EX-10.4





 Exhibit 10.4 

UNIT PURCHASE AGREEMENT 

This UNIT PURCHASE AGREEMENT (this “Agreement”) is made as of the 2 day of December 2021, by and between BioPlus Acquisition
Corp., a Cayman Islands exempted company (the “Company”), having its principal place of business at 260 Madison Avenue, Suite 800, New York, NY 10016, and BioPlus Sponsor LLC, a Cayman Islands limited liability company, having
its principal place of business at 533 Airport Blvd, Suite 400, Burlingame, CA 94010 (the “Subscriber”). 
 WHEREAS, the
Company desires to sell on a private placement basis (the “Offering”) an aggregate of 380,000 units (“Units”) of the Company, each Unit comprised of one Class A ordinary share of the Company, par value $0.0001
per share (“Ordinary Shares”), and one half of one warrant to purchase one Class A ordinary share (“Warrant”), for a purchase price of $3,800,000, or $10.00 per Unit. The Ordinary Shares underlying the Warrants
are hereinafter referred to as the “Warrant Shares.” The Ordinary Shares underlying the Units (excluding the Warrant Shares) are hereinafter referred to as the “Placement Shares.” The Warrants underlying the
Units are hereinafter referred to as the “Placement Warrants.” The Units, Placement Shares, Placement Warrants and Warrant Shares, collectively, are hereinafter referred to as the “Securities.” Placement
Warrants may be exercised only to the extent that, when aggregated with other Placement Warrants being exercised, the exercise is for a whole share or whole shares; no fractional shares shall be issuable. The exercise price for any Warrant Share
shall be $11.50. Subject to the foregoing, the Placement Warrants are exercisable during the period commencing 30 days following the completion of the Company’s initial business combination (the “Business Combination”), as such
term is defined in the registration statement filed in connection with the IPO, as amended at the time it becomes effective (the “Registration Statement”), and expiring on the fifth anniversary of the completion of the Business
Combination; and 
 WHEREAS, the Subscriber wishes to purchase the Units from the Company and the Company wishes to accept such subscription
from the Subscriber. 
 NOW, THEREFORE, in consideration of the premises and the mutual covenants hereinafter set forth and other good and
valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Company and the Subscriber hereby agree as follows: 
  

	 	1.	 Agreement to Subscribe 



1.1 Purchase and Issuance of the Units. Upon the terms and subject to the conditions of this Agreement, the Subscriber hereby
agrees to purchase from the Company, and the Company hereby agrees to sell to the Subscriber, simultaneously with the closing of the IPO on or before December 7, 2021 (the “Initial Closing Date”), 380,000 Units for a purchase
price of $3,800,000 (the “Purchase Price”). 
 1.2 Delivery of the Purchase Price. Upon execution of this
Agreement, the Company is bound to fulfill its obligations hereunder and the Subscriber hereby irrevocably commits to deliver directly into a trust account (the “Trust Account” ) held at JP Morgan Chase Bank, N.A.
or any other financial institution chosen by the Company, with Continental Stock Transfer & Trust Company acting as trustee (“Continental”), the Purchase Price in immediately available funds by wire transfer or such other
form of payment as shall be acceptable to Continental, in its sole and absolute discretion, one (1) business day prior to the effective date of the Registration Statement. 

1.3 Termination. This Agreement and each of the obligations of the undersigned shall be null and void and without effect if the
Closing does not occur prior to June 30, 2022. 
  

	 	2.	 Representations and Warranties of Subscriber 



The Subscriber represents and warrants to the Company that: 

2.1 No Government Recommendation or Approval. Subscriber understands that no federal or state agency has passed upon or made any
recommendation or endorsement of the Company or the Offering of the Securities. 












 2.2 Accredited Investor. Subscriber represents that it is an “accredited
investor” as such term is defined in Rule 501(a) of Regulation D under the Securities Act of 1933, as amended (the “Securities Act”), and acknowledges that the sale contemplated hereby is being made in reliance, among other
things, on a private placement exemption to “accredited investors” under the Securities Act and similar exemptions under state law. 

