Exhibit 31.1

Certification of Principal Executive
OfficerPursuant to Section 302 of theSarbanes-Oxley Act of 2002

I, Edward J. Quilty, certify that:

1.    
          I have reviewed this quarterly report on Form 10-QSB of Derma Sciences, Inc.
          (the Registrant);

2.    
          Based on my knowledge, this quarterly report does not contain any untrue
          statement of a material fact or omit to state a material fact necessary to make
          the statements made, in light of the circumstances under which such statements
          were made, not misleading with respect to the period covered by this quarterly
          report;

3.    
          Based on my knowledge, the financial statements, and other financial information
          included in this quarterly report, fairly present in all material respects the
          financial condition, results of operations and cash flows of the Registrant as
          of, and for, the periods presented in this quarterly report;

4.    
          The Registrants other certifying officer and I are responsible for
          establishing and maintaining disclosure controls and procedures (as defined in
          Exchange Act Rules 13a-15(e) and 15d-15(e)) for the Registrant and have:

| | (a) |  | Designed
such disclosure controls and procedures, or caused such disclosure controls and
procedures to be designed under our supervision, to ensure that material information
relating to the Registrant, including its consolidated subsidiaries, is made known to us
by others within those entities, particularly during the period in which this report is
being prepared;
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| | (b) |  | Evaluated
the effectiveness of the Registrants disclosure controls and procedures and
presented in this report our conclusions about the effectiveness of the disclosure
controls and procedures, as of the end of the period covered by this report based on such
evaluation; and
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| | (c) |  | Disclosed
in this report any change in the Registrants internal control over financial
reporting (as defined in Exchange Act Rules 13(a)-15(f) and 15d-15(f)) that occurred
during the Registrants most recent fiscal quarter that has materially affected, or
is reasonably likely to materially affect, the Registrants internal control over
financial reporting; and
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5.    
          The Registrants other certifying officer and I have disclosed, based on
          our most recent evaluation of internal control over financial reporting, to the
          Registrants auditors and the audit committee of the Registrants
          board of directors (or persons performing the equivalent functions):

| | (a) |  | All
significant deficiencies and material weaknesses in the design or operation of internal
control over financial reporting which are reasonably likely to adversely affect the
Registrants ability to record, process, summarize and report financial information;
and
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| | (b) |  | Any
fraud, whether or not material, that involves management or other employees who have a
significant role in the Registrants internal control over financial reporting.
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|Dated:  May 14, 2007 | /s/ Edward J. Quilty                                                                                           | 
|                     | Edward J. Quilty
        Chairman, President and Chief Executive Officer
        (Principal Executive Officer) |