EX-4.3





 Exhibit 4.3 

FIFTEENTH SUPPLEMENTAL INDENTURE, (this “Supplemental Indenture”) dated as of March 27, 2020, by and among CHS/Community
Health Systems, Inc., a Delaware corporation (“Issuer”), the party that is a signatory hereto as a Guarantor (the “Guaranteeing Subsidiary”) and Regions Bank, as Trustee under the Indenture referred to below. 

W I T N E S S E T H: 

WHEREAS, each of the Issuer, the Guarantors and the Trustee have heretofore executed and delivered an indenture dated as of January 27,
2014 (as amended, supplemented, waived or otherwise modified, the “Indenture”), providing for the issuance on such date of an aggregate principal amount of $3,000,000,000 of 6.875% Senior Notes due 2022 (the
“Notes”) of the Issuer; 
 WHEREAS, the Indenture provides that the Guaranteeing Subsidiary shall execute and deliver to
the Trustee a supplemental indenture pursuant to which the Guaranteeing Subsidiary shall unconditionally guarantee all of the Issuer’s Obligations under the Notes and the Indenture on the terms and conditions set forth herein and under the
Indenture (the “Note Guarantee”), each on the terms and conditions set forth herein; and 
 WHEREAS, pursuant to
Section 9.1 of the Indenture, the Issuer, any Guarantor and the Trustee are authorized to execute and deliver this Supplemental Indenture to amend or supplement the Indenture, without the consent of any Holder; 

NOW, THEREFORE, in consideration of the foregoing and for other good and valuable consideration, the receipt of which is hereby acknowledged,
the Issuer, the Guaranteeing Subsidiary and the Trustee mutually covenant and agree for the benefit of the Trustee and the Holders of the Notes as follows: 

ARTICLE I 

DEFINITIONS 
 SECTION 1.1.
Defined Terms. As used in this Supplemental Indenture, terms defined in the Indenture or in the preamble or recitals hereto are used herein as therein defined. The words “herein,” “hereof” and “hereby” and other
words of similar import used in this Supplemental Indenture refer to this Supplemental Indenture as a whole and not to any particular section hereof. 

ARTICLE II 

AGREEMENT TO BE BOUND; GUARANTEE 

SECTION 2.1.  Agreement to be Bound. The Guaranteeing Subsidiary hereby becomes a party to the Indenture as a
“Guarantor” and as such will have all of the rights and be subject to all of the obligations and agreements of a “Guarantor” under the Indenture. 

SECTION 2.2.  Guarantee. The Guaranteeing Subsidiary agrees, on a joint and several basis with all the existing Guarantors,
to fully, unconditionally and irrevocably Guarantee to each Holder of the Notes and the Trustee the Guaranteed Obligations pursuant to Article X of the Indenture as and to the extent provided for therein. 

  
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 ARTICLE III 

MISCELLANEOUS 
 SECTION
3.1.  Notices. All notices and other communications to the Guarantors shall be given as provided in the Indenture. 

SECTION 3.2.  Merger and Consolidation. The Guaranteeing Subsidiary shall not sell or otherwise dispose of all or
substantially all of its assets to, or consolidate with or merge with or into, another Person (other than the Issuer or any Restricted Subsidiary that is a Guarantor or becomes a Guarantor concurrently with the transaction) except in accordance with
Section 4.1(e) of the Indenture. 
 SECTION 3.3.  Release of Guarantee. The Note Guarantees
hereunder may be released in accordance with Section 10.2 of the Indenture. 
 SECTION
3.4.  Parties. Nothing expressed or mentioned herein is intended or shall be construed to give any Person, firm or corporation, other than the Holders and the Trustee, any legal or equitable right, remedy or claim under or in
respect of this Supplemental Indenture or the Indenture or any provision herein or therein contained. 
 SECTION
3.5.  Governing Law. This Supplemental Indenture shall be governed by, and construed in accordance with, the laws of the State of New York. 

SECTION 3.6.  Severability. In case any provision in this Supplemental Indenture shall be invalid, illegal or unenforceable,
the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby and such provision shall be ineffective only to the extent of such invalidity, illegality or unenforceability. 

SECTION 3.7.  Benefits Acknowledged. The Guaranteeing Subsidiary’s Note Guarantee is subject to the terms and
conditions set forth in the Indenture. The Guaranteeing Subsidiary acknowledges that it will receive direct and indirect benefits from the financing arrangements contemplated by the Indenture and this Supplemental Indenture and that the guarantee
and waivers made by it pursuant to its Note Guarantee are knowingly made in contemplation of such benefits. 
 SECTION
3.8.  Ratification of Indenture; Supplemental Indentures Part of Indenture. Except as expressly amended hereby, the Indenture is in all respects ratified and confirmed and all the terms, conditions and provisions thereof shall
remain in full force and effect. This Supplemental Indenture shall form a part of the Indenture for all purposes, and every Holder of Notes heretofore or hereafter authenticated and delivered shall be bound hereby. 

SECTION 3.9.  The Trustee. The Trustee makes no representation or warranty as to the validity or sufficiency of this
Supplemental Indenture or with respect to the recitals contained herein, all of which recitals are made solely by the other parties hereto. 

SECTION 3.10.  Counterparts. The parties hereto may sign any number of copies of this Supplemental Indenture. Each signed
copy shall be an original, but all of them together represent the same agreement. The exchange of copies of this Supplemental Indenture and of 

  
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signature pages by facsimile or other electronic transmission shall constitute effective execution and delivery of this Supplemental Indenture as to the parties hereto and may be used in lieu of
the original Supplemental Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile or other electronic transmission shall be deemed to be their original signatures for all purposes. 

SECTION 3.11.  Execution and Delivery. The Guaranteeing Subsidiary agrees that its Note Guarantee shall remain in full force
and effect notwithstanding any absence on each Note of a notation of any such Note Guarantee. 
 SECTION 3.12.  Headings.
The headings of the Articles and the Sections in this Supplemental Indenture are for convenience of reference only and shall not be deemed to alter or affect the meaning or interpretation of any provisions hereof. 

[Signature page follows] 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed as of the date first above written. 
  

			
	GREENBRIER VMC, LLC,
		 	  a Delaware limited liability company
		
	By:	 	  /s/ R. Gabriel Ottinger                        
		 	R. Gabriel Ottinger
		 	Senior Vice President and Treasurer
	
	Acting on behalf of the Guaranteeing Subsidiary set forth above


  

			
	Acknowledged by:
	
	CHS/COMMUNITY HEALTH SYSTEMS, INC.


			
		
	By:	 	  /s/ R. Gabriel Ottinger                      
		 	R. Gabriel Ottinger
		 	Senior Vice President and Treasurer


  
 [Signature Page to
Fifteenth Supplemental Indenture (2022 Notes)] 













 
			
	REGIONS BANK,
	as Trustee
		
	By:	 	   /s/ Kristine Prall

		 	  Kristine Prall
		 	  Vice President



  
 [Signature Page to
Fifteenth Supplemental Indenture (2022 Notes)]