2.3 Intent. Subscriber is purchasing the Securities solely for investment purposes, for such Subscriber’s own account (and/or
for the account or benefit of its members or affiliates, as permitted, pursuant to the terms of an agreement (the “Letter Agreement”) to be entered into with respect to the Securities between, among others, Subscriber and the
Company, as described in the Registration Statement), and not with a view to the distribution thereof and Subscriber has no present arrangement to sell the Securities to or through any person or entity except as may be permitted under the Letter
Agreement. Subscriber shall not engage in hedging transactions with regard to the Securities unless in compliance with the Securities Act. 

2.4 Restrictions on Transfer. Subscriber acknowledges and understands the Units are being offered in a transaction not involving a
public offering in the United States within the meaning of the Securities Act. The Securities have not been registered under the Securities Act and, if in the future Subscriber decides to offer, resell, pledge or otherwise transfer the
Securities, such Securities may be offered, resold, pledged or otherwise transferred only (A) pursuant to an effective registration statement filed under the Securities Act, (B) pursuant to an exemption from registration under Rule 144
promulgated under the Securities Act, if available, or (C) pursuant to any other available exemption from the registration requirements of the Securities Act, and in each case in accordance with any applicable securities laws of any state or
any other jurisdiction. Notwithstanding the foregoing, Subscriber acknowledges and understands the Securities are subject to transfer restrictions as described in Section 8 hereof. Subscriber agrees that, if any transfer of its Securities
or any interest therein is proposed to be made, as a condition precedent to any such transfer Subscriber may be required to deliver to the Company an opinion of counsel satisfactory to the Company with respect to such transfer. Absent registration
or another available exemption from registration, Subscriber agrees it will not transfer the Securities (unless otherwise permitted pursuant to the Letter Agreement, as described in the Registration Statement). Subscriber further acknowledges
that because the Company is a shell company, Rule 144 may not be available to Subscriber for the resale of the Securities until the one year anniversary following completion of the Business Combination, despite technical compliance with the
requirements of Rule 144 and the release or waiver of any contractual transfer restrictions. 
 2.5 Sophisticated Investor. 

(i) Subscriber’s managers and members are individually accredited investors and are sophisticated in financial matters and able to
evaluate the risks and benefits of the investment in the Securities. 
 (ii) Subscriber is aware that an investment in the Securities is
highly speculative and subject to substantial risks because, among other things, (a) the Securities are subject to transfer restrictions and have not been registered under the Securities Act and therefore cannot be sold unless subsequently
registered under the Securities Act or an exemption from such registration is available and (b) Subscriber has waived its redemption rights with respect to the Securities as set forth in Section 5 hereof, and the Securities held by
Subscriber are not entitled to, and have no right, interest or claim to any monies held in the Trust Account, and accordingly Subscriber may suffer a loss of a portion or all of its investment in the Securities. Subscriber is able to bear the
economic risk of its investment in the Securities for an indefinite period of time.
 2.6 Independent Investigation. Subscriber,
in making the decision to purchase the Units, has relied upon an independent investigation of the Company and has not relied upon any information or representations made by any third parties or upon any oral or written representations or assurances
from the Company, its officers, directors or employees or any other representatives or agents of the Company, other than as set forth in this Agreement. Subscriber is familiar with the business, operations and financial condition of the Company and
has had an opportunity to ask questions of, and receive answers from the Company’s officers and directors concerning the Company and the terms and conditions of the Offering and has had full access to such other information concerning the
Company as Subscriber has requested. Subscriber confirms that all documents that it has requested have been made available and that Subscriber has been supplied with all of the additional information concerning this investment which Subscriber has
requested. 

  
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 2.7 Organization and Authority. Subscriber is duly organized, validly existing
and in good standing under the laws of the Cayman Islands and it possesses all requisite power and authority necessary to carry out the transactions contemplated by this Agreement. 

