Exhibit 10.3


 





ANCHIANO THERAPEUTICS LTD./
CHEMOMAB LTD. 


REGISTRATION RIGHTS AGREEMENT


 


This REGISTRATION RIGHTS
AGREEMENT (this “Agreement”) is made and entered into as of this 14 day of December 2020, with effectiveness as
of the Effective Date (as defined below), by and among (i) Anchiano Therapeutics Ltd., an Israeli company, which will change its name
to Chemomab Therapeutics Ltd. upon the Effective Date (the “Company”), (ii) each person or entity listed on Schedule
A hereto (the “Shareholders”) who will hold, as of the Effective Date, the Company’s ordinary shares,
no par value each (“Ordinary Shares“), in the form of American Depositary Shares (each, an “ADS”),
which represent Ordinary Shares at a ratio of one (1) ADS per five (5) Ordinary Shares, and (iii) Adi Mor and Kobi George (the “Founders”).


 


RECITALS


 


WHEREAS,
concurrently herewith, the Company and CMB Acquisition Ltd., an Israeli limited company and wholly owned subsidiary of the Company
(“Merger Sub”), are entering into an Agreement and Plan of Merger (the “Merger Agreement”),
dated of even date herewith, with Chemomab Ltd., an Israeli limited company (the “Target Company”) whereunder
Merger Sub will merge with and into the Target Company (the “Merger”) in accordance with the Merger Agreement and
in accordance with the provisions of Sections 314-327 of the Israeli Companies Law, 5759-1999 (the “Companies
Law”), and, on the effective date thereof (the “Effective Date”), Merger Sub will cease to exist and
the Target Company will become a wholly owned subsidiary of the Company, on the terms and subject to the conditions set forth in the
Merger Agreement;


 


WHEREAS, pursuant to
the Merger Agreement, on the Effective Date, each share of Target Company issued and outstanding immediately prior to the Effective Date
(excluding shares to be canceled pursuant to Section ‎1.5(a)(i) of the Merger Agreement), including shares held by the
Shareholders, shall be automatically converted solely into the right to receive a number of Company ADSs equal to the exchange ratio under
the Merger Agreement;


 


WHEREAS, the offer
and issuance of the Ordinary Shares (in the form of ADSs) to the Shareholders pursuant to the Merger Agreement has not been, and will
not be, registered under the Securities Act (as defined below), and the Shareholders’ Ordinary Shares (in the form of ADSs) will
therefore be “restricted securities” as defined by SEC Rule 144 (as defined below), and the parties to the Merger Agreement
have agreed to provide the Shareholders with certain registration rights pursuant to this Agreement to enable them to sell their Ordinary
Shares (in the form of ADSs) publicly once the lock-up period following the Merger under the Lock-Up Agreement (as defined below) expires,
in a transaction registered under ** the Securities Act and the rules and regulations promulgated thereunder;


 


WHEREAS, as part of
the entry into, and effectiveness of, this Agreement, the shareholders of the Target Company party hereto, who together constitute the
requisite “Majority Investors” under that certain Amended and Restated Investor Rights’ Agreement, dated as of September
23, 2019, by and among the Target Company, certain holders of the Target Company’s Series C Preferred Shares, an additional investor
in the Target Company and a founder of the Target Company (the “Existing Registration Rights Agreement”), are terminating
their registration rights under the Existing Registration Rights Agreement, as provided in Section 7.14 hereof (other than the rights
under Section 2.11 of the Existing Registration Rights Agreement, which are incorporated into this Agreement in Section 5 hereof); and


 


WHEREAS, the Founders
are being granted certain registration rights under this Agreement in order to enable the sale of the Ordinary Shares held by them from
time to time in one or more transactions registered under the Securities Act.


 






     

     


    

 


NOW, THEREFORE, contingent
upon and as of the consummation of the Merger, the parties agree as follows:


 


	1.	Definitions. For purposes of this Agreement:



 


1.1.       
“ADS” has the meaning set forth in the preamble.


 


1.2.       
“Agreement” shall have the meaning set forth in the preamble.


 


1.3.       
“Affiliate” means, with respect to any specified Person, any other Person who or which, directly or indirectly,
controls, is controlled by or is under common control with such Person, including, without limitation, any general partner, managing member,
officer, director, or manager of such Person and any venture capital fund now or hereafter existing that is controlled by one or more
general partners of, or shares the same management company with, such Person.


 


 


1.4.       
“Company” shall have the meaning set forth in the preamble.


 


1.5.       
“Damages” means any loss, damage, fees (including attorneys’ fees), costs or liability (joint or several)
to which a party hereto may become subject under the Securities Act, the Exchange Act, or other applicable law, insofar as such loss,
damage, or liability (or any action in respect thereof) arises out of or is based upon (i) any untrue statement or alleged untrue statement
of a material fact contained in any registration statement of the Company, including any preliminary prospectus or final prospectus contained
therein or any amendments or supplements thereto, or any prospectus supplement thereto, and including any documents or other information
incorporated by reference in any such registration statement; (ii) an omission or alleged omission to state therein a material fact required
to be stated therein, or necessary to make the statements therein, in light of the circumstance in which they are made, not misleading;
or (iii) any violation or alleged violation by the indemnifying party (or any of its agents or Affiliates) of the Securities Act, the
Exchange Act, any state securities law, or any rule or regulation promulgated under the Securities Act, the Exchange Act, or any state
securities law.


 


1.6.       
“Demand Notice” shall have the meaning set forth in Section 2.1.1


 


 


1.7.       
“Effective Date” shall have the meaning set forth in the Recitals.


 


 


1.8.       
“Exchange Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated
thereunder.


 


1.9.       
“Form S-1” means such form (or any comparable successor form or similar
form available for foreign private issuers, such as Form F-1, if available) under the Securities Act as in effect on the date hereof
or any successor registration form under the Securities Act subsequently adopted by the SEC.


 


1.10.    
“Form S-3” means such form (or any comparable successor form or similar form available to foreign private issuers,
such as Form F-3, if available) under the Securities Act as in effect on the date hereof or any registration form under the Securities
Act subsequently adopted by the SEC that permits both historical and forward incorporation of substantial information by reference to
other documents filed by the Company with the SEC.


 


1.11.    
 “Founders” shall have the meaning set forth in the preamble.


 


1.12.    
“Holder” means any holder of Registrable Securities who is a party to this Agreement.


 


1.13.    
“Initiating Holders” shall have the meaning set forth in Section 2.1.1.


 


1.14.    
“Included Registrable Securities” shall have the meaning set forth in Section 2.2.1.


 


1.15.    
“Lock-Up Agreement” means the lock-up agreement entered into by each Shareholder with the Company pursuant to
the Merger Agreement.


 


1.16.    
“Merger” shall have the meaning set forth in the Recitals.


 






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1.17. “Merger
Agreement” shall have the meaning set forth in the Recitals.


 


1.18.    
“Ordinary Shares” shall have the meaning set forth in the preamble.


 


1.19.    
“Permitted Transferee” means: (i) in the case of an individual Shareholder - a spouse, parents, child, brother,
sister or trustee of the shareholder (or his/her spouse) and any corporation, limited liability company, limited partnership, or other
entity or trust which is controlled by him/her; (ii) in the case of any incorporated or limited liability company Shareholder - an entity
that controls, is controlled by, or is under common control with such incorporated shareholders; and (iii) in case of any Shareholder
which is a limited or general partnership - its partners, affiliated partnerships managed by the same management company or managing (general)
partner or by an entity which controls, is controlled by, or is under common control with, such management company or managing (general)
partner.


