EXHIBIT 31.1




CERTIFICATION




I, Steve
H. Kanzer, certify that:




1. I have reviewed this quarterly
report on Form 10-Q of Pipex Pharmaceuticals, Inc.;




2. Based on my knowledge, this
report does not contain any untrue statement of a material fact or omit to state
a material fact necessary to make the statements made, in light of the
circumstances under which such statements were made, not misleading with respect
to the period covered by this report;




3. Based on my knowledge, the
financial statements, and other financial information included in this report,
fairly present in all material respects the financial condition, results of
operations and cash flows of the small business issuer as of, and for, the
periods presented in this report;




4. I am responsible for
establishing and maintaining disclosure controls and procedures (as defined in
Exchange Act Rules 13a-15(e) and 15d-15(e))  and internal control over
financial reporting (as definded in Exchange Act Rules 13a-15(f) and
15d-15(f) for the small business issuer and have:




a)
Designed such disclosure controls and procedures, or caused such disclosure
controls and procedures to be designed under my supervision, to ensure that
material information relating to the small business issuer, including its
consolidated subsidiaries, is made known to me by others within those entities,
particularly during the period in which this report is being
prepared;




b)
Designed such internal control over financial reporting, or caused such internal
control over financial reporting to be designed under my supervision, to provide
reasonable assurance regarding the reliability of financial reporting and the
preparation of financial statements for external purposes in accordance with
generally accepted accounting principles;


c)
Evaluated the effectiveness of the small business issuer’s disclosure controls
and procedures and presented in this report my conclusions about the
effectiveness of the disclosure controls and procedures, as of the end of the
period covered by this report based on such evaluation; and




d)
Disclosed in this report any change in the small business issuer’s internal
control over financial reporting that occurred during the small business
issuer’s most recent fiscal quarter (the small business issuer’s fourth fiscal
quarter in the case of an annual report) that has materially affected, or is
reasonably likely to materially affect, the small business issuer’s internal
control over financial reporting; and




5. I have disclosed, based on my
most recent evaluation of internal control over financial reporting, to the
small business issuer’s auditors and the audit committee of the small business
issuer’s board of directors (or persons performing the equivalent
functions):




a) All
significant deficiencies and material weaknesses in the design or operation of
internal control over financial reporting which are reasonably likely to
adversely affect the small business issuer’s ability to record, process,
summarize and report financial information; and




b) Any
fraud, whether or not material, that involves management or other employees who
have a significant role in the small business issuer ‘s internal control over
financial reporting.




Date: May
15, 2008




By:/s/ Steve H.
Kanzer


Name:
Steve H. Kanzer


Title:
Chairman & Chief Executive Officer


(Principal
Executive Officer and Principal Financial Officer)