Exhibit 4.1

                                 Form of Warrant

THE WARRANT REPRESENTED BY THIS CERTIFICATE AND THE SECURITIES ISSUABLE UPON
EXERCISE THEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR
THE SECURITIES LAWS OF ANY STATE. NEITHER THE WARRANT NOR SUCH SECURITIES MAY BE
SOLD, PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED WITHOUT SUCH REGISTRATION,
EXCEPT UPON DELIVERY TO THE COMPANY OF SUCH EVIDENCE AS MAY BE SATISFACTORY TO
COUNSEL FOR THE COMPANY TO THE EFFECT THAT ANY SUCH TRANSFER IS NOT IN VIOLATION
OF THE SECURITIES ACT OF 1933 OR APPLICABLE STATE SECURITIES LAWS OR ANY RULE OR
REGULATION PROMULGATED THEREUNDER.

                             AVAX TECHNOLOGIES, INC.

                      Series 2000 Warrant for the Purchase
                            of Shares of Common Stock

No. GW - ___                                                   Delaware, U.S.A.

      FOR VALUE RECEIVED, AVAX TECHNOLOGIES, INC., a Delaware corporation (the
"Company"), hereby certifies that ___________ (the "Holder"), its designee or
its permitted assigns is entitled to purchase from the Company, at any time or
from time to time commencing on March 10, 2000 and prior to 5:00 P.M., New York
City time, on March 10, 2005, up to ___________ (___________) fully paid and
non-assessable shares of common stock (subject to adjustment), $.004 par value
per share, of the Company for $12.79 per share (subject to adjustment) at an
aggregate purchase price of $[_________]. This Warrant, all similar Warrants
issued in accordance with the Purchase Agreement referred to herein, and all
warrants hereafter issued in exchange or substitution for this Warrant or
similar Warrants are referred to as the "Warrants;" common stock, $.004 par
value per share, of the Company, is referred to as the "Common Stock;" the
shares of the Common Stock purchasable hereunder or under any other Warrant (as
hereinafter defined) are referred to as the "Warrant Shares;" the aggregate
purchase price payable for the Warrant Shares purchasable hereunder is referred
to as the "Aggregate Warrant Price;" the price payable (initially $12.79 per
share, subject to adjustment) for each of the Warrant Shares is referred to as
the "Per Share Warrant Price;" the holder of this Warrant is referred to as the
"Holder;" the holder of this Warrant and all other Warrants and Warrant Shares
are referred to as the "Holders;" and Holders of more than 50% of the
outstanding Warrants are referred to as the "Majority of the Holders"). The
Aggregate Warrant Price is not subject to adjustment.

      This Warrant, together with Warrants of like tenor, constituting in the
aggregate Warrants to purchase __________ Warrant Shares, was originally issued
pursuant to a Securities Purchase Agreement dated as of March 7, 2000 (the
"Purchase Agreement") among the Company and the purchasers named therein. By
acceptance of this Warrant, the Holder agrees to comply with all applicable
provisions of the Purchase Agreement to the same extent as if it were a party
thereto.


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      1. Exercise of Warrant. (a) This Warrant may be exercised in whole at any
time, or in part from time to time, commencing on March 10, 2000 and prior to
5:00 P.M., New York City time, on March 10, 2005 by the Holder by the surrender
of this Warrant (with the subscription form at the end hereof duly executed) at
the address set forth in Section 9(a), together with proper payment of the
Aggregate Warrant Price, or the proportionate part thereof if this Warrant is
exercised in part, with payment for the Warrant Shares made by certified or
official bank check payable to the order of the Company; or

      (b) If this Warrant is exercised in part, this Warrant must be exercised
for a number of whole shares of the Common Stock and the Holder is entitled to
receive a new Warrant covering the Warrant Shares that have not been exercised
and setting forth the proportionate part of the Aggregate Warrant Price
applicable to such Warrant Shares.

