGCAATCT GCACGGCAAC AATGCCGCCT


 


851
TCATCGGCAA AATCGCTGCG GTGCAAGGTT TTTCTAGTAT TTCTGAGCGT


 


901
CGGGTCGCTG GTCAGCATTT CGCACACCGC CCAACCTGCG CCAAAATCTC


 


951
GGCAAAGTCG GCGGAACGGT TTGTCGGTAA TGCCCGCCAT CGGCGCAAGT


 


1001
GCGATGGGGT TGTCGATAAA ATAGCCGCCG ATGTGCATAA TGGATCCGCG


 


1051
TTTCAAAAAA GTACGCCATT GTACATTTTT TAA






This corresponds to the amino acid sequence <SEQ ID 2714; ORF 902.a>:










a902.pep




1
LHFQRIIKCS EGIWAVGARP TVGFFGKSFK ITCKHVVLRR RTVQAVDFTT


 


51
CLFAVGHFVD VPAYVFACDA HTGGVAVKRV HGSDVVQNSG GTFCQTQGRR


 


101
*NTVFGVMFQ IAEEPRSALR AAPYHNAVCG GLFEDGLGFL RRGNVAVDPD


 


151
RDVQTAFGFG NQVVSRFAFV HLRARASVDG KGGNAAIFGD FGDDGQVLMV


 


201
VVPTQTGFEG NGYARRFDHR LQNGGNQRLV LHQRATGLDI ADFFSGTAHV


 


251
DVDKLRPKAD VVTRGIRHLL RIASGNLHGN NAAFIGKIAA VQGFSSISER


 


301
RVAGQHFAHR PTCAKISAKS AERFVGNARH RRKCDGVVDK IAADVHNGSA


 


351
FQKSTPLYIF *






m902/a902 94.7% identity in 360 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2715>:










g903.seq




1
ATGGCAACAC AGGTAGGCGG TGCAAattcG gatgaggCAA GCCCCTGCTT


 


51
TCCTATTTCT GAGGTGGAaT TGGTGGGTGA aGaaacggct aAATTCCGgt


 


101
tTGCGCTcaa ccaTGCCTTG tgccAAACAC ATTTTGtttc cGgcaagtgt


 


151
CTGcATGcgg gcgacatTAA TCAAAtcaTG TCCTTAGCAC AAAATGCTTT


 


201
GATCGGCAGG GGATATACCA CGACCCGTAT CTTGGCTGCG CCACAGGATT


 


251
TGAATAGTGG caaGCTTCAA TTAAccctga tgccggGCTA TCtgcgctcC


 


301
ATAcgaATCG atcggtccaa cgatgatcaa ACCCATgcAG GACGTATTGC


 


351
AGCATTCCAA AACAAATTTC CCACCCGCTC GAACGATCTG TTGAATCTGC


 


401
GTGATTTGGA ACAAGGACTG GAAAATCTCA AATGTCTCCC GACTGCGGAA


 


451
GCCGATCTCC AAATCgttcc cgtaGAGAGA GAACcAAACC AAAGTGATGT


 


501
CGTGGTGCAA TGGCGGTAAC GTCTGCTGCC CTACTGTGTG AGTGTGGGGA


 


551
TGGATAATTC GGGTAGTGAG GCGACAGGAA AATACCAAGG AAATATCACT


 


601
TTCTCTGCCG ACAATCCTTT TggactgAGT GATATGTTCT ATGTAAATTA


 


651
TGGACGTTCA ATTGGCGGTA CGcccgATGA GGAAAATTTT GACGGCCATC


 


701
GCAAAGAAGG CGGATCAAAC AATTACGCCG TACATTATTC AGCCCCTTTC


 


751
GGTAAATGGA CATGGGCATT CAATCACAAT GGCTACCGTT ACCATCAGGC


 


801
GGTTTCCGGA TTATCGGAAG TCTATGACTA TAATGGAAAA AGTTACAACA


 


851
CTGATTTCGG CTTCAACCGC CTGTTGTATC GTGATGCCAA ACGCAAAACC


 


901
TATCTCAGTG TAAAACTGTG GACGAGGGAA ACAAAAAGTT ACATTGATGA


 


951
TGCCGAACTG ACTGTACAAC GGCGTAAAAC CACAGGTTGG TTGGCAGAAC


 


1001
TTTCCCACAA AGGATATATC GGTCGCAGTA CGGCAGATTT TAAGTTGAAA


 


1051
TATAAACACG GCACCGGCAT GAAAGATGCT CTGCGCGCGC CTGAAGAAGC


 


1101
CTTTGGCGAA GGCACGTCAC GTATGAAAAT TTGGACGGCA TCGGCTGATG


 


1151
TAAATACTCC TTTTCAAATC GGTAAACAGC TATTTGCCTA TGACACATCC


 


1201
GTTCATGCAC AATGGAACAA AACCCCGCTA ACATCGCAAG ACAAACTGGC


 


1251
TATCGGCGGA CACCACACCG TACGTGGCTT CGACGGTGAA ATGAGTTTGC


 


1301
CTGCCGAGCG GGGATGGTAT TGGCGCAACG ATTTGAGCTG GCAATTTAAA


 


1351
CCAGGCCATC AGCTTTATCT TGGGGCTGAT GTAGGACATG TTTCAGGACA


 


1401
ATCCGCCAAA TGGTTATCGG GCCAAACTCT AGCCGGCACA GCAATTGGGA


 


1451
TACGCGGGCA GATAAAGCTT GGCGGCAACC TGCATTACGA TATATTTACC


 


1501
GGCCGTGCAT TGAAAAAGCC cgaatatttt cAGACGAAGA Aatgggtaac


 


1551
ggggtTTCAG gtgggttatt cgTTTTGA






This corresponds to the amino acid sequence <SEQ ID 2716; ORF 903.ng>:










g903.pep




1
MATQVGGANS DEASPCFPIS EVELVGEETA KFRFALNHAL CQTHFVSGKC


 


51
LHAGDINQIM SLAQNALIGR GYTTTRILAA PQDLNSGKLQ LTLMPGYLRS


 


101
IRIDRSNDDQ THAGRIAAFQ NKFPTRSNDL LNLRDLEQGL ENLKCLPTAE


 


151
ADLQIVPVER EPNQSDVVVQ WRXRLLPYCV SVGMDNSGSE ATGKYQGNIT


 


201
FSADNPFGLS DMFYVNYGRS IGGTPDEENF DGHRKEGGSN NYAVHYSAPF


 


251
GKWTWAFNHN GYRYHQAVSG LSEVYDYNGK SYNTDFGFNR LLYRDAKRKT


 


301
YLSVKLWTRE TKSYIDDAEL TVQRRKTTGW LAELSHKGYI GRSTADFKLK


 


351
YKHGTGMKDA LRAPEEAFGE GTSRMKIWTA SADVNTPFQI GKQLFAYDTS


 


401
VHAQWNKTPL TSQDKLAIGG HHTVRGFDGE MSLPAERGWY WRNDLSWQFK


 


451
PGHQLYLGAD VGHVSGQSAK WLSGQTLAGT AIGIRGQIKL GGNLHYDIFT


 


501
GRALKKPEYF QTKKWVTGFQ VGYSF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2717>:










m903.seq




1
ATGCAGCGTC AGCAGCACAT AGATGCTGAA TTGTTAACTG ATGCAAATGT


 


51
CCGTTTCGAG CAACCATTGG AGAAGAACAA TTATGTCCTG AGTGAAGATG


 


101
AAACACCGTG TACTCGGGTA AATTACATTA GTTTAGATGA TAAGACGGTG


 


151
CGCAAATTTT CTTTTCTTCC TTCTGTGCTC ATGAAAGAAA CAGCTTTTAA


 


201
AACTGGGATG TGTTTAGGTT CCAATAATTT GAGCAGGCTA CAAAAAGCCG


 


251
CGCAACAGAT ACTGATCGTG CGTGGCTACC TCACTTCCCA AGCTATTATC


 


301
CAaCCACAGA ATATGGATTC GGGAATTCTG AAATTACGGG TATCAGCAGG


 


351
CGAAATAGGG GATATCCGCT ATGAAGAAAA ACGGGATGGG AAGTCTGCCG


 


401
AGGGCAGTAT TAGTGCATTC AATAACAAAT TTCCCTTATA TAGGAACAAA


 


451
ATTCTCAATC TTCGCGATGT AGAGCAGGGC TTGGAAAACC TGCGTCGTTT


 


501
GCCGAGTGTT AAAACAGATA TTCAGATTAT ACCGTCCGAA GAAGAAGGCA


 


551
AAAGCGATTT ACAGATCAAA TGGCAGCAGA ATAAACCCAT ACGGTTCAGT


 


601
ATCGGTATAG ATGATGCGGG CGGCAAAACG ACCGGCAAAT ATCAAGGAAA


 


651
TGTCGCTTTA TCGTTCGATA ACCCTTTGGG CTTAAGCGAT TTGTTtTATG


 


701
TTTCATATGG ACGCGGTTTG GCGCACAAAA CGGACTTGAC TGATGCCACC


 


751
GGTACGGAAA CTGAAAGCGG ATCCAGAAGT TACAGCGTGC ATTATTCGGT


 


801
GCCCGTAAAA AAATGGCTGT TTTCTTTTAA TCACAATGGA CATCGTTACC


 


851
ACGAAGCAAC CGAAGGCTAT TCCGTCAATT ACGATTACAA CGGCAAACAA


 


901
TATCAGAGCA GCCTGGCCGC CGAGCGCATG CTTTGGCGTA ACAGACTTCA


 


951
TAAAACTTCA GTCGGAATGA AATTATGGAC ACGCCAAACC TATAAATACA


 


1001
TCGACGATGC CGAAATCGAA GTACAACGCC GCCGCTCTGC AGGCTGGGAA


 


1051
GCCGAATTGC GCCACCGTGC TTACCTCAAC CGTTGGCAGC TTGACGGCAA


 


1101
GTTGTCTTAC AAACGCGGGA CCGGCATGCG CCAAAGTATG CCTGCACCGG


 


1151
AAGAAAACGG CGGCGATATT CTTCCAGGTA CATCTCGTAT GAAAATCATT


 


1201
ACTGCCAGTT TGGACGCAGC CGCCCCATTT AyTTTAGGCA AACAGCAGTT


 


1251
TTTCTACGCA ACCGCCATTC AAGCTCAATG GAACAAAACG CCGTTGGTTG


 


1301
CCCAAGATAA ATTGTCAATC GGCAGCCGCT ACACCGTTCG CGGATTTGAT


 


1351
GGGGAGCAGA GTCTTTTCGG AGAGCGAGGT TTCTACTGGC AGAATACTTT


 


1401
AACTTGGTAT TTTCATCCGA ACCATCAGTT CTATCTCGGT GCGGACTATG


 


1451
GCCGCGTATC TGGCGAAAGT GCACAATATG TATCGGGCAA GCAGCTGATG


 


1501
GGTGCAGTGG TCGGCTTCAG AGGAGGGCAT AAAGTAGGCG GTATGTTTGC


 


1551
TTATGATCTG TTTGCCGGCA AGCCGCTTCA TAAACCCAAA GGCTTTCAGA


 


1601
CGACCAACAC CGTTTACGGC TTCAACTTGA ATTACAGTTT CTAA






This corresponds to the amino acid sequence <SEQ ID 2718; ORF 903>:










m903.pep




1
MQRQQHIDAE LLTDANVRFE QPLEKNNYVL SEDETPCTRV NYISLDDKTV


 


51
RKFSFLPSVL MKETAFKTGM CLGSNNLSRL QKAAQQILIV RGYLTSQAII


 


101
QPQNMDSGIL KLRVSAGEIG DIRYEEKRDG KSAEGSISAF NNKFPLYRNK


 


151
ILNLRDVEQG LENLRRLPSV KTDIQIIPSE EEGKSDLQIK WQQNKPIRFS


 


201
IGIDDAGGKT TGKYQGNVAL SFDNPLGLSD LFYVSYGRGL AHKTDLTDAT


 


251
GTETESGSRS YSVHYSVPVK KWLFSFNHNG HRYHEATEGY SVNYDYNGKQ


 


301
YQSSLAAERM LWRNRLHKTS VGMKLWTRQT YKYIDDAEIE VQRRRSAGWE


 


351
AELRHRAYLN RWQLDGKLSY KRGTGMRQSM PAPEENGGDI LPGTSRMKII


 


401
TASLDAAAPF XLGKQQFFYA TAIQAQWNKT PLVAQDKLSI GSRYTVRGFD


 


451
GEQSLFGERG FYWQNTLTWY FHPNHQFYLG ADYGRVSGES AQYVSGKQLM


 


501
GAVVGFRGGH KVGGMFAYDL FAGKPLHKPK GFQTTNTVYG FNLNYSF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 903 shows 48.9% identity over a 519 as overlap with a predicted ORF (ORF 903.ng) from N. gonorrhoeae: 

m903/g903




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2719>:










a903.seq




1
ATGCAGCGTC AGCAGCACAT AGATGCTGAA TTGTTAACTG ATGCAAATGT


 


51
CCGTTTCGAG CAACCATTGG AGAAGAACAA TTATGTCCTG AGTGAAGATG


 


101
AAACACCGTG TACTCGGGTA AATTACATTA GTTTAGATGA TAAGACGGCG


 


151
CGCAAATTTT CTTTTCTTCC TTCTGTGCTC ATGAAAGAAA CAGCTTTTAA


 


201
AACTGGGATG TGTTTAGGTT CCAATAATTT GAGCAGGCTA CAAAAAGCCG


 


251
CGCAACAGAT ACTGATTGTG CGTGGCTACC TCACTTCCCA AGCTATTATC


 


301
CAACCACAGA ATATGGATTC GGGAATTCTG AAATTACGGG TATCAGCAGG


 


351
CGAAATAGGG GATATCCGCT ATGAAGAAAA ACGGGATGGG AAGTCTGCCG


 


401
AGGGCAGTAT TAGTGCATTC AATAACAAAT TTCCCTTATA TAGGAACAAA


 


451
ATTCTCAATC TTCGCGATGT AGAGCAGGGC TTGGAAAACC TGCGTCGTTT


 


501
GCCGAGTGTT AAAACAGATA TTCAGATTAT ACCGTCCGAA GAAGAAGGCA


 


551
AAAGCGATTT ACAGATCAAA TGGCAGCAGA ATAAACCCAT ACGGTTCAGT


 


601
ATCGGTATAG ATGATGCGGG CGGCAAAACG ACCGGCAAAT ATCAAGGAAA


 


651
TGTCGCTTTA TCGTTCGATA ACCCTTTGGG CTTAAGCGAT TTGTTTTATG


 


701
TTTCATATGG ACGCGGTTTG GTGCACAAAA CGGACTTGAC TGATGCCACC


 


751
GGTACGGAAA CTGAAAGCGG ATCCAGAAGT TACAGCGTGC ATTATTCGGT


 


801
GCCCGTAAAA AAATGGCTGT TTTCTTTTAA TCACAATGGA CATCGTTACC


 


851
ACGAAGCAAC CGAAGGCTAT TCCGTCAATT ACGATTACAA CGGCAAACAA


 


901
TATCAGAGCA GCCTGGCCGC CGAGCGCATG CTTTGGCGTA ACAGGTTTCA


 


951
TAAAACTTCA GTCGGAATGA AATTATGGAC ACGCCAAACC TATAAATACA


 


1001
TCGACGATGC CGAAATCGAA GTGCAACGCC GCCGCTCTGC AGGCTGGGAA


 


1051
GCCGAATTGC GCCACCGTGC TTACCTCAAC CGTTGGCAGC TTGACGGCAA


 


1101
GTTGTCTTAC AAACGCGGGA CCGGCATGCG CCAAAGTATG CCCGCACCTG


 


1151
AAGAAAACGG CGGCGGTACT ATTCCAGGCA CATCCCGTAT GAAAATCATA


 


1201
ACCGCCGGAT TGGATGCAGC GGCCCCGTTT ATGTTGGGCA AACAGCAGTT


 


1251
TTTCTACGCA ACCGCCATTC AAGCTCAATG GAACAAAACG CCTTTGGTTG


 


1301
CCCAAGACAA GTTGTCTATC GGCAGCCGCT ACACCGTTNG CGGATTTGAT


 


1351
GGGGAGCAGA GTCTTTTCGG AGAGCGAGGT TTCTACTGGC AGAATACTTT


 


1401
AACTTGGTAT TTTCATCCGA ACCATCAGTT CTATCTCGGT GCGGACTATG


 


1451
GCCGCGTATC TGGCGAAAGT GCACAATATG TATCGGGCAA GCAGCTGATG


 


1501
GGTGCAGTGG TCGGNTTCAG AGGAGGNCAT AAAGTAGGCG GTATGTTTGC


 


1551
TTATGATCTG TTTGCCGGCA AGCCGCTTCA TAAACCCAAA GGCTTTCAGA


 


1601
CGACCAACAC CGTTTACGGC TTCAACTTGA ATTACAGTTT CTAA






This corresponds to the amino acid sequence <SEQ ID 2720; ORF 903.a>:










a903.pep




1
MQRQQHIDAE LLTDANVRFE QPLEKNNYVL SEDETPCTRV NYISLDDKTA


 


51
RKFSFLPSVL MKETAFKTGM CLGSNNLSRL QKAAQQILIV RGYLTSQAII


 


101
QPQNMDSGIL KLRVSAGEIG DIRYEEKRDG KSAEGSISAF NNKFPLYRNK


 


151
ILNLRDVEQG LENLRRLPSV KTDIQIIPSE EEGKSDLQIK WQQNKPIRFS


 


201
IGIDDAGGKT TGKYQGNVAL SFDNPLGLSD LFYVSYGRGL VHKTDLTDAT


 


251
GTETESGSRS YSVHYSVPVK KWLFSFNHNG HRYHEATEGY SVNYDYNGKQ


 


301
YQSSLAAERM LWRNRFHKTS VGMKLWTRQT YKYIDDAEIE VQRRRSAGWE


 


351
AELRHRAYLN RWQLDGKLSY KRGTGMRQSM PAPEENGGGT IPGTSRMKII


 


401
TAGLDAAAPF MLGKQQFFYA TAIQAQWNKT PLVAQDKLSI GSRYTVXGFD


 


451
GEQSLFGERG FYWQNTLTWY FHPNHQFYLG ADYGRVSGES AQYVSGKQLM


 


501
GAVVGFRGGH KVGGMFAYDL FAGKPLHKPK GFQTTNTVYG FNLNYSF*






m903/a903 98.4% identity in 547 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2721>:










g904.seq




1
ATGATGCAGC ACAATCGTTT CTTCGCGGTC GGGGCCGGTg gaGACGATGG


 


51
CGACCGGCGC GCCGCAGACT TCTTCAATCC GTTTCAAATA TGCTTTGGCA


 


101
TTGGCAGGCA ATGCGTCGTA GCTTTTCACG CCGACAGTCG ATTCGCGCCA


 


151
GCCGGGCATG GTTTCGTAAA TCGGTTTGCA GGTTTCCACC GCATCCGAAC


 


201
CGCAAGGCAG GATGTCGGTT TTGCCGCCGC CTGGCAATTC GTAGCCGACG


 


251
CAGATATTGA TGGTTTCAAC GCCGTCCATT ACATCGAGTT TGGTAATGCA


 


301
CATACCGGAA ATGCCGTTGA TTTGGATGGA GCGTTTCAGG GCGGCGGCAT


 


351
CAAACCAGCC GCAGCGGCGC GCGCGGCCGG TTACCGAACC GAATTCGTGT


 


401
CCGCGCTCCG CCAAACCTGC GCCTACTTCG TCGAACAATT CGGTCGGGAA


 


451
CGGGCCCGAA CCGACGCGCG TGGTATAGGC TTTGACGATG CCCAAAACAT


 


501
AATCCAGCAT TTGAGGACCT ACGCCCGCGC CTGCCGAAGC CGCGCCGGCG


 


551
AGACAGTTGG ACGAGGTAAC GAAGGGGTAA GTGCCGTAGT CGATGTCCAA


 


601
CAACGCACCT TGCGCGCCTT CAAACAGCAG TTTTTCGCCG TTTTTGTTTT


 


651
TTTCGTTCAA CACGCgggaC acgtcgGCAA TCATCGGCGC AATGCGCGGC


 


701
GCGACTTTTT CGATAACCGC CATCACGTCT TCCGCTTTAA CCGGTCCGGC


 


751
GTTATGCAGG TATTGGAGTT GGACGTTGTA ATAGGCAAGG ACGGCATCCA


 


801
GTTTTTCACG CAGTTTTTCA GGATGCAGCA AATCGGCGGC GCGAATGGCG


 


851
CGGCGTGCCA CTTTGTCTTC GTAGGCAGGG CCGATGCCGC GGCCGGTCGT


 


901
GCCGATTTTG CCTTTGCCGC GCGATGCTTC GCGGGCTTGG TCGAGCGCGA


 


951
TGTGGTAAGG CAGGATCAGC GGGCAGGTCG GCGCGATTTT CAGACGGCCT


 


1001
TCGACGTTTT TCACGCCTGC CGCGTTCAAC TCGTCGATTT CGCCCAACAG


 


1051
GGCTTCGGGg gaaacgAcaa cGCCCGAACC gatGAAGCAA TCCAATCCTT


 


1101
CGTGCAGGAT ACCGCTCGGA ATCAGGCGCA AAATGGTTTT TTTGCCGCCG


 


1151
ACGACCAAGG TATGGCCCGC ATTGTGGCCG CCTTGGAAGC GCACgacGct


 


1201
gCCGGCTTCT TCCGCCAGCC AGTCAACGAT TTTACCTTTA CCCTCGTCGC


 


1251
CCCACTGTgc gccGATTACT ACAACATTTT TAGCCATAGC CATATAACCT


 


1301
ATCGatatTA A






This corresponds to the amino acid sequence <SEQ ID 2722; ORF 904.ng>:










g904.pep




1
MMQHNRFFAV GAGGDDGDRR AADFFNPFQI CFGIGRQCVV AFHADSRFAP


 


51
AGHGFVNRFA GFHRIRTARQ DVGFAAAWQF VADADIDGFN AVHYIEFGNA


 


101
HTGNAVDLDG AFQGGGIKPA AAARAAGYRT EFVSALRQTC AYFVEQFGRE


 


151
RARTDARGIG FDDAQNIIQH LRTYARACRS RAGETVGRGN EGVSAVVDVQ


 


201
QRTLRAFKQQ FFAVFVFFVQ HAGHVGNHRR NARRDFFDNR HHVFRFNRSG


 


251
VMQVLELDVV IGKDGIQFFT QFFRMQQIGG ANGAACHFVF VGRADAAAGR


 


301
ADFAFAARCF AGLVERDVVR QDQRAGRRDF QTAFDVFHAC RVQLVDFAQQ


 


351
GFGGNDNART DEAIQSFVQD TARNQAQNGF FAADDQGMAR IVAALEAHDA


 


401
AGFFRQPVND FTFTLVAPLC ADYYNIFSHS HITYRY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2723>:










m904.seq




1
ATGATGCAGC ACAATCGTTT CTTCTCGGTC GGGGCCGgTG GAGACGATGG


 


51
CGACCGGCGC GCCGCAGACT TCTTCAATCC GTTTCAAATA TGCTTTGGCG


 


101
TTTTCGGGCA ATGCGCCGTA GTCCTTCACG CCGAAAGTGG ATTCGCGCCA


 


151
GCCGGGCATG GTTTCGTAAA TCGGCTTGCA GGTTTCCACC GCATCGGAAC


 


201
CGCAAGGCAG GATGTCGGTT TTGCCGCCGT CGGGCAATTC ATAGCCGACG


 


251
CAGATATTGA TGGTTTCAAC GCCGTCCATT ACATCGAGTT TAGTAATACA


 


301
CATACCGGAA ATGCCGTTGA TTTGGATGGA GCGTTTCAGG GCGGCGGCAT


 


351
CAAACCAGCC GCAGCGGCGT GCGCGTCCGG TTACCGAACC GAATTCGTGT


 


401
CCGCGTTCTG CCAAACCTAC GCCTACTTCG TCGAACAATT CGGTCGGGAA


 


451
CGGGCCCGAA CCGACGCGCG TGGTATAGGC TTTGACGATG CCCAAAACAT


 


501
AATCCAGCAT TTGAGGACCT ACGCCCGCGC CTGCCGAAGC TGCGCCCGCC


 


551
AGACAGTTGG ACGAGGTAAC GAAGGGATAA GTGCCGTAGT CGATGTCCAA


 


601
CAACGCACCT TGCGCGCCTT CAAACAGCAG TTTTTCGCCG TTTTTGTTTT


 


651
TCTCGTTCAA CACGCGGGAC ACGTCGGTAA TCATCGGCGC AATGCGCGGC


 


701
GCGACTTTTT CGATAACCGC CATCACGTCT TCCGCTTTAA CCGGCTCGGC


 


751
ATTGTGCAGA TGTTGCAGTT GGACATTGTA ATAGGCAAGG ACGGCATCCA


 


801
GTTTTTCACG CAGTTTyTCA GGATGCAGCA AATCGGCGGC GCGAATGGCG


 


851
CGGCGTGCCA CTTTGTCTTC GTAGGCAGGG CCGATGCCGC GGCCGGTCGT


 


901
GCCGATTTTG CCTTTGCCGC GCG.ATcTTC GCGGGCTTGG TCGAGCGCGA


 


951
TGTGGTAAGG CAGGATCAGC GGGCAGGTCG GCGCGATTTT CAGACGGCCT


 


1001
TCGACGTTTT TCACGCCTGC CGCGTTCAAC TCGTCGATTT CGCCCAACAG


 


1051
GGCTTCGGGG GAGACGACAA CGCCCGAACC GATGAAGCAG TCCAAACTTT


 


1101
CATGCAGGAT GCCGCTCGGA ATCAGGCGCA AAATGGTTTT TTTGCCGCCG


 


1151
ACAACCAAGG TATGGCCCGC ATTGTGGCCG CCTTGGAAGC GCACCaCGCC


 


1201
GCCGGCTTCT TCCGCCAGCC AGTCAACGAT TTTACCTTTA CCCTCGTCGC


 


1251
CCCACTGTGC GCCGATTAsT ACAACATTTT TAGCCATAGC CATATAACCT


 


1301
ATCGATATTA A






This corresponds to the amino acid sequence <SEQ ID 2724; ORF 904>:










m904.pep




1
MMQHNRFFSV GAGGDDGDRR AADFFNPFQI CFGVFGQCAV VLHAESGFAP


 


51
AGHGFVNRLA GFHRIGTARQ DVGFAAVGQF IADADIDGFN AVHYIEFSNT


 


101
HTGNAVDLDG AFQGGGIKPA AAACASGYRT EFVSAFCQTY AYFVEQFGRE


 


151
RARTDARGIG FDDAQNIIQH LRTYARACRS CARQTVGRGN EGISAVVDVQ


 


201
QRTLRAFKQQ FFAVFVFLVQ HAGHVGNHRR NARRDFFDNR HHVFRFNRLG


 


251
IVQMLQLDIV IGKDGIQFFT QFXRMQQIGG ANGAACHFVF VGRADAAAGR


 


301
ADFAFAAXIF AGLVERDVVR QDQRAGRRDF QTAFDVFHAC RVQLVDFAQQ


 


351
GFGGDDNART DEAVQTFMQD AARNQAQNGF FAADNQGMAR IVAALEAHHA


 


401
AGFFRQPVND FTFTLVAPLC ADXYNIFSHS HITYRY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 904 shows 90.4% identity over a 436 as overlap with a predicted ORF (ORF 904.ng) from N. gonorrhoeae: 

m904/g904




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2725>:










a904.seq




1
ATGATGCAGC ACAATCGTTT CTTCGCGGTC GGGGCCGGTG GAGACGATGG


 


51
CGACCGGCGC ACCGCAGACT TCTTCAATCC GTTTCAAATA TGCTTTGGCA


 


101
TTGGCAGGTA ATGCGTCGTA GCTTTTCACG CCGAAAGTGG ATTCGCTCCA


 


151
ACCGGGCATG GTTTCGTAAA TCGGCTTGCA GGCTTCTACC GCATCAGAGC


 


201
CGCAAGGCAG GATGTCGGTT TTGCCGCCGT CGGGCAATTC GTAGCCGACG


 


251
CAGATATTGA TGGTTTCAAC GCCGTCCATT ACATCGAGTT TGGTAATACA


 


301
CATACCGGAA ATGCCGTTGA TTTGGATGGA GCGTTTCAGG GCGGCGGCAT


 


351
CAAACCAGCC GCAGCGGCGT GCGCGTCCGG TTACCGAACC GAATTCGTGT


 


401
CCGCGTTCTG CCAAACCTGC TCCGACTTCG TCGAACAATT CGGTCGGGAA


 


451
CGGGCCCGAA CCGACGCGCG TGGTATAGGC TTTGACGATG CCCAAAACAT


 


501
AATCCAGCAT TTGAGGGCCT ACGCCCGCGC CTGCCGAAGC CGCGCCGGCG


 


551
AGGCAGTTGG ACGAAGTAAC GAAGGGGTAA GTGCCGTAGT CGATGTCCAA


 


601
CAACGCACCT TGCGCGCCTT CAAACAGCAG TTTTTCGCCG TTTTTGTTTT


 


651
TTTCGTTCAA CACGCGGGAC ACGTCGGTAA TCATCGGCGT AATGCGCGGC


 


701
GCGACTTTTT CGATAACCGC CATCACGTCT TCCGCTTTCA CCGACTCGGC


 


751
ATTGTGCAGA TGTTGCAGTT GGACGTTGTA ATAAGCAAAG ACGGCATCCA


 


801
GTTTTTCACG CAGTTTTTCA GGATGCAGCA AATCGGCGGC GCGAATGGCG


 


851
CGGCGTGCCA CTTTGTCTTC GTAGGCAGGG CCGATGCCGC GGCCGGTCGT


 


901
GCCGATTTTG CCTTTGCCGC GCGATGCTTC TCGGGCTTGG TCGAGCGCGA


 


951
TGTGATAAGG CAGGATCAGC GGGCAGGTCG GCGCGATTTT CAGACGGCCT


 


1001
TCGACGTTTT TCACGCCTGC CGCGTTCAAC TCGTCGATTT CGCCCAACAG


 


1051
GGCTTCGGGG GAGACGACAA CGCCCGAACC GATGAAGCAG TCCAGACTTT


 


1101
CATGCAGGAT GCCGCTCGGA ATCAGGCGCA AAATGGTTTT TTTGCCGCCG


 


1151
ACAACCAAGG TATGACCCGC ATTGTGGCCG CCTTGGAAGC GCACCACGCC


 


1201
TCCGGCTTCT TCCGCCAGCC AGTCAACGAT TTTACCTTTA CCCTCGTCGC


 


1251
CCCACTGTGC GCCGATTACT ACAACATTTT TAGCCATAGC CATATAACCT


 


1301
.TCGATATTA A






This corresponds to the amino acid sequence <SEQ ID 2726; ORF 904.a>:










a904.pep




1
MMQHNRFFAV GAGGDDGDRR TADFFNPFQI CFGIGR*CVV AFHAESGFAP


 


51
TGHGFVNRLA GFYRIRAARQ DVGFAAVGQF VADADIDGFN AVHYIEFGNT


 


101
HTGNAVDLDG AFQGGGIKPA AAACASGYRT EFVSAFCQTC SDFVEQFGRE


 


151
RARTDARGIG FDDAQNIIQH LRAYARACRS RAGEAVGRSN EGVSAVVDVQ


 


201
QRTLRAFKQQ FFAVFVFFVQ HAGHVGNHRR NARRDFFDNR HHVFRFHRLG


 


251
IVQMLQLDVV ISKDGIQFFT QFFRMQQIGG ANGAACHFVF VGRADAAAGR


 


301
ADFAFAARCF SGLVERDVIR QDQRAGRRDF QTAFDVFHAC RVQLVDFAQQ


 


351
GFGGDDNART DEAVQTFMQD AARNQAQNGF FAADNQGMTR IVAALEAHHA


 


401
SGFFRQPVND FTFTLVAPLC ADYYNIFSHS HITXRY*






m904/n904 91 3% identity in 436 aa overlap





g906.seq not found yet

g906.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2727>:










m906.seq




1
ATGAAATATA TCGTATCAAT CTCTCTGGCT ATGGGATTGG CTGCCTGTTC


 


51
GTTTGGGGGA TTTAAACCAA ATCCGTGGGA CGCCGCGTCA TTTTGGGAAT


 


101
TGAAAAATTA CGCCAATCCC TATCCGGGAT CAGCCTCGGC GGCACTTGAC


 


151
CAATATCCAT CGAAAGCAAG ACGAAGGCAA CTGAAAGACA TGCAAGAGTG


 


201
CGGCTATGAC CCAATAGACG GCGGAAAGTC TGAAGCAGAT GCCTGCCTGA


 


251
GGAAAAAAGG CTGGTGTCGT AAGGGTTTCG ACCCTTATCC CGAAAACAAA


 


301
AAATACGAAT GGCCTCGAGA AGAAGGAAAA ACAAAATGA






This corresponds to the amino acid sequence <SEQ ID 2728; ORF 906>:










m906.pep




1
MKYIVSISLA MGLAACSFGG FKPNPWDAAS FWELKNYANP YPGSASAALD


 


51
QYPSKARRRQ LKDMQECGYD PIDGGKSEAD ACLRKKGWCR KGFDPYPENK


 


101
KYEWPREEGK TK*






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2729>:









g907.seq (partial)










1
ATGAAAAAAC CGACCGATAC CCTACCCGTC AATCTgcaAC GCCGCCGCCT



 


51
GCTGTGTGCC GCCGGCGCGC TGTTGATCAG CCCGCTGGCG CACGCCGGCG


 


101
CGCAACGTGA AGAAACGCtt gCCGACGATG TGGCTTCCGT GATGAGGAGT


 


151
TCTGTCGGCA GCGTCAATCC GCCGAGGCTG GTGTTCGACA ATCCGAAAGA


 


201
GGGCGAACGT TGGTTGTCCG CGATGTCGGC ACGTTTGGCA AGATTCGTCC


 


251
CCGACGAGGG GGAGCGGCGC AGGCTGCTGG TCAATATCCA ATACGAAAGC


 


301
AGCCGGGCCG GTTTGGATAC GCAGATTGTG TTGGGGCTGa ttgaagtgga


 


351
aagcgggtac cgagctcgaa tcatatca..






This corresponds to the amino acid sequence <SEQ ID 2730; ORF 907.ng>:









g907.pep (partial)










1
MKKPTDTLPV NLQRRRLLCA AGALLISPLA HAGAQREETL ADDVASVMRS



 


51
SVGSVNPPRL VFDNPKEGER WLSAMSARLA RFVPDEGERR RLLVNIQYES


 


101
SRAGLDTQIV LGLIEVESGY RARIIS...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2731>:










m907.seq




1
ATGAGAAAAC CGACCGATAC CCTACCCGTT AATCTGCAAC GCCGCCGCCT


 


51
GTTGTGTGCC GCCGGTGCGT TGTTGCTCAG TCCTCTGGCG CACGCCGGCG


 


101
CGCAACGTGA GGAAACGCTT GCCGACGATG TGGCTTCCGT GATGAGGAGT


 


151
TCTGTCGGCA GCGTCAATCC GCCGAGGCTG GTGTTTGACA ATCCGAAAGA


 


201
GGGCGAGCGT TGGTTGTCTG CCATGTCGGC ACGTTTGGCA AGGTTCGTCC


 


251
CCGAGGAGGA GGAGCGGCGC AGGCTGCTGG TCAATATCCA GTACGAAAGC


 


301
AGCCGGGCCG GTTTGGATAC GCAGATTGTG TTGGGGCTGA TTGAGGTGGA


 


351
AAGCGCGTTC CGCCAGTATG CAATCAGCGG TGTCGGCGCG CGCGGCCTGA


 


401
TGCAGGTTAT GCCGTTkTGG AAAAACTACA TCGGCAAACC GGCGCACAAC


 


451
CTGTTCGACA TCCGCACCAA CCTGCGTTAC GGCTGTACCA TCCTGCGCCA


 


501
TTACCGGAAT CTTGAAAAAG GCAACATCGT CCGCGCGCTT GCCCGCTTTA


 


551
ACGGCAGCTT GGGCAGCAAT AAATATCCGA ACGCCGTTTT GGgCGCGTGG


 


601
CGCAACCGCT GGCAGTGGCG TTGA






This corresponds to the amino acid sequence <SEQ ID 2732; ORF 907>:










m907.pep




1
MRKPTDTLPV NLQRRRLLCA AGALLLSPLA HAGAQREETL ADDVASVMRS


 


51
SVGSVNPPRL VFDNPKEGER WLSAMSARLA RFVPEEEERR RLLVNIQYES


 


101
SRAGLDTQIV LGLIEVESAF RQYAISGVGA RGLMQVMPXW KNYIGKPAHN


 


151
LFDIRTNLRY GCTILRHYRN LEKGNIVRAL ARFNGSLGSN KYPNAVLGAW


 


201
RNRWQWR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 907 shows 92.9% identity over a 126 aa overlap with a predicted ORF (ORF 907.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2733>:










a907.seq




1
ATGAAAAAAC CGACCGATAC CCTACCCGTC AATCTGCAAC GCCGCCGCCT


 


51
ATTGTGTGCT GCCGGCGCGC TGTTGCTCAG CCCGCTGGCA CAAGCCGGCG


 


101
CGCAACGTGA AGAAACGCTT GCCGACGATG TGGCTTCCGT GATGAGGAGC


 


151
TCTGTCGGCA GCATAAATCC GCCGAGGCTG GTGTTCGACA ATCCGAAAGA


 


201
GGGCGAGCGT TGGCTGTCCG CGATGTCTGC TCGGTTGGCA AGGTTCGTCC


 


251
CCGATGAGGA GGAGCGGCGC AGGCTGCTGG TCAATATCCA GTACGAAAGC


 


301
AGCCGGGCCG GTTTGGATAC GCAGATTGTG TTGGGGCTGA TTGAGGTGGA


 


351
AAGCGCGTTC CGCCAGTATG CAATCAGCGG TGTCGGCGCG CGCGGCCTGA


 


401
TGCAGGTTAT GCCGTTTTGG AAAAACTACA TCGGCAAACC GGCGCACAAC


 


451
CTGTTCGACA TCCGCACCAA CCTGCGTTAC GGCTGTACCA TCCTGCGCCA


 


501
TTACCGGAAT CTTGAAAAAG GCAACATCGT CCGCGCACTC GCCCGTTTTA


 


551
ACGGTAGCCT CGGCAGCAAT AAATATCCGA ACGCCGTTTT GGGCGCGTGG


 


601
CGCAACCGCT GGCAGTGGCG TTGA






This corresponds to the amino acid sequence <SEQ ID 2734; ORF 907.a>:










a907.pep




1
MKKPTDTLPV NLQRRRLLCA AGALLLSPLA QAGAQREETL ADDVASVMRS


 


51
SVGSINPPRL VFDNPKEGER WLSAMSARLA RFVPDEEERR RLLVNIQYES


 


101
SRAGLDTQIV LGLIEVESAF RQYAISGVGA RGLMQVMPFW KNYIGKPAHN


 


151
LFDIRTNLRY GCTILRHYRN LEKGNIVRAL ARFNGSLGSN KYPNAVLGAW


 


201
RNRWQWR*






m907/a907 97.6% identity in 207 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2735>:










g908.seq




1
ATGAG.AAAA GCCGTCTAAG CCGGTATAAA CAAAATAAAC TCATTGGGCT


 


51
ATTTGTCGCA GGTGTAACTG CAAGAACAGC GGCAGAGTTG GTAGGCATTA


 


101
ATAAAAATAC CGCAGCCTAT GATTTTCATC GTTTACGATG ACTGATTTAT


 


151
CAAAACGGTC CGCATTTAGA AATGTTTGAT GGCGAAGTAG AAGCAGATGA


 


201
AAGTTATTTT GGCGGACAAC GCAAAGGCAA ACGCGGTCGC GGTGCTGCCG


 


251
GTAAAGTCGC CGTATTCGGT CTTTTGAAGC GAAATGGTAA GGTTTATACG


 


301
GTTACAGTAC CGAATACTCA AACCGCTACT TTATTTCCTA TTATCCGTGA


 


351
acaagtgaaa cctgacagta ttgtttatac ggattgttat CgTAGCTATG


 


401
ATGTATTAGA Tgtgagcgaa tttagccatT TTagcttcgc tgaaacttcg


 


451
ttttcgtaTC AATCACAGCA CACATTTTGC CGAACGACAA AACCATATTA


 


501
A






This corresponds to the amino acid sequence <SEQ ID 2736; ORF 908.ng>:










g908.pep




1
MXKSRLSRYK QNKLIGLFVA GVTARTAAEL VGINKNTAAY DFHRLR*LIY


 


51
QNGPHLEMFD GEVEADESYF GGQRKGKRGR GAAGKVAVFG LLKRNGKVYT


 


101
VTVPNTQTAT LFPIIREQVK PDSIVYTDCY RSYDVLDVSE FSHFSFAETS


 


151
FSYQSQHTFC RTTKPY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2737>:










m908.seq




1
ATGAGAAAAA GTCGTCTAAG CCAGTATAAA CAAAmTAAAC TCATTGAACT


 


51
GTTTGTCACA GGTGTAACTG CAAGAACGGC AGCAGAGTTA GTAGGCGTTA


 


101
ATAAAAATAC CGCAGCCTAT TATTTTCATC GTTTACGATT ACTTATTTAT


 


151
CAAAACAGTC CGCATTTGGA AATGTTTGAT GGCGAAGTAG AAGCAGATGA


 


201
AAGTTATTTT GGCGGACAAC GCAAAGGCAA ACGCGGTCGC GGTGCTGCCG


 


251
GTAAAGTCGC CGTATTCGGT CTTTTGAAGC GAAATGGTAA GGTTTATACG


 


301
GTTACAGTAC CGAATACTCA AACCGCTACT TTATTTCCTA TTATCCGTGA


 


351
ACAAGTGAAA CCTGACAGCA TTTTTTATAC GGATTGTTAT CGTAGCTATG


 


401
ATGTATTAGA TGTGCGCGAA TTTAGCCATT TTAGCTTCGC TGAAACTTCG


 


451
TTTTCGTATC AATCACAGCA CACATTTTGC CGAACGACAA AACCATATTA


 


501
A






This corresponds to the amino acid sequence <SEQ ID 2738; ORF 908>:










m908.pep




1
MRKSRLSQYK QXKLIELFVT GVTARTAAEL VGVNKNTAAY YFHRLRLLIY


 


51
QNSPHLEMFD GEVEADESYF GGQRKGKRGR GAAGKVAVFG LLKRNGKVYT


 


101
VTVPNTQTAT LFPIIREQVK PDSIFYTDCY RSYDVLDVRE FSHFSFAETS


 


151
FSYQSQHTFC RTTKPY*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 908 shows 93.4% identity over a 166 aa overlap with a predicted ORF (ORF 908.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2739>:










a908.seq




1
ATGAGAAAAA GTCGTCTAAG CCAGTATAAA CAAAATAAAC TCATTGAGCT


 


51
ATTTGTCGCA GGTGTAACTG CAAGAACGGC AGCAGAGTTA GTAGGCGTTA


 


101
ATAAAAATAC CGCAGCCTAT TATTTTCATC GTTTACGATT ACTTATTTAT


 


151
CAAAACAGTC CGCATTTGGA AATGTTTGAT GGCGAAGTAG AAGCAGATGA


 


201
AAGTTATTTT GGCGGACAAC GCAAAGGCAA ACGCGGTCGC GGTGCTGCCG


 


251
GTAAAGTCGC CGTATTCGGT CTTTTGAAGC GAAATGGTAA GGTTTATACG


 


301
GTTACAGTAC CGAATACTCA AACCGCTACT TTATTTCCTA TTATCCGTGA


 


351
ACAAGTGAAA CCTGACAGCA TTGTTTATAC GGATTGTTAT CGTAGCTATG


 


401
ATGTATTAGA TGTGCGCGAA TTTAGCCATT TTAGCTTCGC TGAAACTTCG


 


451
TTTTCGTATC AATCACAGCA CACATTTTGC CGAACGACAA AACCATATTA


 


501
A






This corresponds to the amino acid sequence <SEQ ID 2740; ORF 908.a>:










a908.pep




1
MRKSRLSQYK QNKLIELFVA GVTARTAAEL VGVNKNTAAY YFHRLRLLIY


 


51
QNSPHLEMFD GEVEADESYF GGQRKGKRGR GAAGKVAVFG LLKRNGKVYT


 


101
VTVPNTQTAT LFPIIREQVK PDSIVYTDCY RSYDVLDVRE FSHFSFAETS


 


151
FSYQSQHTFC RTTKPY*






m908/a908 98.2% identity in 166 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2741>:









g909.seq (partial)










1
atgcgtaaaa ccgtacttat cCTgaccatc tccgccgccc ttttgtcggg



 


51
ctgcacatgG gaaacttatc aagacggcag cggcaaaacc gccgtccgtg


 


101
caaaatgttc caccggcacg ccgctgtgtt ggcaagacgg gcgcggctcg


 


151
aaaaaggtgg actgcgacga gtacggtggc gaacgccggg ccgtgttgcg


 


201
caaccaaaag cgggggaagc ccgcgacgag gagagccgca acgctgggga


 


251
aaccgagttt ccgggcgagg gacggggggg ggcgggtgaa cagggcagaa


 


301
acgggggagg ggaagcgatc ggcgagg..






This corresponds to the amino acid sequence <SEQ ID 2742; ORF 909.ng>:









g909.pep (partial)










1
MRKTVLILTI SAALLSGCTW ETYQDGSGKT AVRAKCSTGT PLCWQDGRGS



 


51
KKVDCDEYGG ERRAVLRNQK RGKPATRRAA TLGKPSFRAR DGGGRVNRAE


 


101
TGEGKRSAR..






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2743>:










m909.seq




1
ATGCGTAAAA CCTTCCTCTT CCTGACCGCT GCCGCCGCCC TTTTGTCGGG


 


51
CTGCGCGTGG GAAACTTATC AAGACGGCAA CGGCAAGACC GCCGTCCGTC


 


101
AAAAATATCC CGCCGGCACG CCCGTTTATT ACCAAGACGG CAGCTACTCG


 


151
AAAAATATGA ACTACAACCA ATACCGTCCC GAACGCCATG CCGTGTTACC


 


201
CAATCAAACC GGCAACAACG CCGACGAAGA GCATCGCCAA CACTGGCAAA


 


251
AACCAAAGTT TCAAAACCGA TAA






This corresponds to the amino acid sequence <SEQ ID 2744; ORF 909>:










m909.pep




1
MRKTFLFLTA AAALLSGCAW ETYQDGNGKT AVRQKYPAGT PVYYQDGSYS


 


51
KNMNYNQYRP ERHAVLPNQT GNNADEEHRQ HWQKPKFQNR *






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 909 shows 53.3% identity over a 90 aa overlap with a predicted ORF (ORF 909.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2745>:










a909.seq




1
ATGCGTAAAA CCTTCCTTAT CCTGATGACT GCCGCCGCCC TTTTGTCGGG


 


51
CTGCGCGTGG GAAACTTATC AAGACGGCAA CGGCAAGACC GCCGTCCGTC


 


101
AAAAATATCC CGCCGGCACG CCCGTTTATT ACCAAGACGG CAGCTACTCG


 


151
AAAAATATGA ACTACAACCA ATACCGTCCC GAACGCCATG CCGTGTTACC


 


201
CAACCAAACC GGCAACAACG CCGACGAAGA GCATCGCCAA CACTGGCAAA


 


251
AGCCCAAATT TCAAAACCGA TAA






This corresponds to the amino acid sequence <SEQ ID 2746; ORF 909.a>:










a909.pep




1
MRKTFLILMT AAALLSGCAW ETYQDGNGKT AVRQKYPAGT PVYYQDGSYS


 


51
KNMNYNQYRP ERHAVLPNQT GNNADEEHRQ HWQKPKFQNR *






m909/a909 96.7% identity in 90 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2747>:










g910.seq




1
ATGAAAAAAC TGTTATTGGC CGCCGTTGTT TCCCTAAATG CCGCAACCGC


 


51
ATTTGCCGGC GACTCTGCCG AGCGTCAGAT TTACGGCGAT CCCCATTTTG


 


101
AACAAAACCG CACAAAAGCC GTGAAAATGT TGGAACAGCG CGGTTATCAG


 


151
GTTTACGATG TCGATGCCGA CGACTACTGG GGCAAACCTG TTTTGGAAGT


 


201
GGAAGCCTAT AAAGACGGCC GCGAATACGA CATCGTGTTG TCTTACCCCG


 


251
ACCTGAAAAT CATCAAAGAG CAGCTCGATC GCTGA






This corresponds to the amino acid sequence <SEQ ID 2748; ORF 910.ng>:










g910.pep




1
MKKLLLAAVV SLNAATAFAG DSAERQIYGD PHFEQNRTKA VKMLEQRGYQ


 


51
VYDVDADDYW GKPVLEVEAY KDGREYDIVL SYPDLKIIKE QLDR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2749>:










m910.seq




1
ATGAAAAAAC TGTTATTGGC TGCCGTTGTT TCTCTGAGTG CCGCTGCCGC


 


51
ATTTGCCGGC GACTCTGCCG AGCGTCAGAT TTACGGCGAT CCCCATTTTG


 


101
AACAAAACCG CACAAAAGCT GTGAAAATGT TGGAGCAGCG CGGTTATCAG


 


151
GTTTACGATG TCGATGCCGA CGACCATTGG GGTAAGCCTG TGCTGGAAGT


 


201
GGAAGCCTAT AAAGACGGCC GCGAATACGA CATCGTGTTG TCTTACCCCG


 


251
ACCTGAAAAT CATCAAAGAG CAGCTCGATC GCTGA






This corresponds to the amino acid sequence <SEQ ID 2750; ORF 910>:










m910.pep




1
MKKLLLAAVV SLSAAAAFAG DSAERQIYGD PHFEQNRTKA VKMLEQRGYQ


 


51
VYDVDADDHW GKPVLEVEAY KDGREYDIVL SYPDLKIIKE QLDR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 910 shows 96.8% identity over a 94 aa overlap with a predicted ORF (ORF 910.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2751>:










a910.seq




1
ATGAAAAAAC TGTTATTGGT CGCCGTTGTT TCCTTGAGTG CCGCAACCGC


 


51
ATTTGCCGGC GACTCTGCCG AGCGTCAGAT TTACGGCGAT CCCTATTTTG


 


101
AACAAAACCG CACAAAAGCC GTGAAAATGT TGGAACAGCG CGGTTATCAG


 


151
GTTCACGATG TCGATGCCGA CGACCATTGG GGCAAACCTG TTTTGGAAGT


 


201
GGAAGCCTAT AAAGACGGCC GCGAATACGA CATTGTGTTG TCTTACCCCG


 


251
ACCTGAAAAT CATCAAAGAG CAGCTCGATC GCTGA






This corresponds to the amino acid sequence <SEQ ID 2752; ORF 910.a>:










a910.pep




1
MKKLLLVAVV SLSAATAFAG DSAERQIYGD PYFEQNRTKA VKMLEQRGYQ


 


51
VHDVDADDHW GKPVLEVEAY KDGREYDIVL SYPDLKIIKE QLDR*






m910/a910 95.7% identity in 94 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2753>:










g911.seq




1
ATGAAAAAGA ACATATTGGA ATTTTGGGTC GGACTGTTCG TCTTGATCGG


 


51
CGCGGCGGCG GTTGCCTTTC TCGCTTTCCG CGTGGCGGGC GGCGCGGCGT


 


101
TCGGCGGTTC GGACAAAACT TACGCCGTTT ATGCCGATTT CGGCGACATC


 


151
GGCGGTTTGA AGGTCAATGC CCCCGTCAAA TCCGCAGGCG TATTGGTCGG


 


201
GCGCGTCGGC GCTATCGGGC TTGACCCGAA ATCCTATCAG GCGAGGGTGC


 


251
GCCTTGATTT GGACGGCAAG TATCAGTTCA GCAGTGACGT TTCCGCGCAA


 


301
ATCCTGACTT CGGGACTTTT GGGCGAACAG TACATCGGGC TGCAGCAGGG


 


351
CGGCGATACG GAAAACCTTG CTGCCGGCGA CACCATCTCC GTAACCAGTT


 


401
CTGCAATGGT TCTGGAAAAC CTGATCGGTA AATTCATGAC CAGCTTCGCC


 


451
GAGAAAAACG CTGAGGGCGG CAATGCGGAA AAAGCCGcag aAtaa






This corresponds to the amino acid sequence <SEQ ID 2754; ORF 911.ng>:










g911.pep




1
MKKNILEFWV GLFVLIGAAA VAFLAFRVAG GAAFGGSDKT YAVYADFGDI


 


51
GGLKVNAPVK SAGVLVGRVG AIGLDPKSYQ ARVRLDLDGK YQFSSDVSAQ


 


101
ILTSGLLGEQ YIGLQQGGDT ENLAAGDTIS VTSSAMVLEN LIGKFMTSFA


 


151
EKNAEGGNAE KAAE*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2755>:










m911.seq




1
ATGAAGAAGA ACATATTGGA ATTTTGGGTC GGACTGTTCG TCCTGATTGG


 


51
CGCGGCGGCG GTTGCCTTTC TCGCTTTCCG CGTGGCCGGC GGTGCGGCGT


 


101
TCGGCGGTTC GGACAAAACT TACGCCGTTT ATGCCGATTT CGGCGACATC


 


151
GGCGGTTTGA AGGTCAATGC CCCCGTCAAA TCCGCAGGCG TATTGGTCGG


 


201
GCGCGTCGGC GCTATCGGAC TTGACCCGAA ATCCTATCAG GCGAGGGTGC


 


251
GCCTCGATTT GGACGGCAAG TATCAGTTCA GCAGCGACGT TTCCGCGCAA


 


301
ATCCTGACTT CGGGACTTTT GGGCGAGCAG TACATCGGGC TGCAGCAGGG


 


351
CGGCGACACG GAAAACCTTG CTGCCGGCGA CACCATCTCC GTAACCAGTT


 


401
CTGCAATGGT TCTGGAAAAC CTTATCGGCA AATTCATGAC GAGTTTTGCC


 


451
GAGAAAAATG CCGACGGCGG CAATGCGGAA AAAGCCGCCG AATAA






This corresponds to the amino acid sequence <SEQ ID 2756; ORF 911>:










m911.pep




1
MKKNILEFWV GLFVLIGAAA VAFLAFRVAG GAAFGGSDKT YAVYADFGDI


 


51
GGLKVNAPVK SAGVLVGRVG AIGLDPKSYQ ARVRLDLDGK YQFSSDVSAQ


 


101
ILTSGLLGEQ YIGLQQGGDT ENLAAGDTIS VTSSAMVLEN LIGKFMTSFA


 


151
EKNADGGNAE KAAE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 911 shows 99.4% identity over a 164 aa overlap with a predicted ORF (ORF 911.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2757>:










a911.seq




1
ATGAAAAAGA ACATATTGGA ATTTTGGGTC GGACTGTTCG TCCTGATTGG


 


51
CGCGGCGGCG GTTGCCTTTC TCGCTTTCCG CGTGGCCGGC GGTGCGGCGT


 


101
TCGGCGGTTC GGACAAAACT TACGCCGTTT ATGCCGATTT CGGCGACATC


 


151
GGCGGTTTGA AGGTCAATGC CCCCGTCAAA TCCGCAGGCG TATTGGTCGG


 


201
GCGCGTCGGC GCTATCGGAC TTGACCCGAA ATCCTATCAG GCGAGGGTGC


 


251
GCCTCGATTT GGACGGCAAG TATCAGTTCA GCAGCGACGT TTCCGCGCAA


 


301
ATCCTGACTT CGGGACTTTT GGGCGAGCAG TACATCGGGC TGCAGCAGGG


 


351
CGGCGACACG GAAAACCTTG CTGCCGGCGA CACCATCTCC GTAACCAGTT


 


401
CTGCAATGGT TCTGGAAAAC CTTATCGGCA AATTCATGAC GAGTTTTGCC


 


451
GAGAAAAATG CCGACGGCGG CAATGCGGAA AAAGCCGCCG AATAA






This corresponds to the amino acid sequence <SEQ ID 2758; ORF 911.a>:










a911.pep




1
MKKNILEFWV GLFVLIGAAA VAFLAFRVAG GAAFGGSDKT YAVYADFGDI


 


51
GGLKVNAPVK SAGVLVGRVG AIGLDPKSYQ ARVRLDLDGK YQFSSDVSAQ


 


101
ILTSGLLGEQ YIGLQQGGDT ENLAAGDTIS VTSSAMVLEN LIGKFMTSFA


 


151
EKNADGGNAE KAAE*






m911/a911 100.0% identity in 164 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2759>:










g912.seq




1
gtgAAAAaat cctcctTcat cagcGCATTG GGCATCGgtA TTTTGAGCAT


 


51
CGGCATGGCA TTTGCCTCCC CGGCCGACGC AGTGGGACAA ATCCGCCAAA


 


101
ACGCCACACA GGTTTTGACC ATCCTCAAAA GCGGCGACGC GGCTTCTGCA


 


151
CGCCCAAAAG CCGAAGCCTA TGCGGTTCCC TATTTCGATT TCCAACGTAT


 


201
GACCGCATTG GCGGTCGGCA ACCCTTGGCG TACCGCGTCC GACGCGCAAA


 


251
AACAAGCGTT GGCCAAAGAA TTTCAAACCC TGCTGATCCG CACCTATTCC


 


301
GGCACGATGC TGAAATTCAA AAACGCGACC GTCAACGTCA AAGACAATCC


 


351
CATCGTCAAT AAGGGCGGCA AGGAAATCGT CGTCCGTGCC GAAGTCGGCA


 


401
TCCCCGGTCA GAAGCCCGTC AATATGGACT TTACCACCTA CCAAAGCGGC


 


451
GGCAAATACC GTACCTACAA CGTCGCCATC GAAGGCACGA GCCTGGTTAC


 


501
CGTGTACCGC AACCAATTCG GCGAAATCAT CAAAGCCAAA GGCATCGACG


 


551
GGCTGATTGC CGAGTTGAAA GCCAAAAACG GCGGCAAATA A






This corresponds to the amino acid sequence <SEQ ID 2760; ORF 912.ng>:










g912.pep




1
VKKSSFISAL GIGILSIGMA FASPADAVGQ IRQNATQVLT ILKSGDAASA


 


51
RPKAEAYAVP YFDFQRMTAL AVGNPWRTAS DAQKQALAKE FQTLLIRTYS


 


101
GTMLKFKNAT VNVKDNPIVN KGGKEIVVRA EVGIPGQKPV NMDFTTYQSG


 


151
GKYRTYNVAI EGTSLVTVYR NQFGEIIKAK GIDGLIAELK AKNGGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2761>:










m912.seq




1
ATGAAAAAAT CCTCCCTCAT CAGCGCATTG GGCATCGGTA TTTTGAGCAT


 


51
CGGCATGGCA TTTGCCGCCC CTGCCGACGC GGTAAGCCAA ATCCGTCAAA


 


101
ACGCCACTCA AGTATTGAGC ATCTTAAAAA ACGGCGATGC CAACACCGCT


 


151
CGCCAAAAAG CCGAAGCCTA TGCGATTCCC TATTTCGATT TCCAACGTAT


 


201
GACCGCATTG GCGGTCGGCA ACCCTTGGCG CACCGCGTCC GACGCGCAAA


 


251
AACAAGCGTT GGCCAAAGAA TTTCAAACCC TGCTGATCCG CACCTATTCC


 


301
GGCACGATGC TGAAATTAAA AAACGCCAAC GTCAACGTCA AAGACAATCC


 


351
CATCGTCAAT AAAGGCGGCA AAGAAATCAT CGTCCGCGCC GAAGTCGGCG


 


401
TACCCGGGCA AAAACCCGTC AACATGGACT TCACCACCTA CCAAAGCGGC


 


451
GGTAAATACC GTACCTACAA CGTCGCCATC GAAGGCGCGA GCCTGGTTAC


 


501
CGTGTACCGC AACCAATTCG GCGAAATTAT CAAAGCGAAA GGCGTGGACG


 


551
GACTGATTGC CGAGTTGAAA GCCAAAAACG GCGGCAAATA A






This corresponds to the amino acid sequence <SEQ ID 2762; ORF 912>:










m912.pep




1
MKKSSLISAL GIGILSIGMA FAAPADAVSQ IRQNATQVLS ILKNGDANTA


 


51
RQKAEAYAIP YFDFQRMTAL AVGNPWRTAS DAQKQALAKE FQTLLIRTYS


 


101
GTMLKLKNAN VNVKDNPIVN KGGKEIIVRA EVGVPGQKPV NMDFTTYQSG


 


151
GKYRTYNVAI EGASLVTVYR NQFGEIIKAK GVDGLIAELK AKNGGK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 912 shows 91.8% identity over a 196 aa overlap with a predicted ORF (ORF 912.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2763>:










a912.seq




1
ATGAAAAAAT CCTCCTTCAT CAGCGCATTG GGCATCGGTA TTTTGAGCAT


 


51
CGGCATGGCA TTTGCCGCCC CTGCCGACGC GGTAAACCAA ATCCGTCAAA


 


101
ACGCCACTCA AGTATTGAGC ATCTTAAAAA GCGGTGATGC CAACACCGCC


 


151
CGCCAAAAAG CCGAAGCCTA TGCGATTCCC TATTTCGATT TCCAACGTAT


 


201
GACCGCATTG GCGGTCGGCA ACCCTTGGCG CACCGCGTCC GACGCGCAAA


 


251
AACAAGCGTT GGCCAAAGAA TTTCAAACCC TGCTGATCCG CACCTATTCC


 


301
GGCACGATGC TGAAATTAAA AAACGCCAAC GTCAACGTCA AAGACAATCC


 


351
CATCGTCAAT AAAGGCGGCA AAGAAATCAT CGTCCGCGCC GAAGTCGGCG


 


401
TACCCGGGCA AAAACCCGTC AACATGGACT TCACCACCTA CCAAAGCGGC


 


451
GGTAAATACC GTACCTACAA CGTCGCCATC GAAGGCGCGA GCCTGGTTAC


 


501
CGTGTACCGC AACCAATTCG GCGAAATTAT CAAAGCGAAA GGCGTGGACG


 


551
GACTGATTGC CGAGTTGAAG GCTAAAAACG GCAGCAAGTA A






This corresponds to the amino acid sequence <SEQ ID 2764; ORF 912.a>:










a912.pep




1
MKKSSFISAL GIGILSIGMA FAAPADAVNQ IRQNATQVLS ILKSGDANTA


 


