EX-4.1




 Exhibit 4.1 

Confidential 

REGISTRATION RIGHTS AGREEMENT 

THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of December 1, 2021, is made by and between Twist
Bioscience Corporation, a Delaware corporation (“Parent”), Edgemont Capital Partners, L.P. (“Edgemont”) and each Holder set forth on the signature pages hereto (or who delivers an executed joinder to this agreement
in the form of Exhibit A). 
 WHEREAS, Parent, Nautilus Acquisition Sub, Inc., a Delaware corporation, AbX Biologics, Inc. (d/b/a
Abveris), a Delaware corporation (the “Company”), and the Securityholder Representative have entered into an Agreement and Plan of Merger and Reorganization, dated as of November 19, 2021 (together with all schedules and
exhibits thereto, the “Merger Agreement”), pursuant to which Parent will through the Merger acquire the Company (together with the other transactions contemplated by the Merger Agreement, the “Transactions”). 

WHEREAS, as a result of the Merger, at the Effective Time, all of the capital stock of the Company will be cancelled and terminated and
converted into the right to receive the consideration set forth in the Merger Agreement. 
 WHEREAS, in connection with the Transactions,
Edgemont, the Company, Parent and the other parties thereto have entered into that certain Termination Agreement (the “Edgemont Side Letter”), whereby Edgemont has agreed to accept its fee or other amounts in cash and shares of
Parent Common Stock; 
 WHEREAS, as a condition and inducement to the willingness of the Company to enter into the Merger Agreement, the
Company has required that Parent enter into this Agreement. 
 WHEREAS, in order to induce the Company to consummate the Merger and the
other Transactions, Parent is willing to enter into this Agreement. 
 AGREEMENT 

NOW, THEREFORE, in consideration of the mutual covenants contained herein and other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto agree as follows effective at, and is contingent upon the consummation of, the Effective Time: 

1. Definitions. All capitalized terms that are used but not defined herein shall have the respective meanings ascribed to them in the
Merger Agreement. For all purposes of and under this Agreement, the following capitalized terms shall have the respective meanings below: 

(a) “Contingent Shares” means the Parent Common Stock issued as Contingent Consideration. 

(b) “Exchange Act” means the Securities Exchange Act of 1934, as amended. 

(c) “Form S-3” means a registration statement on Form
S-3 promulgated by the SEC under the Securities Act, as such form is in effect on the date hereof, or any successor or replacement form of registration statement promulgated by the SEC under the Securities Act
from and after the date hereof, in any such case which similarly permits inclusion or incorporation of substantial information by reference to other documents filed by Parent with the SEC. 











 (d) “Holder” means a Securityholder to whom shares of Parent Common Stock
are issued in connection with the Merger pursuant to the Merger Agreement, Edgemont (or if directed by Edgemont pursuant to the Edgemont Side Letter, David Blume and/or Jeff Swearingen; provided that each such individual executes and delivers a
Joinder Agreement in the form attached hereto as Exhibit A prior to the issuance of Parent Common Stock to either of them) or a transferee to whom registration rights granted under this Agreement are assigned pursuant to
Section 6 hereof. 
 (e) “Lock-up Period” means, with
respect to the Lock-up Securities, the period beginning on the date that the Registration Statement is filed with the SEC pursuant to Section 2(a) and ending on the twenty-first (21st) day thereafter; provided, that (i) forty percent (40%) of such Lock-up Securities shall be released on each of the seventh (7th) and the fourteenth (14th) day following such filing and (ii) the remaining twenty percent (20%) shall be released on the twenty-first (21st) day following such filing. 
 (f)
“Lock-up Securities” means fifty percent (50%) of the Subject Securities of each Holder, excluding the Contingent Shares. 

(g) “Registrable Securities” means, (i) for each Holder, its Subject Securities, and (ii) for all Holders, the sum
of the Subject Securities held by them as a group; provided, however, that the Subject Securities held by a particular Holder shall cease to be Registrable Securities (x) after the Registration Statement with respect to the sale
of such securities shall have been declared effective under the Securities Act and such securities shall have been disposed of in accordance with the Registration Statement and with Section 2 hereof, or (y) at such
time as such Holder is eligible to sell such securities in compliance with Rule 144 promulgated by the SEC under the Securities Act without any limitation as to volume or manner of sale. 

(h) “Securities Act” means the Securities Act of 1933, as amended. 

(i) “SEC” means the United States Securities and Exchange Commission. 

