# Patent

## Title
Cleansing composition comprising a cationic and nonionic surfactant mixture

## Abstract

An aqueous cleansing composition comprising a cationic surfactant, a nonionic surfactant, and a thickener comprising an alkoxylated methyl glucose ether, wherein a weight ratio of cationic surfactant to nonionic surfactant is greater than 0.9:1. The combination of the cationic:nonionic surfactant ratio with the alkoxylated methyl glucose ether thickener provides the composition with cold weather stability. Cold weather stability is observed when the composition remains transparent after cold storage.

## Background
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a United States Non-Provisional Patent Application under 35 U.S.C. §111(a) claiming the benefit under 35 U.S.C. §365(c) of PCT Application No. PCT/US2013/061801, filed on Sep. 26, 2013, the contents of which is incorporated herein by reference in its entirety.
BACKGROUND
Cationic surfactants can provide antibacterial properties to a cleansing composition. When cationic surfactants are mixed with nonionic surfactants, there is generally a need to use thickeners to increase the viscosity to a level that is expected by consumers for a cleansing composition, such as a liquid hand soap or body wash. While polyacrylate thickeners can increase the viscosity, they can make the cleansing composition opaque or translucent. It would be desirable to provide a cleansing composition containing cationic and nonionic surfactants that is transparent.
BRIEF SUMMARY
An aqueous cleansing composition comprising a cationic surfactant, a nonionic surfactant, and a thickener comprising an alkoxylated methyl glucose ether, wherein a weight ratio of cationic surfactant to nonionic surfactant is greater than 0.9:1.
The combination of the cationionic:nonionic surfactant ratio with the alkoxylated methyl glucose ether thickener provides the composition with cold weather stability. Cold weather stability is observed when the composition remains transparent after cold storage.
Further areas of applicability of the present invention will become apparent from the detailed description provided hereinafter, It should be understood that the detailed description and specific examples. While indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.


