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| If      to Company:     |         | Idenix      Pharmaceuticals, Inc.                              |
|---------------------------------------------|--------------|----------------------------------------------------------------|
|                                        |         | One      Kendall Square, Building 1400                         |
|                                        |         | Cambridge,      MA 02139, USA                                  |
|                                        |         | Attn:      John Sullivan-Bolyai                                |
|                                        |         | Fax:      617-995-9817                                         |
|                                        |         |                                                           |
| with      a copy to:                        |         | Idenix      Sarl – Cap Gamma                        |
|                                        |         | 1682      Rue de la Valsiere                                   |
|                                        |         | BP      5001                                                   |
|                                        |         | 34189      Montpellier Cedex 4France                           |
|                                        |    | Attn:      Marie-Francoise TemamFax:      +33 (0)4 99 64 27 27 |

----

----

| IDENIX      PHARMACEUTICALS, INC.            |   | ACLIRES      INTERNATIONAL, LTD    |
|----------------------------------------------|--------|------------------------------------|
|                                         |   |                               |   |   |
|                                         |   |                               |   |   |
| By:                                          |        |                               | By: |  |
|                                         |   |                               |   |   |
| Name:      John Sullivan-Bolyai              |   | Name:      Robert Murphy           |
|                                         |   |                               |
| Title:      Vice President Clinical Research |   | Title:      Chief ExecutiveOfficer |

----

|   | i. |     Site      identification |
|--------|----|--------------------------------------------------|

|   | ii. |     Regulatory      activities |
|--------|-----|----------------------------------------------------|

|   | iii. |     Prepare      and maintain Trial Master File |
|--------|------|---------------------------------------------------------------------|

|   | iv. |     Prepare      Investigator Study File |
|--------|-----|--------------------------------------------------------------|

|   | v. |     Monitoring |
|--------|----|------------------------------------|

|   | vi. |     Enrollment      and follow-up of subjects |
|--------|-----|-------------------------------------------------------------------|

----

| SERVICE TO BE PROVIDED               |   | TOTAL COST(USD) |   |
|-----------------------------------------------------|--------|----------------------|--------|
| NON-CLINICAL      ACTIVITIES                        |   |                 |   |
| Document      translation and Informed Consent Form |   |                 |   |
| Local      Project Management                       |   |                 |   |
| Regulatory      activities                          |   |                 |   |
| Site      set up                                    |   |                 |   |
| IMP      management                                 |   |                 |   |
| Sample      management                              |   |                 |   |
| ECG      management                                 |   |                 |   |
| Sub-total                                           |   |                 | 0,00   |   |
| CLINICAL      ACTIVITIES                            |   |                 |   |   |
| Recruitment      activities                         |   |                 |   |   |
| Screening      period                               |   |                 |   |   |
| Medical      activities                             |   |                 |   |   |
| Laboratory      activities                          |   |                 |   |   |
| Treatment      period                               |   |                 |   |   |
| Medical      activities                             |   |                 |   |   |
| Laboratory      activities                          |   |                 |   |   |
| Follow-up      period                               |   |                 |   |   |
| Medical      activities                             |   |                 |   |   |
| Laboratory      activities                          |   |                 |   |   |
| Safety      management                              |   |                 |   |   |
| CRF      completion                                 |   |                 |   |   |
| Confinement                                         |   |                 |   |   |
| Fees/Compensation                                   |   |                 |   |   |
| Sub-total                                           |   |                 | 0,00   |   |
| LABORATORY      ACTIVITIES                          |   |                 |   |   |
| Laboratory      manual                              |   |                 |   |   |
| Datamanagement                                      |   |                 |   |   |
| Sample      management                              |   |                 |   |   |
| Others                                              |   |                 |   |   |
| Sub-total                                           |   |                 | 0,00   |   |
|                                                |   |                 |   |   |
| GRAND      TOTAL                                    |   |                 | 0,00   |   |