(j) “Subject Securities” means (i) for each Holder (except Edgemont), the number of shares of Parent Common Stock
issuable to such Holder in the Merger at the Effective Time pursuant to the Merger Agreement (including any shares of Parent Common Stock subject to the Employee Vesting Agreements, but excluding any shares of Parent Common Stock issued after the
date the Registration Statement is filed with the SEC, other than the Contingent Shares), (ii) the Contingent Shares, (iii) for Edgemont, the number of shares of Parent Common Stock issuable to Edgemont pursuant to the Edgemont Side Letter and
(iv) any securities issued as (or issuable upon the conversion, exercise or exchange of any warrant, right or other security that is issued as) a dividend, stock split, combination or any reclassification, recapitalization, merger,
consolidation, exchange or any other distribution or reorganization with respect to, or in exchange for, or in replacement of, the securities referenced in clauses (i)—(iii) above. 

2. Registration of Offers and Sales of Registrable Securities. 

(a) No later than the tenth (10th) day following the Closing, Parent shall file with the
SEC (i) a registration statement (together with the related prospectus, amendments and supplements to such registration statement, and including pre- and post-effective amendments, and all exhibits and
material incorporated by reference in such registration statement, the “New Registration Statement”) on Form S-3 covering the resale of all Registrable Securities or (ii) if a
registration statement covering the resale of all Registrable Securities is effective and available at such time, a prospectus supplement and any related filings pursuant to the Securities Act and Exchange Act (together with the New Registration
Statement, each, as applicable, the “Registration Statement”), provided, however, that, Parent’s obligation to include 

  
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the Registrable Securities of any particular Holder in the Registration Statement shall be expressly conditioned upon (A) Parent’s prior receipt of all information and materials
regarding such Holder as specified in Section 7, (B) delivery by such Holder of a joinder to this Agreement in the form of Exhibit A hereto, and (C) the taking of all other action required to be taken by such
Holder under this Agreement. 
 (b) Notwithstanding Section 2(a), (i)(A) in the event that the filing deadline
contemplated by Section 2(a) shall occur during a trading “blackout” period under Parent’s securities trading policies (such “blackout” periods beginning two (2) weeks before the end of each
fiscal quarter and ending two (2) Business Days after the release of Parent’s quarterly financials), then Parent shall not be required to file the Registration Statement contemplated by Section 2(a) until such
“blackout” period is no longer applicable, (B) Parent shall not be required to file the Registration Statement contemplated by Section 2(a) if Parent, in its reasonable good faith judgment (after consultation with
counsel), has determined that the offer and sale or other disposition of Registrable Securities pursuant to the Registration Statement would require public disclosure by Parent of material nonpublic information that Parent is not otherwise obligated
to disclose and (C) Parent shall not be deemed to have breached its obligations hereunder if Parent shall fail to fulfill its obligations under Section 2(a) at a time when sales of Parent Common Stock have been suspended
globally under Parent’s then effective registration statements or during times when new registration statements are not permitted to be filed under SEC rules, provided, that if Parent delays the filing of the Registration Statement
pursuant to this Section 2(b)(A), Parent shall file such Registration Statement as soon as reasonably practicable following the lapsing or expiration of the circumstances that led Parent to delay such filing; and (ii) in the event that
Parent has not received the consent of its independent registered public accounting firm or other required consents from auditors to include such firm’s audit report in the Registration Statement, then Parent shall not be required to file the
Registration Statement contemplated by Section 2(a) until Parent shall have received such consents, provided, that (x) Parent has used commercially reasonable efforts to obtain such consents, and (y) Parent
shall file such Registration Statement as soon as reasonably practicable following the receipt of such consent. 
 (c) Parent shall use its
commercially reasonable efforts to: 
 (i) to the extent that the Registration Statement is not automatically effective upon filing with the
SEC, cause the Registration Statement to be declared effective as promptly as reasonably practicable after the filing thereof with the SEC (and shall request acceleration of effectiveness of the Registration Statement by the SEC no later than the
end of the fifth (5th) Business Day after receiving notice from the SEC that it will not review the Registration Statement or that any SEC comments have been resolved to the satisfaction of the
SEC), and keep the Registration Statement continuously effective until the earlier to occur of (A) the date on which all Registrable Securities included in the Registration Statement have been sold, and (B) the six (6)-month anniversary of
the later to occur of (x) the Closing Date and (y) the earlier to occur of (1) the date it is determined that the 2022 Revenue Target will not be achieved and (2) achievement of the 2022 Revenue Target, to the extent achieved
(such earlier date, the “Registration Termination Date”); provided, however, that the Registration Termination Date with respect to Registrable Securities issued to Edgemont shall be the earlier to occur of
(A) the date on which all such Registrable Securities included in the Registration Statement have been sold, and (B) the six (6)-month anniversary of the Closing Date; 

