Exhibit 12.1

MEDCO HEALTH SOLUTIONS, INC.

Computation of Ratios of Earnings to Fixed Charges

(In millions, except ratio data)



|                                      |  |              |         |              |   |              |  |              |       |              |   |       |  |   |      
|------------------------------------- |  | ------------ | ------- | ------------ | - | ------------ |  | ------------ | ----- | ------------ | - | ----- |  | - | -----
|                                      |  | Years Ended 
|                                      |  | Dec. 31,2005 |         | Dec. 25,2004 |   | Dec. 27,2003 |  | Dec. 28,2002 |       | Dec. 29,2001
|Income before taxes                   |  | $            | 952.9   |              | $ | 806.3        |  | $            | 728.7 |              | $ | 620.3 |  | $ | 518.3
|One-third of rents                    |  |              | 18.1    |              |   | 16.9         |  |              | 20.2  |              |   | 17.1  |  |   | 13.5 
|Interest expense                      |  |              | 73.9    |              |   | 69.1         |  |              | 29.3  |              |   | 0.3   |  |   | 0.9  
|Equity loss from affiliates           |  |              | 3.6     |              |   | 5.0          |  |              | 5.8   |              |   | 4.8   |  |   | 1.8  
|                                      |  |              |         |              |   |              |  |              |       |              |   |       |  |   |      
|Earnings                              |  | $            | 1,048.5 |              | $ | 897.3        |  | $            | 784.0 |              | $ | 642.5 |  | $ | 534.5
|                                      |  |              |         |              |   |              |  |              |       |              |   |       |  |   |      
|One-third of rents                    |  | $            | 18.1    |              | $ | 16.9         |  | $            | 20.2  |              | $ | 17.1  |  | $ | 13.5 
|Interest expense                      |  |              | 73.9    |              |   | 69.1         |  |              | 29.3  |              |   | 0.3   |  |   | 0.9  
|                                      |  |              |         |              |   |              |  |              |       |              |   |       |  |   |      
|Fixed charges                         |  | $            | 92.0    |              | $ | 86.0         |  | $            | 49.5  |              | $ | 17.4  |  | $ | 14.4 
|                                      |  |              |         |              |   |              |  |              |       |              |   |       |  |   |      
|Ratio of earnings to fixed charges(1) |  |              | 11.4    |              |   | 10.4         |  |              | 15.8  |              |   | 36.9  |  |   | 37.1 
|                                      |  |              |         |              |   |              |  |              |       |              |   |       |  |   |      

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|(1) | The ratio was calculated by dividing the sum of the fixed charges into the sum of the
earnings and fixed charges. In calculating this ratio, earnings include income before income taxes and before fixed charges. Fixed charges include interest expense and one-third of all rent expense (considered representative of the interest factor).
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