2.8 Authority. This Agreement has been validly authorized, executed and delivered by Subscriber and is a valid and binding
agreement enforceable in accordance with its terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent conveyance, moratorium, reorganization, or similar laws relating to, or affecting generally the
enforcement of, creditors’ rights and remedies or by equitable principles of general application and except as enforcement of rights to indemnity and contribution may be limited by federal and state securities laws or principles of public
policy. 
 2.9 No Conflicts. The execution, delivery and performance of this Agreement and the completion by Subscriber of the
transactions contemplated hereby do not violate, conflict with or constitute a default under (i) Subscriber’s charter documents, (ii) any agreement or instrument to which Subscriber is a party or (iii) any law, statute, rule or
regulation to which Subscriber is subject, or any agreement, order, judgment or decree to which Subscriber is subject. 
 2.10 No Legal
Advice from Company. Subscriber acknowledges it has had the opportunity to review this Agreement and the transactions contemplated by this Agreement and the other agreements entered into between the parties hereto with
Subscriber’s own legal counsel and investment and tax advisors. Except for any statements or representations of the Company made in this Agreement and the other agreements entered into between the parties hereto, Subscriber is relying
solely on such review, counsel and advisors and not on any statements or representations of the Company or any of its representatives or agents for legal, tax or investment advice with respect to this investment, the transactions contemplated by
this Agreement or the securities laws of any jurisdiction. 
 2.11 Reliance on Representations and Warranties. Subscriber
understands the Units are being offered and sold to Subscriber in reliance on exemptions from the registration requirements under the Securities Act, and analogous provisions in the laws and regulations of various states, and that the Company is
relying upon the truth and accuracy of the representations, warranties, agreements, acknowledgments and understandings of Subscriber set forth in this Agreement in order to determine the applicability of such provisions. 

2.12 No General Solicitation. Subscriber is not subscribing for the Units as a result of or subsequent to any general solicitation
or general advertising, including but not limited to any advertisement, article, notice or other communication published in any newspaper, magazine, or similar media or broadcast over television or radio, or presented at any seminar or meeting or in
a registration statement with respect to the IPO filed with the Securities and Exchange Commission (“SEC”). 
 2.13
Legend. Subscriber acknowledges and agrees the certificates evidencing each of the Securities shall bear a restrictive legend (the “Legend”), in form and substance substantially as set forth in Section 4 hereof. 

 

	 	3.	 Representations, Warranties and Covenants of the Company 



The Company represents and warrants to, and agrees with, Subscriber that: 

3.1 Valid Issuance of Shares. The total number of shares of all classes of ordinary and preferred shares which the Company
has authority to issue is 500,000,000 Class A ordinary shares, 50,000,000 Class B ordinary shares and 5,000,000 preference shares (“Preferred Shares”). As of the date hereof, the Company has issued and outstanding
5,175,000 Class B ordinary shares (of which up to 675,000 shares are subject to forfeiture) and no Preferred Shares. All of the issued ordinary shares of the Company have been duly authorized, validly issued, and are fully paid and non-assessable. 
 3.2 Title to Securities. Upon issuance in accordance with, and payment
pursuant to, the terms hereof and the Warrant Agreement (as defined in Section 8.1), as the case may be, each of the Units, Placement Shares, Placement Warrants and the Warrant Shares will be duly and validly issued, fully paid and non-assessable. On the 

  
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date of issuance of the Units, the Warrant Shares shall have been reserved for issuance. Upon issuance in accordance with, and payment pursuant to, the terms hereof and the Warrant Agreement, as
the case may be, the Subscriber will have or receive good title to the Units, Placement Shares and Placement Warrants, free and clear of all liens, claims and encumbrances of any kind resulting from actions of, or any failure to act by, the Company,
other than (i) transfer restrictions hereunder and pursuant to the Letter Agreement and (ii) transfer restrictions under federal and state securities laws. 

3.3 Organization and Qualification. The Company is an exempted company, validly existing and in good standing under the
laws of the Cayman Islands and has the requisite corporate power to own its properties and assets and to carry on its business as now being conducted. 