(ii) prepare and file with the SEC such amendments to the Registration Statement and amendments or supplements to the prospectus used in
connection therewith as may be necessary to keep such Registration Statement continuously available and to comply with the provisions of the Securities Act with respect to the sale or other disposition of all Registrable Securities included in the
Registration Statement; 

  
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 (iii) furnish to each Holder such number of copies of any prospectus (including any
preliminary prospectus and any amended or supplemented prospectus) in conformity with the requirements of the Securities Act as each Holder may reasonably request in order to effect the offering and sale of the Registrable Securities to be offered
and sold by such Holder thereunder, but only while Parent shall be required under the provisions hereof to cause the Registration Statement to remain effective; 

(iv) register or qualify the Registrable Securities covered by the Registration Statement under the securities or blue sky laws of such
jurisdictions as each Holder shall reasonably request and keep each such registration or qualification effective until the Registration Termination Date; provided, however, that Parent shall not be required in connection therewith or as a
condition thereto to qualify to do business or to file a general consent to service of process in any such jurisdiction where it has not been qualified or is not otherwise subject to a general consent for service of process; and 

(v) notify the Holders, promptly after it shall receive notice thereof, of the date and time the Registration Statement and each
post-effective amendment thereto shall have become or been declared effective or an amendment or supplement to any prospectus forming a part of the Registration Statement shall have been filed with the SEC. 

3. Suspension of Offers and Sales of Registrable Securities under Registration Statement. At any time from and after the effective date
of the Registration Statement, Parent may restrict offers and sales or other dispositions of Registrable Securities under the Registration Statement, and a Holder will not be able to offer or sell or otherwise dispose of Registrable Securities
thereunder, by delivering a written notice (a “Suspension Notice”) to all Holders of Registrable Securities pursuant to Section 9 signed by an authorized representative of Parent stating that a delay in the
offer and sale or other disposition of Registrable Securities is necessary because Parent, in its reasonable good faith judgment, has determined that the offer and sale or other disposition of Registrable Securities would require public disclosure
by Parent of material non-public information that is not included in the Registration Statement and that the immediate disclosure of such information would be detrimental to Parent; provided, however,
Parent may not suspend offers and sales or other dispositions of Registrable Securities pursuant to this Section 3 for more than ninety (90) days in the aggregate. Promptly following the cessation or discontinuance of
the facts and circumstances forming the basis for any Suspension Notice, Parent shall use its commercially reasonable efforts to amend the Registration Statement and/or amend or supplement the related prospectus included therein to the extent
necessary, and take all other actions reasonably necessary, to allow the offer and sale or other disposition of Registrable Securities to recommence as promptly as possible, and promptly notify all Holders of Registrable Securities in writing when
such offers and sales or other dispositions of Registrable Securities under the Registration Statement may recommence. Upon receipt of a Suspension Notice, Holders shall immediately suspend their use of the Registration Statement and any prospectus
included therein or forming a part thereof to offer and sell or otherwise dispose of Registrable Securities, and shall not offer or sell or otherwise dispose of Registrable Securities under the Registration Statement or any prospectus included
therein or forming a part thereof until receipt of a notice from Parent pursuant to the preceding sentence that offers and sales or other dispositions of Registrable Securities may recommence. Holders shall keep the fact that Parent has delivered a
Suspension Notice and any non-public information provided by Parent in connection therewith confidential, shall not disclose or reveal the Suspension Notice or any such information to any person or entity and
shall not use such information for securities trading or any other purpose. 

  
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 4. Fees and Expenses. All of the out-of-pocket expenses incurred in connection with any registration of Registrable Securities pursuant to this Agreement, including all SEC fees, blue sky registration and filing fees, Nasdaq Stock Market
notices and filing fees, printing fees and expenses, transfer agents’ and registrars’ fees and expenses and all reasonable fees and expenses of Parent’s outside counsel and independent accountants shall be paid by Parent. Parent shall
not be responsible for any legal fees for any Holder or any selling expenses of any Holder (including any broker’s fees or commissions). 