 


1.20.    
“Person” means any individual, corporation, partnership, association, limited liability company, trust or any
other entity.


 


1.21.    
“Piggy-Back Underwritten Offering” shall have the meaning set forth in Section 2.2.1.


 


1.22.    
“Registrable Securities” means the Shares held by any Shareholder or by the Founders, which status as Registrable
Securities shall terminate once such Shares (i) are sold by a Holder to the public either pursuant to a registration statement or SEC
Rule 144; (ii) are sold by a Holder in a transaction in which the rights under Section 2 hereof are not assigned; or (iii) (except for
the Founders’ Shares) can be sold without limitation under SEC Rule 144 or another similar exemption under the Securities Act, during
a ninety (90) day period without registration.


 


1.23.    
“SEC” means the U.S. Securities and Exchange Commission.


 


1.24.    
 “SEC Rule 144” means Rule 144 promulgated by the SEC under the Securities Act.


 


1.25.    
“SEC Rule 145” means Rule 145 promulgated by the SEC under the Securities Act.


 


1.26.    
“Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.


 


1.27.    
“Selling Expenses” shall have the meaning set forth in Section 3.3.


 


1.28.    
“Selling Holder Counsel” shall have the meaning set forth in Section 3.3.


 


1.29.    
“Shares” means and includes Ordinary Shares (including Ordinary Shares represented by ADSs) issued and outstanding
from time to time, now owned or subsequently acquired by a Shareholder, however acquired, whether through share splits, share dividends,
reclassifications, recapitalizations, similar events or otherwise.


 


1.30.    
“Shareholders” shall have the meaning set forth in the preamble.


 


1.31.    
“Shelf Registration Statement” shall have the meaning set forth in Section 2.1.1.


 


1.32.    
“Undesignated Registrable Securities” shall have the meaning set forth in Section 2.2.2.


 


1.33.    
“WKSI” shall have the meaning set forth in the Section 2.2.1.


 






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		2.	Registration Rights. The Company covenants and agrees as follows:



 


2.1.       
Demand Registration


 


2.1.1.           
 If at any time after the Effective Date, but subject to the restriction on the sale of Ordinary Shares (including in the
form of ADSs) by the Shareholders during the 180 day period following the Effective Date under the Lock-Up Agreement entered into by each
Shareholder (unless the restrictions thereunder are waived by the Company, subject to such a waiver being applied equally to all Shareholders),
the Company receives a request from Holders of at least 30% of the Registrable Securities then outstanding, or from either of the Founders,
that the Company file a registration statement, or a prospectus supplement to an effective
registration statement with respect to an offering to be made on a delayed or continuous basis pursuant to Rule 415 promulgated under
the Securities Act (a “Shelf Registration Statement”), with respect to the resale of outstanding Registrable Securities
of such Holders having an anticipated aggregate offering price, net of Selling Expenses (as defined below), of at least $5 million, or
in the case of a request from one or both of the Founders, with an anticipated offering price, after including additional
Registrable Securities requested to be included in such registration by any other Holders, as described below, net of Selling Expenses,
of at least $1 million (in either such case, the Holder(s) (including, if applicable, the Founders) making the request are referred to
as the “Initiating Holder(s)”), then the Company shall: (i) within ten (10) business days after the date such request
is given, give notice thereof (the “Demand Notice”) to all Holders other than the Initiating Holder(s); and (ii) as
soon as practicable, and in any event within ninety (90) days after the date such request is given by the Initiating Holder(s), file a
Form S-1 (or any comparable successor form or similar form available for foreign issuers, such
as Form F-1, if available), or, if the Company is then eligible, a Form S-3 (or any comparable successor form or similar form available
to foreign issuers, such as Form F-3, if available) registration statement, or a prospectus supplement to an already effective Shelf Registration
Statement on Form S-3 or Form F-3, covering all Registrable Securities that the Initiating
Holder(s) requested to be registered and any
additional Registrable Securities requested to be included in such registration by any other Holders, as specified by notice given by
each such Holder to the Company within twenty (20) days of the date the Demand Notice is given, and in each case, subject to the
limitations of Section 2.1.2 and Section 2.3; provided, however, that the Company
shall not file any registration statement or prospectus supplement pursuant to this Section 2.1.1 prior to the expiration of 90 days following
the Effective Date.


 


2.1.2.           
Notwithstanding the foregoing obligations, if the Company furnishes to Holders requesting a registration pursuant to this Section
2.1 a certificate signed by the Company’s chief executive officer (or, in the case of a registration demand that includes Registrable
Securities held by the Founders, signed by the chairman of the Company’s board of directors) stating that in the good faith judgment
of the Company’s board of directors it would be materially detrimental to the Company and its shareholders for such registration
statement to either become effective or remain effective for as long as such registration statement otherwise would be required to remain
effective because such action would (i) materially interfere with a significant acquisition, corporate reorganization, or other similar
transaction involving the Company; (ii) require premature disclosure of material information that the Company has a bona fide business
purpose for preserving as confidential; or (iii) render the Company unable to comply with requirements under the applicable securities
laws, then the Company shall have the right to defer taking action with respect to such filing, and any time periods with respect to filing
or (to the extent applicable) effectiveness thereof shall be tolled correspondingly, for a period of not more than ninety (90) days after
the request of the Initiating Holders is given; provided, however, that the Company may not invoke this right more than once in any twelve
(12) month period; and provided further, that the Company shall not register any securities for its own account (except pursuant to Section
2.2) or of any other shareholder during such ninety (90)-day period, other than pursuant to a registration relating to the sale of securities
to employees of the Company or a subsidiary pursuant to a share option, share purchase, or similar plan; a registration on any form that
does not include substantially the same information as would be required to be included in a registration statement covering the sale
of the Registrable Securities; or a registration in which the only Ordinary Shares (including Ordinary Shares represented by ADSs) being
registered are Ordinary Shares (including Ordinary Shares represented by ADSs) issuable upon conversion of debt securities that are also
being registered.


 






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2.1.3.            The
Company shall not be obligated to effect but shall take action to facilitate effecting (including sending a Demand Notice to all
Holders other than the Initiating Holder(s)), any registration pursuant to Section 2.1.1: (i) during the period that is thirty (30)
days before the Company’s good faith estimate of the date of filing of, and ending on a date that is ninety (90) days after
the effective date of, a Company-initiated registration; provided, that the Company is actively employing in good faith commercially
reasonable efforts to cause such Company-initiated registration statement to become effective; (ii) after the Company has effected
three (3) registrations pursuant to Section 2.1.1; or (iii) if the Company has effected two registrations pursuant to Section 2.1.1
within the twelve (12) month period immediately preceding the date of such request or has effected a registration pursuant to
Section 2.1.1 within the ninety (90) day period immediately preceding the date of such request. A registration shall not be counted
as “effected” for purposes of this Section 2.1.3 until such time as the applicable registration statement has been
declared effective by the SEC, unless the Initiating Holders withdraw their request for such registration (unless they elect to pay
the registration expenses therefor) and therefore forfeit their right to one demand registration statement pursuant to Section
2.1.1, in which case such withdrawn registration statement shall be counted as “effected” for purposes of this
Section 2.1.3; provided, that, a registration shall not be counted as “effected” if the Initiating Holders
withdraw their request following the Company’s exercise of its delay rights contained in Section 2.1.2.