3.4 Authorization; Enforcement. (i) The Company has the requisite corporate power and authority to enter into and perform its
obligations under this Agreement and to issue the Securities in accordance with the terms hereof, (ii) the execution, delivery and performance of this Agreement by the Company and the completion by it of the transactions contemplated hereby
have been duly authorized by all necessary corporate action, and no further consent or authorization of the Company or its Board of Directors or shareholders is required, and (iii) this Agreement constitutes a valid and binding obligation of
the Company enforceable against the Company in accordance with its terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent conveyance, moratorium, reorganization, or similar laws relating to, or affecting
generally the enforcement of, creditors’ rights and remedies or by equitable principles of general application and except as enforcement of rights to indemnity and contribution may be limited by federal and state securities laws or principles
of public policy. 
 3.5 No Conflicts. The execution, delivery and performance of this Agreement and the completion by the
Company of the transactions contemplated hereby do not (i) result in a violation of the Company’s amended and restated memorandum and articles of association, (ii) conflict with, or constitute a default under any agreement or
instrument to which the Company is a party or by which it is bound or (iii) violate any law statute, rule or regulation to which the Company is subject or any agreement, order, judgment or decree to which the Company is subject. Other than any
SEC or state securities filings which may be required to be made by the Company subsequent to the Closing, and any registration statement which may be filed pursuant thereto, the Company is not required under federal, state or local law, rule or
regulation to obtain any consent, authorization or order of, or make any filing or registration with, any court or governmental agency or self-regulatory entity in order for it to perform any of its obligations under this Agreement or issue the
Units, Placement Shares, Placement Warrants or the Warrant Shares in accordance with the terms hereof. 
  

	 	4.	 Legends 



4.1 Legend. The Company will issue the Units, Placement Shares and Placement Warrants, and, when issued, the Warrant Shares, purchased
by Subscriber in the name of Subscriber. The Securities will bear the following Legend and appropriate “stop transfer” instructions: 

“THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES
ACT”), OR ANY STATE SECURITIES LAWS AND NEITHER THESE SECURITIES NOR ANY INTEREST THEREIN MAY BE OFFERED, SOLD, TRANSFERRED, PLEDGED OR OTHERWISE DISPOSED OF EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR
SUCH LAWS OR AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT AND SUCH LAWS WHICH, IN THE OPINION OF COUNSEL FOR THIS CORPORATION, IS AVAILABLE.” 

“THE SECURITIES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO RESTRICTIONS ON TRANSFER PURSUANT TO A LETTER AGREEMENT AMONG BIOPLUS
ACQUISITION CORP. AND THE OTHER PARTIES THERETO AND MAY ONLY BE OFFERED, SOLD, TRANSFERRED, PLEDGED OR OTHERWISE DISPOSED OF DURING THE TERM THEREOF PURSUANT TO THE TERMS SET FORTH IN THE LETTER AGREEMENT.” 

  
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 4.2 Subscriber’s Compliance. Nothing in this Section 4 shall
affect in any way Subscriber’s obligations and agreements to comply with all applicable securities laws upon resale of the Securities. 

4.3 Company’s Refusal to Register Transfer of the Securities. The Company shall refuse to register any transfer of the
Securities if, in the sole judgment of the Company, such purported transfer would not be made (i) pursuant to an effective registration statement filed under the Securities Act, or (ii) pursuant to an available exemption from the
registration requirements of the Securities Act and applicable state securities laws and (iii) in compliance herewith and with the Letter Agreement. 

4.4 Registration Rights. The Subscriber will be entitled to certain registration rights which will be governed by a registration
rights agreement (“Registration Rights Agreement”) to be entered into between, among others, Subscriber and the Company, on or prior to the effective date of the Registration Statement.