5. Indemnification. 
 (a)
To the extent permitted by law, Parent shall indemnify and hold harmless each Holder, each of its directors, officers and employees, each person controlling such Holder within the meaning of Section 15 of the Securities Act, and such
Holder’s legal counsel and independent accountants (each, a “Seller Indemnified Party”), with respect to which registration, qualification or compliance has been effected pursuant to this Agreement, from and against all losses,
damages and liabilities (or actions in respect thereof), including any of the foregoing incurred in settlement of any litigation, commenced or threatened, arising out of or based on any untrue statement (or alleged untrue statement) of a material
fact contained in the Registration Statement, the prospectus forming a part thereof or included therein, and any amendment or supplement thereto, incident to any such registration, qualification or compliance, or based on any omission (or alleged
omission) to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading, or any violation by Parent of any rule or regulation promulgated under the Securities Act, the Exchange Act or state
securities laws applicable to Parent in connection with any such registration, qualification or compliance, and Parent shall reimburse each Seller Indemnified Party for any legal and any other expenses reasonably incurred by them, as such expenses
are incurred, in connection with investigating, preparing or defending any lawsuit, claim or action relating thereto; provided, however, that Parent shall not be required to indemnify, or otherwise be liable to, any Seller Indemnified
Party to the extent that any such loss, damage, liability or expense arises out of, or is based on, (i) any untrue statement or omission or alleged untrue statement or omission, made in reliance upon and in conformity with written information
furnished by or on behalf of any Seller Indemnified Party to Parent specifically for use therein, or (ii) the failure of any Seller Indemnified Party to comply with its covenants and agreements hereunder. 

(b) To the extent permitted by law, if Registrable Securities held by a Holder are included in the securities as to which such registration,
qualification or compliance is being effected, such Holder shall indemnify and hold harmless Parent, each of its directors, officers, employees and other agents and representatives, each person controlling Parent within the meaning of
Section 15 of the Securities Act, and Parent’s legal counsel and independent accountants, as well as each other Holder, each of such other Holder’s directors, officers, employees and other agents and representatives, each person
controlling such other Holder within the meaning of Section 15 of the Securities Act, and such other Holder’s legal counsel and independent accountants (each a “Parent Indemnified Party”), from and against all losses,
damages and liabilities (or actions in respect thereof) arising out of, or based on, any untrue statement (or alleged untrue statement) of a material fact contained in the Registration Statement, the prospectus forming a part thereof or included
therein, and any amendment or supplement thereto, incident to any such registration, qualification or compliance, or any omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the
statements therein not misleading, or any violation by such Holder of any rule or regulation promulgated under the Securities Act, the Exchange Act or state securities laws applicable to such Holder in connection with any such registration,
qualification or compliance, and such Holder shall reimburse each Parent Indemnified Party for any legal or any other expenses reasonably incurred by them, as such expenses are incurred, in connection with investigating or defending any such
lawsuit, claim or action relating thereto, in each case to the extent, but only to the extent, that such untrue statement (or alleged untrue statement) or omission (or alleged omission) is made in such registration statement, prospectus, offering
circular or other document in reliance upon and in conformity with written information furnished to Parent specifically for use therein. 

  
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 (c) Each party entitled to indemnification under this Section 5
(the “Indemnified Party”) shall give notice to the party required to provide indemnification (the “Indemnifying Party”) promptly after such Indemnified Party has written notice of any lawsuit, claim or action as to
which indemnity may be sought hereunder, and shall permit the Indemnifying Party to assume the defense of any such lawsuit, claim or action; provided, however, that counsel for the Indemnifying Party, who shall conduct the defense of such
claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld, delayed or conditioned), and the Indemnified Party may participate in such defense at such party’s expense, and
provided, further, that the failure of any Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Agreement except to the extent, but only to the extent, that the
Indemnifying Party’s ability to defend against such claim or litigation is materially and adversely impacted by the failure to give such notice. No Indemnifying Party, in the defense of any such lawsuit, claim or action shall, except with the
consent of each Indemnified Party, consent to entry of any judgment or enter any settlement which does not include as an unconditional term thereof the giving by the claimant or plaintiff to the Indemnified Party of a release from all liability in
respect to such lawsuit, claim or action. 
 (d) If the indemnification required by this Section 5 from the
Indemnifying Party is unavailable to or insufficient to hold harmless an Indemnified Party in respect of any indemnifiable losses, claims, damages, liabilities, or expenses, then the Indemnifying Party shall contribute to the amount paid or payable
by the Indemnified Party as a result of such losses, claims, damages, liabilities, or expenses in such proportion as is appropriate to reflect relative fault of the Indemnified and Indemnifying Parties, in connection with the actions which resulted
in such losses, claims, damages, liabilities, or expenses, as well as any other relevant equitable considerations. The relative fault of the Indemnifying Party and the Indemnified Party shall be determined by reference to, among other things,
whether any action in question, including any untrue or alleged untrue statement of a material fact, has been made by, or relates to information supplied by, such Indemnifying Party or Parties, and the parties’ relative intent, knowledge,
access to information, and opportunity to correct or prevent such action. The amount paid or payable by a party as a result of the losses, claims, damage, liabilities, and expenses referred to above shall be deemed to include any legal or other fees
or expenses reasonably incurred by such party in connection with any investigation or proceeding. Parent and the Holders agree that it would not be just and equitable if contribution pursuant to this Section 5(d) were
determined by pro rata allocation or by any other method of allocation which does not take account of the equitable considerations referred to in the prior provisions of this Section 5(d). 