51
RQKAEAYAIP YFDFQRMTAL AVGNPWRTAS DAQKQALAKE FQTLLIRTYS


 


101
GTMLKLKNAN VNVKDNPIVN KGGKEIIVRA EVGVPGQKPV NMDFTTYQSG


 


151
GKYRTYNVAI EGASLVTVYR NQFGEIIKAK GVDGLIAELK AKNGSK*






m912/a912 98.0% identity in 196 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2765>:










g913.seq




1
atGAAAAAAA CCGCCTACGC CATCCTCCTG CTGATCGGGT TCGCTTCCGC


 


51
CCCTGCATTT GCAGAAACCC GCCCCGCCGA CCCTTATGAA GGCTACAACC


 


101
GCGCCGTTTC CAAATTCAAC GACCAAGCCG ACCGCTACAT TTTCGCCCCT


 


151
GCCGCGCGCG GCTACCGCAA AGTTACGCCG AAACCCGTCC GCGCCGGCGT


 


201
GTCCAATTTT TTTAACAACC TGCGCGACGT GGTCAGTTTC GGCAGCAATA


 


251
TCTTGCGTTT GGAcatCAAA cgcgcAAGcg aAGACCtcgT CCGcgtcggc


 


301
atCAATACCA CCTTCGGTTT GGgcgGGCTC ATTGATATTG CCGGcgcGGg


 


351
cggcgttccc gacaataaaa AcacTttgGg cgacacgttt gcctcgtGGG


 


401
GctgGAAAaa cagcaATTAT TTCGTgttgc CCGtcttagg cccgtccacc


 


451
gtccgcgacg cgctcggcac gggcattacc tCTGTTTATC CGCccaagaa


 


501
tatcgttttc catacccctg ccggacgctg GGgcacgact gCCGCTGCCG


 


551
CCGTcagtac gcgcgaaggc ctcctcgatt tgaccgacag TCtggacgaa


 


601
gccgccatCG ACAAATACAG CTACACGCGc gacctctata tgAAAGTCCG


 


651
CGcacgGCag AccgGTGCAA CACCTGCCGA AGgtacggaa gataacatcg


 


701
acatcgacat cgACGAATTG GTCGAAAGTG CCGAAACCGG CGCGGCAGAG


 


751
CCCGCCGTTC ACGAAGATTC CGTATCCGAA ACACAGGCAG AAGCAGCAGG


 


801
GGAAGCCGAA ACGCAACCTG GAACACAACC CTAA






This corresponds to the amino acid sequence <SEQ ID 2766; ORF 913.ng>:










g913.pep




1
MKKTAYAILL LIGFASAPAF AETRPADPYE GYNRAVSKFN DQADRYIFAP


 


51
AARGYRKVTP KPVRAGVSNF FNNLRDVVSF GSNILRLDIK RASEDLVRVG


 


101
INTTFGLGGL IDIAGAGGVP DNKNTLGDTF ASWGWKNSNY FVLPVLGPST


 


151
VRDALGTGIT SVYPPKNIVF HTPAGRWGTT AAAAVSTREG LLDLTDSLDE


 


201
AAIDKYSYTR DLYMKVRARQ TGATPAEGTE DNIDIDIDEL VESAETGAAE


 


251
PAVHEDSVSE TQAEAAGEAE TQPGTQP*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2767>:










m913.seq




1
ATGAAAAAAA CCGCCTATGC CTTCCTCCTG CTGATCGGGT TCGCTTCCGC


 


51
CCCTGCATTT GCCGAAACCC GCCCCGCCGA CCCTTATGAA GGCTACAACC


 


101
GCGCCGTTTT CAAATTCAAC GACCAAGCCG ACCGCTACAT TTTCGCCCCT


 


151
GCCGCGCGCG GCTACCGCAA AGTTGCGCCG AAACCCGTCC GCGCCGGCGT


 


201
GTCCAATTTT TTTAACAACC TGTGCGACGT GGTCAGCTTC GGCAGCAATA


 


251
TCTTGCGCTT GGACATCAAA CGCGCAAGCG AAGACCTTGT CCGCGTCGGC


 


301
ATCAACACCA CTTTCGGTTT GGGCGGGCTT ATCGACATCG CCGGCGCGGG


 


351
CGGCATTCCC GACAATAAAA ACACCTTGGG CGACACGTTT GCCTCGTGGG


 


401
GATGGAAAAA CAGCAATTAT TTCGTGTTGC CCGTCTTAGG GCCGTCCACC


 


451
GTCCGCGACG CGCTCGGCAC GGGTATTACC TCCGTTTATT CGCCCAAGAA


 


501
TATCGTCTTC CGCACCCCTG TCGGACGCTG GGGCACGACT GCCGTATCCG


 


551
CCGTCAGTAC GCGCGAAGGC CTgCTCGATT TGACCGACAG TCTGGACGAA


 


601
GCCGCCATCG ACAAATACAG CTACACGCGC GACCTCTATA TGAAAGTCCG


 


651
TGCGCGGCAG ACCGGTGCAA CACCTGCCGA AGgTACGGAA GATAACATCG


 


701
ACATCGACGA ATTGGTCGAA AGTGCCGAAA CCGGCGCGGC GGAAACTGCC


 


751
GTTCAAGAAG ATTCCGTATC CGAAACACAG GCAGAAGCAG CAGGGGAAGC


 


801
CGAAACGCAA CCTGGAACAC AACCTTAA






This corresponds to the amino acid sequence <SEQ ID 2768; ORF 913>:










m913.pep




1
MKKTAYAFLL LIGFASAPAF AETRPADPYE GYNRAVFKFN DQADRYIFAP


 


51
AARGYRKVAP KPVRAGVSNF FNNLCDVVSF GSNILRLDIK RASEDLVRVG


 


101
INTTFGLGGL IDIAGAGGIP DNKNTLGDTF ASWGWKNSNY FVLPVLGPST


 


151
VRDALGTGIT SVYSPKNIVF RTPVGRWGTT AVSAVSTREG LLDLTDSLDE


 


201
AAIDKYSYTR DLYMKVRARQ TGATPAEGTE DNIDIDELVE SAETGAAETA


 


251
VQEDSVSETQ AEAAGEAETQ PGTQP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 913 shows 94.9% identity over a 277 aa overlap with a predicted ORF (ORF 913.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2769>:










a913.seq




1
ATGAAAAAAA CCGCCTATGC CTTCCTCCTG CTGATCGGGT TCGCTTCCGC


 


51
CCCTGCATTT GCCGAAACCC GCCCCGCCGA CCCTTATGAA GGCTACAACC


 


101
GCGCCGTTTT CAAATTCAAC GACCAAGCCG ACCGCTACAT TTTCGCCCCT


 


151
GCCGCGCGCG GCTACCGCAA AGTTGCGCCG AAACCCGTCC GCGCCGGCGT


 


201
GTCCAATTTT TTTAACAACC TGTGCGACGT GGTCAGCTTC GGCAGCAATA


 


251
TCTTGCGCTT AGACATCAAA CGCGCAAGCG AAGACCTTGT CCGCGTCGGT


 


301
ATCAACACCA CTTTCGGTTT GGGCGGGCTT ATCGACATCG CCGGCGCGGG


 


351
CGGCATTCCC GACAATAAAA ACACCTTGGG CGACACGTTT GCTTCGTGGG


 


401
GATGGAAAAA CAGCAATTAT TTCGTGTTGC CCGTCTTAGG GCCGTCCACC


 


451
GTCCGCGACG CGCTCGGCAC GGGTATTACC TCCGTTTATT CGCCCAAGAA


 


501
TATCGTCTTC CGCACCCCTG TCGGACGCTG GGGCACGACT GCCGTATCCG


 


551
CCGTCAGTAC GCGCGAAGGC CTGCTCGATT TGACCGACAG TCTGGACGAA


 


601
GCCGCCATCG ACAAATACAG CTACACGCGC GACCTCTATA TGAAAGTCCG


 


651
TGCGCGGCAG ACCGGTGCAA CACCTGCCGA AGGTACGGAA GATAACATCG


 


701
ACATCGACGA ATTGGTCGAA AGTGCCGAAA CCGGCGCGGC GGAAACTGCC


 


751
GTTCAAGAAG ATTCCGTATC CGAAACACAG GCAGAAGCAG CAGGGGAAGC


 


801
CGAAACGCAA CCTGGAACAC AACCTGGAAC ACAACCTTAA






This corresponds to the amino acid sequence <SEQ ID 2770; ORF 913.a>:










a913.pep




1
MKKTAYAFLL LIGFASAPAF AETRPADPYE GYNRAVFKFN DQADRYIFAP


 


51
AARGYRKVAP KPVRAGVSNF FNNLCDVVSF GSNILRLDIK RASEDLVRVG


 


101
INTTFGLGGL IDIAGAGGIP DNKNTLGDTF ASWGWKNSNY FVLPVLGPST


 


151
VRDALGTGIT SVYSPKNIVF RTPVGRWGTT AVSAVSTREG LLDLTDSLDE


 


201
AAIDKYSYTR DLYMKVRARQ TGATPAEGTE DNIDIDELVE SAETGAAETA


 


251
VQEDSVSETQ AEAAGEAETQ PGTQPGTQP*






m913/a913 100.0% identity in 275 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2771>:










g914.seq




1
ATGAAAAAAT GTATTTTGGG CATTTTGACC GCGTGTGCCG CCATGCCTGC


 


51
ATTTGCCGAC AGAATCAGCG ATTTGGAAGC ACGTCTGGCG CAGTTGGAAC


 


101
ACCGTGTCGC CGTATTGGAA AGCGGCGGCA ATACCGTCAA AATCGACCTT


 


151
TTCGGTTCAA ATTCCACCAT GTATGTATGC AGCGTTACGC CTTTTCAGAA


 


201
GacgtttGag gCAAGCGATC GGAATGAAGG CGTGGCGCGG CAGAAAGTGC


 


251
GTCAGGCGTG CAACCGCGAA ACTTCGGCAA TGTTTTGCGG AGATGAGGCA


 


301
ATCCGATGCA GAAAATTCGA TTGATGTATC GGTTGGACGG ATAAAGAAAC


 


351
GGATACGGAG CTTGGCTTCC GTCTCTGTTT TTCTCTGCCC GATTTTCCAT


 


401
GCATCGGGTT TCAGACGGCA TTGGAGTGTC AGTCGTGTTC TGCCGATTCG


 


451
taggctTCGA CGATTTTTTG CACCAGAGGA TGCCGGACAA CGTCTTCGCC


 


501
GGTGAAGGTA TGGAAATACA GTCCTGCCAC GCCGTGCAGT TTCTCACGTG


 


551
CGTCTTTCAA TCCCGATTTG ATGTTTTTGG GCAGGTcgaT TTGGCTGGTG


 


601
TCGCCGGTAA TGACGGCTTT CGCgccgaag ccGATGCGGG TCAGGAACAT


 


651
TTTCATTTGT TCGGGCGTGg tgTtttGcgC TTCGTCGAGG ATGATGTATG


 


701
CGCCGTTGAg cgTCCTGCCG CGCATATAG






This corresponds to the amino acid sequence <SEQ ID 2772; ORF 914.ng>:










g914.pep




1
MKKCILGILT ACAAMPAFAD RISDLEARLA QLEHRVAVLE SGGNTVKIDL


 


51
FGSNSTMYVC SVTPFQKTFE ASDRNEGVAR QKVRQACNRE TSAMFCGDEA


 


101
IRCRKFD*CI GWTDKETDTE LGFRLCFSLP DFPCIGFQTA LECQSCSADS


 


151
*ASTIFCTRG CRTTSSPVKV WKYSPATPCS FSRASFNPDL MFLGRSIWLV


 


201
SPVMTAFAPK PMRVRNIFIC SGVVFCASSR MMYAPLSVLP RI*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2773>:










m914.seq




1
ATGAAAAAAT GTATTTTGGG CATTTTGACC GCGTGTGCCG CCATGCCTGC


 


51
ATTTGCCGAC AGAATCGGCG ATTTGGAAGC ACGTCTGGCG CAGTTGGAAC


 


101
ACCGTGTCGC CGTATTGGAA AGCGGCGGCA ATACCGTCAA AATCGACCTT


 


151
TTCGGTTCAA ATTCCACCAT GTATGTATGC AGCGTTACGC CTTTTCAGAA


 


201
GACGTTTGAG GCAAGCGATC GGAATGAAGG CGTGGCGCGG CAGAAAGTGC


 


251
GTCAGGCGTG CAACCGCGAA ACTTCGGCAA TGTTTTGCGA AGATGAGGCA


 


301
ATCCGATGCA GAAAATTCGA TTGATGTATC GGTTGGACGG ATAAAGAAAC


 


351
GGATACGGAT ACGGAGCTTG GCTTCCGTAT CTGTTTTTCT CTGCCTGATT


 


401
TTCCATGCAT CGGGTTTCAG ACGGCATTGG AATGTCAGTC GTGTTCTGCC


 


451
GATTCGTAGG CTTCGACGAT TTTTTGCACC AAAGGATGCC GGACAACGTC


 


501
TTCGCCGGTA AAGGTGTGGA AATACAGCCC TTCCACGTTG TGCAGTTTCT


 


551
CACGCGCATC TTTTAATCCC GATTTGATGT TTTTGGGCAG GTCGATTTGG


 


601
CTGGTGTCGC CGGTAATGAC GGCTTTCGCG CCGAAGCCGA TGCGGGTCAG


 


651
GAACATTTTC ATTTGTTCGG GCGTGGTGTT TTGCGCTTCG TCGAGGATGA


 


701
TGTATGCGCC GTTGAGCGTC CTGCCGCGCA TATAG






This corresponds to the amino acid sequence <SEQ ID 2774; ORF 914>:










m914.pep




1
MKKCILGILT ACAAMPAFAD RIGDLEARLA QLEHRVAVLE SGGNTVKIDL


 


51
FGSNSTMYVC SVTPFQKTFE ASDRNEGVAR QKVRQACNRE TSAMFCEDEA


 


101
IRCRKFDXCI GWTDKETDTD TELGFRICFS LPDFPCIGFQ TALECQSCSA


 


151
DSXASTIFCT KGCRTTSSPV KVWKYSPSTL CSFSRASFNP DLMFLGRSIW


 


201
LVSPVMTAFA PKPMRVRNIF ICSGVVFCAS SRMMYAPLSV LPRI*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 914 shows 96.7% identity over a 244 aa overlap with a predicted ORF (ORF 914.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2775>:










a914.seq




1
ATGAAAAAAT GTATTTTGGG CATTTTGACC GCGTGTGCCG CCATGCCTGC


 


51
ATTTGCCGAC AGAATCGGCG ATTTGGAAGC ACGTCTGGCG CAGTTGGAAC


 


101
ACCGTGTCGC CGTATTGGAA AGCGGCAGCA ATACCGTCAA AATCGACCTT


 


151
TTCGGTTCAA ATTCCACCAT GTATGTATGC AGCGTTACGC CTTTTCAGAA


 


201
GACGTTTGAG GCAAGCGATC GGAATGAAGG CGTGGCGCGG CAGAAAGTGC


 


251
GTCAGGCGTG CAACCGCGAA ACTTCGGCAA TGTTTTGCGA AGATGAGGCA


 


301
ATCCGATGCA GAAAATTCGA TTGATGTATC GGTTGGACGG ATAAAGAAAC


 


351
GGATACGGAG CTTGGCTTCC GTATCTGTTT TTCTCTGCCC GATTTTCCAT


 


401
GCATCGGGTT TCAGACGGCA TTGGAATGTC AGTCGTGTTC TGCCGATTCG


 


451
TAGGCTTCGA CGATTTTTTG CACCAAAGGA TGCCGGACAA CGTCTTCGCC


 


501
GGTAAAGGTG TGGAAATACA GCCCTTCCAC GCCGTGCAGT TTCTCACGCG


 


551
CATCTTTTAA TCCCGATTTG ATGTTTTTGG GCAGGTCGAT TTGGCTGGTG


 


601
TCGCCGGTAA TGACGGCTTT CGCGCCGAAG CCGATGCGGG TCAGGAACAT


 


651
TTTCATTTGT TCGGGCGTGG TGTTTTGCGC TTCGTCGAGG ATGATGTATG


 


701
CGCCGTTGAG CGTCCTGCCG CGCATATAG






This corresponds to the amino acid sequence <SEQ ID 2776; ORF 914.a>:










a914.pep




1
MKKCILGILT ACAAMPAFAD RIGDLEARLA QLEHRVAVLE SGSNTVKIDL


 


51
FGSNSTMYVC SVTPFQKTFE ASDRNEGVAR QKVRQACNRE TSAMFCEDEA


 


101
IRCRKFD*CI GWTDKETDTE LGFRICFSLP DFPCIGFQTA LECQSCSADS


 


151
*ASTIFCTKG CRTTSSPVKV WKYSPSTPCS FSRASFNPDL MFLGRSIWLV


 


201
SPVMTAFAPK PMRVRNIFIC SGVVFCASSR MMYAPLSVLP RI*






m914/a914 98.4% identity in 244 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2777>:










g915.seq




1
ATGAAGAAAA CCCTGTTGGc AATTGTTGCC gtTTTCGCCT TAAGTGCCTG


 


51
CCGGCaggcg gaAGaggcac cgccgCCTTT ACCCCGGCAG AtTAGCGacc


 


101
gttcggtcgg aCACTAttgC Agtatgaacc tgaccgaaca caacggcccc


 


151
aaagcccaga tttttttgaa cGGCAAACCC GATCAGCCCG TTTGGTTCTC


 


201
CACCGTcaag cagatgttcg GCTATACCAA GCTGCCCGAA GAGCCCAAAG


 


251
GCATCCGCGT GATTTACGTT ACCGATATGG GCAATGTTAC CGATTGGACG


 


301
AATCCTAATG CCGACACGGA GTGGATAGAT GCGAAAAAAG CCTTTTACGT


 


351
CATCGACAGC GGCTTTATCG GCGGTATGGG CGCGGAAGAC GCGCTGCCGT


 


401
TCGGCAACAA GGAGCAGGCT GAAAAATTTG CAAAGGATAA AGGCGGCAAG


 


451
GTCGTCGGTT TTGACGATAT GCCCGATGCT TACATTTTCA AGTAA






This corresponds to the amino acid sequence <SEQ ID 2778; ORF 915.ng>:










g915.pep




1
MKKTLLAIVA VFALSACRQA EEAPPPLPRQ ISDRSVGHYC SMNLTEHNGP


 


51
KAQIFLNGKP DQPVWFSTVK QMFGYTKLPE EPKGIRVIYV TDMGNVTDWT


 


101
NPNADTEWID AKKAFYVIDS GFIGGMGAED ALPFGNKEQA EKFAKDKGGK


 


151
VVGFDDMPDA YIFK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2779>:










m915.seq




1
ATGAAAAAAA CCCTGTTGGC AATTGTTGCC GTTTCCGCCT TAAGTGC.tG


 


51
CCGGCAGGCG GAAGAGGGAC CGCCGCCTTT ACCcCGGCAG ATTAGCGACC


 


101
GTTCGGTCGG ACACTATTGC AGTATGAACC TGACCGAACA CAACGGCCCC


 


151
AAAGCCCAGA TTTTCTTGAA CGGCAAACCC GATCAGCCCG TtTGGTTCTC


 


201
CACCATCAAG CAGATGTTCG GCTATACCAA GCTGCCCGAA GAGCCTAAAG


 


251
GCATCCGCGT GATTTACGTT ACCGATATGG GCAATGTTAC CGATTGGACG


 


301
AATCCCAATG CCGACACGGA GTGGATGGAT GCGAAAAAAG CCTTTTACGT


 


351
CATCGACAGC GGCTTTATCG GCGGTATGGG TGCGGAAGAC GCGCTGCCGT


 


401
TCGGCAACAA AGAGCAGGCT GAGAAATTTG CAAAGGATAA AGGCGGTAAG


 


451
GTTGTCGGTT TCGACGATAT GCCTGATACC TATATTTTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 2780; ORF 915>:










m915.pep




1
MKKTLLAIVA VSALSXCRQA EEGPPPLPRQ ISDRSVGHYC SMNLTEHNGP


 


51
KAQIFLNGKP DQPVWFSTIK QMFGYTKLPE EPKGIRVIYV TDMGNVTDWT


 


101
NPNADTEWMD AKKAFYVIDS GFIGGMGAED ALPFGNKEQA EKFAKDKGGK


 


151
VVGFDDMPDT YIFK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 915 shows 97.0% identity over a 164 aa overlap with a predicted ORF (ORF 915.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2781>:










a915.seq




1
ATGAAAAAAA CCCTGTTGGC AATTGTTGCC GTTTCCGCCT TAAGTGCCTG


 


51
CCGGCAGGCG GAAGAGGGAC CGCCGCCTTT ACCCCGGCAG ATTAGCGACC


 


101
GTTCGGTCGG ACACTATTGC AGTATGAACC TGACCGAACA CAACGGCCCC


 


151
AAAGCCCAGA TTTTCTTGAA CGGCAAACCC GATCAGCCCG TTTGGTTCTC


 


201
CACCATCAAG CAGATGTTCG GCTATACCAA GCTGCCCGAA GAGCCTAAAG


 


251
GCATCCGCGT GATTTACGTT ACCGATATGG GCAATGTTAC CGATTGGACG


 


301
AATCCCAATG CCGACACGGA GTGGATGGAT GCGAAAAAAG CCTTTTACGT


 


351
CATCGACAGC GGCTTTATCG GCGGTATGGG TGCGGAAGAC GCGCTGCCGT


 


401
TCGGCAACAA AGAGCAGGCT GAGAAATTTG CAAAGGATAA AGGCGGTAAG


 


451
GTTGTCGGTT TCGACGATAT GCCTGATACC TATATTTTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 2782; ORF 915.a>:










a915.pep




1
MKKTLLAIVA VSALSACRQA EEGPPPLPRQ ISDRSVGHYC SMNLTEHNGP


 


51
KAQIFLNGKP DQPVWFSTIK QMFGYTKLPE EPKGIRVIYV TDMGNVTDWT


 


101
NPNADTEWMD AKKAFYVIDS GFIGGMGAED ALPFGNKEQA EKFAKDKGGK


 


151
VVGFDDMPDT YIFK*






m915/a915 99.4% identity in 164 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2783>:










g917.seq




1
ATGGTCAAac atctgccacT cgcCGTCctg actgctTtgc tgcttgcagc


 


51
gtgcGGCGGT Tcggacaaac cgcctgccga Aaaaccggca ccggcgGaAA


 


101
accaaAacgt atTgaAAATT TataACTGGT CGGAATACGT CGATCCGGAA


 


151
ACCGTTGCCG ATTTTGAAAA GAAAAACGGC ATCAAGGTTA CTTATGATGT


 


201
GTACGACAGT GATGAAACGC TGGAAAGCAA GGTGCTGACC GGAAAATCCG


 


251
GTTACGACAT TGTCGCGCCG TCCAATGCGT TTGTGGGCAG GCAGATTAAG


 


301
GCAGGTGCGT ATCAGAAAAT CGATAAGTCG ATGATTCCCA ATTATAAACA


 


351
TCTCAACCCT GAAATGATGA GGCTGATGGA CGGGGTCGAT CCCGACCACG


 


401
AATACGCCGT GCCGTTTTAT TGGGGGACAA ATACCTTCGC CATCAATACC


 


451
GAACGCGTGA AAAAGGCTTT GGGTACGGAC AAGCTGCCGG ACAACCAGTG


 


501
GGATTTGGTG TTCAACCCCG AATACACGTT CAAACTCAAA CAATGCGGCA


 


551
TCAGCTATTT GGACAGCGCG GCGGAAATTT ATCCCATGGT GTTGAACTAT


 


601
TTGGGCAAAA ACCCGAACAG CAGCAATACG GAAGACATCA GGGAGGCAAC


 


651
CGCCCTGCTC AAGAAAAACC GCCCCAATAT CAAACGCTTT ACTTCGTCCG


 


701
GCTTTATCGA TGATTTGGCG CGCGGCGATA CCTGCGTAAC AATCGGTTTC


 


751
GGCGGAGATT TGAACATCGC CAAACGCCGT GCCGAAGAAG CGGGCGGCAA


 


801
GGAAAAAATC CGCGTGATGA TGCCGAAAGA GGGCGTGGGG ATTTGGGTGG


 


851
ATTCTTTCGT GATTCCGAAA GATGCGAAAA ACGTCGCCAA CGCGCACAAA


 


901
TACATCAACG ACTTCCTCGA TCCGGAAGTG TCGGCGAAAA ACGGCAATTT


 


951
cgttacCTAC GCGCCTTCGA GCAAGCCGGC GCGCGATTTG ATGGAGGACG


 


1001
AATTTAAAAA CGACAATACG ATTTTCCCGA GCGGGGAAGA TTTGAAAAAC


 


1051
AGCTTTATCA TGGTGCCTAT CCGGCCGGCG GCATTGAAGT TTATGGTGCG


 


1101
CCAGTGGCAG GATGTGAAGG CGGGGAAATA A






This corresponds to the amino acid sequence <SEQ ID 2784; ORF 917.ng>:










g917.pep




1
MVKHLPLAVL TALLLAACGG SDKPPAEKPA PAENQNVLKI YNWSEYVDPE


 


51
TVADFEKKNG IKVTYDVYDS DETLESKVLT GKSGYDIVAP SNAFVGRQIK


 


101
AGAYQKIDKS MIPNYKHLNP EMMRLMDGVD PDHEYAVPFY WGTNTFAINT


 


151
ERVKKALGTD KLPDNQWDLV FNPEYTFKLK QCGISYLDSA AEIYPMVLNY


 


201
LGKNPNSSNT EDIREATALL KKNRPNIKRF TSSGFIDDLA RGDTCVTIGF


 


251
GGDLNIAKRR AEEAGGKEKI RVMMPKEGVG IWVDSFVIPK DAKNVANAHK


 


301
YINDFLDPEV SAKNGNFVTY APSSKPARDL MEDEFKNDNT IFPSGEDLKN


 


351
SFIMVPIRPA ALKFMVRQWQ DVKAGK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2785>:










m917.seq




1
ATGACCAAAC ATCTGCCCCT GGCCGTCCTG ACTGCTTTGC TGCTTGCAGC


 


51
GTGCGGCGGT TCGGACAAAC CGCCTGCCGA AAAACCGGCA CCGGCGGAAA


 


101
ACCAAAACGT ATTGAAAATT TACAACTGGT CGGAATATGT CGATCCGGAA


 


151
ACCGTTGCCG ATTTTGAAAA GAAAAACGGC ATCAAGGTTA CTTATGATGT


 


201
GTACGACAGC GATGAAACGC TGGAAAGCAA GGTGCTGACA GGCAAGTCCG


 


251
GTTACGACAT TGTCGCGCCG TCCAATGCGT TTGTGGGCAG GCAGATTAAG


 


301
GCAGGTGCGT ATCAGAAAAT CGATAAGTCG CTGATTCCCA ATTATAAACA


 


351
CCTCAACCCC GAAATGATGA GGCTGATGGA CGGGGTCGAT CCCGGCCACG


 


401
AATACGCCGT GCCGTTTTAT TGGGGGACAA ATACCTTCGC CATCAATACC


 


451
GAACGCGTGA AAAAGGCTTT GGGTACGGAC AAGCTGCCGG ACAACCAGTG


 


501
GGATTTGGTG TTCGACCCCG AATACACGTC CAAACTCAAG CAATGCGGCA


 


551
TCAGCTATTT GGACAGCGCG GCGGAAATCT ATCCTATGGT GTTGAACTAT


 


601
TTGGGTAAAA ACCCGAACAG CAGCAATACG GAAGACATCA GGGAGGCAAC


 


651
CGCCCTACTC AAGAAAAACC GCCCCAATAT CAAACGCTTT ACTTCGTCCG


 


701
GCTTTATCGA TGATTTGGCG CGCGGCGATA CCTGCGTAAC AATCGGTTTC


 


751
GGCGGCGATT TGAACATCGC CAAACGCCGT GCCGAAGAAG CGGGCGGCAA


 


801
GGAAAAAATC CGCGTGATGA TGCCCAAAGA GGGCGTGGGG ATTTGGGTGG


 


851
ATTCTTTCGT GATTCCGAAA GATGCGAAAA ACGTCGCCAA CGCGCACAAA


 


901
TACATCAACG ACTTCCTCGA CCCGGAAGTG TCGGCGAAAA ACGGCAATTT


 


951
CGTTACTTAC GCGCCTTCGA GCAAGCCTGC GCGTGAGCTG ATGGAAGACG


 


1001
AATTTAAAAA CGACAATACG ATTTTCCCAA CCGAGGAGGA TTTGAAAAAC


 


1051
AGCTTTATCA TGGTGCCTAT CCAGCCGGCG GCATTGAAGT TTATGGTGCG


 


1101
CCAGTGGCAG GATGTGAAGG CGGGGAAATA A






This corresponds to the amino acid sequence <SEQ ID 2786; ORF 917>:










m917.pep




1
MTKHLPLAVL TALLLAACGG SDKPPAEKPA PAENQNVLKI YNWSEYVDPE


 


51
TVADFEKKNG IKVTYDVYDS DETLESKVLT GKSGYDIVAP SNAFVGRQIK


 


101
AGAYQKIDKS LIPNYKHLNP EMMRLMDGVD PGHEYAVPFY WGTNTFAINT


 


151
ERVKKALGTD KLPDNQWDLV FDPEYTSKLK QCGISYLDSA AEIYPMVLNY


 


201
LGKNPNSSNT EDIREATALL KKNRPNIKRF TSSGFIDDLA RGDTCVTIGF


 


251
GGDLNIAKRR AEEAGGKEKI RVMMPKEGVG IWVDSFVIPK DAKNVANAHK


 


301
YINDFLDPEV SAKNGNFVTY APSSKPAREL MEDEFKNDNT IFPTEEDLKN


 


351
SFIMVPIQPA ALKFMVRQWQ DVKAGK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 917 shows 97.6% identity over a 376 aa overlap with a predicted ORF (ORF 917.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2787>:










a917.seq




1
ATGACCAAAC ATCTGCCCCT GGCCGTCCTG ACTGCTTTGC TGCTTGCAGC


 


51
GTGCGGCGGT TCGGACAAAC CGCCTGCCGA AAAACCGGCG CCGGCGGAAA


 


101
ACCGAAACGT ATTGAAAATT TACAACTGGT CGGAATACGT CGATCCGGAA


 


151
ACCGTTGCCG ATTTTGAAAA GAAAAACGGC ATCAAGGTTA CTTATGATGT


 


201
GTACGACAGC GATGAAACGC TGGAAAGCAA GGTGCTGACC GGAAAATCTG


 


251
GTTACGACAT TGTCGCGCCG TCCAATGCGT TTGTGGGCAG GCAGATTAAG


 


301
GCAGGTGCGT ATCAGAAAAT CGATAAGTCG CTGATTCCCA ATTATAAACA


 


351
CCTCAACCCC GAAATGATGA GGCTGATGGA CGGGGTCGAT CCCGGCCACG


 


401
AATACGCCGT GCCGTTTTAT TGGGGGACAA ATACCTTCGC CATCAATACC


 


451
GAACGCGTGA AAAAGGCTTT GGGTACGGAC AAGCTGCCGG ACAACCAGTG


 


501
GGATTTGGTG TTCGACCCCG AATACACGTC CAAACTCAAG CAATGCGGCA


 


551
TCAGCTATTT GGACAGCGCG GCGGAAATCT ATCCTATGGT GTTGAACTAT


 


601
TTGGGTAAAA ACCCGAACAG CAGCAATACG GAAGACATCA GGGAGGCAAC


 


651
CGCCCTACTC AAGAAAAACC GCCCCAATAT CAAACGCTTT ACTTCGTCCG


 


701
GCTTTATCGA TGATTTGGCG CGCGGCGATA CCTGCGTAAC AATCGGTTTC


 


751
GGCGGCGATT TGAACATCGC CAAACGCCGT GCCGAAGAAG CGGGCGGCAA


 


801
GGAAAAAATC CGCGTGATGA TGCCCAAAGA GGGCGTGGGG ATTTGGGTGG


 


851
ATTCTTTCGT GATTCCGAAA GATGCGAAAA ACGTCGCCAA CGCGCACAAA


 


901
TACATCAACG ACTTCCTCGA CCCGGAAGTG TCGGCGAAAA ACGGCAATTT


 


951
CGTTACTTAC GCGCCTTCGA GCAAGCCTGC GCGTGAGCTG ATGGAAGACG


 


1001
AATTTAAAAA CGACAATACG ATTTTCCCAA CCGAGGAGGA TTTGAAAAAC


 


1051
AGCTTTATCA TGGTGCCTAT CCAGCCGGCG GCATTGAAGT TTATGGTGCG


 


1101
CCAGTGGCAG GATGTGAAGG CGGGGAAATA A






This corresponds to the amino acid sequence <SEQ ID 2788; ORF 917.a>:










a917.pep




1
MTKHLPLAVL TALLLAACGG SDKPPAEKPA PAENRNVLKI YNWSEYVDPE


 


51
TVADFEKKNG IKVTYDVYDS DETLESKVLT GKSGYDIVAP SNAFVGRQIK


 


101
AGAYQKIDKS LIPNYKHLNP EMMRLMDGVD PGHEYAVPFY WGTNTFAINT


 


151
ERVKKALGTD KLPDNQWDLV FDPEYTSKLK QCGISYLDSA AEIYPMVLNY


 


201
LGKNPNSSNT EDIREATALL KKNRPNIKRF TSSGFIDDLA RGDTCVTIGF


 


251
GGDLNIAKRR AEEAGGKEKI RVMMPKEGVG IWVDSFVIPK DAKNVANAHK


 


301
YINDFLDPEV SAKNGNFVTY APSSKPAREL MEDEFKNDNT IFPTEEDLKN


 


351
SFIMVPIQPA ALKFMVRQWQ DVKAGK*






m917/a917 99.7% identity in 376 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2789>:










g919.seq




1
ATGAAAAAAC ACCTGCTCCG CTCCGCCCTG TACGGcatCG CCGCCgccAT


 


51
CctcgCCGCC TGCCAAAgca gGAGCATCCA AACCTTTCCG CAACCCGACA


 


101
CATCCGTCAT CAACGGCCCG GACCGGCCGG CCGGCATCCC CGACCCCGCC


 


151
GGAACGACGG TTGCCGGCGG CGGGGCCGTC TATACCGTTG TGCCGCACCT


 


201
GTCCATGCCC CACTGGGCGG CGCaggATTT TGCCAAAAGC CTGCAATCCT


 


251
TCCGCCTCGG CTGCGCCAAT TTGAAAAACC GCCAAGGCTG GCAGGATGTG


 


301
TGCGCCCAAG CCTTTCAAAC CCCCGTGCAT TCCTTTCAGG CAAAGcGgTT


 


351
TTTTGAACGC TATTTCACGC cgtGGCaggt tgcaggcaAC GGAAGcCTTG


 


401
Caggtacggt TACCGGCTAT TACGAACCGG TGCTGAAGGG CGACGGCAGG


 


451
CGGACGGAAC GGGCCCGCTT CCCGATTTAC GGTATTCCCG ACGATTTTAT


 


501
CTCCGTCCCG CTGCCTGCCG GTTTGCGGGG CGGAAAAAAC CTTGTCCGCA


 


551
TCAGGCAGac ggGGAAAAAC AGCGGCACGA TCGACAATGC CGGCGGCACG


 


601
CATACCGCCG ACCTCTCCCG ATTCCCCATC ACCGCGCGCA CAACGGcaat


 


651
caaaGGCAGG TTTGAaggAA GCCGCTTCCT CCCTTACCAC ACGCGCAACC


 


701
AAAtcaacGG CGGCgcgcTT GACGGCAAag cccCCATCCT CggttacgcC


 


751
GAagaccCcG tcgaacttTT TTTCATGCAC AtccaaggCT CGGGCCGCCT


 


801
GAAAACCCcg tccggcaaat acatCCGCAt cggaTacgcc gacAAAAACG


 


851
AACAtccgTa tgtttccatc ggACGctaTA TGGCGGACAA AGGCTACCTC


 


901
AAGctcgggc agACCTCGAT GCAGGgcatc aaagcCTATA TGCGGCAAAA


 


951
TCCGCAACGC CTCGCCGAAG TTTTGGGTCA AAACCCCAGC TATATCTTTT


 


1001
TCCGCGAGCT TGCCGGAAGC GGCAATGAGG GCCCCGTCGG CGCACTGGGC


 


1051
ACGCCACTGA TGGGGGAATA CGCCGGCGCA ATCGACCGGC ACTACATTAC


 


1101
CTTGGGCGCG CCCTTATTTG TCGCCACCGC CCATCCGGTT ACCCGCAAAG


 


1151
CCCTCAACCG CCTGATTATG GCGCAGGATA CAGGCAGCGC GATCAAAGGC


 


1201
GCGGTGCGCG TGGATTATTT TTGGGGTTAC GGCGACGAAG CCGGCGAACT


 


1251
TGCCGGCAAA CAGAAAACCA CGGGATACGT CTGGCAGCTC CTGCCCAACG


 


1301
GCATGAAGCC CGAATACCGC CCGTGA






This corresponds to the amino acid sequence <SEQ ID 2790; ORF 919.ng>:










g919.pep




1
MKKHLLRSAL YGIAAAILAA CQSRSIQTFP QPDTSVINGP DRPAGIPDPA


 


51
GTTVAGGGAV YTVVPHLSMP HWAAQDFAKS LQSFRLGCAN LKNRQGWQDV


 


101
CAQAFQTPVH SFQAKRFFER YFTPWQVAGN GSLAGTVTGY YEPVLKGDGR


 


151
RTERARFPIY GIPDDFISVP LPAGLRGGKN LVRIRQTGKN SGTIDNAGGT


 


201
HTADLSRFPI TARTTAIKGR FEGSRFLPYH TRNQINGGAL DGKAPILGYA


 


251
EDPVELFFMH IQGSGRLKTP SGKYIRIGYA DKNEHPYVSI GRYMADKGYL


 


301
KLGQTSMQGI KAYMRQNPQR LAEVLGQNPS YIFFRELAGS GNEGPVGALG


 


351
TPLMGEYAGA IDRHYITLGA PLFVATAHPV TRKALNRLIM AQDTGSAIKG


 



AVRVDYFWGY GDEAGELAGK QKTTGYVWQL LPNGMKPEYR P*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2791>:










m919.seq




1
ATGAAAAAAT ACCTATTCCG CGCCGCCCTG TACGGCATCG CCGCCGCCAT


 


51
CCTCGCCGCC TGCCAAAGCA AGAGCATCCA AACCTTTCCG CAACCCGACA


 


101
CATCCGTCAT CAACGGCCCG GACCGGCCGG TCGGCATCCC CGACCCCGCC


 


151
GGAACGACGG TCGGCGGCGG CGGGGCCGTC TATACCGTTG TACCGCACCT


 


201
GTCCCTGCCC CACTGGGCGG CGCAGGATTT CGCCAAAAGC CTGCAATCCT


 


251
TCCGCCTCGG CTGCGCCAAT TTGAAAAACC GCCAAGGCTG GCAGGATGTG


 


301
TGCGCCCAAG CCTTTCAAAC CCCCGTCCAT TCCTTTCAGG CAAAACAGTT


 


351
TTTTGAACGC TATTTCACGC CGTGGCAGGT TGCAGGCAAC GGAAGCCTTG


 


401
CCGGTACGGT TACCGGCTAT TACGAACCGG TGCTGAAGGG CGACGACAGG


 


451
CGGACGGCAC AAGCCCGCTT CCCGATTTAC GGTATTCCCG ACGATTTTAT


 


501
CTCCGTCCCC CTGCCTGCCG GTTTGCGGAG CGGAAAAGCC CTTGTCCGCA


 


551
TCAGGCAGAC GGGAAAAAAC AGCGGCACAA TCGACAATAC CGGCGGCACA


 


601
CATACCGCCG ACCTCTCCcG ATTCCCCATC ACCGCGCGCA CAACAGCAAT


 


651
CAAAGGCAGG TTTGAAGGAA GCCGCTTCCT CCCCTACCAC ACGCGCAACC


 


701
AAATCAACGG CGGCGCGCTT GACGGCAAAG CCCCGATACT CGGTTACGCC


 


751
GAAGACCCTG TCGAACTTTT TTTTATGCAC ATCCAAGGCT CGGGCCGTCT


 


801
GAAAACCCCG TCCGGCAAAT ACATCCGCAT CGGCTATGCC GACAAAAACG


 


851
AACATCCyTA CGTTTCCATC GGACGCTATA TGGCGGATAA GGGCTACCTC


 


901
AAACTCGGAC AAACCTCCAT GCAGGGCATT AAGTCTTATA TGCGGCAAAA


 


951
TCCGCAACGC CTCGCCGAAG TTTTGGGTCA AAACCCCAGC TATATCTTTT


 


1001
TCCGCGAGCT TGCCGGAAGC AGCAATGACG GCCCTGTCGG CGCACTGGGC


 


1051
ACGCCGCTGA TGGGGGAATA TGCCGGCGCA GTCGACCGGC ACTACATTAC


 


1101
CTTGGGTGCG CCCTTATTTG TCGCCACCGC CCATCCGGTT ACCCGCAAAG


 


1151
CCCTCAACCG CCTGATTATG GCGCAGGATA CCGGCAGCGC GATTAAAGGC


 


1201
GCGGTGCGCG TGGATTATTT TTGGGGATAC GGCGACGAAG CCGGCGAACT


 


1251
TGCCGGCAAA CAGAAAACCA CGGGATATGT CTGGCAGCTC CTACCCAACG


 



GTATGAAGCC CGAATACCGc CCGTAA






This corresponds to the amino acid sequence <SEQ ID 2792; ORF 919>:










m919.pep




1
MKKYLFRAAL YGIAAAILAA CQSKSIQTFP QPDTSVINGP DRPVGIPDPA


 


51
GTTVGGGGAV YTVVPHLSLP HWAAQDFAKS LQSFRLGCAN LKNRQGWQDV


 


101
CAQAFQTPVH SFQAKQFFER YFTPWQVAGN GSLAGTVTGY YEPVLKGDDR


 


151
RTAQARFPIY GIPDDFISVP LPAGLRSGKA LVRIRQTGKN SGTIDNTGGT


 


201
HTADLSRFPI TARTTAIKGR FEGSRFLPYH TRNQINGGAL DGKAPILGYA


 


251
EDPVELFFMH IQGSGRLKTP SGKYIRIGYA DKNEHPYVSI GRYMADKGYL


 


301
KLGQTSMQGI KSYMRQNPQR LAEVLGQNPS YIFFRELAGS SNDGPVGALG


 


351
TPLMGEYAGA VDRHYITLGA PLFVATAHPV TRKALNRLIM AQDTGSAIKG


 


401
AVRVDYFWGY GDEAGELAGK QKTTGYVWQL LPNGMKPEYR P*






    
    
        Computer analysis of this amino acid sequence gave the following results:
        Homology with a predicted ORF from N. gonorrhoeae 
        ORF 919 shows 95.9% identity over a 441 aa overlap with a predicted ORF (ORF 919.ng) from N. gonorrhoeae: 
        m919/g919
    
    






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2793>:










a919.seq




1
ATGAAAAAAT ACCTATTCCG CGCCGCCCTG TGCGGCATCG CCGCCGCCAT


 


51
CCTCGCCGCC TGCCAAAGCA AGAGCATCCA AACCTTTCCG CAACCCGACA


 


101
CATCCGTCAT CAACGGCCCG GACCGGCCGG TCGGCATCCC CGACCCCGCC


 


151
GGAACGACGG TCGGCGGCGG CGGGGCCGTT TATACCGTTG TGCCGCACCT


 


201
GTCCCTGCCC CACTGGGCGG CGCAGGATTT CGCCAAAAGC CTGCAATCCT


 


251
TCCGCCTCGG CTGCGCCAAT TTGAAAAACC GCCAAGGCTG GCAGGATGTG


 


301
TGCGCCCAAG CCTTTCAAAC CCCCGTCCAT TCCGTTCAGG CAAAACAGTT


 


351
TTTTGAACGC TATTTCACGC CGTGGCAGGT TGCAGGCAAC GGAAGCCTTG


 


401
CCGGTACGGT TACCGGCTAT TACGAGCCGG TGCTGAAGGG CGACGACAGG


 


451
CGGACGGCAC AAGCCCGCTT CCCGATTTAC GGTATTCCCG ACGATTTTAT


 


501
CTCCGTCCCC CTGCCTGCCG GTTTGCGGAG CGGAAAAGCC CTTGTCCGCA


 


551
TCAGGCAGAC GGGAAAAAAC AGCGGCACAA TCGACAATAC CGGCGGCACA


 


601
CATACCGCCG ACCTCTCCCA ATTCCCCATC ACTGCGCGCA CAACGGCAAT


 


651
CAAAGGCAGG TTTGAAGGAA GCCGCTTCCT CCCCTACCAC ACGCGCAACC


 


701
AAATCAACGG CGGCGCGCTT GACGGCAAAG CCCCGATACT CGGTTACGCC


 


751
GAAGACCCCG TCGAACTTTT TTTTATGCAC ATCCAAGGCT CGGGCCGTCT


 


801
GAAAACCCCG TCCGGCAAAT ACATCCGCAT CGGCTATGCC GACAAAAACG


 


851
AACATCCCTA CGTTTCCATC GGACGCTATA TGGCGGACAA AGGCTACCTC


 


901
AAGCTCGGGC AGACCTCGAT GCAGGGCATC AAAGCCTATA TGCAGCAAAA


 


951
CCCGCAACGC CTCGCCGAAG TTTTGGGGCA AAACCCCAGC TATATCTTTT


 


1001
TCCGAGAGCT TACCGGAAGC AGCAATGACG GCCCTGTCGG CGCACTGGGC


 


1051
ACGCCGCTGA TGGGCGAGTA CGCCGGCGCA GTCGACCGGC ACTACATTAC


 


1101
CTTGGGCGCG CCCTTATTTG TCGCCACCGC CCATCCGGTT ACCCGCAAAG


 


1151
CCCTCAACCG CCTGATTATG GCGCAGGATA CCGGCAGCGC GATTAAAGGC


 


1201
GCGGTGCGCG TGGATTATTT TTGGGGATAC GGCGACGAAG CCGGCGAACT


 


1251
TGCCGGCAAA CAGAAAACCA CGGGATATGT CTGGCAGCTT CTGCCCAACG


 


1301
GTATGAAGCC CGAATACCGC CCGTAA






This corresponds to the amino acid sequence <SEQ ID 2794; ORF 919.a>:










a919.pep




1
MKKYLFRAAL CGIAAAILAA CQSKSIQTFP QPDTSVINGP DRPVGIPDPA


 


51
GTTVGGGGAV YTVVPHLSLP HWAAQDFAKS LQSFRLGCAN LKNRQGWQDV


 


101
CAQAFQTPVH SVQAKQFFER YFTPWQVAGN GSLAGTVTGY YEPVLKGDDR


 


151
RTAQARFPIY GIPDDFISVP LPAGLRSGKA LVRIRQTGKN SGTIDNTGGT


 


201
HTADLSQFPI TARTTAIKGR FEGSRFLPYH TRNQINGGAL DGKAPILGYA


 


251
EDPVELFFMH IQGSGRLKTP SGKYIRIGYA DKNEHPYVSI GRYMADKGYL


 


301
KLGQTSMQGI KAYMQQNPQR LAEVLGQNPS YIFFRELTGS SNDGPVGALG


 


351
TPLMGEYAGA VDRHYITLGA PLFVATAHPV TRKALNRLIM AQDTGSAIKG


 


401
AVRVDYFWGY GDEAGELAGK QKTTGYVWQL LPNGMKPEYR P*






m919/a919 98.6% identity in 441 aa overlap




Expression of ORF 919
The primer described in Example 1 for ORF 919 was used to locate and clone ORF 919. This sequence was purified and expressed in E. coli as provided in FIG. 1 #. The hydrophilicity plots, antigenic index, and amphipatic regions of ORF 919 is provided in FIG. 5 #. The AMPHI program is used to predict putative T-cell epitopes (Gao et al 1989, J. Immunol. 143:3007; Roberts et al. 1996, AIDS Res Human Retroviruses 12:593; Quakyi et al. 1992, Scand J Immunol Suppl 11:9). The nucleic acid sequence of ORF 919 is provided in Exhibit C #.
The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2795>:








g920.seq (partial)










1
..ccgatgcagc tggttaccga aaaAGGTAAG GAAAACATGA TTCAACGCGG



 


51
  CACATACAAC TACCAATACC GCAGCAACCG TCCGGTCAAA GACGGCAGCT


 


101
  ACCTCGTTAC CGCCGAATAT CAGCCTACTT TCCGGTCAAA AAACAAAGCA


 


151
  GGCTGGAAAC AGGCTGGCAT CAAAGAAATG CCTGACGCAA GCTATTGCGA


 


201
  ACAAACCCGT ATGTTCGGTA AAAACATTGT CAACGTGGGA CACGAAAGCG


 


251
  CGGACACCGC CATCATCACC AAACCGGTCG GACAAAACTT GGAAATCGTC


 


301
  CCGCTGGACA ATCccgccga caTTCACgtg ggctaacgCt tcaaaGTccg


 


351
  cgttCtgttc cgtGGCgaac cgCTGcccaa tgccACCgtt accgCtacAT


 


401
  TTGacggctt cGAcaccagc gaccgcagca aaacgcacaa Aaccgaagcc


 


451
  caagcctTCT ccgacaccac cgacggcgaa ggcgaagtgg acatcatCCC


 


501
  CTTGCgccaa GGCTTttgga aAgcGAGTGT CGAATAcaaa gccgAtttcc


 


551
  CCGATcaaAG CCTGTGccga AAACAggcgA ACTACaCaac TTtaaccttc


 


601
  caaatcgccc attctCacca tTAa






This corresponds to the amino acid sequence <SEQ ID 2796; ORF 920.ng>:









g920.pep (partial)










1
..PMQLVTEKGK ENMIQRGTYN YQYRSNRPVK DGSYLVTAEY QPTFRSKNKA



 


51
  GWKQAGIKEM PDASYCEQTR MFGKNIVNVG HESADTAIIT KPVGQNLEIV


 


101
  PLDNPADIHV GXRFKVRVLF RGEPLPNATV TATFDGFDTS DRSKTHKTEA


 


151
  QAFSDTTDGE GEVDIIPLRQ GFWKASVEYK ADFPDQSLCR KQANYTTLTF


 


201
  QIAHSHH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2797>:










m920.seq




1
ATGAAGAAAA CATTGACACT GCTCTCCGTT TCCGCCCTAT TTGCCACATC


 


51
CGCCCACGCC CACCGmGTCT GGGTCGAAAC CGCCCACACG CACGGCGGCG


 


101
AATACCTTAA AGCCGACTTG GGCTACGGCG AATTTCCCGA ACTCGAACCC


 


151
ATCGCCAAAG ACCGCCTGCA CATCTTCAGC AAACCGATGC AGCTGGTTAC


 


201
CGAAAAAGGC AAGGAAAACA TGATTCAACG CGGCACATAC AACTACCAGT


 


251
ACCGAAGCAA CCGTCCCGTT AAGGACGGCA GTTACCTCGT CATCGCCGAA


 


301
TATCAGCCTA CTTTCTGGTC AAAAwACAAA GCAGGCTGGA AACAGGCGGG


 


351
CATCAAAGAA ATGCCTGACG CAAGCTATTG CGAACAAACC CGAATGTTCG


 


401
GCAAAAACAT CGTCAACGTC GGACACGAAA GCGCGGACAC CGCCATCATC


 


451
ACCAArCCGG TCGGACAAAA CTTGGAAATC GTCCCGCTGG ACAATCCCGC


 


501
CAACATTCAC GTAGGCGAAC GCTTCAAAGT CCGCGTTCTG TTCCGTGGCG


 


551
AACCGCTGCC CAATGCCACC GTTACCGCCA CCTTTGACGG CTTCGACACC


 


601
AGCGACCGCA GCAAAACGCA CAAwmCCGAA GCACAGGCTT TCTCCGACAG


 


651
CACAGACGAC AAAGGCGAAG TGGACATCAT CmCCTTGCGC CAAGGCTTCT


 


701
GGAAAGCCAA TGTCGAACAC AAAACCGACT TCCCCGATCA AAGCGTGTGC


 


751
CAAAAACAGG CGAACTACTC GACTTTAACC TTCCAAATCG GTCATTCGCA


 


801
CCATTAA






This corresponds to the amino acid sequence <SEQ ID 2798; ORF 920>:










m920.pep




1
MKKTLTLLSV SALFATSAHA HRVWVETAHT HGGEYLKADL GYGEFPELEP


 


51
IAKDRLHIFS KPMQLVTEKG KENMIQRGTY NYQYRSNRPV KDGSYLVIAE


 


101
YQPTFWSKXK AGWKQAGIKE MPDASYCEQT RMFGKNIVNV GHESADTAII


 


151
TKPVGQNLEI VPLDNPANIH VGERFKVRVL FRGEPLPNAT VTATFDGFDT


 


201
SDRSKTHXXE AQAFSDSTDD KGEVDIIXLR QGFWKANVEH KTDFPDQSVC


 


251
QKQANYSTLT FQIGHSHH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 920 shows 91.3% identity over a 207 aa overlap with a predicted ORF (ORF 920.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2799>:










a920.seq




1
TGAAAGAAAA CATTGACACT GCTCGCCGTT TCCGCCCTAT TTGCCGCATC


 


51
CGCCCACGCC CACCGCGTCT GGGTCGAAAC CGCCCACACG CACGGCGGCG


 


101
AATACCTTAA AGCCGACTTG GGCTACGGCG AATTTCCCGA ACTCGAACCC


 


151
ATCGCCAAAG ACCGCCTGCA CATCTTCAGC AAACCGATGC AGCTGGTTAC


 


201
CGAAAAAGGC AAGGAAAACA TGATTCAACG CGGCACATAC AACTACCAGT


 


251
ACCGAAGCAA CCGTCCCGTT AAGGACGGCA GTTACCTCGT CATCGCCGAA


 


301
TATCAGCCTA CTTTCTGGTC AAAAAACAAA GCAGGCTGGA AACAGGCGGG


 


351
CATCAAACAA ATGCCTGACG CAAGCTATTG CGAACAAACC CGAATGTTCG


 


401
GCAAAAACAT CGTCAACGTC GGACACGAAA GCGCGGACAC CGCCATCATC


 


451
ACCAAACCGG TCGGACAAAA CTTGGAAATC GTCCCGCTGG ACAATCCCGC


 


501
CAACATTCAC GTAGGCGAAC GCTTCAAAGT CCGCGTTCTG TTCCGTGGCG


 


551
AACCGCTGCC CAATGCCACC GTTACCGCCA CCTTTGACGG CTTCGACACC


 


601
AGCGACCGCA GCAAAACGCA CAAAACCGAA GCACAGGCTT TCTCCGACAG


 


651
CACAGACGAC AAAGGCGAAG TGGACATCAT CCCCTTGCGC CAAGGCTTCT


 


701
GGAAAGCCAA TGTCGAACAC AAAGCCGACT TCCCCGATCA AAGCGTGTGC


 


751
CAAAAACAGG CGAACTACTC GACTTTAACC TTCCAAATCG GCCATTCGCA


 


801
CCATTAA






This corresponds to the amino acid sequence <SEQ ID 2800; ORF 920.a>:










a920.pep




1
*KKTLTLLAV SALFAASAHA HRVWVETAHT HGGEYLKADL GYGEFPELEP


 


51
IAKDRLHIFS KPMQLVTEKG KENMIQRGTY NYQYRSNRPV KDGSYLVIAE


 


101
YQPTFWSKNK AGWKQAGIKQ MPDASYCEQT RMFGKNIVNV GHESADTAII


 


151
TKPVGQNLEI VPLDNPANIH VGERFKVRVL FRGEPLPNAT VTATFDGFDT


 


201
SDRSKTHKTE AQAFSDSTDD KGEVDIIPLR QGFWKANVEH KADFPDQSVC


 


251
QKQANYSTLT FQIGHSHH*






m920/a920 97.0% identity in 267 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2801>:










g920-1.seq




1
ATGAAGAAAA CATTGACACT GCTCGCcgtt TcCGCACTAT TTGCCACATc


 


51
cgCaCACCCC CACCgCGTCT GGGTCGAAAC CgccCACACg cAcgGCGGCG


 


101
AATACCTTAA AGCCGACTTG GGCTACGGCG AATTCCCCGA ACTCGAACCC


 


151
ATCGccAAAG ACCgccTGCA CATCTTCAGC AAACCGATGC AGCTGGTTAC


 


201
CGAAAAAGGT AAGGAAAACA TGATTCAACG CGGCACATAC AACTACCAAT


 


251
ACCGCAGCAA CCGTCCCGTC AAAGACGGCA GCTACCTCGT TACCGCCGAA


 


301
TATCAGCCTA CTTTCCGGTC AAAAAACAAA GCAGGCTGGA AACAGGCTGG


 


351
CATCAAAGAA ATGCCTGACG CAAGCTATTG CGAACAAACC CGTATGTTCG


 


401
GTAAAAACAT TGTCAACGTG GGACACGAAA GCGCGGACAC CGCCATCATC


 


451
ACCAAACCGG TCGGACAAAA CTTGGAAATC GTCCCGCTGG ACAATCCCGC


 


501
CAACATTCAC GTAGGCGAAC GCTTCAAAGT CCGCGTTCTG TTCCGTGGCG


 


551
AACCGCTGCC CAATGCCACC GTTACCGCTA CATTTGACGG CTTCGACACC


 


601
AGCGACCGCA GCAAAACGCA CAAAACCGAA GCCCAAGCCT TCTCCGACAC


 


651
CACCGACGGC AAAGGCGAAG TGGACATCAT CCCCTTGCGC CAAGGCTTTT


 


701
GGAAAGCGAG TGTCGAATAC AAAGCCGATT TCCCCGATCA AAGCCTGTGC


 


751
CAAAAACAGG CGAACTACAC AACTTTAACC TTCCAAATCG GCCATTCTCA


 


801
CCATTAA






This corresponds to the amino acid sequence <SEQ ID 2802; ORF 920-1.ng>:










g920-1.pep




1
MKKTLTLLAV SALFATSAHP HRVWVETAHT HGGEYLKADL GYGEFPELEP


 


51
IAKDRLHIFS KPMQLVTEKG KENMIQRGTY NYQYRSNRPV KDGSYLVTAE


 


101
YQPTFRSKNK AGWKQAGIKE MPDASYCEQT RMFGKNIVNV GHESADTAII


 


151
TKPVGQNLEI VPLDNPANIH VGERFKVRVL FRGEPLPNAT VTATFDGFDT


 


201
SDRSKTHKTE AQAFSDTTDG KGEVDIIPLR QGFWKASVEY KADFPDQSLC


 


251
QKQANYTTLT FQIGHSHH*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2803>:










m920-1.seq




1
ATGAAGAAAA CATTGACACT GCTCGCCGTT TCCGCCCTAT TTGCCACATC


 


51
CGCCCACGCC CACCGCGTCT GGGTCGAAAC CGCCCACACG CACGGCGGCG


 


101
AATACCTTAA AGCCGACTTG GGCTACGGCG AATTTCCCGA ACTCGAACCC


 


151
ATCGCCAAAG ACCGCCTGCA CATCTTCAGC AAACCGATGC AGCTGGTTAC


 


201
CGAAAAAGGC AAGGAAAACA TGATTCAACG CGGCACATAC AACTACCAGT


 


251
ACCGAAGCAA CCGTCCCGTT AAGGACGGCA GTTACCTCGT CATCGCCGAA


 


301
TATCAGCCTA CTTTCTGGTC AAAAAACAAA GCAGGCTGGA AACAGGCGGG


 


351
CATCAAAGAA ATGCCTGACG CAAGCTATTG CGAACAAACC CGAATGTTCG


 


401
GCAAAAACAT CGTCAACGTC GGACACGAAA GCGCGGACAC CGCCATCATC


 


451
ACCAAACCGG TCGGACAAAA CTTGGAAATC GTCCCGCTGG ACAATCCCGC


 


501
CAACATTCAC GTAGGCGAAC GCTTCAAAGT CCGCGTTCTG TTCCGTGGCG


 


551
AACCGCTGCC CAATGCCACC GTTACCGCCA CCTTTGACGG CTTCGACACC


 


601
AGCGACCGCA GCAAAACGCA CAAAACCGAA GCACAGGCTT TCTCCGACAG


 


651
CACAGACGAC AAAGGCGAAG TGGACATCAT CCCCTTGCGC CAAGGCTTCT


 


701
GGAAAGCCAA TGTCGAACAC AAAACCGACT TCCCCGATCA AAGCGTGTGC


 


751
CAAAAACAGG CGAACTACTC GACTTTAACC TTCCAAATCG GTCATTCGCA


 


801
CCATTAA






This corresponds to the amino acid sequence <SEQ ID 2804; ORF 920-1>:










m920-1.pep




1
MKKTLTLLAV SALFATSAHA HRVWVETAHT HGGEYLKADL GYGEFPELEP


 


51
IAKDRLHIFS KPMQLVTEKG KENMIQRGTY NYQYRSNRPV KDGSYLVIAE


 


101
YQPTFWSKNK AGWKQAGIKE MPDASYCEQT RMFGKNIVNV GHESADTAII


 


151
TKPVGQNLEI VPLDNPANIH VGERFKVRVL FRGEPLPNAT VTATFDGFDT


 


201
SDRSKTHKTE AQAFSDSTDD KGEVDIIPLR QGFWKANVEH KTDFPDQSVC


 


251
QKQANYSTLT FQIGHSHH*






m920-1/g920-1 96.3% identity in 268 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2805>:










a920.seq




1
TGAAAGAAAA CATTGACACT GCTCGCCGTT TCCGCCCTAT TTGCCGCATC


 


51
CGCCCACGCC CACCGCGTCT GGGTCGAAAC CGCCCACACG CACGGCGGCG


 


101
AATACCTTAA AGCCGACTTG GGCTACGGCG AATTTCCCGA ACTCGAACCC


 


151
ATCGCCAAAG ACCGCCTGCA CATCTTCAGC AAACCGATGC AGCTGGTTAC


 


201
CGAAAAAGGC AAGGAAAACA TGATTCAACG CGGCACATAC AACTACCAGT


 


251
ACCGAAGCAA CCGTCCCGTT AAGGACGGCA GTTACCTCGT CATCGCCGAA


 


301
TATCAGCCTA CTTTCTGGTC AAAAAACAAA GCAGGCTGGA AACAGGCGGG


 


351
CATCAAACAA ATGCCTGACG CAAGCTATTG CGAACAAACC CGAATGTTCG


 


