Exhibit 21.1

MEDCO HEALTH SOLUTIONS, INC.

List of Subsidiaries



|                                                               |  |                                        
|-------------------------------------------------------------- |  | ---------------------------------------
|Subsidiary Name                                                |  | Jurisdiction of Incorporation/Formation
|Accredo Health, Incorporated                                   |  | Delaware                               
|Accredo Health Group, Inc.                                     |  | Delaware                               
|Accredo Health Services (Infusion), Inc.                       |  | Delaware                               
|Accredo Health Resources, Inc. (New York)                      |  | New York                               
|AHG of New York, Inc.                                          |  | New York                               
|BioPartners In Care, Inc.                                      |  | Missouri                               
|Clinical Business Solutions, Inc.                              |  | Delaware                               
|Hemophilia Resources of America, Inc.                          |  | New Jersey                             
|HRA Holding Corp.                                              |  | New Jersey                             
|Home Healthcare Resources, Inc.                                |  | Pennsylvania                           
|Home Healthcare Resources, Limited                             |  | Pennsylvania                           
|Medco at Home, L.L.C.                                          |  | Delaware                               
|Medco Containment Insurance Company of New Jersey              |  | New Jersey                             
|Medco Containment Insurance Company of New York                |  | New York                               
|Medco Containment Life Insurance Company                       |  | Pennsylvania                           
|Medco Health, L.L.C.                                           |  | Delaware                               
|Medco Health New York Independent Practice Association, L.L.C. |  | New York                               
|Medco Health Puerto Rico, L.L.C.                               |  | Delaware                               
|Medco Health Receivables, L.L.C.                               |  | Delaware                               
|Medco Health Solutions of Columbus North, Ltd.                 |  | Ohio                                   
|Medco Health Solutions of Columbus West, Ltd.                  |  | Ohio                                   
|Medco Health Solutions of Fairfield, L.L.C.                    |  | Pennsylvania                           
|Medco Health Solutions of Franklin Lakes, L.L.C.               |  | New Jersey                             
|Medco Health Solutions of Henderson, Nevada, L.L.C.            |  | Delaware                               
|Medco Health Solutions of Hidden River, L.C.                   |  | Florida                                
|Medco Health Solutions of Las Vegas, L.L.C.                    |  | Nevada                                 
|Medco Health Solutions of Netpark, L.L.C.                      |  | Delaware                               
|Medco Health Solutions of North Versailles, L.L.C.             |  | Pennsylvania                           
|Medco Health Solutions of Richmond, L.L.C.                     |  | Virginia                               
|Medco Health Solutions of Spokane, Inc.                        |  | Washington                             
|Medco Health Solutions of Texas, L.L.C.                        |  | Texas                                  
|Medco Health Solutions of Willingboro, L.L.C.                  |  | New Jersey                             
|medcohealth.com, L.L.C.                                        |  | New Jersey                             
|Medco Services Puerto Rico, Inc.                               |  | Delaware                               
|Merck-Medco of Willingboro Urban Renewal, L.L.C.               |  | New Jersey                             
|MWD Insurance Company                                          |  | New York                               
|National Rx Services Inc. of Missouri                          |  | Missouri                               
|National Rx Services No. 3, Inc. of Ohio                       |  | Ohio                                   
|NJRE, L.L.C.                                                   |  | New Jersey                             
|Replacement Distribution Center, Inc.                          |  | Ohio                                   
|Systemed, L.L.C.                                               |  | Delaware