(e) The obligations of Parent and each Holder under this Section 5 shall survive the completion of any offering and
sale or other disposition of Registrable Securities in the Registration Statement filed with the SEC pursuant to this Agreement until the expiration of any statute of limitations relating to the subject matter of this
Section 5. 
 6. Limitation on Assignment of Registration Rights. The rights of each Holder under this
Agreement may not be assigned by a Holder to any other Person unless such a transfer is pursuant to a transfer of Registrable Securities (i) by will or intestate succession, (ii) to a trust upon death, (iii) to an Affiliate or an
affiliated fund or entity of such Holder (provided that there is no change in beneficial ownership), which means with respect to a limited liability company or a limited liability partnership, a fund or entity managed by the same manager or managing
member or general partner or management company or by an entity controlling, controlled by, or under common control with such manager or managing member or general partner or management company or (iv) with the prior written consent of Parent.
Prior to a permitted transfer of rights under this Agreement (or, with respect to assignments contemplated by clauses (i) and (ii) of the prior sentence, within a reasonable time following such assignment), Holder must furnish Parent with
written notice of the name and address of such transferee and 

  
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the Registrable Securities with respect to which such registration rights are being assigned and a copy of a duly executed written instrument in form reasonably satisfactory to Parent by which
such transferee assumes all of the obligations and liabilities of its transferor hereunder and agrees itself to be bound hereby. No transfer of rights under this Agreement shall be permitted if, immediately following such transfer, the offer and
sale or other disposition of Registrable Securities by the transferee is not restricted under the Securities Act. 
 7. Information by
Holder. Any Holder of Registrable Securities to be included in the Registration Statement shall furnish to Parent such information regarding such Holder, the Registrable Securities held by such Holder and the offer and sale or other distribution
proposed by such Holder as Parent may reasonably request and as shall be required in connection with any registration, qualification or compliance contemplated by this Agreement (including, for the avoidance of doubt, as may be required under
applicable Laws in order to permit Parent to comply with all applicable requirements of the Securities Act and the Exchange Act in connection with the registration of all Registrable Securities of such Holder under the Securities Act). Upon any
disposal of Registrable Securities under the Registration Statement by a Holder, such Holder shall deliver to Parent a notice of transfer certifying such disposition and acknowledging compliance with the prospectus delivery requirements of the
Securities Act in connection therewith. 
 8. Delay of Registration. No Holder shall have any right to take any action to restrain,
enjoin, or otherwise delay any registration as the result of any controversy that might arise with respect to the interpretation or implementation of this Agreement. 

9. Sales Restrictions. 

(a) Notwithstanding any other provision of this Agreement, (i) the Holders may not sell Registrable Securities under the Registration
Statement so long as such Registrable Securities remain subject to an Employee Vesting Agreement or are Lock-up Securities that are subject to the Lock-up Period and
(ii) the Holders shall not be entitled to sell or otherwise transfer any Lock-up Securities that are subject to the Lock-up Period. 