401
GCAAAAACAT CGTCAACGTC GGACACGAAA GCGCGGACAC CGCCATCATC


 


451
ACCAAACCGG TCGGACAAAA CTTGGAAATC GTCCCGCTGG ACAATCCCGC


 


501
CAACATTCAC GTAGGCGAAC GCTTCAAAGT CCGCGTTCTG TTCCGTGGCG


 


551
AACCGCTGCC CAATGCCACC GTTACCGCCA CCTTTGACGG CTTCGACACC


 


601
AGCGACCGCA GCAAAACGCA CAAAACCGAA GCACAGGCTT TCTCCGACAG


 


651
CACAGACGAC AAAGGCGAAG TGGACATCAT CCCCTTGCGC CAAGGCTTCT


 


701
GGAAAGCCAA TGTCGAACAC AAAGCCGACT TCCCCGATCA AAGCGTGTGC


 


751
CAAAAACAGG CGAACTACTC GACTTTAACC TTCCAAATCG GCCATTCGCA


 


801
CCATTAA






This corresponds to the amino acid sequence <SEQ ID 2806; ORF 920-1.a>:










a920.pep




1
*KKTLTLLAV SALFAASAHA HRVWVETAHT HGGEYLKADL GYGEFPELEP


 


51
IAKDRLHIFS KPMQLVTEKG KENMIQRGTY NYQYRSNRPV KDGSYLVIAE


 


101
YQPTFWSKNK AGWKQAGIKQ MPDASYCEQT RMFGKNIVNV GHESADTAII


 


151
TKPVGQNLEI VPLDNPANIH VGERFKVRVL FRGEPLPNAT VTATFDGFDT


 


201
SDRSKTHKTE AQAFSDSTDD KGEVDIIPLR QGFWKANVEH KADFPDQSVC


 


251
QKQANYSTLT FQIGHSHH*






m920-1/a920 98.9% identity in 267 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2807>:










g921.seq




1
ATGAAAAAAT ACCTTATCCC TCTTTCCATT GCGGCAGTCC TTTCCGggtG


 


51
Ccagtctatt tatGtgccca cattgacggA aatccccgTg aatcccatca


 


101
ataCCgtcaa aacggaagCA CCTGCAAAAG GTTTTCGCCT CGCCCCTTCG


 


151
CATTGGGCGG ATGTTGCCAA AATCAGCGAT GAAGCGACGC GCTTGGGCTA


 


201
TCAGGTGGGT ATCGGTAAAA TGACCAAGGT TCAGGcgGCG CAATATCTGA


 


251
ACAACTTCAG AAAACGCCTG GTCGGACGCA ATGCCGTCGA TGACAGTATG


 


301
TATGAAATCT ACCTGCGTTC GGCGGTAGAC AGCCAGCGCG GCGAAATCAA


 


351
TACGGAACAG TCCAAGCTGT ATATCGAGAA TGCCTTGCGC GGCTGGCAGC


 


401
AGCGTtggAA AAATATGGAT GCCAAACCCG ATAATCCCGC ATTTACCAAC


 


451
TTTTTGATGG AAGTGATGAA GATGCAGCCC TTGAAATGA






This corresponds to the amino acid sequence <SEQ ID 2808; ORF 921.ng>:










g921.pep




1
MKKYLIPLSI AAVLSGCQSI YVPTLTEIPV NPINTVKTEA PAKGFRLAPS


 


51
HWADVAKISD EATRLGYQVG IGKMTKVQAA QYLNNFRKRL VGRNAVDDSM


 


101
YEIYLRSAVD SQRGEINTEQ SKLYIENALR GWQQRWKNMD AKPDNPAFTN


 


151
FLMEVMKMQP LK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2809>:










m921.seq




1
ATGAAAAAAT ACCTTATCCC TCTTTCCATT GCGGCAGTTC TTTCCGGCTG


 


51
CCAGTCTATT TATGTGCCCA CATTGACGGA AATCCCCGTG AATCCTATCA


 


101
ATACCGTCAA AACGGAAGCA CCTGCAAAAG GTTTCCGCCT TGCCTCTTCG


 


151
CATTGGACGG ATGTTGCCAA AATCAGCGAT GAAGCGACGC GCTTGGGCTA


 


201
TCAGGTGGGT ATCGGTAAAA TGACCAAGGT TCAGGCGGCG CAATATCTGA


 


251
ACAACTTCAG AAAACGCCTG GTCGGACGCA ATGCCGTCGA TGACAGTATG


 


301
TATGAAATCT ACCTGCGTTC GGCGATAGAC AGCCAGCGGG GCGCAATCAA


 


351
TACGGAACAG TCCAAGCTGT ATATCCAGAA TGCCTTGCGC GGCTGGCAGC


 


401
AGCGTTGGAA AAATATGGAT GTCAAACCCA ACAACCCCGC ATTTACCAAC


 


451
TTTTTGATGG AAGTGATGAA GATGCAGCCC TTGAAATGA






This corresponds to the amino acid sequence <SEQ ID 2810; ORF 921>:










m921.pep




1
MKKYLIPLSI AAVLSGCQSI YVPTLTEIPV NPINTVKTEA PAKGFRLASS


 


51
HWTDVAKISD EATRLGYQVG IGKMTKVQAA QYLNNFRKRL VGRNAVDDSM


 


101
YEIYLRSAID SQRGAINTEQ SKLYIQNALR GWQQRWKNMD VKPNNPAFTN


 


151
FLMEVMKMQP LK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 921 shows 95.7% identity over a 162 aa overlap with a predicted ORF (ORF 921.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2811>:










a921.seq




1
ATGAAAAAAT ACCTTATCCC TCTTTCCATT GTGGCAGTTC TTTCCGGCTG


 


51
CCAGTCTATT TATGTGCCCA CATTGACGGA AATCCCCGTG AATCCTATCA


 


101
ATACCGTCAA AACGGAAGCA CCTGCAAAAG GTTTCCGCCT TGCCTCTTCG


 


151
CATTGGACGG ATGTTGCCAA AATCAGCGAT GAAGCGACGC GCTTGGGCTA


 


201
TCAGGTGGGT ATCGGTAAAA TGACCAAGGT TCAGGCGGCG CAATATCTGA


 


251
ACAACTTCAG AAAACGCCTG GTCGGACGCA ATGCCGTCGA TGACAGTATG


 


301
TATGAAATCT ACCTGCGTTC GGCGATAGAC AGCCAGCGGG GCGCAATCAA


 


351
TACGGAACAG TCCAAGCTGT ATATCCAGAA TGCCTTGCGC GGCTGGCAGC


 


401
AGCGTTGGAA AAATATGGAT GTCAAACCCA ACAACCCCGC ATTTACCAAC


 


451
TTTTTGATGG AAGTGATGAA GATGCAGCCC TTGAAATGA






This corresponds to the amino acid sequence <SEQ ID 2812; ORF 921.a>:










a921.pep




1
MKKYLIPLSI VAVLSGCQSI YVPTLTEIPV NPINTVKTEA PAKGFRLASS


 


51
HWTDVAKISD EATRLGYQVG IGKMTKVQAA QYLNNFRKRL VGRNAVDDSM


 


101
YEIYLRSAID SQRGAINTEQ SKLYIQNALR GWQQRWKNMD VKPNNPAFTN


 


151
FLMEVMKMQP LK*






m921/a921 99.4% identity in 162 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2813>:










g922.seq




1
ATGGAAAAGA GAAAAATACT GCCGCTGGCA ATTTGTTTGG CGGCTTTGTC


 


51
TGCCTGTACG GCGATGGAGG CCCGCACACC CCGGGCAAAT GAAGCCCAAG


 


101
CCCCCCGCGC GGATGAAATG AAAAAAGAAA GCCGCCCCGC GTTTGACGCG


 


151
GCAGCCGTAC CGGTATCCGA CAGCGGGTTT GCCGCCAATG CAAATGTCCG


 


201
CCGTTTTGTG GACGATGAAG TCGGGAAAGG GGATTTTTCC CAGGCGGAAT


 


251
GGCAGGATTT TTTTGACAAA GCGGCTTACA AGGCGGACAT CGTCAAGATt


 


301
ATGCACCGAC CCTCCACATC GCGtCCGTGG TATGtgttcc gCacggGAAa


 


351
ttcGGgcagg gcgaaAtttc ACggcgCGCG Caggttttat GcggaaAacc


 


401
gcgcggttat cgatgatgtg gcgCAAAAat acggcgtGCC TGCCGAGCTT


 


451
ATCGTGGCGA TTATCGGGAT TGAAACGAAT TACGGCAAAA ATACGGGCAG


 


501
TTTCCGTGTG GCGGACGCAT TGGCGACTTT AGGCTTTGAT TATCCCCGCC


 


551
GCGCCGGGTT TTTCCAAAAA GAATTGGTCG AGCTTTTAAA GCTGGCAAAA


 


601
GAAGAAGGCG GTGATGTTTT CGCCTTTAAG GGCagcTATG CGGGTGCAAT


 


651
GGGTATGCCG CAATTTATGC CTTCGAGCTA CCGGAAATGG GCGGTGGATT


 


701
ATGAcgggga cggacatCGG GATATAtggg GCAACGTcgg tgatgtcgcg


 


751
gcatcggTTG CCAATTAtat gaagCAGCAC GGTTGGCGCA CgggcggtAA


 


801
AATGTTGGTG TCGGCGAcgt tggcgccggg tgcggATGTT CAggcAATCA


 


851
TTGGCGAAAA AACCGCCCTG ACGCGGACGG TGGCGGATTT GAaggCGTAc


 


901
ggcatcatcc ccggggaaaC GCTCGCAGAT GATGAAAAGg cgGTTTTGTT


 


951
CAAACTGGAA ACCGCACCCG GCGTGTTTGA ATATTATTTG GGCTTGAACA


 


1001
ATTTTTATAC GGTATGGCAG TACAACCACA GCCGGATGTA TGTAACGgcg


 


1051
gtcaggGACA TTGCCAATTC GCTCGGCGGC CCGGGATTGT Aa






This corresponds to the amino acid sequence <SEQ ID 2814; ORF 922.ng>:










g922.pep




1
MEKRKILPLA ICLAALSACT AMEARTPRAN EAQAPRADEM KKESRPAFDA


 


51
AAVPVSDSGF AANANVRRFV DDEVGKGDFS QAEWQDFFDK AAYKADIVKI


 


101
MHRPSTSRPW YVFRTGNSGR AKFHGARRFY AENRAVIDDV AQKYGVPAEL


 


151
IVAIIGIETN YGKNTGSFRV ADALATLGFD YPRRAGFFQK ELVELLKLAK


 


201
EEGGDVFAFK GSYAGAMGMP QFMPSSYRKW AVDYDGDGHR DIWGNVGDVA


 


251
ASVANYMKQH GWRTGGKMLV SATLAPGADV QAIIGEKTAL TRTVADLKAY


 


301
GIIPGETLAD DEKAVLFKLE TAPGVFEYYL GLNNFYTVWQ YNHSRMYVTA


 


351
VRDIANSLGG PGL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2815>:










m922.seq




1
ATGAAAAAGA GAAAAATACT GCCGCTGGCA ATTTGTTTGG CGGCTTTGTC


 


51
TGCCTGTACG GCGATGGAGG CACGCCCACC CCGGGCAAAT GAAGCCCAAG


 


101
CCCCCCGCGC GGTTGAAATG AAAAAAGAAA GCCGCCCCGC GTTTGACGCG


 


151
GCAGCCGTAT TTGACGCGGC AGCCGTACCG GTATCCGACA GCGGGTTTGC


 


201
CGCCAATGCA AATGTCCGCC GTTTTGTGGA CGATGAAGTC GGGAAAGGGG


 


251
ATTTTTCCCG GGCGGAATGG CAGGATTTTT TTGACAAAGC GGCTTACAAG


 


301
GCGGACATCG TCAAGATTAT GCACCGCCCC TCCACATCGC GTCCGTGGTA


 


351
TGTGTTCCGC ACGGGAAATT CGGGCAAGGC GAAATTTCGC GGCGCGCGCC


 


401
GGTTTTATGC GGAAAACCGC GCGCTTATCG ATGATGTGGC GCAAAAATAC


 


451
GGCGTGCCTG CCGAACTTAT CGTGGCGGTT ATCGGGATTG AAACGAATTA


 


501
CGGCAAAAAT ACGGGCAGTT TCCGTGTGGC GGACGCATTG GCGACCTTAG


 


551
GCTTTGATTA CCCCCGCCGC GCCGGGTTTT TCCAAAAAGA ATTGGTCGAG


 


601
CTTTTAAAGC TGGCAAAAGA AGAAGGCGGC GATGTTTTCG CCTTTAAAGG


 


651
CAGCTATGCG GGCGCAATGG GGATGCCGCA ATTTATGCCT TCGAGCTACC


 


701
GGAAATGGGC GGTGGATTAT GACGGGGACG GACATCGGGA CATATGGGGC


 


751
AACGTCGGCG ATGTCGCGGC ATCGGTTGCC AATTATATGA AGCAGCACGG


 


801
TTGGCGCACG GGCGGGAAAA TGCTGGTGTC TGCAACATTG GCGCCGGGTG


 


851
CGGATGTTCA GGCAATCATT GGCGAAAAAA CCGCCCTGAC GCGGACGGTG


 


901
GCGGATTTGA AGGCGTACGG CATCATCCCC GGCGAAGAGC TTGCAGATGA


 


951
TGAAAAGGCG GTTTTGTTCA AACTGGAAAC CGCACCGGGC GTGTTTGAAT


 


1001
ATTATTTGGG CTTGAACAAT TTTTATACGG TATGGCAGTA CAACCACAGC


 


1051
CGGATGTATG TAACGGCGGT CAGGGACATT GCCAATTCGC TTGGCGGCCC


 


1101
GGGATTGTAA






This corresponds to the amino acid sequence <SEQ ID 2816; ORF 922>:










m922.pep




1
MKKRKILPLA ICLAALSACT AMEARPPRAN EAQAPRAVEM KKESRPAFDA


 


51
AAVFDAAAVP VSDSGFAANA NVRRFVDDEV GKGDFSRAEW QDFFDKAAYK


 


101
ADIVKIMHRP STSRPWYVFR TGNSGKAKFR GARRFYAENR ALIDDVAQKY


 


151
GVPAELIVAV IGIETNYGKN TGSFRVADAL ATLGFDYPRR AGFFQKELVE


 


201
LLKLAKEEGG DVFAFKGSYA GAMGMPQFMP SSYRKWAVDY DGDGHRDIWG


 


251
NVGDVAASVA NYMKQHGWRT GGKMLVSATL APGADVQAII GEKTALTRTV


 


301
ADLKAYGIIP GEELADDEKA VLFKLETAPG VFEYYLGLNN FYTVWQYNHS


 


351
RMYVTAVRDI ANSLGGPGL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 922 shows 95.9% identity over a 369 aa overlap with a predicted ORF (ORF 922.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2817>:










a922.seq




1
ATGAAAAACA GAAAAATACT GCCGCTGGCA ATTTGTTTGG CGGCTTTGTC


 


51
TGCCTGTACG GCGATGGAGG CACGCCCGCC CCGGGCAAAT GAAGCCCAAG


 


101
CCCCCCGCGC GGATGAAATG AAAAAAGAAA GCCGCCCCGC GTTTGACGCG


 


151
GCAGCCGTAT TTGACGCGGC AGCCGTACCG GTATCCGACA GCGGGTTTGC


 


201
CGCCAATGCA AATGTCCGCC GTTTTGTGGA CGATGAAGTC GGGAAAGGGG


 


251
ATTTTTCCCG GGCGGAATGG CAGGATTTTT TTGACAAAGC GGCTTACAAG


 


301
GCGGACATCG TCAAGATTAT GCACCGCCCC TCCACATCGC GTCCGTGGTA


 


351
TGTGTTCCGC ACGGGAAATT CGGGCAAGGC GAAATTTCGC GGCGCGCGCC


 


401
GGTTTTATGC GGAAAACCGC GCGCTTATCG ATGATGTGGC GCAAAAATAC


 


451
GGCGTGCCTG CCGAACTTAT CGTGGCGGTT ATCGGGATTG AAACGAATTA


 


501
CGGCAAAAAT ACGGGCAGTT TCCGTGTGGC GGACGCATTG GCGACCTTAG


 


551
GCTTTGATTA CCCCCGCCGC GCCGGGTTTT TCCAAAAAGA ATTGGTCGAG


 


601
CTTTTAAAGC TGGCAAAAGA AGAAGGCGGC GATGTTTTCG CCTTTAAAGG


 


651
CAGCTATGCG GGCGCAATGG GGATGCCGCA ATTTATGCCT TCGAGCTACC


 


701
GGAAATGGGC GGTGGATTAT GACGGGGACG GACATCGGGA CATATGGGGC


 


751
AATGTTGGCG ATGTCGCGGC ATCGATTGCC AATTATATGA AGCAGCACGG


 


801
TTGGCGCACG GGCGGGAAAA TACTGGTGTC TGCAACATTG GCGCCGGGTG


 


851
CGGATGTTCA GGCAATCATT GGCGAAAAAA CCGCCCTGAC GCGGACGGTG


 


901
GCGGATTTGA AGGCGTACGG CATCATCCCC GGCGAAGAGC TTGCCGATGA


 


951
TGAAAAGGCG GTTTTGTTCA AACTGGAAAC CGCACCCGGC GTGTTTGAAT


 


1001
ATTATTTGGG CTTGAACAAT TTTTATACGG TATGGCAGTA CAATCACAGT


 


1051
CGGATGTATG TAACGGCGGT CAGGGACATT GCCAATTCGC TTGGCGGCCC


 


1101
GGGATTGTAA






This corresponds to the amino acid sequence <SEQ ID 2818; ORF 922.a>:










a922.pep




1
MKNRKILPLA ICLAALSACT AMEARPPRAN EAQAPRADEM KKESRPAFDA


 


51
AAVFDAAAVP VSDSGFAANA NVRRFVDDEV GKGDFSRAEW QDFFDKAAYK


 


101
ADIVKIMHRP STSRPWYVFR TGNSGKAKFR GARRFYAENR ALIDDVAQKY


 


151
GVPAELIVAV IGIETNYGKN TGSFRVADAL ATLGFDYPRR AGFFQKELVE


 


201
LLKLAKEEGG DVFAFKGSYA GAMGMPQFMP SSYRKWAVDY DGDGHRDIWG


 


251
NVGDVAASIA NYMKQHGWRT GGKILVSATL APGADVQAII GEKTALTRTV


 


301
ADLKAYGIIP GEELADDEKA VLFKLETAPG VFEYYLGLNN FYTVWQYNHS


 


351
RMYVTAVRDI ANSLGGPGL*






m922/a922 98.9% identity in 369 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2819>:










g923.seq




1
ATGAAGCGGC AGGCTTTCTT CAAACCGATG GCGTGTGCGG CATTTCTGTC


 


51
CGCCGTTTCG CTGCGCCTCC CCGTATTGGG CGCGTGTTAC GCAATATTGT


 


101
CCCTCTATGC GTTTGCACTT TACGGCATCG ACAAACGGCG TGCCGTGCGG


 


151
GGAAAACGCC GCATTCCCGA ACACCGCCTG CTCCTGCCTG CCTTGTTCGG


 


201
CGGTTGGACG GGCGCATACT TGGGTAGTAG GATGTTCAGG CATAAAACGG


 


251
CGAAAAAGCG TTTTGTTGTG CTGTTCCGTC TGACTGTTTC GGGCAATGTC


 


301
CTGGCGACCT GCATCCTGAT TGATTATTTC GTTCCGCCCG AACTTTTTGT


 


351
AAAACTCGGG CAACATCTCT GA






This corresponds to the amino acid sequence <SEQ ID 2820; ORF 923.ng>:










g923.pep




1
MKRQAFFKPM ACAAFLSAVS LRLPVLGACY AILSLYAFAL YGIDKRRAVR


 


51
GKRRIPEHRL LLPALFGGWT GAYLGSRMFR HKTAKKRFVV LFRLTVSGNV


 


101
LATCILIDYF VPPELFVKLG QHL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2821>:










m923.seq




1
ATGAAGCGGC AGGCTTTCTT CAAACTGATG GCGTGTGCGG CATTTCTGTC


 


51
TGCCGTTTCG CTGCGCCTCC CCGTATTGGG CGCGTGTTAC GCAATATTGT


 


101
CCCTCTATGC GTTTGCACTT TACGGCATCG ACAAACGGTG CGCCATACGG


 


151
GGGCAACGCC GCATTCCCGA ACACCGCCTG CTGCTGCCTG CATTGCTCGG


 


201
CGGCTGGGTG GGCGCGTATT TCGGCAGCAT GACATTCAAA CATAAGACAG


 


251
CGAAAAAGCG TTTTGTTGTG CTGTTCCGTC TGACTGTTTC AGGTAATGTC


 


301
TTGGCGACCC TCATCCTGAT TTATAGTGGA TTAAATTTAA ACCAGTACGG


 


351
CGTTGCCTCG CCTTGCCGTA CTATTTGTAC TGTCTGCGGC TTCGTCGCCT


 


401
TGTCCTGATT TTTGTTAATC CACTATAT.T ATTTTGTCCC GCCTGAATTT


 


451
TTCGTAAAAC TCGGGCAGAA TACCTGA






This corresponds to the amino acid sequence <SEQ ID 2822; ORF 923>:










m923.pep




1
MKRQAFFKLM ACAAFLSAVS LRLPVLGACY AILSLYAFAL YGIDKRCAIR


 


51
GQRRIPEHRL LLPALLGGWV GAYFGSMTFK HKTAKKRFVV LFRLTVSGNV


 


101
LATLILIYSG LNLNQYGVAS PCRTICTVCG FVALS*FLLI HYXYFVPPEF


 


151
FVKLGQNT*






Computer analysis or this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 923 shows 68.8% identity over a 157 aa overlap with a predicted ORF (ORF 923.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2823>:










a923.seq




1
ATGAAGCGGC AGGCTTTCTT CAAACTGATG GCGTGTGCGG CATTTCTGTC


 


51
TGCCGTTTCG CTGCGCCTCC CCGTATTGGG CGCGTGTTAC GCAATATTGT


 


101
CCCTCTATGC GTTTGCACTT TACGGCATCG ACAAACGGCG TGCCGTGCGG


 


151
GGAAAACGCC GCATTCCCGA ACACCGCCTG CTGCTGCCTG CCTTGTTCGG


 


201
CGGTTGGGCG GGCGCATACT TGGGCAGCAG GATATTCAGG CATAAAACGG


 


251
CGAAAAAGCG TTTTGTTGTG CTGTTCCGTC TGACTGTTTC GGGCAATGTC


 


301
CTGGCGACCC TCATCCTGAT TTATAGTGGA TTAAATTTAA ACCAGTACGG


 


351
CGTTGCCTCG CCTTA.GCTC AAAGAGAACG ATTCTCTAAG GTGCTGAAGC


 


401
ACCAAGTGAA TCGGTTCCGT ACTATTTGTA CTGTCTGCGG CTTCGTCGCC


 


451
TTGTCCTGAT TTTTGTTAAT CCACTAT.AT TATTTTGTCC CGCCTGAATT


 


501
TTTCGTAAAA CTCGGGCAGA ATACCTGA






This corresponds to the amino acid sequence <SEQ ID 2824; ORF 923.a>:










a923.pep




1
MKRQAFFKLM ACAAFLSAVS LRLPVLGACY AILSLYAFAL YGIDKRRAVR


 


51
GKRRIPEHRL LLPALFGGWA GAYLGSRIFR HKTAKKRFVV LFRLTVSGNV


 


101
LATLILIYSG LNLNQYGVAS PXAQRERFSK VLKHQVNRFR TICTVCGFVA


 


151
LS*FLLIHYX YFVPPEFFVK LGQNT*






m923/a923 84.6% identity in 175 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2825>:










g925.seq




1
ATGAAACAAA TGCTTTTGGC cgtcggcgtg ggcGCGGTGT TGGCGGGCTG


 


51
CGGCAaggat gcCGGCGGtt acgagggtTA TTGGCGCGAA AAGTCGGACA


 


101
AAAAagaggG CGTGATTGCC GTCAAAAAAA AAGGCAATTA CTTCCTTAAT


 


151
AAAATCAACG TGTTTACAGG CAAGGAGGAG TCTTTGCTTT TGTCTGAAAA


 


201
AGACGGCGCG CTTTCGATAA ACACGGGGAT AGGGGAAATC CCGATCAAAC


 


251
TTTCCGACGA CGGGAAAGAG CTGTATGTCG AACGCAGGCG GTATGTGAAA


 


301
ACCGATGCGG CGATGAAGGA CAAAATCATC GCCCACCAGA AAAAGTGCGG


 


351
ACAAACGGCA CAGGCATACC TCGACGCGCG AAATGCGTTG CCGTCAAACC


 


401
AAACGTATCA GCAGCGTCAG GCGGCGATCG AGCAATTGAA ACGGCGGTTT


 


451
GAAGCCGAGT TTGACGAATT GGAAAAAGAA ATCAAATGCA ACGGCAAACC


 


501
GACATTGTTG TTTTAG






This corresponds to the amino acid sequence <SEQ ID 2826; ORF 925.ng>:










g925.pep




1
MKQMLLAVGV GAVLAGCGKD AGGYEGYWRE KSDKKEGVIA VKKKGNYFLN


 


51
KINVFTGKEE SLLLSEKDGA LSINTGIGEI PIKLSDDGKE LYVERRRYVK


 


101
TDAAMKDKII AHQKKCGQTA QAYLDARNAL PSNQTYQQRQ AAIEQLKRRF


 


151
EAEFDELEKE IKCNGKPTLL F*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2827>:









m925.seq (partial)










1
ATGAAACAAA TGCTTTTAGC CGTCGGCGTG GTGGCGGTGT TGGCGGGCTG



 


51
CGGCAAGGAT GCCGGCGGTT ACGAGGGTTA TTGGCGCGAA AAGTCGGACA


 


101
AAAAAGAGGG TATGATTGCC GTCAAAAAAG AAAAAGGCAA TTACTTCCTT



.......






This corresponds to the amino acid sequence <SEQ ID 2828; ORF 925>:









m925.pep (partial)










1
MKQMLLAVGV VAVLAGCGKD AGGYEGYWRE KSDKKEGMIA VKKEKGNYFL..







Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 925 shows 94.0% identity over a 50 aa overlap with a predicted ORF (ORF 925.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2829>:










g925-1.seq




1
ATGAAACAAA TGCTTTTGGC CGTCGGCGTG GCGGCGGTGT TGGCGGGCTG


 


51
CGGCAAGGAT GCCGGCGGTT ACGAGGGTTA TTGGCGCGAA AAGTCGGACA


 


101
AAAAAGAGGG CGTGATTGCC GTCAAAAAAA AAGGCAATTA CTTCCTTAAT


 


151
AAAATCAACG TGTTTACAGG CAAGGAGGAG TCTTTGCTTT TGTCTGAAAA


 


201
AGACGGCGCG CTTTCGATAA ACACGGGGAT AGGGGAAATC CCGATCAAAC


 


251
TTTCCGACGA CGGGAAAGAG CTGTATGTCG AACGCAGGCG GTATGTGAAA


 


301
ACCGATGCGG CGATGAAGGA CAAAATCATC GCCCACCAGA AAAAGTGCGG


 


351
ACAAACGGCA CAGGCATACC TCGACGCGCG AAATGCGTTG CCGTCAAACC


 


401
AAACGTATCA GCAGCGTCAG GCGGCGATCG AGCAATTGAA ACGGCGGTTT


 


451
GAAGCCGAGT TTGACGAATT GGAAAAAGAA ATCAAATGCA ACGGCAAACC


 


501
GACATTGTTG TTTTAG






This corresponds to the amino acid sequence <SEQ ID 2830; ORF 925-1.ng>:










g925-1.pep




1
MKQMLLAVGV AAVLAGCGKD AGGYEGYWRE KSDKKEGVIA VKKKGNYFLN


 


51
KINVFTGKEE SLLLSEKDGA LSINTGIGEI PIKLSDDGKE LYVERRRYVK


 


101
TDAAMKDKII AHQKKCGQTA QAYLDARNAL PSNQTYQQRQ AAIEQLKRRF


 


151
EAEFDELEKE IKCNGKPTLL F*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2831>:










m925-1.seq




1
ATGAAACAAA TGCTTTTAGC CGTCGGCGTG GTGGCGGTGT TGGCGGGCTG


 


51
CGGCAAGGAT GCCGGCGGTT ACGAGGGTTA TTGGCGCGAA AAGTCGGACA


 


101
AAAAAGAGGG TATGATTGCC GTCAAAAAAG AAAAAGGCAA TTACTTCCTT


 


151
AATAAAATCC ACGTGGTTAC AGGCAAGGAA GAGTCCTTGC TTTTGTCTGA


 


201
AAAAGACGGC GCGCTTTCGA TAAACACAGG GATAGGGGAA ATCCCGATCA


 


251
AACTTTCCGA CGACGGGAAA GAGCTGTATG TCGAACGTAG GCAGTATGTC


 


301
AAAACCGATG CGGCGATGAA GGACAAAATC ATCGCCCATC AGAAAAAGTG


 


351
CGGACAAACA GCACAGGCAT ACCGCGACGC GCGAAATGCG TTGCCGTCAA


 


401
ACCAGACGTA TCAGCAGCAT CTGGCGGCGA TCGAGCAATT GAAACGGCGG


 


451
TTTGAAGCCG AGTTTGACGA ATTGGAAAAA GAAATCAAAT GCAACGGCAG


 


501
AAGCCCGGCA TTGTTGCTTT AG






This corresponds to the amino acid sequence <SEQ ID 2832; ORF 925-1>:










m925-1.pep..




1
MKQMLLAVGV VAVLAGCGKD AGGYEGYWRE KSDKKEGMIA VKKEKGNYFL


 


51
NKIHVVTGKE ESLLLSEKDG ALSINTGIGE IPIKLSDDGK ELYVERRQYV


 


101
KTDAAMKDKI IAHQKKCGQT AQAYRDARNA LPSNQTYQQH LAAIEQLKRR


 


151
FEAEFDELEK EIKCNGRSPA LLL*






m925/g925 92.5% identity in 173 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2833>:










a925-1.seq




1
AATAAAATCA ACGTGTTTAC AGGTAAGGAA GAATCTATGC TTTTGTCTGA


 


51
AAAAGACGGC GCGCTTTCGA TAAACACGGG GATAGGGGAA ATCCCGATCA


 


101
AACTTTCCGA CGACGGGAAA GAGCTGTATG TCGAACGCAG GCAGTATGTC


 


151
AAAACCGATG CGGCGATGAA GGACAAAATC ATCGCCCATC AGAAAAAGTG


 


201
CGGACAAACG GCACAGGCAT ATCTCGACGC GCGAAATGCG TTGCCGTCAA


 


251
ACCAGACGTA TCAGCAGCAT CAGGCGGCGA TCGAGCAGTT GAAACGGCGG


 


301
TTTGAAGCCG AGTTTGACGA ATTGGAAAAA GAAATCAAAT GCAACGGCAA


 


351
ACCGACATTG TTGTTTTAG






This corresponds to the amino acid sequence <SEQ ID 2834; ORF 925-1.a>:










a925-1.pep




1
NKINVFTGKE ESMLLSEKDG ALSINTGIGE IPIKLSDDGK ELYVERRQYV


 


51
KTDAAMKDKI IAHQKKCGQT AQAYLDARNA LPSNQTYQQH QAAIEQLKRR


 


101
FEAEFDELEK EIKCNGKPTL LF*






a925-1/m925-1 92.7% identity in 123 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2835>:









g926.seq (partial)










1
ATGAAACACA CCGTATCCGC ATCGGTCATC CTGCTTTTGA CCGCTTGCGC



 


51
GCAATTACCT CAAAATAACG AAAACCTGTG GCAGCCGTCC GAACACATCA


 


101
GCAGTTTTGC AGCGGAAGGG CGGTTGGCAG TCAAAGCGGA AGGGAAAGGT


 


151
TCGTATGCAA ATTTCGATTG GACATACCAA CCGCCCGTGG AAACCATCAA


 


201
TATCAACACC CCTTTGGGCA GTACGCTCGG ACAGTTGTGT CAAGacAGGG


 


251
ACGGCGCATT GGCAGTGGAC GGCAAAGGAA ATGTCTATCA GGCAGAGGGT


 


301
ACGgaagact tGAGCAGGCA GCTGGTCGGT TTCAAACTGC CAATCCAATA


 


351
TCTGCATATC TGGGCGGAAG GCAGGCGTGT GGCGGGCGCG CCTtaccGCA


 


401
TCCGTTCAGA CGGCATATTG GAACAATAcg GttggACAAT cgggCagaac


 


451
tgcCGACAGT GGGGGGCaag tccgaacgtt gcaactGAa...






This corresponds to the amino acid sequence <SEQ ID 2836; ORF 926.ng>:









g926.pep (partial)










1
MKHTVSASVI LLLTACAQLP QNNENLWQPS EHISSFAAEG RLAVKAEGKG



 


51
SYANFDWTYQ PPVETININT PLGSTLGQLC QDRDGALAVD GKGNVYQAEG


 


101
TEDLSRQLVG FKLPIQYLHI WAEGRRVAGA PYRIRSDGIL EQYGWTIGQN


 


151
CRQWGASPNV ATE...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2837>:










m926.seq




1
ATGAAACACA CCGTATCCGC ATCGGTCATC CTGCTTTTGA CCGCTTGCGC


 


51
GCAATTACCT CAAAATAACG AAAACCTGTG GCAGCCGTCC GAACACATCA


 


101
GCAGTTTTGC AGCAGAAGGG CGGTTGGCAG TGAAAGCGGA AGGGAAAGGT


 


151
TCGTATGCAA ATTTCGATTG GACATACCAA CCGCCCGTGG AAACCATCAA


 


201
TATCAATACC CCTTTGGGCA GTACGCTCGG GCAGTTGTGT CAAGACAGGG


 


251
ACGGCGCATT GGCAGTGGAC GGCAAAGGAA ATGTCTATCA GGCGGAAAGT


 


301
GCGGAAGAAT TGAGCAGGCA GCTGGTCGGT TTCAAACTGC CAATCCAATA


 


351
TCTGCATATC TGGGCAGATG GCAGGCGTGT GGCGGGCGCG CCTTACCGCA


 


401
TCCTGCCGGA CGGCATATTG GAACAATACG GTTGGACTGT CGGCAGAACC


 


451
GCCGACAGTG GGGGGCAAGT CCGAACGTTG CAACTGAATA ACGGAAATTT


 


501
GAACATCAGG CTGGTTTTCA CCGAAATCGG TATGCCGTCT GAAACCGAAA


 


551
CCCCGGAACG CTGTGCGGCG CGCACGAGAT AA






This corresponds to the amino acid sequence <SEQ ID 2838; ORF 926>:










m926.pep




1
MKHTVSASVI LLLTACAQLP QNNENLWQPS EHISSFAAEG RLAVKAEGKG


 


51
SYANFDWTYQ PPVETININT PLGSTLGQLC QDRDGALAVD GKGNVYQAES


 


101
AEELSRQLVG FKLPIQYLHI WADGRRVAGA PYRILPDGIL EQYGWTVGRT


 


151
ADSGGQVRTL QLNNGNLNIR LVFTEIGMPS ETETPERCAA RTR*






g926/m926 91.6% identity in 155 aa overlap














a926.seq




1
ATGAAACACA CTGTATCCGC ATCGGTCATC CTGCTTTTGA CCGCTTGCGC


 


51
GCAATTACCT CAAAATAACG AAAACCTGTG GCAGCCGTCC GAACACACCC


 


101
GCAGTTTCAC GGCGGAAGGG CGGTTGGCAG TGAAAGCGGA AGGGAAAGGT


 


151
TCGTATGCAA ATTTCGATTG GACATACCAA CCGCCCGTGG AAACCATCAA


 


201
TATCAACACC CCTTTGGGCA GTACGCTCGG GCAGTTGTGT CAAGACAGGG


 


251
ACGGCGCATT GGCAGTGGAC GGCAAAGGAA ATGTCTATCA GGCGGAAAGT


 


301
GCGGAAGAAT TGAGCAGGCA GCTGGTCGGT TTCAAACTGC CAATCCAATA


 


351
TCTGCATATC TGGGCAGATG GCAGGCCTGT GGCGGGCGCG CCTTACCGCA


 


401
TCCTGCCGGA CGGCATATTG GAACAATACG GTTGGACTGT CGGCAGAACC


 


451
GCCGACAGTG GGGGGCAAGT CCGAACGTTG CAACTGAATA ACGGAAATTT


 


501
GAACATCAGG CTGGTTTTCA CCGAGATTGG TATGCCGTCT GAAACCGAAA


 


551
CCCAAGAACA ATGCGCGGCA CGCATACAGT AA


 


a926.pep


1
MKHTVSASVI LLLTACAQLP QNNENLWQPS EHTRSFTAEG RLAVKAEGKG


 


51
SYANFDWTYQ PPVETININT PLGSTLGQLC QDRDGALAVD GKGNVYQAES


 


101
AEELSRQLVG FKLPIQYLHI WADGRPVAGA PYRILPDGIL EQYGWTVGRT


 


151
ADSGGQVRTL QLNNGNLNIR LVFTEIGMPS ETETQEQCAA RIQ*






m926/a926 96.9% identity in 191 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2839>:










g927.seq




1
atgaaaacct acGCAcAggC ACTCTATacc GCAGCCCTGC TCACCGCCTG


 


51
CAGCCCcgca GCcgatTcaa accaTCCGTC CGGAcAaAAT GCCCCGGCCA


 


101
ATACCGAATC cgacGgaaAA AACATtaccC TGctcaatgc cTcgtacgat


 


151
gtGACACGGT ATTTttacaa agaatacgac cacTtgtttg tcggaaCATA


 


201
CCAATCCGAA CACCCCGGCA CATCCGTCAG CATCCAACAA TCCCACGGCG


 


251
GCTTCAGCAA ACAGGCATTA TCCGTAGCCA ACGGCCTTCA AGCCGATGTC


 


301
GTAACCATGA ACCAATCTTC CGACATCGAC CTGCTCGAAA AAAA.GGACT


 


351
GGTAGAAAAA GGCTGGCAAC AAGCCCTCCC CGATCACGCC GCACCCTACA


 


401
CCAGCACTAT GGTTTTCCTT GTCCGAAAAA ACAACCCcaa ACAGAtccgC


 


451
GATTGGAACG ACCTTGCCAA AGACGGCGTT AACATCGTCA TCGCCAAGAC


 


501
CTCGGGCAAC GGACGCTACG CCTTCCTCGG CGCATACGGT TACGGTCTGA


 


551
AAGCCAACAA CGGcaaCGAG CAGGAAGCCC AAAAACTCGT CGCATCCATC


 


601
CTCAAAAACA CACCCGTTTT TGAAAACGGC GGACGCGc.C CGCCGCCACC


 


651
ACCTTCACAC AACGCAACAT CGGCGACGTA CTCATCACTT TTGAAAACga


 


701
agCcaactac gtCAGCAAAA AACTGA






This corresponds to the amino acid sequence <SEQ ID 2840; ORF 927.ng>:










g927.pep




1
MKTYAQALYT AALLTACSPA ADSNHPSGQN APANTESDGK NITLLNASYD


 


51
VTRYFYKEYD HLFVGTYQSE HPGTSVSIQQ SHGGFSKQAL SVANGLQADV


 


101
VTMNQSSDID LLEKXGLVEK GWQQALPDHA APYTSTMVFL VRKNNPKQIR


 


151
DWNDLAKDGV NIVIAKTSGN GRYAFLGAYG YGLKANNGNE QEAQKLVASI


 


201
LKNTPVFENG GRXPPPPPSH NATSATYSSL LKTKPTTSAK N*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2841>:










m927.seq




1
ATGAAAACCT ACGCACCGGC ACTCTATACC GCAGCCCTGC TCACCGCCTG


 


51
CAGCCCCGCA GCCGATTCAA ACCATCCGTC CGGACAAAAT GCCCCGGCCA


 


101
ATACCGAATC CGACGGAAAA AACATTACCC TGCTCAACGC CTCATACGAT


 


151
GTGGCACGGG ATTTTTACAA AGAATACAAC CCCTTATTTA TCAAAACATA


 


201
CCAATCCGAA CACCCCGGCA CATCCGTCAG CATCCAACAG TCCCACGGCG


 


251
GCTCCAGCAA ACAGGCATTA TCCGTAGCCA ACGGCCTTCA AGCCGATGTC


 


301
GTAACCATGA ACCAATCCTC CGACATCGAC CTGCTCGAAA AAAAAGGACT


 


351
GGTAGAAAAA GGCTGGCAAC AAGCCCTCCC CGACCACGCC GCGCCCTACA


 


401
CCAGCACTAT GGTTTTCCTT GTCCGAAAAA ACAACCCCAA ACAGATCCGC


 


451
GATTGGAACG ACCTTGCCAA AGACGGCGTT AACATCGTCA TCGCCAATCC


 


501
CAAAACCTCG GGCAACGGAC GCTACGCCTT CCTCGGCGCA TACGGTTACG


 


551
GTCTGAAAAC CACCAACGGC AACGAACAGG AAGCCCAAAA ACTCGTCGCA


 


601
TCCATCCTCA AAAACACCCC CGTTTTTGAA AACGGCGGAC GCkCgCCACC


 


651
ACCACCTTCA CACAACGCAA CATCGGCGAC GTACTCATCA CTTTTGAAAA


 


701
CGAAGCCAAC TACGTCAGCr AAAAACtGA






This corresponds to the amino acid sequence <SEQ ID 2842; ORF 927>:










m927.pep




1
MKTYAPALYT AALLTACSPA ADSNHPSGQN APANTESDGK NITLLNASYD


 


51
VARDFYKEYN PLFIKTYQSE HPGTSVSIQQ SHGGSSKQAL SVANGLQADV


 


101
VTMNQSSDID LLEKKGLVEK GWQQALPDHA APYTSTMVFL VRKNNPKQIR


 


151
DWNDLAKDGV NIVIANPKTS GNGRYAFLGA YGYGLKTTNG NEQEAQKLVA


 


201
SILKNTPVFE NGGRXPPPPS HNATSATYSS LLKTKPTTSA KN*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 927 shows 94.2% identity over a 243 aa overlap with a predicted ORF (ORF 927.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2843>:










a927.seq




1
ATGAAAACCT ACGCACCGGC ACTCTATACC GCAGCCCTGC TCAGCGCCTG


 


51
CAGCCCCGCA GCCGATTCAA ACCATCCGTC CGGACAAAAT GCCCCGGCCA


 


101
ATACCGAATC CGACGGAAAA AACATTACCC TGCTCAACGC CTCATACGAT


 


151
GTGGCACGGG ATTTTTACAA AGAATACAAC CCCTTATTTA TCAAAACATA


 


201
CCAATCCGAA CACCCCGGCA CATCCGTCAG CATCCAACAG TCCCACGGCG


 


251
GCTCCAGCAA ACAGGCATTA TCCGTAGCCA ACGGCCTTCA AGCCGATGTC


 


301
GTAACCATGA ACCAATCCTC CGACATCGAC CTGCTCGAAA AAAAAGGACT


 


351
GGTAGAAAAA GGCTGGCAAC AAGCCCTCCC CGACCACGCC GCGCCCTACA


 


401
CCAGCACTAT GGTTTTCCTT GTCCGAAAAA ACAACCCCAA ACAGATCCGC


 


451
GATTGGAACG ACCTTGCCAA AGACGGCGTT AACATCGTCA TCGCCAATCC


 


501
CAAAACCTCG GGCAACGGAC GCTACGCCTT CCTCGGCGCA TACGGTTACG


 


551
GTCTGAAAAC CACCAACGGC AACGAACAGG AAGCCCAAAA ACTCGTCGCA


 


601
TCCATCCTCA AAAACACCCC CGTTTTTGAA AACGGCGGAC GCGCGCCACC


 


651
ACCACCTTCA CACAACGCAA CATCGGCGAC GTACTCATCA CTTTTGAAAA


 


701
CGAAGCCAAC TACGTCAGCA AAAAACTGA






This corresponds to the amino acid sequence <SEQ ID 2844; ORF 927.a>:










a927.pep




1
MKTYAPALYT AALLSACSPA ADSNHPSGQN APANTESDGK NITLLNASYD


 


51
VARDFYKEYN PLFIKTYQSE HPGTSVSIQQ SHGGSSKQAL SVANGLQADV


 


101
VTMNQSSDID LLEKKGLVEK GWQQALPDHA APYTSTMVFL VRKNNPKQIR


 


151
DWNDLAKDGV NIVIANPKTS GNGRYAFLGA YGYGLKTTNG NEQEAQKLVA


 


201
SILKNTPVFE NGGRAPPPPS HNATSATYSS LLKTKPTTSA KN*






m927/a927 99.2% identity in 242 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2845>:










g929.seq




1
ATGAAATTGG GTTTCAAACC GATACCCCTC GCCATTGCCG CAGTATTGTG


 


51
CGCCCTGGTT TTGGCACTGC CCGTACccga CGGGGTCAAG CCTCAGGCTT


 


101
GGACGCTGCT GGCTATGTTT GTCGGTGTGA TTGCCGCCAT TATCGGCAAG


 


151
GTTATGCCGT TGGGCGCGCT GTCGATTATT GCCGTCGGGT TGGTCGCAGT


 


201
AACCGGCGTA ACCGCCGACA AACCGGGCGC GGCGATGAGC GATGCGTTGA


 


251
GTGCGTTCGC CAATCCGTTG ATTTGGCTGA TTGCCATCGC AGTTATGATT


 


301
TCGCGCGGTT TGCTCAAAAC AGGGCTGGGG ATGCGTATCG GATATTTGTT


 


351
TATCGCCGTT TTTGGAAGAA AAAcgctggG CATCGGTTAC AGTCTCGCTC


 


401
TTTCCGAACT GCTGCTGGCT CCCGTTACCC CTTCCAATAC CGCGCGCGGC


 


451
GGCGGCATTA TACATCcgaT TATGCagtcg attgCcggCA GttacggctC


 


501
caatCCCGCA AAAGGCACag aaggcaagat gggtaAATAT TtggcTTtgg


 


551
tcaattaTCA TTCcaaTCCC atttcgtcgg ctAtggctat taCTGcaact


 


601
gCCCCcaaCC CTTTAATcgt caacttgatt gccGaaaaTt taggcagtag


 


651
tttccgtCTT TCttgggggg cgTGGGcgtg ggcaaTGGCT Gttcccggcg


 


701
ttatcgcctt TTtcgTTATG CCTTTGATTT TATATTTTTT GTATCCGCCT


 


751
GAAATTAAAG AAACGCCCAA TGCTGttcAA TTTGCCAAAG ACCGTCTGAG


 


801
CGAGATGGGT AAAATGtcgg CAGACGAAAT CATTATGGCG GTCATTTTCG


 


851
GTATCTTGCT GCTGTTGTGG GCAGATGTTC CCGCCCTTAT TACCGGCAAT


 


901
CACGCTTTTA GTATCAacgc caccGCCACC GCATTTATCG GATTAAGCCT


 


951
GCTTTTGCTT TCCGGTGTAT TGACTTGGGA CGATGTTTTG AAAGAAAAAA


 


1001
GCGCGTGGGA TACGATTATT TGGTTTGGCG CATTGATTAT GATGGCCGCA


 


1051
TTTTTaAATA AActcggact gattaaatGG TTCTCCGGAG TGTTGGCGGA


 


1101
AagtgtcggC GGTTTGGGCG TTAGCGGCAC GGCTGCGGGC GTAATCCTCG


 


1151
TGCTTGCtta TATGTATGCG CATTATATGT TTGCCAGTAC TACTGCACAT


 


1201
ATTACCGCTA TGTTCGGCGC ATTTCTCGCT GCTGCCGTTT CACTGAATGC


 


1251
CCCGGCGATG CCGACTGCGC TGATGATGGC GGCCGCATCC AACATTATGA


 


1301
TGACCCTCAC TCATTATGCG ACCGGTACTT CACCTGTGAT TTTCGGCTCG


 


1351
GGCTACACCA CAATGGGAGA ATGGTGGAAG GCGGGTTTTA TCATGAGCGT


 


1401
AGTCAATTTT CTGATTTTTT CCGTTATCGG CAGCATTTGG TGGAAAGTTC


 


1451
TGGGATATTG GTAA






This corresponds to the amino acid sequence <SEQ ID 2846; ORF 929.ng>:










g929.pep




1
MKLGFKPIPL AIAAVLCALV LALPVPDGVK PQAWTLLAMF VGVIAAIIGK


 


51
VMPLGALSII AVGLVAVTGV TADKPGAAMS DALSAFANPL IWLIAIAVMI


 


101
SRGLLKTGLG MRIGYLFIAV FGRKTLGIGY SLALSELLLA PVTPSNTARG


 


151
GGIIHPIMQS IAGSYGSNPA KGTEGKMGKY LALVNYHSNP ISSAMAITAT


 


201
APNPLIVNLI AENLGSSFRL SWGAWAWAMA VPGVIAFFVM PLILYFLYPP


 


251
EIKETPNAVQ FAKDRLSEMG KMSADEIIMA VIFGILLLLW ADVPALITGN


 


301
HAFSINATAT AFIGLSLLLL SGVLTWDDVL KEKSAWDTII WFGALIMMAA


 


351
FLNKLGLIKW FSGVLAESVG GLGVSGTAAG VILVLAYMYA HYMFASTTAH


 


401
ITAMFGAFLA AAVSLNAPAM PTALMMAAAS NIMMTLTHYA TGTSPVIFGS


 


451
GYTTMGEWWK AGFIMSVVNF LIFSVIGSIW WKVLGYW*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2847>:










m929.seq




1
ATGAAATTGG GTTTCAAACC GATACCCCTC GCCATTGCCG CAGTATTGTG


 


51
CGCCCTGGTT TTGGCACTGC CCGTACCCGA CGGGGTCAAG CCTCAGGCTT


 


101
GGACGCTGCT GGCCATGTTT GTCGGTGTGA TTGCCGCCAT TATCGGCAAG


 


151
GCCATGCCGT TGGGCGCGCT GTCGATTATT GCCGTCGGGT TGGTCGCAGT


 


201
AACCGGCGTA ACCGCCGACA AACCGGGCGC GGCGATGAGC GATGCGTTGA


 


251
GTGCGTTCGC CAATCCGTTG ATTTGGCTGA TTGCCATCGC AGTTATGATT


 


301
TCGCGCGGTT TGCTCAAAAC AGGGCTGGGG ATGCGTATCG GATATTTGTT


 


351
TATCGCCGTT TTTGGAAGAA AAACGCTGGG CATCGGTTAC AGTCTCGCTC


 


401
TTTCCGAACT GCTGCTGGCT CCCGTTACCC CTTCCAATAC CGCGCGCGGC


 


451
GGCGGCATTA TACATCCGAT TATGCAGTCG ATTGCCGGCA GTTACGGCTC


 


501
CAATCCCGCA AAAGGCACAG AAGGCAAGAT GGGTAAATAT TTGGCTTTGG


 


551
TCAACTATCA TTCCAATCCC ATTTCGTCGG CTATGTTTAT TACTGCAACT


 


601
GCCCCCAACC CTTTAATCGT CAACTTGATT GCCGAAAATT TAGGCAGTAG


 


651
TTTCCGTCTT TCTTGGGGGG CGTGGGCGTG GGCAATGGCT GTTCCCGGCG


 


701
TTATCGCCTT TTTCGTTATG CCTTTGATTT TATATTTwyT GTATCCGCCT


 


751
GAAATTAAAG AAACGCCCAA TGCCGTTCAA TTTGCCAAAG ACCGTCTGAG


 


801
GGAGATGGGT AAAATGTCGG CAGACGAAAT CATTATGGCG GTCATTTTCG


 


851
GTATCTTGCT GCTGTTGTGG GCAGATGTTC CCGCCCTTAT TACCGGCAAT


 


901
CACGCTTTTA GTATCAACGC CACCGCCACC GCATTTATCG GATTAAGCCT


 


951
GCTTTTGCTT TCCGGTGTAT TGACTTGGGA CGATGTTTTG AAAGAAAAAA


 


1001
GCGCGTGGGA TACGATTATT TGGTTTGGCG CATTGATTAT GATGGCCGCA


 


1051
TTTTTAAATA AACTCGGACT GATTAAATGG TTCTCCGGAG TGTTGGCGGA


 


1101
AAGTGTCGGC GGTTTGGGCG TTAGCGGCAC GGCTGCGGGC GTAATCCTCG


 


1151
TGCTTGCTTA TATGTATGCG CATTATATGT TTGCCAGTAC TACTGCACAT


 


1201
ATTACCGCTA TGTTCGGCGC ATTTTTCGCT GCTGCCGTTT CACTGAATGC


 


1251
CCCGGCGATG CCGACCGCGC TGATGATGGC GgCCGCATCC AACATTATGA


 


1301
TGACCCTCAC TCATTATGCG ACCGGTACTT CGCCTGTGAT TTTCGGTTCG


 


1351
GGCTACACCA CAATGGGAGA ATGGTGGAAG GCGGGTTTTA TCATGAGCGT


 


1401
AGTCAATTTT CTGATTTTTT TCGTTATCGG CAGCATTTGG TGGAAAGTTC


 


1451
TGGGGTATTG GTAA






This corresponds to the amino acid sequence <SEQ ID 2848; ORF 929>:










m929.pep




1
MKLGFKPIPL AIAAVLCALV LALPVPDGVK PQAWTLLAMF VGVIAAIIGK


 


51
AMPLGALSII AVGLVAVTGV TADKPGAAMS DALSAFANPL IWLIAIAVMI


 


101
SRGLLKTGLG MRIGYLFIAV FGRKTLGIGY SLALSELLLA PVTPSNTARG


 


151
GGIIHPIMQS IAGSYGSNPA KGTEGKMGKY LALVNYHSNP ISSAMFITAT


 


201
APNPLIVNLI AENLGSSFRL SWGAWAWAMA VPGVIAFFVM PLILYXLYPP


 


251
EIKETPNAVQ FAKDRLREMG KMSADEIIMA VIFGILLLLW ADVPALITGN


 


301
HAFSINATAT AFIGLSLLLL SGVLTWDDVL KEKSAWDTII WFGALIMMAA


 


351
FLNKLGLIKW FSGVLAESVG GLGVSGTAAG VILVLAYMYA HYMFASTTAH


 


401
ITAMFGAFFA AAVSLNAPAM PTALMMAAAS NIMMTLTHYA TGTSPVIFGS


 


451
GYTTMGEWWK AGFIMSVVNF LIFFVIGSIW WKVLGYW*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 929 shows 98.8% identity over a 487 aa overlap with a predicted ORF (ORF 929.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2849>:










a929.seq




1
ATGAAATTGG GTTTCAAACC GATACCCCTC GCCATTGCCG CAGTATTGTG


 


51
CGCCTTGGTT TTGGCACTGC CCGTACCCGA CGGGGTCAAG CCTCAGGCTT


 


101
GGACGCTGCT GGCCATGTTT ATCGGTGTGA TTGCCGCCAT TATCGGCAAG


 


151
GCCATGCCGT TGGGTGCGCT GTCGATTATT GCCGTCGGGT TGGTCGCAGT


 


201
AACCGGCGTA ACCGCCGACA AACCGGGTGC GGCGATGAGC GATGCGTTGA


 


251
GTGCGTTCGC CAATCCGTTG ATTTGGCTGA TTGCCATCGC AGTTATGATT


 


301
TCGCGCGGTT TGCTCAAAAC AGGGCTGGGG ATGCGTATCG GATATTTGTT


 


351
TATCGCCGTT TTTGGAAGAA AAACGCTGGG CATCGGTTAC AGTCTCGCTC


 


401
TTTCCGAACT GCTGCTGGCT CCCGTTACCC CTTCCAATAC CGCGCGCGGC


 


451
GGCGGCATTA TACATCCGAT TATGCAGTCG ATTGCCGGCA GTTACGGCTC


 


501
CAATCCCGCA AAAGGCACAG AAGGCAAGAT GGGTAAATAT TTGGCTTTGG


 


551
TCAACTATCA TTCCAATCCC ATTTCGTCGG CTATGTTTAT TACTGCAACT


 


601
GCCCCCAACC CTTTAATCGT CAACTTGATT GCCGAAAATT TAGGCAGTAG


 


651
TTTCCGTCTT TCTTGGGGGG CGTGGGCGTG GGCAATGGCT GTTCCCGGCG


 


701
TTATCGCCTT TTTCGTTATG CCTTTGATTT TATATTTTTT GTATCCGCCT


 


751
GAAATTAAAG AAACGCCCAA TGCCGTTCAA TTTGCCAAAG ACCGTCTGAG


 


801
GGAGATGGGT AAAATGTCGG CAGACGAAAT CATTATGGCG GTCATTTTCG


 


851
GTATCTTGTT GCTGTTGTGG GCAGATGTTC CCGCCCTTAT TACCGGCAAT


 


901
CACGCTTTTA GTATCAACGC CACCGCCACC GCATTTATCG GATTAAGCCT


 


951
GCTTTTGCTT TCCGGTGTAT TGACTTGGGA CGATGTTTTG AAAGAAAAAA


 


1001
GCGCGTGGGA TACGATTATT TGGTTTGGCG CATTGATTAT GATGGCCGCA


 


1051
TTTTTAAATA AACTCGGACT GATTAAATGG TTCTCCGGAG TGTTGGCGGA


 


1101
AAGTGTCGGC GGTTTGGGCG TTAGCGGCAC GGCTGCGGGC GTAATCCTCG


 


1151
TGCTTGCTTA TATGTATGCG CATTATATGT TTGCCAGTAC TACTGCACAT


 


1201
ATTACCGCTA TGTTCGGCGC ATTTTTCGCT GCTGCCGTTT CACTGAATGC


 


1251
CCCGGCGATG CCGACCGCGC TGATGATGGC GGCCGCATCT AACATTATGA


 


1301
TGACCCTCAC TCATTATGCG ACCGGTACTT CGCCTGTGAT TTTCGGTTCG


 


1351
GGCTACACCA CAATGGGAGA ATGGTGGAAG GCGGGTTTTA TCATGAGCGT


 


1401
AGTCAATTTT CTGATTTTTT TCGTTATCGG CAGCATTTGG TGGAAAGTTC


 


1451
TGGGGTATTG GTAA






This corresponds to the amino acid sequence <SEQ ID 2850; ORF 929.a>.










a929.pep




1
MKLGFKPIPL AIAAVLCALV LALPVPDGVK PQAWTLLAMF IGVIAAIIGK


 


51
AMPLGALSII AVGLVAVTGV TADKPGAAMS DALSAFANPL IWLIAIAVMI


 


101
SRGLLKTGLG MRIGYLFIAV FGRKTLGIGY SLALSELLLA PVTPSNTARG


 


151
GGIIHPIMQS IAGSYGSNPA KGTEGKMGKY LALVNYHSNP ISSAMFITAT


 


201
APNPLIVNLI AENLGSSFRL SWGAWAWAMA VPGVIAFFVM PLILYFLYPP


 


251
EIKETPNAVQ FAKDRLREMG KMSADEIIMA VIFGILLLLW ADVPALITGN


 


301
HAFSINATAT AFIGLSLLLL SGVLTWDDVL KEKSAWDTII WFGALIMMAA


 


351
FLNKLGLIKW FSGVLAESVG GLGVSGTAAG VILVLAYMYA HYMFASTTAH


 


401
ITAMFGAFFA AAVSLNAPAM PTALMMAAAS NIMMTLTHYA TGTSPVIFGS


 


451
GYTTMGEWWK AGFIMSVVNF LIFFVIGSIW WKVLGYW*






m929/a929 99.6% identity in 487 aa overlap





g930.seq not found yet

g930.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2851>:










m930.seq




1
ATGAAACTTC CTTTATCCTA TTTGCCTAAT ATTCGCTTTT TGTCTTGGTG


 


51
CTGCTTATTG GCAGGTATCA TTGCTCCTGC TACTTTGTTG GCCTCCCCCA


 


101
ACCCTGCCGA AATCCGTATG CAGCAAGATA TTCAGCAACG CCAACGCGAA


 


151
GAGCAGTTGC GCCAAACCAT GCAGCCTGAA AGCGATGTGC GTTTGCATCA


 


201
AAAAAACACG GGGGAAACGG TTAATCAGTT GATGGGCGAT GACAGCAGCC


 


251
AACCGTGTTT TGCCATTAAC GAAtGGGTGT TGGAAGGCGA ACACCATGCT


 


301
CGGTTTCAGT TTGCCCTAAA ACGTGCCTTG CGCGAAACGG GTTTTCAGGC


 


351
TGGCAAGTGT CTGCATGCGG GCAACATTAA TCAAATCATG TCCTTAGCAC


 


401
AAAATGCTTT GATCGGCAGG GGATATACCA CGACCCGTAT CTTGGCTGCG


 


451
CCACAGGATT TGAATAgTGG aAGCTTCAAT TAA






This corresponds to the amino acid sequence <SEQ ID 2852; ORF 930>:










m930.pep




1
MKLPLSYLPN IRFLSWCCLL AGIIAPATLL ASPNPAEIRM QQDIQQRQRE


 


51
EQLRQTMQPE SDVRLHQKNT GETVNQLMGD DSSQPCFAIN EWVLEGEHHA


 


101
RFQFALKRAL RETGFQAGKC LHAGNINQIM SLAQNALIGR GYTTTRILAA


 


151
PQDLNSGSFN *






The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2853>:









g930-1.seq (partial)










1
GGCAAGTGTC TGCATGCGGG CGACATTAAT CAAATCATGT CCTTAGCACA



 


51
AAATGCTTTG ATCGGCAGGG GATATACCAC GACCCGTATC TTGGCTGCGC


 


101
CACAGGATTT GAATAGTGGC AAGCTTCAAT TAACCCTGAT GCCGGGCTAT


 


151
CTGCGCTCCA TACGAATCGA TCGGTCCAAC GATGATCAAA CCCATGCAGG


 


201
ACGTATTGCA GCATTCCAAA ACAAATTTCC CACCCGCTCG AACGATCTGT


 


251
TGAATCTGCG TGATTTGGAA CAAGGACTGG AAAATCTCAA ATGTCTCCCG


 


301
ACTGCGGAAG CCGATCTCCA AATCGTTCCC GTAGAGAGAG AACCAAACCA


 


351
AAGTGATGTC GTGGTGCAAT GGCGGTAACG TCTGCTGCCC TACTGTGTGA


 


401
GTGTGGGGAT GGATAATTCG GGTAGTGAGG CGACAGGAAA ATACCAAGGA


 