 


2.1.4.           
Notwithstanding the registration obligations set forth in this Section 2.1,
if the SEC informs the Company that the full number of Registrable Securities cannot, as a result of the application of Rule 415 under
the Securities Act, be registered for resale as a secondary offering on a single registration statement on Form S-3 or Form F-3,
then the Company agrees to promptly inform each of the Holders who requested inclusion of their Registrable Securities in the subject
registration statement and use its commercially reasonable efforts to file amendments to the subject registration statement as required
by the SEC, to cover the maximum number of Registrable Securities permitted to be included by the SEC; provided, however,
that prior to filing such amendment, the Company shall be obligated to use diligent efforts to advocate with the SEC for the registration
of all of the Registrable Securities in accordance with relevant SEC guidance, including without limitation, SEC Compliance and Disclosure
Interpretation 612.09.  Notwithstanding any other provision of this Agreement, if the SEC or any guidance of the staff of the SEC
sets forth a limitation on the number of Registrable Securities permitted to be registered on the subject registration statement as a
secondary offering (and notwithstanding that the Company used diligent efforts to advocate with the SEC for the registration of all or
a greater portion of Registrable Securities), unless otherwise directed in writing by a Holder as to its Registrable Securities, the number
of Registrable Securities to be registered on the subject registration statement shall be allocated as follows (the number of Registrable
Securities not registered, the “Cutback Shares”): (i) first, only to the extent that the subject registration
statement is filed prior to the expiration of 24 months following the Effective Date, to the Founders (to the extent the Founders
have requested to include Registrable Securities in the subject demand offering), and (ii) second, among all other such Holders of Registrable
Securities, including the Initiating Holders (and including, if the subject registration statement is filed following the expiration of
24 months after the Effective Date, the Founders) in proportion (as nearly as practicable) to the number of Registrable Securities owned
by each such Holder, or in such other proportion as shall mutually be agreed to by all such Holders.  In the event of a cutback hereunder,
the Company shall give each Holder who requested inclusion of its Registrable Securities
at least seven (7) days prior written notice along with the calculations as to such Holder’s allotment.  In the event the Company
amends the subject registration statement in accordance with the foregoing, the Company will use its commercially reasonable efforts to
file with the SEC, as promptly as allowed by the SEC or guidance of the staff thereof provided to the Company or to registrants of securities
in general, one or more registration statements on Form S-1, Form F-1, Form S-3 or Form F-3 (subject to the Company’s eligibility)
to register for resale those Registrable Securities that were not registered for resale on the initial/subject registration statement,
as amended (any such other registration statements, an “Additional Registration Statement”)..


 






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2.2.       
Company Registration.


 


2.2.1.            If
at any time following the Effective Date the Company, including if the Company qualifies as a well-known seasoned issuer (within the
meaning of Rule 405 under the Securities Act) (a “WKSI”), proposes to file (i) a prospectus supplement to an
effective Shelf Registration Statement, or (ii) a registration statement, other than a Shelf Registration Statement for a delayed or
continuous offering pursuant to Rule 415 under the Securities Act, in either case, for the sale of Ordinary Shares (including
Ordinary Shares represented by ADSs) for its own account, or for the benefit of the holders of any of its securities other than the
Holders, to an underwriter on a firm commitment basis for reoffering to the public or in a “bought deal” or
“registered direct offering” with one or more investment banks (collectively, a “Piggy-Back Underwritten
Offering”) then as soon as practicable but not less than ten (10) days prior to the filing of (a) any preliminary
prospectus supplement relating to such Piggy-Back Underwritten Offering pursuant to Rule 424(b) under the Securities Act, (b) any
prospectus supplement relating to such Piggy-Back Underwritten Offering pursuant to Rule 424(b) under the Securities Act (if no
preliminary prospectus supplement is used) or (c) such Shelf Registration Statement, as the case may be, the Company shall give
notice of such proposed Piggy-Back Underwritten Offering to the Holders and such notice shall offer the Holders the opportunity to
include in such Piggy-Back Underwritten Offering such number of Registrable Securities (the “Included Registrable
Securities”) as each such Holder may request in writing. Prior to the commencement of any “road show,” any
Holder shall have the right to withdraw its request for inclusion of its Registrable Securities in any Registration by giving
written notice to the Company of its request to withdraw, and such withdrawal shall be irrevocable and, after making such
withdrawal, such Holder shall no longer have any right to include Registrable Securities in the Piggy-Back Underwritten Offering as
to which such withdrawal was made. The notice required to be provided to Holders shall be provided on a business day. Each such
Holder shall then have seven (7) days after receiving such notice to request in writing to the Company inclusion of Registrable
Securities in the Piggy-Back Underwritten Offering, except that such Holder shall have two (2) business days after such Holder
confirms receipt of the notice to request inclusion of Registrable Securities in the Piggy Back Underwritten Offering in the case of
a “bought deal”, “registered direct offering” or “overnight transaction” where no preliminary
prospectus is used. Upon receipt of any such request for inclusion from a Holder received within the specified time, the Company
shall use commercially reasonable efforts to effect the registration in any registration statement of any of the Holders’
Registrable Securities requested to be included on the terms set forth in this Agreement. If no request for inclusion from a Holder
is received within the specified time, such Holder shall have no further right to participate in such Piggy-Back Underwritten
Offering. For the avoidance of doubt, registration by the Company of options or shares of employees or consultants, and registration
of securities in an SEC Rule 145 transaction, shall not be deemed to constitute a Piggy-Back Underwritten Offering.


 


2.2.2.           
Unless the Company qualifies as a WKSI, (i) the Company shall give each Holder ten (10) days’ notice prior to filing a Shelf
Registration Statement and, upon the written request of any Holder, received by the Company within seven (7) days of such notice to the
Holder, the Company shall include in such Shelf Registration Statement a number of Ordinary Shares (including Ordinary Shares represented
by ADSs) equal to the aggregate number of Registrable Securities requested to be included without naming any requesting Holder as a selling
shareholder and including only a generic description of the holder of such securities (the “Undesignated Registrable Securities”),
(ii) the Company shall not be required to give notice to any Holder in connection with a filing pursuant to Section 2.2.1 unless such
Holder provided such notice to the Company pursuant to this Section 2.2.2 and included Undesignated Registrable Securities in the Shelf
Registration Statement related to such filing, and (iii) at the written request of a Holder given to the Company more than seven (7) days
before the date specified in writing by the Company as the Company’s good faith estimate of a launch of a Piggy-Back Underwritten
Offering (or such shorter period to which the Company in its sole discretion consents), the Company shall use commercially reasonable
efforts to effect the registration of any of the Holders’ Undesignated Registrable Securities so requested to be included and shall
file a post-effective amendment or, if available, a prospectus supplement to a Shelf Registration Statement to include such Undesignated
Registrable Securities as any Holder may request, provided that (a) the Company is actively employing commercially reasonable efforts
to effect such Piggy-Back Underwritten Offering; and (b) the Company shall not be required to effect a post-effective amendment more than
two (2) times in any twelve (12)-month period.


 


2.2.3.           
The Company shall have the right to terminate or withdraw any registration initiated by it under this Section 2.2 before the effective
date of such registration, whether or not any Holder has elected to include Registrable Securities in such registration. The expenses
(other than Selling Expenses) of such withdrawn registration shall be borne by the Company in accordance with Section 3.3.