(b) In addition to the restrictions set forth in Section 9(a), Garren Hilow (the “Key Holder”)
agrees that any sales by the Key Holder of Registrable Securities under the Registration Statement shall be limited (i) for the month of December 2021 (so long as sales are not made during the “blackout” period under Parent’s
insider trading policy), to a daily amount of no greater than 7% of the average daily trading volume of Parent’s common stock as reported on the Nasdaq Stock Market over the 10-day trading period prior to
the Closing (the “December Daily Limit”), and (ii) for all other periods (so long as sales are not made during a “blackout” period under Parent’s insider trading policy), to a daily amount of no greater than 5%
of the average daily trading volume of Parent’s common stock as reported on the Nasdaq Stock Market over the 10-day trading period prior to the Closing (the “Other Daily Limit” and
together with the December Daily Limit, the “Daily Limit”). The Key Holder, by acceptance of ownership of Parent Common Stock, agrees to comply in all respects with the provisions of this Section 9(b) and
consents to Parent making a notation in its records and giving instructions to any transfer agent of the Registrable Securities (the “Transfer Agent”), including stop transfer instructions, in order to implement the restrictions on
transfer set forth in this Section 9(b). Upon any sale of Registrable Securities under the Registration Statement by the Key Holder, the Key Holder shall deliver to Parent and the Transfer Agent a letter from the broker
effecting such sale, or other evidence of sale, indicating the number of Parent shares sold on behalf of the Key Holder, which number shall not exceed the applicable Daily Limit. Upon receipt of such letter or evidence and any other documentation
required by the Transfer Agent, Parent shall promptly instruct the Transfer Agent to remove the following legend from such shares, so long as such shares are not otherwise subject to any restriction on transfer: 

  
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 “THE SECURITIES REPRESENTED HEREBY MAY BE TRANSFERRED ONLY IN ACCORDANCE WITH THE TERMS OF AN AGREEMENT
BETWEEN THE COMPANY AND THE STOCKHOLDER, A COPY OF WHICH IS ON FILE WITH THE SECRETARY OF THE COMPANY.” 
 10. Rule 144 Holding
Period. The parties hereto agree that for purposes of Rule 144 promulgated by the SEC under the Securities Act, any Parent Common Stock issued to the Holders pursuant to the Merger Agreement or the Edgemont Side Letter, including the Subject
Securities, and the Parent Common Stock released from the Indemnity Holdback Fund, the Adjustment Holdback Fund and the Representative Holdback Amount shall be deemed to have been acquired by the Holders at the Effective Time, thus starting the
applicable Rule 144 holding period. 
 11. Notices. Any notice or other communication required or permitted to be delivered to any
party under this Agreement shall be made and given in compliance with the provisions of Section 10.1 of the Merger Agreement and, if to a Holder, to such Holder’s address set forth opposite each such Holder’s name on the Final
Spreadsheet. 
 12. Amendment of this Agreement. This Agreement may be amended, supplemented or otherwise modified only by a written
instrument executed by Parent, Edgemont and the Key Holder. 
 13. Governing Law. This Agreement, and all claims or causes of action
(whether in contract, tort or otherwise) that may be based upon, arise out of or relate to this Agreement or the negotiation, execution or performance of this Agreement (including any claim or cause of action based upon, arising out of or related to
any representation or warranty made in or in connection with this Agreement) shall be governed by and construed in accordance with the Laws of the State of Delaware, without giving effect to any Laws, rules or provisions that would cause the
application of the Laws of any jurisdiction other than the State of Delaware. 
 14. Exclusive Jurisdiction. Each of the parties
hereby irrevocably and unconditionally (i) submits, for itself and its property, to the exclusive jurisdiction of the Delaware Court of Chancery (or, only if the Delaware Court of Chancery declines to accept jurisdiction over a particular
matter, any Federal court of the United States of America sitting in the State of Delaware), and any appellate court from any thereof, in any Proceeding arising out of or relating to this Agreement or the negotiation, execution or performance
of this Agreement (including any claim or cause of action based upon, arising out of or related to any representation or warranty made in or in connection with this Agreement), or for recognition or enforcement of any judgment, and agrees that all
claims in respect of any such Proceeding shall be heard and determined in such Delaware Court of Chancery (or, only if the Delaware Court of Chancery declines to accept jurisdiction over a particular matter, any Federal court of the
United States of America sitting in the State of Delaware), (ii) waives, to the fullest extent it may legally and effectively do so, any objection which it may now or hereafter have to the laying of venue of any Proceeding arising out of
or relating to this Agreement or the negotiation, execution or performance of this Agreement (including any claim or cause of action based upon, arising out of or related to any representation or warranty made in or in connection with this
Agreement) in the Delaware Court of Chancery, any Federal court of the United States of America sitting in the State of Delaware, or in any Delaware State court, (iii) waives, to the fullest extent permitted by Law, the defense of an
inconvenient forum to the maintenance of such Proceeding in any such court and (iv) agrees that a final judgment in any such proceeding shall be conclusive and may be enforced in other jurisdictions by suit on the judgment or in any other
manner provided by Law. Each of the parties agrees that service of process, summons, notice or document by registered mail addressed to it in compliance with the provisions of Section 10.1 of the Merger Agreement and, if to a Holder, to such
Holder’s address set forth opposite each such Holder’s name on the Final Spreadsheet, shall, in each case, be effective service of process for any Proceeding brought in any such court. 

