----

Registration No. 333-153447

----

----

| Colorado(State      or Other Jurisdiction ofIncorporation      or Organization) | 84-1250533(I.R.S.      Employer Identification No.) |
|---------------------------------------------------------------------------------|-----------------------------------------------------|

CALCULATION OF REGISTRATION FEE

| Title      of Each Class of SecuritiesTo      be Registered | Amountto      beRegistered(1)(2) | Proposed      MaximumOffering      PricePer      Share(3) | Proposed      MaximumAggregate      Offering Price(3) | Amount      of Registration Fee(4) |
|-------------------------------------------------------------|----------------------------------|-----------------------------------------------------------|-------------------------------------------------------|------------------------------------|
| Common      Stock, par value $0.01 per share                | 3,313,670                        | $9.395                                                    | $36,568,730                                           | $1,437.20                          |

| (1) | Pursuant      to Instruction E of Form S-8 and the telephone interpretation of the      Securities and Exchange Commission set forth in Section G. Securities Act      Forms, No. 89, of the Division of Corporation Finance’s Manual of Publicly      Available Telephone Interpretations dated July 1997, the 3,313,670 shares      being registered includes 1,313,670 shares (the “Carryover Shares”) that      were previously available for issuance under the Cenveo, Inc. 2001      Long-Term Equity Incentive Plan, as amended to date (the “2001 Plan”) but      that have been carried forward to, and included in the reserve available      for issuance under, the Cenveo, Inc. 2007 Long-Term Equity Incentive Plan,      as amended to date (the “2007 Plan”).  The Carryover Shares were      previously registered on the Form S-8 (Registration No. 333-118861), which      was filed on September 7, 2004 (the “Prior Registration      Statement”).  Pursuant to a contemporaneously filed      post-effective amendment to the Prior Registration Statement, the      Carryover Shares are being deregistered from the Prior Registration      Statement and transferred to this Registration Statement, together with      the associated registration fees, for delivery under the 2007      Plan.  To the extent any additional shares that remain subject      to outstanding awards under the 2001 Plan otherwise would have been      returned to the 2001 Plan on account of the expiration, cancellation or      forfeiture thereof, those shares will instead be included in the shares      reserved for issuance under the 2007 Plan.  Accordingly,      Post-effective amendments to this Registration Statement may periodically      be filed in order to carry-over such shares from the 2001 Plan to the 2007      Plan. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

----

| (2) | This      Registration Statement also relates to such indeterminate number of      additional shares as may be issuable pursuant to stock splits, stock      dividends, or similar transactions. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (3) | The      proposed maximum offering price per share of Common Stock and the proposed      maximum aggregate offering price are calculated solely for the purpose of      determining the registration fee pursuant to Rule 457(h) under the      Securities Act of 1933.  With respect to 640,000 shares of      Common Stock as to which stock options were granted prior to the date      hereof, the registration fee is based on the option exercise price of      $17.89 per share, and with respect to the balance of the shares being      registered (consisting of 2,673,670 shares of Common Stock), the fee is      based on a price of $9.395 per share, which is the average of the high      ($9.71) and low ($9.08) sales prices of the Common Stock on September 5,      2008 on the New York StockExchange. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (4) | Pursuant      to Rule 457(p) under the Securities Act of 1933, the $1,437.20 aggregate      total registration fee for the 3,313,670 shares registered on this      Registration Statement is offset by registration fees in the amount of      $313.27 previously paid with respect to the Carryover Shares in connection      with the Prior Registration Statement.  Accordingly, the      Registrant is currently paying a registration fee of $1,123.93 in      connection with the filing of this Registration  Statement. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

----

----

----

|   | • | the      Company’s Annual Report on Form 10-K for the year ended December 31,      2007; |
|--------|---------|------------------------------------------------------------------------------------------------|

|   | • | the      Company’s Quarterly Reports on Form 10-Q for the quarters ended March 29,      2008 and June 28, 2008; |
|--------|---------|-----------------------------------------------------------------------------------------------------------------------|

|   | • | the      Company’s Current Reports on Form 8-K filed January 24, 2008, February 1,      2008, February 27, 2008, February 29, 2008, March 14, 2008, April 1, 2008,      May 8, 2008, June 5, 2008, June 13, 2008, July 8, 2008 and August 7, 2008,      as well as the amendments to the Company’s Current Reports on Form 8-K      filed June 18, 2008 and July 1,2008. |
|--------|---------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | the      description of the Company’s Common Stock contained in the Company’s      registration statements therefor and subsequent amendments      thereof. |
|--------|---------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

