55860 Federal Register / Vol. 73, No. 188 / Friday, September 26, 2008 / Notices 

specifically, compounds derived from 

Formula I, wherein B is NR4 and 

wherein R4 is not CH3 (methyl group) to 

treat psychiatric and neurological 

disorders. 

DATES: Only written comments and/or 

applications for a license which are 

received by the NIH Office of 

Technology Transfer on or before 

November 25, 2008 will be considered. 

ADDRESSES: Requests for copies of the 

patent application, inquiries, comments, 

and other materials relating to the 

contemplated exclusive license should 

be directed to: Charlene A. Sydnor, 

Ph.D., Technology Licensing Specialist, 

Office of Technology Transfer, National 

Institutes of Health, 6011 Executive 

Boulevard, Suite 325, Rockville, MD 

20852–3804; Telephone: (301) 435– 

4689; Facsimile: (301) 402–0220; e-mail: 

sydnorc@mail.nih.gov. 

SUPPLEMENTARY INFORMATION: This 

technology relates to the synthesis of 

novel dopamine transport inhibitors and 

their use to treat mental disorders. The 

inventors developed benztropinamine 

analogs by replacing the 

benzhydrylether moiety of benztropine 

and its analogs with the isosteric 

benzhydrylamine system in order to 

produce more stable compounds with 

increased solubility and bioavailability 

for improved therapeutic formulation 

and utility. These compounds have a 

high affinity for the dopamine 

transporter and inhibit dopamine 

uptake, but do not produce a significant 

stimulation of locomotor activity or 

cocaine-like subjective effects in a drug 

discrimination model. These 

compounds are useful for the treatment 

of mental disorders such as conduct 

disorders, alcohol addiction, tobacco 

addiction, nicotine addiction, drug 

addiction, sleep disorders, inhalation 

disorders, Parkinsonism including 

Parkinson’s disease, female and male 

orgasmic disorders, female and male 

sexual arousal disorders, hypoactive 

sexual desire disorders, and anxiety 

and/or depression disorders. These 

compounds are also useful as imaging 

probes for detecting cocaine binding 

sites, as well as monitoring or 

diagnosing Parkinson’s disease. 

The prospective exclusive license will 

be royalty bearing and will comply with 

the terms and conditions of 35 U.S.C. 

209 and 37 CFR Part 404.7. The 

prospective exclusive license may be 

granted unless within sixty (60) days 

from the date of this published notice, 

the NIH receives written evidence and 

argument that establishes that the grant 

of the license would not be consistent 

with the requirements of 35 U.S.C. 209 

and 37 CFR Part 404.7. 

Applications for a license in the field 

of use filed in response to this notice 

will be treated as objections to the grant 

of the contemplated exclusive license. 

Comments and objections submitted to 

this notice will not be made available 

for public inspection and, to the extent 

permitted by law, will not be released 

under the Freedom of Information Act, 

5 U.S.C. 552. 

Dated: September 17, 2008. 

Richard U. Rodriguez, 

Director, Division of Technology Development 

and Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. E8–22611 Filed 9–25–08; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

[Docket No. DHS–2008–0102] 

National Protection and Programs 

Directorate; Designation of the SectorSpecific Agency for the Critical 

Manufacturing Sector and Resulting 

Changes in the National Infrastructure 

Protection Plan 

AGENCY: National Protection and 

Programs Directorate, Office of 

Infrastructure Protection, DHS. 

ACTION: Notice of Sector Specific 

Agency designation for Critical 

Manufacturing. 

SUMMARY: This notice informs the public 

that the Secretary, Department of 

Homeland Security (DHS), has 

designated the DHS Office of 

Infrastructure Protection (IP) as the 

Sector-Specific Agency (SSA) for the 

Critical Manufacturing Sector under the 

National Infrastructure Protection Plan 

(NIPP). IP will now move forward with 

the organization and coordination 

processes identified in the NIPP for 

establishing a new critical infrastructure 

and key resources (CIKR) sector. These 

initial steps will include establishing 

Government and Sector Coordinating 

Councils, which will begin the process 

of full integration into the CIKR Sector 

Partnership, implementation of the 

NIPP Risk Management Framework and 

development of the Critical 

Manufacturing Sector Specific Plan. 

This designation also includes 

language changes to the NIPP 

identifying the new sector, which will 

take affect immediately and remain in 

effect until the NIPP is rewritten and 

published in 2009. These changes will 

include adding the Critical 

Manufacturing sector and its SSA to 

those sections of the NIPP where sectors 

and their SSAs are listed, referenced, or 

described, and amending the last 

sentence of the definition of ‘‘Sector’’ in 

the Glossary to read, ‘‘The NIPP 

addresses the 17 CIKR sectors 

enumerated in HSPD–7 and any 

additional sectors created by the 

Secretary of Homeland Security 

pursuant to HSPD–7.’’ 

FOR FURTHER INFORMATION CONTACT: 

Larry L. May, Deputy Director, NIPP 

Program Office, Partnership and 

Outreach Division, Office of 

Infrastructure Protection, National 

Protection and Programs Directorate, 

Department of Homeland Security, 

Washington, DC 20528, 703–235–3648 

or NIPP@dhs.gov. 

Dated: September 17, 2008. 

R. James Caverly, 

Director, Partnership and Outreach Division, 

Office of Infrastructure Protection, 

Department of Homeland Security. 

[FR Doc. E8–22609 Filed 9–25–08; 8:45 am] 

BILLING CODE 4410–10–P 

DEPARTMENT OF HOMELAND 

SECURITY 

U.S. Customs and Border Protection 

Notice of Issuance of Final 

Determination Concerning Certain 

Mesh Dressing 

AGENCY: U.S. Customs and Border 

Protection, Department of Homeland 

Security. 

ACTION: Notice of final determination. 

SUMMARY: This document provides 

notice that U.S. Customs and Border 

Protection (‘‘CBP’’) has issued a final 

determination concerning the country of 

origin of certain mesh dressing known 

as TegadermTM Ag Mesh Dressing. 

Based upon the facts presented, CBP has 

concluded in the final determination 

that the United States is the country of 

origin of the TegadermTM Ag Mesh 

Dressing for purposes of U.S. 

Government procurement. 

DATES: The final determination was 

issued on September 22, 2008. A copy 

of the final determination is attached. 

Any party-at-interest, as defined in 19 

CFR 177.22(d), may seek judicial review 

of this final determination within 

October 27, 2008. 

FOR FURTHER INFORMATION CONTACT: 

Cynthia Reese, Valuation and Special 

Programs Branch, Regulations and 

Rulings, Office of International Trade 

(202–572–8812). 

SUPPLEMENTARY INFORMATION: Notice is 

hereby given that on September 22, 

2008, pursuant to subpart B of part 177, 

Customs and Border Protection (CBP) 


jlentini on PROD1PC65 with NOTICES