  
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 15. Waiver of Jury Trial. THE PARTIES HEREBY IRREVOCABLY AND UNCONDITIONALLY WAIVE
ANY RIGHT TO TRIAL BY JURY IN ANY ACTION, PROCEEDING OR COUNTERCLAIM ARISING OUT OF OR RELATING TO THIS AGREEMENT, THE TRANSACTION DOCUMENTS OR ANY TRANSACTION CONTEMPLATED HEREBY OR THEREBY OR THE ACTIONS OF THE PARTIES IN THE NEGOTIATION,
EXECUTION, PERFORMANCE AND ENFORCEMENT OF THIS AGREEMENT OR THE TRANSACTION DOCUMENTS, WHETHER NOW EXISTING OR HEREAFTER ARISING, AND WHETHER SOUNDING IN CONTRACT, TORT OR OTHERWISE. THE PARTIES AGREE THAT ANY OF THEM MAY FILE A COPY OF THIS
PARAGRAPH WITH ANY COURT AS WRITTEN EVIDENCE OF THE KNOWING, VOLUNTARY AND BARGAINED FOR AGREEMENT AMONG THE PARTIES IRREVOCABLY TO WAIVE TRIAL BY JURY AND THAT ANY PROCEEDING WHATSOEVER BETWEEN THEM RELATING TO THIS AGREEMENT, THE TRANSACTION
DOCUMENTS OR ANY TRANSACTION CONTEMPLATED HEREBY OR THEREBY SHALL INSTEAD BE TRIED IN A COURT OF COMPETENT JURISDICTION BY A JUDGE SITTING WITHOUT A JURY. 

16. Entire Agreement. This Agreement and the documents and instruments and other agreements specifically referred to herein, including
the Merger Agreement (and the documents, instruments and other agreements contemplated thereby), or delivered pursuant hereto constitute the entire agreement among the parties hereto with respect to the subject matter hereof and supersede all prior
agreements and understandings, both written and oral, among the parties hereto with respect to the subject matter hereof. 
 17.
Severability. If any provision of this Agreement shall be declared by any court of competent jurisdiction to be illegal, void or unenforceable, all other provisions of this Agreement and the application of such provision to
other Persons or circumstances other than those which it is determined to be illegal, void or unenforceable, shall not be impaired or otherwise affected and shall remain in full force and effect to the fullest extent permitted by applicable Law. The
parties further agree to replace such void or unenforceable provision of this Agreement with a valid and enforceable provision that will achieve, to the extent possible, the economic, business and other purposes of such void or unenforceable
provision. 
 18. Successors and Assigns. Subject to the provisions of Section 6, the provisions of this Agreement
shall inure to the benefit of, and shall be binding upon, the successors and permitted assigns of the parties hereto. 
 19. Third-Party
Beneficiaries. The holders of the Registrable Securities (and the Securityholders Representative on their behalf) are intended third-party beneficiaries of this Agreement and shall be bound by the terms of this Agreement and entitled to enforce
this Agreement against the undersigned in accordance with its terms. 
 20. Specific Performance and Other Remedies.  

(a) The parties to this Agreement agree that, in the event of any breach or threatened breach by the other party or parties hereto, or any
Holder of any covenant, obligation or other agreement set forth in this Agreement or any Transaction Document, as the case may be, (i) each party hereto shall be entitled, without any proof of actual damages (and in addition to any other remedy
that may be available to it), to an order of specific performance or mandamus to enforce the observance and performance of such covenant, obligation or other agreement and an injunction preventing or restraining such breach or threatened breach, and
(ii) no party hereto shall be required to provide or post any bond or other security or collateral in connection with any such order or injunction or in connection with any related action or legal proceeding. 

  
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 (b) Any and all remedies herein expressly conferred herein upon a party hereto shall be
deemed to be cumulative with, and not exclusive of, any other remedy conferred hereby, or by law or in equity upon such party, and the exercise by a party hereto of any one remedy will not preclude the exercise of any other remedy. 