----

| SERVICE TO BE PROVIDED                    |   | RESPONSIBLE |   |   | HOURS  |   |   | HOURLY RATED(US) |   |   | TOTAL COST(USD) |   |
|----------------------------------------------------------|--------|-------------|--------|--------|--------|--------|--------|-----------------------|--------|--------|----------------------|--------|
| DOCUMENT      TRANSLATION AND INFORMED CONSENT           |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |
| Protocol      translation into Spanish                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |
| ICF      development & adaptation to different sites |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |
| Back      translation of ICF                             |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| LOCAL      PROJECT MANAGEMENT                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Start-up                                                 |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Protocol      review                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Project      plan preparation                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Weekly      teleconferences                              |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Investigator’s      Meeting attendance             |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Trial      Master File preparation                       |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Site      Investigator File preparation                  |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Preparation      of forms, spreadsheets, guidelines      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Phone      contact with the sites                        |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Ongoing                                                  |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Internal      meetings                                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Monthly      teleconferences                             |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Update      study plan                                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Update      Trial Master File                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Update      investigator Study File                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| SAE      notification to IRB/IEC/MOH                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Budget      administration and site payment              |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Prepare      monthly study reports                       |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Phone      contact with the sites                        |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Closure                                                  |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Complete      document collection from the sites         |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Trial      Master File preparation for archiving         |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Investigator      Study Files preparation for archiving  |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Final      payment to the sites                          |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Phone      contact with the sites                        |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| REGULATORY      ACTIVITIES                               |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Package      preparation for IRB                         |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| IRB      submission                                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| IRB      fees                                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Package      preparation for IEC                         |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| IEC      submission                                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| IEC      fees                                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Package      preparation for MOH                         |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| MOH      submission                                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| MOH      fees                                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Follow-up      of Submissions                            |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Respond      questions from IRB/IEC/MOH                  |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Prepare      reports to IRB/IEC/MOH                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| SITE      SET-UP                                         |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Prepare      contract with investigators                 |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Negotiate      contract and budget                       |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Initial      protocol training                           |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| IMP      MANAGEMENT                                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |
| Importation      paperwork preparation                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Importation      fees                                    |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Transfer      from customs to warehouse                  |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| IMP      destruction (paperwork + destruction)           |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| SAMPLE      MANAGEMENT                                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Exportation      paperwork preparation                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Exportation      fees                                    |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Transfer      from the sites to central lab              |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| ECG      MANAGEMENT                                      |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Importation      paperwork preparation                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Importation      fees                                    |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Return      to eRT at the end of the trial               |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                                |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                                     |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   |   |   |
| SUB-TOTAL      NON-CLINICAL ACTIVITIES                   |   |        |   |   |   |   |   |                  |   |   |                 |   |   |   | 0,00 |   |