----

----

| Exhibit      No. | Description                                                                                                                                                                                                                                                                                                                                                         |
|------------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 4.1              | Articles      of Incorporation of Cenveo, Inc. (incorporated by reference to Exhibit 3.1      to the Company’s Quarterly Report on Form 10-Q for the quarter ended June      30, 1997, as filed with the SEC on August 14, 1997)                                                                                                                         |
| 4.2              | Amendment      to Articles of Incorporation of Cenveo, Inc. (incorporated by reference to      Exhibit 3.2 to the Company’s Quarterly Report on Form 10-Q for the quarter      ended June 30, 2004, as filed with the SEC on August 2, 2004)                                                                                                             |
| 4.3              | Amendment      to Articles of Incorporation and Certificate of Designations of Series A      Junior Participating Preferred Stock of Cenveo, Inc. (incorporated by      reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K dated      (date of earliest event reported) April 17, 2005, as filed with the SEC on      April 21, 2005)  |
| 4.4              | Amended      and Restated Bylaws of Cenveo, Inc.  (incorporated by reference      to Exhibit 3.2 to the Company’s Current Report on Form 8-K dated (date of      earliest event reported) February 22, 2007, as filed with the SEC on      August 30, 2007)                                                                                    |
| 4.5              | Cenveo,      Inc. 2007 Long-Term Equity Incentive Plan (incorporated by reference to      Exhibit 10.1 to the Company’s Quarterly Report on Form 10-Q for the      quarter ended June 30, 2007, as filed with the SEC on August 8,      2007)                                                                                                            |
| 4.6              | Amendment      to the Cenveo, Inc. 2007 Long-Term Equity Incentive Plan (incorporated by      reference as Exhibit A to the Company’s Definitive 14A, as filed with the      SEC on April 28, 2008)                                                                                                                                                      |
| 5.1              | Opinion      of Timothy M. Davis, the Company’s General Counsel                                                                                                                                                                                                                                                                                          |
| 23.1             | Consent      of Deloitte & Touche LLP                                                                                                                                                                                                                                                                                                                      |
| 23.2             | Consent      of Ernst & Young LLP                                                                                                                                                                                                                                                                                                                          |
| 23.3             | Consent      of Timothy M. Davis (included in Exhibit 5.1)                                                                                                                                                                                                                                                                                                     |
| 24.1             | Powers      of Attorney (included in signature page to this Registration      Statement)                                                                                                                                                                                                                                                                       |

| A. | The undersigned      registrant hereby undertakes: |
|----|----------------------------------------------------|

|   | (1)     | To file, during any      period in which offers or sales are being made, a post-effective amendment      to the registration statement: |
|--------|-----------------------------|-----------------------------------------------------------------------------------------------------------------------------------------|

|   |   | (i) | To include any      prospectus required by section 10(a)(3) of the Securities  Act; |
|--------|--------|-----|-------------------------------------------------------------------------------------|

|   |   | (ii) | To reflect in the      prospectus any facts or events arising after the effective date of the      registration statement (or the most recent post-effective amendment      thereof) which, individually or in the aggregate, represent    a |
|--------|--------|------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

----

|   |   |   | fundamental change      in the information set forth in the registration statement.       Notwithstanding the foregoing, any increase or decrease in volume of      securities offered (if the total dollar value of securities offered would      not exceed that which was registered) and any deviation from the low or      high end of the estimated maximum offering range may be reflected in the      form of prospectus filed with the SEC pursuant to Rule 424(b) if, in the      aggregate, the changes in volume and price represent no more than 20%      change in the maximum aggregate offering price set forth in the      “Calculation of Registration Fee” table in the effective registration      statement. |
|--------|--------|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   |   | (iii) | To include any      material information with respect to the plan of distribution not      disclosed previously in the registration statement or any material change      to such information in the registration  statement; |
|--------|--------|-------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   |   |   | Provided however,      that paragraphs (a)(1)(i) and (a)(1)(ii) of this section      do not apply if the registration statement is on Form S-8, and the      information required to be included in a post-effective amendment by those      paragraphs is contained in reports filed with or furnished to the SEC by      the registrant pursuant to section 13 or section 15(d) of the Exchange Act      that are incorporated by reference in the registration      statement. |
|--------|--------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | (2)     | That, for the      purpose of determining any liability under the Securities Act, each such      post-effective amendment shall be deemed to be a new registration      statement relating to the securities offered therein, and the offering of      such securities at that time shall be deemed to be the initial bona fide      offering thereof. |
|--------|-----------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | (3)     | To remove from      registration by means of a post-effective amendment any of the securities      being registered which remain unsold at the termination of the      offering. |
|--------|-----------------------------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| B. | The      undersigned registrant hereby undertakes that, for purposes of determining      any liability under the Securities Act, each filing of the registrant’s      annual report pursuant to section 13(a) or section 15(d) of the Exchange      Act (and, where applicable, each filing of an employee benefit plan’s      annual report pursuant to section 15(d) of the Exchange Act) that is      incorporated by reference in the registration statement shall be deemed to      be a new registration statement relating to the securities offered      therein, and the offering of such securities at that time shall be deemed      to be the initial bona fide offeringthereof. |
|----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| C. | Insofar      as indemnification for liabilities arising under the Securities Act may be      permitted to directors, officers and controlling persons of the registrant      pursuant to the foregoing provisions, or otherwise, the registrant has      been advised that in the opinion of the SEC such indemnification is      against public policy as expressed in the Securities Act and is,      therefore, unenforceable. In the event that a claim for indemnification      against such liabilities (other than the payment by the registrant of      expenses incurred or paid by a director, officer or controlling person of      the registrant in the successful defense of any action, suit or      proceeding) is asserted by such director, officer or controlling person in      connection with the securities being registered, the registrant will,      unless in the opinion of its counsel the matter has been settled by      controlling precedent, submit to a court of appropriate jurisdiction the      question whether such indemnification by it is against public policy as      expressed in the Securities Act and will be governed by the final      adjudication of such issue. |
|----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