21. Construction. Section 1.2(b) of the Merger Agreement is incorporated by reference herein, mutatis mutandis. Any
rule of construction to the effect that ambiguities are to be resolved against the drafting party shall not be applied in the construction or interpretation of this Agreement. Neither the drafting history nor the negotiating history of this
Agreement shall be used or referred to in connection with the construction or interpretation of this Agreement. 
 22. Counterparts.
This Agreement may be executed in two or more counterparts, each of which shall be deemed to be an original and all of which together shall be deemed to be one and the same instrument. Copies of executed counterparts transmitted by electronic
signature (including by means of email in .pdf format) shall be considered original executed counterparts for purposes of this Section. 

23. Termination. This Agreement shall terminate and cease to be of any force and effect upon the earliest of (i) termination of
the Merger Agreement and (ii) the Registration Termination Date. For clarity, the obligations under Section 4, Section 5 and Sections 11 through this
Section 23 will survive any termination of this Agreement. 
 [Signature Page Follows] 

  
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 IN WITNESS WHEREOF, the parties hereto have executed this Agreement on the date first above
written. 
  

			
	PARENT:
	
	Twist Bioscience Corporation
		
	By:	 	/s/ Emily Leproust
	Name:	 	Emily Leproust
	Title:	 	Chief Executive Officer


  

  
 Signature Page to
Registration Rights Agreement 












 
			
		
	HOLDER:	 	/s/ Aaron Winters
		 	Aaron Winters
		
	HOLDER:	 	/s/ Alan Hatch
		 	Alan Hatch
		
	HOLDER:	 	/s/ Burt Adelman
		 	Burt Adelman
		
	HOLDER:	 	CAZ Investments, LLC
		
		 	/s/ Shannon Zollo
		 	Shannon Zollo
		 	Managing Member
		
	HOLDER:	 	/s/ Devin Turner
		 	Devin Turner
		
	HOLDER:	 	/s/ Garren Hilow
		 	Garren Hilow
		
	HOLDER:	 	Generation Investments, LLC
		
		 	/s/ Burt Adelman
		 	Burt Adelman, Manager
		
	HOLDER:	 	/s/ Graham Farrington
		 	Graham Farrington
		
	HOLDER:	 	Kasser Family Management
		
		 	/s/ Owen Kasser
		 	Owen Kasser, Member
		
	HOLDER:	 	Garren R. Hilow 2021 Irrevocable Trust
		
		 	/s/ Katharine M. Hilow
		 	Katharine M. Hilow, Trustee


  

  
 Signature Page to
Registration Rights Agreement 












 
			
	 HOLDER:
	 	 /s/ Michael McKenna

		 	 Michael McKenna

		
	 HOLDER:
	 	 /s/ Michael Montalbano

		 	 Michael Montalbano

		
	 HOLDER:
	 	 /s/ Steve Wishner

		 	 Steve Wishner

		
	 HOLDER:
	 	 /s/ Steven Tardanico

		 	 Steven Tardanico




  
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	 EDGEMONT:

	
	 Edgemont Capital Partners, L.P.

		
	 By:
	 	 /s/ David Blume

	 Name: David Blume

	 Title: Managing Director




  
 Signature Page to
Registration Rights Agreement 












 EXHIBIT A 

JOINDER AGREEMENT 

Reference is made to (i) the Registration Rights Agreement (as amended from time to time or any successor agreement thereto, the
“Registration Rights Agreement”), dated as of December 1, 2021, by and among Twist Bioscience Corporation, a Delaware corporation (“Parent”), Edgemont Capital Partners, L.P. and each Holder set forth on the
signature pages thereto (or who delivers an executed joinder agreement thereto), and (ii) the Agreement and Plan of Merger and Reorganization (the “Merger Agreement”), dated as of November 19, 2021, by and among Parent,
Nautilus Acquisition Sub, Inc., a Delaware corporation, AbX Biologics, Inc. (d/b/a Abveris) a Delaware corporation (the “Company”), and the Securityholder Representative. 

Pursuant to and in accordance with Section 2(a) of the Registration Rights Agreement, the undersigned hereby acknowledges and agrees
that, effective as of the Closing (as defined in the Merger Agreement), the undersigned is a Holder (as defined in the Registration Rights Agreement) and shall be bound by all the terms and conditions of the Registration Rights Agreement as though
an original party thereto. 
 IN WITNESS WHEREOF, the undersigned has executed this joinder agreement as of ___________, 2021. 

 

	
	 ADDITIONAL PARTNER

	
	   

	 Signature

	
	 Name:

	 Title:

	
	 Address:

	
	
                  
                              

	
                  
                              

	
	 Email: _________________




  
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