451
AATATCACTT TCTCTGCCGA CAATCCTTTT GGACTGAGTG ATATGTTCTA


 


501
TGTAAATTAT GGACGTTCAA TTGGCGGTAC GCCCGATGAG GAAAATTTTG


 


551
ACGGCCATCG CAAAGAAGGC GGATCAAACA ATTACGCCGT ACATTATTCA


 


601
GCCCCTTTCG GTAAATGGAC ATGGGCATTC AATCACAATG GCTACCGTTA


 


651
CCATCAGGCG GTTTCCGGAT TATCGGAAGT CTATGACTAT AATGGAAAAA


 


701
GTTACAACAC TGATTTCGGC TTCAACCGCC TGTTGTATCG TGATGCCAAA


 


751
CGCAAAACCT ATCTCAGTGT AAAACTGTGG ACGAGGGAAA CAAAAAGTTA


 


801
CATTGATGAT GCCGAACTGA CTGTACAACG GCGTAAAACC ACAGGTTGGT


 


851
TGGCAGAACT TTCCCACAAA GGATATATCG GTCGCAGTAC GGCAGATTTT


 


901
AAGTTGAAAT ATAAACACGG CACCGGCATG AAAGATGCTC TGCGCGCGCC


 


951
TGAAGAAGCC TTTGGCGAAG GCACGTCACG TATGAAAATT TGGACGGCAT


 


1001
CGGCTGATGT AAATACTCCT TTTCAAATCG GTAAACAGCT ATTTGCCTAT


 


1051
GACACATCCG TTCATGCACA ATGGAACAAA ACCCCGCTAA CATCGCAAGA


 


1101
CAAACTGGCT ATCGGCGGAC ACCACACCGT ACGTGGCTTC GACGGTGAAA


 


1151
TGAGTTTGCC TGCCGAGCGG GGATGGTATT GGCGCAACGA TTTGAGCTGG


 


1201
CAATTTAAAC CAGGCCATCA GCTTTATCTT GGGGCTGATG TAGGACATGT


 


1251
TTCAGGACAA TCCGCCAAAT GGTTATCGGG CCAAACTCTA GCCGGCACAG


 


1301
CAATTGGGAT ACGCGGGCAG ATAAAGCTTG GCGGCAACCT GCATTACGAT


 


1351
ATATTTACCG GCCGTGCATT GAAAAAGCCC GAATATTTTC AGACGAAGAA


 


1401
ATGGGTAACG GGGTTTCAGG TGGGTTATTC GTTTTGA






This corresponds to the amino acid sequence <SEQ ID 2854; ORF 930-1.ng>:









g930-1.pep (partial)










1
GKCLHAGDIN QIMSLAQNAL IGRGYTTTRI LAAPQDLNSG KLQLTLMPGY



 


51
LRSIRIDRSN DDQTHAGRIA AFQNKFPTRS NDLLNLRDLE QGLENLKCLP


 


101
TAEADLQIVP VEREPNQSDV VVQWR*RLLP YCVSVGMDNS GSEATGKYQG


 


151
NITFSADNPF GLSDMFYVNY GRSIGGTPDE ENFDGHRKEG GSNNYAVHYS


 


201
APFGKWTWAF NHNGYRYHQA VSGLSEVYDY NGKSYNTDFG FNRLLYRDAK


 


251
RKTYLSVKLW TRETKSYIDD AELTVQRRKT TGWLAELSHK GYIGRSTADF


 


301
KLKYKHGTGM KDALRAPEEA FGEGTSRMKI WTASADVNTP FQIGKQLFAY


 


351
DTSVHAQWNK TPLTSQDKLA IGGHHTVRGF DGEMSLPAER GWYWRNDLSW


 


401
QFKPGHQLYL GADVGHVSGQ SAKWLSGQTL AGTAIGIRGQ IKLGGNLHYD


 


451
IFTGRALKKP EYFQTKKWVT GFQVGYSF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2855>:










m930-1.seq




1
ATGAAACTTC CTTTATCCTA TTTGCCTAAT ATTCGCTTTT TGTCTTGGTG


 


51
CTGCTTATTG GCAGGTATCA TTGCTCCTGC TACTTTGTTG GCCTCCCCCA


 


101
ACCCTGCCGA AATCCGTATG CAGCAAGATA TTCAGCAACG CCAACGCGAA


 


151
GAGCAGTTGC GCCAAACCAT GCAGCCTGAA AGCGATGTGC GTTTGCATCA


 


201
AAAAAACACG GGGGAAACGG TTAATCAGTT GATGGGCGAT GACAGCAGCC


 


251
AACCGTGTTT TGCCATTAAC GAAGTGGTGT TGGAAGGCGA ACACCATGCT


 


301
CGGTTTCAGT TTGCCCTAAA ACGTGCCTTG CGCGAAACGG GTTTTCAGGC


 


351
TGGCAAGTGT CTGCATGCGG GCAACATTAA TCAAATCATG TCCTTAGCAC


 


401
AAAATGCTTT GATCGGCAGG GGATATACCA CGACCCGTAT CTTGGCTGCG


 


451
CCACAGGATT TGAATAGTGG CAAGCTTCAA TTAACCCTGA TACCGAGCTA


 


501
TCTGCGCTCC ATACGAATCG ATCGGTCTAA CGATGATCAA ACCCATGCAG


 


551
GACGTATTGC AGCATTCCAG AACAAATTTC CCACCCGCTC GAACGATCTG


 


601
TTGAATCTGC GTGATTTGGA ACAAGGACTG GAAAATCTCA AACGTCTCCC


 


651
GACTGCGGAA GCCGATCTCC AAATCGTTCC CGTAGAGGGA GAACCAAACC


 


701
AAAGTGATGT CGTGGTGCAA TGGCGGCAAC GTCTGCTGCC CTACCGTGTG


 


751
AGTGTGGGGA TGGATAATTC GGGTAGTGAG GCGACAGGAA AATACCAAGG


 


801
AAATATCACT TTCTCTGCCG ACAATCCTTT GGGACTGAGT GATATGTTCT


 


851
ATGTAAATTA TGGACGTTCG ATTGGCGGTA CGCCCGATGA GGAAAGTTTT


 


901
GACGGCCATC GCAAAGAAGG CGGATCAAAC AATTACGCCG TACATTATTC


 


951
AGCCCCTTTC GGTAAATGGA CATGGGCATT CAATCACAAT GGCTACCGTT


 


1001
ACCATCAGGC AGTTTCCGGA TTATCGGAAG TCTATGACTA TAATGGAAAA


 


1051
AGTTACAATA CTGATTTCGG CTTCAACCGC CTGTTGTATC GTGATGCCAA


 


1101
ACGCAAAACC TATCTCGGTG TAAAACTGTG GATGAGGGAA ACAAAAAGTT


 


1151
ACATTGATGA TGCCGAACTG ACTGTACAAC GGCGTAAAAC TGCGGGTTGG


 


1201
TTGGCAGAAC TTTCCCACAA AGAATATATC GGTCGCAGTA CGGCAGATTT


 


1251
TAAGTTGAAA TATAAACGCG GCACCGGCAT GAAAGATGCT CTGCGCGCGC


 


1301
CTGAAGAAGC CTTTGGCGAA GGCACGTCAC GTATGAAAAT TTGGACGGCA


 


1351
TCGGCTGATG TAAATACTCC TTTTCAAATC GGTAAACAGC TATTTGCCTA


 


1401
TGACACATCC GTTCATGCAC AATGGAACAA AACCCCGCTA ACATCGCAAG


 


1451
ACAAACTGGC TATCGGCGGA CACCACACCG TACGTGGCTT CGACGGTGAA


 


1501
ATGAGTTTGT CTGCCGAGCG GGGATGGTAT TGGCGCAACG ATTTGAGCTG


 


1551
GCAATTTAAA CCAGGCCATC AGCTTTATCT TGGGGCTGAT GTAGGACATG


 


1601
TTTCAGGACA ATCCGCCAAA TGGTTATCGG GCCAAACTCT AGTCGGCACA


 


1651
GCAATTGGGA TACGCGGGCA GATAAAGCTT GGCGGCAACC TGCATTACGA


 


1701
TATATTTACC GGCCGCGCAT TGAAAAAGCC CGAATTTTTC CAATCAAGGA


 


1751
AATGGGCAAG CGGTTTTCAG GTAGGCTATA CGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2856; ORF 930-1>:










m930-1.pep




1
MKLPLSYLPN IRFLSWCCLL AGIIAPATLL ASPNPAEIRM QQDIQQRQRE


 


51
EQLRQTMQPE SDVRLHQKNT GETVNQLMGD DSSQPCFAIN EVVLEGEHHA


 


101
RFQFALKRAL RETGFQAGKC LHAGNINQIM SLAQNALIGR GYTTTRILAA


 


151
PQDLNSGKLQ LTLIPSYLRS IRIDRSNDDQ THAGRIAAFQ NKFPTRSNDL


 


201
LNLRDLEQGL ENLKRLPTAE ADLQIVPVEG EPNQSDVVVQ WRQRLLPYRV


 


251
SVGMDNSGSE ATGKYQGNIT FSADNPLGLS DMFYVNYGRS IGGTPDEESF


 


301
DGHRKEGGSN NYAVHYSAPF GKWTWAFNHN GYRYHQAVSG LSEVYDYNGK


 


351
SYNTDFGFNR LLYRDAKRKT YLGVKLWMRE TKSYIDDAEL TVQRRKTAGW


 


401
LAELSHKEYI GRSTADFKLK YKRGTGMKDA LRAPEEAFGE GTSRMKIWTA


 


451
SADVNTPFQI GKQLFAYDTS VHAQWNKTPL TSQDKLAIGG HHTVRGFDGE


 


501
MSLSAERGWY WRNDLSWQFK PGHQLYLGAD VGHVSGQSAK WLSGQTLVGT


 


551
AIGIRGQIKL GGNLHYDIFT GRALKKPEFF QSRKWASGFQ VGYTF*






m930-1/g930-1 95.4% identity in 478 aa overlap





a930-1.seq not yet found

a930-1.pep not yet found

The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2857>:










g931.seq




1
ATGAAACCCA AATTCAAAAC CGTTTTAACC GCGCTGCTTT TGGCGGTTTC


 


51
CCTGCCGTCT ATGGCGGCAA CCCGCGTCCT GATGGAAACC GATATGGGCA


 


101
ATATCCGTTT GGTTTTGGAC GAATCCAAAG CCTCCAAAAC CGTTGCCAAT


 


151
TTCGTGCGCT ATGCCCGAAA AGGCTTTTAC GACAACACGA TTTTCCACCG


 


201
CGTcatCGGC GGCTTCGTCA TCCAAGGCGA CGGATTGACC GAGGACTTGG


 


251
TGCAAAAGGC AACCGATAAG GCCGTTGCCA ACGAATCCGG caacgGCTTG


 


301
AAAAACACCG TCGGCACCAT CGCAATGGCG CGGACGGCAG CCCCCGATTC


 


351
CGCCGCCGCC CAATTCTTTA TCAATCTGGC GGACAACGGT TCGCTCGACT


 


401
ACAAAAACGG ACAATACGGC TACACCGTTT TCGGCAGGGT AGAAAGCGGA


 


451
ATGGACACCG TTTCCAAAAT CGCCCGCGTC AAAACCGCCA CGCGCGGCTT


 


501
TTATCAAAAC GTACCCGTAC AGCCCGTCAA AATCCGTCGC GTTGTTGTCG


 


551
GGCAGTAACA CGCAGACAGA CGTTCAGACG GCGTCGCCCG TTTCCCAAAA


 


601
AACGCCGTTT AA






This corresponds to the amino acid sequence <SEQ ID 2858; ORF 931.ng>:










g931.pep




1
MKPKFKTVLT ALLLAVSLPS MAATRVLMET DMGNIRLVLD ESKASKTVAN


 


51
FVRYARKGFY DNTIFHRVIG GFVIQGDGLT EDLVQKATDK AVANESGNGL


 


101
KNTVGTIAMA RTAAPDSAAA QFFINLADNG SLDYKNGQYG YTVFGRVESG


 


151
MDTVSKIARV KTATRGFYQN VPVQPVKIRR VVVGQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2859>:










m931.seq




1
ATGAAACCCA AATTCAAAAC CGTTTTAACC GCGCTGCTTT TGGCGGTTTC


 


51
CCTGCCGTCT ATGGCGGCAA CCCATGTTTT GATGGAAACC GATATGGGCA


 


101
ATATCCGTTT GGTTTTGGAC GAATCCAAAG CCCCCAAAAC CGTTGCTAAT


 


151
TTCGTGCGCT ATGCCCGAAA AGGCTTTTAC GACGACACCG TTTTTCACCG


 


201
CGTTATCGAC GGTTTTGTTA TCCAGGGCGG TGGATTGACC GAGGACTTGG


 


251
CACAAAAGGC AAGCGATAAG GCCGTTGCCA ACGAATCCGG CAACGGCTTG


 


301
AAAAACACCG CCGGCACCAT CGCCATGGCG CGGACGACAG CCCCCGATTC


 


351
CGCCACCAGC CAATTCTTTA TCAATCTGGC GGACcA.kCT TCGCTCGACT


 


401
ACAAAAACGG ACAATACGGC TATACCGTTT TCGGCAGGGT CGAAAGCGGC


 


451
ATGAACACCG TTTCCAAAAT CGCCCGCGTC AAAACCGCCA CGCGCGGCTT


 


501
TTATCAAAAC GTACCCGTAC AGCCCGTCAA AATCCGTCGC GTTGTTGTCG


 


551
GGCAGTAA






This corresponds to the amino acid sequence <SEQ ID 2860; ORF 931>:










m931.pep..




1
MKPKFKTVLT ALLLAVSLPS MAATHVLMET DMGNIRLVLD ESKAPKTVAN


 


51
FVRYARKGFY DDTVFHRVID GFVIQGGGLT EDLAQKASDK AVANESGNGL


 


101
KNTAGTIAMA RTTAPDSATS QFFINLADXX SLDYKNGQYG YTVFGRVESG


 


151
MNTVSKIARV KTATRGFYQN VPVQPVKIRR VVVGQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae ORF 931 shows 91.9% identity over a 185 aa overlap with a predicted ORF (ORF 931.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2861>:










a931.seq




1
ATGAAACCCA AATTCAAAAC CGTTTTAACC GCGCTGCTTT TGGCGGTTTC


 


51
CCTGCCGTCT ATGGCGGCAA CCCATGTTTT GATGGAAACC GATATGGGCA


 


101
ATATCCGTTT GGTTTTGGAC GAATCCAAAG CACCCAAAAC CGTTGCCAAT


 


151
TTCGTGCGCT ATGCCCGAAA AGGCTTTTAC GACAATACGA TTTTTCACCG


 


201
CGTCATCGGC GGCTTCGTTA TCCAAGGCGG CGGATTGACC GAGGACTTGG


 


251
CACAAAAGGC AAGCGATAAG GCCGTTGCCA ACGAATCCGG CAACGGCTTG


 


301
AAAAACACTG TCGGCACCAT CGCCATGGCG CGGACGGCCG ATCCGGATTC


 


351
CGCCACCAGC CAATTCTTTA TCAATCTGGT GGACAATGAT TCGCTCAACT


 


401
ACAAAAACGG ACAATACGGC TATACCGTTT TCGGCAGGGT CGAAAGCGGC


 


451
ATGAACACCG TTTCCAAAAT CGCCCGCGTC AAAACCGCCA CGCGCGGCTT


 


501
TTATCAAAAC GTACCCGTAC AGCCCGTCAA AATCCGTCGC GTTGTTGTCG


 


551
GGCAGTAA






This corresponds to the amino acid sequence <SEQ ID 2862; ORF 931.a>:










a931.pep




1
MKPKFKTVLT ALLLAVSLPS MAATHVLMET DMGNIRLVLD ESKAPKTVAN


 


51
FVRYARKGFY DNTIFHRVIG GFVIQGGGLT EDLAQKASDK AVANESGNGL


 


101
KNTVGTIAMA RTADPDSATS QFFINLVDND SLNYKNGQYG YTVFGRVESG


 


151
MNTVSKIARV KTATRGFYQN VPVQPVKIRR VVVGQ*






m931/a931 94.6% identity in 185 aa overlap





g932.seq not found yet

g932.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2863>:










m932.seq




1
ATGAAATATA TCGTATCAAT CTCTCTGGCT ATGGGATTGG CTGCCTGTTC


 


51
GTTTGGGGGA TTTAAACCAA ATCCGTGGGA CGCCGCGTCA TTTTGGGAAT


 


101
TGAAAAATTA CGCCAATCCC TATCCGGGAT CAGCCTCGGC GGCACTTGAC


 


151
CAATATCCAT CGAAAGCAAG ACGAAGGCAA CTGAAAGACA TGCAAGAGTG


 


201
CGGCTATGAC CCAATAGACG GCGGAAAGTC TGAAGCAGAT GCCTGCCTGA


 


251
GGAAAAAAGG CTGGTGTCGT AAGGGTTTCG ACCCTTATCC CGAAAACAAA


 


301
AAATACGAAT GGCCTCGAGA AGAAGGAAAA ACAAAATGA






This corresponds to the amino acid sequence <SEQ ID 2864; ORF 932>:










m932.pep




1
MKYIVSISLA MGLAACSFGG FKPNPWDAAS FWELKNYANP YPGSASAALD


 


51
QYPSKARRRQ LKDMQECGYD PIDGGKSEAD ACLRKKGWCR KGFDPYPENK


 


101
KYEWPREEGK TK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 932 shows ——————% identity over a —————— aa overlap with a predicted ORF (ORF 932.ng) from N. gonorrhoeae: 

The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2865>:










g934.seq




1
ATGAAAAAAA TCATCGCCTC CGCGCTTATC GCAACATTCG CACTCACCGC


 


51
CTGCCAAGAC GACACGCAGG CGCGGCTCGA ACGGCAGCAG AAACAGATTG


 


101
AAGCCCTGCA ACAGCAGCTC GCACAGCAGG CAGACGATAC GGTTTACCAA


 


151
CTGACTCCCG AAGCAGTCAA AGACACCATT CCTGCCCAGG CGCAGGCAAA


 


201
CGGCAACAAC GGTCAGCCCG TTACCGGCAA .AGAcggGCA GCAGTATATT


 


251
TACGACCAAT CGACAGGAAG CTGGCTGCTG CAAAGCCTGA TTGGCGCGGC


 


301
GGCAGGCGCG TTTATCGGCA ACGCGCTGGC AAACAAATTC ACACGGGCGG


 


351
GCAACCAAGA CAGCCCCGTC GCCCGTCGCG CGCGTGCTGC CTACCATCAG


 


401
TCCGCACGCC CCAATGCGCG CACCAGCAGG GATTTGAACA CGCGCAGCCT


 


451
CCGTGCAAAA CAACAGGCGG CGCAGGCGCA GCGTTACCGC CCGACAACGC


 


501
GCCCGCCCGT CAAttaccgc catcgcgcta tgcGCGGTTT CGgcagAagg


 


551
cggtaaaCCC GGCGCGTCAA TGCCGTCTGA AGGGCTTTCA GACGGCATTT


 


601
TTGTATTTGT TAGGGGCATT GTTATGTTGC CGTTTGATTT TCAGACGGCA


 


651
TTTTGTTTCC AAGCGTTTGA TGTcggGATG GCAATTCTGA






This corresponds to the amino acid sequence <SEQ ID 2866; ORF 934.ng>:










g934.pep




1
MKKIIASALI ATFALTACQD DTQARLERQQ KQIEALQQQL AQQADDTVYQ


 


51
LTPEAVKDTI PAQAQANGNN GQPVTGKRRA AVYLRPIDRK LAAAKPDWRG


 


101
GRRVYRQRAG KQIHTGGQPR QPRRPSRACC LPSVRTPQCA HQQGFEHAQP


 


151
PCKTTGGAGA ALPPDNAPAR QLPPSRYARF RQKAVNPARQ CRLKGFQTAF


 


201
LYLLGALLCC RLIFRRHFVS KRLMSGWQF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2867>:









m934.seq (partial)










1
..CGGCTCGAAC AGCAGCAGAA ACAGATTGAA GCCCTGCAAC AGCAGCTCGC



 


51
  ACAGCAGGCA GACGATACGG TTTACCAACT GACTCCCGAA GCAGTCAAAG


 


101
  ACACCATTCC TGCCGAAGCA CAGGCAAACG GCAACAACgG GCAACCCGTT


 


151
  ACCGGTAA.A GACGGGCAGC AGTATATTTA CGACCAATCG ACAGGAAGCT


 


201
  GGCTGCTGCA AAGCCTGGTC GGCGCGGCGG CAGGCGCGTT TATCGGCAAC


 


251
  GCGCTGGCAA ACAAATTCAC ACGGGCAGGC AACCAAGACA GTCCCGTCGC


 


301
  CCGGCGCGCG CGTGCAGCCT ACCATCAGTC CGCACGCCCC AATGCGCGCA


 


351
  yCAGCAGGGA TTTGAACACG CGCAGCCTCC GTGCAAAACA ACAGGCGGCG


 


401
  CAkGCGCAGC GTTACCGCCC GACAACGCGC CCGsCCGsCA ATTACCGCCG


 


451
  CCCCGCTATG CGCGGTTTCG GCAGGAGGCG GTAAACCCGG CGCGCCAATG


 


501
  CCGTCTGAAG AGCTTTCAGA CGGCATTTnT GCATTTGTTA GGGACATTGT


 


551
  TATGTTGCCG TTTGATTTTC AGACGGCATT TTGTTTCCAA GCGTTTGATG


 


601
  TCGGGATGGC AATTCTGA






This corresponds to the amino acid sequence <SEQ ID 2868; ORF 934>:









m934.pep (partial)










1
..RLEQQQKQIE ALQQQLAQQA DDTVYQLTPE AVKDTIPAEA QANGNNGQPV



 


51
  TGXRRAAVYL RPIDRKLAAA KPGRRGGRRV YRQRAGKQIH TGRQPRQSRR


 


101
  PARACSLPSV RTPQCAHQQG FEHAQPPCKT TGGAXAALPP DNAPXRQLPP


 


151
  PRYARFRQEA VNPARQCRLK SFQTAFXHLL GTLLCCRLIF RRHFVSKRLM


 


201
  SGWQF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 934 shows 91.7% identity over a 205 aa overlap with a predicted ORF (ORF 934.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2869>:










a934.seq




1
ATGAAAAAAA TCATCGCCTC CGCGCTTATC GCAACATTCG CACTCGCCGC


 


51
CTGCCAAGAC GACGCGCAGG CGCGGCTCGA ACAGCAGCAG AAACAGATTG


 


101
AAGCCCTGCA ACAGCAGCTC GCACAGCAGG CAGACGATAC GGTTTACCAA


 


151
CTGACTCCCG AAGCAGTCAA AGACACCATT CCTGCCGAAG CACAGGCAAA


 


201
CGGCAACAAC GGGCAACCCG TTACCGG.TA AAGACGGGCA GCAGTATATT


 


251
TACGACCAAT CGACAGGAAG CTGGCTGCTG CAAAGCCTGG TCGGCGCGGC


 


301
GGCAGGCGCG TTTATCGGCA ACGCGCTGGC AAACAAATTC ACACGGGCAG


 


351
GCAACCAAGA CAGTCCCGTC GGCAGGCGCG CGCGTGCCGC CTACCATCAG


 


401
TCCGCACATC CCAATGCGCG CACCAGCAGG GATTTGAACA CGCGCAGCCT


 


451
CCGTGCAAAA CAACAGGCGG CGCAGGCGCA GCGTTACCGC CCGACAACGC


 


501
GCCCGCCCGC CAATTACCGC CGCCCCGCCA TGCGCGGTTT CGGCAGAAGG


 


551
CGGTAAATCC GGCGTGCCAA TGCCGTCTGA AGGGCTTTCA GACGGCATTT


 


601
TTGTATTTGT TAGGGACATT GTTATGTTGC CGTTTGATTT TTAGACGGCA


 


651
TTTTGTTTCC AAGAGTTTGA TGTCGGGATG GCAATTCTGA






This corresponds to the amino acid sequence <SEQ ID 2870; ORF 934.a>:










a934.pep




1
MKKIIASALI ATFALAACQD DAQARLEQQQ KQIEALQQQL AQQADDTVYQ


 


51
LTPEAVKDTI PAEAQANGNN GQPVTX*RRA AVYLRPIDRK LAAAKPGRRG


 


101
GRRVYRQRAG KQIHTGRQPR QSRRPARACR LPSVRTSQCA HQQGFEHAQP


 


151
PCKTTGGAGA ALPPDNAPAR QLPPPRHARF RQKAVNPACQ CRLKGFQTAF


 


201
LYLLGTLLCC RLIFRRHFVS KSLMSGWQF*






m934/a934 94.1% identity in 205 aa overlap





g935.seq not found yet

g935.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2871>:










m935.seq




1
ATGTTGTATT TCAGATACGG CTTTTTGGTT GTTTGGTGTG CGGCAGGTGT


 


51
TTCTGCCGCC TATGGGGCGG ATGCGCCCGC GATTTTGGAT GACAAGGCAT


 


101
TGTTGCAGGT GCAGCGGTCG GTGTCGGATA AGTGGGCGGA ATCAGATTGG


 


151
AAAGTTGAAA ATGATGCCCC GCGCGTGGTT GACGGGGATT TTTTGTTGGC


 


201
GCATCCGAAA ATGTTGGAAC ATAGTTTGCG CGACGCGCTC AACGGCAATC


 


251
AGGCGGATTT AATCGCTTCG TTGGCGGATT TGTATGCCAA GCTGCCGGAT


 


301
TATGACGCGG TTTTGTACGG CAGGGCGCGG GCTTTGCTGG CGAAATTGGC


 


351
GGGAAGGCCG GCGGAGGCGG TGGCGCGGTA TCGGGAACTG CACGGGGAAA


 


401
ATGCGGCAGA CGAGCGGATT TTGCTGGATT TGGCGGCGGC GGAGTTTGAC


 


451
GATTTCCGGC TGAAGTCGGC AGAAAGGCAT TTTGCGGAGG CGGCAAAATT


 


501
GGATTTGCCG GCACCGGTTT TGGAAAATGT GGGGCGTTTT CGGAAAAAAA


 


551
CGGAGGGGCT GACGGGCTGG CGTTTTTCGG GCGGCATCAG TCCGGCGGTC


 


601
AATAGAAATG CCAATAATGC CGCGCCGCAA TATTGCCGGC AAAACGGAGG


 


651
CCGGCAGATA TGCAGTGTCA GCCGGGCGGA GCGGGCGGCA GGGTTGAATT


 


701
ATGAAATCGA GGCGGAAAAG CTGACGCCGT TGGCAGATAA TCATTATTTG


 


751
TTGTTCCGTT CCAATATCGG CGGCACGAGC TATTATTTCA GTAAAAAATC


 


801
AGCTTATGAT GACGGGTTCG GCAGGGCGTA TTTGGGTTGG CAGTATAAAA


 


851
ATGCACGGCA GACGGCGGGG ATTTTGCCGT TTTATCAGGT GCAGTTGTCG


 


901
GGCAGCGACG GCTTTGATGC GAAAACAAAA CGGGTAAACA ACCGCCGCCT


 


951
GCCGCCGTAT ATGCTGGCGC ACGGAGTCGG CGTGCAGCTG TCCCATACTT


 


1001
ACCGCCCAAA CCCGGGATGG CAATTTTCGG TCGCGCTGGA ACATTACCGC


 


1051
CAACGCTACC GCGAACAGGA TAGGGCGGAA TACAATAACG GCAGGCAGGA


 


1101
CGGGTTTTAT GTTTCGTCGG CAAAACGTTT GGGCGAATCG GCAACTGTGT


 


1151
TCGGCGGCTG GCAGTTTGTG CGGTTTGTGC CGAAACGCGA AACGGTGGGC


 


1201
GGCGCGGTCA ATAATGCCGC CTACCGGCGC AACGGTGTTT ATGCCGGTTG


 


1251
GGCGCAGGAG TGGCGGCAGT TGGGCGGTTT GAACAGTCGG GTTTCCGCGT


 


1301
CTTATGCCCG CCGCAACTAT AAGGGCATTG CGGCTTTCTC GACAGAGGCG


 


1351
CAACGCAACC GCGAATGGAA TGTCTCGCTG GCTTTGAGCC ACGACAAGTT


 


1401
GTCGTACAAA GGTATCGTGC CGGCGTTGAA TTATCGTTTC GGCAGGACGG


 


1451
AAAGTAATGT GCCGTATGCG AAACGCCGCA ACAGCGAGGT GTTTGTGTCG


 


1501
GCGGATTGGC GGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 2872; ORF 935>:










m935.pep




1
MLYFRYGFLV VWCAAGVSAA YGADAPAILD DKALLQVQRS VSDKWAESDW


 


51
KVENDAPRVV DGDFLLAHPK MLEHSLRDAL NGNQADLIAS LADLYAKLPD


 


101
YDAVLYGRAR ALLAKLAGRP AEAVARYREL HGENAADERI LLDLAAAEFD


 


151
DFRLKSAERH FAEAAKLDLP APVLENVGRF RKKTEGLTGW RFSGGISPAV


 


201
NRNANNAAPQ YCRQNGGRQI CSVSRAERAA GLNYEIEAEK LTPLADNHYL


 


251
LFRSNIGGTS YYFSKKSAYD DGFGRAYLGW QYKNARQTAG ILPFYQVQLS


 


301
GSDGFDAKTK RVNNRRLPPY MLAHGVGVQL SHTYRPNPGW QFSVALEHYR


 


351
QRYREQDRAE YNNGRQDGFY VSSAKRLGES ATVFGGWQFV RFVPKRETVG


 


401
GAVNNAAYRR NGVYAGWAQE WRQLGGLNSR VSASYARRNY KGIAAFSTEA


 


451
QRNREWNVSL ALSHDKLSYK GIVPALNYRF GRTESNVPYA KRRNSEVFVS


 


501
ADWRF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2873>:










a935.seq




1
ATGTTGTATT TCAGATACGG TTTTTTGGTT GTTTGGTGTG CGGCAGGTGT


 


51
TTCTGCCGCC TATGGGGCGG ATGCGCCCGC GATTTTGGAT GACAAGGCAT


 


101
TGTTGCAGGT GCAGCGGTCG GTGTCGGATA AGTGGGCGGA ATCGGATTGG


 


151
AAAGTTGACA ATGATGCCCC GCGCGTGGTT GACGGGGATT TTTTGTTGGC


 


201
GCATCCGAAA ATGTTGGAAC ATAGTTTGCG CGACGTGCTC AACGGCAATC


 


251
AGGCGGATTT GATCGCTTCG TTGGCGGATT TGTATGCCAA GCTGCCGGAT


 


301
TATGACGCGG TTTTGTACGG CAGGGCGCGG GCTTTGCTGG CGAAATTGGC


 


351
GGGAAGGCCG GCGGAGGCGG TGGCGCGGTA TCGGGAACTG CACGGGGAAA


 


401
ATGCGGCAGA CGAGCGGATT TTGCTGGATT TGGCGGCGGC GGAGTTTGAC


 


451
GATTTCCGGC TGAAGTCGGC AGAAAGGCAT TTTGCCGAGG CGGAAAAATT


 


501
GGATTTGCCG GCGCCGGTTT TGGAAAATGT GGGGCGTTTT CGGAAAAAAG


 


551
CGGAGGGGCT GACGGGCTGG CGTTTTTCGG GCGGCATCAG TCCGGCGGTC


 


601
AATAGAAATG CCAATAATGC CGCGCCGCAG TATTGCCGGC AAAACGGAGG


 


651
CCGGCAGATA TGCAGTGTCA GCCGGGCGGA GCGGGCGGCA GGCTTGAATT


 


701
ATGAAATCGA GGCGGAAAAA CTGACGGCGT TGGCAGATAA TCATTATTTG


 


751
TTGTTCCGTT CCAATATCGG CGGCACGAGC TATTATTTCA GTAAAAAATC


 


801
AGCTTATGAC GACGGGTTCG GCAGAGCGTA TTTGGGTTGG CAGTATAAAA


 


851
ATGCACGGCA GACGGCGGGG ATTTTGCCGT TTTATCAGGT GCAGTTGTCG


 


901
GGCAGCGACG GCTTTGATGC GAAAACAAAA CGGGTAAACA ACCGCCGCCT


 


951
GCCGCCGTAT ATGCTGGCGC ACGGAGTCGG CGTGCAGTTG TCCCATACTT


 


1001
ACCGCCCAAA CCCGGGATGG CAATTTTCGG TCGCGCTGGA ACATTACCGC


 


1051
CAACGCTACC GCGAACAGGA TAGGGCGGAA TACAATAACG GTCGGCAGGA


 


1101
CGGGTTTTAT GTTTCGTCGG CAAAACGTTT GGGCGAATCG GCAACTGTGT


 


1151
TCGGCGGCTG GCAGTTTGTG CGGTTTGTGC CGAAACGCGA AACGGTGGGC


 


1201
GGCGCGGTCA ATAATGCCGC CTACCGGCGC AACGGTGTTT ATGCCGGCTG


 


1251
GGCGCAGGAG TGGCGGCAGT TGGGCGGTTT GAACAGTCGG GTTTCCGCGT


 


1301
CTTATGCCCG CCGCAACTAT AAGGGCGTTG CGGCTTTCTC GACAGAGGCG


 


1351
CAACGCAACC GCGAATGGAA TGTCTCGCTG GCTTTGAGCC ACGACAAGTT


 


1401
GTCGTACAAA GGTATCGTGC CCGCGTTGAA TTATCGTTTC GGCAGGACGG


 


1451
AAAGTAATGT GCCGTATGCG AAACGCCGCA ACAGCGAGGT GTTTGTGTCG


 


1501
GCGGATTGGC GGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 2874; ORF 935.a>:










a935.pep




1
MLYFRYGFLV VWCAAGVSAA YGADAPAILD DKALLQVQRS VSDKWAESDW


 


51
KVDNDAPRVV DGDFLLAHPK MLEHSLRDVL NGNQADLIAS LADLYAKLPD


 


101
YDAVLYGRAR ALLAKLAGRP AEAVARYREL HGENAADERI LLDLAAAEFD


 


151
DFRLKSAERH FAEAEKLDLP APVLENVGRF RKKAEGLTGW RFSGGISPAV


 


201
NRNANNAAPQ YCRQNGGRQI CSVSRAERAA GLNYEIEAEK LTALADNHYL


 


251
LFRSNIGGTS YYFSKKSAYD DGFGRAYLGW QYKNARQTAG ILPFYQVQLS


 


301
GSDGFDAKTK RVNNRRLPPY MLAHGVGVQL SHTYRPNPGW QFSVALEHYR


 


351
QRYREQDRAE YNNGRQDGFY VSSAKRLGES ATVFGGWQFV RFVPKRETVG


 


401
GAVNNAAYRR NGVYAGWAQE WRQLGGLNSR VSASYARRNY KGVAAFSTEA


 


451
QRNREWNVSL ALSHDKLSYK GIVPALNYRF GRTESNVPYA KRRNSEVFVS


 


501
ADWRF*






m935/a935 98.8% identity in 505 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2875>:










g936.seq




1
ATGAAACCCA AACCACACAC CGTCCGCACC CTGATTGCCG CCGTCCTCAG


 


51
CCTTGCCCTC GGCGGCTGCT TCAGCGCAGT CGTCGGCGGG GCCGCCGTCG


 


101
GCGCAAAATC CGTCATCGAC CGccgAACCA CCGgcgcgca AACCGATGac


 


151
aACGTTATGG CGTTGCGTAT CGAAACCACC GCCCGTTCCT ACCTGCGCCA


 


201
AAACAACCAA ACCAAAGGCT ACACGCCCCA AATCTCCGTC GTCGGCTACA


 


251
ACCGCCACCT GCTGCTGCTC GGACAAGTCG CCACCGAAGG CGAAAAACAG


 


301
TTCGTCGGTC AGATTGCACG TTCCGAACAG GCCGCCGAAG GCGTATACAA


 


351
CTACATTACC GTCGCCTCCC TGCCGCGCAC TGCGGGCGAC ATCGCCGGCG


 


401
ACACTTGGAA CACGTCCAAA GTCCGCGCca cgCTGCTGGG CATCAGCCCC


 


451
GCTACACAGG CGCGCGTCAA AATCATTACC TACGGCAATG TAACCTACGT


 


501
TATGGGCATC CTCACCCCCG AAGAACAGGC GCAGATTACC CAAAAAGTCA


 


551
GCACCAccgT CGGCGTACAA AAAGTCATTA CCCTCTACCA AAACTACGTC


 


601
CAACGCTGA






This corresponds to the amino acid sequence <SEQ ID 2876; ORF 936.ng>:










g936.pep




1
MKPKPHTVRT LIAAVLSLAL GGCFSAVVGG AAVGAKSVID RRTTGAQTDD


 


51
NVMALRIETT ARSYLRQNNQ TKGYTPQISV VGYNRHLLLL GQVATEGEKQ


 


101
FVGQIARSEQ AAEGVYNYIT VASLPRTAGD IAGDTWNTSK VRATLLGISP


 


151
ATQARVKIIT YGNVTYVMGI LTPEEQAQIT QKVSTTVGVQ KVITLYQNYV


 


201
QR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2877>:









m936.seq (partial)










1
ATGAAACCCA AACCGCACAC CGTCCGCACC CTGATTGCCG CCATTTTCAG



 


51
CCTTGCCCTT AGCGGCTGCG TCAGCGCAGT AATCGGAAGC GCCGCCGTCG


 


101
GCGCGAAATC CGCCGTCGAC CGCCGAACCA CCGGCGCGCA AACCGACGAC


 


151
AACGTTATGG CGTTGCGTAT CGAAACCACC GCCCGTTCCT ATCTGCGCCA


 


201
AAACAACCAA ACCAAAGGCT ACACGCCCCA AATCTCCGTC GTCGGCTACA


 


251
ACCGCCACCT GCTGCTGCTC GGACAAGTCG CCACCGAAGG CGAAAAACAG


 


301
TTCGTCGGTC AGATTGCACG TTCCGAACAG GCCGCCGAAG GCGTGTACAA


 


351
CTATATTACC GTCGCCTCCC TGCCGCGCAC TGCC...






This corresponds to the amino acid sequence <SEQ ID 2878; ORF 936>:









m936.pep (partial)










1
MKPKPHTVRT LIAAIFSLAL SGCVSAVIGS AAVGAKSAVD RRTTGAQTDD



 


51
NVMALRIETT ARSYLRQNNQ TKGYTPQISV VGYNRHLLLL GQVATEGEKQ


 


101
FVGQIARSEQ AAEGVYNYIT VASLPRTA...






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 936 shows 93.8% identity over a 128 aa overlap with a predicted ORF (ORF 936.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2879>:










a936.seq




1
ATGAAACCCA AACCGCACAC CGTCCGCACC CTGACTGCCG CCGTCCTCAG


 


51
CCTTGCCCTC GGCGGCTGCG TCAGCGCAGT CGTCGGCGGC GCGGCGGTCG


 


101
GCGCGAAATC CGCCGTCGAC CGCCGAACCA CCGGCGCGCA AACCGACGAC


 


151
AACGTAATGG CGCTGCGTAT CGAAACCACC GCCCGCTCCT ATCTGCGCCA


 


201
AAACAACCAA ACCAAAGGCT ACACGCCCCA AATCTCCGTT GTCGGCTACA


 


251
ACCGCCACCT GCTGCTGCTC GGACAAGTCG CCACCGAAGG CGAGAAACAG


 


301
TTCGTCGGTC AGATTGCACG TTCCGAACAG GCCGCCGAAG GCGTGTACAA


 


351
CTACATTACC GTCGCCTCCC TGCCGCGCAC TGCCGGCGAC ATCGCCGGCG


 


401
ACACTTGGAA CACATCCAAA GTCCGCGCCA CGCTGTTGGG CATCAGCCCC


 


451
GCCACACAGG CGCGCGTCAA AATCGTTACC TACGGCAACG TAACCTACGT


 


501
TATGGGCATC CTCACCCCCG AAGAACAGGC GCAGATTACC CAAAAAGTCA


 


551
GCACCACCGT CGGCGTACAA AAAGTCATCA CCCTCTACCA AAACTACGTC


 


601
CAACGCTGA






This corresponds to the amino acid sequence <SEQ ID 2880; ORF 936.a>:










a936.pep




1
MKPKPHTVRT LTAAVLSLAL GGCVSAVVGG AAVGAKSAVD RRTTGAQTDD


 


51
NVMALRIETT ARSYLRQNNQ TKGYTPQISV VGYNRHLLLL GQVATEGEKQ


 


101
FVGQIARSEQ AAEGVYNYIT VASLPRTAGD IAGDTWNTSK VRATLLGISP


 


151
ATQARVKIVT YGNVTYVMGI LTPEEQAQIT QKVSTTVGVQ KVITLYQNYV


 


201
QR*






m936/a936 95.3% identity in 128 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2881>:










g936-1.seq




1
ATGAAACCCA AACCACACAC CGTCCGCACC CTGATTGCCG CCGTCCTCAG


 


51
CCTTGCCCTC GGCGGCTGCT TCAGCGCAGT CGTCGGCGGG GCCGCCGTCG


 


101
GCGCAAAATC CGTCATCGAC CGccgAACCA CCGgcgcgca AACCGATGac


 


151
aACGTTATGG CGTTGCGTAT CGAAACCACC GCCCGTTCCT ACCTGCGCCA


 


201
AAACAACCAA ACCAAAGGCT ACACGCCCCA AATCTCCGTC GTCGGCTACA


 


251
ACCGCCACCT GCTGCTGCTC GGACAAGTCG CCACCGAAGG CGAAAAACAG


 


301
TTCGTCGGTC AGATTGCACG TTCCGAACAG GCCGCCGAAG GCGTATACAA


 


351
CTACATTACC GTCGCCTCCC TGCCGCGCAC TGCGGGCGAC ATCGCCGGCG


 


401
ACACTTGGAA CACGTCCAAA GTCCGCGCca cgCTGCTGGG CATCAGCCCC


 


451
GCTACACAGG CGCGCGTCAA AATCATTACC TACGGCAATG TAACCTACGT


 


501
TATGGGCATC CTCACCCCCG AAGAACAGGC GCAGATTACC CAAAAAGTCA


 


551
GCACCAccgT CGGCGTACAA AAAGTCATTA CCCTCTACCA AAACTACGTC


 


601
CAACGCTGA






This corresponds to the amino acid sequence <SEQ ID 2882; ORF 936-1.ng>:










g936-1.pep




1
MKPKPHTVRT LIAAVLSLAL GGCFSAVVGG AAVGAKSVID RRTTGAQTDD


 


51
NVMALRIETT ARSYLRQNNQ TKGYTPQISV VGYNRHLLLL GQVATEGEKQ


 


101
FVGQIARSEQ AAEGVYNYIT VASLPRTAGD IAGDTWNTSK VRATLLGISP


 


151
ATQARVKIIT YGNVTYVMGI LTPEEQAQIT QKVSTTVGVQ KVITLYQNYV


 


201
QR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2883>:










m936-1.seq




1
ATGAAACCCA AACCGCACAC CGTCCGCACC CTGATTGCCG CCATTTTCAG


 


51
CCTTGCCCTT AGCGGCTGCG TCAGCGCAGT AATCGGAAGC GCCGCCGTCG


 


101
GCGCGAAATC CGCCGTCGAC CGCCGAACCA CCGGCGCGCA AACCGACGAC


 


151
AACGTTATGG CGTTGCGTAT CGAAACCACC GCCCGTTCCT ATCTGCGCCA


 


201
AAACAACCAA ACCAAAGGCT ACACGCCCCA AATCTCCGTC GTCGGCTACA


 


251
ACCGCCACCT GCTGCTGCTC GGACAAGTCG CCACCGAAGG CGAAAAACAG


 


301
TTCGTCGGTC AGATTGCACG TTCCGAACAG GCCGCCGAAG GCGTGTACAA


 


351
CTATATTACC GTCGCCTCCC TGCCGCGCAC TGCCGGCGAC ATCGCCGGCG


 


401
ACACTTGGAA CACATCCAAA GTCCGCGCCA CGCTGTTGGG CATCAGCCCC


 


451
GCCACACAGG CGCGCGTCAA AATCGTTACC TACGGCAACG TAACCTACGT


 


501
TATGGGCATC CTCACCCCCG AAGAACAGGC GCAGATTACC CAAAAAGTCA


 


551
GCACCACCGT CGGCGTACAA AAAGTCATCA CCCTCTACCA AAACTACGTC


 


601
CAACGCTGA






This corresponds to the amino acid sequence <SEQ ID 2884; ORF 936-1>:










m936-1.pep




1
MKPKPHTVRT LIAAIFSLAL SGCVSAVIGS AAVGAKSAVD RRTTGAQTDD


 


51
NVMALRIETT ARSYLRQNNQ TKGYTPQISV VGYNRHLLLL GQVATEGEKQ


 


101
FVGQIARSEQ AAEGVYNYIT VASLPRTAGD IAGDTWNTSK VRATLLGISP


 


151
ATQARVKIVT YGNVTYVMGI LTPEEQAQIT QKVSTTVGVQ KVITLYQNYV


 


201
QR*






m936-1/g936-1 95.5% identity in 202 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2885>:










a936-1.seq




1
ATGAAACCCA AACCGCACAC CGTCCGCACC CTGACTGCCG CCGTCCTCAG


 


51
CCTTGCCCTC GGCGGCTGCG TCAGCGCAGT CGTCGGCGGC GCGGCGGTCG


 


101
GCGCGAAATC CGCCGTCGAC CGCCGAACCA CCGGCGCGCA AACCGACGAC


 


151
AACGTAATGG CGCTGCGTAT CGAAACCACC GCCCGCTCCT ATCTGCGCCA


 


201
AAACAACCAA ACCAAAGGCT ACACGCCCCA AATCTCCGTT GTCGGCTACA


 


251
ACCGCCACCT GCTGCTGCTC GGACAAGTCG CCACCGAAGG CGAGAAACAG


 


301
TTCGTCGGTC AGATTGCACG TTCCGAACAG GCCGCCGAAG GCGTGTACAA


 


351
CTACATTACC GTCGCCTCCC TGCCGCGCAC TGCCGGCGAC ATCGCCGGCG


 


401
ACACTTGGAA CACATCCAAA GTCCGCGCCA CGCTGTTGGG CATCAGCCCC


 


451
GCCACACAGG CGCGCGTCAA AATCGTTACC TACGGCAACG TAACCTACGT


 


501
TATGGGCATC CTCACCCCCG AAGAACAGGC GCAGATTACC CAAAAAGTCA


 


551
GCACCACCGT CGGCGTACAA AAAGTCATCA CCCTCTACCA AAACTACGTC


 


601
CAACGCTGA






This corresponds to the amino acid sequence <SEQ ID 2886; ORF 936-1.a>:










a936-1.pep




1
MKPKPHTVRT LTAAVLSLAL GGCVSAVVGG AAVGAKSAVD RRTTGAQTDD


 


51
NVMALRIETT ARSYLRQNNQ TKGYTPQISV VGYNRHLLLL GQVATEGEKQ


 


101
FVGQIARSEQ AAEGVYNYIT VASLPRTAGD IAGDTWNTSK VRATLLGISP


 


151
ATQARVKIVT YGNVTYVMGI LTPEEQAQIT QKVSTTVGVQ KVITLYQNYV


 


201
QR*






a936-1/m936-1 97.0% identity in 202 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae<SEQ ID 2887>:










g937.seq




1
atGAAAAATA TTCTCTTAgt ATTTGTTAGC TTTGTGCCAT TATGTGTCCG


 


51
CACTGATCTG CCGCTGAata tCGAAGACAT AATGaccgAC AAGGGAAAAT


 


101
GGAAactGGA AACTTccctt acctacctgA acaGCGAAAA cagCCGCGCC


 


151
GCACTTGCCT CACCGGTTTA CATTCAGACC GGCTCCGCTT CCTTTATCCC


 


201
CGTCCCGACC GAAATTCAGG AAAACGGCAG CAATACCGAT ATGCTCGCCG


 


251
GCACGCTCGG TTTGCGCTAC GGACTGAccg GCAataccgA CATTTACGGC


 


301
AGCGGCAGCT ATCTGTGGCA CGAAGAACGC AAACTCGacg GCAACGGCAA


 


351
AACCCGCAAC AAACGGATGT CCGACATATC CGCCGGCATC AGCCACACCT


 


401
TCCttaAAGa cgGCAAAAAT CCCGCACTCA TCGCTTTCCT CGAAAGCACG


 


451
GTTTACGAAA AATCGCGCAA CAAAGCCTCG TCGGGAAAAT CGTGGCTCAT


 


501
CGGCGCCACC ACCTACAAAG CCATAGATCC GATTGTCCTT TCCCTCACCG


 


551
CCGCCTACCG CATCAACGGC AGCAAAACCC TTTCAGACGA CGTCAAATAC


 


601
AAAGCAGGCA ATTACTGGAT GCTGAATCCC AACATCTCAT TTGCCGCCAA


 


651
CGACAGAATC AGCCTGACCG GAGGCATCCA ATGGCTGGGC AAACAGCCCG


 


701
ACCGCATAGA CGGCAAAAAA GAATCCGCAA GAAACACATC CACCTACGCC


 


751
CATTTCGGCG CAGGTTTCGG TTTCACCAAA ACCGCGGCTT TAAACGCATC


 


801
CGCACGTTTC AACGTTTCAG GGCAAAGCAG TTCCGAACTG AAATTGGGCG


 


851
TACAGCATAC ATTTTAA






This corresponds to the amino acid sequence <SEQ ID 2888; ORF 937.ng>:










g937.pep




1
MKNILLVFVS FVPLCVRTDL PLNIEDIMTD KGKWKLETSL TYLNSENSRA


 


51
ALASPVYIQT GSASFIPVPT EIQENGSNTD MLAGTLGLRY GLTGNTDIYG


 


101
SGSYLWHEER KLDGNGKTRN KRMSDISAGI SHTFLKDGKN PALIAFLEST


 


151
VYEKSRNKAS SGKSWLIGAT TYKAIDPIVL SLTAAYRING SKTLSDDVKY


 


201
KAGNYWMLNP NISFAANDRI SLTGGIQWLG KQPDRIDGKK ESARNTSTYA


 


251
HFGAGFGFTK TAALNASARF NVSGQSSSEL KLGVQHTF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2889>:










m937.seq




1
ATGAAGCGCA TCTTTTTGCC CGCCTTGCCC GCCATCCTGC CTTTATCCAC


 


51
TTATGCCGAC CTGCCCTTGA CGATTGAAGA CATAATGACC GACAAGGGAA


 


101
AATGGAAACT GGAAACTTCC CTTACCTACC TGAACAGCGA AAACAACCGC


 


151
GCCGAACTTG CCGCACCGGT TTACATTCAA ACCGGCGCAA CCTCGTTTAT


 


201
CCCCATTCCG ACCGAAATCC AAgAAAaCGG CAGCAATACC GATATGCTCG


 


251
TCGGCACGCT CGGTTTGCGC TACGGACTGA CCGGGAATAC CGACATTTAC


 


301
GGCAGCGGCA GCTATCTGTG GCACGAAGAA CGCAAACTCG ACGGCAACAG


 


351
CAAAACCCGC AACAAACGGA TGTCCGACGT ATCCCTCGGC ATCAGCCACA


 


401
CTTTCCTTAA AGACGACAAA AACCCCGCCC TAATCAGCTT TCTTGAAAGC


 


451
ACGGTTTACG AAAAATCGCG CAACAAAGCC TCGTCGGGAA AATCCTGGCT


 


501
CATCGGCGCC ACCACCTACA AAGCCATAGA TCCGATTGTC CTTTCCTTAA


 


551
CCGCCGCCTA CCGCATCAAC GGCAGCAAAA CCCTTTCAGA CGGCATCCGC


 


601
TACAAATCGG GCAACTACCT GCTGCTCAAC CCCAACATCT CATTTGCTGC


 


651
CAACGACAGA ATCAGCCTGA CCGGAGGCAT CCAATGGCTG GGCAGGCAGC


 


701
CCGACCGGAC GGACGGCAAA CGGGAATCCT CCAGAAACAC ATCCACCTAC


 


751
GCCCATTTCG GCGCAGGTTT CGGTTTCACC AAAACCACGG CTTTAAACGC


 


801
ATCCGCACGT TTCAACGTTT CAGGGCAAAG CAGTTCCGAA CTGAAATTTG


 


851
GCGTACAGCA TACATTTTAA






This corresponds to the amino acid sequence <SEQ ID 2890; ORF 937>:










m937.pep..




1
MKRIFLPALP AILPLSTYAD LPLTIEDIMT DKGKWKLETS LTYLNSENNR


 


51
AELAAPVYIQ TGATSFIPIP TEIQENGSNT DMLVGTLGLR YGLTGNTDIY


 


101
GSGSYLWHEE RKLDGNSKTR NKRMSDVSLG ISHTFLKDDK NPALISFLES


 


151
TVYEKSRNKA SSGKSWLIGA TTYKAIDPIV LSLTAAYRIN GSKTLSDGIR


 


201
YKSGNYLLLN PNISFAANDR ISLTGGIQWL GRQPDRTDGK RESSRNTSTY


 


251
AHFGAGFGFT KTTALNASAR FNVSGQSSSE LKFGVQHTF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 937 shows 86.9% identity over a 289 aa overlap with a predicted ORF (ORF 937.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2891>:










a937.seq




1
ATGAAGCGCA TCTTTTTGCC CGCCTTGCCC GCCATCCTGC CTTTATCCGC


 


51
TTATGCCGAC CTGCCCTTGA CGATTGAAGA CATAATGACC GACAAGGGCA


 


101
AATGGAAACT GGAAACTTCC CTTACCTACC TGAACAGCGA AAACAACCGC


 


151
GCCGAACTTG CCGCACCGGT TTACATCCAA ACCGGCGCAA CCTCGTTTAT


 


201
CCCCATTCCG ACCGAAATCC AAGAAAACGG CAGCAATACC GATATGCTCG


 


251
TTGGCACGCT CGGTTTGCGC TACGGACTGA CCGGGAATAC CGACATTTAC


 


301
GGCAGCGGCA GCTATCTGTG GCACGAAGAA CGCAAACTCG ACGGCAACGG


 


351
CAAAACCCGA AACAAACGGA TGTCCGACGT ATCCCTCGGC ATCAGCCACA


 


401
CCTTCCTTAA AGACGACAAA AACCCCGCCC TAATCAGCTT TCTTGAAAGC


 


451
ACGGTTTACG AAAAATCGCG CAACAAAGCC TCGTCGGGAA AATCCTGGCT


 


501
CATCGGCGCC ACCACCTACA AAGCCATCGA CCCCGTCGTC CTCTCATTGA


 


551
CCGCTGCCTA CCGTATCAAC GGCAGCAAAA CCCTTTCAAG CAACACCAAA


 


601
TACAAAGCAG GCAATTACTG GATGCTGAAT CCCAATATAT CCTTCGCCGC


 


651
CAACGACAGA ATCAGCCTCA CGGGCGGCAT CCAATGGCTG GGCAAGCAGC


 


701
CCGACCGTCT GGACGGCAAA AAAGAATCCG CAAGAAACAC ATCCACCTAT


 


751
GCCCATTTCG GCGCAGGTTT CGGTTTCACC AAAACCACGG CTTTAAACGC


 


801
ATCCGCACGT TTCAACGTTT CAGGGCAAAG CAGTTCCGAA CTGAAATTTG


 


851
GCGTACAGCA TACGTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2892; ORF 937.a>:










a937.pep




1
MKRIFLPALP AILPLSAYAD LPLTIEDIMT DKGKWKLETS LTYLNSENNR


 


51
AELAAPVYIQ TGATSFIPIP TEIQENGSNT DMLVGTLGLR YGLTGNTDIY


 


101
GSGSYLWHEE RKLDGNGKTR NKRMSDVSLG ISHTFLKDDK NPALISFLES


 


151
TVYEKSRNKA SSGKSWLIGA TTYKAIDPVV LSLTAAYRIN GSKTLSSNTK


 


201
YKAGNYWMLN PNISFAANDR ISLTGGIQWL GKQPDRLDGK KESARNTSTY


 


251
AHFGAGFGFT KTTALNASAR FNVSGQSSSE LKFGVQHTF*






m937/a937 95.2% identity in 289 an overlap





g939.seq not found yet

g939.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2893>:









m939.seq (partial)










1
ATGAAACGAT TGACTTTATT GGCCTTTGTT TTGGCTGCCG GTGCGGTTTC



 


51
CGCCTCTCCC AAAGCAGACG TGGAAAAAGG CAAACAGGTT GCCGCAACGG


 


101
TTTGTGCGGC TTGCCATGCA GCAGACGGTA ACAGCGGCAT TGCGATGTAT


 


151
CCGCGTTTGG CGGCACAGCA TACTGCTTAC ATCTATCATC AAACTATCGG


 


201
CATCCGCGAC GTAAACGCAC CC...






This corresponds to the amino acid sequence <SEQ ID 2894; ORF 939>:









m939.pep (partial)










1
MKRLTLLAFV LAAGAVSASP KADVEKGKQV AATVCAACHA ADGNSGIAMY



 


51
PRLAAQHTAY IYHQTIGIRD VNAP...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2895>:










a939.seq




1
ATGAAACGAT TGACTTTATT GGCCTTTGTT TTGGCTGCCG GTGCGGTTTC


 


51
CGCATCTCCC AAAGCAGACG TGGAAAAAGG CAAACAGGTT GCCGCAACGG


 


101
TTTGTGCGGC TTGCCATGCA GCAGACGGTA ACAGCGGCAT TGCGATGTAT


 


151
CCGCGTTTGG CGGCACAGCA TACTGCTTAC ATCTATCATC AAACCATCGG


 


201
CATCCGCGAC GGTAAACGCA CCCACGGTTC GGCAGCTGTG ATGAAACCGG


 


251
TGGTAATGAA TTTGAGCGAT CAGGATATTT TGAACGTATC CGCATTCTAT


 


301
GCCAAACAGC AGCCCAAATC CGGTGAAGCC AATCCTAAGG AAAATCCCGA


 


351
ATTGGGTGCG AAAATCTATC GCGGCGGTTT GAGCGATAAA AAAGTGCCGG


 


401
CGTGTATGTC CTGCCACGGT CCGAGCGGTG CGGGTATGCC GGGGGGCGGA


 


451
AGCGAAATTC AGGCTTATCC GCGTTTGGGC GGTCAGCATC AGGCATATAT


 


501
TGTTGAACAG ATGAATGCCT ACAAGTCCGG TCAGCGTAAA AATACCATCA


 


551
TGGAAGATAT TGCAAACCGT ATGTCTGAAG AAGATTTGAA AGCGGTCGCC


 


601
AACTTTATCC AAGGTTTGCG TTAA






This corresponds to the amino acid sequence <SEQ ID 2896; ORF 939.a>:










a939.pep




1
MKRLTLLAFV LAAGAVSASP KADVEKGKQV AATVCAACHA ADGNSGIAMY


 


51
PRLAAQHTAY IYHQTIGIRD GKRTHGSAAV MKPVVMNLSD QDILNVSAFY


 


101
AKQQPKSGEA NPKENPELGA KIYRGGLSDK KVPACMSCHG PSGAGMPGGG


 


151
SEIQAYPRLG GQHQAYIVEQ MNAYKSGQRK NTIMEDIANR MSEEDLKAVA


 


201
NFIQGLR*






m939/a939 100.0% identity in 70 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2897>:










g950.seq




1
ATGAACAAAA ATATTGCTGC CGCACTCGCC GGTGCTTTAT CCCTGTCTCT


 


51
GGCCGCCGGC GCCGTTGCCG CCCACAAACC GGCAAGCAAC GCAACAGGCG


 


101
TTCAAAAATC CGCCCAAGGC TCTTGCGGCG CATCCAAATC TGCCGAAGGT


 


151
TCGTGCGGCG CATCCAAATC TGCCGAAGGT TCGTGCGGCG CGGCTGCTTC


 


201
TAAAGCAGGC GAAGGCAAAT GCGGCGAGGG CAAATGCGGT GCAACTGTAA


 


251
AAAAAGCCCA CAAACACACC AAAGCATCTA AAGCCAAAGC CAAATCTGCC


 


301
GAAGGCAAAT GCGGCGAAGG CAAATGCGGT TCTAAATAA






This corresponds to the amino acid sequence <SEQ ID 2898; ORF 950.ng>:










g950.pep




1
MNKNIAAALA GALSLSLAAG AVAAHKPASN ATGVQKSAQG SCGASKSAEG


 


51
SCGASKSAEG SCGAAASKAG EGKCGEGKCG ATVKKAHKHT KASKAKAKSA


 


101
EGKCGEGKCG SK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2899>:










m950.seq




1
ATGAACAAAA ACATTGCTGC CGCTCTCGCC GGTGCTTTAT CCCTGTCTTT


 


51
GGCCGCCGGT GCAGTTGCTG CCAACAAACC GGCAAGCAAC GCAACAGGCG


 


101
TTCATAAATC CGCCCATGGC TCTTGCGGCG CGTCCAAATC TGCCGAAGGT


 


151
TCGTGCGGCG CGGCTGGTTC TAAAGCAGGC GAAGGCAAAT GCGGCGAGGG


 


201
CAAATGCGGT GCGACCGTAA AAAAAACCCA CAAACACACC AAAGCATCTA


 


251
AAGCCAAGGC CAAATCTGCC GAAGGCAAAT GCGGCGAAGG CAAATGCGGT


 


301
TCTAAATAA






This corresponds to the amino acid sequence <SEQ ID 2900; ORF 950>:










m950.pep




1
MNKNIAAALA GALSLSLAAG AVAANKPASN ATGVHKSAHG SCGASKSAEG


 


51
SCGAAGSKAG EGKCGEGKCG ATVKKTHKHT KASKAKAKSA EGKCGEGKCG


 


101
SK






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 950 shows 86.6% identity over a 112 aa overlap with a predicted ORF (ORF 950) from N. gonorrhoeae 

m950/g950 86.6% identity in 112 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2901>:










a950.seq




1
ATGAACAAAA ACATTGCTGC CGCACTCGCC GGTGCTTTAT CCCTGTCTTT


 


51
GGCCGCCGGT GCAGTTGCTG CCAACAAACC GGCAAGCAAC GCAACAGGCG


 


101
TTCATAAATC CGCCCATGGC TCTTGCGGCG CGTCCAAATC TGCCGAAGGT


 


151
TCGTGCGGCG CGGCTGGTTC TAAAGCAGGC GAAGGCAAAT GCGGCGAGGG


 


201
CAAATGCGGT GCGACCGTAA AAAAAACCCA CAAACACACC AAAGCATCTA


 