      (c) Upon surrender of this Warrant, the Company will (i) issue a
certificate or certificates in the name of the Holder for the number of whole
shares of the Common Stock to which the Holder is entitled and, if this Warrant
is exercised in whole, in lieu of any fractional share of the Common Stock to
which the Holder may be entitled, pay to the Holder cash in an amount equal to
the fair value of the fractional share (determined in such reasonable manner as
the Board of Directors of the Company determines), and (ii) to the extent
applicable, deliver the other securities and properties receivable upon the
exercise of this Warrant, or the proportionate part thereof if this Warrant is
exercised in part, pursuant to the provisions of this Warrant.

      2. Reservation of Warrant Shares; Listing. The Company agrees that, prior
to the expiration of this Warrant, the Company shall at all times (i) have
authorized and in reserve, and shall keep available, solely for issuance and
delivery upon the exercise of this Warrant, the shares of the Common Stock and
other securities and properties as from time to time shall be receivable upon
the exercise of this Warrant, free and clear of all restrictions on sale or
transfer, other than under Federal or state securities laws, and free and clear
of all preemptive rights and rights of first refusal and (ii) use its best
efforts to keep the Warrant Shares authorized for listing on the Nasdaq National
Market, the Nasdaq SmallCap Market or any national securities exchange on which
the Company's Common Stock is traded.

      3. Protection Against Dilution. (a) If the Company hereafter (i) pays a
dividend or makes a distribution on its Common Stock in shares of Common Stock,
(ii) subdivides its outstanding shares of Common Stock into a greater number of
shares, (iii) combines its outstanding shares of Common Stock into a smaller
number of shares or (iv) issues by reclassification of its Common Stock any
shares of capital stock of the Company, then (x) the Per Share Warrant Price
(but not the Aggregate Warrant Price) and (y) the number of Warrant Shares
issuable hereunder (collectively the "Exercise Terms") shall be adjusted so that
the Holder upon the exercise hereof will be entitled to receive the number of
shares of Common Stock or other capital stock of the Company that the Holder
would have owned immediately following such action had the Warrant been
exercised immediately prior thereto. An adjustment made pursuant to this Section
3(a) will become effective immediately after the record date in the case of a
dividend or distribution and will become effective immediately after the
effective date in the case of a subdivision, combination or reclassification. If
the Board of Directors of the Company declares any dividend or distribution or
resolve to take any action referred to in this Section 3(a), it shall provide
written notice thereof to the Holders not less than 10 days prior to the record
date fixed for determining the stockholders entitled to participate therein.

      (b) In the case of any capital reorganization or reclassification, or any
consolidation or merger to which the Company is a party, other than a merger or
consolidation in which the Company


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<PAGE>

is the continuing corporation, or in the case of any sale or conveyance to
another entity of the property of the Company as an entirety or substantially as
an entirety, or in the case of any statutory exchange of securities with another
corporation (including any exchange effected in connection with a merger of a
third corporation into the Company), the Holder will have the right thereafter
to receive on the exercise of the Warrant the kind and amount of securities,
cash or other property that the Holder would have owned or have been entitled to
receive immediately after such reorganization, reclassification, consolidation,
merger, statutory exchange, sale or conveyance had the Warrant been exercised
immediately prior to the effective date of the reorganization, reclassification
consolidation, merger, statutory exchange, sale or conveyance and in any such
case, if necessary, appropriate adjustment shall be made in the application of
the provisions set forth in this Section 3 with respect to the rights and
interests thereafter of the Holder to the end that the provisions set forth in
this Section 3 shall thereafter correspondingly be made applicable, as nearly as
may reasonably be, in relation to any shares of stock or other securities
thereafter deliverable on the exercise of the Warrant. Notice of any such
reorganization, reclassification, consolidation, merger, exchange, sale or
conveyance shall be mailed to the Holders not less than 30 days prior to such
event. The above provisions of this Section 3(b) shall similarly apply to
successive reorganizations, reclassifications, consolidations, mergers,
statutory exchanges, sales or conveyances. The Company shall require the issuer
of any shares of stock or other securities or property thereafter deliverable on
the exercise of the Warrants to be responsible for all of the agreements and
obligations of the Company hereunder.