----

|                                                                         |   |            |   |   |         |   |   | UNIT COST |   |   | TOTAL COST |   |
|------------------------------------------------------------------------------|--------|-----------------|--------|--------|--------------|--------|--------|----------------|--------|--------|-----------------|--------|
| SERVICE TO BE PROVIDED                                        |   | # PATIENTS |   |   | # UNITS |   |   | (USD)          |   |   | (USD)           |   |
| RECRUITMENT      ACTIVITIES                                                  |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |
| Call      center organization                                                |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |
| Phone      calls (average, 2 phone calls per visit)                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| SCREENING      PERIOD                                                        |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Medical      activities                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Informed      consent /      Demographics / Medical History      / |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Complete      Medical Examination / Height & Weight /                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Concomitant      Medication / Incl & Excl criteria                       |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| ECG                                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Laboratory      activities                                                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Routine      laboratory: Hematology, Chemistry, Urinalysis                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| HAV      Ab; HBsAg; HCV Ab                                                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| CD4                                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| HIV-RNA                                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Pregnancy      test (serum)                                                  |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Alcohol      test                                                            |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Urine      drug screen                                                       |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| VAT      (24%)                                                               |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| TREATMENT      PERIOD                                                        |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Medical      activities                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Targeted      physical examination                                           |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Vital      signs                                                             |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Adverse      Events, Concomitant medication, Dosing, Drugaccountability      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| ECG                                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Laboratory      activities                                                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Routine      laboratory Hematology, Chemistry                                |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Urinalysis                                                                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Urine      pregnancy test                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| CD4                                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| HIV-RNA                                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Blood      sampling, handling and storage                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| VAT      (24%)                                                               |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| FOLLOW-UP      PERIOD                                                        |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Medical      activities                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Targeted      physical examination                                           |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Vital      signs                                                             |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Adverse      Events, Concomitant medication                                  |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| ECG                                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Laboratory      activities                                                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Routine      laboratory: Hematology, Chemistry                               |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Urinalysis                                                                   |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Urine      pregnancy test                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| HIV-RNA                                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| CD4                                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Blood      sampling, handing and storage                                     |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| VAT      (24%)                                                               |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| SAFETY      MANAGEMENT                                                       |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Complete      SAE reports (initial)                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Complete      SAE reports (follow-up)                                        |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| CRF      COMPLETION                                                          |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Complete      CRF pages                                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Respond      queries                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| CONFINEMENT                                                                  |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Clinical      bed                                                            |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Linen      & food                                                        |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Travel      (from and to the Unit)                                           |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Coordinator      activities                                                  |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| FEES      / COMPENSATION                                                     |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Physician’s      fees                                                  |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Patient      compensation (screening)                                        |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Patient      compensation (enrolled)                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| Sub-total                                                                    |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |
|                                                                         |   |            |   |   |         |   |   |           |   |   |            |   |   |   |   |   |
| SUB-TOTAL CLINICAL      ACTIVITIES                                      |   |            |   |   |         |   |   |           |   |   |            |   |   |   | 0,00 |   |

----

| SERVICE TO BE PROVIDED         |   | RESPONSIBLE |   |   | HOURS /UNITS |   |   | HOURLY RATE(USD) |   |   | TOTAL COST(USD) |   |
|-----------------------------------------------|--------|-------------|--------|--------|-------------------|--------|--------|-----------------------|--------|--------|----------------------|--------|
| LABORATORY      MANUAL                        |   |        |   |   |              |   |   |                  |   |   |                 |   |
| Development      (including two revisions)    |   |        |   |   |              |   |   |                  |   |   |                 |   |
| Translation      into Spanish                 |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |
| Distribution      to sites                    |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |
| VAT      (24%)                                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| DATAMANAGEMENT                                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Database      development                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Phone      calls to request database upload   |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| VAT      (24%)                                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| SAMPLE      MANAGEMENT                        |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Safety      kits                              |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Materials      (tubes, pipettes, boxes, LRFs) |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Kit      preparation                          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Kit      distribution to sites                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Samples      sent to central lab              |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| PK      kits                                  |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Materials      (tubes. pipettes, boxes, LRFs) |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Kit      preparation                          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Kit      distribution to sites                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Samples      sent to central lab              |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Preparation      of samples to XXXXXXX        |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Preparation      of samples to NNNNNNN        |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| VAT      (24%)                                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| OTHERS                                        |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Breath      air alcohol measurement kit       |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Strips      to urine pregnancy test           |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Strips      to urine drug detection           |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| VAT      (24%)                                |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| Sub-total                                     |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   | 0,00 |   |
|                                          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   |   |   |
| SUB-TOTAL      LABORATORY ACTIVITIES          |   |        |   |   |              |   |   |                  |   |   |                 |   |   |   | 0,00 |   |

| PROJECT MILESTONE       |         | AMOUNT DUE(USD) |
|------------------------------|--------------|----------------------|
| Contract      execution      |         | GGGG,00              |
| MOH      approval            |         | GGGG,00              |
| First      patient enrolled  |         | GGGG,00              |
| Second      cohort completed |         | GGGG,00              |
| Last      patient completed  |         | GGGG,00              |
| Last      query responded    |         | GGGG,00              |
| GRAND      TOTAL             |    | TTTTTTT,00           |

----

| IDENIX      PHARMACEUTICALS, Inc |               | ACLIRES      International, Ltd. |
|----------------------------------|--------------------|----------------------------------|
|                             |               |                             |
|                             |               |                             |
| Signature:                       |     |                             | Signature: |     |
|                             |               |                             |
| Name:                            |     |                             | Name: |     |
|                             |               |                             |
| Title:                           |     |                             | Title: |     |
|                             |               |                             |
| Date:                            |     |                             | Date: |     |

----

| Sponsor:                |   |   |
|-------------------------|--------|--------|
|                    |   |   |
| Sponsor      Study No.: |   |   |
|                    |   |   |
| ACLIRES      Argentina  |   |   |
| Study      No.:         |   |   |

|                   |                                                       | Responsibility |   |   | Date    |   |
|------------------------|------------------------------------------------------------|----------------|--------|--------|---------|--------|
| Tasks                  |                                                       | Sponsor        |   |   | ACLIRES |   |   | (planned) |   |   | (actual) |   |
| Study      Preparation |                                                       |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Study      Synopsis or Outline                             |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Preparation      of Financial Agreement                    |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Study      Protocol                                        |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | CRF      Preparation                                       |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | CRF      Review                                            |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Audit      of the Protocol and CRFs                        |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Informed      Consent Form                                 |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Submission      to Ethics Committees                       |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Subjects      Insurance                                    |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Submission      to MOH (ANMAT)                             |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Import      of study drug                                  |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Packaging      and/or Labeling of Study Drug               |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Resourcing      of registered Study Medication (if needed) |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Resourcing      of Lab. Material                           |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                 | Randomization      Schedule                                |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |

----

|                                        |                                     | Responsibility |   |   | Date    |   |
|---------------------------------------------|------------------------------------------|----------------|--------|--------|---------|--------|
| Tasks                                       |                                     | Sponsor        |   |   | ACLIRES |   |   | (planned) |   |   | (actual) |   |
| Study      Conduct                          |                                     |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Safety      Laboratory                   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Pharmacokinetic      Assays              |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Pharmacodynamic      Assays              |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Shipment      for PK / PD Samples        |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Monitoring                               |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Site      Initiation                     |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Site      Close-out                      |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Reporting      of SAEs to Authorities    |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Preparation      of Amendments           |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | On      Site Audit                       |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| Data Management / Statistical      Analysis |                                     |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Statistical      Analysis Plan           |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Coding      of AEs, cone. Therapies etc. |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Data      Entry                          |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Database      Validation                 |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Database      review prior to lock       |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Database      Log                        |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Data      Transfer                       |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Statistical      Analysis                |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | PK-Analysis                              |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Statistical      Report                  |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·                                      | Bioanalytical      Report                |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |

----

|                 |                                     | Responsibility |   |   | Date    |   |
|----------------------|------------------------------------------|----------------|--------|--------|---------|--------|
| Tasks                |                                     | Sponsor        |   |   | ACLIRES |   |   | (planned) |   |   | (actual) |   |
| Study      Close Out |                                     |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Safety      Summary                      |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Integrated      Clinical Report          |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Audit      of Integrated Clinical Report |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Drug      Accountability                 |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Return      of Study Drug                |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Archiving      of Study Documents        |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |
| ·               | Shipment      Costs for CRFs             |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |   |

|                                                                                  |   | Responsibility |   |   | Date    |   |
|---------------------------------------------------------------------------------------|--------|----------------|--------|--------|---------|--------|
| Tasks                                                                                 |   | Sponsor        |   |   | ACLIRES |   |   | (planned) |   |   | (actual) |   |
| Others                                                                                |   |           |   |   |    |   |   |   |   |   |   |   |
|                                                                                  |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
| Development      of Emergency Envelopes (patient specific) and delivery to      site. |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
|                                                                                  |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
| Certificate      of Analysis and GMP certificate                                      |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
|                                                                                  |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
|                                                                                  |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |
|                                                                                  |   |           |   |   |    |   |   |   |   |   |   |   |   |   |   |   |

----