 






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2.3.       
Underwriting Requirements


 


2.3.1.            If,
pursuant to Section 2.1, the Initiating Holder(s) intend to distribute the Registrable Securities covered by their request by means
of an underwriting, they shall so advise the Company as a part of their request made pursuant to Section 2.1, and the Company shall
include such information in the Demand Notice. The underwriter(s) will be selected by the Initiating Holders holding a majority of
the Registrable Securities held by the applicable Initiating Holders, subject to the reasonable approval of the Company. In such
event, the right of any Holder to include such Holder’s Registrable Securities in such registration shall be conditioned upon
such Holder’s participation in such underwriting and the inclusion of such Holder’s Registrable Securities in the
underwriting to the extent provided herein. All Holders proposing to distribute their securities through such underwriting shall
(together with the Company as provided in Section 3.1.6) enter into an underwriting agreement in customary form with the
underwriter(s) selected for such underwriting. Notwithstanding any other provision of this Section 2.3, if the underwriter(s)
advise(s) the Initiating Holders in writing that marketing factors require a limitation on the number of shares to be underwritten,
then the Initiating Holders shall so advise all Holders of Registrable Securities that otherwise would be underwritten pursuant
hereto, and the number of Registrable Securities that may be included in the underwriting shall be allocated, (i) first, only to the
extent that the registration statement related to the underwriting was filed prior to
the expiration of 24 months following the Effective Date, to the Founders (to the extent the Founders have requested to include
Registrable Securities in the subject demand offering), and (ii) second, among all other such Holders of Registrable Securities,
including the Initiating Holders (and including, if the subject registration statement is filed following the expiration of 24
months after the Effective Date, the Founders), in proportion (as nearly as practicable) to the number of Registrable Securities
owned by each Holder or in such other proportion as shall mutually be agreed to by all such selling Holders; provided, however, that
the number of Registrable Securities held by the Founders and other Holders to be included in such underwriting shall not be reduced
unless all other securities are first entirely excluded from the underwriting.


 


2.3.2.           
In connection with any offering involving an underwriting of shares of the Company’s share capital pursuant to Section 2.2,
the Company shall not be required to include any of the Holders’ (including the Founders’) Registrable Securities in such
underwriting unless the relevant Holders accept the terms of the underwriting as agreed upon between the Company and its underwriters,
and then only in such quantity as the underwriters in their sole discretion determine will not jeopardize the success of the offering
by the Company. If the total number of Registrable Securities requested by Holders to be included in such offering exceeds the number
of securities to be sold (other than by the Company) that the underwriters in their reasonable discretion determine is compatible with
the success of the offering, then the Company shall be required to include in the offering only that number of such Registrable Securities
which the underwriters in their sole discretion determine will not jeopardize the success of the offering. If the underwriters determine
that less than all of the Registrable Securities requested to be registered can be included in such offering, then the Registrable Securities
that are included in such offering shall be allocated (a) first, only to the extent that the registration
statement related to the offering was filed prior to the expiration of 24 months following the Effective Date, to the Founders,
and (b) second, among the selling Holders (including, if the subject registration statement is filed following the expiration of 24 months
after the Effective Date, the Founders), in proportion (as nearly as practicable to) the number of Registrable Securities owned by each
selling Holder or in such other proportions as shall mutually be agreed to by all such selling Holders. Notwithstanding the foregoing,
in no event shall (i) the number of Registrable Securities included in the offering be reduced unless all other securities (other than
securities to be sold by the Company) are first entirely excluded from the offering.


 


2.3.3.           
For purposes of Section 2.1, a registration shall not be counted as “effected”
if, as a result of an exercise of the underwriter’s cutback provisions in Section 2.3.1, fewer than fifty percent (50%) of the total
number of Registrable Securities that Holders have requested to be included in such registration statement are actually included. In addition,
in the event of a cutback described in Section 2.1.4, a registration shall not be counted as “effected” for purposes of Section
2.1 until all Cutback Shares are registered under an Additional Registration Statement
related to the subject registration demand.


 


2.4.       
Delay of Registration. No Holder shall have any right to obtain or seek an injunction restraining or otherwise delaying
any registration pursuant to this Agreement as the result of any controversy that might arise with respect to the interpretation or implementation
of Section 2 and Section 3.3 hereof.


 


2.5.       
Reports Under Exchange Act. With a view to making available to the Holders the benefits of SEC Rule 144 and any other rule
or regulation of the SEC that may at any time permit a Holder to sell securities of the Company to the public without registration or
pursuant to a registration on Form S-3 (or any comparable successor form or similar form available to foreign issuers, such as Form F-3,
if available), the Company shall, provided that the Company’s securities are registered under the Exchange Act:


 


2.5.1.           
make and keep available adequate current public information, as those terms are understood and defined in SEC Rule 144, at all
times after the Effective Date;


 






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2.5.2.           
 use commercially reasonable efforts to file with the SEC in a timely manner all reports and other documents required of the Company
under the Securities Act and the Exchange Act (at any time after the Company has become subject to such reporting requirements); and


 


2.5.3.           
furnish to any Holder, so long as the Holder owns any Registrable Securities, forthwith upon request (i) to the extent accurate,
a written statement by the Company that it has complied with the reporting requirements of (at any time following the lock-up period under
the Lock-Up Agreement) the Securities Act, and the Exchange Act (assuming that the Company is then still subject to such reporting requirements),
or that it qualifies as a registrant whose securities may be resold pursuant to Form S-3 (or any comparable successor form or similar
form available to foreign issuers, such as Form F-3, if available) (at any time after the Company so qualifies); (ii) a copy of the most
recent annual or quarterly report of the Company and such other reports and documents so filed by the Company; and (iii) such other information
as may be reasonably requested in availing any Holder of any rule or regulation of the SEC that permits the selling of any such securities
without registration (at any time after the Company has become subject to the reporting requirements under the Exchange Act) or pursuant
to Form S-3 (or any comparable successor form or similar form available to foreign issuers, such as Form F-3, if available) (at any time
after the Company so qualifies to use such form); provided, that, no such information need be provided if such information is publicly
available on EDGAR.


 


 2.6.        Restriction on Transfer




 


2.6.1.           
The Registrable Securities shall not be sold, pledged, or otherwise transferred, and the Company shall not recognize and shall
issue stop-transfer instructions to its transfer agent with respect to any such sale, pledge, or transfer, except (i) upon the conditions
specified in this Agreement, which conditions are intended to ensure compliance with the provisions of the Securities Act, or (ii) in
accordance with any exemption from registration under the Securities Act, including SEC Rule 144. A transferring Holder will cause any
proposed purchaser, pledgee, or transferee of the Registrable Securities held by such Holder to agree to take and hold such securities
subject to the provisions and upon the conditions specified in this Agreement.


 


2.6.2.           
Each certificate or instrument representing the Registrable Securities, and any other securities issued in respect of the Registrable
Securities, upon any share split, share dividend, recapitalization, merger, consolidation, or similar event, shall (unless otherwise permitted
by the provisions of Section 2.6.3) be stamped or otherwise imprinted with a legend substantially in the following form:


 


THE SECURITIES REPRESENTED HEREBY
HAVE BEEN ACQUIRED FOR INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE U.S. SECURITIES ACT OF 1933, AS AMENDED. SUCH SHARES MAY NOT
BE SOLD, PLEDGED, OR TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION OR A VALID EXEMPTION FROM THE REGISTRATION AND PROSPECTUS DELIVERY
REQUIREMENTS OF SAID ACT.


 


The Holders consent
to the Company making a notation in its records and giving instructions to any transfer agent of the Registrable Securities in order to
implement the restrictions on transfer set forth in this Section 2.6.


