52536 Federal Register / Vol. 75, No. 165 / Thursday, August 26, 2010 / Notices 

Department of Health and Human 

Services (DHHS). 

ACTION: Notice of availability. 

SUMMARY: This notice announces, for 

review and comment, the availability of 

one new draft toxicological profile on 

unregulated hazardous substances that 

was prepared for the Department of 

Defense (DOD). All toxicological 

profiles issued as ‘‘Drafts for Public 

Comment’’ represent ATSDR’s best 

efforts to provide important 

toxicological information on priority 

hazardous substances. We are seeking 

public comments and additional 

information or reports on studies about 

the health effects of royal demolition 

explosive (RDX), chemical name 

hexahydro-1,3,5-trinitro-1,3,5-triazine, 

also known as cyclonite, for review and 

potential inclusion in the profile. 

ATSDR remains committed to providing 

a public comment period for these 

documents as a means to best serve 

public health and our stakeholders. 

DATES: To be considered, comments on 

this draft toxicological profile must be 

received not later than November 19th, 

2010. Comments received after the close 

of the public comment period will be 

considered at the discretion of ATSDR, 

based upon what is deemed to be in the 

best interest of the general public. 

ADDRESSES: Requests for printed copies 

of the draft toxicological profile should 

be sent via e-mail to cdcinfo@cdc.gov, or 

to Ms. Olga Dawkins, Division of 

Toxicology and Environmental 

Medicine, Agency for Toxic Substances 

and Disease Registry, Mailstop F–62, 

1600 Clifton Road, NE., Atlanta, Georgia 

30333. Electronic access to this 

document is also available at the 

ATSDR Web site: http:// 

www.atsdr.cdc.gov/toxpro2.html. 

Written comments and other data 

submitted in response to this notice and 

to the draft RDX toxicological profile 

should bear the docket control number 

ATSDR–XXX. Send one copy of all 

comments and three copies of all 

supporting documents to the attention 

of Ms. Nickolette Roney, Division of 

Toxicology and Environmental 

Medicine, Agency for Toxic Substances 

and Disease Registry, Mailstop F–62, 

1600 Clifton Road, NE., Atlanta, Georgia 

30333, by the end of the comment 

period. Electronic comments may be 

sent via e-mail to: 

tppubliccomments@cdc.gov. Please 

include RDX in the subject line of the 

e-mail. Because all public comments 

regarding ATSDR toxicological profiles 

are available for public inspection, no 

confidential business information or 

other confidential information should 

be submitted in response to this notice. 

FOR FURTHER INFORMATION CONTACT: Ms. 

Olga Dawkins, Division of Toxicology 

and Environmental Medicine, Agency 

for Toxic Substances and Disease 

Registry, Mailstop F–62, 1600 Clifton 

Road, NE., Atlanta, Georgia 30333, 

telephone (770) 488–3315. Electronic 

access to this document is also available 

at the ATSDR Web site: http:// 

www.atsdr.cdc.gov/toxpro2.html. 

Comments and other data submitted in 

response to this notice and the draft 

toxicological profile should bear the 

docket control number ATSDR–266. 

SUPPLEMENTARY INFORMATION: The 

Superfund Amendments and 

Reauthorization Act (SARA) of 1986 

(Pub. L. 99–499) amended the 

Comprehensive Environmental 

Response, Compensation, and Liability 

Act (CERCLA or Superfund). Section 

211 of SARA also amended Title 10 of 

the U.S. Code, creating the Defense 

Environmental Restoration Program. 

Section 2704(a) of Title 10 of the U.S. 

Code directs the Secretary of Defense to 

notify the Secretary of DHHS of not less 

than 25 of the most commonly found 

unregulated hazardous substances at 

defense facilities. The Secretary of 

DHHS is to prepare toxicological 

profiles of these substances. Each profile 

is to include an examination, summary, 

and interpretation of available 

toxicological information and 

epidemiologic evaluations. This 

information is used to ascertain the 

level of significant human exposure for 

the substance and the associated health 

effects. The toxicological profile 

includes a determination of whether 

adequate information on the health 

effects of each substance is available or 

is in the process of being developed. 

When adequate information is not 

available, ATSDR, in cooperation with 

the National Toxicology Program (NTP), 

may plan a program of research 

designed to determine these health 

effects. 

Although a number of key studies for 

this substance were identified and 

evaluated during the draft profile 

development process, this Federal 

Register notice seeks to solicit any 

additional studies, particularly 

unpublished data and ongoing studies. 

These studies will be evaluated for 

possible addition to the profile now or 

in the future. 

The draft toxicological profile will be 

made available to the public on or about 

August 20, 2010. 

Hazardous substance CAS No. 

RDX .......................................... 121–82–4 

Dated: August 20, 2010. 

Kenneth Rose, 

Director, Office of Policy, Planning, and 

Evaluation, National Center for 

Environmental Health/Agency for Toxic 

Substances and Disease Registry. 

[FR Doc. 2010–21298 Filed 8–25–10; 8:45 am] 

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DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Center for Research 

Resources; Notice of Closed Meeting 

Pursuant to section 10(d) of the 

Federal Advisory Committee Act, as 

amended (5 U.S.C. App.), notice is 

hereby given of the following meeting. 

The meeting will be closed to the 

public in accordance with the 

provisions set forth in sections 

552b(c)(4) and 552b(c)(6), Title 5 U.S.C., 

as amended. The grant applications and 

the discussions could disclose 

confidential trade secrets or commercial 

property such as patentable material, 

and personal information concerning 

individuals associated with the grant 

applications, the disclosure of which 

would constitute a clearly unwarranted 

invasion of personal privacy. 

Name of Committee: National Center for 

Research Resources Initial Review Group, 

Comparative Medicine Review Committee 

CMRC. 

Date: October 14, 2010. 

Time: 8 a.m. to 5 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: Hilton Washington/Rockville, 1750 

Rockville Pike, Rockville, MD 20852. 

Contact Person: Bonnie B. Dunn, PhD, 

Scientific Review Officer, National Center for 

Research Resources, or National Institutes of 

Health, 6701 Democracy Blvd., 1 Democracy 

Plaza, Room 1074, MSC 4874, Bethesda, MD 

20892–4874. 301–435–0824. 

dunnbo@mail.nih.gov. 

(Catalogue of Federal Domestic Assistance 

Program Nos. 93.306, Comparative Medicine; 

93.333, Clinical Research; 93.371, Biomedical 

Technology; 93.389, Research Infrastructure, 

93.306, 93.333; 93.702, ARRA Related 

Construction Awards., National Institutes of 

Health, HHS) 

Dated: August 20, 2010. 

Jennifer Spaeth, 

Director, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2010–21312 Filed 8–25–10; 8:45 am] 

BILLING CODE 4140–01–P 

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