<TABLE> <S> <C>

<PAGE>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM DRKOOP.COM,
INC.'S REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 1999 AND IS QUALIFIED
IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000

<S>                             <C>                     <C>
<PERIOD-TYPE>                   12-MOS                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1998             DEC-31-1999
<PERIOD-START>                             JAN-01-1998             JAN-01-1999
<PERIOD-END>                               DEC-31-1998             DEC-31-1999
<CASH>                                               0                  35,706
<SECURITIES>                                         0                       0
<RECEIVABLES>                                       41                  10,532
<ALLOWANCES>                                         0                       0
<INVENTORY>                                          0                       0
<CURRENT-ASSETS>                                    63                  69,100
<PP&E>                                             377                  11,985
<DEPRECIATION>                                     (71)                 (1,550)
<TOTAL-ASSETS>                                     380                  99,720
<CURRENT-LIABILITIES>                            2,968                  22,798
<BONDS>                                              0                       0
<PREFERRED-MANDATORY>                           18,406                       0
<PREFERRED>                                          1                       0
<COMMON>                                             8                      30
<OTHER-SE>                                     (21,003)                 71,287
<TOTAL-LIABILITY-AND-EQUITY>                       380                  99,720
<SALES>                                             43                   9,431
<TOTAL-REVENUES>                                     0                       0
<CGS>                                                0                       0
<TOTAL-COSTS>                                    9,160                  66,910
<OTHER-EXPENSES>                                     0                       0
<LOSS-PROVISION>                                     0                       0
<INTEREST-EXPENSE>                                  34                   1,344
<INCOME-PRETAX>                                 (9,083)                (56,135)
<INCOME-TAX>                                         0                       0
<INCOME-CONTINUING>                                  0                       0
<DISCONTINUED>                                       0                       0
<EXTRAORDINARY>                                      0                       0
<CHANGES>                                            0                       0
<NET-INCOME>                                    (9,083)                (56,135)
<EPS-BASIC>                                         (3)                     (4)
<EPS-DILUTED>                                       (3)                     (4)


</TABLE>