      (c) If the Company issues rights, options, warrants or convertible
securities to all holders of its Common Stock, without any charge to or
consideration from such holders, entitling them to subscribe for or purchase
Common Stock at a price per share that is lower at the record date mentioned
below than the closing bid price (as defined below) for the trading day
immediately prior to such record date (the "Current Market Price"), then the Per
Share Warrant Price shall be determined by multiplying the Per Share Warrant
Price then in effect by a fraction, of which the numerator is the number of
shares of Common Stock outstanding immediately prior to the issuance of such
rights, options, warrants or convertible securities plus the number of
additional shares of Common Stock offered for subscription or purchase, and of
which the denominator is the number of shares of Common Stock outstanding
immediately prior to the issuance of such rights, options, warrants or
convertible securities plus the number of shares which the aggregate offering
price of the total number of shares offered would purchase at such Current
Market Price. Such adjustment shall be made whenever such rights, options,
warrants or convertible securities are issued, and shall become effective
immediately and retroactive to the record date for the determination of
stockholders entitled to receive such rights, options, warrants or convertible
securities.

      The "closing bid price" for each trading day shall be the reported closing
bid price on the NASDAQ SmallCap Market or the NASDAQ National Market System
("NMS") (such markets are collectively referred to as "NASDAQ") or, if the
Common Stock is not quoted on NASDAQ, on the principal national securities
exchange on which common stock is listed or admitted to trading (based on the
aggregate dollar value of all securities listed or admitted to trading) or, if
not listed or admitted to trading on any national securities exchange or quoted
on NASDAQ, the closing bid price in the over-the-counter market as furnished by
any NASD member firm selected from time to time by the Company for that purpose,
or, if such prices are not available, the fair market value set by, or in a
manner established by, the Board of Directors of the Company in good faith.
"Trading day" shall mean a day on which the national securities exchange or
NASDAQ used to determine the closing bid price is open for the transaction of
business or the reporting of trades or, if the closing bid price is not so
determined, a day on which NASDAQ is open for the transaction of business.


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      (d) If the Company distributes (other than a distribution in liquidation
of the Company) to all holders of its Common Stock, without any charge to or
consideration from such holder, evidences of its indebtedness or assets
(excluding cash dividends or distributions out of earnings), then in each case
the Company shall simultaneously distribute such evidences of its indebtedness
or assets pro rata to the Holders of Warrants on the record date or date of
effectiveness, as the case may be, fixed for determining the holders of Common
Stock entitled to participate in such distribution in an amount equal to the
amount that such Holders would have been entitled to receive had their Warrants
been exercised for shares of Common Stock immediately prior to the time for
determination of the holders of Common Stock entitled to participate in that
distribution.

      (e) No adjustments in the Exercise Terms shall be required:

            (i) Unless such adjustment would require an increase or decrease of
      at least $0.05 per share of Common Stock; provided, however, that any
      adjustments that by reason of this Section 3(e)(i) are not required to be
      made shall be carried forward and cumulated with amounts in any subsequent
      adjustment, and provided, further, however, that adjustments shall be
      required and made in accordance with the provisions of this Section 3
      (other than this Section 3(e)(i)) not later than such time as may be
      required in order to preserve the tax-free nature of a distribution to the
      Holder of this Warrant or Common Stock issuable upon the exercise hereof.
      All calculations that shall be required pursuant to this Section 3 shall
      be made to the nearest cent or to the nearest one-hundredth of a share, as
      the case may be. Anything in this Section 3 to the contrary
      notwithstanding, the Company shall be entitled to make such adjustments to
      the Exercise Terms, in addition to those required by this Section 3 as it
      in its discretion shall deem to be advisable in order that any stock
      dividend, subdivision of shares or distribution of rights to purchase
      stock or securities convertible or exchangeable for stock hereafter made
      by the Company to its stockholders is not taxable;

            (ii) If the Company issues shares of Common Stock pursuant to (a)
      the exercise of any warrants (or warrants or options to acquire any shares
      of convertible preferred stock) of the Company outstanding on the date
      hereof, (b) the exercise of the Warrants, or a portion thereof, (c) the
      conversion of shares of any series of convertible preferred stock of the
      Company outstanding on the date hereof, (d) the exercise of any stock
      options or warrants currently outstanding or issued after the date hereof
      pursuant to any Company benefit plan or compensation arrangement, or (e)
      the exercise of any warrants issued to Gruntal & Co. LLC in connection
      with the transactions contemplated by the Purchase Agreement.