 

	 	5.	 Waiver of Liquidation Distributions. 



In connection with the Securities purchased pursuant to this Agreement, the Subscriber hereby waives any and all right, title, interest or
claim of any kind in or to any distributions with respect to the Securities in connection with (i) the exercise of redemption rights in connection with the Company’s completion of the Business Combination, or (ii) upon the
Company’s redemption of Ordinary Shares upon the Company’s failure to complete the Business Combination within 18 months from the completion of the IPO or the liquidation of the Company prior to the expiration of such 18 month
period. In the event any Subscriber purchases Ordinary Shares in the IPO or in the aftermarket (“Public Shares”), Subscriber hereby waives any and all right, title, interest or claim of any kind in or to any distributions with
respect to any Public Shares in connection with the exercise of redemption rights in connection with the Company’s completion of the Business Combination. For the avoidance of doubt, Subscriber shall be eligible to redeem any Public Shares upon
the same terms offered to all other purchasers of Ordinary Shares in the IPO in the event the Company fails to complete the Business Combination, or liquidates, within 18 months from the completion of the IPO. 

 

	 	6.	 Termination of Placement Warrants. 



6.1 Failure to Complete Business Combination. The Placement Warrants shall be terminated upon the dissolution of the Company
or in the event that the Company does not complete the Business Combination within 18 months from the completion of the IPO. 
 6.2
Termination of Rights as Holder. If the Placement Warrants are terminated in accordance with Section 6.1, then after such time, Subscriber (or its successor in interest) shall no longer have any rights as a holder of such Placement
Warrants and the Company shall take such action as is appropriate to cancel such Placement Warrants. The Subscriber hereby irrevocably grants the Company a limited power of attorney for the purpose of effectuating the foregoing and agrees to take
any and all measures reasonably requested by the Company necessary to effect the foregoing. 
  

	 	7.	 Rescission Right Waiver and Indemnification. 



7.1 The Subscriber understands and acknowledges an exemption from the registration requirements of the Securities Act requires
there be no general solicitation of purchasers of the Units. In this regard, if the IPO were deemed to be a general solicitation with respect to the Units, the offer and sale of such Units may not be exempt from registration and, if not, the
Subscriber may have a right to rescind its purchases of the Units. In order to facilitate the completion of the Offering and in order to protect the Company, its shareholders and the amounts in the Trust Account from claims that may adversely affect
the Company or the interests of its shareholders, Subscriber hereby agrees to waive, to the maximum extent permitted by applicable law, any claims, right to sue or rights in law or arbitration, as the case may be, to seek rescission of its purchase
of the Units. The Subscriber acknowledges and agrees this waiver is being made in order to induce the Company to sell the Units to Subscriber. The Subscriber agrees the foregoing waiver of rescission rights shall apply to any and all known or
unknown actions, causes of action, suits, claims or proceedings (collectively, “Claims”) and related losses, costs, penalties, fees, liabilities and damages, whether compensatory, consequential or exemplary, and expenses in
connection therewith, including reasonable attorneys’ and expert witness fees and disbursements and all other expenses reasonably incurred in investigating, preparing or defending against any Claims, whether pending or threatened, in connection
with any present or future actual or asserted right to rescind the purchase of the Units hereunder or relating to the purchase of the Units and the transactions contemplated hereby. 

  
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 7.2 The Subscriber agrees not to seek recourse against the Trust Account
for any reason whatsoever in connection with its purchase of the Units or any Claim that may arise now or in the future. 

7.3 The Subscriber acknowledges and agrees that the shareholders of the Company are and shall be third-party beneficiaries
of this Section 7.
 7.4 The Subscriber agrees that, to the extent any waiver of rights under this Section 7 is
ineffective as a matter of law, Subscriber has offered such waiver for the benefit of the Company as an equitable right that shall survive any statutory disqualification or bar that applies to a legal right. The Subscriber acknowledges the receipt
and sufficiency of consideration received from the Company hereunder in this regard. 
  

	 	8.	 Terms of the Units and Placement Warrant 



The Units and their component parts are substantially identical to the units to be offered in the IPO except that: (i) the Units and their
component parts will be subject to transfer restrictions, except in limited circumstances, until 30 days following the completion of the Business Combination, (ii) the Units and their component parts are being purchased pursuant to an exemption
from the registration requirements of the Securities Act and will become freely tradable only after they are registered or an exemption from registration is available, and the restrictions described above in clause (i) have expired. 

