Exhibit 31
          CERTIFICATION OF CHIEF EXECUTIVE OFFICER AND CHIEF FINANCIAL
                                    OFFICER

I, C.E. "Rick" Strattan, certify that:

1.   I have reviewed this Quarterly Report (Form 10-Q) of CTD Holdings, Inc.;

     2. Based on my knowledge, this report does not contain any untrue statement
of a  material  fact or omit to  state a  material  fact  necessary  to make the
statements made, in light of the circumstances  under which such statements were
made, not misleading with respect to the period covered by this report;

     3. Based on my knowledge,  the financial  statements,  and other  financial
information included in this report, fairly present in all material respects the
financial  condition,  results of operations and cash flows of the registrant as
of, and for, the periods presented in this report;

     4. I am responsible for  establishing and maintaining  disclosure  controls
and  procedures  (as defined in Exchange Act Rules  13a-15(e) and 15d-15(e)) and
internal  controls  over  financial  reporting (as defined in Exchange Act Rules
13a-15(f) and 15d-15(f)) for the registrant and have:

          a. Designed such disclosure  controls and  procedures,  or caused such
          disclosure   controls  and   procedures   to  be  designed   under  my
          supervision,  to ensure  that  material  information  relating  to the
          registrant,  including its consolidated subsidiaries, is made known to
          me by others within those entities,  particularly during the period in
          which this report is being prepared;

          b. Designed such internal control over financial reporting,  or caused
          such internal  control over  financial  reporting to be designed under
          our  supervision,   to  provide  reasonable  assurance  regarding  the
          reliability  of financial  reporting and the  preparation of financial
          statements for external purposes in accordance with generally accepted
          accounting principles;

          c. Evaluated the effectiveness of the registrant's disclosure controls
          and procedures  and presented in this report my conclusions  about the
          effectiveness of the disclosure controls and procedures, as of the end
          of the period covered by this report based on such evaluation; and

          d.  Disclosed in this report any change in the  registrant's  internal
          control over financial reporting that occurred during the registrant's
          most recent fiscal quarter (the registrant's  fourth fiscal quarter in
          the case of an annual  report)  that has  materially  affected,  or is
          reasonably  likely to materially  affect,  the  registrant's  internal
          control over financial reporting; and

5. I have disclosed, based on my most recent evaluation of internal control over
financial reporting, to the registrant's auditors and the audit committee of the
registrant's   board  of  directors  (or  persons   performing   the  equivalent
functions):

          a. All significant  deficiencies and material weaknesses in the design
          or operation of internal  control over financial  reporting  which are
          reasonably  likely to  adversely  affect the  registrant's  ability to
          record, process, summarize and report financial information; and

          b. Any fraud,  whether or not material,  that  involves  management or
          other  employees  who  have a  significant  role  in the  registrant's
          internal control over financial reporting.

Date:  May ___, 2010


__________________________________
C.E. "Rick" StrattAn
Chief Executive Officer
Chief Financial Officer