251
AAGCCAAGGC CAAATCTGCC GAAGGCAAAT GCGGCGAAGG CAAATGCGGT


 


301
TCTAAATAA






This corresponds to the amino acid sequence <SEQ ID 2902; ORF 950.a>:










a950.pep




1
MNKNIAAALA GALSLSLAAG AVAANKPASN ATGVHKSAHG SCGASKSAEG


 


51
SCGAAGSKAG EGKCGEGKCG ATVKKTHKHT KASKAKAKSA EGKCGEGKCG


 


101
SK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 950 shows 100.0% identity over a 102 aa overlap with a predicted ORF (ORF 950) from N. meningitidis 

a950/m950 100.0% identity in 102 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2903>:










g951.seq




1
ATGATTATGT TACCCGCCCG TTTCACTATT TTATCTGTCC TCGCAGCAGC


 


51
CCTGCTTGCC GGACAGGCGT ATGCTGCCGG CGCGGCGGAT GTGGAGCTGC


 


101
CGAAGGAAGT CGGAAAGGTT TTAAGGAAAC ATCGGCGTTA CAGCGAGGAA


 


151
GAAATCAAAA ACGAACGCGC ACGGCTTGCG GCAGTGGGCG AACGGGTCAA


 


201
CAGGGTGTTT ACGCTGTTGG GCGGTGAAAC GGCTTTGCAG AAAGGGCAGG


 


251
CGGGAACGGC TCTGGCAACC TATATGCTGA TGTTGGAACG CACAAAATCC


 


301
CCCGAAGTCG CCGAACGCGC CTTGGAAATG GCCGTGTCGC TGAACGCGTT


 


351
TGAACAGGCG GAAATGATTT ATCAGAAATG GCGGCAGATC GAGCCTATAC


 


401
CGGGTGAGGC GCAAAAACGG GCGGGGTGGC TGCGGAACGT ATTGAGGGAA


 


451
GGGGGAAATC AGCATCTGGA CGGGTTGGAA GAGGTGCTGG CGCAATCGGA


 


501
CGATGTGCAA AAACGCAGGA TATTTTTGCT GCTGGTGCAA GCCGCCGTGC


 


551
AGCAGGGTGG GGTGGCTCAA AAAGCATCGA AAGCGGTTCG CCGTGCGGCG


 


601
TTGAAGTATG AACATCTGCC CGAAGCGGCG GTTGCCGATG CGGTGTTCGG


 


651
CGTACAGGGA CGCGAAAAGG AAAAGGCAAT CGAAGCTTTG CAGCGTTTGG


 


701
CGAAGCTCGA TACGGAAATA TTGCCCCCCA CTTTAATGAC GTTGCGTCTG


 


751
ACTGCACGCA AATATCCCGA AATACTCGAC GGCTTTTTCG AGCAGACAGA


 


801
CACCCAAAAC CTTTCGGCCG TCTGGCAGGA AATGGAAATT ATGAATCTGG


 


851
TTTCCCTGCG TAAGCCGGAT GATGCCTATG CGCGTTTGAA CGTGCTGTTG


 


901
GAACACAACC CGAATGCAAA CCTGTATATT CAGGCGGCGA TATTGGCGGC


 


951
AAACCGAAAA GAAGGTGCGT CCGTTATCGA CGGCTACGCC GAAAAGGCAT


 


1001
ACGGCAGGGG GACGGGGGAA CAGCGGGGCA GGGCGGCAAT GACGGCGGCG


 


1051
ATGATATATG CCGACCGCAG GGATTACGCC AAAGTCAGGC AGTGGTTGAA


 


1101
AAAAGTGTCC GCGCCGGAAT ACCTGTTCGA CAAAGGCGTG CTGGCGGCTG


 


1151
CGGCGGCTGC CGAATTGGAC GGAGGCCGGG CGGCTTTGCG GCAGATCGGC


 


1201
AGGGTGCGGA AACTTCCCGA ACAGCAGGGG CGGTATTTTA CGGCAGACAA


 


1251
TTTGTCCAAA ATACAGATGC TCGCCCTGTC GAAGCTGCCC GACAAACGGG


 


1301
AAGCCCTGAT CGGGCTGAAC AACATCATCG CCAAACTTTC GGCGGCGGGA


 


1351
AGCACGGAAC CTTTGGCGGA AGCATTGGCA CAGCGTTCCA TTATTTACGA


 


1401
ACAGTTCGGC AAACGGGGAA AAATGATTGC CGACCTTGAA ACCGCGCTCA


 


1451
AACTTACGCC CGATAATGCA CAAATTATGA ATAATCTGGG CTACAGCCTG


 


1501
CTTTCCGATT CCAAACGTTT GGACGAGGGT TTCGCCCTGC TTCAGACGGC


 


1551
ATACCAAATC AACCCGGACG ATACCGCCGT TAACGACAGC ATAGGCTGGG


 


1601
CGTATTACCT GAAAGGCGAC GCGGAAAGCG CGCTGCCGTA TCTGCGGTAT


 


1651
TCGTTTGAAA ACGACCCCGA GCCCGAAGTT GCCGCCCATT TGGGCGAAGT


 


1701
GTTGTGGGCA TTGGGCGAAC GCGATCAGGC GGTTGACGTA TGGACGCAGG


 


1751
CGGCACACCT TAGGGGAGAC AAGAAAATAT GGCGGGAGAC GCTCAAACGC


 


1801
TACGGAATCG CCTTGCCCGA GCCTTCCCGA AAACCCCGGA AATAA






This corresponds to the amino acid sequence <SEQ ID 2904; ORF 951.ng>:










g951.pep




1
MIMLPARFTI LSVLAAALLA GQAYAAGAAD VELPKEVGKV LRKHRRYSEE


 


51
EIKNERARLA AVGERVNRVF TLLGGETALQ KGQAGTALAT YMLMLERTKS


 


101
PEVAERALEM AVSLNAFEQA EMIYQKWRQI EPIPGEAQKR AGWLRNVLRE


 


151
GGNQHLDGLE EVLAQSDDVQ KRRIFLLLVQ AAVQQGGVAQ KASKAVRRAA


 


201
LKYEHLPEAA VADAVFGVQG REKEKAIEAL QRLAKLDTEI LPPTLMTLRL


 


251
TARKYPEILD GFFEQTDTQN LSAVWQEMEI MNLVSLRKPD DAYARLNVLL


 


301
EHNPNANLYI QAAILAANRK EGASVIDGYA EKAYGRGTGE QRGRAAMTAA


 


351
MIYADRRDYA KVRQWLKKVS APEYLFDKGV LAAAAAAELD GGRAALRQIG


 


401
RVRKLPEQQG RYFTADNLSK IQMLALSKLP DKREALIGLN NIIAKLSAAG


 


451
STEPLAEALA QRSIIYEQFG KRGKMIADLE TALKLTPDNA QIMNNLGYSL


 


501
LSDSKRLDEG FALLQTAYQI NPDDTAVNDS IGWAYYLKGD AESALPYLRY


 


551
SFENDPEPEV AAHLGEVLWA LGERDQAVDV WTQAAHLRGD KKIWRETLKR


 


601
YGIALPEPSR KPRK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2905>:










m951.seq




1
ATGATTATGT TACCTAACCG TTTCAAAATG TTAACTGTGT TGACGGCAAC


 


51
CTTGATTGCC GGACAGGTAT CTGCCGCCGG AGGCGGTGCG GGGGATATGA


 


101
AACAGCCGAA GGAAGTCGGA AAGGTTTTCA GAAAGCAGCA GCGTTACAGC


 


151
GAGGAAGAAA TCAAAAACGA ACGCGCACGG CTTGCGGCAG TGGGCGAGCG


 


201
GGTTAATCAG ATATTTACGT TGCTGGGAGG GGAAACCGCC TTGCAAAAGG


 


251
GGCAGGCGGG AACGGCTCTG GCAACCTATA TGCTGATGTT GGAACGCACA


 


301
AAATCCCCCG AAGTCGCCGA ACGCGCCTTG GAAATGGCCG TGTCGCTGAA


 


351
CGCGTTTGAA CAGGCGGAAA TGATTTATCA GAAATGGCGG CAGATTGAGC


 


401
CTATACCGGG TAAGGCGCAA AAACGGGCGG GGTGGCTGCG GAACGTGCTG


 


451
AGGGAAAGAG GAAATCAGCA TCTGGACGGA CTGGAAGAAG TGCTGGCTCA


 


501
GGCGGACGAA GGACAGAACC GCAGGGTGTT TTTATTGTTG GCACAAGCCG


 


551
CCGTGCAACA GGACGGGTTG GCGCAAAAAG CATCGAAAGC GGTTCGCCGC


 


601
GCGGCGTTGA AATATGAACA TCTGCCCGAA GCGGCGGTTG CCGATGTGGT


 


651
GTTCAGCGTA CAGGGACGCG AAAAGGAAAA GGCAATCGGA GCTTTGCAGC


 


701
GTTTGGCGAA GCTCGATACG GAAATATTGC CCCCCACTTT AATGACGTTG


 


751
CGTCTGACTG CACGCAAATA TCCCGAAATA CTCGACGGCT TTTTCGAGCA


 


801
GACAGACACC CAAAACCTTT CGGCCGTCTG GCAGGAAATG GAAATTATGA


 


851
ATCTGGTTTC CCTGCACAGG CTGGATGATG CCTATGCGCG TTTGAACGTG


 


901
CTGTTGGAAC GCAATCCGAA TGCAGACCTG TATATTCAGG CAGCGATATT


 


951
GGCGGCAAAC CGAAAAGAAG GTGCTTCCGT TATCGACGGC TACGCCGAAA


 


1001
AGGCATACGG CAGGGGGACG GAGGAACAGC GGAGCAGGGC GGCGCTAACG


 


1051
GCGGCGATGA TGTATGCCGA CCGCAGGGAT TACGCCAAAG TCAGGCAGTG


 


1101
GCTGAAAAAA GTATCCGCGC CGGAATACCT GTTCGACAAA GGTGTGCTGG


 


1151
CGGCTGCGGC GGCTGTCGAG TTGGACGGCG GCAGGGCGGC TTTGCGGCAG


 


1201
ATCGGCAGGG TGCGGAAACT TCCCGAACAG CAGGGGCGGT ATTTTACGGC


 


1251
AGACAATTTG TCCAAAATAC AGATGCTCGC CCTGTCGAAG CTGCCCGATA


 


1301
AACGGGAGGC TTTGAGGGGG TTGGACAAGA TTATCGAAAA ACCGCCTGCC


 


1351
GGCAGTAATA CAGAGTTACA GGCAGAGGCA TTGGTACAGC GGTCAGTTGT


 


1401
TTACGATCGG CTTGGCAAGC GGAAAAAAAT GATTTCAGAT CTTGAAAGGG


 


1451
CGTTCAGGCT TGCACCCGAT AACGCTCAGA TTATGAATAA TCTGGGCTAC


 


1501
AGCCTGCTGA CCGATTCCAA ACGTTTGGAC GAAGGTTTCG CCCTGCTTCA


 


1551
GACGGCATAC CAAATCAACC CGGACGATAC CGCTGTCAAC GACAGCATAG


 


1601
GCTGGGCGTA TTACCTGAAA GGCGACGCGG AAAGCGCGCT GCCGTATCTG


 


1651
CGGTATTCGT TTGAAAACGA CCCCGAGCCC GAAGTTGCCG CCCATTTGGG


 


1701
CGAAGTGTTG TGGGCATTGG GCGAACGCGA TCAGGCGGTT GACGTATGGA


 


1751
CGCAGGCGGC ACACCTTACG GGAGACAAGA AAATATGGCG GGAAACGCTC


 


1801
AAACGTCACG GCATCGCATT GCCCCAACCT TCCCGAAAAC CTCGGAAATA


 


1851
A






This corresponds to the amino acid sequence <SEQ ID 2906; ORF 791>:










m951.pep




1
MIMLPNRFKM LTVLTATLIA GQVSAAGGGA GDMKQPKEVG KVFRKQQRYS


 


51
EEEIKNERAR LAAVGERVNQ IFTLLGGETA LQKGQAGTAL ATYMLMLERT


 


101
KSPEVAERAL EMAVSLNAFE QAEMIYQKWR QIEPIPGKAQ KRAGWLRNVL


 


151
RERGNQHLDG LEEVLAQADE GQNRRVFLLL AQAAVQQDGL AQKASKAVRR


 


201
AALKYEHLPE AAVADVVFSV QGREKEKAIG ALQRLAKLDT EILPPTLMTL


 


251
RLTARKYPEI LDGFFEQTDT QNLSAVWQEM EIMNLVSLHR LDDAYARLNV


 


301
LLERNPNADL YIQAAILAAN RKEGASVIDG YAEKAYGRGT EEQRSRAALT


 


351
AAMMYADRRD YAKVRQWLKK VSAPEYLFDK GVLAAAAAVE LDGGRAALRQ


 


401
IGRVRKLPEQ QGRYFTADNL SKIQMLALSK LPDKREALRG LDKIIEKPPA


 


451
GSNTELQAEA LVQRSVVYDR LGKRKKMISD LERAFRLAPD NAQIMNNLGY


 


501
SLLTDSKRLD EGFALLQTAY QINPDDTAVN DSIGWAYYLK GDAESALPYL


 


551
RYSFENDPEP EVAAHLGEVL WALGERDQAV DVWTQAAHLT GDKKIWRETL


 


601
KRHGIALPQP SRKPRK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 951 shows 88.6% identity over a 616 aa overlap with a predicted ORF (ORF 951) from N. gonorrhoeae 

m951/g951 88.6% identity in 616 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2907>:










a951.seq




1
ATGTTACCCG CCCGTTTCAC CATTTTATCT GTGCTCGCGG CAGCCCTGCT


 


51
TGCCGGGCAG GCGTATGCCG CCGGCGCGGC GGATGCGAAG CCGCCGAAGG


 


101
AAGTCGGAAA GGTTTTCAGA AAGCAGCAGC GTTACAGCGA GGAAGAAATC


 


151
AAAAACGAAC GCGCACGGCT TGCGGCAGTG GGCGAGCGGG TTAATCAGAT


 


201
ATTTACGTTG CTGGGAGGGG AAACCGCCTT GCAAAAGGGG CAGGCGGGAA


 


251
CGGCTCTGGC AACCTATATG CTGATGTTGG AACGCACAAA ATCCCCCGAA


 


301
GTCGCCGAAC GCGCCTTGGA AATGGCCGTG TCGCTGAACG CGTTTGAACA


 


351
GGCGGAAATG ATTTATCAGA AATGGCGGCA GATTGAGCCT ATACCGGGTA


 


401
AGGCGCAAAA ACGGGCGGGG TGGCTGCGGA ACGTGCTGAG GGAAAGAGGA


 


451
AATCAGCATC TAGACGGACT GGAAGAAGTG CTGGCTCAGG CGGACGAAGG


 


501
ACAGAACCGC AGGGTGTTTT TATTGTTGGC ACAAGCCGCC GTGCAACAGG


 


551
ACGGGTTGGC GCAAAAAGCA TCGAAAGCGG TTCGCCGCGC GGCGTTGAGA


 


601
TATGAACATC TGCCCGAAGC GGCGGTTGCC GATGTGGTGT TCAGCGTACA


 


651
GGGACGCGAA AAGGAAAAGG CAATCGGAGC TTTGCAGCGT TTGGCGAAGC


 


701
TCGATACGGA AATATTGCCC CCCACTTTAA TGACGTTGCG TCTGACTGCA


 


751
CGCAAATATC CCGAAATACT CGACGGCTTT TTCGAGCAGA CAGACACCCA


 


801
AAACCTTTCG GCCGTCTGGC AGGAAATGGA AATTATGAAT CTGGTTTCCC


 


851
TGCACAGGCT GGATGATGCC TATGCGCGTT TGAACGTGCT GTTGGAACGC


 


901
AATCCGAATG CAGACCTGTA TATTCAGGCA GCGATATTGG CGGCAAACCG


 


951
AAAAGAAGGT GCTTCCGTTA TCGACGGCTA CGCCGAAAAG GCATACGGCA


 


1001
GGGGGACGGG GGAACAGCGG GGCAGGGCGG CAATGACGGC GGCGATGATA


 


1051
TATGCCGACC GAAGGGATTA CACCAAAGTC AGGCAGTGGT TGAAAAAAGT


 


1101
GTCCGCGCCG GAATACCTGT TCGACAAAGG TGTGCTGGCG GCTGCGGCGG


 


1151
CTGTCGAGTT GGACGGCGGC AGGGCGGCTT TGCGGCAGAT CGGCAGGGTG


 


1201
CGGAAACTTC CCGAACAGCA GGGGCGGTAT TTTACGGCAG ACAATTTGTC


 


1251
CAAAATACAG ATGTTCGCCC TGTCGAAGCT GCCCGACAAA CGGGAGGCTT


 


1301
TGAGGGGGTT GGACAAGATT ATCGAAAAAC CGCCTGCCGG CAGTAATACA


 


1351
GAGTTACAGG CAGAGGCATT GGTACAGCGG TCAGTTGTTT ACGATCGGCT


 


1401
TGGCAAGCGG AAAAAAATGA TTTCAGATCT TGAAAGGGCG TTCAGGCTTG


 


1451
CACCCGATAA CGCTCAGATT ATGAATAATC TGGGCTACAG CCTGCTTTCC


 


1501
GATTCCAAAC GTTTGGACGA AGGCTTCGCC CTGCTTCAGA CGGCATACCA


 


1551
AATCAACCCG GACGATACCG CTGTCAACGA CAGCATAGGC TGGGCGTATT


 


1601
ACCTGAAAGG CGACGCGGAA AGCGCGCTGC CGTATCTGCG GTATTCGTTT


 


1651
GAAAACGACC CCGAGCCCGA AGTTGCCGCC CATTTGGGCG AAGTGTTGTG


 


1701
GGCATTGGGC GAACGCGATC AGGCGGTTGA CGTATGGACG CAGGCGGCAC


 


1751
ACCTTACGGG AGACAAGAAA ATATGGCGGG AAACGCTCAA ACGTCACGGC


 


1801
ATCGCATTGC CCCAACCTTC CCGAAAACCT CGGAAATAA






This corresponds to the amino acid sequence <SEQ ID 2908; ORF 951.a>:










a951.pep




1
MLPARFTILS VLAAALLAGQ AYAAGAADAK PPKEVGKVFR KQQRYSEEEI


 


51
KNERARLAAV GERVNQIFTL LGGETALQKG QAGTALATYM LMLERTKSPE


 


101
VAERALEMAV SLNAFEQAEM IYQKWRQIEP IPGKAQKRAG WLRNVLRERG


 


151
NQHLDGLEEV LAQADEGQNR RVFLLLAQAA VQQDGLAQKA SKAVRRAALR


 


201
YEHLPEAAVA DVVFSVQGRE KEKAIGALQR LAKLDTEILP PTLMTLRLTA


 


251
RKYPEILDGF FEQTDTQNLS AVWQEMEIMN LVSLHRLDDA YARLNVLLER


 


301
NPNADLYIQA AILAANRKEG ASVIDGYAEK AYGRGTGEQR GRAAMTAAMI


 


351
YADRRDYTKV RQWLKKVSAP EYLFDKGVLA AAAAVELDGG RAALRQIGRV


 


401
RKLPEQQGRY FTADNLSKIQ MFALSKLPDK REALRGLDKI IEKPPAGSNT


 


451
ELQAEALVQR SVVYDRLGKR KKMISDLERA FRLAPDNAQI MNNLGYSLLS


 


501
DSKRLDEGFA LLQTAYQINP DDTAVNDSIG WAYYLKGDAE SALPYLRYSF


 


551
ENDPEPEVAA HLGEVLWALG ERDQAVDVWT QAAHLTGDKK IWRETLKRHG


 


600
IALPQPSRKP RK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 951 shows 96.4% identity over a 614 aa overlap with a predicted ORF (ORF 951) from N. meningitidis 

a951/m951 96.4% identity in 614 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2909>:









g952.seq (partial)










1
..TTGTCTTATC GTTTGAATGC TGCACCGATG TTTAACGATA ATCCTGTTGT



 


51
  TTACGGAAAA ATCAAATTGC AGAGTTGGAA AGCGCGGCGG GATTTCAATA


 


101
  TTGTAAAGCA GGATTTGGAT TTTTCCTGCG GGGCGGCTTC GGTGGCGACG


 


151
  CTTTTGAACA ATTTTTACGG GCAAAAGCTG ACGGAAGAAG AAGTGTTGGA


 


201
  AAAACTGGGT AAGGAACAGA TGCGCGCGTC GTTTGAGGAT ATGCGGCGCA


 


251
  TTATGCCCGA TTTGGGTTTT GAGGCGAAAG GCTATGCCCT GTCTTTCGAA


 


301
  CAGCTCGCGC AGTTGAAAAT CCCCGTCATC GTGTATCTGA AATACCGCAA


 


351
  AGACGACCAT TTTTCGGTAT TGCGCGGAGT GGATGGCAAT ACGGTTTTGC


 


401
  TTGCCGACCC GTCGCCGGGT CATGTTTCGA TGAGCAGGGC GCAGTTTTTG


 


451
  GAGGCTTGGC AAACCCGTGA GGGAAATTTG GCAGGCAAAA TTTTGGCGGT


 


501
  CGTGCCGAAA AAAGCGGAGG CGATTTCAAA TAAATTGTTT TTCACACATC


 


551
  ATCCCAAGCG GCAGACGGAG TTTGCAGTCG GACAGGTAAA ATGGTGGCGT


 


601
  GCTTATTGA






This corresponds to the amino acid sequence <SEQ ID 2910; ORF 952.ng>:









g952.pep (partial)










1
..LSYRLNAAPM FNDNPVVYGK IKLQSWKARR DFNIVKQDLD FSCGAASVAT



 


51
  LLNNFYGQKL TEEEVLEKLG KEQMRASFED MRRIMPDLGF EAKGYALSFE


 


101
  QLAQLKIPVI VYLKYRKDDH FSVLRGVDGN TVLLADPSPG HVSMSRAQFL


 


151
  EAWQTREGNL AGKILAVVPK KAEAISNKLF FTHHPKRQTE FAVGQVKWWR


 


201
  AY*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2911>:










m952.seq




1
ATGATGAAGT TCAAATATGT TTTTCTGTTG GCGTGTGTTG TCGTTTCTTT


 


51
ATCTTATCGT TTGAATGCTG CACCGATGTT TAACGATAAT CCTGTTGTTT


 


101
ACGGAAAAAT CAAAGTGCAG AGTTGGAAAG CGCGGCGGGA TTTCAATATT


 


151
GTAAAGCAGG ATTTGGATTT TTCCTGTGGG GCGGCTTCGG TGGCGACGCT


 


201
TTTGAACAAT TTTTACGGGC AAACGCTGAC GGAAGAAGAA GTGTTGAAAA


 


251
AGCTGGATAA GGAGCAGATG CGCGCGTCGT TTGAGGATAT GCGGCGCATT


 


301
ATGCCTGATT TGGGTTTTGA GGCGAAGGGC TATGCCCTGT CTTTCGAGCA


 


351
GCTCGCGCAG TTGAAAATCC CCGTCATCGT GTATCTGAAA TACCGCAAAG


 


401
ACGACCATTT TTCGGTATTG CGCGGTATAG ACGGCAATAC GGTTTTGCTT


 


451
GCCGACCCGT CGCTGGGGCA TGTTTCAATG AGCAGGGCGC AGTTTTTGGA


 


501
TGCTTGGCAA ACCCGTGAGG GAAATTTGGC AGGTAAGATT TTGGCTGTCA


 


551
TACCGAAAAA AGCCGAGACA ATTTCAAATA AATTGTTTTT CACACAACAC


 


601
CCAAAACGGC AGACGGAGTT TACAGTCGGA CAAATCAGGC AAGCACGTGC


 


651
AGAGTAA






This corresponds to the amino acid sequence <SEQ ID 2912; ORF 952>:










m952.pep




1
MMKFKYVFLL ACVVVSLSYR LNAAPMFNDN PVVYGKIKVQ SWKARRDFNI


 


51
VKQDLDFSCG AASVATLLNN FYGQTLTEEE VLKKLDKEQM RASFEDMRRI


 


101
MPDLGFEAKG YALSFEQLAQ LKIPVIVYLK YRKDDHFSVL RGIDGNTVLL


 


151
ADPSLGHVSM SRAQFLDAWQ TREGNLAGKI LAVIPKKAET ISNKLFFTQH


 


201
PKRQTEFTVG QIRQARAE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 952 shows 92.5% identity over a 201 aa overlap with a predicted ORF (ORF 952) from N. gonorrhoeae 

g952/m952; 92.5% identity in 201 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2913>:










a952.seq




1
ATGATGAAGT TCAAATATGT TTTTCTGTTG GCGTGTGTTG TCGTTTCTTT


 


51
ATCTTATCGT TTGAATGCTG CACCGATGTT TAACGATAAT CCTGTTGTTT


 


101
ACGGAAAAAT CAAAGTGCAG AGTTGGAAAG AAAGGCGGGA TTTCAATATT


 


151
GTAAAGCAGG ATTTGGATTT TTCCTGCGGG GCGGCTTCGG TGGCGACGCT


 


201
TTTGAACAAT TTTTACGGGC AAACGCTGAC GGAAGAAGAA GTGTTGAAAA


 


251
AGCTGGATAA GGAGCAGATG CGCGCGTCGT TTGAGGATAT GCGGCGCATT


 


301
ATGCCAGATT TGGGTTTTGA AGCGAAAGGC TATGCCCTGT CTTTCGAGCA


 


351
GCTCGCACAG TTGAAAATCC CCGTCATCGT GTATCTGAAA TACCGCAAGG


 


401
ATGATCATTT CTCGGTATTG CGCGGGATAG ACGGCAATAC GGTTTTGCTT


 


451
GCCGACCCGT CGCTGGGTCA TGTTTCAATG AGCAGGGCGC AGTTTTNGGA


 


501
TGCTTGGCAA ACCCGTGAGG GAAATTTGGC AGGTAAGATT TTGGCGGTCG


 


551
TGCCGAAAAA AGCCGAGACA ATTTCAAATA AATTGTTTTT CACACATCAT


 


601
CCCAAGCGGC AGACGGAGTT TGCAGTCGGA CAAATCAGGC AAGCACGTGC


 


651
AGAGTAA






This corresponds to the amino acid sequence <SEQ ID 2914; ORF 952.a>:










a952.pep




1
MMKFKYVFLL ACVVVSLSYR LNAAPMFNDN PVVYGKIKVQ SWKERRDFNI


 


51
VKQDLDFSCG AASVATLLNN FYGQTLTEEE VLKKLDKEQM RASFEDMRRI


 


101
MPDLGFEAKG YALSFEQLAQ LKIPVIVYLK YRKDDHFSVL RGIDGNTVLL


 


151
ADPSLGHVSM SRAQFXDAWQ TREGNLAGKI LAVVPKKAET ISNKLFFTHH


 


201
PKRQTEFAVG QIRQARAE*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 952 shows 97.7% identity over a 218 aa overlap with a predicted ORF (ORF 952) from N. meningitidis 

a952/m952 97.7% identity in 218 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2915>:










g953.seq




1
ATGAAAAAAA TCATCTTCGC CGCGCTCGCA GCGGCAGCCG TCGGCACTGC


 


51
CTCCGCCACC TACAAAGTGG ACGAATATCA CGCCAACGTC CGTTTCGCCA


 


101
TCGACCACTT CAACACCAGC ACCAACGTCG GCGGTTTTTA CGGTCTGACC


 


151
GGTTCCGTCG AGTTCGATCA AGCAAAACGC GACGGCAAAA TCGACATCAC


 


201
CATTCCCGTC GCCAACCTGC AAAGCGGTTC GCAACCCTTC ACCGGCCACC


 


251
TGAAATCCGC CGACATCTTC GATGCCGCTC AATATCCGGA CATCCGCTTC


 


301
GTTTCCACCA AATTCAACTT CAACGGCAAA AAACTTGTTT CCGTTGACGG


 


351
CAACCTGACC ATGCGCGGCA AAACCGCCCC CGTCAAACTC AAAGCCGAAA


 


401
AATTCAACTG CTACCAAAGC CCGATGGCGG AAACCGAAGT TTGCGGCGGC


 


451
GACTTCAGCA CCACCATCGA CCGCACCAAA TGGGGCGTGG ACTACCTCGT


 


501
TAACGCCGGT ATGACCAAAA ACGTCCGCAT CGACATCCAA ATCGAAGCTG


 


551
CAAAACAATA A






This corresponds to the amino acid sequence <SEQ ID 2916; ORF 953.ng>:










g953.pep




1
MKKIIFAALA AAAVGTASAT YKVDEYHANV RFAIDHFNTS TNVGGFYGLT


 


51
GSVEFDQAKR DGKIDITIPV ANLQSGSQPF TGHLKSADIF DAAQYPDIRF


 


101
VSTKFNFNGK KLVSVDGNLT MRGKTAPVKL KAEKFNCYQS PMAETEVCGG


 


151
DFSTTIDRTK WGVDYLVNAG MTKNVRIDIQ IEAAKQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2917>:










m953.seq




1
ATGAAAAAAA TCATCTTCGC CGCACTCGCA GCCGCCGCCA TCAGTACTGC


 


51
CTCCGCCGCC ACCTACAAAG TGGACGAATA TCACGCCAAC GCCCGTTTCG


 


101
CCATCGACCA TTTCAACACC AGCACCAACG TCGGCGGTTT TTACGGTCTG


 


151
ACCGGTTCCG TCGAGTTCGA CCAAGCAAAA CGCGACGGTA AAATCGACAT


 


201
CACCATCCCC ATTGCCAACC TGCAAAGCGG TTCGCAACAC TTTACCGACC


 


251
ACCTGAAATC AGCCGACATC TTCGATGCCG CCCAATATCC GGACATCCGC


 


301
TTTGTTTCCA CCAAATTCAA CTTCAACGGC AAAAAACTGG TTTCCGTTGA


 


351
CGGCAACCTG ACCATGCACG GCAAAACCGC CCCCGTCAAA CTCAAAGCCG


 


401
AAAAATTCAA CTGCTACCAA AGCCCGATGG AGAAAACCGA AGTTTGTGGC


 


451
GGCGACTTCA GCACCACCAT CGACCGCACC AAATGGGGCA TGGACTACCT


 


501
CGTTAACGTT GGTATGACCA AAAGCGTCCG CATCGACATC CAAATCGAGG


 


551
CAGCCAAACA ATAA






This corresponds to the amino acid sequence <SEQ ID 2918; ORF 953>:










m953.pep




1
MKKIIFAALA AAAISTASAA TYKVDEYHAN ARFAIDHFNT STNVGGFYGL


 


51
TGSVEFDQAK RDGKIDITIP IANLQSGSQH FTDHLKSADI FDAAQYPDIR


 


101
FVSTKFNFNG KKLVSVDGNL TMHGKTAPVK LKAEKFNCYQ SPMEKTEVCG


 


151
GDFSTTIDRT KWGMDYLVNV GMTKSVRIDI QIEAAKQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 953 shows 93.0% identity over a 187 aa overlap with a predicted ORF (ORF 953) from N. gonorrhoeae 

m953/g953 93.0% identity in 187 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2919>:










a953.seq




1
ATGAAAAAAA TCATCATCGC CGCGCTCGCA GCAGCCGCCA TCGGCACTGC


 


51
CTCCGCCGCC ACCTACAAAG TGGACGAATA TCACGCCAAC GCCCGTTTCT


 


101
CTATCGACCA TTTCAACACC AGCACCAACG TCGGCGGTTT TTACGGTCTG


 


151
ACCGGTTCCG TTGAGTTCGA CCAAGCAAAA CGCGACGGTA AAATCGACAT


 


201
CACCATCCCC GTTGCCAACC TGCAAAGCGG TTCGCAACAC TTTACCGACC


 


251
ACCTGAAATC AGCCGACATC TTCGATGCCG CCCAATATCC GGACATCCGC


 


301
TTTGTTTCCA CCAAATTCAA CTTCAACGGC AAAAAACTGG TTTCCGTTGA


 


351
CGGCAACCTG ACCATGCACG GCAAAACCGC CCCCGTCAAA CTCAAAGCCG


 


401
AAAAATTCAA CTGCTACCAA AGCCCGATGT TGAAAACCGA AGTTTGCGGC


 


451
GGCGACTTCA GCACCACCAT CGACCGCACC AAATGGGGCA TGGACTACCT


 


501
CGTTAACGTT GGTATGACCA AAAGCGTCCG CATCGACATC CAAATCGAGG


 


551
CAGCCAAACA ATAA






This corresponds to the amino acid sequence <SEQ ID 2920; ORF 953.a>:










a953.pep




1
MKKIIIAALA AAAIGTASAA TYKVDEYHAN ARFSIDHFNT STNVGGFYGL


 


51
TGSVEFDQAK RDGKIDITIP VANLQSGSQH FTDHLKSADI FDAAQYPDIR


 


101
FVSTKFNFNG KKLVSVDGNL TMHGKTAPVK LKAEKFNCYQ SPMLKTEVCG


 


151
GDFSTTIDRT KWGMDYLVNV GMTKSVRIDI QIEAAKQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 953 shows 97.3% identity over a 187 aa overlap with a predicted ORF (ORF 953) from N. meningitidis 

a953/m953 97.3% identity in 187 aa overlap





g954.seq not found yet

g954.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2921>:










m954.seq




1
ATGAAAAAGT TTTATTTTGT GCTGCTGGCG TTGGGTTTGG CAGCGTGTGG


 


51
GCAAGAACAA TCGCAGAAAG CTGATGCGGA GCAGTATTTT TTTGCCAATA


 


101
AATATCAATT TGCAGATGAG AAACAGGCTT TTTATTTTGA ACGCGCCGCC


 


151
CGTTTCCGTG TATTGCAACA AGGCCTTGGC GGGGATTTTG AGAGGTTTTT


 


201
AAAAGGAGAA ATACCTAATC AAGAAAATCT TGCAAAGTAT CGTGAAAATA


 


251
TTACTCAAGC AGTCGCTTAT TATGCGGACA CGAATGGAGA TGATGACCCA


 


301
TACCGCGTCT GCAAACAGGC TGCGCAAGAT GCAGAAATCC TGATGAAGAG


 


351
TATGGTAACA AGCGGTGGAG GCGGTACAAC TGATTTAGAT AAGGAAAGTT


 


401
ATCAAAATTA CCGAAAATCA ATGCAAGAAT GCCGTAAAAC AATAACGGAA


 


451
GCTGAAGCCA ATTTGCCGAA AAAATAA






This corresponds to the amino acid sequence <SEQ ID 2922; ORF 954>:










m954.pep




1
MKKFYFVLLA LGLAACGQEQ SQKADAEQYF FANKYQFADE KQAFYFERAA


 


51
RFRVLQQGLG GDFERFLKGE IPNQENLAKY RENITQAVAY YADTNGDDDP


 


101
YRVCKQAAQD AEILMKSMVT SGGGGTTDLD KESYQNYRKS MQECRKTITE


 


151
AEANLPKK*






a954.seq not found yet

a954.pep not found yet

The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2923>:









g957.seq (partial)










1
ATGTTTAAAA AATTCAAACC GGTACTGTTG TCATTTTTTG CACTTGTATT



 


51
TGCCTTTTGG CTGGGAACAG GTATTGCCTA TGAGATTAAT CCGCGTTGGT


 


101
TTTTGAGCGA TACGGCAACT GAAGTACCTG AAAATCCGAA TGCTTTTGTG


 


151
GCGAAACTTG CCCGCCTGTT CCGAAATGCC GACAGGGCGG TTGTCATCGT


 


201
GAAGGAATCG ATGAGGACGG AGGAAAGCCT TGCCGGAGCT GTGGATGACG


 


251
GTCCGTTGCA GTCGGAGAAG GATTATCTCG CGCTCGCTAT CCGGCTCAGT


 


301
CGTTTGAAAG AAAAGGCGAA ATGGTTTCAC GTAACGGAGC AGGAACATGG


 


351
GGAAGAGGTT TGGCTGGATT ACTATATCGG CGAGGGCGGT TTGGTTGCGG


 


401
TTTCGCTTTC GCAACGCTCG CCGGAAGCGT TTGTTAATGC CGAATATCTG


 


451
TATCGGAACG ATCGTCCGTT TTCTGTAAAT GTGTACGGCG GAACGGCTCA


 


501
CGGGGAAAAT TATGAAACGA CAGGAGAATA TCGGGTTGTT TGGCAACCGG


 


551
ACGGTTCGGT ATTTGATGCG GCGGGGCGCG GGAAAATCGG GGAAGATGTT


 


601
TATGAGCATT GCCTCGGGTG TTATCAGATG GCCCAGGTAT ATTTGGCGAA


 


651
ATACCGGGAT GTCGCGAATG ACGAGCAGAA GGTTTGGGAC TTCCGCGAAG


 


701
AGAGCAACCG GATTGCATCG GACTCGCGCG ATTATGTGTT TTATCAGAAT


 


751
ATGCGGGAAT TGATGCCCCG GGGGatgaaG gcgaacagtc ttgtggtcgg


 


801
ctatgatgcg gacggtCtgc CgcaAAAagt ctattggagt gtcgacaatg


 


851
gaaaaaaacc ccaaagtgtc gaatattatt tgaaaaacgg aaatcttttt


 


901
attgcccaat cttcgacggt aaccttgaaa acggatggcg taacggcgga


 


951
tatgcaaacc tatcatgcgc aacaaacgtt gtatttggat ggg...






This corresponds to the amino acid sequence <SEQ ID 2924; ORF 957.ng>:









g957.pep (partial)










1
MFKKFKPVLL SFFALVFAFW LGTGIAYEIN PRWFLSDTAT EVPENPNAFV



 


51
AKLARLFRNA DRAVVIVKES MRTEESLAGA VDDGPLQSEK DYLALAIRLS


 


101
RLKEKAKWFH VTEQEHGEEV WLDYYIGEGG LVAVSLSQRS PEAFVNAEYL


 


151
YRNDRPFSVN VYGGTAHGEN YETTGEYRVV WQPDGSVFDA AGRGKIGEDV


 


201
YEHCLGCYQM AQVYLAKYRD VANDEQKVWD FREESNRIAS DSRDYVFYQN


 


251
MRELMPRGMK ANSLVVGYDA DGLPQKVYWS VDNGKKPQSV EYYLKNGNLF


 


301
IAQSSTVTLK TDGVTADMQT YHAQQTLYLD G...






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2925>:










m957.seq




1
ATGTTTAAAA AATTCAAACC GGTACTGTTG TCATTTTTTG CACTTGTATT


 


51
TGCCTTTTGG CTGGGAACGG GTATTGCCTA TGAGATTAAT CCGCGTTGGT


 


101
TTTTGAGCGA TACGGCAACT GAAGTACCTA AAAATCCGAA TGCTTTTGTG


 


151
GCGAAACTTG CCCGCCTGTT CCGAAATGCC GACAGGGCGG TTGTCATCGT


 


201
GAAGGAATCG ATAAGGACGG AGGAAAATCT TGCCGGAACT GTGGATGACG


 


251
GTCCGTTGCA GTCGGAGAAG GATTATCTCG CGCTCGCTAT CCGGCTCAGT


 


301
CGTTTGAAAG AAAAGGCGAA ATGGTTTCAC GTAACGGAGC AGGAACATGG


 


351
GAAAGAGGTT TGGCTGGATT ACCATATCGG CGAGGGCGGT TTGGTTGCGG


 


401
TTTCGCTTTC GCAACGCTCG CCGGAAGCAT TTGTTAATGC CGAATATCTG


 


451
TATCGGAACG ATCGTCCGTT TTCTGTAAAT GTGTACGGCG GAACGGTTCA


 


501
CGGGGAAAAT TATGAAACGA CAGGAGAATA TCGGGTTGTT TGGCAACCAG


 


551
ACGGTTCGGT ATTTGATGCG GCGGGGCGCG GGAAAATCGG GGAAGATGTT


 


601
TATGAGCATT GCCTCGGGTG TTATCAGATG GCCCAGGTAT ATTTGGCGAA


 


651
ATACCGGGAT GTCGCGAATG ACGAGCAGAA GGTTTGGGAC TTCCGCAAAG


 


701
AGAGCAACCG AATTGCGTCG GACTCGCGCA ATTCTGTGTT TTATCAGAAT


 


751
ATGCGGGAAT TGATGCCCCG AGGGATGAAG GCGAACAGTC TTGTGGTCGG


 


801
CTATGATGCG GACGGTCTGC CGCAAAAAGT CTATTGGAGT TTCGACAATG


 


851
GAAAAAAACG CCAGAGTTTC GAATATTATT TGAAAAACGG AAATCTTTTT


 


901
ATTGCACAAT CTTCGACGGT AGCATTGAAA GCGGATGGCG TAACGGCGGA


 


951
TATGCAGACC TATCATGCGC AACAGACGTG GTATTTGGAT GGCGGGCGGA


 


1001
TTGTCCGCGA AGAGAAACAG GGAGACAGAC TGCCTGATTT TCCTTTGAAC


 


1051
TTGGAAAATT TGGAAAAAGA GGTGCGCCGT TATGCAGAGG CTGCGGCGAG


 


1101
ACGTTCGGGC GGCAGGCGCG ACCTTTCTCA CTGA






This corresponds to the amino acid sequence <SEQ ID 2926; ORF 957>:










m957.pep




1
MFKKFKPVLL SFFALVFAFW LGTGIAYEIN PRWFLSDTAT EVPKNPNAFV


 


51
AKLARLFRNA DRAVVIVKES IRTEENLAGT VDDGPLQSEK DYLALAIRLS


 


101
RLKEKAKWFH VTEQEHGKEV WLDYHIGEGG LVAVSLSQRS PEAFVNAEYL


 


151
YRNDRPFSVN VYGGTVHGEN YETTGEYRVV WQPDGSVFDA AGRGKIGEDV


 


201
YEHCLGCYQM AQVYLAKYRD VANDEQKVWD FRKESNRIAS DSRNSVFYQN


 


251
MRELMPRGMK ANSLVVGYDA DGLPQKVYWS FDNGKKRQSF EYYLKNGNLF


 


301
IAQSSTVALK ADGVTADMQT YHAQQTWYLD GGRIVREEKQ GDRLPDFPLN


 


351
LENLEKEVRR YAEAAARRSG GRRDLSH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 957 shows 95.2% identity over a 331 aa overlap with a predicted ORF (ORF 957) from N. gonorrhoeae 

g957/m957 95.2% identity in 331 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2927>:










a957.seq




1
ATGTTTAAAA AATTCAAACC GGTACTGTTG TCATTTTTTG CACTTGTATT


 


51
TGCCTTTTGG CTGGGAACGG GTATTGCCTA TGAGATTAAT CCGCGTTGGT


 


101
TTTTGAGCGA TACGGCAACT GAAAATCCGA ATGCTTTTGT GGCGAAACTT


 


151
GCCCGCCTGT TCCGAAATGC CGACAGGGCG GTTGTCATCG TGAAGGAATC


 


201
GATGAGGACG GAGGAAAGTC TTGCCGGAGC TGTGGATGAC GGTCCGTTGC


 


251
AGTCGGAGAA GGATTATCTT GCACTCGCTG TCCGGCTCAG TCGTTTGAAA


 


301
GAAAAGGCGA AATGGTTTCA CGTAACGGAG CAGGAACATG GGGAAGAGGT


 


351
TTGGCTGGAT TACTATATCG GCGAGGGCGG TTTGGTTGCG GTTTCGCTTT


 


401
CGCAACGCTC GCCGGAAGCG TTTGTTAATG CCGAATATCT GTATCGGAAC


 


451
GATCGTCCGT TTTCTGTAAA TGTGTACGGC GGAACGGTTC ACGGGGAAAA


 


501
TTATGAAACG ACAGGAGAAT ATCGGGTTGT TTGGCAACCG GACGGTTCGG


 


551
TATTTGATGC GTCGGGGCGC GGGAAAATCG GGGAAGATGT TTATGAGCAT


 


601
TGCCTCGGGT GTTATCAGAT GGCCCAGGTA TATTTGGCGA AATATCGGGA


 


651
TGTCGCGAAT GATGAGCAGA AGGTTTGGGA CTTCCGCGAA GAGAGTAACC


 


701
GGATTGCGTC GGACTCGCGC GATTCTGTGT TTTATCAGAA TATGCGGGAA


 


751
TTGATGCCCC GAGGGATGAA GGCAAACAGT CTTGTGGTCG GCTATGATGC


 


801
GGACGGTCTG CCGCAGAAAG TCTATTGGAG TTTCGACAAT GGGAAAAAAC


 


851
GCCAGAGTTT CGAATATTAT TTGAAAAACG GAAATCTTTT TATTGCACAA


 


901
TCTTCGACGG TAGCATTGAA AGCGGATGGC GTAACGGCGG ATATGCAGAC


 


951
CTATCATGCG CAACAGACGT GGTATTTAGA TGGCGGGCGG ATTGTCCGCG


 


1001
AAGAGAAACA GGGGGACAGA CTGCCTGATT TTCCTTTGAA CTTGGAAGAT


 


1051
TTGGAAAAAG AGGTGAGCCG TTATGCAGAG GCTGCGGCGA GACGTTCGGG


 


1101
CGGCAGGCGC GACCTTTCTC ACTGA






This corresponds to the amino acid sequence <SEQ ID 2928; ORF 957.a>:










a957.pep




1
MFKKFKPVLL SFFALVFAFW LGTGIAYEIN PRWFLSDTAT ENPNAFVAKL


 


51
ARLFRNADRA VVIVKESMRT EESLAGAVDD GPLQSEKDYL ALAVRLSRLK


 


101
EKAKWFHVTE QEHGEEVWLD YYIGEGGLVA VSLSQRSPEA FVNAEYLYRN


 


151
DRPFSVNVYG GTVHGENYET TGEYRVVWQP DGSVFDASGR GKIGEDVYEH


 


201
CLGCYQMAQV YLAKYRDVAN DEQKVWDFRE ESNRIASDSR DSVFYQNMRE


 


251
LMPRGMKANS LVVGYDADGL PQKVYWSFDN GKKRQSFEYY LKNGNLFIAQ


 


301
SSTVALKADG VTADMQTYHA QQTWYLDGGR IVREEKQGDR LPDFPLNLED


 


351
LEKEVSRYAE AAARRSGGRR DLSH*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 957 shows 96.3% identity over a 377 aa overlap with a predicted ORF (ORF 957) from N. meningitidis 

a957/m957 96.3% identity in 377 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2929>:










g958.seq




1
TTGGCTCGTT TATTTTCACT CAAACCACTG GTGCTGGCAT TGGGCTTCTG


 


51
TTTCGGCACG CATTGCGCCG CCGATACCGT TGCGGCGGAA GAGGCGGACG


 


101
GGCGTGTCGC AGAAGGCGGT GCGCAGGGCG CGTCCGAATC CGCACAAGCT


 


151
TCCGATTTGA CCCTCGGTTC GACCTGCCTG TTTTGCAGTA ACGAAAGCGG


 


201
CAGCCCCGAG AGAACCGAAG CCGCCGTCCA AGGCAGCGGC GAAGCATCCG


 


251
TCCCCGAAGA CTATACGCGC ATTGTTGCCG ACAGGATGGA AGGACAGTCG


 


301
AAGGTTAAGG TGCGCGCGGA AGGAAGCGTT ATCATCGAAC GGGACGGCGC


 


351
AGTCCTCAAT ACCGATTGGG CGGATTACGA CCAGTCGGGC GACACCGTTA


 


401
CCGTAGGCGA CCGGTTCGCC CTCCAACAGG ACGGTACGCT GATTCGGGGC


 


451
GAAACCCTGA CCTACAATCT CGATCAGCAG ACCGGCGAAG CGCACAACGT


 


501
CCGTATGGAA ACCGAACAAG GCGGACGGCG GCTGCAAAGC GTCAGCCGCA


 


551
CCGCCGAAAT GTTGGGCGAA GGGCGTTACA AACTGACGGA AACCCAATTC


 


601
AACACCTGTT CCGCCGGAGA TGCCGGCTGG TATGTCAAGG CCGCCTCTGT


 


651
CGAAGCCGAT CGGGGAAAAG GCATAGGCGT TGCCAAACAC GCCGCCTTCG


 


701
TGTTCGGCGG CGTTCCCCTT TTCTATACGC CTTGGGCGGA CTTCCCGCTT


 


751
GACGGCAACC GCAAAAGCGG ACTGCTCGTC CCGTCCGTAT CTGCCGGTTC


 


801
GGACGGCGTT TCCCTTTCCG TCCCCTATTA TTTCAACCTT GCCCCCAACT


 


851
TCGATGCCAC TTTCGCCCCC GGCATTATCG GCGAACGCGG CGCGACGTTT


 


901
GACGGACAAA TCCGTTACCT GCGTCCCGAT TACAGCGGAC AGACCGACCT


 


951
GACCTGGTTG CCGCACGATA AGAAAAGCGG CAGGAACAAC CGCTATCAGG


 


1001
CAAAATGGCA GCACCGGCAC GACATTTCCG ACACGCTTCA GGCGGGTGTC


 


1051
GATTTCAACC AAGTCTCCGA CAGCGGCTAC TACCGCGACT TTTACGGCGG


 


1101
CGAAGAAATC GCCGGCAACG TCAACCTCAA CCGCCGCGTA TGGCTGGATT


 


1151
ATGGCGGCAG GGCGGCGGGA GGCAGCCTGA ATGCCGGCCT TTCGGTTCAG


 


1201
AAATACCAGA CGCTGGCAAA CCAAAGCGGC TACAAAGACG AACCTTACGC


 


1251
CATCATGCCC CGCCTTTCTG CCGATTGGCA TAAAAACGCA GGCAGGGCGC


 


1301
AAATCGGCGT GTCCGCACAA TTTACCCGCT TCAGCCACGA CGGCCGCCAA


 


1351
GACGGCAGCC GACTGGTCGT GTATCCCGGT ATCAAATGGG ATTTCAGCAA


 


1401
CAGCTGGGGC TACGTCCGCC CCAAACTCGG GCTGCACGCC ACTTATTACA


 


1451
GCCTCGACAG TTTCGGCGGC AAAGCATCCC GCAGCGTCGG GCGCGTTTTG


 


1501
CCCGTTGTCA ATATCGACGG CGGCACAACC TTCGAACGCA ATACGCGCCT


 


1551
GTTCGGCGGC GGAGTCGTGC AAACCATCGA GCCGCGCCTG TTCTACAACT


 


1601
ATATTCCTGC CAAATCTCAA AACGACCTGC CCAATTTCGA TTCGTCGGAA


 


1651
AGCAGCTTCG GCTACGGGCA GCTTTTCCGC GAAAACCTCT ATTACGGCAA


 


1701
CGACCGCATC AACGCCGCCA ACAGCCTTTC CACCGCCGTG CAGAGCCGTA


 


1751
TTTTGGACGG CGCGACGGGG GAGGAGCGTT TCCGCGCCGG TATCGGTCAG


 


1801
AAATTCTATT TCAAGGATGA TGCGGTGATG CTTGACGGCA GCGTCGGCAA


 


1851
AAATCCGCGC AGCCGTTCCG ACTGGGTGGC ATTCGCCTCC GGCGGCATAG


 


1901
GCGGGCGTTT CACCCTCGAC AGCAGCATCC ACTACAACCA AAACGACAAA


 


1951
CGCGCCGAAC ATTACGCCGT CGGCGCAGGC TACCGCCCCG CCCCCGGAAA


 


2001
AGTGTTGAAC GCCCGCTACA AATACGGGCG CAACGAAAAA ATCTACCTGC


 


2051
AGGCGGACGG TTCCTATTTT TACGACAAAC TCAGCCAGCT CGACCTGTCC


 


2101
GCACAATGGC CGCTGACGCG CAACCTGTCT GCCGTCGTCC GCTACAACTA


 


2151
CGGTTTTGAA GCCAAAAAAC CGATAGAAAT GCTTGCCGGT GCAGAATACA


 


2201
AAAGCAGTTG CGGCTGCTGG GGCGCGGGCG TGTACGCCCA ACGCTACGTT


 


2251
ACCGGCGAAA ACACCTACAA AAACGCCGTC TTTTTTTCAC TTCAGTTGAA


 


2301
AGACCTCAGC AGCGTCGGCA GAAACCCCGC AGGCAGGATG GATGTCGCCG


 


2351
TTCCCGGCTA CATCCCCGCC CACTCTCTTT CCGCCGGACG CAACAAACGG


 


2401
CCCTGA






This corresponds to the amino acid sequence <SEQ ID 2930; ORF 958.ng>:










g958.pep




1
LARLFSLKPL VLALGFCFGT HCAADTVAAE EADGRVAEGG AQGASESAQA


 


51
SDLTLGSTCL FCSNESGSPE RTEAAVQGSG EASVPEDYTR IVADRMEGQS


 


101
KVKVRAEGSV IIERDGAVLN TDWADYDQSG DTVTVGDRFA LQQDGTLIRG


 


151
ETLTYNLDQQ TGEAHNVRME TEQGGRRLQS VSRTAEMLGE GRYKLTETQF


 


201
NTCSAGDAGW YVKAASVEAD RGKGIGVAKH AAFVFGGVPL FYTPWADFPL


 


251
DGNRKSGLLV PSVSAGSDGV SLSVPYYFNL APNFDATFAP GIIGERGATF


 


301
DGQIRYLRPD YSGQTDLTWL PHDKKSGRNN RYQAKWQHRH DISDTLQAGV


 


351
DFNQVSDSGY YRDFYGGEEI AGNVNLNRRV WLDYGGRAAG GSLNAGLSVQ


 


401
KYQTLANQSG YKDEPYAIMP RLSADWHKNA GRAQIGVSAQ FTRFSHDGRQ


 


451
DGSRLVVYPG IKWDFSNSWG YVRPKLGLHA TYYSLDSFGG KASRSVGRVL


 


501
PVVNIDGGTT FERNTRLFGG GVVQTIEPRL FYNYIPAKSQ NDLPNFDSSE


 


551
SSFGYGQLFR ENLYYGNDRI NAANSLSTAV QSRILDGATG EERFRAGIGQ


 


601
KFYFKDDAVM LDGSVGKNPR SRSDWVAFAS GGIGGRFTLD SSIHYNQNDK


 


651
RAEHYAVGAG YRPAPGKVLN ARYKYGRNEK IYLQADGSYF YDKLSQLDLS


 


701
AQWPLTRNLS AVVRYNYGFE AKKPIEMLAG AEYKSSCGCW GAGVYAQRYV


 


751
TGENTYKNAV FFSLQLKDLS SVGRNPAGRM DVAVPGYIPA HSLSAGRNKR


 


801
P*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2931>:










m958.seq




1
TTGGCTCGTT TATTTTCACT CAAACCACTG GTGCTGGCAT TGGGCCTCTG


 


51
CTTCGGCACG CATTGCGCCG CCGCCGATGC CGTTGCGGCG GAGGAAACGG


 


101
ACAATCCGAC CGCCGGAGAA AGCGTTCGGA GCGTGTCCGA ACCCATACAG


 


151
CCTACCAGCC TGAGCCTCGG TTCGACCTGC CTGTTTTGCA GTAACGAAAG


 


201
CGGCAGCCCC GAGAGAACCG AAGCCGCCGT CCAAGGCAGC GGCGAAGCAT


 


251
CCATCCCCGA AGACTATACG CGCATTGTTG CCGACAGGAT GGAAGGACAG


 


301
TCGCAGGTGC AGGTGCGTGC CGAAGGCAAC GTCGTCGTCG AACGCAACCG


 


351
GACGACCCTC AATACCGATT GGGCGGATTA CGACCAGTCG GGCGACACCG


 


401
TTACCGCAGG CGACCGGTTC GCCCTCCAAC AGGACGGTAC GCTGATTCGG


 


451
GGCGAAACCC TGACCTACAA TCTCGAGCAG CAGACCGGGG AAGCGCACAA


 


501
CGTCCGCATG GAAATCGAAC AAGGCGGACG GCGGCTGCAA AGCGTCAGCC


 


551
GCACCGCCGA AATGTTGGGC GAAGGGCATT ACAAACTGAC GGAAACCCAA


 


601
TTCAACACCT GTTCCGCCGG CGATGCCGGC TGGTATGTCA AGGCAGCCTC


 


651
TGTCGAAGCC GATCGGGAAA AAGGCATAGG CGTTGCCAAA CACGCCGCCT


 


701
TCGTGTTCGG CGGCGTTCCC ATTTTCTACA CCCCTTGGGC GGACTTCCCG


 


751
CTTGACGGCA ACCGCAAAAG CGGCCTGCTT GTTCCCTCAC TGTCCGCCGG


 


801
TTCGGACGGC GTTTCCCTTT CCGTTCCCTA TTATTTCAAC CTTGCCCCCA


 


851
ATCTCGATGC CACGTTCGCG CCCAGCGTGA TCGGCGAACG CGGCGCGGTC


 


901
TTTGACGGGC AGGTACGCTA CCTGCGGCCG GATTATGCCG GCCAGTCCGA


 


951
CCTGACCTGG CTGCCGCACG ACAAGAAAAG CGGCAGGAAT AACCGCTATC


 


1001
AGGCGAAATG GCAGCATCGG CACGACATTT CCGACACGCT TCAGGCGGGT


 


1051
GTCGATTTCA ACCAAGTCTC CGACAGCGGC TACTACCGCG ACTTTTACGG


 


1101
CAACAAAGAA ATCGCCGGCA ACGTCAACCT CAACCGCCGT GTATGGCTGG


 


1151
ATTATGGCGG CAGGGCGGCG GGCGGCAGCC TGAATGCCGG CCTTTCGGTT


 


1201
CTGAAATACC AGACGCTGGC AAACCAAAGC GGCTACAAAG ACAAACCGTA


 


1251
TGCCCTCATG CCGCGCCTTT CGGTCGAGTG GCGTAAAAAC ACCGGCAGGG


 


1301
CGCAAATCGG CGTGTCCGCA CAATTTACCC GATTCAGCCA CGACAGCCGC


 


1351
CAAGACGGCA GCCGCCTGGT CGTCTATCCC GACATCAAAT GGGATTTCAG


 


1401
CAACAGCTGG GGCTATGTCC GTCCCAAACT CGGACTGCAC GCCACCTATT


 


1451
ACAGCCTCAA CCGCTTCGGC AGCCAAGAAG CCCGACGCGT CAGCCGCACT


 


1501
CTGCCCATTG TCAACATCGA CAGCGGCGCA ACTTTTGAGC GGAATACGCG


 


1551
GATGTTCGGC GGAGAAGTCC TGCAAACCCT CGAGCCGCGC CTGTTCTACA


 


1601
ACTATATTCC TGCCAAATCC CAAAACGACC TGCCCAATTT CGATTCGTCG


 


1651
GAAAGCAGCT TCGGCTACGG GCAGCTCTTT CGCGAAAACC TCTATTACGG


 


1701
CAACGACAGG ATTAACACCG CAAACAGCCT TTCCGCCGCC GTGCAAAGCC


 


1751
GTATTTTGGA CGGCGCGACG GGGGAAGAGC GTTTCCGCGC CGGCATCGGT


 


1801
CAGAAATTCT ATTTCAAGGA TGATGCGGTG ATGCTTGACG GCAGCGTCGG


 


1851
CAAAAAACCG CGCAACCGTT CCGACTGGGT GGCATTTGCC TCCGGCAGCA


 


1901
TCGGCAGCCG CTTCATCCTC GACAGCAGCA TCCACTACAA CCAAAACGAC


 


1951
AAACGCGCCG AGAACTACGC CGTCGGTGCA AGCTACCGTC CCGCACAGGG


 


2001
CAAAGTGCTG AACGCCCGCT ACAAATACGG GCGCAACGAA AAAATCTACC


 


2051
TGAAGTCCGA CGGTTCCTAT TTTTACGACA AACTCAGCCA GCTCGACCTG


 


2101
TCCGCACAAT GGCCGCTGAC GCGCAACCTG TCGGCCGTCG TCCGTTACAA


 


2151
CTACGGTTTT GAAGCCAAAA AACCGATAGA GGTGCTGGCG GGTGCGGAAT


 


2201
ACAAAAGCAG TTGCGGCTGC TGGGGCGCGG GCGTGTACGC CCAACGCTAC


 


2251
GTTACCGGCG AAAACACCTA CAAAAACGCT GTCTTTTTCT CACTTCAGTT


 


2301
GAAAGACCTC AGCAGTGTCG GCAGAAACCC CGCAGACAGG ATGGATGTCG


 


2351
CCGTTCCCGG CTATATCACC GCCCACTCTC TTTCCGCCGG ACGCAACAAA


 


2401
CGACCCTGA






This corresponds to the amino acid sequence <SEQ ID 2932; ORF 958>:










m958.pep




1
LARLFSLKPL VLALGLCFGT HCAAADAVAA EETDNPTAGE SVRSVSEPIQ


 


51
PTSLSLGSTC LFCSNESGSP ERTEAAVQGS GEASIPEDYT RIVADRMEGQ


 


101
SQVQVRAEGN VVVERNRTTL NTDWADYDQS GDTVTAGDRF ALQQDGTLIR


 


151
GETLTYNLEQ QTGEAHNVRM EIEQGGRRLQ SVSRTAEMLG EGHYKLTETQ


 


201
FNTCSAGDAG WYVKAASVEA DREKGIGVAK HAAFVFGGVP IFYTPWADFP


 


251
LDGNRKSGLL VPSLSAGSDG VSLSVPYYFN LAPNLDATFA PSVIGERGAV


 


301
FDGQVRYLRP DYAGQSDLTW LPHDKKSGRN NRYQAKWQHR HDISDTLQAG


 


351
VDFNQVSDSG YYRDFYGNKE IAGNVNLNRR VWLDYGGRAA GGSLNAGLSV


 


401
LKYQTLANQS GYKDKPYALM PRLSVEWRKN TGRAQIGVSA QFTRFSHDSR


 


451
QDGSRLVVYP DIKWDFSNSW GYVRPKLGLH ATYYSLNRFG SQEARRVSRT


 


501
LPIVNIDSGA TFERNTRMFG GEVLQTLEPR LFYNYIPAKS QNDLPNFDSS


 


551
ESSFGYGQLF RENLYYGNDR INTANSLSAA VQSRILDGAT GEERFRAGIG


 


601
QKFYFKDDAV MLDGSVGKKP RNRSDWVAFA SGSIGSRFIL DSSIHYNQND


 


651
KRAENYAVGA SYRPAQGKVL NARYKYGRNE KIYLKSDGSY FYDKLSQLDL


 