 


2.6.3.            The
holder of each certificate representing Registrable Securities , by acceptance thereof, agrees to comply in all respects with the
provisions of this Section 2. Before any proposed sale, pledge, or transfer of any Registrable Securities, unless there is in
effect a registration statement under the Securities Act covering the proposed transaction, the Holder thereof shall provide to the
Company and/or its transfer agent any of (i) a written opinion of legal counsel who shall, and whose legal opinion shall, be
reasonably satisfactory to the Company, addressed to the Company and/or its transfer agent, to the effect that the proposed
transaction may be effected without registration under the Securities Act; (ii) a “no action” letter from the SEC
to the effect that the proposed sale, pledge, or transfer of such Registrable Securities without registration will not result in a
recommendation by the staff of the SEC that action be taken with respect thereto; or (iii) any other evidence reasonably
satisfactory to counsel to the Company to the effect that the proposed sale, pledge, or transfer of the Registrable Securities may
be effected without registration under the Securities Act, whereupon the Holder of such Shares shall be entitled to sell, pledge, or
transfer such Registrable Securities . Each certificate or instrument evidencing the Registrable Securities transferred as above
provided shall bear, except if such transfer is made pursuant to SEC Rule 144, the appropriate restrictive legend set forth in
Section 2.6.2, except that such certificate shall not bear such restrictive legend if, in the opinion of counsel for such
Holder and the Company, such legend is not required in order to establish compliance with any provisions of the Securities Act.


 






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2.7.       
Indemnification. If any Registrable Securities are included in a registration statement under Section 2 hereof:


 


2.7.1.           
To the extent permitted by law, the Company will indemnify and hold harmless each selling Holder, and the partners, members, officers,
directors, and shareholders of each such Holder; any underwriter (as defined in the Securities Act) for each such Holder; and each Person,
if any, who controls such Holder or underwriter within the meaning of the Securities Act or the Exchange Act, against any Damages, and
the Company will pay to each such Holder, underwriter, controlling Person, or other aforementioned Person any legal or other expenses
reasonably incurred thereby in connection with investigating or defending any claim or proceeding from which Damages may result, as such
expenses are incurred; provided, however, that the indemnity agreement contained in this Section 2.7.1 shall not apply to amounts paid
in settlement of any such claim or proceeding if such settlement is effected without the consent of the Company (which consent shall not
be unreasonably withheld, conditioned or delayed), nor shall the Company be liable for any Damages to the extent that they arise out of
or are based upon actions or omissions made in reliance upon and in conformity with written information furnished by or on behalf of any
such Holder, underwriter, controlling Person, or other aforementioned Person expressly for use in connection with such registration.


 


2.7.2.           
To the extent permitted by law, each selling Holder, severally and not jointly, will indemnify and hold harmless the Company, and
each of its directors, each of its officers who has signed the registration statement, each Person (if any), who controls the Company
within the meaning of the Securities Act, legal counsel and accountants for the Company, any underwriter (as defined in the Securities
Act), any other Holder selling securities in such registration statement, and any controlling Person of any such underwriter or other
Holder, against any Damages, in each case only to the extent that such Damages arise out of or are based upon actions or omissions made
in reliance upon and in conformity with written information furnished by or on behalf of such selling Holder expressly for use in connection
with such registration; and each such selling Holder will pay to the Company and each other aforementioned Person any legal or other expenses
reasonably incurred thereby in connection with investigating or defending any claim or proceeding from which Damages may result from such
written information, as such expenses are incurred; provided, however, that the indemnity agreement contained in this Section 2.7.2 shall
not apply to amounts paid in settlement of any such claim or proceeding if such settlement is effected without the consent of the Holder;
and provided further that in no event shall any indemnity under this Section 2.7.2 exceed the proceeds from the offering received by such
Holder (net of any Selling Expenses paid by such Holder), except in the case of fraud or willful misconduct by such Holder.


 


2.7.3.            Promptly
after receipt by an indemnified party under this Section 2.7 of notice of the commencement of any action (including any governmental
action) for which a party may be entitled to indemnification hereunder, such indemnified party will, if a claim in respect thereof
is to be made against any indemnifying party under this Section 2.7, give the indemnifying party notice of the commencement thereof.
The indemnifying party shall have the right to participate in such action and, to the extent the indemnifying party so desires,
participate jointly with any other indemnifying party to which notice has been given, and to assume the defense thereof with counsel
retained by the indemnifying party who shall be reasonably satisfactory to the indemnified party; provided, however, that an
indemnified party (together with all other indemnified parties that may be represented without conflict by one counsel) shall have
the right to retain one separate counsel, with the fees and expenses to be paid by the indemnifying party, if representation of such
indemnified party by the counsel retained by the indemnifying party would be inappropriate due to actual or potential differing
interests between such indemnified party and any other party represented by such counsel in such action. The failure to give notice
to the indemnifying party within a reasonable time of the commencement of any such action shall relieve such indemnifying party of
any liability to the indemnified party under this Section 2.7, to the extent that such failure materially prejudices the
indemnifying party’s ability to defend such action. The failure to give notice to the indemnifying party will not relieve it
of any liability that it may have to any indemnified party otherwise than under this Section 2.7.


 






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2.7.4.           
To provide for just and equitable contribution to joint liability under the Securities Act in any case in which either (i) any
party otherwise entitled to indemnification hereunder makes a claim for indemnification pursuant to this Section 2.7 but it is judicially
determined (by the entry of a final judgment or decree by a court of competent jurisdiction and the expiration of time to appeal or the
denial of the last right of appeal) that such indemnification may not be enforced in such case, notwithstanding the fact that this Section
2.7 provides for indemnification in such case, or (ii) contribution under the Securities Act may be required on the part of any party
hereto for which indemnification is provided under this Section 2.7, then, and in each such case, such parties will contribute to the
aggregate losses, claims, damages, liabilities, or expenses to which they may be subject (after contribution from others) in such proportion
as is appropriate to reflect the relative fault of each of the indemnifying party and the indemnified party in connection with the statements,
omissions, or other actions that resulted in such loss, claim, damage, liability, or expense, as well as to reflect any other relevant
equitable considerations. The relative fault of the indemnifying party and of the indemnified party shall be determined by reference to,
among other things, whether the untrue or allegedly untrue statement of a material fact, or the omission or alleged omission of a material
fact, relates to information supplied by the indemnifying party or by the indemnified party and the parties’ relative intent, knowledge,
access to information, and opportunity to correct or prevent such statement or omission; provided, however, that, in any such case, (x)
no Holder will be required to contribute any amount in excess of the public offering price of all such Registrable Securities offered
and sold by such Holder pursuant to such registration statement, and (y) no Person guilty of fraudulent misrepresentation (within the
meaning of Section 11(f) of the Securities Act) will be entitled to contribution from any Person who was not guilty of such fraudulent
misrepresentation; and provided further that in no event shall a Holder’s liability pursuant to this Section 2.7.4, when combined
with the amounts paid or payable by such Holder pursuant to Section 2.7.2, exceed the proceeds from the offering received by such Holder
(net of any Selling Expenses) paid by such Holder), except in the case of willful misconduct or fraud by such Holder.


 


2.7.5.           
The obligations of the Company and Holders under this Section 2.7 shall survive the completion of any offering of Registrable Securities
in a registration under Section 2 hereof, and otherwise shall survive the termination of this Agreement.


