EX-10.28(xi)



 [ * ] = Certain confidential information contained in this document, marked by brackets, has been omitted and
filed separately with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended. 
  

Exhibit 10.28(xi) 

AMENDMENT NO. 9 TO THE PROCESS DEVELOPMENT
AND CLINICAL SUPPLY AGREEMENT 
 THIS AMENDMENT
NO. 9 (the “Ninth Amendment”), effective as of November 26, 2012 (the “Ninth Amendment Effective Date”) by and between Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer
Straße 65, 88397 Biberach an der Riss, Germany (“BI Pharma”) and FibroGen, Inc., 409 Illinois Street, San Francisco, CA 94158, USA (“FibroGen”), amends the Process Development and Clinical Supply Agreement entered
into by and between BI Pharma and FibroGen on November 29, 2007, as amended pursuant to the letter agreements entered into as of June 26, 2008 and August 18, 2008, Amendment No. 1, effective as of May 28, 2009, Amendment
No. 3, effective as of November 5, 2010, Amendment No. 4, effective as of January 24, 2011, Amendment No. 5, effective as of April 15, 2011, Amendment No. 6, effective as of May 26, 2011, Amendment No. 7,
effective as of January 01, 2012, and Amendment No. 8 (which is under negotiation simultaneously) (hereinafter together the “Supply Agreement”). BI Pharma and FibroGen shall be referred to individually herein as a
“Party”, and collectively as the “Parties”. 
 WHEREAS, FibroGen and BI Pharma agreed to the work plan entitled
“[ * ] (Version of February 2, 2012)” and both parties are now in agreement that (i) some parts of this work plan have been successfully performed by BI Pharma, and (ii) some other parts need to be removed
from said work plan and be replaced by other work packages; 
 WHEREAS, FibroGen additionally wishes to engage BI Pharma to
[ * ], among others [ * ], in compliance with the terms of the Supply Agreement as amended by this Ninth Amendment. 

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which is hereby
acknowledged, the Parties agree as follows: 
  

	 	(1)	Sections 2.1, 2.2 and 4 of the work plan entitled “[ * ] (Version of February 2, 2012)” shall be deleted. The other parts of this work plan, including those portions of the work plan
which have been performed by BI Pharma, shall remain in full force and effect. 

  

	 	(2)	Pursuant to Section 2.2 of the Supply Agreement, additional work packages shall be performed under the Agreement and therefore the Project shall be amended and replaced by the work plan entitled
“[ * ] (Version of November 26, 2012)”, which is attached hereto as Exhibit A and is hereby added as an amendment to Appendix 2 to the Supply Agreement. These additional work packages are 


 

	 	a)	[ * ] (as defined in the Sixth Amendment), [ * ] under the Seventh Amendment that are now deleted according to Section (1) of this Ninth Amendment, and 


 

	 	b)	[ * ], 

 in accordance with the Supply Agreement. 

 

	 	(3)	 This Ninth Amendment, together with the Supply Agreement, contains the entire understanding of the Parties with respect to the subject matter hereof.
Except as otherwise provided herein, the Supply Agreement has not been modified or amended and remains in full 



  
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	Amendment No. 9 to the Process Development and Clinical Supply Agreement	  	 	Confidential	  

  
  

	 	
force and effect. All express or implied agreements and understandings that conflict with the terms of this Ninth Amendment, either oral or written, heretofore made with respect to subject matter
herein are expressly superseded by this Ninth Amendment. 

  

	 	(4)	This Ninth Amendment may be executed in counterparts, each of which shall be deemed an original, and all of which together shall constitute one and the same instrument. Counterparts may be signed and delivered by
facsimile and/or via portable document format (pdf) (or similar format), each of which shall be binding when sent. 

 IN WITNESS WHEREOF, the
Parties have executed this Ninth Amendment to the Supply Agreement as of Ninth Amendment Effective Date. 
 Biberach, February 21, 2013 

BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 

 

							
	ppa.	 		  	ppa.	 	
				
	 [ * ]
	 		  	 [ * ]
	 	
	[ * ]	 		  	[ * ]	 	
	VP Business & Contracts	 		  	Head of Team Biberach – Dep. Legal Germany	 	

 San Francisco, March 25, 2013 

FIBROGEN, INC 
  

											
	 /s/ James Polarek
	 		 	  
	 	
	Name	 	 James W. Polarek
	 		 	Name	 	  
	 	
	Title	 	 VP, Protein Therapeutics and Collagen Development
	 		 	Title	 	  
	 	


  

					
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 [ * ] = Certain confidential
information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended. 









					
	Amendment No. 9 to the Process Development and Clinical Supply Agreement	  	 	Confidential	  

  
  

Exhibit A 
 Work
Scope 
 (Version of November 26, 2012) 

[ * ] 

  

					
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 [ * ] = Certain confidential
information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended.