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SearchRemoveBill and Melinda Gates Fndn.filterFilter Results by CategoryFilter Results by CommodityFilter Results by Funding SourceSort by: Relevance (Most - Least)
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      to advance O-antigen-based Shigella vaccines through to licensure by providing the critical data on immunogenicity linked to efficacy required for immuno-bridgingÂ
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2018
          End date
              2020
          to advance O-antigen-based Shigella vaccines through to licensure by providing the critical data on immunogenicity linked to efficacy required for immunobridgingÂ
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2018
          End date
              2019
          to complete the laboratory development of the remaining two components of a new Shigella 4-valent Synthetic Conjugate Vaccine to prevent Shigella diarrhea and dysentery among children in LMICs.
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2018
          End date
              2020
          to generate immunological target values that new vaccines against Shigella, a major cause of moderate and severe diarrhea globally, need to meet to advance along the clinical development pipeline.Â
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2018
          End date
              2018
          to develop a new medicine for the treatment of children and adults with diarrhea caused by Cryptosporidium
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2019
          to improve our understanding rotaviral evolution and the genetic diversity of the wildtype virus population, aspects critical for the ongoing development and success of rotavirus vaccine programs
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2021
          to generate immunogenicity and safety data on the BBIL rotavirus vaccine, ROTAVAC and ROTAVAC 5C, in one African country, which will support WHO SAGE policy recommendations and country-level decision-making on potential use of these vaccines
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2020
          to determine the optimal characteristics for a new drug to combat Cryptospodioisis, an infectious parasitic disease that is a major cause of diarrhea and related chronic health problems in children worldwideÂ
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2019
          to generate evidence quantifying the causal role of aflatoxin ingestion on post-natal growth
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2022
          to stimulate the development of a new therapeutic for cryptosporidium
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to establish a national surveillance system for enteric fever in India
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2019
          to estimate the burden and severity of invasive Salmonella infections in Moshi, Tanzania
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to support late preclinical and early clinical development of a novel treatment for cryptosporidiosis
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to evaluate effectiveness and impact of typhoid conjugate vaccine introduction program in Navi Mumbai, India
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2019
          to identify natural compounds in human milk that protect infants from environmental enteric disease and diarrhea
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2019
          to identify the transmission patterns of Cryptosporidium, a leading cause of diarrhea in young children, in Bangladesh
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2015
          End date
              2017
          to compare the virulence of wild type S. Typhi with that of a toxin-defective mutant in a human volunteer model of S. Typhi infection
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2015
          End date
              2017
          to evaluate the performance of typhoid diagnostics in a confined population, during an outbreak of typhoid in Zomba and Malosa, Malawi.
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to determine if an approved drug product for another indication will demonstrate efficacy in humans to treat diarrhea caused by Cryptospordidium
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2017
          End date
              2019
          to understand typhoid transmission dynamics in a highly endemic setting in Kenya, thereby informing effective prevention strategies, including vaccination
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to determine the prevalence of cryptosporidium infection among adults with HIV infection using a rapid diagnostic stool test in order to design a therapeutic intervention study
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to complete a study and publication on the evidence for the currently used definition of diarrhea, as well as systematic reviews related to dehydration and Shigella indications
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2015
          End date
              2017
          to develop methods to identify environmental reservoirs of S. Typhi, and use these findings to inform targeted intervention strategies for typhoid fever through spatial modeling
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to engineer a live vaccine delivery platform that can be given by oral administration to reduce the global diarrheal burden in young children due to infections by enteric pathogens
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
          to determine if vaccination can reduce Campylobacter infection and environmental enteric dysfunction (EED), thereby improving gut health while increasing infant growth trajectories
    

  Funding Source
          Bill and Melinda Gates Fndn.
          Start date
              2016
          End date
              2018
  
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