      (f) Whenever the conversion rate is adjusted as provided in any provision
of this Section 3:

                  (i) the Company shall compute (or at the request of a Majority
of Holders shall retain a firm of independent public accountants (which may be
any such firm regularly employed by the Company) to compute) the adjusted
Exercise Terms in accordance with this Section 3 and shall prepare a certificate
signed by the principal financial officer of the Company (or cause any such
independent public accountants to execute a certificate) setting forth the
adjusted conversion rate and showing in reasonable detail the facts upon which
such adjustment is based, and such certificate shall forthwith be filed with the
registrar of the Warrant; and

                  (ii) the Company shall mail as soon as practicable after an
adjustment is required a notice stating that the Exercise Terms have been
adjusted and setting forth the adjusted Exercise Terms to all record holders of
Warrants at their last addresses as they shall appear in the records of the
Company.


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      4. Fully Paid Stock; Taxes. The shares of the Common Stock represented by
each certificate for Warrant Shares delivered on the exercise of this Warrant
shall at the time of such delivery, be duly authorized, validly issued and
outstanding, fully paid and nonassessable, and not subject to preemptive rights
or rights of first refusal, and the Company will take all such actions as may be
necessary to assure that the par value, if any, per share of the Common Stock is
at all times equal to or less than the then Per Share Warrant Price. The Company
shall pay all documentary, stamp or similar taxes and other similar governmental
charges that may be imposed with respect to the issuance or delivery of any
shares of Common Stock upon exercise of the Warrant (other than income taxes);
provided, however, that if the shares of Common Stock are to be delivered in a
name other than the name of the Holder, no such delivery shall be made unless
the person requesting the same has paid to the Company the amount of transfer
taxes or charges incident thereto, if any.

      5. Registration Under Securities Act of 1933. (a) The Holder shall have
the right to participate in the registration rights granted to Holders of
Registrable Securities (as defined in the Purchase Agreement) with respect to
the Warrant Shares, pursuant to Section 7 of the Purchase Agreement. By
acceptance of this Warrant, the Holder agrees to comply with the provisions of
Section 7 of the Purchase Agreement to the same extent as if it were a party
thereto.

      (b) Until all of the Warrant Shares have been sold under a registration
statement declared effective by the Securities and Exchange Commission or
pursuant to Rule 144, the Company shall use its reasonable best efforts to file
with the Securities and Exchange Commission all current reports and the
information as may be necessary to enable the Holder to effect sales of its
shares in reliance upon Rule 144 promulgated under the Securities Act of 1933,
as amended (the "Act").

      6. Investment Intent; Limited Transferability. (a) The Holder represents,
by accepting this Warrant, that it understands that this Warrant and any
securities obtainable upon exercise of this Warrant have not been registered for
sale under Federal or state securities laws and are being offered and sold to
the Holder pursuant to one or more exemptions from the registration requirements
of such securities laws. In the absence of an effective registration of such
securities or an exemption therefrom, any certificates for such securities shall
bear the legend set forth on the first page hereof. The Holder understands that
it must bear the economic risk of its investment in this Warrant and any
securities obtainable upon exercise of this Warrant for an indefinite period of
time, as this Warrant and such securities have not been registered under Federal
or state securities laws and therefore cannot be sold unless subsequently
registered under such laws, unless an exemption from such registration is
available.

      (b) The Holder, by its acceptance of this Warrant, represents to the
Company that it is acquiring this Warrant and will acquire any securities
obtainable upon exercise of this Warrant for its own account for investment and
not with a view to, or for sale in connection with, any distribution thereof in
violation of the Act. The Holder agrees that this Warrant and any such
securities will not be sold or otherwise transferred unless (i) a registration
statement with respect to such transfer is effective under the Act and any
applicable state securities laws or (ii) such sale or transfer is made pursuant
to one or more exemptions from the Act.