----

| Signature                                   |   | Capacity                                                                                            |   | Date                          |
|---------------------------------------------|--------|-----------------------------------------------------------------------------------------------------|--------|-------------------------------|
|                                        |   |                                                                                                |   |                          |
| /s/ Robert G. Burton, Sr.                   |   | Chairman      of the Board andChief      Executive Officer(Principal      Executive Officer)        |   |  September      11, 2008 |
| Robert      G. Burton, Sr.                  |   |                                                                                                |   |                          |
|                                        |   |                                                                                                |   |                          |
| /s/ Mark S.      Hiltwein    |   | Chief      Financial Officer(Principal      Financial Officer and PrincipalAccounting      Officer) |   | September      11, 2008       |
| Mark      S. Hiltwein                       |   |                                                                                                |   |                          |
|                                        |   |                                                                                                |   |                          |
| /s/ Gerald S. Armstrong                     |   | Director                                                                                            |   | September      11, 2008       |
| Gerald      S. Armstrong                    |   |                                                                                                |   |                          |
|                                        |   |                                                                                                |   |                          |
| /s/ Patrice M. Daniels                      |   | Director                                                                                            |   | September      11, 2008       |
| Patrice      M. Daniels                     |   |                                                                                                |   |                          |
|                                        |   |                                                                                                |   |                          |
| /s/ Leonard C. Green                        |   | Director                                                                                            |   | September      11, 2008       |
| Leonard      C. Green                       |   |                                                                                                |   |                          |
|                                        |   |                                                                                                |   |                          |
| /s/ Mark J. Griffin                         |   | Director                                                                                            |   | September      11, 2008       |
| Mark      J. Griffin                        |   |                                                                                                |   |                          |
|                                        |   |                                                                                                |   |                          |
| /s/ Robert B. Obernier                      |   | Director                                                                                            |   | September      11, 2008       |
| Robert      B. Obernier                     |   |                                                                                                |   |                          |

----

| Exhibit      No. | Description                                                                                                                                                                                                                                                                                                                                                         |
|------------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 4.1              | Articles      of Incorporation of Cenveo, Inc. (incorporated by reference to Exhibit 3.1      to the Company’s Quarterly Report on Form 10-Q for the quarter ended June      30, 1997, as filed with the SEC on August 14, 1997)                                                                                                                         |
| 4.2              | Amendment      to Articles of Incorporation of Cenveo, Inc. (incorporated by reference to      Exhibit 3.2 to the Company’s Quarterly Report on Form 10-Q for the quarter      ended June 30, 2004, as filed with the SEC on August 2, 2004)                                                                                                             |
| 4.3              | Amendment      to Articles of Incorporation and Certificate of Designations of Series A      Junior Participating Preferred Stock of Cenveo, Inc. (incorporated by      reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K dated      (date of earliest event reported) April 17, 2005, as filed with the SEC on      April 21, 2005)  |
| 4.4              | Amended      and Restated Bylaws of Cenveo, Inc.  (incorporated by reference      to Exhibit 3.2 to the Company’s Current Report on Form 8-K dated (date of      earliest event reported) February 22, 2007, as filed with the SEC on      August 30, 2007)                                                                                    |
| 4.5              | Cenveo,      Inc. 2007 Long-Term Equity Incentive Plan (incorporated by reference to      Exhibit 10.1 to the Company’s Quarterly Report on Form 10-Q for the      quarter ended June 30, 2007, as filed with the SEC on August 8,      2007)                                                                                                            |
| 4.6              | Amendment      to the Cenveo, Inc. 2007 Long-Term Equity Incentive Plan (incorporated by      reference as Exhibit A to the Company’s Definitive 14A, as filed with the      SEC on April 28, 2008)                                                                                                                                                      |
| 5.1              | Opinion      of Timothy M. Davis, the Company’s General Counsel                                                                                                                                                                                                                                                                                          |
| 23.1             | Consent      of Deloitte & Touche LLP                                                                                                                                                                                                                                                                                                                      |
| 23.2             | Consent      of Ernst & Young LLP                                                                                                                                                                                                                                                                                                                          |
| 23.3             | Consent      of Timothy M. Davis (included in Exhibit 5.1)                                                                                                                                                                                                                                                                                                     |
| 24.1             | Powers      of Attorney (included in signature page to this Registration      Statement)                                                                                                                                                                                                                                                                       |

----

----

----