Exhibit 21.1
 MEDCO HEALTH SOLUTIONS, INC.
List of Wholly-Owned Subsidiaries
As of December 27, 2008
 Jurisdiction ofSubsidiary Name
    
    Incorporation/FormationAccredo Care Network, Inc.
    
    DelawareAccredo Health, Incorporated
    
    DelawareAccredo Health Group, Inc.
    
    DelawareAccredo Health Resources, Inc. (New York)
    
    New YorkAccredo Health Services (Infusion), Inc.
    
    DelawareAHG of New York, Inc.
    
    New YorkBioPartners In Care, Inc.
    
    MissouriCCS America, Inc.
    
    CaliforniaCCS Infusion Management, LLC
    
    DelawareCCSI Holding 3, LLC
    
    DelawareClinical Business Solutions, Inc.
    
    DelawareCritical Care Systems of New York, Inc.
    
    New YorkCritical Care Systems, Inc.
    
    DelawareHCS, Inc.
    
    DelawareHemophilia Resources of America, Inc.
    
    New JerseyHome Healthcare Resources, Inc.
    
    PennsylvaniaHome Healthcare Resources, Limited
    
    PennsylvaniaHRA Holding Corp.
    
    New JerseyInfinity Infusion Care, Ltd.
    
    TexasInfinity Infusion II, LLC
    
    DelawareInfinity Infusion, LLC
    
    DelawareIntelliCare, Inc.
    
    DelawareLiberty Direct Services Corporation
    
    DelawareLiberty Healthcare Group, Inc.
    
    DelawareLiberty Healthcare Pharmacy of Nevada, LLC
    
    NevadaLiberty Lane Condominium Association, Inc.
    
    FloridaLiberty Lane Development Company, Inc.
    
    FloridaLiberty Medical Response, Inc.
    
    DelawareLiberty Medical Supply, Inc.
    
    FloridaMedco at Home, L.L.C.
    
    DelawareMedco CDUR, L.L.C.
    
    DelawareMedco CHP, L.L.C.
    
    DelawareMedco Containment Insurance Company of New York
    
    New YorkMedco Containment Life Insurance Company
    
    PennsylvaniaMedco Europe, L.L.C.
    
    DelawareMedco Health, L.L.C.
    
    DelawareMedco Health New York Independent Practice Association, L.L.C.
    
    New YorkMedco Health Puerto Rico, L.L.C.
    
    DelawareMedco Health Receivables, L.L.C.
    
    DelawareMedco Health Services, Inc.
    
    DelawareMedco Health Solutions of Columbus North, Ltd.
    
    OhioMedco Health Solutions of Columbus West, Ltd.
    
    OhioMedco Health Solutions of Fairfield, L.L.C.
    
    PennsylvaniaMedco Health Solutions of Franklin Lakes, L.L.C.
    
    New JerseyMedco Health Solutions of Henderson, Nevada, L.L.C.
    
    DelawareMedco Health Solutions of Hidden River, L.C.
    
    FloridaMedco Health Solutions of Indiana, L.L.C.
    
    DelawareMedco Health Solutions of Las Vegas, L.L.C.
    
    NevadaMedco Health Solutions of Netpark, L.L.C.
    
    DelawareMedco Health Solutions of North Versailles, L.L.C.
    
    PennsylvaniaMedco Health Solutions of Richmond, L.L.C.
    
    VirginiaMedco Health Solutions of Spokane, Inc.
    
    WashingtonMedco Health Solutions of Texas, L.L.C.
    
    TexasMedco Health Solutions of Willingboro, L.L.C.
    
    New Jerseymedcohealth.com, L.L.C.
    
    New JerseyMerck-Medco of Willingboro Urban Renewal, L.L.C.
    
    New JerseyMWD Insurance Company
    
    New YorkNational Rx Services Inc. of Missouri
    
    MissouriNational Rx Services No. 3, Inc. of Ohio
    
    OhioPolyMedica Corporation
    
    MassachusettsReplacement Distribution Center, Inc.
    
    OhioSystemed, L.L.C.
    
    Delaware