      (c) This Warrant may not be sold, transferred, assigned or hypothecated by
the Holder except in compliance with the provisions of the Act and the
applicable state securities "blue sky" laws, and is transferable only upon the
books of the Company, which it shall cause to be maintained for such purpose.
The Company may treat the registered Holder of this Warrant as he, she or it
appears on the Company's books at any time as the Holder for all purposes. The
Company shall permit any Holder of a Warrant or his duly authorized attorney,
upon written request during ordinary business hours, to inspect and copy or make
extracts from its books showing the registered holders of Warrants. All Warrants
issued upon the


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transfer or assignment of this Warrant will be dated the same date as this
Warrant, and all rights of the holder thereof shall be identical to those of the
Holder.

      7. Loss, etc., of Warrant. Upon receipt of evidence satisfactory to the
Company of the loss, theft, destruction or mutilation of this Warrant, and of
indemnity reasonably satisfactory to the Company, if lost, stolen or destroyed,
and upon surrender and cancellation of this Warrant, if mutilated, the Company
shall execute and deliver to the Holder a new Warrant of like date, tenor and
denomination.

      8. Warrant Holder Not Stockholder. This Warrant does not confer upon the
Holder any right to vote on or consent to or receive notice as a stockholder of
the Company, as such, in respect of any matters whatsoever, nor any other rights
or liabilities as a stockholder, prior to the exercise hereof; this Warrant
does, however, require certain notices to Holders as set forth herein.

      9. Communication. Any notice or other communication shall be effective and
shall be deemed to have been given if, the same is in writing and is mailed by
first-class mail, postage prepaid, addressed to:

      (a) the Company at AVAX Technologies, Inc.,4520 Main Street, Suite 930,
Kansas City, MO 64111, Attn: Jeffrey M. Jonas, M.D., President and Chief
Executive Officer, or such other address as the Company has designated in
writing to the Holder, or

      (b) the Holder at [INSERT ADDRESS] or other such address as the Holder has
designated in writing to the Company.

      10. Headings. The headings of this Warrant have been inserted as a matter
of convenience and shall not affect the construction hereof.

      11. Applicable Law. This Warrant shall be governed by and construed in
accordance with the laws of the State of Delaware without giving effect to the
principles of conflicts of law thereof.

                  [Remainder of page left blank intentionally.]


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      12. Amendment, Waiver, etc. Except as expressly provided herein, neither
this Warrant nor any term hereof may be amended, waived, discharged or
terminated other than by a written instrument signed by the party against whom
enforcement of any such amendment, waiver, discharge or termination is sought;
provided, however, that any provisions hereof may be amended, waived, discharged
or terminated upon the written consent of the Company and the Majority of the
Holders.

      IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by
its President and attested by its Secretary this 10th day of March, 2000.

                             AVAX TECHNOLOGIES, INC.


                                By:_____________________________________
                                Name:  Jeffrey M. Jonas, M.D.
                                Title: President and Chief Executive Officer
ATTEST:


___________________________
      Secretary


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<PAGE>

                               EXERCISE OF WARRANT

      The undersigned, ___________________, pursuant to the provisions of the
foregoing Warrant, hereby elects to purchase ____________________ shares of the
Common Stock, par value $.004 per share, of AVAX Technologies, Inc. covered by
said Warrant, and makes payment therefor in full at the Per Share Warrant Price
provided in the Warrant.

Dated:_______________               Signature:___________________________

                                    Address:_____________________________


                                   ASSIGNMENT

      FOR VALUE RECEIVED, _______________ hereby sells, assigns and transfers
unto ____________________ the foregoing Warrant and all rights evidenced
thereby, and does irrevocably constitute and appoint _____________________,
attorney, to transfer said Warrant on the books of AVAX Technologies, Inc.

Dated:_______________               Signature:___________________________

                                    Address:_____________________________


                               PARTIAL ASSIGNMENT

      FOR VALUE RECEIVED, _______________ hereby assigns and transfers unto
____________________ the right to purchase _______ shares of Common Stock, par
value $.004 per share, of AVAX Technologies, Inc. covered by the foregoing
Warrant, and a proportionate part of said Warrant and the rights evidenced
thereby, and does irrevocably constitute and appoint ____________________,
attorney, to transfer such part of said Warrant on the books of the Company.

Dated:_______________               Signature:___________________________

                                    Address:_____________________________


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