 

	 	9.	 Governing Law; Jurisdiction; Waiver of Jury Trial 



This Agreement shall be governed by and construed in accordance with the laws of the State of New York for agreements made and to be wholly
performed within such state. The parties hereto hereby waive any right to a jury trial in connection with any litigation pursuant to this Agreement and the transactions contemplated hereby. 

 

	 	10.	 Assignment; Entire Agreement; Amendment 



10.1 Assignment. Neither this Agreement nor any rights hereunder may be assigned by any party to any other person other than by a
Subscriber to a person agreeing to be bound by the terms hereof, including the waiver contained in Section 7 hereof. 
 10.2 Entire
Agreement. This Agreement sets forth the entire agreement and understanding between the parties as to the subject matter hereof and merges and supersedes all prior discussions, agreements and understandings of any and every nature among
them. 
 10.3 Amendment. Except as expressly provided in this Agreement, neither this Agreement nor any term hereof may be
amended, waived, discharged or terminated other than by a written instrument signed by the party against whom enforcement of any such amendment, waiver, discharge or termination is sought. 

10.4 Binding upon Successors. This Agreement shall be binding upon and inure to the benefit of the parties hereto and to
their respective heirs, legal representatives, successors and permitted assigns.
  

	 	11.	 Notices 



11.1 Notices. Unless otherwise provided herein, any notice or other communication to a party hereunder shall be sufficiently given if in
writing and personally delivered or sent by facsimile or other electronic transmission with copy sent in another manner herein provided or sent by courier (which for all purposes of this Agreement shall include Federal Express or other recognized
overnight courier) or mailed to said party by certified mail, return receipt requested, at its address provided for herein or such other address as either may designate for itself in such notice to the other. Communications shall be deemed to
have been received when delivered personally, on the scheduled arrival date when sent by next day or 2nd-day courier service, or if sent by facsimile upon receipt of


  
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confirmation of transmittal or, if sent by mail, then three days after deposit in the mail. If given by electronic transmission, such notice shall be deemed to be delivered (a) if by
electronic mail, when directed to an electronic mail address at which the recipient has consented to receive notice; (b) if by a posting on an electronic network together with separate notice to the recipient of such specific posting, upon the
later of (1) such posting and (2) the giving of such separate notice; and (c) if by any other form of electronic transmission, when directed to the recipient. 
  

	 	12.	 Counterparts 



This Agreement may be executed in two or more counterparts, all of which when taken together shall be considered one and the same agreement and
shall become effective when counterparts have been signed by each party and delivered to the other party, it being understood that both parties need not sign the same counterpart. In the event that any signature is delivered by facsimile
transmission or by e-mail delivery of a “pdf” format data file, such signature shall create a valid and binding obligation of the party executing (or on whose behalf such signature is executed) with
the same force and effect as if such facsimile or “.pdf” signature page were an original thereof. 
  

	 	13.	 Survival; Severability 



13.1 Survival. The representations, warranties, covenants and agreements of the parties hereto shall survive the Closing. 

13.2 Severability. In the event that any provision of this Agreement becomes or is declared by a court of competent jurisdiction to be
illegal, unenforceable or void, this Agreement shall continue in full force and effect without said provision; provided that no such severability shall be effective if it materially changes the economic benefit of this Agreement to any party. 

 

	 	14.	 Headings. 



The titles and subtitles used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this
Agreement. 
 [remainder of page intentionally left blank] 

  
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 Accepted and agreed on the date set forth above. 

 

			
	BIOPLUS ACQUISITION CORP.
		
	By:	 	 /s/ Ross Haghighat

		 	Name: Ross Haghighat
		 	Title: Chief Executive Officer and Chief Financial Officer


 Accepted and agreed on the date set forth above. 

 

			
	SUBSCRIBER:
	
	BIOPLUS SPONSOR LLC
		
	By:	 	 /s/ Steven Fletcher

		 	Name: Steven Fletcher
		 	Title: Managing Member
		
	By:	 	 /s/ Alex Vieux

		 	Name: Alex Vieux
		 	Title: Managing Member


 [BioPlus Acquisition Corp. Placement Unit Purchase Agreement] 

  
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