DETAILED DESCRIPTION
The following description of the preferred embodiment(s) is merely exemplary in nature and is in no way intended to limit the invention, its application, or uses.
As used throughout, ranges are used as shorthand for describing each and every value that is within the range. Any value within the range can be selected as the terminus of the range. In addition, all references cited herein are hereby incorporated by referenced in their entireties. In the event of a conflict in a definition in the present disclosure and that of a cited reference, the present disclosure controls.
Unless otherwise specified, all percentages and amounts expressed herein and elsewhere in the specification should be understood to refer to percentages by weight. The amounts given are based on the active weight of the material.
For the purpose of calculating a cationic surfactant to nonionic surfactant ratio, cationic surfactant does not include a cationic antibacterial agent selected from the group consisting of benzalkonium chloride, benzethonium chloride, and mixtures thereof. While these materials may function as a cationic surfactant, they are not included in the calculation.
Transparency is defined as the ability to read 12-point font through the composition contained in a 4 oz clear, glass sample bottle of 4 cm thickness. Transparency is measured after 24 hours at 4.5° C.
Viscosity is measured using a Brookfield RVT viscometer with spindle #5 at 25 rpm at 25′′C.
The composition includes a cationic surfactant. The cationic surfactant can be any cationic surfactant, but it excludes the cationic bacterial agent for weight ratio calculation. In certain embodiments, the cationic surfactant comprises a quaternary ammonium alkyl salt. The quaternary ammonium alkyl salt can be an alkyltrimethylammonium salts. The salt can be a halide; such as chloride or bromide. Or a methosulfate. The alkyl can be a C8-C24 alkyl or a C14-C18 alkyl. In certain embodiments, the cationic surfactant is cetyltrimethylammonium chloride.
In certain embodiments, the cationic surfactant is present in an amount of 0.1 to 20 weight of the composition. In other embodiments, the amount is 0.1 to 10, 0.1 to 5, 0.5 to 10, 0.5 to 5, 1 to 5, or 2 to 4 weight %.
The composition includes a nonionic surfactant, The nonionic Surfactants can be an nonionic surfactant. Nonionic surfactants include, but are not limited to, amine oxides, fatty acid amides, ethoxylated fatty alcohols, block copolymers of polyethylene glycol and polypropylene glycol, glycerol alkyl esters, alkyl polyglucosides, polyoxyethytene glycol octylphenol ethers, sorbitan alkyl esters, polyoxyethylene glycol sorbitan alkyl esters, and mixtures thereof. Examples of amine oxides include, but ate not limited to, laurylamidopropyl dimethylamine oxide, myristylamidopropyl dimethylamine oxide, and mixtures thereof. Examples of fatty acid amides include, but are not limited to, cocomonoethanolatnide, lauramide monoethanolamide, cocodiethanolamide, and mixtures thereof.
In certain embodiments, the nonionic surfactant is a combination of an amine oxide and a fatty acid amide. In certain embodiments, the amine oxide is a mixture of laurylamidopropyl dimethylamine oxide and myristylamidopropyl dimethylamine oxide. In certain embodiments, the nonionic surfactant is a combination of lauryl/myristylamidopropyl dimethylamine oxide and cocomonoethanolamide.
In certain embodiments, the nonionic surfactant is present in an amount of 0.1 to 20 weight % of the composition. In other embodiments, the amount is 0.1 to 10, 0.1 to 5, 0.5 to 10, 0.5 to 5, or 0.5 to 3 weight %.
The composition has a cationic:nonionic weight ratio greater than 0.9:1. Optionally, the ratio is at least 1:1.
In certain embodiments, the composition does not contain an anionic surfactant.
The composition also includes a thickener comprising an alkoxylated methyl glucose ether. The alkoxylation can be ethoxylated and/or propoxylated. In certain embodiments, it is ethoxylated. The degree of alkoxylation can be any degree that provides thickening. In certain embodiments, the degree of alkoxylation is 100 to 200. hi certain embodiments, the alkoxylation is 120 to 150. The alkoxylated methyl glucose ether can be esterified with fatty acid. In certain embodiments, the alkoxylated methyl glucose ether at least one of an alkoxylated methyl glucose dioleate, an alkoxylated methyl glucose trioleate, alkoxylated methyl glucose distearate. In certain embodiments, the alkoxylated methyl glucoside is at least one of PEG-1.20 methyl glucose dioleate, PEG-120 methyl glucose trioleate. PEG-120 methyl glucose distearate. In certain embodiments, the alkoxylated methyl glucose ether is PEG-120 methyl glucose dioleate.
The thickener can be present in any amount to provide any desired viscosity level. In certain embodiments, the thickener is present in an amount of 0.1 to 2 weight % of the composition. In other embodiments, the amount is 0.1 to 1, 0.2 to 1, 0.3 to 1, 0.4 to 1, 0.1 to 0.9, 0.1 to 0.8, 0.1 to 0.7, 0.3 to 0.8, or 0.4 to 0.8 weight %. In one embodiment, the amount is 0.4 to 0.7 weight %. In certain embodiments, the viscosity is at least 1000 mPas. In other embodiments, the viscosity is at least 2000, at least 3000, or at least 4000 mPas. In certain embodiments, the viscosity is 1000 to 20000, 3000 to 6000, or 3500 to 5000 mPas.
In certain embodiments, the composition does not include a polyacrylate thickener.
The composition can include a cationic antibacterial agent selected from the group consisting of benzalkonium chloride, benzethonium chloride, and mixtures thereof. In certain embodiments, the composition includes benzalkonium chloride. These cationic antibacterial agents can be included in their regulatory amount, which can be 0.13 weight %.
The composition is aqueous. In certain embodiments, water can be included in an amount of 70 to 95 weight % of the composition. In other embodiments, the amount of water is 90 to 95 weight %.
In certain embodiments, the composition can further include salt, such as sodium chloride to assist in increasing viscosity at upper ranges of viscosity. In certain embodiments, the salt is present at 0.1 to 1.2 weight % of the composition. In certain embodiments, the amount is about 0.6 weight %.
The cleansing compositions can be used to cleanse skin by washing skin with the cleansing composition and optionally rinsing with water.
EXAMPLES
The examples and comparative examples are made by mixing of the materials. The compositions are shown in Tables I and 2 below. The examples list the cationic:nonionic surfactant ratio. The viscosity and the transparency after storage at 4.5° C. are measured.