 


	3.	Covenants of the Company



 


3.1.       
The Company agrees to use commercially reasonable efforts, within the requirements of applicable law, to ensure that the rights
granted under this Agreement are effective and that the parties enjoy the benefits of this Agreement. Such actions include, without limitation,
whenever required under this Agreement to effect a registration (including an Additional Registration Statement filed pursuant to Section
2.1.4), the use of the Company’s commercially reasonable efforts to, as expeditiously as reasonably possible and subject to the
requirements under the applicable securities laws:


 


3.1.1.           
prepare and file a registration statement with respect to the Registrable Securities and use its commercially reasonable efforts
to cause such registration statement to become effective and, upon the request of the Initiating Holders, keep such registration statement
effective for a period of up to one hundred eighty (180) days, or in the case of registration on a Shelf Registration Statement on Form
S-3 or Form F-3, for a minimum of two (2) years, or, in either case, if earlier, until the distribution contemplated in the registration
statement has been completed; provided, however, that such one hundred eighty (180) day or two (2) year period shall be extended for a
period of time equal to the period the Holder refrains, at the request of an underwriter, from selling any Registrable Securities included
in such registration;


 


3.1.2.           
prepare and file such amendments and supplements to such registration statement, and the prospectus used in connection with such
registration statement, as may be necessary to comply with the applicable securities laws in order to enable the disposition of all Registrable
Securities covered by such registration statement;


 






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3.1.3.           
 furnish to the selling Holders such numbers of copies of a prospectus, including a preliminary prospectus, as required by the
applicable securities laws, and such documents as the selling Holders may reasonably request in order to facilitate their disposition
of their Registrable Securities;


 


3.1.4.           
use its commercially reasonable efforts to register and qualify the Registrable Securities covered by such registration statement
under such other securities laws of such jurisdictions as shall be reasonably requested by the selling Holders;


 


3.1.5.           
Notwithstanding Section 3.1.4 hereof and anything to the contrary in this Agreement, the Company shall register shares under this
Agreement in a certain jurisdiction only provided the Company shall not be required to qualify to do business or to file a general consent
to service of process in any such states or jurisdictions, unless the Company is already subject to service in such jurisdiction and except
as may be required by applicable securities laws;


 


3.1.6.           
in the event of any underwritten public offering, enter into and perform its obligations under an underwriting agreement, in usual
and customary form, with the underwriter(s) of such offering;


 


3.1.7.           
use its commercially reasonable efforts to cause all such Registrable Securities covered by such registration statement to be listed
on a national securities exchange or trading system on which the Company’s securities are then listed;


 


3.1.8.           
provide a transfer agent and registrar for all Registrable Securities registered pursuant to this Agreement and, provided that
the Company’s securities are listed on a national securities exchange or trading system in the United States, provide a CUSIP number
for all such Registrable Securities, in each case not later than the effective date of such registration;


 


3.1.9.           
promptly make available for inspection by the selling Holders, any underwriter(s) participating in any disposition pursuant to
such registration statement, and any attorney or accountant or other agent retained by any such underwriter or selected by the selling
Holders, all financial and other records, pertinent corporate documents, and properties of the Company, reasonably required for such purposes
and cause the Company’s officers, directors, employees, and independent accountants to supply all information reasonably requested
by any such seller, underwriter, attorney, accountant, or agent, in each case, as reasonably
necessary or advisable to verify the accuracy of the information in such registration statement and to conduct appropriate due diligence
in connection therewith;


 


3.1.10.       
notify each selling Holder, promptly after the Company receives notice thereof, of the time when such registration statement has
been declared effective or a supplement to any prospectus forming a part of such registration statement has been filed;


 


3.1.11.       
after such registration statement becomes effective, notify each selling Holder of any request by the applicable securities exchange
commission that the Company amend or supplement such registration statement or prospectus;


 


3.1.12.       
notify each selling Holder of the happening of any event that would cause the prospectus included in an applicable registration
statement to contain an untrue statement of a material fact or omit any fact necessary in order to make the statements made therein, in
light of the circumstances under which they were made, not misleading, and, at the request of any such Holder, the Company shall prepare
a supplement or amendment to such prospectus so that, as thereafter delivered to the purchasers of such Registrable Securities, such prospectus
shall not contain an untrue statement of a material fact or omit to state any fact necessary to make the statements therein, in light
of the circumstances under which they were made, not misleading;


 


3.1.13.        comply
with all applicable rules and regulations of the SEC and make available to its shareholders an earnings statement (in a form that
satisfies the provisions of Section 11(a) of the Securities Act and Rule 158 under the Securities Act or any successor rule thereto)
no later than thirty (30) days after the end of the 12-month period beginning with the first day of the Company's first full fiscal
quarter after the effective date of each registration statement filed pursuant to this Agreement, which earnings statement shall
cover said 12-month period, and which requirement will be deemed to be satisfied if the Company timely files complete and accurate
information on Forms 10-K and 10-Q under the Exchange Act and otherwise complies with Rule 158 under the Securities Act or any
successor rule thereto;


 






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3.1.14.       
notify the Holders of Registrable Securities promptly of any request by the SEC for the amending or supplementing of any registration
statement or prospectus with respect to any Registrable Securities held by such Holders and included in such registration statement or
prospectus; and


 


3.1.15.       
advise the Holders of Registrable Securities, promptly after it shall receive notice or obtain knowledge thereof, of the issuance
of any stop order by the SEC suspending the effectiveness of any registration statement filed pursuant to this Agreement or the initiation
or threatening of any proceeding for such purpose and promptly use its reasonable best efforts to prevent the issuance of any stop order
or to obtain its withdrawal at the earliest possible moment if such stop order should be issued.


 


3.2.       
Furnish Information. It shall be a condition precedent to the obligations of the Company to take any action pursuant to
Section 3 hereof with respect to the Registrable Securities of any selling Holder, that such Holder shall furnish to the Company such
information regarding itself and the Registrable Securities held by it as is reasonably required to effect the registration of such Holder’s
Registrable Securities.


 


3.3.      
Expenses of Registration. All reasonable expenses (other than Selling Expenses) incurred in connection with registrations,
filings, or qualifications pursuant to Section 2 hereof, including all registration, filing, and qualification fees; printers’
and accounting fees; fees and disbursements of counsel for the Company; and the reasonable fees and disbursements of one counsel for the
selling Holders (“Selling Holder Counsel”), shall be borne and paid
by the Company. All Selling Expenses relating to Registrable Securities registered pursuant to Section 2 hereof shall be borne and
paid by the Holders pro rata on the basis of the number of Registrable Securities registered on their behalf. “Selling Expenses”
means all underwriting discounts, selling commissions, and stock transfer taxes applicable to the sale of Registrable Securities, and
fees and disbursements of counsel for any Holder, except for the fees and disbursements of
the Selling Holder Counsel borne and paid by the Company as provided in this Section 3.3.


 


4.             
Limitations on Subsequent Registration Rights. From and after the date of this Agreement, the Company shall not, without
the prior written consent of the Holders of a majority of the Registrable Securities then outstanding, enter into any agreement with any
holder or prospective holder of any securities of the Company that would allow such holder or prospective holder (i) to include such securities
in any registration unless, under the terms of such agreement, such holder or prospective holder may include such securities in any such
registration only to the extent that the inclusion of such securities will not reduce the number of the Registrable Securities of the
Holders that are included therein, or (ii) to demand registration of any securities held by such holder or prospective holder.


 


5.             
Right to Conduct Activities.


 


5.1.    Centillion. The
Company hereby acknowledges that Centillion Fund (“Centillion”) (and its Affiliates and their respective affiliated
advisors and funds) are professional investment managers and/or funds and/or operating companies, and as such, may invest in numerous
portfolio companies or operate businesses, some of which may be deemed competitive with the Company’s business (as conducted or
proposed to be conducted). Neither Centillion nor its respective Affiliates (including affiliated advisors and funds) shall be liable
to the Company for any claim arising out of, or based upon, (i) any lawful business operations or the investment by Centillion or any
affiliated funds in any entity competitive to the Company, or (ii) lawful actions taken by any advisor, partner, officer or other representative
of Centillion or any affiliated fund or any of their respective Affiliates to assist any such competitive company, whether or not such
action was taken as a board member of such competitive company, or otherwise, in each case provided that such business operations and
or actions do not involve use of proprietary information obtained directly as a result of being a shareholder (or having a board member
or observer) in the Company.


