**UNITED STATESSECURITIES AND EXCHANGE COMMISSION**Washington, D.C. 20549

**FORM 10-Q/A**

**Amendment No. 1**

(Mark One)

**[ X ]****QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934**

For the quarterly period ended **September 30, 2009**

[   ] **TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES****EXCHANGE ACT OF 1934**

For the transition period from ________ to ________

**COMMISSION FILE NUMBER****000-28911**

**CANNABIS SCIENCE, INC.**(Exact name of registrant as specified in its charter)

| **Nevada**

**91-1869677**

(State or other jurisdiction of incorporation or

(I.R.S. Employer Identification No.)

organization)

 

 

 

**6946 N Academy Blvd, Suite B #254**

**Colorado Springs CO**

 

**80918**

(Address of principal executive offices)

(Zip code)

**(888) 889-0888**

(Registrant's telephone number, including area code)

**Not Applicable**(Former name, former address and former fiscal year, if changed since last report)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. **Yes [X]**   No [   ]

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.
Large accelerated filer [   ]

Accelerated filer [   ]

Non-accelerated filer [   ] (Do not check if a smaller reporting company)

**Smaller reporting company [X]**

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes [   ]   **No [X]**

Indicate the number of shares outstanding of each of the issuer's classes of common stock, as of the latest practicable date: **As of November 16, 2009, there were 25,747,279 shares of Common Stock of the issuer outstanding.**

                               
**EXPLANATORY NOTE**

This Amendment No. 1 on Form 10-Q/A (this “Amendment”) amends the Registrant’s Amended Quarterly Report on Form 10-Q for the fiscal quarter ended September 30, 2009, which the Registrant previously filed with the Securities and Exchange Commission on November 19, 2009 (the “Original Filing”).  The Registrant is filing this Amendment to include corrected certifications worded exactly as required by Regulation S-K Item 601(b)(31).  Except as set forth above, the Original Filing has not been amended, updated or otherwise modified.  Other events occurring after the filing of the Form 10-Q/A or other disclosures necessary to reflect subsequent events have been addressed in our reports filed with the Securities and Exchange Commission subsequent to the filing of this Form 10-Q/A.

**SIGNATURES**

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

********CANNABIS SCIENCE, INC.********           
Date: March 17, 2010
 
*By:  /s/ Dr. Robert Melamede
 

 

**Dr. Robert Melamede**

 

 

Chief Executive Officer, Director
         
Date: March 17, 2010
By:  /s/ *Richard Cowen*
**Richard Cowen**

Chief Financial Officer, Director
  
                                 
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