701
SAQWPLTRNL SAVVRYNYGF EAKKPIEVLA GAEYKSSCGC WGAGVYAQRY


 


751
VTGENTYKNA VFFSLQLKDL SSVGRNPADR MDVAVPGYIT AHSLSAGRNK


 


801
RP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 958 shows 89.3% identity over a 802 aa overlap with a predicted ORF (ORF 958) from N. gonorrhoeae 

m958/g958 89.3% identity in 802 aa overlap








The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2933>:










a958.seq




1
TTGGCTCGTT TATTTTCACT CAAACCACTG GTGCTGGCAT TGGGCTTCTG


 


51
TTTCGGCACG CATTGCGCCG CCGCCGATGC CGTTGCGGCG GAGGAAACGG


 


101
ACAATCCGAC CGCCGGAGGA AGCGTTCGGA GCGTGTCCGA ACCCATACAG


 


151
CCTACCAGCC TGAGCCTCGG TTCGACCTGC CTGTTTTGCA GTAACGAAAG


 


201
CGGCAGCCCC GAGAGAACCG AAGCCGCCGT CCAAGGCAGC GGCGAAGCAT


 


251
CCATCCCCGA AGACTATACG CGCATTGTTG CCGACAGGAT GGAAGGACAG


 


301
TCGCAGGTGC AGGTGCGTGC CGAAGGCAAC GTCGTCGTCG AACGCAATCG


 


351
GACGACCCTC AATGCCGATT GGGCGGATTA CGACCAGTCG GGCGACACCG


 


401
TTACCGCAGG CGACCGGTTC GCCCTCCAAC AGGACGGTAC GCTGATTCGG


 


451
GGCGAAACCC TGACCTACAA TCTCGAGCAG CAGACCGGGG AAGCGCACAA


 


501
CGTCCGTATG GAAACCGAAC ACGGCGGACG GCGGCTGCAA AGCGTCAGCC


 


551
GCACCGCCGA AATGTTGGGC GAAGGGCATT ACAAACTGAC GGAAACCCAA


 


601
TTCAACACCT GTTCCGCCGG CGATGCCGGC TGGTATGTCA AGGCCGCTTC


 


651
CGTCGAAGCC GATCGGGAAA AAGGCATAGG CGTTGCCAAA CACGCCGCCT


 


701
TCGTGTTCGG CGGCGTTCCC ATTTTCTACA CCCCTTGGGC GGACTTCCCG


 


751
CTTGACGGCA ACCGCAAAAG CGGCCTGCTC GTTCCCTCAC TGTCCGCCGG


 


801
TTCGGACGGC GTTTCCCTTT CCGTTCCCTA TTATTTCAAC CTTGCCCCCA


 


851
ATCTCGATGC CACGTTCGCG CCCGGCGTGA TCGGCGAACG CGGCGCGGTC


 


901
TTTGACGGGC AGGTACGCTA CCTGCGGCCG GATTATGCCG GCCAGTCCGA


 


951
CCTGACCTGG CTGCCGCACG ACAAGAAAAG CGGCAGGAAT AACCGCTATC


 


1001
AGGCGAAATG GCAGCACCGG CACGACATTT CCGACACGCT TCAGGCGGGT


 


1051
GTCGATTTCA ACCAAGTCTC CGACAGCGGC TACTACCGCG ACTTTTACGG


 


1101
CAACAAAGAA ATCGCCGGCA ACGTCAACCT CAACCGCCGT GTATGGCTGG


 


1151
ATTATGGCGG CAGGGCGGCG GGCGGCAGCC TGAATGCCGG CCTTTCGGTT


 


1201
CTGAAATACC AGACGCTGGC AAACCAAAGC GGCTACAAAG ACAAACCGTA


 


1251
TGCCCTGATG CCGCGCCTTT CCGCCGATTG GCGCAAAAAC ACCGGCAGGG


 


1301
CGCAAATCGG CGTGTCCGCC CAATTTACCC GCTTCAGCCA CGACAGCCGC


 


1351
CAAGACGGCA GCCGCCTCGT CGTCTATCCC GACATCAAAT GGGATTTCAG


 


1401
CAACAGCTGG GGTTACGTCC GTCCCAAACT CGGACTGCAC GCCACCTATT


 


1451
ACAGCCTCAA CCGCTTCGGC AGCCAAGAAG CCCGACGCGT CAGCCGCACT


 


1501
CTGCCCATCG TCAACATCGA CAGCGGCATG ACCTTCGAAC GCAATACGCG


 


1551
GATGTTCGGC GGCGGAGTCC TGCAAACCCT CGAGCCGCGC CTGTTCTACA


 


1601
ACTATATTCC TGCCAAATCC CAAAACGACC TGCCCAATTT CGATTCGTCG


 


1651
GAAAGCAGCT TCGGCTACGG GCAGCTTTTT CGTGAAAACC TCTATTACGG


 


1701
CAACGACAGG ATTAACACCG CAAACAGCCT TTCCGCCGCC GTGCAAAGCC


 


1751
GTATTTTGGA CGGCGCGACG GGGGAAGAGC GTTTCCGCGC CGGCATCGGG


 


1801
CAGAAATTCT ACTTCAAAAA CGACGCAGTC ATGCTTGACG GCAGTGTCGG


 


1851
CAAAAAACCG CGCAGCCGTT CCGACTGGGT GGCATTCGCC TCCAGCGGCA


 


1901
TCGGCAGCCG CTTCATCCTC GACAGCAGCA TCCACTACAA CCAAAACGAC


 


1951
AAACGCGCCG AGAACTACGC CGTCGGTGCA AGCTACCGTC CCGCACAGGG


 


2001
CAAAGTGCTG AACGCCCGCT ACAAATACGG GCGCAACGAA AAAATCTACC


 


2051
TGAAGTCCGA CGGTTCCTAT TTTTACGACA AACTCAGCCA GCTCGACCTG


 


2101
TCCGCACAAT GGCCGCTGAC GCGCAACCTG TCGGCCGTCG TCCGTTACAA


 


2151
CTACGGTTTT GAAGCCAAAA AACCGATAGA GGTGCTGGCG GGTGCGGAAT


 


2201
ACAAAAGCAG TTGCGGCTGC TGGGGCGCGG GCGTGTACGC CCAACGCTAC


 


2251
GTTACCGGCG AAAACACCTA CAAAAACGCT GTCTTTTTCT CACTTCAGTT


 


2301
GAAAGACCTC AGCAGTGTCG GCAGAAACCC CGCAGACAGG ATGGATGTCG


 


2351
CCGTTCCCGG CTATATCCCC GCCCACTCTC TTTCCGCCGG ACGCAACAAA


 


2401
CGGCCCTGA






This corresponds to the amino acid sequence <SEQ ID 2934; ORF 958.a>:










a958.pep




1
LARLFSLKPL VLALGFCFGT HCAAADAVAA EETDNPTAGG SVRSVSEPIQ


 


51
PTSLSLGSTC LFCSNESGSP ERTEAAVQGS GEASIPEDYT RIVADRMEGQ


 


101
SQVQVRAEGN VVVERNRTTL NADWADYDQS GDTVTAGDRF ALQQDGTLIR


 


151
GETLTYNLEQ QTGEAHNVRM ETEHGGRRLQ SVSRTAEMLG EGHYKLTETQ


 


201
FNTCSAGDAG WYVKAASVEA DREKGIGVAK HAAFVFGGVP IFYTPWADFP


 


251
LDGNRKSGLL VPSLSAGSDG VSLSVPYYFN LAPNLDATFA PGVIGERGAV


 


301
FDGQVRYLRP DYAGQSDLTW LPHDKKSGRN NRYQAKWQHR HDISDTLQAG


 


351
VDFNQVSDSG YYRDFYGNKE IAGNVNLNRR VWLDYGGRAA GGSLNAGLSV


 


401
LKYQTLANQS GYKDKPYALM PRLSADWRKN TGRAQIGVSA QFTRFSHDSR


 


451
QDGSRLVVYP DIKWDFSNSW GYVRPKLGLH ATYYSLNRFG SQEARRVSRT


 


501
LPIVNIDSGM TFERNTRMFG GGVLQTLEPR LFYNYIPAKS QNDLPNFDSS


 


551
ESSFGYGQLF RENLYYGNDR INTANSLSAA VQSRILDGAT GEERFRAGIG


 


601
QKFYFKNDAV MLDGSVGKKP RSRSDWVAFA SSGIGSRFIL DSSIHYNQND


 


651
KRAENYAVGA SYRPAQGKVL NARYKYGRNE KIYLKSDGSY FYDKLSQLDL


 


701
SAQWPLTRNL SAVVRYNYGF EAKKPIEVLA GAEYKSSCGC WGAGVYAQRY


 


751
VTGENTYKNA VFFSLQLKDL SSVGRNPADR MDVAVPGYIP AHSLSAGRNK


 


801
RP*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 957 shows 96.3% identity over a 377 aa overlap with a predicted ORF (ORF 957) from N. meningitidis 

a958/m958 98.1% identity in 802 aa overlap








The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2935>:










g959.seq




1
ATGAACATCA AACACCTTCT CTTGACCGCC GCCGCAACCG CACTGTTGGG


 


51
CATTTCCGCC CCCGCACTCG CCCACCACGA CGGACACGGC GATGACGACC


 


101
ACGGACACGC CGCACACCAA CACGGCAAAC AAGACAAAAT CATCAGCCGC


 


151
GCCCAAGCCG AAAAAGCGGC TTGGGCGCGT GTCGGCGGCA AAATCACCGA


 


201
CATCGATCTC GAACACGACG ACGGCCGTCC GCACTATGAT GTCGAAATCG


 


251
TCAAAAACGG ACAGGAATAC AAAGTCGTTG TCGATGCCCG TACCGGCCGC


 


301
GTGATTTCCT CCCGCCGCGA CGACTGA






This corresponds to the amino acid sequence <SEQ ID 2936; ORF 959.ng>:










g959.pep




1
MNIKHLLLTA AATALLGISA PALAHHDGHG DDDHGHAAHQ HGKQDKIISR


 


51
AQAEKAAWAR VGGKITDIDL EHDDGRPHYD VEIVKNGQEY KVVVDARTGR


 


101
VISSRRDD*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2937>:










m959.seq




1
ATGAACATCA AACACCTTCT CTTGACCTCC GCCGCAACCG CACTGCTGAG


 


51
CATTTCCGCC CCCGCGCTCG CCCACCACGA CGGACACGGC GATGACGACC


 


101
ACGGACACGC CGCACACCAA CACAACAAAC AAGACAAAAT CATCAGCCGC


 


151
GCCCAAGCCG AAAAAGCAGC GTTGGCGCGT GTCGGCGGCA AAATCACCGA


 


201
CATCGATCTC GAACACGACA ACGGCCGTCC GCACTATGAT GTCGAAATCG


 


251
TCAAAAACGG ACAGGAATAC AAAGTCGTTG TCGATGCCCG TACCGGCCGC


 


301
GTGATTTCCT CCCGCCGCGA CGACTGA






This corresponds to the amino acid sequence <SEQ ID 2938; ORF 959>:










m959.pep




1
MNIKHLLLTS AATALLSISA PALAHHDGHG DDDHGHAAHQ HNKQDKIISR


 


51
AQAEKAALAR VGGKITDIDL EHDNGRPHYD VEIVKNGQEY KVVVDARTGR


 


101
VISSRRDD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 959 shows 95.4% identity over a 108 aa overlap with a predicted ORF (ORF 959) from N. gonorrhoeae 

m959/g959 95.4% identity in 108 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2939>:










a959.seq




1
ATGAACTTCA AACGCCTTCT CTTGACCGCC GCCGCAACCG CACTGATGGG


 


51
CATTTCCGCC CCCGCACTCG CCCACCACGA CGGACACGGC GATGACGACC


 


101
ACGGACACGC CGCACACCAA CACAGCAAAC AAGACAAAAT CATCAGCCGC


 


151
GCCCAAGCCG AAAAAGCAGC GTTGGCGCGT GTCGGCGGCA AAATCACCGA


 


201
CATCGATCTC GAACACGACA ACGGCCGTCC GCACTATGAT GTCGAAATCG


 


251
TCAAAAACGG ACAGGAATAC AAAGTCGTTG TCGATGCCCG TACCGGCCGC


 


301
GTGATTTCCT CCCGCCGCGA CGACTGA






This corresponds to the amino acid sequence <SEQ ID 2940; ORF 959.a>:










a959.pep




1
MNFKRLLLTA AATALMGISA PALAHHDGHG DDDHGHAAHQ HSKQDKIISR


 


51
AQAEKAALAR VGGKITDIDL EHDNGRPHYD VEIVKNGQEY KVVVDARTGR


 


101
VISSRRDD*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 959 shows 94.4% identity over a 108 aa overlap with a predicted ORF (ORF 959) from N. meningitidis 

a959/m959 94.4% identity in 108 aa overlap





g960.seq not found yet

g960.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2941>:










m960.seq




1
ATGCAAGTAA ATATTCAGAT TCCCTGTATG CTGTACAGAC GCGGGAGTGT


 


51
TAAGCCCCCC TTGTTTGAAG CTCCGCGGCT CCTGCCGAGC TTCACCGACC


 


101
CCGTTGTGCC CAAGCTCTCT GCTCCCGGCG GCTACATTGT CGACATCCCC


 


151
AAAGGCAATC TGAAAACCGA AATCGAAAAG CTGGCCAAAC AGCCCGAGTA


 


201
TGCCTATCTG AAACAGCTCC AAGTAGCGAA AAACGTCAAC TGGAACCAGG


 


251
TGCAACTGGC TTACGATAAA TGGGACTATA AGCAGGAAGG CTTAACCAGA


 


301
GCCGGTGCAG CGATTATCGC GCTGGCTGTT ACCGTGGTTA CTGCGGGCGC


 


351
GGGAGTCGGA GCCGCACTAG GCTTAAACGG CGCAGCCGCA GCAGCGGCCG


 


401
ATGCCGCCTT TGCCTCACTC GCTTCTCAGG CTTCCGTATC GCTCATCAAC


 


451
AATAAAGGCG ATGTCGGCAA AACCCTGAAG GAACTGGGCA GAAGCCGCAC


 


501
GGTAAAAAAT CTGGTTGTAG CGGCGGCAAC GGCAGGCGTA TCCAACAAAC


 


551
TCGGTGCCTC TTCCCTTGCC ACTTGGAGCG AAACCCCTTG GGTAAACAAC


 


601
CTCAACGTTA ACCTGGCCAA TGCGGGCAGT GCCGCGCTGA TCAACACCGC


 


651
TGTTAACGGC GGCAGCCTGA AAGACAATCT GGAGGCAAAT ATCCTGGCGG


 


701
CATTGGTGAA TACCGCGCAT GGGGAGGCGG CGAGTAAGAT CAAAGGACTG


 


751
GATCAGCACT ATGTCGCCCA CAAAATCGCT CATGCCGTAG CGGGCTGTGC


 


801
GGCTGCAGCG GCGAATAAGG GCAAATGTCA GGACGGCGCG ATCGGTGCGG


 


851
CTGTGGGTGA GATTGTCGGG GAGGCTTTGG TTAAAAATAC CGATTTTAGC


 


901
GATATGACCC CGGAACAATT AGATCTGGAA GTTAAGAAAA TTACCGCCTA


 


951
TGCCAAACTT GCGGCAGGTA CAGTTGCAGG CGTAACGGGA GGAGATGTCA


 


1001
ATACTGCTGC ACAAACCGCA CAAAACGCGG TAGAAAATAA TGCGGTTAAA


 


1051
GCTGTTGTAA CTGCTGCAAA AGTGGTTTAT AAGGTAGCCA GAAAAGGATT


 


1101
AAAAAACGGG AAAATCAACG TTAGAGATTT AAAACAGACG TTGAAAGACG


 


1151
AAGGTTATAA TTTAGCCGAC AACCTGACCA CCTTATTCGA CGAAACATTG


 


1201
GATTGGAACG ATGCCAAAGC CGTTATTGAT ATTGTCGTCG GAACAGAGCT


 


1251
GAATCGCGCT AATAAAGGGG AAGCGGCACA AAAGGTCAAG GAAGTTTTAG


 


1301
AAAAAAATCG TCCTTATATC CCTAATAAAG GTGCTGTACC GAATATGAGT


 


1351
ACATACATGA AAAATAATCC TTTTGGAAAA CAGCTGGCTC AAATTTCAGA


 


1401
AAAGACAACG CTTCCGACGC AGCAAGGGCA GTCTGTCTTC TTGGTAAAAA


 


1451
GAAACCAAGG GTTATTAAAA ACCGGTGATA GGTTTTATTT AGATGGCCAA


 


1501
CATAAAAATC ATTTAGAGGT TTTTGATAAA AATGGGAACT TTAAGTTTGT


 


1551
TCTAAATATG GATGGTTCGC TTAACCAAAT GAAAACTGGG GCAGCAAAAG


 


1601
GTCGTAAATT AAACTTAAAA TAG






This corresponds to the amino acid sequence <SEQ ID 2942; ORF 960>:










m960.pep




1
MQVNIQIPCM LYRRGSVKPP LFEAPRLLPS FTDPVVPKLS APGGYIVDIP


 


51
KGNLKTEIEK LAKQPEYAYL KQLQVAKNVN WNQVQLAYDK WDYKQEGLTR


 


101
AGAAIIALAV TVVTAGAGVG AALGLNGAAA AAADAAFASL ASQASVSLIN


 


151
NKGDVGKTLK ELGRSRTVKN LVVAAATAGV SNKLGASSLA TWSETPWVNN


 


201
LNVNLANAGS AALINTAVNG GSLKDNLEAN ILAALVNTAH GEAASKIKGL


 


251
DQHYVAHKIA HAVAGCAAAA ANKGKCQDGA IGAAVGEIVG EALVKNTDFS


 


301
DMTPEQLDLE VKKITAYAKL AAGTVAGVTG GDVNTAAQTA QNAVENNAVK


 


351
AVVTAAKVVY KVARKGLKNG KINVRDLKQT LKDEGYNLAD NLTTLFDETL


 


401
DWNDAKAVID IVVGTELNRA NKGEAAQKVK EVLEKNRPYI PNKGAVPNMS


 


451
TYMKNNPFGK QLAQISEKTT LPTQQGQSVF LVKRNQGLLK TGDRFYLDGQ


 


501
HKNHLEVFDK NGNFKFVLNM DGSLNQMKTG AAKGRKLNLK *






a960.seq not found yet

a960.pep not found yet

g961.seq not found yet

g961.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2943>:










m961.seq




1
ATGAGCATGA AACACTTTCC AGCCAAAGTA CTGACCACAG CCATCCTTGC


 


51
CACTTTCTGT AGCGGCGCAC TGGCAGCCAC AAGCGACGAC GATGTTAAAA


 


101
AAGCTGCCAC TGTGGCCATT GTTGCTGCCT ACAACAATGG CCAAGAAATC


 


151
AACGGTTTCA AAGCTGGAGA GACCATCTAC GACATTGGTG AAGACGGCAC


 


201
AATTACCCAA AAAGACGCAA CTGCAGCCGA TGTTGAAGCC GACGACTTTA


 


251
AAGGTCTGGG TCTGAAAAAA GTCGTGACTA ACCTGACCAA AACCGTCAAT


 


301
GAAAACAAAC AAAACGTCGA TGCCAAAGTA AAAGCTGCAG AATCTGAAAT


 


351
AGAAAAGTTA ACAACCAAGT TAGCAGACAC TGATGCCGCT TTAGCAGATA


 


401
CTGATGCCGC TCTGGATGAA ACCACCAACG CCTTGAATAA ATTGGGAGAA


 


451
AATATAACGA CATTTGCTGA AGAGACTAAG ACAAATATCG TAAAAATTGA


 


501
TGAAAAATTA GAAGCCGTGG CTGATACCGT CGACAAGCAT GCCGAAGCAT


 


551
TCAACGATAT CGCCGATTCA TTGGATGAAA CCAACACTAA GGCAGACGAA


 


601
GCCGTCAAAA CCGCCAATGA AGCCAAACAG ACGGCCGAAG AAACCAAACA


 


651
AAACGTCGAT GCCAAAGTAA AAGCTGCAGA AACTGCAGCA GGCAAAGCCG


 


701
AAGCTGCCGC TGGCACAGCT AATACTGCAG CCGACAAGGC CGAAGCTGTC


 


751
GCTGCAAAAG TTACCGACAT CAAAGCTGAT ATCGCTACGA ACAAAGCTGA


 


801
TATTGCTAAA AACTCAGCAC GCATCGACAG CTTGGACAAA AACGTAGCTA


 


851
ATCTGCGCAA AGAAACCCGC CAAGGCCTTG CAGAACAAGC CGCGCTCTCC


 


901
GGCCTGTTCC AACCTTACAA CGTGGGTCGG TTCAATGTAA CGGCTGCAGT


 


951
CGGCGGCTAC AAATCCGAAT CGGCAGTCGC CATCGGTACC GGCTTCCGCT


 


1001
TTACCGAAAA CTTTGCCGCC AAAGCAGGCG TGGCAGTCGG CACTTCGTCC


 


1051
GGTTCTTCCG CAGCCTACCA TGTCGGCGTC AATTACGAGT GGTAA






This corresponds to the amino acid sequence <SEQ ID 940; ORF 2944>:










m961.pep




1
MSMKHFPAKV LTTAILATFC SGALAATSDD DVKKAATVAI VAAYNNGQEI


 


51
NGFKAGETIY DIGEDGTITQ KDATAADVEA DDFKGLGLKK VVTNLTKTVN


 


101
ENKQNVDAKV KAAESEIEKL TTKLADTDAA LADTDAALDE TTNALNKLGE


 


151
NITTFAEETK TNIVKIDEKL EAVADTVDKH AEAFNDIADS LDETNTKADE


 


201
AVKTANEAKQ TAEETKQNVD AKVKAAETAA GKAEAAAGTA NTAADKAEAV


 


251
AAKVTDIKAD IATNKADIAK NSARIDSLDK NVANLRKETR QGLAEQAALS


 


301
GLFQPYNVGR FNVTAAVGGY KSESAVAIGT GFRFTENFAA KAGVAVGTSS


 


351
GSSAAYHVGV NYEW*






a961.seq not found yet

a961.pep not found yet

g972.seq not found yet

g972.pep not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2945>:










m972.seq




1
TTGACTAACA GGGGGGGAGC GAAATTAAAA ACCArTTCCA AGAGTAGTGA


 


51
ACGAATGAGT GAAGTTGAAT ATTTCTCACA CTTTATATCG GACGGAAAAG


 


101
GGAAGCTTTT AGAAATTCCG CAGCGAAGAG GTAAGCAAGA CggGGTTTTT


 


151
GTTGATTGGA TTTCATTCAC ATTCCATGAA GATACTTTAC TGAAAGTTTC


 


201
CGGTTGCCCT TTATTTTCTG ATGCTGAATA CATGTATGTA TTAAGCAGAA


 


251
AGCTGGAAGA AATTCTAGGT TTTGGCATAA CGCGCAAATG CAAATCAAGG


 


301
GGCAACAAAT TCTATGAATC CATGTATAGG TTAGGTTCGG ATGATGTTGA


 


351
TTATGGAGAG GTGCATTTCG GArGTCAGCG CAATACTGTT TTAGTTGAGT


 


401
TGAAAGGTAC TGGTTGCAGC GTTGCAAGTC CGGGTTGGGA GTTGAGGCTA


 


451
AAGCAGTTTC TCGATGATTC GATAAGGACA AGAATAACGC GAATTGACCT


 


501
AGCACTTGAT TTTTTTGATG GAGAGTACAC GCCGGATCAG GCGTTGTTAG


 


551
ATCACGATAA TGGTTTTTTT GATAACAGCA ATCAAAGGCC GAAATCTGAA


 


601
ACGATCGGTA CGGCTTGGCG GAATGAGGAC GGGAGCGGCA AGACATTTTA


 


651
TGTAGGTCGC AAGAAAAATT CTCGTTTTGT TCGTGTTTAT GAGAAAGGCA


 


701
GGCAGCTTGG AGATAAAGAA AGCAAATGGG TAAGGTTCGA GATCCAGTTT


 


751
AATTATGGAG ATATAGAAAT ACCCTTGGAT ATTTTAATAA ATCAGGGTTC


 


801
GTATTTCTGT GGAGCTTTTC CAATTTGTAG AAAATTTAAA AATATGCCGG


 


851
TTCCCGAAAG GTTTGATCAG AGAAAGAAAA AGCTTAATTT AACTTTCGAG


 


901
CATAAATTGC ATTACGCGAA AAACGCGGTT GGAAAACTGG TCAATTTCAT


 


951
GATTGAAATG GGTTTTGATA ATAGCGAAAT TGTGGAATCT TTAAAGGCAG


 


1001
ATTCGGGATT TCCCAAAGGA TTAGAACCTG AAAAATATGC TCTGGAAATG


 


1051
TTAAGGGACG GTTTGAAACA CGGTTTTATT CATGAACAGC CGGATATTGA


 


1101
TTTGGAAATT GAACTTGATG AATTGGGGGT TATTGCTTTT AAAAATTCTG


 


1151
ACAAATTCGA TAGGGAAAAA AGGCTTTTTA GTCCTGATTA TGATGTCGAG


 


1201
AAAGAAAGGA AATATCAGGA ATATTTAAGT AAAGTTTATC ATCAAAATGT


 


1251
AGATTATGAT TATTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2946; ORF 972>:










m972.pep




1
LTNRGGAKLK TXSKSSERMS EVEYFSHFIS DGKGKLLEIP QRRGKQDGVF


 


51
VDWISFTFHE DTLLKVSGCP LFSDAEYMYV LSRKLEEILG FGITRKCKSR


 


101
GNKFYESMYR LGSDDVDYGE VHFGXQRNTV LVELKGTGCS VASPGWELRL


 


151
KQFLDDSIRT RITRIDLALD FFDGEYTPDQ ALLDHDNGFF DNSNQRPKSE


 


201
TIGTAWRNED GSGKTFYVGR KKNSRFVRVY EKGRQLGDKE SKWVRFEIQF


 


251
NYGDIEIPLD ILINQGSYFC GAFPICRKFK NMPVPERFDQ RKKKLNLTFE


 


301
HKLHYAKNAV GKLVNFMIEM GFDNSEIVES LKADSGFPKG LEPEKYALEM


 


351
LRDGLKHGFI HEQPDIDLEI ELDELGVIAF KNSDKFDREK RLFSPDYDVE


 


401
KERKYQEYLS KVYHQNVDYD YF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2947>:










a972.seq




1
TTGACTAACA GGGGGGGAGC GAAATTAAAA ACCAATTCCA AGAGTAGTGA


 


51
ACGAATGAGT GAAGTTGAAT ATTTCTCACA CTTTATATCG GACGGAAAAG


 


101
GGAAGCTTTT AGAAATTCCG CAGCGAAGAG GTAAGCAAGA CGGGGTTTTT


 


151
GTTGATTGGA TTTCATTCAC ATTCCATGAA GATACTTTAC TGAAAGTTTC


 


201
CGGTTGCCCT TTATTTTCTG ATGCTGAATA CATGTATGTA TTAAGCAGAA


 


251
AGCTGGAAGA AATTCTAGGT TTTGGCATAA CGCGCAAATG CAAATCAAGG


 


301
GGCAACAAAT TCTATGAATC CATGTATAGG TTAGGTTCGG ATGATGTTGA


 


351
TTATGGAGAG GTGCATTTCG GAGGTCAGCG CAATACTGTT TTAGTTGAGT


 


401
TGAAAGGTAC TGGTTGCAGC GTTGCAAGTC CGGGTTGGGA GTTGAGGCTA


 


451
AAGCAGTTTC TCGATGATTC GATAAGGACA AGAATAACGC GAATTGACCT


 


501
AGCACTTGAT TTTTTTGATG GAGAGTACAC GCCGGATCAG GCGTTGTTAG


 


551
ATCACGATAA TGGTTTTTTT GATAACAGCA ATCAAAGGCC GAAATCTGAA


 


601
ACGATCGGTA CGGCTTGGCG GAATGAGGAC GGGAGCGGCA AGACATTTTA


 


651
TGTAGGTCGC AAGAAAAATT CTCGTTTTGT TCGTGTTTAT GAGAAAGGCA


 


701
GGCAGCTTGG AGATAAAGAA AGCAAATGGG TAAGGTTCGA GATCCAGTTT


 


751
AATTATGGAG ATATAGAAAT ACCCTTGGAT ATTTTAATAA ATCAGGGTTC


 


801
GTATTTCTGT GGAGCTTTTC CAATTTGTAG AAAATTTAAA AATATGCCGG


 


851
TTCCCGAAAG GTTTGATCAG AGAAAGAAAA CGCTTAATTT AACTTTCGAG


 


901
CATAAATTGC ATTACGCGAA AAACGCGGTT GGAAAACTGG TCAATTTCAT


 


951
GATTGAAATG GGTTTTGATA ATAGCGAAAT TGTGGAATCT TTAAAGGCAG


 


1001
ATTCGGGATT TCCCAAAGGA TTAGAACCTG AAAAATATGC TCTGGAAATG


 


1051
TTAAGGGACG GTTTGAAACA CGGTTTTATT CATGAACAGC CGGATATTGA


 


1101
TTTGGAAATT GAACTTGATG AATTGGGGGT TATTGCTTTT AAAAATTCTG


 


1151
ACAAATTCGA TAGGGAAAAA AGGCTTTTTA GTCCTGATTA TGATGTCGAG


 


1201
AAAGAAAGGA AATATCAGGA ATATTTAAGT AAAGTTTATC ATCAAAATGT


 


1251
AGATTATGAT TATTTTTAA






This corresponds to the amino acid sequence <SEQ ID 2948; ORF 972.a>:










a972.pep




1
LTNRGGAKLK TNSKSSERMS EVEYFSHFIS DGKGKLLEIP QRRGKQDGVF


 


51
VDWISFTFHE DTLLKVSGCP LFSDAEYMYV LSRKLEEILG FGITRKCKSR


 


101
GNKFYESMYR LGSDDVDYGE VHFGGQRNTV LVELKGTGCS VASPGWELRL


 


151
KQFLDDSIRT RITRIDLALD FFDGEYTPDQ ALLDHDNGFF DNSNQRPKSE


 


201
TIGTAWRNED GSGKTFYVGR KKNSRFVRVY EKGRQLGDKE SKWVRFEIQF


 


251
NYGDIEIPLD ILINQGSYFC GAFPICRKFK NMPVPERFDQ RKKTLNLTFE


 


301
HKLHYAKNAV GKLVNFMIEM GFDNSEIVES LKADSGFPKG LEPEKYALEM


 


351
LRDGLKHGFI HEQPDIDLEI ELDELGVIAF KNSDKFDREK RLFSPDYDVE


 


401
KERKYQEYLS KVYHQNVDYD YF*






m972/a972 99.3% identity in 422 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2949>:










g973.seq




1
ATGGACGGCG CACAACCGAA AACAAATTTT TTTGAACGCC TGATTGCCCG


 


51
actCGCCCGC GAACCCGATT CCGCCGAAGA CGTATTAAAC CTGCTTCGGC


 


101
AGGCGCACGA ACAGGAAGTT TTTGATGCCG ACACACTGAC CCGGCTGGAA


 


151
AAAGTATTGG ACTTTGCCGA GCTGGAAGTG CGCGATGCGA TGATTACGCG


 


201
CAGCCGCATG AACGTATTGA AAGAAAACGA CAGCATCGAA CGCATCACCG


 


251
CCTACGTCAT CGATACCGCC CATTCGCGCT TCCCCGTCAT CGGCGAAGAC


 


301
AAAGACGAAG TTTTGGGCAT TTTGCACGCC AAAGACCTGC TCAAATATAT


 


351
GTTCAACCCC GAGCAGTTCC ACCTGAAATC CGTCTTGCGC CCTGCCGTTT


 


401
TCGTGCCCGA AGGCAAATCT TTGACCGCCC TTTTAAAAGA GTTCCGCGAA


 


451
CAGCGCAACC ATATGGCAAT CGTCATCGAC GAATACGGCG GCACGTCGGG


 


501
TTTGGTCACC TTTGAAGACA TCATCGAGCa aatcgtcggt gacaTCGAAG


 


551
ACGAGTTTGA CGAAGACGAA AGCGccgacg acatCCACTC cgTTTccgCC


 


601
GAACGCTGGC GCATCCacgc ggctaCCGAA ATCGAAGaca TCAACGCCTT


 


651
TTTCGGTACG GAatacggca gcgaagaagc cgacaccatc ggcggctTGG


 


701
TCATTCAGGA ATTGGGACAC CTGCCCGTGC GCGGCGAAAA AGTCCTTAtc


 


751
ggcgGTTTGC agttcaccgt CGCCCGCGCC GACAACCGCC GCCTGCACAC


 


801
GCTGATGGCG ACCCGCGTGA AGTAAGCAGA GCCTGCCcgc accgccgttT


 


851
CTGCacAGTT TAG






This corresponds to the amino acid sequence <SEQ ID 2950; ORF 973.ng>:










g973.pep




1
MDGAQPKTNF FERLIARLAR EPDSAEDVLN LLRQAHEQEV FDADTLTRLE


 


51
KVLDFAELEV RDAMITRSRM NVLKENDSIE RITAYVIDTA HSRFPVIGED


 


101
KDEVLGILHA KDLLKYMFNP EQFHLKSVLR PAVFVPEGKS LTALLKEFRE


 


151
QRNHMAIVID EYGGTSGLVT FEDIIEQIVG DIEDEFDEDE SADDIHSVSA


 


201
ERWRIHAATE IEDINAFFGT EYGSEEADTI GGLVIQELGH LPVRGEKVLI


 


251
GGLQFTVARA DNRRLHTLMA TRVK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2951>:










m973.seq




1
ATGGACGGCG CACAACCGAA AACGAATTTT TTTGAACGCC TGATTGCCCG


 


51
ACTCGCCCGC GAACCCGATT CCGCCGAAGA CGTATTAAAC CTGCTTCGGC


 


101
AGGCGCACGA GCAGGAAGTT TTTGATGCGG ATACGCTTTT AAGATTGGAA


 


151
AAAGTCCTCG ATTTTTCCGA TTTGGAAGTG CGCGACGCGA TGATTACGCG


 


201
CAGCCGTATG AACGTTTTAA AAGAAAACGA CAGCATCGAG CGCATCACCG


 


251
CCTACGTTAT CGATACCGCC CATTCGCGCT TCCCCGTCAT CGGCGAAGAC


 


301
AAAGACGAAG TTTTGGGCAT TTTGCACGCC AAAGACCTGC TCAAATATAT


 


351
GTTTAACCCC GAGCAGTTCC ACCTCAAATC CATTCTCCGC CCCGCCGTCT


 


401
TCGTCCCCGA AGGCAAATCG CTGACCGCCC TTTTAAAAGA GTTCCGCGAA


 


451
CAGCGCAACC ATATGGCGAT TGTCATCGAC GAATACGGCG GCACATCCGG


 


501
CTTGGTCACC TTTGAAGACA TCATCGAGCA AATCGTCGGC GAAATCGAAG


 


551
ACGAGTTTGA CGAAGACGAT AGCGCCGACA ATATCCATGC CGTTTCTTCm


 


601
GaACGcTGGC GCATCCATGC AGCTACCGAA ATCGAAGACA TCAACACCTT


 


651
CTTCGGCACG GAATACAGCA kCGAAGAAGC CGACACCATT GGCGGCCTGG


 


701
TCATTCAAGA GTTGGGACAT CTGCCCGTGC GCGGCGAAAA AGTCCTTATC


 


751
GGCGGTTTGC AGTTCACCGT CGCACGCGCC GACAACCGCC GCCTGCATAC


 


801
GCTGATGGCG ACCCGCGTGA AGTAA






This corresponds to the amino acid sequence <SEQ ID 2952; ORF 973>:










m973.pep




1
MDGAQPKTNF FERLIARLAR EPDSAEDVLN LLRQAHEQEV FDADTLLRLE


 


51
KVLDFSDLEV RDAMITRSRM NVLKENDSIE RITAYVIDTA HSRFPVIGED


 


101
KDEVLGILHA KDLLKYMFNP EQFHLKSILR PAVFVPEGKS LTALLKEFRE


 


151
QRNHMAIVID EYGGTSGLVT FEDIIEQIVG EIEDEFDEDD SADNIHAVSS


 


201
ERWRIHAATE IEDINTFFGT EYSXEEADTI GGLVIQELGH LPVRGEKVLI


 


251
GGLQFTVARA DNRRLHTLMA TRVK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 973 shows 95.6% identity over a 274 aa overlap with a predicted ORF (ORF 973.ng) from N. gonorrhoeae:





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2953>:










a973.seq




1
ATGGACGGCG CACAACCGAA AACAAATTTT TTTGAACGCC TGATTGCCCG


 


51
ACTCGCCCGC GAACCCGATT CCGCCGAAGA CGTATTGACC CTGTTGCGCC


 


101
AAGCGCACGA ACAGGAAGTA TTTGATGCGG ATACGCTTTT AAGATTGGAA


 


151
AAAGTCCTCG ATTTTTCTGA TTTGGAAGTG CGCGACGCGA TGATTACGCG


 


201
CAGCCGTATG AACGTTTTAA AAGAAAACGA CAGCATCGAA CGCATCACCG


 


251
CCTACGTTAT CGATACCGCC CATTCGCGCT TCCCCGTCAT CGGTGAAGAC


 


301
AAAGACGAAG TTTTGGGTAT TTTGCACGCC AAAGACCTGC TCAAATATAT


 


351
GTTCAACCCC GAGCAGTTCC ACCTCAAATC GATATTGCGC CCTGCCGTCT


 


401
TCGTCCCCGA AGGCAAATCG CTGACCGCCC TTTTAAAAGA GTTCCGCGAA


 


451
CAGCGCAACC ATATGGCAAT CGTCATCGAC GAATACGGCG GCACGTCGGG


 


501
TTTGGTAACT TTTGAAGACA TCATCGAGCA AATCGTCGGC GACATCGAAG


 


551
ATGAGTTTGA CGAAGACGAA AGCGCGGACA ACATCCACGC CGTTTCCGCC


 


601
GAACGCTGGC GCATCCACGC GGCTACCGAA ATCGAAGACA TCAACGCCTT


 


651
TTTCGGCACG GAATACAGCA GCGAAGAAGC CGACACCATC GGCGGCCTGG


 


701
TCATTCAGGA ATTGGGACAC CTGCCCGTGC GCGGCGAAAA AGTCCTTATC


 


751
GGCGGTTTGC AGTTCACCGT CGCCCGCGCC GACAACCGCC GCCTGCATAC


 


801
GCTGATGGCG ACCCGCGTGA AGTAA






This corresponds to the amino acid sequence <SEQ ID 2954; ORF 973.a>:










a973.pep




1
MDGAQPKTNF FERLIARLAR EPDSAEDVLT LLRQAHEQEV FDADTLLRLE


 


51
KVLDFSDLEV RDAMITRSRM NVLKENDSIE RITAYVIDTA HSRFPVIGED


 


101
KDEVLGILHA KDLLKYMFNP EQFHLKSILR PAVFVPEGKS LTALLKEFRE


 


151
QRNHMAIVID EYGGTSGLVT FEDIIEQIVG DIEDEFDEDE SADNIHAVSA


 


201
ERWRIHAATE IEDINAFFGT EYSSEEADTI GGLVIQELGH LPVRGEKVLI


 


251
GGLQFTVARA DNRRLHTLMA TRVK*






m973/a973 97.8% identity in 274 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2955>:










g981.seq




1
ATGAAAAAAT GGATTGCCGC CGCCCTTGCC TGTTCCGCAC TCGCGCTGTC


 


51
TGCCTGCGGC GGTCAGGGCA AAGATGCCGC CGCGCCTGCC GCCAACCCCG


 


101
GCAAAGTGTA CCGCGTGGCT TCCAACGCCG AGTTTGCCCC CTTTGAATCT


 


151
TTAGACTCGA AAGGCAATGT CGAAGGTTTC GACGTGGATT TGATGAACGC


 


201
GATGGCGAAG GCGGGCAATT TTAAAATCGA ATTCAAACAC CAGCCGTGGG


 


251
ACAGCCTTTT CCCCGCCTTG AACAACGGCG ATGCGGACGT TGTGATGTCG


 


301
GGCGTAACCA TTACCGACGA CCGCAAACAG TCTATGGATT TCAGCGACCC


 


351
GTATTTTGAA ATCACCCAAG TCGTCCTCGT TCCGAAAGGC AAAAAAGTAT


 


401
CTTCTTCCGA AGATTTGAAA AAGATGAACA AAGTCGGCGT GGTTACCGGC


 


451
CACACGGGCG ATTTCTCCGT TTCCAAACTC TTGGGCAACG ACAATCCGAA


 


501
AATCGCGCGC TTCGAAAACG TCCCCCTGAT TATCAAAGAA CTGGAAAACG


 


551
GCGGCTTGGA TTCCGTGGTC AGCGACAGCG CGGTCATCGC CAATTATGTG


 


601
AAAAACAACC CGGCCAAAGG AATGGACTTC GTTACCCTGC CCGACTTCAC


 


651
CACCGAACAC TACGGCATCG CGGTACGCAA AGGCGACGAA GCAACCGTCA


 


701
AAATGCTGAA CGATGCGTTG GAAAAAGTAC GCGAAAGCGG CGAATACGAC


 


751
AAGATCTACG CCAAATATTT TGCCAAAGAG GGCGGACAGG CTGCGAAATA


 


801
A






This corresponds to the amino acid sequence <SEQ ID 2956; ORF 981.ng>:










g981.pep




1
MKKWIAAALA CSALALSACG GQGKDAAAPA ANPGKVYRVA SNAEFAPFES


 


51
LDSKGNVEGF DVDLMNAMAK AGNFKIEFKH QPWDSLFPAL NNGDADVVMS


 


101
GVTITDDRKQ SMDFSDPYFE ITQVVLVPKG KKVSSSEDLK KMNKVGVVTG


 


151
HTGDFSVSKL LGNDNPKIAR FENVPLIIKE LENGGLDSVV SDSAVIANYV


 


201
KNNPAKGMDF VTLPDFTTEH YGIAVRKGDE ATVKMLNDAL EKVRESGEYD


 


251
KIYAKYFAKE GGQAAK*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2957>:










m981.seq




1
ATGAAAAAAT GGATTGCCGC CGCCCTTGCC TGTTCCGCGC TCGCGCTGTC


 


51
TGCCTGCGGC GGTCAGGGCA AAGATACCGC CGCGCCTGCC GCCAACCCCG


 


101
ACAAAGTGTA CCGCGTGGCT TCCAACGCCG AGTTTGCCCC CTTTGAATCT


 


151
TTAGACTCGA AAGGCAATGT CGAAGGTTTC GATGTGGATT TGATGAACGC


 


201
GATGGCGAAG GCGGGCAATT TTAAAATCGA ATTCAAACAC CAGCCGTGGG


 


251
ACAGCCTTTT CCCCGCCTTA AACAACGGCG ATGCGGACGT TGTGATGTCG


 


301
GGCGTAACCA TTACCGACGA CCGCAAACAG TCTATGGACT TCAGCGACCC


 


351
GTATTTTGAA ATCACCCAAG TCGTCCTCGT TCCGAAAGGC AAAAAAGTAT


 


401
CTTCTTCCGA AGATTTGAAA AACATGAACA AAGTCGGCGT GGTAACCGGC


 


451
TACACGGGCG ATTTCTCCGT ATCCAAACTC TTGGGCAACG ACAATCCGAA


 


501
AATCGCGCGC TTTGAAAACG TTCCCCTGAT TATCAAAGAA CTGGAAAACG


 


551
GCGGCTTGGA TTCCGTGGTC AGCGACAGCG CGGTCATCGC CAATTATGTG


 


601
AAAAACAATC CGGCCAAAGG GATGGACTTC GTTACCCTGC CCGACTTCAC


 


651
CACCGAACAC TACGGCATCG CGGTACGCAA AGGCGACGAA GCAACCGTCA


 


701
AAATGCTGAA CGATGCGTTG GAAAAAGTAC GCGAAAGCGG CGAATACGAC


 


751
AAGATTTACG CCAAATATTT TGCAAAAGAA GACGGACAGG CCGCAAAATA


 


801
A






This corresponds to the amino acid sequence <SEQ ID 2958; ORF 981>:










m981.pep




1
MKKWIAAALA CSALALSACG GQGKDTAAPA ANPDKVYRVA SNAEFAPFES


 


51
LDSKGNVEGF DVDLMNAMAK AGNFKIEFKH QPWDSLFPAL NNGDADVVMS


 


101
GVTITDDRKQ SMDFSDPYFE ITQVVLVPKG KKVSSSEDLK NMNKVGVVTG


 


151
YTGDFSVSKL LGNDNPKIAR FENVPLIIKE LENGGLDSVV SDSAVIANYV


 


201
KNNPAKGMDF VTLPDFTTEH YGIAVRKGDE ATVKMLNDAL EKVRESGEYD


 


251
KIYAKYFAKE DGQAAK*






m981/g981 98.1% identity in 266 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2959>:










a981.seq




1
ATGAAAAAAT GGATTGCCGC CGCCCTTGCC TGTTCCGCGC TCGCGCTGTC


 


51
TGCCTGCGGC GGTCAGGGTA AAGATGCCGC CGCGCCCGCC GCAAATCCCG


 


101
ACAAAGTGTA CCGCGTGGCT TCCAACGCCG AGTTTGCCCC CTTTGAATCT


 


151
TTAGACTCGA AAGGCAATGT CGAAGGTTTC GATGTGGATT TGATGAACGC


 


201
GATGGCGAAG GCGGGCAATT TTAAAATCGA ATTCAAACAC CAGCCGTGGG


 


251
ACAGCCTTTT CCCCGCCTTG AACAACGGCG ATGCGGACGT TGTGATGTCG


 


301
GGCGTAACCA TTACCGACGA CCGCAAACAG TCTATGGACT TCAGCGACCC


 


351
GTATTTTGAA ATCACCCAAG TCGTCCTCGT TCCGAAAGGC AAAAAAATAT


 


401
CTTCTTCCGA AGATTTGAAA AACATGAACA AAGTCGGCGT GGTAACCGGC


 


451
TACACGGGCG ATTTCTCCGT ATCCAAACTC TTGGGCAACG ACAACCCGAA


 


501
AATCGCGCGC TTTGAAAACG TTCCCCTGAT TATCAAAGAA CTGGAAAACG


 


551
GCGGCTTGGA TTCCGTGGTC AGCGACAGCG CAGTCATCGC CAATTATGTG


 


601
AAAAACAATC CGACCAAAGG GATGGACTTC GTTACCCTGC CCGACTTCAC


 


651
CACCGAACAC TACGGCATCG CGGTACGCAA AGGCGACGAA GCAACCGTCA


 


701
AAATGCTGAA CGATGCGTTG AAAAAAGTAC GCGAAAGCGG CGAATACGAC


 


751
AAAATCTACG CCAAATATTT TGCAAAAGAA GACGGACAGG CCGCAAAATA


 


801
A






This corresponds to the amino acid sequence <SEQ ID 2960; ORF 981.a>:










a981.pep




1
MKKWIAAALA CSALALSACG GQGKDAAAPA ANPDKVYRVA SNAEFAPFES


 


51
LDSKGNVEGF DVDLMNAMAK AGNFKIEFKH QPWDSLFPAL NNGDADVVMS


 


101
GVTITDDRKQ SMDFSDPYFE ITQVVLVPKG KKISSSEDLK NMNKVGVVTG


 


151
YTGDFSVSKL LGNDNPKIAR FENVPLIIKE LENGGLDSVV SDSAVIANYV


 


201
KNNPTKGMDF VTLPDFTTEH YGIAVRKGDE ATVKMLNDAL KKVRESGEYD


 


251
KIYAKYFAKE DGQAAK*






m981/a981 98.5% identity in 266 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2961>:










g982.seq




1
atcgcatcgc aaaaccttcg attcgacaat cgattcctcc aaaaaatggt


 


51
caacggcgTg aatattttgc cggccgcCga ttgggtagcC ttgGGcgcCA


 


101
AAGGCCGCAA CGTGGTGGTT GACCGCGCTT TCGGCGGCCC GCACATCACC


 


151
AAAGACGGCG TAACCGTCGC CAAAGAAATC GAACTGAAAG ACAAGTTTGA


 


201
AAATATGGGC GCGCAAATGG TAAAAGAAGT CGCGTCCAAA ACCAAcgaCg


 


251
tagCCGgcga cggtacgact accgCCACCG TATTGGCACA ATCCATCGTT


 


301
GCCGAAggcA TGAAATACGT TACCGCCGGC ATGAACCCGA CCGATCTGAA


 


351
ACGCGGCATC GACAAAGccg ttgCCGCTtt ggttgAAGAg cTGAAAAACA


 


401
TCGCCAAACC TTGCGATACT TCCAAAGAAA TCGCCCAAGT CGGCTCGATT


 


451
TCCGCCAACT CCGACGAACA AGtcgGCGCG ATTATCGCCG AAGCGATGGA


 


501
AAAAGTCGGC AAAGAAGgcg tgattacCGT TGAAGACGGC AAATCTTTGG


 


551
AAAACGAGCT GGACGTGGTT GAAGGTATGC AGTTCGACCG CGGCTACCTG


 


601
TCCCCTTACT TTATCAACGA CGCGGAAAAA CAAATCGCCG GTCTGGACAA


 


651
TCCGTTTGTT TTGCTGTTCG ACAAAAAAAT CAGCAACATC CGCGACCTGC


 


701
TGCCCGTGTT GGAACAAGTG GCGAAAGCCA GCCGCCCGCT GTTGATTATC


 


751
GCTGAAGACG TAGAAGGCGA AGCCTTGGCG ACTTTGGTCG TGAACAACAT


 


801
CCGCGGCATC CTGAAAACCG TTGCCGTCAA AGCccccggc tTCGGcGACC


 


851
GCCGCAAAGC GATgctgcaa gaCATCGCCA TCCTGACcgg cggcgTagtG


 


901
ATTtccGAAG Aagtcggcct GTCTTTGGAA AAAgcgactT TGgacgaCTT


 


951
Gggtcaaacc aaACGcatCG AAATCGGtga agaaaacact ACCGTCATcg


 


1001
acgGCTTCGG CGACGcagcC CAAAtcgaag cgCGTGTTGC CGAAATCCGC


 


1051
CAACAAATCG AAACCGCGAC CAGCGATTAC GACAAAGAAA AACTGCAAGA


 


1101
GCGCGTTGCC AAACTGGCAG GAGGCGTGGC AGTGATCAAA GTCGGCGCGG


 


1151
CGACCGAAGT CGAAATGAAA GAGAAAAAAG ACCGCGTGGA AGACGCGCTG


 


1201
CACGCTACCC GCGCAGCCGT TGAAGAAGGC GTGGTTGCAG GCGGCGGCGT


 


1251
AGCCCTGTTG CGCGCCCGTG CCGCTTTGGA AAACCTGCAC ACCGGCAATG


 


1301
CCGACCAAGA CGCAGGCGTA CAAATCGTAT TGCGCGCCGT TGAGTCTCCG


 


1351
CTGCGCCAAA TCGTTGCCAA CGCAGGCGGA GAACCCAGCG TGGTGGTGAA


 


1401
CAAAGTGTTG GAAGGCAAAG GCAactacgG TTACAACGCa ggctcCGGCG


 


1451
AATACGgcga CATGATCGGA ATGGGCGTAC TCGACCCTGC CAAAGTAACC


 


1501
CGTTCCGCGC TGCAACACGC CGCGTCTAtC GCCGGTCTGA TGCTGACGAC


 


1551
CGACTGCATG ATTGCCGAAA TCCCTGAAGA AAAACCGGCT GTGCCCGATA


 


1601
TGGGGGGAAT GGGCGGTATG GGCGGCATGA TGTAA






This corresponds to the amino acid sequence <SEQ ID 2962; ORF 982.ng>:










g982.pep




1
IASQNLRFDN RFLQKMVNGV NILPAADWVA LGAKGRNVVV DRAFGGPHIT


 


51
KDGVTVAKEI ELKDKFENMG AQMVKEVASK TNDVAGDGTT TATVLAQSIV


 


101
AEGMKYVTAG MNPTDLKRGI DKAVAALVEE LKNIAKPCDT SKEIAQVGSI


 


151
SANSDEQVGA IIAEAMEKVG KEGVITVEDG KSLENELDVV EGMQFDRGYL


 


201
SPYFINDAEK QIAGLDNPFV LLFDKKISNI RDLLPVLEQV AKASRPLLII


 


251
AEDVEGEALA TLVVNNIRGI LKTVAVKAPG FGDRRKAMLQ DIAILTGGVV


 


301
ISEEVGLSLE KATLDDLGQT KRIEIGEENT TVIDGFGDAA QIEARVAEIR


 


351
QQIETATSDY DKEKLQERVA KLAGGVAVIK VGAATEVEMK EKKDRVEDAL


 


401
HATRAAVEEG VVAGGGVALL RARAALENLH TGNADQDAGV QIVLRAVESP


 


451
LRQIVANAGG EPSVVVNKVL EGKGNYGYNA GSGEYGDMIG MGVLDPAKVT


 


501
RSALQHAASI AGLMLTTDCM IAEIPEEKPA VPDMGGMGGM GGMM*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2963>:










m982.seq




1
ATGGCAGCAA AAGACGTACA GTTCGGCAAT GAAGTCCGTC AAAAAATGGT


 


51
AAACGGCGTG AACATTCTGG CAAACGCCGT CCGCGTAACC TTGGGCCCCA


 


101
AAGGTCGCAA CGTAGTCGTT GACCGCGCAT TCGGCGGCCC GCACATCACC


 


151
AAAGACGGCG TAACCGTCGC CAAAGAAATC GAACTGAAAG ACAAGTTTGA


 


201
AAATATGGGC GCGCAAATGG TGAAAGAAGT TGCGTCCAAA ACCAACGACG


 


251
TGGCAGGCGA CGGTACGACT ACCGCCACCG TACTGGCGCA ATCCATCGTT


 


301
GCCGAAGGTA TGAAATATGT TACCGCAGGT ATGAATCCGA CCGACCTGAA


 


351
ACGCGGTATC GATAAAGCCG TCGCCGCTTT GGTTGACGAA CTGAAAAACA


 


401
TCGCCAAACC TTGCGACACT TCTAAAGAAA TCGCCCAAGT CGGCTCTATT


 


451
TCCGCCAACT CCGACGAACA AGTCGGCGCG ATTATCGCCG AAGCGATGGA


 


501
AAAAGTCGGC AAAGAAGGCG TGATTACCGT TGAAGACGGC AAGTCTTTGG


 


551
AAAACGAGCT GGACGTAGTT GAAGGTATGC AGTTCGACCG CGGCTACCTG


 


601
TCTCCTTACT TCATCAACGA TGCGGAAAAA CAAATCGCTG CTTTGGACAA


 


651
TCCGTTTGTA TTGTTGTTCG ACAAAAAAAT CAGCAACATC CGCGACCTGC


 


701
TGCCTGTTTT GGAACAAGTG GCAAAAGCCA GCCGTCCGCT GTTGATTATC


 


751
GCTGAAGACG TAGAAGGCGA AGCCTTGGCG ACTTTGGTCG TGAACAACAT


 


801
CCGAGGCATC CTGAAAACCG TTGCCGTCAA AGCCCCTGGC TTCGGCGACC


 


851
GCCGCAAAGC GATGTTGCAA GACATCGCCA TCCTGACCGG CGGCGTGGTG


 


901
ATTTCCGAAG AAGTCGGTCT GTCTTTGGAA AAAGCGACTT TGGACGACTT


 


951
GGGTCAAGCC AAACGCATCG AAATCGGTAA AGAAAACACC ACCATCATCG


 


1001
ACGGCTTTGG CGACGCAGCC CAAATCGAAG CGCGTGTTGC CGAAATCCGC


 


1051
CAACAAATCG AAACCGCAAC CAGCGATTAC GACAAAGAAA AACTGCAAGA


 


1101
GCGCGTGGCT AAATTGGCAG GCGGCGTGGC AGTCATCAAA GTCGGTGCCG


 


1151
CGACCGAAGT CGAAATGAAA GAGAAAAAAG ACCGCGTGGA AGACGCGCTG


 


1201
CACGCTACCC GCGCAGCCGT TGAAGAAGGC GTGGTTGCAG GCGGCGGCGT


 


1251
AGCCCTGTTG CGTGCCCGTG CTGCTTTGGA AAACCTGCAC ACCGGCAATG


 


1301
CCGACCAAGA CGCAGGCGTA CAAATCGTCT TGCGCGCCGT TGAGTCTCCG


 


1351
CTGCGCCAAA TCGTTGCCAA CGCAGGCGGC GAACCCAGCG TGGTTGTGAA


 


1401
CAAAGTATTG GAAGGCAAAG GCAACTACGG TTACAACGCT GGCAGCGGCG


 


1451
AATACGGCGA TATGATCGAA ATGGGCGTAC TCGACCCCGC CAAAGTAACC


 


1501
CGTTCTGCGC TGCAACACGC CGCATCTATC GCCGGCTTGA TGCTGACCAC


 


1551
TGATTGCATG ATCGCTGAAA TCCCCGAAGA CAAACCGGCT GTGCCTGATA


 


1601
TGGGCGGCAT GGGTGGTATG GGCGGCATGA TGTAA






This corresponds to the amino acid sequence <SEQ ID 2964; ORF 982>:










m982.seq




1
ATGGCAGCAA AAGACGTACA GTTCGGCAAT GAAGTCCGTC AAAAAATGGT


 


51
AAACGGCGTG AACATTCTGG CAAACGCCGT CCGCGTAACC TTGGGCCCCA


 


101
AAGGTCGCAA CGTAGTCGTT GACCGCGCAT TCGGCGGCCC GCACATCACC


 


151
AAAGACGGCG TAACCGTCGC CAAAGAAATC GAACTGAAAG ACAAGTTTGA


 


201
AAATATGGGC GCGCAAATGG TGAAAGAAGT TGCGTCCAAA ACCAACGACG


 


251
TGGCAGGCGA CGGTACGACT ACCGCCACCG TACTGGCGCA ATCCATCGTT


 


301
GCCGAAGGTA TGAAATATGT TACCGCAGGT ATGAATCCGA CCGACCTGAA


 


351
ACGCGGTATC GATAAAGCCG TCGCCGCTTT GGTTGACGAA CTGAAAAACA


 


401
TCGCCAAACC TTGCGACACT TCTAAAGAAA TCGCCCAAGT CGGCTCTATT


 


451
TCCGCCAACT CCGACGAACA AGTCGGCGCG ATTATCGCCG AAGCGATGGA


 


501
AAAAGTCGGC AAAGAAGGCG TGATTACCGT TGAAGACGGC AAGTCTTTGG


 


551
AAAACGAGCT GGACGTAGTT GAAGGTATGC AGTTCGACCG CGGCTACCTG


 


601
TCTCCTTACT TCATCAACGA TGCGGAAAAA CAAATCGCTG CTTTGGACAA


 


651
TCCGTTTGTA TTGTTGTTCG ACAAAAAAAT CAGCAACATC CGCGACCTGC


 


701
TGCCTGTTTT GGAACAAGTG GCAAAAGCCA GCCGTCCGCT GTTGATTATC


 


751
GCTGAAGACG TAGAAGGCGA AGCCTTGGCG ACTTTGGTCG TGAACAACAT


 


801
CCGAGGCATC CTGAAAACCG TTGCCGTCAA AGCCCCTGGC TTCGGCGACC


 


851
GCCGCAAAGC GATGTTGCAA GACATCGCCA TCCTGACCGG CGGCGTGGTG


 


901
ATTTCCGAAG AAGTCGGTCT GTCTTTGGAA AAAGCGACTT TGGACGACTT


 


951
GGGTCAAGCC AAACGCATCG AAATCGGTAA AGAAAACACC ACCATCATCG


 


1001
ACGGCTTTGG CGACGCAGCC CAAATCGAAG CGCGTGTTGC CGAAATCCGC


 


1051
CAACAAATCG AAACCGCAAC CAGCGATTAC GACAAAGAAA AACTGCAAGA


 


1101
GCGCGTGGCT AAATTGGCAG GCGGCGTGGC AGTCATCAAA GTCGGTGCCG


 


1151
CGACCGAAGT CGAAATGAAA GAGAAAAAAG ACCGCGTGGA AGACGCGCTG


 


1201
CACGCTACCC GCGCAGCCGT TGAAGAAGGC GTGGTTGCAG GCGGCGGCGT


 


1251
AGCCCTGTTG CGTGCCCGTG CTGCTTTGGA AAACCTGCAC ACCGGCAATG


 


1301
CCGACCAAGA CGCAGGCGTA CAAATCGTCT TGCGCGCCGT TGAGTCTCCG


 


1351
CTGCGCCAAA TCGTTGCCAA CGCAGGCGGC GAACCCAGCG TGGTTGTGAA


 


1401
CAAAGTATTG GAAGGCAAAG GCAACTACGG TTACAACGCT GGCAGCGGCG


 


1451
AATACGGCGA TATGATCGAA ATGGGCGTAC TCGACCCCGC CAAAGTAACC


 


1501
CGTTCTGCGC TGCAACACGC CGCATCTATC GCCGGCTTGA TGCTGACCAC


 


1551
TGATTGCATG ATCGCTGAAA TCCCCGAAGA CAAACCGGCT GTGCCTGATA


 


1601
TGGGCGGCAT GGGTGGTATG GGCGGCATGA TGTAA






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m982/g982 95.8% identity in 544 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2965>:










a982.seq




1
ATGGCAGCAA AAGACGTACA ATTCGGCAAT GAAGTCCGCC AAAAAATGGT


 


51
AAACGGCGTG AACATTTTGG CAAACGCCGT GCGCGTAACC TTGGGTCCCA


 


101
AAGGCCGCAA CGTGGTGGTT GACCGCGCTT TCGGCGGCCC GCACATCACC


 


151
AAAGACGGCG TAACCGTCGC CAAAGAAATC GAACTGAAAG ACAAGTTTGA


 


201
AAATATGGGC GCGCAAATGG TGAAAGAAGT CGCGTCCAAA ACCAACGACG


 


251
TGGCGGGCGA CGGTACGACT ACCGCCACCG TATTGGCGCA ATCCATCGTT


 


301
GCCGAAGGTA TGAAATACGT TACCGCCGGT ATGAACCCGA CCGACCTGAA


 


351
ACGCGGTATC GACAAAGCCG TCGCCGCTTT GGTTGAAGAG CTGAAAAACA


 


401
TCGCCAAACC TTGCGACACT TCTAAAGAAA TCGCCCAAGT CGGCTCTATT


 