 






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5.2.    OrbiMed. The
Company hereby acknowledges that OrbiMed Israel Partners, Limited Partnership Ltd. (“OrbiMed”) (and its
Affiliates and their respective affiliated advisors and funds) are professional investment managers and/or funds and/or operating
companies, and as such, may invest in numerous portfolio companies or operate businesses, some of which may be deemed competitive
with the Company’s business (as conducted or proposed to be conducted). Neither OrbiMed nor its respective Affiliates
(including affiliated advisors and funds) shall be liable to the Company for any claim arising out of, or based upon, (i) any lawful
business operations or the investment by OrbiMed or any affiliated funds in any entity competitive to the Company, or (ii) lawful
actions taken by any advisor, partner, officer or other representative of OrbiMed or any affiliated fund or any of their respective
Affiliates to assist any such competitive company, whether or not such action was taken as a board member of such competitive
company, or otherwise, in each case provided that such business operations and or actions do not involve use of proprietary
information obtained directly as a result of being a shareholder (or having a board member or observer) in the Company.


 


5.3.    Rivendell. The
Company hereby acknowledges that Rivendell Investments 2017-9 LLC (“Rivendell”) (and its Affiliates and their respective
affiliated advisors and funds) are professional investment managers and/or funds and/or operating companies, and as such, may invest in
numerous portfolio companies or operate businesses, some of which may be deemed competitive with the Company’s business (as conducted
or proposed to be conducted). Neither Rivendell nor its respective Affiliates (including affiliated advisors and funds) shall be liable
to the Company for any claim arising out of, or based upon, (i) any lawful business operations or the investment by Rivendell or any affiliated
funds in any entity competitive to the Company, or (ii) lawful actions taken by any advisor, partner, officer or other representative
of Rivendell or any affiliated fund or any of their respective Affiliates to assist any such competitive company, whether or not such
action was taken as a board member of such competitive company, or otherwise, in each case provided that such business operations and
or actions do not involve use of proprietary information obtained directly as a result of being a shareholder (or having a board member
or observer) in the Company.


 


5.4.    SBI. The Company
hereby acknowledges that SBI JI Innovation Fund Limited Partnership (“SBI”), (and its Affiliates and their respective
affiliated advisors and funds) are professional investment managers and/or funds and/or operating companies, and as such, may invest in
numerous portfolio companies or operate businesses, some of which may be deemed competitive with the Company’s business (as conducted
or proposed to be conducted). Neither SBI nor its respective Affiliates (including affiliated advisors and funds) shall be liable to the
Company for any claim arising out of, or based upon, (i) any lawful business operations or the investment by SBI or any affiliated funds
in any entity competitive to the Company, or (ii) lawful actions taken by any advisor, partner, officer or other representative of SBI
or any affiliated fund or any of their respective Affiliates to assist any such competitive company, whether or not such action was taken
as a board member of such competitive company, or otherwise, in each case provided that such business operations and or actions do not
involve use of proprietary information obtained directly as a result of being a shareholder (or having a board member or observer) in
the Company.


 


5.5.    Milestone. The
Company hereby acknowledges that Milestone View Limited (“Milestone”) (and its Affiliates and their respective affiliated
advisors and funds) are professional investment managers and/or funds and/or operating companies, and as such, may invest in numerous
portfolio companies or operate businesses, some of which may be deemed competitive with the Company’s business (as conducted or
proposed to be conducted). Neither Milestone nor its respective Affiliates (including affiliated advisors and funds) shall be liable to
the Company for any claim arising out of, or based upon, (i) any lawful business operations or the investment by Milestone or any affiliated
funds in any entity competitive to the Company, or (ii) lawful actions taken by any advisor, partner, officer or other representative
of Milestone or any affiliated fund or any of their respective Affiliates to assist any such competitive company, whether or not such
action was taken as a board member of such competitive company, or otherwise, in each case provided that such business operations and
or actions do not involve use of proprietary information obtained directly as a result of being a shareholder (or having a board member
or observer) in the Company.


 






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5.6.
   Finteca. The Company hereby acknowledges that Finteca Holdings Limited (“Finteca”) (and
its Affiliates and their respective affiliated advisors and funds) are professional investment managers and/or funds and/or
operating companies, and as such, may invest in numerous portfolio companies or operate businesses, some of which may be deemed
competitive with the Company’s business (as conducted or proposed to be conducted). Neither Finteca nor its respective
Affiliates (including affiliated advisors and funds) shall be liable to the Company for any claim arising out of, or based upon, (i)
any lawful business operations or the investment by Finteca or any affiliated funds in any entity competitive to the Company, or
(ii) lawful actions taken by any advisor, partner, officer or other representative of Finteca or any affiliated fund or any of their
respective Affiliates to assist any such competitive company, whether or not such action was taken as a board member of such
competitive company, or otherwise, in each case provided that such business operations and or actions do not involve use of
proprietary information obtained directly as a result of being a shareholder (or having a board member or observer) in the
Company.


 


6.             
Term. This Agreement shall be effective as of the date hereof and shall continue in effect until the earliest to occur of
(a) five (5) years following the Effective Date, provided that the provisions of Section 7 hereof will continue after such time to the
extent necessary to enforce the provisions of this Agreement and (b) termination of this Agreement in accordance with Section 7.6 (‘Consent
Required to Amend, Terminate or Waive’) below.


 


7.             
Miscellaneous.


 


7.1.       
Successors and Assigns. The rights under this Agreement may be assigned (but only with all related obligations) by a Holder
to a transferee of Registrable Securities that (i) is a Permitted Transferee of the Holder; or (ii) after such transfer, holds at least
ten percent (10%) of the Registrable Securities (as adjusted for any share split, share dividend, bonus share issuance, recapitalization
or similar transaction); provided, however, that (x) the Company is, within a reasonable time after such transfer, furnished with written
notice of the name and address of such transferee and the Registrable Securities with respect to which such rights are being transferred;
and (y) such transferee agrees in a written instrument delivered to the Company to be bound by and subject to the terms and conditions
of this Agreement. For the purposes of determining the number of shares of Registrable Securities held by a transferee, the holdings of
a transferee that is a permitted Transferee shall be aggregated together and with those of the transferring Holder; provided further that
all transferees who would not qualify individually for assignment of rights shall have a single attorney-in-fact for the purpose of exercising
any rights, receiving notices, or taking any action under this Agreement. The terms and conditions of this Agreement inure to the benefit
of and are binding upon the respective successors and permitted assignees of the parties. Nothing in this Agreement, express or implied,
is intended to confer upon any party other than the parties hereto or their respective successors and permitted assignees any rights,
remedies, obligations or liabilities under or by reason of this Agreement, except as expressly provided herein.


 


7.2.       
Governing Law; Jurisdiction. This Agreement and any controversy arising out of or relating to this Agreement shall be governed
by and construed in accordance with the internal laws of the State of Israel, without regard to conflict of law principles that would
result in the application of any law other than the law of the State of Israel. The parties (a) hereby irrevocably and unconditionally
submit to the jurisdiction of the competent courts of Tel Aviv-Jaffa, Israel for the purpose of any suit, action or other proceeding arising
out of or based upon this Agreement, (b) agree not to commence any suit, action or other proceeding arising out of or based upon this
Agreement except in the competent courts of Tel Aviv-Jaffa, Israel.


 


7.3.       
Counterparts; Facsimile. This Agreement may be executed and delivered by facsimile signature and in two or more counterparts,
each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.


