<PAGE>

                                                                   EXHIBIT 10.46


August 25, 2000




Gregory A. Gould


Dear Greg:

In connection with the promotion to Chief Financial Officer we have extended to
you, this letter confirms that if you accept this position and Colorado MEDtech,
Inc. (the "Company") subsequently terminates your employment within twelve (12)
months after a "change in control of the Company" (defined below)  for a reason
other than "Cause" (defined below), or if you terminate your employment for
"Good Reason" (defined below), the Company will continue your base salary
payments for a period of twelve (12) months following the date of termination.
If after termination you elect to continue your group health insurance coverage
through COBRA, the Company will also pay the monthly medical insurance premium
payment required to maintain your then current medical insurance coverage (less
any amount you are paying for such insurance at the time of termination, of
which payment from you will be required by the beginning of each month) after
termination for twelve (12) months or until you obtain new employment, whichever
occurs first.

For purposes of this letter, your employment with the Company shall be deemed
terminated for "Cause" only if it is terminated by the Company for:

          (i)   misappropriation of corporate confidential information (or
unauthorized disclosure thereof) or funds by you or with your direct
involvement;

          (ii)  fraud, embezzlement, theft or dishonesty by you reasonably
suspected by the Company; or

          (iii) negligent or willful misconduct or dereliction of duty by you;
provided, however, that no discharge shall be deemed for Cause under this clause
-----------------
(iii) unless you shall have first received written notice from the Company
advising you of the specific acts or omissions alleged to constitute such
negligent or willful misconduct, and such misconduct continues uncured by you
for a period of twenty (20) days.

Upon the occurrence of any of the following events, you may terminate your
employment for good reason ("Good Reason") by written notice to the Company:

          (i)   the closing of a sale by the Company of substantially all of its
     assets to not more than two (2) buyers; or
<PAGE>

Gregory A. Gould
August 25, 2000
Page 2

          (ii)   if you elect to remain employed after a "change in control of
     the Company" (defined below) and thereafter, during the twelve (12) months
     after the change in control, you: (1) are demoted from the position you
     held prior to the change in control; (2) are assigned duties inconsistent
     with your roles and responsibilities prior to the change in control; (3)
     are required to materially increase your travel obligations from those you
     had prior to the change in control; (4) are relocated to an office or site
     greater than 50 miles from your location prior to the change in control; or
     (5) your compensation or benefits are materially reduced (including paid
     time off and vacation). A "change of control of the Company" will be deemed
     to occur under either of the following circumstances: (A) any "person" (as
     that term is used in Section 13(d) and 14(d) of the Exchange Act), other
     than the Company or any "person" who on the date hereof is a director or
     officer of the Company, is or becomes the "beneficial owner" (as defined in
     Rule 13d-3 under the Exchange Act), directly or indirectly, of securities
     of the Company representing forty percent (40%) or more of the combined
     voting power of the Company's then outstanding securities, or (B) if, at
     any time during any period of two consecutive years, individuals who at the
     beginning of such period constitute the Board cease for any reason to
     constitute at least a majority thereof, unless the election of each
     director who was not a director at the beginning of such period has been
     approved in advance by directors representing at least two-thirds of the
     directors then in office who were directors at the beginning of the period.

In the event you retain counsel to enforce this letter the Company will
reimburse you for reasonable attorneys fees and costs associated with such
effort.  If any action at law or in equity is necessary to enforce or interpret
the terms of this letter, the prevailing party shall be entitled to reasonable
attorneys fees, costs and necessary disbursements in addition to any other
relief to which that party may be entitled.

This letter shall not by itself constitute an agreement for a specific term of
employment.  EITHER YOU OR THE COMPANY MAY TERMINATE YOUR EMPLOYMENT AT ANY TIME
AND FOR ANY REASON.

COLORADO MEDTECH, INC.                            AGREED AND ACCEPTED:



By:  /s/ Stephen K. Onody                         /s/ Gregory A. Gould
   -------------------------------------          ---------------------------
   Stephen K. Onody,                              Gregory A. Gould
   President and Chief Executive Officer