451
TCCGCCAACT CTGACGAACA AGTCGGCGCG ATTATTGCCG AAGCGATGGA


 


501
AAAAGTCGGC AAAGAAGGCG TGATTACCGT TGAAGACGGC AAATCTTTGG


 


551
AAAACGAGCT GGACGTGGTT GAAGGTATGC AATTCGACCG CGGCTACCTG


 


601
TCTCCTTACT TCATCAACGA TGCGGAAAAA CAAATCGCCG GCTTGGACAA


 


651
TCCGTTTGTA TTGCTGTTCG ACAAAAAAAT CAGCAATATC CGCGACCTGC


 


701
TGCCTGTTTT GGAACAAGTG GCCAAAGCCA GCCGTCCGCT GTTGATTATC


 


751
GCTGAAGACG TAGAAGGCGA AGCCTTGGCG ACTTTGGTCG TGAACAACAT


 


801
CCGCGGCATT CTGAAAACCG TTGCCGTTAA AGCTCCGGGC TTCGGCGACC


 


851
GCCGCAAAGC GATGCTGCAA GACATCGCTA TCCTGACCGG CGGCACAGTG


 


901
ATTTCCGAAG AAGTCGGCCT GTCTTTGGAA AAAGCGACTT TGGACGACTT


 


951
GGGTCAGGCC AAACGCATCG AAATCGGTAA AGAAAACACC ACCATCATCG


 


1001
ACGGCTTCGG CGACGCAGCC CAAATCGAAG CGCGTGTTGC CGAAATCCGC


 


1051
CAACAAATCG AAACCGCAAC CAGCGATTAC GACAAAGAAA AACTGCAAGA


 


1101
GCGCGTTGCC AAACTGGCAG GCGGCGTGGC AGTAATCAAA GTCGGTGCCG


 


1151
CGACCGAAGT GGAAATGAAA GAGAAAAAAG ACCGCGTGGA AGACGCGCTG


 


1201
CACGCTACCC GCGCAGCCGT TGAAGAAGGC GTGGTTGCAG GCGGCGGCGT


 


1251
AGCCCTGTTG CGCGCCCGTG CCGCTCTGGA AAACCTGCAC ACCGGCAATG


 


1301
CAGACCAAGA CGCAGGCGTA CAAATCGTCT TGCGCGCCGT TGAGTCTCCG


 


1351
CTGCGCCAAA TCGTTGCCAA CGCAGGCGGC GAACCCAGCG TGGTTGTGAA


 


1401
CAAAGTGTTG GAAGGCAAAG GCAACTATGG TTACAACGCT GGCAGCGGCG


 


1451
AATACGGCGA CATGATCGAA ATGGGCGTAC TCGACCCCGC CAAAGTAACC


 


1501
CGTTCCGCGC TGCAACACGC CGCGTCTATC GCCGGCCTGA TGCTGACCAC


 


1551
AGACTGCATG ATTGCTGAAA TCCCTGAAGA CAAACCGGCT ATGCCTGATA


 


1601
TGGGCGGCAT GGGTGGTATG GGCGGCATGA TGTAA






This corresponds to the amino acid sequence <SEQ ID 2966; ORF 982.a>:










a982.pep




1
MAAKDVQFGN EVRQKMVNGV NILANAVRVT LGPKGRNVVV DRAFGGPHIT


 


51
KDGVTVAKEI ELKDKFENMG AQMVKEVASK TNDVAGDGTT TATVLAQSIV


 


101
AEGMKYVTAG MNPTDLKRGI DKAVAALVEE LKNIAKPCDT SKEIAQVGSI


 


151
SANSDEQVGA IIAEAMEKVG KEGVITVEDG KSLENELDVV EGMQFDRGYL


 


201
SPYFINDAEK QIAGLDNPFV LLFDKKISNI RDLLPVLEQV AKASRPLLII


 


251
AEDVEGEALA TLVVNNIRGI LKTVAVKAPG FGDRRKAMLQ DIAILTGGTV


 


301
ISEEVGLSLE KATLDDLGQA KRIEIGKENT TIIDGFGDAA QIEARVAEIR


 


351
QQIETATSDY DKEKLQERVA KLAGGVAVIK VGAATEVEMK EKKDRVEDAL


 


401
HATRAAVEEG VVAGGGVALL RARAALENLH TGNADQDAGV QIVLRAVESP


 


451
LRQIVANAGG EPSVVVNKVL EGKGNYGYNA GSGEYGDMIE MGVLDPAKVT


 


501
RSALQHAASI AGLMLTTDCM IAEIPEDKPA MPDMGGMGGM GGMM*






m982/a982 99.3% identity in 544 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2967>:










g986.seq




1
GTGTTCAAAA AATACCAATA CTTCGCTTTG GCGGCACTGT GTGCCGCCTT


 


51
GCTGGCAGGC TGCGAAAAGG CAGGCAGCTT TTTCGGTGCG GACAAAAAAG


 


101
AAGCATCCTT CGTAGAACGC ATCGAACACA CCAAAGACGA CGGCAGTGTC


 


151
AGTATGCTGC TGCCCGACTT TGCCCAACTG GTTCAAAGCG AAGGCCCGGC


 


201
AGTCGTCAAT ATTCAGGCAG CCCCCGCCCC GCGCACCCAA AACGGCAGCG


 


251
GCAATGCCGA AACCGATTCC GACCCGCTTG CCGACAGCGA CCCGTTCTAC


 


301
GAATTTTTCA AACGCCTCGT CCCGAACATG CCCGAAATCC CCCAAGAAGA


 


351
AGCAGATGAC GGCGGATTGA ACTTCGGTTC GGGCTTCATC ATCAGCAAAA


 


401
ACGGCTACAT CCTGACCAAT ACCCACGTCG TTGCCGGTAT GGGCAGTATC


 


451
AAAGTCCTGC TCAACGACAA GCGCGAATAT ACCGCCAAAC TCATCGGTTC


 


501
GGATGTCCAA TCCGATGTCG CCCTTCTGAA AATCGACGCA ACGGAAGAGC


 


551
TACCCGTCGT CAAAATCGGC AATCCCAAAA ATTTGAAACC GGGCGAATGG


 


601
GTCGCTGCCA TCGGCGCGCC CTTCGGCTTT GACAACAGCG TGACCGCCGG


 


651
CATCGTGTCC GCCAAAGGCA GAAGCCTGCC CAACGAAAgc tACACACCCT


 


701
TCATCCAAAC CGACGTTGCC ATCAATCCGG GCAATTCCGG CGGCCCGCTG


 


751
TTCAACTTAA AAGGACAGGt cgTCGGCATC AATTCGCAAA TATACAGCCG


 


801
CAGCGgcgga ttCATGGGCA TCTCCTTTGC CATCCCGATT GACGTTGCCA


 


851
TGAATGTCGC CGAACAGCTG AAAAACACCG GCAAAGTCCA ACGCGGACAA


 


901
CTGGGCGTGA TTATTCAGGA AGTATCCTAC GGTTTGGCAC AGTCGTTCGG


 


951
TCTGGATAAA GCCAGCGGCG CATTGATTGC CAAAATCCTT CCCGGCAGCC


 


1001
CCGCAGAACG TGCCGGCCTG CAGGCGGGCG ACATCGTCCT CAGCCTCGAC


 


1051
GGCGGAGAAA TACGTTCTTC CGGCGACCTT CCCGTCATGG TCGGCGCCAT


 


1101
TACGCCGGGA AAAGAAGTCA GCCTCGGCGT ATGGCGCAAA GGCGAAGAAA


 


1151
TCACAATCAA AGCCAAGCTG GGCAACGCCg ccgagcATAC CGGCgcatCA


 


1201
TCCAAAACAG ATGAAgcccc ctacaccgAA CAGCAATCCG GTACGTTCTC


 


1251
GGTCGAATCC GCAGGCATTA CCCTTCAGAC ACATACCGAC AGCAGCGGca


 


1301
aacacctcgt cgtcgtacgg gtttccgacg cggcagaacg cGCAGGCTTA


 


1351
AGgcgcggcg acgaaatcct cgcggtcggg caagtccccg tcaatgacga


 


1401
agccgGTTTC cgcaaaGCTA TGGACAAGGC AGGCAAAAAC GTCCCCCTGC


 


1451
TGGTCAtgcg ccgTGGCAAC ACGCTGTTCA TCGCATTAAA CCTGCAATAA






This corresponds to the amino acid sequence <SEQ ID 2968; ORF 986.ng>:










g986.pep




1
VFKKYQYFAL AALCAALLAG CEKAGSFFGA DKKEASFVER IEHTKDDGSV


 


51
SMLLPDFAQL VQSEGPAVVN IQAAPAPRTQ NGSGNAETDS DPLADSDPFY


 


101
EFFKRLVPNM PEIPQEEADD GGLNFGSGFI ISKNGYILTN THVVAGMGSI


 


151
KVLLNDKREY TAKLIGSDVQ SDVALLKIDA TEELPVVKIG NPKNLKPGEW


 


201
VAAIGAPFGF DNSVTAGIVS AKGRSLPNES YTPFIQTDVA INPGNSGGPL


 


251
FNLKGQVVGI NSQIYSRSGG FMGISFAIPI DVAMNVAEQL KNTGKVQRGQ


 


301
LGVIIQEVSY GLAQSFGLDK ASGALIAKIL PGSPAERAGL QAGDIVLSLD


 


351
GGEIRSSGDL PVMVGAITPG KEVSLGVWRK GEEITIKAKL GNAAEHTGAS


 


401
SKTDEAPYTE QQSGTFSVES AGITLQTHTD SSGKHLVVVR VSDAAERAGL


 


451
RRGDEILAVG QVPVNDEAGF RKAMDKAGKN VPLLVMRRGN TLFIALNLQ*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2969>:










m986.seq




1
GTGTTCAAAA AATACCAATA CCTCGCTTTG GCAGCACTGT GTGCAGCCTC


 


51
GCTGGCAGGC TGCGACAAGG CAGGCAGCTT CTTCGTGGCG GACAAAAAAG


 


101
AAGCATCCTT CGTAGAACGC ATCGAACACA CCAAAGACGA CGGCAGCGTC


 


151
AGTATGCTGC TGCCCGACTT TGCCCAACTG GTTCAAAGTG AAGGTCCGGC


 


201
AGTCGTCAAT ATTCAGGCAG CCCCCGCCCC GCGCACCCAA AACGGCAGCG


 


251
GCAATGCCGA AAACGATTCC GACCCGATTG CCGACAACGA CCCGTTCTAC


 


301
GAATTTTTCA AACGCCTCGT CCCGAATATG CCCGAAATCC CCCAAGAAGA


 


351
AGCAGATGAC GGCGGATTGA ACTTCGGTTC GGGCTTCATC ATCAGCAAAG


 


401
ACGGCTACAT CCTGACCAAT ACCCACGTCG TTACCGGCAT GGGCAGTATC


 


451
AAAGTCCTGC TCAACGACAA GCGCGAATAT ACCGCCAAAC TCATCGGTTC


 


501
GGATGTCCAA TCCGATGTCG CCCTTCTGAA AATCGACGCA ACGGAAGAGC


 


551
TGCCCGTCGT CAAAATCGGC AATCCCAAAG ATTTGAAACC GGGCGAATGG


 


601
GTCGCCGCCA TCGGCGCGCC CTTCGGCTTC GACAACAGCG TGACCGCCGG


 


651
CATCGTGTCC GCCAAAGGCA GAAGCCTGCC CAACGAAAGC TACACACCCT


 


701
TCATCCAAAC CGACGTTGCC ATCAATCCGG GCAACTCCGG CGGCCCGCTG


 


751
TTCAACTTAA AAGGACAGGT CGTCGGCATC AACTCGCAAA TATACAGCCG


 


801
CAGCGGCGGA TTCATGGGCA TTTCCTTCGC CATCCCGATT GACGTTGCCA


 


851
TGAATGTCGC CGAACAGCTG AAAAACACCG GCAAAGTCCA ACGCGGACAA


 


901
CTGGGCGTGA TTATTCAAGA AGTATCCTAC GGTTTGGCAC AATCGTTCGG


 


951
TTTGGACAAA GCCGGCGGCG CACTGATTGC CAAAATCCTG CCCGGCAGCC


 


1001
CCGCAGAACG TGCCGGCCTG CAGGCGGGCG ACATCGTCCT CAGCCTCGAC


 


1051
GGCGGAGAAA TACGTTCTTC CGGCGACCTT CCCGTTATGG TCGGCGCCAT


 


1101
TACGCCGGGA AAAGAAGTCA GCCTCGGCGT ATGGCGCAAA GGCGAAGAAA


 


1151
TCACAATCAA AGTCAAGCTG GGCAACGCCG CCGAGCATAT CGGCGCATCA


 


1201
TCCAAAACAG ATGAAGCCCC CTACACCGAA CAGCAATCCG GTACGTTCTC


 


1251
GGTCGAATCC GCAGGCATTA CCCTTCAGAC ACATACCGAC AGCAGCGGCG


 


1301
GACACCTCGT CGTCGTACGG GTTTCCGACG CGGCAGAACG CGCAGGCTTG


 


1351
AGGCGCGGCG ACGAAATTCT TGCCGTCGGG CAAGTCCCCG TCAATGACGA


 


1401
AGCCGGTTTC CGCAAAGCTA TGGACAAGGC AGGCAAAAAC GTCCCCCTGC


 


1451
TGATCATGCG CCGTGGCAAC ACGCTGTTTA TCGCATTAAA CCTGCAATAA






This corresponds to the amino acid sequence <SEQ ID 2970; ORF 986>:










m986.pep..




1
VFKKYQYLAL AALCAASLAG CDKAGSFFVA DKKEASFVER IEHTKDDGSV


 


51
SMLLPDFAQL VQSEGPAVVN IQAAPAPRTQ NGSGNAENDS DPIADNDPFY


 


101
EFFKRLVPNM PEIPQEEADD GGLNFGSGFI ISKDGYILTN THVVTGMGSI


 


151
KVLLNDKREY TAKLIGSDVQ SDVALLKIDA TEELPVVKIG NPKDLKPGEW


 


201
VAAIGAPFGF DNSVTAGIVS AKGRSLPNES YTPFIQTDVA INPGNSGGPL


 


251
FNLKGQVVGI NSQIYSRSGG FMGISFAIPI DVAMNVAEQL KNTGKVQRGQ


 


301
LGVIIQEVSY GLAQSFGLDK AGGALIAKIL PGSPAERAGL QAGDIVLSLD


 


351
GGEIRSSGDL PVMVGAITPG KEVSLGVWRK GEEITIKVKL GNAAEHIGAS


 


401
SKTDEAPYTE QQSGTFSVES AGITLQTHTD SSGGHLVVVR VSDAAERAGL


 


451
RRGDEILAVG QVPVNDEAGF RKAMDKAGKN VPLLIMRRGN TLFIALNLQ*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m986/g986 97.0% identity in 499 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2971>:










a986.seq




1
GTGTTCAAAA AATACCAATA CCTCGCTTTG GCAGCACTGT GTGCCGCCTC


 


51
GCTGGCAGGC TGCGACAAAG CCGGCAGCTT TTTCGGTGCG GACAAAAAAG


 


101
AAGCATCCTT TGTAGAACGC ATCAAACACA CCAAAGACGA CGGCAGCGTC


 


151
AGTATGCTGC TGCCCGACTT TGTCCAACTG GTTCAAAGCG AAGGCCCGGC


 


201
AGTCGTCAAT ATTCAGGCAG CCCCCGCCCC GCGCACCCAA AACGGCAGCA


 


251
GCAATGCCGA AACCGATTCC GACCCGCTTG CCGACAGCGA CCCGTTCTAC


 


301
GAATTTTTCA AACGCCTCGT CCCGAACATG CCCGAAATCC CCCAAGAAGA


 


351
AGCAGATGAC GGNGGATTGA ACTTCGGTTC GGGCTTCATC ATCAGCAAAG


 


401
ACGGCTATAT TCTGACCAAT ACGCACGTCG TTACCGGCAT GGGCAGTATC


 


451
AAAGTCCTGC TCAACGACAA GCGCGAATAT ACCGCCAAAC TCATCGGTTC


 


501
GGATGTCCAA TCCGATGTCG CCCTTCTGAA AATCGACGCA ACGGAAGAGC


 


551
TGCCCGTCGT CAAAATCGGC AATCCCAAAG ATTTGAAACC GGGCGAATGG


 


601
GTCGCCGCCA TCGGCGCGCC CTTCGGCTTC GACAACAGCG TGACCGCCGG


 


651
CNTCGTGTCC GCCAAAGGCA GAAGCCTGCC CAACGAAAGC TACACACCCT


 


701
TCATCCAAAC CGACGTTGCC ATCAATCCGG GCAACTCCGG CGGCCCGCTG


 


751
TTCAACTTAA AAGGACAGGT CGTCGGCATC AACTCGCAAA TATACAGCCG


 


801
CAGCGGCGGA TTCATGGGCA TTTCCTTCGC CATCCCGATT GACGTTGCCA


 


851
TGAATGTCGC CGAACAGCTG AAAAACACCG GCAAAGTCCA ACGCGGACAA


 


901
CTGGGCGTGA TTATTCAAGA AGTATCCTAC GGTTTGGCAC AATCGTTCGG


 


951
TTTGGACAAA GCCGGCGGCG CACTGATTGC CAAAATCCTG CCCGGCAGCC


 


1001
CCGCAGAACG TGCCGGCCTG CGGGCGGGCG ACATCGTCCT CAGCCTCGAC


 


1051
GGCGGAGAAA TACGTTCTTC CGGCGACCTT CCCGTTATGG TCGGCGCCAT


 


1101
TACGCCGGGA AAAGAAGTCA GCCTCGGCGT ATGGCGCAAA GGCGAAGAAA


 


1151
TCACAATCAA AGTCAAGCTG GGCAACGCCG CCGAGCATAT CGGCGCATCA


 


1201
TCCAAAACAG ATGAAGCCCC CTACACCGAA CAGCAATCCG GTACGTTCTC


 


1251
GGTCGAATCC GCAGGCATTA CCCTTCAGAC ACATACCGAC AGCAGCGGCG


 


1301
GACACCTCGT CGTCGTACGG GTTTCCGACG CGGCAGAACG CGCAGGCTTG


 


1351
AGGCGCGGCG ACGAAATTCT TGCCGTCGGG CAAGTCCCCG TCAATGACGA


 


1401
AGCCGGTTTC CGCAAAGCTA TGGACAAGGC AGGCAAAAAC GTCCCCCTGC


 


1451
TGATCATGCG CCGTGGCAAC ACGCTGTTTA TCGCATTAAA CCTGCAATAA






This corresponds to the amino acid sequence <SEQ ID 2972; ORF 986.a>:










a986.pep




1
VFKKYQYLAL AALCAASLAG CDKAGSFFGA DKKEASFVER IKHTKDDGSV


 


51
SMLLPDFVQL VQSEGPAVVN IQAAPAPRTQ NGSSNAETDS DPLADSDPFY


 


101
EFFKRLVPNM PEIPQEEADD GGLNFGSGFI ISKDGYILTN THVVTGMGSI


 


151
KVLLNDKREY TAKLIGSDVQ SDVALLKIDA TEELPVVKIG NPKDLKPGEW


 


201
VAAIGAPFGF DNSVTAGXVS AKGRSLPNES YTPFIQTDVA INPGNSGGPL


 


251
FNLKGQVVGI NSQIYSRSGG FMGISFAIPI DVAMNVAEQL KNTGKVQRGQ


 


301
LGVIIQEVSY GLAQSFGLDK AGGALIAKIL PGSPAERAGL RAGDIVLSLD


 


351
GGEIRSSGDL PVMVGAITPG KEVSLGVWRK GEEITIKVKL GNAAEHIGAS


 


401
SKTDEAPYTE QQSGTFSVES AGITLQTHTD SSGGHLVVVR VSDAAERAGL


 


451
RRGDEILAVG QVPVNDEAGF RKAMDKAGKN VPLLIMRRGN TLFIALNLQ*






m986/a986 98.2% identity in 499 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2973>:










g987.seq




1
ATGAAAACAC GCAGCCTCAT TTCCCTTTTA TGCCTCCTTC TCTGTTCATG


 


51
TTCTTCATGG TTGCCCCCAC TGGAAGAACG GACGGAAAGC CGTCATTTTA


 


101
ATACTTCCAA ACCTGTCCTC CTGGACAACA TCCTGCAAAT CCGGCACACC


 


151
CCTCATAACA ACGGGCTATC CGACATCTAC CTGCTCGACG ACCCCCACGA


 


201
AGCCTTTGCC GCCCGCGCCG CCCTTATCGA ATCTGCCGAA CACAGCCTCG


 


251
ATTTGCAATA CTACATTTGG CGCAACGaCA TTTCCGGCAG GCTGCTGTTC


 


301
AACCTCATGT ACCTTGCCGC agaacgcGGC GTGCGCGTAC GCCTGCTGTt


 


351
ggacgacaAC AACAcgcgcg gcttggacga tctcctGCTC GCCCTCGACA


 


401
GCCATCCCAA TAtctaagtG CGCCTGTTCA ACCCCTtcgt CCTACGCAAA


 


451
TGGCGCGCAC TCGGCTACCT GACCGACTTC CCCCGCCTCA ACCGCCGCAT


 


501
GCACAACAAA TCCTTTACCG CCGACAACCG CGCCACCATA CTCGGCGGAC


 


551
GCAATATCGG CGACGAATAC TTCAAAGTCG GTGAGGACAC CGTTTTCGCC


 


601
GACCTGGACA TCCTCGCCAC CGGCAGCGTC GTCGGCGAAG TATCGCACGA


 


651
CTTCGACCGC TACTGGGCAA GCCATTCCGC CCACAACGCC ACGCGCATCA


 


701
TCCGCAGCGG CAACATCGGC AAGGGTCTTC AAGCACTCGG ATACAACGAC


 


751
GAAACATCCA GACACGCGCT CCTGCGCTAC CGCGAAACCG TCGAACAGTC


 


801
GCCCCTCTAC CAAAAAATAC AGACGGGACG CATCGACTGG CAGAGCGTCC


 


851
AAACCCGCCT GATCAGCGAC AGCCCTGCAA AAGGACTCGA CCGCGACCGC


 


901
CGCAAACCGC CGATTGCCGG GAGGCTGCAA GACGCGCTCA AACAGCCCGA


 


951
AAAAAGCGTC TATCTGGTTT CACCCTATTT CGTCCCTACA AAATCCGGCA


 


1001
CAGACGCACT GGCAAAACTG GTGCAGGACG GCATAGACGT TACCGTCCTG


 


1051
ACCAACTCGC TACAGGCGAC CGACGTTGCC GCCGTCCATT CCGGCTACGT


 


1101
CAAATACCGA AAACCGCTGC TCAAAGCCGG CATCAAACTC TACGAGCTGC


 


1151
AACCCAACCA TGCCGTCCCC GCCACAAAAG ACAAAGGCCT GACCGGCAGC


 


1201
TCCGTAACCA GCCTGCATGC CAAAACCTTC ATTGTGGacg gCAAACGCAT


 


1251
CTTCATCGGC TCATTCAACC TCGACCCCCG TTCCGCACGG CTCAATACCG


 


1301
AAATGGGCGT CGTCATCGAA AGCCCCAAAA TCGCAGAACA GATGGAGCGC


 


1351
AccctCGCCG AtacCACACC CGAATACGCC TACCGCGTTA CCCTCGACAA


 


1401
ACACAACCGC CTGCAATGGC ACGATCCCGC CACCCGAAAA ACCTACCCGA


 


1451
ACGAACCCGA AGCCAAACTT TGGAAACGCA TCGCCGCAAA AATCCTATCC


 


1501
CTGCTGCCCA TCGAAGGTTT ATTATAG






This corresponds to the amino acid sequence <SEQ ID 2974; ORF 987.ng>:










g987.pep




1
MKTRSLISLL CLLLCSCSSW LPPLEERTES RHFNTSKPVL LDNILQIRHT


 


51
PHNNGLSDIY LLDDPHEAFA ARAALIESAE HSLDLQYYIW RNDISGRLLF


 


101
NLMYLAAERG VRVRLLLDDN NTRGLDDLLL ALDSHPNI*V RLFNPFVLRK


 


151
WRALGYLTDF PRLNRRMHNK SFTADNRATI LGGRNIGDEY FKVGEDTVFA


 


201
DLDILATGSV VGEVSHDFDR YWASHSAHNA TRIIRSGNIG KGLQALGYND


 


251
ETSRHALLRY RETVEQSPLY QKIQTGRIDW QSVQTRLISD SPAKGLDRDR


 


301
RKPPIAGRLQ DALKQPEKSV YLVSPYFVPT KSGTDALAKL VQDGIDVTVL


 


351
TNSLQATDVA AVHSGYVKYR KPLLKAGIKL YELQPNHAVP ATKDKGLTGS


 


401
SVTSLHAKTF IVDGKRIFIG SFNLDPRSAR LNTEMGVVIE SPKIAEQMER


 


451
TLADTTPEYA YRVTLDKHNR LQWHDPATRK TYPNEPEAKL WKRIAAKILS


 


501
LLPIEGLL*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2975>:










m987.seq




1
ATGAAAACAC GCAGCCTAAT TTCCCTTTTA TGCCTCCTTC TCTGTTCATG


 


51
TTCTTCATGG TTGCCCCCAC TGGAAGAACG GACGGAAAGC CGTCATTTCA


 


101
ATACTTCCAA ACCCGTCCGC CTGGACAACA TCCTGCAAAT CCGGCACACC


 


151
CCTCATACCA ACGGGCTATC CGATATCTAT CTGTTGAACG ACCCCCACGA


 


201
AGCCTTTGCC GCCCGCGCCG CCCTTATCGA ATCTGCCGAA CACAGCCTCG


 


251
ATTTGCAATA CTACATCTGG CGCAACGACA TTTCCGGCAG GCTGCTGTTC


 


301
AACCTCGTGT ACCTTGCCGC AGAACGCGGT GTGCGCGTAC GCCTGCTGTT


 


351
GGACGACAAC AACACGCGCG GATTGGACGA CCTCCTGCTT GCCCTCGACA


 


401
GCCATCCCAA TATCGAAGTG CGCCTGTTCA ACCCCTTCGT CTTACGAAAA


 


451
TGGCGCGCAC TCGGCTACCT GACCGACTTC CCCCGCCTCA ACCGCCGCAT


 


501
GCACAACAAA TCCTTTACCG CCGACAACCG CGCCACCATA CTCGGCGGAC


 


551
GCAATATCGG CGACGAATAC TTCAAAGTCG GTGAGGACAC CGTTTTCGCC


 


601
GATTTGGACA TCCTCGCCAC CGGCAGCGTC GTCGGCGAAG TATCGCACGA


 


651
CTTCGACCGC TACTGGGCAA GCCATTCCGC CCACAACGCC ACGCGCATCA


 


701
TCCGCAGCGG CGACATCGGC AAGGGTCTTC AAGCACTCGG ATACAACGAC


 


751
GAAACGTCCA GACACGCGCT CCTGCGCTAC CGCGAAACCG TCGAACAGTC


 


801
GCCCCTCTAC CAAAAAATAC AGACAGGATG CATCGACTGG CAGAGCGTCC


 


851
GAACCCGCCT CATCAGCGAC GACCCTGCAA AAGGACTCGA CCGCGACCGC


 


901
CGCAAACCGC CGATTGCCGG GCGGCTGCAA GACGCGCTCA AACAGCCCGA


 


951
AAAAAGCGTC TATCTGGTTT CACCCTATTT CGTTCCCACA AAATCCGGCA


 


1001
CAGACGCACT GGCAAAACTG GTGCAGGACG GCATAGACGT TACCGTTCTG


 


1051
ACCAACTCGC TGCAGGCGAC CGACGTTGCC GCCGTCCATT CCGGCTATGT


 


1101
CAAATACCGA AAACCGCTGC TCAAAGCCGG CATCAAACTC TACGAGCTGC


 


1151
AACCCAACCA TGCCGTCCCC GCCACAAAAG ACAAAGGCCT GACCGGCAGC


 


1201
TCCGTAACCA GCCTGCACGC CAAAACCTTC ATTGTGGACG GCAAACGCAT


 


1251
CTTCATCGGT TCGTTCAACC TCGACCCCCG TTCCGCGCGT CTCAACACCG


 


1301
AAATGGGCGT TGTTATCGAA AGCCCCAAAA TCGCAGAACA GATGGAGCGC


 


1351
ACCCTTGCCG ATACCACACC CGCCTACGCC TACCGCGTTA CCCTCGACAG


 


1401
GCACAACCGC CTGCAATGGC ACGATCCCGC CACCCGAAAA ACCTACCCGA


 


1451
ACGAACCCGA AGCCAAACTT TGGAAACGCA TCGCCGCAAA AATCCTATCC


 


1501
CTGCTGCCCA TAGAAGGTTT ATTATAG






This corresponds to the amino acid sequence <SEQ ID 2976; ORF 987>:










m987.pep




1
MKTRSLISLL CLLLCSCSSW LPPLEERTES RHFNTSKPVR LDNILQIRHT


 


51
PHTNGLSDIY LLNDPHEAFA ARAALIESAE HSLDLQYYIW RNDISGRLLF


 


101
NLVYLAAERG VRVRLLLDDN NTRGLDDLLL ALDSHPNIEV RLFNPFVLRK


 


151
WRALGYLTDF PRLNRRMHNK SFTADNRATI LGGRNIGDEY FKVGEDTVFA


 


201
DLDILATGSV VGEVSHDFDR YWASHSAHNA TRIIRSGDIG KGLQALGYND


 


251
ETSRHALLRY RETVEQSPLY QKIQTGCIDW QSVRTRLISD DPAKGLDRDR


 


301
RKPPIAGRLQ DALKQPEKSV YLVSPYFVPT KSGTDALAKL VQDGIDVTVL


 


351
TNSLQATDVA AVHSGYVKYR KPLLKAGIKL YELQPNHAVP ATKDKGLTGS


 


401
SVTSLHAKTF IVDGKRIFIG SFNLDPRSAR LNTEMGVVIE SPKIAEQMER


 


451
TLADTTPAYA YRVTLDRHNR LQWHDPATRK TYPNEPEAKL WKRIAAKILS


 


501
LLPIEGLL*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m987/g987 97.8% identity in 508 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2977>:










a987.seq




1
ATGAAAACAC GCAGCCTAAT TTCCCTTTTA TGCCTCCTTC TCTGTTCATG


 


51
TTCTTCATGG TTGCCCCCAC TGGAAGAACG GACGGAAAGC CGTCATTTCA


 


101
ATACTTCCAA ACCCGTCCGC CTGGACAACA TCCTGCAAAT CCGGCACACC


 


151
CCTCATACCA ACGGGCTATC CGATATCTAT CTGTTGAACG ACCCCCACGA


 


201
AGCCTTTGCC GCCCGCGCCG CCCTTATCGA ATCTGCCGAA CACAGCCTCG


 


251
ATTTGCAATA CTACATCTGG CGCAACGACA TTTCCGGCCG ACTGCTGTTC


 


301
AACCTCGTGT ACCTTGCCGC AGAACGCGGT GTGCGCGTAC GCCTGCTGTT


 


351
GGACGACAAC AACACGCGCG GATTGGACGA CCTCCTGCTC GACCTGGACA


 


401
GCCATCCCAA TATCGAAGTG CGCCTGTTCA ACCCCTTCGT CTTACGAAAA


 


451
TGGCGCGCAC TCGGCTACCT GACCGACTTC CCCCGCCTCA ACCGCCGCAT


 


501
GCACAACAAA TCCTTTACCG CCGACAACCG CGCCACCATA CTCGGCGGAC


 


551
GCAATATCGG CGACGAATAC TTCAAAGTCG GTGAGGACAC CGTTTTCGCC


 


601
GACCTGGACA TCCTCGCCAC CGGCAGCGTC GTCGGCGAAG TATCGCACGA


 


651
CTTCGACCGC TACTGGGCAA GCCATTCCGC CCACAACGCC ACGCGCATCA


 


701
TCCGCAGCGG CAACATCGGC AAGGGTCTTC AAGCACTCGG ATACAACGAC


 


751
GAAACGTCCA GACACGCGCT CCTGCGCTAC CGCGAAACCG TCGAACAGTC


 


801
GCCCCTCTAC CAAAAAATAC AGACAGGACG CATCGACTGG CAGAGCGTCC


 


851
AAACCCGCCT CATCAGCGAC GACCCTGCAA AAGGACTCGA CCGCGACCGC


 


901
CGCAAACCGC CGATTGCCGG GCGGCTGCAA GACGCGCTCA AACAGCCCGA


 


951
AAAAAGCGTC TATCTGGTTT CACCCTATTT CGTCCCCACA AAATCCGGCA


 


1001
CAGACGCACT GGCAAAACTG GTGCAGGACG GCATAGACGT TACCGTCCTG


 


1051
ACCAACTCGC TACAGGCGAC CGACGTTGCC GCCGTCCATT CCGGCTATGT


 


1101
CAAATACCGA AAACCGCTGC TCAAAGCCGG CATCAAACTC TACGAGCTGC


 


1151
AACCCAACCA TGCCGTCCCT GCCACAAAAG ACAAAGGCCT GACCGGCAGC


 


1201
TCCGTAACCA GCCTGCATGC CAAAACCTTC ATTGTGGACG GCAAACGCAT


 


1251
CTTCATCGGC TCATTCAACC TCGACCCCCG TTCCGCACGG CTCAATACTG


 


1301
AAATGGGCGT TGTTATCGAA AGCCCCAAAA TCGCAGAACA GATGGAGCGC


 


1351
ACCCTTGCCG ATACCTCACC CGAATACGCC TACCGCGTTA CCCTCGACAG


 


1401
GCACAACCGC CTGCAATGGC ACGATCCCGC CACCCGAAAA ACCTACCCGA


 


1451
ACGAACCCGA AGCCAAACTT TGGAAACGCA TCGCCGCAAA AATCCTATCC


 


1501
CTGCTGCCCA TAGAAAGTTT ATTATAG






This corresponds to the amino acid sequence <SEQ ID 550; ORF 2978.a>:










a987.pep




1
MKTRSLISLL CLLLCSCSSW LPPLEERTES RHFNTSKPVR LDNILQIRHT


 


51
PHTNGLSDIY LLNDPHEAFA ARAALIESAE HSLDLQYYIW RNDISGRLLF


 


101
NLVYLAAERG VRVRLLLDDN NTRGLDDLLL ALDSHPNIEV RLFNPFVLRK


 


151
WRALGYLTDF PRLNRRMHNK SFTADNRATI LGGRNIGDEY FKVGEDTVFA


 


201
DLDILATGSV VGEVSHDFDR YWASHSAHNA TRIIRSGNIG KGLQALGYND


 


251
ETSRHALLRY RETVEQSPLY QKIQTGRIDW QSVQTRLISD DPAKGLDRDR


 


301
RKPPIAGRLQ DALKQPEKSV YLVSPYFVPT KSGTDALAKL VQDGIDVTVL


 


351
TNSLQATDVA AVHSGYVKYR KPLLKAGIKL YELQPNHAVP ATKDKGLTGS


 


401
SVTSLHAKTF IVDGKRIFIG SFNLDPRSAR LNTEMGVVIE SPKIAEQMER


 


451
TLADTSPEYA YRVTLDRHNR LQWHDPATRK TYPNEPEAKL WKRIAAKILS


 


501
LLPIESLL*






m987/a987 98.8% identity in 508 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2979>:










g988.seq




1
ATGAATAAAA ATATTAAATC TTTAAATTTA CGGGAAAAAG ACCCGTTTTT


 


51
AAGTCGTGAA AAACAGCGTT ATGAACATCC TTTGCCCAGT CGGgaATGGA


 


101
TAATCGAATT GTTGGAGCGC AAAGGTGTGC CTTCAAAAAT CGAATCGCTT


 


151
GCACGCGAGC TGTCGATTAC GGAAGacgag tATGTCTTTT TTGAACGCCG


 


201
TCTGAaggCG atgGCGCGGG AcggtCAGGT TTTAATCAAC CGCCgaggcg


 


251
CagtTTGCGc gGCggacaag ctgGATTTGG TCAAATGccg Cgtcgaggcg


 


301
catAAgGAcg gtttcggctt cgcCGTGCCG CTCATGCCGA TGGACGAAGG


 


351
GGATTTCGTT TTATACGAAC GCCAgatgcg tggTGtcatG CAcggcgaca


 


401
ccgttACCGT CCGTCCTGCg ggtatggaCC GCAGGGGccg ccgcGAAggg


 


451
acgtttctGG ATATTGTCGA ACGCGCGCAA AGCAAAGTTG TCGGCCGTTT


 


501
CTATATGGAT AGGGGCGTGG CGATTTTGGA GCCGGAAGAC AAGCGTCTGA


 


551
ACCAAAGCAT CGTGTTGGAA CCGGACGGCG TGGCGCGTTT CAAACCCGAA


 


601
TCCGGTCAGG TTATCGTCGG CAAAATTGAG GTTTATCCCG AGCAAAACCG


 


651
GCCTGCAGTG GCAAAAATCA TTGAAGTTTT GGGCGATTAT GCCGACAGCG


 


701
GGATGGAAAt cgAAATTGCC GTGCGCAAGC ATCATTTGCC GCAccgaTTC


 


751
AGTGAagcgt gtGcCAAATC CGcgaaAAAA ATtcccgacc ATGTACGCAA


 


801
AAGCGATTTG AAAGGCCGCG TCGATTTGTG CGACCTTCCT TTGGTAACGA


 


851
TAGACGGCGA AACGGCGCGC GATTTCGACG ACGCGGTGTT TGCCGAAAAA


 


901
GTCGGACGCA ATTACCGCCT GGTCGTGGCG ATTGCGGATG TCAGCCATTA


 


951
TGTCCGCCCT GACGATGCGA TTGATGCAGA TGCTCAAGAA CGCAGTACCA


 


1001
GCGTGTATTT CCCGCGCCGT ATGATTCCGA TGCTGCCGGA AAACCTGTCC


 


1051
AACGGCATCT GCTCGCTCAA TCCCGATGTC GAGCGTTTGT GTATGGTGTG


 


1101
CGATATGGTC GTTACCTATG CGGGCAATAT CAAAGAATAC CGCTTCTATC


 


1151
CCGCCGTGAT GCGCTCTCAT GCCCGCCTGA CCTACAACCA AGTTTGGAAA


 


1201
TGGCTTTCAG ACGGCATCGG GAATCCGCAC AAAGCCCAAA TCGACACGCT


 


1251
TTACAAGCTG TTTAAAATTT TGCAGAAAAA ACGTCTGGCG CGCGGGGCGG


 


1301
TGGAGTTTGA AAGCGTCGAA ACCCAGATGA TTTTCGACGA CAACGGCAAA


 


1351
ATCGAAAAAA TTGTCCCCGT CGTCCGCAAC gatGCCCACA AGCTGATTGA


 


1401
AGAATGTATG CTGGCGGCGA ATGTTTGCGC GGCGGATTTT CTGTTGAAAA


 


1451
ACAAACATAC GGCTTTGTTC CGCAACCATT TGGGCCCCAC GCCCGAAAAA


 


1501
CTCGCCACCC TGCGCGAGCA GCTCGGTCTG TTGGGGCTTC AACTTGGCGG


 


1551
CGGCGACAAC CCGTCGCCGA AAGACTATGC CGCGCTTGCC GAACAATTCA


 


1601
AAGGCAGGCC GGATGCCGAA TTGCTGCAAG TCATGATGTT GCGCTCCATG


 


1651
CAGCAGGCGG TTTACGAACC GCATTGCGAA GGGCATTTCG GTTTGGCTTA


 


1701
TGAAGCATAC GCCCACTTTA CCTCGCCCAT CCGCCGCTAT CCCGACCTGA


 


1751
CCGTCCACCG TGCCATCAAA GCCGTATTGA ACCGGAAAAC CTACACGCCA


 


1801
AACAAAAGCT GGCAGGCTTT GGGCGTGCAT ACTTCGTTTT GCGAACGCCG


 


1851
TGCCGACGAT GCTGGCCGCG ATGTGGAAAA CTGGCTGAAA ACTTATTATA


 


1901
TGCGCGATAA GGTCGGTGAA ATATTTGAAG GcaaaatCtc ccggggtgtg


 


1951
gcaaaTtttg gaATATTTGT CACTTTGGAC GATATccata tcgacggtct


 


2001
ggtacaTATC AGCGatttgg gcgaAGATTA TTTCaacttc cgccccgAAA


 


2051
TCATGGCAAT CGAAGGCGAA CGCAGCGGCA TCCGTTTCAA TATGGGGGAC


 


2101
AGGGTTGCCG TCCGGGTCGC GCGTGCCGAT TTGGATGATG GAAAAATCGA


 


2151
CTTTGTCCTA ATTGCCGGAG AAAGCGGCAG GCGGCGGAAG GTCAAATTAT


 


2201
CCGCATCTGC CAAACCGGCA GGGGCGGCGG GGAAAGGGAA ATCGAAAACC


 


2251
ACCGCCGAGA AAAAAACAGC CCGATGCGGC AAAGTAAGGG GAAGGGGCGT


 


2301
GCCTGCCGTT GCCGAATCGG GGAAAAAGGC AAAGAAACCG GTTCCGATTA


 


2351
AGGTCAAAAA ACGGAAAGGC AAATCATAA






This corresponds to the amino acid sequence <SEQ ID 2980; ORF 988.ng>:










g988.pep




1
MNKNIKSLNL REKDPFLSRE KQRYEHPLPS REWIIELLER KGVPSKIESL


 


51
ARELSITEDE YVFFERRLKA MARDGQVLIN RRGAVCAADK LDLVKCRVEA


 


101
HKDGFGFAVP LMPMDEGDFV LYERQMRGVM HGDTVTVRPA GMDRRGRREG


 


151
TFLDIVERAQ SKVVGRFYMD RGVAILEPED KRLNQSIVLE PDGVARFKPE


 


201
SGQVIVGKIE VYPEQNRPAV AKIIEVLGDY ADSGMEIEIA VRKHHLPHRF


 


251
SEACAKSAKK IPDHVRKSDL KGRVDLCDLP LVTIDGETAR DFDDAVFAEK


 


301
VGRNYRLVVA IADVSHYVRP DDAIDADAQE RSTSVYFPRR MIPMLPENLS


 


351
NGICSLNPDV ERLCMVCDMV VTYAGNIKEY RFYPAVMRSH ARLTYNQVWK


 


401
WLSDGIGNPH KAQIDTLYKL FKILQKKRLA RGAVEFESVE TQMIFDDNGK


 


451
IEKIVPVVRN DAHKLIEECM LAANVCAADF LLKNKHTALF RNHLGPTPEK


 


501
LATLREQLGL LGLQLGGGDN PSPKDYAALA EQFKGRPDAE LLQVMMLRSM


 


551
QQAVYEPHCE GHFGLAYEAY AHFTSPIRRY PDLTVHRAIK AVLNRKTYTP


 


601
NKSWQALGVH TSFCERRADD AGRDVENWLK TYYMRDKVGE IFEGKISRGV


 


651
ANFGIFVTLD DIHIDGLVHI SDLGEDYFNF RPEIMAIEGE RSGIRFNMGD


 


701
RVAVRVARAD LDDGKIDFVL IAGESGRRRK VKLSASAKPA GAAGKGKSKT


 


751
TAEKKTARCG KVRGRGVPAV AESGKKAKKP VPIKVKKRKG KS*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2981>:









m988.seq (partial)










1
..ACAGTTCTGG ATATTGTCGA ACGCGCGCAA AGCAAAGTGG TCGGCCGTTT



 


51
  CTATATGGAT AGGGGCGTGG CGATTTTGGA GCCGGAAGAC AAGCGTCTGA


 


101
  ACCAAAGCAT CGTATTGGAA CCGGACGGCG TGGCGCGTTT CAAACCTGAA


 


151
  TCCGGTCAGG TCATCGTCGG CGAAATTGAG GTTTATCCTG AGCAAAACCG


 


201
  GCCGGCAGTG GCAAAAATCA TCGAAGTTTT GGGCGATTAT GCCGACAGCG


 


251
  GCATGGAGAT TGAAATTGCC GTGCGCAAGC ATCATTTGCC GCACCAATTC


 


301
  AGTGAAGCGT GTGCCAAAGC TGCGAAAAAA ATTCCCGTCC ATGTACGCAA


 


351
  AAGCGATTTG AAAGGCCGCG TCGATTTGCG CGACCTGCCT TTGGTAACGA


 


401
  TAGACGGCGA AACGGCGCGC GATTTCGACG ACGCGGTGTT TGCCGAAAAA


 


451
  GTCGGACGCA ATTACCGTCT GGTCGTGGCG ATTGCGGATG TCAGCCATTA


 


501
  TGTCCGCCCT GACGATGTGA TTGATGCAGA TGCTCAAGAA CGCAGTACCA


 


551
  GCGTATATTT CCCGCGCCGT GTGATTCCGA TGCTGCCGGA AAACCTGTCT


 


601
  AACGGCATTT GCTCGCTCAA TCCCGATGTC GAGCGTTTGT GTATGGTGTG


 


651
  CGATATGGTC GTTACCTATG CGGGCAATAT CAAAGAATAC CGCTTCTACC


 


701
  CCGCCGTAAT GCGCTCTCAT GCCCGCCTGA CCTACAACCA AGTTTGGAAA


 


751
  TGGATTTCAG ACGGCATCGA CCATCCGTAC AAAGCCCAAA TCGACACCCT


 


801
  TTACAAACTC TTCAAAATCC TTCAGAAAAA GCGTTTCGAA CGCGGCGCGG


 


851
  TGGAGTTTGA AAGCGTCGAA ACCCAGATGA TTTTCGATGA CAACGGCAAA


 


901
  ATCGAAAAAA TCGTCCCCGT TGTCCGCAAC GATGCCCACA AGCTGATTGA


 


951
  AGAATGTATG CTGGCGGCGA ATGTTTGCGC AGCGGATTTC CTGTTGAAAA


 


1001
  ACAAGCATAC GGCTTTGTTC CGCAACCATT TGGGCCCCAC GCCCGAAAAA


 


1051
  CTCGCCACCC TGCGCGAGCA GCTCGGTCTG TTGGGGCTTC AACTTGGCGG


 


1101
  CGGCGACAAC CCGTCGCCGA AAGACTATGC CGCGCTTGTC GAACAATTCA


 


1151
  AAGGCAGACC TGATGCCGAA TTGCTGCAAG TCATGATGTT GCGCTCCATG


 


1201
  CAGCAGGCGG TTTACGAACC GCATTGCGAC GGACACTTTG GTCTTGCCTA


 


1251
  CGAAGCATAC GCCCACTTCA CCTCGCCCAT CCGCCGCTAT CCCGACCTGA


 


1301
  CCGTACACCG CGCCATCAAA GCCGTGTTGA ATCAGCAAAC CTACACGCCA


 


1351
  AAAAAAAGCT GGCAGGCTTT GGGCGTGCAT ACCTCGTTCT GTGAGCGCCG


 


1401
  TGCCGACGAC GCCAGCCGCG ACGTGGAAAA CTGGCTGAAA ACCTATTATA


 


1451
  TGCGCGATAA GGTCGGCGAA GTATTCGAAG GTAAAATCTC CGGCATGACC


 


1501
  AGTTTTGGTA TCTTTGTAAC ACTGGACGGC ATCCACATTG ACGGCTTGGT


 


1551
  GCATATCAGC GATTTGGGCG AAGACTATTT CAACTTCCGC CCCGAAATCA


 


1601
  TGGCAATCGA AGGCGAACGC AGCGGCATCC GTTTCAACAT GGGGGACAGG


 


1651
  GTTGCCGTCC GGGTCGCCCG TGCCGATTTG GATGACGGAA AAATCGATTT


 


1701
  TGTCCTGATT GCCGGGGGGA GCGGCAGGGG GCGGAAAGTT AAATCATCCG


 


1751
  CGTCTGCCAA ACCGGCAGGG ACGGCGGGGA AAGGGAAGCC GAAAACCGCC


 


1801
  GCCGAGAAAA AAACAGCCCG AGGCGGCAAA GTAAGGGGAA GGGGCGCGTC


 


1851
  TGCCGCCGCA GAATCGAGGA AAAAGGCAAA GAAACCGGTT CCGATTAAGG


 


1901
  TAAAAAAACG GAAAGGCAAA TCATAA






This corresponds to the amino acid sequence <SEQ ID 2982; ORF 988>:









m988.pep (partial)










1
..TVLDIVERAQ SKVVGRFYMD RGVAILEPED KRLNQSIVLE PDGVARFKPE



 


51
  SGQVIVGEIE VYPEQNRPAV AKIIEVLGDY ADSGMEIEIA VRKHHLPHQF


 


101
  SEACAKAAKK IPVHVRKSDL KGRVDLRDLP LVTIDGETAR DFDDAVFAEK


 


151
  VGRNYRLVVA IADVSHYVRP DDVIDADAQE RSTSVYFPRR VIPMLPENLS


 


201
  NGICSLNPDV ERLCMVCDMV VTYAGNIKEY RFYPAVMRSH ARLTYNQVWK


 


251
  WISDGIDHPY KAQIDTLYKL FKILQKKRFE RGAVEFESVE TQMIFDDNGK


 


301
  IEKIVPVVRN DAHKLIEECM LAANVCAADF LLKNKHTALF RNHLGPTPEK


 


351
  LATLREQLGL LGLQLGGGDN PSPKDYAALV EQFKGRPDAE LLQVMMLRSM


 


401
  QQAVYEPHCD GHFGLAYEAY AHFTSPIRRY PDLTVHRAIK AVLNQQTYTP


 


451
  KKSWQALGVH TSFCERRADD ASRDVENWLK TYYMRDKVGE VFEGKISGMT


 


501
  SFGIFVTLDG IHIDGLVHIS DLGEDYFNFR PEIMAIEGER SGIRFNMGDR


 


551
  VAVRVARADL DDGKIDFVLI AGGSGRGRKV KSSASAKPAG TAGKGKPKTA


 


601
  AEKKTARGGK VRGRGASAAA ESRKKAKKPV PIKVKKRKGK S*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

m988/g988 94.2% identity in 642 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2983>:










a988.seq




1
ATGAATAAAA ATATTAAATC TTTAAATTTA CGGGAAAAAG ACCCGTTTTT


 


51
AAGTCGTGAA AAACAGCGTT ATGAACATCC TTTGCCCAGT CGGGAATGGA


 


101
TAATCGAGCT GCTTGAACGT AAAGGCGTAC CATCCAAGAT TGAAGCTTTG


 


151
GTACGCGAAT TGTCGATTAA GGAAGAAGAG TACGAATTTT TCGAACGTCG


 


201
TCTGAAGGCG ATGGCGCGGG ACGGTCAGGT TTTAATCAAC CGTCGGGGCG


 


251
CGGTTTGCGC GGCGGACAAA TTGGATTTGG TCAAATGCCG TGTCAAGGCG


 


301
CACAAAGACC GCTTCGGTTT CGCCGTGCCG CTCACGCCCG CCAAAGACGG


 


351
TGATTTTGTC TTGTACGAAC GCCAGATGCG CGGCATTATG CACGGCGATA


 


401
TTGTCACTGT TCGTCCTGCC GGCATGGACG GTAGGGGCCG CCGCGAAGGG


 


451
ACGGTTCTGG ATATTGTCGA ACGCGCGCAA AGCAAAGTGG TCGGCCGTTT


 


501
CTANATGGAT AGGGGCGTGG CGATTTTGGA GCCGGAAGAC AAGCGTCTGA


 


551
ACCAAAGCAT CGTATTGGAA CCGGACGGCG TGGCGCGTTT CAAACCTGAA


 


601
TCCGGTCAGG TCATCGTCGG CGAAATTGAG GTTTATCCTG AGCAAAACCG


 


651
GCCGGCAGTG GCAAAAATCA TCGAAGTTTT GGGCGATTAT GCCGACAGCG


 


701
GCATGGAGAT TGAAATTGCC GTGCGCAAGC ATCATTTGCC GCACCAATTC


 


751
AGTGAAGCGT GTGCCAAAGC CGCGAAAAAA ATTCCCGACC ATGTACGCAA


 


801
AAGCGATTTG AAAGGCCGCG TCGATTTGCG CGACCTGCCT TTGGTAACGA


 


851
TAGACGGCGA AACGGCTCGA GATTTTGACG ATGCGGTGTT TGCCGAGAAA


 


901
ATCGGACGCA ATTACCGTCT GGTCGTGGCG ATTGCCGATG TCAGCCATTA


 


951
TGTCCGCCCC GATGACGCTA TCGACACGGA CGCTCAGGAA CGCAGCACCA


 


1001
GTGTTTACTT CCCGCGCCGC GTGATTCCCA TGTTGCCGGA AAACCTGTCC


 


1051
AACGGCATCT GCTCGCTCAA TCCTCATGTC GAGCGTTTGT GTGTGGTGTG


 


1101
CGATATGGTT ATCACTTACG CGGGCAATAT CAAAGAATAC CGCTTCTACC


 


1151
CCGCCGTGAT GCGCTCTCAT GCCCGCCTGA CCTACAACCA AGTTTGGAAA


 


1201
TGGCTTTCAG GCGGCATCGA GCATCCGTTC AAAACCCAAA TCGACACGCT


 


1251
TTACAAACTC TTCAAAATCC TTCAGAAAAA GCGTTTCGAA CGCGGGGCGG


 


1301
TGGAGTTTGA CAGCATCGAA ACCCAAATGC TTTTCGACGA CAACGGTAAA


 


1351
ATTGAAAAAA TCGTCCCCGT TGTCCGCAAC GATGCCCACA AGCTGATTGA


 


1401
AGAATGTATG TTGGCGGCAA ACGTTTGCGC AGCGGATTTT CTGTTGAAAA


 


1451
ACAAGCATAC CGCATTGTTC CGCAACCATT TGGGGCCCAC GCCCGAAAAA


 


1501
CTCGCCGCCT TGCGCGAGCA GCTCGGTCTG TTGGGGCTTC AACTTGGCGG


 


1551
CGGCGACAAC CCGTCGCCGA AAGACTATGC CGCGCTTGCC GGACAGTTCA


 


1601
AAGGCAGGCC GGATGCCGAA TTGCTGCAAG TCATGATGTT GCGCTCCATG


 


1651
CAACAGGCGG TTTACGAACC GCATTGCGAC GGACACTTTG GTCTTGCCTA


 


1701
CGAAGCATAC GCCCACTTCA CCTCGCCCAT CCGCCGCTAT CCCGACCTGA


 


1751
CCGTACACCG CGCCATCAAA GCCGTGTTGA ATCAGCAAAC CTACACGCCA


 


1801
AAAAAAAGCT GGCAGGCTTT GGGCGTGCAT ACCTCGTTCT GTGAGCGCCG


 


1851
TGCCGACGAC GCCAGCCGCG ACGTGGAAAA CTGGCTGAAA ACCTATTATA


 


1901
TGCGCGATAA GGTCGGCGAA GTATTCGAAG GTAAAATCTC CGGCATGACC


 


1951
AGTTTTGGTA TCTTTGTAAC ACTGGACGGC ATCCACATTG ACGGCTTGGT


 


2001
GCATATCAGC GATTTGGGCG AAGACTATTT CAACTTCCGC CCCGAAATCA


 


2051
TGGCAATCGA AGGCGAACGC AGCGGCATCC GTTTCAACAT GGGGGACAGG


 


2101
GTTGCCGTCC GGGTCGCCCG TGCCGATTTG GATGACGGAA AAATCGATTT


 


2151
TGTCCTGATT GCCGGGGGGA GCGGCAGGGG GCGGAAAGTT AAATCATCCG


 


2201
CGTCTGCCAA ACCGGCAGGG ACGGCGGGGA AAGGGAAGCC GAAAACCGCC


 


2251
GCCGAGAAAA AAACAGCCCG AGGCGGCAAA GTAAGGGGAA GGGGCGCGTC


 


2301
TGCCGCCGCA GAATCGAGGA AAAAGGCAAA GAAACCGGTT CCGATTAAGG


 


2351
TAAAAAAACG GAAAGGCAAA TCATAA






This corresponds to the amino acid sequence <SEQ ID 2984; ORF 988.a>:










a988.pep




1
MNKNIKSLNL REKDPFLSRE KQRYEHPLPS REWIIELLER KGVPSKIEAL


 


51
VRELSIKEEE YEFFERRLKA MARDGQVLIN RRGAVCAADK LDLVKCRVKA


 


101
HKDRFGFAVP LTPAKDGDFV LYERQMRGIM HGDIVTVRPA GMDGRGRREG


 


151
TVLDIVERAQ SKVVGRFXMD RGVAILEPED KRLNQSIVLE PDGVARFKPE


 


201
SGQVIVGEIE VYPEQNRPAV AKIIEVLGDY ADSGMEIEIA VRKHHLPHQF


 


251
SEACAKAAKK IPDHVRKSDL KGRVDLRDLP LVTIDGETAR DFDDAVFAEK


 


301
IGRNYRLVVA IADVSHYVRP DDAIDTDAQE RSTSVYFPRR VIPMLPENLS


 


351
NGICSLNPHV ERLCVVCDMV ITYAGNIKEY RFYPAVMRSH ARLTYNQVWK


 


401
WLSGGIEHPF KTQIDTLYKL FKILQKKRFE RGAVEFDSIE TQMLFDDNGK


 


451
IEKIVPVVRN DAHKLIEECM LAANVCAADF LLKNKHTALF RNHLGPTPEK


 


501
LAALREQLGL LGLQLGGGDN PSPKDYAALA GQFKGRPDAE LLQVMMLRSM


 


551
QQAVYEPHCD GHFGLAYEAY AHFTSPIRRY PDLTVHRAIK AVLNQQTYTP


 


601
KKSWQALGVH TSFCERRADD ASRDVENWLK TYYMRDKVGE VFEGKISGMT


 


651
SFGIFVTLDG IHIDGLVHIS DLGEDYFNFR PEIMAIEGER SGIRFNMGDR


 


701
VAVRVARADL DDGKIDFVLI AGGSGRGRKV KSSASAKPAG TAGKGKPKTA


 


751
AEKKTARGGK VRGRGASAAA ESRKKAKKPV PIKVKKRKGK S*






m988/a988 97.0% identity in 641 aa overlap




The following partial DNA sentience was identified in N. gonorrhoea <SEQ ID 2985>:










g989.seq




1
ATGACCCCTT TCACACTGAA AAAAACCGTC CTGCTGCTCG GCACTGCCTT


 


51
TGCCGCCGCA TCTGTCCACG CATCCGGCTA CCACTTCGGC ACACAGTCGG


 


101
TCAACGCGCA AAGCACGGCA AATGCCGCCG ACGCGTCGAC CATCTTCTAC


 


151
AATCCCGCCG GCCTGACCAA ACTCGACAGC AGCCAGATTT CCGTCAACGC


 


201
CAACATCGTG CTGCCCAGCA TTCATTATGA AGCAGATTCC GCCACCGACT


 


251
TTACCGGGCT TCCCGTCCAA GGTTCTAAAA ACGGCAAAAT CACCAAAACC


 


301
ACGGTCGCAC CCCACATTTA CGGCGCATAC AAAGTCAACG ACAATCTGAC


 


351
CGTGGGCTTG GGCGTGTACG TCCCCTTCGG CTCTGCCACC GAATACGAAA


 


401
AAGATTCCGT GTTGCGCCAC AACATCAACA AACTCGGTCT GACCAGCATC


 


451
GCCGTCGAAC CTGTCGCCGC GTGGAAACTC AACGAACGCC ATTCCTTCGG


 


501
CGCAGGCATC ATCGCCCAAC ATAATTCCGC CGAACTGCGC AAATATGCCG


 


551
ACTGAGGAAT CCCAAAAAAA GCGCAAATGC TGCAAGCAAC ACCTTCTAAT


 


601
CCTACTGCCG CTGCTCAAAT CAAGGCCGAC GGACACGCCG ATGTCAAAGG


 


651
CAGCGATTGG GGCGTCGGCT ACCAACTGGC GTGGATGTGG GACATCAACG


 


701
ACCGCGCGCG CGTGGGCGTG AACTACCGTT CCAAAGTTTC ACACACGCTC


 


751
AAAGGCGATG CCGAATGGGC GGCAGACGGC GCGGCGGCGA AACAACAGTG


 


801
GAATGACAAT ATGCTCACAC CGCTCGGTTA CACGGCGAAT GAAAAAGCCA


 


851
GTGTCAAAAT CGTAACGCCT GAGTCTTTGT CCGTACACGG CATGTACAAA


 


901
GTGTCCGACA AAGCCGACCT GTTCGGCGAC GTAACTTGGA CGCGCCACAG


 


951
CCGCTTCAAT AAGGCGGAAC TGTTTTTTGA AAAAGAAAAA AATATTGCTA


 


1001
ATGGCAAAAA ATCCGACCGC ACCACCATCA CCCCCAACTG GCGCAACACC


 


1051
TACAAAGTCG GCTTGGGCGG TTCTTATCAA ATCAGCGAAC CGCTGCAACT


 


1101
GCGCGTCGGC ATCGCTTTTG ACAAACCGCC TGTCCGCAAC GCCGACTacC


 


1151
GCATGAACAG CCTGCCCGAC GGCAACCGCA TCTGGTTCTC CGCCGGCATG


 


1201
AAATACCATA TCGGCAAAAA CCACGTCGTC GATGCCGCCT ACACCCACAT


 


1251
CCACATCAAC GACACCAGCT ACCGCACGGC GAAGGCAAGC GGCAACGATG


 


1301
TGGACAGCAA AGGTGCGTCT TGCGCACGTT TCAAAAACCA CGCCGACATC


 


1351
ATCGGCCTGC AATACACCTA CAAATTCAAA TAA






This corresponds to the amino acid sequence <SEQ ID 2986; ORF 989.ng>:










g989.pep




1
MTPFTLKKTV LLLGTAFAAA SVHASGYHFG TQSVNAQSTA NAADASTIFY


 


51
NPAGLTKLDS SQISVNANIV LPSIHYEADS ATDFTGLPVQ GSKNGKITKT


 


101
TVAPHIYGAY KVNDNLTVGL GVYVPFGSAT EYEKDSVLRH NINKLGLTSI


 


151
AVEPVAAWKL NERHSFGAGI IAQHNSAELR KYAD*GIPKK AQMLQATPSN


 


201
PTAAAQIKAD GHADVKGSDW GVGYQLAWMW DINDRARVGV NYRSKVSHTL


 


251
KGDAEWAADG AAAKQQWNDN MLTPLGYTAN EKASVKIVTP ESLSVHGMYK


 