TABLE 1





Material
Example 1
Example 2
Example 3







Deionized Water and minors
QS
QS
QS


Lauryl/Myristylamidopropyl
1.68
1.68
0.6


dimethylamine oxide





Cocomonoethanolamide
0.92
1.02
0.4


Cetrimonium chloride
2.75
2.5
3


Benzalkonium chloride
0.13
0.13
0.13


PEG 120 Methyl Glucose
0.54
0.6
0.54


Dioleate





Glycerin
2
2
2


Sodium chloride
0.62
0.62
0.62


Cationic:Nonionic
1.06:1
0.92:1
3:1


surfactant ratio





Transparency after cold
Clear
Clear
Clear


storage





Viscosity (mPas)
4340
4740
5210




















TABLE 2






Compar-
Compar-
Compar-
Compar-



ative
ative
ative
ative


Material
A
B
C
D







Deionized Water and minors
QS
QS
QS
QS


Lauryl/Myristylamidopropyl
1.68
1.51
1.68
2


dimethylamine oxide






Cocomonoethanolaimde
1.1
1.12
1.12
1


Cetrimonium chloride
2.25
2.25
2.25
1


Benzalkonium chloride
0.13
0.13
0.13
0.13


PEG 120 Methyl Glucose
0.66
0.66
0.54
0.6


Dioleate






Glycerin
2
2
2
2


Sodium chloride
0.62
0.62
0.62
0.62


Cationic:Nonionic
0.81:1
0.85:1
0.80:1
0.33:1


surfactant ratio






Transparency after cold
Hazy
Hazy
Hazy
Hazy


storage






Viscosity (mPas)
4600
4000
4340
4470









As can be seen in the examples, the combination of the PEG 20 methyl glucose dioleate and the cationic:nonionic surfactant ratio provides a composition that is clear after cold storage and has a desired viscosity over 4000 mPas. When PEG 20 methyl glucose dioleate is present in all compositions, a desired viscosity is obtained, but when the cationic:nonionic surfactant ratio is less than 0.9 in the comparative examples, the composition is hazy after cold storage.

## Claims

1. An aqueous cleansing composition comprising
a) a cationic surfactant comprising cetyltrimethylammonium chloride,
b) a nonionic surfactant comprising at least one surfactant chosen from an amine oxide and a fatty acid amide, and
c) a thickener comprising at least one of an alkoxylated methyl glucose ether and PEG-150 distearate,
wherein a weight ratio of cationic surfactant to nonionic surfactant is greater than 0.9:1.

2. The cleansing composition of claim 1 further comprising a cationic antibacterial agent selected from the group consisting of benzalkonium chloride, benzethonium chloride, and mixtures thereof.

3. The cleansing composition of claim 2, wherein the cationic antibacterial agent is benzalkonium chloride.

4. The cleansing composition of claim 1, wherein the nonionic surfactant comprises cocomonoethanolamide.

5. The cleansing composition of claim 1, wherein the thickener is an alkoxylated methyl glucose ether esterified with fatty acid.

6. The cleansing composition of claim 5, wherein the thickener is selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-150 distearate, and mixtures thereof.

7. The cleansing composition of claim 6, wherein the thickener is PEG-120 methyl glucose dioleate.

8. The cleansing composition of claim 1, wherein the nonionic surfactant comprises a mixture of laurylamidopropyl dimethylamine oxide, myristylamidopropyl dimethylamine oxide, and cocomonoethanolamide.

9. The cleansing composition of claim 1, wherein the thickener is present in an amount of 0.1 to 2 weight % of the composition.

10. The cleansing composition of claim 1, wherein th cetyltrimethylammonium chloride is present in an amount of 1 to 5 weight % of the composition.

11. The cleansing composition of claim 1, wherein the nonionic surfactant is present in an amount of 0.5 to 5 weight % of the composition.

12. The cleansing composition of claim 1, wherein an amount of water is 70 to 95 weight % of the composition.

13. The cleansing composition of claim 1, further comprising a salt, optionally in an amount of 0.1 to 1.2 weight % of the composition.

14. The cleansing composition of claim 1, wherein the composition does not contain a polyacrylate.

15. The cleansing composition of claim 1, wherein the composition is transparent after 24 hours at 4.5° C.

16. The cleansing composition of claim 1, wherein the composition does not contain an anionic surfactant.

17. The cleansing composition of claim 1, wherein the composition further comprises sodium chloride in an amount of 0.1 to 1.2 weight % of the composition.

18. The cleansing composition of claim 1, wherein the thickener is present in an amount of 0.1 to 1 weight % of the composition.

19. The cleansing composition of claim 1, wherein the thickener is PEG-120 methyl glucose dioleate present in an amount of 0.1 to 1 weight % of the composition, and wherein the cetyltrimethylammonium chloride is present in an amount of 1 to 5 weight % of the composition, and wherein the nonionic surfactant comprises a mixture of laurylamidopropyl dimethylamine oxide, myristylamidopropyl dimethylamine oxide, and cocomonoethanolamide, and wherein the nonionic surfactant is present in an amount of 0.5 to 5 weight % of the composition.

20. The cleansing composition of claim 19, further comprising the cationic antibacterial agent benzalkonium chloride.

21. The cleansing composition of claim 19, wherein the composition further comprises sodium chloride in an amount of 0.1 to 1.2 weight % of the composition.

22. The cleansing composition of claim 19, wherein the composition does not contain an anionic surfactant.