 


7.4.       
Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not to be considered
in construing or interpreting this Agreement.


 


7.5.       
Notices. All notices and other communications given or made pursuant to this Agreement shall be in writing and shall be
deemed effectively given: (a) upon personal delivery to the party to be notified, (b) when sent by confirmed electronic mail or facsimile
if sent during normal business hours of the recipient, and if not so confirmed, then on the next business day, (c) five (5) days after
having been sent by registered or certified mail, return receipt requested, postage prepaid, or (d) one (1) business day after the business
day of deposit with a nationally recognized overnight courier, specifying next business day delivery, with written verification of receipt.
All communications shall be sent to the respective parties at their address as kept on record with the Company, or to such email address,
facsimile number or address as subsequently modified by written notice given in accordance with this Section 7.5.


 






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7.6.       
 Consent Required to Amend, Terminate or Waive. This Agreement may be amended or modified and the observance of any term
hereof may be waived (either generally or in a particular instance and either retroactively or prospectively) only by a written instrument
executed by (a) the Company, and (ii) Shareholders holding a majority of the Shares then held by Shareholders; provided, that if such
amendment or waiver would adversely and disproportionately modify the rights or obligations of any Shareholder holding Registrable Securities
vis-à-vis any other Shareholder holding Registrable Securities, then such amendment shall require the prior consent of any such
affected Shareholder. Notwithstanding the foregoing: (i) Schedule A hereto may be amended by the Company from time to time to
add information regarding additional Shareholders (that are assignees and/or Permitted Transferees pursuant to Section 7.1 hereof) without
the consent of the other parties hereto; (ii) any provision hereof may be waived by the waiving party on such party’s own behalf,
without the consent of any other party. A copy of any amendment shall be delivered to each Shareholder within five business days of the
effectiveness of such amendment.


 


The Company shall give prompt
written notice of any amendment, termination or waiver hereunder to any party that did not consent in writing thereto. Any amendment,
termination or waiver effected in accordance with this Section 7.6 shall be binding on each party and all of such party’s successors
and permitted assigns, whether or not any such party, successor or assignee entered into or approved such amendment, termination or waiver.


 


7.7.       
Delays or Omissions. No delay or omission to exercise any right, power or remedy accruing to any party under this Agreement,
upon any breach or default of any other party under this Agreement, shall impair any such right, power or remedy of such non-breaching
or non-defaulting party nor shall it be construed to be a waiver of any such breach or default, or an acquiescence therein, or of or in
any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other
breach or default previously or thereafter occurring. Any waiver, permit, consent or approval of any kind or character on the part of
any party of any breach or default under this Agreement, or any waiver on the part of any party of any provisions or conditions of this
Agreement, must be in writing and shall be effective only to the extent specifically set forth in such writing. All remedies, either under
this Agreement or by law or otherwise afforded to any party, shall be cumulative and not alternative.


 


7.8.       
Severability. The invalidity or unenforceability of any provision hereof shall in no way affect the validity or enforceability
of any other provision.


 


7.9.       
Entire Agreement. This Agreement (including any Schedules and Exhibits hereto), constitute the full and entire understanding
and agreement between the parties with respect to the subject matter hereof, and any other written or oral agreement relating to the subject
matter hereof existing between the parties are expressly canceled, including without limitation the Prior Agreement, which is hereby terminated
and of no further force and effect.


 


7.10.    
Share Splits, Share Dividends, etc. In the event of any issuance of Shares of the Company’s voting securities hereafter
to any of the Shareholders (including, without limitation, in connection with any share split, share dividend, recapitalization, reorganization,
or the like), such Shares shall become subject to this Agreement.


 


7.11.    
Manner of Voting. The voting of Shares pursuant to this Agreement may be effected in person, by proxy, by written consent
or in any other manner permitted by applicable law and Articles of Association of the Company then in effect.


 


7.12.    
Further Assurances. At any time or from time to time after the date hereof, the parties agree to cooperate with each other,
and at the request of any other party, to execute and deliver any further instruments or documents and to take all such further action
as the other party may reasonably request in order to evidence or effectuate the consummation of the transactions contemplated hereby
and to otherwise carry out the intent of the parties hereunder.


 


7.13.     Aggregation
of Shares. All shares of Registrable Securities held or acquired by Shareholders who are Permitted Transferees shall be
aggregated together for the purpose of determining the availability of any rights under this Agreement and such Shareholders who are
Permitted Transferees may apportion such rights as among themselves in any manner they deem appropriate.


 


7.14.    
Termination of Existing Registration Rights Agreement. By executing and delivering this Agreement, those Shareholders party
hereto, who collectively constitute the requisite “Majority Investors” under the Existing Registration Rights Agreement, together
with (i) the Target Company and (ii) the founder of the Target Company who is party to the Existing Registration Rights Agreement, hereby
terminate the Existing Registration Rights Agreement, pursuant to Section 3.7 thereof, effective as of the Effective Date of this Agreement.
Each of the Target Company and the foregoing founder of the Target Company is executing and delivering this Agreement for the sole purpose
of acknowledging, and agreeing to, the provisions of this Section 7.14. 


 


[Signature Pages Follow]


 






    - 15 -


     


    

 


IN WITNESS WHEREOF,
the parties hereto have duly executed this Registration Rights Agreement effective as of the Effective Date appearing above.


 


	Anchiano Therapeutics Ltd.    	 
	 	 
	By:	/s/ Neil Cohen	 
	Name:  	Neil Cohen	 
	Title:	Chief Executive Officer	 
	 	 
	By:	/s/ Andrew Fine	 
	Name:	Andrew Fine	 
	Title:	Chief Financial Officer	 



 






     

     


    

 


IN WITNESS WHEREOF,
the parties hereto have duly executed this Registration Rights Agreement effective as of the Effective Date appearing above.


 


 


	Finteca Holdings Limited  	 	Centillion Fund Inc.   
	 	 	 
	By:	 /s/ Sean Ellis	 	By:	/s/ Sean Ellis
	Name:	 Sean Ellis	 	Name:	Sean Ellis
	Title:	     	 	Title:	 
	 	 	 
	Rivendell Investments 2017-9 LLC    	 	OrbiMed Partners Limited Partnership     
	 	 	 
	By:	/s/ Jory Shoell	 	By:	/s/ Nissim Darvish /s/ Erez Chimovits
	Name:	Jory Shoell	 	Name:	Nissim Darvish Erez Chimovits
	Title:	Authorized Signatory      	 	Title:	Senior Managing Director Director  
	 	 	 
	Apeiron SICAV Ltd. – Presight Capital Fund ONE      	 	SBI JI Innovation Fund LP    
	 	 	 
	By:	/s/ Heinz Daxl /s/ Jefim Gewiet	 	By:	/s/ Ryo Nakashima
	Name:  	Heinz Daxl Jefim Gewiet	 	Name:  	Ryo Nakashima
	Title:	Director Director	 	Title:	Director of GP



 






     

     


    

 


IN WITNESS WHEREOF, the parties hereto
have duly executed this Registration Rights Agreement effective as of the Effective Date appearing above.


 


	FOUNDERS	 
	 	 
	/s/
    Adi Mor	 
	Adi
    Mor	 
	 	 
	/s/
    Kobi George	 
	Kobi
    George	 




 






     

     


    

 


ACKNOWLEDGED AND AGREED, solely with respect
to the final “WHEREAS” clause and Section 7.14 of this Registration Rights Agreement, effective as of the Effective Date appearing
above.


 


	CHEMOMAB
    LTD.	 
	 	 
	By: 	/s/ Adi Mor	 
	Name:   	Adi Mor	 
	Title: 	CEO