301
VSDKADLFGD VTWTRHSRFN KAELFFEKEK NIANGKKSDR TTITPNWRNT


 


351
YKVGLGGSYQ ISEPLQLRVG IAFDKPPVRN ADYRMNSLPD GNRIWFSAGM


 


401
KYHIGKNHVV DAAYTHIHIN DTSYRTAKAS GNDVDSKGAS CARFKNHADI


 


451
IGLQYTYKFK *






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2987>:










m989.seq




1
ATGACCCCTT CCGCACTGAA AAAAACCGTC CTGCTGCTCG GCACTGCCTT


 


51
TGCCGCCGCA TCCGTCCACG CATCCGGCTA CCACTTCGGC ACACAGTCGG


 


101
TCAACGCGCA AAGCACGGCA AATGCCGCCG CCGCAGAAGC CGCCGACGCA


 


151
TCGACCATCT TCTACAACCC TGCCGGCCTG ACCAAACTCG ACAGCAGCCA


 


201
GATTTCCGTC AACGCCAACA TCGTGCTGCC CAGCATTCAT TATGAGGCGG


 


251
ATTCCGCCAC CGACTTTACC GGGCTTCCCG TCCAAGGTTC GAAAAGCGGC


 


301
AAAATCACCA AAACCACGGT CGCGCCCCAC ATCTACGGCG CATACAAAGT


 


351
CAACGACAAT CTGACCGTGG GCTTGGGCGT GTACGTCCCC TTCGGCTCTG


 


401
CCACCGAATA CGAAAAAGAT TCCGTGTTGC GCCACAACAT CAACAAACTC


 


451
GGTCTGACCA GCATCGCCGT CGAACCTGTC GCCGCGTGGA AACTCAACGA


 


501
CCGCCATTCC TTCGGCGCAG GCATCATCGC CCAACATACT TCCGCCGAAC


 


551
TGCGCAAATA TGCCGACTGG GGGATTAAGA GTAAAGCAGA GATATTGACG


 


601
GCAAAACCGC CCAAACCTAA CGGTGTAGCC GAAGCTGCAA AAATTCAGGC


 


651
CGACGGACAC GCCGATGTCA AAGGCAGCGA TTGGGGCTTC GGCTACCAAC


 


701
TGGCGTGGAT GTGGGACATC AACGACCGTG CGCGCGTGGG CGTGAACTAC


 


751
CGTTCCAAAG TCTCGCACAC GCTCAAAGGC GATGCCGAAT GGGCGGCAGA


 


801
CGGCGCGGCG GCGAAAGCAA TGTGGAGTAC GATGCTTGCA GCAAACGGCT


 


851
ACACGGCGAA TGAAAAAGCC CGCGTTAAAA TCGTTACGCC TGAGTCTTTG


 


901
TCCGTACACG GTATGTACAA AGTGTCCGAT AAAGCCGACC TGTTCGGCGA


 


951
CGTAACTTGG ACGCGCCACA GCCGCTTCGA TAAGGCGGAA CTGGTTTTTG


 


1001
AAAAAGAAAA AACCGTCGTC AAAGGCAAAT CCGACCGCAC CACCATCACC


 


1051
CCCAACTGGC GCAACACCTA CAAAGTCGGC TTCGGCGGTT CTTATCAAAT


 


1101
CAGCGAACCG CTGCAACTGC GCGCCGGCAT CGCTTTTGAC AAATCGCCCG


 


1151
TCCGCAACGC CGACTACCGC ATGAACAGCC TACCCGACGG CAACCGCATC


 


1201
TGGTTCTCCG CCGGTATGAA ATACCATATC GGTAAAAACC ACGTCGTCGA


 


1251
TGCCGCCTAC ACCCACATCC ACATCAACGA CACCAGCTAC CGCACGGCGA


 


1301
AGGCAAGCGG CAACGATGTG GACAGCAAAG GCGCGTCTTC CGCACGTTTC


 


1351
AAAAACCACG CCGACATCAT CGGTCTGCAA TACACCTACA AATTCAAATA


 


1401
A






This corresponds to the amino acid sequence <SEQ ID 2988; ORF 989>:










m989.pep




1
MTPSALKKTV LLLGTAFAAA SVHASGYHFG TQSVNAQSTA NAAAAEAADA


 


51
STIFYNPAGL TKLDSSQISV NANIVLPSIH YEADSATDFT GLPVQGSKSG


 


101
KITKTTVAPH IYGAYKVNDN LTVGLGVYVP FGSATEYEKD SVLRHNINKL


 


151
GLTSIAVEPV AAWKLNDRHS FGAGIIAQHT SAELRKYADW GIKSKAEILT


 


201
AKPPKPNGVA EAAKIQADGH ADVKGSDWGF GYQLAWMWDI NDRARVGVNY


 


251
RSKVSHTLKG DAEWAADGAA AKAMWSTMLA ANGYTANEKA RVKIVTPESL


 


301
SVHGMYKVSD KADLFGDVTW TRHSRFDKAE LVFEKEKTVV KGKSDRTTIT


 


351
PNWRNTYKVG FGGSYQISEP LQLRAGIAFD KSPVRNADYR MNSLPDGNRI


 


401
WFSAGMKYHI GKNHVVDAAY THIHINDTSY RTAKASGNDV DSKGASSARF


 


451
KNHADIIGLQ YTYKFK*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

g989/m989 90.0% identity in 468 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2989>:










a989.seq




1
ATGACCCCTT CCGCACTGAA AAAAACCGTC CTACTGCTCG GCACTGCCTT


 


51
TGCCGCCGCA TCCGCACAAG CCTCCGGCTA CCACTTCGGC ACACAGTCGG


 


101
TCAACGCGCA AAGCACGGCA AATGCCGCCG CCGCAGAAGC CGCCGACGCA


 


151
TCGACCATCT TCTACAACCC TGCCGGCCTG ACCAAACTCG ACAGCAGCCA


 


201
GATTTCCGTC AACGCCAACA TCGTGCTGCC CAGCATTCAT TATGAGGCGG


 


251
ATTCCGCCAC CGACTTTACC GGGCTTCCCG TCCAAGGTTC GAAAAGCGGC


 


301
AAAATCACCA AAACCACGGT CGCGCCCCAC ATCTACGGCG CATACAAAGT


 


351
CAACGACAAT CTGACCGTAG GCTTGGGCGT GTACGTCCCC TTCGGTTCTG


 


401
CCACCGAATA CGAAAAAGAT TCCGTGTTGC GCCACAACAT CAACAAACTC


 


451
GGTCTGACCA GCATCGCCGT CGAACCTGTC GCCGCGTGGA AACTCAACGA


 


501
ACGCCATTCC TTCGGCGCAG GCATCATCGC CCAACATACT TCCGCCGAGC


 


551
TGCGCAAATA TGCCGACTGG GGGATTATGG AAAAAGCGAA AGCACTAAAA


 


601
GAAACACCCC CCAATCCAAC TAAAGCCGCC CAAATCAAAG CCGACGGACA


 


651
CGCCGATGTC AAAGGCAGCG ATTGGGGCTT CGGCTACCAA CTGGCGTGGA


 


701
TGTGGGACAT CAACGACCGT GCGCGCGTGG GCGTGAACTA CCGTTCCAAA


 


751
GTCTCACACA CGCTCAAAGG CGATGCCGAA TGGGCGGCAG ACGACGCAAT


 


801
GGCGAAACAG TTATGGGATG CAAACAAACT CGCACTGCTC GGCTACACGC


 


851
CAAGCGAAAA AGCCCGCGTT AAAATCGTTA CGCCCGAGTC TTTGTCCGTA


 


901
CACGGTATGT ACAAAGTGTC CGACAAAGCC GACCTGTTCG GCGACGTAAC


 


951
TTGGACGCGC CACAGCCGCT TCGATAAGGC GGAACTGGTT TTTGAAAAAG


 


1001
AAAAAACCAT CGTCAACGGC AAATCCGACC GCACCACCAT CACCCCCAAC


 


1051
TGGCGCAACA CCTACAAAGT CGGCTTCGGC GGTTCTTATC AAATCAGCGA


 


1101
ACCGCTGCAA CTGCGCGCCG GCATCGCTTT TGACAAATCG CCCGTCCGCA


 


1151
ACGCCGACTA CCGCATGAAC AGCCTGCCCG ACGGCAACCG CATCTGGTTC


 


1201
TCCGCCGGCA TGAAATACCA TATCGGCAAA AACCACGTCG TCGATGCCGC


 


1251
CTACACCCAC ATCCACATCA ACGACACCAG CTACCGCACG GCGAAGGCAA


 


1301
GCGGCAACGA TGTGGACAGC AAAGGCGCGT CTTCCGCACG TTTCAAAAAC


 


1351
CACGCCGACA TCATCGGCCT GCAATACACC TACAAATTCA AATAA






This corresponds to the amino acid sequence <SEQ ID 2990; ORF 989.a>:










a989.pep




1
MTPSALKKTV LLLGTAFAAA SAQASGYHFG TQSVNAQSTA NAAAAEAADA


 


51
STIFYNPAGL TKLDSSQISV NANIVLPSIH YEADSATDFT GLPVQGSKSG


 


101
KITKTTVAPH IYGAYKVNDN LTVGLGVYVP FGSATEYEKD SVLRHNINKL


 


151
GLTSIAVEPV AAWKLNERHS FGAGIIAQHT SAELRKYADW GIMEKAKALK


 


201
ETPPNPTKAA QIKADGHADV KGSDWGFGYQ LAWMWDINDR ARVGVNYRSK


 


251
VSHTLKGDAE WAADDAMAKQ LWDANKLALL GYTPSEKARV KIVTPESLSV


 


301
HGMYKVSDKA DLFGDVTWTR HSRFDKAELV FEKEKTIVNG KSDRTTITPN


 


351
WRNTYKVGFG GSYQISEPLQ LRAGIAFDKS PVRNADYRMN SLPDGNRIWF


 


401
SAGMKYHIGK NHVVDAAYTH IHINDTSYRT AKASGNDVDS KGASSARFKN


 


451
HADIIGLQYT YKFK*






m989/a989 93.1% identity in 467 aa overlap




The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2991>:










m990.seq




1
ATGTTCAGAG CTCAGCTTGG TTCAAATACT CGTTCTACCA AAATCGGCGA


 


51
CGATGCCGAT TTTTCATTTT CAGACAAGCC GAAACCCGGC ACTTCCCATT


 


101
ATTTTTCCAG CGGTAAAACC GATCAAAATT CATCCGAATA TGGGTATGAC


 


151
GAAATCAATA TCCAAGGTAA AAATTACAAT AGCGGCATCC TCGCCGTCGA


 


201
TAATATGCCC GTTGTCAAAA AATATATTAC AGAGAAGTAT GGGGCTGATT


 


251
TAAAGCAGGC GGTTAAAAGT CAATTACAGG ATTTATACAA AACAAGACCG


 


301
GAAGCTTGGG CAGAAAATAA AAAACGGACT GAGGAGGCGT ATATAGCACA


 


351
GTTTGGAACA AAATTTAGTA CGCTCAAACA GACGATGCCC GATTTAATTA


 


401
ATAAATTGGT AGAAGATTCC GTACTCACTC CTCATAGTAA TACATCACAG


 


451
ACTAGTCTCA ACAACATCTT CAATAAAAAA TTACACGTCA AAATCGAAAA


 


501
CAAATCCCAC GTCGCCGGAC AGGTGTTGGA ACTGACCAAG ATGACGCTGA


 


551
AAGATTCCCT TTGGGAACCG CGCCGCCATT CCGACATCCA TACGCTGGAA


 


601
ACTTCCGATA ATGCCCGCAT CCGCCTGAAC ACGAAAGATG AAAAACTGAC


 


651
CGTCCATAAG GATTATGCGG GCGGCGCGGA TTTCCTGTTC GGCTACGACG


 


701
TGCGGGAGTC GGACGAACCC GCCCTGACCT TTGAAGACAA AGTCAGCGGA


 


751
CAATCCGGCG TGGTTTTGGA ACGCCGGCCG GAAAATCTGA AAACGCTCGA


 


801
CGGGCGCAAA CTGATTGCGG CAAAAACGGC GGATTCCGGT TCGTTTGCGT


 


851
TTAAACAAAA TTACCGGCAG GGACTGTACG AATTATTGCT CAAGCAATGC


 


901
GAAGGCGGAT TTTGCTTGGG CGTGCAGCGT TTGGCTATCC CCGAGGCGGA


 


951
AGCGGTTTTA TATGCCCAAC AGGCTTATGC GGCAAATACT TTGTTTGGGC


 


1001
TGCGTGCCGC CGACAGGGGC GACGACGTGT ATGCCGCCGA TCCGTCCCGT


 


1051
CAAAAATTGT GGCTGCGCTT CATCGGCGGC CGGTCGCATC AAAATATACG


 


1101
GGGCGGCGCG GCTGCGGACG GGTGGCGCAA AGGCGTGCAA ATCGGCGGCG


 


1151
AGGTGTTTGT ACGGCAAAAT GAAGGCAGCC GACTGGCAAT CGGCGTGATG


 


1201
GGCGGCAGGG CCGGCCAGCA CGCATCAGTC AACGGCAAAG GCGGTGCGGC


 


1251
AGGCAGTGAT TTGTATGGTT ATGGCGGGGG TGTTTATGCT GCGTGGCATC


 


1301
AGTTGCGCGA TAAACAAACG GGTGCGTATT TGGACGGCTG GTTGCAATAC


 


1351
CAACGTTTCA AACACCGCAT CAATGATGAA AACCGTGCGG AACGCTACAA


 


1401
AACCAAAGGT TGGACGGCTT CTGTCGAAGG CGGCTACAAC GCGCTTGTGG


 


1451
CGGAAGGCAT TGTCGGAAAA GGCAATAATG TGCGGTTTTA CCTACAACCG


 


1501
CAGGCGCAGT TTACCTACTT GGGCGTAAAC GGCGGCTTTA CCGACAGCGA


 


1551
GGGGACGGCG GTCGGACTGC TCGGCAGCGG TCAGTGGCAA AGCCGCGCCG


 


1601
GCATTCGGGC AAAAACCCGT TTTGCTTTGC GTAACGGTGT CAATCTTCAG


 


1651
CCTTTTGCCG CTTTTAATGT TTTGCACAGG TCAAAATCTT TCGGCGTGGA


 


1701
AATGGACGGC GAAAAACAGA CGCTGGCAGG CAGGACGGCA CTCGAAGGGC


 


1751
GGTTCGGTAT TGAAGCCGGT TGGAAAGGCC ATATGTCCGC ACGCATCGGA


 


1801
TATGGCAAAA GGACGGACGG CGACAAAGAA GCCGCATTGT CGCTCAAATG


 


1851
GCTGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 2992; ORF 990>:










m990.pep




1
MFRAQLGSNT RSTKIGDDAD FSFSDKPKPG TSHYFSSGKT DQNSSEYGYD


 


51
EINIQGKNYN SGILAVDNMP VVKKYITEKY GADLKQAVKS QLQDLYKTRP


 


101
EAWAENKKRT EEAYIAQFGT KFSTLKQTMP DLINKLVEDS VLTPHSNTSQ


 


151
TSLNNIFNKK LHVKIENKSH VAGQVLELTK MTLKDSLWEP RRHSDIHTLE


 


201
TSDNARIRLN TKDEKLTVHK DYAGGADFLF GYDVRESDEP ALTFEDKVSG


 


251
QSGVVLERRP ENLKTLDGRK LIAAKTADSG SFAFKQNYRQ GLYELLLKQC


 


301
EGGFCLGVQR LAIPEAEAVL YAQQAYAANT LFGLRAADRG DDVYAADPSR


 


351
QKLWLRFIGG RSHQNIRGGA AADGWRKGVQ IGGEVFVRQN EGSRLAIGVM


 


401
GGRAGQHASV NGKGGAAGSD LYGYGGGVYA AWHQLRDKQT GAYLDGWLQY


 


451
QRFKHRINDE NRAERYKTKG WTASVEGGYN ALVAEGIVGK GNNVRFYLQP


 


501
QAQFTYLGVN GGFTDSEGTA VGLLGSGQWQ SRAGIRAKTR FALRNGVNLQ


 


551
PFAAFNVLHR SKSFGVEMDG EKQTLAGRTA LEGRFGIEAG WKGHMSARIG


 


601
YGKRTDGDKE AALSLKWLF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2993>:










a990.seq




1
ATGTTCAGAG CTCAGCTTGG TTCAAATACT CGTTCTACCA AAATCGGCGA


 


51
CGATGCCGAT TTTTCATTTT CAGACAAGCC GAAACCCGGC ACTTCCCATT


 


101
ATTTTTCCAG CGGTAAAACC GATCAAAATT CATCCGAATA TGGGTATGAC


 


151
GAAATCAATA TCCAAGGTAA AAACTACAAT AGCGGCATAC TCGCCGTCGA


 


201
TAATATGCCC GTTGTTAAGA AATATATTAC AGATACTTAC GGGGATAATT


 


251
TAAAGGATGC GGTTAAGAAG CAATTACAGG ATTTATACAA AACAAGACCC


 


301
GAAGCTTGGG AAGAAAATAA AAAACGGACT GAGGAGGCGT ATATAGAACA


 


351
GCTTGGACCA AAATTTAGTA TACTCAAACA GAAAAACCCC GATTTAATTA


 


401
ATAAATTGGT AGAAGATTCC GTACTCACTC CTCATAGTAA TACATCACAG


 


451
ACTAGTCTCA ACAACATCTT CAATAAAAAA TTACACGTCA AAATCGAAAA


 


501
CAAATCCCAC GTCGCCGGAC AGGTGTTGGA ACTGACCAAG ATGACGCTGA


 


551
AAGATTCCCT TTGGGAACCG CGCCGCCATT CCGACATCCA TATGCTGGAA


 


601
ACTTCCGATA ATGCCCGCAT CCGCCTGAAC ACGAAAGATG AAAAACTGAC


 


651
CGTCCATAAA GCGTATCAGG GCGGTGCGGA TTTCCTGTTC GGCTACGACG


 


701
TGCGGGAGTC GGACAAACCC GCCCTGACCT TTGAAGAAAA AGTCAGCGGA


 


751
CAATCCGGCG TGGTTTTGGA ACGCCGGCCG GAAAATCTGA AAACGCTCGA


 


801
CGGGCGCAAA CTGATTGCGG CGGAAAAGGC AGACTCTAAT TCGTTTGCGT


 


851
TTAAACAAAA TTACCGGCAG GGACTGTACG AATTATTGCT CAAGCAATGC


 


901
GAAGGCGGAT TTTGCTTGGG CGTGCAGCGT TTGGCTATCC CCGAGGCGGA


 


951
AGCGGTTTTA TATGCCCAAC AGGCTTATGC GGCAAATACT TTGTTCGGGC


 


1001
TGCGTGCCGC CGACAGGGGC GACGACGTGT ATGCCGCCGA TCCGTCCCGT


 


1051
CAAAAATTGT GGCTGCGCTT CATCGGCGGC CGGTCGCATC AAAATATACG


 


1101
GGGCGGCGCG GCTGCGGACG GGCGGCGCAA AGGCGTGCAA ATCGGCGGCG


 


1151
AGGTGTTTGT ACGGCAAAAT GAAGGCAGCC GGCTGGCAAT CGGCGTGATG


 


1201
GGCGGCAGGG CTGGCCAGCA CGCATCAGTC AACGGCAAAG GCGGTGCGGC


 


1251
AGGCAGTTAT TTGCATGGTT ATGGCGGGGG TGTTTATGCT GCGTGGCATC


 


1301
AGTTGCGCGA TAAACAAACG GGTGCGTATT TGGACGGCTG GTTGCAATAC


 


1351
CAACGTTTCA AACACCGCAT CAATGATGAA AACCGTGCGG AACGCTACAA


 


1401
AACCAAAGGT TGGACGGCTT CTGTCGAAGG CGGCTACAAC GCGCTTGTGG


 


1451
CGGAAGGCGT TGTCGGAAAA GGCAATAATG TGCGGTTTTA CCTGCAACCG


 


1501
CAGGCGCAGT TTACCTACTT GGGCGTAAAC GGCGGCTTTA CCGACAGCGA


 


1551
GGGGACGGCG GTCGGACTGC TCGGCAGCGG TCAGTGGCAA AGCCGCGCCG


 


1601
GCATTCGGGC AAAAACCCGT TTTGCTTTGC GTAACGGTGT CAATCTTCAG


 


1651
CCTTTTGCCG CTTTTAATGT TTTGCACAGG TCAAAATCTT TCGGCGTGGA


 


1701
AATGGACGGC GAAAAACAGA CGCTGGCAGG CAGGACGGCG CTCGAAGGGC


 


1751
GGTTCGGCAT TGAAGCCGGT TGGAAAGGCC ATATGTCCGC ACGCATCGGA


 


1801
TACGGCAAAA GGACGGACGG CGACAAAGAA GCCGCATTGT CGCTCAAATG


 


1851
GCTGTTTTGA






This corresponds to the amino acid sequence <SEQ ID 2994; ORF 990.a>:










a990.pep




1
MFRAQLGSNT RSTKIGDDAD FSFSDKPKPG TSHYFSSGKT DQNSSEYGYD


 


51
EINIQGKNYN SGILAVDNMP VVKKYITDTY GDNLKDAVKK QLQDLYKTRP


 


101
EAWEENKKRT EEAYIEQLGP KFSILKQKNP DLINKLVEDS VLTPHSNTSQ


 


151
TSLNNIFNKK LHVKIENKSH VAGQVLELTK MTLKDSLWEP RRHSDIHMLE


 


201
TSDNARIRLN TKDEKLTVHK AYQGGADFLF GYDVRESDKP ALTFEEKVSG


 


251
QSGVVLERRP ENLKTLDGRK LIAAEKADSN SFAFKQNYRQ GLYELLLKQC


 


301
EGGFCLGVQR LAIPEAEAVL YAQQAYAANT LFGLRAADRG DDVYAADPSR


 


351
QKLWLRFIGG RSHQNIRGGA AADGRRKGVQ IGGEVFVRQN EGSRLAIGVM


 


401
GGRAGQHASV NGKGGAAGSY LHGYGGGVYA AWHQLRDKQT GAYLDGWLQY


 


451
QRFKHRINDE NRAERYKTKG WTASVEGGYN ALVAEGVVGK GNNVRFYLQP


 


501
QAQFTYLGVN GGFTDSEGTA VGLLGSGQWQ SRAGIRAKTR FALRNGVNLQ


 


551
PFAAFNVLHR SKSFGVEMDG EKQTLAGRTA LEGRFGIEAG WKGHMSARIG


 


601
YGKRTDGDKE AALSLKWLF*






m990/a990 96.0% identity in 619 aa overlap




The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 2995>:










g992.seq




1
ATGTTCAGAC GGCATCGGCA TTTGAAAAAT ATGCAGATTA AAAAAATCAT


 


51
GAAATGGCTT CCCGTCGCCC TGTCGCTTTT GGGCGCGTTG GGTTATACGG


 


101
GATATGACAG TGAGGCGGTG CGGACGGCGG TTGCCGTACT CGACGTACTC


 


151
GGCACTGCAG GGGACGTGGG TTTCGACGCG CCCGTTCGCC GACGGGCATC


 


201
GGCGAAATCC GGCCACAGCT ACACAGGCAC GGTGTCCAAA GTCTATGACG


 


251
GCGATACCCT TCACGTCATC GACGGCGACG GCGCGAAACA TAAAATTCGG


 


301
ATGGCGTATA TCGACGCACC GGAGATGAAA CAGGCTTACG GTACACGTTC


 


351
GCGCGACAAC CTGCGCGCGG CGGCGGAGGG TAGGAAAGTC AGTGTACGTG


 


401
TGTTTGAAAC CGACCGCTAT CAGCGCGAAG TGGCGCAGGT ATCCGCCGGC


 


451
AAAACCGATT TGAACCTGAT GCAGGTGCAG GACGGGGCGG CGTGGCATTA


 


501
TAAAAGTTAT GCTAAAGAAC AGCAGGATAA GGCGGATTTT GCCGACTATG


 


551
CCGACGCTCA AATTCAGGCG GAAAGGGAAC GCAAAGGATT GTGGAAAGCT


 


601
AAAAATCCGC AAGCGCCGTG GGCGTACCGC CGGGCAGGCA GGAGCGGCGG


 


651
GGGCAATAAG GATTGGATGG ATTCCGTGGG CGAATGGTTG GGCATTTGGT


 


701
AA






This corresponds to the amino acid sequence <SEQ ID 2996 ORF 992.ng>:










g992.pep




1
MFRRHRHLKN MQIKKIMKWL PVALSLLGAL GYTGYDSEAV RTAVAVLDVL


 


51
GTAGDVGFDA PVRRRASAKS GHSYTGTVSK VYDGDTLHVI DGDGAKHKIR


 


101
MAYIDAPEMK QAYGTRSRDN LRAAAEGRKV SVRVFETDRY QREVAQVSAG


 


151
KTDLNLMQVQ DGAAWHYKSY AKEQQDKADF ADYADAQIQA ERERKGLWKA


 


201
KNPQAPWAYR RAGRSGGGNK DWMDSVGEWL GIW*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2997>:










m992.seq




1
ATGTTCAGAC GGCATCGGCA TTTGAAAAAT ATGCAGATTA AAAAAATCAT


 


51
GAAATGGCTT CCCGTCGCCC TGTCGCTTTT GGGTGCGTTG GGTTATACGG


 


101
GGTACGGCAG CGAGGCGGTG CGGACGGCGG TTGCCGTACT CGACGTACTC


 


151
GGCGCGGCAG GGGACGCGGG TTCCGACGCG CCCGCCCGCC GCCGAGCATC


 


201
GGCGAAATCC GGCCACCGCT ACACAGGCAC GGTGTCCAAA GTCTATGACG


 


251
GCGACACCCT TCACGTTATC GACGGCGACG GCGCGAAACA CAAAATCCGG


 


301
ATGGCGTATA TCGACGCGCC GGAGATGAAA CAGGCTTACG GCACGCGTTC


 


351
GCGCGACAAC CTGCGCGCGG CGGCGGAAGG CAGGAAAGTC AGCGTGCGCG


 


401
TGTTCGATAC CGACCGCTAC CAGCGCGAAG TGGCGCAGGT TTCTGTCGGC


 


451
AAAACCGATT TGAACCTGAT GCAGGTGCAG GACGGGGCGG CGTGGCATTA


 


501
TAAAAGTTAT GCTAAAGAAC AGCAGGATAA GGCGGATTTT GCCGATTATG


 


551
CCGACGCTCA AATTCAGGCG GAAAGGGAAC GCAAAGGATT GTGGAAAGCT


 


601
AAAAATCCGC AAGCGCCGTG GGCGTACCGC CGAGCAGGCA GGAGCGGCGG


 


651
GGGCAATAAG GATTGGATGG ATGCCGTGGG CGAATGGTTG GGCATTTGGT


 


701
AA






This corresponds to the amino acid sequence <SEQ ID 2998; ORF 992>:










m992.pep




1
MFRRHRHLKN MQIKKIMKWL PVALSLLGAL GYTGYGSEAV RTAVAVLDVL


 


51
GAAGDAGSDA PARRRASAKS GHRYTGTVSK VYDGDTLHVI DGDGAKHKIR


 


101
MAYIDAPEMK QAYGTRSRDN LRAAAEGRKV SVRVFDTDRY QREVAQVSVG


 


151
KTDLNLMQVQ DGAAWHYKSY AKEQQDKADF ADYADAQIQA ERERKGLWKA


 


201
KNPQAPWAYR RAGRSGGGNK DWMDAVGEWL GIW*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 992 shows 96.1% identity over a 233 aa overlap with a predicted ORF (ORF 992) from N. gonorrhoeae 

m992/g992 96.1% identity in 233 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 2999>:










a992.seq




1
ATGTTCAGAC GGCATCGGCA TTTGAAAAAT ATGCAGATTA AAAAAATCAT


 


51
GAAATGGCTT CCCGTCGCCT TGTCGCTTTT GGGTGCGTTG GGTTATACGG


 


101
GGTACGGCAG CGAGGCGGTG CGGACGGCGG TTGCCGTACT CGACGTACTC


 


151
GGCGCGGCAG GGGACGCGGG TTCCGACGCG CCCGCCCGCC GCCGAGCATC


 


201
GGCGAAATCC GGCCACCGCT ACACAGGCAC GGTGTCCAAA GTCTATGACG


 


251
GCGACACCCT TCACGTTATC GACGGCGACG GCGCGAAACA CAAAATCCGG


 


301
ATGGCGTATA TCGACGCGCC GGAGATGAAA CAGGCTTACG GCACGCGTTC


 


351
GCGCGACAAC CTGCGCGCGG CGGCGGAAGG CAGGAAAGTC AGCGTCCGCG


 


401
TGTTCGACAC CGACCGCTAC CAGCGCGAAG TGGCGCAGGT TTCTGTCGGC


 


451
AAAACCGATT TGAACCTGAT GCAGGTGCAG GACGGGGCGG CGTGGCATTA


 


501
TAAAAGTTAT GCTAAAGAAC AGCAGGATAA GGCGGATTTT GCCGATTATG


 


551
CCGACGCTCA AATTCAGGCG GAAAGGGAAC GCAAAGGATT GTGGAAAGCT


 


601
AAAAATCCGC AAGCGCCGTG GGCGTACCGC CGGGCAGGCA GGAGCGGCGG


 


651
GGGCAATAAG GATTGGATGG ATGCCGTGGG CGAATGGTTG GGCATTTGGT


 


701
AA






This corresponds to the amino acid sequence <SEQ ID 3000; ORF 992.a>:










a992.pep




1
MFRRHRHLKN MQIKKIMKWL PVALSLLGAL GYTGYGSEAV RTAVAVLDVL


 


51
GAAGDAGSDA PARRRASAKS GHRYTGTVSK VYDGDTLHVI DGDGAKHKIR


 


101
MAYIDAPEMK QAYGTRSRDN LRAAAEGRKV SVRVFDTDRY QREVAQVSVG


 


151
KTDLNLMQVQ DGAAWHYKSY AKEQQDKADF ADYADAQIQA ERERKGLWKA


 


201
KNPQAPWAYR RAGRSGGGNK DWMDAVGEWL GIW*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 992 shows 100.0% identity over a 233 aa overlap with a predicted ORF (ORF 992) from N. meningitidis 

a992/m992 100.0% identity in 233 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3001>:










g993.seq




1
CTGAAAGTCG TATTGGGCAG TTTTCAAGGC CCTTTGGATC TGCTGCTCTA


 


51
CCTTATCCGC AAGCAGAACA TCGATGTTCT CGATATTCCG ATGGTGGAAA


 


101
TTACCGGGCA GTATCTGCAC TATATTGCCC AAATGGAAGC CTATCAGTTT


 


151
GATTTGGCGG CGGAATATCT TTTGATGGCG GCAATGCTGA TTGAAATCAA


 


201
ATCGCGCCTG CTGCTGCCGC GTACCGAAGC CGTCGAAGAC GAAGAGGCCG


 


251
ACCCGCGTGC CGAGTTGGTG CGCCGTCTGC TTGCCTACGA GCAAATGAAA


 


301
CTGGCGGCGC AGGGTTTGGA CGCGCTGCCG CGTGCGGGAC GGGATTTCGC


 


351
GTGGGCTTAC CTGCCGCTGG AAATTGCAGC CGAGACGAAG CTGCCCGAGG


 


401
TTTACATCGC CGATTTGATG CAGGCATGGT TGGGCATTCT TTCTCGGGCA


 


451
AAACATACGC GCAGCCACGA AGTAATCCAA GAAACCCTTT CCGTGCGCGC


 


501
GCAAATGACG GCAATCCTGC GCCGTTTGAA CGAACACGGG ATATGCAGGT


 


551
TTCACGCCCT GTTCAATCCC GAACAGGGCG CGGCTTACGT GATCGTCAAC


 


601
TTCATCGCCC TGTTGGAGCT TGCCAAAGAA GGATTGGTCG GAATCGTACA


 


651
GGAAGACGGT TTCGGAGAAA TCCGAATCAG CCTCAATCAT GAGGGGGCGC


 


701
ATTCAGACGG CATTTTCGGC ACACGGGGCG GGCGCGATGT GTTCTAA






This corresponds to the amino acid sequence <SEQ ID 3002 ORF 993.ng>:










g993.pep




1
LKVVLGSFQG PLDLLLYLIR KQNIDVLDIP MVEITGQYLH YIAQMEAYQF


 


51
DLAAEYLLMA AMLIEIKSRL LLPRTEAVED EEADPRAELV RRLLAYEQMK


 


101
LAAQGLDALP RAGRDFAWAY LPLEIAAETK LPEVYIADLM QAWLGILSRA


 


151
KHTRSHEVIQ ETLSVRAQMT AILRRLNEHG ICRFHALFNP EQGAAYVIVN


 


201
FIALLELAKE GLVGIVQEDG FGEIRISLNH EGAHSDGIFG TRGGRDVF*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3003>:










m993.seq




1
TTGAAAGTCG TATTGGGCAG CTTCCAAGGC CCTTTGGATC TACTGCTGTA


 


51
TCTGATCCGC AAACAGAATA TCGACGTACT GGATATTCCG ATGGTGAAGA


 


101
TTACCGAGCA GTATCTGCAC TACATCGCCC AAATAGAAAC CTATCAGTTT


 


151
GATTTGGCGG CGGAATATCT TTTGATGGCA GCAATGCTGA TTGAAATCAA


 


201
ATCGCGCCTG CTGCTGCCGC GTACCGAAAC CGTCGAAGAC GAAGAAGCCG


 


251
ACCCGCGTGC CGAGTTGGTG CGCCGCCTGC TGGCTTACGA ACAGATGAAG


 


301
CTGGCGGCGC AGGGTTTGGA CGCGCTGCCC CGAGCCGGAC GGGATTTCGC


 


351
GTGGGCTTAC CTGCCGCTGG AAATTGCCGT CGAAGCCAAG CTGCCCGAAG


 


401
TCTATATTAC CGACTTGACG CAAGCGTGGC TGGGTATTTT GTCTCGGGCA


 


451
AAACACACGC GCAGCCACGA AGTAATCAAA GAAACCATCT CCGTGCGCGC


 


501
GCAAATGACG GCAATCCTGC GCCGTTTGAA CGGACACGGA ATATGCAGGT


 


551
TTCACGACCT GTTCAATCCC AAACAGGGCG CGGCTTACGT GGTCGTCAAC


 


601
TTCATCGCAC TGTTGGAGCT TGCCAAAGAA GGATTGGTCA GAATCGTGCA


 


651
GGAAGACGGT TTCGGAGAAA TCCGAATCAG CCTCAATCAT GAGGGGGCGC


 


701
ATTCAGACGG CATTTCCGGC ACACGAGGCG GGCGCGATGT GTTCTAA






This corresponds to the amino acid sequence <SEQ ID 3004; ORF 993>:










m993.pep




1
LKVVLGSFQG PLDLLLYLIR KQNIDVLDIP MVKITEQYLH YIAQIETYQF


 


51
DLAAEYLLMA AMLIEIKSRL LLPRTETVED EEADPRAELV RRLLAYEQMK


 


101
LAAQGLDALP RAGRDFAWAY LPLEIAVEAK LPEVYITDLT QAWLGILSRA


 


151
KHTRSHEVIK ETISVRAQMT AILRRLNGHG ICRFHDLFNP KQGAAYVVVN


 


201
FIALLELAKE GLVRIVQEDG FGEIRISLNH EGAHSDGISG TRGGRDVF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 993 shows 93.1% identity over a 248 aa overlap with a predicted ORF (ORF 993) from N. gonorrhoeae 

m993/g993 93.1% identity in 248 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3005>:










a993.seq




1
CTGAAAGTCG TATTGAGCAG TTTTCAAGGC CCTTTGGATC TGCTGCTCTA


 


51
CCTTATCCGC AAGCAGAACA TCGATGTTCT CGATATTCCG ATGGTGAAGA


 


101
TTACCGAACA GTATCTGCAC TACATCGCCC AAATAGAAAC CTATCAGTTT


 


151
GATTTGGCGG CGGAATATCT TTTGATGGCA GCAATGCTGA TTGAAATCAA


 


201
ATCGCGCCTG CTGCTGCCGC GTACCGAAAC CGTCGAAGAC GAAGAAGCCG


 


251
ACCCGCGTGC CGAGTTGGTG CGCCGCCTGC TGGCTTACGA GCAGATGAAG


 


301
CTGGCGGCAC AAGGGTTGGA TGCGCTTCCT CGTGCGGGCC GGGATTTCGC


 


351
ATGGGCATAC CTGCCACTGG AAATTGCCGT CGAAGCCAAG CTGCCCGAAG


 


401
TCTATATTAC CGACTTGACG CAGGCGTGGC TGAGTATTTT GTCTCGGGCA


 


451
AAACATACGC GCAGCCACGA AGTTATCAAA GAAACCATCT CCGTGCGCGC


 


501
GCAAATGACG GCAATCCTGC GCCGTTTGAA CAAACACGGG ATATGCAGGT


 


551
TTCACGACCT GTTCAATCCC GAACAGGGCG CGGCTTACGT GGTCGTCAAC


 


601
TTCATCGCAC TGTTGGAGCT TGCCAAAGAA GGTTTGGTCG GAATCGTACA


 


651
GGAAGTCGGT TTCGGAGAAA TCCGAATCAG CCTCAATCAT GAGGGGGCGC


 


701
ATTCAGACGG CATTTCCGGC ACACGGGGCG GGCGCGATGT GTTCTAA






This corresponds to the amino acid sequence <SEQ ID 3006; ORF 993.a>:










a993.pep




1
LKVVLSSFQG PLDLLLYLIR KQNIDVLDIP MVKITEQYLH YIAQIETYQF


 


51
DLAAEYLLMA AMLIEIKSRL LLPRTETVED EEADPRAELV RRLLAYEQMK


 


101
LAAQGLDALP RAGRDFAWAY LPLEIAVEAK LPEVYITDLT QAWLSILSRA


 


151
KHTRSHEVIK ETISVRAQMT AILRRLNKHG ICRFHDLFNP EQGAAYVVVN


 


201
FIALLELAKE GLVGIVQEVG FGEIRISLNH EGAHSDGISG TRGGRDVF*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 993 shows 97.6% identity over a 248 aa overlap with a predicted ORF (ORF 993) from N. meningitidis 

a993/m993 97.6% identity in 248 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3007>:










g996.seq




1
ATGAACAGAA GAACCTTCCT CCTCGGCGCA GGCGCGTTGC TTCTTACCGC


 


51
CTGCGGCAGA AAATCCGCCC GAACCCACGC CAAAATTCCC GAAGGAAGCA


 


101
CCGTGCTTGC CTTGGGCGAT TCGCTCACCT TCGGCTACGG AGCAAACCCC


 


151
GGCGAATCCT ACCCCGCGCA ACTGCAAAAA CTGACGGGTT GGAATATTGT


 


201
CAACGGCGGC GTATCGGGCG ATACGTCCGC GCAAGCCCTA TCGCGCCTGC


 


251
CCGCGCTGTT GGCACGCAAA CCCAAGCTTG TGATTGTCGG CATAGGCGGC


 


301
AACGACTTTC TGCGCAAAGT TCCCGAGGAG CAGACCCGCG CCAATATCGC


 


351
GAAAATCATC GAAACCGTGC AAAAGGAAAA CATTCCCGCC GTCCTCGTCG


 


401
GCGTGCCGCA CATCACACTG GGCGCGTTGT TCGGGCATTT GAGCGACCAT


 


451
CCGCTGTATG AGGATTTGTC CGAGGAATAC GGCATTCCGT TGTTCGGCGG


 


501
CGCGTGGGCG GAAATTTTGG GCAATAATAA TCTGAAATCC GACCAAATCC


 


551
ACGCCAACGG CAAAGGCTAT CGGAAATTCG CCGAAAATTT GAATCAATTT


 


601
TTGAGAAAAC ATGGGTTTAG ATAA






This corresponds to the amino acid sequence <SEQ ID 3008 ORF 996.ng>:










g996.pep




1
MNRRTFLLGA GALLLTACGR KSARTHAKIP EGSTVLALGD SLTFGYGANP


 


51
GESYPAQLQK LTGWNIVNGG VSGDTSAQAL SRLPALLARK PKLVIVGIGG


 


101
NDFLRKVPEE QTRANIAKII ETVQKENIPA VLVGVPHITL GALFGHLSDH


 


151
PLYEDLSEEY GIPLFGGAWA EILGNNNLKS DQIHANGKGY RKFAENLNQF


 


201
LRKHGFR*






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3009>:










m996.seq




1
ATGAACAGAA GAACCTTCCT CCTCGGCGCA GGCGCGTTGC TGCTTACCGC


 


51
CTGCGGCAGA AAATCCGCCC GAACCCACGC CAAAATTCCC GAAGGAAGCA


 


101
CCGTACTTGC CTTGGGCGAT TCGCTTACCT TCGGCTACGG CGCAAACCCT


 


151
GGCGAATCCT ACCCCGCGCA ACTGCAAAAA CTGACGGGTT GGAATATTGT


 


201
CAACGGCGGC GTATCGGGCG ATACATCTGC CCAAGCCCTG TCGCGCCTGC


 


251
CCGCGCTGTT GGCACGCAAA CCCAAGCTTG TGATTGTCGG CATAGGCGGC


 


301
AACGACTTTC TGCGCAAAGT TCCCAAGGAG CAGACCCGCG CCAATATCGC


 


351
GAAAATCATC GAAACCGTGC AGAAGGAAAA CATCCCCGCC GTCCTCGTCG


 


401
GCGTGCCGCA CATCACACTG GGTGCGTTGT TCGGGCATTT GAGCGATCAT


 


451
CCGCTGTATG AGGATTTGTC CGAGGAATAC GGCATTCCGC TGTTCGGCGG


 


501
CGCGTGGGCG GAAATTTTGG GCGATAATAA TCTGAAATCC GACCAAATCC


 


551
ACGCCAACGG CAAAGGCTAT CGGAAATTTG CCGAAGATTT GAATCAATTT


 


601
TTGAGAAAAC AGGGGTTTAG ATAA






This corresponds to the amino acid sequence <SEQ ID 3010; ORF 996>:










m996.pep




1
MNRRTFLLGA GALLLTACGR KSARTHAKIP EGSTVLALGD SLTFGYGANP


 


51
GESYPAQLQK LTGWNIVNGG VSGDTSAQAL SRLPALLARK PKLVIVGIGG


 


101
NDFLRKVPKE QTRANIAKII ETVQKENIPA VLVGVPHITL GALFGHLSDH


 


151
PLYEDLSEEY GIPLFGGAWA EILGDNNLKS DQIHANGKGY RKFAEDLNQF


 


201
LRKQGFR






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 996 shows 98.1% identity over a 207 aa overlap with a predicted ORF (ORF 996) from N. gonorrhoeae 

m996/g996 98.1% identity in 207 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3011>:










a996.seq




1
ATGAACAGAA GAACCTTCCT CCTCGGCGCA GGCGCGTTGC TCCTTACCGC


 


51
CTGCGGCAGA AAATCCGCCC GAACCCACGC CAAAATTCCC GAAGGAAGCA


 


101
CCGTACTTGC CTTGGGCGAT TCGCTTACCT TCGGCTACGG CGCAAACCCC


 


151
GGCGAATCCT ACCCCGCGCA ACTGCAAAAA CTGACGGGTT GGAATATTGT


 


201
CAACGGCGGC GTATCGGGCG ATACATCCGC CCAAGCCCTG TCGCGCCTGC


 


251
CCGCGCTGTT GGCACGCAAA CCCAAGCTTG TGATTGTCGG CATAGGCGGC


 


301
AACGACTTTC TGCGCAAAGT TCCCAAGGAG CAGACCCGCG CCAATATCGC


 


351
GAAAATCATC GAAACCGTGC AGAAGGAAAA CATCCCCGCC GTCCTCGTCG


 


401
GCGTGCCGCA CATTACCTTG GGCGCGTTGT TCGGGCATTT GAGCGATCAT


 


451
CCGCTGTATG AGGATTTGTC CGAGGAATAC GGCATTCCGC TGTTCGGCGG


 


501
CGCGTGGGCG GAAATTTTGG GCGATAATAA TCTGAAATCC GACCAAATCC


 


551
ACGCCAACGG CAAAGGCTAT CGGAAATTTG CCGAAGATTT GAATCAATTT


 


601
TTGAGAAAAC AGGGGTTTAG ATAA






This corresponds to the amino acid sequence <SEQ ID 3012; ORF 996.a>:










a996.pep




1
MNRRTFLLGA GALLLTACGR KSARTHAKIP EGSTVLALGD SLTFGYGANP


 


51
GESYPAQLQK LTGWNIVNGG VSGDTSAQAL SRLPALLARK PKLVIVGIGG


 


101
NDFLRKVPKE QTRANIAKII ETVQKENIPA VLVGVPHITL GALFGHLSDH


 


151
PLYEDLSEEY GIPLFGGAWA EILGDNNLKS DQIHANGKGY RKFAEDLNQF


 


201
LRKQGFR*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 996 shows 100.0% identity over a 207 aa overlap with a predicted ORF (ORF 996) from N. meningitidis 

a996/m996 100.0% identity in 207 aa overlap





The following partial DNA sequence was identified in N. gonorrhoeae <SEQ ID 3013>:









g997.seq (partial)










1
ATGATGAACA CGCCGCATCC GCGCCCGAAA ATCGCCGTCA TCGGCGCAGG



 


51
CTGGGCCGGC TTGTCCGCCG CCGTCACCTT GGCGCGGCAC GCCGACGTTA


 


101
CCCTGTTTGA AGCCGGCCGG CAGGCGGGCG GAAGGGCGCG CACACTGGCC


 


151
GGAAATACCG ACGGTTTCGG TTTTTTGGAC AACGGGCAGC ACATTTTGCT


 


201
CGGCGCATAC CGGGGCGTGT TGCGCCTGAT GAAAACCATC GGTTCAGACC


 


251
CCCGTGCCGC CTTTTTGCGC GTACCGCTGC ACTGGCATAT GCACGGCGGT


 


301
TTGCAGTTCC GCGCCCTCCC CCTGCCCGCG CCGCTGCATA TTTTGGGCGG


 


351
CGTGCTGCTT GCCCGGCGCG TACCGTCCGC ATTCAAAGCC AAACTGCTTG


 


401
CCGATATGTC CGATTTGCAG AAGTCCGCAC GCCTCGGACA GCCCGACACG


 


451
ACAGTTGCAC AATGGCTGAA ACAGCGGAAC GTGCCGCGTG CCGCCGTAAT


 


501
GCAGTTTTGG CAGCCCTTGG TCTGGGGCGC GCTCAACACG CCTTTGGAAA


 


551
CCGCAAGCCT GCGCGTGTTG TGCAACGTTT TGTCCGACGG CGTGCTGACG


 


601
AAAAAATCCG GCAGCGACTA TCTCCTACCC AAACAGGATT TGGGCGCAAT


 


651
CGTCGCCGAA CCCGCCTTGG CGGAGCTTCA ACGGCTCGGC GCGGACATCC


 


701
GCCTCGAAAC GCGCGTATGC CGTCTGAACA CCCTCCCGGA CGGAAAAGTC


 


751
CTCGTCAACG GCGAAGCCTT CGATGCCGCC ATACTTGCCA CCGCGCCCTA


 


801
CCACGCCGCC GCGCTCCTGC CCGAAGGCAC GCCCGAACAC GTTCAGACGG


 


851
CATATCAAAA CCTTCGCTAC CACGCCATCA CCACCGTCTA TCTGCGCTAC


 


901
GCCGAACCCG TCCGcCTGCc CGCCCCGCTG ACcGGCATtg CCGAcggcAC


 


951
ggcaCaatgG CTGCTTTgcc cgGGGCAGGC tccggactgc CcccaaAacg


 


1001
aagTCTCCGC cGTCAttagc GTTTCCGAcc GCGtcggcgC Gtttgcaaac


 


1051
cga...






This corresponds to the amino acid sequence <SEQ ID 3014 ORF 997.ng>:









g997.pep (partial)










1
MMNTPHPRPK IAVIGAGWAG LSAAVTLARH ADVTLFEAGR QAGGRARTLA



 


51
GNTDGFGFLD NGQHILLGAY RGVLRLMKTI GSDPRAAFLR VPLHWHMHGG


 


101
LQFRALPLPA PLHILGGVLL ARRVPSAFKA KLLADMSDLQ KSARLGQPDT


 


151
TVAQWLKQRN VPRAAVMQFW QPLVWGALNT PLETASLRVL CNVLSDGVLT


 


201
KKSGSDYLLP KQDLGAIVAE PALAELQRLG ADIRLETRVC RLNTLPDGKV


 


251
LVNGEAFDAA ILATAPYHAA ALLPEGTPEH VQTAYQNLRY HAITTVYLRY


 


301
AEPVRLPAPL TGIADGTAQW LLCPGQAPDC PQNEVSAVIS VSDRVGAFAN


 


351
R....






The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3015>:










m997.seq




1
ATGATGAACA CGCCGCATCC GCGCCCGAAA ATCGCCGTCA TCGGCGCAGG


 


51
CTGGGCAGGA CTGTCCGCCG CCGTCACCTT GGCGCGGCAC GCCGACGTTA


 


101
CCCTGTTTGA AGCCGGCCGG CAGGCGGGCG GCAGGGCGCG CACACTGGCC


 


151
GGAAATACCG ACGGTTTCGG TTTTTTGGAC AACGGGCAGC ACATTTTGCT


 


201
CGGCGCATAC CGGGGCGTGT TGCGCCTGAT GAAAACCATC GGTTCGGATC


 


251
CCCGTGCCGC CTTTTTGCGC GTACCGCTGC ACTGGCATAT GCACGGCGGT


 


301
TTGCAGTTCC GCGCCCTCCC CCTGCCCGCG CCGCTGCATA TTTTGGGCGG


 


351
CGTGCTGCTT GCCCGGCGTG CACCGACTGC ATTCAAAGCC AAACTGCTTG


 


401
CCGATATGTC CGATTTGCAG AAGTCCGCAC GCCTCGGACA GCCCGACACG


 


451
ACAGTGGCGC AATGGCTGAA ACAGCGGAAC GTGCCGCGTG CCGCCGTGAT


 


501
GCAGTTTTGG CAGCCCTTGG TTTGGGGCGC GCTCAACACG CCTTTGGAAA


 


551
CCGCAAGCCT GCGCGTGTTG TGCAACGTTT TGTCCGACGG CGTGCTGACG


 


601
AAAAAATCCG GCAGCGACTA TCTCCTACCC AAGCAGGATT TGGGCGCAAT


 


651
CGTCGCCGAA CCCGCCTTGG CGGATCTTCA ACGGCTCGGC GCGGACATCC


 


701
GCCTCGAAAC GCGCGTATGC CGTCTGAACA CCCTCCCGGA CGGGAAAGTG


 


751
CTCGTCAACG GCGAAGCTTT CGATGCCGCC GTCCCCGCCA CCGCGCCCTA


 


801
CCACGCCGCC GCGCTCCTGC CCGAAGGCAC GCCCGAACAC GTTCAGACGG


 


851
CATATCAAAA CCTTCGCTAC CACGCCATCA CCACCGTCTA TCTGCGCTAC


 


901
GCCGAACCCG TCCGCCTGCC CGCCCCGCTG ACCGGCCTTG CCGACGGCAC


 


951
GGTGCAATGG CTGCTTTGCC GGGGCAGGCT CGGACTGCCT GAAAACGAAG


 


1001
TGTCCGCCGT CATCAGCGTT TCCGACCGCG TCGGCGCGTT TGCAAACCGG


 


1051
GCGTGGGCGG ACAAAGCCCA CGCCGACCTC AAACGCATCC TTCCGCATTT


 


1101
GGGCGAACCC GAAGCCGTGC GCGTCATCAC CGAAAAACGC GCCACAACCG


 


1151
CAGCCGATGC CCCGCCGCCG GACTTGTCGT GGTTGCACCG GCACCGCATC


 


1201
TTCCCCGCCG GCGACTACCT CCACCCGGAC TACCCCGCCA CGCTCGAAGC


 


1251
CGCCGTACAA TCAGGTTTCG CGTCGGCGGA AGCCTGCCTG CAAAGCCTGA


 


1301
GCGATGCCGT CTGA






This corresponds to the amino acid sequence <SEQ ID 3016; ORF 997>:










m997.pep




1
MMNTPHPRPK IAVIGAGWAG LSAAVTLARH ADVTLFEAGR QAGGRARTLA


 


51
GNTDGFGFLD NGQHILLGAY RGVLRLMKTI GSDPRAAFLR VPLHWHMHGG


 


101
LQFRALPLPA PLHILGGVLL ARRAPTAFKA KLLADMSDLQ KSARLGQPDT


 


151
TVAQWLKQRN VPRAAVMQFW QPLVWGALNT PLETASLRVL CNVLSDGVLT


 


201
KKSGSDYLLP KQDLGAIVAE PALADLQRLG ADIRLETRVC RLNTLPDGKV


 


251
LVNGEAFDAA VPATAPYHAA ALLPEGTPEH VQTAYQNLRY HAITTVYLRY


 


301
AEPVRLPAPL TGLADGTVQW LLCRGRLGLP ENEVSAVISV SDRVGAFANR


 


351
AWADKAHADL KRILPHLGEP EAVRVITEKR ATTAADAPPP DLSWLHRHRI


 


401
FPAGDYLHPD YPATLEAAVQ SGFASAEACL QSLSDAV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. gonorrhoeae 

ORF 997 shows 96.0% identity over a 351 aa overlap with a predicted ORF (ORF 997) from N. gonorrhoeae 

g997/m997 96.0% identity in 351 aa overlap





The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3017>:










a997.seq




1
ATGATGAACA CGCCGCATCC GCGCCCGAAA ATCGCCGTCA TCGGCGCAGG


 


51
CTGGGCCGGC TTGTCCGCCG CCGTTACCTT GGCGCGGCAC GCCGACGTTA


 


101
CCCTGTTTGA AGCCGGCCGG CAGGCGGGCG GCAGGGCGCG CGCACTGGCC


 


151
GGAAATACCG ACGGTTTCGG TTTTTTGGAC AACGGGCAGC ATATTTTACT


 


201
CGGCGCATAC CGGGGCGTGT TGCGCCTGAT GAAAACCATC GGTTCAGACC


 


251
CCCATGCCGC CTTTTTGCGC GTACCGCTGC ACTGGCATAT GCACGGCGGT


 


301
TTGCAGTTCC GCGCCCTCCC CCTGCCCGCG CCCCTGCATA TTTTGGGCGG


 


351
CGTGCTGCTT GCCCGGCGCG TACCGTCCGC ATTCAAAGCC AAACTGCTTG


 


401
CCGATATGTC CGATTTGCAG AAGTCCGCAC GCCTCGGACA GCCCGACACG


 


451
ACAGTGGCGC AATGGCTGAA ACAGCGGAAC GTGCCGCGTG CCGCCGTAAT


 


501
GCAGTTTTGG CAGCCCTTGG TTTGGGGCGC GCTCAACACG CCTTTGGAAA


 


551
CCGCAAGCCT GCGCGTGTTG TGCAACGTTT TGTCCGACGG CGTGCTGACG


 


601
AAAAAATCCG GCAGCGACTA TCTCCTACCC AAACAGGATT TGGGCGCAAT


 


651
CGTCGCCGAA CCCGCCTTGG CGGAGCTTCA ACGGCTCGGC GCGGACATCC


 


701
GCCTCGAAAC GCGCATATGC CGTCTGAACA CCCTCCCGGA CGGGAAAGTG


 


751
CTCGTCAACG GCGAACCTTT CGATGCCGCC GTCCCCGCCA CCGCGCCCTA


 


801
CCACGCCGCC GCGCTCCTGC CCGAAGGCAC GCCCGAACAC GTTCAGACGG


 


851
CATATCAAAA CCTTCGCTAT CACGCCATCA CCACCGTCTA TCTGCGCTAT


 


901
GCCGAACCCG TCCGCTTGCC TGCCCCGCTG ACCGGACTTG CCGACGGCAC


 


951
GGTGCAATGG CTGCTTTGCC GGGGCAGGCT CGGACTGCCT GAAAACGAAG


 


1001
TGTCCGCCGT CATCAGCGTT TCCGACCGCG TCGGCGCGTT TGCAAACCGG


 


1051
GCGTGGGCGG ACAAAGTTCA CGCCGACCTC AAACGCATCC TTCCGCATTT


 


1101
GGGCGAACCC GAAGCCGTGC GCGTCATCAC CGAAAAACGC GCCACAACCG


 


1151
CAGCCGATGC CCCGCCGCCG GATTTGTCGT GGTTGCACCG GCACCGCATC


 


1201
TTCCCCGCCG GCGACTACCT CCACCCAGAC TACCCCGCCA CGCTCGAAGC


 


1251
CGCCGTACAA TCAGGTTTCG CGTCGGCGGA AGCCTGCCTG CAAAGCCTGA


 


1301
GCGATGCCGT CTGA






This corresponds to the amino acid sequence <SEQ ID 3018; ORF 997.a>:










a997.pep




1
MMNTPHPRPK IAVIGAGWAG LSAAVTLARH ADVTLFEAGR QAGGRARALA


 


51
GNTDGFGFLD NGQHILLGAY RGVLRLMKTI GSDPHAAFLR VPLHWHMHGG


 


101
LQFRALPLPA PLHILGGVLL ARRVPSAFKA KLLADMSDLQ KSARLGQPDT


 


151
TVAQWLKQRN VPRAAVMQFW QPLVWGALNT PLETASLRVL CNVLSDGVLT


 


201
KKSGSDYLLP KQDLGAIVAE PALAELQRLG ADIRLETRIC RLNTLPDGKV


 


251
LVNGEPFDAA VPATAPYHAA ALLPEGTPEH VQTAYQNLRY HAITTVYLRY


 


301
AEPVRLPAPL TGLADGTVQW LLCRGRLGLP ENEVSAVISV SDRVGAFANR


 


351
AWADKVHADL KRILPHLGEP EAVRVITEKR ATTAADAPPP DLSWLHRHRI


 


401
FPAGDYLHPD YPATLEAAVQ SGFASAEACL QSLSDAV*






Computer analysis of this amino acid sequence gave the following results:

Homology with a predicted ORF from N. meningitidis 

ORF 997 shows 98.2% identity over a 437 aa overlap with a predicted ORF (ORF 997) from N. meningitidis 

a997/m997 98.2% identity in 437 aa overlap





g999.seq Not found yet

g999.pep Not found yet

The following partial DNA sequence was identified in N. meningitidis <SEQ ID 3019>:










m999.seq




1
ATGAATATGA AAAAATTGAT TTCCGCAATT TGTGTTTCAA TTGTTTTATC


 


51
AGCCTGCAAC CAACAATCAA AAACGGCACA AGCCGAAGAA CCTGTCCAAA


 


101
GTATCCAGGC TGCTGATTGT ACCGCCCCAA TGGACATCAC AGTTGAACAA


 


151
TATCTCATCA ATTTGGAGCA AGCATTTAAA ACTCAGAACG TCTCAACAAA


 


201
AATCCATAAT AAAAATATTG TCAAGACCGA TTGTGGTTAT GACCTTACTT


 


251
TGGTAATGGA TTTTGGGGCG ATTGCGCTCA AACTGGACGA GCAGCAAAAA


 


301
ATTAGAGCTA TCTCAGTAGG CTACATTTTA AAAACCGACG GAGAGAAAGG


 


351
ACAAAATCTA GTCAATAATG CCATAAATGG ATTACACAGT ATTCAGGCAG


 


401
TTCTGTCTTT AACTACCACA GACAAATTGG GCGAATCGGA AGCAGGAAAA


 


451
CAACTTTTTA CAGCTTTAAC CGAAGTCGTC AAAGAATCCA ATCAGACAGG


 


501
AGCAACAGCG CAAAAAGACG TTCCGGCAGA TGGTATTTTA TATAGCGTTG


 


551
TTTTTGAAAA AGAAACAAAC ACCATTGCAA TAATCGGCAG AAAACAACCC


 


601
TAA






This corresponds to the amino acid sequence <SEQ ID 3020; ORF 999>:










m999.pep




1
MNMKKLISAI CVSIVLSACN QQSKTAQAEE PVQSIQAADC TAPMDITVEQ


 


51
YLINLEQAFK TQNVSTKIHN KNIVKTDCGY DLTLVMDFGA IALKLDEQQK


 


101
IRAISVGYIL KTDGEKGQNL VNNAINGLHS IQAVLSLTTT DKLGESEAGK


 


151
QLFTALTEVV KESNQTGATA QKDVPADGIL YSVVFEKETN TIAIIGRKQP


 



*






a999.seq Not found yet

a999.pep Not found yet

The foregoing examples are intended to illustrate but not to limit the invention.

## Claims

1. A method of preparing an immunogenic composition comprising:
(a) expressing in E. coli a polypeptide comprising a fragment of the amino acid sequence of SEQ ID NO: 2536, wherein the fragment comprises 16 or more consecutive amino acids from the amino acid sequence, wherein the polypeptide is immunogenic;
(b) purifying the polypeptide;
(c) preparing the immunogenic composition by combining the purified polypeptide with an aluminum salt adjuvant.

2. The method of claim 1, wherein the fragment comprises 20 or more consecutive amino acids from the amino acid sequence of SEQ ID NO: 2536.

3. The method of claim 1, wherein the immunogenic composition further comprises a pharmaceutically acceptable carrier.

4. The method of claim 1, wherein the aluminum salt is aluminum phosphate.

5. The method of claim 3, wherein the aluminum salt is aluminum phosphate.

6. The method of claim 1, wherein the immunogenic composition further comprises a pH buffering agent.

7. The method of claim 6, wherein the immunogenic composition further comprises a pH buffering agent.

8. A method of preparing an immunogenic composition comprising combining a purified polypeptide with an aluminum salt adjuvant, wherein the purified polypeptide was expressed in, and purified from, E. coli; comprises a fragment of the amino acid sequence of SEQ ID NO: 2536, wherein the fragment comprises 16 or more consecutive amino acids from the amino acid sequence; and is immunogenic.

9. The method of claim 8, wherein the fragment comprises 20 or more consecutive amino acids from the amino acid sequence of SEQ ID NO: 2536.

10. The method of claim 8, wherein the immunogenic composition further comprises a pharmaceutically acceptable carrier.

11. The method of claim 8, wherein the aluminum salt is aluminum phosphate.

12. The method of claim 10, wherein the aluminum salt is aluminum phosphate.

13. The method of claim 8, wherein the immunogenic composition further comprises a pH buffering agent.

14. The method of claim 12, wherein the immunogenic composition further comprises a pH buffering agent.